LOCUS       DAVBDR010000001        93991 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.001, whole genome shotgun sequence.
ACCESSION   DAVBDR010000001 DAVBDR010000000
VERSION     DAVBDR010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 93991)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 93991)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..93991
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.001"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            1..235
                     /locus_tag="VQ540_000001"
                     /pseudo
     CDS             1..235
                     /locus_tag="VQ540_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
     gene            232..450
                     /locus_tag="VQ540_000002"
     CDS             232..450
                     /locus_tag="VQ540_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2543890.1"
                     /translation="MSISPRFEALEQAIASKDLEKVREAFKKMNSTWTINESVVRDNS
                     TAHYGRVETAISFLPSSMETEPTDESGT"
     gene            complement(507..791)
                     /locus_tag="VQ540_000003"
     CDS             complement(507..791)
                     /locus_tag="VQ540_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HET2543891.1"
                     /translation="MARKETMAERKYCKMKKDIHPEYRPVVFMDTTTGYQFLSGSTKR
                     SNETVEFEGETYPLIRVEISSDSHPFYTGRQKFTQADGRVDRFNKKYGLK"
     gene            complement(845..1780)
                     /locus_tag="VQ540_000004"
     CDS             complement(845..1780)
                     /locus_tag="VQ540_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HET2543892.1"
                     /translation="MEICQQILEKIKEYNTIIIHRHMKPDPDALGSQVGLKALLEHHF
                     PEKTIKAVGFDEPTLTWMAEMDLVEDRAYQGALVIVCDTANTARIDDKRYSQGDFLIK
                     IDHHPNDDVYGDLSWVDTSSSSASEMITLFAQTTQLALADRDAELLFAGIVGDTGRFL
                     YPSTTARTLRLAAYLREHNFDFAALTRKMDTMSYKIAKLQGYIYDHLEVDENGAARVI
                     LSQKILKQYNVTDAETAAIVGAPGRIDSVSLWGIFVEQADGHYRVRLRSKIHPINEIA
                     KEHDGGGHPLASGANSYSLEENEIIYQKLKNLLKN"
     gene            1884..2327
                     /locus_tag="VQ540_000005"
     CDS             1884..2327
                     /locus_tag="VQ540_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HET2543893.1"
                     /translation="MALAKIVFASMTGNTEEIADIVADKLRDLGLDVDVDECTTVDAS
                     DFLEADIAIVATYTYGDGELPDEMMDFYEDLADLNLNGKIYGVVGSGDTFYDEFCKAV
                     DDFDRVFVSTGAEKGSECVKVDLSAEEEDIERLEQFAEELAAKVG"
     gene            2443..2709
                     /locus_tag="VQ540_000006"
     CDS             2443..2709
                     /locus_tag="VQ540_000006"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HET2543894.1"
                     /translation="MDLDIIRQEIDQIDDQIVKLLEERMHLVEGVVAYKKASGKPILD
                     TKREEVIFEKVRSRVEDKRYQETIVATFSYILKRSRDYQDQNIK"
     gene            2706..3080
                     /gene="crcB"
                     /locus_tag="VQ540_000007"
     CDS             2706..3080
                     /gene="crcB"
                     /locus_tag="VQ540_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HET2543895.1"
                     /translation="MKKEQFYPLGIFLAAMLGGLVRYLVSTWLPASPDFPWGTLFVNY
                     LGIFCLIFLVKGYLVYKGTSKGLILALGTGFCGGLTTFSSLMLDTVKLLDTGRYFSLV
                     LYLLLSIGGGLLLAYYLGRKKW"
     gene            3074..3403
                     /gene="crcB"
                     /locus_tag="VQ540_000008"
     CDS             3074..3403
                     /gene="crcB"
                     /locus_tag="VQ540_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000237393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HET2543896.1"
                     /translation="MVIVYLAIACGLGALVRYFFSRYNQASKLPLGTLIANLLGCFLI
                     GVFYNHVESKEVYAILATGFCGGLTTFSTLNDELQRLLSDKKVFYSYLTLTYIGGLVA
                     IFLGILL"
     gene            3522..3869
                     /gene="rplS"
                     /locus_tag="VQ540_000009"
     CDS             3522..3869
                     /gene="rplS"
                     /locus_tag="VQ540_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HET2543897.1"
                     /translation="MNPLIQSLTEGQLRTDIPSFRPGDTVRVHAKVVEGNRERIQIFE
                     GVVIARKGAGISENYTVRKISNGVGVERIFPIHTPRVEKIEVVRYGKVRRAKLYYLRA
                     LQGKAARIKEIRR"
     gene            3912..3983
                     /locus_tag="VQ540_000010"
     tRNA            3912..3983
                     /locus_tag="VQ540_000010"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3945..3947,aa:Arg,seq:cct)
     gene            complement(4150..5148)
                     /locus_tag="VQ540_000011"
     CDS             complement(4150..5148)
                     /locus_tag="VQ540_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001008999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAP domain-containing protein"
                     /protein_id="HET2543898.1"
                     /translation="MNFFSKLFNLKQNNHNRDTNSDCNNFYLNELECGLTPGQLILID
                     WTQKTGRNYNFPRYFKYSLQIDPESTHNQLYKLGYFTKNKTLSYLTVVELKTILSKHN
                     LATSGKKAELITRIINNVNIDNLDIPFEFKLTKEAQNLIIEHSDYIKAYYDKDISMED
                     YCKEKNNISFKATFGDIKWSLLNKQAHRNTVSGDFGCLSNTRKAQGRHLEQEGNIKHA
                     LIYYIESLIITISGLENNFSATDYPVYYPDSIPDYSLKHIQTLMESLSDDDYDFAFDE
                     ALFRFSILNANHFLSKEDIDYLRVNLPRSTAEEINNYLKKYECYSPLNNLELDDFE"
     gene            complement(5191..5997)
                     /gene="yidA"
                     /locus_tag="VQ540_000012"
     CDS             complement(5191..5997)
                     /gene="yidA"
                     /locus_tag="VQ540_000012"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000023490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HET2543899.1"
                     /translation="MSIKLIAVDIDGTLVNSQKEITPEVFSAIQDAKEAGVKVVIATG
                     RPIAGVAKLLDDLQLRDQGDYVVTFNGALVQETATGHEIISESLTYEDYLDMEFLSRK
                     LGVHMHAITKDGIYTANRNIGKYTVHESTLVSMPIFYRTPEEMAGKEIVKCMFIDEPE
                     ILDAAIEKIPAEFYERYSINKSAPFYLELLKKNVDKGSAITHLAEKLGLTKDETMAIG
                     DEENDRPMLEVVGNPVVMENGNPEIKKIAKYITKTNDESGVAHAIRTWVL"
     gene            complement(6010..7314)
                     /locus_tag="VQ540_000013"
     CDS             complement(6010..7314)
                     /locus_tag="VQ540_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HET2543900.1"
                     /translation="MNEKVFRDPVHNYIHVNNQIIYDLINTKEFQRLRRIKQLGTSSY
                     TFHGGEHSRFSHCLGVYEIARRITEIFEEKYPEEWNPAESLLTVTAALLHDLGHGAYS
                     HTFENLFDTDHEAITQEIIQNPETEIHQVLLQVAPDFPEKVASVIDHTYPNKQVVQLI
                     SSQIDADRMDYLLRDSYFTGASYGEFDLTRILRVIRPVENGIAFQRNGMHAIEDYVLS
                     RYQMYMQVYFHPATRAMEVLLQNLLKRAKELYPEDKNFFARTSPHLLPFFEKNVTLTD
                     YLALDDGVMNTYFQLWMTSPDKILADLSQRFVNRKVFKSITFSQEDQDQLTSMRKLVE
                     DIGFDPDYYTAIHKNFDLPYDIYRPESQNPRTQIEILQKNGELAELSSLSPIVQSLAG
                     SRHGDNRFYFPKEMLDQNSIFASITQQFLHLIENDHFTPNKN"
     gene            7386..7763
                     /locus_tag="VQ540_000014"
     CDS             7386..7763
                     /locus_tag="VQ540_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HET2543901.1"
                     /translation="MKIRMRNTIQFDEQLEVIDQLYDVEVHEKGDYSYLLFYNEEKEK
                     VVIKFHGQELMMSRFSNPKTIMRFLKDSDSLAYIPTPMGMQEFIIQTSHYQVDRQKIE
                     LDYQLQNQEGHPFASYQLEITWG"
     gene            7854..8186
                     /locus_tag="VQ540_000015"
     CDS             7854..8186
                     /locus_tag="VQ540_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009660419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HET2543902.1"
                     /translation="MEIEKTNRMNALFEFYAALLTDKQMNYIELYYADDYSLAEIAEE
                     FGVSRQAVYDNIKRTEKILEDYEMKLHMYSDYIVRSQIFDQILERYPKDDFLQEQIEI
                     LTSIDNRE"
     gene            8198..9769
                     /gene="ffh"
                     /locus_tag="VQ540_000016"
     CDS             8198..9769
                     /gene="ffh"
                     /locus_tag="VQ540_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HET2543903.1"
                     /translation="MAFESLTERLQNVFKNLRKKGKISESDVQEATKEIRLALLEADV
                     ALPVVKDFIKKVRERAVGHEVIDTLNPAQQIIKIVDEELTAVLGSDTAEIIKSPKIPT
                     IIMMVGLQGAGKTTFAGKLANKLKKEENARPLMIAADIYRPAAIDQLKTLGQQIDVPV
                     FALGTEVPAVEIVRQGLEQAQTNHNDYVLIDTAGRLQIDELLMNELRDVKALAQPNEI
                     LLVVDAMIGQEAANVAREFNAQLEVTGVILTKIDGDTRGGAALSVRHITGKPIKFTGT
                     GEKITDIETFHPDRMSSRILGMGDMLTLIEKASQEYDEQKALEMAEKMRENTFDFNDF
                     IDQLDQVQNMGPMEDLLKMIPGMANNPALQNMKVDERQIARKRAIVSSMTPEERENPD
                     LLNPSRRRRIAAGSGNTFVEVNKFIKDFNQAKQLMQGVMSGDMNKMMKQMGINPNNLP
                     KNMPNMGGMDMSALEGMMGQGGMPDLSALGGAGMPDMSQMFGGGLKGKIGEFAMKQSM
                     KRMANKMKKAKKKRK"
     gene            complement(9964..11247)
                     /locus_tag="VQ540_000017"
     CDS             complement(9964..11247)
                     /locus_tag="VQ540_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007554578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HET2543904.1"
                     /translation="MKQESTVDLLLDVDQRPSAGKGILLSFQHVFAMFGATILVPLIL
                     GMPVSVALFASGVGTLIYMIATGFKVPVYLGSSFAFITAMSLAMKEMGGDVSAAQTGV
                     ILTGLVYVLVATSIRFVGTKWIDKLLPPIIIGPMIIVIGLGLAGSAVTNAGLVADGNW
                     KNALVAVVTFLIAAFINTKGKGFLRIIPFLFAIIGGYLFALTLGLVDFTPVLKANWFE
                     IPGFYLPFSTGGAFKEYNLYFGPEAIAILPIAIVTISEHIGDHTVLGQICGRQFLKEP
                     GLHRTLLGDGIATSVSAFLGGPANTTYGENTGVIGMTRIASVSVIRNAAFIAIALSFL
                     GKFTALISTIPNAVLGGMSILLYGVIASNGLKVLIKERVDFAQMRNLIIASAMLVLGL
                     GGAILKLGPVTLSGTALSAMTGIILNLILPYENKD"
     gene            complement(11550..12263)
                     /gene="rsmG"
                     /locus_tag="VQ540_000018"
     CDS             complement(11550..12263)
                     /gene="rsmG"
                     /locus_tag="VQ540_000018"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HET2543905.1"
                     /translation="MKPKTFYNLLAEQNLPLSDQQKEQFERYFELLVEWNEKINLTAI
                     TDKEEVYLKHFYDSIAPILQGLIPNETIKLLDIGAGAGFPSLPMKILYPELDVTIIDS
                     LNKRINFLQLLAQELDLNGVHFYHGRAEDFAQDKNFRAQYDFVTARAVARMQVLSELT
                     IPYLKVGGKLLALKASNAPEELLEAKNALNLLFSKVEDNLSYALPNRDPRYITVVEKK
                     KETPNKYPRKAGMPNKRPL"
     gene            12357..12917
                     /locus_tag="VQ540_000019"
     CDS             12357..12917
                     /locus_tag="VQ540_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LemA family protein"
                     /protein_id="HET2543906.1"
                     /translation="MTWIILGVIALIVIFVIVSYNGLVKNRMQTKEAWSQIDVQLKRR
                     NDLLPNLIETVKGYAKYEGSTLEKVAELRNQVAAATSPAEAMKASDALTRQVSGIFAV
                     AESYPDLKASANFVKLQEELTNTENKISYSRQLYNSVVSNYNVKLETFPSNIIAGMFG
                     FKAADFLQTSEEEKSVPKVDFSGLGD"
     gene            12919..13818
                     /gene="htpX"
                     /locus_tag="VQ540_000020"
     CDS             12919..13818
                     /gene="htpX"
                     /locus_tag="VQ540_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease HtpX"
                     /protein_id="HET2543907.1"
                     /translation="MLFDQIASNKRKTWILLLVFFLLLALVGYAVGYLFIRSGLGGLV
                     IALIIGFIYALSMIFQSTEIVMSMNGAREVDEQTAPDLYHVVEDMALVAQIPMPRVFI
                     IDDPALNAFATGSNPQNAAVAATSGLLAIMNREELEAVMGHEVSHIRNYDIRISTIAV
                     ALASAITMLSSMAGRMMWWGGAGRRRSDDDRDGNGLEIIMLVVSLLAIVLAPLAATLV
                     QLAISRQREFLADASSVELTRNPQGMINALDKLDNSKPMSRHVDDASSALYINDPKKG
                     GGFQKLFYTHPPISERIERLKQM"
     gene            complement(13862..15421)
                     /locus_tag="VQ540_000021"
     CDS             complement(13862..15421)
                     /locus_tag="VQ540_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HET2543908.1"
                     /translation="MHYRHSRKGNSMIKINHLTITQNKDLRDLVSDLSMTIQDGEKVA
                     IIGEEGNGKSTLLKTLMGEDLSDFTIKGDIQSDYQSLAYIPQKVPEDLKKKTLHDYFF
                     LDSIDLDYSILYRLAEELHFDSNRFASDQEIGNLSGGEALKIQLIHELAKPFEILFLD
                     EPSNDLDLETVDWLKGQIQKTRQTVIFISHDEDFLSETADTIVHLRLVKHRKEAETLV
                     EHLDYDSYSEQRKANFAKQSQQAANNQRAYDKTMEKHRRVKQNVETALRATKDSTAGR
                     LLAKKMKTVLSQEKRYEKTAQSMTQKPLEEEQIQLFFSDIQPLPASKVLVQLEKENLS
                     IDDRVLAQELQLTVRGQEKIGIIGPNGVGKSTLLAKLQQLLNDKREISLGFMPQDYHK
                     KLQLDLSSIAYISKTGEKEELQKIQSHLASLNFSYPEMQHQIRSLSGGQQGKLLLLDL
                     VLRKPNFLLLDEPTRNFSPTSQPQIRKLFATYPGGLITVSHDRRFLKEVCSIIYRMTE
                     HGLKLVNLEDL"
     gene            complement(15660..15977)
                     /locus_tag="VQ540_000022"
     CDS             complement(15660..15977)
                     /locus_tag="VQ540_000022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000389556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
                     /protein_id="HET2543909.1"
                     /translation="MEDKKLIQLLSKLNKSYQNCKQGTADDIRLQELLNTTMQELKKT
                     EKLNNSILIDLEKFYQPTSPLIGLGSLKLNDQARTAWRNYDKIHYEHVKHVLSLYGPV
                     FGF"
     gene            16156..16698
                     /locus_tag="VQ540_000023"
     CDS             16156..16698
                     /locus_tag="VQ540_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HET2543910.1"
                     /translation="MKLNIQEIRKQSEGLNFEQTLDLVDDLRARNQEILDVKDILAVG
                     KVQYEDRMYFLDYQLSYTIVLASSRSMEPVELVESYPVTEVFMEGATNQLDQEVLDDD
                     LVLPIENGELDLAESVSDNILLNIPIKVLTAEEEAGQGFISGNDWQIMTEEEYQAQQA
                     VKKEENSPFAGLQGLFDGDE"
     gene            16698..17327
                     /gene="nth"
                     /locus_tag="VQ540_000024"
     CDS             16698..17327
                     /gene="nth"
                     /locus_tag="VQ540_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000244461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HET2543911.1"
                     /translation="MVLSKKRARKVLEEIIALFPDAKPSLDFTNHFELLVAVMLSAQT
                     TDAAVNKATPGLFVAFPTPQAMSVATESEIASHISRLGLYRNKAKFLKKCAQQLLDDF
                     DGQVPQTREELESLAGVGRKTANVVMSVGFGIPAFAVDTHVERICKHHDIVKKSATPL
                     EVEKRVMDILPPEQWLAAHQAMIYFGRAICHPKNPECDQYPQLYDFSNL"
     gene            17538..18059
                     /gene="pyrR"
                     /locus_tag="VQ540_000025"
     CDS             17538..18059
                     /gene="pyrR"
                     /locus_tag="VQ540_000025"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HET2543912.1"
                     /translation="MKTKEVVDELTVKRAITRITYEIIERNKDLNKIVLAGIKTRGVF
                     IAHRIQERLKQLENLSVPVVELDTKPFRDDVKSGEDTSLVSVDVTDREVILVDDVLYT
                     GRTIRAAIDNIVGHGRPARVSLAVLVDRGHRELPIRPDYVGKNIPTSRSEEIIVEMTE
                     LDDQDRVLITEEA"
     gene            18078..19001
                     /locus_tag="VQ540_000026"
     CDS             18078..19001
                     /locus_tag="VQ540_000026"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001293822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HET2543913.1"
                     /translation="MSENQQALNHVVSMEDLTVDQVMKLIKRGIEFKNGAQLPYEDHP
                     IVSNLFFEDSTRTHKSFEVAEIKLGLERLDFDVKTSSVNKGETLYDTILTLSALGVDV
                     CVIRHPEVDYYRELIASPTITTSIINGGDGSGQHPSQSLLDLMTIYEEFGHFEGLKVA
                     IAGDLDHSRVAKSNMQILKRLGAELFFAGPEEWRSQEFADYGKFVTIDEIIDQVDVMM
                     FLRVQHERHDSGAVFSKEDYHAQHGLTQERYDRLKETAILMHPAPINRDVEIADHLVE
                     APKSRIVQQMTNGVFVRMAILESVLASRNAN"
     gene            19051..20130
                     /gene="carA"
                     /locus_tag="VQ540_000027"
     CDS             19051..20130
                     /gene="carA"
                     /locus_tag="VQ540_000027"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HET2543914.1"
                     /translation="MTKRILVLEDGTVFEGKAFGADIDVTGEIVFNTGMTGYQESITD
                     QSYNGQILTFTYPLVGNYGINRDDYESIIPTCKGVVVFEEARRASNWRNQMTLDEFLK
                     AKKIPGISGIDTRALTKIIRKHGTMRATLTHVGDSMDHVTDQLQATVLPTDNIKQVST
                     KTSYPAPGVGLSVVLVDFGLKHSILRELSKRNCNVTVVPYSTTAEEILHLNPDGVMLS
                     NGPGNPEDVPQALDMIRGVQGKIPIFGICMGHQLFAMANGAKTYKMKFGHRGFNHAVR
                     EIATGRVDFTSQNHGYAVSREDLPEHLIITHEEINDKSVEGVRHRYQPAFSVQYHPDA
                     APGPHDASYLFDEFIEMMEVFKQSN"
     gene            20442..23618
                     /gene="carB"
                     /locus_tag="VQ540_000028"
     CDS             20442..23618
                     /gene="carB"
                     /locus_tag="VQ540_000028"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HET2543915.1"
                     /translation="MPKRTDIQKIMVIGSGPIIIGQAAEFDYAGTQACLSLKEEGYEV
                     VLVNSNPATIMTDKEIADKVYIEPITLEFVTRILRKERPDALLPTLGGQTGLNMAMEL
                     SKNGILDELGVELLGTKLSAIDQAEDRDLFKQLMEELEQPIPESEIVNTVEEAVAFAA
                     TIGYPVIVRPAFTLGGTGGGMCANEKELREITENGLKLSPVTQCLIERSIAGFKEIEY
                     EVMRDSADNALVVCNMENFDPVGIHTGDSIVFAPAQTMSDYENQMLRDASLSIIRALK
                     IEGGCNVQLALDPNSFKYYVIEVNPRVSRSSALASKATGYPIAKLAAKIAVGLTLDEV
                     INPVTGSTYAMFEPALDYVVAKIPRFPFDKFEKGERRLGTQMKATGEVMAIGRNIEES
                     LLKACRSLEIGVHHNEIPELAAVSDDALIEKVVKAQDDRLFYVSEAIRRGYTPEEIAE
                     LTKIDIFYLDKLLHIFEIEQELGAHPQDLEVLKTAKLNGFSDRKIAELWGTTDDQVRQ
                     LRLENKIVPVYKMVDTCAAEFDSETPYFYSTYGWENESIRSDKESVLVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQAAGYEAIIMNSNPETVSTDFSVSDKLYFEPLTFEDVMNVIDL
                     EQPKGVIVQFGGQTAINLAEPLAKAGVTILGTQVADLDRAEDRDLFEQALKELDIPQP
                     PGQTATNEEEAALAARKIGFPVLVRPSYVLGGRAMEIVENEEDLRSYMRTAVKASPDH
                     PVLVDSYIVGQECEVDAISDGKNVLIPGIMEHIERAGVHSGDSMAVYPPQTLSQKVQE
                     TIADYTKRLAIGLHCLGMMNIQFVIKDEKVYVIEVNPRASRTVPFLSKVTNIPMAQVA
                     TKLILGQSLSELGYQNGLYPESTRVHIKAPVFSFTKLAKVDSLLGPEMKSTGEVMGSD
                     ATLEKALYKAFEASYLHLPTFGNVVFTIADDAKEEALNLARRFQNIGYGILATEGTAA
                     FFASHGLQAQPVGKIGDDDKDIPSFVRKGRIQAIINTVGTKRTADEDGEQIRRSAIEH
                     GVPLFTALDTANAMLKVLESRSFVTEAI"
     gene            complement(23893..24702)
                     /locus_tag="VQ540_000029"
     CDS             complement(23893..24702)
                     /locus_tag="VQ540_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HET2543916.1"
                     /translation="MQYLEKKEIKEIQLALLDYIDETCKKHDIPYFLSYGTMLGAIRH
                     KGMIPWDDDIDISLYREDYERLLKIIEEENHPRYKVLSYDTSSWYFHNFASILDTSTV
                     IEDHVKYKRHDTSLFIDVFPIDQFTDLSIVDKSYKYVALRQLAYIKKSRAVHGDSKLK
                     DFLRLCSWYALRFVNPRYFYKKIDQLVKNAVTNIPQYEGGVGIGKEGMKEIFPVDTFK
                     ELILTEFEGRMLPVPKKYDQFLTQMYGDYMTPPSKEMQEWYSHSIKAYRKN"
     gene            complement(24704..25507)
                     /locus_tag="VQ540_000030"
     CDS             complement(24704..25507)
                     /locus_tag="VQ540_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HET2543917.1"
                     /translation="MKQLTVEDAKQIELEILNYIDTLCKKHNINYIINYGTLIGAVRH
                     EGFIPWDDDIDLSMPREDYQRFINIFQKEKSKYKLLSLETDKNYFNNFIKITDSTTKI
                     IDTRNTKTYESGIFIDIFPMDRFDDPKVIDTCYKLESFKLLSFSKHKNIVYKDSLLKD
                     WIRTAFWLLLRLVSPRYFANKIEKEIQKYSRENGQYMAFIPSKFKEKEVFPSATFDKT
                     IDLPFENLSLPAPEKFDTILTQFYGDYMTLPPEEKRFYSHEFHAYKLED"
     gene            complement(25517..27004)
                     /gene="tacF"
                     /locus_tag="VQ540_000031"
     CDS             complement(25517..27004)
                     /gene="tacF"
                     /locus_tag="VQ540_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV teichoic acid flippase TacF"
                     /protein_id="HET2543918.1"
                     /translation="MKSIKLNALSYMGIRVLNIIFPILTGTYVARVLDRTDYGYFNSV
                     DTILSFFLPFATYGVYNYGLRAISNVKDNKKDLNRTFSSLFYLCIACTILTTAVYILA
                     YPLFFTDNPIVKKVYLVMGIQLIAQIFSIEWVNEALENYSFLFYKTAFIRILMLVSIF
                     LFVKNEHDIVVYTLVMSLSTLINYLISYFWIKRDIKLVKIHLSDFKPLFLPLTAMLVF
                     ANANMLFTFLDRLFLVKTGIDVNVSYYTIAQRIVTVIAGVVTGAIGVSVPRLSYYLGK
                     GDKEAYVSLVNRGSRIFNFFIIPLSFGLMVLGPNAILLYGSEKYIGGDILTSLFAFRT
                     IILALDTILGSQILFTNGYEKRITVYTVFAGLLNLGLNSLLFFNHIVAPEYYLLTTML
                     SEASLLVFYIIFIHRKQLIHLGHIFSYTVRYSLFSLSFVAIYFLINFVYPVDMVINLP
                     FLINTGLIVLLSAISYISLLVFTKDSIFYEFLNHVLALKNKFKKS"
     gene            27340..28047
                     /locus_tag="VQ540_000032"
     CDS             27340..28047
                     /locus_tag="VQ540_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="HET2543919.1"
                     /translation="MIYAGILAGGTGTRMGISNLPKQFLELGDRPILIHTIEKFVLEP
                     SIEKIVVGVHGDWVSHAEDLVDKYLPLYKERIIITKGGADRNTSIKKIIEAIDAYRPL
                     TPEDIVVTHDSVRPFITLRMIQDSIQLAQNHDAVDTVVEAVDTIVESTNGQFITDIPN
                     RAHLYQGQTPQTFRCKDFMDLYGSLSDEEKEILTDACKIFVIKGKDVALAKGEYSNLK
                     ITTVTDLKIAKSMIEKD"
     gene            28052..29074
                     /locus_tag="VQ540_000033"
     CDS             28052..29074
                     /locus_tag="VQ540_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HET2543920.1"
                     /translation="MINQIYQLTKPKFINVKYQEEAIDQENHILIRPNYMAVCHADQR
                     YYQGKRDPKILNKKLPMAMIHESCGTVISDPTGTYEVGQKVVMIPNQSPMQSDEEFYE
                     NYMTGTHFLSSGFDGFMREFVSLPKDRVVAYDAIEDTVAAITEFVSVGMHAMNRLLTL
                     AHSKRERIAVIGDGSLAFVVANIINYTLPEAEIVVIGRHWEKLELFSFAKECYITDNI
                     PEELAFDHAFECCGGDGTGPAINDLIRYIRPQGTILMMGVSEYKVNLNTRDALEKGLI
                     LVGSSRSGRIDFKNAIQMMEVKKFANRLKNILYLEEPVREIKDIHRVFATDLNTAFKT
                     VFKWEV"
     gene            29091..29960
                     /gene="licA"
                     /locus_tag="VQ540_000034"
     CDS             29091..29960
                     /gene="licA"
                     /locus_tag="VQ540_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline kinase LicA"
                     /protein_id="HET2543921.1"
                     /translation="MEKIIKEKISSLLSQEEEVLSVEQLGGMTNQNYLAKTTNKQYIV
                     KFFGKGTEKLINRQDEKYNLELLKDLGLDVKNYLFDIEAGIKVNEYIESAITLDSTSI
                     KTKFDKIAPILQTIHTSAKELRGEFAPFEEIKKYESLIEEQIPYANYESVRNAVFSLE
                     KRLADLGVDRKSCHIDLVPENFIESPQGRLYLIDWEYSSMNDPMWDLAALFLESEFTS
                     QEEETFLSHYESDQTPVSHEKIAIYKILQDTIWSLWTVYKEEQGEDFGDYGVNRYQRA
                     VKGLASYGGSDEK"
     gene            29950..30828
                     /locus_tag="VQ540_000035"
     CDS             29950..30828
                     /locus_tag="VQ540_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HET2543922.1"
                     /translation="MKSKNGVPFGLLSGIFWGLGLTVSAYIFSIFTDLSPFVVAAAHD
                     FLSIFILLAFLLVKEGKVRLSIFLNIRNVSVIIGALLAGPIGMQANLYAVKYIGSSLA
                     SSVSAIYPAISVLLAFFFLKHKISKNTVFGIVLIIGGIIAQTYKVEQVNSFYIGILCA
                     LVCAIAWGSESVLSSFAMESELSEIEALLIRQVTSFLSYLVIVLFSHQSFTAVANGQL
                     LGLMIVFAAFDMISYLAYYIAINRLQPAKATGLNVSYVVWTVLFAVVFLGAPLDMLTI
                     MTSLVVIAGVYIIIKE"
     gene            30840..31529
                     /locus_tag="VQ540_000036"
     CDS             30840..31529
                     /locus_tag="VQ540_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NTP transferase domain-containing protein"
                     /protein_id="HET2543923.1"
                     /translation="MKAIILAAGLGTRLRPMTENTPKALVQVNQKPLIEYQIEFLKEK
                     GINDIIIIVGYLKEQFDYLKEKYGVRLVFNDKYADYNNFYSLYLVKEELANSYVIDAD
                     NYLFKNMFRNDLTRSTYFSVYREDCTNEWFLVYGDDYKVQNIIVDSKAGRILSGVSFW
                     DAPTAEKIVSFIDKAYASGEFVDLYWDNMVKDNIKELDVYVEELEGNSIYEIDSVQDY
                     HKLEEILKNEN"
     gene            31627..32475
                     /gene="dprA"
                     /locus_tag="VQ540_000037"
     CDS             31627..32475
                     /gene="dprA"
                     /locus_tag="VQ540_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HET2543924.1"
                     /translation="MKITNYEIYKLKKSGLTNQQILKVLEYGENVDQELLLGDIADIS
                     GCRNPAVFMERYFQIDDAHLSKEFQKFPSFSILDDCYPWDLSEIYDAPVLLFYKGNLD
                     LLKFPKVAVVGSRACSKQGAKSVEKVIQGLENELVIVSGLAKGIDTAAHMAALQNGGK
                     TIAVIGTGLDVFYPKANKRLQDYIGNDHLVLSEYGPGEQPLKFHFPARNRIIAGLCRG
                     VIVAEAKMRSGSLITCERAMEEGRDVFAIPGSILDGLSDGCHHLIQEGAKLVTSGQDV
                     LAEFEF"
     gene            33359..34402
                     /locus_tag="VQ540_000038"
     CDS             33359..34402
                     /locus_tag="VQ540_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00341 family protein"
                     /protein_id="HET2543925.1"
                     /translation="MTNNKLYSLIEFRNKIYEELELSRSDLAILLCAMLIASIGLNMD
                     STPVIIGAMLISPLMTPILGVGLSLAIFDFKLLRKSFKILAIQILASLIASTLYFYLS
                     PISYASSEIVARTSPTIWDVLIAFVGGIAGIIGARKKETNNIVPGVAIATALMPPLCT
                     VGYAIASANLKFIIGSSYLFLINCSFIVIATYIGVRLMMVKKHYFKDNEEDSKMRRIL
                     LLVAVLLMIPSFISATTLVRETLKKESLKKFISEQFQGHNILKKTYSKKTHTLKLTIS
                     GNYLTEEELDMISSKRGDYGLSDVSVQVSQLSDSEQLSKEELVEYFFQYIKDKEAKEK
                     EKANKFYTESEEQ"
     gene            34569..36656
                     /gene="topA"
                     /locus_tag="VQ540_000039"
     CDS             34569..36656
                     /gene="topA"
                     /locus_tag="VQ540_000039"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HET2543926.1"
                     /translation="MATATKKKKSTVKKNLVIVESPAKAKTIEKYLGRNYKVLASVGH
                     IRDLKKSSMSVDIENNYEPQYINIRGKGPLINDLKKEAKKANKVFLASDPDREGEAIS
                     WHLAHILNLDENDANRVVFNEITKDAVKNAFKEPRKIDMDLVDAQQARRILDRLVGYS
                     ISPILWKKVKKGLSAGRVQSIALKLIIDRENEINAFQPEEYWTVDAVFKKGTKQFHAS
                     FYGVDGKKMKLTSNDEVKEVLSRLTSKDFSVDQVDKKERKRNAPLPYTTSSMQMDAAN
                     KINFRTRKTMMVAQQLYEGINIGSGVQGLITYMRTDSTRISPVAQNEAASFITDRFGS
                     KYSKHGSKVKNASGAQDAHEAIRPSSVFNTPESIAKYLDKDQLKLYTLIWNRFVASQM
                     TAAVFDTMAVKLSQNGVQFAANGSQVKFDGYLAIYNDSDKNKMLPDMVVGDVVKQVNS
                     KPEQHFTQPPARYSEATLIKTLEENGVGRPSTYAPTIETIQKRYYVRLAAKRFEPTEL
                     GEIVNKLIVEYFPDIVNVTFTAEMEGKLDDVEVGKEQWRRVIDAFYKPFSKEVAKAEE
                     EMEKIQIKDEPAGFDCEVCGSPMVIKLGRFGKFYACSNFPDCRHTQAIVKEIGVECPS
                     CHQGQIIERKTKRNRLFYGCNRYPECEFTSWDKPVGRDCPKCGNFLMEKKVRGGGKQV
                     VCSKGDYEEEKIK"
     gene            36877..37236
                     /locus_tag="VQ540_000040"
     CDS             36877..37236
                     /locus_tag="VQ540_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaN family protein"
                     /protein_id="HET2543927.1"
                     /translation="MRIIYLIIGFLSLTLAIVGVVLPLLPTTPFLLLSIACFSRSSKR
                     FEDWLYHTKLYQAYVADFRETKSIARERKKKIIVSIYVLMGISIYFAPLLPVKIGLGA
                     LTIFITYYLFKVIPDKE"
     gene            37329..37961
                     /locus_tag="VQ540_000041"
     CDS             37329..37961
                     /locus_tag="VQ540_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HET2543928.1"
                     /translation="MIYEFCAENVTLLEKAMQAGARRIELCDNLAVGGTTPSYGVTKA
                     AVELAANYDTTIMTMIRPRGGDFVYNDLEIAIMLEDIRLTAQAGSQGVVFGALTADKK
                     LDKPNLEKLIAASKGMEIVFHMAFDELSDEDQPEAIDWLSQAGVTRILTRAGVSGDSL
                     EKRFVHYHRILEYAKGKIEILPGGGIDLENRQTFIDQVGVTQLHGTKVVF"
     gene            38005..38661
                     /locus_tag="VQ540_000042"
     CDS             38005..38661
                     /locus_tag="VQ540_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HET2543929.1"
                     /translation="MFEIFKSYQFNQEKAHDYGFIENSEVWTYSCQILQGDFVMTVSI
                     TADNVNFQVFDQETGDLYPHVYMESMRGSFVGNVREACLEILYQIRKACFDVQDFICH
                     QTKRIMTQVQEKYGNQLEYLWEKSPDTAVLRHEGNQKWYAVLMKISWNKLEKGREGQV
                     EAVNLKHDQVANLLSQKGIYPAFHMSKRYWISVSLDDTLSDEEVLELIEKSWNLTSKK
                     "
     gene            38680..39774
                     /locus_tag="VQ540_000043"
     CDS             38680..39774
                     /locus_tag="VQ540_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001010962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-isopropylmalate synthase"
                     /protein_id="HET2543930.1"
                     /translation="MNFQLAKYSLLKRFLENIGFTTLEEYGAIFKYLIENVKTDRQII
                     YSPHCHDDLGMAVANSLAAVKNGAGRVEGTINGIRERAENAALEEIAVALNIRQDYYQ
                     VETSIVLNETINTSEMVSRFSGIPVPKNKAVVGGNTFSHESGIHQDGVLKNPLTYEII
                     TPELVGVKILLGKLSGRHAFVEKLRELALDFTEEDIKPLFAKFKALVDKKQEITDADI
                     RALVAGTMVENPEGFHFDDLQLQTHADNDIEALVSLANMDGEKVEFNATGQGSVEAIF
                     NAIDKFFNQSVRLVSYTIDAVTDGIDTQDRVLVTVENRDTETIFNAAGLDFDVLKASA
                     IVYINANTFVQKENAGEMGRSVSYHDMPSV"
     gene            39786..40823
                     /gene="leuB"
                     /locus_tag="VQ540_000044"
                     /pseudo
     CDS             39786..40823
                     /gene="leuB"
                     /locus_tag="VQ540_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399454.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydrogenase"
     gene            40820..41089
                     /locus_tag="VQ540_000045"
     CDS             40820..41089
                     /locus_tag="VQ540_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HET2543931.1"
                     /translation="MKLDEKITLVLLIWNVIIFLIYGIDKSKARRRVWRIPEKILLIL
                     AFTFGGFGAWLAGIIFHHKTRKWYFKIVWFLGMVTTLVALYFIWR"
     gene            41093..41452
                     /gene="leuD"
                     /locus_tag="VQ540_000046"
     CDS             41093..41452
                     /gene="leuD"
                     /locus_tag="VQ540_000046"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase small subunit"
                     /protein_id="HET2543932.1"
                     /translation="MAGSSREYAAWALADYGFKVVIAGSFGDIHYNNELNNGMLPIVQ
                     PREVREKLAQLKPTDQVTVDLEQQKIISPVEEFTFEIDSEWKHKLLNSLDDIGITLQY
                     EELIAAYEKQRPAYWQD"
     gene            41614..42182
                     /locus_tag="VQ540_000047"
                     /pseudo
     CDS             41614..42182
                     /locus_tag="VQ540_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019771122.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="translation factor (SUA5)"
     gene            42276..42341
                     /locus_tag="VQ540_000048"
                     /pseudo
     CDS             42276..42341
                     /locus_tag="VQ540_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849983.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="translation factor (SUA5)"
     gene            42504..44435
                     /locus_tag="VQ540_000049"
     CDS             42504..44435
                     /locus_tag="VQ540_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrB family protein"
                     /protein_id="HET2543933.1"
                     /translation="MNKRKVSLEDFYKWYSLNKEELLNKATVGEKFNDKLKEEFLQEW
                     PLDRILTMSIDEYVIGKGQQNKSLCYALEKGKYKNLFLGISGGSASKFGIYWNKKTNK
                     YKDQANNEISELDQRFSKLKSDLYEIIKEGIRFNFENPIFDMKRSTNEFIGRSAMVTK
                     LLCIYTEGDPFFGVNINSQKEFWNHFVSQTNQGGPYLQNHKIIELMSKTYPELEPSKL
                     GTMLFEYSKLFMENKEDNSTMDSSNNFRHQLTQSLLKSPNLILRGAPGTGKTYLAKEI
                     AKELTDGNEDQIGFVQFHPSYDYTDFVEGLRPVSNGDGAIEFRLQDGIFKDFCQKAKE
                     TQLIGGQDNFDEAWDSYLEYINVAEEKEYITKTSYLSVNSRQNLSVNYDSGVPGWSLP
                     SKYVYELYKDKNYNKQEYYKSGGKTVLETLRKRFGLKDYVSPTEIDTDKKFVFIIDEI
                     NRGEISKIFGELFFSIDPGYRGEKGSVSTQYANLHETDEKFYIPENVYIIGTMNDIDR
                     SVDTFDFAMRRRFRFVEVTAEGQVGMLDKELNIHAEEAKIRLRNLNAAIENVQELNSH
                     YHIGPSYFLKLKDVDFDYELLWSDYIKPLLEDYLRGSYDEVETLETLKKAFELTNNEQ
                     KDQAVADDNESDENDDADY"
     gene            44422..45774
                     /locus_tag="VQ540_000050"
     CDS             44422..45774
                     /locus_tag="VQ540_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001223073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrC family protein"
                     /protein_id="HET2543934.1"
                     /translation="MRITDNQHKIIKEKFVEEYPKLSNLLLDRTLESLSQDERIFIFP
                     NDLTHTPDLDKKQKILETINQEIKTGNVIGFLGYGQERLTISSRFSDESNDHFLHYLL
                     NKVLHINLTSLDVALSREERLYQLLMYLFPKYLQAAIRKGLYKEYHRFSHNDSHVKGV
                     IDVRNHLKKNLPFTGNIAYTTREFTYDNPLMQLVRHTIEYIKNQKSIGQGVLDNLSTS
                     RENVSEIVRVTPSYKLADRAKIIRGNQSKPIRHAYFHEYRNLQELCLMILNQEKHGLG
                     YQDQKIYGILFDVAWLWEEYVYTLLPKGFVHPRNKDKTDGISVFSVGKRKVYPDFYDR
                     ERKIVLDAKYKKLELTEKGINREDLFQLISYSYILKAEKAGLVFPSKDKVIDNEMGNL
                     AGYGALLKKWSIQIPQKSSSYSAFCKMMENSDYSAFCKMMENSEENFKAIIDEEVGRK
                     "
     gene            45949..46935
                     /locus_tag="VQ540_000051"
     CDS             45949..46935
                     /locus_tag="VQ540_000051"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HET2543935.1"
                     /translation="MLNEFPIFDYEDIQLIPNKCVIKSRAEADTSVTLGNHTFKLPVV
                     PANMQTILDENVAEQLAKGGYFYIMHRFDEAGRIPFIKQMHDQGLIASISVGVKDYEY
                     DFVSQLKTDAPEYITIDIAHGHADSVISMIQHIKKELPDTFVIAGNVGTPEAVRELEN
                     AGADATKVGIGPGKVCITKVKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIA
                     KSIRFGASMIMIGSLFAGHIESPGKTIEVDGEQFKEYYGSASQYQKGAYKNVEGKRIL
                     LPAKGHLQDTLTEMEQDLQSAISYAGGRQVADLKHVDYVIVKNSIWNGDASH"
     gene            46999..47070
                     /locus_tag="VQ540_000052"
     tRNA            46999..47070
                     /locus_tag="VQ540_000052"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:47032..47034,aa:Arg,seq:ccg)
     gene            47253..47951
                     /locus_tag="VQ540_000053"
     CDS             47253..47951
                     /locus_tag="VQ540_000053"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HET2543936.1"
                     /translation="MKELQTVLKNHFAIEFADKNLLETAFTHTSYANEHRLLKISHNE
                     RLEFLGDAVLQLLISEYLYKKYPKKPEGDLSKLRAMIVREESLAGFARDCQFDQFIKL
                     GKGEEKSGGRNRDTILGDAFEAFLGALLLDKDVAKVKEFIYQVMIPKVEAGEFEMITD
                     YKTHLQELLQVNGDVAIRYQVISETGPAHDKVFDVEVLVEGKSIGQGQGRSKKLAEQE
                     AAKNAVEKGLDSCI"
     gene            47942..51481
                     /gene="smc"
                     /locus_tag="VQ540_000054"
     CDS             47942..51481
                     /gene="smc"
                     /locus_tag="VQ540_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HET2543937.1"
                     /translation="MYLKEIEIQGFKSFADKTKVVFDQGVTAVVGPNGSGKSNITESL
                     RWALGESSVKSLRGGKMPDVIFAGTESRKPLNYASVVVTLDNHDGFIKDAGQEIRVER
                     HIYRSGDSEYKIDGKKVRLRDIHDLFLDTGLGRDSFSIISQGKVEEIFNSKSEERRAI
                     FEEAAGVLKYKTRRKETESKLQQTQDNLDRLEDIIYELDNQIKPLEKQAENARKFLDL
                     EGQRKAIYLDVLVAQIKENKAELESTEEELAQVQELLMSYYQKREKLEEENQTLKKQR
                     QDLQAEMAKDQGSLMDLTSLISDLERKLALSKLESEQVALNQQEAQARLAALEDKRNS
                     LSKEKSDKESSLALLEGNLVQNNQKLNRLEAELLAFSDDPDQMIELLRERFVALLQEE
                     ADVSNQLTRIENELENSRQLSQKQADQLEKLKEQLAIAKEKASQQKEELETAKEQVQK
                     LLADYQAIAKEQEEQKTSYQAQQSQLFDRLDNLKNKQARAQSLENILRNHSNFYAGVK
                     SVLQEKDRLGGIIGAVSEHLTFDMHYQTALEIALGASSQHIIVEDEESATKAIDFLKR
                     NRAGRATFLPLTTIKARTISSQNQDAITVSPGFLGMADELVTFDTRLEAIFKNLLATT
                     AIFDAVEHARAAARQVRYQVRMVTLDGTELRTGGSYAGGANRQNNSIFIKPELEQLQK
                     EIAADEASLRSEEAALKTLQDQMATLTERLEVIKSQGEQARIQEQGLSLAYQQTSQQV
                     EELETLWKLQEEEIDRLSEGDWQADKEKCQDRLAAIASDKQNLEAEIEEIKSNKNAIQ
                     ERYQNLQEELAQARLLKTELQGQKRYEVADIERLGKELDNLDFEQEEIQRLLQEKVDN
                     LEKVDTELLSQQAEEAKTQKTNLQQGLIRKQFELDDIEGQLDDIASHLDQARQQNEEW
                     IRKQTRAEAKKEKVSERLRYLQSQLTDQYQISYTEALEKAHELENLNLAEQEVQDLEK
                     AIRSLGPVNIEAIDQYEEVHNRLDFLNSQRDDILSAKNLLLETITEMNDEVKDRFKST
                     FEAIRESFKVTFKQMFGGGQADLILTEGDLLTAGVEISVQPPGKKIQSLNLMSGGEKA
                     LSALALLFSIIRVKTIPFVILDEVEAALDEANVKRFGDYLNRFDKDSQFIVVTHRKGT
                     MAAADSIYGVTMQESGVSKIVSVKLKDLESIEG"
     gene            51478..52272
                     /locus_tag="VQ540_000055"
     CDS             51478..52272
                     /locus_tag="VQ540_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000153012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HET2543938.1"
                     /translation="MTIKLVATDMDGTFLDGNGRFDMDRLKSLLASYKEKGIYFAVAS
                     GRGFLSLEKLFAGVRDDIIFIAENGSLVEYQGQDLYEATMSRDFYLATFEKLKTSPYV
                     DINKLLLTGKKGSYVLDTVDETYLKVSQHYNENIQKVASLEDITDDIFKFTTNFTEET
                     LEAGETWVNDNVPGVKAMTTGFESIDIVLDYVDKGVAIVELAKKLGITMDQVMAFGDN
                     LNDLHMMQVVGHPVAPENARPEILELAKTVIGHHKDQSVIAYMEGL"
     gene            52272..53090
                     /locus_tag="VQ540_000056"
     CDS             52272..53090
                     /locus_tag="VQ540_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HET2543939.1"
                     /translation="MADIKLIALDLDGTLLTTDKRLTDRTKATLKAASDRGIKVVLTT
                     GRPLKAMDFFLHELGTDGHEDEYTITFNGGLVQKNTGEILDKTVFSYDDVARLYEETE
                     KLSLPLDAISEGTVYQIQSDQESLYAKFNPALTFVPVDFEDLSSQMTYNKCVTAFAQE
                     PLDAAIQKISPELFDQYEIFKSREMLLEWSPKNVHKATGLAKLISHLGIDQSQVMACG
                     DEANDLSMIEWAGLGVAMQNAVPEVKAAANVVTPMTNDEEAVAWAIEEYVLKEN"
     gene            53094..54314
                     /gene="ftsY"
                     /locus_tag="VQ540_000057"
     CDS             53094..54314
                     /gene="ftsY"
                     /locus_tag="VQ540_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HET2543940.1"
                     /translation="MGLFDRLFGKKEEPKIEEVVKEALENLDLSEDVDPTFTEVEEVS
                     QEEAVLEESQDSEPAVGVSQEEIEELPEEEKLEHEGTIEENNSEVLEAERPQTEETVQ
                     EKYDRSLKKTRTGFGARLNAFFANFRSVDEEFFEELEELLIMSDVGVQVASNLTEELR
                     YEAKLENAKKPDALRRVIIEKLVELYEKDGSYDESIHFQDNLTVMLFVGVNGVGKTTS
                     IGKLAHRYKRAGKKVMLVAADTFRAGAVAQLAEWGRRVDVPVVTGPEKADPASVVFDG
                     MERAVAEGIDILMIDTAGRLQNKDNLMTELEKIGRIIKRVVPEAPHETFLALDASTGQ
                     NALVQAKEFSKITPLTGIVLTKIDGTARGGVVLAIREELNIPVKLIGFGEKIDDIGEF
                     NSENFMKGLLEGLI"
     gene            complement(54360..55847)
                     /locus_tag="VQ540_000058"
     CDS             complement(54360..55847)
                     /locus_tag="VQ540_000058"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HET2543941.1"
                     /translation="MSSKVIVTIFGASGDLAKRKLYPSLFRLYQSGNLSKHFAVIGTA
                     RRPWSKEYFESVVVESILDLADSTEQAQEFASHFYYQSHDVNDSEHYIALRQLQAELN
                     EKYQAEHNKLFFLSMAPQFFGTIAKHLKSENIVDGKGFERLIVEKPFGTDYATASKLN
                     DELLATFDEEQIFRIDHYLGKEMIQSIFAVRFANLIFENVWNKDFIDNVQITFAERLG
                     VEERGGYYDQSGALRDMVQNHTLQLLSLLAMDKPAIFTKDEIRAEKIKVFKNLYHPTD
                     EELKEHFIRGQYRSGKIDGMKYISYRSEPNVNPESTTETFTSGAFFVDSDRFRSVPFF
                     FRTGKRLTEKGTHVNIVFKQMDSIFGEPLAPNILTIYIQPTEGFSLSLNGKQVGEEFN
                     LAPNSLDYRTDATATGASPEPYEKLIYDVLNNNSTNFSHWDEVGASWKLIDRIEELWA
                     ENGAPLHDYKAGSMGPQASFDLLEKFGAKWTWQPDIAYRQDGRFE"
     gene            complement(55996..56736)
                     /locus_tag="VQ540_000059"
     CDS             complement(55996..56736)
                     /locus_tag="VQ540_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HET2543942.1"
                     /translation="MAKLKIDVNDLHKHYGKNEVLKGITTKFYEGDVVCIIGPSGSGK
                     STFLRSLNLLEEVTSGHITVNGYDLTEKTTNVDHVRENIGMVFQHFNLFPHMSVLDNI
                     TFAPIEHKLMTKEEAEELGMELLEKVGLADKANANPDNLSGGQKQRVAIARGLAMNPD
                     IMLFDEPTSALDPEMVGDVLNVMKELAEQGMTMIIVTHEMGFARQVANRVIFTADGEF
                     LEDGTPDQIFDNPQHPRLKEFLDKVLNV"
     gene            complement(56736..58901)
                     /locus_tag="VQ540_000060"
     CDS             complement(56736..58901)
                     /locus_tag="VQ540_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HET2543943.1"
                     /translation="MKKKFLAFLLILFPIFSLGIAKAETIKIVSDTAYAPFEFKDSDQ
                     TYKGIDVDIINKVAEIKGWNIQMSYPGFDAAVNAVQAGQADAIMAGMTKTKEREKVFT
                     MSDTYYDTKVVIATTKSHKISKYDQLTGKTVGVKNGTAAQRFLETIKDKYGFTIKTFD
                     TGDLMNNSLSAGAIDAMMDDKPVIEYAINQGQDLHIEMDGEAVGSFAFGVKKGSKYEH
                     LVTEFNQALAEMKKDGSLDKIIKKWTASSSSAVPTTTTLAGLKAIPVKAKYIIASDSS
                     FAPFVFQNSSNQYTGIDMELIKAIAKDQGFEIEITNPGFDAAISAVQAGQADGIIAGM
                     SVTDARKATFDFSESYYTANTILGVKESSNIASYEDLKGKTVGVKNGTASQTFLTENQ
                     SKYGYKIKTFADGSSMYDSLNTGAIDAVMDDEPVLKYSISQGQKLKTPISGTPIGETA
                     FAVKKGANPELIEMFNNGLANLKANGEFQKILDKYLASESSTASTSTVDETTLWGLLQ
                     NNYKQLLSGLGITLALALISFAIAIVIGIIFGMFSVSPYKSLRVISEIFVDVIRGIPL
                     MILAAFIFWGIPNFIESITGQQSPINDFVAGTIALSLNAAAYIAEIVRGGIQAVPVGQ
                     MEASRSLGISYGKTMRKIILPQATKLMLPNFVNQFVIALKDTTIVSAIGLVELFQTGK
                     IIIARNYQSFKMYAILAIFYLVIITLLTRLAKRLEKRIR"
     gene            59074..60027
                     /locus_tag="VQ540_000061"
     CDS             59074..60027
                     /locus_tag="VQ540_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000792120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET2543944.1"
                     /translation="MKNKRIFKDFQASKMNLNLYTSPLLAFVFVFIGEFVAYTLYGIS
                     LLALIGLARNFGEAGQNLASYLQTLHQSLTDKTSDFRLILGLLAFGFILNTVFRWTRK
                     VEKRPIRTLGFYRENCLSNLLKGFSLGLALFLLTLLSLVVLGQYRLESIHLNPYYLAF
                     VVFTIPFWILQGTAEEVVARAWLLPQLASRTNLKLAILISSLFFTLLHMGNSGLTPLS
                     LVNLFLFGVAMALYLLKTDTVWGVAGIHGAWNFAQGNLFGILVSGQPSGTSLMTFLPQ
                     GNQDWLSGGSFGIEGSIMTSLVLLLLIVYLANKLKKENERM"
     gene            60104..62092
                     /gene="uvrB"
                     /locus_tag="VQ540_000062"
     CDS             60104..62092
                     /gene="uvrB"
                     /locus_tag="VQ540_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit B"
                     /protein_id="HET2543945.1"
                     /translation="MINHITDNQFKLVSKYQPSGDQPQAIEQLVDNIEGGEKAQILMG
                     ATGTGKTYTMSQVISKVNKPTLVIAHNKTLAGQLYGEFKEFFPENAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSALLERNDVIVVASVSCIYGLGSPKEYA
                     DSVVSLRPGLEISRDKLLNDLVDIQFERNDIDFQRGRFRVRGDVVEIFPASRDEHAFR
                     VEFFGDEIDRIREVEALTGQVLGEVDHLAIFPATHFVTNDDHMEVAIAKIQAELEEQL
                     AVFEKEGKLLEAQRLKQRTEYDIEMLREMGYTNGVENYSRHMDGRSEGEPPYTLLDFF
                     PDDFLIMIDESHMTIGQIKGMYNGDRSRKEMLVNYGFRLPSALDNRPLRREEFESHVH
                     QIVYVSATPGDYENEQTETVIEQIIRPTGLLDPEVEVRPTMGQIDDLLGEINARVEKN
                     ERTFITTLTKKMAEDLTDYFKEMGIKVKYMHSDIKTLERTEIIRDLRLGVFDVLVGIN
                     LLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNSEGHVIMYADTVTQSMQ
                     RAIDETARRRKIQMAYNEEHGIVPQTIKKEIRDLIAVTKAVAKEEDKEVDINSLNKQE
                     RKELVKKLEKQMQEAVEVLDFELAAQIRDMMLEVKALD"
     gene            62102..62665
                     /locus_tag="VQ540_000063"
     CDS             62102..62665
                     /locus_tag="VQ540_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2543946.1"
                     /translation="MIYLRKLKREDLMSLWEMAYSQLNPVWKQYDAPYYDDYQYFSNF
                     KEFELQKSESILSNSNRLGIFVDDKLVGTVSRYWVCKQTRWMELGIGIYDKKFWNTGI
                     GKVAMLQWIDRTFQDYLELEHLGLTTWSGNLGMMKLAEKLRMKKEAHIPKVRYYQGKY
                     FDSIKYGILREDWEKTNDGYYQINGNS"
     gene            62631..63119
                     /locus_tag="VQ540_000064"
     CDS             62631..63119
                     /locus_tag="VQ540_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2543947.1"
                     /translation="MTVIIKSMETPEEIEGKPLVHWQTWREAYDGLLPAEFQETMTLE
                     RCRFFSQKYPENTLIAMDGMKVVGFISYGNFRDETIQAGEIIALYVLKDYYGKGIAQK
                     LIKAALIALNHFSEIFLWVLKDNKRAIAFYQKMGFTFDEQEKILELGKPIKEKRMVFY
                     SK"
     gene            63192..63659
                     /locus_tag="VQ540_000065"
     CDS             63192..63659
                     /locus_tag="VQ540_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HET2543948.1"
                     /translation="MSRAQLTILTNICLIEDLEAQRVVMQYRAPETNRWSGYAFPGGH
                     VENGESFAESVIREIYEETGLTIQNPQLVGIKNWPLDTGGRYIVVCYKATEFSGTLRS
                     SDEGEVSWVQKDQIPNLDLAYDMLPLMEMMEASDKSEFFYPRRTEDDWEKKIF"
     gene            complement(63656..64171)
                     /locus_tag="VQ540_000066"
     CDS             complement(63656..64171)
                     /locus_tag="VQ540_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HET2543949.1"
                     /translation="MTKDRKQALLQLLKEAPKALNGQSLAEHFHVTRQVIVQDIAILR
                     ADGAPILSTNRGYIYKQIDTNPYVHKLFKVKHEVEEIGQELLAIVDNGGHVQNTLIDH
                     PVYGEIETLLKLSCRRDVQHFLEQVEHSDFKPLSELTDGVHYHLVEAETQQDLHYIEE
                     ALDQLGYLVKD"
     gene            complement(64183..64710)
                     /locus_tag="VQ540_000067"
     CDS             complement(64183..64710)
                     /locus_tag="VQ540_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HET2543950.1"
                     /translation="MNTRKKTQFMTMTALLTAIAILIPIVMPFKIVIPPASYTLGSHI
                     AIFIAMFLSPLMAVFVILASSFGFLMAGYPMVIVFRAFSHISFGALGSLYLQKFPDTL
                     DKPKSSWVFNFVLAVVHALAEVLACVLFYATSGTNVENMFYVLFVLVGFGTIIHSMVD
                     YTLALAVYKVLRKRR"
     gene            complement(64988..65551)
                     /locus_tag="VQ540_000068"
     CDS             complement(64988..65551)
                     /locus_tag="VQ540_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HET2543951.1"
                     /translation="MKKRSNIAPIAIFFATMLVIHFLSSLIFNLFPFPIKPTIVHIPV
                     IIASIIYGPRVGVTLGFLMGLLSLTVNTITILPTSYLFSPFVPNGNIYSAIIAIVPRI
                     LIGLTPYLVYKLMKNKTGLILAGALGSLTNTIFVLGGIFFLFGNVYNGNIQLLLATVI
                     STNSIAELVISAILTLAIVPRLQTLKK"
     gene            complement(65535..66086)
                     /gene="coaC"
                     /locus_tag="VQ540_000069"
     CDS             complement(65535..66086)
                     /gene="coaC"
                     /locus_tag="VQ540_000069"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HET2543952.1"
                     /translation="MANILLAVTGSIASYKSADLVSSLKKQGHQVTVLMTQAATEFIQ
                     PLTLQVLSQNPVHLDVMKEPYPDQVNHIELGKKADLFIVVPATANTIAKLAHGFADNM
                     VTSTALALPSHIPKLIAPAMNTKMYDHPVTQNNLKTLETYGYQLIAPKESLLACGDHG
                     RGALADLTIILERIKETIDEKTL"
     gene            complement(66098..66787)
                     /gene="coaB"
                     /locus_tag="VQ540_000070"
     CDS             complement(66098..66787)
                     /gene="coaB"
                     /locus_tag="VQ540_000070"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000699493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HET2543953.1"
                     /translation="MKILVTSGGTSEAIDSVRSITNHSTGHLGKIITETLLSAGHEVC
                     LITTKRALKPEPHPNLSIREITNTKDLLIEMQERVQDYQVLIHSMAVSDYTPVYMTGL
                     EEVQASSNLKEFLSKQNHQAKISSTDEVQVLFLKKTPKIISLVKEWNPTIHLIGFKLL
                     VDVTEDHLVDIARKSLIKNQADLIIANDLTQISADQHRAIFVEKNQLQTVQTKEEIAE
                     LLLEKIQAYHS"
     gene            67017..68687
                     /locus_tag="VQ540_000071"
     CDS             67017..68687
                     /locus_tag="VQ540_000071"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HET2543954.1"
                     /translation="MKTDIEIAQSIELKPIVDVVEKLGISYDDLELYGKYKAKLSFDK
                     IRAVESNPVGKLILVTAINPTPAGEGKSTLTIGLADALNKIGKKTMIAIREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALIDNHLHQGNELEIDQRR
                     ILWKRVVDLNDRALRHVTVGLGGPLNGIPREDGFDITVASEIMAILCLATDIEDLKRR
                     LANIVIGYRYDRTPVSVGDLQVEGALALILKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSVLATTTALHLADYTVTEAGFGADLGAEKFLDIKTPNLPTSPDAVVIVATLRAL
                     KMNGGVAKDALTEENVEAVRAGFANLKRHVENIRKFGIPAVVAINEFVSDTEAEIAVL
                     KELCASIDVPVELASVWADGAEGGVALAETVVKTIAENPANYKRLYDNALSVQEKIEK
                     IVTEIYRGSKVNFEKKAQTQIAQIVQNGWDKLPICMAKTQYSFSDNPNALGAPENFEI
                     TIRELVPKLGAGFIVALTGDVMTMPGLPKRPAALNMDVESDGTVLGLF"
     gene            69015..70190
                     /gene="mutY"
                     /locus_tag="VQ540_000072"
     CDS             69015..70190
                     /gene="mutY"
                     /locus_tag="VQ540_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HET2543955.1"
                     /translation="MLDLKEYGIVMWPEEKVISFREKLLAWYDENKRDLPWRRSKNPY
                     HIWVSEIMLQQTRVDTVIPYYERFLDWFPTVESLATAPEESLLKAWEGLGYYSRVRNM
                     QAAAQQIMTDFGGQFPNTYEGISSLKGIGPYTAGAISSIAFNLPEPAVDGNVMRVLAR
                     LFEVNHDIGIPSNRKIFQAMMEILINPDRPGDFNQALMDLGSDIESPVNPRPEESPVK
                     DFSAAYQNGTMDRYPIKSPKKKPVPIYLKALVVKNSQGQFLLEKNESEKLLAGFWHFP
                     LIEVDNFSQEEQFDLFHQVAEESVNFGPSPEESFQQDYDLDVDWLDVCFDTVQHVFSH
                     RKWHVQIVAGQVSDFHDFSDREVRWLSPEEFKNYPLAKPQQKIWQAYAQANLDSSQD"
     gene            70245..70949
                     /locus_tag="VQ540_000073"
     CDS             70245..70949
                     /locus_tag="VQ540_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000722069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET2543956.1"
                     /translation="MKKILIVDDEKPISDIIKFNMTKEGYEVVTAFNGREALEQFEAE
                     QPDIIILDLMLPEIDGLEVAKTIRKTSSVPILMLSAKDSEFDKVIGLELGADDYVTKP
                     FSNRELQARVKALLRRSQPMPVDGQEADSKPQPIQIGDLEIVPDAYVAKKYGEELDLT
                     HREFELLYHLASHTGQVITREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPE
                     YILTRRGVGYYMRNNA"
     gene            70942..72291
                     /gene="vicK"
                     /locus_tag="VQ540_000074"
     CDS             70942..72291
                     /gene="vicK"
                     /locus_tag="VQ540_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     VicK"
                     /protein_id="HET2543957.1"
                     /translation="MLDLLKQTIFTRDFIFILILLGFILVVTLLLLENRRDNIQLKQI
                     NQKVKDLIAGDYSKVLDMQGGSEITNITNNLNDLSEVIRLTQENLEQESKRLNSILFY
                     MTDGVLATNRRGQIIMINDTAKKQLGLVKEDVLNRSILELLKIEENYELRDLITQSPE
                     LLLDSQDINGEYLNLRVRFALIRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSH
                     ELRTPLTSVKSYLEALDEGALCETVAPDFIKVSLDETNRMMRMVTDLLHLSRIDNATS
                     HLDVELINFTAFITFILNRFDKMKGQEKEKKYELVRDYPINSIWMEIDTDKMTQVVDN
                     ILNNAIKYSPDGGKITVRMKTTEDQMILSISDHGLGIPKQDLPRIFDRFYRVDRARSR
                     AQGGTGLGLSIAKEIIKQHKGFIWAKSEYGKGSTFTIVLPYDKDAVKEEVWEDEVED"
     gene            72293..73102
                     /locus_tag="VQ540_000075"
     CDS             72293..73102
                     /locus_tag="VQ540_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HET2543958.1"
                     /translation="MSEIGFKYSILASGSSGNSFYLETSKKKLLVDAGLSGKKITSLL
                     AEINRKPEDLDAILITHEHSDHIHGVGVLARKYGMDLYANEKTWQAMENSKYLGKVDS
                     SQKHIFEMGKTKTFGDIDIESFGVSHDAVAPQFYRFMKDDKSFVLLTDTGYVSDRMAG
                     IVENADGYLIEANHDVEILRSGSYAWRLKQRILSDLGHLSNEDGAEAMIRTLGNRTKK
                     IYLGHLSKENNIKELAHMTMVNQLAQADLGVGVDFKVYDTSPDTATPLTEI"
     gene            73193..73435
                     /locus_tag="VQ540_000076"
     CDS             73193..73435
                     /locus_tag="VQ540_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HET2543959.1"
                     /translation="MTTITLKVSEADKTFMKAMAKFEGVSLSELIRTKTLEALEDEYD
                     ARVADLAYQEYLEDLEKGVEPITWEEMMHDLGLKDE"
     gene            73437..73691
                     /locus_tag="VQ540_000077"
     CDS             73437..73691
                     /locus_tag="VQ540_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HET2543960.1"
                     /translation="MYKLVPTRRFIKQLKKLDRYTQKLITNYLQTNVLEDPRRHGKAL
                     VGNRVGQWRYRIGNYRVIVQIVDDELVVATLEVGHRRDIY"
     gene            73738..74511
                     /locus_tag="VQ540_000078"
     CDS             73738..74511
                     /locus_tag="VQ540_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ion transporter"
                     /protein_id="HET2543961.1"
                     /translation="MKKKWFFADYYDTTIILLALISVILVLLGFAEMIDLDNPPYSII
                     DLVIWGVFVIDYSWRFFTTKRKWRFILENIFDLLAILPLNAIFTVFRLGRIFRLAKLT
                     KLLKLTRLLRIIGLTGKLERKISRFLRTNGLIYILYVNIFIVLVGSSILSVVEEKSFS
                     DSLWWALVTVTTVGYGDIVPASIFGKWLAVLLMLVGIGTIGMLTSALTNFFVKDNPDE
                     QIKLDKLKDELSSQRILLEKQSKKIEELHKMIQDLIEKT"
     gene            complement(74771..75757)
                     /locus_tag="VQ540_000079"
     CDS             complement(74771..75757)
                     /locus_tag="VQ540_000079"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019768616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HET2543962.1"
                     /translation="MTSTKQHKKVILVGDGAVGSSYAFALVNQGIAQELGIIEIPQLH
                     EKAVGDALDLSHALAFTSPKKIYAAQYSDCADADLVVITAGAPQKPGETRLDLVGKNL
                     AINKSIVTQVVESGFKGIFLVAANPVDVLTYSTWKFSGFPKERVIGSGTSLDSARFRQ
                     ALAEKLDVDARSVHAYIMGEHGDSEFAVWSHANIAGVNLEEFLKDTQNVQEAELIELF
                     EGVRDAAYTIINKKGATYYGIAVALARITKAILDDENAVLPLSVFQEGLYGVENVFIG
                     QPAVVGAHGIVRPVNIPLNDAETQKMQASAKELQAIIDEAWKNPEFQEASKN"
     gene            75951..78419
                     /gene="gyrA"
                     /locus_tag="VQ540_000080"
     CDS             75951..78419
                     /gene="gyrA"
                     /locus_tag="VQ540_000080"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003244540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HET2543963.1"
                     /translation="MQDKNLVNVNLTKEMKASFIDYAMSVIVARALPDVRDGLKPVHR
                     RILYGMNELGVTPDKPHKKSARITGDVMGKYHPHGDSSIYEAMVRMAQWWSYRYMLVD
                     GHGNFGSMDGDSAAAQRYTEARMSKIALEMLRDINKNTVDFVDNYDANEREPLVLPAR
                     FPNLLVNGATGIAVGMATNIPPHNLGETIDAVKLVMDNPEVTTKDLMEVLPGPDFPTG
                     ALVMGKSGIHKAYETGKGSIALRSRTEIETTKTGRERIVVTEFPYMVNKTKVHEHIVR
                     LVQEKRIEGITAVRDESNREGVRFVIEVKRDASANVILNNLFKMTQMQTNFGFNMLAI
                     QNGIPKILSLRQILDAYIEHQKEVVVRRTRFDKEKAEARAHILEGLLIALDHIDEVIR
                     IIRASETDAEAQAELMSKFKLSERQSQAILDMRLRRLTGLERDKIQSEYDDLLALIAD
                     LADILAKPERVSQIIKDELDEVKRKFSDKRRTELMIGQVLSLEDEDLIEESDVLITLS
                     NRGYIKRLDQDEFTAQKRGGRGVQGTGVKDDDFVRELVSTSTHDHLLFFTNKGRVYRL
                     KGYEIPEYGRTAKGLPVVNLLKLDEDESIQTVINVESDRSDDAYLFFTTRHGIVKRTS
                     VKEFANIRQNGLKALNLKDEDELINVLLAEGDMDIIIGTKFGYAVRFNQSAVRGMSRI
                     ATGVKGVNLREGDTVVGASLITDQDEVLIITEKGYGKRTVATEYPTKGRGGKGMQTAK
                     ITEKNGLLAGLMTVQGDEDLMIITDTGVMIRTNLANISQTGRATMGVKVMRLDQDAQI
                     VTFTTVAVAEKEEVGTENETEGEE"
     gene            78419..79162
                     /gene="srtA"
                     /locus_tag="VQ540_000081"
     CDS             78419..79162
                     /gene="srtA"
                     /locus_tag="VQ540_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase SrtA"
                     /protein_id="HET2543964.1"
                     /translation="MSQKNNKKKNKRKNLLTNILAGFLILLSLALIFNTQIRNIFIVW
                     NTNKYQVSQVSKEKLEENQDTEGNFDFDSVKAISSEAVLTSQWDAQKLPVIGGIAIPE
                     LEMNLPIFKGLDNVNLFYGAGTMKREQVMGEGNYSLASHHIFGVDNANKMLFSPLDNA
                     KNGMKIYLTDKNKVYTYEIREVKRVTPDRVDEVDDRDGVNEITLVTCEDLAATERIIV
                     KGDLKETKDYSQTSDEILTAFNQPYKQFY"
     gene            79406..80203
                     /locus_tag="VQ540_000082"
     CDS             79406..80203
                     /locus_tag="VQ540_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HET2543965.1"
                     /translation="MVSSEFISKIEFACNKKESLYSQSKFKYAIRSMFAGAFLTFSTA
                     AGAVGADLINKIAPGSGRFLFPFVFAWGLAYIVFLNAELVTSNMMFLTAGSFLKKISW
                     RKTAEILLYCTLFNLIGALIAGWGFAHSAAYANLTHDSFISGVVEMKLGRSNELVLLE
                     AILANIFVNIAILSFILVKDGGAKLWLVLSAIYMFVFLTNEHIAANFASFAIVKFSVA
                     ADSIANFGVGNMLRHWGVTFIGNFIGGGLLMGLPYAFLNKNEDTYVD"
     gene            80351..80473
                     /locus_tag="VQ540_000083"
     CDS             80351..80473
                     /locus_tag="VQ540_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent transferase"
                     /protein_id="HET2543966.1"
                     /translation="MTCDFKFETLQLHAGQVVAPATKSRAVPIYQTTSFIFDDT"
     gene            80495..81535
                     /locus_tag="VQ540_000084"
     CDS             80495..81535
                     /locus_tag="VQ540_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001231001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetylhomoserine
                     aminocarboxypropyltransferase/cysteine synthase"
                     /protein_id="HET2543967.1"
                     /translation="MRKPGNIYTRITNPTTAALEGGVEALATASGMTAVTYTILALAH
                     AGDHVVAASTIYGGTFNLLKEPLPRYGITTTFVDVDNLEEVEAAIKDNTKLVLIETLG
                     NSLINIPDLEKLAEIAHKHQIPLVSDNTFAIPYLINVFSHGVDIAIHSATKFIGGHGT
                     TIGGIIVDSGRFDWTASGKFPQFVDEGPSCHNLSYTCDVGAAAFIIAVRVQLLRDTGA
                     ALSPFNAFLLLQRLETSSLRVERHVQNAETIVDFLVNHPKVEKVNYPKLADSPYHALA
                     EKYLPKDVGSIFTFHVKGGEEEARKVIDNLEIFSDLANAADAKSLVVHPATTTHGQLS
                     EKDLEAAGVTPN"
     gene            81706..82980
                     /locus_tag="VQ540_000085"
     CDS             81706..82980
                     /locus_tag="VQ540_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2130 domain-containing protein"
                     /protein_id="HET2543968.1"
                     /translation="MNEIKCPNCGEVFTVNESQYAELLSQVRTAEFDKELHDRMKQEL
                     ALAEQKAMNEQQTKLAQKDQEIAQLQSQIQNFDTEKELAKKEVEQTSHEALLAKDKEV
                     QLLENQLATLRLEHENQLQKTLSDLEKERDQVKNQLLLQEKENELSLASVKQNYEAQL
                     KAASEQVEFYKDFKAQQSTKAIGESLEQYAESEFNKVRSFAFPNAYFEKDNKVSSRGS
                     KGDFIFRECDENGVEIISIMFEMKNEADGTEKKHKNADFYKELDKDRREKNCEYAVLV
                     TMLEADNDYFNTGIVDVSHEYEKMYVVRPQFFIQLIGLLRNAALNSLKYKQELALVRE
                     QNIDITHFEEDLDAFKLAFAKNYNSASTNFGKAIDEIDKAIKRMEEVKKFLTTSENQL
                     RLANNKLEDVSVKKLTRKNPTMKAKFEALKGE"
     gene            82990..83868
                     /gene="truB"
                     /locus_tag="VQ540_000086"
     CDS             82990..83868
                     /gene="truB"
                     /locus_tag="VQ540_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HET2543969.1"
                     /translation="MNGIINLKKEAGMTSHDAVFKLRKILGTKKIGHGGTLDPDVVGV
                     LPIAVGKATRMVEFMQDEGKIYEGEIILGYSTTTEDASGEVVAETPVLSPLDEKLVDE
                     AIASLTGPITQIPPMYSAVKVNGRKLYEYARAGQEVERPERQVTIYQFERTSPISYDG
                     QLARFTFRVKCSKGTYIRTLSVDLGEKLGYAAHMSHLTRTSAAGLQLEDALTLEEIAE
                     KVEAGQLDFLHPLEIGTGDLVKVFLTPEEATEVRFGRFIELDQTDKELAAFEDDKLLA
                     ILEKRGNLYKPRKVFS"
     gene            84136..84411
                     /locus_tag="VQ540_000087"
     CDS             84136..84411
                     /locus_tag="VQ540_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HET2543970.1"
                     /translation="MEQLLQQKEINENSELSHLFRLAIQNLDRNEKYQSVMANLSQGL
                     SLYLMTHHYQAPKSVIDFGLWIAKAPSQERGRLAFLQMLAQTLQGFR"
     gene            84519..85157
                     /gene="udk"
                     /locus_tag="VQ540_000088"
     CDS             84519..85157
                     /gene="udk"
                     /locus_tag="VQ540_000088"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HET2543971.1"
                     /translation="MQNRPIIIGVTGGSGGGKTSVSRAILSHFPDEKISMIEHDSYYK
                     DQSHLTFEERVKTNYDHPFAFDTDLMIEQIKELLAGRPVDIPTYDYTEHTRSSKTYRQ
                     EPQDVFIVEGILVLEDKRLRDLMDIKIFVDTDDDVRIIRRIKRDMEERGRSLDSVINQ
                     YLGVVKPMYHQFIESTKRYADIVIPEGVSNTVAIDLLTTKIAKILEEARNSK"
     gene            85285..86625
                     /locus_tag="VQ540_000089"
     CDS             85285..86625
                     /locus_tag="VQ540_000089"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HET2543972.1"
                     /translation="MEKYLSVTTLTKYLKMKFDKDPYLERVYLTGQVSNFRKRPTHQY
                     FSLKDDHAVIQATIWSGIYQKLGFDLEEGMKINVIGRVQVYEPSGSYSIIIEKAEPDG
                     VGALAIQFEQLKKKLTEEGLFQERFKQALPQFSKRIGVVTSRSGAVIRDIITTVSRRF
                     PGVDILLYPTKVQGEGAAEEIARNIARANQRDDLDLLIIGRGGGSIEDLWAFNEEIVV
                     RAIFESRLPVISSVGHETDVTLADFVADRRAATPTAAAELATPVTKLDVLAHLQNQEK
                     RMATAVRNVLSKKQEALKKCSQSVIFRQPERLYDGYLQRLDQLQLRLKQSLRTRISDN
                     KQLVQARTHQLVQLSPVTKIQRYQDRLGQLDKLLGSQMALVYDAKVAEAKRLSEALLM
                     LDTSRIVARGYAIVKKEESVVDSVESLKKKDQVTLLMRDGQVELEVKDVKTKEI"
     gene            86603..86815
                     /locus_tag="VQ540_000090"
     CDS             86603..86815
                     /locus_tag="VQ540_000090"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HET2543973.1"
                     /translation="MSKQKKFEENLAELETIVQSLENGEIALEDAITAFQKGMVLSKE
                     LQATLDKAEKTLVKVMQEDGTESDFE"
     gene            86812..87687
                     /locus_tag="VQ540_000091"
     CDS             86812..87687
                     /locus_tag="VQ540_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HET2543974.1"
                     /translation="MKKQEKLALVESALEDFYGDQQFASSLRESVLYSIHAGGKRIRP
                     FLLLEVLESLQVTIKPAHAQVATALEMIHTGSLIHDDLPAMDDDDYRRGRLTNHKKFG
                     EAMAILAGDALFLDPYALIAQADLPSQIKVDLIANLSLASGSLGMVAGQVLDMEGEHQ
                     HLSLEELQTIHANKTGKLLAYPFQAAAIIAELSPEMQVKLKTVGELIGLAFQVRDDVL
                     DVTASFEEIGKTPQKDLQAEKSTYPALLGLEESIAFCNQTLDQANEKLEEIAQQLPFE
                     TESIVSVVESLRING"
     gene            87680..88495
                     /locus_tag="VQ540_000092"
     CDS             87680..88495
                     /locus_tag="VQ540_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HET2543975.1"
                     /translation="MAKERVDVLAYKQGLFETREQAKRGVMAGLVVAVLNGERFDKPG
                     EKIPDDTELKLKGEKLKYVSRGGLKLEKALQVFDLSVDGATTIDIGASTGGFTDVMLQ
                     NSAKLVFAVDVGTNQLAWKLRQDPRVVSMEQFNFRYAEKTDFEQEPSFASIDVSFISL
                     SLILPALHSVLADQGQVVALVKPQFEAGREQIGKNGIIRDAKIHQNVLESVTAMAVEA
                     GFSVLGLDFSPIQGGHGNIEFLAYLKKEKSASNQILAEIKEAVERAHSQFKNE"
     gene            88488..88919
                     /locus_tag="VQ540_000093"
     CDS             88488..88919
                     /locus_tag="VQ540_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001034407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HET2543976.1"
                     /translation="MNKKERLEKIRRLVTDYQIGTQEEIVEHLKEAGITATQATVSRD
                     IKELGIVKIPLRDNTYVYELPKSIVKSLQLAEDNIESAELMDKMINLQVIPGNTAFVK
                     AQLIETFADKIFSCLTDDSSILVIARSGSLAEEIFEQVKNW"
     gene            88926..90593
                     /gene="recN"
                     /locus_tag="VQ540_000094"
     CDS             88926..90593
                     /gene="recN"
                     /locus_tag="VQ540_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HET2543977.1"
                     /translation="MLLEISIKNFAIIEAISLNFEKGMTVLTGETGAGKSIIIDAMNM
                     MLGARATTDVIRHGAPKAEIEGLFSVENSRLLQEIFDEQGLELGDEIIIRREILQNGR
                     SISRVNGQMVNLSVLRTIGQHLVDIHGQHDHEELMRPQLHIQMLDEFGDAAFWDLKET
                     YQTSFDAYRKMRKQVLEVKKNQQEHKARIEMLEFQMAEIEAANLQAGEDLDLNQERDK
                     LLNHKNIADTLTNAYSMLDNEDFSSLANVRSAMNDMESVEEYDPEYREISSSLSETYY
                     VLEDISKRLEAIIEDLDFDGNRLMQVENRLDLLHTITRKYGGTVDDVLLYFAKITEEY
                     NLLTGNNLSSEDMEAELKKLEVNLVNLAGQLASARHNLAQQLEAEIKQELQDLYMEKA
                     QFQVRFSKGKFSREGNKMVEFYISTNPGEDFKPLVKVASGGELSRLMLAIKSAFSRKE
                     GKTSIVFDEVDTGVSGRVAQAIAQKIHKIGQHGQVLAISHLPQVIAIADYQFFIEKIS
                     NDHSTVSTVRLLTVEERVEEVAKMLAGDDVTEAALTQARELLRNREK"
     gene            90595..91323
                     /locus_tag="VQ540_000095"
     CDS             90595..91323
                     /locus_tag="VQ540_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000133310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein phosphatase"
                     /protein_id="HET2543978.1"
                     /translation="MTDYYVIGDVHGKAGMLEDLLKTWDGQPQLLFLGDLIDRGEDSH
                     RVLEMVKDLVDNQGAICLSGNHEYMFLTWLDDPEESYDHYSRNGGDTTINSILGRPLD
                     APVDGVEDAKRVAAEAADLVEFIRQMPFVVETDKYIFVHAGIDLTLDDWHETTDYKKV
                     WLRKPFHGAENHTGKTIVFGHTPVYGLLQQERGTSELWTTEDGKIGMDGGAVYGGVLH
                     GIVFTDQGMTEHHFIENDGFVAED"
     gene            91402..93225
                     /gene="lepA"
                     /locus_tag="VQ540_000096"
     CDS             91402..93225
                     /gene="lepA"
                     /locus_tag="VQ540_000096"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001047203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HET2543979.1"
                     /translation="MNLEELKKRQEKIRNFSIIAHIDHGKSTLADRILEKTETVSSRE
                     MQAQLLDSMELERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAILVVDAAQGIEAQTLANVYLALDNDLEIMPIINKIDLPAADPERVRTEIEDVI
                     GLDASEAVLASAKAGIGIEEILEQIVEKVPAPTGDVTAPLKALIFDSVYDAYRGVILQ
                     VRVMDGVVKPGDKIQLMSNSKTFDVAEVGIFTPKAVGRDFLATGDVGYIAASIKTVQD
                     TRVGDTVTLATNPAAEPLHGYKQMNPMVFAGLYPIESNKYNDLREALEKLQLNDASLQ
                     FEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVIYKVNLTDGESMD
                     VSNPSEFPDPTKIATIEEPYVKAQIMVPQEFVGAVMELAQRKRGDFVTMDYIDDNRVN
                     VIYQIPLAEIVFDFFDKLKSSTRGYASFDYELSEYRPSKLVKMDILLNGDKVDALSFI
                     VHKDFAYERGKLIVDKLKKIIPRQQFEVPIQAAIGHKIVARTDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKAGKKRMKSIGSVEVPQEAFLSVLSMDEE"
     gene            complement(93427..93507)
                     /locus_tag="VQ540_000097"
                     /pseudo
     CDS             complement(93427..93507)
                     /locus_tag="VQ540_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            93682..93991
                     /locus_tag="VQ540_000098"
                     /pseudo
     CDS             93682..93991
                     /locus_tag="VQ540_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="internal stop; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
BASE COUNT        28566 a        16795 c        20847 g        27783 t
ORIGIN      
        1 ccttaaagat tccgactaat attggctttg catttattcc tccatacaca ccagagatga
       61 acccattgaa caagtgtgga aagagattcg taaacgtgga tttaagaata aagcctttta
      121 aactttggaa gatgtcatga atcaactcca agatgttata caaggactgg agaaggaggt
      181 gataaagtcc atcgttaatc ggagatggac tagaatgctt tttgaaagca gatgagtata
      241 agtcctcgtt ttgaagcctt ggaacaggcc attgcctcca aagatttgga aaaagtccga
      301 gaagctttta agaaaatgaa ttccacttgg accatcaatg aaagtgtggt tcgtgacaat
      361 agtacagctc attatggacg tgttgaaaca gctatttcct tcctgcctag tagcatggaa
      421 accgaaccta cagatgagtc tggaacatga aaacagcagt tgatttcaag aaacaaaaaa
      481 gaacagtcga aactgttctt ttatcattat ttgagaccgt attttttgtt gaaacgatcc
      541 acgcgtccat ctgcttgagt gaacttttga cgtccagtgt agaatgggtg tgagtctgat
      601 gaaatttcca cacggatcaa tgggtaagtt tcgccttcga actcaactgt ttcgttagag
      661 cgttttgttg aaccgctaag gaattggtaa ccagtagttg tgtccatgaa gacaactggg
      721 cgatattctg gatggatatc ttttttcatt ttgcaatatt tcctttctgc catggtctct
      781 ttgcgagcca tagattgtta ccatactagt ctatcagatt ctgaaaagtt tggcaagtat
      841 tttatcagtt tttaagcaag ttttttaact tttggtagat gatttcattt tcttctaggc
      901 tataggaatt agcaccactt gctagagggt ggcctccacc atcatgctcc ttggcgattt
      961 cattgatagg atggatttta ctgcgtaagc gaacgcggta gtggccatca gcctgttcca
     1021 caaaaattcc ccagagacta acactatcaa tacgcccagg tgcacctaca atggccgcag
     1081 tttcagcatc ggttacattg tattgtttca agattttctg actcaggata acgcgagcag
     1141 caccattttc atccacttcc agatggtcgt agatgtagcc ttgcagttta gcaattttgt
     1201 agctcatagt gtccattttg cgagtgagag ccgcaaagtc aaagttatgt tctctcaaat
     1261 aagcagccag gcgaagagtc cgtgcagtgg tagaagggta gaggaagcga cctgtatcac
     1321 cgacaattcc tgcaaagagc aactcagcat cgcgatctgc caaggctagt tgggttgttt
     1381 gggcaaatag ggtaatcatc tcgctagcgc tacttgaact agtatcgacc caagacaggt
     1441 caccgtatac atcatcattt ggatggtggt caatcttaat gagaaaatca ccttgactat
     1501 agcgcttatc atcgatacga gcagtattag ctgtatcaca gacgatgaca agtgcgcctt
     1561 ggtaggctct atcttcaaca agatccatct cagccatcca agtaagagtt ggttcatcaa
     1621 aaccgacggc tttgatggtt ttttctggga aatgatgttc cagcaaggct ttcaatccca
     1681 cctgacttcc caaggcatca gggtctggtt tcatatgacg atgaatgata atggtgttgt
     1741 attctttaat tttttctaaa atttgttggc aaatctccat aaataacctc aattctttct
     1801 catttcattg tagcacaaga atttttattt ttaaaatgaa aaagatgtga tataatggag
     1861 aaagataaat tgaggaggac gatatggcat tagcaaaaat tgtatttgcc agtatgaccg
     1921 gtaataccga agaaattgca gatattgtag cagacaaatt acgtgacttg ggcttggatg
     1981 ttgatgttga tgaatgtaca actgttgacg cttcagactt cttggaagca gacatcgcta
     2041 tcgttgcgac ctatacttat ggtgatggtg aattgccaga tgagatgatg gacttctacg
     2101 aagacctagc agatctcaac ttgaatggca aaatctacgg agtggtcggc tcaggagata
     2161 ccttctacga tgaattctgt aaggctgttg atgactttga ccgtgtcttt gtgtcaacag
     2221 gagcagaaaa aggttcagag tgtgttaaag ttgatctttc tgccgaggaa gaagatattg
     2281 aacgcttgga acaattcgca gaagaattgg ctgctaaagt aggataagca taaaagtgcg
     2341 ctgatgtaat caatcagtgc atttttctta tcgagagttg ggattttact agcctaattg
     2401 atggcttttt gatacaataa ttcaaataaa ggaggagact gtatggattt agatattatt
     2461 cgtcaagaaa tcgatcaaat cgacgaccaa attgtcaaac tgttagaaga acgaatgcat
     2521 ttagttgagg gggtggttgc ttataagaaa gcttcaggta aaccgatttt agatactaag
     2581 agagaagaag ttatttttga aaaggttagg agtcgtgtag aggacaagcg ctatcaggag
     2641 actattgtcg cgactttttc gtacatactc aaacgttcgc gtgattatca ggatcaaaat
     2701 atcaaatgaa aaaagaacaa ttttatccgc taggaatttt tctagctgct atgttgggcg
     2761 gacttgtccg atatctagtt tccacctggt taccagccag tccagacttt ccttggggca
     2821 ctctctttgt caactatctg ggaattttct gcttgatttt tcttgtcaag ggctatctgg
     2881 tctataaggg gactagtaag ggcttgattt tagcactggg gacgggtttt tgcggaggtt
     2941 taacaacttt ttccagccta atgcttgata ctgtgaagct gcttgataca gggcgttatt
     3001 ttagtttagt cctgtatttg cttttgagta tcggtggagg cctgctttta gcttactatt
     3061 tggggaggaa gaaatggtaa tcgtctatct tgcaatcgcc tgtggcttgg gagcactcgt
     3121 acggtatttc ttttctcgct ataatcaagc ttctaaattg ccactcggaa cgctcatagc
     3181 taatctttta ggttgttttt taattggagt attctacaat catgtagagt ctaaggaagt
     3241 atatgctatt ctagcaacag gattttgtgg cggtttaaca actttttcga ccttgaatga
     3301 cgaacttcaa agactgctaa gtgataagaa ggtcttttat tcttacctga ctttgactta
     3361 cataggtggt ttggttgcga tttttttagg aattttgcta taaatttctt tacttttttt
     3421 tagaaatttg gtaaactata tcttgtgtgt aatggacgca caaaaataca gtttatccgc
     3481 tgaggaagat tcctcaagat tgacaaagat aggagaataa aatgaatcca ttaatccaaa
     3541 gcttgactga aggtcaactt cgtacagata tcccatcatt ccgtcctggt gacactgttc
     3601 gtgtacatgc gaaagttgtc gaaggtaacc gtgaacgtat ccagattttt gaaggtgttg
     3661 ttattgcacg taaaggtgct ggcatctctg aaaactacac agttcgtaaa atctctaacg
     3721 gtgtaggtgt tgagcgtatc ttcccaatcc acactccacg tgttgaaaaa atcgaagttg
     3781 tacgttacgg taaagtacgt cgtgcgaaat tgtactactt gcgtgctctt caaggtaagg
     3841 cagctcgtat caaagaaatc cgtcgttaat tcgactaaaa aactctgctt tttcagcaga
     3901 gtttttatct agctccctta gttcaatgga tataacaact ccctcctaag gagtagttgc
     3961 aggttcgatt cctgcagggg gcatgtaatt agatatcaaa gaagtttgtc aaagagtctt
     4021 tgatattaaa agaacgcata atatagggga ttgtctccat aatattatgc gttttattat
     4081 tgaaaaattt gggcaatcat cagataaaat tgagactata tcgagtatat aaatgtttgt
     4141 atagtcaatt tattcaaaat cgtcaagttc taaattattt aaaggactat aacattcata
     4201 tttctttaag taattgttta tttcttcagc agtggaacga ggtaaattaa ctcttaaata
     4261 gtcaatatct tccttagata aaaaatgatt tgcattcaaa attgagaagc gaaataatgc
     4321 ttcatcaaaa gcaaaatcat aatcgtcatc agataatgat tccattaatg tttgaatatg
     4381 ttttagtgag tagtcaggta tcgaatcggg ataatatact ggataatcag tggctgaaaa
     4441 attgttttct aatcctgaaa tagtaattat caaagattct atgtaatata ttaaagcatg
     4501 tttaatatta ccttcttgtt ccaaatgtct tccctgagcc tttcgtgtgt tagataagca
     4561 tccaaaatct cctgatacag tattcctatg agcttgttta tttaagagac tccattttat
     4621 atcaccaaaa gttgctttaa aagagatatt gtttttttct ttacaataat cttccatact
     4681 tatgtcttta tcatagtatg ctttgatata gtcactatgt tcgataataa gattttgtgc
     4741 ttcttttgtt agtttaaatt cgaacggaat atctaaattg tcaatgttaa cattattaat
     4801 tattcttgta attaattctg ctttttttcc agaagtagct aaattatgtt tagataatat
     4861 agtttttaat tctactactg taagatatga taaagtctta tttttagtga agtatcctaa
     4921 tttgtataat tgattgtgtg tagattcagg gtcaatttga agagagtatt taaaatatct
     4981 tgggaaatta taatttctcc ctgttttttg agtccaatct atgagtatga gttgcccagg
     5041 agtaaggcca cattctaatt cgtttaggta aaaattgtta caatcagaat ttgtgtctct
     5101 attatgatta ttttgtttta aattaaatag tttgctaaaa aaattcattg gattttattg
     5161 ctaatcaatt cttattgaaa aatgatactt ttacagtacc catgttcgga tggcatgggc
     5221 aacgccggat tcgtcatttg ttttggtgat gtatttggcg atttttttga tttctggatt
     5281 tccattttcc atgacaacgg ggtttccaac gacttccagc atgggacggt cattttcttc
     5341 atcaccgatt gccatggttt catctttggt caatccgagt ttttcagcca agtgagtaat
     5401 ggctgaaccc ttgtctacat tctttttaag gagttcgagg tagaaaggag cagatttgtt
     5461 gatggagtag cgctcgtaaa attctgctgg aattttttca atcgcagcat cgagaatttc
     5521 tggttcatcg ataaacatac atttaacaat ttctttgcca gccatttctt caggggtacg
     5581 gtagaagata ggcatgctga cgagggttga ttcgtgtaca gtgtattttc cgatattgcg
     5641 atttgcagta tagataccgt ccttggtaat ggcatgcatg tggacaccga gcttgcgact
     5701 gaggaattcc atatccagat aatcctcata ggtcaaggat tcgctgataa tctcatggcc
     5761 agtagcagtt tcttggacaa gggcaccatt gaaggtcacc acatagtcac cttggtctct
     5821 caactgcaag tcgtccagaa gtttggcaac acctgcgatg gggcggccag ttgcaatcac
     5881 gactttgaca ccagcttctt tggcatcttg gatggcagaa aagacttcag gagtgatttc
     5941 cttttggctg ttgactaggg ttccgtcaat atcgacggca attagtttaa tactcataaa
     6001 attcctcttc tagtttttat ttggggtaaa atgatcgttc tcaatcaagt gtaaaaattg
     6061 ctgggtaatg cttgcgaaga tgctgttttg gtctaacatt tctttaggga aatagaaacg
     6121 attatctccg tggcgactgc cagcaaggga ttggacgata ggagacaggc tagagagttc
     6181 ggccagttct ccattttttt gtaaaatctc aatctgtgtc cgtggatttt gagattcggg
     6241 acgatagata tcataaggga ggtcaaagtt cttatgaatg gcagtatagt agtcgggatc
     6301 aaagccgatg tcctcaacca attttctcat gctagtaagt tgatcttggt cctcttgtga
     6361 aaaggtaatg gatttaaaga ccttgcggtt gacaaagcgt tgagataaat ctgcaagaat
     6421 tttgtcagga ctagtcatcc aaagctggaa gtaggtattc atcacgccat catccagagc
     6481 cagatagtca gtcaaggtca catttttttc gaagaaaggc aggagatgtg gggaagttcg
     6541 tgcaaagaaa ttcttgtcct cagggtagag ttccttggcg cgcttgagaa gattctgtag
     6601 gagaacttcc atggcgcgtg ttgctgggtg gaaataaacc tgcatgtaca tctggtagcg
     6661 actgaggacg tagtcttcga tggcgtgcat gccattgcgc tgaaaggcga taccattttc
     6721 gacaggacga atgactcgga ggatgcgagt caggtcaaat tccccatagg atgctcctgt
     6781 aaaataggag tcgcgcaaga gatagtccat gcgatctgcg tcaatctgac tagaaatgag
     6841 ctgcacgacc tgcttattag gataggtatg gtcaatgaca ctggccacct tttctgggaa
     6901 atcaggtgcc acttgtagca ggacttggtg aatctctgtc tcaggatttt gaataatctc
     6961 ctgagtaatg gcttcatggt ctgtatcaaa gagattttca aaagtatggg agtaggcacc
     7021 atgcccaagg tcgtgtagga gagcagcggt cacggtcaag agagactcgg caggattcca
     7081 ttcctcagga tatttttctt cgaaaatctc tgtgatgcgt cgtgcaattt catagactcc
     7141 tagacagtga gagaagcgac tgtgttctcc accgtggaag gtataactgg aagttcccag
     7201 ttgtttgatc cggcgcaaac gctgaaattc ttttgtatta atcaagtcat agatgatttg
     7261 attattgaca tggatgtagt tgtgaactgg gtcacggaat actttttcgt tcatatgacc
     7321 attatagcaa aatcctgctc tttttggtaa aatagtagga caagagacaa gaaagagggc
     7381 ctgatgtgaa gattcggatg cgaaatacaa ttcagtttga tgagcagttg gaagtgattg
     7441 accagcttta tgatgtggaa gtgcatgaaa aaggagatta tagctacctg cttttctata
     7501 atgaggaaaa ggaaaaagta gtgattaaat ttcatggtca agaacttatg atgagccgat
     7561 tttctaatcc caagaccatt atgcgctttc taaaggatag cgatagttta gcctatattc
     7621 ctacacctat gggcatgcag gagtttatca tccaaacgag ccattatcaa gttgataggc
     7681 aaaagattga actagattat caactacaaa atcaagaggg acatcctttt gccagctatc
     7741 aattggaaat tacttggggc taggctcatg tctttttcaa atttagctat ctatcttctt
     7801 ggatcggctt cctagtgtgg tagattaggc taatttttgg tataataaaa gttatggaaa
     7861 tcgaaaaaac caatcgtatg aatgcgctct ttgaatttta tgcggcgctt ttgacagata
     7921 agcaaatgaa ttatatcgag ctctactacg ctgatgatta cagccttgct gaaattgccg
     7981 aggagtttgg tgtcagtcgt caggctgtct atgacaatat caagcgaaca gaaaagattc
     8041 tggaagatta tgagatgaaa ttgcacatgt actcggacta tattgtccgc agtcagattt
     8101 ttgatcagat tttggagcgc tatcccaagg atgactttct gcaggagcag atagaaattt
     8161 taacaagcat tgataataga gaataagagg aagaaaaatg gcatttgaaa gtttaacaga
     8221 acgtttgcag aacgtcttta aaaatctacg taaaaaagga aaaatctctg aatctgatgt
     8281 ccaagaggca accaaagaaa ttcgcttggc cttgctcgag gccgacgttg ccttgcctgt
     8341 tgtaaaggac tttatcaaga aagttcgtga gcgtgcagtc gggcatgagg tcattgatac
     8401 acttaatcct gcgcaacaga ttattaaaat cgttgatgag gaactgacag ccgttttagg
     8461 ttctgatacg gcagaaatta tcaagtcacc taagattcca accatcatca tgatggttgg
     8521 tttacaaggg gctggtaaaa caacctttgc tggtaaattg gccaacaaac tcaagaaaga
     8581 agaaaatgct cgtcctttga tgattgcggc ggatatttat cgtccagctg ccattgacca
     8641 gcttaagacc ttgggacaac agattgatgt gcctgtcttt gcacttggaa cagaagtacc
     8701 agctgttgag attgtacgtc aaggtttgga gcaagcccaa actaatcata acgactatgt
     8761 cttgattgat actgcgggtc gtttgcagat tgatgagctc ctcatgaatg agcttcgtga
     8821 tgtgaaagca ttggctcaac caaatgaaat cttgcttgtc gttgatgcta tgattggtca
     8881 ggaagcagcc aatgttgcgc gtgagtttaa tgctcagttg gaagtgactg gggtcatcct
     8941 taccaagatt gatggcgata ctcgtggtgg tgctgctctg tctgttcgtc acattactgg
     9001 aaaaccaatc aagttcactg gtacaggtga aaagattacg gacattgaaa ccttccaccc
     9061 agaccgcatg tctagccgta tccttggtat gggggatatg ctcactttga ttgagaaagc
     9121 ttctcaggaa tacgatgaac aaaaagccct tgaaatggct gagaagatgc gcgaaaacac
     9181 ctttgatttt aatgatttca tcgatcaatt agatcaggtg caaaatatgg ggccgatgga
     9241 agacttgctc aagatgattc caggtatggc caacaatcca gcccttcaaa acatgaaggt
     9301 ggatgaacgc cagattgctc gtaaacgtgc cattgtgtct tcgatgacac ctgaagagcg
     9361 tgaaaaccca gatttgttaa atccaagccg tcgccgtcgt attgctgctg gttctggaaa
     9421 tacattcgtc gaagtcaata aattcatcaa ggactttaac caggctaaac agctcatgca
     9481 gggtgttatg tctggggata tgaataaaat gatgaagcaa atggggatta atccaaataa
     9541 ccttcctaaa aatatgccaa atatgggagg aatggatatg tctgcccttg aaggaatgat
     9601 gggacaaggc ggtatgcctg acttatcagc tctcggagga gcaggaatgc cagatatgag
     9661 ccagatgttt ggtggcggtt tgaaaggtaa aattggtgaa tttgccatga aacagtccat
     9721 gaaacgtatg gctaacaaaa tgaagaaagc gaagaagaaa cgcaagtaag acaagagatt
     9781 gatgcaaatc tcatttgatg agaaaataaa gtaaaaattt ctatgataaa acgtacagta
     9841 tcaaggtttt agaatatctg atattatacg ttttttgatt ttaataattt tgttaagaca
     9901 cttttattat ggtatacgaa aaatccactc agctgtctga gtggattagg tgtatttaga
     9961 ctcttagtct ttattttcgt atggcaagat caagttcaag atgattcctg tcatggctga
    10021 aagggcagta cctgaaagtg taactggacc aagtttaagg atagctcctc caagtccaag
    10081 aaccaacata gcacttgcga tgatgaggtt tcgcatttga gcgaaatcaa cacgttcttt
    10141 aatcaagact ttcaaaccat tgctggcgat aaccccatag agaaggattg acataccacc
    10201 aagtacagcg tttggaatag ttgaaatcaa ggcagtgaat ttaccaagga agctgagggc
    10261 aatcgcgatg aaggcagcgt tacggataac tgagacagaa gcgatacgag tcataccgat
    10321 aacccctgta ttttctccgt aagttgtatt ggctggtcca ccaaggaagg cagaaacaga
    10381 agttgcgata ccgtcaccaa gaagagtacg gtgaagacct ggttctttta agaattgacg
    10441 accacagatt tgacccaaaa cagtatggtc tccgatatgt tcagaaattg ttacgatagc
    10501 gattggcaag atagcgatgg cttctggacc aaagtaaaga ttgtactctt taaaggcacc
    10561 acctgtgcta aatggcaagt agaaaccagg aatttcgaac cagttggctt taagaactgg
    10621 tgtaaagtca accaagccaa gagttagtgc gaaaaggtaa ccaccgataa tggcaaagag
    10681 gaatggaatg attcgtagga agccttttcc ttttgtattg ataaaggcag caattaggaa
    10741 agtaacaacg gctaccagag catttttcca atttccgtct gctacaagac ctgcattggt
    10801 aacagctgaa cctgcaagtc caagaccgat aacgatgatc ataggaccga taatgattgg
    10861 tggcaagagt ttatcaatcc attttgttcc tacaaatcgg atgctggtag caacaaggac
    10921 atagaccaaa ccagtcaaga taacccctgt ttgggcagca gatacatccc cccccatttc
    10981 tttcatagcc agtgacatag ctgtgataaa ggcaaatgaa gaacctagat aaactggaac
    11041 tttaaaacca gtagcaatca tgtagatgag tgttccaaca cctgaagcaa aaagggcaac
    11101 agatacaggc attcccaaaa tcaatggtac caagatggtc gcaccaaaca tggcgaaaac
    11161 gtgttggaaa ctaaggagaa ttccttttcc agccgaagga cgttggtcaa cgtctagtaa
    11221 caaatcaaca gttgattctt gtttcatata aacctcactt ttgggcatca aaaaagagcc
    11281 cattatttta cagcaatagg ccctcagagt aagacttctt taaaatttag attttaaaga
    11341 gttttaaata tttctgcgtc ttcgtcacct cacgggatga cattaaaaac ctttgcttag
    11401 gatagtatag cagaaaaaaa tgattttgta aatcattttt tcccgagcct agaaataaaa
    11461 gagcgaggct gattttgtaa atcatttttt cccgagccta gaaataaaag agcgaggctg
    11521 attttgtaaa catttgttta ctaaaaaatt taaagtgggc gtttatttgg cataccagcc
    11581 ttacgcggat atttatttgg tgtttctttt ttcttttcta ccactgtgat atagcgcgga
    11641 tctctattcg gtagggcgta gctgagattg tcttcgacct tactaaaaag gagattgagg
    11701 gcattcttag cttctaataa ttcctcaggc gcattgctgg ccttgagtgc caatagtttt
    11761 ccaccaacct taaggtaggg aatggtcaat tcagatagga cctgcatacg ggcaaccgca
    11821 cgagctgtta caaaatcata ttgagcacgg aagttcttgt cttgggcaaa atcttcggca
    11881 cgtccgtggt agaaatgaac tccgttcaaa tccagttctt gagccaagag ttgtaggaag
    11941 ttgatgcgct tattgagtga atcaataatg gtcacatcta actccggata gagaattttc
    12001 attggtagac taggaaatcc tgccccagcc ccgatatcaa gaagtttgat agtttcattg
    12061 ggaatcaaac cttgaagaat gggtgcaatc gaatcgtaaa aatgtttgag ataaacttct
    12121 tccttgtccg taatcgccgt caaattaatc ttctcattcc actcgaccaa gagctcaaaa
    12181 taacgttcaa attgttcttt ttgctggtcc gaaagtggaa gattctgctc ggcaagcaag
    12241 ttgtaaaatg tttttggttt catagttatt tccttcttta gtatcatctt attttaccac
    12301 aatcatagaa aatttgatat actggtacta atctaaaagc agaaaggact tatattatga
    12361 cttggattat tcttggagtt atcgctctta ttgttatttt tgtgattgtt agctataacg
    12421 gtttggttaa aaatcgtatg caaaccaagg aggcttggag tcagattgat gttcagttga
    12481 aacgtcgaaa tgacctcttg ccaaacttga ttgagactgt aaaaggttat gccaaatatg
    12541 aaggttctac ccttgaaaag gtggcagaac tacgtaacca agtggcggca gcgacttcac
    12601 cagcagaagc tatgaaagcc agtgatgccc tcactcgtca ggtttcaggt atttttgcag
    12661 ttgcagaaag ctatccagat ttgaaagcta gtgctaactt tgttaaattg caagaggagt
    12721 tgacaaacac agaaaataaa atttcttact ctcgtcaact ctataacagt gttgtcagca
    12781 actacaatgt aaaattagaa actttcccga gcaatattat cgctggaatg tttggattta
    12841 aagcggcaga tttccttcaa acatctgaag aggaaaagtc ggttcctaaa gttgatttta
    12901 gcggtttagg tgactaagat gttgtttgat caaattgcaa gcaataaacg aaaaacctgg
    12961 attttgttgc tggtattttt cctactctta gctcttgttg gttatgcggt tggttatctc
    13021 tttataagat ctggacttgg tggtttggtt atcgcactga ttatcggctt tatctacgct
    13081 ttgtctatga tttttcaatc gacagagatt gtcatgtcca tgaatggagc gcgtgaggtg
    13141 gatgagcaaa cggcaccaga cctctaccat gtagtggaag atatggctct ggtcgctcag
    13201 attcctatgc cccgtgtttt catcattgat gatccagcct taaatgcctt tgcgacaggt
    13261 tctaatcctc aaaatgcggc tgttgctgcg acttcaggtc tactagctat catgaatcgt
    13321 gaagaactag aagctgttat gggacatgaa gtcagtcata ttcgtaatta tgatatccgt
    13381 atttcgacta ttgcagttgc ccttgctagt gctatcacca tgctttctag tatggcaggt
    13441 cgtatgatgt ggtggggtgg agcaggtcgc agacgaagtg atgatgaccg agatggaaat
    13501 ggtcttgaaa tcattatgct agtggtttcc ctactagcta ttgtactggc acctctcgct
    13561 gcaaccttgg ttcagctcgc tatttctcgt cagagggaat ttctggcaga tgcatctagt
    13621 gtcgagctga ctcgcaatcc ccagggaatg attaatgccc tagataagtt ggacaatagc
    13681 aaacctatga gtcgccacgt cgatgatgct agcagtgccc tttatatcaa tgatcctaag
    13741 aaaggtgggg ggttccaaaa actcttttat acccacccac ctatctcaga acggattgaa
    13801 cgtttaaaac agatgtaaaa gaatccagag gtcgtctctg gatttttgct atgttgcaaa
    13861 tttataaatc ttctaaatta actagcttca aaccgtgttc tgtcatgcga tagatgatcg
    13921 agcagacttc ttttaagaaa cgacggtcat gcgaaacagt gatgagaccg cctggatagg
    13981 ttgcaaagag ttttctgatt tggggttgag aagtgggaga aaagtttcgt gtgggttcat
    14041 ccagcaggag aaagtttggt ttgcgcagaa ctagatccaa aagcaggagt tttccctgtt
    14101 gtccgccaga taaggagcga atttgatgct gcatttctgg ataactgaaa ttgagactgg
    14161 ctaggtgaga ttggattttc tgaagttcct ctttttcccc agttttgctg atataagcta
    14221 ttgaggataa atccaattgc agttttttgt ggtaatcttg tggcataaaa ccaagtgaaa
    14281 tctctctttt atcattcaga agttgctgta atttggctaa cagagttgat ttcccaacac
    14341 catttgggcc gatgataccg attttttctt ggccacggac agttagttgc agttcctgag
    14401 ccaaaacacg gtcgtcaatg gacaaatttt ctttttccag ttggactaag actttagaag
    14461 ctggtaatgg ttggatgtct gaaaagaaaa gttggatttg ttcctcttca agtggctttt
    14521 gagtcatgga ctgagctgtc ttttcgtagc gtttttcttg tgagaggaca gttttcatct
    14581 ttttagccaa taggcgaccg gcagtactat ctttggtagc tcgaagcgca gtttctacat
    14641 tttgcttaac tctccgatgt ttttccatgg ttttatcgta ggctctttgg ttgttagcag
    14701 cttgctgact ttgtttggca aaattagcct ttctctgctc actatagcta tcatagtcta
    14761 aatgctctac tagcgtttcc gcttctttac ggtgtttgac cagtcgcaag tgaacaatag
    14821 tgtctgccgt ttcagaaaga aagtcttcat catgggaaat gaaaataacg gtttgcctgg
    14881 tcttttgaat ctggcctttt agccaatcaa ctgtctcaag gtctaggtca tttgaaggtt
    14941 catctaaaaa tagaatctca aagggtttgg ctaactcatg gataagctga attttcaaag
    15001 cttcgccccc tgatagattg ccaatctctt ggtcacttgc gaaacgattg ctatcaaaat
    15061 gcaattcctc cgccaaacga tagaggatac tgtagtctaa atcaatagaa tctaaaaaga
    15121 agtagtcgtg taaagttttc ttttttaggt cctcagggac tttttgagga atgtaggcca
    15181 gtgactgata atcagactgg atgtctccct tgatagtgaa atcagacaaa tcttccccca
    15241 ttaaagtttt aagtaaggtt gatttaccat ttccttcttc gccaataata gctacctttt
    15301 ccccgtcttg tatggtcatg cttaggtcag agacaaggtc tcgtaaatct ttgttttgtg
    15361 tgatggtcag gtgattgatt tttatcatac tattgccctt tctagaatgt cgatagtgca
    15421 taacaaaaag ctctacttta cctagtagag cccaaagtct atgtcaaaaa aactctatta
    15481 acatgccaga aaaagagcat aaaagagcac acaaaaagag acaaaaacaa gatctactaa
    15541 ataaaggttc tttatttgat agacttagtt gttcatgtct cccttacctc cgagtattag
    15601 tatctttata ctatactttt aaggaaattt tgtcaacaga aaactggaaa ttctatgctc
    15661 taaaatccaa aaacaggtcc atagagactt agtacgtgtt tgacatgctc gtaatggatt
    15721 ttatcatagt ttcgccaagc agtgcgtgct tgatcgttta gttttaggct acccagtcca
    15781 atcagaggac tggtgggttg gtaaaatttc tcaagatcaa ttaagatact gttgttcaac
    15841 ttttccgttt ttttgagctc ttgcatagta gtgtttagca gctcttgtag tcgaatatca
    15901 tctgccgtac cctgtttaca gttttggtag cttttattta acttggatag gagttgaatg
    15961 agtttcttgt cttccatgtc ttccatatga gcatcctcct tgatctgatg tactctttcc
    16021 ctatagtata gcactaaaaa ataaaactgt catagtaaat atgttaaaat tttgaatttt
    16081 aattacaaag tttggtgtgc tgatttgtag ccttttcatg gtataatcaa gagagtaaat
    16141 ctttatggag gaagtatgaa attaaatatt caagaaattc gtaagcagtc tgaaggtttg
    16201 aactttgaac aaacgttaga tttagttgat gacctgcgtg cacgtaatca agaaatttta
    16261 gatgtaaaag atatccttgc agttgggaaa gtacaatatg aagaccgtat gtatttctta
    16321 gattatcaac tatcttatac cattgttctt gcttcgagtc gcagtatgga gccagttgag
    16381 ttagttgaat cttatccagt cacggaagtt ttcatggaag gcgcaactaa ccagctagat
    16441 caagaagttt tagatgatga cttggtcttg cccattgaaa atggggagct tgaccttgct
    16501 gagagtgtat cagacaatat cctgctaaac attcctatca aggtcttgac ggctgaagaa
    16561 gaagctggtc aaggatttat ctcaggaaat gactggcaaa tcatgacaga ggaagaatac
    16621 caagctcaac aagcagtaaa gaaagaagaa aacagtcctt ttgctggctt acaaggacta
    16681 tttgacggag atgaataatg gtcttgtcaa aaaaacgagc acgaaaggtg ctagaagaaa
    16741 tcattgccct cttcccagat gccaagccta gtcttgattt taccaatcat tttgaactcc
    16801 tggttgcggt catgttatca gcccagacga cagatgcagc ggtaaataag gccacaccag
    16861 gtctctttgt tgcctttcca acaccccaag ctatgtctgt agcgacagag agtgagattg
    16921 cttcacatat ttctcgcttg ggattgtatc ggaataaagc taaattcctt aaaaaatgtg
    16981 cccaacagtt actagacgat tttgatggtc aagtccctca gacacgtgaa gaattggaga
    17041 gtttggcagg tgttggtcgc aagacagcca atgttgtcat gagtgtagga tttgggattc
    17101 cagcctttgc agtggatact catgtggagc gtatttgcaa acaccacgat attgtcaaaa
    17161 aatcagcgac gccacttgag gtggaaaagc gggtcatgga tatcttgccg cctgagcagt
    17221 ggttagctgc ccatcaggcc atgatttatt ttggaagagc catttgccat ccaaaaaatc
    17281 cagagtgtga ccagtaccca caattatatg attttagcaa tttgtaagat gctacattga
    17341 aactttttgc ttgattttaa gcatgctttg tgctatagta aatgataact aaatattcct
    17401 ttaaacctgt cccgtgaggc aggcaaggag cgcgataaag tagaagggtg aagtctatac
    17461 tgtttgcagt agggctcgct tggctataaa tttcaagtct ccttgtttaa ggagactttt
    17521 ctttttggag gtttgtcatg aaaacaaaag aagttgtaga cgaattgacc gtcaaacgag
    17581 cgattacgcg tattacttat gagattatcg aacgcaacaa agatttgaat aagatcgtct
    17641 tggctggtat taaaactcgt ggtgtcttta ttgcccaccg aatccaagaa cgtttgaagc
    17701 agttagaaaa tctttcagtt cctgttgtgg aattggatac taaacctttc cgtgatgatg
    17761 ttaaaagtgg agaagatact tctttggttt ctgtcgatgt gacagaccgc gaagttatct
    17821 tggtggatga tgtgctctat acaggtcgta ccatccgtgc tgctattgat aatattgtcg
    17881 gtcatggtcg tcctgcgcgt gtgagtttag cagttctagt cgatcgtgga catagagaat
    17941 tgccaatccg tccagattac gttggaaaaa atatcccaac cagtcgttct gaagaaatca
    18001 tcgtagagat gacagaactt gatgaccaag acagagttct gattactgaa gaagcttaga
    18061 aagttaaagg agtagccatg tcagaaaatc aacaagcatt gaaccatgtg gtgtccatgg
    18121 aagacctcac tgtcgatcaa gtaatgaaat tgatcaagcg aggaattgag tttaaaaatg
    18181 gagcccagct tccctatgaa gaccatccga ttgtttccaa tctcttcttt gaggattcta
    18241 cacggacaca taagtccttt gaagtcgcag agattaaact tggattggaa cgacttgact
    18301 ttgatgtgaa gactagttcg gttaataagg gtgagacact ttatgacacc attttgactc
    18361 tgtctgcttt aggagtggat gtctgtgtga ttcgccatcc agaggtcgac tactatagag
    18421 aattgattgc tagtccaacg attacgactt ccatcatcaa tggtggagat ggttcgggcc
    18481 aacaccctag ccagagcttg cttgatttga tgaccattta tgaggaattt ggccactttg
    18541 agggtcttaa agttgctatt gcaggtgact tggaccactc acgcgttgcc aaatccaata
    18601 tgcagatttt gaaacgcttg ggagctgaac tctttttcgc tggacctgag gaatggagaa
    18661 gtcaagagtt tgcagactat ggaaagtttg taaccattga tgaaatcatt gatcaggttg
    18721 atgtcatgat gtttctccgt gtgcaacacg aacgccatga tagtggagct gtattttcaa
    18781 aagaagacta tcatgcccaa catggcttga ctcaagaacg ttacgatcgt ttgaaagaaa
    18841 cagcaatcct catgcaccca gctccaatca atcgtgatgt agaaatagca gaccacttgg
    18901 ttgaagcacc aaaatcacgg attgtccaac aaatgaccaa tggtgtcttt gttcgaatgg
    18961 caatcttaga atccgtacta gcgagtagaa acgccaacta aaacacaaga cgttaaaaga
    19021 cgccagtgag cgtccacgag aggtgaaaat atgacaaaaa gaattctagt attagaagat
    19081 ggcacagttt ttgaaggcaa ggccttcgga gcagatattg atgtaacagg cgaaatcgtc
    19141 tttaatacag ggatgaccgg ctaccaagaa tccattacag accagtctta taatggacaa
    19201 atcttgacct ttacttatcc tttggtagga aattatggta ttaatcgtga tgattatgaa
    19261 tccattattc caacttgtaa gggagtcgtt gtttttgaag aagcgcgtag agctagcaac
    19321 tggcgcaacc aaatgacctt ggatgaattt ttgaaagcca agaaaattcc agggatttca
    19381 ggaattgata cgcgtgctct taccaagatt atccgtaagc atggtactat gcgtgcaacc
    19441 ttgacccatg ttggggacag tatggaccat gtgacggacc agctccaagc aacagtttta
    19501 ccgacagaca atatcaaaca ggtttctact aaaacgtctt atccagctcc aggagttggt
    19561 ttgagcgtgg tgctagtgga ctttggtctc aagcactcaa tcctacgtga actttctaaa
    19621 cgcaactgta acgtgacagt tgttccttat tcgacaacgg ctgaagaaat tctccatctc
    19681 aatcctgatg gagttatgtt gtcaaatggt ccaggtaacc cagaagacgt tccacaagca
    19741 ctcgacatga ttcgcggtgt acaaggaaaa attccaatct ttggtatttg tatgggacac
    19801 caactctttg caatggcaaa cggggctaag acctataaga tgaagtttgg ccaccgtgga
    19861 ttcaaccatg cggtacgtga aatcgcaaca ggacgagtag acttcaccag ccagaaccat
    19921 ggttatgcag tcagccgcga ggatttgcca gagcacttga ttattaccca cgaagaaatc
    19981 aatgacaagt cagtggaagg tgtgcgccac agataccaac ctgctttctc tgttcaatac
    20041 cacccagatg cagctcctgg gccacacgac gctagctacc tatttgacga gtttatcgag
    20101 atgatggaag tttttaaaca atcaaactaa gaatgagtaa aagctcgtcg gagaatttat
    20161 gtaactgaac atggacggaa agctcagaat ttagagaaac caacttggat tgtcaatcct
    20221 tccttgattt cctaaaattc aatcgctttc tagtcgtcct ttgtatctta tttaatgtcg
    20281 ccctgagagg cgacgaatag aaaggagaag atacattgtt cgcggaagtg aacacgccct
    20341 aagaactgtg tgaaaaagat aaacatcgtc ttgacgctga aggcgtctgc gccgagtttc
    20401 ctattttcac tgtgttcttt acgggctttg tatcataaac tatgcctaaa cgtactgata
    20461 ttcaaaaaat tatggtgatt ggttctggtc cgattattat tggtcaggct gctgagtttg
    20521 actacgctgg gactcaggct tgcttgtcgt tgaaagagga aggttatgag gttgttttgg
    20581 ttaactcaaa tcctgcaacc atcatgacgg acaaggaaat tgctgacaag gtttacattg
    20641 aaccgattac acttgagttt gtgacacgta ttcttcgtaa ggaacgtcca gatgccttgc
    20701 taccaacact cggtggtcag acaggtctca acatggccat ggaattgtct aaaaatggta
    20761 tcttagatga gcttggcgtt gaacttctgg gtaccaaatt atctgccatt gaccaagcgg
    20821 aggaccgtga cctctttaaa caattgatgg aagagcttga acaacccatt ccagaatctg
    20881 aaattgttaa cacagtagaa gaagcagttg cctttgcagc gacaattggc tacccagtca
    20941 tcgttcgtcc agcctttacc ctcggtggta ctggtggtgg tatgtgtgcc aacgagaaag
    21001 aattgcgtga aatcactgaa aatggtttga aattgtcacc tgttacccaa tgtttgattg
    21061 agcgttcgat tgccggtttc aaggaaattg aatacgaagt gatgcgtgac tcagctgaca
    21121 atgccttggt tgtttgtaac atggaaaact ttgacccagt tgggattcac acgggggatt
    21181 ccattgtatt tgcccctgcg caaaccatgt cagactatga aaaccaaatg cttcgtgatg
    21241 cgagcttgag cattattcgt gccctcaaga ttgaaggtgg atgtaatgtt cagctagctc
    21301 ttgatcctaa cagcttcaag tattatgtta tcgaagtaaa ccctcgtgta tcacgttcgt
    21361 cagcccttgc ttctaaagcg acaggatatc cgattgctaa gttggctgcc aagattgcag
    21421 taggtttgac cttggatgag gttataaacc cagttacagg ttcaacctat gccatgtttg
    21481 aaccagccct tgactacgta gttgctaaga ttccacgttt cccatttgac aagtttgaaa
    21541 agggtgaacg ccgtctcggt acacaaatga aggcgactgg agaagtcatg gcaatcggtc
    21601 gtaacatcga ggaatctctt ctcaaggcct gccgctccct tgaaattggg gtgcaccaca
    21661 atgaaatacc tgaacttgca gcagtttctg atgatgcctt gattgaaaag gttgtcaaag
    21721 cccaagatga ccgtctcttc tacgtatcag aagcaattcg tcgtggctac acacctgaag
    21781 aaattgcaga gcttacaaaa attgatatct tctatcttga taaactcttg catatctttg
    21841 aaattgagca agaattgggt gctcatccac aagatctaga agttttgaaa acagccaaac
    21901 ttaatggttt ttcagaccgt aagattgctg aactctgggg aacgactgat gatcaagttc
    21961 gccaacttcg cttggaaaac aagattgttc cagtttataa gatggtagac acttgtgcgg
    22021 cagagttcga ctccgaaacg ccatatttct attcaaccta tggttgggaa aatgaatcta
    22081 tcagatctga taaagaatct gtacttgtcc taggttcagg tccaatccgt attggtcaag
    22141 gggttgagtt tgactacgca accgttcact ctgttaaggc tatccaggca gctggttatg
    22201 aagctatcat catgaactca aacccagaga ccgtttcaac agacttctct gtatcagata
    22261 agctttactt tgagccattg acattcgaag atgttatgaa cgtcattgac ttggaacaac
    22321 caaagggagt tatcgttcag ttcggtggtc aaacagccat caaccttgcg gagccattgg
    22381 caaaagcagg tgtgaccatc cttggtacac aggttgctga cctagatcgt gccgaagacc
    22441 gtgacctctt cgagcaagct ctcaaagaat tggatattcc acagccacca ggacaaacag
    22501 ctaccaatga agaagaagca gctcttgcag ctcgcaagat tggcttccca gttcttgtcc
    22561 gcccatctta tgtacttggt ggacgtgcca tggaaatcgt tgaaaacgaa gaagaccttc
    22621 gttcttacat gcgaactgct gttaaggcta gtccagacca cccagttctt gtcgactctt
    22681 atatcgttgg gcaagagtgc gaagttgatg ccatttcaga tggtaaaaat gtactcattc
    22741 ctggtatcat ggagcatatc gaacgtgctg gtgtccactc aggtgactca atggctgttt
    22801 acccaccaca aaccttgtcg caaaaggttc aggagaccat cgcagactac accaaacgct
    22861 tagcaatcgg tcttcactgc cttggaatga tgaacatcca gtttgttatc aaggatgaaa
    22921 aagtctacgt tattgaggtc aatccacgtg ccagccgtac tgttccattc ctatctaagg
    22981 taaccaatat tcctatggct caagtagcga ccaaactcat tcttggtcaa agtttatcag
    23041 aacttggcta ccaaaatgga ctttaccctg aaagcacccg tgttcatatc aaggcacctg
    23101 tcttctcctt taccaaacta gctaaggtag acagcttgct cggtcctgaa atgaagtcaa
    23161 caggtgaagt tatgggttct gatgctactt tggaaaaagc tctctataaa gcctttgaag
    23221 cttcttatct acacttgcca acttttggta atgtcgtctt taccatcgct gatgatgcca
    23281 aagaagaagc cttgaacttg gctcgtcgtt tccaaaacat tggttatgga atccttgcga
    23341 cagaagggac agcagccttc tttgctagcc atggcttgca agcccaacct gttggtaaga
    23401 ttggtgatga cgataaggat atcccaagtt ttgtacgcaa aggaagaatt caagctatca
    23461 ttaacacagt aggaacaaaa cgaactgctg acgaagatgg tgagcaaatt cgtcgttcag
    23521 ccattgaaca cggggtgccc ctcttcacag cgctagatac agctaatgcc atgcttaagg
    23581 tacttgaaag tcgtagcttt gttacagaag cgatttaaat agaaaaataa gatatagcag
    23641 actgaattta gaacagtaca caggaatact aaaatatttc tagaaattaa tttgaatttt
    23701 ctaattgatt tgttcgcatc ttatttcaat ctactataga aaaaagtctt taaaattata
    23761 aaacgcatca tatcaaggtt tttcaaaaac cttgatatga tgcgttttat tgtgggaata
    23821 tgtatttcat tttctactaa aattatgttt ttgaataacc tctatcttag tagtttgtat
    23881 aatccccctc aatcagtttt tgcgataagc tttaatgcta tgactatacc actcttgcat
    23941 ttcttttgat ggtggtgtca tataatcgcc atacatctgg gttaaaaatt ggtcatattt
    24001 tttgggaaca ggcaacatac ggccctcaaa ctcagttaaa atcagttctt taaaggtatc
    24061 aactgggaag atttctttca tcccttcctt accgatccca actcctcctt catattgagg
    24121 aatgttggtt acagcatttt tgactagttg atcaattttc ttgtaaaagt agcgaggatt
    24181 gacaaatcgg agagcgtacc agctacataa tctaagaaaa tcttttagtt tgctatcacc
    24241 gtgaactgct cgtgattttt tgatgtaagc tagttgacga agggccacat acttatagct
    24301 cttgtcgaca atgctcaagt ctgtaaattg atcaattggg aagacatcga tgaaaaggct
    24361 ggtatcatga cgcttgtact taacatggtc ttctataaca gtagaagtat ccaaaatcga
    24421 tgcgaaatta tggaagtacc aagaagatgt atcgtaggaa agaaccttgt agcgagggtg
    24481 attttcttct tcaataatct tcagtaaacg ctcataatcc tcacgataaa gggaaatatc
    24541 aatatcatca tcccaaggaa tcataccttt gtggcggatg gctccaagca tggttccata
    24601 actgagaaaa taaggaatat catgtttctt acaagtctca tcaatatagt ccagcagggc
    24661 tagttgaatt tctttaattt cttttttttc taaatattgc atcctaatcc tccaatttat
    24721 aagcgtgaaa ttcatgactg tagaagcgtt tttcttctgg tggtagggtc atataatctc
    24781 cataaaattg tgtcaaaata gtatcaaatt tttcaggtgc aggaaggctt aaattctcaa
    24841 agggtaaatc gattgtttta tcaaaggtag cacttgggaa gacttccttt tccttaaatt
    24901 ttgaaggaat aaaagccata tactgcccat tttcacgact atatttttga atttctttct
    24961 cgattttatt tgcaaaataa cgaggagaaa ccagtcgaag gagcaaccaa aaggctgttc
    25021 gtatccaatc ttttaaaagg ctatccttat agacaatatt tttatgttta ctgaaagaca
    25081 gcagtttgaa gctttctagt ttataacaag tatcaatgac cttaggatca tcaaagcgat
    25141 ccatagggaa aatatcgata aagataccag actcataggt ttttgtattt cgagtatcaa
    25201 taattttagt cgtactgtcg gttatcttga taaagttgtt aaagtagttc ttatcagttt
    25261 ctaaggatag gagcttatac ttgctttttt ccttttgaaa aatgttaata aatcgttggt
    25321 agtcttctct aggcatggat aaatcaatat cgtcgtccca agggataaag ccctcatgtc
    25381 gaaccgcccc aatcagagta ccgtagttaa taatatagtt gatattgtgc tttttacaga
    25441 gagtatcaat ataattcaaa atttctaatt caatttgttt ggcatcttca acggttagtt
    25501 gtttcatttt aaactcctaa gattttttaa atttattttt taaggctagg acatggttta
    25561 aaaattcata gaaaatgcta tcttttgtga agacaagtag actaatataa gagatagctg
    25621 atagcaagac aatcaaacca gtattaatca aaaatggcaa attaatgacc atatccacag
    25681 gatacacgaa attaatcagg aaataaattg ctacaaagga aagtgaaaag agagagtatc
    25741 gaacagtata gctaaagata tgtcccaagt ggatgagttg ttttctatgg atgaaaatga
    25801 tatagaaaac aagtagagaa gcctctgata acatagttgt cagtaagtag tattcgggag
    25861 ccacgatatg gttgaaaaag aggagactat tcaagcccaa attgagtagc ccagcaaaga
    25921 ctgtatagac tgtgatacgt ttttcatagc cattggtaaa gagaatttgg gaaccaagaa
    25981 tggtatctaa ggccaggata atcgtacgaa aagcgaagag agaggtcaag atgtcgcctc
    26041 cgatatattt ttcactaccg taaagtagga tggcatttgg tcctaaaacc atgagtccaa
    26101 aactcagtgg aatgataaag aagttaaaga ttcgactacc tctattaacc agagaaacat
    26161 aggcttcttt gtctcctttc cccagatagt aactgagacg aggcacactc actccaattg
    26221 cacctgttac aaccccagct ataacggtca caattcgctg agctatggta tagtaactaa
    26281 cgttgacatc aatccctgtt ttaacgagga agaggcgatc taaaaaagtg aagagcatat
    26341 tggcattggc aaagactaac atggctgtca gagggagaaa gagtggttta aaatcactta
    26401 ggtgaatctt aacaagtttg atgtctcttt taatccaaaa ataactaatc aggtagttaa
    26461 tcagcgtcga taaactcatc acaagtgtat agacaacaat atcgtgttca tttttaacaa
    26521 ataagaaaat agagaccagc atcaggatac ggatgaaggc agttttgtaa aagagaaaac
    26581 tgtaattttc cagagcttca ttgacccatt cgattgaaaa aatctgggca atgagttgaa
    26641 tccccataac aaggtagacc tttttgacga ttggattatc agtaaagaag agaggatagg
    26701 ctaggatata gacagcagtg gtcaaaatcg tacaagcgat gcacaaataa aaaagactag
    26761 aaaaggttct gttaagatct tttttgttat ccttgacatt actgatagcc cttaaaccgt
    26821 agttatagac accataagtt gcaaagggca agaaaaatga caaaatagtg tcgactgagt
    26881 tgaagtaacc atagtcagtt cggtccaaga cacgcgcgac ataggttcca gttaggatgg
    26941 gaaaaataat attcaagaca cgaattccca tgtaagatag agcatttaat tttatacttt
    27001 tcattcaatt tacctcgttt ttcattatat cataaagtta gctaataaga aatgaagggc
    27061 agtaagtcaa gtaatcactt tgaagtttca aatcttaagt tttaagtttt ctttaaggaa
    27121 agtatattat tctgaaggac tctaaaattt cgcagccatt tattagtaat tgctacagaa
    27181 ttcctagtca ttactagaaa tggactagtt tctttgaata atagaactgc ataattctcc
    27241 tattctagaa ggggaggacc agtatttctt ttatgatagg actagattgt ggtataatag
    27301 agagaataag tttttttagt aagacaaagg agaaaataga tgatttatgc aggaattctt
    27361 gccggtggaa ctggcacacg catggggatc agtaacttgc caaaacaatt tttagagcta
    27421 ggtgatcgac ctattttgat tcatacaatt gaaaaatttg tcttggagcc aagtattgaa
    27481 aaaattgtag ttggtgttca tggagactgg gtttctcatg cagaagatct tgtagataaa
    27541 tatcttcctc tttataagga acgtatcatc attacaaagg gtggtgctga ccgcaataca
    27601 agtattaaga aaatcattga agccattgat gcttatcgtc cgcttactcc agaggatatc
    27661 gttgttaccc acgattctgt tcgtccattt attacacttc gcatgattca ggacagtatc
    27721 caacttgccc aaaatcatga cgcagtggac acagtggtag aagcggttga tactatcgtt
    27781 gaaagtacca atggtcaatt tattacagat attccaaatc gtgctcacct ttatcaagga
    27841 caaacacctc aaacattccg ttgcaaggac ttcatggacc tttatggatc tctttctgat
    27901 gaagagaagg aaatcttgac agatgcatgt aaaatctttg tgatcaaagg aaaagatgtg
    27961 gccttggcca aaggtgaata ctcaaatctg aagattacaa ccgtaacaga tttgaagatt
    28021 gcaaaaagta tgattgagaa agactagtaa aatgattaat caaatttatc aactaactaa
    28081 gcctaagttt atcaatgtca aatatcagga agaggctatt gaccaagaga atcatatcct
    28141 tatccgtccc aactacatgg ctgtctgtca tgcggatcag cgttactatc agggaaaacg
    28201 tgatcccaag attttgaata aaaagcttcc aatggcaatg attcacgagt catgtggaac
    28261 cgtcatttct gacccgaccg gaacctacga ggttggtcaa aaagttgtca tgattcccaa
    28321 tcagtctcct atgcagagtg atgaagaatt ctatgaaaac tacatgacag ggacccattt
    28381 cttgtctagt ggatttgatg gctttatgag agagtttgtt tctctcccta aagatcgtgt
    28441 ggtggcttat gatgctattg aagatacggt tgcagccatt acagagtttg tcagtgtggg
    28501 catgcacgct atgaatcgtc tattgactct tgctcatagc aagcgggagc ggatcgccgt
    28561 tattggagat ggaagtttag cttttgtggt tgccaatatt atcaactata ctttgccaga
    28621 agcagagatt gtggttattg gtcgtcattg ggaaaagttg gaactcttct catttgccaa
    28681 agaatgctat attacggata atattcctga agagttggcc tttgaccatg cttttgaatg
    28741 ttgtggtggt gatggtactg gaccagctat taatgacttg attcgctaca ttcgtcctca
    28801 gggaacgatt ctcatgatgg gagttagcga atataaagtc aatctcaata ctcgcgatgc
    28861 cttagaaaag ggcttgattt tggttgggtc atctcgttct ggtcgcattg attttaaaaa
    28921 tgctatccaa atgatggaag tcaagaaatt tgccaatcgt cttaaaaata tcctttatct
    28981 agaagaacct gtaagagaaa ttaaagatat tcatcgtgtc tttgcaaccg atttaaacac
    29041 agcctttaaa acagtgttta agtgggaagt ataagtactg gaggttaatt gtggagaaaa
    29101 tcattaaaga aaaaatttct tccttactta gtcaagaaga ggaagtcctc agtgttgaac
    29161 aactgggtgg aatgaccaat caaaactatt tggccaaaac aacaaataag caatacattg
    29221 ttaaattctt tggtaaaggg acagaaaagc ttatcaatcg acaagatgaa aagtacaatc
    29281 ttgaactact aaaggattta ggcttagatg taaaaaatta tctttttgat attgaagctg
    29341 gtatcaaagt aaatgagtat atcgaatctg cgattacgct tgattcaacg tcaatcaaga
    29401 ccaagttcga caaaattgct ccaatattac aaactattca tacgtctgct aaggaattaa
    29461 gaggagaatt tgctcctttt gaagaaatca aaaaatacga atccttgatt gaagaacaaa
    29521 ttccttatgc caactatgaa tctgttagaa atgcagtctt ctccttagag aaaagactgg
    29581 ctgacttagg tgttgacaga aaatcttgtc atatcgattt ggtgcctgaa aactttatcg
    29641 aatcacctca aggacgactt tatttgattg actgggaata ttcatcaatg aatgatccaa
    29701 tgtgggattt ggctgccctc tttttagagt ctgaattcac ttcccaagag gaagaaactt
    29761 tcttatctca ctatgagagt gaccaaacac cggtttctca tgaaaagatt gctatttata
    29821 aaattttaca agatactatt tggagtctat ggactgtcta taaggaagag caaggtgaag
    29881 attttggtga ctatggtgtg aatcgttacc aaagagctgt taaaggtttg gcttcttatg
    29941 gaggttcaga tgaaaagtaa aaacggagtt ccttttggcc ttctctcagg tattttctgg
    30001 ggcttgggtc taacggttag tgcttatatc ttttcgattt ttacagattt gtcacccttt
    30061 gtggtggctg cagctcatga ttttttgagc atctttatct tactagcttt tctcttggta
    30121 aaagaaggga aagttcgcct ctcaattttc ttaaatattc gcaatgtcag tgttatcatc
    30181 ggagccttgc tagcaggccc tatcggtatg caggccaatc tttatgcagt taagtatatc
    30241 ggaagttctt tagcttcatc tgtatcggct atttaccctg cgatttcagt tctattggct
    30301 ttcttctttt tgaagcacaa gatttcgaaa aatactgtat ttgggattgt cttgattatt
    30361 ggagggatta ttgcccagac ctataaagtt gaacaggtta attctttcta cattgggatt
    30421 ctttgtgctt tggtttgtgc tattgcatgg ggaagtgaga gtgttcttag ctcttttgcc
    30481 atggaaagtg aattgagtga aatcgaagcc ctcttaatcc gtcaagtaac ttcgttcttg
    30541 tcctatcttg tgattgtgct cttctctcat cagtcattta ctgcagtagc caatggacaa
    30601 ttgctaggtc tcatgattgt ttttgcagcc tttgatatga tttcctactt ggcttattat
    30661 atcgctatca atcgcttgca accagccaag gctacaggct tgaacgtgag ctatgtagta
    30721 tggacggtct tgtttgcagt tgttttcttg ggtgcaccgc tagatatgct gaccattatg
    30781 acgtcacttg tcgtcattgc tggagtttat attattatta aagaataaag gagattcgtg
    30841 tgaaagccat catcttagca gcgggattgg gaactcgctt gcgtcctatg actgaaaata
    30901 cccctaaagc cttggttcag gttaatcaaa aacctttgat tgagtaccaa attgagtttc
    30961 tcaaagaaaa aggaatcaat gacatcatca tcattgttgg ttatcttaaa gaacaattcg
    31021 attacttgaa agagaaatac ggtgttcgtc tcgttttcaa tgataaatac gctgactaca
    31081 ataactttta ctctctctat cttgtaaaag aagaattagc caatagttat gttatcgatg
    31141 ccgataacta tctctttaaa aatatgttcc gcaatgattt gacacgttct acttatttta
    31201 gtgtctatcg tgaagattgt accaacgaat ggttcttggt ctatggagat gactacaagg
    31261 ttcaaaacat tattgttgat agcaaggcag gtcgcatcct tagtggtgta tccttctggg
    31321 atgctccaac agcagaaaaa attgttagct ttatcgataa ggcttatgca agcggcgaat
    31381 ttgttgatct ctattgggac aatatggtta aggataacat caaagagcta gatgtctatg
    31441 ttgaagaatt agaaggcaat agcatttatg agattgatag tgtccaagac tatcataaat
    31501 tagaagaaat tcttaaaaac gaaaattaaa agcttccaac atctgacaaa atagtcggat
    31561 gtttttttga ttttttacga acttttacga atagatagat gagtagaaaa agaaatggag
    31621 ttatttatga aaatcacaaa ctatgaaatc tataagttaa aaaaatcagg tttgaccaat
    31681 caacagattt tgaaagttct agaatacggt gaaaatgttg atcaggagct tttgttgggt
    31741 gatattgcag atatatcagg ttgccgtaat ccagccgttt ttatggaacg ttattttcag
    31801 atagacgatg cgcatttgtc gaaagagttt caaaaatttc catctttctc tattttagat
    31861 gactgttatc cttgggattt gagtgaaata tatgatgcgc ctgtactttt attttacaag
    31921 ggaaatcttg acctcctgaa attcccgaag gtagcggtcg tgggcagtcg tgcttgtagc
    31981 aaacagggag ctaaatcagt tgaaaaagtc attcaaggct tggaaaatga actggttatt
    32041 gtcagtggtc tggccaaggg cattgacaca gcagctcata tggcagctct tcagaatggc
    32101 ggaaaaacca ttgcagtgat tggaacagga ctggatgtgt tttatcctaa agccaataaa
    32161 cgcttgcaag actacatcgg caatgaccat ctggttctaa gtgaatatgg acctggcgaa
    32221 caacctctga aatttcattt tcctgcccgt aatcgcatca ttgctggact ttgtcgtggt
    32281 gtgattgtag cagaggctaa gatgcgttca ggtagtctca ttacgtgtga gcgagcaatg
    32341 gaagaaggac gcgatgtctt tgctattcct ggtagcattt tagatggact atcagacggt
    32401 tgccatcatt tgattcaaga aggagcaaaa ttggtcacca gtgggcaaga tgttcttgcg
    32461 gaatttgaat tttaaaaatg acctaagcta gaattctaag aaaaaatcaa ttttaagaga
    32521 aaatgaaccc aacatttcca taataaaacg catattagca agtttttaac acttgataat
    32581 atgcgttttt tctaagtgga ttagtagagt agaggatttt tctcatataa tactcttcga
    32641 aaatctcttc aaactacgtc agcttccatc tgcaacctca aaacagtatt ttgagctgac
    32701 ttcgtcagtc ttatctacaa cctcaaagca gtgctttgag caacctgtgg ctagcttcct
    32761 agtttgcgct ttgattttca ttgagtataa gggaaagtat agtgaattga aataagatgt
    32821 gaacaactct atcaggaaag tcaaattaat ttatagaaat attttagcag ccaaggtgca
    32881 ctgttataga ttcaatacac tataatttag tgtaattgag aaaggagaaa tgattgtgat
    32941 tgatgttggc taggttatgt tcaatgattc ctaccgtctc aaatcttgtc agtaaggaaa
    33001 aataaattct tcaaaagtag agattacaag gcttgtttaa gaaagaattc aaagaccttg
    33061 acaaataaaa ataaaatggt tattataaaa aatggtctga aatagatgat gatacttttc
    33121 gaaaatcttt ttacgtcagc tcagctttgc cttgctgtgt tttgagcaag ctacggttag
    33181 cttccgagtt tgattttcat ttactagaaa tgaaactgat gagagatatc agtagacatt
    33241 tgagtcagga tattatggaa aatgataaaa agagctcgtg agattggcat atcagactac
    33301 taaagtattg agtttgttag gattttagcg actagttagc tgggaaagga agatatttgt
    33361 gacaaataat aaactgtatt cgttgataga atttagaaat aaaatatatg aagaattaga
    33421 actttccaga agtgatttag cgattttact atgtgccatg cttatcgcct ctatcggatt
    33481 aaatatggat tcgactcccg tgattattgg agccatgtta atctctcctt tgatgacacc
    33541 tattctggga gtggggctct ctctagctat atttgatttt aaattgttaa gaaaatcttt
    33601 taaaatatta gctattcaaa ttcttgccag tttaatagct tcaacacttt atttttatct
    33661 ttctcccatt tcgtatgcta gttcggaaat tgttgctaga acctctccga ctatttggga
    33721 tgttctcatt gcttttgtag gagggatagc aggtattatt ggtgctagga aaaaagagac
    33781 caataatatt gttcctggtg ttgctattgc aaccgccttg atgcctcctc tttgtacagt
    33841 aggttatgct attgcttctg ctaatctaaa atttatcata ggctcctctt acctattcct
    33901 catcaattgt agctttattg tcattgcgac ttatataggt gttaggttga tgatggttaa
    33961 gaaacattat tttaaagata atgaagaaga ctctaaaatg cgtaggattt tgcttctagt
    34021 tgctgttttg ctgatgattc cgagtttcat ctctgcaacg actttagtga gagaaacgtt
    34081 gaaaaaagag tcccttaaga aatttatatc agagcagttt caggggcata atattttgaa
    34141 aaaaacctat tctaaaaaga ctcataccct aaagctaacc atttcaggaa attatttgac
    34201 agaagaagaa ctcgatatga tttcaagtaa gagaggtgac tatggtttaa gtgatgtttc
    34261 tgttcaagtt tcacaattgt ctgattcaga acaacttagt aaggaagaac tggtggagta
    34321 tttcttccag tatatcaagg ataaggaagc aaaagaaaag gaaaaagcta ataagtttta
    34381 tacagagtct gaggagcaat aatttcttga gaatagctgg tttctctcgt gagtcttcta
    34441 tgtatatcaa aggaagactg aggttttaag tataaaactt ttcttctatt atagtagcta
    34501 agtcttgaca gggttcaaaa aatggtttac actttataaa gtttattact ttgaaaaggt
    34561 gtgatactgt ggctacggca acaaaaaaga aaaaatcaac agttaaaaaa aatctagtca
    34621 tcgtggagtc gcctgctaag gccaagacga ttgaaaaata tctaggcaga aactacaagg
    34681 ttttagccag tgtcgggcat atccgtgatt tgaagaaatc cagtatgtcc gtcgatattg
    34741 aaaataatta tgaaccgcaa tatatcaata tccgaggaaa aggccctctt atcaatgact
    34801 tgaaaaaaga agctaaaaaa gctaataaag tttttctcgc gagtgacccg gaccgtgaag
    34861 gagaagcgat ttcttggcat ttggcccata ttctcaactt ggatgaaaat gatgccaacc
    34921 gtgtggtctt caatgaaatc accaaggatg cagtcaaaaa tgcttttaaa gaacctcgta
    34981 agatcgatat ggacttggtc gatgcccaac aagctcgtcg gatcttggat cgcttggtag
    35041 ggtattcgat ttcgcctatt ttgtggaaga aggtcaagaa gggcttgtca gcaggtcgcg
    35101 ttcagtccat tgcccttaaa ctcatcattg accgtgaaaa tgaaatcaat gccttccagc
    35161 cagaagaata ctggacagtt gatgctgtct ttaaaaaggg aaccaaacaa tttcatgctt
    35221 ccttctatgg agtagatggt aaaaagatga aactgaccag caatgacgaa gtcaaggaag
    35281 tcttgtctcg tctgactagt aaagactttt cagtagatca ggtggataag aaagagcgca
    35341 agcgcaatgc tcctttaccc tataccactt catctatgca gatggatgct gccaataaaa
    35401 tcaatttccg tactcgaaaa accatgatgg ttgcccaaca gctctatgaa ggaattaata
    35461 ttggttctgg tgttcaaggt ttgattacct atatgcgtac cgattcgact cgtatcagtc
    35521 ctgtagcgca aaatgaggcg gcaagcttca ttacggatcg ttttggtagc aagtattcta
    35581 agcacggtag caaggtcaaa aacgcatcag gtgctcagga tgcccatgag gctattcgtc
    35641 cgtcaagtgt ctttaataca ccagaaagca tcgctaagta tctggacaag gatcagctca
    35701 agctatatac ccttatctgg aatcgttttg tggctagcca gatgacagcg gccgtttttg
    35761 ataccatggc tgttaaattg tctcaaaatg gagttcaatt tgctgccaat ggtagtcagg
    35821 ttaagtttga tggttatctt gccatttata atgattctga caagaataag atgttaccgg
    35881 acatggttgt tggagatgtg gtcaaacagg tcaatagcaa accagagcaa catttcaccc
    35941 aaccgcctgc ccgttattct gaagcaacac tgattaaaac cttagaggaa aatggggttg
    36001 gacgtccatc aacctatgcg ccaaccattg aaaccattca gaaacgttat tatgttcgcc
    36061 tggcagccaa acgttttgaa ccgacagagt tgggagaaat tgtcaataag ctcatcgttg
    36121 aatatttccc agatatcgta aacgtgacct tcacagctga aatggaaggt aaactggatg
    36181 atgtcgaagt tggaaaagag cagtggcgac gggtcattga tgctttttac aaaccattct
    36241 ctaaagaagt tgccaaggct gaagaagaaa tggaaaaaat ccagattaag gatgaaccag
    36301 ctggatttga ctgtgaagtg tgtggcagtc caatggtcat taaacttggt cgttttggta
    36361 aattctacgc ttgtagcaat ttcccagatt gccgtcatac ccaagcaatc gtgaaagaga
    36421 ttggtgttga gtgtccaagc tgtcatcagg gacaaattat tgagcgaaaa accaagcgta
    36481 atcgcctatt ctatggttgc aatcgctatc cagaatgtga atttacctct tgggacaagc
    36541 ctgttggtcg tgactgtcca aaatgtggca acttcctcat ggagaaaaaa gtccgtggtg
    36601 gtggcaagca ggttgtttgt agcaaaggcg actacgagga agaaaagatt aaataagagg
    36661 aggggcccga aagtaaattt caggctcctt ttggttagaa cttgacaaaa tacatcattt
    36721 tatgcgaaac tagaagaaga ttattttata ctcaatgaga atcaaagagc aaattagaaa
    36781 gctagtcgca ggttgctcaa agcactactt tgaggttgaa gatggaagct gacctggttt
    36841 gaagagattt tcgaagagta ttaactagga gaagttatgc gtattatcta tctaattatt
    36901 ggttttttat cgctgacctt ggctattgtt ggggttgttt tacccttgtt gcctacaaca
    36961 cctttccttt tgttgtctat tgcttgtttc tccagaagtt ccaagcgatt cgaagattgg
    37021 ctttatcata ccaagctcta tcaagcatat gtagctgatt ttcgtgagac caagtctatt
    37081 gcgcgtgaac gaaagaaaaa aatcatcgtc tctatctacg tcttgatggg aatttctatt
    37141 tattttgcac ctcttttacc agtcaaaatc ggtctgggtg ctttgaccat ctttattact
    37201 tattatctct tcaaggtcat tccagacaaa gaatagttaa aacagtagtt atttgccttg
    37261 ataaaattga aagcatattc ataacaatat gatataataa aattgaagta atattcaagg
    37321 agaatcaaat gatttacgaa ttttgtgctg aaaatgtgac tttacttgaa aaagcgatgc
    37381 aggctggagc tcgtcggatt gaactctgtg ataatctagc agttggtggg acaacaccca
    37441 gctatggagt gactaaggca gcggttgaac tggcagctaa ctacgataca accatcatga
    37501 ccatgattcg gccacgtggt ggtgactttg tctataatga cctagaaatt gctatcatgc
    37561 tagaagacat tcgtttgact gctcaggctg gaagtcaagg ggttgtattt ggagctttaa
    37621 ctgctgataa aaagttggat aagcctaatc tggaaaagtt aattgctgca tcaaaaggaa
    37681 tggaaattgt ctttcacatg gcctttgatg aactaagtga tgaagatcaa ccggaagcta
    37741 ttgactggct cagtcaagcc ggtgtcactc gtatcctaac tcgtgctggt gtgtctggcg
    37801 actccttaga aaaacgtttt gttcactatc acagaatttt ggagtacgct aaaggtaaaa
    37861 ttgaaattct accaggtggg gggattgacc ttgaaaaccg tcaaaccttt atcgaccagg
    37921 tgggggtaac acaattgcat ggtactaagg ttgtttttta aaaaatagaa aggaactgct
    37981 agctttgggt agcagttttc acttatgttt gaaattttta aatcctatca atttaatcaa
    38041 gaaaaggctc atgattatgg ttttatagaa aatagcgaag tctggacata tagttgccag
    38101 attttgcaag gtgactttgt catgactgtg tccatcactg ctgataatgt gaactttcaa
    38161 gtctttgacc aagagactgg tgacctctat cctcacgttt atatggaaag catgagggga
    38221 agttttgtcg gaaatgtccg tgaggcttgt ctggagattc tttaccagat tcggaaggct
    38281 tgttttgatg tgcaagattt tatctgtcat cagactaagc gtatcatgac tcaagttcag
    38341 gaaaagtatg gaaaccagtt ggagtatctg tgggaaaaat cgcctgatac agctgtattg
    38401 cgccatgaag gcaatcaaaa gtggtatgcc gtcttgatga aaatctcttg gaataagctg
    38461 gaaaagggca gagaaggaca agtggaagca gtcaacctca agcatgacca agtagctaat
    38521 ttgctttcac aaaaggggat ttatccagcc ttccatatga gcaagcgcta ctggattagt
    38581 gtgtcccttg atgatacttt atcagatgaa gaagtactgg aattgataga aaaaagttgg
    38641 aacttaacct ctaaaaaatg aaatatttta ataattttca tgaactttca attagctaaa
    38701 tattctttac tgaagagatt tttagaaaat ataggattta ccacactaga ggaatatggt
    38761 gccatcttca aatacctgat tgagaatgtc aagacggatc gtcagatcat ctattcgcct
    38821 cactgtcatg atgacctcgg aatggcagtg gcaaatagcc ttgctgctgt caagaatggt
    38881 gcaggacgtg ttgaagggac tatcaatggt attagggagc gagctgaaaa tgctgctttg
    38941 gaagaaattg cagtggctct caatattcgc caagattact accaagtaga aaccagtatt
    39001 gtcctaaatg agaccatcaa tacgtcagaa atggtttctc gcttctctgg tattccagtt
    39061 cctaaaaaca aagccgtcgt tggtggcaat accttctccc acgaatctgg tattcaccaa
    39121 gatggagtcc ttaaaaatcc tctcacttat gagatcatca cacctgaatt ggttggtgtt
    39181 aagattctgc ttggaaaatt atctggtcgc catgcttttg ttgagaaact gagagaattg
    39241 gccctagatt ttacagaaga ggatatcaaa ccactctttg ctaagttcaa ggcactggtc
    39301 gataagaagc aagaaatcac agatgcagat attcgagctt tggtagctgg aaccatggtt
    39361 gaaaatccag aaggcttcca ctttgatgat ttacaacttc aaactcatgc agataatgac
    39421 attgaagcgc tcgttagcct agccaatatg gatggtgaga aagtcgaatt taatgcgaca
    39481 gggcaaggtt ccgttgaagc aatctttaat gctatcgata agttctttaa ccaatctgtt
    39541 cgtttggtgt cctacactat cgatgcggta acagatggaa tcgataccca ggatcgggtt
    39601 ttggtcactg ttgaaaacag agatacagaa accatcttta atgcagcagg gcttgatttt
    39661 gatgtgttga aggcttctgc tattgtctat ataaacgcta atacctttgt tcaaaaagag
    39721 aatgcaggtg agatgggacg cagtgtttct taccacgata tgcctagtgt gtaaaggaga
    39781 aggctatggc aaagaaaata gtagctctag caggagacgg aattggccca gaaatcatgg
    39841 aggttggttt agaagttctg gaggctctag ctgaaaaaac aggttttgac tatgagattg
    39901 acagacgacc gttcggaggt gcagatattg atgcagcatg acctccctta cctgatgaaa
    39961 cccttaaggc aagtagggaa gcagatgcta tcctactagt agctatcggt agtcctcagt
    40021 atgatggagc agtggttcgc cctgaacaag gcctgatggc tctccgtaag gaactcaatc
    40081 tttacgctaa tattcgtcct gtaaaaatct ttgacagtct caagcatttg tcactactca
    40141 aactggaacg aattgctggt gtagactttg tcgtggtgcg tgaattgaca ggcgggattt
    40201 actttggaga tcatattctt gaagagcgca atgcgcgtga tatcaacgac tatagctatg
    40261 aggaagtgga gcggattatt cgcaaagcct ttgaaattgc aagaaatcgc agaaaaatcg
    40321 ttactagtat cgataagcaa aatgttctag cgacctcaaa actctggcgg aaagtagctg
    40381 aggaagtcgc acaggatttc ccagatgtaa ccttggaaca tcagctggta gactcagctg
    40441 ctatgcttat gattaccaat cctgctaagt ttgatgttat tgtaacggag aatctttttg
    40501 gagatatttt atctgatgaa tcaagcgtct tatctggtac acttggggtt atgccatcag
    40561 ccagtcattc tgaaaatgga ccaagtctct atgaacctat tcacagttca gcacctgata
    40621 ttgcaggtca aggaattgcc aatcctattt ccatgatttt atcagtttcc atgatgttga
    40681 gagatagttt cggacgttat gaggatgcag agcgtatcaa acgtgctgtt gagacaagtc
    40741 tggcggcagg aattttaacg agagatatag gaggtcaggc ttcaacaaag gaaatgacgg
    40801 aagctattat tgcaaggtta tgaagttaga cgaaaaaatt actctagtcc ttttgatttg
    40861 gaatgtcatc attttcttga tttatggtat tgacaaatct aaggcaagga gaagagtttg
    40921 gcgcatccct gagaaaatct tacttatttt agcctttact tttggtggtt ttggtgcctg
    40981 gctagcagga atcatctttc accacaagac tcgaaaatgg tactttaaaa tagtttggtt
    41041 tcttgggatg gtgaccacac tagtagcctt atattttatt tggaggtaat ggatggcagg
    41101 gtcttcgagg gaatacgctg cttgggctct agcggactat ggttttaagg tcgtgattgc
    41161 aggatctttc ggtgacattc attacaataa tgaactcaat aatggcatgt tgccaatcgt
    41221 tcagcctaga gaggttagag agaaactagc ccagctaaaa ccaaccgacc aggtaactgt
    41281 ggacttggaa caacaaaaaa tcatctcacc agttgaagaa ttcaccttcg agatagatag
    41341 cgagtggaaa cataaactcc taaatagttt ggatgatatc ggtattacct tgcagtatga
    41401 agagttgatt gctgcttatg aaaaacaacg accagcctac tggcaggatt agaaaaaata
    41461 gaaaaggaga tatagtaaac tgaaataaga tgtaaacaaa tgaattggag cttaacatcc
    41521 atttccagca attttttaga aactacagtg gactattctg gattcaacac attataaaat
    41581 tatgacaaaa cacattcaca agaaggctac gacattttaa aaggtgaggg cggatgtatc
    41641 gtttgcccta ctaaagttgg ttacattatc atgaccagtg acaaggcagg acttgagcgt
    41701 aagttcgcag ccaaagaacg taagcgtaac aaaccaggtg ttgttctctg cggtagcatg
    41761 gatgaacttt gcgctttagc gcaactcaac ccagaaattg aagcattcta ctaaaaacat
    41821 tgggatgaag atattcttct tggttgtatc cttccttgga aaccagaagc ctttgaaaaa
    41881 ctcaaagcat acggggatgg ccgtgaagaa cttatgactg atgtacgtgg tactagctgt
    41941 tttgttatca agtttggaaa agcaggtgaa caattggctg ccaagctttg ggaagaaggt
    42001 aaaatggtct acgcctcatc tgcttcaatg acaaaacgat tgaaactcgc tatgagcaag
    42061 gtgtaatggt gtctatggtc gataaggacg gcaaactcat cccagaacaa ggaggagcac
    42121 gttcaacttc accagctcca gttgtgatcc gtaaagggct tgacattgat atagtaaaat
    42181 gaagtaagag caggacaaat taatcaggac agtcaaatcg atttctaaca atgttttaga
    42241 agtagaggtg tactattcta gtttcaatcc actataaaat catgatgcac ctgtcagata
    42301 cttttaactc atgggactac cgtcaggttg agtattatta ggatagagaa gaagtctagt
    42361 gttaaggaca ttacagctca taatactagg cttttttata gaaattcttt tctttttcta
    42421 taggatatgg tattctatgt agaaaatata tgttaataag taatgccaat atttaaacat
    42481 cattagtaaa aggagttaga ttgatgaata aaagaaaagt tagtttagaa gatttttata
    42541 aatggtatag tctaaataaa gaagagttat taaataaggc aactgttggt gaaaagttta
    42601 atgataaatt aaaagaagag tttctccagg aatggccttt ggataggatt ttaacaatgt
    42661 caatcgatga atatgtaata ggaaagggac agcaaaataa gtctttatgc tacgctcttg
    42721 agaagggaaa atacaaaaat ctatttcttg gaatttctgg tggctcagct tcaaaatttg
    42781 gtatttattg gaataaaaaa acaaacaaat ataaagatca agctaataat gagatttcag
    42841 agttggatca gcgattttca aaattaaaat cagatttgta tgaaattatc aaagaaggta
    42901 ttcgttttaa ctttgaaaat cctatttttg atatgaaaag atcaacaaat gaatttattg
    42961 gtcgttctgc tatggtgaca aaattacttt gtatctatac tgagggagat cctttctttg
    43021 gtgtaaatat taatagtcag aaagaatttt ggaaccactt tgtttctcag acaaatcaag
    43081 gtggacctta tctgcaaaat cataaaataa ttgaactgat gtccaaaact tatcctgagt
    43141 tggagccatc gaaattagga actatgcttt ttgagtattc taagcttttt atggaaaata
    43201 aggaagacaa tagtacaatg gattcatcaa acaattttcg tcatcaatta actcaatctc
    43261 tattaaagtc tccaaacctt atccttcgtg gtgctcctgg cacaggaaag acttatcttg
    43321 ctaaagaaat tgccaaagaa ttaacggatg gcaacgaaga tcaaatcgga tttgtacaat
    43381 ttcacccatc atatgattat acggattttg tagaaggttt aagaccagta tcaaatgggg
    43441 atggagctat tgagtttagg ctacaggacg gtatttttaa agatttttgt cagaaagcaa
    43501 aagaaaccca attgattgga ggacaagata attttgatga ggcttgggat tcttacttag
    43561 aatatataaa tgttgctgaa gaaaaagaat atataacaaa aacatcttac ttatctgtta
    43621 atagtagaca aaatttgtca gtaaattatg atagtggtgt tccaggatgg tcactaccta
    43681 gcaaatatgt ttacgagttg tataaagata aaaattataa taagcaagaa tactacaaaa
    43741 gtggtggaaa aactgtccta gaaacattga gaaagagatt tggtttgaaa gactatgttt
    43801 ccccaacaga aattgatact gataagaaat tcgttttcat catcgatgaa atcaatcgtg
    43861 gggagatttc taagattttt ggcgaactct ttttctctat cgaccctggc tatcgtggtg
    43921 aaaaaggaag tgtttctacc caatatgcaa atctacacga aactgatgaa aagttctata
    43981 tccccgaaaa tgtttacatc atcggaacta tgaatgatat tgatcgttca gtggatacct
    44041 ttgattttgc tatgcgtcgt cgttttcgtt ttgttgaagt tactgccgag ggtcaagttg
    44101 gcatgttgga taaagagctg aatatccatg cagaagaagc aaaaattcgt ctaagaaact
    44161 tgaacgctgc tatcgaaaat gttcaggaat taaacagtca ttatcatatt ggaccaagtt
    44221 attttcttaa gttgaaggat gtagattttg actatgaatt actctggtcc gattatatta
    44281 agcctctcct agaagactac ttgcgaggtt cttatgatga ggttgaaact ttggaaactt
    44341 tgaaaaaagc atttgaactg acaaataatg agcaaaaaga tcaggcagta gctgatgaca
    44401 atgaaagcga tgaaaacgat gatgcggatt actgataatc aacacaagat tattaaagaa
    44461 aaatttgttg aagaatatcc taaactaagc aatcttcttt tagacagaac cttggaaagt
    44521 ctatcccaag atgaacgtat tttcattttt ccaaatgatt tgactcatac tccagatttg
    44581 gataaaaaac aaaagatttt ggaaacgatc aatcaggaaa tcaagacagg aaatgtgatt
    44641 ggttttcttg gatatggtca ggaaagatta acgatttcct cacgattttc tgatgagagt
    44701 aatgaccatt ttttgcatta tctcttaaac aaggttcttc atatcaatct cactagttta
    44761 gatgttgctt tgtctcgtga agagaggctt tatcaacttt tgatgtatct cttccccaag
    44821 tatctacaag ctgctattcg aaaaggtctt tataaggaat atcatcgatt ttctcataac
    44881 gacagtcatg ttaagggagt gattgatgta agaaaccatc tcaagaaaaa tcttcctttc
    44941 acgggaaata ttgcctacac aacgagagag ttcacctatg ataatcccct catgcagttg
    45001 gtccgtcaca ctattgaata cattaagaat cagaaaagca ttggtcaagg ggtactagat
    45061 aatctctcaa ctagtcgtga aaacgtatct gaaatcgtgc gtgtaacgcc ctcttataaa
    45121 ctagctgatc gtgctaagat tattcgggga aatcaatcta aacctatacg tcatgcatac
    45181 tttcacgagt acagaaactt acaagaactt tgtctgatga tcctaaacca agaaaagcac
    45241 ggtttagggt atcaagatca aaaaatctat ggtattctct ttgatgttgc ctggctttgg
    45301 gaagagtatg tttacacctt gttgccaaaa ggttttgtac atcccagaaa taaggataag
    45361 acggatggaa tttcagtatt ttctgttggg aaacgaaaag tatatccaga tttttatgac
    45421 agagaacgaa agattgttct agatgcaaaa tataaaaaac tggaattgac tgaaaaagga
    45481 atcaatcgtg aggacttatt ccagctgatt tcctattctt atattttaaa agctgagaag
    45541 gctggacttg tttttccgag caaggacaag gttattgata atgagatggg aaacctagca
    45601 ggttatggag ctttgttgaa gaaatggtct atccaaattc ctcagaagtc ttcatcttat
    45661 agtgcatttt gtaaaatgat ggaaaattca gattatagtg cattttgtaa aatgatggaa
    45721 aattcagaag aaaattttaa agcgattatt gatgaagaag tggggagaaa ataatttccc
    45781 ctctttcttt tatttttaac acaagtaaaa cccgaacaat atatttcaat tcataaaata
    45841 atttgacaaa aactgtactt tggtttataa taaattaagg aaacgtcgga aaagacgtag
    45901 tgatgcgaga gcataggtag gtcattacaa aagaaacgag acatcgatat gttaaatgaa
    45961 tttccaattt ttgattacga agatattcaa ttgattccaa ataaatgtgt cattaaaagc
    46021 cgtgcagaag cggatacaag tgtcacttta ggaaatcaca cctttaaact acctgttgtg
    46081 ccagcgaata tgcagacgat tttggatgaa aatgtagcag agcaactggc taaaggtggt
    46141 tacttctaca ttatgcaccg ttttgatgag gcaggacgca ttccttttat taaacaaatg
    46201 cacgatcaag ggctcattgc ttccatctct gtcggtgtta aggactatga gtatgatttt
    46261 gttagccagc tcaagactga tgctcctgag tatatcacta ttgatattgc tcatggtcat
    46321 gcggatagcg tgatttctat gattcaacat atcaagaaag aattgccaga tacctttgtc
    46381 attgctggaa atgtgggaac accagaagct gtgcgtgaat tggaaaatgc tggtgcggat
    46441 gctactaagg tcggaatcgg tcccggtaag gtttgtatca ccaaggttaa gactggtttt
    46501 ggtacaggtg gttggcagtt ggctgctcta cgctggtgtg ccaaggctgc gcgtaaaccg
    46561 attatcgctg atggaggaat tcgtactcac ggtgatattg ctaagtctat ccgcttcggt
    46621 gctagcatga tcatgattgg ttccctcttt gcaggacaca ttgaaagtcc agggaaaacg
    46681 attgaagtcg atggtgaaca gttcaaagaa tattatggtt cagcctcaca atatcaaaaa
    46741 ggtgcttaca aaaatgtgga aggcaaacgt atcttgcttc ctgctaaagg tcatctgcaa
    46801 gacactttaa ctgagatgga acaagacctt caaagtgcta tttcttatgc aggtggacgt
    46861 caggttgctg accttaaaca cgttgattat gtgatcgtga aaaactccat ctggaatggg
    46921 gatgcttccc actaagacgg ggtctttgac caaaaaactt gttattagag caaatttctg
    46981 ttataataaa acaagtttcc acccttagtg taatggatat cacgtaagat tccggttctt
    47041 gagatggggg ttcgattccc tcagggtgga tgtaaacatc ctaaaaagcc tttaataggg
    47101 cttttttctt tatcctgacc caaatttgcc gctaaaactg agaatctctg tctaaagaat
    47161 tcccaaatgc tttccagtcc cgttttagag tgactcaggg ggcttttttt gatataataa
    47221 aaaggactgt tatcagttag aaagaggttg gtatgaaaga attacaaact gtactaaaga
    47281 atcattttgc aatcgaattt gcagacaaaa atttactgga aactgccttt actcatacga
    47341 gttatgccaa tgagcaccgc ctcttaaaaa tttcacacaa tgaacgcttg gaatttttag
    47401 gagacgctgt tctacagtta ttgatttcag aatatctata taaaaaatat cctaaaaagc
    47461 ctgaaggtga cctatcaaaa ctccgtgcta tgattgtccg tgaggagagt ttagctggtt
    47521 ttgcgcgtga ttgccagttt gaccagttta tcaagttggg taaaggggaa gaaaaatcag
    47581 gtggtcgcaa tcgtgacacc attcttggtg atgcctttga agcctttctt ggtgcccttc
    47641 ttttggataa ggatgtggcc aaggtcaagg aatttatcta tcaagtcatg attcctaagg
    47701 ttgaagcagg cgaatttgag atgattacag actataaaac ccatctccaa gagttacttc
    47761 aggtcaatgg tgatgtggct attcgttatc aggtgatttc tgaaacaggg cctgctcacg
    47821 ataaggtctt tgatgtagaa gttcttgttg aaggtaagag catcggtcaa ggccaaggtc
    47881 gttctaagaa attagcagag caggaagctg ccaaaaatgc cgttgagaag gggctggatt
    47941 catgtattta aaggaaatcg aaattcaggg gttcaagtct tttgctgata agaccaaggt
    48001 cgtttttgac caaggtgtga cggcagttgt tggacccaat ggatctggaa agtccaatat
    48061 tacagaaagt ctgcgttggg ctttggggga gtctagtgtc aagagtctcc gtgggggcaa
    48121 gatgccggat gtcatctttg ctggaacaga aagtcgcaaa ccgctcaatt atgcttctgt
    48181 agttgtgact ctggataatc atgacggatt tatcaaggat gcaggtcaag aaatcagggt
    48241 ggaacgccat atctatcgta gtggagatag cgaatacaag attgacggca agaaagtccg
    48301 tctgcgtgat attcatgacc ttttcttgga tacaggtttg ggacgagatt ccttctctat
    48361 tatttcccaa gggaaggttg aggagatttt taattccaag tctgaggaac gacgagctat
    48421 ttttgaagaa gctgctggag ttttaaaata caagactcgc agaaaagaaa ccgagagtaa
    48481 actgcagcaa actcaggata atctggaccg cttagaggac attatctacg agttggataa
    48541 tcaaatcaag cctcttgaga agcaagctga gaatgcccgt aaatttctag acttagaagg
    48601 tcaacgcaag gctatttact tggatgtatt ggttgctcaa atcaaggaaa ataaggcaga
    48661 actagagtcg acagaagaag agttggctca ggttcaagaa ctcttgatga gttattacca
    48721 aaagcgtgaa aaattagaag aagaaaatca aactcttaaa aagcaacgcc aagatttaca
    48781 ggctgaaatg gccaaagacc aaggcagttt gatggacttg actagtctga ttagtgattt
    48841 agaaagaaaa ttagccctat cgaaactgga gtctgagcaa gtggccttga atcaacagga
    48901 ggcacaagct cgtttggctg ctttggagga taagagaaat tcactcagca aagaaaagtc
    48961 tgataaagaa agctctttag ctctgttaga gggaaatcta gtccaaaata atcaaaaact
    49021 caatcgttta gaagctgaat tgctggcttt ctcagacgat cctgatcaga tgattgagct
    49081 cttacgtgaa cgctttgtag ctcttttaca agaagaagcg gatgtctcaa accagttgac
    49141 ccgtattgag aatgagttgg aaaatagtcg tcagctttct caaaaacaag cagatcaact
    49201 agaaaagctg aaagagcaat tagctatagc taaagagaag gctagtcagc aaaaggaaga
    49261 gcttgaaact gccaaggagc aggttcagaa attattggct gactaccaag ctattgccaa
    49321 ggagcaagag gagcagaaaa cttcctatca agctcaacaa agccaactct ttgaccgtct
    49381 ggataatctc aaaaacaagc aggccagagc tcaaagtttg gaaaatatcc tgagaaatca
    49441 tagtaacttt tatgcaggtg ttaagagtgt tctccaagaa aaagatcgcc taggtgggat
    49501 tattggtgca gtcagtgagc atctgacctt tgatatgcat tatcaaactg ccctagaaat
    49561 tgcgcttgga gcgagtagcc aacatatcat cgtagaagat gaagagtcgg caaccaaggc
    49621 tattgacttc cttaaacgga acagagccgg tcgtgcaacc tttcttcctt tgaccactat
    49681 caaggcgcgt acgatttcta gtcagaacca agatgctatc actgtaagcc caggtttcct
    49741 tgggatggca gatgagttgg tgacttttga tactagactg gaagccattt tcaagaactt
    49801 gctagctacg acggctatct ttgatgccgt agaacatgcg cgtgcagcag ctcgccaagt
    49861 tcgttatcag gttcgtatgg tgacattgga tgggacagaa ttacgcacgg gtggttccta
    49921 tgcgggtggt gccaatcgcc aaaataacag tattttcatc aagccagaac tggagcaatt
    49981 acaaaaagaa attgctgcag atgaagcaag cttgcgttca gaagaagcgg ctttgaagac
    50041 cttacaagac cagatggcta cattgacaga aagattagaa gtcatcaaat ctcaaggaga
    50101 acaggcacgt attcaggagc aaggcttgtc cctcgcttat cagcaaacta gtcagcaagt
    50161 tgaagaactg gaaactcttt ggaaactcca agaagaggaa atagatcgtc tttccgaggg
    50221 agattggcaa gcggataagg aaaaatgcca agatcgtctt gctgcaatcg ccagtgacaa
    50281 gcaaaatctg gaagctgaga ttgaagagat taagtctaac aaaaatgcca tccaagaacg
    50341 ctatcaaaac ttgcaggaag agctagcgca agctcgtttg cttaagacag aactgcaagg
    50401 gcaaaaacgt tatgaagttg ctgatattga acgcttaggc aaggaattgg acaatcttga
    50461 ttttgaacaa gaggaaatcc agcgccttct tcaagaaaag gttgataatc ttgagaaggt
    50521 tgatacagaa ttgctcagtc aacaggcgga agaagccaaa actcagaaaa caaatctcca
    50581 acaaggtttg attcgcaagc agtttgagtt ggatgatatt gaaggtcaac tggatgatat
    50641 tgctagtcat ttggatcagg ctcgccaaca gaatgaagag tggattcgca agcaaacacg
    50701 tgctgaagcc aagaaagaaa aggtcagcga gcgcttgcgc tatttacaaa gtcaattaac
    50761 agaccaatat cagattagct atactgaagc tctagaaaag gcgcatgaat tggaaaacct
    50821 caatctggca gagcaagagg tgcaggattt agagaaagct attcgctcac tggggcctgt
    50881 caatatagaa gctattgacc agtacgaaga agttcacaat cgtctggatt tcctaaatag
    50941 ccaacgagat gatattttgt cagcgaaaaa tctgctcctt gagaccatta cagagatgaa
    51001 tgatgaggtc aaagatcgct ttaaatcaac ctttgaggcc attcgtgaat cctttaaagt
    51061 gaccttcaaa cagatgtttg gaggaggtca ggcagactta atcttgactg agggagactt
    51121 gttgacagct ggggttgaga tttctgttca acctccaggt aagaaaatcc agtcgcttaa
    51181 cctcatgagt ggtggtgaaa aagccttatc agctcttgct ttgctttttt ctatcattcg
    51241 agttaagact atcccatttg tcatcttgga tgaggtagag gccgcgctgg acgaagccaa
    51301 tgttaaacgt tttggggatt acctcaatcg atttgacaag gacagccagt ttatcgtcgt
    51361 aacccaccgt aagggaacca tggcagcggc tgattctatc tatggagtga ccatgcaaga
    51421 atcgggggtc tcaaaaattg tttcggttaa gttaaaagat ttagaaagta ttgaaggatg
    51481 acaattaaac tagtagcaac ggatatggac ggaaccttcc tagatgggaa tggacgcttt
    51541 gatatggatc gtctcaagtc tctcttggct tcctacaagg aaaaagggat ttactttgcg
    51601 gtggcttcgg gtcggggatt tctgtctctg gaaaaattat ttgctggtgt tcgtgatgac
    51661 attattttca tcgcggaaaa tggcagtttg gtagagtatc aaggtcagga cttgtatgaa
    51721 gcgactatgt ctcgtgactt ttatctggca acttttgaaa agctgaaaac gtcaccttat
    51781 gtagatatca ataaactgct cttgacgggt aagaagggtt catatgttct agatacggtt
    51841 gatgagacct atttgaaagt gagtcagcat tataatgaaa atatccaaaa agtagcgagt
    51901 ttggaagata tcacagatga cattttcaaa tttacaacca acttcacaga agaaacgctg
    51961 gaagctggag aaacttgggt aaacgataat gtccctggtg tcaaggctat gacaactggc
    52021 tttgaatcta ttgatattgt tctggactat gtcgataagg gagtggctat tgttgaatta
    52081 gctaaaaaac ttggtatcac aatggatcag gtcatggctt ttggagacaa tcttaatgac
    52141 ttacatatga tgcaggttgt gggacatcct gtagctcctg aaaatgcacg acctgaaatt
    52201 ttagaattag caaagactgt gattggtcac cataaggacc agtcggttat agcttatatg
    52261 gagggcttat aatggcagat ataaaattaa tcgcattgga cttggatggt accttgctga
    52321 ctactgataa aaggctgacg gatcgcacca aggcaacttt gaaagctgcg agtgatcgtg
    52381 gtatcaaggt cgtattgaca actggtcgtc ccttaaaagc catggacttc tttctccatg
    52441 agttagggac tgacggccat gaagatgagt ataccattac ttttaatggt ggattagttc
    52501 agaaaaatac aggagaaatc cttgataaaa cagtcttttc atatgatgat gtggcacgtt
    52561 tgtatgagga aacagagaaa ttatcactgc ctcttgatgc catctcagaa ggaacagttt
    52621 atcaaatcca atcggaccaa gaaagtcttt atgccaaatt caatccagct ttgacttttg
    52681 ttccagttga ctttgaagac ctgtctagtc aaatgaccta caacaaatgc gtgactgcct
    52741 ttgctcaaga acccttggat gcagccattc agaagatttc tccagaattg tttgaccaat
    52801 atgaaatctt taaatcacgt gaaatgttgc tagaatggtc accaaagaat gttcataaag
    52861 caacaggttt ggcaaaacta attagccatc ttggaattga tcaaagtcaa gtgatggcct
    52921 gtggtgacga ggccaatgac ctctctatga ttgaatgggc agggctcggt gttgccatgc
    52981 aaaacgctgt tcctgaagta aaggcagccg caaatgtagt gacgccgatg accaacgatg
    53041 aggaagctgt cgcctgggct atcgaagaat atgtgctaaa ggagaactaa gatatgggat
    53101 tatttgaccg tctattcgga aaaaaagaag aacctaaaat cgaagaagtt gtaaaagaag
    53161 ctctggaaaa tcttgatttg tctgaagatg ttgatcctac cttcacagaa gttgaagaag
    53221 tttctcaaga agaagctgtg cttgaagaaa gtcaggattc agagccagct gtaggggttt
    53281 ctcaagaaga aatagaagaa ttaccagagg aagagaagct tgagcacgaa ggaactatag
    53341 aagaaaataa ttctgaagtt cttgaagcag aaaggcctca aacagaagaa actgttcagg
    53401 aaaaatatga ccgcagtctt aagaaaactc gcacaggttt cggtgcccgc ttgaatgcct
    53461 tctttgctaa cttccgctct gttgacgaag aatttttcga ggaactggaa gaactgttga
    53521 ttatgagtga tgttggtgtc caagtcgctt ctaacttaac ggaggaacta cgttacgaag
    53581 ccaagcttga aaatgccaag aaacctgatg cacttcgtcg tgtcatcatt gagaaattgg
    53641 ttgagcttta tgaaaaggat ggtagctacg atgaaagcat ccacttccaa gataacttga
    53701 cagttatgct ctttgttggt gtgaatggtg ttgggaaaac aacttctatc ggaaaactag
    53761 cccaccgcta caaacgagct ggtaagaagg tcatgctggt tgcagcagat accttccgtg
    53821 cgggtgcagt agctcagcta gctgaatggg gccgacgagt agatgttcca gtagtaactg
    53881 gacctgaaaa agctgatcca gccagcgtgg tctttgatgg tatggaacgt gccgtggctg
    53941 aaggtatcga tattctcatg attgatactg ctggtcgtct gcaaaataag gataacctta
    54001 tgactgagtt ggaaaagatt ggtcgtatta tcaaacgtgt tgtgccagaa gcaccacatg
    54061 aaaccttctt ggcacttgat gcatcaacag gtcaaaatgc cctagtacag gccaaagaat
    54121 tttcgaaaat cacaccttta acgggaattg ttttgactaa gattgatgga actgctcgag
    54181 gaggtgtggt tctagccatt cgtgaagaac tcaatattcc tgtaaaattg attggttttg
    54241 gtgaaaaaat cgatgatatt ggagagttta actcagaaaa cttcatgaaa ggtctcttgg
    54301 aaggtttaat ctaatcagaa gcaaaaatcc tgcaaggcat aaacttgcag gaaatttttt
    54361 tattcgaaac gaccatcttg acgataggcg atatctggtt gccaagtcca tttggcaccg
    54421 aatttttcaa gtaggtcaaa gctggcttga ggtcccatgc ttccagcttt atagtcatga
    54481 agtggggcac cattttcagc ccagagctct tcaatacggt caatcaactt ccatgatgca
    54541 ccaacttcat cccagtggct aaagttagtt gagttgttat ttaggacatc ataaatcaat
    54601 ttctcgtatg gttctggaga agcaccagtt gcagtcgcat ctgtacggta atcaagtgag
    54661 ttaggagcca agttaaattc ttctcctact tgcttcccat ttaggctaag agagaagcct
    54721 tctgttggtt gaatatagat ggtcaaaata tttggagcaa gtggttctcc aaagatagaa
    54781 tccatttgtt taaagacgat gttgacatga gttccttttt cagtcagtcg tttacctgta
    54841 cggaaaaaga aaggaacact acggaatcga tcgctgtcta caaagaaggc accagatgta
    54901 aaggtttcag ttgttgattc tggattcaca tttggctcgc tacgataaga gatgtatttc
    54961 atgccatcaa tcttaccaga gcggtattgc ccacggataa agtgttcttt gagttcttca
    55021 tcagttggat gatagaggtt tttaaagacc ttaatctttt cagcacgaat ctcgtctttt
    55081 gtgaagattg ctggtttgtc catggcgagg agcgaaagaa gttgtagagt gtggttttgg
    55141 accatgtcac ggagggcacc ggattggtca tagtagccac cacgttcttc tacacccaag
    55201 cgctccgcaa aggtaatttg aacattgtcg ataaaatcct tgttccaaac gttttcaaaa
    55261 atcaagtttg caaagcgaac tgcaaagatg ctttggatca tttccttacc aagataatgg
    55321 tcgatacgga aaatttgttc ttcgtcaaat gttgctagga gttcgtcatt caacttgctt
    55381 gcagttgcgt aatctgtacc aaatggtttt tcaacgatca agcgctcaaa acctttgcca
    55441 tcgacaatgt tttcagattt gaggtgtttg gcaatggttc caaagaactg aggtgccata
    55501 gacaagaaga agagcttatt gtgttcagct tggtattttt cattaagctc agcttgtaat
    55561 tgacgcaaag caatataatg ttccgaatca ttgacatcat ggctttgata gtagaagtgg
    55621 ctagcaaatt cttgggcttg ctcggtacta tctgccaaat caaggatgga ctcgacaact
    55681 acagattcaa aatattcctt actccaaggt ctacgggcag ttccaataac ggcaaagtgc
    55741 ttggaaagat tgccggattg atatagtcta aaaagggaag ggtagagctt gcgtttagcc
    55801 aggtctccac tcgcaccgaa aattgtaaca ataaccttag atgacatcta gctacctaat
    55861 ttctattttt attcctagtc ttgctaggta tgaggaaacc tcatttcata aacttaattc
    55921 taacataatt ttccgaaaaa tcaaaaattc caatacgagg tagaaaaact gcaaggaaat
    55981 ccttacagtt tgagtttaga cgtttaagac cttatctaag aactctttca gacgagggtg
    56041 ttgtgggtta tcaaagattt ggtcaggtgt tccgtcttca aggaactcgc catctgcagt
    56101 aaagataacg cggttggcaa cctgacgagc aaatcccatc tcatgggtta cgataatcat
    56161 ggtcatgcct tgctcagcca attccttcat aacgttaagt acgtctccaa ccatctcagg
    56221 gtcaagggca gaagttggtt catcgaagag catgatgtct ggattcattg ctaggccacg
    56281 agcgatggcc acacgttgtt tttgaccacc tgataggtta tctggattgg cattagcttt
    56341 atctgctagt ccaacctttt caagcaactc cattcccaat tcctcagctt cttccttagt
    56401 catcaacttg tgctcaatag gagcaaaggt gatgttgtcc aatacagaca tatgagggaa
    56461 gaggttgaag tgttggaata ccatgccgat attttcacgg acgtggtcaa cattggttgt
    56521 tttttcagtt aaatcatagc cgttcacagt gatgtgaccg ctagtgactt cttctaaaag
    56581 attgaggcta cggaggaaag ttgacttacc agaacctgaa ggaccgatga tacaaacaac
    56641 atctccttca tagaacttag tcgtaattcc ttttaggact tcattttttc catagtgctt
    56701 gtgtaaatca tttacatcaa tttttaattt tgccattaac gaatcctctt ttctaagcgt
    56761 ttcgctagtc tagtcaaaag tgtgataatt acaagataga agatagcaag gattgcatac
    56821 atcttgaaac tttggtagtt acgagcaatg ataatcttac cagtttggaa gagttcaacc
    56881 aaaccgatag cagatacgat agttgtatct ttaagagcga taacgaattg gttgacaaag
    56941 tttggcaaca tcaatttagt tgcttgtggc aagataatct tacgcatggt ttttccataa
    57001 gagataccca agcttcggct ggcttccatt tggccaactg gaacggcctg aataccacca
    57061 cgaacgattt cagcgatata agcagccgca ttgagtgaga gggcaatggt tccagctaca
    57121 aagtcgttaa ttgggctttg ttggcctgtg atagactcga tgaagtttgg aattccccag
    57181 aagatgaagg ctgcaagaat catcaatgga ataccacgaa taacgtcaac gaaaatctca
    57241 gagatgacgc gaagagattt gtatgggcta acgctaaaca taccgaagat aattccgatg
    57301 acaatggcaa tagcaaatga gataagagct agagcaagag tgataccaag accgctaagg
    57361 agttgtttgt agttgttttg aagcaagccc cagagcgttg tttcgtcaac agtacttgtt
    57421 gaagcagttg aagattcgct agctaggtat ttgtcaagaa tcttttggaa ttcaccgttt
    57481 gctttaaggt ttgcaagtcc gttgttgaac atttcaatca gttctggatt tgctcctttt
    57541 ttaacggcaa aggctgtttc accgattgga gttccagaga ttggagtttt caatttttga
    57601 ccttggctga tagaatattt gagaacaggt tcatcatcca taacggcatc aatggcacca
    57661 gtgtttaaac tgtcatacat tgaagaacca tcagcaaagg ttttgatttt gtaaccgtat
    57721 ttgctttgat tttctgttag gaaggtttga gaagcagttc cgtttttaac accgactgtc
    57781 tttcctttta gatcttcata agaagcaata ttgcttgatt ctttgacacc aagaatggta
    57841 ttagcagtgt agtatgattc tgagaagtca aaagttgcct tacgagcatc tgtgacagac
    57901 ataccagcaa tgataccatc ggcttgacca gcttggacag cactgatagc agcatcaaaa
    57961 ccagggttgg tgatttcaat ttcaaaacct tggtctttag cgattgcctt aatcaattcc
    58021 atatcaatac cagtgtattg gttgcttgaa ttttggaaaa caaaaggtgc aaaagaagaa
    58081 tcgctggcaa tgatatattt agccttaaca ggaatagctt ttaatcctgc gagagtagtt
    58141 gtagttggca ctgctgaaga tgatgaagca gtccatttct tgataatttt atcaagacta
    58201 ccatcttttt tcatttcagc caaggcttgg ttaaattcag taaccaggtg ctcgtattta
    58261 cttccttttt tcacaccgaa agcaaaactt cctacagctt caccatccat ttcaatatgg
    58321 aggtcttgac cttggttaat ggcatattcg ataacaggtt tgtcatccat catggcatcg
    58381 atggcaccag cactcaagct gttgttcatt aaatcaccag tgtcaaatgt tttaatagta
    58441 aagccgtatt tatctttgat tgtttcaagg aaacgttgag cggcagttcc gtttttaaca
    58501 ccaacggttt tgccagttaa ttggtcgtac ttgctaattt tgtgtgactt tgtagtagca
    58561 atgacaactt ttgtatcata gtaagtatca gacatggtga agactttttc acgttcttta
    58621 gtctttgtca tccctgccat gatagcgtcg gcttgcccag cttgaaccgc attgactgct
    58681 gcgtcaaatc caggatagga catctgaatg ttccagcctt taatctcagc gactttgtta
    58741 ataatgtcaa catcaattcc tttataagtt tgatctgaat ctttaaactc aaaaggtgca
    58801 taggcggtat cagaaacaat cttaatcgtt tctgctttgg caatacctaa tgagaaaatt
    58861 gggaataaaa ttagcaaaaa tgctagaaat tttttcttca tttttagtct ccttttccga
    58921 atattctctc attatatcag aaaaagtaaa aaaaggcaaa tttttatatt tttcgtgtca
    58981 gaaaatataa cattgatttt tccttttctt tcttgaattg ctattaaaaa ttgctataat
    59041 aatactatat atagaagaaa agaggacggg gatatgaaga acaaaagaat atttaaagac
    59101 ttccaagctt caaaaatgaa tttaaacctt tacacaagcc ccttgttagc ctttgttttt
    59161 gtcttcatag gagagtttgt ggcttatact ttatatggta ttagtttgtt agctctcatc
    59221 ggacttgcta gaaattttgg agaggctggt caaaatcttg caagctactt gcagaccttg
    59281 catcagagct tgacggataa aacaagtgac tttcgtttaa ttttaggatt actggccttt
    59341 ggttttattc ttaacactgt gttcagatgg acaagaaaag ttgagaaaag acctattcga
    59401 accttgggat tttatagaga gaattgcctc agcaatcttc tgaaaggatt tagtctaggc
    59461 ctggcacttt ttcttctgac cttgttaagt ttagtggtct taggtcaata tcgtttggaa
    59521 tccattcact tgaatcctta ttatcttgcc tttgtcgtct ttactatccc attttggatt
    59581 ttacagggga cagcagaaga agtggtggcc cgtgcttggc tacttcctca attggcctca
    59641 agaaccaatc taaaactagc tattcttata tctagcctgt tctttaccct gcttcatatg
    59701 ggcaattctg gcctcacccc tctatctcta gtaaatctct ttttattcgg agttgccatg
    59761 gctctttacc ttctcaaaac tgatacagtt tggggtgttg caggtattca tggtgcttgg
    59821 aattttgctc agggtaatct ctttgggatt ttagttagtg gtcaaccgtc aggaacgtct
    59881 ctgatgacct ttttaccaca aggcaatcaa gattggctat caggtggttc ttttggcata
    59941 gaaggttcca ttatgacaag tctggtatta ctactgctga ttgtctatct tgctaataaa
    60001 ttaaagaaag aaaatgaaag gatgtgactt cggtccgtcc ttttcttcgt gaaaatacta
    60061 taagtatgct aaaataggaa tagcacatgg agagaggatt cttatgatca atcacattac
    60121 agataatcaa tttaaactag tatcaaaata tcaaccatca ggagatcaac cccaagctat
    60181 cgagcagttg gtggataaca ttgagggggg agaaaaagct cagattctga tgggggcgac
    60241 tggaacaggg aagacctata ctatgagtca ggtcatttct aaagtcaata aaccaactct
    60301 ggttattgcc cacaataaaa ctctggctgg tcagctctat ggggagttta aggaattttt
    60361 ccctgaaaat gcagttgagt atttcgtatc ctactatgat tattaccagc cagaggccta
    60421 tgtcccttct agcgatacct atattgagaa ggatagttct gtcaatgacg agattgacaa
    60481 gcttcgccac tcagctacct cagccctttt ggagcgtaat gatgttattg tcgtggcctc
    60541 agtctcttgt atctatggtt tgggttcgcc caaggaatac gctgatagtg tcgttagtct
    60601 ccgtcctggt ctagagattt ctcgtgataa actcttgaat gacttggtcg atattcagtt
    60661 tgaacgcaat gatattgatt tccaacgcgg aagatttcgc gttcgtgggg atgtggtaga
    60721 gattttccca gcttcccgag atgaacatgc ctttcgagta gaattttttg gagacgaaat
    60781 tgaccgtatt cgtgaagttg aggctctgac aggtcaggtg ttgggagaag tggatcattt
    60841 agcgattttc ccagcgacac actttgtgac caatgacgac cacatggaag ttgccattgc
    60901 aaagattcag gccgagttgg aagaacaatt agctgtcttt gaaaaggaag gtaaactgct
    60961 tgaagcccag cgtttgaaac agcggacaga gtatgatatc gaaatgttgc gtgagatggg
    61021 ctataccaat ggggttgaaa attattctcg ccacatggat ggacggagcg aaggagagcc
    61081 tccttatacg cttctcgact tcttcccaga tgatttcttg attatgattg acgagagtca
    61141 tatgaccata gggcaaatca agggcatgta caatggagac cgttcgcgta aagaaatgct
    61201 ggttaattat ggtttccgtt tgccgtctgc tttggacaat cgtcctctcc gtcgggagga
    61261 gtttgagagt cacgttcatc agattgttta cgtttcagcg acacctggtg actatgaaaa
    61321 tgaacagacc gagacagtga ttgagcaaat cattcgtcca acgggactct tggatccaga
    61381 ggtggaagtc cgtccgacta tgggacagat tgatgacctc ttgggtgaaa tcaatgcccg
    61441 cgttgaaaaa aatgagcgta cctttatcac aactttgacc aagaaaatgg cagaggactt
    61501 gaccgactac ttcaaggaaa tgggtatcaa ggttaagtac atgcactcgg atatcaagac
    61561 cttggaacgg acggagatta tccgtgacct gcgcttgggt gtctttgatg tcttggtcgg
    61621 aattaacctg ctccgtgaag gaattgacgt tcctgaagtg agcctcgtag ctattctcga
    61681 tgctgacaag gaaggtttcc ttcgcaacga acgtggactc atccagacta ttggacgtgc
    61741 tgctcgtaac agtgaaggcc atgtcatcat gtatgcagac acggttaccc agtctatgca
    61801 acgtgctatc gatgaaactg cccgccgtcg gaaaattcag atggcctata atgaagagca
    61861 tggtatcgta ccacagacaa tcaagaaaga aatccgtgac ctgattgctg tgaccaaggc
    61921 agttgctaag gaagaggaca aggaagtcga catcaatagc ctcaacaaac aagagcgcaa
    61981 agaactcgtc aagaaactag aaaaacaaat gcaagaagcc gtcgaagtac ttgactttga
    62041 actggcggct cagatccgtg atatgatgtt ggaagtcaag gccttggatt aggggaatag
    62101 tatgatttat ttaagaaagt taaagagaga agatttgatg tctttatggg aaatggctta
    62161 ttcacaactt aatccagttt ggaaacagta tgatgctccc tattatgatg attatcagta
    62221 tttttcaaat tttaaagaat tcgaactaca aaaatcagaa tccattttaa gcaactcaaa
    62281 tcgccttggt atttttgttg atgataaact agttgggact gtttcgcgtt attgggtatg
    62341 taaacaaaca agatggatgg aattgggaat tggtatttat gataaaaaat tctggaacac
    62401 tggtattggg aaagttgcta tgttgcagtg gatagatagg acgtttcagg attacttgga
    62461 gttggagcat ctgggtttga caacttggtc agggaatctt ggtatgatga aacttgctga
    62521 aaaattaaga atgaaaaaag aagctcatat tccaaaagtt cgttattatc aaggtaaata
    62581 ttttgatagt attaaatatg gtattttgag agaagactgg gagaaaacaa atgacggtta
    62641 ttatcaaatc aatggaaact cctgaagaga tagaaggtaa gccccttgtt cactggcaaa
    62701 cgtggagaga ggcttatgat ggccttttgc ctgcagaatt tcaggagaca atgacattag
    62761 aaagatgtcg attctttagt caaaagtatc cagaaaatac attgattgcg atggatggta
    62821 tgaaggtagt tggttttatc agttatggca actttcgtga tgagactatt caagctggcg
    62881 aaattattgc tttatatgtt ttaaaagact attatggaaa aggtatcgca caaaagttaa
    62941 taaaagcagc tttgattgct cttaatcatt tttctgaaat tttcttatgg gtattgaaag
    63001 ataataagcg cgcaattgct ttctatcaaa aaatgggctt tacttttgat gaacaagaaa
    63061 agatacttga acttggaaag cccataaagg aaaaacggat ggtattctat tctaaataat
    63121 tttaaaaagt agaagctaat ggtactggta tcaagtctaa aaatttaata aattagaaag
    63181 tgagtaaatt tatgtctcga gcacaattaa cgattttaac aaatatttgt ctgattgaag
    63241 atctcgaagc tcagcgcgtg gtgatgcagt atcgcgctcc tgaaactaat cgctggtctg
    63301 gttatgcctt tccaggaggc catgtagaaa atggcgaatc tttcgcagag tctgtcattc
    63361 gtgaaatcta tgaagaaaca gggttgacta tccaaaatcc tcaacttgtc ggcattaaaa
    63421 attggccact agatacaggt gggcgctata ttgtcgtttg ttataaggca actgagttct
    63481 ctggtaccct tcgctcttca gatgaaggag aagtttcttg ggtgcaaaaa gaccagattc
    63541 caaacttgga tctggcctat gatatgctac ctttgatgga gatgatggaa gcatcggaca
    63601 aatctgaatt tttctaccct cgccgtacag aagacgattg ggaaaagaaa attttctaat
    63661 cctttactaa ataacctagc tgatccaagg cctcctcgat atagtggagg tcttgttgtg
    63721 tttcggcttc gactaggtgg taatggacac catctgtcaa ttcagataaa ggtttaaaat
    63781 cagaatgctc gacttgttct agaaaatgtt gaacgtctcg gcggcaagac agtttaagca
    63841 aggtttcaat ttctccataa acgggatggt caatcaaagt attctggaca tgcccaccat
    63901 tatcgacaat agcaaggagt tcctgaccga tttcttcaac ttcatgtttc actttgaaaa
    63961 gtttgtgaac ataaggattg gtatcaattt gcttatagat gtagccacga ttggtggata
    64021 ggataggagc gccatcggct ctcaaaattg caatgtcctg cacaatgacc tgacgtgtga
    64081 catgaaaatg ttccgccaaa ctttggccat taagggcttt aggagcttct ttcaagagtt
    64141 ggagcagggc ttgtttgcga tcttttgtca tagcttttcc ttttaacggc gttttcgaag
    64201 cactttatag acagctagtg ctaatgtata gtctaccata ctatggataa ttgtgccaaa
    64261 tccaactagt acaaatagaa catagaacat gttttctaca ttggtacccg aagttgcgta
    64321 aaaaaggaca caggctaata cttcagcaag ggcatgaaca acagccaaaa caaaattgaa
    64381 aacccaggaa gattttggtt tatctagggt atcggggaat ttttgtaggt aaagagatcc
    64441 taaagcacca aaagatatat gggaaaaagc ccgaaaaact ataaccatgg gatagccagc
    64501 catcaaaaat ccaaaactag aggctaggat gacaaaaact gccatcaagg gcgacaagaa
    64561 catggctata aaaatagcga tgtggctccc caaagtatag gaagcaggtg gaatgacaat
    64621 cttgaaaggc ataacaattg gaatcaaaat cgcaatagcc gttaaaaggg ctgtcattgt
    64681 cataaattgt gtctttttcc gtgtattcac aagaatctcc tttttaactg catatacact
    64741 agtatggtac aataaaccag acaataaagc aagaatttac ttgggtttat agatcatttt
    64801 ttagttaaaa gttatagtag atggaaacta gaatagtcca cctctacttc taaaacattg
    64861 ttagcgattt gactgtcctg atcgatttgt cctgttctta tttcgtttta ctatagtaaa
    64921 gatttcatta aaaagaaact gtatagagca aaatctccac cttcaggttt gaaagcggag
    64981 attgttttta ttttttcaag gtttgtagtc gtggaacaat ggctagggtt agaattgcag
    65041 aaatgaccaa ttcagcaatt gaatttgttg agataacggt tgccagaaga agttggatat
    65101 ttccattata aacatttcca aataggaaga agattcctcc aaggacaaag atagtatttg
    65161 tcaaggaacc aagggctcca gctaaaatca gaccagtctt gtttttcatc agtttataga
    65221 ctaagtaagg agttaaacca atcaaaatac gtgggacgat ggcaatgata gctgagtaga
    65281 tgtttccgtt tggtacgaag ggagagaaga ggtagcttgt cggtagaatc gtaatcgtgt
    65341 taaccgtcaa gctaagtaat cccatcaaaa atccaagtgt aaccccaact cgtggaccat
    65401 aaataatgct ggcaataatg acaggaatat gaacaatggt cggtttgatt ggaaatggaa
    65461 aaaggttaaa gataagtgag ctcagaaagt gtatcacgag catggtagca aaaaagatag
    65521 caatgggtgc aatattagag cgttttttca tcgatagttt cctttattct ttctaaaata
    65581 attgtgaggt cagctaaagc tcctcgtccg tggtctccac aagctagtag ggattcctta
    65641 ggagcaatca gctgatagcc gtaggtttct aatgttttca gattattctg agttactgga
    65701 tggtcataca tttttgtatt catagcagga gctattagtt tgggaatatg acttggtagg
    65761 gctagagctg tactggttac catgttgtcc gcaaatccgt gagctagttt tgcaatagtg
    65821 ttagcagttg caggtaccac gataaataaa tctgcttttt ttccaagttc gatatgattg
    65881 acctgatcag gatagggttc cttcatgaca tccaagtgga caggattctg tgagagtacc
    65941 tgtagtgtca aaggttggat aaactctgta gcagcctgag tcattaagac agtgacttga
    66001 tggccttgtt tttttagaga actgactaaa tctgccgact tataagaggc gattgaaccc
    66061 gttacagcca agagaatgtt tgccatagtt ttcctttcta agaatgatag gcttgaattt
    66121 tttcaaggag gagttctgca atttcttctt tagtctggac tgtttgaagc tgatttttct
    66181 caacaaatat agctcggtgc tgatctgctg aaatttgagt caggtcattc gcgatgatta
    66241 aatctgcttg attcttgata agactttttc gtgcaatgtc aaccagatga tcttcggtaa
    66301 catcaaccag cagtttgaaa ccaatcagat gaatagtggg attccattcc ttgactaggg
    66361 atatgatttt gggtgtcttt ttaaggaaca aaacctgaac ctcatcagtt gaagaaatct
    66421 tggcctgatg attctgcttg cttaaaaatt cttttagatt ggagctagcc tgaacttcct
    66481 caagccctgt catataaaca ggagtgtagt cagaaacagc cattgagtgg atcaagacct
    66541 gataatcctg aacacgttct tgcatttcta ttagaaggtc cttggtattg gtaatttctc
    66601 gaatacttag gttaggatga ggctctggct tcagagctcg ttttgtcgta attaaacaaa
    66661 cttcatgccc tgcagaaagc aaagtctctg tgataatttt ccccaagtga cctgtagaat
    66721 ggttagtgat agagcggacg ctatcgatag cttcactggt accgcccgat gtaactaaaa
    66781 ttttcatagc actattgtac acaaaaataa gcggtaagta aaatgaaagt gataaatttt
    66841 tggtaaaaac gaagatttac tatagtttca aactataaag ccatataaaa tttaagaaag
    66901 gactctaaaa gccttaaaaa cagagatatt tacgaacgtt tagagagttt taggatgtta
    66961 aaaatcttgt tttgtgatat aatgaattat catataagag gttagaggaa ttttgaatga
    67021 aaacagatat tgaaatcgca cagagtattg agttgaagcc aattgttgat gttgtagaga
    67081 aacttggtat ttcttatgac gatttggagt tgtacggaaa gtacaaggct aaactcagct
    67141 ttgataaaat tcgtgcagtt gagagcaatc cagtcggtaa attgatcttg gttactgcca
    67201 tcaacccaac acctgcaggt gaaggaaagt cgacgcttac cattggtctt gcggatgcct
    67261 tgaacaagat tggcaagaaa accatgattg ctatccgcga accgtctctt ggtccagtca
    67321 tggggatcaa gggtggtgct gctggtggtg ggtatgcaca agttctgcca atggaagaca
    67381 tcaacctcca ctttactgga gatatgcatg ctattacaac tgccaacaat gccctttctg
    67441 ccttgattga caaccacttg caccaaggga atgagctgga aattgatcaa cgtcgtatcc
    67501 tctggaaacg cgttgtggac ttgaacgacc gtgcgctccg ccatgtgact gttggtcttg
    67561 gtggtcctct aaacggtatt ccacgtgagg atggttttga tattacagtt gcttcagaaa
    67621 tcatggcaat tctttgcttg gcaacggaca tcgaggactt gaaacgtcgt ttggcgaata
    67681 tcgttattgg ttatcgctat gaccgtacgc ctgtttctgt aggtgatttg caggttgagg
    67741 gtgccttggc tttgattttg aaggatgcta ttaagccaaa cttggttcag acaatttacg
    67801 gtacacctgc ctttgtacac ggtggtccat ttgccaatat cgctcatggc tgtaactctg
    67861 ttttggcgac gacaacagcc cttcacttgg ctgattacac tgttactgaa gctggttttg
    67921 gtgcggacct tggtgctgag aaattccttg atatcaagac accaaacttg ccaacatctc
    67981 cagatgcagt tgtcattgtc gcaacccttc gtgcccttaa gatgaatggt ggtgtggcta
    68041 aagacgctct gactgaagaa aatgtagagg cagttcgtgc aggttttgct aacttgaaac
    68101 gccacgttga aaatatccgt aagttcggta ttccagcagt tgtagctatt aacgaatttg
    68161 tatctgatac agaagctgaa attgcagtct taaaagaact ctgtgcctca atcgatgtac
    68221 cagttgaatt ggctagtgtc tgggctgatg gagcagaagg tggagtagca cttgccgaaa
    68281 cagttgttaa gacaattgct gaaaatccag ctaactataa acgtttgtac gataatgccc
    68341 tttctgtcca agaaaagatt gaaaaaattg tcactgaaat ctatcgtggt agcaaagtga
    68401 actttgagaa gaaagctcaa acacaaattg ctcaaatcgt tcaaaacggt tgggacaaat
    68461 tgccaatctg tatggctaaa actcaataca gtttctcaga caatccaaat gcgcttggag
    68521 caccagaaaa ctttgaaatt accattcgtg aattggtacc aaaattaggt gcaggcttca
    68581 tcgttgcctt aactggtgat gttatgacca tgccaggtct tccaaaacgt ccagcagctc
    68641 tcaacatgga tgttgaaagc gatggaactg tactaggctt gttctagtgg attgaaattg
    68701 actttaagtg agtttggaaa taatatccaa gctcattttt tctcagactg caagcagttc
    68761 atcaataaga tttatactct tcgaaaatct cttcaaacta cgtcagcttc accttgccgt
    68821 aggtatatga tactgactct gtcagttcta tccacaacct caaaacagtg ttttgagcaa
    68881 cctgcggcta gcttcctagt ttgctctttg attttcattg agtataagta gatagaaaag
    68941 ttatatacta tctattgaaa atattataaa tcagatacaa agacaggtga aaccttctgt
    69001 gttatactag agatatgtta gatttgaaag aatacggtat cgtcatgtgg ccggaggaga
    69061 aagtcatttc tttccgtgag aaacttctcg cttggtatga tgaaaacaaa agagatttgc
    69121 cttggaggag aagtaaaaat ccttatcaca tctgggtatc tgaaatcatg cttcagcaga
    69181 ccagggtgga tacagttatc ccttactacg aaagattcct ggactggttt ccaactgtcg
    69241 aaagtctggc aactgcgcct gaggagagtt tactgaaagc ttgggagggc ttgggctatt
    69301 attctcgagt tcgcaatatg caggctgcag cccagcagat tatgactgac tttggtggcc
    69361 aatttccaaa tacctatgaa ggaatttcca gcttgaaagg gattggacct tacacagcag
    69421 gagccatttc cagtattgct tttaacttgc ctgagccagc tgtagatggt aatgtcatgc
    69481 gggtcttggc gcgtctgttt gaagtcaacc acgatattgg gattccaagt aatcgaaaaa
    69541 tttttcaggc aatgatggag atcttgatta atccggatcg tccgggtgat tttaatcaag
    69601 ccttgatgga cttagggtct gatattgagt ctcctgtaaa tcccagacct gaagaaagcc
    69661 cagtcaagga ctttagtgcg gcatatcaga atggaaccat ggaccgttat ccaattaaat
    69721 ctcctaagaa aaagccggtt cctatttatc ttaaagcatt agttgtgaaa aattctcaag
    69781 gacaattttt acttgaaaaa aatgaaagcg aaaagctctt ggcaggtttt tggcatttcc
    69841 cccttataga agttgataac ttttcgcaag aagagcagtt tgacctcttt catcaggttg
    69901 cggaagaaag tgtgaacttt ggccccagtc cagaagagag tttccagcag gactatgacc
    69961 tagatgttga ttggcttgat gtttgttttg atacagtcca gcatgttttt agtcatcgaa
    70021 aatggcatgt acagattgta gcaggtcagg tgagtgactt ccatgatttt tcagataggg
    70081 aagttcgttg gctttcacca gaagaattca agaattaccc acttgccaaa ccccaacaaa
    70141 aaatctggca ggcttatgca caagccaact tagacagtag ccaagactag ctattgtgtc
    70201 ttctgactat tttttggtat aatagtagag aaaaaggtga acatatgaaa aaaatactaa
    70261 ttgtagatga tgagaaacca atctcggata ttatcaagtt taatatgacc aaggaaggtt
    70321 acgaagttgt aactgctttt aatggtcgtg aagcgctaga gcaatttgaa gcagagcaac
    70381 cagatattat tattctggat ttgatgcttc cagaaattga tggtttagaa gttgctaaga
    70441 ccattcgtaa gacaagcagt gtgcccattc ttatgctttc agccaaagat agtgaatttg
    70501 ataaggttat cggtttggaa cttggggcag atgactatgt aacgaaaccc ttctccaatc
    70561 gtgagttgca ggcgcgtgtt aaagctcttc tgcgtcgttc tcaacctatg ccagtagatg
    70621 gtcaggaagc agatagtaaa cctcaaccta tccaaattgg ggatttagaa attgttccag
    70681 acgcctacgt ggctaaaaaa tatggcgaag aactagactt aacccatcgt gaatttgagc
    70741 ttttgtatca tttagcatcg catacaggtc aagtcatcac gcgcgaacac ttgcttgaga
    70801 ctgtctgggg ttatgactat tttggtgatg tccgtacagt tgatgtgact gtacgacgtc
    70861 tgcgtgagaa gattgaagat acgcccagcc gaccagagta tatcttgacg cgccgtggtg
    70921 tagggtatta catgagaaat aatgcttgat ttactgaaac aaaccatttt taccagagat
    70981 tttatcttta tcctgatttt gttaggtttc atccttgttg tgaccctctt attactggaa
    71041 aatagacgtg ataatattca gttgaagcaa atcaatcaaa aggttaaaga tttgattgca
    71101 ggagattatt ccaaggttct tgatatgcaa ggtgggtctg aaatcaccaa tattaccaat
    71161 aatttgaatg acttgtcgga ggttattcgt ctcactcagg aaaatctaga acaagagagt
    71221 aagaggctaa atagtattct gttttatatg acagatgggg ttcttgcgac caaccgtcgg
    71281 ggtcagatta tcatgattaa cgatacagcc aagaagcaac tggggttggt taaggaagat
    71341 gttctgaata gaagcatttt ggaattgctc aagatagaag aaaactatga attgcgtgat
    71401 ttgattaccc aaagtccaga attgttgcta gattcccaag atatcaatgg cgaatatttg
    71461 aaccttcgag ttcgctttgc cttgatacgt cgagagtctg gctttatttc aggtttggtg
    71521 gctgttttgc atgatacgac ggagcaggag aaggaagaac gcgaacgaag actctttgtt
    71581 tccaatgtta gccatgagtt acggactcct ctgactagcg taaaatccta tcttgaagcc
    71641 ttggatgagg gggctttgtg tgaaactgta gcaccagact ttatcaaggt ttctcttgat
    71701 gagaccaacc gtatgatgcg catggtgacg gatctcctcc atctttcacg tattgataat
    71761 gctaccagtc acctagatgt ggaactgatt aacttcactg cttttattac ctttatcctc
    71821 aatcgttttg acaagatgaa aggacaggaa aaggagaaaa aatatgagtt ggtgagagat
    71881 tatcccatca attctatctg gatggaaatt gatacagata agatgacgca ggttgtcgac
    71941 aatattttaa ataatgctat taagtattcg ccagatgggg gtaaaatcac tgtcagaatg
    72001 aagacaactg aagaccagat gattttatcc atttctgacc acggtttggg gattcctaag
    72061 caggatttac cacgtatctt tgaccgtttc tatcgtgtgg atcgtgctag aagtcgtgca
    72121 caaggtggta caggtctagg actgtctatc gctaaagaaa ttatcaaaca acataagggc
    72181 tttatttggg ccaagagtga atacggcaag ggttcaacct ttaccattgt gctcccttat
    72241 gataaggatg cagtgaaaga agaagtatgg gaggatgaag tagaagacta gaatgagtga
    72301 aataggcttt aaatacagta ttttagcgtc gggttccagt ggaaattctt tttatctgga
    72361 aacctcaaaa aagaagcttt tagtagatgc aggcttgtct ggcaagaaaa ttaccagtct
    72421 gctagctgaa attaaccgta agccagaaga cctggatgcc atcttgatta cccatgagca
    72481 ttcagatcat atccatggag taggcgtttt ggctcgcaag tatggtatgg atctttatgc
    72541 caatgaaaag acctggcaag ctatggaaaa tagtaaatat cttggcaagg tggattcttc
    72601 gcaaaagcat atttttgaaa tgggtaaaac caaaaccttt ggagatatcg acatcgagag
    72661 ttttggtgta agccatgatg cagtcgcacc gcagttctat cgctttatga aggatgataa
    72721 gagttttgtc ctcttgacag atacaggtta tgtcagtgac cgtatggcgg gcattgtcga
    72781 aaatgcggat ggttatctta tcgaggccaa ccatgatgta gagattttgc gatcaggttc
    72841 ttacgcttgg cgcctcaaac aacgaatcct atctgacctt ggtcaccttt ctaacgagga
    72901 cggtgctgaa gctatgattc ggacgctagg aaatcgtact aagaagattt accttgggca
    72961 tttatctaag gaaaacaata tcaaggaact ggctcatatg accatggtca atcagctggc
    73021 tcaagctgat ctgggagtcg gagtagactt taaggtttat gatacctcac cagataccgc
    73081 aacaccattg acagagatat agaaagaacg ctgagaaggt gttcttttta tattgactgg
    73141 acacctaaaa agtaatacaa tggtgttacc attaaaaaag ggagcacaaa agatgactac
    73201 tattacatta aaagtttctg aagctgataa aacatttatg aaagcaatgg ctaagtttga
    73261 aggagtttcc ctttcggaac ttattcgcac caaaactctt gaagccctag aagatgaata
    73321 cgatgctcgt gtggcagatt tagcctatca agagtattta gaagacttgg aaaaaggagt
    73381 tgaacccatt acttgggaag aaatgatgca tgatttaggc ttgaaggatg aataatttgt
    73441 ataaattagt tccaacaaga cgttttatca agcaattgaa aaaattggac cgttatacgc
    73501 agaagctaat tacaaactat ttacaaacca atgttttgga agatccaaga cgacacggaa
    73561 aggctttggt tggtaatcgc gttggtcaat ggcgctatag aattggtaat tatcgagtta
    73621 tcgtacaaat tgtagatgat gaattagttg ttgctactct agaagttggt catcggagag
    73681 atatttatta aattaaagct gagtaataac agtatagaaa gtaaggagag taaaaatttg
    73741 aagaaaaaat ggttttttgc agattattat gacacaacaa ttattttact tgctttaatc
    73801 tctgttattc tggtattact tggatttgct gagatgattg atttggacaa tccgccttat
    73861 agtattattg atttagtaat ctggggtgtt tttgtaattg attatagttg gcgctttttt
    73921 acgactaaaa gaaaatggcg ctttattctt gaaaatattt ttgatttatt ggctattctc
    73981 cctttaaatg ctatttttac agtgtttcga ttagggcgta tctttcgttt agctaaacta
    74041 acaaaattac tgaaactgac tcgtttactt agaataattg gacttacagg taaattagaa
    74101 agaaaaatta gtagattctt acggacaaat ggcctgattt atatcttgta tgttaatatc
    74161 tttattgttc tagtagggag ttcgatttta tccgttgttg aagaaaaatc cttctcagat
    74221 agtctttggt gggctcttgt gacagtaact actgttggat atggggatat tgttcctgct
    74281 tccatttttg ggaaatggct agcagtttta ctgatgcttg tcggtattgg aacaataggg
    74341 atgttaacaa gtgctttgac gaactttttt gtaaaggata atccagatga acagataaaa
    74401 cttgataaac tcaaagatga attatcgagc caaagaatat tactagagaa acaatctaaa
    74461 aagatagaag aactacataa aatgatacaa gatttgattg aaaaaacata ataaaaataa
    74521 agatgagaca aagtttgagc tgaggagaaa tcaagtaagt tttgacacaa tagaacgcat
    74581 attatcaggt ataaaaactt gatactatgc gttttataga gaaataaaat aaaatctgaa
    74641 caaatcaatt aggaatttaa agcattttat aacaacgttt tagagtgatg gggtgctatt
    74701 tcaacttcaa cctactataa tacagaaaaa aacaactccc tgatgattca aggagttgtc
    74761 tatagttaaa ttagttttta gaagcttctt ggaattctgg atttttccat gcttcgtcaa
    74821 taatagcttg caattcttta gcagatgctt gcattttttg agtttctgca tcgttcaatg
    74881 gaatgtttac tggacgaacg ataccatgtg caccaacaac agctggttga ccgataaaga
    74941 cattctcaac tccgtataga ccttcttgga atactgaaag tggaagtact gcgttttcat
    75001 cgtcaaggat tgctttagtg atacgagcaa gggctactgc gataccgtag tatgttgcac
    75061 cttttttgtt gatgattgtg taggctgcat cacgaacacc ttcgaacaat tcaatcaatt
    75121 cagcttcttg aacattttga gtgtctttaa ggaattcttc aaggtttaca ccagcgatgt
    75181 tagcgtgtga ccaaacagcg aactcagagt caccgtgttc acccatgatg taggcgtgca
    75241 ctgaacgagc atccacatcc aatttttcag caagtgcttg acggaaacga gctgagtcaa
    75301 gtgaagtacc tgaaccgata acgcgttctt tagggaaacc agagaatttc caagttgagt
    75361 aagtcaaaac gtcaactggg ttagcagcaa caaggaagat acctttgaaa ccagattcaa
    75421 caacttgagt tacgattgat ttgttgatag caaggttttt acctacaagg tcaagacgag
    75481 tttcacctgg tttttgaggt gcacctgcag taatcacaac aaggtcagcg tctgcacagt
    75541 cagagtattg agctgcatag atttttttag gtgaagtgaa ggcaagggcg tgactaaggt
    75601 caagcgcatc accaacagct ttttcatgca attgtggaat ttcgataatt ccaagctctt
    75661 gtgcaattcc ttggttaaca agtgcaaaag cgtaagatga acctacagca ccatcaccga
    75721 caaggataac ttttttgtgt tgtttagttg aagtcattgt tttaaacatc tccttaattt
    75781 tattagggga ttttccctag acaacttcat tctatcactt ttaaaaaact ttgtcacgaa
    75841 tatgccttat agttctcgat gtaaacgttt tagtggttta gaggctgaaa tagatgggaa
    75901 tttatggtat aatgttgtta cttactaatt gtgaaatgag gcatttatta atgcaggata
    75961 aaaatttagt gaatgtcaat ctgacaaagg agatgaaggc aagttttatc gactacgcca
    76021 tgagtgttat cgtagcgcga gctcttcctg atgttcgaga tggcttaaaa cctgttcacc
    76081 gtcgcattct ctacggaatg aatgaattgg gtgtgacccc agacaaaccc cataaaaaat
    76141 ctgctcgtat tacaggggat gtcatgggta aatatcaccc acacggggat tcctctattt
    76201 atgaagccat ggtccgtatg gctcaatggt ggagctaccg ttacatgctt gtagatggtc
    76261 atgggaattt tggttccatg gatggagata gtgctgccgc tcaacgttat accgaggcac
    76321 gtatgagcaa gattgctctg gaaatgcttc gtgatatcaa caaaaataca gttgatttcg
    76381 ttgataacta tgatgccaat gaacgggaac ccttggtctt gccagcgcgt tttccaaacc
    76441 ttttggttaa tggagcaact ggtatcgcgg ttgggatggc aaccaatatt ccacctcata
    76501 atctgggtga aaccattgat gcagtgaagt tggtcatgga taatcctgaa gtgactacca
    76561 aggacttgat ggaagtcttg cctggaccag attttccaac tggtgctctt gtcatgggga
    76621 aatcaggtat ccataaggct tatgaaacag gtaaaggttc gattgcccta cgttctcgta
    76681 cagagattga aacgactaag actggtcgtg agcgcatcgt tgtaacagaa tttccttaca
    76741 tggtcaataa aaccaaggtg catgagcata ttgttcgctt ggttcaggaa aaacgcattg
    76801 agggtatcac agcagtacgt gatgagtcaa accgtgaagg tgttcgattt gttattgaag
    76861 tcaagcgcga cgcctcagcc aatgttattc tcaataacct cttcaaaatg acccaaatgc
    76921 aaaccaattt tggtttcaat atgctcgcta tccaaaatgg tataccgaaa attttgtctc
    76981 ttcgtcagat tttggatgct tatatcgagc accaaaaaga agtggttgtt cgtcgtacac
    77041 gttttgataa ggaaaaagcg gaagcgcgcg ctcatatctt agaaggtctc ttgattgcgc
    77101 tagaccatat cgacgaagtg attcgtatca tccgtgctag tgaaacggat gcggaagctc
    77161 aagctgagtt gatgagcaag tttaagcttt ctgaacgtca aagtcaagct atccttgata
    77221 tgcgtcttcg tcgtttgaca ggtttggaac gcgataagat tcaatctgag tatgatgacc
    77281 tcttggctct gattgcggat ttagcagata ttcttgctaa gcctgaacgt gtttctcaaa
    77341 ttatcaaaga cgaattggat gaagttaaac gtaaattttc tgataagcgc cgtacagagt
    77401 tgatgattgg acaggtcttg agtctcgagg atgaggactt gattgaagaa tcggatgtct
    77461 tgattaccct ttctaacaga ggctacatta agcgtttgga tcaggacgag ttcactgctc
    77521 aaaaacgtgg gggtcgtggt gtccaaggaa cgggagtgaa agatgatgac tttgttcgtg
    77581 agttagtgtc aactagcacc catgatcatc tgctcttctt cacaaacaag ggacgtgtct
    77641 atcgtcttaa aggttatgaa attcctgagt atggtcggac tgccaaaggg ctaccagtag
    77701 tcaatctctt gaaattggat gaagacgaaa gtattcagac ggttatcaat gttgagtctg
    77761 atcgcagtga tgatgcttat ctcttcttta caacccgtca cggtattgtg aagagaacca
    77821 gtgttaagga gtttgccaat attcgtcaaa atggtctcaa agcgctgaat ttaaaggatg
    77881 aagatgagtt aatcaatgtc ttgttggcag aaggagatat ggatattatc attggtacca
    77941 agtttggtta tgcagttcgc tttaatcaat cagccgttcg tggtatgagt cgtatcgcca
    78001 ctggtgtgaa aggtgttaac cttcgtgaag gagacacagt tgttggtgcc agcttgatta
    78061 ctgatcaaga tgaggttctt attatcacag aaaaaggata tggtaagcgt acagtcgcta
    78121 ctgaataccc aacaaaaggt cgtggtggta agggaatgca gacagctaaa attaccgaaa
    78181 aaaatggctt gctggccggt cttatgactg ttcaagggga tgaggatttg atgattatca
    78241 ctgatacagg tgtcatgatt cgaaccaatc ttgccaatat ttcacaaaca ggacgtgcaa
    78301 ctatgggagt taaagtaatg cgcctggatc aagatgctca gatagtgact ttcacaacgg
    78361 ttgcggtggc agaaaaagaa gaagttggga cagaaaacga aacagaaggt gaagaataat
    78421 gtctcaaaaa aataataaaa agaaaaacaa gcgaaaaaat ctgctgacaa atatcctagc
    78481 aggatttctg atattactgt cactggcttt gatttttaat actcaaattc gaaatatttt
    78541 catagtctgg aataccaata agtatcaagt tagccaggta tcaaaagaaa aattagaaga
    78601 aaatcaggat acagaaggca attttgactt tgattctgtc aaagctatct cttcggaagc
    78661 tgttctaact tctcaatggg atgctcaaaa attaccagtt attgggggaa ttgcaattcc
    78721 tgaattggaa atgaatttgc cgatttttaa aggacttgat aatgttaatc tcttctacgg
    78781 agctggtaca atgaaacgcg agcaagtaat gggagaagga aattatagtc tagctagtca
    78841 ccatatcttt ggtgttgata atgctaataa aatgttattt tctcctttag ataatgctaa
    78901 aaatggcatg aagatttatc taaccgataa aaataaagtt tatacttatg aaatacgtga
    78961 agtcaaacgt gtgacaccgg atcgtgttga tgaagttgat gatagagatg gggtcaatga
    79021 aatcacatta gtaacctgtg aagaccttgc tgctacagaa cgtattattg tcaaaggtga
    79081 tttgaaagaa acaaaagatt attcacaaac atctgatgaa attctaacag ctttcaatca
    79141 accatataaa caattttatt aatacaaatc agtgaaatca tggatttcac tgatttttta
    79201 agattttcat aaaaatatag taaaatgaaa taagaatagg acgaatcgtt caggacagtc
    79261 aaatcgattt ctaacaatgt tttagaagta gaggtgtact attctagttt caatctacta
    79321 taaactttta tgaaatacag aaaacgcttc ctaaaaccta aagtttgtga tataattatc
    79381 aagaaaaaag atttaggagt ttattatggt ttcttcagaa tttatctcaa agattgaatt
    79441 tgcttgcaat aagaaagaaa gtctttatag tcaaagcaaa tttaagtatg cgattcgttc
    79501 gatgttcgca ggtgcatttt taaccttcag tactgctgca ggtgcagttg gggctgactt
    79561 gattaataaa attgcaccag gtagtggacg cttcctcttt ccattcgttt ttgcttgggg
    79621 cttggcctac attgtttttt tgaatgccga gttggtcact tcaaacatga tgttcttgac
    79681 tgctggtagt ttcttaaaaa aaatctcttg gagaaaaaca gctgagattt tactatactg
    79741 taccttgttc aaccttatcg gagccttgat agcagggtgg ggctttgctc attcggcagc
    79801 ctatgcgaat ctgacacacg atagtttcat ctcaggtgtt gttgagatga agttaggccg
    79861 ctcaaatgaa ttggtcttgc ttgaggcgat tttggcaaat attttcgtaa atattgcgat
    79921 tctgtcattt attttggtca aagatggtgg tgccaaactt tggcttgtgt tgtcagctat
    79981 ttacatgttt gtattcttaa caaacgagca cattgcggcg aactttgctt ctttcgcgat
    80041 tgtgaaattc agtgttgctg cggattcaat tgccaacttc ggtgttggaa atatgcttcg
    80101 ccactggggt gtgactttca tcggaaactt tatcggagga ggcctcttga tgggtcttcc
    80161 atatgccttc ctcaataaaa acgaagatac ttatgtagat taagaaaatg agcacgattg
    80221 agtcgtgctt ttttcatttt caaaataagg taatagctat ttcttatatc aaaatataga
    80281 aaactgatat ttgtaaacta taactcaagg tgctacaata tccttaataa aatgatatgg
    80341 aggtcacctt atgacttgtg attttaaatt tgaaactcta caactacatg ctggtcaagt
    80401 tgtggctcca gctactaagt ctcgtgcagt gccgatttat caaacaacat cttttatttt
    80461 tgatgacacg taggaaggtg ctgatctgtt tgccttgagg aaaccaggga acatttatac
    80521 tcgtatcacc aatcctacaa cagctgccct tgaaggtggt gttgaagcgc tagcaacagc
    80581 atcaggtatg actgcagtga cttatacgat tttggcgctt gcccatgctg gtgaccatgt
    80641 agtggctgct tcgactattt acggtggaac cttcaatctt ttgaaagaac cccttcctcg
    80701 ttatggtatc acaacaacct ttgtcgatgt tgataatttg gaggaagtag aagcagctat
    80761 caaagacaat accaagcttg tcttgattga aaccttgggt aactccttga ttaatattcc
    80821 agacctggaa aaactggcag agattgctca taaacatcaa atcccacttg tgtcagacaa
    80881 tacttttgca ataccttatt tgattaacgt cttctctcat ggcgttgaca ttgccattca
    80941 ctctgcgact aagtttatcg gtgggcatgg tacaactatt ggaggaataa ttgtcgatag
    81001 tggtcgtttt gactggacgg cttcagggaa attccctcaa tttgttgacg agggtccaag
    81061 ctgccacaat ttgagttata cttgtgatgt gggtgcagca gcctttatta tagctgttcg
    81121 agttcaattg cttcgtgata caggtgcagc cttgtcacca ttcaatgctt tcctcttgct
    81181 acaaagactt gaaacctctt cacttcgtgt ggaacgccat gtacaaaatg ctgagacaat
    81241 tgttgatttt cttgtcaacc atcctaaggt agaaaaggta aattatccaa aacttgcaga
    81301 tagtccttat catgccttgg ctgagaaata cttgccaaaa gatgtcggtt caatctttac
    81361 cttccatgtc aaaggtggcg aggaagaagc acgcaaggtc attgataatt tagaaatctt
    81421 ttctgacctt gcaaacgcgg cagatgctaa atcgcttgtt gtccatccag caacaaccac
    81481 tcacggtcaa ttgtcagaaa aagacctaga agcagcaggt gtcacaccaa actaaattcg
    81541 tttgtcaatc ggtcttgaaa atgtagaaga tttgattgaa gacttgcgct tggccttgga
    81601 aaaaatttaa agtaaaagaa gataaacagt gggcttcgac tcactgtttt tgattttccc
    81661 tcaggcatga tataatggtt aaagaagtct agaaagagga acgatatgaa cgaaatcaaa
    81721 tgtcccaact gtggggaagt ctttacagta aatgagagtc agtatgccga actcttgtcc
    81781 caagtgagaa cggcagagtt tgataaggaa ctacacgata ggatgaagca ggaactggcc
    81841 ttggctgagc aaaaggccat gaatgagcaa cagactaaac tggctcagaa ggatcaagaa
    81901 attgcgcaat tacagagtca gatccaaaac tttgatacag aaaaagaatt ggccaagaaa
    81961 gaggttgaac agacaagcca tgaggctctc ttggctaagg acaaggaagt acagctctta
    82021 gaaaatcagt tggctacctt gcgtttggag catgaaaatc aactgcaaaa gaccctttct
    82081 gacctagaaa aagaacggga tcaggttaaa aaccaactac ttttgcagga aaaggaaaat
    82141 gaattatctt tggcttctgt taagcaaaac tacgaagccc agctcaaggc agctagtgaa
    82201 caagtcgagt tttataagga ttttaaggct caacaatcta caaaagcgat tggggaaagc
    82261 ctagaacagt atgcagagag tgagtttaac aaggttcgta gtttcgcctt tccaaatgct
    82321 tactttgaga aggataacaa ggtctcttcg cgtgggtcta aaggggactt tatcttccgt
    82381 gagtgtgatg aaaatggagt tgaaatcatt tctatcatgt ttgagatgaa aaacgaagca
    82441 gacggaacag agaagaagca caagaatgca gatttttaca aggaattgga caaggaccgt
    82501 cgggagaaga actgtgagta tgccgttttg gtgaccatgc ttgaggccga taatgactac
    82561 tttaacacag ggattgttga cgtcagccac gagtatgaaa aaatgtatgt tgttcgtcct
    82621 caattcttta tccagttgat tggtctctta cgtaatgcgg cgctaaattc cctaaaatac
    82681 aagcaggagt tggccttggt tcgcgagcaa aatattgaca ttacgcattt tgaggaagac
    82741 ttggatgcct ttaagctagc ttttgctaag aactataatt cagcttcgac taactttgga
    82801 aaagctattg atgaaatcga caaggccatc aaacgcatgg aagaggttaa gaaattcctg
    82861 actacatctg aaaaccaact ccgtctagct aacaacaaat tggaagatgt ctctgttaaa
    82921 aaattgaccc ggaaaaatcc aacaatgaaa gcgaagttcg aagcactgaa gggggagtag
    82981 aaagcaaaaa tgaacggtat tatcaactta aaaaaagaag caggaatgac ctcgcatgat
    83041 gcggttttta aactgcgtaa gattttggga accaagaaaa ttggtcatgg tggaaccttg
    83101 gatccggatg tggtgggtgt tttgccgatt gcggttggca aggcgacacg catggtcgag
    83161 tttatgcagg acgagggtaa gatctatgag ggggaaatca ttctgggcta ttccacgacg
    83221 actgaggatg ctagtgggga agtggtcgca gaaacccctg ttttgtctcc cttggatgaa
    83281 aagcttgttg atgaagcgat tgctagcttg actgggccta ttactcagat tccccctatg
    83341 tattcggcag ttaaggttaa tggtcgcaag ctctatgagt atgcgcgtgc tggtcaggaa
    83401 gtggagcgtc cagaacgtca ggtgaccatt tatcaatttg agcgaacaag tccgatttct
    83461 tatgatggcc aacttgcccg attcactttt cgtgtaaaat gcagtaaagg gacttacatc
    83521 cgtactttgt cagttgattt gggtgaaaag cttggttatg cggctcatat gtcccatttg
    83581 actcgtacta gtgctgctgg cttacaatta gaagacgctc ttaccttgga ggaaattgct
    83641 gaaaaagtag aggctgggca attagatttt ctccatcctt tagagattgg gacaggtgac
    83701 cttgtcaaag ttttcctaac tccagaagag gctacagaag ttcgctttgg tcgttttatt
    83761 gagctagacc aaacggacaa agaactggct gcctttgaag atgataaatt gttagccatt
    83821 ctagaaaaac ggggcaatct ctataagcca aggaaggttt ttagctagat cgtttaggaa
    83881 taaaaatcgg gtgatagata acaattgctt gataaacccc catactaata gtagaatggt
    83941 tttgggaatt ataatattcc aattgttgcg agttgtagat actcaaataa tctatataga
    84001 aatttagagg tgtgaaatga agcaacttaa aattctttca gataaatatt tagagtccat
    84061 gacaggttct ggtgggaact taggtctagg atttggtgtg ataattccat gatgtgaaat
    84121 gagtttcgag aaagggtgga gcaacttctt caacaaaaag aaataaatga aaatagtgag
    84181 ttgagtcacc tgtttcgtct tgctatacaa aatttagaca gaaatgaaaa ataccaatcg
    84241 gtcatggcca atttgagtca agggttgtca ctttacctca tgacgcatca ttaccaggca
    84301 cctaagtctg tcattgattt tggtttatgg attgccaaag ctcctagcca ggaaagaggg
    84361 agactggctt tcttgcagat gcttgctcaa accctacagg gctttcgtta aaactgtcga
    84421 acatcagagg gaagactctg gtgttttttg ctgatgagac tataaatttt gtaaaaaatg
    84481 tgatagaata gacgacggat aaaataacgg aggatagcat gcaaaataga ccaatcatta
    84541 ttggagtgac aggtggttct ggtggtggta aaaccagtgt ttcaagagcc attttatcgc
    84601 attttcctga tgaaaagatt tccatgattg agcatgattc atactacaag gatcagtctc
    84661 atttgacctt tgaagagcgt gtcaaaacca actatgacca tccttttgcc tttgatacag
    84721 acttgatgat cgagcagatt aaggaattgt tggcagggcg tccggtggac atcccgacct
    84781 acgactatac agagcataca cggagtagca agacctatcg tcaggagcct caagatgtct
    84841 ttatcgttga gggcattttg gtcttggagg acaagcgtct gcgcgatttg atggatatca
    84901 agatttttgt ggatacggat gacgatgtgc gtattattcg tcgtatcaag cgtgatatgg
    84961 aggaacgtgg ccgtagcctt gatagcgtta ttaaccagta cttaggtgtg gtcaaaccaa
    85021 tgtaccacca gtttatcgag tcaactaagc gttatgctga tatcgtcatt cctgaagggg
    85081 ttagcaatac cgtggctatc gacctgttga cgaccaagat tgcaaagatt ttggaagaag
    85141 ctcgaaacag caaataatca catgtggagg ccttgcctcc tttttctatt tttccctcat
    85201 aatggtacat aaatggagat ttttaggcat atttttggta taataatacc cataaaagag
    85261 caagtaaatg aatagtaggt ggagatggaa aagtatttat cggtaacaac tttgaccaaa
    85321 tatctgaaaa tgaaattcga taaagaccca tacttggaac gggtctattt aactggtcaa
    85381 gtttccaact ttcgtaaacg acctactcac caatatttct ccctaaagga tgaccatgca
    85441 gttattcaag cgaccatctg gtctgggatt tatcagaaat tagggtttga cctggaagaa
    85501 ggaatgaaga tcaatgtgat tgggcgtgta caggtctatg aaccaagtgg tagctactcc
    85561 atcatcattg aaaaagctga gcctgatggg gttggggcgc ttgcgattca gtttgaacaa
    85621 cttaagaaaa aattgacaga agaaggcctg tttcaagaac gcttcaagca agctctaccc
    85681 caattttcta agagaattgg ggtagtaacc agccgtagtg gagccgttat tcgagatatt
    85741 atcacgaccg tcagcaggcg attcccaggt gttgacatcc ttctttatcc taccaaggtt
    85801 caaggtgaag gggctgcgga ggaaattgct agaaatattg cgcgtgctaa tcaacgggac
    85861 gatttggatt tgctcattat tggtcgtgga ggtggttcta ttgaggatct ctgggccttt
    85921 aacgaagaaa ttgtggtacg agctattttt gaatctcgtt tgccagttat ctctagtgtg
    85981 gggcatgaga cggatgtgac cttggcagat tttgtggcag atcgacgcgc tgcaacgcca
    86041 acagcggcgg ctgaactggc aacacctgtg accaagttgg atgtattagc tcatttgcaa
    86101 aatcaggaaa aacggatggc aacggcagtc cgaaatgttc tatctaagaa acaagaggct
    86161 ttgaaaaaat gcagtcagtc tgttatcttt agacaacctg agcgcttgta tgacggttat
    86221 ttgcaacgct tggaccaact gcaactgcgt ttgaaacaaa gtttgcgaac tcggatttct
    86281 gataacaaac aattagttca agcaagaact catcaattag tacaattatc acctgttacc
    86341 aaaatccaac gctatcaaga ccgtttagga cagttggaca agctcttagg tagccaaatg
    86401 gcgttagttt atgacgccaa ggttgctgag gccaagcgac tttcggaagc tttgctcatg
    86461 ttggatacta gccgaatcgt ggcgcgtggt tatgctattg tcaaaaaaga agagtccgtt
    86521 gtagattcgg ttgagagttt gaagaaaaaa gaccaagtaa cgcttttgat gcgagatggt
    86581 caagtagaat tagaggttaa agatgtcaaa acaaaagaaa tttgaggaaa atctagcaga
    86641 actggaaacc attgtccaaa gtttggaaaa tggtgaaatt gctctggaag atgcgattac
    86701 tgcctttcaa aagggcatgg tcttgtcaaa agagctccaa gctacgctgg acaaggctga
    86761 aaagaccttg gtcaaggtca tgcaagaaga cggaacagaa agtgattttg aatgaaaaag
    86821 caagaaaaat tagctcttgt cgagtcggct ttggaagatt tttatggaga ccagcagttt
    86881 gcctctagtt tacgggagtc tgttctctat tctattcatg ctggtggcaa gcgtattcgg
    86941 ccttttctct tgttagaagt tctggaatcc ttgcaggtta ccatcaaacc tgctcacgcg
    87001 caggtagcta ctgccttgga gatgattcat acagggagct tgattcacga tgaccttcct
    87061 gctatggatg atgacgatta tcgaagaggg cggttaacca atcacaagaa attcggtgaa
    87121 gctatggcca ttttggctgg agatgcctta ttcttagacc catatgcctt gattgcgcag
    87181 gcagatttgc caagtcagat caaggtggac ttgattgcca acttatccct tgcttcaggt
    87241 agtctgggta tggtggcagg gcaagttttg gatatggagg gcgaacacca gcacttgtct
    87301 ctggaagaac ttcagactat tcatgccaat aagactggga agttactagc ctatcccttc
    87361 caagcggcag ctattatagc tgaattgtca cctgaaatgc aggtgaagct gaaaactgtg
    87421 ggtgaattga ttggacttgc ttttcaagtc agagatgatg tactggatgt gacagctagt
    87481 tttgaggaaa tcggcaagac acctcaaaag gatctgcagg cagaaaaatc aacctatcct
    87541 gccttgttgg gcttggaaga gtccattgcc ttttgtaacc aaaccctgga tcaagctaat
    87601 gaaaaattag aagaaattgc ccagcagctt ccctttgaaa cagaatcgat tgtaagtgta
    87661 gtagaaagtt tgagaatcaa tggctaagga aagagtggat gtactagctt ataaacaggg
    87721 gttgtttgaa acgagagagc aggccaagcg aggtgtgatg gctggtctag tcgtagcagt
    87781 ccttaatgga gaacggtttg acaagccagg agagaaaatt ccagatgaca ccgaattaaa
    87841 actcaagggg gagaaactca agtatgtcag ccgtggtggt ttgaaactgg aaaaggcctt
    87901 gcaggtcttt gatttgtcgg tggatggcgc gactacgatt gatatcgggg cctctactgg
    87961 aggttttacc gatgtcatgc tacagaatag tgccaagttg gtctttgcag tcgatgttgg
    88021 taccaatcag ttggcttgga aattacgcca agacccacga gttgtcagca tggagcagtt
    88081 caattttcgc tatgctgaaa agactgattt cgagcaggag ccgagctttg ccagtattga
    88141 tgtgagtttc atttccctta gtctgatttt gccagccttg cacagtgtct tggctgatca
    88201 aggtcaggtg gtagcacttg tcaaacctca gtttgaggca ggacgtgagc agattgggaa
    88261 aaatggaatt attcgagatg ctaagattca tcagaatgtc cttgaatctg taacagctat
    88321 ggcagtagag gcaggttttt cagtccttgg cttggacttt tctcccatcc aaggtggaca
    88381 tggaaatatt gaatttttag cgtatttgaa aaaagaaaag tcagcaagca atcagattct
    88441 tgctgagatt aaagaagcag tagagagggc gcatagtcaa tttaaaaatg aataaaaaag
    88501 aaagacttga aaaaattaga agattggtga cagattatca aatcggcacg caagaagaaa
    88561 ttgtagaaca tttgaaagaa gcaggtatca ctgccactca ggcgacggta tcccgagata
    88621 tcaaagagtt aggtattgtc aaaattcctt tgagagacaa cacctatgtc tacgaattgc
    88681 caaaatcaat cgtaaaaagt ctgcaactgg ctgaagacaa tatcgaatcg gctgaattga
    88741 tggataagat gatcaatctc caagttattc caggaaatac ggcttttgta aaagctcagt
    88801 taatcgagac ttttgcagac aagattttta gctgtttgac tgatgatagc tcgattttag
    88861 tcattgccag aagtggaagt ctagcagagg aaatctttga acaagtaaaa aattggtagg
    88921 tctatatgtt acttgaaatt tcgataaaaa actttgccat tattgaggct atttccctca
    88981 attttgaaaa ggggatgact gtcctgactg gtgaaacggg tgcagggaag tcgattatca
    89041 ttgatgccat gaatatgatg ttgggagctc gtgcgacgac agatgttatt cgtcatggtg
    89101 caccaaaggc agagattgag gggcttttct cagttgagaa tagtcgtctt ttacaggaaa
    89161 tttttgatga gcaaggttta gaattaggtg atgaaattat catccgtcgg gaaatcttgc
    89221 aaaatggtcg tagtatcagc cgtgtaaatg gtcagatggt taatctgtct gttttgcgaa
    89281 ctattgggca acatcttgta gatattcatg gtcagcatga ccatgaggag ttaatgcgtc
    89341 cccaactgca tatccagatg ttggatgaat ttggtgatgc cgctttttgg gacttgaaag
    89401 aaacctatca aacgagtttt gatgcctatc ggaaaatgcg caagcaggtt ctggaagtca
    89461 agaaaaacca acaggaacac aaggcacgta tcgaaatgtt ggaatttcaa atggcagaga
    89521 ttgaggcagc aaacttgcag gctggagaag acttggatct caatcaagag cgagataaac
    89581 tcctcaacca caaaaatatt gcggatacac tgaccaatgc ctacagtatg ttggacaatg
    89641 aagatttttc aagtctggcc aatgttcgtt cagccatgaa tgacatggaa agtgtcgaag
    89701 agtatgaccc tgaataccgt gaaatttcaa gctctctgtc tgagacctac tatgttttag
    89761 aagacattag caaacgtttg gaagctatca ttgaggacct tgattttgat ggcaatcgcc
    89821 tcatgcaggt tgagaatcgt ttggacctcc ttcatactat tactcgtaag tatggtggga
    89881 ctgttgatga tgttttgctt tattttgcca agattacgga agaatacaat ctcttgacag
    89941 gcaataatct ttcgtctgag gacatggaag cagagcttaa gaagttggaa gtcaatcttg
    90001 tcaatttggc aggtcaactt gcttctgctc gtcataattt ggctcagcaa ctcgaagctg
    90061 agattaaaca agaactgcaa gatctttata tggaaaaagc ccagtttcag gttcgtttta
    90121 gtaagggaaa attcagtcgt gagggaaata aaatggttga gttttatatt tcaaccaacc
    90181 ctggagaaga ctttaaaccc ttggttaagg ttgcttctgg aggggaatta tctcgtctca
    90241 tgttagccat taagtctgcc ttttcacgta aagaaggcaa gactagcatt gtctttgatg
    90301 aggtggatac gggagtttca ggtcgtgttg ctcaagctat tgctcagaaa attcataaaa
    90361 ttggtcagca tggtcaggtt ttggctatct cccatttgcc acaagtaatt gcgattgcag
    90421 attatcaatt ctttattgag aagattagta atgaccattc aacggtttcg actgttcgtc
    90481 tcttgacggt cgaagagcga gtggaggaag ttgccaagat gttggcaggt gatgatgtga
    90541 cagaagcagc cctgacgcaa gcaagagaat tgttgagaaa cagggagaaa taagatgaca
    90601 gattattatg taattggaga tgttcacgga aaagctggga tgctggaaga ccttctcaaa
    90661 acctgggatg gtcagcccca gttgctcttt ctaggtgatt tgattgacag aggtgaggat
    90721 agtcaccgtg ttcttgaaat ggtcaaggac ttggtggaca atcaaggggc tatctgtttg
    90781 tccggaaacc acgagtatat gtttttgact tggctagatg acccagaaga aagttatgac
    90841 cattatagtc gcaatggtgg agatacaacc attaactcta tcctaggtcg tcccttggat
    90901 gcaccagttg atggagtaga agatgccaag cgggttgccg ctgaagcggc agacttggtc
    90961 gaattcattc gtcaaatgcc atttgtagta gagacagaca agtatatctt tgttcacgca
    91021 ggtattgatt tgaccttgga cgactggcat gaaacaacag attataaaaa agtatggctt
    91081 agaaaaccat tccacggagc tgaaaatcat actggaaaaa ccattgtctt cggtcataca
    91141 ccggtctatg gtttattaca gcaagaacgc ggtacatctg agctttggac tacagaagat
    91201 ggcaagattg gaatggatgg aggagctgtt tatggtggtg tccttcacgg gattgtcttt
    91261 acagaccaag gaatgacaga acaccacttt atcgaaaatg acggctttgt cgctgaagat
    91321 tagtactcct agcagggtat ggtcttgtca aaatatcaaa aacaatttat aataaataga
    91381 taccctgaaa ggaagagaat catgaactta gaagaattga aaaaacgaca ggagaagatc
    91441 cgtaacttct ctattatcgc ccatattgac cacggaaaat caactctagc agaccgcatt
    91501 ttggaaaaaa cagagacggt ttcaagtcgt gaaatgcagg cccagctttt ggatagcatg
    91561 gagctagagc gggaacgtgg aattactatt aagttgaatg ccatcgagtt gaattacact
    91621 gcaaaagatg gggaaactta tattttccac ttgattgaca caccagggca cgttgacttt
    91681 acctatgaag tttcacgttc gctagctgcc tgtgagggtg ctattttggt ggtcgatgcg
    91741 gctcaaggaa ttgaggctca aactcttgcc aacgtttatc tggctttgga taatgatttg
    91801 gaaatcatgc ctatcattaa taaaattgac ctgccggctg cagatccgga gcgcgtgcgt
    91861 acagagattg aagatgtgat tggtttggat gccagtgaag cagttttggc ttctgccaag
    91921 gctggtattg ggattgaaga aatcctcgag caaattgtag aaaaagtacc agcaccaacg
    91981 ggtgatgtga cggcgccact taaggccttg attttcgact ctgtttacga tgcttaccgt
    92041 ggggttatcc tccaagtgcg tgtcatggac ggagtggtca aacctggtga taagattcag
    92101 ctcatgagca atagtaagac ctttgatgtg gccgaagtcg gtatttttac accaaaagcg
    92161 gttggtcgtg atttccttgc gactggtgat gttggttaca ttgcggcgtc tatcaagacg
    92221 gttcaggata ctcgtgtggg tgataccgtt accttggcaa ccaatcctgc ggcagaacca
    92281 ttacatggtt ataagcagat gaatcctatg gtctttgcgg gtctctaccc aatcgaatca
    92341 aacaagtaca atgacctgcg tgaagcgctt gaaaaattgc aactgaatga tgctagtctt
    92401 cagtttgaac cagaaacatc tcaggcactt ggatttggtt tccgttgtgg atttcttgga
    92461 cttctccata tggatgttat ccaggaacgt ttagagcgtg agttcaatat tgacctcatc
    92521 atgacagctc cgtctgttat ttacaaagtt aatttgaccg acggtgagtc tatggatgtg
    92581 tctaacccat ctgagtttcc agacccaact aagattgcga ccattgaaga gccttatgtc
    92641 aaggcgcaaa tcatggtacc acaggagttc gtcggagcag taatggagct agctcagcgt
    92701 aagcgtgggg actttgtgac tatggactat attgatgata accgtgtcaa tgttatctat
    92761 caaattcctc ttgctgaaat tgtctttgac ttctttgata aacttaagtc ttcgacacgt
    92821 ggttatgcaa gctttgacta cgaattgtca gaatatcgcc catctaagct ggtgaaaatg
    92881 gatattcttc tcaatggaga taaggtggat gccctcagct ttatcgttca caaggacttt
    92941 gcctacgaac gtgggaaact catcgttgat aaactcaaga aaatcatccc tcgccaacaa
    93001 tttgaagttc caatccaagc ggctattgga cacaagattg tcgctcgtac tgatatcaag
    93061 gcccttcgta agaacgtact tgctaaatgt tatggtggtg acgtttctcg taagcgtaaa
    93121 ctccttgaaa aacaaaaagc tggtaagaaa cgcatgaaat ccatcggatc agttgaagtt
    93181 ccgcaagaag ccttcctcag cgtcttgagt atggatgaag aataagttat cagaaatgcc
    93241 tttccttgtt cacaggaaat ttataagaat caatagtaaa gcaggcttag atggtctgct
    93301 tttttagttt ttatactctt cgaaaatctc ttcaaaccac gtcagcgtcg ccttaccgta
    93361 tgtatggtta ctgacttcgt cagtttcatc tacaacctca aaaccatgtt ttgagctgac
    93421 ttcgtcagtt tcatctacaa cctcaaaact gtgttttgaa caacctgcgg ctagcttcct
    93481 agtttgctct ttgattttca ttgagtatta gaacagaaaa aatgcttgga gtatttgttt
    93541 gtgtgtttac ttttatataa caaactataa acacaacaaa aatataaaaa aagagacaaa
    93601 aaagaacaga aagtaattaa caacgatttc atatagtgtt atacttatag cataaagtta
    93661 atggaaagaa gggaaaacct tatggtatta gattatttct ttgacaaaaa ccttgtgttt
    93721 tgcttagaag cggataatca agaataactc tttgatcagg tagcaagctt gttggaggaa
    93781 cgagaaattg taactccaac ttatcgtgaa gccttgatca cgcgtgaaaa gtcatttcca
    93841 actggtttag atatggaatt tctaggaaag gacttgccaa atgtagcgat tcctcataca
    93901 gatattgttc ataatctagc tgagaaagtg gtggttgttc gattagaaaa accagtaact
    93961 tttcacaata tgatagctcc tgataaggaa g
//
LOCUS       DAVBDR010000002        83333 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.002, whole genome shotgun sequence.
ACCESSION   DAVBDR010000002 DAVBDR010000000
VERSION     DAVBDR010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 83333)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 83333)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..83333
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.002"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            <1..160
                     /locus_tag="VQ540_000099"
     CDS             <1..160
                     /locus_tag="VQ540_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
                     /protein_id="HET2543980.1"
                     /translation="NHALSKERSKVENIFAKVKTFKMFSTTYRNHRKRFGLRMNLIAG
                     IINHELGF"
     gene            228..476
                     /locus_tag="VQ540_000100"
     CDS             228..476
                     /locus_tag="VQ540_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2543981.1"
                     /translation="MVSSSGSEFQSGWQEHQLIAEKVSKTLDKTFDKDVREIPTSQFY
                     QKFVDEMGRIYSGNLILQELITVNGAYKATYIGELSSN"
     gene            607..1779
                     /locus_tag="VQ540_000101"
     CDS             607..1779
                     /locus_tag="VQ540_000101"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004181031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HET2543982.1"
                     /translation="MTIGIDKIGFATSQYVLKLQDLAEARGIDPEKLSKGLLLKELSI
                     APLTEDIVTLAASASDSILTEQERQEVDMVIVATESGIDQSKAAAVFVHGLLGIQPFA
                     RSFEIKEACYGATAALHYAKLHVENSPESKVLVIASDIAKYGIETPGEPTQGAGSVAM
                     LITQNPRMMAFNNDNVAQTRDIMDFWRPNYSTTPYVNGVYSTQQYLDSLKTTWLEYQK
                     RYQLTLDDFAAVCFHLPYPKLALKGLKKIMDKSLPQEKKDLLQKHFDQSILYSQKVGN
                     IYTGSLFLGLLSLLENADSLKAGDKIALYSYGSGAVAEFFSGELVEGYEAYLDKDRLN
                     KLNQRTALSVADYEKVFFEEVNLDETNSAQFAGYENQDFALVEILDHQRRYSKVEK"
     gene            1779..3053
                     /locus_tag="VQ540_000102"
     CDS             1779..3053
                     /locus_tag="VQ540_000102"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000704367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HET2543983.1"
                     /translation="MKISWNGFSKKSYQERLELLKAQALLSPERQASLEKDEQMSVTV
                     ADQLSENVVGTFSLPYSLVPEVLVNGQEYTVPYVTEEPSVVAAASYASKIIKRAGGFT
                     AQVHQRQMIGQVALYQVANPKLAQEKIASKKAELLEFANQAYPSIVKRGGGARDLHVE
                     QIKGEPDFLVVYIHVDTQEAMGANMLNTMLEALKPVLEELSQGQSLIGILSNYATDSL
                     VTASCRMAFRYLSRQKDQGREIAEKIALASQFAQADPYRAATHNKGIFNGIDAILIAT
                     GNDWRAIEAGAHAFASRDGRYQGLSCWTLDLEREELVGEMTLPMPVATKGGSIGLNPR
                     VAFSHDLLGNPSARELAQIIVSIGLAQNFAALKALVSTGIQQGHMKLQAKSLALLAGA
                     SESEVAPLVERLISDKTFNLETAQRYLENLRS"
     gene            complement(3089..4054)
                     /locus_tag="VQ540_000103"
     CDS             complement(3089..4054)
                     /locus_tag="VQ540_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002929307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HET2543984.1"
                     /translation="MVAKLTDVAKLAGVSPTTVSRVINKKGYLSEKTIQKVNEAMREL
                     GYKPNNLARSLQGKSAKLIGLIFPNISNVFYAELIDKLEHQLFKNGYKTIICNSEHDS
                     EKEREYIEMLEANQVDGIISGSHNLGIEDYNRVTAPIISFDRNLSPDIPVVSSDNYAG
                     GVLAAQTLVKTGAQTIIMITGNDNSNSPTGLRHAGFASVLPKAPIINVSSDFSPVRKE
                     MEIKNILTREKPDAIFASDDLTAILVIKIAQELGISVPKELKVIGYDGTYFIENYYPQ
                     LATIKQPLEEIACLTIDLLLQKIEGKEVATTGYFLPVTLLPGKSI"
     gene            complement(4035..5489)
                     /locus_tag="VQ540_000104"
     CDS             complement(4035..5489)
                     /locus_tag="VQ540_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HET2543985.1"
                     /translation="MEWTTERRYRLYQDWTQEEIQHIKENMAQSPWHTHYHVEPKTGL
                     LNDPNGFSYFDGKWILFYQNFPFGAAHGLKSWAQLESDDLVHFKETGIKVLPDTPLDS
                     HGAYSGSAMQFGDNLFLFYTGNVRDENWIRHPYQIGALMDKEGKITKIDKILIDQPAD
                     STDHFRDPQIFNFKSQYYAVVGGQDLEKKGFVRLYKAVNNDYTNWQAVGDLDFANDRT
                     AYMMECPNLVFVEEHPVLLYCPQGLDKKVLDYDNIFPNMYKIGASFDPKNAKMVDVSQ
                     LQNMDYGFEAYATQAFNAPDGRALAVSWLGLPDVSYPSDRFDHQGTFSLVKELTIKDD
                     KLYQYPVAAIKDLRASEEAFSNRSQTKNTYELELNLEANSQSEIVLLADKEGKGLSIN
                     FDLVNGQVTVDRSQAGEQYAQEFGTTRSCPIENQATTATIFIDNSVFEIFINKGEKVF
                     SGRVFPHADQNGILIKSGNPTGTYYELDYGRKTN"
     gene            5866..7749
                     /locus_tag="VQ540_000105"
     CDS             5866..7749
                     /locus_tag="VQ540_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HET2543986.1"
                     /translation="MNNQEIAKKVIDALGGRENVNSVAHCATRLRVMVKDEEKINKEV
                     IENLEKVQGAFFNSGQYQIIFGTGTVNKMYDEVVVLGLPTSSKDDMKAEVAKQGNWFQ
                     RAIRTFGDVFVPIIPVIVATGLFMGVRGLFNALEMPLPGDFATYTQILTDTAFIILPG
                     LVVWSTFRVFGGNPAVGIVLGMMLVSGSLPNAWAVAQGGEVTAMNFFGFIPVVGLQGS
                     VLPAFIIGVVGAKFEKAVRKVVPDVIDLLVTPFVTLLVMSILGLFVIGPVFHVVENYI
                     LIATKAILSMPFGLGGFLIGGVHQLIVVSGVHHIFNLLEVQLLAADHANPFNAIITAA
                     MTAQGAATVAVGVKTKNPKLKTLAFPAALSAFLGITEPAIFGVNLRFRKPFFLSLIAG
                     AIGGGLASILGLAGTGNGITIIPGTMLYVGNGQLPQYLLMVAVSFALGFALTYMFGYE
                     DEVDATAAAKQAEVAEEKEEVAPAALQNETLVTPIVGDVVALADVNDPVFSSGAMGQG
                     IAVKPSQGVVYALADAEVSIAFPTGHAFGLKTRNGAEVLIHVGIDTVSMNGDGFEAKV
                     AQGNKVKAGDVLGTFDSNKIAAAGLDDTTMVIVTNTADYASVAPVATGSVSKGDAVIE
                     VKI"
     gene            7898..8785
                     /locus_tag="VQ540_000106"
     CDS             7898..8785
                     /locus_tag="VQ540_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000164317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HET2543987.1"
                     /translation="MTKLYGSLEAGGTKFVCAVGDENFNVVEKTQFPTTTPIETIDKT
                     IEFFSKFDNLAGLAVGSFGPIDIDKNSKTYGFITTTPKPNWANVDLLGALRRALNVPM
                     YFTTDVNSSAYGEMVARNNAGGRIENLVYYTIGTGIGAGVIQRGEFIGGVGHPEMGHY
                     YVARHPMDIEKEFKGVCPFHKGCLEGYAAGTSLEARTGVRGETIELNNPVWDVQAYYI
                     AQAAVNATVTFRPDVIVFGGGVMAQQHMLDRVREKFTSLLNGYLPVPDVRDYIVTPAV
                     AGNGSATLGNFVLAKEVSK"
     gene            complement(9105..9722)
                     /locus_tag="VQ540_000107"
     CDS             complement(9105..9722)
                     /locus_tag="VQ540_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HET2543988.1"
                     /translation="MSQDKQMKAVSPLLQRVINISSIVGGVGSLIFCIWAYQAGILQS
                     KETLSAFIQQAGIWGPPLFIFLQILQTVVPIIPGALTSVAGVFIYGHIIGTIYNYIGI
                     VIGCAIIFYLVRLYGAAFVQSVVSKRTYDKYIGWLDKGNRFDRFFIFMMIWPISPADF
                     LCMLAALTKMSFKRYMTIIILTKPFTLVVYTYGLTYIIDFFWQML"
     gene            complement(10137..10325)
                     /locus_tag="VQ540_000108"
                     /pseudo
     CDS             complement(10137..10325)
                     /locus_tag="VQ540_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153868.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(10835..10915)
                     /locus_tag="VQ540_000109"
                     /pseudo
     CDS             complement(10835..10915)
                     /locus_tag="VQ540_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            11031..11924
                     /locus_tag="VQ540_000110"
     CDS             11031..11924
                     /locus_tag="VQ540_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2543989.1"
                     /translation="MLEVRSLEKSFGSKQVLFGIDFQARPGRILGLVGKNGAGKTTIF
                     HSILKFLEYQGEIGLDGQDIRQETYARIGYLPEERSLMPKLTVLEQVRYLATLKGMDA
                     KEVKEKLPQWMKRLEVKGKLTDKIKSLSKGNQQKIQLIITLIHEPDLIILDEPFSGLD
                     PVNTELLKQVIFQEKERGATIIFSDHVMTNVEELCDDILMIRDGRVVLHGPVQDVRNQ
                     YGKTRLFVSSERSKEELENLPHVKQVSLTKQGSWKLILEDESAGRELFPILTQGQYIA
                     TFDQQAPTIDEIFKLESGVEV"
     gene            11921..13120
                     /locus_tag="VQ540_000111"
     CDS             11921..13120
                     /locus_tag="VQ540_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2543990.1"
                     /translation="MRNMWVVIKETYLRHVESWSFFFMVISPFLFLGISVGIGHLQGS
                     SMAKNNKVAVVTTVPSVAEGLKNVNGVNFDYKDEASAKEAIKEEKLKGYLTIDQEDSV
                     LKAVYHGETSLENGIKFEVTGTLNELQNQLNRSTASLSQEQEKRLEQTIQFTEKIDEA
                     KENKKFIQTIAAGALGFFLYMILITYAGVTAQEVASEKGTKIMEVVFSSIRASHYFYA
                     RMMALFLVILTHIGIYVVGGLAAVLLFKDLPFLAQSGILDHLGDAISLNTLLFILISL
                     FMYVVLAAFLGSMVSRPEDSGKALSPLMILIMGGFFGVTALGAAGDNLLLKIGSYIPF
                     ISTFFMPFRTINGYAGGAEAWISLAITVIFAVVATGFIGRMYASLVLQTDDLGIWKTF
                     KRALSYK"
     gene            complement(13473..14240)
                     /locus_tag="VQ540_000112"
     CDS             complement(13473..14240)
                     /locus_tag="VQ540_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000498762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2543991.1"
                     /translation="MFWNLVHYEFKNVNKWYLALYAAVLVLSALIGIQTQGFKNLPYQ
                     ESQATMLLFLATVFGGLMLTLAISTIFLIIKRFKGSVYDRQGYLTLTLPVSEHHIITA
                     KLIGAFIWSLISTAVLALSAVIILALTAPEWIPLSYVITFVETHLPQIFLTGISFLLN
                     TISGILCIYLAISIGQLFNEYRTALAVAAYIGIQIVIGFIELFFNLSSNFYVNSLVGL
                     NDHFYMGAGIAIVKELIFIAIFYLGTYYILRNKVNLL"
     gene            complement(14257..14952)
                     /locus_tag="VQ540_000113"
     CDS             complement(14257..14952)
                     /locus_tag="VQ540_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2543992.1"
                     /translation="MSLLVFENVSKSYGATPALENVSLDIPAGKIVGLLGPNGSGKTT
                     LIKLINGLLQPDQGRVLINDMDPSPATKAVVAYLPDTTYLNEQMKVKEALTYFKTFYK
                     DFNLERAHHLLADLGIDENSRLKKLSKGNKEKVQLILVMSRDARLYVLDEPIGGVDPA
                     ARAYILNTIINNYSPTSTVLISTHLISDIEPILDEIVFLKDGKVVRQGNVDDIRYESG
                     ESIDQLFRQEFKA"
     gene            complement(14957..15322)
                     /locus_tag="VQ540_000114"
     CDS             complement(14957..15322)
                     /locus_tag="VQ540_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HET2543993.1"
                     /translation="MSWTFDNKKPIYLQIMEKIKLQIVSHTLEPNQQLPTVRELASEA
                     GVNPNTIQRALSDLEREGFVYSKRTTGRFVTKDKELIAQSRKQLSEEELEHFVSSMIH
                     FGYEKEELPGVVSDYIKGV"
     gene            15462..15935
                     /gene="nrdR"
                     /locus_tag="VQ540_000115"
     CDS             15462..15935
                     /gene="nrdR"
                     /locus_tag="VQ540_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001203675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HET2543994.1"
                     /translation="MRCPKCGATKSSVIDSRQAEEGNTIRRRRECDECQHRFTTYERV
                     EERTLVVVKKDGTREQFSRDKIFNGIIRSAQKRPVSSDEINMVVNRIEQKLRGRNENE
                     IQSEDIGSLVMEELAELDEITYVRFASVYRSFKDVSELESLLQQITQSSKKKKER"
     gene            15936..17105
                     /locus_tag="VQ540_000116"
     CDS             15936..17105
                     /locus_tag="VQ540_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000802368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation and membrane attachment
                     family protein"
                     /protein_id="HET2543995.1"
                     /translation="MKPIDRFSYLKNNRVSQDTSSLVQCYLPIIGQEALSLYLYTISF
                     WDNGRKEYLFSSILNHLNFGMDRLIKSLKILSAFNLLTLYQKGDVYQLALHAPLSSQD
                     FLEHPVYRRLLEKKIGDSAVEDLKVESADGEEIPVSLNQVFPELAELGSQEDLGLKKK
                     VANDFDLEHFRQLMARDGLRFADEQSDVLNLFAIAEEKKWTWFETYQLAKSTAVSQVI
                     STKRMREKIAQKPVSSDFNPKEATIIKEAKSKTALQFLAEIKQTRKGTITQTERELLQ
                     QMAGLGLLDEVINIILLLTFNKVDSANINEKYAMKVANDYAYQKIHSAEEAVLRIRER
                     GQKTKTQKQNQTAPAKTNIPKWSNPDYKNETSEETRLELERKKQELLARLEKGGD"
     gene            17106..18002
                     /gene="dnaI"
                     /locus_tag="VQ540_000117"
     CDS             17106..18002
                     /gene="dnaI"
                     /locus_tag="VQ540_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HET2543996.1"
                     /translation="MESVGDVLKRQPSRFYYQDLVQKIMKDPDVAAFIQQESLTPEEL
                     NRSISKFNQYITERDKFLRGDTDYIAKGYKPILVKNHGYADVSYEETPELIAAEKEAA
                     IKNRLKLINLPASLKKASLAQVDLDDLGRLPVFEKLLAFVEQYPAIRKGLYLYGDFGV
                     GKSFMVAALAHDLSEKRGVSSTLLHYPSFVIDVKNAISDGNVKTLVDEIKLSEVLILD
                     DIGAEQSTAWVRDEILQVILQYRMQENLPTFFTSNFNFEDLEKHFAKVKHGNDETWEA
                     RRVMERIRYLAEETRLEGVNRR"
     gene            17999..18712
                     /locus_tag="VQ540_000118"
     CDS             17999..18712
                     /locus_tag="VQ540_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent oxidoreductase"
                     /protein_id="HET2543997.1"
                     /translation="MTETIKLMKAHTSVRRFKEQEIPQVDLNEILTAAQMASSWKNFQ
                     SYSVIVVRSQEKKDALYELVPQEAIRQSAVFLLFVGDLNRAEKGARLHTDTFQPQGVE
                     GLLISSVDAALAGQNALLAAESLGYGGVIIGLVRYKSEEVAELFNLPDYTYSVFGMAL
                     GVPNQHHDMKPRLPLENVVFEEEYQEQSTEAIQAYDRVQADYAGARATTSWSQRLAEQ
                     FGQAEPSSTRKNLEQKKLL"
     gene            18726..20036
                     /gene="der"
                     /locus_tag="VQ540_000119"
     CDS             18726..20036
                     /gene="der"
                     /locus_tag="VQ540_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HET2543998.1"
                     /translation="MALPTIAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYA
                     TGEWLNRSFSMIDTGGIDDVDAPFMEQIKHQAEIAMEEADVIVFVVSGKEGITDADEY
                     VARKLYKTHKPVILAVNKVDNPEMRNDIYDFYALGLGEPLPISSVHGIGTGDVLDAIV
                     ENLPNEYEEENPDVIKFSLIGRPNVGKSSLINAILGEDRVIASPVAGTTRDAIDTHFT
                     DTDGQEFTMIDTAGMRKSGKVYENTEKYSVMRAMRAIDRSDVVLMVINAEEGIREYDK
                     RIAGFAHEAGKGMIIVVNKWDTLEKDNHTMKNWEEDIREQFQYLPYAPIIFVSALTKQ
                     RLHKLPEMIKQISESQNTRIPSAVLNDVIMDAIAINPTPTDKGKRLKIFYATQVATKP
                     PTFVIFVNEEELMHFSYLRFLENQIRKAFVFEGTPIHLIARKRK"
     gene            20127..20462
                     /locus_tag="VQ540_000120"
     CDS             20127..20462
                     /locus_tag="VQ540_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2543999.1"
                     /translation="MEHLFKFLLLAPYFYFDNWIEKANRNSKFFPIFYYFYWFYIPFY
                     SLFSLAWTVVSVLFFNTVLRNVTDIKLWGIWFLFILLAIGMNWLTYSCFKEMFRLRQE
                     LGKSKGGRH"
     gene            20602..20937
                     /locus_tag="VQ540_000121"
     CDS             20602..20937
                     /locus_tag="VQ540_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2544000.1"
                     /translation="MEYLFKMIILLPCFYFFSWIEKANRDSKIFPIFYYFYWIYITLY
                     ALFSLAWTVFSVLFFNIVLRNLTDIKLWGIWLLLLLIAFASDWLDYICFKKMLDLRRE
                     LGKSKGGRH"
     gene            21122..21913
                     /locus_tag="VQ540_000122"
     CDS             21122..21913
                     /locus_tag="VQ540_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2544001.1"
                     /translation="MKIPLLTLARHKFVYVLLTLLFLALVYRDVLMTYFFFDIHAPDL
                     AKFDGQAIKNDLLKSALDFRILQFNLGFYQSFIIPIIIVLLGFQYIELKNKVLRLSIG
                     REVSYQGLKRKLTLQVASIPCLIYLVTVLIIAIITYFFGTFSPLEWNSLFSDGSGLQR
                     LLDGEIKSYLFFTCVLLIGIFINAIYFLQIVDYVGNVTRSAITYLMFLWLGSMLLYSA
                     LPYYMVPMTSLMQASYGDVSLMKLFTPYILYVVPYMVLKKYEDNV"
     gene            21906..22547
                     /locus_tag="VQ540_000123"
     CDS             21906..22547
                     /locus_tag="VQ540_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000475766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2544002.1"
                     /translation="MFKNFNNIWLKRKIVLLLRIVLMMILINYLLSTAVQKQDAVIFF
                     KRELISIFSYNDYSEANLEIPKLLLNLSLFMVGWLSVILLESDLADHYHHLIRYQSSS
                     FFDYTRKRLVVISKFFTQDLFVWFLGLLPLGIHFKTVALFFLLAQLMMLYLLLSYLIA
                     LISAGAGFSFFLYFLAFVGQEWMMDHIVTVYLVLLSLLVMLIVSRLEEKFKKG"
     gene            22551..23201
                     /locus_tag="VQ540_000124"
     CDS             22551..23201
                     /locus_tag="VQ540_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET2544003.1"
                     /translation="MRLEIINGQKIYGKRPILNQLNLVFQSGKIYGLKGDNGSGKTVL
                     LKILAGYIKLDKGKVLQDGKVYGVKNHYIQDAGILIEKVEFLSHLSLRENLELLRYFS
                     SKVTEKRIAYWIQYYDLQEFEDVEYRHLSLGTKQKMALIQAFISSPSILFLDEPMNAL
                     DEKSVRLTKQVILSYLKKENGLVILTSHISEDISDLCTDVLVVENGHIQYVKDIQS"
     gene            23212..23499
                     /locus_tag="VQ540_000125"
     CDS             23212..23499
                     /locus_tag="VQ540_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000940707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2544004.1"
                     /translation="MAHLKSFITRYSKVYIGLVLLIWLSFFFIPWDRAILGVRIDIFI
                     MQKILLAFGILSILMALLSKKVSLFVFGLICCLSLWINLFITFAILPIFGN"
     gene            23645..26158
                     /gene="secA"
                     /locus_tag="VQ540_000126"
     CDS             23645..26158
                     /gene="secA"
                     /locus_tag="VQ540_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HET2544005.1"
                     /translation="MANILKTIIENDKGEIRRLEKMADKVFKYEDQMATLTDDQLKAK
                     TVEFKERYQNGESLDSLLYEAFAVVREGAKRVLGLFPYKVQVMGGIVLHHGDVPEMRT
                     GEGKTLTATMPVYLNALSGKGVHVVTVNEYLSERDATEMGELYSWLGLSVGINLATKS
                     PMEKKEAYECDITYSTNSEIGFDYLRDNMVVRAENMVQRPLNYALVDEVDSILIDEAR
                     TPLIVSGANAVETSQLYHMADHYVKSLNKDDYIIDVQSKTIGLSDSGIDRAESYFKLE
                     NLYDIENVALTHFIDNALRANYIMLLDIDYVVSEEQEILIVDQFTGRTMEGRRYSDGL
                     HQAIEAKEGVPIQDETKTSASITYQNLFRMYKKLSGMTGTGKTEEEEFREIYNIRVIP
                     IPTNRPVQRIDHSDLLYASIESKFKAVVEDVKARYQKGQPVLVGTVAVETSDYISKKL
                     VAAGVPHEVLNAKNHYREAQIIMNAGQRGAVTIATNMAGRGTDIKLGEGVRELGGLCV
                     IGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDDLMKRFGSERLKGIFERLNMSE
                     EAIESRMLTRQVEAAQKRVEGNNYDTRKQVLQYDDVMREQREIIYAQRYDVITADRDL
                     APEIQAMIKRTIERVVDGHARAKQDEKLEAILNFAKYNLLPEDSITMEDLSGLSDKAI
                     KEELFQRALKVYDSQVSKLRDEEAVKEFQKVLILRVVDNKWTDHIDALDQLRNAVGLR
                     GYAQNNPVVEYQAEGFRMFNDMIGSIEFDVTRLMMKAQIHEQERPQAERHISTTATRN
                     IAAHQASMPEDLDLSQIGRNELCPCGSGKKFKNCHGKRQ"
     gene            26239..27270
                     /locus_tag="VQ540_000127"
     CDS             26239..27270
                     /locus_tag="VQ540_000127"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000232189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HET2544006.1"
                     /translation="MVFTAKSSKINIEEVRALSKLEGQALERKSQRDQELEAIIRGED
                     QRILLVIGPCSSDNEEAVLEYAKRLAVLQEEVADRIFMVMRVYTAKPRTNGDGYKGLI
                     HQPNATEAPSLINGIKAVRHLHYRVITETGMTTADEMLYPENLPLVDDLISYMAVGAR
                     SVEDQQHRFVASGAGFSTGFKNPTSGNLNVMFNGIYAAQNKQSFLFLGKEVETTGNPL
                     SHAILRGALNEYGKNIPNYYYDNLIDTIAQYEKMGLENPFIIIDTNHDNSGKQYIEQI
                     RIVRQTLINRAWNEKIKQFVRGFMIESYLEDGRQNEPEVFGKSITDPCLGWDNTEALV
                     REIYKTLGE"
     gene            27272..28303
                     /locus_tag="VQ540_000128"
     CDS             27272..28303
                     /locus_tag="VQ540_000128"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HET2544007.1"
                     /translation="MAFIEKGQEIDMEVIKAETQLSAEALRLKESRDRELADIISGED
                     DRILLVIGPCSSDNEEAVLEYARRLSALQKKVADKIFMVMRVYTAKPRTNGDGYKGLV
                     HQPDTSKAPSLINGLQAVRQLHYRVITETGLTTADEMLYPSNLILVDDLVSYHAVGAR
                     SVEDQEHRFVASGIDAPVGMKNPTSGNLGVMFNAIYAAQNKQTFLYHGQEVETSGNPL
                     AHVILRGAVNEYGNYMPNYYYENLLQAIERYETMGLENPFILIDTNHDNSGKQYMEQI
                     RIVRQTLQNRDWNEKIKKTVRGFMIESYLADGRQNQPEIFGCSITDPCLGWENTEALV
                     EEIYVTLTK"
     gene            28342..28710
                     /locus_tag="VQ540_000129"
     CDS             28342..28710
                     /locus_tag="VQ540_000129"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000061844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HET2544008.1"
                     /translation="MRMIVGHGIDIEELASIESAVTRHEGFAKRVLTAQEMERFTSLK
                     GRRQIEYLAGRWSAKEAFSKAMGTGISKLGFQDLEVLNNERGAPYFSQAPFSGKIWLS
                     ISHTDQFVTASVILEENHES"
     gene            28700..29803
                     /locus_tag="VQ540_000130"
     CDS             28700..29803
                     /locus_tag="VQ540_000130"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000648075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HET2544009.1"
                     /translation="MKASPHRPTKALIHLGAIRQNIQQMGAHIPQGTLKLAVVKANAY
                     GHGAVAVAKAIQDDVDGFCVSNIDEAIELRQAGLSKPILILGVSEIEAVALAKEYDFT
                     LTVAGLEWIQALLDKEVDLTGLTVHLKIDSGMGRIGFREASEVEQAQDLLQQHGVRVE
                     GIFTHFATADEESDDYFNAQLERFKTILASMKEVPELVHASNSATTLWHVETIFNAVR
                     MGDAMYGLNPSGAVLALPYDLIPALTLESALVHIKTVPAGACMGYGATYQTDSEQVIA
                     TVPIGYADGWTRDMQNFSVLVDGQACPIVGRVSMDQITIRLPKPYPLGTKVTLIGSNG
                     DKEITATQVATYRVTINYEVVCLLSDRIPREYY"
     gene            29822..31837
                     /gene="recG"
                     /locus_tag="VQ540_000131"
     CDS             29822..31837
                     /gene="recG"
                     /locus_tag="VQ540_000131"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HET2544010.1"
                     /translation="MNLHQPLHVLPGVGPKSAEKYAKLGIENLQDLLLYFPFRYEDFK
                     IKQVLELEDGEKAVLSGQVVTPASVQYYGFKRNRLRFSLKQGEVVFAVNFFNQPYLAD
                     KIELGATLAVFGKWDRAKASLTGMKVLAQVEDDLQPVYRLAQGISQASLVKVIKTAFD
                     QGLDLLIEENLPQSLLDKYKLMSRCQAVRAMHFPKDLAEYKQALRRIKFEELFYFQMQ
                     LQMLKSENRVQGSGLVLNWSQEKVTAVKVSLPFALTQAQEKSLQEILTDMKSDHHMNR
                     LLQGDVGSGKTVVAGLAMFAAVTAGYQAALMVPTEILAEQHFESLQNLFPNLKLALLT
                     GSLKAAEKREVLETIAKGEADLIIGTHALIQDGVEYARLGLIIIDEQHRFGVGQRRIL
                     REKGDNPDVLMMTATPIPRTLAITAFGDMDVSIIDQMPAGRKPIVTRWIKHEQLPQVL
                     TWLEGEIQKGSQAYVISPLIEESEALDLKNAIALSEELTTHFAGKAEVALLHGRMKSD
                     EKDQIMQDFKERKTDILVSTTVIEVGVNVPNATVMIIMDADRFGLSQLHQLRGRVGRG
                     DKQSYAVLVANPKTDSGKDRMRIMTETTNGFVLAEEDLKMRGSGEIFGTRQSGLPEFQ
                     VADIIEDFPILEEARKVASYISSIEAWQEDPEWRMIALHLEKKEHLD"
     gene            32153..33133
                     /locus_tag="VQ540_000132"
     CDS             32153..33133
                     /locus_tag="VQ540_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetylxylan esterase"
                     /protein_id="HET2544011.1"
                     /translation="MKNPALLEEIKTYRGRDEVPEDFDAFWDGEVKNVSTLPSYHLEE
                     RDFHIPQVKCYELTFEGSKEGKVYARIVLPKSEEKVPLIFHFHGYMGRGWDWADMLGF
                     TVAGYGVVSMDVRGQSGYSQDGLRSPLGNTVKGHIIRGAMEGRDHLFYKDVYLDIYQL
                     VEIVASLSQVDEKRLSSYGASQGGALALVAAALNPRIQKTVAIYPFLSDFRRVIEIGN
                     TSEAYDELFRYFKFHDPFHETEEEIMATLAYIDVKNLAHRIQGEVKMITGLDDDVCYP
                     ITQFAIYNRLTCDKTYRIMPEYAHEAMNVFVNDQVYNWLCGSEIPFKYLK"
     gene            33938..34165
                     /locus_tag="VQ540_000133"
     CDS             33938..34165
                     /locus_tag="VQ540_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2544012.1"
                     /translation="MIFKAFKTKKQRKRQVELLLTVFFDSFLIDLFLHLFGIVPFKLD
                     KILIVSLIIFPIISTSIYAYEKLFEKVFDKD"
     gene            34453..37350
                     /gene="nanA"
                     /locus_tag="VQ540_000134"
     CDS             34453..37350
                     /gene="nanA"
                     /locus_tag="VQ540_000134"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored neuraminidase NanA"
                     /protein_id="HET2544013.1"
                     /translation="MNRSVQERKCRYSIRKLSVGAVSMIVGAVVFGTSPVLAQEGASE
                     QPLANETQLSGESSTLTDTEKSQPSSETELSGNKQEQERKDKQEEKIPRDYYARDLEN
                     VETVIEKEDVETNASNGQRVDLSSELDKLKKLENATVHMEFKPDAKAPAFYNLFSVSS
                     ATKKDEYFTMAVYNNTATLEGRGSDGKQFYNNYNDAPLKVKPGQWNSVTFTVEKPTAE
                     LPNGRVRLYVNGVLSRTSLKSGNFIKDMPDVTHVQIGATKRANNTVWGSNLQIRNLTV
                     YNRALTPEEVQKRSQLFKRSDLEKKLPEGAALTEKTDIFESGRNGKPNKDGIKSYRIP
                     ALLKTDKGTLIAGADERRLHSSDWGDIGMVIRRSEDNGKTWGNRVTITNLRDNPKASD
                     PSIGSPVNIDMVLVQDPETKRIFSIYDMFPEGKGIFGMSSQKEEAYKKIDGKTYQILY
                     REGEKGAYTIRENGTVYTPDGKATDYRVVVDPVKPAYSDKGDLYKGNQLLGNIYFTTN
                     KTSPFRIAKDSYLWMSYSDDDGKTWSAPQDITPMVKADWMKFLGVGPGTGIVLRNGPH
                     KGRILIPVYTTNNVSHLNGSQSSRVIYSDDHGKTWHAGEAVNDNRQVDGQKIHSSTMN
                     NRRAQNTESTVVQLNNGDVKLFMRGLTGDLQVATSKDGGVTWEKDIKRYPQVKDVYVQ
                     MSAIHTMHNGKEYIILSNAGGPNRENGMVHLARVEENGELTWLKHNPIQKGEFAYNSL
                     QELGNGEYGILYEHTEKGQNAYTLSFRKFNWEFLSKDLISPTEAKVKRTREMGKGEMG
                     KGVIGLEFDSEVLVNKAPTLQLANGKTATFLTQYDSKTLLFAVDKEDIGQEIIGIAKG
                     SIESMHNLPVNLAGARVPGGVNGSKAAVHEVPEFTGGVNGTEPAVHEIAEYKGSDSLV
                     TLTTKEDYTYKAPLAQQALPETGNKESDLLASLGLTAFFLGLFTLGKKREQ"
     gene            38365..38817
                     /locus_tag="VQ540_000135"
     CDS             38365..38817
                     /locus_tag="VQ540_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HET2544014.1"
                     /translation="MIITKISHLGTYVGVNPHFATLIDFLEKTGLENLTEGSIAIDGN
                     RLFGNCFTYLADGQAGAFFETHQKYLDIHLVLENEEAMAVTSPENVSVTQEYDEEKDI
                     ELYTGKVEQLVQLRAGECLITFPEDLHQPKVRINDEPVKKVVFKVAIS"
     gene            38836..40173
                     /locus_tag="VQ540_000136"
     CDS             38836..40173
                     /locus_tag="VQ540_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HET2544015.1"
                     /translation="MKKMRKFLCLAGIALAAVALVACSGKKEATTSTEPPTELSGEIT
                     MWHSFTQGPRLESIQKSADAFMQKHPKTKIKIETFSWNDFYTKWTTGLANGNVPDIST
                     ALPNQVMEMVNSDALVPLNDSIKRIGQDKFNETALNEAKIGDDYYSVPLYSHAQVMWV
                     RTDLLKEHNIEVPKTWDQLYEASKKLKEAGVYGLSVPFGTNDLMATRFLNFYVRSGGG
                     SLLTKDLKADLTSQLAQDGIKYWVKLYKEISPQDSLNFNVLQQATLFYQGKTAFDFNS
                     GFHIGGINANSPQLIDSIDAYPIPKIKESDKDQGIETSNIPMVVWKNSKHPEVAKAFL
                     EALYNEEDYVKFLDSTPVGMLPTIKGISDSAAYKENETRKKFKHAEEVITEAVKKGTA
                     IGYENGPSVQAGMLTNQHIIEQMFQDIITNGTDPMKAAKEAEKQLNDLFEAVQ"
     gene            40252..41136
                     /locus_tag="VQ540_000137"
     CDS             40252..41136
                     /locus_tag="VQ540_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET2544016.1"
                     /translation="MVKERNLTRWIFVLPAMIIVGLLFVYPFFSSIFYSFTNKHLIMP
                     NYKFVGLANYKAVLSDPNFFNAFFNSIKWTVFSLVGQVLVGFVLALALHRVRHFKKLY
                     RTLLIVPWAFPTIVIAFSWQWILNGVYGYLPNLIVKLGLMEHTPAFLTDSTWAFLCLV
                     FINIWFGAPMIMVNVLSALQTVPEEQFEAAKIDGASSWQVFKFIVFPHIKVVVGLLVV
                     LRTVWIFNNFDIIYLITGGGPANATTTLPIFAYNLGWGTKLLGRASAVTVLLFIFLVA
                     ICFIYFAIISKWEKEGRK"
     gene            41136..41969
                     /locus_tag="VQ540_000138"
     CDS             41136..41969
                     /locus_tag="VQ540_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HET2544017.1"
                     /translation="MKKKSSIYLDILSHVLLVGATIVAIFPLVWIIISSVKGKGELTQ
                     YPTRFWPEQFTLDYFTHVINDLHFIDNIRNSLIIALATTLIAIIISAMAAYGIVRFFP
                     KLGAIMSRLLVITYIFPPILLAIPYSIAIAKVGLTNSLFGLMMVYLSFSVPYAVWLLV
                     GFFQTVPIGIEEAARIDGANKFVTFYKVVLPIVAPGIVATAIYTFINAWNEFLYALIL
                     INNTGKMTVAVALRSLNGSEILDWGDMMAASVIVVLPSIIFFSIIQNKIASGLSEGSV
                     K"
     gene            41987..44080
                     /gene="nanB"
                     /locus_tag="VQ540_000139"
     CDS             41987..44080
                     /gene="nanB"
                     /locus_tag="VQ540_000139"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="neuraminidase NanB"
                     /protein_id="HET2544018.1"
                     /translation="MNKRGLYSKLGISVVGISLLMGVPTLIHANELNYGQLSISPIFQ
                     GGSYQLNNKSIDISPLLLDKLSGESQTVVMKFKADEPNSLQALFGLSNSKAGFKNNYF
                     SIFMRDSGEIGVEIRDAQKGINYLFSRPASLWGKHKGQAVENTLVFVSDSKDKTYTMY
                     VNGIEVFSETVDTFLPISNINGIDKATLGAVNREGKEHYLAKRSIDEISLFNKAISDQ
                     EVSNIPLSNPFQLIFQSGDSTQANYFRIPTLYTLSSGRVLSSIDARYGGTHDSKSKIN
                     IATSYSDDNGKTWSEPIFAMKFNDYEEQLVYWPRDNKLKNSQISGSASFIDSSIVEDK
                     KSGKTILLADVMPAGIGNNNANKADSGFKEINGHYYLKLKKNGDNDFRYTVRENGVVY
                     DETTNKPTNYTINDKYEVLEGGKSLTVEQYSVDFDSGSLRERHNGKQVPMNVFYKDSL
                     FKVTPTNYIAMTTSQNREESWEQFKLLPPFLGEKHNGTYLCPGQGLALKSSNRLIFAT
                     YTSGELTYLISDDSGQTWKKSSASIPFKNATAEAQMVELRDGVIRTFFRTTTGKIAYM
                     TSRDSGETWSEVSYIDGIQQTSYGTQVSAIKYSQLIDGKEAVILSTPNSRSGRKGGQL
                     VVGLVNKEDDSIDWKYHYDIDLPSYGYAYSAITELPNHHIGVLFEKYDSWSRNELHLS
                     NVVQYIDLEINDLTK"
     gene            44092..45195
                     /locus_tag="VQ540_000140"
     CDS             44092..45195
                     /locus_tag="VQ540_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HET2544019.1"
                     /translation="MVKYGVVGAGYFGAELARYMQKNDGAEITLLYDPDNAEAIAEEL
                     GAKVASSLDELVSSDEVDCVIVATPNNLHKEPVIKAAQHGKNVFCEKPIALSYQDCRE
                     MVDACKENNVTFMAGHIMNFFNGVHHAKELINQGVIGDVLYCHTARNGWEEQQPSVSW
                     KKIREKSGGHLYHHIHELDCVQFLMGGMPETVTMTGGNVAHEGEHFGDEDDMIFVNME
                     FSNKRFALLEWGSAYRWGEHYVLIQGSKGAIRLDLFNCKGTLKLDGQESYFLIHESQE
                     EDDDRTRIYHSTEMDGAIAYGKPGKRTPLWLSSVIDKEMRYLHEIMEGAPVSEEFAKL
                     LTGEAALEAIATADACTQSMFEDRKVKLSEIVK"
     gene            45369..46067
                     /locus_tag="VQ540_000141"
     CDS             45369..46067
                     /locus_tag="VQ540_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HET2544020.1"
                     /translation="MPQISKEALIEQIKDGIIVSCQALPHEPLYTEAGGVIPLLVKAA
                     EQGGAVGIRANSVRDIKEIKEVTKLPIIGIIKRDYPPQEPFITATMKEVDELAELDIE
                     VIALDCTKRERYDGLEIQEFIRQVKEKYPNQLLMADTSIFEEGLAAVEAGIDFVGTTL
                     SGYTSYSPKVDGPDFELIKKLCDAGVDVIAEGKIHTPEQAKQILEYGVRGIVVGGAIT
                     RPKEITERFVASLK"
     gene            46086..47603
                     /locus_tag="VQ540_000142"
     CDS             46086..47603
                     /locus_tag="VQ540_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000477452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HET2544021.1"
                     /translation="MFKVLQKVGKAFMLPIAILPAAGLLLGIGGALSNPTTIATYPIL
                     DNSIFQSIFQVMSSAGEVVFSNLSLLLCVGLCIGLAKRDKGTAALAGVTGYLVMTATI
                     KALVKLFMAEGSAIDTGVIGALVVGIVAVYLHNRYNNIQLPSALGFFGGSRFVPIVTS
                     FSSILIGFVFFVIWPPFQQLLVSTGGYISQAGPIGTFLYGFLMRLSGAVGLHHIIYPM
                     FWYTELGGVETVAGQTVVGAQKIFFAQLADLAHSGLFTEGTRFFAGRFSTMMFGLPAA
                     CLAMYHSVPKNRRKKYAGLFLGVALTSFITGITEPIEFMFLFVSPVLYVVHAFLDGVS
                     FFIADVLNISIGNTFSGGVIDFTLFGILQGNAKTNWVLQIPFGLIWSVLYYIIFRWFI
                     TQFNVLTPGRGEEVDSKEISESADSTSNTADYLKQDSLQIIRALGGSNNIEDVDACVT
                     RLRVAVKEVNQVDKALLKQIGAVDVLEVKGGIQAIYGAKAILYKNSINEILGVDD"
     gene            47728..49056
                     /locus_tag="VQ540_000143"
     CDS             47728..49056
                     /locus_tag="VQ540_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HET2544022.1"
                     /translation="MKFRKLACTVLAGAAVLGLAACGNSGGSKDAAKSGGDGAKTEIT
                     WWAFPVFTQEKTGDGVGTYEKSIIEAFEKANPDIKVKLETIDFKSGPEKITTAIEAGT
                     APDVLFDAPGRIIQYGKNGKLAELNDLFTDEFVKDVNNENIVQASKAGDKAYMYPISS
                     APFYMAMNKKMLEDAGVANLVKEGWTTDDFEKVLKALKDKGYTPGSLFSSGQGGDQGT
                     RAFISNLYSGSVTDEKVSKYTTDDPKFVKGLEKATSWIKDNLINNGSQFDGGADIQNF
                     ANGQTSYTILWAPAQNGIQAKLLEASKVEVVEVPFPSDEGKPALEYLVNGFAVFNNKD
                     DKKVAASKKFIQFIADDKEWGPKDVVRTGAFPVRTSFGKLYEDKRMETISGWTQYYSP
                     YYNTIDGFAEMRTLWFPMLQSVSNGDEKPADALKAFTEKANETIKKAMKQ"
     gene            49308..50174
                     /locus_tag="VQ540_000144"
     CDS             49308..50174
                     /locus_tag="VQ540_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET2544023.1"
                     /translation="MRETVISYAFLAPVLFFFVIFVLAPMVMGFITSFFNYSMTKFEF
                     VGLDNYIRMFKDPVFTKSLINTVILVIGSVPVVVLFSLFVASQTYHQNVIARSFYRFV
                     FFLPVVTGSVAVTVVWKWIYDPLSGILNFVLKSSHIISQNISWLGDKNWALMAIMIIL
                     LTTSVGQPIILYIAAMGNIDNSLVEAARVDGATEFQVFWKIKWPSLLPTTLYIAIITT
                     INSFQCFALIQLLTSGGPNYSTSTLMYYLYEKAFQLTEYGYANTIGVFLAVMIAIVSF
                     VQFKVLGNDVEY"
     gene            50190..51029
                     /locus_tag="VQ540_000145"
     CDS             50190..51029
                     /locus_tag="VQ540_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HET2544024.1"
                     /translation="MQSTEKKPLTAFTVISTIILLLLTVLFIFPFYWILTGAFKSQPD
                     TIVIPPQWFPKMPTMENFQQLMVQNPALQWMWNSVFISLVTMFLVCATSSLAGYVLAK
                     KRFYGQRILFAIFIAAMALPKQVVLVPLVRIVNFMGIHDTLWAVILPLIGWPFGVFLM
                     KQFSENIPTELLESAKIDGCGEIRTFWSVAFPIVKPGFAALAIFTFINTWNDYFMQLV
                     MLTSRNNLTISLGVATMQAEMATNYGLIMAGAALAAVPIVTVFLVFQKSFTQGITMGA
                     VKG"
     gene            51302..51754
                     /locus_tag="VQ540_000146"
     CDS             51302..51754
                     /locus_tag="VQ540_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HET2544025.1"
                     /translation="MIFDDLKNITFYKGIHPNLDKAIDYLYQHRKDSFELGKYEIDGD
                     KVFLVVQENVLNQVENNQFEHHKNYADLHLLIEGHEYSSYGSRIKDEAVAFDEATDIG
                     FVHCHEHYPLLLGYHNFAIFFPGEPHQPTGYAGMEEKVRKYLFKILID"
     gene            51851..52195
                     /locus_tag="VQ540_000147"
     CDS             51851..52195
                     /locus_tag="VQ540_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2544026.1"
                     /translation="MVSSKHAARASFLDGQEITVDEMSWIINGIVNALIGRYIKLGTY
                     AAKYGIGIARSILSRAAATAAARVGLLTKISGWILRVAVNVADVYGNFANNIAAAWDA
                     YDKIPNNGRINF"
     gene            52479..53123
                     /locus_tag="VQ540_000148"
     CDS             52479..53123
                     /locus_tag="VQ540_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000057467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HET2544027.1"
                     /translation="MAQKGVSLIKAAFDTDNFLMRFSEKVLDIVTANLLFVVSCLPIV
                     TIGVAKISLYETMFEVKKSRRVPVFKIYLRSFKQNLKLGLQLGLMELGIVFLTLSDLY
                     LFWGQTALPFQLLKAICLGILIFLTIVMLASYPIAARYDLSWKEILQKGLMLASFNFP
                     WFFLMLAILVLIVMVLYLSAFSLLLGGSVFLLFGFGLLVFIQTGLMEKIFAKYQ"
     gene            53292..54209
                     /locus_tag="VQ540_000149"
     CDS             53292..54209
                     /locus_tag="VQ540_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HET2544028.1"
                     /translation="MSDLKKYEGVIPAFYACYDEQGEVSPERTRALVQYFIDKGVQGL
                     YVNGSSGECIYQSVEDRKLILEEVMAVAKGKLTIIAHVACNNTKDSMELARHAESLGV
                     DAIATIPPIYFRLPEYSVAKYWNDISSAAPNTDYVIYNIPQLAGVALTPSLYTEMLKN
                     PRVIGVKNSSMPVQDIQTFVSLGGEDHIVFNGPDEQFLGGRLMGAKAGIGGTYGAMPE
                     LFLKLNQLIADKDLETARELQYAINAIIGKLTATHGNMYGVIKEVLKINEGLNIGSVR
                     SPLTPVTEEDRPVVEAAAALIRETKESFL"
     gene            54227..55111
                     /locus_tag="VQ540_000150"
     CDS             54227..55111
                     /locus_tag="VQ540_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HET2544029.1"
                     /translation="MTYYVAIDIGGTNIKYGLVDQEGQLLESHEMPTEAHKGGPHILQ
                     KTKDIVASYLEKGPVAGVAISSAGMVDPDKGEIFYAGPQIPNYAGTQFKKEIEESFTI
                     PCEIENDVNCAGLAEAVSGSGKGASVTLCLTIGTGIGGCLIMDRKVFHGFSNSACEVG
                     YMHMQDGAFQDLASTTALVKYVAEAHGEDVDQWNGRRIFKEATEGNKICMEGIDRMVD
                     YLGKGLANICYVANPEVVILGGGIMGQEAILKPKIRTALKEALVPSLAEKTRLEFAHH
                     QNTAGMLGAYYHFKTKQS"
     gene            complement(55127..55978)
                     /locus_tag="VQ540_000151"
     CDS             complement(55127..55978)
                     /locus_tag="VQ540_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HET2544030.1"
                     /translation="MDKPDIATIIDSHFEEMTDLEQEIARYFLQAETITDDLSSQQVT
                     QKLHISQAALTRFAKKCGFTGYREFIFQYQHQAENQANRVSKHSPLTKRVLRSYSNMR
                     EQTQDLIDEIQLERIAQLIEDAERIYFFGTGSSGLVAREMKLRFMRLGVVCEALTDQD
                     GFAWTTSIMDENCLVLGFSLSGSTPSILDSLLDAKEMGAKTVLFTSVPNKDSQTYTET
                     VLVATHSQPSYIQRISAQLPMLFFIDLIYAYFLEINRESKEKIFNSYWENKKLNGYRR
                     QKRVRKS"
     gene            56178..58235
                     /gene="pbp2b"
                     /locus_tag="VQ540_000152"
     CDS             56178..58235
                     /gene="pbp2b"
                     /locus_tag="VQ540_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2B"
                     /protein_id="HET2544031.1"
                     /translation="MRLICMRKFNSHSIPIRLNLLFSIVILLFMTIIGRLLYMQVLNK
                     DFYEKKLASASQTKITSSSARGEIYDASGKPLVENTLKQVVSFTRSNKMTATDLKETA
                     KKLLTYVSISSPNLTKRQLADYYLADPEIYKKTVEALPSEKRLDSDGNRLSESELYNN
                     AVDSVQTSQLNYTEDEKKEIYLFSQLNAVGNFATGTIATDPLNDSQVAVIASISKEMP
                     GISISTSWDRKVLETSLSSIVGSVSSEKAGLPAEEAEAYLKKGYSLNDRVGTSYLEKQ
                     YEETLQGKRSVKEIHLDKYGNMESVDTIEEGSKGNNIKLTIDLAFQDSVDALLKSYFN
                     SELENGGAKYSEGVYAVALNPKTGAVLSMSGIKHDLKTGELTPDSLGTVTNVFVPGSV
                     VKAATISSGWENGVLSGNQTLTDQSIVFQGSAPINSWYTQAYGSFPITAVQALEYSSN
                     TYMVQTALGLMGQTYQPNMFVGTSNLESAMEKLRSTFGEYGLGTATGIDLPDESTGFV
                     PKEYSFANYITNAFGQFDNYTPMQLAQYVATIANNGVRVAPRIVEGIYGNNDKGGLGD
                     LIQQLQPTEINKVNISDSDMSILHQGFYQVAHGTSGLTTGRAFSNGALVSISGKTGTA
                     ESYVADGQQATNTNAVAYAPSDNPQIAVAVVFPHNTNLTNGVGPSIARDIINLYQKYH
                     PMN"
     gene            58246..58842
                     /gene="recR"
                     /locus_tag="VQ540_000153"
     CDS             58246..58842
                     /gene="recR"
                     /locus_tag="VQ540_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HET2544032.1"
                     /translation="MLYPTPIAKLIDSYSKLPGIGIKTATRLAFYTIGMSADDVNEFA
                     KNLLSAKRELTYCSICGRLTDDDPCSICTDPTRDQTTILVLEDSRDVAAMENIQEYHG
                     LYHVLHGLISPMNGISPDDINLKSLMTRLMDSEVSEVIVATNATADGEATSMYLSRLL
                     KPAGIKVTRLARGLAVGADIEYADEVTLLRAIENRTEL"
     gene            59018..60061
                     /locus_tag="VQ540_000154"
     CDS             59018..60061
                     /locus_tag="VQ540_000154"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HET2544033.1"
                     /translation="MKQTIILLYGGRSAEREVSVLSAESVMRAVNYDRFTVKTFFISQ
                     SGDFIKTQEFSHAPGQEDRLMTNETIDWDKKVAPSAIYEEGAVVFPVLHGPMGEDGSV
                     QGFLEVLKMPYVGCNILSSSLAMDKITTKRVLESAGIAQVPYVAIVEGDDVTAKIAEV
                     EEKLAYPVFTKPSNMGSSVGISKSENQEELRQALKLAFRYDSRVLVEQGVNAREIEVG
                     LLGNYDVKSTLPGEVVKDVAFYDYDAKYIDNKITMDIPAKISDDVVAVMRQNAETAFR
                     AIGGLGLSRCDFFYTDKGEIFLNELNTMPGFTQWSMYPLLWDNMGISYPELIERLVDL
                     AKESFDKREAHLI"
     gene            60145..61518
                     /locus_tag="VQ540_000155"
     CDS             60145..61518
                     /locus_tag="VQ540_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HET2544034.1"
                     /translation="MKLTIHEVAQVVGAKNDISIFEDTQLEKAEFDSRLIGTGDLFVP
                     LKGVRDGHDFIERAFENGAAATLSEKEVANHPYILVDDVLTAFQQLAAYYLEKTAVDV
                     FAVTGSNGKTTTKDMLAHLLSTRYKTYKTQGNYNNEIGLPYTVLHMPEGTEKLVLEMG
                     QDHLGDIHLLSELARPKTAIVTLVGEAHLAFFKDRSEIAKGKMQIADGMASGSLLLAP
                     ADPIVEDYLPTDKKVVRFGQGAELEITDLVERKDSLTFKANFLEQVLDLPVTGKYNAT
                     NAMIASYVALQEGVSEEQIRLAFQHLELTRNRTEWKKAANGADILSDVYNANPTAMKL
                     ILETFSAIPANEGGKKIAVLADMKELGVQSVQLHNQMILSLSPDVLDTVIFYGEDIAE
                     LAQLASQMFPIGHVYYFKKTEDQDQFEDLVKQVKESLGAHDQILLKGSNSMNLAKLVE
                     SLENEDK"
     gene            61505..62116
                     /locus_tag="VQ540_000156"
     CDS             61505..62116
                     /locus_tag="VQ540_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HET2544035.1"
                     /translation="MKTSDFVKYLQRMIAITDTGLTFTKDPFDRERYEDLRDLLSEML
                     NQASDLDSEEVAEVLKPTSAYATPLMDVRAWIVEDEKICLVRGQGEDSWALPGGFGEV
                     GYSPTENILKEIEEETGFKAKVERLLAVFDTNRFQLQSKQYAKFVFECKLLDGQFQEN
                     QEIADLQFFAIDPLPNLSEKRITKEQIEILWQVYQGQREQYLD"
     gene            62207..62911
                     /locus_tag="VQ540_000157"
     CDS             62207..62911
                     /locus_tag="VQ540_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001055242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02206 family membrane protein"
                     /protein_id="HET2544036.1"
                     /translation="MNLWDIFFTTQATEPPKFDLFWYVSLFTLLALTFYTAHRYREKK
                     VYQRFFQILQTVQLILLYGWYWVNHMPLSESLPFYHCRMAMFVVLLLPGQSKYKQYFA
                     LLGTFGTLAAFVYPVPDAYPFPHITILSFIFGHLALLGNSLVYLLRQYNARLLDVKGI
                     FLMTFALNALIFVVNLVTGGDYGFLTKPPLVGDHGLVANYLLVSIVLVATISLTKKIL
                     EFFLAQEAEKMIAKEA"
     gene            63130..64503
                     /gene="ftsA"
                     /locus_tag="VQ540_000158"
     CDS             63130..64503
                     /gene="ftsA"
                     /locus_tag="VQ540_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000090410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HET2544037.1"
                     /translation="MAREGFFTGLDIGTSSVKVLVAEQRNGELNVIGVSNAKSKGVKD
                     GIIVDIDAAATAIKSAISQAEEKAGISIKSVNVGLPGNLLQVEPTQGMIPVTSDTKEI
                     TDQDVENVVKSALTKSMTPDREVITFIPEEFIVDGFQGIRDPRGMMGVRLEMRGLLYT
                     GPRTILHNLRKTVERAGVQVENIIISPLAMVQSVLNEGEREFGATVIDMGAGQTTVAT
                     IRNQELQFTHILQEGGDYVTKDISKVLKTSRKLAEGLKLNYGEAYPPLASKETFQVEV
                     IGEVEAVEVTEAYLSEIISARIKHILEQIKQELDRRRLLDLPGGIVLIGGNAILPGMV
                     ELAQEVFGVRVKLYVPNQVGIRNPAFAHVISLSEFAGQLTEVNLLAQGAIKGENDLSH
                     QPISFGGMLQKTAQFVQSTPVQPAPAPEVESVAPTEPMADFQQASQNKPKLADRFRGL
                     IGSMFDE"
     gene            64520..65779
                     /gene="ftsZ"
                     /locus_tag="VQ540_000159"
     CDS             64520..65779
                     /gene="ftsZ"
                     /locus_tag="VQ540_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000144288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HET2544038.1"
                     /translation="MTFSFDTAAAQGAVIKVIGVGGGGGNAINRMVDEGVTGVEFIAA
                     NTDVQALSSTKAETVIQLGPKLTRGLGAGGQPEVGRKAAEESEETLTEAISGADMVFI
                     TAGMGGGSGTGAAPVIARIAKDLGALTVGVVTRPFGFEGSKRGQFAVEGINQLREHVD
                     TLLIISNNNLLEIVDKKTPLLEALSEADNVLRQGVQGITDLITNPGLINLDFADVKTV
                     MANKGNALMGIGIGSGEERVVEAARKAIYSPLLETTIDGAEDVIVNVTGGLDLTLIEA
                     EEASQIVNQAAGQGVNIWLGTSIDESMRDEIRVTVVATGVRQDRVEKVVAPQARSATN
                     YRETVKPAHSHGFDRHFDMAETVELPKQNPRRLEPTQASAFGDWDLRRESIVRTTDSV
                     VSPVERFEAPISQDEDELDTPPFFKNR"
     gene            65784..66455
                     /locus_tag="VQ540_000160"
     CDS             65784..66455
                     /locus_tag="VQ540_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HET2544039.1"
                     /translation="MNVKENTELVFREVAEASLSAHRESGSVSVIAVTKYVDVPTAEA
                     LLPLGVHHIGENRVDKFLEKYEALKDRDVTWHLIGTLQRRKVKDVIQYVDYFHALDSV
                     KLAGEIQKRSDRVIKCFLQVNISKEESKHGFSREELLEILPELARLDKIEYVGLMTMA
                     PFEASSEQLKEIFKATQDLQREIQEKQIPNMPMTELSMGMSRDYKEAIQFGSTFVRIG
                     TSFFK"
     gene            66465..67004
                     /locus_tag="VQ540_000161"
     CDS             66465..67004
                     /locus_tag="VQ540_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HET2544040.1"
                     /translation="MSLKDRFDRFIDYFTEDEDSSLPYEKRDEPVFTPVNSSQEPALP
                     MNQPSQSAGTKENNITRLHARQQELANQSQRATDKVIIDVRYPRKYEDATEIVDLLAG
                     NESILIDFQYMTEVQARRCLDYLDGACHVLAGNLKKVASTMYLLTPVNVIVNVEDIRL
                     PDEDQQGEFGFDMKRNRVR"
     gene            67004..67267
                     /locus_tag="VQ540_000162"
     CDS             67004..67267
                     /locus_tag="VQ540_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HET2544041.1"
                     /translation="MIFLIRMIYNAVDIYSLILVAFAVMSWFPGAYESSLGRWIVALV
                     KPVLAPLQRLPLQIAGLDLSVWVAIVLVRFLGENLVRFLAMIG"
     gene            67264..67948
                     /locus_tag="VQ540_000163"
                     /pseudo
     CDS             67264..67948
                     /locus_tag="VQ540_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398113.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
     gene            67957..68745
                     /gene="divIVA"
                     /locus_tag="VQ540_000164"
     CDS             67957..68745
                     /gene="divIVA"
                     /locus_tag="VQ540_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIVA"
                     /protein_id="HET2544042.1"
                     /translation="MPITSLEIKDKTFGTRFRGFDPEEVDEFLDIVVRDYEDLVRANH
                     DKNLRIKSLEERLSYFDEIKDSLSQSVLIAQDTAERVKQAAHERSNNIIHQAEQDAQR
                     LLEEAKYKANEILRQATDNAKKVAVETEELKNKSRVFHQRLKSTIESQLAIVESSDWE
                     DILRPTATYLQTSDEAFKEVVSEVLGEPIPAPIEEEPIDMTRQFSQAEMEELQARIEV
                     ADKELSEFEAQIKQEVETPTPVVSPQVEEEPLLIQLAQCMKNQK"
     gene            69093..71885
                     /locus_tag="VQ540_000165"
     CDS             69093..71885
                     /locus_tag="VQ540_000165"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HET2544043.1"
                     /translation="MKLKDTLNLGKTEFPMRAGLPTKEPVWQKEWEDAKLYQRRQELN
                     QGKPHFTLHDGPPYANGNIHVGHAMNKISKDIIVRSKSMSGFYAPFIPGWDTHGLPIE
                     QVLSKQGVKRKEMDLVEYLKLCREYALSQVDKQREDFKRLGVSGDWENPYVTLTPDYE
                     AAQIRVFGEMANKGYIYRGAKPVYWSWSSESALAEAEIEYHDLVSTSLYYANKVKDGK
                     GVLDTDTYIVVWTTTPFTITASRGLTVGADIDYVLVQPAGEARKFVVAAELLTSLSEK
                     FGWADVQVLETYRGQELNHIVTEHPWDTAVEELVILGDHVTTDSGTGIVHTAPGFGED
                     DYNVGIANNLEVAVTVDERGIMMKNAGPEFEGQFYEKVVPTVIEKLGNLLLAQEEISH
                     SYPFDWRTKKPIIWRAVPQWFASVSKFRQEILDEIEKVKFHSEWGKVRLYNMIRDRGD
                     WVISRQRAWGVPLPIFYAEDGTAIMVAETIEHVAQLFEEHGSSIWWERDAKDLLPEGF
                     THPGSPNGEFKKETDIMDVWFDSGSSWNGVVVNRPELTYPADLYLEGSDQYRGWFNSS
                     LITSVANHGVAPYKQILSQGFALDGKGEKMSKSLGNTIAPSDVEKQFGAEILRLWVTS
                     VDSSNDVRISMDILSQVSETYRKIRNTLRFLIANTSDFNPAQDTVAYDELRSVDKYMT
                     IRFNQLVKTIRDAYANFEFLTIYKALVNFINVDLSAFYLDFAKDVVYIEGAKSLERRQ
                     MQTVFYDILVKITKLLTPILPHTAEEIWSYLEFEAEDFVQLSELPEVQTFANQEEILD
                     TWAAFMDFRGQAQKALEEARNAKVIGKSLEAHLTVYPNEVVKTLLEAVNSNVAQLLIV
                     SELTIAEEPAPEAALSFEDVVFTVERAAGEVCDRCRRIDPTTAERSYHAVICDHCASI
                     VEENFADAVAEGFEEK"
     gene            72295..72657
                     /locus_tag="VQ540_000166"
     CDS             72295..72657
                     /locus_tag="VQ540_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000842495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2544044.1"
                     /translation="MKSSGIVGLVGGILLLICPFVLLGTAVNTAATTLNGGATAGAFS
                     GVALLLNALKIANLVLGIIAIVYYKGDKHVGAAPSVLMIVSGEVSLIPFLGWVGGILA
                     IIGGSLFLATLKKFKSEE"
     gene            73192..73884
                     /locus_tag="VQ540_000167"
     CDS             73192..73884
                     /locus_tag="VQ540_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006703946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate mutase"
                     /protein_id="HET2544045.1"
                     /translation="MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIK
                     EAGIEFDQAYTSVLKRAIKTTNLALEASDQLWVPVEKSWRLNERHYGGLTGKNKAEAA
                     EQFGDEQVHIWRRSYDVLPPNMDRDDEHSAHTDRRYASLDDSVIPDAENLKVTLERAL
                     PFWEDKIAPALKDGKNVFVGAHGNSIRALVKHIKGLSDDEIMDVEIPNFPPLVFEFDE
                     KLNVVSEYYLGK"
     gene            73937..76348
                     /locus_tag="VQ540_000168"
     CDS             73937..76348
                     /locus_tag="VQ540_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000620712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HET2544046.1"
                     /translation="MIRNKKQDYVLAYKQPASTTYMGWEEEALPIGNGSLGAKVFGLI
                     GAERIQFNEKSLWSGGPLPDSSDYQGGNLQDQYVFLAEIRQALEKRDYNLAKELAEQH
                     LIGPKTSQYGTYLSFGDIHIEFSQQGTTLSQVTDYQRQLNISKALATTSYVYKGTRFE
                     RKAFASFPDDLLIQCFTKEGLETLDFTIELSLTCDLASDGKYEQEKSDYKECKLDITD
                     SHILMKGRVKDNDLRFASYLAWETDGDIRVWSDRVQISGASYANLFLAAKTDFAQNPA
                     SNYRKKLDLEQQVIDLVDTAKEKGYTQLKSRHIEDYQALFQRVQLDLEADVDASTTDD
                     LLKNYKPQEGQALEELFFQYGRYLLISSSRDCPDALPANLQGVWNAVDNPPWNSDYHL
                     NVNLQMNYWPAYVTNLLETVFPVINYVDDLRVYGRLAAVKYAGIVSQKGEENGWLVHT
                     QATPFGWTAPGWDYYWGWSPAANAWMMQTVYEAYSFYRDQDYLREKIYPMLRETVRFW
                     NAFLHKDQQAQRWVSSPSYSPEHGPISIGNTYDQSLIWQLFHDFIQAAQELGLDEDLL
                     TEVKEKSDLLNPLQITQSGRIREWYEEEEQYFQNEKVEAQHRHASHLVGLYSGNLFSY
                     KGQEYIEAARAILNDRGDGGTGWSKANKINLWARLGDGNRAHKLLAEQLKTSTLPNLW
                     CSHPPFQIDGNFGATSGMAEMLLQSHAAYLVPLAALPDAWSTGSVSGLMARGHFEVSM
                     SWEDKKLLQLTILSRSGGDLRVSYPDIEKSVIKMNQEKIKAKCMGKDCISVATAEGDL
                     VQFYF"
     gene            76598..77299
                     /locus_tag="VQ540_000169"
     CDS             76598..77299
                     /locus_tag="VQ540_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2544047.1"
                     /translation="MAYIEMKHCYKRYQVGDTEIVANRDVNFEIEKGELVIILGASGA
                     GKSTVLNLLGGMDTNDEGEIWIDGVNIADYSSHQRTNYRRNDVGFVFQFYNLVSNLTA
                     KENVELASEIVTDALNPDQVLTDVGLAHRLNNFPAQLSGGEQQRVSIARAVAKNPKIL
                     LCDEPTGALDYQTGKQVLKILQDMSRQKGATVIIVTHNGALAPIADRVIQMHDASVKD
                     VVLNQHPQDIDSLEY"
     gene            77301..80001
                     /locus_tag="VQ540_000170"
                     /pseudo
     CDS             77301..80001
                     /locus_tag="VQ540_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595876.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
     gene            complement(80097..80588)
                     /gene="tpx"
                     /locus_tag="VQ540_000171"
     CDS             complement(80097..80588)
                     /gene="tpx"
                     /locus_tag="VQ540_000171"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol peroxidase"
                     /protein_id="HET2544048.1"
                     /translation="MVTFLGNPVSFTGKQLQVGDKALDFSLTTTDLSKKSLADFDGKK
                     KVLSVVPSIDTGICSTQTRRFNEELAGLDNTVVLTVSMDLPFAQKRWCGAEGLDNAIM
                     LSDYFDHSFGRDYALLINEWHLLARAVFVLDTDNTIRYVEYVDNINSEPNFEAAIAAA
                     KAL"
     gene            complement(80711..81640)
                     /gene="psaA"
                     /locus_tag="VQ540_000172"
     CDS             complement(80711..81640)
                     /gene="psaA"
                     /locus_tag="VQ540_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000733059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding
                     lipoprotein/adhesin PsaA"
                     /protein_id="HET2544049.1"
                     /translation="MKKLGTLLVLFLSAIILVACASGKKDTTSGQKLKVVATNSIIAD
                     ITKNIAGDKIDLHSIVPIGQDPHEYEPLPEDVKKTSEADLIFYNGINLETGGNAWFTK
                     LVENAKKTENKDYFAVSDGVDVIYLEGQNEKGKEDPHAWLNLENGIIFAKNIAKQLSA
                     KDPNNKEFYEKNLKEYTDKLDKLDKESKDKFNKIPAEKKLIVTSEGAFKYFSKAYGVP
                     SAYIWEINTEEEGTPEQIKTLVEKLRQTKVPSLFVESSVDDRPMKTVSQDTNIPIYAQ
                     IFTDSIAEQGKEGDSYYSMMKYNLDKIAEGLAK"
     gene            complement(81672..82520)
                     /locus_tag="VQ540_000173"
     CDS             complement(81672..82520)
                     /locus_tag="VQ540_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000559784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HET2544050.1"
                     /translation="MIAEFIDGLQKFHFLQNALITAIVVGIVAGAVGCFIILRGMSLM
                     GDAISHAVLPGVALSFILGLDFFIGAIVFGLLAAIIITYIKGNSIIKSDTAIGITFSS
                     FLALGIILIGVAKSSTDLFHILFGNILAVQDTDMFITMGVGAAILLLIWIFFKQLLIT
                     SFDELLAKAMGMPVNFYHYLLMVLLTLVSVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKSMIFLSSTFGATASVLGLFIGYSFNVAAGSSIVLTAASFFLISFFIAPKQRYLKLK
                     NKHLLK"
     gene            complement(82517..83239)
                     /locus_tag="VQ540_000174"
     CDS             complement(82517..83239)
                     /locus_tag="VQ540_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HET2544051.1"
                     /translation="MIRIENLSVSYKETLALKDISLVLHGPTITGIIGPNGAGKSTLL
                     KGMLGIIPHQGQAFLDDKEVKKSLHRIAYVEQKINIDYNFPIKVKECVSLGLFPSIPL
                     FRSLKAKHWKKVQEALEIVGLADYAERQISQLSGGQFQRVLIARCLVQEADYILLDEP
                     FAGIDSVSEEIIMNTLRDLKKAGKTVLIVHHDLSKIPHYFDQVLLVNREVIAFGPTKE
                     TFTETNLKEAYGNQLFFNGGDL"
BASE COUNT        25199 a        15191 c        18399 g        24544 t
ORIGIN      
        1 taaccatgcg ctatctaagg agagaagcaa ggttgagaac atctttgcca aagtaaaaac
       61 gtttaaaatg ttttcaacaa cctatcgaaa tcatcgtaaa cgcttcggat tacgaatgaa
      121 tttgattgct ggcattatca atcatgaact aggattctag ttttgcagga agtctactac
      181 tttccttatt gtctgtaaat ctactgacct tgttgtttat cccagtcatg gtttctagtt
      241 cgggctcaga gtttcaaagt ggatggcaag agcatcaatt gattgctgag aaggttagta
      301 aaacacttga taagacattt gataaggatg tcagagaaat tccgaccagt cagttttatc
      361 aaaaatttgt agatgagatg ggaaggattt actcaggaaa tttgatcctc caggagctga
      421 taactgtgaa tggagcttat aaagctactt atatcggtga actctctagc aactaatcat
      481 tctttaaaat gatgaccaat aagaggcttg atttggtgaa tcaagtcttt tttctctctt
      541 ttactgccat ttgtgataaa atagtataga acgatttttt acatgaatga taaaacagag
      601 gtaaatatga caatcggtat tgataagatt ggttttgcga ccagtcaata tgtcttgaaa
      661 ttacaagact tagcagaagc gaggggaatt gaccctgaaa aattaagtaa aggactctta
      721 ctcaaggaat tgagtattgc gcccctaact gaggacatcg tgaccttggc ggccagtgct
      781 agtgactcta ttttaactga gcaagaaaga caagaagttg acatggtcat tgtggctacc
      841 gagtcaggaa ttgaccagag taaggctgcg gccgtctttg tgcatggctt gctgggcatc
      901 cagccctttg ctcgtagttt cgagattaaa gaagcctgct atggggcgac agctgccctc
      961 cattatgcca aattgcatgt ggaaaattct ccggagtcca aggtcttggt cattgccagt
     1021 gatattgcca aatatggtat tgaaactccg ggagaaccaa ctcaaggtgc tggaagtgta
     1081 gctatgttga ttacacaaaa tccacgcatg atggccttta ataatgacaa tgtagctcag
     1141 acccgtgaca tcatggattt ctggcgacca aattactcga caactcctta tgtaaatggt
     1201 gtctattcta cccaacaata cttggatagt ttgaaaacga cttggcttga atatcaaaaa
     1261 cgctaccagc ttactctgga tgattttgcg gctgtttgtt tccacttgcc ttatcctaaa
     1321 ttagcgctaa aaggcttgaa aaaaatcatg gataagagcc tgcctcaaga gaaaaaagac
     1381 ctcttacaaa agcattttga ccagtctatt ctctacagtc aaaaggtggg gaatatctac
     1441 acaggttcac ttttccttgg acttttgtct ctcttggaaa atgcagatag cttgaaagct
     1501 ggggataaaa tcgcccttta tagttacgga agtggagctg tggctgagtt cttcagtggt
     1561 gaattggttg aaggatatga agcttatttg gataaagacc gcttgaacaa gctcaaccaa
     1621 cgaactgcct tatccgttgc agactatgaa aaggtctttt ttgaggaagt aaacttggat
     1681 gaaacaaact ctgcccagtt tgctggctat gaaaatcaag attttgcctt ggttgaaatt
     1741 ctcgaccacc aacgccgtta tagcaaggtt gaaaaataat gaagataagt tggaatggat
     1801 tttctaaaaa atcataccaa gagcgcctcg agctgttaaa agctcaggcg ctccttagtc
     1861 ctgagagaca agctagtctg gagaaggatg aacagatgag tgtgactgtg gcagaccagc
     1921 tgagtgagaa tgtagtggga actttttctc tgccttattc gctggttccg gaggtacttg
     1981 tcaacggtca ggaatacacc gttccctatg tgacagaaga accctctgtg gttgcggcgg
     2041 ccagctatgc cagcaaaatc atcaagcgtg caggtggttt tactgcacaa gtccatcagc
     2101 gccagatgat tgggcaggta gccctttatc aagttgctaa tcctaaacta gcgcaagaga
     2161 agattgccag caagaaagcg gagctcttgg agtttgccaa tcaagcctat ccttctatcg
     2221 ttaaacgtgg aggtggggcg cgtgatctgc atgtcgagca gataaaaggc gaaccagact
     2281 ttctcgttgt ttatattcat gtcgataccc aggaagccat gggtgccaat atgctcaaca
     2341 ccatgctgga agccttgaaa ccagtcttag aagaactcag tcagggacag agtctcatag
     2401 gaatcctgtc caactacgcg accgattctc tggtgactgc aagctgtcgc atggcctttc
     2461 gctacttgag ccgccaaaag gatcaaggac gagagattgc ggagaaaatt gcgttggcta
     2521 gtcagtttgc gcaggctgat ccttaccgag ctgctactca taataaagga atttttaatg
     2581 gtattgatgc gattttgatt gccactggta atgactggcg tgccatcgaa gctggggccc
     2641 atgcctttgc cagtcgagat ggacgctatc aaggtcttag ttgctggacg ctggaccttg
     2701 aaagagaaga attggtcggt gagatgaccc tgcccatgcc tgtagcgact aagggtggct
     2761 ctatcggcct caacccacgt gtagctttca gtcatgatct actaggaaat ccttctgcca
     2821 gagaattagc ccagattatc gtgtccatcg gtcttgccca aaattttgca gccctcaaag
     2881 ctttggtaag tacgggcatc cagcaaggcc acatgaaact acaggccaaa tccctagctc
     2941 tcctagctgg ggctagtgaa tctgaagttg ctcccctagt agagcgcctc atctcagata
     3001 aaacctttaa cctagagaca gcccagcgct atctcgaaaa tttaagatca taaaaaactc
     3061 agacgaatcg gtctgagttt tcttgtgttt aaatactttt tcctggtaat agtgtaactg
     3121 gtaagaagta accagttgtg gcaacttcct tgccttcaat cttttgcaag agaagatcaa
     3181 tagtgagaca agcaatctct tccaaaggtt gcttgatagt agccaattga gggtagtaat
     3241 tttcgataaa gtaggtccca tcatagccga tgaccttgag ctcttttggg acagaaatgc
     3301 ccaattcttg agcgatttta atgaccagaa tagctgtcaa atcatccgaa gcaaaaatgg
     3361 catctggttt ttcccgggtc aagatattct tgatttccat ttcttttctg acgggagaaa
     3421 agtcactgga aacattgata ataggagctt ttgggagtac ggatgcaaaa ccagcgtggc
     3481 gtagtccggt tggcgaattg gaattgtcat tccctgtaat catgatgata gtctgggcac
     3541 ctgtcttgac caaggtttgg gcagcaagaa ccccaccagc atagttgtca gaggagacga
     3601 cagggatgtc tggcgatagg tttcggtcaa aggaaataat cggcgctgtc acacgattgt
     3661 agtcttcgat tcctaggttg tgactaccag aaatgatgcc gtccacctga ttggcttcca
     3721 acatttcgat gtattcgcgt tccttctcag aatcatgttc actgttgcag atgatggtct
     3781 tgtaaccatt tttgaagagt tggtgttcca atttatcaat caattctgca tagaaaacat
     3841 tggaaatatt agggaaaatc aagccgatta acttagctga ttttccttgc agactacgag
     3901 ccaggttgtt gggtttatag cccaattctc gcatggcttc attgactttt tggatggttt
     3961 tctcagatag ataccctttt ttattgataa cccgagaaac ggtagtagga ctgacgcctg
     4021 caagtttggc gacatcagtt agttttgcga ccataatcta attcatagta agttccagtt
     4081 gggtttccag atttgatcag gataccattt tggtccgcat gtgggaagac acgaccagaa
     4141 aatacttttt ctcctttatt gatgaaaatt tcaaagacag agttatcgat gaagattgta
     4201 gcagtagtag cctgattctc gatagggcaa gaacgagttg tcccaaattc ttgggcatac
     4261 tgttctccag cctggctacg atccactgtc acttgaccgt ttacaaggtc aaagttgatt
     4321 gaaagtccct taccttcttt atcagcaagt aagacaatct cgctctggct attagcttcc
     4381 aagttgagtt caagttcgta agtgttcttg gtttgggaac ggtttgagaa ggcttcttca
     4441 gaagcacgaa ggtccttaat agcagcgact ggatactggt agagcttgtc gtctttgata
     4501 gtgagttcct tgaccaaaga gaaggttcct tggtggtcaa aacggtcaga tgggtaagaa
     4561 acatctggca aaccaagcca gctaactgct agagcacgcc catcaggagc gttgaaggct
     4621 tgagttgcat aggcttcgaa accgtaatcc atgttttgaa gttgagacac atctaccatt
     4681 ttggcatttt tagggtcaaa ggaagcccca atcttataca tatttggaaa gatattatcg
     4741 tagtctagaa ctttcttatc caatccttgt ggacagtaga gaaggacagg atgttcctct
     4801 acaaagacca gattaggaca ttccatcatg taggcagtac ggtcgttagc aaagtcaagg
     4861 tcgccaactg cttgccagtt tgtgtagtcg ttattgacag ccttgtagag acggacgaag
     4921 ccttttttct ccaagtcctg tccaccgacg acagcatagt attgactttt aaagttaaaa
     4981 atttgtggat cgcggaagtg gtcagtagag tctgctggct ggtcaatcaa gatcttgtca
     5041 atctttgtaa tcttaccctc cttgtccatc aaagcaccga tctggtatgg gtgacggatc
     5101 cagttttcat cgcgaacatt tcctgtataa aataggaata agttatcgcc aaattgcatg
     5161 gcagaaccag agtaggcacc gtggctatct aatggagtat ctggtaaaac tttgattcca
     5221 gtttctttaa agtgaaccaa atcatcactt tctagctgtg cccaagattt caaaccgtgg
     5281 gctgcaccaa aaggaaaatt ctggtaaaag aggatccact tgccatcaaa gtaagaaaag
     5341 ccatttgggt cgttgagaag tcctgttttt ggctcaacat ggtaatgagt atgccatgga
     5401 gattgtgcca tattttcctt tatatgttga atttcttctt gcgtccaatc ttgataaagt
     5461 ctgtaacgac gctcagttgt ccattccatt cattcctcca aaaatcttat cacttttaat
     5521 agtaactgtt ttcgataaaa aatgcaagcc ttttatgtta aaaaagagga aaaactgtca
     5581 aacgattatc ataaaataaa tacaggaaat caatcaaatt tttacgaaaa tgtgaaagat
     5641 aatgaaataa aagacttttt aaccaaggtt tcaaacttat ttttcaagga attcctgatg
     5701 aaacagtcaa aaacaatcaa tctaaaactt gcccactaag tggatagaat attttttctg
     5761 caaaacgctt gacatatttt taaaacatga taaaataata gtcgtaaggg cgaataaaat
     5821 cgctttcaaa caagaacaaa atgttatata aggagatttt tgcaaatgaa caatcaggaa
     5881 attgcaaaaa aagtcatcga tgccttgggc ggacgtgaaa atgtcaatag tgttgcccac
     5941 tgtgcgactc gtctacgtgt catggtcaaa gatgaagaga aaatcaataa agaagtgatt
     6001 gagaacttgg aaaaagttca aggtgctttc tttaactcag ggcaatacca aattatcttt
     6061 ggtacaggta cagttaacaa aatgtacgat gaagttgttg tacttggctt accaacatca
     6121 tctaaggatg acatgaaagc agaagttgct aaacaaggga actggttcca acgtgctatc
     6181 cgtactttcg gtgatgtttt cgttccaatc atcccagtta tcgtagcgac aggtctcttc
     6241 atgggtgtgc gtggtctttt caacgctctt gaaatgccac ttccaggtga ctttgcaact
     6301 tacacacaaa tcttgacaga tacagccttc atcatcttgc caggtttggt tgtgtggtca
     6361 accttccgtg tatttggtgg aaatcctgcc gttggtatcg ttcttggtat gatgcttgtc
     6421 tctggctcac ttccaaacgc ttgggcagtt gctcaaggtg gtgaagtaac agcgatgaac
     6481 ttctttggtt tcatccctgt tgttggtttg caaggttccg ttcttccagc cttcatcatc
     6541 ggggttgtcg gagctaaatt tgaaaaagct gtccgcaagg ttgttccaga tgtcattgac
     6601 ctcttggtaa caccattcgt gacacttttg gtcatgtcta tccttggact ctttgtcatt
     6661 ggaccagttt tccacgttgt tgaaaactac atccttattg ctacaaaagc gattcttagc
     6721 atgccatttg gtcttggtgg tttcttgatt ggtggggttc accaattgat cgtcgtgtca
     6781 ggtgtgcacc acatcttcaa cttgcttgaa gtgcaattac ttgctgctga ccatgctaac
     6841 ccattcaacg ctatcatcac agctgctatg acagctcaag gtgctgctac tgttgcggtt
     6901 ggtgttaaaa caaaaaatcc aaaactgaaa acacttgctt tcccggctgc tctttctgcc
     6961 ttcctaggta ttacagagcc tgctatcttc ggggtgaact tgcgcttccg taaaccattc
     7021 ttcctttcat tgattgctgg tgcaatcggt ggtggattgg cttctatcct tggacttgct
     7081 ggtactggta atggtatcac catcatccct ggtacaatgc tttatgttgg taacggacaa
     7141 cttccacaat accttcttat ggtagctgta tcatttgccc ttggttttgc tcttacttac
     7201 atgtttggtt acgaagatga agtagacgca actgcagctg caaaacaagc tgaagtggct
     7261 gaagaaaaag aagaagttgc gccagcagct cttcaaaatg aaacacttgt aactcctatc
     7321 gtcggtgatg ttgtcgctct tgctgatgtc aatgacccag tcttctcaag tggagctatg
     7381 ggacaaggta tcgctgtgaa accaagtcaa ggcgtggtct atgcactagc tgatgctgaa
     7441 gtttcaattg cctttccaac agggcacgct tttggtttga aaacaagaaa tggtgctgaa
     7501 gttttgattc acgttggtat tgacactgta tctatgaacg gtgacggttt tgaagcaaaa
     7561 gttgctcaag gtaataaggt gaaagctggc gatgttcttg gaacatttga ctcaaacaaa
     7621 atcgctgcag ctggacttga tgatacaaca atggttatcg ttacaaatac agctgactac
     7681 gcttcagtag ctccagtcgc aacaggttca gtttcgaagg gggatgctgt gatcgaagtg
     7741 aaaatctaat caatcctctc taatgtgaaa acgaacaaat gacatgtttg ttcgttttta
     7801 ttagatagta agatttacag aggaaaatct aaaaaataga gacatttaga ctttcgaagt
     7861 atgctataat aaagaaaata aaaacaagag gtttatcatg acaaaattat atggaagctt
     7921 ggaagcgggc ggtacaaagt ttgtctgtgc tgtcggtgat gaaaacttta acgttgtaga
     7981 aaaaacacaa tttccaacaa caactccaat cgaaacaatc gataaaacca ttgagttctt
     8041 ctcaaaattc gataaccttg ctggtcttgc agttggttca tttgggccga ttgatattga
     8101 caaaaactca aaaacttatg gctttatcac gacgactcca aaaccaaact gggcaaatgt
     8161 ggacttgctt ggtgcccttc gtcgcgccct aaacgtgcca atgtacttca caacagacgt
     8221 aaacagctct gcttacggtg aaatggttgc tcgtaacaat gctggtggtc gtatcgaaaa
     8281 cttggtttac tacacaatcg gtacaggtat cggtgcaggc gtcatccaac gtggtgagtt
     8341 tatcggtggt gtgggtcacc ctgaaatggg tcattattat gttgctagac acccaatgga
     8401 tattgaaaaa gagtttaagg gtgtttgtcc tttccataag ggatgtctag aaggttatgc
     8461 agctggtaca agtttggaag ctcgtacagg tgtacgtggg gaaactattg aactcaacaa
     8521 ccctgtttgg gatgttcaag cctactatat cgctcaagct gcggttaatg cgacagtgac
     8581 tttccgccca gacgtgattg tctttggtgg aggggtcatg gctcaacaac atatgctgga
     8641 ccgtgtccgt gagaaattta catctcttct taatggttac ctaccagtac cagatgtgcg
     8701 tgactatatc gtgacgccag cagtcgcagg aaatggttct gccacacttg ggaactttgt
     8761 tcttgcaaaa gaagtttcaa aataaagcac aaaatccgct tgggaaacca aacggatttt
     8821 gtggttgaaa acaatatttt tgagcctttc cttaagtgat tacggacggt agcgactttc
     8881 ttcgaaattc catacctaaa ctttgagcct agtgtctcaa agtttccgaa tacctgaaac
     8941 cattagattt caggtgtttc tatcacggcg gaaaggctag gtaagtcctc gcctcactat
     9001 cgaaaaatat gcataatttc cataccaaag tatatttagt atcaagctat agttaatcta
     9061 cgctttaaaa atccacttgg gaaaccaaac ggatttttta cgtgtcaaag catttgccag
     9121 aaaaagtcaa taatataggt cagaccgtag gtataaacca cgagggtaaa gggtttggtc
     9181 agaatgatga tagtcatgta gcgcttgaaa ctcatcttgg tcagggcggc cagcatacag
     9241 agaaagtcag ctgggctaat gggccaaatc atcataaaaa taaagaagcg gtcaaaacga
     9301 ttgcccttat ctagccagcc gatgtacttg tcgtaggtgc gcttgctgac gacagactgg
     9361 acaaaggcag ctccgtatag gcgcactaga taaaagataa tggcacagcc aatcacgatg
     9421 ccgatatagt tgtagatagt cccgatgatg tgcccgtaga taaagacccc agccaccgag
     9481 gtcaaggccc ctggaatgat agggacgaca gtctgtaaaa tctgtaaaaa gataaagaga
     9541 ggtggacccc agatgcctgc ctgctggata aaggcagaga gggtttcctt ggattgtaaa
     9601 atcccagcct gataagccca aatacagaaa atcaaactcc caaccccacc gacaatcgat
     9661 gagatattga taactcgctg cagaagggga gaaacagctt tcatttgttt atcctgtgac
     9721 atgtaaactc ctcatagata gtatatttct actataccat attttggagg agaaaggggg
     9781 aatgagtctt ttttgataag gaatagaaag taaatagccc ttcgagactt agaataggtc
     9841 tgtcaactaa aggttatatg cattctaggt ttcgaataat cgcaattcca taaatttaaa
     9901 agtattctaa gtttcgaata gcttatctga gataattttg aggcattcgc gctttcgaat
     9961 agtcattttc cctaaagttt atatgtattc tgaagctaga aagactaaaa tataaaagta
    10021 gtaagagtct ctctctgatg gacgtaattt atggctagta tgaatccttt gaattgttag
    10081 ttaattttaa tattaatcag ttctgaaata attactaaat atagttagat ggtgagttaa
    10141 ttattgctaa atttcaagtt caagttagtc atccagaagt cttctctggg ggacttgtag
    10201 ttcaagcatt ttttaggata gttgttaatc cacttttcga taaatgcgac ttcctttgta
    10261 gttgttttct tagttccctg aggtaaccat ctatgaatga gcctgttgtg attttcatta
    10321 gatcctatag tgatgtgcat aatagatata gcagattgaa actagaatag tatacatcta
    10381 cttctaaaac attgttagaa atcaatttga ctgtcctgat caatttgtcc tgtttttatt
    10441 tcattttact atataatcct tagaaaacat atcggacaag cggttgaatt ccgttccgtc
    10501 cattagtaga taaaggatta ctccttcttg aaatgacaga tgaacttgtt tcttataaaa
    10561 atgttgtctg aaactattag cctttttcca gaagttttag aggaagaaaa ctttacgagg
    10621 aaaaaggagt tactcaaata acaattcagg attaaaaata gacagttgag gagcggaagg
    10681 tataaattaa gtttgctact gtataatgga tttatcacta atactcttcg aaaatctctt
    10741 caaaccacgt cagcttcgcc ttgccgtaga tatagttact gacttcgtca gttctatcca
    10801 caacctcaaa acagtgtttt gagctgactt cgtcagtttt atctgcaacc tcaaagctgt
    10861 actttgagca gcctacggct agcttcctag tttgctcttt gcttttcatt gagtataaaa
    10921 gtgctccagg ccatatttta cacagcaata gtcttctaaa aatggacaaa aacattgtaa
    10981 aggctatcaa aaaggagtat aatgagtgca agaaatttcg gaggtgaaag atgctagaag
    11041 taagaagtct agagaaaagt tttggctcca agcaagtttt gtttggtatt gactttcaag
    11101 cgcgaccagg tcgtattttg ggactagtcg gaaaaaatgg tgctggaaaa acaacgattt
    11161 tccatagtat tttgaaattc ctagaatatc agggagaaat cggtctggat ggtcaggata
    11221 ttcgtcagga gacctatgct cggattggtt atctgcctga agaacgcagt ctcatgccta
    11281 aattgacagt tcttgaacaa gttcgctact tggcgactct aaaaggcatg gatgccaaag
    11341 aagtcaaaga aaaactccct caatggatga agaggttgga agtgaaagga aagctgacag
    11401 ataaaatcaa gagtctgtca aaaggaaatc agcagaagat tcagctcatt attactctga
    11461 ttcatgaacc agacctgatt atcttggatg agccttttag tggattggac ccagttaata
    11521 cagaattgct caaacaagtc atttttcagg aaaaagagcg cggagcaacc attatctttt
    11581 ctgaccatgt catgaccaat gttgaggaac tttgtgacga tattctgatg atccgagatg
    11641 gccgtgtggt cttgcacgga ccagttcagg atgtccgcaa tcaatacggg aaaacgcgtc
    11701 tctttgtttc aagtgaacga agcaaggaag aattggaaaa tcttcctcat gtcaaacagg
    11761 tgagcttgac caaacaaggc agttggaaat tgattttgga ggatgagagc gctggaaggg
    11821 aactcttccc aatcttgact caaggtcaat atatcgcaac atttgaccaa caagcgccaa
    11881 ctatcgatga aatctttaaa ctagaatcag gagtggaagt atgagaaata tgtgggttgt
    11941 aatcaaggaa acctatcttc gacatgtcga gtcatggagt ttcttcttta tggtgatttc
    12001 gccgttcctc tttttaggaa tctctgtagg aattgggcat ctccaaggtt cttctatggc
    12061 taaaaataat aaagtggcag tagtgacaac agtgccatct gtagcagaag gactgaagaa
    12121 tgtaaatggt gttaacttcg actataaaga cgaagcaagt gccaaagaag caattaaaga
    12181 agaaaaatta aaaggttatt tgaccattga tcaagaagat agtgttctaa aggcagttta
    12241 tcatggcgaa acatcgcttg aaaatggaat taaatttgag gttacaggta cactcaatga
    12301 actgcaaaat cagcttaatc gttcaactgc ttccttgtct caagagcagg aaaaacgctt
    12361 agagcagaca attcaattca cagaaaagat tgatgaagcc aaggaaaata aaaagtttat
    12421 tcaaacaatt gcagcaggtg ccttaggatt ctttctttat atgattctga ttacctatgc
    12481 gggtgtaaca gctcaggaag ttgccagtga aaaaggcacc aaaattatgg aagtcgtttt
    12541 ttctagcata agggcaagtc actatttcta tgcgcggatg atggctctgt ttctagtgat
    12601 tttaacgcat attgggatct atgttgtagg tggtctggct gccgttttgc tctttaaaga
    12661 tttgccattc ttggctcagt ctggtatttt ggatcacttg ggagatgcta tctcactgaa
    12721 taccttgctc tttattttga tcagtctttt catgtacgta gtcttggcag cattcctagg
    12781 atctatggtt tctcgtcctg aggactcagg gaaagccttg tcgcctttga tgattttgat
    12841 tatgggtggt ttttttggag tgacagctct aggtgcagct ggtgacaatc tcctcttgaa
    12901 gattggttct tatattccct ttatttcgac cttctttatg ccgtttcgaa cgattaatgg
    12961 ctatgcgggg ggagcagaag catggatttc acttgctatt acagtgattt ttgcggtggt
    13021 agcaacagga tttatcggac gcatgtatgc tagtctcgtt cttcaaacgg atgatttagg
    13081 gatttggaaa acctttaaac gtgccttatc ttataaatag aagagccttg cgaaagcgag
    13141 gtttttaaag gtgaaaaggg tggaatcacg aacctaatga tgtacacatt atgtaaacag
    13201 gttgcttgaa aactcaattg tatagtgaac tgaatctgga ataggataat attacttcta
    13261 aaacattctt ataaattgat ttgaattcca aaatcccatc gttccgttct tatttcattt
    13321 tgcgatatag tgaaaggaaa taagtcagct cacaaaaaac gcataatatc aaggattttt
    13381 aacacttgat actatgcgtt ttctaatttt aaagactttt tgcctggtct cttttgttct
    13441 atgagtatgt tacatatcta ggtaaaaatt atttaaagca aattaacctt atttctcaag
    13501 atgtagtagg ttccgagata aaagatagct atgaatatga gttctttaac aatggctata
    13561 cctgctccca tatagaaatg gtcattgagt cctaccagtg aattgacata gaaattagaa
    13621 ctaagattga agaaaagttc aataaatcca atgacgattt ggataccaat gtaggctgca
    13681 acagcgagtg ctgtacggta ttcattgaaa agctgtccaa tggaaatagc caggtagatg
    13741 cagaggattc ctgaaatggt atttagtagg aaggatatac ctgtaagaaa gatctgaggg
    13801 agatgtgttt ctacaaatgt aatcacataa gaaagaggaa tccattctgg agctgttaaa
    13861 gccagaataa taacagcact tagagccaat acagcggtgc taatcaatga ccagataaag
    13921 gcaccgatta gtttggctgt gatgatatgg tgttcagaaa ctggcaaggt caaagtcaga
    13981 tagccttgtc ggtcgtagac actacctttg aagcgtttaa taatcaagaa aatggttgaa
    14041 atcgcaagtg taagcatcaa gccaccaaag actgtagcta gaaaaagtag catagtagcc
    14101 tgactttctt ggtaaggtag atttttaaag ccttgtgtct gtattccgat gagggcagaa
    14161 aggactagca cggctgcgta gagggctaaa taccacttgt taacattttt aaattcgtag
    14221 tgaactaaat tccaaaacat aaataatctc ctttgcttag gccttaaatt cctgacggaa
    14281 gagttggtca atggattcac ctgactcgta gcgaatatca tctacatttc cttgacggac
    14341 gacttttccg tcttttagga agacaatttc atccaagatt ggctcgatat cagaaatcaa
    14401 gtgggtagaa atcaaaacgg tagaagttgg tgagtagttg ttgataatgg tattgaggat
    14461 ataagcacgg gctgctggat ccaccccacc aatgggttca tccaaaacat agagacgagc
    14521 atcacggctc ataaccaaaa tcagttgaac cttttctttg tttccttttg atagtttctt
    14581 gagacgacta ttttcatcaa tgcccaggtc tgcaagtaga tgatgagcgc gttcaagatt
    14641 gaaatcttta tagaaggtct tgaagtaggt tagggcttct ttgaccttca tttgctcatt
    14701 gagataggtc gtatcaggca aataagctac aacggccttg gttgctgggc ttgggtccat
    14761 gtcgttgatg aggacacgtc cttgatctgg ttgtaagagg ccattaatta gtttaatcag
    14821 ggttgttttt cctgagccgt ttggcccaag aaggccgaca atttttccag ctggaatgtc
    14881 aagagaaaca ttttcaaggg ctggtgttgc tccatatgat ttggatacat tttcaaatac
    14941 tagtaatgac ataggcttaa actcctttaa tataatcact gactacgcct ggtagttctt
    15001 ctttttcata gccaaaatgg atcatggagg aaacgaagtg ttccaattct tcttctgata
    15061 attgtttgcg tgactgagcg attagctcct tatccttagt cacaaatcgt ccagttgttc
    15121 gcttgctgta gacaaatcct tctcgttcaa ggtctgataa ggctctttgg atggtattgg
    15181 gattgacacc agcctcgcta gctagctccc tcacggttgg aagttgttga ttgggttcca
    15241 gtgtatggga aacaatctga agcttgattt tctccataat ctgtaaatag atgggttttt
    15301 tgttgtcaaa tgtccaggac atcttagtct cctttctctt atccttttgt cttaactaaa
    15361 taatacaaca aaacaaaaaa cttgtcaagc aaaaagaaga attgttttgg gaatcgctta
    15421 aaaaatggta taatgaaaag aaaacgataa ggagggaaag gatgcgttgt ccaaaatgtg
    15481 gggctaccaa gtcaagtgtt atcgatagtc gccaagcaga agaagggaac accattcgta
    15541 gaagacgtga gtgcgacgaa tgccaacacc gttttacaac ctacgaacga gtagaagaaa
    15601 gaaccttagt ggttgttaaa aaagatggta cacgggaaca attctccaga gataaaatct
    15661 ttaatgggat tatccgctca gcccagaaac gtcctgtgtc aagtgatgaa atcaacatgg
    15721 tagtcaatcg tatcgaacag aaactccgtg gtcgaaatga aaatgaaatt caaagtgagg
    15781 acattggttc actcgtcatg gaggagttgg ctgaattgga cgagattacc tatgtacgtt
    15841 ttgctagtgt ctatcgtagt tttaaggatg tcagtgagtt agagagcttg ctccaacaaa
    15901 tcacccagtc ctctaaaaag aaaaaggaaa gataaatgaa gccaattgac cgtttttctt
    15961 atctaaagaa taatcgggtg tcgcaagata cctcatctct ggtacagtgc tacctcccga
    16021 ttatcggtca ggaggcactg agcctttatc tttatacaat cagtttttgg gataatggta
    16081 gaaaggaata tcttttttca agtatcctca atcatctcaa ctttgggatg gatagactga
    16141 taaaatcatt gaaaatctta tctgctttta atctcttgac cctctatcaa aagggggatg
    16201 tttatcagct agccctccat gctcctctat ctagtcaaga cttcttggag catcctgttt
    16261 atcgcagact cttagagaaa aagattggcg actctgctgt ggaggatttg aaagttgaaa
    16321 gtgctgatgg tgaagaaata cctgtctcac tcaatcaagt ctttccagaa ttggcagaac
    16381 taggcagtca agaagacctt ggtctcaaga agaaagtggc caatgatttt gacttggaac
    16441 attttcgcca gctgatggct cgagatggac ttcgttttgc ggatgagcag tccgatgtct
    16501 taaacctctt tgctattgcc gaggagaaga aatggacttg gtttgaaacc tatcaattgg
    16561 ccaagtcaac agctgtttct caggttattt caaccaaacg catgcgtgaa aaaattgctc
    16621 aaaaaccagt ttcctctgac tttaatccta aggaagcaac cattatcaag gaagctaaaa
    16681 gtaagactgc cctgcagttc ttagcagaaa tcaagcaaac acgcaagggg accattaccc
    16741 aaacagaaag agaacttttg caacagatgg ctggcttggg cttgctggac gaagtcatca
    16801 atatcattct cttgttgacc tttaataagg tggattcggc aaacatcaat gagaaatatg
    16861 ccatgaaggt ggctaatgac tatgcctatc aaaagataca ttcagcagaa gaggccgttt
    16921 tacgaattcg tgagcgaggg cagaaaacaa aaacacaaaa acagaatcag actgccccag
    16981 caaaaaccaa tattcctaaa tggagtaacc cagattataa gaatgaaacc agcgaggaaa
    17041 ctcgtctgga actagaacgt aagaaacaag aactattagc tcgattagaa aaaggaggag
    17101 attagatgga aagtgtcgga gacgtactca aacgtcaacc cagccgtttt tattatcaag
    17161 atttggtcca gaaaatcatg aaggaccctg atgttgcggc ttttatccag caagaatcct
    17221 tgactccaga ggaattaaat cgcagtatct ccaagtttaa tcagtacatc accgagcgtg
    17281 acaagtttct ccgtggggat acggattata ttgccaaagg ctacaagccg attttggtta
    17341 agaatcatgg ctatgcagat gtttcatatg aagaaactcc tgagctaatc gcggctgaaa
    17401 aagaagcggc tattaagaat cgtctcaagc taatcaatct accagccagt ctcaaaaaag
    17461 ctagtttggc tcaagttgat ttggatgatt tgggacgctt gccagttttt gaaaaactat
    17521 tagcctttgt ggagcaatat ccagctattc gaaaaggtct ttacttatat ggagactttg
    17581 gtgtgggtaa aagtttcatg gtggcggcct tagctcatga tttatcagaa aaacgtggtg
    17641 tttcatcaac tctcctccac tatcctagct ttgtcattga tgtcaaaaat gctatcagtg
    17701 atggcaatgt taagaccttg gtggatgaga ttaagctgtc tgaggtcctg attttagatg
    17761 atattggcgc cgagcaatca accgcttggg tgcgtgacga aatcctgcag gtcattctcc
    17821 aatatcggat gcaggaaaat ttaccgacct ttttcacatc caacttcaac tttgaagatt
    17881 tggagaagca ttttgcgaaa gtgaaacatg gaaatgacga aacctgggaa gccagacggg
    17941 tcatggaacg catccgttat ttggctgagg agactcgttt agaaggagta aaccgtcgat
    18001 gacagaaacc attaaattga tgaaggctca tacttcagtg cgcaggttta aagagcaaga
    18061 aattccccaa gtagacttaa atgagatttt gacagcagcc cagatggcat catcttggaa
    18121 gaatttccaa tcctactctg tgattgtggt acgaagtcaa gagaagaaag atgccttgta
    18181 tgaattggta cctcaagaag ccattcgcca gtctgctgtt ttccttctct ttgtcggaga
    18241 tttgaaccga gcagaaaagg gagcccgact tcataccgac accttccaac cccaaggtgt
    18301 ggaaggtctc ttgattagtt cggtcgatgc agctcttgct ggacaaaacg ccttgttggc
    18361 agctgaaagc ttgggctatg gtggtgtgat tatcggtttg gttcgataca agtctgaaga
    18421 agtggcagag ctctttaacc tacctgacta cacctattct gtctttggga tggcactggg
    18481 tgtgccaaat caacatcatg atatgaaacc gagactgcca ctagagaatg ttgtctttga
    18541 ggaagaatac caagaacagt caactgaggc aatccaagct tatgaccgtg ttcaggctga
    18601 ctatgctggg gcgcgtgcga ccacaagctg gagtcagcgc ctagcagaac agtttggtca
    18661 agctgaacca agctcaacta gaaaaaatct tgaacagaag aaattattgt agaaagtgag
    18721 aaattatggc cctaccaact attgccattg taggacgtcc caatgttggg aaatcaaccc
    18781 tatttaatcg gatcgctggt gagcgaatct ccattgtaga agatgtcgaa ggagtgacac
    18841 gtgaccgtat ttatgcaacg ggtgagtggc tcaatcgttc ttttagcatg attgatacag
    18901 gaggaattga tgatgtcgat gctcctttca tggaacaaat caagcaccag gcagaaattg
    18961 ccatggaaga agcagatgtt atcgtctttg tcgtgtccgg taaggaagga attaccgatg
    19021 cagacgaata cgtagcccgt aagctttata agacccacaa accagttatc ctcgcagtca
    19081 acaaggtgga caaccctgag atgagaaatg atatctatga tttctatgct ctcggtttgg
    19141 gtgaaccatt gcctatctca tctgtccatg gaatcggtac aggggatgtg ctagatgcga
    19201 tcgtagaaaa tcttccaaat gaatatgagg aagaaaatcc agatgtcatt aagtttagct
    19261 tgattggtcg tcctaacgtt ggaaaatcaa gcttgatcaa tgctatcttg ggagaagacc
    19321 gtgttattgc tagtcctgtt gctggaacaa ctcgtgatgc cattgatacc cactttacag
    19381 atacagatgg tcaagagttt accatgattg atacggctgg tatgcgtaag tctggtaagg
    19441 tttatgaaaa tactgagaaa tactctgtta tgcgtgccat gcgtgctatt gaccgttcag
    19501 atgtggtctt gatggtcatc aatgcggaag aaggcattcg tgagtacgac aagcgtatcg
    19561 caggatttgc ccatgaagct ggtaaaggga tgattatcgt ggtcaacaag tgggatacgc
    19621 ttgaaaaaga taaccacact atgaaaaact gggaagaaga tatccgtgag cagttccaat
    19681 acctgcctta cgcaccgatt atctttgtat cagctttaac caagcaacgt ctccacaaac
    19741 ttcctgagat gattaagcaa atcagcgaaa gtcaaaatac acgtattcca tcagctgtct
    19801 tgaacgatgt catcatggat gccattgcca tcaacccaac accgacagac aaaggaaaac
    19861 gtctcaagat tttctatgcg acccaagtgg caaccaaacc accaaccttt gtcatctttg
    19921 tcaatgaaga agaactcatg cacttttctt acctgcgttt cttggaaaat caaatccgca
    19981 aggcctttgt ttttgaggga acaccgattc atctcatcgc aagaaaacgc aaataaaaaa
    20041 gtagaatctg gaatgacagt tccggatttt tttgatataa taaaataata gaaaacgcta
    20101 tcaaaagaag gagggtgatg tcggtgatgg aacatttgtt taaattctta cttttagcac
    20161 cgtactttta ttttgataac tggattgaga aggccaacag aaatagtaag ttttttccaa
    20221 ttttttatta tttttactgg ttttacatcc ccttctattc tctttttagc cttgcttgga
    20281 cagttgtttc agttctgttt ttcaataccg tcttgagaaa tgtgacagat atcaagttat
    20341 ggggcatttg gtttcttttt attctgctag ctattggtat gaattggtta acttattcct
    20401 gtttcaaaga aatgtttcgc ttgagacagg aactagggaa gtctaagggt ggaaggcatt
    20461 gatttatatc ggtttctatt tgtaggaggt ggcttatggt acctctaaaa tcatttatta
    20521 cacgctattc caaggtttat attggtaata acatttaata gaacgaaact aaagaaaaca
    20581 atttaaaaga ggaggtttgt gatggaatac ttgtttaaaa tgataatctt attaccctgt
    20641 ttttactttt tcagctggat tgaaaaggca aacagagata gtaagatttt cccaattttt
    20701 tactattttt actggattta catcaccctc tatgctcttt ttagccttgc ttggacagtt
    20761 ttttcagttc tgtttttcaa tatcgtcttg agaaatttga cagatatcaa gttatggggt
    20821 atttggctat tattactact tatcgctttt gctagtgact ggttagacta tatctgtttc
    20881 aaaaaaatgc ttgacttgag acgggaacta gggaagtcta aaggcggaag gcattgattt
    20941 atactcttcg aaaatctctt caaaccacgt caacgtcgcc ttggattata tatgtaactg
    21001 acttcgtcag tcttatctac aacctcaaag cagtgctttg agcaacttgc ggctagtttc
    21061 ctagtttgct ctttgatttt cattgagtat tatattactt tctatttgta ggaggtggct
    21121 tatgaagatt cctctcttaa ctttggcaag gcataaattt gtttatgtct tgcttacttt
    21181 gctttttctt gctttggttt atcgtgatgt tttgatgact tatttctttt ttgatattca
    21241 tgcgcccgat ctagctaaat tcgatggaca agcaattaaa aatgacttat taaaatcagc
    21301 attagatttt cgtattctcc agttcaatct aggtttttat caatcattta ttattccaat
    21361 catcattgtt ttgctaggtt ttcaatatat tgagctgaaa aataaagttt tacgattgag
    21421 tattggaaga gaagtgagct atcaagggtt aaaaagaaag ttgactttgc aagttgcaag
    21481 tatcccttgt ttgatatatt tagtgactgt gctgataatt gcaattataa cctatttctt
    21541 tgggactttt tctcctcttg aatggaattc tctattttct gatgggagtg gtttacaaag
    21601 actcctagat ggagagataa aaagctattt gttctttact tgtgtcctac taatcggtat
    21661 tttcatcaat gcaatctatt ttttacaaat agttgattat gtggggaatg tgactcgttc
    21721 ggcaatcacc tatttgatgt ttctttggct tggttctatg ctgctctata gtgccttgcc
    21781 ttactatatg gttcctatga cgagtttgat gcaagctagc tatggggatg taagtttgat
    21841 gaaactcttt actccttata tcctttatgt tgtcccttat atggtactta aaaaatatga
    21901 agataatgtt taagaatttt aacaatattt ggctaaagag aaagatcgtt ttactacttc
    21961 gtatagttct gatgatgatt ttgataaact atctattgtc aacagcggtt caaaagcagg
    22021 atgctgttat ctttttcaag agagaattga tttcaatttt ttcctataat gactattctg
    22081 aagcgaattt agaaatcccc aaactcttgt taaacctttc gcttttcatg gtaggatggc
    22141 tctctgtcat tttacttgaa agtgatttgg cagaccatta ccatcacttg attcgctatc
    22201 aatcaagctc ctttttcgat tatacaagga aacgattggt tgtcatttct aaatttttta
    22261 ctcaagattt gtttgtctgg tttcttggtt tacttccgct aggaattcat ttcaaaacag
    22321 tcgcactttt ctttttactt gctcagttaa tgatgttgta cttactactg tcttatctga
    22381 tagcactgat tagtgcgggc gctggttttt ctttttttct ctattttttg gcatttgtgg
    22441 gacaagaatg gatgatggat catattgtaa cagtgtattt agtactctta agcttattag
    22501 ttatgttgat tgttagtcgc ttggaagaga aatttaagaa aggataaacg atgagacttg
    22561 aaattataaa tggacagaaa atttatggga aaagacctat tttaaatcag ttgaatttgg
    22621 tgtttcaatc aggaaaaatt tatggactta aaggtgataa tggatctggc aagacggttc
    22681 ttttaaagat acttgctggt tatattaagc ttgacaaagg aaaagttctt caagatggta
    22741 aagtttacgg ggtaaaaaat cattatattc aggatgcagg aattttaatt gaaaaagtcg
    22801 agtttttatc tcatttatcc ctgagagaaa atttggaact gttaaggtat ttttcatcta
    22861 aagttacgga aaaaagaatt gcctattgga ttcaatacta tgatttacag gaatttgaag
    22921 acgttgaata ccgtcattta tccttgggaa caaagcaaaa aatggccttg attcaagcct
    22981 ttatttcctc tccttctata ctctttctcg atgaacctat gaatgctttg gatgagaaga
    23041 gtgtgaggtt aaccaaacag gtcattttat cttacctgaa aaaagaaaat ggtctggtta
    23101 tcctgacgtc gcacatatcg gaagatattt cagacctttg tacagatgta ttagttgtcg
    23161 aaaatggaca tatacaatat gtaaaggata tacaatccta ggagatggct tatggcacat
    23221 ctaaaatcat ttattacacg ctattccaag gtttatattg gtttagttct gctgatctgg
    23281 ctgtctttct tctttatccc ttgggataga gcgattctgg gggtaaggat tgacatcttc
    23341 atcatgcaga aaatcttgct agcttttgga attctgtcca ttctcatggc cttgctgtcc
    23401 aagaaagtca gtctctttgt ttttggactg atttgctgtc tttctctttg gattaactta
    23461 tttatcacat ttgccatttt gccgattttt ggcaattaaa cagtcataaa agtcggagag
    23521 gttagcttga aaactaacct ctttttcctt ttcaaaatgg ggattcttcc ttgaaaataa
    23581 tcagtaattg tgctaaaatt aaaggaacat tctaaaatat tcggaattta aagtaaggaa
    23641 aaacatggct aatattttaa aaacaattat cgaaaatgat aaaggagaaa tccgtcgtct
    23701 ggaaaagatg gctgacaagg ttttcaaata cgaagaccaa atggctactt tgactgacga
    23761 ccaactaaaa gcaaaaacag ttgaatttaa ggaacgttat caaaatggag aatcactgga
    23821 ttcattgctt tacgaagcat ttgcggttgt ccgtgaaggt gccaaacgtg tcctaggtct
    23881 cttcccttat aaggttcagg tcatgggggg gattgttctt caccatggtg acgtgccaga
    23941 gatgcgtaca ggggaaggga aaaccttgac tgcgaccatg ccggtatacc tcaatgccct
    24001 ttcaggtaaa ggggttcacg tagttacggt taatgaatac ctgtcagaac gtgacgcgac
    24061 tgagatgggt gaattgtact cttggcttgg tttgtcagta gggattaact tggctaccaa
    24121 atctccaatg gagaaaaaag aagcctatga gtgtgatatt acttactcaa ctaactcaga
    24181 aatcggattt gactaccttc gtgacaacat ggtcgttcgc gccgaaaaca tggtacaacg
    24241 tccgcttaac tatgccttgg tcgatgaggt tgactctatc ttgattgacg aggctcgtac
    24301 acctttgatt gtatcaggtg ccaatgcggt tgaaaccagt cagttgtatc acatggcaga
    24361 ccactatgta aaatctttga acaaagatga ctacatcatc gatgtgcagt ctaagactat
    24421 tggtttgtct gattcaggga ttgacagggc tgaaagctac ttcaaacttg aaaacctcta
    24481 tgacatcgaa aacgtggctt tgactcactt tatcgataac gcccttcgtg ccaactacat
    24541 catgcttctc gatattgact atgtggtgag cgaagagcaa gaaatcttga ttgtcgacca
    24601 atttacaggt cgtaccatgg aaggtcgtcg ttattctgat ggattgcacc aagctattga
    24661 agccaaagaa ggtgtgccaa tccaggatga aaccaagaca tctgcctcaa tcacgtacca
    24721 aaaccttttc cgtatgtaca agaaattgtc tggtatgacg ggtacaggta agactgagga
    24781 agaagaattc cgtgaaatct acaacattcg tgttattcca atcccaacaa accgtcctgt
    24841 tcaacgtatt gaccactcag accttcttta tgcaagtatc gaatctaagt ttaaagcggt
    24901 tgtcgaagac gttaaggctc gttaccaaaa gggtcaacct gtcttggttg gtacagtagc
    24961 ggttgaaact agtgactaca tttctaagaa attggttgca gctggtgttc ctcacgaagt
    25021 cttgaatgcc aaaaaccact atagagaagc ccaaatcatc atgaatgctg gtcaacgtgg
    25081 tgccgttacc atcgcaacca acatggcggg tcgtggtacc gacatcaagc ttggtgaagg
    25141 tgttcgtgaa cttggaggac tttgtgttat tggtacagaa cgtcatgaaa gtcgtcgtat
    25201 cgataaccag cttcgtggac gttcaggtcg tcaaggagat ccaggtgagt cacaattcta
    25261 cctatctctt gaagatgatt tgatgaaacg ttttggttct gaacgcttga agggaatctt
    25321 tgaacgtttg aacatgtctg aagaggcgat tgagtctcgc atgttgacgc gtcaggttga
    25381 agcagctcag aaacgtgtcg aaggaaataa ctacgatacc cgtaaacaag tccttcaata
    25441 cgatgatgtc atgcgtgaac aacgtgagat tatctatgct caacgttacg atgtcatcac
    25501 tgcagatcgt gacttggcac ctgaaattca ggctatgatc aaacgcacga ttgaacgtgt
    25561 cgttgatggt catgcgcgtg ccaaacaaga tgaaaaacta gaggcaattt tgaactttgc
    25621 taagtacaac ttgcttcctg aagattctat tacgatggaa gacttgtcag gcttgtctga
    25681 taaggccatc aaggaagagc ttttccaacg tgccttgaag gtttacgata gtcaggtttc
    25741 aaaactacgc gatgaagaag cagttaaaga attccaaaaa gttttgattc tacgagtggt
    25801 ggataacaag tggacagatc atatcgatgc ccttgatcaa ttgcgtaacg cggttggact
    25861 tcgtggctat gctcagaaca accctgttgt tgagtatcag gcagaaggtt tccgtatgtt
    25921 taatgatatg attggttcga ttgagtttga tgtgacacgc ttgatgatga aagcacaaat
    25981 tcatgaacaa gaaagaccac aggcagaacg tcatatcagt acaacagcga ctcgcaatat
    26041 cgctgctcac caagcaagta tgccagaaga tttggatttg agccagattg gacgcaatga
    26101 actttgccca tgtggttctg gtaagaaatt taaaaactgt cacggtaaaa gacaataaaa
    26161 tgagatagtt tagaggcgga tatcttgtga aaagtaaatt tttactgggt atccgtttgc
    26221 tttataagga gatgagttat ggtatttaca gcaaaaagct ctaaaataaa tatagaagaa
    26281 gttcgtgcct tgtcaaaatt agaaggtcag gctttggaga ggaaatcaca gcgcgatcaa
    26341 gagctagaag ccattatacg tggagaagat cagcgaattc tcttggtaat cgggccatgc
    26401 tcatctgaca acgaagaagc tgtccttgaa tacgctaagc gtttggcagt cctacaagaa
    26461 gaagtggcag atcgtatctt tatggttatg cgtgtttata ctgccaaacc ccgtaccaac
    26521 ggagatggct ataagggctt gattcaccag cctaacgcga cagaagcgcc tagtcttatc
    26581 aatggaatca aagccgttcg ccatcttcac tatcgtgtca tcacagaaac agggatgaca
    26641 actgctgatg aaatgcttta tcctgaaaac cttccgcttg tagatgattt gatttcttac
    26701 atggcagttg gtgcccgttc agttgaagac cagcaacacc gctttgtggc aagtggggca
    26761 ggattttcta ctggttttaa aaatccaacc tctggaaatc tcaatgtcat gtttaatggg
    26821 atttatgctg ctcaaaacaa acaaagtttc cttttcttag gaaaagaagt agaaacaact
    26881 gggaacccgc tttcacacgc tattcttcgt ggtgctctta atgagtatgg aaaaaatatt
    26941 cccaactact attatgacaa tttaattgat accattgccc aatatgagaa aatgggcttg
    27001 gaaaatcctt ttatcatcat tgataccaat catgacaatt ctggtaagca gtatattgaa
    27061 cagatccgaa ttgtccgcca gaccttgatt aaccgtgctt ggaatgaaaa aattaagcag
    27121 ttcgttcgtg gttttatgat tgagtcttat ctggaagatg gtcgacaaaa tgagccagaa
    27181 gtatttggca agtctatcac agacccttgc ctgggttggg ataacacaga agctcttgtc
    27241 agagaaattt acaaaacgtt aggagaataa gatggcattt attgaaaaag gtcaagaaat
    27301 cgatatggaa gtcatcaagg ctgaaaccca attgtctgcg gaagccttga gactcaagga
    27361 aagccgtgac agggaattgg cagatattat ttcaggggaa gatgaccgta ttctcttggt
    27421 gattggtcct tgctcttctg ataatgaaga ggcggtcttg gaatatgctc gccgtttatc
    27481 cgccttgcaa aagaaggtag cggacaagat tttcatggtc atgcgcgtgt atactgctaa
    27541 gcctcgtacc aatggagacg gctataaagg attggttcac cagccagata cttctaaggc
    27601 tccaagcctg attaacggtt tgcaggctgt gcgccagttg cattaccgcg tgattacaga
    27661 gactggtttg acaacggcag atgagatgct ttatccgtca aatctgatct tggtggatga
    27721 cttggtcagc taccatgccg ttggagctcg ttctgtggaa gaccaagagc accgctttgt
    27781 ggcttctggg attgatgcac cagtagggat gaaaaatcca acctcaggaa atttgggtgt
    27841 tatgtttaac gccatctatg ctgctcaaaa caagcaaacc ttcctttatc atgggcagga
    27901 agttgagaca tcaggtaatc ctttggccca tgttatcctc cgtggagcag tcaacgagta
    27961 tggcaattat atgccgaatt actactatga aaacctactc caagccattg aacgctatga
    28021 aaccatggga cttgaaaatc cttttatcct cattgacacc aaccatgata actcaggcaa
    28081 gcaatatatg gagcagattc gaattgttcg ccagaccttg cagaatcgtg attggaatga
    28141 gaaaattaaa aagacggttc gaggatttat gattgaatct tacctagcag atggtcgtca
    28201 aaaccaacca gagatctttg gttgctctat tactgaccct tgcctaggtt gggaaaatac
    28261 agaggccttg gtagaagaga tttatgttac cttgacaaaa taagtgaaaa ggatggagtt
    28321 ggggaatctc aactcctttt gatgagaatg atagttggac acggaattga catcgaagaa
    28381 ttggcttcga tagaaagcgc agttacacga catgaaggat ttgctaagcg tgtactgacc
    28441 gctcaggaaa tggagcgctt caccagtctc aaaggacgca ggcaaataga atatttagct
    28501 ggtcgctggt cggctaagga ggccttttcc aaggctatgg gaacgggcat tagcaagctc
    28561 ggttttcagg atttggaagt attgaacaat gaacgtgggg cgccttattt tagtcaggca
    28621 ccattttcag gaaagatttg gctgtctatc agccacaccg atcagtttgt gacagccagt
    28681 gtcattttgg aggaaaatca tgaaagctag tccacataga ccaaccaagg ctctgattca
    28741 tctgggagct attcgacaaa atattcagca aatgggggct catatccctc aaggaacgct
    28801 caagttggct gtggttaagg ccaatgctta tggtcatgga gctgttgccg ttgccaaggc
    28861 aattcaagat gatgttgatg gcttttgcgt ttccaatatc gatgaagcca ttgaactcag
    28921 acaagctgga ctcagcaagc caatcctcat tttaggagtt tctgaaatcg aagctgttgc
    28981 tctagctaaa gaatatgact tcaccttgac agtggctgga ctggagtgga ttcaagcact
    29041 cttagataag gaagtggacc taactggatt gacagtccac ctcaagattg attcagggat
    29101 gggacggatt ggttttagag aggcaagtga ggttgagcag gctcaagatt tgctccaaca
    29161 acacggtgtt cgtgttgaag gaatctttac ccactttgct actgctgatg aggaatcaga
    29221 tgactatttt aatgcccagt tagaacggtt taaaactatt ttagctagta tgaaggaagt
    29281 tccagagctg gttcatgcta gcaattctgc aacgactctt tggcatgtag agactatttt
    29341 caatgcggtt cgtatgggag atgccatgta tggtctcaat ccaagtggag cggtcttggc
    29401 tttgccttat gatttgatac cggccttgac cttggagtct gctctggttc atatcaagac
    29461 agttccagct ggtgcttgca tgggctatgg agcaacttat caaacggata gcgagcaagt
    29521 catcgcgacc gtgccaatcg ggtatgcaga tggatggaca agagacatgc aaaatttctc
    29581 tgtcttggta gatggccaag cttgcccaat tgtcggcagg gtttcgatgg accaaatcac
    29641 tattcgattg cctaagcctt acccactcgg aaccaaggta accttgattg gctccaatgg
    29701 ggataaggaa atcactgcaa ctcaggtagc gacctaccgc gtaaccatta actatgaggt
    29761 ggtttgcctc ctcagcgacc gtattccgag agaatattac tagaaaagaa aggagtggag
    29821 catgaatcta catcaaccct tgcatgtctt gcctggtgtg ggaccaaagt cagcagaaaa
    29881 atacgccaaa ctaggaattg aaaacttgca agatctcttg ctctactttc ctttccgtta
    29941 tgaagacttc aaaatcaagc aggtgctgga gctggaagac ggtgagaagg cagttctttc
    30001 tggtcaggta gtgactcctg ctagtgtcca gtattatggt ttcaagcgca atcgcctgcg
    30061 ttttagtctc aagcagggag aggtcgtttt tgcggtgaat ttctttaacc agccctatct
    30121 ggctgataaa atagagttgg gagcaaccct tgctgtcttt ggaaaatggg accgcgctaa
    30181 ggctagtctg actgggatga aggttctggc tcaggtagaa gatgacctcc agcctgtcta
    30241 tcgtctggct cagggaatca gtcaggccag tctggttaag gtcatcaaga cggcttttga
    30301 tcagggactg gacctcttga tagaagaaaa tctgccccag tctttactag acaaatacaa
    30361 actcatgtcc cgttgtcagg cagtccgagc tatgcatttt ccaaaggatt tggcagaata
    30421 caagcaggct cttcgccgta tcaagtttga ggaactcttt tatttccaaa tgcagctgca
    30481 gatgctcaag tctgaaaata gagttcaggg aagtggtctg gttctgaatt ggtctcagga
    30541 aaaagtgaca gcagttaaag taagtcttcc ttttgccctg acccaagctc aggaaaagag
    30601 tttgcaggaa attttaactg atatgaagtc cgaccaccac atgaatcgtc tcctacaagg
    30661 ggatgtgggg agtggaaaaa cggtagtcgc tggcttggcc atgtttgcgg cagtgacagc
    30721 aggttatcag gctgccctaa tggtaccaac agaaatcctc gcagagcaac actttgagag
    30781 tttacagaac ctttttccca atttgaaact ggctctcttg acaggttcct tgaaagctgc
    30841 agaaaagaga gaggtcttgg agaccattgc caagggtgag gctgatttga ttatcggaac
    30901 tcacgctctg atacaagatg gggtggagta tgctcgtctt ggtttgatta ttatcgatga
    30961 gcagcaccgt tttggtgtag ggcaaaggcg tattttacgg gaaaaaggtg acaatccaga
    31021 tgtcctcatg atgacggcga ctcccattcc acggacgctt gccatcacag cctttggaga
    31081 tatggatgtt tccattatcg accagatgcc agcaggtcgg aagcctattg tgacgcgctg
    31141 gatcaaacat gagcaactac ctcaggtctt gacttggtta gagggggaaa ttcaaaaagg
    31201 ttcccaagcc tatgtcatct ctcctttgat tgaagaatca gaagctctag atttgaaaaa
    31261 tgccattgcc ttatcagagg agttgacgac tcattttgca ggcaaggcag aggtggctct
    31321 tctacatggt aggatgaaga gtgacgaaaa agaccagatc atgcaggatt tcaaggagag
    31381 aaagacggat attctggttt cgacgacggt tattgaggtt ggggtcaacg ttcccaatgc
    31441 gactgtcatg attatcatgg atgccgatcg cttcggtctc agtcaacttc accagcttag
    31501 aggtcgtgtc ggtcgggggg acaagcagtc ctacgctgtt ctcgttgcca atcccaagac
    31561 ggattctggg aaagaccgca tgcgtatcat gacagaaacg accaatggat ttgtccttgc
    31621 ggaggaagat ttgaaaatgc gtggttctgg tgagattttt ggaaccagac agtcaggact
    31681 tccagagttc caagtggctg atattatcga agattttccg attttagaag aagcaagaaa
    31741 ggttgctagc tacattagtt ctatagaagc ttggcaagaa gatccagagt ggcgcatgat
    31801 tgcccttcat ctggaaaaga aagaacatct ggattaagct ttctctaagg aaaacttaag
    31861 ctagttttta ggtttggctc ttatactaaa gtcatcaaaa agaaacgagg actctcatat
    31921 gacagtaacg attaaagtaa attaccaaac cactttccaa aagaaggaag caaaaaacta
    31981 gtataaacag aagagagagc gaaatgctct ttttcgtttc taaaactact ttcagcccat
    32041 catcctaaaa gtaaagaatc taaattcact ttctatttat ccttctttct tgcattgatt
    32101 acatagatat gctacagttg tggtaacgat tacaaaataa aaggagcatg ctatgaaaaa
    32161 tccagctttg ctagaagaaa ttaagaccta tagaggaagg gatgaggttc cggaagactt
    32221 tgatgctttc tgggatgggg aagtgaaaaa tgtttccacg cttccatcct accacttgga
    32281 ggaaagagat ttccacattc ctcaagtcaa gtgctatgag ttaacatttg aaggaagcaa
    32341 ggaaggaaag gtctatgcac gcattgttct tccaaagagt gaggagaagg ttccactaat
    32401 cttccatttt catggttata tgggacgtgg ctgggactgg gccgacatgc tgggcttcac
    32461 cgtagctggt tacggtgttg tttccatgga tgtgcggggc cagtcaggtt actcacaaga
    32521 cggcttgcgt tctcctttag gaaataccgt gaaggggcat attatccgtg gtgctatgga
    32581 aggtcgggac cacctctttt ataaggatgt ttatctggat atttaccagt tggtcgaaat
    32641 tgttgctagt ctgtctcagg ttgatgagaa gcgtctttct agctatggtg cctcacaagg
    32701 aggggctcta gctctagttg cagcagcgct caatcctcga attcagaaaa cagttgccat
    32761 ttatcccttc ttgtcagact tcagacgggt gattgagatt ggtaatacta gcgaggctta
    32821 cgacgaactt ttccgttatt tcaagtttca cgaccccttc catgaaacag aggaggaaat
    32881 catggcgacc cttgcctata tcgatgtcaa aaatcttgcc catcgtatcc aaggtgaggt
    32941 taagatgatt acgggcttgg acgacgatgt ttgctatccc attacccagt ttgcgattta
    33001 taatcgtctg acctgcgata aaacctatcg catcatgcct gagtatgctc acgaagccat
    33061 gaatgtattt gtcaatgacc aagtctacaa ctggctctgt ggaagtgaga ttccttttaa
    33121 atatctaaaa taaggagtcg actctaagca caaaatctta aaaattacaa acacgcatag
    33181 tatcagggga ttaaaaaaac ttgatactat gcgttttatc atggaaatat agtaaaatga
    33241 aacaagaata ggacaaaacg atcaggacag tcaaatcgat ttctaacaat gttttagaag
    33301 caaatgtgta ctattctagt ttcaatctat tatatttata gaattttttg ttgctagatt
    33361 tgtcaaattg cttaaaataa tttttttcag aaagcaaaag ccgataccta tcgagtaggg
    33421 tagttcttgc tatcgtcagg cttgtctgta ggtgttaata cttttcaaaa atctctttaa
    33481 accacgtcag cttcgccttg ccgtatatat gttactgact tcgtcagttc tatctgccac
    33541 ctcaaaacgg tgttttgagc tgactttgtc agtcttatct acaacctcaa aacagtgttt
    33601 tgagcatcat gcggctagct tcttagtttg ctctttgatt ttcattgagt ataaaaacag
    33661 atgagtttct gttttctttt tatggactat aaatgttcag ctgaaactac tttcaaggac
    33721 attattatat aaaagaattt tttgaaacta aaatctacta tattacacta tattgaaagc
    33781 gttttaaaaa tgaggtataa taaatttact aacgcttata aaaagtgata gaatctatct
    33841 ttatgtatat ttaaagatag attgctgtaa aaatagtagt agctatgcga aataacagat
    33901 agagagaagg gattgaagct tagaaaaggg gaataatatg atatttaagg cattcaagac
    33961 aaaaaagcag agaaaaagac aagttgaact acttttgaca gtttttttcg acagttttct
    34021 gattgattta tttcttcact tatttgggat tgtccccttt aagctggata agattctgat
    34081 tgtgagcttg attatatttc ccattatttc tacaagtatt tatgcttatg aaaagctatt
    34141 tgaaaaagtg ttcgataagg attgagcagg aagtatggta taaatagcat aagctgatgt
    34201 ccatcatttg cttataaaga gatattttag tttaattgca gcggtgtcct ggtagataaa
    34261 ctagattggc aggagtctga ttggagaaag gagaggggaa aattggcacc aatttgagat
    34321 agtttgttta gttcattttt gtcatttaaa tgaactgtag taaaagaaag ttaataaaag
    34381 acaaactaag tgcattttct ggagtaaatg tcttatttca gaaatcggga tatagatata
    34441 gagaggatca gtatgaatcg gagtgttcaa gaacgtaagt gtcgttatag cattaggaaa
    34501 ctatcggtag gagcggtttc tatgattgta ggagcagtgg tatttggaac gtctcctgtt
    34561 ttagctcaag aaggggcaag tgagcaacct ctggcaaatg aaactcaact ttcgggggag
    34621 agctcaaccc taactgatac agaaaagagc cagccttctt cagagactga actttctggc
    34681 aataagcaag aacaagaaag gaaagataag caagaagaaa aaattccaag agattactat
    34741 gcacgagatt tggaaaatgt cgaaacagtg atagaaaaag aagatgttga aaccaatgct
    34801 tcaaatggtc agagagttga tttatcaagt gaactagata aactaaagaa acttgaaaac
    34861 gcaacagttc acatggagtt taagccagat gccaaggctc cagcattcta taatctcttt
    34921 tctgtgtcaa gtgctactaa aaaagatgag tacttcacta tggcagttta caataatact
    34981 gctactctag aggggcgtgg ttcggatggg aaacagtttt acaataatta caacgatgca
    35041 cccttaaaag ttaaaccagg tcagtggaat tctgtgactt tcacagttga aaaaccgaca
    35101 gcagaattgc caaatggtcg agttcgcctg tatgttaatg gtgttttatc tcgaacaagt
    35161 ctgaaatctg gcaatttcat taaagatatg ccagatgtaa cgcatgtgca aatcggagca
    35221 accaagcgtg ccaacaatac ggtttggggg tcaaatctac agattcggaa tctcactgtg
    35281 tataatcgtg ctttaacacc agaagaggta caaaaacgta gtcaactttt taaacgctca
    35341 gatttagaaa aaaaactacc tgaaggagcg gctttaacag agaaaacgga catattcgaa
    35401 agcgggcgta acggtaaacc aaataaagat ggaatcaaga gttatcgtat tccagcactt
    35461 ctcaagacag ataaaggaac tttgatcgca ggtgcagatg aacgccgtct ccattcgagt
    35521 gactggggtg atatcggtat ggtcatcaga cgtagtgaag ataatggtaa aacttggggt
    35581 aaccgagtaa ccattaccaa cttacgtgac aatccaaaag cttctgaccc atcgatcggt
    35641 tcaccagtga atatcgatat ggtgttggtt caagatcctg aaaccaaacg aatcttttct
    35701 atctatgaca tgttcccaga agggaaggga atctttggaa tgtcttcaca aaaagaagaa
    35761 gcctacaaaa aaatcgatgg aaaaacctat caaatcctct atcgtgaagg agaaaaggga
    35821 gcttatacca ttcgagaaaa tggtactgtc tatacaccag atggtaaggc gacagactat
    35881 cgcgttgttg tagatcctgt taaaccagcc tatagcgaca agggtgatct atacaagggt
    35941 aaccaattac taggcaatat ctacttcaca acaaacaaaa cttctccatt tagaattgcc
    36001 aaggatagct atctatggat gtcctacagt gatgacgacg ggaagacatg gtcagcgcct
    36061 caagatatta ctccgatggt caaagccgat tggatgaaat tcttgggtgt aggtcctgga
    36121 acaggaattg tacttcggaa tgggcctcac aagggacgga ttttgatacc ggtttatacg
    36181 actaataatg tatctcactt aaatggctcg caatcttctc gtgtcatcta ttcagatgat
    36241 catggaaaaa cttggcatgc tggagaagcg gtcaacgata accgtcaggt agacggtcaa
    36301 aagatccact cttctacgat gaacaataga cgtgcgcaaa atacagaatc aacggtggta
    36361 caactaaaca atggagatgt taaactcttt atgcgtggtt tgactggaga tcttcaggtt
    36421 gctacaagta aagacggagg agtgacttgg gagaaggata tcaaacgtta tccacaggtt
    36481 aaagatgtct atgttcaaat gtctgctatc catacgatgc ataatggaaa agaatacatt
    36541 atcctcagca atgcaggtgg accgaatcgt gaaaatggga tggtccactt ggcacgtgtc
    36601 gaagaaaatg gtgagttgac ttggctcaaa cacaatccaa ttcaaaaagg agagtttgcc
    36661 tataattcgc tccaagaatt aggaaatggg gagtatggca tcttgtatga acatactgaa
    36721 aaaggacaaa atgcctatac cctatcattt agaaaattta attgggaatt tttgagcaaa
    36781 gatctgattt ctcctaccga agcgaaagtg aagcgaacta gagagatggg caaaggagag
    36841 atgggcaaag gagttattgg cttggagttt gactcagaag tattggtcaa caaggctcca
    36901 acccttcaat tggcaaatgg taaaacagcg actttcctaa cccagtatga tagcaaaacc
    36961 ttgttgtttg cagtagataa ggaagatatc ggacaggaaa ttattggtat agctaaagga
    37021 agcatcgaaa gtatgcataa tcttcctgta aatctagcag gtgccagagt tcctggcgga
    37081 gtaaatggta gcaaagcagc ggtgcatgaa gttccagaat ttacaggggg agttaatggt
    37141 acagagccag ctgttcatga aatcgcagag tataagggat ctgattcgct tgtaactctt
    37201 actacaaaag aagattatac ttacaaagct cctcttgctc agcaggcact tcctgaaaca
    37261 ggaaacaagg agagtgacct cctagcttca ctaggactaa cagctttctt ccttggtctg
    37321 tttacgctag ggaaaaagag agaacaataa gagaagaatt ctaaacattt gattttgtaa
    37381 aaatagaagg agatagcagg ttttcaagcc tgctatcttt ttttgatgac attcaggctg
    37441 atacgaaatc ataagaggtc tgaaactact ttcagagtag tctgttctat aaaatatagt
    37501 agattgaaat aagatgtgaa caactctatc aggaaagtca aattaattta tagaaaaatt
    37561 ttagcagtca aggtgtactg ttatagattc aatatattat gtgactatta accttctctt
    37621 ctcctaaaat tgactttctt gttttcttat cttgtccact cgaaacaagt attgtaagaa
    37681 tttgattatt tttgaaagta cttttaatat acttgatata gttaaaaaag atttgaaact
    37741 aaattccaaa ttagaaaaag acttgaaata ctaaaaaaaa aaagtatact ctaattgaaa
    37801 acggtaacaa aactaattta gagaatgaaa tatagagtat ttctctctta aaagtttttg
    37861 gtgaaacgag atgtagaaag gagatttagc caaagagtct attagtgcta gaataataga
    37921 ttagaattat tttagaaaaa cgaagtgagc agcttataaa ttcaagtccc caaatagatt
    37981 catactagta tcttttgcaa aaaataaagg gcgacttcct tcatgaatat caatttcatc
    38041 tataaggaag gtagctaatt gaactaactt atttattctg tttgtcgcta gaaaaatcag
    38101 acctccttgt gaagattgag gagatactga atgaaaatca aagaagaaac tagcaagcta
    38161 gtagcagatt gcccaaaaca ccgccttgag gttgtagata agactgacct atataatcca
    38221 aggtgaagcg actgtggttt gaagagattt tcaaagagta taggctagag agtagtgttt
    38281 ttatgtcctt ctagtagaaa atgctagaca gaagaatggg gaacttggat aggaaaaata
    38341 gattgagaaa ggaggttaga agagatgatt attacaaaaa ttagccattt aggaacttat
    38401 gtgggagtaa atccacattt tgcaacatta atagattttc tagaaaaaac aggactagaa
    38461 aatttaacag aaggttcgat tgctatcgat ggtaatcgat tgtttgggaa ttgctttact
    38521 tatctagcag atggtcaagc aggggctttc tttgaaacac accaaaaata tttggatatt
    38581 catttagttt tggaaaacga agaagccatg gctgttacat cgccggaaaa tgtaagcgtt
    38641 acccaagaat atgatgaaga gaaagatatt gaattataca cagggaaagt ggaacagttg
    38701 gttcagttga gagctggcga atgcctcatc acttttccag aagatttaca tcaacccaag
    38761 gttcgtataa atgatgaacc tgtgaaaaaa gttgtcttta aagttgcgat ttcttaatgt
    38821 agaaagagaa gaacgatgaa aaaaatgaga aagtttttat gtctagctgg aattgcgcta
    38881 gcggctgttg ccttggtagc ttgttcagga aaaaaagaag ctacaactag tactgaacca
    38941 ccaacagaat tatctggtga gattacaatg tggcactcct ttactcaagg accccgttta
    39001 gaaagtattc aaaaatcagc agatgctttc atgcaaaagc atccaaaaac gaaaatcaag
    39061 attgaaacat tttcttggaa tgacttctat actaaatgga ctacaggttt agcaaatgga
    39121 aatgtgccag atatcagtac agctcttcct aaccaagtaa tggaaatggt caactcagat
    39181 gctttggttc cgctaaatga ttctatcaag cgtattggac aagataaatt taacgaaact
    39241 gccttaaatg aagcaaaaat cggagatgat tactactctg ttcctcttta ttcacatgca
    39301 caagtcatgt gggttagaac agatttgtta aaagaacata atattgaggt tcctaaaact
    39361 tgggatcaac tctatgaagc ttctaaaaaa ttgaaagaag ctggagttta tggcttgtct
    39421 gttccgtttg gaacaaatga cttaatggca acacgtttct tgaacttcta cgtacgtagt
    39481 ggtggaggaa gcctcttaac aaaagatctt aaagcagact tgacaagcca acttgctcaa
    39541 gatggtatta aatactgggt taaattgtat aaagaaatct cacctcaaga ttctttgaac
    39601 tttaatgtcc ttcaacaagc taccttgttc tatcaaggaa aaacagcatt tgactttaac
    39661 tctggcttcc atatcggagg aattaatgcc aacagtcctc aattgattga ttcgattgat
    39721 gcttatccta ttccaaaaat caaagagtct gataaagacc aaggaattga aacctcaaac
    39781 attccaatgg ttgtttggaa aaattcaaaa catccagaag ttgctaaagc attcttagaa
    39841 gcactttata atgaagaaga ctacgttaaa ttccttgatt caactccagt aggtatgttg
    39901 ccaactatta aggggattag cgattctgca gcctataaag aaaatgaaac tcgtaagaag
    39961 tttaaacatg ctgaagaagt aattactgaa gctgttaaaa aaggtactgc tattggttat
    40021 gaaaatggac caagtgtaca agctggtatg ttgactaacc aacacattat tgaacaaatg
    40081 ttccaagata tcattacaaa tggaacagat cctatgaaag cagcaaaaga agcagaaaaa
    40141 caattaaacg atttatttga ggctgttcag tagatgtaaa agactagaaa ataggtgggc
    40201 tagtgagctg aaaagctcta gcccaatctt gtaaaagaag ggagaaggag aatggttaaa
    40261 gaacgtaatt taactcgctg gatatttgtt ttgccagcta tgattatcgt aggattactc
    40321 tttgtttatc cgtttttctc gagtattttt tatagcttta ccaataagca tttgattatg
    40381 cctaattata aatttgttgg tttggctaac tataaagctg tgctatcaga tcccaacttc
    40441 tttaatgcgt tctttaattc aattaagtgg accgttttct cattagttgg tcaagtttta
    40501 gtagggtttg tattggcttt agctcttcac agagtacgcc acttcaagaa attatatagg
    40561 accttattga ttgttccttg ggcatttcct accatcgtta ttgccttttc ttggcagtgg
    40621 attctaaacg gggtttatgg ctacttacct aatctaatcg taaaattagg tttaatggaa
    40681 catacacctg catttttgac agatagtaca tgggcattcc tatgtttggt gtttatcaac
    40741 atttggtttg gagcaccaat gattatggtt aatgtgcttt cagctttgca aacagtacca
    40801 gaagaacaat ttgaggctgc taagatagat ggtgcttcaa gttggcaggt gttcaagttt
    40861 atcgtctttc cacatattaa agtggttgta ggacttctag ttgttttgag aactgtatgg
    40921 atctttaata actttgacat tatctacctc attactggtg gtggaccagc caatgctaca
    40981 acgacgcttc caatttttgc ttacaacctg ggctggggaa ctaaattgtt gggtcgtgct
    41041 tcagcagtta cagtattgct ctttatcttc ttggtggcga tttgctttat ctactttgct
    41101 atcatcagta agtgggaaaa ggagggtaga aaataatgaa gaagaaatcc agtatttatt
    41161 tagatattct ctcacatgta cttttagttg gtgcgaccat cgttgcaatt ttcccattgg
    41221 tatggattat catatcttct gtcaaaggga aaggggaatt aactcagtat ccaacacgat
    41281 tttggcctga acagtttaca ttagattatt tcactcatgt tatcaacgat ttgcacttca
    41341 ttgataacat tcgaaacagt ttaatcattg ccttggctac aaccctcatt gcgattatta
    41401 tttctgctat ggcagcctat ggtattgttc gattctttcc taaattggga gcaatcatgt
    41461 cgagactact cgtcattacc tacattttcc caccaatttt gttagcaatt ccctattcaa
    41521 ttgccattgc taaagttggg ttaacaaata gtttatttgg cttgatgatg gtttatctat
    41581 cttttagtgt tccatatgca gtttggctct tagttggatt tttccaaaca gttccaattg
    41641 gaattgaaga agcggctaga attgatggtg caaataaatt tgttacgttt tataaagttg
    41701 tgctaccgat tgtagcacca ggtattgtag caacagctat ttatacattt atcaatgctt
    41761 ggaatgaatt cctgtatgcc ttgattttga ttaacaatac aggaaagatg acagtagcag
    41821 tagcccttcg ttcacttaat ggttcagaaa tactagactg gggagatatg atggcagcgt
    41881 ctgttattgt agttcttcca tcaattattt tcttctctat catccaaaat aagattgcaa
    41941 gtggattatc agaaggatct gtgaagtaga cgaaagaagg aaaaaaatga ataaaagagg
    42001 tctttattca aaactaggaa tttctgttgt aggcattagt cttttaatgg gagtccccac
    42061 tttgattcat gcgaatgaat taaactatgg tcaactgtcc atatctccta tttttcaagg
    42121 aggctcatat caactgaaca ataagagtat agatatcagc cctttgttat tagataaatt
    42181 gtctggagag agtcagacag tagtaatgaa atttaaagca gatgaaccaa actctcttca
    42241 agctttgttt ggcctatcta atagtaaagc aggctttaaa aataattact tttcaatttt
    42301 catgagagat tctggtgaga taggtgtaga aataagagac gcccaaaagg gaataaatta
    42361 tttattttcc agaccagctt cattatgggg aaaacataaa ggacaggcag ttgaaaatac
    42421 actagtattt gtatctgatt ctaaagataa aacatacaca atgtatgtta atggaataga
    42481 agtgttctct gaaacagttg atacattttt gccaatttca aatataaatg gtatagataa
    42541 ggcaacacta ggagctgtta atcgtgaagg caaggaacat tacctcgcaa aaagaagtat
    42601 tgatgaaatc agtctattta acaaagcaat tagtgatcag gaagtttcaa atattccctt
    42661 gtcaaatcca tttcagttaa ttttccaatc aggagattct actcaagcta actattttag
    42721 aataccgaca ctatatacat taagtagtgg aagagttcta tcaagtattg atgcacgtta
    42781 tggtgggact catgattcta aaagtaagat taatattgcc acttcttata gtgatgataa
    42841 tgggaaaacg tggagtgagc caatttttgc tatgaagttt aatgactatg aggagcagtt
    42901 agtttactgg ccacgagata ataaattaaa gaatagtcaa attagtggaa gtgcttcatt
    42961 catagattca tccattgttg aagataaaaa atctgggaaa acgatattac tagctgatgt
    43021 tatgcctgcg ggtattggaa ataataatgc aaataaagcc gactcaggtt ttaaagaaat
    43081 aaatggtcat tattatttaa aactaaagaa gaatggagat aacgatttcc gttatacagt
    43141 tagagaaaat ggtgtcgttt atgatgaaac aactaataaa cctacaaatt atactataaa
    43201 tgataagtat gaagttttgg agggaggaaa gtctttaaca gtcgaacaat attcggttga
    43261 ttttgatagt ggctctttaa gagaaaggca taatggaaaa caggttccta tgaatgtttt
    43321 ctacaaagat tcgttattta aagtgactcc tactaattat atagcaatga caactagtca
    43381 gaatagagaa gagagttggg aacaatttaa gttgttgcct ccgttcttag gagaaaaaca
    43441 taatggaact tacttgtgtc ctggacaagg tttagcatta aaatcaagta acagattgat
    43501 ttttgcaaca tatactagtg gagaactaac ctatctcatt tctgatgata gtggtcaaac
    43561 atggaagaaa tcctcagctt caattccgtt taaaaatgca acagcagaag cacaaatggt
    43621 tgaactgaga gatggtgtga ttagaacatt ctttagaacc actacaggta agatagctta
    43681 tatgactagt agagattctg gagaaacatg gtcggaagtt tcgtatattg atggaatcca
    43741 acaaacttca tatggcacac aagtatctgc aattaaatac tctcaattaa ttgatggaaa
    43801 agaagcagtc attttgagta caccaaattc tagaagtggc cgtaagggag gtcaattagt
    43861 tgtcggttta gtcaataaag aagatgatag tattgattgg aaataccact atgatattga
    43921 tttgccttcg tatggttatg cctattctgc gattacagaa ttgccaaatc atcacatagg
    43981 tgtactgttt gaaaaatatg attcgtggtc gagaaatgaa ttgcatttaa gcaatgtagt
    44041 tcagtatata gatttggaaa ttaatgattt aacaaaataa aggagaaaaa catggttaaa
    44101 tacggtgttg ttggagcagg gtattttgga gctgaattgg ctcgctacat gcaaaagaat
    44161 gatggagcag agattactct tctctatgat ccagataatg cagaggcgat tgcagaagaa
    44221 ttgggagcaa aagtagcaag ttccttagat gagttggttt ctagcgatga agtagattgt
    44281 gttatcgtcg caactccaaa taatcttcat aaggaaccgg ttattaaggc tgcacagcat
    44341 ggtaaaaatg ttttctgtga aaaaccaatt gcgctttctt atcaagattg tcgcgagatg
    44401 gtagatgcgt gtaaagaaaa caatgtaacc tttatggcag gacatattat gaatttcttt
    44461 aatggtgttc atcatgcaaa agaactcatt aatcaaggag ttatcggaga cgttctatat
    44521 tgtcatacag ctcgtaatgg ttgggaagaa caacaaccgt cagtgtcatg gaaaaaaatt
    44581 cgtgaaaaat caggtggtca cttgtatcac cacatccatg aattggattg cgttcaattc
    44641 cttatggggg gcatgcctga aactgtaacc atgacaggtg gaaatgtggc ccatgaaggt
    44701 gaacatttcg gtgatgaaga tgatatgatt tttgtcaata tggaattttc taataagcgt
    44761 tttgccttgt tagaatgggg ttcagcttat cgttggggtg aacattatgt cttaatccaa
    44821 ggaagcaaag gtgccatccg cttagactta ttcaactgta aaggaactct taagctagat
    44881 gggcaagaaa gctatttctt gattcacgaa tcgcaagaag aagatgatga tcggactcgt
    44941 atctatcata gtacagagat ggatggagca attgcttatg gtaaaccagg taaacgtact
    45001 ccattatggc tatcatctgt cattgataaa gaaatgcgct atctgcatga gattatggaa
    45061 ggagctccag tatcagaaga atttgcaaaa cttttgacag gtgaagctgc cctagaagca
    45121 attgctactg cagatgcttg tacccagtct atgtttgaag atcgcaaagt aaaattgtca
    45181 gaaattgtaa aataaatttt ggtattctcc tatttatagg tcgacttgct cctctgaaag
    45241 tacttttaga ggagctgttt gactttgcta gtttttgaaa ctgaaatcta ttatactaca
    45301 aactattgaa agcgttttaa ttttaaggta taataatctc atagaaataa agaaaaggag
    45361 gaaagaggat gccacagatt agcaaagaag ccttgattga gcaaatcaaa gatggaatca
    45421 tcgtttcttg tcaggctctt cctcatgaac cgctttatac agaagcggga ggggtgattc
    45481 ccttgctggt caaagcggct gagcaaggtg gagcagtcgg tatccgagca aacagtgttc
    45541 gcgatatcaa ggaaattaag gaagtcacta aacttccaat cattgggatt atcaaacgtg
    45601 attatccacc tcaggaaccc ttcatcacgg ctactatgaa agaagttgat gaattggcag
    45661 aactggacat cgaggtgatt gctctggatt gtaccaagcg tgaacgctac gatggtttgg
    45721 aaattcaaga gttcattcgt caggttaagg agaaatatcc taatcagctt ttgatggctg
    45781 atactagtat cttcgaagaa gggctagcag ctgtagaagc aggaattgac tttgtcggaa
    45841 caaccttatc aggctacaca tcctacagtc caaaagtaga cggtccagat tttgaattga
    45901 ttaagaaact ctgtgatgcc ggtgtagatg tcattgcaga aggaaaaatt catacaccag
    45961 aacaagccaa acaaatcctt gaatatggag tgcgaggcat cgttgttggt ggcgccatta
    46021 ctagaccaaa agagattaca gaacgcttcg ttgctagtct taaataagat gtgaggggga
    46081 gttttatgtt taaagtttta caaaaagttg gaaaagcttt tatgttacct atagctatac
    46141 ttcctgcagc aggtctactt ttggggattg gtggtgcact ttcaaaccca accacgatag
    46201 caacttatcc aatactagac aatagtattt ttcaatcaat attccaagta atgagctctg
    46261 caggagaggt tgtattcagt aatttgtcac tacttctctg tgtgggatta tgtattggct
    46321 tagcgaaacg agataaagga accgctgcgt tagcaggagt aactggttac ttagttatga
    46381 ctgcaacgat caaagcttta gtaaaacttt ttatggcaga aggatctgca attgatactg
    46441 gagttattgg agcattagtt gtcggaatag ttgccgtata tttgcacaac cgatataaca
    46501 atattcaatt accttccgct ttaggattct ttggaggttc acgcttcgtt cctattgtta
    46561 catcgttctc ttctatcttg attggctttg tcttctttgt tatttggcca cctttccaac
    46621 aacttcttgt ttctacaggt ggatatattt ctcaggcggg tccaattgga acttttctat
    46681 atggattttt aatgagactt tctggagcag taggcttaca tcatataatt taccctatgt
    46741 tttggtatac tgaacttggt ggtgttgaaa ctgttgcagg acaaacagtg gttggagctc
    46801 aaaaaatatt ttttgctcaa ttagccgatt tggcccattc tggattattt acagaaggaa
    46861 caaggttttt tgcaggtcgt ttctcaacaa tgatgttcgg tttaccggct gcctgtttag
    46921 cgatgtacca tagtgttcct aaaaatcgtc gtaaaaaata cgcgggtttg tttttgggag
    46981 ttgctttaac atcttttatt accggtatta cagaaccaat tgaatttatg tttctattcg
    47041 ttagtccggt tctatatgtt gttcacgcat tccttgatgg tgttagcttc tttattgcag
    47101 acgtcttaaa tatttcaata ggaaacacat tttcaggagg tgtaatcgat ttcactttat
    47161 ttggaatttt gcaggggaac gctaagacga attgggttct tcagattcca tttggactta
    47221 tttggagtgt tttgtattat attattttta gatggttcat tactcaattc aacgttctaa
    47281 cgccagggcg aggagaagaa gtagattcta aagaaatttc tgaatccgca gattcaactt
    47341 caaatactgc agattattta aaacaggata gcctacaaat tatcagagcc ttgggtggat
    47401 caaataatat agaagatgta gatgcttgtg tgacacgttt acgtgtagct gtaaaagaag
    47461 ttaatcaagt tgataaagca cttttaaaac aaattggtgc agttgatgtc ttagaagtga
    47521 agggtggcat tcaagcaata tatggagcaa aagcaatctt atataaaaat agtattaatg
    47581 aaattttagg tgtagatgat taagtactta ctgacttaat aaaaaacaga ggagagtgat
    47641 ggatgagtag gatgaaatga aatcgcatac aagaaataaa gaactcatta tccaagttgg
    47701 atacgcttat tacataggag aatacaaatg aaatttagaa aattagcttg tacagtactt
    47761 gcgggtgctg cggttcttgg tcttgctgct tgtggcaatt ctggcggaag taaagatgct
    47821 gccaaatcag gtggtgacgg tgccaaaaca gaaatcactt ggtgggcatt cccagtattt
    47881 acccaagaaa aaactggtga cggtgttgga acttatgaaa aatcaatcat cgaagcgttt
    47941 gaaaaagcaa acccagatat aaaagtgaaa ttggaaacca tcgacttcaa gtcaggtcct
    48001 gaaaaaatca caacagccat cgaagcagga acagctccag acgtactctt tgatgcacca
    48061 ggacgtatca tccaatacgg taaaaacggt aaattggctg agttgaacga cctcttcaca
    48121 gatgaatttg ttaaagatgt caacaatgaa aacatcgtac aagcaagtaa agctggagac
    48181 aaggcttata tgtatccgat tagttctgcc ccattctaca tggcaatgaa caagaaaatg
    48241 ttagaagatg ctggagtagc aaaccttgta aaagaaggtt ggacaactga tgattttgaa
    48301 aaagtattga aagcacttaa agacaagggt tacacaccag gttcattgtt cagttctggt
    48361 caagggggag accaaggaac acgtgccttt atctctaacc tttatagcgg ttctgtaaca
    48421 gatgaaaaag ttagcaaata tacaactgat gatcctaaat tcgtcaaagg tcttgaaaaa
    48481 gcaactagct ggattaaaga caatttgatc aataatggtt cacaatttga cggtggggca
    48541 gatatccaaa actttgccaa cggtcaaaca tcttacacaa tcctttgggc accagctcaa
    48601 aatggtatcc aagctaaact tttagaagca agtaaggtag aagtggtaga agtaccattc
    48661 ccatcagacg aaggtaagcc agctcttgaa taccttgtaa acggatttgc agtattcaac
    48721 aataaagacg acaagaaagt cgctgcatct aagaaattca tccagtttat cgcagatgac
    48781 aaagagtggg gacctaaaga cgtagttcgt acaggtgctt tcccagtccg tacttcattt
    48841 ggaaaacttt atgaagacaa acgcatggaa acaatcagcg gctggactca atactactca
    48901 ccatactaca acactattga tggttttgct gaaatgagaa cactttggtt cccaatgttg
    48961 caatctgtat caaatggtga cgaaaaacca gcggatgctt tgaaagcctt cactgaaaaa
    49021 gcaaacgaaa caatcaaaaa agctatgaaa caatagtcct tagttattct ataaaaagta
    49081 gttttttaaa gaacctaaga gtgtataccc ccttttccct ctacacagat agtgtaagaa
    49141 aagggggctt ttgtttaaaa tgtaagaaac tgtcacgaaa ttaaaatgaa gttcttacat
    49201 aagcgaatca taaaaaattt cattttgatt ttaaaacagt tcaagaaagt caaaaaatta
    49261 ttctatttga aagagaggtg ccgactgtga aagtcaataa aatccgtatg cgggaaacag
    49321 tgatttccta cgctttccta gcaccagtat tattcttctt tgtcatcttt gtgttggctc
    49381 cgatggtgat gggcttcatt acaagtttct ttaactactc aatgactaaa tttgagtttg
    49441 taggcttgga taactatatc cgtatgttta aagatcctgt ctttacaaaa tctctgatta
    49501 acacagttat tttggttatt ggatctgtac cagttgttgt tctattctca ctctttgtag
    49561 catctcagac ctatcatcaa aatgtcattg ccagatcctt ctaccgtttc gtcttcttcc
    49621 ttcctgttgt aacgggtagt gttgccgtga cagttgtttg gaaatggatt tatgacccac
    49681 tatcagggat tctaaacttt gtccttaagt ccagccacat catcagccaa aacatttctt
    49741 ggttgggaga taaaaactgg gcattgatgg cgattatgat tattctcttg accacttcag
    49801 ttggtcagcc catcatcctt tatatcgctg ccatggggaa tattgacaat tcactggttg
    49861 aagcggcgcg tgttgatggt gcaactgagt ttcaagtttt ttggaagatt aaatggccaa
    49921 gccttcttcc aacaactctt tatattgcaa tcatcacaac aattaactca ttccagtgtt
    49981 tcgccttgat tcagcttttg acatctggtg gtccaaacta ctcaacaagt accttgatgt
    50041 actaccttta cgaaaaagcc ttccaattga cagaatacgg ctatgccaac acaattggtg
    50101 tcttcttggc agtcatgatt gctatcgtaa gctttgttca atttaaagta cttggaaacg
    50161 acgtagaata ctaaagaaag gagacagcta tgcaatctac agaaaaaaaa ccattaacag
    50221 cctttactgt tatttcaaca atcattttgc tcttgttgac tgtgctgttc atctttccat
    50281 tctactggat tttgacaggg gcattcaaat cacaacctga tacaattgtt attcctcctc
    50341 agtggttccc taaaatgcca accatggaaa acttccaaca actcatggtg cagaaccctg
    50401 ccttgcaatg gatgtggaac tcagtattta tctcattggt aaccatgttc ttagtttgtg
    50461 caacctcatc tctagcaggt tatgtattgg ctaaaaaacg tttctatggt caacgcattc
    50521 tatttgctat ctttatcgct gctatggcgc ttccaaaaca agttgtcctt gtaccattgg
    50581 tacgtatcgt caacttcatg ggaatccacg atactctctg ggcagttatc ttgcctttga
    50641 ttggatggcc attcggtgtc ttcctcatga aacaatttag tgaaaatatt cctacagagt
    50701 tgcttgaatc agctaaaatc gacggttgtg gtgagattcg taccttctgg agtgtagcct
    50761 tcccgattgt gaaaccaggg tttgcagccc ttgcaatctt taccttcatc aatacttgga
    50821 atgactactt catgcagttg gtaatgttga cttcacgtaa caatttgacc atctcacttg
    50881 gggttgcgac catgcaggct gaaatggcaa ccaactatgg tttgattatg gcaggagctg
    50941 cccttgctgc tgttccaatc gtcacagtct tccttgtctt ccaaaaatcc ttcacacagg
    51001 gtattactat gggagcggtc aaaggataat actctgcgaa aatcgaatgc aaactacgtc
    51061 agcttcacct tgccatactt aagtattgcc tgcggttagc ttcctagttt gttcttcaat
    51121 tttcattgag tataggaaaa tcaatctatc aagatacaga agtatatttt atagatttag
    51181 agaatataga agttataagt gtctacaaaa tggagggtat gcagttactt tatgaagttt
    51241 tgtcagacac ttatcaactt aagaatgatt ttagttaatt atcagaaacg aaggaaagag
    51301 tatgattttt gacgatttga aaaacatcac cttttacaaa gggattcatc ccaatttaga
    51361 caaagctatc gactacctct accaacatcg taaagattca ttcgaattag gaaagtatga
    51421 gattgatgga gataaggtct ttctagttgt tcaggaaaat gtcctcaatc aagttgagaa
    51481 taatcaattt gaacaccata agaactatgc agatttgcat ttgctgatag aagggcatga
    51541 atattcgagc tacggttcac gtatcaaaga cgaggcagta gcattcgacg aagcgactga
    51601 cattggcttt gttcattgtc atgaacacta cccactcttg ttgggttatc ataattttgc
    51661 gattttcttc ccaggtgagc cacatcagcc aactggctat gcaggtatgg aagaaaaggt
    51721 tcgaaaatat ctctttaaaa ttttgattga ttaaaaatag gatgaattgt ttttttgtaa
    51781 agctttgaca atactctacc atgaaattga tctttatgag gtagagaaat gagaataaaa
    51841 tatttaaaaa ttggtatctt ctaagcatgc tgcaagagct agtttcttag atggacagga
    51901 aattacagtt gatgagatgt cctggataat taatggcatt gtgaatgcat tgattggtag
    51961 atacataaaa ttaggtactt atgcagctaa gtatggtatt ggtatagcac gctcgatctt
    52021 aagtagggca gctgcaactg cagcagcaag agtaggatta ctgaccaaga tttctggatg
    52081 gattttacga gtagctgtga atgtagctga tgtatatggt aatttcgcca acaatattgc
    52141 tgcagcttgg gatgcatatg ataaaattcc taacaatggt cgtataaact tttaaaatac
    52201 gagaatgaaa gcactttgta tttttttatt gaatatgtta gcttggacag tgcttgcaat
    52261 gataattcgt ggagggctag atggatttga taggcatact tggagtacta ttttaattgc
    52321 ttcgctgttc ggggtatatg attataagcc catagataaa aatagaaaaa agtccaaaag
    52381 aaaaaagaaa aaatagattt gttcatggta gggacttatg aaagctttac tgacaaaaaa
    52441 gaaaacagtt tacaaagaaa aatgatggag gagcaaacat ggcacaaaaa ggagtaagcc
    52501 ttatcaaggc agcatttgat acagataact ttctcatgcg ttttagtgag aaggtcttgg
    52561 acatcgtgac agccaatctt ctttttgtcg tctcttgttt acccatcgtg acgattggag
    52621 tggctaaaat cagcctctac gagaccatgt tcgaagttaa gaagagcaga cgggtgcctg
    52681 tttttaaaat ctatctaaga tctttcaagc aaaatctgaa actaggtctt cagctgggtt
    52741 taatggagtt aggaattgtg tttcttaccc tttcagatct ctatcttttc tggggtcaaa
    52801 cagctctgcc cttccaattg ctgaaagcca tttgtttagg tattctgatt tttcttacta
    52861 tcgtgatgct ggctagttac cctatcgcgg cacgttatga cctatcttgg aaagaaattc
    52921 ttcaaaaagg attgatgttg gctagtttta actttccttg gttcttcctc atgttagcca
    52981 ttcttgtcct cattgtgatg gttctttatc tgtccgcctt cagtctactc ttaggtggct
    53041 cagtcttcct actttttggg tttggactat tggtctttat ccagactgga ttgatggaga
    53101 aaattttcgc aaaataccaa taggagcttt atttctgaaa ctactttcaa aggctccaaa
    53161 cgctattcta taagcgagaa actaaaatct aagtgtctat aagatattga aagccttttc
    53221 ggtaaagtgt atactaaaga agtaaagaaa aatctgcttt agcagaaaat aaaaataata
    53281 ggagaaaatc tatgtcagat ttgaaaaaat acgaaggtgt cattccagcc ttctacgcat
    53341 gttatgatga gcaaggagaa gtaagtccag agcgtacgcg tgccttggtt caatacttca
    53401 ttgataaagg tgttcaaggt ctttatgtca atggttcttc tggtgaatgt atctaccaaa
    53461 gcgttgaaga tcgcaagttg attttggaag aagtcatggc ggtagctaaa ggtaaattga
    53521 ccattattgc ccatgttgcc tgcaacaata ctaaagacag tatggaactt gctcgccatg
    53581 ctgaaagctt gggagtagat gctattgcaa cgattccacc aatttatttc cgcttgccag
    53641 aatactcagt tgccaaatac tggaacgata tcagttctgc agctccaaac acagactacg
    53701 tgatttacaa cattcctcaa ttggcagggg ttgctttgac tccaagcctt tacacagaaa
    53761 tgttgaaaaa tcctcgtgtt atcggtgtga agaactcttc tatgccagtt caagatatcc
    53821 aaacctttgt cagccttggt ggggaagacc atatcgtctt taacggtcca gatgaacagt
    53881 tcctaggtgg tcgcctcatg ggtgccaaag ctggtatcgg tggtacttat ggtgctatgc
    53941 cagaactctt cttgaaactc aaccaattga ttgcggataa agatttagaa acagcgcgtg
    54001 agttacagta tgctatcaac gctatcattg gtaaattgac tgctacacat ggaaatatgt
    54061 acggtgtcat caaagaagtt ttgaagatca atgaaggctt gaatattggt tctgttcgtt
    54121 caccattgac accagtgact gaagaagatc gtccagttgt agaagcggct gctgccttga
    54181 ttcgtgaaac caaggagagc ttcctctaat ctaaaaggag gtatttatga catactacgt
    54241 tgcaattgat atcggtggaa ccaacatcaa gtatggtttg gttgatcaag aggggcaact
    54301 tcttgaatcg catgaaatgc caactgaggc gcataagggt ggacctcata tcttacaaaa
    54361 gaccaaagat atcgtagcta gttatttaga aaaaggccca gtagcaggtg ttgccatatc
    54421 ttctgctggg atggtggatc cggataaggg tgagattttc tatgctgggc cgcaaatccc
    54481 taactacgca ggcacccagt tcaaaaagga aatcgaagaa agctttacta ttccttgtga
    54541 gattgaaaat gatgtcaact gtgcaggtct tgctgaggca gtatctggtt caggcaaggg
    54601 agcaagtgtg acactttgct tgaccattgg aaccggtatc ggtggttgct tgattatgga
    54661 taggaaagtc ttccatggtt ttagcaattc agcctgtgaa gtcgggtata tgcatatgca
    54721 ggatggagct tttcaagact tggcttctac aacagcttta gtgaaatatg tagctgaagc
    54781 ccatggagaa gatgttgatc agtggaatgg ccgtagaatt ttcaaagaag ccactgaagg
    54841 aaacaaaatc tgcatggaag gtattgaccg tatggttgac tatctaggaa aaggtctggc
    54901 aaatatttgc tacgttgcca atccagaagt ggttattctt ggtggtggta tcatggggca
    54961 agaggctatc ctcaaaccta agatccgcac agccttgaaa gaggctttgg taccaagttt
    55021 agcagaaaaa acacgattag aatttgccca tcaccaaaat acagcaggga tgttgggtgc
    55081 atattatcat tttaagacaa aacaatccta gtttggctca gccaaactag gattttctta
    55141 cacgtttttg tctacgatag ccgttgagtt ttttattttc ccagtagcta ttaaagattt
    55201 tttccttgct ttcgcgattg atttccaaaa agtaggcata aatcaaatcg ataaagaaga
    55261 gcataggaag ttgagcggat attcgttgga tataggaggg ttggctgtgg gtggctacaa
    55321 gaacagtctc tgtataggtc tggctatctt tattgggaac acttgtaaag agtacagtct
    55381 ttgcccccat ctccttggca tctaatagac tatctaaaat agaaggagtt gagcctgaaa
    55441 gtgagaagcc cagtactaga caattttcat ccatgatgct ggttgtccag gcaaagccgt
    55501 cttggtctgt caaagcttcg cagaccacac ctagtcgcat aaaacgtaat ttcatttcac
    55561 gggcgacgag gccagaactc cctgttccaa agaagtagat acgctcagca tcttcgatta
    55621 gctgggcaat tcgctctagt tggatttcgt caatcaagtc ttgtgtttgt tccctcatat
    55681 tgctataact tctgaggact cgtttggtca gtggactgtg cttggagact cggttggctt
    55741 gattttctgc ctgatgttgg tattggaaaa taaattctcg gtagccagta aagccacact
    55801 ttttagcaaa gcgggtcaaa gcagcttgag aaatatgtaa tttttgggtg acttgttgag
    55861 aagataaatc atctgtaatc gtttcagctt gcaaaaaata gcgagcgatt tcttgctcta
    55921 ggtctgtcat ttcttcaaaa tgtgaatcaa tgatagttgc gatatctggt ttgtccatag
    55981 ggaaagctcc tttacatgag tcatactgga agactagatc agggaatagt cacacttcat
    56041 tataacacat aatataagga tagataaata aaaacgcatc tctgttttaa aaacgaaaaa
    56101 atcgaaaaag cttctctctt ttccataatt ttctactcaa attgtggtac aattaagagt
    56161 aagattttaa gttagaaatg agactgattt gtatgagaaa atttaacagc cattcgattc
    56221 cgattcggct taatttattg ttttcaatcg tcattttact ctttatgacc attattggtc
    56281 gtttgttgta tatgcaggtt ttgaacaagg atttttacga aaaaaagcta gcctcagcta
    56341 gtcagaccaa gattacaagc agttcagccc gtggggaaat ttatgatgct agtggaaaac
    56401 ctttggtaga aaatacgtta aagcaggttg tttcctttac gcgtagcaat aaaatgacgg
    56461 ctacagactt aaaagaaaca gctaaaaagt tactgactta tgtgagcatc agttctccaa
    56521 atttgacaaa acgccagctg gcggattact atttggctga tcctgaaatc tataaaaaaa
    56581 cagtggaagc tctcccaagc gagaaacgct tggattcaga tggcaatcgt ctatccgaat
    56641 cagaactgta taacaatgcg gtcgatagtg tccaaacaag tcaactaaac tatacagagg
    56701 atgaaaagaa agaaatctat ctttttagtc agttaaatgc tgttggaaac tttgcgacag
    56761 gaaccattgc tacagatcct ctaaatgatt ctcaggtggc tgttattgcc tctatttcaa
    56821 aggagatgcc tggcattagt atttctactt cttgggatag aaaggttttg gaaacttccc
    56881 tttcttctat agttgggagt gtatccagtg aaaaagctgg tctcccagcg gaagaagcag
    56941 aagcctatct taaaaaaggc tattctctaa atgaccgtgt aggaacctcc tatttggaaa
    57001 agcaatatga agagacctta caaggaaaac gatcggtaaa agaaatccat ctggataaat
    57061 atggcaatat ggaaagcgtg gatacaattg aggaaggtag taagggaaac aatatcaaac
    57121 tgaccattga tttggccttc caagatagcg tggatgcttt gctgaaaagt tatttcaatt
    57181 ctgagctaga aaatggtgga gccaagtatt ctgaaggtgt ctatgcagtc gcccttaacc
    57241 caaaaacagg tgcggttttg tctatgtcag ggattaaaca tgacttgaaa acgggagagt
    57301 tgacgcctga ttccttggga acggtaacca atgtctttgt tccaggttcg gttgtcaagg
    57361 cggcgaccat cagctcaggt tgggaaaatg gagtcttgtc aggaaaccag accttgacag
    57421 accagtccat tgtcttccaa ggttcagctc ccatcaattc ttggtatact caggcttacg
    57481 gttcattccc tatcacagcg gtccaagctc tggagtattc atcaaatacc tatatggtcc
    57541 aaacagcctt aggtcttatg gggcaaacct atcaacccaa tatgtttgtc ggcaccagca
    57601 atctagagtc tgctatggag aaactgcgtt caacctttgg cgaatatggc ttgggtactg
    57661 cgacaggaat tgacctacca gatgaatcta ctggatttgt tcccaaagag tatagctttg
    57721 ctaattacat tactaatgcc tttgggcagt ttgataacta tacgccgatg cagttggctc
    57781 agtatgtagc aactattgca aataatggtg ttcgtgtggc tcctcgtatt gttgaaggca
    57841 tttatggtaa taatgataag ggaggactgg gtgacttgat tcagcaactg caaccgacag
    57901 agataaataa ggtcaatata tccgactccg atatgagcat cttgcaccaa ggtttttatc
    57961 aggttgccca tggtactagt ggattgacaa ctggacgtgc cttttcaaat ggtgccttgg
    58021 tatccattag cggaaaaaca ggtacagccg aaagctatgt ggcagatggt cagcaagcaa
    58081 ccaataccaa tgcggtggcc tatgccccat ctgataatcc ccaaatcgct gtcgcagtgg
    58141 tctttcctca taataccaat ctaacaaatg gtgtaggacc ttccattgcg cgtgacatta
    58201 tcaatctgta tcaaaaatac catccaatga actagaaagg aaattatgct ttatccaaca
    58261 cctattgcca agttgattga cagttattct aagttaccag gtatcgggat taagacggct
    58321 acgcgtctgg ccttttatac gattgggatg tctgctgatg atgtcaatga atttgcaaaa
    58381 aatctccttt ctgctaagag agaattgaca tattgttcta tttgtggacg tttgacagac
    58441 gacgatcctt gttctatctg tactgatccg actcgtgacc agacaacaat tttagttctt
    58501 gaggatagta gagatgtggc agccatggaa aatatccaag aataccatgg actctatcat
    58561 gtcctgcatg gcctcatttc tcctatgaat ggtatcagtc cggacgatat caatctcaag
    58621 agccttatga ctcgtcttat ggatagtgag gtttcagaag tgattgtggc gactaatgct
    58681 acagcggatg gtgaagcgac ttccatgtat ctttcacgtt tgctcaagcc agctggtatc
    58741 aaggttacgc gtctagcacg aggtctcgct gtgggagcgg acattgagta tgcggacgaa
    58801 gtgacactct tacgagcgat tgaaaatcgg acagagttgt aagtgtaggc aaatttacga
    58861 actcccttca tttataaaaa atcaaagagg ctgaaaatcg ttcctatcgg cctctttttg
    58921 tatagtgtga tgagtaggat cgggttcaag ttttaaaaaa ccaagcaaat atgatatact
    58981 aaagagcgag tattctagta gaattaggac aaataatatg aaacaaacga ttattctttt
    59041 atatggtgga cggagtgcgg aacgcgaagt ctctgtcctt tcagctgaga gtgtcatgcg
    59101 tgcggtcaat tacgaccgtt tcacagtcaa gactttcttt atcagtcagt caggtgactt
    59161 tatcaaaaca caggaattta gtcatgctcc ggggcaagaa gaccgtctca tgaccaatga
    59221 aaccattgat tgggataaga aagttgcacc aagtgctatc tacgaagaag gtgcagtggt
    59281 ctttccagtc cttcacgggc caatgggaga agatggctct gttcaaggat tcttggaagt
    59341 tttgaaaatg ccttacgttg gttgcaacat tttgtcatca agtcttgcca tggataaaat
    59401 cacgactaag cgtgttctgg aatctgctgg tattgcccaa gttccttatg tggctatcgt
    59461 tgaaggcgat gatgtgactg ctaaaatcgc tgaagtggaa gaaaaattgg cttatccagt
    59521 cttcactaag ccgtcaaaca tggggtctag tgtcggtatt tctaagtctg aaaaccaaga
    59581 agaactccgt caagccttaa aacttgcctt ccgatatgac agccgtgtct tggttgagca
    59641 aggagtgaat gcccgtgaaa ttgaggttgg cctcttgggt aactacgatg tcaagagcac
    59701 gctacctgga gaagttgtca aggacgttgc cttttatgac tacgatgcca agtatattga
    59761 taacaagatt actatggata ttcctgccaa aatcagtgat gatgtggtag ctgtcatgcg
    59821 tcaaaatgca gaaacagcct tccgtgccat tggtggcctt ggtctatctc gttgcgattt
    59881 cttctataca gataagggag agatttttct caacgagctc aataccatgc caggtttcac
    59941 ccagtggtct atgtacccac tactttggga caatatgggg atcagctacc cagaactaat
    60001 cgagcgtttg gttgaccttg ccaaggaaag ttttgacaag cgcgaagcgc atttgatata
    60061 aaatgaaaga gagggtagaa gccagaacca tcactgcaag gtgactagag ttctcggact
    60121 tcagcccttt ttaaaggagt agaaatgaaa ttaacaatcc atgaagttgc ccaagttgtt
    60181 ggagccaaaa atgatatcag tatctttgag gacacccagt tagaaaaagc tgagtttgat
    60241 agtcgtttga ttggaactgg agatttattt gtgcccctaa aaggtgtgcg tgacggtcat
    60301 gactttatcg aaagagcttt tgaaaatggt gcggcagcaa ccctgtctga gaaagaggtt
    60361 gcaaatcatc cctacattct agtagatgat gttttgactg cctttcaaca actagctgcc
    60421 tactatcttg aaaaaacagc tgttgatgtc tttgcggtta cgggttcaaa tggcaagaca
    60481 acgactaagg atatgttggc gcatttactg tcaacaagat acaagaccta caaaacacaa
    60541 ggcaattaca ataatgagat tggccttcct tacacagttc tccacatgcc tgaaggaaca
    60601 gaaaagttgg tcttggagat ggggcaggac cacttgggag atattcatct cttgtctgaa
    60661 ttggctcgtc caaaaacagc catcgtgacc ttggttggag aagctcattt ggcctttttc
    60721 aaagatcgtt ctgagattgc taaaggaaaa atgcaaattg cagacggaat ggcttcaggt
    60781 tccttgcttt tagcgccggc tgaccctatc gtagaggact atttgccaac tgataaaaag
    60841 gtggttcgtt ttggtcaagg agcagagctg gaaattactg acttggttga gcgcaaagat
    60901 agtctgacct tcaaggccaa tttcttagag caagtccttg atttgccagt aactggcaag
    60961 tacaatgcga caaatgctat gattgcatcc tatgttgcct tgcaagaagg agtttcagag
    61021 gagcaaattc gtttggcctt ccaacatctt gaattgacgc gtaaccgtac cgagtggaag
    61081 aaagcagcca atggagcaga catcttgtca gatgtttaca atgccaatcc aactgctatg
    61141 aagctgattt tagagacctt ctctgccatt ccagccaatg aaggtggcaa gaaaattgca
    61201 gtgttggcgg atatgaagga acttggtgtc cagtctgttc aacttcataa tcagatgatt
    61261 ttgagccttt cgccagatgt gcttgatact gttattttct acggagaaga tattgctgaa
    61321 ttagcccaac ttgctagtca aatgttccca atcggacacg tttattactt caagaaaaca
    61381 gaagaccaag accaatttga agacctagtt aagcaggtca aagaaagcct tggggctcat
    61441 gaccaaatcc tgctcaaagg ctctaactct atgaatctag ccaagttggt agaaagttta
    61501 gaaaatgaag acaagtgatt ttgtcaagta tttgcaaaga atgattgcca ttacagatac
    61561 tggattaacc tttacaaaag atccgtttga ccgtgagcgc tacgaagact tgcgagacct
    61621 tctatctgaa atgttgaatc aagcatcaga ccttgattcc gaagaagtgg cagaagtctt
    61681 gaagccaact tctgcttatg cgactccctt aatggacgtc cgtgcttgga ttgttgagga
    61741 cgaaaagatt tgtctggtta ggggacaagg agaggatagt tgggctttgc caggtggctt
    61801 tggtgaagtc ggctattctc caactgaaaa tattctcaag gaaattgaag aagaaaccgg
    61861 ttttaaagcc aaagttgaaa gactgctagc tgtttttgat accaatcgtt tccaactaca
    61921 gagcaaacaa tatgcaaagt ttgtttttga atgtaagctt ctcgatggac aattccaaga
    61981 aaatcaagaa atcgctgacc ttcaattttt tgcaattgac ccactgccga atttatctga
    62041 aaaacgcatt accaaggagc aaatcgagat tctttggcag gtttatcaag gtcagaggga
    62101 gcaatatctt gactaagaag atgattatcg tatttctaaa ttcatttttc ttaagtagca
    62161 tggtataata aaatgcagga aaattttgaa tcatgaggaa gactagatga atttatggga
    62221 tattttcttt acgactcagg caaccgagcc gcccaaattt gacctttttt ggtatgttag
    62281 cctatttacg ctcttagcct taacctttta tacagcccat cgctatcgtg aaaagaaggt
    62341 ttaccaacga tttttccaaa tcttgcagac tgttcagtta atccttcttt atggttggta
    62401 ctgggtcaat catatgccac tgtcagaaag cctacccttt taccattgcc gtatggctat
    62461 gtttgtggta ctcttgcttc ctggtcagtc caaatataaa caatactttg cattattggg
    62521 aacatttggg acattagcag cctttgttta tccagtgcca gatgcttacc cttttccaca
    62581 tatcaccatt ctatccttta tctttggtca tttagcactc ttggggaact ctctagttta
    62641 tctattgaga cagtataatg cgcgattgct ggatgtgaag ggaatttttc tcatgacctt
    62701 tgccctaaat gccttgattt ttgtggtcaa tttggtgaca ggtggcgatt acggattttt
    62761 gacaaaaccg ccattggttg gggatcacgg tctagtagct aattatttac ttgtttcaat
    62821 tgtgctggta gctactatca gtttgactaa gaaaatctta gaattctttt tagctcaaga
    62881 agcagaaaaa atgattgcaa aggaagctta acacagagct ttcttttttg ctcttagaga
    62941 gtttttacaa gcagcttata aaataagaat ttctgaatag acaaactcaa aaaatggctg
    63001 ggaaatttag gaaaaaagca agcacgatta aattttttgt gttataatat tttgtgaata
    63061 gctatgccta tgtttagcta tggaataata cgaagtgcga aacttggaag atagagagga
    63121 agcgatgtaa tggctagaga aggctttttt acaggtctag atattggaac aagctctgtc
    63181 aaggtgcttg tggccgagca gagaaatggt gaattaaatg taattggcgt gagtaatgcc
    63241 aaaagtaaag gtgtaaagga tggaattatt gttgatattg atgcagcagc aactgctatc
    63301 aagtcagcca tttcccaagc ggaagaaaag gcaggcattt cgattaaatc agtaaatgtc
    63361 ggcttgcctg gtaatctttt gcaggtagaa ccaactcagg ggatgattcc agtaacatct
    63421 gatactaagg aaattacgga tcaagatgtt gaaaatgttg tcaaatcagc tttgacaaag
    63481 agtatgacac ctgaccgtga agtcattacc tttattcctg aagaatttat tgtggatggt
    63541 ttccaaggga ttcgtgaccc acgtggcatg atgggggttc gccttgaaat gcgtggtttg
    63601 ctttatacag gacctcgtac tatcttgcac aatttgcgta agacggttga gcgtgcaggt
    63661 gttcaggttg aaaatattat catttcacca ctagcaatgg ttcagtctgt tttgaatgaa
    63721 ggggaacgtg aatttggtgc tacagtgatt gatatggggg caggtcaaac gactgtcgct
    63781 acaatccgta atcaagaact ccagttcaca catattctcc aagaaggtgg agattatgta
    63841 actaaagata tctccaaggt tttgaaaacc tctcgcaaat tagcggaagg cttgaaactg
    63901 aattacgggg aagcctatcc gcctcttgca agcaaagaaa ccttccaagt agaggttatt
    63961 ggagaagtgg aagcagtcga agtgacggaa gcctacttgt cagaaattat ttctgcacga
    64021 atcaagcaca tccttgaaca aatcaagcaa gaattagata gaaggcgtct attggacctc
    64081 cctggtggta ttgtcttaat cggtgggaat gccattttac caggtatggt tgagcttgct
    64141 caggaagtct ttggcgtccg tgtcaagctt tatgttccaa atcaagttgg tatccgtaat
    64201 ccagcctttg cgcatgtgat tagtttatca gaatttgcgg gtcaattaac agaagttaat
    64261 cttttggctc agggagcgat aaaaggtgag aatgacttaa gtcatcagcc aattagtttt
    64321 ggtgggatgc tgcaaaaaac agctcagttt gtacaatcaa cgcctgttca accagctcct
    64381 gctccagaag tagagtcggt ggcgcctaca gaaccaatgg cggatttcca acaagcttca
    64441 caaaataaac cgaaattagc agatcgtttc cgtggcttga tcggaagcat gtttgacgaa
    64501 taaagaggaa aaataaatta tgacattttc atttgataca gctgctgctc aaggggcagt
    64561 gattaaagta attggtgtcg gtggaggtgg tggcaatgcc atcaaccgta tggtcgacga
    64621 aggtgttaca ggcgtagaat ttatcgcagc aaacacagat gtacaagcat tgagtagtac
    64681 aaaagctgag actgttattc agttgggacc taaattgact cgtggtttgg gtgcaggagg
    64741 tcaacctgag gttggtcgta aagccgctga agaaagcgaa gaaacactga cggaagctat
    64801 tagtggtgcc gatatggtct tcatcactgc tggtatggga ggaggctctg gaactggagc
    64861 tgctcctgtt attgctcgta tcgccaaaga tttaggtgcg cttacagttg gtgttgtaac
    64921 acgtcccttt ggttttgaag gaagtaagcg tggacaattt gctgtagaag gaatcaatca
    64981 acttcgtgag catgtagaca ctctattgat tatctcaaac aacaatttgc ttgaaattgt
    65041 tgataagaaa acaccgcttt tggaggctct tagcgaagcg gataacgttc ttcgtcaagg
    65101 tgttcaaggg attaccgatt tgattaccaa tccaggattg attaaccttg actttgccga
    65161 tgtgaaaacg gtaatggcaa acaaagggaa tgctcttatg ggtattggta tcggtagtgg
    65221 agaagaacgt gtggtagaag cggcacgtaa ggcaatctat tcaccacttc ttgaaacaac
    65281 tattgacggt gctgaggatg ttatcgtcaa cgttactggt ggtcttgact taaccttgat
    65341 tgaggcagaa gaggcttcac aaattgtgaa ccaggcagca ggtcaaggag tgaacatctg
    65401 gctcggtact tcaattgatg aaagtatgcg tgatgaaatt cgtgtaacag ttgttgcaac
    65461 gggtgttcgt caagaccgcg tagaaaaggt tgtggctcca caagctagat ctgctactaa
    65521 ctaccgtgag acagtgaaac cagctcattc acatggcttt gatcgtcatt ttgatatggc
    65581 agaaacagtt gaattgccaa aacaaaatcc acgtcgtttg gaaccaactc aggcatctgc
    65641 ttttggtgat tgggatcttc gccgtgaatc gattgttcgt acaacagatt cagtcgtttc
    65701 tccagtcgag cgctttgaag ccccaatttc acaagatgaa gatgaattgg atacacctcc
    65761 atttttcaaa aatcgttaag taaatgaatg taaaagaaaa tacagaactt gtttttcgag
    65821 aagttgcaga ggctagtctg agtgctcatc gagagagtgg ttcggtctct gtcattgcag
    65881 ttaccaagta tgtagatgta ccgacagcgg aagccttgct tccgctaggt gttcatcata
    65941 tcggtgaaaa tcgtgtagat aagtttctgg aaaaatatga agctttaaaa gatcgagatg
    66001 tgacttggca tttgattggt accttgcaaa gacgtaaggt gaaagatgtc attcaatacg
    66061 ttgattattt ccatgcattg gactcagtaa agctagcagg ggaaattcaa aaaagaagtg
    66121 accgagtcat caagtgtttc cttcaagtaa atatttctaa agaagaaagc aaacacggtt
    66181 tttcgagaga ggaactgctg gaaatcttgc cagagttagc cagactagat aagattgaat
    66241 atgttggttt aatgacgatg gcaccttttg aggctagcag tgagcagttg aaagagattt
    66301 tcaaggcgac ccaagattta caaagagaaa ttcaagagaa acaaattcca aatatgccta
    66361 tgaccgagtt aagtatggga atgagtcgtg attataaaga agcgattcaa ttcggttcca
    66421 cttttgttcg tataggtaca tcatttttta agtaggagag aaccatgtct ttaaaagata
    66481 gattcgatag atttatagat tattttacgg aggatgagga ttcaagtctc ccttatgaaa
    66541 aaagagatga gcctgtgttt actccagtaa attcttcaca ggaaccggct ctcccaatga
    66601 atcaaccttc acagtcggct ggtacaaaag agaacaatat caccagactt catgcaagac
    66661 aacaggaatt ggcaaatcag agtcagcgtg caacggataa ggtcattata gatgttcgtt
    66721 atcctagaaa atatgaggat gcaacagaaa ttgttgattt attggcagga aacgaaagta
    66781 tcttgattga ttttcagtat atgacagagg tgcaggctcg tcgttgtttg gactatttgg
    66841 atggagcttg tcatgtttta gctggaaatt tgaaaaaggt agcttctacc atgtatttgt
    66901 tgacaccagt gaatgttatt gtaaatgttg aagatatccg tttaccagat gaagatcaac
    66961 agggtgagtt cggttttgat atgaagcgaa atagagtacg ataatgattt ttttaattcg
    67021 tatgatttat aatgcagtgg atatttactc cctgattttg gtagccttcg ctgtcatgtc
    67081 ttggtttcca ggtgcctacg aatccagttt aggtcgttgg attgtagcgt tggtgaaacc
    67141 agtgcttgct cccttgcaac gcctgccttt acagatagcg ggtcttgatt tatctgtttg
    67201 ggtcgcgatt gttttggttc gatttttagg agaaaaccta gtgcgttttc tggcgatgat
    67261 aggatgaata aagggattta tcagcatttc tccatagaag atcgtccatt tcttgacaag
    67321 ggaatggaat ggataaagaa ggtagaagat agctatgctc cttttttaac tccttttatc
    67381 aatcctcatc aggagaagct attaaagatt ttggccaaaa cctatggtct tgcttgtagc
    67441 agtagtgggg aattcgtctc gagtgagtat gttcgagttt tattataccc agattatttc
    67501 caaccagagt tttcagattt tgaaatatct ctccaggaaa ttgtgtattc caataaattt
    67561 gaacatttaa cgcatgctaa gattttaggg acagtcatca atcaattagg gattgaacgg
    67621 aaactttttg gagatatcct agtagatgaa gaacgggcgc agattatgat taatcagcag
    67681 tttcttcttc tctttcaaga tggactaaag aaaattggtc gtatacctgt ttcgctggag
    67741 gaacgtcctt tcaccgagaa aatagataag ctagaacagt atcgagaact ggatttatct
    67801 gtgtctagtt ttcgattaga tgttctttgt tcaagttgga gacttgatta gtgtgagaaa
    67861 atttggtcgc ttgagattac ttcaagataa gggacaaacg aaaaaagaga agaaaaaaat
    67921 aaccgtccag ttattattaa gtaagtgagg aatagaatgc caattacatc attagaaata
    67981 aaggacaaga cttttggaac tcgattcaga ggttttgatc cagaagaagt cgatgaattt
    68041 ttagatattg tggttcgtga ttacgaagat cttgtgcgtg cgaatcatga taaaaatttg
    68101 cgtattaaga gtttagaaga gcgtttgtct tactttgatg aaataaaaga ttcattgagc
    68161 cagtctgtat tgattgctca ggatacagct gagagagtga aacaggcggc gcatgaacgt
    68221 tcaaacaata tcattcatca agcagagcaa gatgcgcaac gcttgttgga agaagctaaa
    68281 tataaggcaa acgagattct tcgtcaagca actgataatg ctaagaaagt cgctgttgaa
    68341 acagaagaat tgaagaacaa gagccgtgtc ttccaccaac gtctcaaatc tacaattgag
    68401 agtcagttgg ctattgttga atcttcagat tgggaagata ttctccgtcc aacagctact
    68461 tatcttcaaa ccagtgatga agcctttaaa gaagtggtta gcgaagtact tggagaaccg
    68521 attccagctc caattgaaga agaaccaatt gatatgacac gtcagttctc tcaagcagaa
    68581 atggaagaat tacaagctcg tattgaggta gccgataaag aattgtctga atttgaagct
    68641 cagattaaac aggaagtgga aactccaact cctgtagtga gtcctcaagt tgaagaagag
    68701 cctctgctca tccagttggc ccaatgtatg aagaaccaga agtagctcca gtgcatccga
    68761 caggtccaac accagctaca gaaactgttg attcagcacc gggatttgaa gcaccgcaag
    68821 aatctgttac aattttataa gaaatattct gagaacaata tcttatcctt atattcccag
    68881 cgagcaggag atggtgtgag tcctgcattc cctatcgata agattatcct ctcaaactat
    68941 caagtctgaa tctagtaaga tttgacgttc cccacgttac gggataagag ggagaaagac
    69001 taaaactttt tccgaataaa ggtggtacca cgattttcgt cctttttgga agtcgtggtt
    69061 tttaatttgt tattatttat aaaggagata ccatgaaact caaagacacc cttaatcttg
    69121 ggaaaactga attcccaatg cgtgcaggcc ttcctaccaa agagccagtt tggcaaaagg
    69181 aatgggaaga tgcaaaactt tatcaacgtc gtcaagaatt gaaccaagga aaacctcatt
    69241 tcaccttgca tgatggccct ccatacgcta acggaaatat ccacgttgga catgctatga
    69301 acaagatttc aaaagatatc attgttcgtt ctaagtctat gtcaggattt tacgcaccat
    69361 ttattcctgg ttgggatact catggtctgc caatcgagca agtcttgtca aaacaaggtg
    69421 tcaaacgtaa agaaatggac ttggttgagt acttgaaact ttgccgtgag tacgctcttt
    69481 ctcaagtaga taaacaacgt gaagatttta aacgtttggg tgtttctggt gactgggaaa
    69541 atccatatgt gaccttgact cctgactatg aagcagctca aattcgtgta tttggtgaga
    69601 tggctaataa gggttatatc taccgtggtg ctaagccagt ttactggtca tggtcatctg
    69661 agtcagccct tgctgaagca gagattgaat accatgactt ggtttcaact tccctttact
    69721 atgccaacaa ggtaaaagat ggcaaaggag ttctagatac agatacttat atcgttgtct
    69781 ggacaacgac tccatttact atcacagcct ctcgtggttt gacggttggt gcagatattg
    69841 attacgtttt ggttcaacct gctggtgaag ctcgtaagtt tgtcgttgct gctgaattat
    69901 tgactagctt gtctgagaaa tttggctggg ctgatgttca agttttggaa acttaccgtg
    69961 gccaagaact caaccacatc gtaacagaac acccatggga tacagctgta gaagagttgg
    70021 taattcttgg tgaccacgtt acgactgact ctggtacagg tattgtccat acagcccctg
    70081 gttttggtga ggacgattac aatgttggta ttgctaataa tcttgaagtc gcagtgactg
    70141 ttgatgaacg tggtatcatg atgaagaatg ctggtcctga atttgaaggt caattctatg
    70201 aaaaggtagt tccaactgtt attgaaaaac ttggtaacct ccttcttgcc caagaagaaa
    70261 tctctcactc atatccattt gactggcgta ctaagaaacc aatcatctgg cgtgcagttc
    70321 cacaatggtt tgcctcagtt tctaaattcc gtcaagaaat cttggacgaa attgaaaaag
    70381 tgaaattcca ctcagaatgg ggtaaagtcc gtctttacaa tatgatccgt gaccgtggtg
    70441 actgggttat ctctcgtcaa cgtgcttggg gtgttccact tcctatcttc tacgctgaag
    70501 atggtacagc tatcatggta gctgaaacta ttgaacacgt agctcaactt tttgaagaac
    70561 atggttcaag catttggtgg gaacgtgatg ccaaagacct cttgccagaa ggatttactc
    70621 atccaggttc accaaacggc gagttcaaaa aagaaactga tatcatggac gtttggtttg
    70681 actcaggttc atcatggaat ggagtggtgg taaaccgtcc tgaattgact tacccagccg
    70741 acctttacct agaaggttct gaccaatacc gtggttggtt taactcatca cttatcacat
    70801 ctgttgccaa ccatggcgta gcaccttaca aacaaatctt gtcacaaggt tttgcccttg
    70861 atggtaaagg tgagaagatg tctaaatctc ttggaaatac cattgctcca agcgatgttg
    70921 aaaaacaatt cggtgctgaa atcttgcgtc tctgggtaac aagtgttgac tcaagcaatg
    70981 acgtgcgtat ctctatggat atcttgagcc aagtttctga aacttaccgt aagattcgta
    71041 acactcttcg tttcttgatt gccaatacat ctgactttaa cccagctcaa gatacagtcg
    71101 cttacgatga gcttcgttca gttgataagt acatgacgat tcgctttaac cagcttgtca
    71161 agaccattcg tgatgcttac gcaaactttg aattcttgac aatctacaag gccttggtga
    71221 actttatcaa cgttgacttg tcagccttct accttgattt tgccaaagat gttgtttaca
    71281 ttgaaggtgc caaatcactg gaacgccgtc aaatgcagac tgtcttctat gacattcttg
    71341 tcaaaatcac caaactcttg actccaatcc ttcctcacac tgcggaagaa atctggtcat
    71401 atcttgagtt tgaagccgaa gacttcgtcc aattgtcaga attaccagaa gttcaaactt
    71461 ttgctaacca agaagaaatc ttggatacat gggcagcctt catggacttc cgtggacaag
    71521 cacaaaaagc cttggaagaa gctcgtaatg caaaagttat cggtaaatca cttgaagcac
    71581 acttgacagt ttatccaaat gaagttgtga aaactctact cgaagcagta aacagcaatg
    71641 tagctcaact tttgatcgtg tctgagttga ccatcgcaga agaaccagct ccggaagctg
    71701 cccttagctt cgaagatgta gtcttcacag ttgaacgcgc tgcaggtgaa gtatgtgacc
    71761 gttgccgtcg tattgaccca acaacagcag aacgtagcta ccacgcagtc atctgtgacc
    71821 actgtgcaag tatcgtagaa gaaaactttg cagatgcagt cgcagaagga tttgaagaga
    71881 aataagattg aaaagtctag gtaaaactca atttgagaag aaaagacaac taattttata
    71941 gtctattaaa cgcattgtat cacgtttttg aacacctgat atgatgcgtt ttttatttat
    72001 tttaaaaatt tgcgaggtat gactttttat actcaacaag aatcaaagag aaacttagca
    72061 agctaacagt agtaatataa aataggaatt tgatattagg gataagattg gtaaatagtg
    72121 taatattttt acaacaataa atttatatag ttatttctgg tttctgaaaa gtattatatt
    72181 atattttatt tcatattata caaattttta ttttataata tcagaaaata ctttttttaa
    72241 aaagcaaata tgatacaatt ttatttgaaa aaaaataaaa aaggagattt tattatgaaa
    72301 tcaagtggta tcgtcggtct tgtgggagga attttacttc ttatttgtcc ttttgtcttg
    72361 ttgggaacag cggtaaatac agctgctaca actcttaatg gaggagctac tgcaggggct
    72421 ttttcaggtg ttgccttact cttgaatgcc ttgaagattg caaatcttgt tcttggtatc
    72481 attgctattg tttactataa aggagataag catgtaggtg cagctccgtc tgtactaatg
    72541 attgtttctg gtgaagttag tctcattcca ttcttaggat gggttggggg gattcttgct
    72601 attatcggag gatctctatt ccttgcaaca ttgaagaaat tcaaatcaga agaataaaag
    72661 gtattttagc atgaaaagaa caaaaaagtt tatcggtata ggagtagctc tattatctct
    72721 ttctcttcta gttgcatgtg gaacataaag ttcaaagaat acttcaacaa gtaatgatga
    72781 gaagacagta gcaacatcca atagttcaaa agaaacaatc actttcgata caccggttgt
    72841 aacagacgat gcgattgaat caatacgcac ttatgcagat tatatagatc tttataaaaa
    72901 tatttttgat gattatttta ctaaagctga ggaaggtttc aaaggcacaa ctatggaaaa
    72961 taatgactcg tttactaaac taaaagagtc aactcaaaaa ttattcgatg cgcagaaaaa
    73021 aaggttaaat aatgaagata gaatagaaac aaccaaaaac aatgtgattg ccaaacattg
    73081 tcaaacagtc ctttcctttt tggttttgac tagctttttt gtgaaaaatt gtgtaaaata
    73141 gaatagataa acgaggggaa acctcggaaa atttaaagga gaatccatct aatggtaaaa
    73201 ttggtttttg ctcgccacgg tgagtctgaa tggaacaaag ctaacctttt cactggttgg
    73261 gctgatgttg atttgtctga aaaaggtaca caacaagcga ttgacgctgg taaattgatc
    73321 aaagaagctg gtatcgaatt tgaccaagct tacacttcag tattgaaacg tgctatcaaa
    73381 acaactaact tggctcttga agcttctgac caattgtggg ttccagttga aaaatcatgg
    73441 cgcttgaacg aacgtcacta cggtggtttg actggtaaaa acaaagctga agctgctgaa
    73501 caatttggtg atgagcaagt tcacatctgg cgtcgttcat acgatgtatt gcctccaaat
    73561 atggaccgtg atgatgagca ctcagctcac acagaccgtc gttatgcttc acttgacgac
    73621 tcagtcattc cagatgctga aaacttgaaa gtgactttgg aacgtgctct tccattctgg
    73681 gaagataaaa tcgctccagc tcttaaagat ggtaaaaacg tattcgtagg agctcacggt
    73741 aactcaatcc gtgcccttgt aaaacacatc aaaggtttgt cagatgatga gatcatggac
    73801 gtggaaatcc ctaacttccc accattggta ttcgaattcg acgaaaaatt gaacgttgtt
    73861 tctgaatact accttggaaa ataaaaaatt gtaagcctag gattgatttc taggcttttt
    73921 atgttagtat ggaagtatga taaggaataa aaaacaagat tatgtactgg cctacaagca
    73981 accagcttca accacttaca tgggttggga agaagaagct ttaccgatag gcaatggttc
    74041 tttaggagca aaagtatttg gccttatagg ggctgaacgg attcaattta atgaaaaaag
    74101 tctctggtct ggaggtccac ttcctgatag ttcagattat cagggtggaa atcttcagga
    74161 tcagtatgtt tttttagctg agattcggca ggctttggag aagagagatt acaatctggc
    74221 taaggaactg gctgagcagc acctaattgg gccaaaaacg agtcaatatg ggacctatct
    74281 gtcttttggg gatattcaca ttgagttcag ccagcaaggt acgactttgt ctcaggtgac
    74341 ggactatcag agacagctga atattagtaa ggcacttgcg acgacttctt atgtctataa
    74401 gggaacgcga tttgaacgta aagcttttgc gagttttcca gatgatctct tgattcaatg
    74461 ttttactaag gaagggttgg aaactctaga ttttactata gaactatcct tgacctgtga
    74521 tttggcttct gatggaaagt atgagcagga aaaatctgat tacaaggagt gtaagttgga
    74581 tattactgat tctcatatct tgatgaaggg aagagttaag gataatgatc tgcggtttgc
    74641 tagttatcta gcttgggaaa cggatggaga tattagagtt tggtcagata gggttcagat
    74701 atcaggagcc agttatgcca atctcttctt ggccgctaag acggattttg cccaaaatcc
    74761 tgctagcaat tatcgcaaga aactagattt agagcaacag gtgatagact tggtggacac
    74821 agctaaagaa aagggctata cccaattgaa atcaaggcat atcgaggact accaagcctt
    74881 attccagcgt gttcaattgg atttggaagc tgatgttgac gcatccacta cagatgattt
    74941 gttaaaaaat tataagccac aagaagggca ggctttggag gagctgttct tccagtatgg
    75001 acggtattta ttgattagtt cgtccagaga ctgcccagat gctctaccag ctaacctaca
    75061 gggagtctgg aatgcggtcg acaatcctcc ttggaattcg gactatcact taaatgtcaa
    75121 tctgcagatg aattattggc cagcctatgt taccaatctc ctagagacgg tctttccagt
    75181 catcaactat gtagatgatt tgcgtgtcta tggtcgtcta gcggctgtaa agtatgcagg
    75241 aatcgtctct caaaaaggtg aggaaaatgg ttggttggtt catactcaag cgactccctt
    75301 tggttggacg gcacctggtt gggattacta ttggggttgg tcaccagctg ccaatgcgtg
    75361 gatgatgcaa accgtttatg aagcctattc attttatagg gaccaagact atctcaggga
    75421 gaaaatttat cccatgttga gggaaacggt tcgtttttgg aatgcctttt tacataagga
    75481 tcagcaggcg cagcgttggg tctcttctcc gtcttattcc ccagaacatg ggccgatttc
    75541 gattggcaat acctatgacc aatctctgat ttggcagtta tttcatgatt ttattcaggc
    75601 tgctcaggaa ttgggactgg atgaggactt gttgactgag gttaaggaga agtctgattt
    75661 actaaatcct ttgcaaatca ctcaatctgg tcgaatcagg gagtggtatg aggaggaaga
    75721 gcagtatttt caaaatgaga aagtggaggc ccagcatcgg cacgcttccc atctagtggg
    75781 actctattct ggcaatctct ttagctacaa gggacaagag tatattgaag cggcgcgtgc
    75841 tatcctcaat gatcgtggag atggcggcac aggctggtcc aaggctaata agatcaatct
    75901 ctgggcgcgt ttgggagatg gcaatcgagc ccataaatta ttggcagagc agttaaagac
    75961 atccaccttg ccaaatcttt ggtgtagcca tcctcctttt cagatagatg gtaattttgg
    76021 tgctactagt ggcatggcag aaatgttact ccagtctcat gcagcttatc tggtacctct
    76081 agctgcccta cctgatgctt ggtcaacagg ttctgtttca ggcttaatgg cacgtggaca
    76141 ttttgaagtg agcatgagct gggaagataa aaaactctta cagttgacca ttttatcaag
    76201 gagtggagga gatttgcgag tttcttatcc agatattgag aagagtgtga ttaaaatgaa
    76261 tcaagaaaaa ataaaagcga aatgcatggg gaaagattgt atttcggtgg caacagcaga
    76321 aggtgatctt gttcaatttt atttttaaga agatgttata aggcagtaat ttgaaacttc
    76381 cttttaataa ggatttgaga atataggcag tttccaacta gttgaaaaag cgttataatg
    76441 ataataggaa gtaatactca atgaaaatca aagagcacaa actaggaagc tagccgcagg
    76501 ttgctcaaaa cagtgttttg aggttgtaga tggaagctga cgtggtttga agagagattt
    76561 tcgaggagta taatttgttt gatagagggt gggtctgatg gcttatattg agatgaaaca
    76621 ctgttacaag cgttatcagg ttggggacac ggagattgtg gccaatcgtg atgtgaattt
    76681 tgagattgaa aagggggagc tggttattat ccttggtgct tcaggtgcag gcaagtcaac
    76741 agttcttaac cttcttgggg gaatggatac caatgatgaa ggggaaatct ggattgatgg
    76801 tgttaatatt gcggattata gttcccacca gcgtaccaat taccgtagaa atgatgtggg
    76861 gtttgttttt cagttttata atctagtttc taatctgaca gctaaggaaa atgtggaact
    76921 ggcttctgaa attgtgacag atgccttgaa tcctgatcag gtcttgacag atgtaggtct
    76981 ggctcatcgt ctcaataact ttccagccca gctttctgga ggggagcaac agcgagtctc
    77041 cattgcacgc gcggtagcca aaaatcctaa aattctcctt tgtgatgaac cgactggagc
    77101 cttggattat cagacgggca agcaggtttt gaaaattctc caagacatgt ctcgtcaaaa
    77161 gggagcgacg gtgatcatcg tgactcataa tggagctttg gcgcccattg ctgatcgcgt
    77221 gattcaaatg cacgatgcca gtgtcaagga tgtggtgctc aaccagcatc ctcaggatat
    77281 tgacagtttg gagtactagc atgatcaagc gaaaaactta ttggaaggac ttaattcagt
    77341 ccttcacagg ctccaagggg cgttttttat ccatcttgat cctgatgatg ttgggatctc
    77401 tagccttagt aggcctcaaa gtaaccagtc ccaacatgga ggcgacagct aatgcttatt
    77461 taacaactgc tcaaaccttg gatttggcag tcatgtctaa ctatggcttg gatcaagcag
    77521 accaagaaga actaaaacag acggagggcg cagaggtcga gtttggctat ttgacagatg
    77581 tgactatgga taatgggcag gatgccattc ggctgtactc caaaccagag cgaatttcaa
    77641 cctttcagct aagaaaggga cgacttcctc agtcagacaa ggaaatcgct ttggccactc
    77701 atttgcaagg ccaatacagc gtgggacagg agattagttt taaagaaaaa gaagagggtc
    77761 attcctcttt aaaagaccat acttatacca ttactggttt tgtggattcg gctgaaatcc
    77821 tctcccagcg agatatgggc tacgcaggaa gtggaagtgg gactctgaca gcctatgggg
    77881 tgattttacc tagtcagttt gatcagaaag tctacaatat agctcgtttg aaatatcaag
    77941 atttagcagg tttaaatgcc ttttcatcag cttatgaaga aaaatccaag caacatcagg
    78001 aagaccttga acaaacttta tcagataatg gcaaggtacg tctgcaactt ttgaaaaaag
    78061 aaggacaaga gtctctagac aaggggcaag agacccttga caaggctcag actaatttgc
    78121 aggaaggcaa gcgtcgttta gcagctgctc aagctcgtat acaggctcaa gaaagtcaac
    78181 tagccttgtt tcctcaagtt cagagagagc aggctagtgc tcaacttacc caagccaagc
    78241 aggaattggg caaggaagag gataaactaa agcaagctga acaaaatcta gcccaagaaa
    78301 aggaaaaatt agaaaaacat cagcaagtct tggacgattt ggcggagcca aggtatcagg
    78361 tctataatcg tcagaccatg ccaggtggtc agggctatct tatgtatagc aatgcttcat
    78421 ccagtattcg agcagtgggc aatatctttc ctgtggtact ttatgccgta gcatccatgg
    78481 tgacctttac gaccatgact cgctttgtag acgaagagcg aactcatgca gggattttta
    78541 aggccttggg ttaccgtagt aaggatatta tcaccaagtt tctcctttat ggactagtag
    78601 ctgggactgt cggaacggct ctaggtagta tacttggtca ttatttgcta gccagtgtaa
    78661 tttcaagtgt cattacaaaa ggcatggtgg tgggagaaac ccagattcag ttctattgga
    78721 cctatagctt actagctctt gtcttgagct ggttggcgag tgtgttacca gcctatctgg
    78781 tggcttggag ggaacttcat gccgaagcag cccagcttct acttcctaaa cctcctgtca
    78841 aaggagctaa aatcttattg gagcgtatcg gttttatctg gcgtcgtctc agttttactc
    78901 ataaggtaac agcccgcaac atctttcgtt ataagcagag aatgttgatg acaatctttg
    78961 gtgtggcagg ttctgtagct ctgctctttg caggtttggg aatccaatct tctgtagcag
    79021 gagttccgtc taaacagttt caacaaatcc aacagtatca gatgcttgtc tctgaaaatc
    79081 ctagtgcgac caatcaggac aaggtagagc tagcagaagt gttgaaaggg caggagatac
    79141 tagcctacca gaaaatctat tctaaaacgc tagacaagga tttcaaaggc aaggctggtc
    79201 ttcaaaacat tactcttatg atgatagaga aggaagattt gactcccttt atccatcttc
    79261 aacatcatca gcaggagctg acattaaaag atggcatcgt tattacagct aaactcgccc
    79321 agctggcagg tgtcaaggtt gggcagactt tagaaattga aggtaaggaa ctaaaggtcg
    79381 ctgctattac tgagaactac gttggtcact ttatttatat gagtcaggct agctatgagc
    79441 aactttacgg acagctaccc caagccaaca cttatctggt ctcattaagg gataccagtg
    79501 caactagtat cgaaagtcag gcgggcttgc ttatgaatca atctgcggtg tccagcgttg
    79561 tccaaaatgc ttcagccatt cgactctatc gctagctcac tcaatcagac catgaccatc
    79621 ttggtcatcg tatcagttct attagctatt gtcatccttt acaatctgac caatatcaac
    79681 gtagctgaga gaatccgtga actctccact atcaaggttc tcggttttca taataatgaa
    79741 gtcaccctct acatttaccg tgagacgatt gtgctgtccc ttgtgggaat cgtacttggt
    79801 ctggtagctg gtttctattt acaccaattt ttgattcaaa tgatttcgcc tgcgactatt
    79861 ctcttttatc cgcaggtagg ctgggaagtc tatgtaatcc cagtggcaac agtaagcatc
    79921 attttgacct tgcttggttt cttcgtcaat tattatctga gaaaggttga tatgttagaa
    79981 gccctgaaat ctgtagagta aggtagttat ttttagctga ttgaacttct atttactaat
    80041 attcaaaaat cctctgtcac aaagagcagg gagctctttg tgacagagga ttttttctat
    80101 agggctttag cagctgcaat tgcggcttcg aagtttggct cagaattgat attatccacg
    80161 tattcaacgt agcgaatcgt attgtcagta tcgaggacaa agactgcgcg tgctaatagg
    80221 tgccattcgt tgatcaagag ggcataatcg cgcccgaaag aatggtcaaa gtagtctgaa
    80281 agcataatgg cattgtcaag gccttcagca ccgcaccaac gtttttgagc aaaaggtagg
    80341 tccattgaaa cagtcaatac gaccgtgttg tccagtccag ccaattcttc attaaaacga
    80401 cgtgtttgag ttgagcagat gcctgtatcg atagaaggaa cgacactcaa gacttttttc
    80461 ttgccatcaa aatcagccag agatttttta gaaagatctg ttgtagtaag agaaaaatca
    80521 agcgccttgt cgccgacttg tagttgttta cctgtaaagc tcacaggatt tccgagaaaa
    80581 gttaccatag gatactccaa tcttttttct tccattgtat ctgaaacagt cagaattttc
    80641 caatgatttg accggaaatg tgggcataga aaaaacgcca gctcacatga gaatgacgtt
    80701 tttcagaggc ttattttgcc aatccttcag caatcttgtc aaggttgtat ttcatcatgc
    80761 tgtagtagct gtcgccttct ttaccttgtt ctgcgataga gtcagtaaag atttgtgcgt
    80821 agattgggat gtttgtgtct tgagaaacag ttttcattgg acggtcatcc acacttgatt
    80881 ctacaaagag tgatggaact tttgtttggc gaagtttttc aaccaaggtc ttgatttgtt
    80941 caggagttcc ttcttcttca gtattgattt cccagatgta agcacttggg acaccatagg
    81001 ctttagagaa gtatttgaat gctccttcgc tggttacaat gagtttcttt tcagcaggga
    81061 tcttattaaa tttatcctta ctttctttat caagtttgtc taacttatca gtatattctt
    81121 tgagattttt ttcatagaat tctttattgt tagggtcttt ggcgctcaat tgtttggcga
    81181 tatttttagc aaaaataata ccgttttcaa ggttaagcca agcgtgtggg tcttcttttc
    81241 ctttttcatt ttgaccttca aggtagataa catcaacgcc gtcgctgact gcgaagtagt
    81301 ctttgttttc agttttcttg gcattttcta ccaattttgt aaaccaagca ttgccacctg
    81361 tttcaaggtt gataccgtta tagaaaatca aatcagcctc agaagttttc ttaacgtctt
    81421 caggaagtgg ttcgtattcg tgtgggtctt gcccaatcgg aacgatacta tgaaggtcaa
    81481 ttttgtcacc agcaatattt ttagtaatat cagcgatgat tgagtttgta gcaacaactt
    81541 ttagtttttg accagaagtt gtatcttttt ttccgctagc acatgctaca agaatgattg
    81601 cagaaagaaa gagaacgagt aatgtaccta attttttcat tagatcctcc aaattattag
    81661 ggctttgccc cttattttaa caaatgttta tttttcagtt tcaaatatcg ttgtttggga
    81721 gcgataaaga agctaatgag aaagaaacta gcagctgtaa gcacgatact agaacctgcc
    81781 gcaacattaa aactatagcc aataaagagt cccaaaactg aagcagtagc tccgaaggtt
    81841 gaggaaagga aaatcatgct tttcagacta ttagcataca gataagcagt tgcagctggg
    81901 gtaatcagca tggctacaat caggatagtt ccgacacttt gcatggctgt cacagacacg
    81961 agagtcagga gtaccatgag aaggtagtga tagaaattga caggcattcc catggcttta
    82021 gccaagagtt catcaaagga agttatcaag agttgcttga agaaaatcca gattaacaag
    82081 aggatggctg cccccacacc catagtaata aacatatccg tatcttggac ggccaggata
    82141 ttaccaaaaa ggatatggaa aaggtcagtt gaacttttag cgacaccaat caagatgata
    82201 ccgagggcta agaaagaaga aaaggtaatg ccgatggcgg tatcgctttt gataatcgag
    82261 tttcctttga tgtaggtaat gatgatggca gctagcaatc caaagacaat ggctccgata
    82321 aagaagtcaa ggcccaagat gaaggagagg gctacacctg gtaagacagc atgtgaaatg
    82381 gcatctccca tgagtgacat cccgcgtaga ataatgaaac atcccacagc tccagctaca
    82441 atcccgacga caatagctgt tatcaaggca ttttgtagga aatggaattt ttgcaatcca
    82501 tcgataaatt ctgcaatcat aggtcacctc cattgaaaaa gagttgatta ccgtaagctt
    82561 cttttagatt ggtttcggta aaagtttctt ttgttggacc aaaggcaatc acttctcgat
    82621 tgacaagtaa gacttgatcg aagtagtggg gaatcttgct gaggtcgtgg tgaacgatga
    82681 gaaccgtctt cccagctttt ttcaaatctc tcagcgtatt catgatgatt tcctcactga
    82741 cagagtcaat cccagcaaag ggttcatcca agaggatata gtcggcttcc tgcaccaaac
    82801 atctggcaat caaaacccgc tggaattgac ctccagacag ttgactaatt tgacgttcag
    82861 cgtagtcagc taggccgacg atttcaaggg cctcttgcac tttcttccaa tgtttagcct
    82921 ttaaacttcg aaagagagga atagagggaa atagtcctaa cgagacgcat tccttgacct
    82981 tgatgggaaa gttgtagtcg atattgattt tttgttcgac ataggcaatt cggtgtaagg
    83041 attttttaac ttccttgtca tcgagaaatg cctgaccttg atgtgggata attcccagca
    83101 taccttttaa tagtgttgat ttcccagcgc cgtttggacc aatgatgccg gtaattgttg
    83161 gtccatggag cactagtgaa atatccttaa gtgccaacgt ttctttgtag gagacactga
    83221 ggttttcgat acgtatcata aacttgtatt cctcctgtct cttaatatac attaaaaaaa
    83281 aaattaagtc aagttaattt ttgaaaaaat taaaataata actgaaaaat aga
//
LOCUS       DAVBDR010000003        80116 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.003, whole genome shotgun sequence.
ACCESSION   DAVBDR010000003 DAVBDR010000000
VERSION     DAVBDR010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 80116)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 80116)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..80116
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.003"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            complement(134..1882)
                     /locus_tag="VQ540_000175"
     CDS             complement(134..1882)
                     /locus_tag="VQ540_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2544052.1"
                     /translation="MKRQTVNQTLKRLVVDLANHPFLLFLAFLGTIAQVGLSIYLPIL
                     IGQVIDQVLVAGSSPVFWQIFLQMLLVVIGNTLVQWANPLLYNRLIFSYTRDLRERII
                     HKLHRLPIAFADRQGNGEMVSRVTTDIEQLAAGLTMIFNQFFIGVLMILVSILAMLQI
                     HLLMTLLVLLLTPLSMVISRFIAKRSYHLFQKQTETRGIQTQLIEESLSQQTIIQSFN
                     AQTEFIQRLREAHDNYSGYSQSAIFYSSTVNPSTRFVNALIYALLAGVGAYRIMMGST
                     LTVGRLVTFLNYVQQYTKPFNDISSVLAELQSALACVERIYGVLDSPEVAETGKEVLT
                     SDQVKGAISFKHVSFGYHPEKILIKELSIDIPAGSKVAIVGPTGAGKSTLINLLMRFY
                     PISSGDILLDGQSIYDYTRVSLRQQFGMVLQETWLTQGTIHDNIAFGNPEASREQVIA
                     AAKAANADFFIQQLPQGYDTKLENAGESLSVGQAQLLTISRVFLAIPKILILDEATSS
                     IDTRTEVLVQDAFAKLMKGRTSFIIAHRLSTIQDADLILVLVDGDIVEYGNHQELMDR
                     KGKYYQMQKAAAFSSE"
     gene            complement(1884..3608)
                     /locus_tag="VQ540_000176"
     CDS             complement(1884..3608)
                     /locus_tag="VQ540_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2544053.1"
                     /translation="MKHLLSYFKPYIKESILAPLFKLLEAVFELLVPMVIAGIVDQSL
                     PQGDQGHLWMQIGLLLIFAVIGVLVALIAQFYSAKAAVGFAKELTNDLYRHILSLPKD
                     SRDRLTTSSLVTRLTSDTYQIQTGINQFLRLFLRAPIIVFGAIFMAYRISAELTFWFL
                     VMVAILTIVIVGLSRLVNPLYSSLRKKTDQLVQETRQQLQGMRVIRAFGQEKRELQIF
                     QTLNQVYARLQEKTGFLSSLLTPLTYLIVNGTLLVIIWQGYISIQGGVLSQGALIALI
                     NYLLQILVELVKLAMLINSLNQSYISAKRIEEVFAESPENIHSELEQKQVTSGRVLQV
                     QELTFTYPDAAQPSLRDISFDMTQGQILGIIGGTGSGKSSLVQLLLGLYPVDKGNIDL
                     YQNGRSPLNLEQWRSWIAYVPQKVELFKGTIRSNLTLGLNQEVTDQELWQALEIAQAK
                     DFVSDKEGLLDALVEAGGRNFSGGQKQRLSIARAVLRQAPFLILDDATSALDTITESK
                     LLKAIRENLPNMSLILISQRTSTLQMADQILLLEKGELLAVGKHDDLMKSSQVYREIN
                     ASQHGKED"
     gene            complement(3666..4604)
                     /gene="msrB"
                     /locus_tag="VQ540_000177"
     CDS             complement(3666..4604)
                     /gene="msrB"
                     /locus_tag="VQ540_000177"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HET2544054.1"
                     /translation="MAEIYLAGGCFWGLEEYFSRISGVLETSVGYANGQVETTNYQLI
                     KETDHAETVQVIYDEKEVSLREILLYYFRVIDPLSINQQGNDRGRQYRTGIYYQDEAD
                     LPAIYTVVQEQERMLGRKIAVEVEQLRHYILAEDYHQDYLRKNPSGYCHIDVTDADKP
                     LIDAANYEKPSQEVLKASLSEESYRVTQEAATEAPFTNAYDQTFEEGIYVDITTGEPL
                     FFAKDKFASGCGWPSFSRPISKELIHYYKDLSHGMERIEVRSRSGSAHLGHVFTDGPR
                     ELGGLRYCINSASLRFVAKDEMEKAGYGYLLPYLNK"
     gene            complement(4746..4823)
                     /locus_tag="VQ540_000178"
                     /pseudo
     CDS             complement(4746..4823)
                     /locus_tag="VQ540_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(4899..5768)
                     /locus_tag="VQ540_000179"
     CDS             complement(4899..5768)
                     /locus_tag="VQ540_000179"
                     /EC_number="2.7.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000692406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="HET2544055.1"
                     /translation="MKIIVPATSANIGPGFDSVGVAVTKYLQIEVCEERDEWLIEHQI
                     GKWIPHDERNLLLKIALQIVPDLQPRRLKMTSDVPLARGLGSSSSVIVAGIELANQLG
                     QLNLSDHEKLQLATKIEGHPDNVAPAIYGNLVIASSVEGQVSAIVADFPECDFLAYIP
                     NYELRTRDSRSVLPKKLSYKEAVAASSIANVAVAALLAGDMVTAGQAIEGDLFHERYR
                     QDLVREFAMIKQVTKENGAYATYLSGAGPTVMVLASHDKMPTIKAELEKQPFKGKLHD
                     LRVDTKGVRVEAK"
     gene            complement(5770..7056)
                     /locus_tag="VQ540_000180"
     CDS             complement(5770..7056)
                     /locus_tag="VQ540_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HET2544056.1"
                     /translation="MTVKIALLGFGTVASGVPFLLKENGGKINQSAHSDIKVAKVLVK
                     DEDEKNRLLAAGNDFNFVTNVDDILSDQDITIVVELMGRIEPAKTFITRALEAGKHVV
                     TANKDLLAVHGAELLEIAQANKVALYYEAAVAGGIPILRTLANSLASDKITRVLGVVN
                     GTSNFMVTKMVEEGWSYDDALAEAQRLGFAESDPTNDVDGIDAAYKMVILSQFAFGMK
                     IAFDDVAHKGIRNITPEDVAVAQELGYVVKLVGSIEETSSGIAAEVTPTFLPKAHPLA
                     SVNGVMNAVFVESIGIGESMYYGPGAGQKPTATSVVADIVRIVRRLNDGTIGKDFNEY
                     SRDLVLANPEDVKANYYFSILALDSKGQVLKLAEIFNAQDISFKQILQDGKEGDKARV
                     VIITHKINKAQLENVSAELKKVSEFDLLNTFKVLGE"
     gene            complement(7207..7944)
                     /gene="mecA"
                     /locus_tag="VQ540_000181"
     CDS             complement(7207..7944)
                     /gene="mecA"
                     /locus_tag="VQ540_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HET2544057.1"
                     /translation="MKMKQISDTTLKITMSLEDLMDRGMEIADFLVPQEKTEEFFYAI
                     LDELEMPDSFLDTGMLSFRVTPKPDKVDVFVTKSKIDQNLDFEDLSDLPDMEELAQMS
                     PDEFIKTLEKSIADKTKDDIEAIQSLEQVEAKEEEQEQAEQEAESKKEPYIYYILSFA
                     KLADLVAFAKTVTFEMETSELYKMNERYYLTILVDIENHPSPYPAWLLARMREFADDS
                     DISRSVLQEYGQVLMSHDAVLNLQKIG"
     gene            complement(8144..9178)
                     /locus_tag="VQ540_000182"
     CDS             complement(8144..9178)
                     /locus_tag="VQ540_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HET2544058.1"
                     /translation="MFEHYSVADLFANLYKKRKANILALIALFALIAVPFTIKAVRNK
                     NTVKDTTSYSTYLIYKITPPKESAKTILNHQIGGYSDFYGKLIDGNLNGAYLFNDVEP
                     SELKKIASELDTTETTLKNSTNDYWWKKLTVYYMIDDAGVGVKILTSSKDANDLLEKK
                     IDGLIEKFKHAYANVKIEKLETINSKELNANGETALGLNVKNLILRLVVIGVVCVILV
                     VMGNVLVYLFNPTINRVGDFSQYQIDFVTEITTIANLADVLSYKNTGQELTIVSSNKA
                     ILDKLKQSQEALKGMHFVDLQDVSSLLERDTVLLVEEYGVTRYKKFEQSLQILRNLNR
                     SILGVATFKL"
     gene            complement(9207..10640)
                     /locus_tag="VQ540_000183"
     CDS             complement(9207..10640)
                     /locus_tag="VQ540_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen polysaccharide polymerase Wzy family
                     protein"
                     /protein_id="HET2544059.1"
                     /translation="MIDGKRLLFSLTIVSYALTLVSGIVYLFNNNNVSLLSTLLFLLV
                     SSLIACWNDIKYYLIHFIFYLTIFVFLVSRPTIDYFRDGALDTYHPIAYRFAFIVVMV
                     SILGLTTGGILARYFIARKKIKVANIGNSLKEVYIKRLRFVSLGVFLLTYPFYFIRLF
                     ERLLYRLQTSYYAYYANFESKLPYFTYILSTFTVYAMCMYLATKPKKLQATAVLVSFI
                     AANTIHLAIGTRNPFILSILFAFVYYFMREQTEKGKWIGFKEKLAIFVGSPILMLAMG
                     VLNYVRDNVQVSHTGFWDILLDFIYKQGTSFGVLARGFLFNSSLPYRDFRNFTFGPVL
                     DYFARGSLGAIFGGKAFEHTTNSVELAIDSNSYAHNLSYLVLNKEYLKGHGIGSSYIM
                     ELYTDYGMIGVFLLSFLLGVLFIAMLQVAYRSRTILFALSLLILNNLFFMPRSSFSES
                     FFNLFTMQFWGIVLVIIFIAKMLTKEN"
     gene            complement(10656..11642)
                     /locus_tag="VQ540_000184"
     CDS             complement(10656..11642)
                     /locus_tag="VQ540_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000446977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HET2544060.1"
                     /translation="METALISVIVPVYNVAQYLEKSIASIQKQIYQNLEIILVDDGAT
                     DESGRLCDSIAEQDDRVSVLHKKNEGLSQARNDGMKQAHGDYLIFIDSDDYIHPEMIQ
                     SLYEQLVQEDADVSSCGVMNVYANDESPQSANQDDYFVCDSQTFLKEYLIGEKIPGTI
                     CNKLIKRQIATALSFPKGLIYEDAYYHFDLIKLAKKYVVNTKPYYYYFHRGDSITTKP
                     YAEKDLAYIDIYQKFYNEVVKNYPDLKEVAFFRLAYAHFFILDKMLLDDQYKQFEAYS
                     QIHRFLKGHAFAISRNPIFRKGRRISALALFINISLYRFLLLKNIEKSKKLH"
     gene            complement(11644..12747)
                     /locus_tag="VQ540_000185"
     CDS             complement(11644..12747)
                     /locus_tag="VQ540_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000225894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HET2544061.1"
                     /translation="MVAKKKILFFMWSFSLGGGAEKILSTIVSNLDLEKYDIDILEME
                     HFDKGYESVPKHVRILKSLQDYRQTRWLRAFLWRMRIYFPRLTRRLLVKDDYDVEVSF
                     TIMNPPLLFSKRREVKKISWIHGSIEELLKDSSKRESHRSQLDAANTIVGISKKTSNS
                     IKEVYPDYASKLQIIYNGYDFQTILEKSQEKIDIEIAPQSICTIGRIEENKGSDRVVE
                     VIRLLHQEGKNYHLYFIGAGDMEEELKKRVKEYGIEDYVHFLGYQKNPYQYLSQTKVL
                     LSMSKQEGFPGVYVEALSLGLPFISTDVGGAEELSQEGRFGQIIESNQEAAQAITNYM
                     TSASNFDVDEASQFIQQFTITKQIEQVEKLLEE"
     gene            complement(12737..13582)
                     /locus_tag="VQ540_000186"
     CDS             complement(12737..13582)
                     /locus_tag="VQ540_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HET2544062.1"
                     /translation="MNNMTDLKAIQARSLEMAEYFVAFCKEHDLLCYLCGGGAIGALR
                     NKGFIPWDDDLDFFMPRKDYEKLAELWPRYADERYFLSKSHKDFVDRNLFITIRDKET
                     TCIKPYQQDLDLPHGLTLDVLPLDYYPKNPAERKKQVRWALIYSLFCAQTIPEKHGAL
                     MKWGSRILLGLTPKSLRYRIWKKAEKEMTKYDLADCDGITELCSGPGYMRNKYPITSF
                     EDNLFLPFEGTEMPIPIGYDVYLRTAFGDYMTPPPADKQVPHHDAVIADMDKSYTEYK
                     GEYGG"
     gene            complement(13861..15135)
                     /gene="psr"
                     /locus_tag="VQ540_000187"
     CDS             complement(13861..15135)
                     /gene="psr"
                     /locus_tag="VQ540_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyisoprenyl-teichoic acid--peptidoglycan
                     teichoic acid transferase Psr"
                     /protein_id="HET2544063.1"
                     /translation="MSKENPLSHHEQLRYDYLLKNIHYLNEREKNEFAYLQEKLTLAR
                     GNSSSSLEQEREEQVDLPSYANRSRSQSKSQALSFPPKKKRRKLRLKRIFMVIFSLLV
                     CVALAMVFMFLRGYQDASAKKTADARAAQVEVFNGQDTRDGVNILIMGTDGRIGQNSV
                     ETRTDSIMVLNVGGSDKKMKLVSFMRDNLVYIDGYSQVINGRKQTDNKLNVAYELGEQ
                     EGQKGAEMVRQVLKDNFDLDIKYYALVDFQAFATAIDTLFPDGVTIDAQFSTLNGRPL
                     TEATVGDDLYATETESPTQTIKVGKQQMNGSTLLNYARFRDDDEADYGRTKRQQQVLT
                     AILEQIKDPTKLFTGSEALGKVFAMTSTNVPYTFLLTNGLSVLDGAKNGIEKLTIPEL
                     GDWVDAYDVYGGLGLLVDQNKYQTKLAQMGLR"
     gene            complement(15132..15980)
                     /gene="pheA"
                     /locus_tag="VQ540_000188"
     CDS             complement(15132..15980)
                     /gene="pheA"
                     /locus_tag="VQ540_000188"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HET2544064.1"
                     /translation="MKIAYLGPKGSFSHHVVQTAFPHEELQAFANITDVIKAYEQGLV
                     DYSVVPVENSIEGSVHETLDYLFHQAHIQAVAEIVQPIHQQLMVVPGHTKIEKIFSHP
                     QALAQGKKFIDEQYPEAQIEVTASTAYAARFISEHPDQPFAAVAPRSSAEEYGLELIA
                     EDIQEMEANFTRFWVLGAEKPSIPLQAQTEKMSLALTLPDNLPGALYKALSTFAWRGI
                     DLTKIESRPLKTALGEYFFIIDVDYIDKDLVHFAQKELEAIGIQYKILGAYPIYPISD
                     HGKERR"
     gene            complement(15977..16453)
                     /locus_tag="VQ540_000189"
     CDS             complement(15977..16453)
                     /locus_tag="VQ540_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HET2544065.1"
                     /translation="MAKVLLGFMGAGKSTIARGLDPNYLDMDALIEKRLGMSIANFFA
                     EKGEAAFRHVESEVLADLLQTDQVVSTGGGVVISQRNRDLLKTNTDNIYLKADFETLY
                     LRIAADKDNQRPLFLNNSKEELVAIFQERQAWYEEVASRVLDVTKLSPEEIIEELR"
     gene            complement(16446..17729)
                     /gene="aroA"
                     /locus_tag="VQ540_000190"
     CDS             complement(16446..17729)
                     /gene="aroA"
                     /locus_tag="VQ540_000190"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004236106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HET2544066.1"
                     /translation="MKLKTNIRHLHGSIRVPGDKSISHRSIIFGSLAEGETKVYDILR
                     GEDVLSTMQVFRDLGVEIEDKDGVITIQGVGMAGLKAPQNALNMGNSGTSIRLISGVL
                     AGADFEVEMFGDDSLSKRPMDRVTLPLKKMGVSISGQTERDLPPLRLKGTKNLRPIHY
                     ELPIASAQVKSALMFAALQAKGESVIIEKEYTRNHTEDMLQQFGGHLSVDGKKITVQG
                     PQKLTGQKVVVPGDISSAAFWLVAGLIAPNSRLVLQNVGINETRTGIIDVIRAMGGKL
                     EITEIDPVAKSATLIVESSDLKGTEIGGALIPRLIDELPIIALLATQAQGVTVIKDAE
                     ELKVKETDRIQVVADALNSMGADITPTADGMIIKGKSALHGARVNTFGDHRIGMMTAI
                     AALLVADGEVELDRAEAINTSYPSFFDDLESLIHG"
     gene            complement(17821..18159)
                     /locus_tag="VQ540_000191"
     CDS             complement(17821..18159)
                     /locus_tag="VQ540_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF/YmcA family competence regulator"
                     /protein_id="HET2544067.1"
                     /translation="MSNIYDSANELSRGLRGLPEYKAVKAAKDAIAADAEASKIFTEY
                     LAFQEEIQKLAQTGQMPDASFQAKMEGFGKQIQGNSLLSEFFTKQQQLAIYLSDIEKI
                     VFEPVSELLK"
     gene            complement(18170..19273)
                     /locus_tag="VQ540_000192"
     CDS             complement(18170..19273)
                     /locus_tag="VQ540_000192"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HET2544068.1"
                     /translation="MAKTIYIAGLGLIGASMALGIKRDHPDYEILGYNRSQASRDIAL
                     KEGMIDRATDDFASFAPLADVIILSLPIKQTIAFIKELANLDLREGVIISDAGSTKST
                     IVDAAEQYLAGKSVRFVGAHPMAGSHKTGAASADVNLFENAYYIFTPSSLTSQDTLKE
                     MKDLLSGLHARFIEIDAKEHDRVTSQISHFPHILASSLMEQTAVYAQEHEMARRFAAG
                     GFRDMTRIAESEPGMWTSILLSNSETILDRIEDFKERLEVIGQAISKGDEEQIWNFFN
                     QAREQRQTMEIHKRGGVDSSYDLYVDVPDEEDVILRILELLRGTSLVNIHINEENRED
                     IHGILQISFKNAQDLERAEHLITENTDYTVVIK"
     gene            complement(19283..20449)
                     /gene="aroC"
                     /locus_tag="VQ540_000193"
     CDS             complement(19283..20449)
                     /gene="aroC"
                     /locus_tag="VQ540_000193"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HET2544069.1"
                     /translation="MRYLTAGESHGPRLTAIIEGIPAGLPLTAEDINEDLRRRQGGYG
                     RGGRMKIESDQVVFTSGVRHGKTTGAPITMDVINKDHQKWLDIMSAEDIEDRLKSKRK
                     ITHPRPGHADLVGGIKYRFDDLRNSLERSSARETTMRVAVGAVAKRLLAELDMEIANH
                     VVVFGGKEIDVPENLTVAEIKQRAAQSEVSIVNQEREQEIKDYIDQIKRDGDTIGGVV
                     ETVVGGVPVGLGSYVQWDRKLDARLAQAVVSINAFKGVEFGLGFEAGYRKGSQVMDEI
                     LWSKEDGYTRRTNNLGGFEGGMTNGQPIVVRGVMKPIPTLYKPLMSVDIETHEPYKAT
                     VERSDPTALPAAGMVMEAVVATVLAQEILEKFSSDNLEELKEAVAKHRDYTKNY"
     gene            complement(20459..21526)
                     /locus_tag="VQ540_000194"
     CDS             complement(20459..21526)
                     /locus_tag="VQ540_000194"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HET2544070.1"
                     /translation="MKIRIDIPHHPYDIQIEKGCMAQAGQWLRELWQPQKVVIVTDNH
                     VASLYAEKVKLSLEDAGFQVAVFDFLEGEERKNLTTVQKVYEFLVKQGLTRSDGIVAL
                     GGGVVGDLAGFVASTYMRGIHFVQIPTSLTAQVDSSIGGKTGVNTPFAKNMVGTFAQP
                     DGVLIDPLVLETLGKRELIEGMGEVIKYGLIEDPELWALLTGLNGSVESILEHAETLI
                     EHSCQVKRKMVVEDELDNGIRLYLNFGHTIGHAIEATAGYGKVMHGEAVAMGMVQISK
                     VAEEKGLMPAGITQSITEMCQKFGLPVDYENWKVDKLYQALTHDKKARGNTLKLVLVP
                     ELGSATIHPVSLEEMKDYLVK"
     gene            complement(21545..22399)
                     /locus_tag="VQ540_000195"
     CDS             complement(21545..22399)
                     /locus_tag="VQ540_000195"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HET2544071.1"
                     /translation="MKLDGYTRLAAVVANPIKHSISPFIHNRAFEATATNGAYVAWEI
                     EASDLVETVANIRRYQMFGINLSMPYKEQVIPYLDELSDEARLIGAVNTVVNENGNLI
                     GYNTDGKGFFKCLPSFTISGKKMTLLGAGGAAKSILAQAILDGVSQISVFVRSVSMEK
                     TRPYLDKLQEQTGFKVDLCALEYVSELQARIAESDLLVNATSVGMDGQSSPVPENIVL
                     PETLLVADIIYQPFETPFLKWARSQGNPAVNGLGMLLYQAAEAFQLWTGKKMPTEEIW
                     QSLTEKYQ"
     gene            complement(22389..23066)
                     /locus_tag="VQ540_000196"
     CDS             complement(22389..23066)
                     /locus_tag="VQ540_000196"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HET2544072.1"
                     /translation="MKLIVSVMPRSLEEAQALDATRYLDADIIEWRADYLPKEAILQV
                     APAIFEKFAGRELVFTLRTRSEGGEIDLSPEEYIHLIKEVAQLYQPDYIDFEYYSYKD
                     VFEEMLDFPNLVLSYHNFQETPENMMEILSELTILNPKLVKVAVMAHTEQDVLDLMNY
                     TRGFKTLNPEQEYVTISMGKVGKVSRITADVTGSSWSFASLDEVSAPGQISLASMKKI
                     REILDEA"
     gene            complement(23063..24226)
                     /locus_tag="VQ540_000197"
     CDS             complement(23063..24226)
                     /locus_tag="VQ540_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HET2544073.1"
                     /translation="MNRIRVSKRVEKKLAKGLVLLEASDLENVNLKDQEVEVQGQEGN
                     FLGTAYLSQQNKGLGWFVSKDKVAFNQAFFETLFRKAKEKRNAYYQDDLTTAFRLFNQ
                     EGDGFGGLTVDLYGDYAVFSWYNSYVYQIRQTISEAFRQVFPEVLGAYEKIRFKGLDY
                     ESAHVYGQEAPDFFTVLENGVLYQVFMNDGLMTGIFLDQHEVRGSLVDGLAMGKSLLN
                     MFSYTAAFSVAAAMGGASQTTSVDLAKRSRELSQAHFQANGLSTDERRFIVMDVFEYF
                     KYAKRKNLTYDVIVLDPPSFARNKKQTFSVAKDYHKLISQSLEILNPGGIIIASTNAA
                     NVSRQKFTEQIDKGFAGRSYQILNKYGLPADFAYNKKDESSNYLKVISMKVSK"
     gene            complement(24911..26545)
                     /locus_tag="VQ540_000198"
                     /pseudo
     CDS             complement(24911..26545)
                     /locus_tag="VQ540_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001237556.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(26526..27275)
                     /locus_tag="VQ540_000199"
     CDS             complement(26526..27275)
                     /locus_tag="VQ540_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2544074.1"
                     /translation="MIEFQNVSKLYGDKEALSNLNLQIENGEIMGLIGHNGAGKSTTI
                     KSLVSIISPSSGRILVDGQELSENRLAIKRKIGYVADSPDLFLRLTANEFWELIASSY
                     DLTSSDLETSLARLLNVFDFAENRYQVIETLSHGMRQKVFVIGALLSAPDIWVLDEPL
                     TGLDPQAAFDLKQMMKEHAQKGKTVLFSTHVLEVAEQVCDRIAILKKGHLIYCGSVEN
                     LRKDHPDQFLESIYLSLAGRKEEVADASQGH"
     gene            27454..28908
                     /locus_tag="VQ540_000200"
     CDS             27454..28908
                     /locus_tag="VQ540_000200"
                     /EC_number="3.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase"
                     /protein_id="HET2544075.1"
                     /translation="MQNQTLMQYFEWYLPHDGQHWTRLAENAPHLAHLGISHVWMPPA
                     FKATNEKDVGYGVYDLFDLGEFNQKGTVRTKYGFKEDYLQAIQALKEQGIQPMADVVL
                     NHKAAADNREAFQVIEVDPVDRTVELGEPFTINGWTSFTFDGRQDTYNGFHWHWYHFT
                     GTDYDAKRSKSGIYLIQGDNKGWANEELVDNENGNYDYLMYADLDFKHPEVIQNIYDW
                     ADWFMETTGVAGFRLDAVKHIDSFFMRNFIRDMKEKYGDDFYVFGEFWNPDKEANLDY
                     LEKTEEHFDLVDVRLHQNLFEASQAGANYDLRGIFTDSLVELKPDKAVTFVDNHDTQR
                     GQALESTVEEWFKPAAYALILLRQDGLPCVFYGDYYGISGQYAQEDFKEILDRLLAIR
                     KDLAYGEQNDYFDHANCIGWVRSGAENQSPIAVLISNDQENSKSMFVGQEWTNQTFVD
                     LLGNHQGQVTIDEEGYGQFPVSARSVSVWAVNTI"
     gene            complement(28998..31616)
                     /gene="alaS"
                     /locus_tag="VQ540_000201"
     CDS             complement(28998..31616)
                     /gene="alaS"
                     /locus_tag="VQ540_000201"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HET2544076.1"
                     /translation="MKQLSSAQVRQMWLDFWATKGHSVEPSVSLVPVNDPTLLWINSG
                     VATLKKYFDGTIIPENPRITNAQKAIRTNDIENVGKTARHHTMFEMLGNFSIGDYFRD
                     EAITWAYELLISPEWFDFPAEKLYMTYYPDDKDSYNRWIEVGVDPSHLIPIEDNFWEI
                     GAGPSGPDTEIFFDRGEAFDPENIGLRLLAEDIENDRYIEIWNIVLSQFNADPAVPRS
                     EYKELPHKNIDTGAGLERLVAVIQGAKTNFETDLFMPIIREVEKLSGKVYDQDGDNMS
                     FKVIADHIRSLSFAIGDGALPGNEGRGYVLRRLLRRASMHGQKLGINEPFLYKLVPTV
                     GKIMESYYPEVLEKRDFIEKIVKSEEESFARTLHSGQHFAQGIVADLKEKGQSVIAGS
                     DVFKLYDTYGFPVELTEEIAEEAGMTVDREGFEAAMKEQQERARASAVKGGSMGMQNE
                     TLQNITVESVFNYNTSQLSSKLVAIVADNAEVGAVSEGTASLIFAETSFYAEMGGQVA
                     DYGQILDESGKIVATVTNVQKAPNGQALHTVEVLAPLALNQEYTLAIDSNRRHRVMKN
                     HTATHLLHAALHNILGNHATQAGSLNEVEFLRFDFTHFQAVTAEELRAIEQQVNEKIW
                     EALEVKTVETDIDTAKEMGAMALFGEKYGKEVRVVTIGDYSIELCGGTHVGNTSEIGL
                     FKIVKEEGIGSGTRRILAVTGKEAFEAYREQEDALKAVAATLKAPQVKEVPHKVEGLQ
                     EQLRQLQKENAELKEKAAAAAAGDIFKDAKEVNGHRYIASQVSVSDAGALRTFADNWK
                     QKDYSDLLVLVAAIGDKVNVLVASKTKDLHAGNLVKELAPIIDGRGGGKPDMAMAGGS
                     NQAKIQELLDAVAGKL"
     gene            complement(31638..32123)
                     /locus_tag="VQ540_000202"
     CDS             complement(31638..32123)
                     /locus_tag="VQ540_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000847073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LURP-one-related family protein"
                     /protein_id="HET2544077.1"
                     /translation="MKTFLVKQKFRLGGERFAIKDDRGEIAYQVEGSFFKIPKTFTIY
                     DAAGEQVSQISKEILTLLPRFEIQLLDGSSFVIRKKLTFWRDKYEFDNLGLRIEGNIW
                     DLNFKLLDDRDQLIAEIKKELFHLTSTYTVTVLEDAYADLVISLCVAIDYVEMLESQS
                     H"
     gene            complement(32398..32637)
                     /locus_tag="VQ540_000203"
     CDS             complement(32398..32637)
                     /locus_tag="VQ540_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000784186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2544078.1"
                     /translation="MKMSTFFNKSFWPTFMIVNQTAILFHLKDGLDRQYLTTESIYWV
                     IGTFIFGNILVAVFSNMKIWDKKKNGSKKKYILEK"
     gene            complement(32890..33960)
                     /locus_tag="VQ540_000204"
     CDS             complement(32890..33960)
                     /locus_tag="VQ540_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HET2544079.1"
                     /translation="MKKIYSFLAGIAAIILVLWGIATHLDSKINSRDSQKLVIYNWGD
                     YIDPELLTQFTEETGIQVQYETFDSNEAMYTKIKQGGTTYDIAIPSEYMINKMKDEDL
                     LVPLDYSKIEGIENIGPEFLNQSFDPGNKFSIPYFWGTLGIVYNETMVDEAPEHWDDL
                     WKPEYKNSIMLFDGAREVLGLGLNSLGYSLNSKDLQQLEETVDKLYKLTPNIKAIVAD
                     EMKGYMIQNNVAIGVTFSGEASQMLEKNENLRYVVPTEASNLWFDNMVIPKTVKNQDS
                     AYAFINFMLKPENALQNAEYVGYSTPNIPAKELLPEETKEDKAFYPDVETMKHLEIYE
                     KFDHKWTGKYSDLFLQFKMYRK"
     gene            complement(33957..34730)
                     /locus_tag="VQ540_000205"
     CDS             complement(33957..34730)
                     /locus_tag="VQ540_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2544080.1"
                     /translation="MKKFANLYLGLVFLVLYLPIFYLIGYAFNAGDDMNSFTGFSWTH
                     FETMFGDGRLMLILAQTFFLAFLSALIATIIGTFGAIYIYQSRKKYQEAFLSLNNILM
                     VAPDVMIGASFLILFTQLKFSLGFLTVLSSHVAFSIPIVVLMVLPRLKEMNGDMIHAA
                     YDLGASQFQMFKEIMLPYLTPSIITGYFMAFTYSLDDFAVTFFVTGNGFSTLSVEIYS
                     RARKGISLEINALSALVFLFSIILVVGYYFISREKEEQA"
     gene            complement(34727..35533)
                     /locus_tag="VQ540_000206"
     CDS             complement(34727..35533)
                     /locus_tag="VQ540_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2544081.1"
                     /translation="MKKTSSKLFVVPYMLWIALFVLAPLVLIFGQSFFNIEGQFSLEN
                     YKSYFASQNLTYLKMSFNSVLYAGIVTFVTLLISYPTALFLTRLKHRQLWLMLIILPT
                     WINLLLKAYAFIGIFGQNGSINQFLEFIGIGSQQLLFTDFSFIFVASYIELPFMILPI
                     FNVLDDMDNNLINASYDLGATKWETFRHVIFPLSMNGVRSGVQSVFIPSLSLFMLTRL
                     IGGNRVITLGTAIEQNFLTNDNYGMGSTIGVILILTMFITMWVTKERRER"
     gene            complement(35514..36671)
                     /locus_tag="VQ540_000207"
     CDS             complement(35514..36671)
                     /locus_tag="VQ540_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018372333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2544082.1"
                     /translation="MKKPIIEFKNVSKVFEDSNTKVLKDINFELEEGKFYTLLGASGS
                     GKSTILNIIAGLLDATTGDIMLDGVRINDIPTNKRDVHTVFQSYALFPHMNVFENVAF
                     PLRLRKIDKKEIEQRVAEVLKMVQLEGYEKRSIRKLSGGQRQRVAIARAIINQPRVVL
                     LDEPLSALDLKLRTDMQYELRELQQRLGITFVFVTHDQEEALAMSDWIFVMNDGEIVQ
                     SGTPVDIYDEPINHFVATFIGESNILPGTMIEDYLVEFNGKRFEAVDGGMKPNEPVEV
                     VIRPEDLRITLPEEGKLQVKVDTQLFRGVHYEIIAYDELGNEWMIHSTRKAIVGEEIG
                     LDFESEDIHIMRLNETEEEFDARIEEYVEIEEQEAGLINAIEEERDEENKL"
     gene            complement(36730..37680)
                     /gene="murB"
                     /locus_tag="VQ540_000208"
     CDS             complement(36730..37680)
                     /gene="murB"
                     /locus_tag="VQ540_000208"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000116191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HET2544083.1"
                     /translation="MSVREKMLEILEGIDIRFQEPLHSYSYTKVGGEADYLVFPRNRF
                     ELARLVKFANQENIPWMVLGNASNIIVRDGGIRGFVILCDKLNNVSVDGYTIEAEAGA
                     NLIETTRIALRHSLTGFEFACGIPGSVGGAVFMNAGAYGGEIAHILQSCKVLTKDGEI
                     ETLSAKDLAFGYRHSAIQESGAVVLSVKFALAPGTHQVIKQEMDRLTHLRELKQPLEY
                     PSCGSVFKRPVGHFAGQLISEAGLKGYRIGGVEVSEKHAGFMINVADGTAKDYEDLIQ
                     SVIEKVKEHSGITLEREVRILGESLSVAKMYAGGFTPCKR"
     gene            complement(37792..38544)
                     /locus_tag="VQ540_000209"
     CDS             complement(37792..38544)
                     /locus_tag="VQ540_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhfC family intramembrane metalloprotease"
                     /protein_id="HET2544084.1"
                     /translation="MTIHIIITMLLLLAFLIGSIWFAKKKYQINLAVLGLGAVAFFVS
                     SQILEKLVHILILHPQKDGSIALLQDHPLIYIIYGLAMAAFFEETARLVFFKWFEKKR
                     SLEKADALAYGLGHGGLELIFLGLTSLLNLYIVLSAVQTQNPQVMQLLSENMLKTIQS
                     LSVWQIYLLGFERILALGFQLLLTVWVYQAVRQKKWIYLLTAYGLHAFFDLAPSLFQV
                     GWLTNPVLVEVILALELVLVAYGTKEIFCKKS"
     gene            complement(38554..39285)
                     /gene="budA"
                     /locus_tag="VQ540_000210"
     CDS             complement(38554..39285)
                     /gene="budA"
                     /locus_tag="VQ540_000210"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HET2544085.1"
                     /translation="MDKNVQEPVKLFQYNTLGALMAGLYGGTMTVGELLEHGDLGLGT
                     LDSIDGELIVLDGKAYQAKGSGDQPEIVEVSPDALIPYAAVVPHQAEVIFRQRFEMTD
                     KELKERIESYYDGENLFRSIKIRGEFLHMHVRMIPKSTPDTKFADVATHQPEYSRDNV
                     AGTIVGFWTPEIFHGVSVAGYHLHFISDDLTFGGHVMDFVIKEGIIEVGAVDQLDQRF
                     PVQDRQYLFAKFNVDEMKKDIEKAE"
     gene            39427..40698
                     /locus_tag="VQ540_000211"
     CDS             39427..40698
                     /locus_tag="VQ540_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HET2544086.1"
                     /translation="MKKQSKYKEVVSYLKNGIESGRFPTGSRLPSIRQLSLDFHCSKD
                     TIQRALLELRHEQYLYAKPQSGYYVLEQGQHQDLEIEVTDEHASAYDDFRLCVNETLI
                     GRENYLFNYYDNQEGLEDLRQSIHKLLFEQALYCKANQLVLTSGTQQALFILSQISFP
                     RQAKEILVEQPTYHRMNRLLIAQGLDYQTIERGIDGIDLEELEGHFKTGKIKFFYTIP
                     RFHYPLGHSYSEQDKRSILNLAAKYDVYIVEDDYLGDLDSKKGQTFHYLDTEEHVIYI
                     KSFSTSLFPALRITALILPNAIKEAFVAYKNILDYDSNLIMQKALSLYIDSQLFEKNR
                     LARLTNHESYQKQIEERITKTPCPLPHYPLHDGLLLDLRQYPKIASLKHSQLGLDFFE
                     EAYLSTCPYQFAKVSLDNLENVLNYLKAELE"
     gene            complement(40718..41533)
                     /locus_tag="VQ540_000212"
     CDS             complement(40718..41533)
                     /locus_tag="VQ540_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HET2544087.1"
                     /translation="MKSKKWIFVLCNFLASFFLVACQSGSNGSQSAVEAIKQKGKLVV
                     ATSPDYAPFEFQSLVDGKNQVVGADIDMAQAIADELGVKLEILSMSFDNVLTSLQTGK
                     ADLAVAGISATDERKEVFDFSIPYYENKISFLVRKADVEKYKDLTSLESANIAAQKGT
                     VPESMVKEQLPKAQLTSLTNMGEAVNELQAGKIDAVHMDEPVALSYAAKNAGLAVATV
                     SLKMKDGDANAVALRKNSDDLKEVVDKVIQKLKDEGTYQSYLEKAASLTEVEE"
     gene            complement(41690..42343)
                     /gene="phoU"
                     /locus_tag="VQ540_000213"
     CDS             complement(41690..42343)
                     /gene="phoU"
                     /locus_tag="VQ540_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000946475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HET2544088.1"
                     /translation="MLRSQFEEDLEKLHNQFYAMGQEVLSQINRTVRAFVTHDRDLAK
                     EVIEDDAEVNEYEVKLEKKSFEMIALQQPVSQDLRTVLTVLKAVSDVERMGDHAVAIA
                     QATIRMKGEERIPAVEEEIKKMGREVKSVVEAALDLYLNGSVDDAYRVASMDEQINHY
                     FETIRDLATEEIKKNPEAIVTGRDYFQVISYLERIGDYAKNICEWVVYFETGKIVEL"
     gene            complement(42355..43113)
                     /gene="pstB"
                     /locus_tag="VQ540_000214"
     CDS             complement(42355..43113)
                     /gene="pstB"
                     /locus_tag="VQ540_000214"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HET2544089.1"
                     /translation="MTDAILQVSDLSVYYNKKKALNSVSLSFQPKEITALIGPSGSGK
                     STLLKSLNRMGDLNPEVTTTGSVVYNGHNIYSPRTDTVELRKEIGMVFQQPNPFPMTI
                     YENVVYGLRINGIKDKQVLDEAVEKALQGASIWDEVKDRLYDSAIGLSGGQQQRVCVA
                     RVLATSPKIILLDEPTSALDPISAGKIEETLYGLKDKYTMLLVTRSMQQASRISDKTG
                     FFLDGDLIEFNDTKQMFLDPQHKETEDYITGKFG"
     gene            complement(43126..43929)
                     /gene="pstB"
                     /locus_tag="VQ540_000215"
     CDS             complement(43126..43929)
                     /gene="pstB"
                     /locus_tag="VQ540_000215"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HET2544090.1"
                     /translation="MSTYNWDEKHILTFPEEKVALSTKDVHVYYGKNESIKGIDMQFE
                     RNKITALIGPSGSGKSTYLRSLNRMNDTIDIAKVTGQILYRGIDVNRPEINVYEMRKH
                     IGMVFQRPNPFAKSIYRNITFAHERAGVKDKQVLDEIVETSLRQAALWDQVKDDLHKS
                     ALTLSGGQQQRLCIARAISVKPDILLMDEPASALDPIATMQLEETMFELKKNFTIIIV
                     THNMQQAARASDYTGFFYLGDLIEYDKTATIFQNAKLQSTNDYVSGHFG"
     gene            complement(43940..44824)
                     /gene="pstA"
                     /locus_tag="VQ540_000216"
     CDS             complement(43940..44824)
                     /gene="pstA"
                     /locus_tag="VQ540_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009443446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HET2544091.1"
                     /translation="MRAKKLDKLATAVLYTIASIIVTILASLILYILVRGLPHISWSF
                     LTGRSSAFQAGGGIGIQLYNSFFLLVITLIISVPLSMGAGIYLAEYAKKGPVTNFVRT
                     CIEILSSLPSVVVGLFGYLIFVVQFEYGFSIISGALALTVFNLPQMTRNVEDSLKHVH
                     HTQREAGLALGISRWETVVHVVIPEALPGIVTGVVLASGRIFGEAAALIYTAGQSAPA
                     LDWSNWNILSVTSPISIFRQAETLAVHIWKVNSEGTIPDGTIVSAGSAAVLLIFILIF
                     NFGARKFGSYLHKKLTAA"
     gene            complement(44814..45731)
                     /gene="pstC"
                     /locus_tag="VQ540_000217"
     CDS             complement(44814..45731)
                     /gene="pstC"
                     /locus_tag="VQ540_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018378778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HET2544092.1"
                     /translation="MNQEELAKKMLLPSKNSRLEKLGKGLTFACLSLIVILVAMILVF
                     VAQKGLSTFFVNGVNIFDFLLGGTWNPSSKEFGALPMILGSFIVTILSALIATPFAIG
                     AAVFMTEVSPKGAKILQPAIELLVGIPSVVYGFIGLQVVVPFVRSVFGGTGFGILSGI
                     SVLFVMILPTVTFMTTDSLRAVPRYYREASFAMGATRWQTIWRVILKAARSGIFTAVV
                     FGMARAFGEALAIQMVVGNSAVIPTSLTTPAATLTSILTMGIGNTVMGTVNNNVLWSL
                     ALVLLLMSLVFNSVIKLITKERGKKNYAR"
     gene            complement(45731..46609)
                     /gene="pstS"
                     /locus_tag="VQ540_000218"
     CDS             complement(45731..46609)
                     /gene="pstS"
                     /locus_tag="VQ540_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HET2544093.1"
                     /translation="MKKRKKLALSLIAFWLTACLVGCASWIDRGESITAVGSTALQPL
                     VEVAADEFGTIHVGKTVNVQGGGSGTGLSQVQSGAVDIGNSDVFAEEKDGIDASALVD
                     HKVAVAGLALIVNKEVDVDNLTTEQLRQIFIGEVTNWKEVGGKDLPISVINRAAGSGS
                     RATFDTVIMEGQSAMQSQEQDSNGAVKSIVSKSPGAISYLSLTYIDDSVKSMKLNGYD
                     LSPENISSNNWPLWSYEHMYTLGQPNELAAEFLNFVLSDETQEGIVKGLKYIPIKEMK
                     VEKDAAGTVTVLEGRQ"
     gene            complement(47183..48487)
                     /locus_tag="VQ540_000219"
     CDS             complement(47183..48487)
                     /locus_tag="VQ540_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001160253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmF rRNA methyltransferase first C-terminal
                     domain-containing protein"
                     /protein_id="HET2544094.1"
                     /translation="MKFPEGFVEKYKEILGDEARDFLASFEEEAVSAFRVNPLKEEQL
                     SFSDAITQTPWGHYGKVSGKSPEHATGLVYSQEPAAQMVAQVAQPSPGMKVLDLAAAP
                     GGKSTQLAAYLAGEGLLVSNEISSKRAKILVENMERFGATNVVVTNESADRLVKVFKG
                     YFDLIVLDAPCSGEGMFRKQPDAMDYWSLDYPSQCASLQREILEDAVTMLAEGGRLVY
                     STCTWAPEENEEIVNWLLEEYDFDLLPVEHINGMVAGIDLPETARMYPHQFKGEGQFV
                     AHLQFKGNNPAPKFKASKSNLSREQVALWQEFAQNHLKVNLPGILQIFGDQLYLLPEL
                     LPDLGKLKIARNGLHLGTFKKKRFEPSFALGLALKPSQVEQSVEIGQEEFVKYAAGET
                     VQLAESLPNGWYQVLVKGNGLGFAKVTGNVLKNYFPKGLRFK"
     gene            complement(48488..49261)
                     /locus_tag="VQ540_000220"
     CDS             complement(48488..49261)
                     /locus_tag="VQ540_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HET2544095.1"
                     /translation="MKSKFEFAKELVKKAGQYILDHMQEDLRVETKSSPTDLVTRLDK
                     EVQELLVGEILSRYPEDKICAEEGCLRASVQEGKVWVIDPIDGTNNFVAQQEDFAVMM
                     AYFENGQGQFGLIYDVVKGDCYHGGGEFPVCLNDRPLASFKTKPLGDFLIAGNSGMLE
                     TNEWGLADLSRAVLGVRVYGSAAISFAKILSGRLLTYLTYLQPWDYAAASILGESLGY
                     RVVTLFGEAPDFQTRQPVMMVPLEMQEEIQSYIYERKRT"
     gene            complement(49251..49529)
                     /locus_tag="VQ540_000221"
     CDS             complement(49251..49529)
                     /locus_tag="VQ540_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002895777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HET2544096.1"
                     /translation="MNKQYSYPLDLSWSTEELASVLSFFNDVEAAYEGKVEAKKLLDS
                     YKGFKAVVPSKSEEKRLGREFETVSGYSLYRAVQAAKEKGKGKISLEK"
     gene            complement(49529..49930)
                     /locus_tag="VQ540_000222"
     CDS             complement(49529..49930)
                     /locus_tag="VQ540_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007556665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HET2544097.1"
                     /translation="MITLFLSPSCTSCRKAKTWLEKHKVPFVEHNIMTSPLTRKELQH
                     ILSLTENGTDDIISTRSKIFQKLNIDVESISVSELLHLIEQYPSLLRRPIIIDAKRMQ
                     IGFNEDEIRAFLPRSYRKQELKEARMRAGIS"
     gene            complement(50140..50757)
                     /locus_tag="VQ540_000223"
     CDS             complement(50140..50757)
                     /locus_tag="VQ540_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HET2544098.1"
                     /translation="MKTKLTFWGSMLFLLSLSILLTIYLAWIFYPMEIQWLNLTNRVY
                     LKPETIQYNFHILMNYLTNPFSQVLQMPDFRSSAAGLHHFAVVKNLFHLVQLVALVTL
                     PSFYVFVNRIVKKDFLSLYRKSLLALVVLPVMIGLGGVLIGFDQFFTLFHQILFVGDD
                     TWLFDPAKDPVIMILPETFFLHAFLLFFALYESFFGYLCLKSRRK"
     gene            complement(50747..51520)
                     /locus_tag="VQ540_000224"
     CDS             complement(50747..51520)
                     /locus_tag="VQ540_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HET2544099.1"
                     /translation="MKYKGYLIDLDGTIYKGKDQIPAGETFVHELQKRDIPYLFVTNN
                     TTRTPESVKEMLAQNFNIDTPLSTVYTATLATIDYMNDLGLEKTVYVVGEAGLKEAIK
                     AAGYVEDKEKPAYVVVGLDWQVDYEKFATATLAIQKGAHFIGTNPDLNIPTERGLLPG
                     AGSLITLLEVATRVKPVYIGKPNAIIMDKAVEHLGLEREELIMVGDNYLTDIRAGIDN
                     GIPTLLVTTGFTKAEEVAGLPIAPTHVVSSLAEWDFDEN"
     gene            complement(51531..52268)
                     /locus_tag="VQ540_000225"
     CDS             complement(51531..52268)
                     /locus_tag="VQ540_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000524807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HET2544100.1"
                     /translation="MGLTYQMKMKIPFDMADMNGHIKLPDVILLSLQVSGMQSIELGV
                     SDKAILEDYNLVWIIVEYDIEVVRLPRFAEEITIETEALSYNRLFCYRRFTIYNEAGQ
                     ELIHMMATFVLMDRDSRKVHAVEPEIVAPYQSDFDKKLIRGPKYESLEESISKDYHVR
                     FYDLDMNGHVNNSKYLDWIFEVMGADFLTHYIPKKINLKYVKEVRPGGVITSAVERTG
                     LESKHEITSDGVINAQAIITWQEIKKA"
     gene            complement(52273..53403)
                     /locus_tag="VQ540_000226"
     CDS             complement(52273..53403)
                     /locus_tag="VQ540_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HET2544101.1"
                     /translation="MQKKPTSAYVHIPFCTQICYYCDFSKVFIKNQPVDSYLEHLLEE
                     FRSYDIEKLSTLYIGGGTPTALSAPQLEVLLNGLTKNLDLSVLEELTIEANPGDLDAD
                     KIAVLKNSAVNRVSLGVQTFDDKMLKKIGRSHLEKDIYENIDRLKLAGFDNISIDLIY
                     ALPGQTMEQVKENVAKAIGLDIPHMSLYSLILENHTVFMNRMRRGKLPLPKEELEAEM
                     FEYIIAELERAGFEHYEISNFSKPGFESRHNLMYWDNAEYYGIGAGASGYVNGVRYKN
                     HGPIRHYLSAVEEGNACITEDHLSQKEQMEEEMFLGLRKKSGVSMARFEEKFGQSFAG
                     LYGEIVRDLVQQGLMQIEGDHVRMTKRGLFLGDTVAERFILE"
     gene            complement(53487..53876)
                     /locus_tag="VQ540_000227"
     CDS             complement(53487..53876)
                     /locus_tag="VQ540_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HET2544102.1"
                     /translation="MGKLSSILLGTVSGAALALFLTSDKGKQVCSQAQDFLDDLREDP
                     EYAKEQVCEKLTEVKEQATDFVLKTKEQVESGEITVDSILAQAKSYAFQATEASKNQL
                     NNLKEQWQEKAEALDDSEEIVIDITEE"
     gene            complement(53892..54275)
                     /locus_tag="VQ540_000228"
     CDS             complement(53892..54275)
                     /locus_tag="VQ540_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HET2544103.1"
                     /translation="MLEVAYILVALALIVFLVYLIITVQKLGRVIDETEKTIKTLTSD
                     VDVTLHHTNELLAKVNVLADDINVKVATIDPLFSAVADLSLSVSDLNDHARVLSKKAS
                     SAGSKTLKTGASLSALRLASKFFKK"
     gene            complement(54276..55064)
                     /locus_tag="VQ540_000229"
     CDS             complement(54276..55064)
                     /locus_tag="VQ540_000229"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HET2544104.1"
                     /translation="MLDPIAIQLGPLAIRWYALCIVTGLILAVYLTMKEAPRKKIIPD
                     DILDFILVAFPLAILGARLYYVIFRFDYYSQNLGEIFAIWNGGLAIYGGLITGALVLY
                     IFADRKLINTWDFLDIAAPSVMIAQSLGRWGNFFNQEAYGATVDNLDYLPGFIRDQMY
                     IEGSYRQPTFLYESLWNLLGFALILIFRRKWKSLRRGHITAFYLIWYGFGRMVIEGMR
                     TDSLMFFGLRVSQWLSVVLIGLGIMIVIYQNRKKAPYYITEEEN"
     gene            complement(55057..55992)
                     /locus_tag="VQ540_000230"
     CDS             complement(55057..55992)
                     /locus_tag="VQ540_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HET2544105.1"
                     /translation="MSVLVKEVIEKLRLDIVYGEPELLEKEINTADITRPGLEMTGYF
                     DYYTPERIQLLGMKEWSYLISMPSNSRYEVLKKMFLSETPAVIVARGLVVPEEMLKAA
                     RECKIAILTSRAATSRLSGELSSYLDSRLAERTSVHGVLMDIYGMGVLIQGDSGIGKS
                     ETGLELVKRGHRLVADDRVDIFAKDEITLWGEPAEILKHLIEIRGVGIIDVMSLYGAS
                     AVKDSSQVQLAVYLENYDTHKTFDRLGNNAEELEVSGVAIPRIRIPVKTGRNISVVIE
                     AAAMNYRAKEMGFDATRLFDERLTSLIARNEVQNA"
     gene            complement(56122..56298)
                     /locus_tag="VQ540_000231"
     CDS             complement(56122..56298)
                     /locus_tag="VQ540_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000048061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HET2544106.1"
                     /translation="MSKTVVRKNESLDDALRRFKRAVTKAGTLQETRKREFYEKPSVK
                     RKRKSEVARKRKKF"
     gene            complement(56438..57145)
                     /locus_tag="VQ540_000232"
     CDS             complement(56438..57145)
                     /locus_tag="VQ540_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HET2544107.1"
                     /translation="MKVIKVENQVQGGKVAFEILKEKLANGAQTLGLATGSSPLEFYK
                     EIVESDLDFSNLTSVNLDEYVGLDGDNPQSYRYFMQENLFNQKPFKESFLPRGVKDNA
                     EAEVERYNQILADHPVDLQILGIGRNGHIGFNEPGTPFDSQTHLVELDQSTIEANARF
                     FAKIEDVPTQAISMGIKNILDAKSIILFAYGESKAEAIAGTVSGPVTENLPASSLQNH
                     PDVTIIADAEALSLLEK"
     gene            57296..58324
                     /gene="queA"
                     /locus_tag="VQ540_000233"
     CDS             57296..58324
                     /gene="queA"
                     /locus_tag="VQ540_000233"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HET2544108.1"
                     /translation="MNTADFDFHLPEELIAQTPLEKRDASKLLIVNRETGEMQDKHFH
                     SIINMLEPGDALVMNDTRVLPARLYGQKVETGGHVELLLLKNTSGDEWEVLAKPAKRL
                     KVGTRISFGDGRLSAVVTEELTHGGRIVRFEYQGIFLEVLESLGEMPLPPYIHEKLDD
                     RERYQTVYAKESGSAAAPTAGLHFTKELLAEIQAKGVHLVYLTLHVGLGTFRPVSVDN
                     LDEHEMHSEFYQLSEEAAATLRSVKENGGRVIAVGTTSIRTLETIGSKFDGQIQADSG
                     WTNIFIKPGYEWKVVDAFSTNFHLPKSTLVMLVSAFAGRELVLDAYHHAIQEHYRFFS
                     FGDSMFIY"
     gene            complement(58995..59384)
                     /locus_tag="VQ540_000234"
     CDS             complement(58995..59384)
                     /locus_tag="VQ540_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HET2544109.1"
                     /translation="MVKRRIRRGTREPEKVVVPEQSSIPSYPVSVTSNQGTDVAVEPA
                     KAVAPTTDWKQENGMWYFYNTDGSMATGWVQVNGSWYYLNSNGSMKVNQWFQVGGKWY
                     YVNASGELAVNTSIDGYRVNDNGEWVR"
     gene            complement(59438..60145)
                     /locus_tag="VQ540_000235"
     CDS             complement(59438..60145)
                     /locus_tag="VQ540_000235"
                     /inference="COORDINATES: protein motif:HMM:NF019142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HET2544110.1"
                     /translation="MFRRNLNTSFVHAADGIQYVRDDTRDKEEGIEYDDADNGGIIVK
                     VATKPKVVTKKISSTRIRYEKDETKDRSENPVTIDGEDGYVTTTRTYDVNPETGHVTE
                     QVTVDRKQATDTVIKVPAKSKVEEVLVPCATKYEADNDLSAGQEQEITLGKNGKTVTT
                     ITYDVDGKSGQVTESTLSQKEDSQTRVVKKGTKPQVLVQEIPIETEYLDDPTLDKSQE
                     VEEVGEIGKLLLLQSIL"
     gene            complement(60845..61396)
                     /locus_tag="VQ540_000236"
     CDS             complement(60845..61396)
                     /locus_tag="VQ540_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2544111.1"
                     /translation="MKSIGTQILQTERLILRRFVESDAEAMFQNWASSAENLTYVTWD
                     PHPDIEITRNSIRNWVASYTNLNYYKWAICLKENPEQVIGDISIVKIDEADLSCEIGY
                     VLGKAYWGNGMMTETLKAILDFCFTQAGFQKVRARYASLNPASGRVMEKAGMSYLQTI
                     VNGVERKGYLADLIYYGISREEC"
     gene            complement(61794..62618)
                     /gene="nadE"
                     /locus_tag="VQ540_000237"
     CDS             complement(61794..62618)
                     /gene="nadE"
                     /locus_tag="VQ540_000237"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HET2544112.1"
                     /translation="MSLQETIIQELGVKPVIDAQEEIRRSIDFLKRYLKKHPFLKTFV
                     LGISGGQDSTLAGRLAQLAMEELRAETGDDSYKFIAVRLPYGVQADEADAQKALAFIQ
                     PDVSLVVNIKESADAMTAAVEATGSPVSDFNKGNIKARCRMIAQYALAGSHSGAVIGT
                     DHAAENITGFFTKFGDGGADILPLYRLNKRQGKQLLQKLGAEPALYEKIPTADLEEDK
                     PGLADEVALGVTYAEIDDYLEGKTISPEAQATIENWWHKGQHKRHLPITVFDDFWE"
     gene            complement(62615..64075)
                     /locus_tag="VQ540_000238"
     CDS             complement(62615..64075)
                     /locus_tag="VQ540_000238"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HET2544113.1"
                     /translation="MYPDDSLTLHTDLYQINMMQVYFDQGIHNKKAVFEVYFRQQPFK
                     NGYAVFAGLERIVNYLEDLRFSDSDIAYLESLGYHGAFLDYLRNFKLELTVRSAQEGD
                     LVFANEPIVQVEGPLAQCQLVETALLNIVNYQTLVATKAARIRSVIEDEPLMEFGTRR
                     AQEMDAAIWGTRAAVIGGANGTSNVRAGKLFDIPVLGTHAHALVQVYGNDYEAFKAYA
                     ATHKNCVFLVDTYDTLRIGVPAAIQVARELGDQINFMGVRIDSGDIAYISKKVRQQLD
                     EAGFTEAKIYASNDLDENTILNLKMQKAKIDVWGVGTKLITAYDQPALGAVYKIVAIE
                     DETGQMRNTIKLSNNAEKVSTPGKKQVWRITSREKGKSEGDYITYDGVDISDMTEIKM
                     FHPTYTYIKKTVRNFDAVPLLVDIFKEGILVYNLPSLTDIQDYARKEFDKLWDEYKRV
                     LNPQHYPVDLARDVWQDKMDLIDKMRKEALGEGEEE"
     gene            complement(64191..64679)
                     /locus_tag="VQ540_000239"
     CDS             complement(64191..64679)
                     /locus_tag="VQ540_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2544114.1"
                     /translation="MKNRFYYYQLLDEREEQLINKAGSESFYICIALSLLSYIISVLA
                     PSLFNSNMLLIVIIIGTFYFFNRARYLGVTYYSRFHFTILGCFFLTLAITALLMLQNY
                     QFNIEIYQHNPLNFKYLSAWVITYVIYLPWVFIGNLGLKSYGEWAQKKFEQDMDELES
                     GE"
     gene            complement(64669..64878)
                     /locus_tag="VQ540_000240"
     CDS             complement(64669..64878)
                     /locus_tag="VQ540_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET2544115.1"
                     /translation="MAKNLKLKLARVERDLTQGQLAEAVGVTRQTIGLIEAGKYNPSL
                     SLCQSICRCLGKTLDQLFWEEEDEK"
     gene            complement(65268..65710)
                     /locus_tag="VQ540_000241"
                     /pseudo
     CDS             complement(65268..65710)
                     /locus_tag="VQ540_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000640911.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(66002..66808)
                     /locus_tag="VQ540_000242"
     CDS             complement(66002..66808)
                     /locus_tag="VQ540_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2544116.1"
                     /translation="MILKDINFALNKGEIVGLVGRNGVGKSTLMKILVQNNQPTSGNI
                     ISSDNVGYLIEEPKLFLSKTGLENLKYLSNLYGVDYNQERFRSLIQELDLTQSINKKV
                     KTYSLGTKQKLALLLTLVTEPDILILDEPTNGLDIESSQIVLAVLKKLALNENVGILI
                     SSHKLEDIEEICERVLFLENGLLTFQKVGKDSHNFLFEIAFSSATDRDIFITKQEFGD
                     IVQEEGLRITMSGNIQSSELFKFFNENSIKVVDFETKKETLKDIYLNRSK"
     gene            complement(67214..67942)
                     /locus_tag="VQ540_000243"
                     /pseudo
     CDS             complement(67214..67942)
                     /locus_tag="VQ540_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
     gene            complement(68178..68489)
                     /locus_tag="VQ540_000244"
     CDS             complement(68178..68489)
                     /locus_tag="VQ540_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2544117.1"
                     /translation="MIEAQGFLVDKQTRCIHYHSKLDIIALQCYVCKKYYACYRCHDS
                     LENHPFEPYPLSLIQDKPILCGVCLKLLTYKQYKESLSCPFCFSRFNPGCQNHKERYF
                     K"
     gene            complement(68504..69790)
                     /locus_tag="VQ540_000245"
     CDS             complement(68504..69790)
                     /locus_tag="VQ540_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HET2544118.1"
                     /translation="MTKTLKRPEVLSPAGTLEKLKVAVQYGADAVFIGGQAYGLRSRA
                     GNFTFEQMEEGVQFAAKYGAKVYVAANMVMHEGNEAGAGEWFRKLRDIGIAAVIVSDP
                     ALIMIAATEAPGLEIHLSTQASATNYETLEFWKELGLTRVVLAREVSMKELAEIRKRT
                     DVEIEAFVHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYDLYDMPFGKERKSL
                     KGEILEEFSMSAVDMSMIDHIPDMIENGVDSLKIEGRMKSIHYVSTVTNCYKAAVDAY
                     LESSEKFEAIKQNLVDEMWKVAQRELATGFYYGTPSENEQLFGARRKIPEYKFVAEVV
                     SYDDATQTATIRQRNVINEGDQVEFYGPGFRHFETYIEDLHDAKGNKIDRAPNPMELL
                     TIKVPQPVQAGDMVRALKEGLINLYKEDGTSVTVRA"
     gene            70414..70596
                     /locus_tag="VQ540_000246"
     CDS             70414..70596
                     /locus_tag="VQ540_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001262531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ApaLI family restriction endonuclease"
                     /protein_id="HET2544119.1"
                     /translation="MANDNKSHYLIYRVLGISFEEGENIDLYQNKGRFLYKYAGSFLE
                     EAAVLSFNEKFGTENT"
     gene            70606..70971
                     /locus_tag="VQ540_000247"
     CDS             70606..70971
                     /locus_tag="VQ540_000247"
                     /inference="COORDINATES: protein motif:HMM:NF021048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ApaLI family restriction endonuclease"
                     /protein_id="HET2544120.1"
                     /translation="MPNSENTKPKTFEIDCLVGEKHAYEIKWWDATTDGDHITKEHTR
                     IKVIHNKGYIPIRLMFYYPNRTQAIKIQQTLETLYNGIGGKYYYGDSAWEHLRAVTGI
                     DLLSILTDIANKKTGVKSK"
     gene            70968..72158
                     /locus_tag="VQ540_000248"
     CDS             70968..72158
                     /locus_tag="VQ540_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HET2544121.1"
                     /translation="MTVLKGDNLEILKTIESSSIDLIYMDPPFFTQKTQKLSNNKNIM
                     YSFEDTWTSIEDYKEFLSVRLEECKRVLKNSGSIFVHCDKIANHHIRLILDNIFGADM
                     FQSEIIWNYKRWSNSKKGLLNNHQNIYFYSKSKDFKFNTIFTEYSSTTNIDQILVERK
                     RNGNSKTIYKVDNNGNYILAKEKNGVPLSDVWNIPFLNPKAKERVGYPTQKPILLLEQ
                     IIKIATDKNDIVLDPFCGSGTTLVASKILNRNYMGIDLSEEAINITQQRLENVIKTSS
                     NLLNKGIEAYRTKTEEEENILKLLQAKIVQRNKGIDGFLPKHFQKKPIPIKIQKNNEC
                     LNESISLLQNAINSKKLDFGVVIKTHSDNLLFDFDTIPENIIVVDHFELTIEKWLSKS
                     QQLL"
     gene            complement(72673..73665)
                     /locus_tag="VQ540_000249"
     CDS             complement(72673..73665)
                     /locus_tag="VQ540_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000122906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET2544122.1"
                     /translation="MSYYDFVKDYMKVDECKNNEKYSSAGHTFCWKKENSTYAEGLYW
                     FYEGGSFIIDIHDFYIKEEVVQNSTYSMSDYVSIYSSYIVSANGEKFNPYQTITANSL
                     CTFDFDNIKDDFVFLLHENCCYLAVSIGFKKELIEKHLASININPESFYSTLLQPNQI
                     ILTKALERVAMEILNCKMDAPAADFFFKAKANEWISIVIDTYLNRKKYKIEIDDDKAL
                     EDVARFLDDHFATNVNQGTLEKISKMSGTKLKNLFKEKYCQSITEYTQRKRMNVAETL
                     LLNTELPIKEIAESVGYSSASKFSIYYKRYKGKLPSEVRNLACKHHNFKCDYCD"
     gene            73825..75579
                     /locus_tag="VQ540_000250"
     CDS             73825..75579
                     /locus_tag="VQ540_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2544123.1"
                     /translation="MKIYKKLFAYVQDKKYLGVLAIIFSAISAVLTVYGYYLIYKFLD
                     KLIINSNLSGAESIALKSVITLTSGAIFYFVSGMFSHILGFRLETNLRKRGIDGLEKA
                     SFRFFDLNPSGQIRKIIDDNAAQTHQVVAHMIPDSSQAIVTPILVLVLGFIVSIRVGI
                     ILLALTIIGGLILGAMMGEQEFMKIYQESLSKLSAETVEYVRGMQVVKIFKANVESFK
                     SFYKAIKDYSKYAYDYSLSCKRPYVLYQWLFFGLIAILIIPIVYFMTSLASAEVILLE
                     LIMILFLSGVLFVSFMRMMWYSMYISQGNYAVDTLEALYEDMQKDKLVHGNVNNFKNY
                     NIEFENVSFAYNDKAIIENLSFNLEEGKSYALVGSSGSGKSTVAKLISGFYNVNKGSI
                     KIGGIAISEYSDEALIKAISFVFQDSKLFKKSIYDNVALANKDATKDDVMRALKLAGC
                     DLILDKFPERENTIIGSKGVYLSGGEKQRIAIARAILKDSKIIIMDEASASIDPDNEF
                     ELQKAFKNLMKDKTVIMIAHRLSTIKDLDEIIVMDSGKIIERGSDKELMSKDTRYKSL
                     QEMFNSANEWRVSNERVL"
     gene            75563..77284
                     /locus_tag="VQ540_000251"
     CDS             75563..77284
                     /locus_tag="VQ540_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019214631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2544124.1"
                     /translation="MKEFYKKRFALTDGGARNLSKATLASFFVYCINMLPAILLMIFA
                     QEVLENMGKSNGFYIVFSVLTLIAMYILLSIEYDKLYNTTYQESADLRIRTAENLSKL
                     PLSYFSKHDISDISQTIMADIEGIEHAMSHSIPKVGGMVLFFPLISVMMLAGNVKMGL
                     AVIIPSILSFIFIPLSKKYQVNGQNRYYDVLRKNSESFQENIEMQMEIKAYNLSKDIK
                     DDLYKKMEDSERIHLKAEVTTILTLSISSIFSFISLAVVIFVGVNLIINKEINSLYLI
                     GYLLAAMKIKDSLDASKEGLMEIFYLSPKIERLKEIQNQDLQEGDDYSLKKFDIDLKD
                     VEFAYNKDAKVLNGVSFKAKQGEVTALVGASGCGKTTILKLISRLYDYDKGQILIDGK
                     DIKEISTESLFDKVSIVFQDVVLFNQSVMENIRIGKQDASDEEVKRAAKLANCTDFIE
                     KMDKGFDTVIGENGAELSGGERQRLSIARAFLKDAPILILDEITASLDVNNEKKIQES
                     LNNLVKDKTVVIISHRMKSIENADKIVVLQNGRVESEGKHEELLQKSKIYKNLIEKTK
                     MAEEFIY"
     gene            77295..77924
                     /locus_tag="VQ540_000252"
     CDS             77295..77924
                     /locus_tag="VQ540_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000368976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HET2544125.1"
                     /translation="MDNKKLKVKDLVSIGVFGVIYFAFMFGVGMMGLIPILFLIYPTV
                     LAIVAGTVVMLFMAKVQKPWALFIFGMISPLVMFAAGHTYVVVVLSLIVMIIAELIRK
                     IGNYNSFKYNMLSYAIFSTWICSSLMQMLLAKEKYMEWSLMTMGKDYVDVLEKLITYP
                     HMALIALGAFLGGILGAYIGKALLKKHFSNGLYCVGYFTPCLILWCYLN"
     gene            77825..78382
                     /locus_tag="VQ540_000253"
     CDS             77825..78382
                     /locus_tag="VQ540_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001851583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HET2544126.1"
                     /translation="MYRQGSIEKTLFKWIILCGILYSLPNFMVLSELNPIVKMFLSIP
                     IVIRMFILPFMAASFMIKTSDVGAIISSMDKLKISKNVSIPIAVMFRFFPSFKEEKKN
                     IKMAMRVRGINFKNPVKYLEYVSVPLLIISSNISDDIAKAAETKAIENPIAKTRYIRV
                     KIQLIDFVYVLAVAGLIVGGLIWLK"
     gene            78370..79734
                     /locus_tag="VQ540_000254"
     CDS             78370..79734
                     /locus_tag="VQ540_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002837029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2544127.1"
                     /translation="MVEIKNLSLDYGEEHILDDISLSIAEGECVLFTGKSGSGKSSLI
                     NSINGLAVRYDNAKTKGEIIIDGKNIKNLELYQISMLVSTVFQNPKTYFFNVNTTLEL
                     LFYLENIGLAREEMDRRLKDILEIFPIKNLLNRNIFNLSGGEKQILCIAASYIAGTKI
                     IVMDESSSNLDIKSISVLAKMLKILKEKGISIIVAEHRIYYLMDIVDRVFLIDKGKLK
                     KTYTRSEFLKLDKNELNALSLRDKELSKLKVPYLKEGGEYQIKNLSYKFTDDECLSLK
                     DISFKLGKIYGIIGSNGRGKSTLLRCLIGLEKKSKEEIYFKGEKLSKKERLKNSSLVM
                     QDVNHQLFTDEVFNELRLGVKNFDEEKAKIILKDLGLDEFIERHPMSLSGGQKQRLAI
                     ASVMCKTSPFIFFDEPSSGIDYSNMIKISELINKYKTMDKIIFIVSHDIEFLNEVADE
                     IFEL"
BASE COUNT        24632 a        17071 c        14696 g        23717 t
ORIGIN      
        1 acctacggct agcttcctag tttgctcttt gattttcatt gagtattaca gtaaacaatt
       61 tttctagcta ttgtaacaaa aaagtcactc gaaggcaact tttttcgtcc ataaactttc
      121 aaaagagaat ggcttattca gaactaaaag ccgcagcttt ttgcatttgg taatacttac
      181 cctttctatc catgagttct tgatggttac catattcaac aatatcacca tctactaaga
      241 caagaattaa atccgcatcc tgaatggttg acaaacggtg agcaatgatg aagcttgtgc
      301 ggcccttcat gagttttgca aaggcatcct gtaccagcac ttctgtccgt gtatcaatgg
      361 aagaagttgc ctcgtctaag ataagaatct ttggaatagc cagaaagact cgggatatgg
      421 tcaagagctg agcttggccg acagagagag attctccagc attttccaac ttggtatcgt
      481 atccctgtgg caactgttgg atgaaaaagt ctgcattagc tgctttggca gcagcaatta
      541 cttgctctcg actggcttca ggattgccaa aggcaatatt atcatgaatg gtcccttgtg
      601 tgagccaggt ttcttgaagc accataccaa actgctgtct caatgatact cgtgtataat
      661 cataaatgga ttgcccatcc agcaagatat ctcccgagct aatgggataa aaacgcataa
      721 ggagattgat aagagttgat tttccagcac ctgtcggacc aacgatggct accttactac
      781 cagctggaat atcgatagac aactccttaa tcaaaatttt ttcaggatgg tagccaaaag
      841 agacatgttt aaaggaaata gctcccttaa cttggtcact ggtcaagact tccttacctg
      901 tttcagccac ttcagggcta tctaagaccc catagatacg ctctacgcaa gccagagcac
      961 tttgcaactc agctagcact gaagaaatat cgttaaaggg cttggtgtat tgctgaacat
     1021 agttcaaaaa agtcactaaa cgaccgacgg tcaaggttga acccatcatg atacgataag
     1081 ctcctactcc agctaaaagg gcataaatga gtgcatttac aaagcgagtc gaaggattga
     1141 ccgttgaaga ataaaagatg gctgactgag aatagcctga gtagttgtca tgagcctcac
     1201 gcaatctttg gataaattct gtttgagcat tgaaggactg gattatagtc tgctggctaa
     1261 gcgattcttc aatcaactga gtctgaattc ccctcgtctc tgtttgcttc tggaagagat
     1321 gataggatct cttggcaata aagcgtgaaa tcaccatgga cagtggcgtc aacagcaaga
     1381 ctaagagagt catgaggaga tgaatttgga gcatggctag aatactaacc aaaatcatca
     1441 aaacaccaat gaaaaattgg ttaaaaatca tggtcaagcc agctgccaac tgttcgatat
     1501 ccgtggttac acgactgacc atctctccat tgccttgccg atccgcaaaa gcaatcggta
     1561 accgatggag tttatggatg attcgctctc gtaaatctct ggtataagag aagattagac
     1621 gattatagag gagaggattg gcccattgta ccagagtatt tcctattacc accaagagca
     1681 tctggagaaa aatctgccaa aaaactggtg atgaaccagc cactaggact tggtcaatga
     1741 cctgcccaat cagaataggt aggtaaattg ataagccaac ttgggcaata gttcctagaa
     1801 aggctaggaa aaggaggaag ggatggtttg ctaaatctac gactaaacgt ttgagcgtct
     1861 ggtttacagt ttgtcgtttc attctagtcc tcctttccat gttgggatgc attgatttca
     1921 cgatagactt gactggattt catcaagtca tcgtgcttgc caacagctag caactcacct
     1981 ttttccaaga ggagaatctg gtccgccatc tggagtgtcg aagtccgttg agaaatcaag
     2041 attaagctca tatttggcag attttcgcgg atagctttca agagcttgga ctctgtaatg
     2101 gtgtccagtg ctgaggtcgc atcatctagg atgagaaacg gagcctggcg caagactgct
     2161 cgtgcgatag acagcctttg tttttgtcca cctgagaaat ttcgccctcc tgcttcaact
     2221 agagcatcca agagtccttc cttatcactg acaaaatcct tagcttgcgc aatctccaag
     2281 gcttgccaga gttcttgatc agtcacttct tgatttaaac ctaaagtcaa gttggaacga
     2341 atagttccct taaagagttc gaccttttga ggtacatagg caatccaaga ccgccactgc
     2401 tccaaattaa gaggactacg tccattttga taaaggtcaa tgttcccctt gtctactgga
     2461 taaagtccaa gtaagagttg caccaagctt gatttaccag aaccagtccc cccaatgata
     2521 ccaaggattt gtccttgagt catatcaaag gaaatgtctc tcagagaagg ctgggccgca
     2581 tcaggatagg taaaagtcaa ttcttggact tgtaaaaccc gaccactggt aacttgcttt
     2641 tgttctaatt ctgaatggat gttttcggga gattccgcaa agacctcctc gattctcttg
     2701 gctgagatat aggactggtt gagggaattg atcagcatgg ctagcttgac caattccacc
     2761 aaaatctgta agaggtaatt gataagagca atgagagcac cttgactgag tactcctcct
     2821 tgaattgaaa tatagccttg ccagataata acgagaagag ttccattgac aatcagatag
     2881 gtcagaggtg ttaataaact agacaagaaa cctgtctttt cttgtaatct agcataaact
     2941 tggttaaggg tttgaaaaat ctgtaactct cgtttttctt gaccaaaagc acgaataacc
     3001 cgcatccctt gcaattgctg gcgcgtttcc tgaaccagtt ggtccgtttt ctttctgaga
     3061 ctactgtaga gaggattgac caatcgagat aaccctacaa tgacaatggt caaaatggca
     3121 accatgacta agaaccagaa agtcaactca gctgagattc gataagccat aaaaatggca
     3181 ccaaaaacga taatgggcgc tcgtaaaaag agacgcagga attgattgat accagtctga
     3241 atctggtagg tatccgaagt caagcgagta accaaactag aagttgtcag acggtctctg
     3301 ctgtcctttg gcaaggaaag aatatgacga taaagatcgt ttgtcaattc cttagcaaaa
     3361 cctactgctg cctttgctga gtaaaattga gctatcaagg ccactaaaac gccaattact
     3421 gcaaagataa ggagcaggcc aatctgcatc cagagatgac cttgatctcc ctgaggtaaa
     3481 gattggtcaa caatcccagc aatcaccatg ggaaccaaga gctcaaaaac agcttctaac
     3541 agcttgaaca agggggctaa aattgattcc ttgatgtagg gtttgaagta agataatagg
     3601 tgtttcataa atcccttcta ttcatattct agaaatgaag aaagtgggaa gccccactct
     3661 ctgttttatt tgtttaagta aggcaataga tagccatatc ctgctttttc catctcatcc
     3721 ttggccacaa agcgtaaaga agcagaattg atacagtaac ggaggccgcc taactcccgc
     3781 ggtccatctg tgaaaacatg acccaagtga gcactgcctg aacgagaacg aacttcaatt
     3841 cgctccattc catggctcag atccttgtaa taatgaatca actctttgga aatcggacgg
     3901 ctaaaacttg gccaaccaca acctgaagca aacttatcct tggcaaaaaa gagtggctca
     3961 cctgtcgtaa tatctacata aatcccctct tcaaaggttt ggtcataggc attggtaaat
     4021 ggagcctctg tagcagcttc ttgtgtgaca cgataagact cttcagatag actggccttc
     4081 aacacctctt gactaggctt ttcatagttt gctgcatcaa tcaatggctt atcagcatcg
     4141 gtcacatcga tatgacagta acctgaagga ttcttcctga gatagtcttg gtggtagtct
     4201 tcagccagaa tgtagtggcg taattgctcc acttctactg caatctttcg acccagcatg
     4261 cgttcctgct cctgcaccac tgtgtagata gctggcaaat ctgcttcatc ctgataataa
     4321 atcccagttc gatattggcg accacggtca ttcccttgtt gattgataga tagaggatcg
     4381 ataactcgga aataataaag taaaatctct ctgagtgaca cttccttctc atcgtaaatc
     4441 acttggaccg tttctgcatg gtctgtttcc ttgatcaact ggtaattggt cgtttcgact
     4501 tgaccattag cgtagccaac actggtttct agcactccag aaatgcgtga aaaatattcc
     4561 tctaggcccc aaaaacaacc acctgctaga taaatttctg ccatctttat ttctccttta
     4621 tcacgttttt aactaatact cttcgaaaat ctcttcaaac cacgtcagcg tcaccttacc
     4681 gtaggtatgt tactgacttc gtcagttcta tctgcaacct caaaacagtg tcttgagctg
     4741 acttcgtcag ttctatctgc aacctcaaaa cagtgttttg agcagcctgc ggctagcttc
     4801 ctagtttgct ctttgatttt cattgagtat aaacttcttt tcacaaaaag gatatgaaac
     4861 cctctggtca agagtttccc catcctatct tctattcttt attttgcttc tacacggaca
     4921 cctttggtat caactctcaa gtcatgcagt tttcctttga aaggttgctt ttccaattct
     4981 gccttaattg ttggcatctt gtcatgagaa gccagaacca taactgtcgg cccagcacca
     5041 gaaaggtagg ttgcataggc cccattttct ttggtcactt gcttaatcat cgcaaattct
     5101 cttaccaagt cctgacgata gcgctcatgg aagaggtctc cctcgattgc ttgcccagcg
     5161 gtcaccatgt ctcctgccaa caaggcagca accgctacat tggcgataga acttgcagca
     5221 acagcttcct tataagacaa ttttttaggc aagacactac ggctgtcgcg agtacgtaat
     5281 tcatagtttg gaatgtaagc tagaaaatca cactctggaa agtctgctac gatagcagag
     5341 acttgccctt caacagaact tgcaataacg agattaccat aaatggctgg agccacattg
     5401 tcaggatgcc cttcaatctt ggtcgctaac tgcaattttt catggtctga taagttgagt
     5461 tgacccagtt ggttggctag ttcaatccca gcaacgataa ccgagctgga agaacccaaa
     5521 ccgcgcgcca aagggacatc actggtcatt ttcaagcgtc ttggttgcaa gtctggtaca
     5581 atttgcaaag cgattttaag caagagatta cgctcgtcat gtggaatcca tttgccaatc
     5641 tggtgttcaa tcagccactc atctcgttct tcgcagacct caatttgaag atacttggtt
     5701 acagctacac cgaccgagtc aaaacctggc ccgatattgg cactggttgc aggtacaata
     5761 atcttcatct tattctccta gcaccttgaa ggtattcaag aggtcgaatt ctgaaacctt
     5821 cttcaattca gctgagacat tttcaagctg ggctttatta atcttgtgtg tgatgataac
     5881 gacacgcgcc ttgtcaccct ctttgccatc ttgaaggatt tgcttaaagg aaatatcttg
     5941 agcattgaag atttcagcca acttcaagac ctgacctttt gagtctagag ccaagattga
     6001 gaaatagtag tttgctttga catcttcagg atttgccaag accaagtcac ggctatattc
     6061 gttgaagtct ttgccaatag taccatcatt caaacgacga acgatacgga caatatcagc
     6121 tacaacactt gttgcagttg gtttttgacc cgcacctggt ccgtagtaca tagactcacc
     6181 aataccgata gattctacaa agacagcgtt cattacgcca ttcacactag caagtgggtg
     6241 cgctttaggt aggaaggttg gagtcacttc tgcagcaata cctgaagaag tttcctcaat
     6301 agaaccaacc aatttcacta cgtaaccaag ctcttgagct acagctacgt cttctggtgt
     6361 gatattgcgg attcccttgt gggctacatc atcaaaggca atcttcatgc caaaggcaaa
     6421 ttggctcaaa ataaccatct tgtaggctgc atcaatccca tctacgtcat tcgtcggatc
     6481 gctttctgca aatcctagac gttgtgcttc cgcaagagca tcatcgtaag accagccttc
     6541 ttccaccatc ttggtcacca tgaagttgga agttccgttg actactccaa gcacgcgcgt
     6601 aattttatca gaagccaagg aatttgctaa agtacgaaga attggaatcc caccagcaac
     6661 tgctgcttcg tagtaaagtg ctaccttgtt agcttgagcg atttctagca attctgcgcc
     6721 atggacagct aaaaggtcct tgttagcagt aacaacgtgt tttccagctt ccaaggcacg
     6781 agtgataaag gttttagcag gctcaatacg ccccatcaat tccactacga tagtaatatc
     6841 ctggtctgat aaaatatcat ccacattggt tacaaagtta aagtcattcc ctgctgcaag
     6901 caagcgattt ttttcatctt catccttgac caatacctta gcaactttga tatctgaatg
     6961 tgctgattga ttgatttttc ctccattttc ctttaggagg aaaggcacac cacttgcaac
     7021 ggtaccaaat cctagtaaag caattttaac tgtcatcttt atctcctcga aattttctaa
     7081 tatagccatt ataacagaat tttgtgaaaa ttcctattat agtaaatcac tatttcagta
     7141 taaaaagaaa aaacgaatca gacgattcgc tcttcttaaa atctgaaaat agctttccag
     7201 aaaagattag ccgatttttt gcagattgag cactgcatcg tgactcatca agacttgacc
     7261 atactcttgt aagactgagc gactgatatc actatcgtct gcaaactcgc gcatacgggc
     7321 caacagccaa gctggatatg ggcttggatg attttcaata tccactaaaa tggtcaaata
     7381 atagcgctcg ttcattttgt agagttcaga agtttccatt tcaaaagtca ctgtcttggc
     7441 aaaagctacc aagtcagcca acttagcaaa agaaaggatg tagtagatgt aaggttcttt
     7501 cttactctca gcttcttgtt cagcctgctc ttgctcttct tccttggctt caacttgctc
     7561 aagagattga atggcttcga tatcatcctt ggttttgtct gcgatgcttt tttccagggt
     7621 tttgataaat tcatctggag acatttgagc caattcttcc atatctggca aatccgataa
     7681 gtcttcaaaa tctagatttt ggtcaatctt tgacttggtc acaaagacat ctaccttatc
     7741 aggttttgga gtcacacgga agctcaacat gcctgtatcc agaaagctat caggcatctc
     7801 tagctcatcc aagatagcat aaaagaactc ttctgttttt tcttgaggaa cgagaaagtc
     7861 agcaatctcc attccacgat ccatcaaatc ctctaaagac atcgtgattt ttaaagttgt
     7921 atcactaatt tgtttcattt tcattgctag taacctcata ctttcagttc tatctattat
     7981 actagatttt tacgatttta tcaaaagaag gctcctctat acggatagat tttccctagg
     8041 gtctttctat aggagactcc aagagaaaat ttctgcagac agatagaaaa agccttcaaa
     8101 atcggctaag agccgatttt gaagacctta tacatcagaa tacttataat ttaaaggttg
     8161 ctacaccgag gatagaacga tttaagtttc tgagaatttg aagactttgc tcaaatttct
     8221 tataacgagt cactccgtac tcttcaacaa gaaggactgt atctctttcc aaaagagatg
     8281 atacatcctg taaatctaca aaatgcattc cttttaaagc ttcttgactc tgtttcaatt
     8341 tatctaggat agctttattt gagctaacga tggtcaattc ctgtccagta tttttgtatg
     8401 acaaaacatc tgctaggtta gcaattgttg taatctctgt tacaaaatca atttgatact
     8461 gagaaaaatc acctactcta ttgattgttg gattaaagag ataaactaac acatttccca
     8521 tcacaaccaa aatcacacaa accactccaa taacaactaa acgaagaatc agatttttca
     8581 catttaagcc aagcgctgtt tcaccatttg cgttcaattc tttagagttg atggtttcca
     8641 gtttttcaat tttcacattt gcataggcat gtttaaattt ctcaatcaac ccatcaattt
     8701 ttttctctaa caagtcattg gcatctttac ttgatgtcaa aattttcaca ccaacccctg
     8761 catcgtcaat catatagtag acggtcaatt ttttccacca atagtcattc gttgaatttt
     8821 tcaaggttgt ttctgtcgtg tctaattcac tggcaatttt tttcaactca ctgggttcta
     8881 catcattgaa aagataagct ccattcaaat taccatcaat caatttccca taaaaatcac
     8941 tataaccacc aatttgatga ttcaaaatcg ttttggccga ctcttttgga ggagtgattt
     9001 tatagataag ataagttgaa taacttgttg tatctttgac agtgttttta ttcctaactg
     9061 ctttaattgt aaatggtaca gcaatgagag caaataaagc gatgagagct aaaatatttg
     9121 cttttcgctt tttataaaga tttgcaaaca aatcagctac tgaataatgt tcaaacatga
     9181 tttttttctc ctttgtttag tagatactag ttttcctttg taagcatttt tgctataaat
     9241 ataatcacaa gaacaattcc ccagaattgc attgtaaata aattgaagaa actttctgaa
     9301 aagctgcttc ttggcataaa gaatagatta ttcaagatga gtagggataa agcaaatagg
     9361 attgtccttg agcgataggc tacttgcagc atggctataa ataatacgcc gagtaagaaa
     9421 ctaagcagaa agactccaat cataccatag tcggtataca actccatgat ataactactt
     9481 ccgataccat gccctttcag gtattccttg ttcaagacaa gataggatag attgtgggca
     9541 taactattac tatcaatagc tagttccaca ctattggttg tatgttcaaa ggcttttcct
     9601 ccgaaaatgg ctcccaaact cccccttgca aaataatcaa gaacaggacc aaaagtaaaa
     9661 ttacggaaat ctcggtaagg gaggctactg ttaaatagaa aacctcgagc cagaacacca
     9721 aaactagtcc cttgtttata gataaagtca agtaagatat cccagaaacc tgtatgggaa
     9781 acttggacat tatcccgtac ataattgagt actcccatcg ctaacatgag aataggagaa
     9841 cctacaaaaa tcgctaactt ttctttaaac ccaatccatt ttcctttttc agtttgctcc
     9901 cgcataaagt aataaacaaa agcaaataaa atacttaaaa taaagggatt tcgtgtccca
     9961 attgccaaat gaatagtatt agctgcaata aaggagacaa gcactgctgt ggcctgcaat
    10021 ttctttggct tggttgccag atacatacac attgcataga ccgtaaaggt agacaaaatg
    10081 taggtaaaat aaggcagttt actttcaaaa tttgcatagt aggcatagta ggaagtctgc
    10141 aaacgataca agagccgttc aaataaccga atgaaataga aaggataagt tagaagaaaa
    10201 actcctagtg atacaaagcg taaccgcttg atataaacct cttttagaga atttcctata
    10261 tttgctactt ttattttctt cctagctatg aagtaacgag ccagaatgcc tcctgtggtc
    10321 aagcccagaa tcgaaaccat gacaactata aaggcaaaac gataggctat tggatgatag
    10381 gtatccaaag caccatccct aaaataatca atggtcggtc ttgataccag aaatacaaaa
    10441 atggttaaat agaaaataaa atggattaag taatacttga tatcattcca acaagcaatt
    10501 aagctactaa ccaacaagaa caataaagta gaaagtaagc taacattatt attattaaac
    10561 agatacacaa ttccacttac tagcgtcaag gcataactga ctatggtcaa actaaataat
    10621 aatcgtttcc catcaatcac ttggtcaccc ccgttctaat gtaatttttt agatttttca
    10681 atatttttca gtaataagaa tcgatataag gaaatattta tgaatagggc caaagcacta
    10741 attcttctcc ccttacggaa aattggattc ctagaaatag caaaggcatg gccttttaaa
    10801 aaacgatgaa tctgagaata ggcttcaaac tgtttatact gatcatctag caacatctta
    10861 tccagaataa agaagtgggc ataggccaat ctgaaaaaag cgacctcttt caagtcagga
    10921 tagtttttca caacttcatt ataaaacttt tggtagatat caatataggc taaatccttc
    10981 tctgcatagg gtttggtcgt aatactatcc cctctatgga aatagtaata atagggttta
    11041 gtattaacca catacttctt ggccaacttg attaaatcaa aatggtaata ggcatcttcg
    11101 taaatcaacc ccttaggaaa ggatagggca gttgcaatct gtctcttgat tagcttattg
    11161 caaatcgtcc caggtatttt ttcacctatg aggtattcct ttagaaatgt ttgagaatca
    11221 cagacaaaat agtcatcctg attggctgac tgtgggcttt catcattagc atagacattc
    11281 atgacaccac agcttgaaac atccgcatct tcttgaacta attgctcata taagctctga
    11341 atcatttctg gatggatata atcatctgag tcaataaaaa tcagataatc cccgtgagcc
    11401 tgcttcatcc catcatttcg tgcttgcgac aatccttcgt tctttttatg aagcactgac
    11461 accctgtcat cttgttcagc gattgagtca cacaagcgac cactttcatc tgttgcacca
    11521 tcatcaacaa gaataatttc cagattttga tagatctgct tctgaatgga agctatcgat
    11581 ttttctaggt actgcgccac attatagact ggcacaatca cactaattaa tgcagtttcc
    11641 atgctactcc tctaatagtt tttctacttg ttcgatttgt tttgtaattg taaattgttg
    11701 aatgaattgg ctagcctcat cgacatcaaa gtttgaggca gaagtcatgt aattagtaat
    11761 cgcctgagct gcctcttgat tgctctcaat gatttgtcca aatcgtcctt cttgggataa
    11821 ttcctcagcc cctccaacgt ccgtagagat aaaagggagt cccagactca aggcctccac
    11881 atacactcca ggaaaacctt cttgtttaga catagacaag agaactttcg tctgagataa
    11941 atactgataa ggattttttt gataaccaag gaaatgtaca tagtcctcaa tcccatactc
    12001 tttgactcgt tttttcagtt cctcttccat atcaccagcc ccgataaaat agagatgata
    12061 gttttttccc tcttggtgta ataatcgtat cacttccact acacggtcag aacccttatt
    12121 ttcctcaatc cgtccgatag tacagatact ttgaggagca atctcgatat cgatcttctc
    12181 ttgagatttt tctagaatag tctgaaaatc atatccattg tagattatct gtaatttaga
    12241 agcataatct ggataaactt ccttgataga attgctggtc ttttttgaaa tccctacaat
    12301 tgtattcgca gcatccaact ggcttctatg tgattctctt ttagagctat ccttaagaag
    12361 ttcttcaata cttccatgaa tccaagatat cttcttgact tctcttcttt tagagaacaa
    12421 cagtggtgga ttcataatgg taaaagaaac ttcaacatca taatcatctt ttacaagcaa
    12481 acgacgagtc agtcttggaa aataaattct cattctccac aaaaaagctc gtaaccatct
    12541 ggtttggcga taatcttgaa gggattttaa aatgcgtaca tgctttggaa cagattcata
    12601 tcccttgtca aagtgctcca tttcaagaat atcaatatca tacttttcta gatccagatt
    12661 tgaaacaatg gttgatagaa tcttctctgc accacctcca agagaaaaag accacataaa
    12721 aaataagatt tttttcttag ccaccatatt ctcccttgta ttctgtataa gacttatcca
    12781 tatcagcgat gacagcatca tgatgcggta cctgcttgtc tgctggtgga ggcgtcatat
    12841 aatccccaaa agcagttctg agatagacat catagccgat tggaataggc atctctgttc
    12901 cttcaaatgg caagaaaaga ttgtcttcaa aagatgtgat tgggtacttg tttctcatgt
    12961 agccaggacc tgagcataat tctgtaatgc catcacaatc agccaaatca tacttagtca
    13021 tttctttctc agcttttttc cagatgcgat aacggagaga ttttggagtc aaacccagta
    13081 aaatgcgact tccccatttc atgagagcac catgcttttc tggaatagtt tgcgcacaaa
    13141 agagtgaata aatcaaggcc caacgaacct gttttttccg ctcagctgga tttttcggat
    13201 aataatccaa aggcaaaaca tccaaggtca gaccatgtgg caaatctaaa tcctgctgat
    13261 aaggcttgat acaggtggtt tccttgtcac gaatggtaat aaaaagatta cgatcaacaa
    13321 aatccttgtg actctttgac aagaaataac gttcatctgc ataacgaggc cataattctg
    13381 ctaatttctc ataatcttta cgaggcataa aaaagtctag gtcgtcgtcc caaggaataa
    13441 atcccttgtt tcgaagggca ccaatagcgc ctccgccaca gagataacag agcaaatcat
    13501 gttctttaca aaaggccaca aaatattcag ccatctccag actacgagcc tgaattgctt
    13561 ttaaatcagt catattgttc attattcttt ctatcgtatc gtttcattat accacaaaca
    13621 aggggtgaaa atctattgca gactgtaaaa aatcaaagcc tgactgctat ccaaatagct
    13681 atcaaacttt gatttttctg tcttatactc ttcgaaaatc tcttcaaacc acgtcagctt
    13741 caccttgccg taggtatagg taactgactt cgtcagtctt atctacaacc tcaaaactgt
    13801 gtttttagca gcctgcggct agcttcctag tttgcacttt aattttcatt gagtattatc
    13861 ttatctcaag cccatttgag cgagcttggt ttgatatttg ttttgatcaa ccagcaagcc
    13921 caagcctcca taaacatcat aggcatctac ccagtcaccc agttctggaa tcgtcaattt
    13981 ttcaatacca ttttttgctc catccaaaac agataaaccg tttgttagga ggaaagtata
    14041 gggtacgttg gttgaggtca tagcaaaaac ctttccaaga gcttcagaac cagtgaaaag
    14101 tttagtggga tctttaattt gctctaaaat tgctgttaaa acttgttgct gtctttttgt
    14161 acggccgtaa tccgcctcat catcatcacg gaaacgagca taattgagca gggtcgagcc
    14221 attcatctgc tgttttccga ctttaatggt ttgggttgga gactcagtct cggtagcgta
    14281 taaatcatct ccgactgtag cttctgttag gggacgccca ttcaatgttg aaaattgagc
    14341 atcaatcgtc accccatcag ggaaaagcgt gtcaatcgct gtggcaaagg cctggaaatc
    14401 aaccaaggcg tagtacttaa tgtccaagtc aaaattatct ttcaagactt ggcgaaccat
    14461 ttctgcccct ttttgcccct cttgttctcc taactcgtag gctacgttta acttgttatc
    14521 tgtctgtttt ctaccattaa tcacttgact ataaccatct atatagacca aattatcacg
    14581 catgaaactg actagcttca ttttcttatc tgagcccccg acatttaata ccataataga
    14641 gtcagttcgt gtctcaacac tgttctggcc gattcgacca tcagtaccca tgattaaaat
    14701 attaactcca tctctagtgt cctgaccatt aaagacttct acttgagctg cccgggcatc
    14761 agcagttttc tttgcgctag catcttggta accacgcaaa aacatgaata ccatggccaa
    14821 agccacacag accaaaagtg aaaaaatcac cataaaaatt cgtttaagac ggagcttccg
    14881 tcttttcttt tttggaggga aagagagtgc ttgtgatttg gattgtgagc gactccggtt
    14941 cgcatagctt ggtaagtcaa cctgctcttc tctttcttgt tccaagctag agctactatt
    15001 tcccctagca agagttagct tttcttgcaa ataggcaaac tcattttttt ctctctcatt
    15061 gagatagtga atatttttta gcaaataatc ataacgcaac tgctcatgat gacttaaggg
    15121 attttcttta ctcatcttct ctcctttcca tggtctgata ttggataaat aggataggca
    15181 cccagaattt tatactggat tccaatcgct tctaattctt tttgggcaaa gtggaccaag
    15241 tccttatcga tataatccac atcgataatg aaaaagtatt cacccagtgc tgtcttgagt
    15301 ggacgacttt caatttttgt caagtcaatt cctcgccaag caaaggtcga cagggcctta
    15361 taaagtgcac ctggaaggtt gtcaggtaat gtcaaggcca aactcatctt ttcagtttgt
    15421 gcttgcaagg gaatactagg cttttcagct cctagaaccc agaaacgtgt gaaattggct
    15481 tccatttcct gaatatcctc ggcaatcagt tccaatccat attcttcagc agaacttcta
    15541 ggtgcaactg ctgcaaaggg ctggtctgga tgttcggaaa taaaacgggc cgcataagct
    15601 gtactagctg ttacctcgat ttgagcctct ggatattgtt catcgatgaa tttctttcct
    15661 tgagccaagg cctgtggatg tgaaaaaatc ttttcaatct tagtatggcc tggaaccacc
    15721 atcaactgct gatgaatagg ctgaacgatt tctgctactg cttggatgtg agcctgatga
    15781 aaaagatagt ccaaggtttc atgaacacta ccctcaatag aattttcaac tggcaccaca
    15841 gaatagtcca ctaatccttg ctcataagcc ttgatgacat ctgtaatgtt ggcaaaagcc
    15901 tgcaattcct catgaggaaa agctgtctgc acaacgtggt gtgaaaatga tcccttggga
    15961 cctagataag ctattttcat cttagttcct ctataatttc ctctgggctt agcttggtca
    16021 catccaaaac ccgactagcc acttcctcat accaagcctg tctttcttga aaaatagcta
    16081 ctagttcttc cttgctatta tttagaaaaa gcggtcgctg attgtcctta tcagctgcga
    16141 tacgtaggta gagggtttca aaatctgctt tcaggtagat gttatctgta ttagtcttga
    16201 gtaagtcacg atttctctga gaaataacca ctcctcctcc agttgacacg acttggtctg
    16261 tttgtagtaa atcagctagg acttctgatt ctacatgacg aaaggctgct tctccctttt
    16321 cagcgaaaaa attcgcaatg gacataccta ggcgcttctc aatcagagca tccatatcaa
    16381 ggtaattagg gtccaagcct cttgcaatag tcgattttcc agcccccata aaccctaata
    16441 acaccttagc catgaatcaa gctctccaaa tcatcaaaga aactaggata gctggtattg
    16501 atggcttctg cacggtcaag ctccacctct ccatctgcaa ccaagagggc tgcgatagct
    16561 gtcatcatgc cgatacggtg gtcaccaaac gtattgactc tagcaccgtg aagagctgat
    16621 ttccctttga taatcatccc atctgccgta ggagtaatat ctgctcccat actatttaag
    16681 gcgtctgcca caacctgaat acggtctgtt tccttgacct tgagctcctc agcatccttg
    16741 ataactgtta caccttgggc ttgagtcgca agcagggcaa taatgggcaa ttcatcaatc
    16801 aatcgtggaa tcaaagcgcc accaatctct gttcctttca agtcagaaga ctcaacaatc
    16861 aaggtagcag atttagcgac tggatcgatt tcagttattt ccaattttcc acccatggca
    16921 cgaatgacat caataatacc ggtgcgagtt tcgttgatcc ccacattctg cagcactaga
    16981 cgagaatttg gagcaatcaa acctgcgact aaccaaaagg ctgcactgga aatatctcct
    17041 ggtacgacca ccttctgtcc tgtcaatttt tgtggcccct ggactgtgat tttcttacca
    17101 tccacactta aatgaccacc aaattgttgc aacatatctt cagtatgatt acgggtgtac
    17161 tctttttcga taataactga ctccccctta gcttgtaagg ctgcaaacat caaggctgac
    17221 ttgacttggg cagaggcaat tggcaactca taatgaatag gtcttaggtt tttcgtccct
    17281 tttaagcgaa ggggaggcaa gtctcgttca gtttgccctg aaatgctgac gcccattttt
    17341 ttcagtggaa gggtcacacg gtccatagga cgtttggaaa gactatcatc tccaaacatc
    17401 tctacttcga aatctgcacc agcaaggaca cctgaaatca ggcgaatcga ggtgccagaa
    17461 tttcccatat taagggcatt ttgtggcgct tttaagccag ccatgcctac accttgaatg
    17521 gtaataaccc catctttatc ctcaatttca acaccaaggt cacgaaaaac ctgcatggtc
    17581 gaaagaacgt cttcacctcg cagaatatca taaaccttgg tctcaccctc agccaaactt
    17641 ccaaagataa tggaacggtg gctgatagac ttgtcacctg ggacgcggat actaccatgt
    17701 aaatggcgaa tgtttgtttt tagtttcata ctggacctca tacttgcaat acttttacct
    17761 attttatcat aaaaagtcag aaattcctta aaaattcctg actttaggat cgttcttttc
    17821 ttatttcagc aattctgaaa ctggttcaaa aacaattttt tcaatgtcag aaaggtaaat
    17881 ggccaattgt tgttgcttgg taaagaattc tgacaagagg ctatttcctt gaatctgttt
    17941 accaaagcct tccatcttag cttggaagga cgcatctggc atttgacctg tctgtgctag
    18001 tttttgaatt tcctcttgaa aggcaagata ttctgtaaag attttgcttg cctcagcatc
    18061 tgctgcaatc gcatctttag ctgctttaac agccttgtat tctggtaatc cgcgtagacc
    18121 gcgactgagt tcgtttgcac tatcgtaaat atttgacatg ttcttctcct tatttgatga
    18181 cgactgtata gtcggtattt tctgttatga gatgctcagc tctttccaag tcttgagcat
    18241 ttttaaatga aatttgtagg attccgtgaa tatcctcacg attttcctcg ttgatgtgga
    18301 tgttaaccaa ggaagttcca cgtagcagtt ccaaaatccg caggatgaca tcttcttcat
    18361 caggaacgtc aacatagagg tcgtaagagc tatccacacc accacgctta tggatttcca
    18421 tggtctggcg ttgttcacgc gcttggttaa aaaagttcca aatttgctct tcatctccct
    18481 tactaatggc ctgaccaatc acttccaaac gttccttgaa atcctcaatt ctatccagaa
    18541 tggtctcgct attggacaag agaatggagg tccacattcc tggctcgctt tccgcaattc
    18601 gggtcatatc tcgaaaacca cctgccgcaa agcgccttgc catctcatgc tcttgagcat
    18661 agaccgcagt ctgctccatg agactagaag ccaaaatatg aggaaaatgg ctaatctgag
    18721 aagtgacacg atcatgctcc ttggcatcaa tctcgataaa acgagcatga agacctgaaa
    18781 gcagatcctt catttcctta agcgtgtcct gacttgtcag gcttgaaggt gtaaagatat
    18841 aataggcatt ttcaaaaaga ttgacatctg ccgaagcagc ccctgtcttg tgactaccag
    18901 ccatgggatg ggccccgaca aagcgaacag acttgccagc caaatactgc tccgccgcat
    18961 ccacaatggt tgacttggtc gaaccagcat ctgaaataat aacgccttct cgcaaatcca
    19021 aattggccaa ctccttaatg aaagcaatag tttgtttgat tggcaagctg aggataatga
    19081 catctgccaa aggagcaaaa ctagcaaaat catccgttgc acggtcaatc ataccttctt
    19141 tcaaggcgat atctctcgaa gcttgactac gattataacc taaaatttca taatctggat
    19201 gatcgcgttt gataccaagt gccatagagg ctccaatcaa cccaagacct gcgatataga
    19261 ttgtttttgc cataggaact ccttaatagt tctttgtata gtctcggtgt ttggctaccg
    19321 cttcttttag ttcctcaaga ttatctgatg agaatttttc gaggatttct tgcgccagaa
    19381 ccgttgctac aactgcttcc atgaccattc ctgcagctgg aagagcagtc ggatcacttc
    19441 tctccacggt tgccttgtaa ggttcgtggg tttcgatatc cacactcata agaggtttat
    19501 aaagagtagg aatgggtttc atgaccccac gaacaacgat gggttgccca ttagtcatac
    19561 caccttcaaa accacctaga ttattggtac ggcgagtata accgtcttct ttagaccaga
    19621 gaatttcatc cataacttgg ctgcctttac gataaccagc ctcaaagcca agaccaaatt
    19681 ccaccccttt aaaggcattg atagagacaa cagcttgagc caatcttgca tccaattttc
    19741 tatcccattg gacataggaa ccaagaccaa ctggaacgcc tccgacgact gtctccacaa
    19801 ccccaccgat ggtatcacca tcacgtttga tttggtcaat atagtccttg atttcctgtt
    19861 ctcgttcttg gttgacaata gaaacttcag actgggcagc tctttgctta atttcagcga
    19921 ctgtcagatt ttcaggaaca tctatttcct taccaccaaa gaccacgaca tggttggcaa
    19981 tctccatatc cagctcagcc aagaggcgtt tggctactgc accaactgcc acccgcatgg
    20041 tggtttcacg agctgatgaa cgctccaaag aatttcgcaa atcatcaaaa cggtacttaa
    20101 tccccccaac caaatcggca tgacctgggc gaggatgagt aattttccgc ttgcttttaa
    20161 ggcggtcttc aatgtcctcc gcagacatga tgtccagcca tttctggtgg tccttattga
    20221 tgacatccat agtaataggc gcccctgtcg tcttcccgtg gcgaacaccc gaagtaaaga
    20281 caacctggtc actctcaatc ttcatacgac caccacgacc gtagccaccc tgacggcgtc
    20341 taagatcctc attgatatcc tcagctgtca atggaagtcc agctggaatt ccctcaataa
    20401 tagctgttag acgggggccg tgtgattctc ctgcagttaa atatctcata cactctcctt
    20461 attttaccaa gtagtctttc atctcttcca gagaaactgg gtgaatggtc gctgaaccaa
    20521 gctctggcac caagaccaat ttcaaggtgt taccacgcgc tttcttgtca tgagtaagag
    20581 cctgataaag cttgtcaact ttccaatttt catagtcaac aggcaagccg aatttctgac
    20641 acatctctgt gatagattgg gtaatgccag ctggcatgag gcctttttcc tcagcaacct
    20701 tggaaatctg taccattccc atggcaacag cctctccatg catgaccttg ccataaccgg
    20761 cagtcgcttc gatggcatgg ccaatagtgt ggccaaaatt gaggtaaaga cgaataccat
    20821 tgtccaactc atcttcaacc accatcttgc gcttcacctg acaagaatgt tcaatcaagg
    20881 tctctgcatg ttccaaaata ctctcaacag aaccattcag tcccgtcaag agagcccaca
    20941 gttctggatc ctcaatcaag ccatacttga taacttcacc catcccttca atcaactctc
    21001 tttttccgag ggtttcaaga acaagtggat caatcagaac cccatctggt tgggcaaagg
    21061 tccccaccat atttttagca aatggtgtgt taacgcctgt ctttccaccg atagaagaat
    21121 caacctgagc tgtcaaacta gtcggaatct gaacaaagtg aataccccgc atataggtag
    21181 aggctacaaa gccagccagg tccccaacaa cgccaccacc aagagcaacg attccatcgc
    21241 tacgagtcag accttgcttg actagaaatt catagacttt ctgaacagta gttaaattct
    21301 ttctttcttc accttctaag aaatcaaaaa cagctacctg aaaaccagca tcttctaggc
    21361 tgagcttgac cttctctgca tagagagagg ctacatggtt atctgtcaca atgactacct
    21421 tttgcggttg ccagagttct cgcaaccact gaccagcctg ggccatacaa cctttttcaa
    21481 tctgaatatc ataaggatga tgaggaatat cgattctgat tttcatagga gagtctccct
    21541 ttctttattg atatttttct gttaaagact gccaaatctc ttctgtcggc attttcttgc
    21601 ctgtccacag ttgaaaagct tctgcagctt gatagagcaa cattcccaga ccattgactg
    21661 ctggattgcc ctgacttcta gcccatttca aaaacggtgt ttcaaagggt tggtatatga
    21721 tatctgcaac taagagagtt tctggtaaga ctatgttttc aggaacagga gaggattggc
    21781 catccatgcc cacactggtg gcattaacta gcaaatccga ctcggcaatc cttgcttgca
    21841 gttcagaaac atattctaaa gcacacaaat ccactttaaa gcctgtctgc tcctgtaact
    21901 tgtctaggta aggtcttgtt ttttccatag aaacggaacg aacaaagacc gaaatctgac
    21961 tgacgccatc caaaatagcc tgtgccaaga ttgatttagc cgcaccacct gcacccagca
    22021 gggtcatctt tttacctgaa attgtaaaag aaggcaagca cttaaaaaat cccttgccat
    22081 ctgtattata tccaattaaa ttgccattct cattgacaac cgtattaacc gcaccaatca
    22141 agcgcgcttc atcgctcagc tcatccaaat aaggaatcac ctgctcctta tagggcatgg
    22201 acagattgat gccaaacatc tggtagcgac gaatattggc cactgtttct accaagtcac
    22261 tcgcttcaat ctcccaagcc acataagcac cgttggtagc tgtcgcctca aaggctctat
    22321 tgtggatgaa gggagaaata gaatgcttaa taggattggc aacaactgca gctaaacgtg
    22381 tatagccatc aagcttcatc caaaatctcc ctgatttttt tcatgctagc tagagaaatc
    22441 tgcccagggg cactaacctc atccagactg gcaaaagacc aactcgaacc agtcacatcc
    22501 gcagtgatac gagagacctt gcccacctta cccatagaaa tggtcacata ttcctgttca
    22561 ggattgagcg ttttaaagcc tcgtgtatag ttcatcaagt ctaagacatc ctgctccgtg
    22621 tgagccatca ccgcaacctt aacaagtttt ggatttagga tcgtcaactc tgacaagatt
    22681 tccatcatgt tctcaggtgt ttcttggaaa ttatggtaac tcaaaacaag atttgggaag
    22741 tccagcattt cctcaaaaac atccttgtag ctatagtact caaaatcaat atagtctggt
    22801 tgatagagtt gcgcaacttc cttgattaga tggatatact cttctggaga aaggtcgatt
    22861 tctccacctt cggagcgagt tcgtagcgtg aaaaccaact cacggcctgc gaatttttca
    22921 aaaatggctg gagctacctg caaaatcgct tctttaggca gatagtcggc acgccattca
    22981 atgatgtcgg catccaggta cctcgtggca tccagagcct gagcctcctc taaacttctt
    23041 ggcattactg aaacgattaa tttcatttac taaccttcat actaatcacc ttgaggtaat
    23101 tactactttc atctttttta ttataggcaa aatctgctgg aagaccatat ttgtttaaaa
    23161 tctggtaact tcttcctgca aagcctttat caatttgttc tgtaaatttc tgacgggaaa
    23221 cattggcagc attggtactg gcaatgataa tccctcccgg atttaaaatc tcaagactct
    23281 gggaaatcaa cttgtgataa tccttggcca cagagaaagt ttgtttttta ttccgagcaa
    23341 agctaggcgg atctaggaca atcacatcgt aggtcaagtt tttgcgtttg gcatatttga
    23401 aatactcaaa gacatccatg actataaaac gacgctcgtc tgtgctgagc ccatttgcct
    23461 gaaaatgcgc ttgagacaat tctcgtgaac gtttggctag atcaacagaa gttgtctggc
    23521 tagctcctcc catggccgca gctactgaaa aagccgctgt gtaggaaaac atattgagca
    23581 aggatttacc catagccaag ccgtcaacta aactaccgcg aacctcatgc tggtctagga
    23641 aaattcctgt catcaagcca tcattcataa agacttgata caggacacca ttttctaaaa
    23701 cagtgaaaaa gtcaggtgct tcttgaccat aaacatgggc agattcatag tccaaaccct
    23761 taaagcggat tttctcataa gcccctaaaa cctcagggaa aacctgtcta aaggcttctg
    23821 atatagtctg acgaatctga taaacataag agttatacca agaaaagacg gcgtagtcgc
    23881 cataaaggtc cactgtcaga cccccaaagc catctccctc ttgattaaag agacgaaagg
    23941 cagttgtcaa atcatcttga tagtaggcgt ttctcttttc tttggctttt ctaaacaacg
    24001 tttcaaagaa agcttgattg aaggccacct tgtctttgct gacaaaccag cccaagccct
    24061 tgttttgctg agaaaggtag gcagtcccaa gaaagtttcc ttcctgaccc tgcacctcta
    24121 cttcctgatc cttaagattg acattctcaa gatcactggc ttctagtaaa actagcccct
    24181 tagcaagctt cttttcaacc cttttgctga ctcttattct attcataact accattatat
    24241 caaactttta gacaattctc aaaaaagaaa ctacccttgc ttttttactc ttcttttaaa
    24301 aaatggtata ctagacttcc tgcaaaacta ggaagtaaat gtgtaagaat cacaataaaa
    24361 aatgctcttc cgtcttggag gagcatttct ttttatcaac gaaaatcaaa taacaaacta
    24421 tgaaactagc ctcaggttaa ctgtgagatt ataggtagag aggttgaatc agcaatatgt
    24481 gtctgtcaaa tttagtgaca aaggtagtag aagaaagatg aagaaataaa tctgcttcag
    24541 tagatatctg gaaaatttga ttttatagaa aagccttttg ttacaaactc aatatactat
    24601 caataaataa tattatagaa gcaacaataa ttaaaatttc acctatttgc atcattctat
    24661 ttcgaactct aaatatatgt tctatcaaaa atacttggat cacacacatt ataggaatta
    24721 acgtttttga aattgaaaaa tatcccaata aataaactat aaacaacaat aatagaacta
    24781 tattatattt cttattcaaa acattcctcc ctatattttt gattaccaat cttaatcatt
    24841 tacaactaca ttctaacaaa ctataaaagc gtttgtcgaa ttgaatttat caagcaagca
    24901 accaactatc tcatcttttt tctatttctg ccaatatgcg tgacaggtaa taatgatagc
    24961 caaaaatagc aagagcaagc aagacgataa gagctcctac tcccaagttg atggcaagga
    25021 taggggagag agactgaacc aagaatatgc tcccaattac aagggccatc aggattgcac
    25081 tataaataaa caataaaact atggcgacta tgccatttga acgattcacc aggtccgtaa
    25141 tgctactcca attggttgac agatttttaa cgtccttaaa gtaatggtgg caagaaagga
    25201 tgacactggc aatgatccag actacaagaa ggtaaatcat cgaaaggatg gacaagccta
    25261 gatatagaga aagaccgagc aaagtcagaa ctggtaaaaa ggactgaaca gcaaagataa
    25321 tccaaaattt cactttcaca taacgagcaa agtcaaaggg taaactcttc agaaaatcaa
    25381 cattttccct ctccaaggac aaggcaattg aatgcaggct ggtgatattg ttattgacaa
    25441 ctgctataaa cactcctaca aaaaacaagg gtaaccagta tggaggatga atgtctggaa
    25501 ctatctgaga atctcggatt ttggaaatca gactgatcat catgagataa ggaaggaaag
    25561 cacttgtaaa aagcactgta atcacaccag tcccctatcc caagagggtg aggtggtagc
    25621 gtaaaaccat acggaaaaag ccctttttag tagttgaaat cctctccttg ctgcgacgtt
    25681 cttttttgac cttctcctca ctgttaagca ggatcacgtc ataaaaacga ggaaggacct
    25741 tctttttggt cagataaagc aggaagagag ttagtcctat ccaagcgagc agacccacta
    25801 aggcttctgt cgaaaaaggc tccactgcta ttttgtaaaa gatatgaaga ggataaagga
    25861 gaaatggaat gtctctaact ttgtcaacaa tacttccaaa agtcgactga agaaagaaga
    25921 taaatattaa aggtatgaga actcctatcc caatcatcac attcgaaaaa atagactgat
    25981 actttctgaa gaccctagtc tgagccaaga aatgtactgc cactaccgtc actaaagtaa
    26041 cagagacaaa taataaggtc aaggacagta gcatcaaagg caaacccagc caaagagaag
    26101 gagctagact aatatagagg gctagaaaat aagctaggat tggtacaatt ccagttagag
    26161 ctggcaagag gacagacaga cctttggcca ttataatctc tgattcttta aaggcatagg
    26221 gcctatagga ggccaggtcc ttactctcat aaaagacatt gtaaaaggca gtgaaagaag
    26281 ttgaaaaggc cagcaccagt aaaatagcaa ccatcgagct aaaataaata ggtatttcct
    26341 caaaaggaaa atgaatggct atattactaa aacagatgag catcaagaga ctggaaaaaa
    26401 tgtaagaact taggactcta gcagaaacat ttactttttt cccaggattc ttagcctgct
    26461 tctttcgtag attagccaga ttagcttctt gagatgaata gaggatattg atatcaacta
    26521 attttttaat gaccttgaga cgcatccgca acctcctctt ttctaccagc aagactaagg
    26581 tagatacttt ccaaaaactg gtctgggtgg tctttcctca agttctctac actaccacaa
    26641 tagatcaaat gccccttttt caaaatagca atccgatcac agacttgctc ggctacctca
    26701 aggacatgag ttgaaaacaa gaccgtcttg cctttttgtg catgttcctt catcatttgc
    26761 ttcaaatcaa aggcggcctg gggatccaaa ccagtcaagg gttcgtccaa aacccaaata
    26821 tcaggagcag acaagagtgc cccaatgaca aagactttct gacgcattcc gtgagaaaga
    26881 gtttcaataa cctgatagcg gttttcagca aaatcaaaaa cgttcaatag cctagctaga
    26941 ctagtctcca agtcagagct agtcagatca taggatgaag cgatcaattc ccaaaattca
    27001 ttggccgtta agcgtaaaaa taagtcaggc gagtctgcta cgtagccaat ctttcgtttg
    27061 atcgccaagc gattttccga taactcctga ccgtctacca aaatacgacc actgctgggt
    27121 gaaatgatac tgactaggga ttttatggtg gtcgattttc cagccccatt atgaccaatc
    27181 aagcccataa tctctccatt ttcaatctgc aaattgagat tactcaaggc ctctttatca
    27241 ccatacaact tactaacatt ttgaaattca atcatgggac aactcctatc tttatctgta
    27301 ttatacatcg ctatactagc actttgatac aaaaaaatca atactttatt ttaagtagtt
    27361 aaaatagttt ccttctatct tacgcaaacg tttgcgccga gagatacttt atgatagaat
    27421 aaagaacaag attgacaagt aagaggaaac atcatgcaaa atcaaacact catgcaatac
    27481 tttgaatggt atctgcccca cgacggtcaa cactggacgc gtctggctga aaatgctcca
    27541 cacctagctc atctggggat cagtcacgtc tggatgccac cagccttcaa ggcaaccaac
    27601 gaaaaagatg tcggctatgg ggtctatgac ttatttgact taggagagtt caaccaaaaa
    27661 gggactgtcc gcaccaagta tggtttcaaa gaagactatc ttcaagccat tcaagccctt
    27721 aaagaacagg gaattcaacc tatggccgat gtagttctca accacaaggc tgctgccgat
    27781 aacagggaag cctttcaggt tatcgaagtt gatcctgtag accgtacagt tgaacttgga
    27841 gaacccttca ccatcaatgg ctggactagt tttaccttcg atggtcgcca agatacctat
    27901 aatggcttcc actggcattg gtaccacttc accggtacag actacgatgc caaacgcagt
    27961 aaatctggga tttatctgat ccaaggggac aacaagggct gggctaacga ggaattggtc
    28021 gataacgaaa acggaaacta cgactacctc atgtatgccg acctagactt taaacatcct
    28081 gaagtcatcc aaaacatcta tgactgggct gattggttca tggaaacgac tggtgtagct
    28141 ggtttccgtt tggatgccgt taagcatatt gactctttct ttatgcgcaa cttcatccgc
    28201 gatatgaagg aaaaatacgg tgacgatttc tatgtttttg gtgaattttg gaacccagac
    28261 aaggaagcca atctggacta tctcgaaaaa acggaagaac actttgacct tgtcgatgtt
    28321 cgtctccacc agaatctctt tgaagccagt caagctggcg caaactatga ccttcgtggc
    28381 attttcacag atagcctggt tgaactcaag cctgacaagg ctgtgacttt tgtcgacaac
    28441 cacgataccc aacgaggaca agcccttgag tctaccgttg aagaatggtt caagccagca
    28501 gcctatgccc tcattttgtt acgccaagac ggccttccat gtgtctttta cggagactac
    28561 tatgggattt caggccagta tgctcaagaa gatttcaaag aaatccttga ccgcctccta
    28621 gccatccgaa aagacttggc ctatggagaa caaaatgact actttgacca tgctaactgt
    28681 atcggttggg tacgttcagg tgctgaaaat caatccccaa tcgcagtcct tatctcaaat
    28741 gaccaagaaa acagcaagtc aatgtttgtc ggtcaagaat ggactaatca aacctttgta
    28801 gatttacttg gtaaccacca aggtcaagtt acaattgatg aggaaggtta tggacaattc
    28861 cctgtctcag ctagatccgt aagtgtctgg gcagtcaata ccatctaata gctcataata
    28921 accaagctag gtccaagcgg atttggcttt tttgtattca caaaaagacc tacccaaatg
    28981 gatagatctt tacttgatta caatttacct gctactgcat ccaacaattc ttggatctta
    29041 gcttggttgc ttcctcctgc catggccatg tctggtttac caccaccacg tccatcgatg
    29101 attggtgcta attctttgac aaggtttcct gcatgaaggt cttttgtctt gcttgctaca
    29161 aggacattga ctttgtcacc gatagcggca actaggacaa gaagatcaga gtagtctttt
    29221 tgtttccagt tatctgcaaa agtacgaagg gcaccggcat cggatacaga cacttgacta
    29281 gcaatgtaac gatgaccgtt gacttcctta gcatctttga agatatcgcc tgcggctgca
    29341 gctgcggctt tttctttcaa ctcagcattt tctttttgaa gttgacgaag ttgttcttga
    29401 agtccttcta ccttgtgagg tacttccttg acttgaggtg ctttcaaggt tgctgcgaca
    29461 gctttaagag catcctcttg ttcacgatag gcttcaaagg cttccttacc agtcactgcc
    29521 aagatacggc gagttcctga accgattcct tcttctttga caattttgaa gagaccaatc
    29581 tcagaagtgt tgccaacatg agtaccacca caaagttcaa tagagtagtc accgatagtc
    29641 acgacacgaa cttccttgcc gtatttctca ccaaagaggg ccatagctcc catttcttta
    29701 gcagtgtcaa tatccgtttc aactgtcttc acttcaagtg cttcccaaat tttctcgtta
    29761 acttgctgtt caatcgcacg aagttcctca gcagttactg cttggaagtg ggtaaagtca
    29821 aagcgaagga attcaacttc gttaagagat cctgcctgtg ttgcgtggtt tccaaggata
    29881 ttgtgaaggg cagcgtgaag caaatgagtc gcagtgtggt ttttcatgac acggtgacgg
    29941 cgattgctat caattgccaa ggtatattct tggttcaagg caagcggtgc aaggacttca
    30001 actgtatgaa gggcttgacc atttggggct ttctgaacat tggtcacagt agccacaatc
    30061 ttacctgact catccaagat ttgtccgtag tcagctacct gtccacccat ttcagcataa
    30121 aatgacgttt ccgcaaagat aagagaggca gttccttctg aaacagctcc tacttctgca
    30181 ttgtcagcaa cgatagctac caatttagaa gacaattggc tagtattgta gttgaagaca
    30241 ctttctacag tgatgttttg aagagtttca ttttgcatac ccattgagcc acccttgaca
    30301 gctgacgcac gcgcgcgttc ttgttgttct ttcatggctg cttcaaaacc ttcacggtct
    30361 acagtcatac cagcctcttc agcaatttct tcagtcaatt caactgggaa cccataagta
    30421 tcatagagtt tgaagacatc tgaaccagcg ataacagatt gacctttttc tttcaagtct
    30481 gctacaatgc cttgggcaaa gtgttgacct gagtgaaggg tacgggcaaa tgattcttct
    30541 tcgctcttaa cgattttctc aataaagtca cgtttctcaa gcacttctgg gtagtagctt
    30601 tccatgattt ttccaacagt tggaaccaat ttgtaaagga aaggctcgtt gattcccaat
    30661 ttttgaccat gcatagaagc acgacggaga agacgacgaa gaacataacc acgaccttca
    30721 tttcctggaa gggcaccatc accgatggca aatgaaagtg aacggatgtg gtcagcgatg
    30781 accttgaagc tcatgttgtc gccatcttgg tcataaacct taccagacaa tttctcgact
    30841 tcacggataa tcggcatgaa gaggtccgtt tcaaagttgg tcttagcccc ttggataacg
    30901 gccaccaaac gctccaaacc agcgcccgta tcaatgttct tatgtggcaa ttccttgtat
    30961 tcgctacgag gaacagcagg gtctgcgtta aattgtgaca aaacgatgtt ccagatttca
    31021 atataacggt cgttttcaat atcttctgca agcaggcgaa gaccgatatt ttctgggtca
    31081 aaggcttccc cacggtcaaa gaagatttct gtatctggtc cagaaggtcc cgcaccgatt
    31141 tcccagaagt tgtcctcaat tggaatcaag tgacttggat ccactcccac ttcaatccag
    31201 cggttgtaag aatctttatc gtctggatag taggtcatgt aaagtttttc agcagggaaa
    31261 tcaaaccatt cagggcttat caaaagctca taagcccaag tgatagcttc gtcacggaag
    31321 taatccccga tagagaagtt ccccaacatt tcaaacatgg tatggtgacg cgcagtcttc
    31381 cctacgtttt cgatgtcgtt ggtacggata gccttttggg cattggtaat acgtggattt
    31441 tcagggataa tggtcccgtc aaagtatttc ttaagggttg ctaccccaga gttgatccac
    31501 aaaagagttg ggtcatttac aggaaccaaa cttactgatg gttctactga gtgacctttg
    31561 gtcgcccaga aatcaagcca catttggcgt acttgtgcac tagatagttg tttcatattg
    31621 tctccttatt tacttgttta atgtgattgg ctttccagca tttccacata gtcaatcgcg
    31681 acacagaggg aaatgactag gtctgcataa gcgtcttcaa gaaccgttac ggtataggta
    31741 gaggtcagat ggaagagttc cttcttaatt tccgcaatca actgatcgcg atcatccagc
    31801 aatttgaaat tcaaatccca gatattgccc tcgatacgaa gacctagatt atcaaactca
    31861 tacttatctc gccaaaaggt caacttctta cgaatgacaa aactcgagcc atccagaagc
    31921 tgaatctcaa aacgaggaag caaggtcaag atttctttac tgatctgact gacttgttca
    31981 ccagccgcat catagatggt aaaagttttg ggaatcttaa aaaatgatcc ctccacctga
    32041 taggcaattt ctcccctgtc atccttgata gcgaagcgtt cgcctccaag acgaaacttt
    32101 tgtttgacaa gaaatgtttt catcaacacc tccaaaaatc aaaagacaag ctcatatcac
    32161 gaagggcgaa aaaccgcggt accaccttca ttcaatgaac ttgtcattct cttgttctta
    32221 tgcaattgta tgattgagta gcatgacttc ctagcttaga tggctcgcag caccgccatt
    32281 tctctggact aagacaagtg aaaatcaatt ctcaactttc ttattatatc gtttttttaa
    32341 tcttgcgtca actggaaatg atctccgttg aattagacca attccctaca tctctgatta
    32401 cttttccagg atatattttt tcttactgcc gtttttcttt ttatcccaaa ttttcatatt
    32461 actaaacaca gctactagaa tatttccaaa tataaaggtg cctatcaccc aatatatgga
    32521 ctcagttgtt aggtattgtc gatccaagcc atcctttaaa tggaatagta tagcagtttg
    32581 gttaacaatc ataaaggttg gccagaaact tttgttgaaa aaagtagaca ttttcattat
    32641 ttgttgccgc tttctgtaag gttaatactc aataaaaatc aaaaagcaaa ctaggaagct
    32701 agcctcaagc tgtacttgag tacggcaagg caacgctgac gtggtttgaa gagtataggc
    32761 ttagtatact actaggcaag caaataagca aataaacaac tagaatagaa aaagataggg
    32821 ctctaaaaac tgacttctat tccttaaaaa cgaaccagct tgactgattc gtcttcttac
    32881 gtttatctcc tacttccgat acattttaaa ctgtaggaag aggtcgctat atttccctgt
    32941 ccatttatgg tcaaatttct cataaatttc taggtgtttc atggtttcaa catcgggata
    33001 gaaggcctta tcttcctttg tttcctctgg gagcaattcc ttcgctggta tgtttggtgt
    33061 tgaatagccg acatactccg cattttggag agcattttca ggtttcaaca taaagttgat
    33121 aaaggcatag gctgagtctt ggtttttaac tgttttggga atgaccatat tgtcaaacca
    33181 aagattgctg gcctctgtcg gtaccacata acgtagattt tcattttttt ctaacatttg
    33241 gctggcttca ccagagaagg tcacgccgat tgcaacgtta ttctgaatca tatagccctt
    33301 catctcgtcc gcaacgatag ccttgatatt tggagtcagt ttgtagagct tatccactgt
    33361 ctcttccaac tgctgcagat ccttggagtt gaggctgtag ccgagggaat tgagtcctag
    33421 tcccagcacc tcacgcgccc catcaaagag catgatagaa ttcttatact ccggcttcca
    33481 aaggtcatcc caatgctcag gcgcttcatc taccatggtt tcgttgtaga caattcctaa
    33541 ggttccccag aagtaaggga tggagaattt attacctggg tcaaaggact ggttgagaaa
    33601 ctctggtccg atattttcga ttccttcaat ttttgaataa tcaagcggaa ccaagaggtc
    33661 ttcgtccttc atcttgttaa tcatgtattc acttggaatg gcaatatcgt aggtcgttcc
    33721 accctgcttt atcttagtgt acatggcttc gttggagtca aaagtctcgt actgaacttg
    33781 aattcctgtt tcttctgtaa actgagtcaa gagttcagga tcgatatagt ctccccagtt
    33841 atagataacc aatttttgac tatctcgact attgatttta ctatctaaat gagtcgcaat
    33901 tccccacaag acaaggataa tcgctgcaat tcctgctaaa aatgaataga tttttttcat
    33961 gcttgctcct ccttctcacg agagataaag taataaccta caactaggat aatactaaag
    34021 agaaagacta gagcagacag ggcattgatt tctaaggaaa tccccttgcg agcacgagag
    34081 taaatctcga ctgatagggt tgaaaagcca tttcctgtta caaagaaggt cacggcaaag
    34141 tcatctaacg aataggtgaa ggccatgaaa taaccagtaa tgatagacgg agtcaggtaa
    34201 ggaagcatga tttccttgaa catctgaaat tgactagctc ccaagtcata ggccgcatga
    34261 atcatgtcgc cattcatttc cttgagtcga ggcaagacca tcaagaccac gataggaatg
    34321 gagaaggcca cgtgactaga tagaacggtc aaaaagccaa gtgaaaactt gagttgggta
    34381 aagagaatca agaagctagc accaatcata acgtcaggcg caaccatgag gatattattg
    34441 agtgatagaa aggcttcttg gtatttctta cgagactggt agatgtaaat ggcaccaaaa
    34501 gtcccgataa tggtcgctat caaggctgat aggaaggcca agaaaaatgt ctgagccaaa
    34561 atcagcatga gtctcccatc tccaaacatg gtttcaaagt gagtccagct aaaacctgta
    34621 aagctattca tatcatcacc agcattaaag gcatagccaa tcaagtaaaa gataggcagg
    34681 tagaggacca gaaagaccag tcccagataa aggttggcaa attttttcat cgttctctcc
    34741 tttccttagt cacccacatg gtgatgaaca tggtcaggat gagaatcaca ccgatggttg
    34801 aacccatacc atagttgtca ttggttagaa aattctgctc aatagccgtc cccaaggtga
    34861 taacgcggtt cccaccaatc aaacgggtca gcatgaagag actcaaactt gggataaaga
    34921 ccgactgaac cccacttcgc acaccgttca tagatagagg gaagatgaca tgacggaagg
    34981 tctcccactt agttgcacca aggtcataac tagcattgat gagattatta tccatgtcgt
    35041 ctaagacatt gaaaatcggc aaaatcataa aggggagctc gatgtagctt gcgacaaaga
    35101 taaaggaaaa atcggtaaaa agcaactgtt gtgaaccaat tccgataaat tccaagaatt
    35161 ggttaataga gccattttga ccaaaaatcc cgataaaagc ataggcttta aggagcaaat
    35221 tgatccaggt aggaaggata atcagcatga gccagagttg acggtgcttg agacgggtca
    35281 aaaagagggc tgttggatag ctgataagca aggtcacaaa ggtcacaatc cctgcataaa
    35341 gcactgagtt gaaactcatt ttgaggtagg tcaagttttg tgacgcaaag taagatttat
    35401 aattttctaa actaaactgg ccttcaatgt tgaaaaagga ttgtccgaaa atcaagacca
    35461 agggtgccaa tacaaagagg gcaatccaaa gcatgtaggg cactacaaag agtttagagc
    35521 ttgttttctt catctctttc ctcctcgatc gcattgatca gacctgcttc ttgctcttcg
    35581 atttccacgt attcttcgat acgagcatcg aactcttctt cggtttcatt gagacgcatg
    35641 atgtggatgt cttctgattc aaagtccaga ccgatttcct cacccacgat ggccttacgg
    35701 gttgagtgga tcatccattc atttccaagt tcgtcatagg cgataatttc ataatgaact
    35761 ccacggaaga gctgggtgtc gaccttaact tggagtttgc cttcttcagg aagggtaatg
    35821 cgcaagtcct ctggacgaat aacgacctca acaggttcat ttggcttcat cccaccatca
    35881 accgcttcaa agcgtttgcc gttaaattcg accaagtagt cctcaatcat ggtacctggc
    35941 aagatgtttg actccccgat aaaggtggca acaaagtggt tgattggctc atcgtagatg
    36001 tccacagggg ttccagactg gacaatctcg ccatcattca taacgaaaat ccagtcactc
    36061 atggcaagag cttcttcctg atcgtgagtg acaaagacaa aggtaatgcc caatcgttgt
    36121 tgtaattcac gcaattcgta ctgcatgtct gttctcaatt tcaagtccag cgctgataaa
    36181 ggctcgtcca acaagaccac acggggttgg ttgatgatag cacgggcgat ggccacacgc
    36241 tgacgttgtc ctccagaaag tttgcggatg gaacgttttt cataaccttc caactgaacc
    36301 atcttgagaa cttccgctac acgctgctcg atttctttct tatcaatttt acgcaagcga
    36361 agtggaaagg caacattttc aaacacattc atatgtggga acaaggcata ggattggaag
    36421 acggtatgta cgtcgcgctt gttggttgga atatcattga tacgaacacc gtctagcatg
    36481 atatctcctg tcgtcgcatc cagtaaacct gcaataatgt ttaggatagt tgatttcccc
    36541 gaaccagatg cacctagaag ggtgtagaat ttcccttctt ccaactcaaa gttgatgtct
    36601 ttgagaacct tggtgttgct gtcttcaaaa actttagaga cgtttttgaa ttcgataatt
    36661 ggttttttca attggcataa attccttctt tttcatagat taaccgatcg gggctctgtc
    36721 aggtccccac tacctcttgc agggagtaaa accacctgca tacatcttcg ctaccgatag
    36781 gctttcaccc aagatccgga cttctctttc aagcgtaata cctgagtgtt ccttgacttt
    36841 ttcgataacc gattggatca agtcctcgta gtctttggcc gttccatctg cgacattgat
    36901 cataaatcct gcatgctttt ctgacacttc tacgccaccg atacgatagc ctttcaagcc
    36961 agcttctgaa attaactgac ctgcaaaatg cccgactgga cgcttaaaga ccgagccaca
    37021 agatgggtat tccaaaggtt gcttgagttc acgtaggtgc gtcaagcggt ccatttcctg
    37081 cttgataacc tgatgggttc ctggagctag ggcaaattta actgacaaga caactgcacc
    37141 agactcctga atagctgaat ggcggtaacc aaaagccaag tctttagcag acagggtttc
    37201 gatttctcca tccttggtca agaccttaca agactgcaag atgtgagcaa tctcgccacc
    37261 ataggcaccc gcattcataa agacagcacc gccaacgctt cctggaatac cacaagcaaa
    37321 ctcaaagcca gttaaactat gacggagggc aatgcgagtt gtttcaatca agttagcccc
    37381 agcttctgct tcaatggtat agccatcaac agaaacgtta ttgagcttgt cacacaagat
    37441 gacaaatcca cgaatcccac catcacgaac gatgatattg cttgcattgc caagaaccat
    37501 ccaagggata ttttcttggt tggcaaattt cacaaggcga gccaactcaa aacgatttcg
    37561 tggaaagacc aaataatcag cctctccacc tacttttgta taactatagc tatgcaaggg
    37621 ttcctgaaaa cggatatcaa ttccttctaa gatttcaagc attttttctc ttacagacat
    37681 gtcactcttc cttttccaaa attcattcca ttataccatt tttagagaca tttgacgacc
    37741 ataaaaatac cttgtttgga ttttgcataa gaaaaagagg ttcccccctt tttatgattt
    37801 tttacaaaag atttccttgg ttccataggc gaccagaacg agctccagtg ctagaatcac
    37861 ttcaaccaag actggatttg tcaaccagcc tacttggaaa agagatggtg ccagatcaaa
    37921 gaaggcatgc aagccatagg ctgttaggag ataaatccat ttcttctggc gaacagcttg
    37981 gtaaacccaa actgtcaaaa gtaattggaa accaagcgcc aagattcgct caaaaccaag
    38041 caaataaatc tgccagaccg aaagtgactg aatggttttt aacatatttt cagacagtaa
    38101 ttgcataacc tgtggattct gagtttgaac tgccgaaaga acaatgtaaa gattgagtaa
    38161 actagtaagg cctagaaaaa tcaactccaa gccaccatgc cccagtccat aggccaaggc
    38221 gtctgccttt tccaaacttc tctttttctc aaaccatttg aagaaaacaa gacgagccgt
    38281 ttcctcaaaa aatgctgcca tggctaggcc atagataata tagataagcg gatgatcttg
    38341 caagagggca atactaccgt ctttttgagg gtgcaaaatc aagatatgca ccagtttttc
    38401 caaaatctgc gaagagacaa agaaagcgac tgcacccaag cccaagacag ctagattaat
    38461 ctggtatttc tttttggcaa accaaatgct tcctatcaga aaagctagca acagcaacat
    38521 ggtaataatg atatgaatgg tcattttctt ctcctattct gccttttcaa tatctttttt
    38581 catctcgtca acattgaact tagcaaacaa gtattgacgg tcttggactg ggaaacgttg
    38641 gtccaactgg tcaactgctc ccacctcgat aatgccttcc ttgatgacaa aatccatgac
    38701 atgtccaccg aaggtcaaat catctgatat gaagtgcaga tggtagcctg ccacactgac
    38761 cccatggaaa atctcaggcg tccagaaacc aacaatagtc cccgcaacat tgtcacgact
    38821 atattccggt tgatgggttg cgacatcagc aaacttggta tcgggtgttg acttaggaat
    38881 catacgcaca tgcatatgta aaaattcccc ccgaatcttg atagagcgga aaagattttc
    38941 cccatcataa taagactcaa ttcgttcttt caattccttg tctgtcatct caaagcgctg
    39001 gcggaaaatg acctctgcct gatgcggtac cactgcagcg taaggaataa gggcatctgg
    39061 tgacacttcc acaatttctg gctggtctcc tgaccctttg gcctgataag ccttgccatc
    39121 caagacaatc aattccccat caatggaatc caaggttccc aaaccaaggt caccatgttc
    39181 tagcaattct cctactgtca tagtaccacc ataaaggcca gccatcaagg ctccaagagt
    39241 attgtattga aataatttca ctggttcctg cacgttctta tccattcact ttcttgtctg
    39301 ttattctata aatcttactc ctaagtatac cacatttgcc cctagatgtg aacgagagaa
    39361 acgttctaga cattgccaag aaggaaaaaa aagggtacaa tgtaacaaaa tcaagggagg
    39421 tctggaatga agaaacaaag caagtacaaa gaggtcgttt cctatctgaa aaatggtatc
    39481 gagtctggac gatttccgac gggtagtcgc ctgccttcta tccgtcaact gagccttgac
    39541 tttcactgca gcaaggacac cattcaacga gccctgctgg aattacggca cgaacaatac
    39601 ctctatgcca agcctcagag tggctactat gtattagaac aagggcaaca tcaagaccta
    39661 gaaatcgagg ttaccgacga acatgccagt gcctatgacg atttccgact ctgtgtcaat
    39721 gaaaccttga ttggccgaga aaactacctc ttcaactact atgacaatca agaaggatta
    39781 gaagacctaa gacagtccat tcacaaactc ctctttgagc aagctctcta ctgcaaggct
    39841 aaccaactag tactgacttc tggaacccaa caagccttat ttatcctctc tcaaatatcc
    39901 tttcctagac aagccaagga aatcttggtg gaacagccaa cctaccatcg gatgaatcgc
    39961 ctcttgattg cacaggggct ggactatcaa acgattgaac gaggcattga tgggattgac
    40021 ttggaggagc tggaaggcca cttcaaaaca ggaaaaatta aatttttcta caccattccc
    40081 cgatttcact atcctctggg acattcctat tctgagcaag acaaacgatc tattcttaac
    40141 ttagctgcca agtatgatgt ctatatcgta gaggacgatt atctgggtga tttggactcc
    40201 aagaagggcc aaaccttcca ctatcttgat acagaggagc atgtcattta tatcaagtcc
    40261 ttctcgacca gcctttttcc tgcccttcgt attacagcac tcattcttcc aaatgctatc
    40321 aaagaagcat ttgtggccta caaaaatatc ctagactacg acagcaacct cattatgcaa
    40381 aaggccctgt cactctatat tgacagtcaa ttgtttgaaa aaaatcgttt ggctcgcttg
    40441 accaatcatg aatcttacca aaaacaaatc gaggaaagga taactaaaac accttgtccc
    40501 cttcctcatt atcccctaca cgatggttta ttgctagacc tgagacagta tcctaaaatc
    40561 gccagtctca aacacagtca actgggcttg gacttctttg aagaggccta tttgagcacc
    40621 tgtccttatc aatttgccaa ggtgtcccta gacaatctgg aaaatgtttt aaactattta
    40681 aaagcagaat tggaatgaca tccaactctg ctttttctta ttcttcaact tcagttagac
    40741 ttgctgcttt ttcaagatag ctttggtaag ttccttcatc cttaagtttt tggatgacct
    40801 tgtctaccac ttctttcaaa tcatcactat tttttctaag agcaacggca ttggcgtcgc
    40861 cgtccttcat cttcaagctg acagttgcga cagctaagcc agcgttttta gcagcataac
    40921 taagtgcaac aggctcatcc atatgaacag catctatttt tccagcctgc aattcattga
    40981 ctgcttcacc catattagtt agggaagtta attgagcttt tggcaattgt tccttgacca
    41041 ttgattctgg aacagtccct ttttgggctg caatattagc actttctagg ctagttaaat
    41101 ccttgtattt ttccacatca gccttacgaa ccaagaaact aatcttgttt tcatagtatg
    41161 ggattgaaaa atcaaagact tcttttctct cgtcagtagc actaattcct gcaactgcta
    41221 ggtcagcctt accagtttga agactggtca aaacattgtc aaaactcatg cttaagattt
    41281 ccaacttaac cccaagttca tcagcgatag cctgagccat gtcgatgtct gcaccgacta
    41341 cctggttctt tccatcaacc aatgattgaa attcaaaggg tgcatagtca ggactggttg
    41401 ccacaactaa tttccccttt tgcttaatgg cctcaacagc tgactgagaa ccattagaac
    41461 ctgactggca agctactaag aagaaacttg caagaaaatt acataaaaca aatatccatt
    41521 tttttgattt cataaataaa caacctttct gttaattttg tataattata acgatatcca
    41581 agttacttgt caagtgtttt ttaaattttt atctcaaaaa tattttttcg ttcaaaaaaa
    41641 ggagccatca gttgatttca agctcctttt tatacagaat taaactattt tatagttcga
    41701 caatcttacc tgtttcaaag tagacaaccc attcacagat atttttagca tagtcaccga
    41761 tacgctccaa gtaggaaata acttggaaat aatcacgacc cgtaacaatg gcttctggat
    41821 ttttcttaat ctcttcagtc gcaaggtcac ggatagtttc aaaatagtgg ttaatttgct
    41881 catccatgga ggccacccgg tatgcgtcgt caacagaacc attaagataa agatcaagtg
    41941 ctgcttccac aacgctttta acttcacgtc ccattttttt aatttcttcc tctacagctg
    42001 ggatgcgttc ttcccccttc atacggatgg ttgcctgggc aatggctaca gcgtgatccc
    42061 ccatacgctc cacatctgat acagccttaa ggacagtcaa gactgtacgc aaatcttgag
    42121 agactggttg ttggagtgcg atcatttcaa atgatttctt ttccagtttc acttcgtatt
    42181 catttacttc tgcatcatct tcgatgacct cttttgccag gtcacggtca tgcgtgacaa
    42241 aagcacgtac cgtacgattg atttgtgaga gcacttcttg tcccatagcg tagaactggt
    42301 tatgtaattt ctctaaatct tcttcaaatt gagatcgtaa catctttcat ctccttatcc
    42361 aaattttcct gtaatatagt cttccgtttc cttgtgttgg ggatcaagga acatctgctt
    42421 ggtatcatta aattcaatca aatctccatc taggaaaaat cctgtcttat cagagatacg
    42481 tgaagcttgc tgcatggaac gggttaccag aagcatggtg tacttgtctt ttagaccata
    42541 caaggtttcc tcaattttac cagctgaaat cggatccaaa gccgaagttg gctcatccaa
    42601 gaggatgatt ttaggactag ttgccaagac acgggccacg cagacacgct gctgttgacc
    42661 acctgacaat ccaatagctg aatcatatag acgatccttg acctcatccc agatagaggc
    42721 accttgcaag gctttttcta cggcttcatc cagaacctgc ttatccttaa ttccattgat
    42781 acgaagcccg tagacaacat tctcatagat agtcataggg aaaggattag gttgttggaa
    42841 aaccattccg atttccttac gtaattcaac cgtatctgta cgcggactgt agatgttgtg
    42901 accattgtac accacggatc cagttgtggt cacctctgga ttgagatctc ccatgcggtt
    42961 gagagacttg aggagggttg acttccctga tccagatgga ccaatcaagg ctgtaatttc
    43021 cttaggttgg aaagataggg aaacactatt caaagccttc tttttattat aatatacgga
    43081 caggtctgat acctgtaaaa tcgcatctgt catacggttt cctttctaac caaagtgacc
    43141 agatacatag tcattggtgg actgtagctt ggcattttgg aaaatagttg cagtcttgtc
    43201 atactcaatc aaatcaccca agtaaaagaa gcctgtatag tcacttgcac gagcagcctg
    43261 ctgcatatta tgcgttacaa tgatgatggt aaagtttttc ttgagctcaa acatggtctc
    43321 ttctagttgc atggtcgcaa tcggatccaa ggctgaggct ggctcatcca ttaagaggat
    43381 atctggctta acagagatgg cacgagcgat acagagacgt tgttgctgac cacctgataa
    43441 ggtcaaggct gacttgtgga gatcgtcttt aacctgatcc cagagggcag cctgacgaag
    43501 ggaggtttct acgatttcat ctaggacttg cttatcctta actccagcac gttcatgcgc
    43561 aaaggtaata ttacggtaaa ttgacttagc aaatggattg gggcgttgaa aaaccattcc
    43621 aatgtgttta cgcatttcat aaacgttgat ttctggacgg ttgacatcaa ttccacgata
    43681 gagaatctgc ccagttactt tagcaatatc aatagtatca ttcatgcgat tgagactgcg
    43741 taagtaggta gatttccccg atcccgacgg accaatcaaa gctgtaattt tatttctttc
    43801 aaattgcata tcaatcccct taatggattc atttttacca tagtaaacat ggacatcctt
    43861 agtagaaagg gctacttttt cttcaggaaa ggtaaggata tgcttctcat cccagttata
    43921 tgttgacatg gcttctcctt taggcagcgg ttaatttctt gtgtagatag cttccgaact
    43981 tacgagctcc aaagttaaaa atcaggataa agatcaggag cacagcggca gaacctgctg
    44041 atacaatggt tccatctgga atagtgcctt cactattgac tttccagata tggacagcca
    44101 aggtttctgc ttgacggaag atagagatgg ggctagtcac actgaggata ttccagttag
    44161 accagtcaag agctggcgcc gattgccctg ctgtatagat cagagctgca gcttcgccaa
    44221 agatacgacc agatgccaag acgacacccg ttacaatacc tggaagcgct tctggaataa
    44281 caacatgaac cactgtctcc cagcgagaaa tcccaagagc cagaccagcc tcacgttggg
    44341 tatggtgaac gtgtttcaaa ctatcctcta cattacgcgt catctgaggc aagttaaaga
    44401 ctgtcaaggc caaggcacct gaaatgattg aaaatccata ctcaaactgg actacaaaga
    44461 tcaagtaacc aaagagaccc accaccactg atggtaaaga ggacaagatt tcaatacaag
    44521 tccgcacaaa gttggtaaca ggaccttttt tagcatattc agccaagtaa atcccagctc
    44581 ccatagaaag aggtacagaa ataatcaagg taatgaccaa taggaaaaag gaattgtaaa
    44641 gctgaatgcc aatcccacca cctgcttgaa aagcagaaga ccttccagtc aagaaagacc
    44701 aagagatatg gggcaagccc cgaaccaaga tatagagaat caaggaagcc aagattgtca
    44761 caatgatgct agcaatcgta tagaggacag ctgttgcaag tttatctaat ttcttagcgc
    44821 gcataatttt tctttcctct ttctttcgta atcaatttaa tcacactgtt aaaaactaaa
    44881 ctcatcaaga gcagtaccaa ggccagtgac cagagaacat tattatttac agttcccatg
    44941 acagtgttcc caattcccat agttaatata gaagttaaag ttgcagctgg tgtggtcaag
    45001 gaagttggga taacagctga gtttccgaca accatctgga tagctaaagc ctcaccaaag
    45061 gcacgcgcca tcccaaagac cactgcagtg aaaataccag aacgggccgc cttcaagatc
    45121 acacgccaga tagtctgcca gcgagtggct cccatagcga aacttgcctc acgataataa
    45181 cgaggaaccg cacgcaagct atccgttgtc ataaaggtta cggtcggcaa aatcatgaca
    45241 aagaggacgg aaatccctga caaaatccca aaaccagtcc caccaaagac actgcgaaca
    45301 aagggaacga cgacttgcaa gccaataaat ccgtacacta ctgaaggaat cccaaccagg
    45361 agttcaatag ctggttgcaa aatcttcgcc ccttttggtg atacttcggt cataaaaact
    45421 gctgcaccaa tagcaaaggg tgttgcgata agggctgaga gaatggtaac gataaaggaa
    45481 cccaaaatca taggaagggc accaaattct ttactagaag gattccaagt tcctcccaaa
    45541 agaaagtcaa agatattcac accattgaca aagaaggtcg acaagccttt ttgcgctacg
    45601 aaaaccaaaa tcatggccac aaggatgact atcaaagaaa gacaggcaaa ggtcaaacct
    45661 tttcctaatt tctccagacg agaattcttt gatggaagca acattttctt agctaattct
    45721 tcttgattca ttattgtctc ccttccaaca ctgtcacagt tccggcagca tctttttcaa
    45781 ccttcatttc cttaatcgga atatacttca atcctttgac aatcccttct tgggtctcat
    45841 ccgagagaac aaaattgaga aattctgcag ctaactcatt gggctgcccc aatgtataca
    45901 tatgctcata agaccacaag ggccaattat tgctacttat attttctgga cttaagtcat
    45961 agccattcaa cttcatgctt ttgaccgaat catctatata ggtaagagat aaataagaga
    46021 tagctcctgg actttttgat acgattgatt ttaccgctcc atttgaatcc tgctcctgac
    46081 tttgcatggc agactgacct tccataatga cagtatcaaa ggtagcacga gagccagagc
    46141 cggctgcccg attgataaca gagatgggta agtccttacc accaacctct ttccaattgg
    46201 ttacctcacc tatgaagatt tgacgaagtt gctctgtcgt taggttatca acatcaacct
    46261 ccttattgac aatcagagcc aagccagcta ccgcgacctt gtggtcaaca agagcagaag
    46321 catcaattcc gtctttttcc tcagcaaata catctgagtt tcctatatca actgccccag
    46381 actgaacctg ggacaagcct gtaccagaac ctcccccttg gacattgacc gtttttccaa
    46441 catggatcgt gccaaattca tctgccgcta cttcaaccaa gggttgcaag gcagttgagc
    46501 caacagccgt tatggattct ccacgatcaa tccagctagc acagcctact aaacaagccg
    46561 tcagccaaaa agcgataaga gacagagcaa gcttttttct ttttttcact gtttttctcc
    46621 tcgaaaataa ttatgaatac tgtgaatttt ttaagtagtt ctttatgagt tgacgcatga
    46681 attcttacca aatttctgcg caattgatta tttatataat ataggctata ttactctttc
    46741 ctaacctcct tttttcatat gtggataaaa tctcttgtct atcccttccc ccattgtcac
    46801 ccattatagt catttcgtgt ctctttttcc cctttttaat gcaagggaaa ttactctcct
    46861 tagatgataa tccaaaagct agaaaggtat ctcaaatctc tctactctcc cagactagtt
    46921 tacaactaaa aggaaaagat tctattttat gagaaatcta gtttacaagc ggtaagaacg
    46981 ctaataacta aacttcttgt actctttgaa aatctcttca aagcagtgtt ttgagctatc
    47041 tatggctagc ttcctagttt gctctttgat tttcatcgag tagtaaaact acatgtgatg
    47101 gcaatcaaga tatcaagaat catcctacta aaaaaatcca tactttcact ataacataga
    47161 ataagatatt tgactagcat tttcatttga atctgaggcc ttttggaaaa taatttttca
    47221 aaacatttcc agtaaccttt gcaaagccca agccattgcc tttaaccaaa acttggtacc
    47281 aaccatttgg cagactttct gccagctgaa cggtttctcc agccgcatac ttgacaaact
    47341 cttcttggcc aatttcaacc gactgttcga cctgactcgg tttcaaggct aaaccaagag
    47401 cgaaactggg ctcaaagcgt ttcttcttaa aagtacccag atgcagtcca ttgcgagcaa
    47461 tcttgagctt ccctaaatct ggcaaaagtt ctggcaagag ataaagctgg tctccaaaaa
    47521 tctgcaagat acccggtaga ttgaccttca aatggttttg ggcaaattcc tgccacaagg
    47581 caacttgttc acggctgagg ttactcttac ttgccttaaa tttaggagct ggattgttac
    47641 ccttaaactg tagatgggca acaaactgac cctctccctt aaactgatga gggtacatcc
    47701 gagccgtttc tggcaggtca ataccagcta ccattccatt gatatgctct actggcaaca
    47761 agtcaaaatc atactcttcc agcaaccaat tgacaatctc ttcgttttcc tcgggtgccc
    47821 aggtacaggt cgaataaacc agacgaccac cttcagctaa catggtcact gcatcctcca
    47881 gaatttctct ttgcaagcta gcacattgac tcggataatc taagctccaa tagtccatag
    47941 catcaggttg cttacgaaac attccttcac cagagcaagg ggcatcaaga acgattaagt
    48001 caaaatagcc tttaaagacc ttgaccaagc ggtcggcaga ttcattggtc accacgacat
    48061 ttgtcgctcc aaaacgctcc atgttttcaa ccaaaatctt agcccgtttg cttgaaattt
    48121 cattggaaac aagtagcccc tcccctgcta gataggctgc cagttgagtt gatttgcccc
    48181 ccggtgcagc agccaagtcc aagaccttca taccaggact gggttgggct acttgagcca
    48241 ccatttgagc agcaggttct tgcgaataaa ctaaacctgt agcatgctca ggcgatttcc
    48301 ctgaaacctt cccatagtgg ccccaagggg tttgagtaat ggcatcagaa aaggaaagtt
    48361 gctcttcttt taagggattg acccgaaagg ccgaaaccgc ttcctcctca aaagaggcaa
    48421 gaaaatctct tgcctcatct cctagtattt ctttatattt ttcaacaaat ccttctggaa
    48481 atttcattta agttcttttc ctttcgtaaa tataggactg aatttcctcc tgcatctcaa
    48541 gaggcaccat catgaccggc tgtctggttt gaaaatcagg agcttcacca aaaagggtca
    48601 caacccgata gcccagactt tcccctaaaa tactagctgc ggcataatcc catggttgca
    48661 gataggtgag ataggtcaac aaacgccctg acaaaatctt ggcaaaacta atggccgcac
    48721 ttccatagac acgaacacca agaaccgctc ggctcaaatc agccagcccc cattcattgg
    48781 tttccagcat accactattc cctgcaatga gaaaatctcc aagtggttta gttttaaaag
    48841 aagctagggg cctatcattt agacaaactg gaaattcccc accaccgtgg taacaatccc
    48901 ctttgaccac atcataaatc agaccaaact gtccctgacc attttcaaaa taagccatca
    48961 taacagcaaa atcttcctgc tgggctacaa aattattggt accatcaatg ggatcaatga
    49021 cccaaacctt gccctcttga accgaggctc gcagacaacc ttcttcagca caaatcttat
    49081 cctcaggata acgggacaaa atctcaccaa ccaagagttc ctgaacttct ttgtccagtc
    49141 tggtcaccaa atctgttgga gaggacttgg tttcaacacg caagtcttcc tgcatatggt
    49201 caagaatgta ctgacctgct ttcttaacaa gctctttagc aaattcaaat ttacttttca
    49261 agagaaatct ttcctttccc tttttctttg gcagcctgaa ctgctcggta aagtgaatag
    49321 ccactaaccg tttcaaattc tcgtcccaaa cgtttctctt cgctcttgct tggcacgacc
    49381 gctttgaatc ccttatagga gtccagtaac tttttagcct ctactttgcc ttcataggca
    49441 gcttcaacat cattaaaaaa agaaagcact gaagcaagtt cttcagtgct ccacgacaaa
    49501 tctagtgggt aactatactg tttgttcatt aactaatacc agctctcatt cttgcttctt
    49561 ttagttcttg cttacgataa ctacgaggga gaaaagcacg aatctcatct tcattaaaac
    49621 cgatttgcat acgcttggca tcaataataa ttggacgacg caaaagacta ggatactgct
    49681 caatcaaatg aagcaattcc gataccgaaa tactctctac atcaatattc aatttttgaa
    49741 aaatttttga acgagttgaa atgatgtcat cagtaccatt ttcggtcaag gaaaggatgt
    49801 gttgcaattc ttttcttgtt aaaggactgg tcataatatt gtgttccaca aagggaacct
    49861 tatgtttttc taaccaggtc ttagccttac gacatgatgt acagctcggt gatagaaata
    49921 gtgtaatcat gcttttctct tcttatctat actttgctac ttctattata caaaaaaata
    49981 aggcgcttga ctagggattt ttagaaaaaa agcctatttt ttcaggaaaa ataggctgtt
    50041 tgcgaacgat tgacacaatt ggatttggtt aattcactct taacgatggt tttaaacgat
    50101 atatatattt atatatgtaa attaaaaaca tctttccttt cacttcctac gacttttcag
    50161 acacagatag ccaaagaagc tttcatagag ggcaaaaaag aggaggaagg catgaagaaa
    50221 gaaggtctct ggcaaaatca taataacagg atccttggct ggatcaaaaa gccaggtatc
    50281 atctcccaca aagagaattt gatggaaaag agtaaagaat tggtcaaaac caatcaaaac
    50341 tcccccaagt ccaatcatca caggtaagac tactagagcc aggagacttt ttcgataaag
    50401 agacaaaaag tcctttttca caatcctatt gacaaagaca tagaaacttg gcagtgtcac
    50461 tagagctact agctgaacca aatgaaagag attcttgacc actgcgaaat ggtgcaaacc
    50521 agctgctgac gaacgaaaat caggcatctg taagacctga ctaaaaggat tggtcagata
    50581 attcatcaag atatgaaaat tgtattgaat ggtttctggt tttagataga ctcgattcgt
    50641 taagtttagc cactgaatct ccataggata gaaaatccaa gccagataaa tggtcagaag
    50701 gattgagagg gagaggagaa agagcataga gccccaaaag gtcaatttag ttttcatcaa
    50761 aatcccactc cgcaaggcta gaaaccacat gtgtcggtgc gattggcagg ccagctactt
    50821 cttctgcctt ggtaaaacct gtcgtcacca agagcgttgg aatgccattg tcaatcccag
    50881 cccggatatc agtcaaataa ttgtccccaa ccatgattaa ctcttcacgt tccaaaccta
    50941 agtgctcaac tgccttgtcc ataatgatgg cattgggttt tccgatataa accggcttca
    51001 ctcgtgtcgc tacttcaagc agcgtaatca gtgagccagc acctggcaaa agaccacgtt
    51061 ccgtcgggat gttgaggtca ggattggttc cgataaaatg ggcacccttt tgaatagcaa
    51121 gagttgctgt ggcaaatttt tcatagtcga cttgccaatc cagaccaact accacgtagg
    51181 caggtttttc cttgtcttcc acataaccag ccgccttgat ggcttccttg agtcctgctt
    51241 ctccgacaac atagacggtc ttttcaagcc ccaaatcatt catatagtcg atggttgcca
    51301 aagtcgctgt gtagacagtc gataggggcg tatcgatatt aaaattctga gccaacatct
    51361 ccttaacact ctctggagtg cgggttgtat tgttggttac aaagagatag ggaatgtccc
    51421 gcttttgcaa ttcatgaaca aaagtctctc cagcagggat ttggtctttc cccttataaa
    51481 tggttccgtc taaatcaatt aaatagcctt tatatttcat ctatttctcc ctaagccttt
    51541 tttatttctt gccaagtaat gattgcttgg gcattgataa ccccatcact tgtaatttca
    51601 tgcttgcttt ccagtccagt ccgttcaaca gccgatgtaa tcaccccacc tggtcgaact
    51661 tccttgacat acttgaggtt gattttcttg ggaatatagt gggtcaaaaa atccgctccc
    51721 atgacctcaa aaatccagtc taagtattta ctgttattga catgaccatt catatccaag
    51781 tcgtaaaaac gaacatggta atccttgctg atcgactctt ccaaggactc atacttcggt
    51841 ccacggataa gttttttatc aaaatcagac tggtaaggag ccacaatctc aggttcaaca
    51901 gcatggactt ttcgactgtc gcggtccatg agaacaaagg tcgccatcat atggatgagc
    51961 tcctgccccg cttcattata aatagtaaag cgacggtagc aaaaaagtcg attgtagctc
    52021 aaggcttccg tttcgatggt aatttcttcc gcaaaacgag gcaaacgaac cacctcaata
    52081 tcatattcta cgataatcca gaccagatta tagtcttcca aaatggcctt atcactaact
    52141 cccagttcaa tcgactgcat ccctgaaact tgcagtgaca gcaaaattac atctggaagt
    52201 ttgatatgac cgttcatatc agccatatca aaaggaattt tcattttcat ttgataagtt
    52261 aagcccatga tcctactcca aaataaatcg ttccgctaca gtatctccca aaaagagacc
    52321 tctctttgtc atgcgaacgt ggtcaccctc aatctgcatg aggccttgtt gaaccaaatc
    52381 tctgacaatt tctccataaa gtccagcaaa agactgtcca aatttttcct caaatcgcgc
    52441 catggaaacc ccggatttct tgcggagtcc caagaacatt tcttcttcca tttgctcctt
    52501 ttgactcagg tgatcttctg taatacaagc attgccttcc tcaaccgcac tgagataatg
    52561 acgaatggga ccatgatttt tatagcgtac tccattgaca taaccagatg cccctgcacc
    52621 aataccatag tattcagcat tgtcccagta catgagattg tgacgacttt caaagccggg
    52681 tttggagaaa ttagaaatct cataatgctc aaaacccgct cgctccagct ctgcaatgat
    52741 gtactcaaac atctccgctt ctagttcctc cttaggcaga ggcaatttcc cacgtcgcat
    52801 ccgattcata aagaccgtat ggttttctaa aatcaaacta tacaaactca tgtggggaat
    52861 atccagtcca atggctttag ccacattttc ctttacttgc tccatggtct gaccaggcag
    52921 agcataaatc aaatcaatgg agatgttgtc aaaaccagcc agtttcaggc gatcgatatt
    52981 ttcataaata tccttctcca aatgactgcg cccaatcttt ttcaacatct tatcatcaaa
    53041 ggtctggaca cctagcgaaa cacgattgac agccgaattt ttcaaaacag ctatcttatc
    53101 cgcatccaaa tcgcctggat tggcttcaat ggtcaactct tctaagacag acaagtccaa
    53161 gtttttagtc aagccattca gtaaaacctc cagttgcgga gccgacaggg ctgtcggtgt
    53221 tccaccaccg atataaaggg ttgacaactt ttcaatatca taagaacgaa actcttccag
    53281 cagatgctct aaatagctgt cgactggctg atttttgatg aagacctttg aaaaatcaca
    53341 ataataacaa atctgggtac aaaatgggat gtgcacatag gctgacgttg gttttttctg
    53401 catagtaatt attataccac aaagactaga ttccagataa aaatcaccat ccccagatac
    53461 atagtccgtc cggagatggt gatggtttat tcttctgtta tatcaatcac aatctcttct
    53521 gagtcatcaa gagcttcggc tttttcttgc cattgctcct tgagattatt taattgattt
    53581 tttgatgctt ctgtcgcttg aaaagcatag gatttagctt gagcaagtat actgtccaca
    53641 gtgatttcac ctgactcaac ctgttctttt gttttcagaa caaaatctgt agcctgctcc
    53701 ttaacttctg tcagtttttc acagacttgc tccttggcat actccggatc ttctctcaaa
    53761 tcatctagaa aatcttgagc ctgactgcaa acttgtttgc ccttatcact tgttaaaaac
    53821 aaggcaagag ctgcacctga aacggttcct aaaaggattg aggataattt acccataagg
    53881 attctccttt tttatttttt gaaaaattta cttgcaagac gaagagctga cagacttgca
    53941 ccagtcttga gtgtttttga accagctgat gaagctttct tgctcaagac acgcgcatgg
    54001 tcattgaggt ctgaaacaga tagagataaa tctgcaacag cactgaagag tggatcaatc
    54061 gtagccacct tgacattgat atcatctgcc aagacattga ccttagccaa caactcattg
    54121 gtgtgatgca aggtcacatc cacatctgaa gtcaaggttt taatcgtctt ttctgtttca
    54181 tcgatgacac gaccaagctt ttgtacagta atgatcagat agaccaaaaa gacaatcaaa
    54241 gctagggcaa caagaatata tgcaacttct aacatttagt tttcctcctc tgtaatatag
    54301 taaggggcct tctttcgatt ttgataaata acgatcatta taccgagacc gataaggaca
    54361 actgacagcc attgggacac tcgaaggccg aagaacatga gactatctgt tcgcatacct
    54421 tcgatgacca tacgaccgaa accataccaa atcaagtaaa aggccgtgat atgacctcgt
    54481 ctgagactct tccatttccg tctaaaaatc agaatcaagg caaagccaag cagattccat
    54541 agagactcat aaaggaaagt cggttgacgg tagctcccct caatatacat ctggtcacgg
    54601 ataaagccag gtagataatc cagattatcc actgttgcac cataagcttc ttggttaaag
    54661 aaattacccc aacgccccaa actttgagca atcataacgc taggcgccgc aatatctaga
    54721 aaatcccaag tattgatgag tttacggtca gcaaagatat agagcacaag agccccagtt
    54781 atcaaaccac cgtaaatggc caaaccacca ttccaaatgg caaaaatctc tcctaaattc
    54841 tgactatagt aatcaaatcg gaaaataaca tagtagagac gagctcctaa aatagccaag
    54901 ggaaaggcta ctaagataaa atctaaaata tcgtctggta tgatcttctt tctaggtgct
    54961 tctttcatgg tcaaataaac cgcaagaatc aagcctgtca caatacataa ggcataccaa
    55021 cgaatggcta ggggtcctag ttgaatagca attggatcaa gcattttgca cctcatttcg
    55081 agcgatgaga cttgtcagtc gttcgtcgaa caaacgggtc gcatcaaagc ccatttcctt
    55141 ggcacgataa ttcatggcag ctgcctcaat cacaacagag atattacgac ctgttttaac
    55201 tggaatacga atacgaggaa tggctacgcc agaaacttca agttcctctg cattgtttcc
    55261 aagacgatca aaggtcttat gcgtatcgta attttccaaa tagacagcaa gctgaacctg
    55321 tgaagaatcc ttgacagcac tcgcaccgta gagactcata acatcgataa taccaacccc
    55381 acgaatttca atcaagtgtt tcaaaatttc agctggttca ccccagagag taatctcatc
    55441 cttggcaaag atatcgacac ggtcatctgc taccaaacgg tgaccacgtt tgacaagctc
    55501 aagacctgtc tcgctcttac caattccact atctccctga atcaagacgc ccatcccata
    55561 aatatccatc aagacaccgt gcacactggt acgttctgcc aaacgagaat ccagatagct
    55621 agataactct ccagataaac gactggtagc tgcacggctg gttaaaatag caatcttaca
    55681 ttctctagca gcctttaaca tctcctctgg aaccaccaaa ccacgggcaa caatgactgc
    55741 tggtgtctca gatagaaaca tttttttcaa aacttcataa cggctgttgg aaggcatgct
    55801 gatcagataa gaccactcct tcatccccaa aagttgaatc cgctctggtg tgtagtagtc
    55861 aaaatagcct gtcatttcaa gaccaggtcg cgtaatatcc gctgtattga tttccttttc
    55921 aagcaactct ggttcaccat agacaatatc tagtctaagc ttttcaatca cttcttttac
    55981 taaaaccgac atcatttcct ccttcaaatg agttcttctc tctattatat caaattgtag
    56041 gaggaagttt cagatttttg caggctttgg agtatttatt taaaagaaaa aggactagat
    56101 ttctctagcc tttcattcca attagaattt tttacgttta cgagctactt ctgatttacg
    56161 tttacgtttt acagaaggtt tttcatagaa ttcacgtttg cgtgtttctt gaagagtacc
    56221 agctttagta accgcacgtt tgaaacggcg aagtgcgtcg tcaagagatt cattcttacg
    56281 tactactgtt ttagacattt ttttcactcc cttcaagttc gatatctatt tcattctaca
    56341 cgtaaaagga ataattgtca agcaaaaatg ctgtttaatt ttgatttttt cttccattta
    56401 tacaagagtt gaaagcgttc aatagaacat tgctttttta tttttcgagt aagctaagcg
    56461 cttcagcatc tgcgatgatg gttacatcag ggtgattttg gaggctactt gcaggtaggt
    56521 tctcagtcac tgggccagat actgttccgg caatggcttc tgctttcgac tcaccgtaag
    56581 caaaaagaat aatagacttg gcatccaaaa tgtttttaat ccccattgaa atagcttggg
    56641 ttgggacgtc ttcaatcttg gcaaagaagc gtgcattggc ttcgatagta gactggtcaa
    56701 gttctactag atgcgtttga ctgtcaaatg gagtaccagg ctcattaaag ccgatatgcc
    56761 cattgcgacc gattcccaag atttggaggt caactggatg gtcagccaaa atttggttgt
    56821 agcgttcaac ttcagcttca gcattgtcct taacaccacg aggcaagaaa ctttctttaa
    56881 atggtttttg gttgaacaag ttttcttgca tgaagtaacg ataagactgt ggattgtccc
    56941 catcaaggcc cacatactca tcaaggttga cactggttag atttgaaaaa tcaaggtcac
    57001 tctcaacaat ttccttgtaa aattcaagtg ggctacttcc tgtcgcaagt cctagagttt
    57061 gagctccatt agccaatttt tccttcaaaa tctcaaaagc aacttttcca ccttgaactt
    57121 ggttttcaac tttaataact ttcatctttt catcctccat ttctgtctat atttattata
    57181 tggtatagac caatttttgt caagtgaaaa cgatttaatt tctaaaaaaa gagcgtccaa
    57241 acttgaaacg tgttataatg gataggatta gaacttagaa agaatgaaca gatatatgaa
    57301 tacagctgat tttgatttcc acttgccaga ggaattgatt gcccaaacgc cccttgaaaa
    57361 acgtgatgcc tccaaactcc tcatcgtcaa ccgtgagaca ggagaaatgc aagataaaca
    57421 cttccactct attattaata tgctggaacc tggtgatgcc cttgtcatga acgacacccg
    57481 agttctccct gcccgcctct atggtcaaaa agtggagaca ggaggtcatg tggaacttct
    57541 cctccttaag aacactagtg gagacgagtg ggaagttctg gctaaacctg ccaaacgcct
    57601 caaggtcggt actcgtatca gctttggtga tggccgcctc agcgctgtcg ttacagaaga
    57661 attgacccac gggggacgca ttgtccgctt tgaataccaa ggaattttcc tagaagtctt
    57721 ggaaagtctg ggagaaatgc ctctgccacc ttatatccac gaaaaattag atgaccgtga
    57781 acgttatcaa accgtctacg ccaaggaaag cggctctgct gcagcaccga ctgctggtct
    57841 tcacttcacc aaagaactgc tggcagaaat ccaagctaag ggtgttcatc tagtctatct
    57901 gactctccat gtcggactcg gaacctttag acctgtttct gtggataatc tggacgaaca
    57961 cgaaatgcat tcagagttct atcaactttc tgaggaagct gctgccaccc ttcgctctgt
    58021 caaagaaaat ggtggtcgcg tcatcgctgt cggaaccact tctatccgca ccttggaaac
    58081 tattggttcc aagtttgatg ggcaaatcca agcagattct ggttggacca atatctttat
    58141 caaacctggg tatgagtgga aggtcgtgga tgccttctca accaacttcc atctgccaaa
    58201 atcaactctg gtcatgttgg tttctgcctt tgcaggccgt gaattagtct tagatgccta
    58261 ccaccatgcc atccaagaac actaccgctt cttcagtttt ggtgactcca tgtttattta
    58321 ttgagaaaga atttctctaa atcttctaat accaataaat cgctaagata ttatttcaaa
    58381 gaacatctac aattgaaact ctagctagct gtagaagacg cctagtacat tgaaattaaa
    58441 atgcttcccc ctagcttcga aaatattgcc atagattgcg ttgactctcc aaattgattc
    58501 atctatattt tatttcagct tcctatattt tcttcgctgt ttgtaaatca aaatgcaaga
    58561 cacatgagta gcaccatatt tgttactctt atctgtcctc tcaagagact attatgagtt
    58621 atttcagaat cattcactac tttgaccctg actctcctta gtctcaaaat caaagactta
    58681 tactcttcaa aaatctcttc aaactgcgtc aacgtcacct tggattatat atgtgactga
    58741 cttcgtcagt tctatctaca acctcaaagc agtactttga gcaacctgcg actagttttc
    58801 tagtttgctc tttgattttc attgagtatt aaacaaaaag tgaacaaatc tgaattctaa
    58861 tgtacagaag actaggcttg ttcacttttt tatagtcgct ataagatgac cttatctata
    58921 gctttttata tataattata tataattata tattcagaca tactattatc aattttgtcg
    58981 cagggaggaa tctgttaacg cacccattca ccattatcat tgactctata gccatctata
    59041 cttgtattga ccgctaactc acccgatgca tttacataat accatttacc accaacttgg
    59101 aaccattgat tgactttcat agaaccgttg ctgttgaggt agtaccatga accattaact
    59161 tgtacccaac ctgttgccat ggaaccatca gtattataaa aataccacat accattttct
    59221 tgtttccagt ctgttgttgg agcaactgct ttagctggtt ctactgctac atctgttcct
    59281 tggttagatg taacagatac aggatacgaa ggaatagatg attgctcagg aacaacaact
    59341 ttttcaggtt ctctcgtccc tctccttata cgtcttttta ccatctcttt agtaatttga
    59401 cgagaagtag tttcttcaat tgttccatca cgttcatcta cagtatagat tgtagtaaga
    59461 gtaatttacc aatttctcct acttcttcta cttcttgact tttatcaaga gttgggtcat
    59521 cgagatattc tgtttcgatt ggaatttctt ggacaagaac ttggggcttg gttccttttt
    59581 taacaactct tgtttgagag tcttcttttt gacttaaagt actctcagtt acttgtccac
    59641 tctttccatc tacatcataa gttatcgttg taactgtttt cccattcttt cctagagtaa
    59701 tctcttgctc ctgtcctgca gaaaggtcat tgtctgcttc atatttagta gcacatggaa
    59761 caagaacttc ttcaaccttg cttttagctg gaactttgat aactgtatcc gtggcttgtt
    59821 ttctatcaac agtaacctgt tcggtaacat gaccagtctc tggattaaca tcgtaggtcc
    59881 ttgtcgtagt tacatagcca tcctctccat caattgtaac aggattttca ctacggtctt
    59941 ttgtttcatc tttttcataa cgaattcgcg tacttgaaat tttcttggtt actaccttag
    60001 gtttagtcgc tacttttaca ataatacccc cattgtcagc gtcatcatac tctattccct
    60061 cttctttatc tctagtatca tctctgacat attgaatccc atcagcagca tgaacaaaac
    60121 ttgtattcag attcctccta aaaataaagt tagcccgatt accgcagaac caaaaatctt
    60181 tccgagttta cgtaatgcat agcgcttatt agtattagat tttgccatta catcctactt
    60241 ctagtatagc atcttttcta tcaaacgtta aacaatatac tttatatata aaatagactt
    60301 agaatgatat attgattatt gaactaacac tttaactata tcgtaatcaa tctcatatat
    60361 aaaggattgc agacatctta tctaaataca tgctaatata tttagataca aacattccaa
    60421 cttgataatt ttcactcatc tttcatcatt ccttatacaa ctatgcagta taaatagaat
    60481 agttttctca tcagaatgag actattttaa tattagataa tttgatagaa aaaacatgaa
    60541 taaaattggt tgaatttaat tccctaactc gatagaggat tctattttaa atttaacaac
    60601 agctaggatt acactataaa aagtacatta ccacctgttc ggctggagaa tctagtcgat
    60661 tagctccctc ttagttacaa gcttaaagcg attttttaac taatactaaa ccagattaaa
    60721 gaaggaacta gaacatctgt cttgtactaa tcaatatgct attttaaagt ttcaaataaa
    60781 cttggaatgc taattattat atttacaata aatagttgac ttcgatagaa acagaaaata
    60841 gaattcaaca ttcttcccta cttataccat aataaataag atccgcaaga tagccttttc
    60901 tctctacacc attaacaatg gtttgtagat aggacattcc agccttttcc atgacacgac
    60961 ctgaagctgg gttgagactg gcataacgtg ctctgacctt ttgaaaacct gcttgagtaa
    61021 aacaaaagtc caagatagct ttcaaagtct ctgtcatcat accatttccc cagtaagcct
    61081 tgcctaacac atagccaatt tcacagctta aatcagcctc gtctatctta acgatgctga
    61141 tatctcctat cacttgctct gggttttctt ttagacaaat ggcccattta taatagttga
    61201 gattagtata ggaagcaacc caattgcgaa tcgagtttcg agtgatttcg atatcaggat
    61261 ggggatccca ggtaacatag gtcagattct cagcagatga agcccaattt tgaaacatgg
    61321 cttctgcatc actctccaca aatcttctta aaatcaaacg ttctgtctgt aatatttgcg
    61381 taccgataga tttcatgatg ctacctcact tccttatttc tatgctcgta gtaaaaaggc
    61441 tcaactcagt aacagctaga aaacgagttt gtcttctaat ttcttgacgc agtcgctgcc
    61501 tggtttgaaa tgcgctctag caagcttttt caaacctagt catcgttgca ggggtaagac
    61561 gatgaaatcg aactcttcga gttaccgaat ctgcctcatt ttcttatttc taaactcggg
    61621 gttcaagatc ccccagacct tctctcactt tcttatttca agatgagagg ctgaaaacct
    61681 ccagtggagg tttttcttgc tttttaattt cagggcaaga agctaaaaag gtccccggac
    61741 cttcttcgct ttctcatttc taggctcagg gtaaaaacct ccaatggagg tttttactcc
    61801 caaaagtcat caaatacagt gatgggtaag tggcgtttgt gttggccttt gtgccaccag
    61861 ttttcaatgg tcgcttgagc ttctgggctg attgttttgc cttctaggta gtcgtcaatc
    61921 tctgcgtagg tgactccaag tgcgacttcg tcagctaggc ctggtttatc ttcttctagg
    61981 tctgccgttg ggattttttc ataaagggct ggctctgcgc caagtttctg caagagctgt
    62041 tttccttggc gtttattgag gcggtaaaga gggagaatat ccgcaccgcc gtcaccaaac
    62101 ttggtaaaga aacctgtgat attttccgcg gcgtggtctg ttccaatgac cgctccgcta
    62161 tgggaaccag caagggcata ctgagcaatc atacggcaac gtgccttgat attccccttg
    62221 ttgaagtctg aaacaggact acctgtcgct tcaactgcag ctgtcatggc atcagctgat
    62281 tccttgatat tcacaaccaa gctgacatct ggctggatga aggctagggc tttttgagca
    62341 tctgcttcat cagcttgcac tccgtatggc aggcggacag cgataaattt gtagctgtcg
    62401 tctcccgttt cagctcgcag ttcttccata gctaattgcg ccaaacgccc tgccaaggtt
    62461 gagtcttgtc ccccagaaat ccctagtaca aaggttttta ggaagggatg ttttttcaga
    62521 tatcttttta agaaatcaat agaacgacgg atttcttcct gggcatcaat cactggtttg
    62581 acacccagct cttggataat cgtttcttgc aaactcattc ttcttctcct tcaccaaggg
    62641 cttccttgcg catcttatca atcaagtcca tcttatcttg ccatacatca cgcgccaaat
    62701 ccactggata gtgctgcgga ttgagcacac gcttatactc atcccacaac ttgtcaaatt
    62761 ccttacgggc ataatcctga atgtcagtca aactaggcaa gttgtaaact aatattcctt
    62821 ctttgaagat atccaccaag agaggaacgg catcaaaatt acgaaccgtc ttcttgatgt
    62881 atgtataggt cggatggaac atcttgattt ctgtcatgtc gctaatatcc acaccatcat
    62941 aagtgatata gtcgccttct gacttgcctt tttcacgact ggtaatgcgc cacacctgct
    63001 tcttacctgg cgtagagact ttttccgcat tattagacag cttaatcgta ttgcgcatct
    63061 gaccagtttc atcttcgatt gcaacaatct tgtaaactgc accaagagct ggctggtcat
    63121 aagctgtaat cagcttggta cccacgcccc agacatcaat cttggccttt tgcatcttga
    63181 gattgaggat ggtattttca tctagatcat tagaagcata aatcttagcc tctgtaaatc
    63241 cagcctcatc cagttgctga cggactttct tagaaatgta ggcaatatcc ccagagtcaa
    63301 tccgcacacc cataaagtta atctgatcac ccagctcacg cgccacctga atggcagctg
    63361 gtacaccgat gcgaagggtg tcataggtat ccacaagaaa gacacaattt ttgtgggtcg
    63421 cagcgtaagc cttgaaagct tcatagtcat tgccataaac ctgtaccaag gcatgggcat
    63481 gggttcccaa aacaggaatg tcaaagagct tacccgcacg cacgttgctg gttccattgg
    63541 cgccaccaat cacagctgcg cgtgttcccc agatggccgc atccatttct tgagcccgac
    63601 gtgtcccaaa ctccatcaag ggttcatctt cgataaccga acgaatacga gctgccttcg
    63661 tcgccaccaa ggtctggtag ttgacgatgt tcaaaagagc cgtttcgacc aactgacatt
    63721 gggctagagg tccttccacc tgcacaatcg gttcattagc aaaaaccaaa tccccttctt
    63781 gggcagaacg aacggtcaac tccaacttga aattgcgaag gtaatccaag aacgccccat
    63841 gataaccaag cgactccaaa taggctatat cactatctga aaaacgcaag tcttcaagat
    63901 agttcacaat tctttccaaa cctgcaaaaa ccgcatagcc gttcttaaaa ggctgttggc
    63961 ggaaatacac ctcaaagacc gccttcttat tgtgaatccc ttggtcaaag taaacctgca
    64021 tcatgttgat ctggtacaag tccgtgtgca atgtcaaact atcatctgga tacatacttt
    64081 tcctacttcc ttagctagaa acccatgaaa attttcaaga actttcatgt attccaataa
    64141 attagtacta ttatatcaca ttttagctgg attgagaaaa gagtaacaag ctattctcca
    64201 ctctccaatt catccatatc ttgttcaaat tttttctgag cccattcgcc atagctctta
    64261 agaccaagat tgccaataaa gacccacgga aggtaaatga cataagtaat gacccaagca
    64321 gacaggtatt taaaattcaa aggattgtgc tgataaattt ctatgttgaa ttgataattc
    64381 tgcaacatca aaagagccgt aatagccaag gttaggaaaa aacaacccaa aatcgtaaaa
    64441 tgaaaacgac tatagtaggt cactcccaga taacgggcac ggttaaaaaa gtaaaatgtc
    64501 cctatgatga taacgattag cagcatatta gaattaaaaa ggcttggtgc taatactgaa
    64561 atgatataag ataggagcga caaagcgatg cagatataga aactttcaga gcccgcttta
    64621 ttgatcagtt gttcttctct ttcgtctagt aattgataat aataaaatct atttttcatc
    64681 ttcttcctcc caaaatagtt ggtctagggt tttccctaaa catctgcaaa tagactggca
    64741 gagcgagaga ctgggattgt attttcccgc ctctatcaaa ccaatagtct ggcgtgtcac
    64801 cccgacagcc tctgccagtt gaccttgtgt taaatcacgc tctacccgag ctaattttaa
    64861 ttttaaattt ttagccacct tcgtcctcct tatagtttta atactcatct actctttaaa
    64921 aatccaaact aacacaagct gtcagctatt tattataacc ccattaattt gcactccagt
    64981 attatcttca gccgaaaatc agtattttag gttgtttgaa ataaacttcc tagtttactc
    65041 ttttattttt atttttattt agcattagct ttagtaggat cttttaaacg agtttttatt
    65101 gcttatattt cttgtttagt ttagttggtt tcatatcact attatataat gcttttggaa
    65161 atgagcctag tataagtcaa aaacgtgttg aatagtgaaa gcaggagcat accaatatga
    65221 ctgatttttt actgtatttt aggtatgcaa aataatacta aatgaaacta aaatgaatac
    65281 ttcttgcttt tcttgagagt gaaaaagtac aataaaatga ttgtagtgat tgccacaaga
    65341 tactgactaa tagacatcgt atttgaagcc acaaatacag gtaaagaata aaaaggaaga
    65401 agttcaattg ctttgataaa caaatcatta ctagtattca tcatcgtatt taatatatta
    65461 gggataaaga gtagtaaagc tactaaaata ccaagccact tttcaatttg tataaataga
    65521 aaatgtaaga taatagaaaa taaaacagga ctaacaaaat tgtattgact acaatagcta
    65581 ctataaaatc taatcctaaa tcacctggaa tacccaattt acttactatg actagtaaca
    65641 caatgccatt caaagcataa ataatggaag ctgagatggc atatagaaaa ttagacaaga
    65701 cgtaaatcat ccgattcttc tgttgattat aaaacaaact taccgtattg tgggaaaaat
    65761 ctctactaat gactcgatta gcatgtataa cagccattaa cataccgagc atagcataaa
    65821 agtttgaaat atgcttaata ccaagcgatg tcccttaagt ctttagaata aagaatgtaa
    65881 gcaatatcgg cggtataaac gagataagca aactgagata tattacgcct gatgaatata
    65941 aatttcttat attttcctta agaaaattca atttatttaa tttcatgatt ataaccttcc
    66001 tttattttga acgatttagg taaatatctt taagcgtctc ttttttagtt tcaaaatcaa
    66061 ctactttaat agagttttcg ttaaaaaatt taaaaagctc actactttga atattcccag
    66121 acatagtaat tctcaatccc tcttcctgaa caatatcccc aaattcttgt ttggtaatga
    66181 aaatgtctct atctgtagct gatgaaaaag ctatctcaaa caagaaatta tgactatctt
    66241 ttcctacttt ttgaaatgtc aaaagcccgt tctccaagaa aagaactctc tcacaaattt
    66301 cttcaatgtc ttctaattta tgactcgata ttaaaattcc cacgttttca tttaaagcta
    66361 atttttttag aaccgctaaa actatttgtg atgattcaat atctaaacca ttagtcggtt
    66421 catctaaaat caatatatca ggttccgtaa cgagagttag aagcaaagct aatttttgtt
    66481 ttgtacccaa agaataggtc tttacttttt tattaataga ctgagtcaaa tctaactctt
    66541 ggatcaaact tctaaatctt tcttgattgt agtcaacacc atataaattt gacaaatatt
    66601 ttaaattctc taaacctgtt ttagataaaa ataattttgg ttcttcgatt aaatacccaa
    66661 cattatcact gcttataata ttacctgaag tcggttgatt attttgaaca agaattttca
    66721 tcaacgtact cttaccaact ccatttctcc ctactagacc aacaatttca cccttgttaa
    66781 gtgcaaaatt tatatctttg agaatgattg aatgaccata atgcttactt acatttttat
    66841 tcctacatta atattcatgg tttactcttt gattcttatt gagtttaaaa agttgcgcct
    66901 ctttttaaca atattatatc atatatctaa cttgatgcaa tatataaatg tcattttgta
    66961 aaattttatt aacaaaaaac tctctacaac aaaataatag agagttttct gcttattaat
    67021 ttttttcaaa atatctaaga catcgcttct ttgtttaatt tgataggctt tgatacctaa
    67081 gctccgactt tatcacttaa aaaataaaaa agacagctaa tctcttgcgc atcaagggat
    67141 ttcgccattc tttaatctcg tttaagtgtt gtatatggag ctttgcataa ttttttaaaa
    67201 ctaaacaact acattaagca cgaactgtga cgctggttcc atcttcctta taaagattga
    67261 taagcccctc tttaagagct cgaaccatgt ctcctgattg aacgggttgt gggactttaa
    67321 tagtcaatag ttccattgga tttggagcgc ggtcgatttt attgcctttg gcatcatgca
    67381 aatcttcaat ataggtttca aaatgacgga aacctggacc ataaaactca acttggtccc
    67441 cttcgttaat gacgtttcgt tgacgaatag ttgctgtttg tgccgcatca tcataagaaa
    67501 ccacttcagc gacaaacttg tactcaggga ttttacgacg agcaccaaac aactgctcat
    67561 tttcagatgg tgtaccatag taaaatcctg tagccagttc acgttgggca accttccaca
    67621 tctcgtccac caagtcttgt ttgatagctt caaacttttc aggactttca agataggcat
    67681 ccacaaccgc cttgtagcag ttggttactg ttaatacata gtgaatagac tccatacgtc
    67741 cttcgatttt tagactgtcc acaccatttt caatcatatc tggaatgtgg tcaatcatag
    67801 acatgtcaac ggctgacatt gaaaattctt ctggaatctc accctgcaaa ctcttacgtt
    67861 ctttcccaaa tggcatatcg taaaggtcgt atttccaacg gcatgactga gaacatccac
    67921 cacggttggc atcacgcata ctctagacgc aattctaatc ttttagactt tgcataataa
    67981 ctgttaaaca gttgaaaatt aacccagttt taacaagtag tcaaaatacc agataaagga
    68041 aaaaaagtct ttaaaatctt aaaaacgcat agtatcaggt attgaacaat cttgatatta
    68101 tgcgttttat tgtgggaaga tttacttcat tttctcttgg aattgagttt tctcctactt
    68161 caaaactaga tgatttgcta tttaaaatag cgttccttat gattttggca acctggatta
    68221 aagcgagaaa aacaaaaggg gcaacttaag ctttctttat attgcttata tgttagtagt
    68281 tttagacaaa caccacataa aataggctta tcctgtatca aagataaggg atacggctca
    68341 aaagggtgat tttctaatga atcatgacac cgataacaag catagtactt tttacaaaca
    68401 tagcattgta aagcaataat atccagcttg ctatggtaat gaatgcatct tgtttgctta
    68461 tccactaaga aaccctgtgc ctctatcatt tccttttcct ttcttaagct cgaactgtga
    68521 cgctggttcc atcttcctta taaagattga tgagtccttc ttttaatgca cgaaccatgt
    68581 ctccagcttg aacaggttga ggcaccttaa tagtcaatag ttccattgga tttggagcgc
    68641 ggtcgatttt attgcctttg gcatcatgca aatcttcaat ataggtttca aaatgacgga
    68701 aacctggacc ataaaactca acttggtccc cttcgttaat gacgtttcgt tgacgaatag
    68761 ttgctgtttg tgtcgcatca tcataagaaa ccacttcagc gacaaacttg tactcaggaa
    68821 ttttacgacg agcaccaaac aactgctcat tttcagatgg tgtaccatag taaaatcctg
    68881 tagccagttc acgttgggca accttccaca tctcgtccac taagttttgt ttgatggctt
    68941 caaacttttc agaactttca agataggcat ccacagccgc cttgtagcag ttggttactg
    69001 ttgatacgta gtgaatagac ttcatacgtc cttcgatttt tagactgtcc acaccatttt
    69061 caatcatatc tggaatgtgg tcaatcatag acatatcaac ggctgacatt gaaaattctt
    69121 ctagaatctc acccttcaaa ctcttacgtt ctttcccaaa tggcatatcg taaaggtcgt
    69181 atttccaacg gcatgactga gaacacccac cacggttggc atcacgcata ctcatgtggt
    69241 ttgaaagagt acaacgtcca gagtatgaaa tacacatagc tccatggaca aaggcttcaa
    69301 tttcaacatc tgtacgtttg cggatttcag ctaattcttt cattgaaacc tcacgtgcta
    69361 aaacgacacg agtcaagcct agctctttcc agaactcaag ggtttcatag ttagtggcac
    69421 tggcttgggt agaaaggtgg atttcaaggc ctggtgcttc agtcgctgca atcataatca
    69481 aggctgggtc agatacgata actgctgcaa tcccgatatc acgcagttta cgaaaccact
    69541 caccagcacc agcttcattt ccttcgtgca taaccatatt agccgctaca tagaccttgg
    69601 caccatactt ggccgcaaac tgcacgcctt cttccatctg ttcgaaagta aagtttcccg
    69661 cacggctacg aagaccatag gcctgaccac cgataaagac agcatctgct ccatactgaa
    69721 cagctacctt tagcttctct aaagtccctg caggtgataa aacctcagga cgttttaatg
    69781 tttttgtcat gatttctcct atttgcaata taaaagtttg acatttttcc ttctcatttt
    69841 atagtaaata aaggataaaa tcaagcctag acggattgtt ttgacaattc taatctttta
    69901 gactttgcat aataactatt aaacagtcga aaattacccc agttttaaca agtagtcaaa
    69961 aagtctaaaa aagtaaaaac cagtatccca agatactgac tcgtaaaaat atataaatta
    70021 gtccttagat gactactccc actctgttgc tcctataatg gaaaaggatt gatacagtct
    70081 agaatatcgc ttttttattt attattctga tataaaactg ttagaattga ttttttgttt
    70141 tatacccaaa tatgaataga gacgtagcta ataagttgaa taacatattt ggaaaaatga
    70201 gaaatagcaa tattactaga acttttagaa acaatcaata tttaaaaaga aaaaagctca
    70261 aagaatttat taaaccatgt tataatagat atagctataa ttttatttat aacaagagga
    70321 tagaaatgac cgaattagaa agaaaaaatc gaaaaattag ctaagaaata ttctgataac
    70381 ttaaacatca aagttcaaga gagagttcgt gaaatggcaa atgataataa gagccattat
    70441 ttgatataca gagttttagg tatttcattt gaagaaggag aaaatatcga tttgtatcaa
    70501 aataaaggtc gttttttata caaatatgct ggttcatttt tagaagaagc tgcagtacta
    70561 tcctttaacg aaaaatttgg tacagaaaat acttaaaaag ttaacattcc taattctgaa
    70621 aatacaaaac ctaagacttt tgaaattgat tgtttagtcg gagaaaaaca cgcatacgaa
    70681 ataaaatggt gggatgcaac tacagatgga gaccatataa ctaaagaaca cactagaata
    70741 aaagttattc ataacaaagg atatatacca attcggttaa tgttctacta tccaaataga
    70801 actcaagcta taaaaattca gcaaacttta gaaacattgt ataacggtat tggagggaaa
    70861 tattattatg gagattctgc ctgggaacat ttaagagcag tgaccggtat tgatttactt
    70921 agtattctaa cagatattgc aaataaaaaa acaggggtaa aatcaaaatg acagtattaa
    70981 aaggagataa cttagaaata ttaaaaacta ttgaatcctc aagtattgat ttaatctata
    71041 tggaccctcc tttctttaca cagaaaaccc aaaaattatc taataacaaa aatattatgt
    71101 attcattcga agatacgtgg acttcgattg aggattacaa agaatttttg tctgtaagat
    71161 tagaagaatg caaaagagtg ctaaaaaata gtggcagtat tttcgttcat tgtgataaaa
    71221 ttgcaaatca tcatattaga ttaattttag ataatatctt tggagcagat atgtttcaaa
    71281 gcgaaattat atggaactat aaacggtggt ctaattcaaa aaagggatta ttgaacaatc
    71341 atcaaaacat ttacttttat tcaaagtcaa aagattttaa atttaataca atttttacag
    71401 agtattcttc tactacaaat atcgaccaaa tactagtaga acgaaaacga aatggaaact
    71461 ctaaaactat atataaagtt gataataatg gtaactatat tctagcaaaa gagaaaaatg
    71521 gagttcccct ttcagatgtt tggaatatac catttcttaa tccaaaagct aaagaaagag
    71581 taggttatcc tacacaaaaa cctattctgt tattagaaca aattataaag attgctactg
    71641 ataaaaatga tatagtttta gacccgttct gtggaagtgg aactacttta gtagcctcca
    71701 agattttgaa tagaaattat atggggattg atttatctga ggaagctatc aatataactc
    71761 agcaacgtct ggaaaatgtt ataaaaacaa gttcaaattt attgaataaa ggaatcgaag
    71821 catatagaac caaaactgag gaagaggaaa acattcttaa attattacag gcaaaaattg
    71881 ttcaaagaaa taaaggaatt gatggttttt tacctaaaca ttttcaaaaa aaaccgatac
    71941 ctataaaaat tcaaaaaaat aatgaatgtc tgaatgagag tatctcttta ttacagaatg
    72001 ctataaactc caaaaaactt gattttggag tagttataaa aactcattca gataatttat
    72061 tatttgattt tgatacgatt cctgaaaata taatagtagt tgaccatttt gaacttacaa
    72121 tcgaaaaatg gttaagtaaa agtcaacagt tactatagtt tgcaaattat ttacagaaag
    72181 aacaaaaaat gctctgaaac actgatttca aggcattttt tgttagttta aaattactcc
    72241 cattcttctt ttccaaacgt acaatatatc caaaaccatt caaaatacta gattctattt
    72301 tttataatat cactaaatcc acctaattat aggacgtttt cagattttta gtcccgtccc
    72361 agtcccagta ccggagaaat attgttttaa tataatatct ctttttgtct tctaagctct
    72421 taaaagcaaa agaacaagta aagagtcaag acaaggataa aaagtccata ttagggcaaa
    72481 taaaaagctt taagacagat gacaaatcta agtcaaataa gaaagaccat agcaaaggtg
    72541 cagagagata aatattggcg gtcttcggac tgcctttatt tttttatcca tttttcaaat
    72601 caaatttatt cagactatat atgcacatat acacttaaat tcatataaaa acatggcttg
    72661 taaaaaatta ctttaatcac aataatcgca tttaaaattg tgatgtttgc aagctaaatt
    72721 acggacttca cttggaagtt ttcccttgta tcttttataa tagatagaaa atttgctggc
    72781 agatgaatat ccaacagatt ctgctatctc ttttataggt agttcagtgt ttaaaagaag
    72841 agtttcagct acattcattc tttttctttg agtgtactct gtaatgcttt gacaatattt
    72901 ttccttaaat aaatttttta atttagtacc actcatttta gatatttttt caagcgtgcc
    72961 ttgatttaca ttcgttgcaa aatgatcatc taagaatctt gctacatctt caagtgcttt
    73021 atcatcatca atttcaattt tatatttttt tctatttaag tatgtgtcaa ttactatact
    73081 tatccattca tttgcctttg ctttaaagaa aaaatcagcg gcaggagcgt ccatcttaca
    73141 atttaatatt tccattgcca ctctttctaa ggcctttgta agtattattt gattcggttg
    73201 aagcaaggtt gaataaaaag attctggatt aatgttaata gatgctaaat gtttttctat
    73261 tagctctttt ttaaaaccaa tggaaacagc aagataacaa caattctcgt gtaataaaaa
    73321 aacaaaatca tcttttatat tatcaaaatc aaaagtacat aaagagtttg cggtaatagt
    73381 ttgatacgga ttaaactttt ctccgtttgc actgacaatg taacttgaat aaattgaaac
    73441 atagtctgac atactataag tgctattttg aactacttcc tctttgatat aaaaatcatg
    73501 tatatcgata atgaagctgc ctccttcata aaaccaatat aggccttctg cataagttga
    73561 attctctttt ttccaacaaa atgtatgacc tgcacttgaa tacttctcat tgtttttaca
    73621 ttcatctact ttcatataat cttttacaaa atcataatat gacataacac actatccctt
    73681 ttagacaata ttccaattag ccttattaat tcaaaactat tgtattagta attataacag
    73741 atgtataata gaaaagcaat gatagatatt atcaattaag cgaatttata tctaaaaggg
    73801 atattaaaga aaggagatat gcttatgaag atttacaaaa aactatttgc ttatgtccaa
    73861 gataagaaat atcttggggt tttggccata attttttctg ctatatctgc tgtacttaca
    73921 gtatatggat attatttaat ctacaaattt ctagataagt taataattaa ttcaaactta
    73981 tccggtgcag agagtatagc attaaaatct gttattacac taacaagtgg agcgatattt
    74041 tattttgtct caggaatgtt ttcacatatc ttgggattta ggcttgaaac aaatttaaga
    74101 aaaaggggaa tcgatggtct ggaaaaagca agttttaggt tctttgactt aaatccatct
    74161 ggtcaaataa gaaagatcat agatgataat gcagcacaaa ctcatcaggt ggtagctcac
    74221 atgattccag atagctctca ggcaatagtc acacctatac ttgtccttgt acttggcttt
    74281 atagtaagta taagagttgg cataattttg cttgctctta ctataattgg tggcttaatt
    74341 ttaggggcaa tgatgggcga gcaagaattt atgaagatat accaagaatc cctatctaaa
    74401 ctaagtgctg aaactgttga gtacgtgaga ggaatgcaag ttgtaaaaat atttaaagca
    74461 aatgtagagt cttttaaaag cttttataag gcgataaaag attactcaaa gtatgcttat
    74521 gattattccc tatcttgtaa aaggccttat gttttgtatc aatggttatt ttttggactg
    74581 attgcaattt taattattcc tatagtttat tttatgacta gcttagctag cgcagaggtg
    74641 attttacttg agcttatcat gattttattt ttatcaggag ttctctttgt ttcattcatg
    74701 agaatgatgt ggtactccat gtatatttct caaggaaatt atgcagtaga tactttagag
    74761 gcgctttacg aagatatgca aaaagacaaa ttagtgcatg gtaatgtcaa taattttaaa
    74821 aactataata tagaatttga gaatgttagc tttgcttata atgataaagc tatcattgaa
    74881 aatttatcct ttaatttaga agaaggaaag tcctacgcac ttgtcggttc atctggatca
    74941 ggcaaatcaa cagtagcaaa acttatatca ggtttttaca atgttaataa aggaagcata
    75001 aagataggcg ggatagcaat aagtgaatat tctgacgaag ccttaattaa agccatttcc
    75061 tttgtttttc aagattcaaa attattcaag aagagcattt atgataatgt agctttagct
    75121 aataaagatg cgacgaaaga tgacgttatg agagccttaa aattagcagg atgcgattta
    75181 atattagaca aattcccaga aagagaaaat acaatcatag gctcaaaagg tgtttattta
    75241 tccggtggag aaaaacaaag aattgcaatt gctagagcaa ttttaaagga ttccaaaatt
    75301 attattatgg atgaagcatc agcatctatt gacccagata acgagtttga attgcaaaaa
    75361 gcttttaaaa atcttatgaa ggataaaaca gttatcatga ttgcacacag gctatctaca
    75421 attaaagacc ttgatgaaat tattgtcatg gatagtggaa aaattataga aagagggtct
    75481 gacaaagaat taatgtcaaa agatacaagg tataagagcc tgcaagagat gtttaacagt
    75541 gcgaatgaat ggagggtttc aaatgaaaga gttttataaa aaaagatttg ctcttacaga
    75601 tggaggagca agaaatttaa gtaaagcaac actggcttca tttttcgttt attgtataaa
    75661 catgcttcct gccatattac ttatgatttt tgctcaggaa gttttggaaa atatgggcaa
    75721 aagcaatggc ttttatatag tattctcagt tttgactttg atagcaatgt atattttgct
    75781 ttctatcgaa tacgataaat tatataacac aacctatcaa gaaagtgcag atttaagaat
    75841 aaggacagcg gagaatttat caaaattacc tctatcttac ttttctaaac atgacatttc
    75901 cgacatttca caaacaatca tggctgatat tgaaggcata gagcatgcaa tgagccactc
    75961 aataccaaag gtgggcggca tggtactgtt tttcccatta atatctgtaa tgatgctagc
    76021 gggcaatgtc aagatgggtt tagctgtaat tattccatct attttaagct ttatatttat
    76081 acctttatct aaaaaatatc aggttaatgg acagaataga tattatgatg tcttaagaaa
    76141 aaactcagaa agctttcaag aaaatatcga aatgcaaatg gagattaaag catataattt
    76201 atcgaaggat attaaagatg acttatataa aaaaatggaa gatagtgaga gaatacactt
    76261 aaaggcggaa gtaactacaa ttttaacttt gtctatatct tcaatattta gctttatatc
    76321 tcttgctgtt gtgatatttg tcggcgtaaa tctaattatt aataaagaga taaattctct
    76381 ctaccttata ggatatttac tagctgctat gaagataaaa gactctttag atgcatctaa
    76441 agagggcttg atggaaatat tttatttatc gcccaaaata gaaagattaa aagaaattca
    76501 aaatcaagat ttacaagaag gcgatgacta tagcttaaaa aaatttgata ttgatctaaa
    76561 agatgttgag tttgcctaca ataaagacgc aaaagtttta aatggtgtaa gttttaaagc
    76621 taagcaggga gaggtcactg ctttggtagg tgcaagtggc tgcggtaaaa caactatctt
    76681 gaaacttata tcaagacttt atgattatga caagggacaa atcttaatcg atggcaaaga
    76741 tataaaagaa atatcaacag aatctctttt tgataaggtc tctatagttt tccaagatgt
    76801 ggttctcttt aatcaaagcg ttatggaaaa tattagaatc ggtaagcaag atgcaagtga
    76861 cgaagaggtt aaaagagcag caaaacttgc aaattgcaca gattttatag aaaaaatgga
    76921 taaaggtttc gatacagtta ttggtgaaaa cggagctgag ctatcaggag gagaaagaca
    76981 aagattatca atagccagag ccttcttaaa agatgcgccg atattgatct tagatgagat
    77041 aacagcaagc cttgatgtta acaacgagaa aaagattcaa gagtctttaa ataatttagt
    77101 taaagataaa actgttgtaa tcatttcaca tagaatgaaa tccatagaaa atgcagacaa
    77161 gatagtagtt cttcaaaacg gaagagtaga aagcgaaggt aagcatgaag agcttttaca
    77221 aaaatcaaaa atttacaaaa atttaataga aaagacaaaa atggcagaag aatttattta
    77281 ttaggaggac tacaatggat aataaaaaat taaaagtaaa agatttagta agtatcggtg
    77341 tttttggcgt aatttatttt gccttcatgt ttggagttgg tatgatgggc ttgattccaa
    77401 tattgttctt aatatacccg acagtattag ccatagttgc aggaactgtt gttatgttat
    77461 ttatggctaa ggttcaaaag ccatgggcac tatttatatt tggtatgata tcaccacttg
    77521 tgatgtttgc agctggtcat acctacgtag ttgtggtttt atcacttata gtaatgataa
    77581 tagcagaatt aattagaaag attggtaatt ataattcatt taaatacaat atgctttctt
    77641 atgcaatctt cagcacatgg atatgtagct ctttaatgca aatgctttta gcaaaagaaa
    77701 aatatatgga gtggtctttg atgacgatgg gaaaagatta tgttgatgta ttagaaaagt
    77761 taataactta tcctcacatg gctttaatag ccttaggtgc tttcttagga ggaattcttg
    77821 gagcatatat aggcaaggct ctattgaaaa aacacttttc aaatggatta tattgtgtgg
    77881 gatactttac tccttgccta attttatggt gttatctgaa ttaaacccta tagttaagat
    77941 gtttttgagt atacctattg ttattagaat gtttatttta ccatttatgg cagcaagctt
    78001 tatgataaag acctcggatg taggcgcaat aatttcatcg atggataagc ttaagatttc
    78061 aaagaatgta tccataccta ttgcggttat gtttagattc ttcccatctt ttaaggagga
    78121 gaagaaaaac atcaaaatgg ctatgagagt aagagggata aattttaaaa acccagtcaa
    78181 atatcttgaa tatgtttctg tgccactact cattatatca tctaatatat cagatgacat
    78241 tgcaaaagcg gcagaaacaa aggcaataga aaatccaatt gccaagacca gatacattcg
    78301 cgtaaagata cagctaattg attttgttta tgttttagcg gttgctggac ttattgtggg
    78361 aggcttaata tggttgaaat aaaaaattta agtcttgatt atggtgaaga gcatatatta
    78421 gatgatatat cactatccat agccgaggga gagtgcgtgc tatttacagg aaaaagtgga
    78481 agtggtaagt catctttaat aaattcaatc aatggactag ctgtaaggta tgataacgca
    78541 aagacaaagg gcgaaataat tattgatggt aagaatataa aaaatttgga actttatcaa
    78601 atctcaatgc ttgtttcaac tgtttttcaa aatcctaaga catatttttt taatgtcaat
    78661 acgacattag aattattatt ttatttggaa aatatcggtc ttgcaagaga agagatggac
    78721 aggcgtttga aggatatact tgagatattc ccgataaaaa atcttttgaa cagaaatata
    78781 tttaatctat ccggcggtga aaaacaaatt ctttgcattg cagcttctta tatagcaggt
    78841 acaaagatta tagttatgga tgagtcttca tcgaatttag atattaaaag cataagtgtt
    78901 ttggcaaaga tgctaaagat attaaaagag aaaggcataa gcataattgt tgcagagcat
    78961 agaatttatt atttgatgga catagttgac cgtgtatttt taatagataa aggaaagctt
    79021 aaaaaaactt atactagaag tgaattttta aagctagata aaaatgaatt aaatgcttta
    79081 agtttaagag ataaagaatt aagtaaatta aaagttcctt atttaaaaga aggtggagag
    79141 tatcagataa aaaatcttag ctacaaattt actgatgatg agtgtttaag cttaaaagat
    79201 atttcgttca agcttgggaa aatttatggc ataataggat ccaacggacg aggaaaatca
    79261 acgcttttaa gatgtttaat aggtcttgag aaaaaatcaa aagaagaaat ttattttaag
    79321 ggagagaagc tatctaaaaa agaaagactc aaaaactctt cacttgttat gcaagatgta
    79381 aatcatcaat tattcacaga tgaagtattc aacgagctta gattaggagt aaagaatttt
    79441 gatgaagaaa aggcgaaaat cattttaaaa gatttaggcc tggacgaatt tattgaaagg
    79501 catccgatga gtttatcagg agggcaaaag caaaggcttg caatagcatc tgttatgtgc
    79561 aagacttctc catttatctt ttttgacgaa ccttcaagtg gtatagatta ttccaatatg
    79621 ataaaaatat ctgaactgat taataagtat aaaaccatgg ataaaataat ttttattgtt
    79681 tcccatgata tagaattttt aaatgaagtg gcagatgaaa tttttgaatt gtaaaataga
    79741 gtctgttaaa catgtctata gaactggtaa attgtctaaa aatttaaaag atactaacac
    79801 atattgatat ttattagaaa attaacttca ggatttttac agtatttata aactttataa
    79861 tatgtattta tagtattaat aatttccata tctttaggga aattatttat ttacttacca
    79921 taattaaaga gatgagagat aaatatcggc agtcttcgga ctgcctttat ttttttactt
    79981 aatttaatgc agtaaatcat acgattgaaa ggaatctgcg ttatatgcta taattaggta
    80041 gttaatctat acatttagaa aggtaaaata tagaattgga gaatgatatg ggattttcat
    80101 ataataaatt gtaacc
//
LOCUS       DAVBDR010000004        78809 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.004, whole genome shotgun sequence.
ACCESSION   DAVBDR010000004 DAVBDR010000000
VERSION     DAVBDR010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 78809)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 78809)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..78809
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.004"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            complement(64..1953)
                     /locus_tag="VQ540_000255"
     CDS             complement(64..1953)
                     /locus_tag="VQ540_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2207 domain-containing protein"
                     /protein_id="HET2544128.1"
                     /translation="MKKTFFLLVLGLFCLLPLSVFAIDFKINSYQGDLYIHADNTAEF
                     RQKIVYQFEEDFKGQIVGLGRAGKMPSGFDIDPHPKVQAAKNGAELADVTSEVTEEAD
                     GYTVRVYNPGQEGDIVEVDLVWNLKNLLFLYDDIAELNWQPLTDSSESIEKFEFHVRG
                     DKGAEKLFFHTGKLFREGTIEKSNLDYTIRLDNLPAKRGVELHAYWPRTDFASARDQG
                     LKGNRLEEFNKIEDSIVREKDQSKQLVTWVLPSILSISLLLSVCFYFIYRRKTTPSVK
                     YAKNHRLYEPPMELEPMVLSEAVYSTSLEEVSPLVKGAGKFTFDQLIQATLLDVIDRG
                     NVSIISEGDAVGLRLVKEDGLSSFEKDCLNLAFSGKKEETLSNLFADYKVSDSLYRRA
                     KVSDEKRIQARGLQLKSSFEEVLNQMQEGVRKRVSFWGLPDYYRPLTGGEKALQVGMG
                     ALTILPLFIGFGLFLYSLDVHGYLYLPLPILGFLGLVLSVFYYWKLRLDNRDGVLNEA
                     GAEVYYLWTSFENMLREIARLDQAELESIVVWNRLLVYATLFGYADKVSHLMKVHQIQ
                     VENPDINLYVAYGWHSLFYHSSAQMSHYASVANTASTYSVSSGSGSSGGGFSGGGGGG
                     SIGAF"
     gene            2091..3656
                     /locus_tag="VQ540_000256"
     CDS             2091..3656
                     /locus_tag="VQ540_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HET2544129.1"
                     /translation="MRKIYLSIFTSLLLMLGLVNVAQADEYLRIGMEAAYAPFNWTQD
                     DDSNGAVKIDGTNQYANGYDVQIAKKIAKDLGKKPLVVKTKWEGLVPALTSGKIDMII
                     AGMSPTAERKQEIAFSSSYYTSEPVLLVKKDSAYASAKSLDDFNGAKITSQQGVYLYD
                     LIAQIPGAKKETAMGDFAQMRQALEAGVIDAYVSERPEALTAEAANSKFKMIQVEPGF
                     KTGEEDTAIAIGLRKNDNRISQINASIETISKDDQVALMDRMIKEQPAEATTTEETSS
                     SFFSQVAKILSENWQQLLRGAGITLLISIVGTIIGLIIGLAIGVFRTAPLSENKAIYG
                     LQKLVGWVLNVYIEIFRGTPMIVQSMVIYYGTAQAFGINLDRTLAAIFIVSINTGAYM
                     TEIVRGGILAVDKGQFEAATALGMTHNQTMCKIVLPQVVRNILPATGNEFVINIKDTS
                     VLNVISVVELYFSGNTVATQTYQYFQTFTIIAVIYFVLTFTVTRILRFIERRMDMDTY
                     TTGANQMQTEDLK"
     gene            3656..4420
                     /locus_tag="VQ540_000257"
     CDS             3656..4420
                     /locus_tag="VQ540_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HET2544130.1"
                     /translation="MTQAILEIKHLKKSYGQNEVLKDISLTVHKGEVISIIGSSGSGK
                     STFLRSINLLETPTDGQILYHGQNVLEKGYDLTQYREKLGMVFQSFNLFENLNVLENT
                     IVAQTTVLKRERTEAEEIAKENLEKVGMGERYWQARPKQLSGGQKQRVAIARALSMNP
                     DAILFDEPTSALDPEMVGEVLKIMQDLAQEGLTMIVVTHEMEFARDVSHRVIFMDKGV
                     IAEEGKPEDLFTNPKEDRTKEFLQRYLILNENQRAN"
     gene            complement(4619..4834)
                     /locus_tag="VQ540_000258"
     CDS             complement(4619..4834)
                     /locus_tag="VQ540_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2544131.1"
                     /translation="MAKSNFEKVESVVGWVRDKKITGYRISKETNAREMSIIALAQGR
                     AKVKNISFETALGLIDFYEKNHEKFED"
     gene            complement(5705..6955)
                     /gene="ilvA"
                     /locus_tag="VQ540_000259"
     CDS             complement(5705..6955)
                     /gene="ilvA"
                     /locus_tag="VQ540_000259"
                     /EC_number="4.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine ammonia-lyase IlvA"
                     /protein_id="HET2544132.1"
                     /translation="MLSSKDIIKAHKVLNGVVVNTPLDYDHYLSEKYGAKIYLKKENA
                     QRVRSFKIRGAYYAISQLSKEERERGVVCASAGNHAQGVAYTCNEMKIPATIFMPITT
                     PQQKIGQVRFFGGDFVTIKLVGDTFDASAKAAQEFTVSENRTFIDPFDDAHVQAGQGT
                     VAYEILEEARKESIDFDAVLVPVGGGGLIAGVSTYIKETSPEIEVIGVEANGARSMKA
                     AFEAGGPVKLKEIDKFADGIAVQKVGQLTYEATRQHIQTLVGVDEGLISETLIDLYSK
                     QGIVAEPAGAASIASLEVLAEYIKGKTICCIISGGNNDINRMPEMEERALIYDGIKHY
                     FVVNFPQRPGALREFVNDILGPNDDITRFEYIKRASKGTGPVLIGIALADKHDYAGLI
                     RRMEGFDPAYINLNGNETLYNMLV"
     gene            complement(7005..7361)
                     /locus_tag="VQ540_000260"
     CDS             complement(7005..7361)
                     /locus_tag="VQ540_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001027901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HET2544133.1"
                     /translation="MNITNLFSIKTGCDETDRQLQKLFFQLDLQLGELTDQLRKLDSN
                     FVPRSQFVDTLDLNDVEYKEILNYFIFHRNDSEESLVEWLYDWISTNRYELPKEFSIR
                     MAHKYHESVTEVFGDE"
     gene            complement(7599..7835)
                     /locus_tag="VQ540_000261"
     CDS             complement(7599..7835)
                     /locus_tag="VQ540_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2544134.1"
                     /translation="MLADQNKADWSYDENAVINIYDDANFEDGRLHMTFEQFFKLAQI
                     AREEGLEIHSPFERAGATKSARYIAKWILRNKKH"
     gene            complement(7942..8964)
                     /gene="ilvC"
                     /locus_tag="VQ540_000262"
     CDS             complement(7942..8964)
                     /gene="ilvC"
                     /locus_tag="VQ540_000262"
                     /EC_number="1.1.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HET2544135.1"
                     /translation="MTVQMEYEKDVKVAALDGKKIAVIGYGSQGHAHAQNLRDSGRDV
                     IIGVRPGKSFDKAKEDGFDTYTVVEATKLADVIMILAPDEIQQELYEAEIAPNLEAGN
                     AVGFAHGFNIHFEFIKVPADVDVFMCAPKGPGHLVRRTYEEGFGVPALYAVYQDATGN
                     AKNIAMDWCKGVGAARVGLLETTYKEETEEDLFGEQAVLCGGLTALIEAGFEVLTEAG
                     YAPELAYFEVLHEMKLIVDLIYEGGFKKMRQSISNTAEYGDYVSGPRVITEQVKENMK
                     AVLADIQNGKFANDFVNDYKAGRPKLTAYREQAANLEIEKVGAELRKAMPFVGKNDDD
                     AFKIYN"
     gene            complement(9030..9506)
                     /gene="ilvN"
                     /locus_tag="VQ540_000263"
     CDS             complement(9030..9506)
                     /gene="ilvN"
                     /locus_tag="VQ540_000263"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002927678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase small subunit"
                     /protein_id="HET2544136.1"
                     /translation="MRRMLTAKLQNRSGVLNRFTGVLSRRQVNIESISVGATEDPNVS
                     RITIIIDVASHDEVEQIIKQLNRQIDVIRIRDITDKPHLEREVILVKMSAPAEKRAEI
                     LAIIQPFRATVVDVAPSSITIQMTGNAEKSEALLRVIRPYGIRNIARTGATGFTRD"
     gene            complement(9499..11199)
                     /locus_tag="VQ540_000264"
     CDS             complement(9499..11199)
                     /locus_tag="VQ540_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase large subunit"
                     /protein_id="HET2544137.1"
                     /translation="MEKISLESPKTGSDLVLETLRDLGVDTIFGYPGGAVLPFYDAIY
                     NFKGIRHILGRHEQGCLHEAEGYAKSTGKLGVAVVTSGPGATNAITGIADAMSDSVPL
                     LVFTGQVARAGIGKDAFQEADIVGITMPITKYNYQVRETADIPRIITEAVHIATTGRP
                     GPVVIDLPKDISALETDFIYSPEVNLPSYQPTLEPNDMQIKKILKQLSKAKKPVLLAG
                     GGISYAEAATELNEFAERYQIPVVTSLLGQGTIATSHPLFLGMGGMHGSFAANIAMTE
                     ADFMISIGSRFDDRLTGNPKTFAKNAKVAHIDIDPAEIGKIISADIPVVGDAKKALQM
                     LLAEPTVHNNTEKWIEKVTKDKNRVRSYDKKERVVQPQAVIERIGELTNGDAIVVTDV
                     GQHQMWTAQYYPYQNERQLVTSGGLGTMGFGIPAAIGAKIANPDKEVVLFVGDGGFQM
                     TNQELAILNIYKVPIKVVMLNNHSLGMVRQWQESFYEGRTSESVFDTLPDFQLMAQAY
                     GIKNYKFDNPETLAQDLEVITEDVPMLIEVDISRKEQVLPMVPAGKSNHEMLGVQFHA
                     "
     gene            complement(11400..13067)
                     /locus_tag="VQ540_000265"
     CDS             complement(11400..13067)
                     /locus_tag="VQ540_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HET2544138.1"
                     /translation="MSKITTSLFQEMVQAASTRLNKQAEYVNSLNVFPVPDGDTGTNM
                     GMTIENGAKEVADKPASTVGEVASILAKGLLMGARGNSGVITSQLFRGFSQAIKDKDE
                     LTGQDLALAFQSGVEVAYKAVMKPVEGTILTVSRGAAIGAKKKAEQTDDTVEVMRAAL
                     EGAKTALAKTPDMLPVLKEVGVVDSGGQGLVFIYEGFLSALTGEYIASEDFVATPANM
                     SEMINVEHHKSVAGHVATEDITFGYCTEIMVALKQGPTYAKDFDYDEFRNYLDELGDS
                     LLVVNDDEIVKVHVHTEDPGLVMQEGLKYGSLVKVKVDNMRNQHEAQVEKEATQVIKS
                     AEEKEYALIAVVAGKGLADIFCSQGVDYVIEGGQTMNPSTEDFIKAVEQVNARNIIFL
                     PNNKNIFMAAQSAAEVLEQPAVVVEARTLPQGMTSLLAFDPSKSIEENQERMTAALSD
                     VVSGSVTTAVRDTTIDGLEIHENDNLGMVDGKILVSNPDMHQTLTETLKHMLDEDSEI
                     VTFYVGEDGSEELANEIAQEIVEEFEDVEVEIHQGQQPVYPYLFSVE"
     gene            complement(13070..13435)
                     /locus_tag="VQ540_000266"
     CDS             complement(13070..13435)
                     /locus_tag="VQ540_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HET2544139.1"
                     /translation="MTVKINTKDGQIELTDEVIATVVGGAATEIFGVVGMASKNALKD
                     NFQALLGKENYSKGVVVKAAEDGSIAVDVYTVLSYGTKISEVSKNIQERVAFSLENQL
                     GITAQTVNVYIQNIKVVGE"
     gene            complement(13592..13780)
                     /locus_tag="VQ540_000267"
     CDS             complement(13592..13780)
                     /locus_tag="VQ540_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008536053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HET2544140.1"
                     /translation="MAKVCYFTGRKTVSGNNRSHAMNQTKRAVKPNLQKVTVLIDGKP
                     KKVWASARALKSGKVERV"
     gene            complement(13896..14072)
                     /locus_tag="VQ540_000268"
     CDS             complement(13896..14072)
                     /locus_tag="VQ540_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 8"
                     /protein_id="HET2544141.1"
                     /translation="MDSDIVVRKSIDELWDLDLTAIPLAAVRDDFYTHNFNSGVLLIN
                     DGMWRAENVTQDLI"
     gene            complement(14183..14332)
                     /locus_tag="VQ540_000269"
     CDS             complement(14183..14332)
                     /locus_tag="VQ540_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 8"
                     /protein_id="HET2544142.1"
                     /translation="MDKVETTIKSLCVHHYNLKFYVFNDDLPREWFQLMEKRLETLNS
                     EIVNV"
     gene            complement(14644..16188)
                     /locus_tag="VQ540_000270"
     CDS             complement(14644..16188)
                     /locus_tag="VQ540_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HET2544143.1"
                     /translation="MNIQEEIKKRRTFAIISHPDAGKTTITEQLLYFGGEIREAGTVK
                     GKKTGTFAKSDWMDIEKQRGISVTSSVMQFDYDGKRVNILDTPGHEDFSEDTYRTLMA
                     VDAAVMVVDSAKGIEAQTKKLFEVVKHRGIPVFTFMNKLDRDGREPLDLLQELEEILG
                     IASYPMNWPIGMGKAFEGLYDLYNQRLELYKGDERFASLEDGDKLFGSNPFYEQVKDD
                     IELLNEAGNEFSEEAILAGELTPVFFGSALTNFGVQTFLEIFLKFAPEPHGHKKTDGE
                     IVDPYDKDFSGFVFKIQANMDPRHRDRIAFVRIVSGEFERGMSVNLPRTGKGAKLSNV
                     TQFMAESRENVINAVAGDIIGVYDTGTYQVGDTLTVGKNKFEFEPLPTFTPEIFMKVS
                     AKNVMKQKSFHKGIEQLVQEGAVQLYKNYQTGEYMLGAVGQLQFEVFKHRMEGEYNAE
                     VVMNPMGKKTVRWIKPEDLDERMSSSRNILAKDRFDQPVFLFENDFALRWFADKYPDV
                     ELEEKM"
     gene            16401..16703
                     /gene="gatC"
                     /locus_tag="VQ540_000271"
     CDS             16401..16703
                     /gene="gatC"
                     /locus_tag="VQ540_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HET2544144.1"
                     /translation="MKITQEEVTHVANLSKLRFSEEETAAFATTLSKIVDMVELLGEV
                     DTTGVAPTTTMADRKTVLRPDVAEEGTDRDRLFKNVPEQDNYYIKVPAILDDGGDA"
     gene            16703..18169
                     /gene="gatA"
                     /locus_tag="VQ540_000272"
     CDS             16703..18169
                     /gene="gatA"
                     /locus_tag="VQ540_000272"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HET2544145.1"
                     /translation="MTFNNKTIEELHNLLVSKEISATELTQATLENIKSREEALNSFV
                     TIAEEQALVQAKAIDEAGIDANNVLSGIPLAVKDNISTDGILTTAASKMLYNYEPIFD
                     ATAVANAKTKGMIVVGKTNMDEFAMGGSGETSHYGATKNAWDHSKVPGGSSSGSAAAV
                     ASGQVRLSLGSDTGGSIRQPAAFNGIVGLKPTYGTVSRFGLIAFGSSLDQIGPFAPTV
                     KENALLLNAIASEDTKDSTSAPVRIADFTSKIGQDIKGMKIALPKEYLGEGIDPEVKE
                     TILNAAKHFEKLGAIVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRAEDA
                     TNLDEIYVNSRSQGFGEEVKRRIMLGTFSLSSGYYDAYYKKAGQVRTLIIQDFEKVFA
                     DYDLILGPTAPSVAYDLDSLNHDPVAMYLADLLTIPVNLAGLPGISIPAGFSQGLPVG
                     LQLIGPKYSEETIYQAAAAFEATTDYHKQQPVIFGGDN"
     gene            18169..19611
                     /gene="gatB"
                     /locus_tag="VQ540_000273"
     CDS             18169..19611
                     /gene="gatB"
                     /locus_tag="VQ540_000273"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HET2544146.1"
                     /translation="MNFETVIGLEVHVELNTNSKIFSPTSAHFGNDQNANTNVIDWSF
                     PGVLPVLNKGVVDAGIKAALALNMDLHKKMHFDRKNYFYPDNPKAYQISQFDEPIGYN
                     GWIEVELEDGTTKKIGIERAHLEEDAGKNTHGTDGYSYVDLNRQGVPLIEIVSEADMR
                     SPEEAYAYLTALKEVIQYAGISDVKMEEGSMRVDANISLRPYGQEKFGTKTELKNLNS
                     FSNVRKGLEYEVQRQAEILRSGGQIRQETRRYDEANKATILMRVKEGAADYRYFPEPD
                     LPLFEISDEWIEEMRTELPEFPKERRARYVSDLGLSDYDASQLTANKVTSDFFEKAVA
                     LGGDAKQVSNWLQGEVAQFLNAEGKTLEQIELTPENLVEMIAIIEDGTISSKIAKKVF
                     VHLAKNGGGAREYVEKAGMVQISDPAILIPIIHQVFADNEAAVADFKSGKRNADKAFT
                     GFLMKATKGQANPQVALKLLAQELAKLKEN"
     gene            19740..20300
                     /gene="efp"
                     /locus_tag="VQ540_000274"
     CDS             19740..20300
                     /gene="efp"
                     /locus_tag="VQ540_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HET2544147.1"
                     /translation="MIEASKLKAGMTFETADGKLIRVLEASHHKPGKGNTIMRMKLRD
                     VRTGSTFDTSYRPEEKFEQAIIETVPAQYLYKMDDTAYFMNTETYDQYEIPVVNVENE
                     LLYILENSDVKIQFYGTEVIGVTVPTTVELTVAETQPSIKGATVTGSGKPATMETGLV
                     VNVPDFIEAGQKLVINTAEGTYVSRA"
     gene            20322..20711
                     /locus_tag="VQ540_000275"
     CDS             20322..20711
                     /locus_tag="VQ540_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HET2544148.1"
                     /translation="MGIEEQLGEIVIAPRVLEKIIAIATAKVEGVHSFSNRSVSDTLS
                     KLSLGRGVYLKNVDEELTADIYLYLEYGVKVPKVAVAIQKAVKDAVRNMADVELAAIN
                     IHVAGIVPDKTPKPELKDLFDEDFLND"
     gene            20704..21126
                     /gene="nusB"
                     /locus_tag="VQ540_000276"
     CDS             20704..21126
                     /gene="nusB"
                     /locus_tag="VQ540_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000203663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HET2544149.1"
                     /translation="MTSPLLESRRQLRKCAFQALMSLEFGTNVETACRFAYTHDREDT
                     DVQLPAFLIDLVSGVQAKKEELDKQITQHLKVGWTIERLTLVERNLLRLGVFEITSFD
                     TPQLVAVNEAIELAKDFSDQKSARFINGLLSQFVTEEQ"
     gene            complement(21175..21552)
                     /locus_tag="VQ540_000277"
     CDS             complement(21175..21552)
                     /locus_tag="VQ540_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000244505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET2544150.1"
                     /translation="MVLSNGQPTFLSTILSFVLLVIIGPVFEETLDRGYFMNTFFPKS
                     KYYLDVILSGLIFGISHLILSHRDPISLLYYSLIGFFFALVYRSTDNLRLTILCHSFF
                     NFLNHAKPIWIFVYNYIYYHFFR"
     gene            complement(21893..22078)
                     /gene="briC"
                     /locus_tag="VQ540_000278"
     CDS             complement(21893..22078)
                     /gene="briC"
                     /locus_tag="VQ540_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm-regulating peptide BriC"
                     /protein_id="HET2544151.1"
                     /translation="MTGTETFTVLSTEDLEQTSGGLAVWEDGYSRWLYYREFAPYMRQ
                     GALNSYIDAWKYGFRTG"
     gene            complement(22237..23004)
                     /locus_tag="VQ540_000279"
     CDS             complement(22237..23004)
                     /locus_tag="VQ540_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HET2544152.1"
                     /translation="MNIAKIVREAREQSRLTTLDFATGIFDEFIQLHGDRSFRDDGAV
                     VGGIGWLGDQAVTVVGIQKGKSLQDNLKRNFGQPHPEGYRKALRLMKQAEKFGRPVVT
                     FINTAGAYPGVGAEERGQGEAIARNLMEMSDLKVPIIAIIIGEGGSGGALALAVADRV
                     WMLENSIYAILSPEGFASILWKDGTRAMEAAELMKITSHELLEMDVVDKVISEVGLSS
                     KELIKSVKKELQTELARLSQKPLEELLEERYQRFRKY"
     gene            complement(23001..23867)
                     /locus_tag="VQ540_000280"
     CDS             complement(23001..23867)
                     /locus_tag="VQ540_000280"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001173351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HET2544153.1"
                     /translation="MALFSKKDKYIRINPNRSVREKPQAKPEVPDELFSQCPGCKHTI
                     YQKDLGSERICPHCSYTFRISAQERLALTIDMGTFKELFTGIESKDPLHFPGYQKKLA
                     SMREKTGLHEAVVTGTALIKGQTVALGIMDSNFIMASMGTVVGEKITRLFEYATVEKL
                     PVVLFTASGGARMQEGIMSLMQMAKISAAVKRHSNAGLFYLTILTDPTTGGVTASFAM
                     EGDIILAEPQSLVGFAGRRVIENTVRESLPEDFQKAEFLLEHGFVDAIVKRRDLPDTI
                     ASLVRLHGGSPR"
     gene            complement(23904..25271)
                     /gene="accC"
                     /locus_tag="VQ540_000281"
     CDS             complement(23904..25271)
                     /gene="accC"
                     /locus_tag="VQ540_000281"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000488661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HET2544154.1"
                     /translation="MFRKILIANRGEIAVRIIRAARELGIATVAVYSTADKEALHTLL
                     ADEAVCIGPGKATESYLNINAVLSAAVLTEAEAIHPGFGFLSENSKFATMCEEVGIKF
                     IGPSGHVMDMMGDKINARAQMIKAGVPVIPGSDGEVHNSEEALIVAEKIGYPVMLKAS
                     AGGGGKGIRKVEKPDDLVSAFETASSEAKANYGNGAMYIERVIYPARHIEVQILGDEH
                     GHVIHLGERDCSLQRNNQKVLEESPSIAIGKTLRHEIGAAAVRAAEFVGYENAGTIEF
                     LLDEASSNFYFMEMNTRVQVEHPVTEFVSGVDIVKEQICIAAGQPLSVKQEDIVLRGH
                     AIECRINAENPAFNFAPSPGKITNLYLPSGGVGLRVDSAVYPGYTIPPYYDSMIAKII
                     VHGENRFDALMKMQRALYELEIEGVQTNADFQLDLISDRNVIAGDYDTSFLMETFLPK
                     YQEKE"
     gene            complement(25283..25705)
                     /gene="fabZ"
                     /locus_tag="VQ540_000282"
     CDS             complement(25283..25705)
                     /gene="fabZ"
                     /locus_tag="VQ540_000282"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HET2544155.1"
                     /translation="MIDIQGIKEALPHRYPMLLVDRVLEVSEDTIVAIKNVTINEPFF
                     NGHFPQYPVMPGVLIMEALAQTAGVLELSKPENKGKLVFYAGMDKVKFKKQVVPGDQL
                     VMTATFVKRRGTIAVVEAKAEVDGKLAASGTLTFAIGN"
     gene            complement(25702..26187)
                     /locus_tag="VQ540_000283"
     CDS             complement(25702..26187)
                     /locus_tag="VQ540_000283"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001052236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HET2544156.1"
                     /translation="MNLNDIKDLMTQFDQSSLREFSYKNGTDELQFSKNEARPVPEVA
                     TQVAPAPVLATPSPVAPTSAPAETVAEEVPAPAEASVASEGNLVESPLVGVVYLAAGP
                     DKPAFVTVGDSVKKGQTLVIIEAMKVMNEIPAPKDGVVTEILVSNEEMVEFGKGLVRI
                     K"
     gene            complement(26190..27425)
                     /gene="fabF"
                     /locus_tag="VQ540_000284"
     CDS             complement(26190..27425)
                     /gene="fabF"
                     /locus_tag="VQ540_000284"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000774039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HET2544157.1"
                     /translation="MKLNRVVVTGYGVTSPIGNTPEEFWNSLATGKIGIGGITKFDHS
                     DFDVHNAAEIQDFPFDKYFVKKDTNRFDNYSLYALYAAQEAVNHANLDVEALNRDRFG
                     VIVASGIGGIKEIEDQVLRLHEKGPKRVKPMTLPKALPNMASGNVAMRFGANGVCKSI
                     NTACSSSNDAIGDAFRSIKFGFQDVMLVGGTEASITPFAIAGFQALTALSTTEDPTRA
                     SIPFDKDRNGFVMGEGSGMLVLESLEHAEKRGATILAEVVGYGNTCDAYHMTSPHPEG
                     QGAIKAIKLALEEAEISPEQVAYVNAHGTSTPANEKGESGAIVAVLGKEVPVSSTKSF
                     TGHLLGAAGAVEAIVTIEAMRHNFVPMTAGTSEVSDYIEANVVYGQGLEKEIPYAISN
                     TFGFGGHNAVLAFKRWENR"
     gene            complement(27447..28178)
                     /gene="fabG"
                     /locus_tag="VQ540_000285"
     CDS             complement(27447..28178)
                     /gene="fabG"
                     /locus_tag="VQ540_000285"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HET2544158.1"
                     /translation="MKLEHKNIFITGSSRGIGLAIAHKFAQAGANIVLNSRGAISEEL
                     LAEFSNYGIKVVPISGDVSDFADAKRMIDQAIAELGSVDVLVNNAGITQDTLMLKMTE
                     ADFEKVLKVNLTGAFNMTQSVLKPMMKAREGAIINMSSVVGLMGNIGQANYAASKAGL
                     IGFTKSVAREVASRNIRVNVIAPGMIESDMTAILSDKIKEATLAQIPMKEFGQAEQVA
                     DLTVFLAGQDYLTGQVIAIDGGLSM"
     gene            complement(28212..29132)
                     /gene="fabD"
                     /locus_tag="VQ540_000286"
     CDS             complement(28212..29132)
                     /gene="fabD"
                     /locus_tag="VQ540_000286"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HET2544159.1"
                     /translation="MTKTAFLFAGQGAQYLGMGRDFYDQYPIVKETIDRASQVLGYDL
                     RYLIDTEEDKLNQTRYTQPAILATSVAIYRLLQEKGYQPDMVAGLSLGEYSALVASGA
                     LDFEDAVALVAKRGAYMEEAAPADSGKMVAVLNTPVEVIEEACQKASELGVVTPANYN
                     TPAQIVIAGEVVAVDRAVELLQEAGAKRLIPLKVSGPFHTALLEPASQKLAETLAQVS
                     FSDFTCPLVGNTEAAVMQKEDIAQLLTRQVKEPVRFYESIGVMQEAGISNFIEIGPGK
                     VLSGFVKKIDQTAHLAHVEDQASLVALLEK"
     gene            complement(29125..30099)
                     /gene="fabK"
                     /locus_tag="VQ540_000287"
     CDS             complement(29125..30099)
                     /gene="fabK"
                     /locus_tag="VQ540_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-[acyl-carrier-protein] reductase FabK"
                     /protein_id="HET2544160.1"
                     /translation="MKTRITELLKIDYPIFQGGMAWVADGDLAGAVSKAGGLGIIGGG
                     NAPKEVVKANIDKIKSLTDKPFGVNIMLLSPFVEDIVDLVIEEGVKVVTTGAGNPSKY
                     MERFHEAGIIVIPVVPSVALAKRMEKIGADAVIAEGMEAGGHIGKLTTMTLVRQVATA
                     ISIPVIAAGGIADGEGAAAGFMLGAEAVQVGTRFVVAKESNAHPNYKEKILKARDIDT
                     TISAQHFGHAVRAIKNQLTRDFELAEKDAFKQEDPDLEIFEQMGAGALAKAVVHGDVE
                     GGSVMAGQIAGLVSKEETAEEILKDLYYGAAKKIQEEASRWAGVVRND"
     gene            complement(30218..30442)
                     /locus_tag="VQ540_000288"
     CDS             complement(30218..30442)
                     /locus_tag="VQ540_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HET2544161.1"
                     /translation="MAVFEKVQEIIVEELGKDASEVTLESTFDDLDADSLDLFQVISE
                     IEDAFDIQIEAENDLKTVGDLVAYVEEQAK"
     gene            complement(30502..31476)
                     /locus_tag="VQ540_000289"
     CDS             complement(30502..31476)
                     /locus_tag="VQ540_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HET2544162.1"
                     /translation="MAFAKISQVAHYVPEQVVTNHDLAQIMDTNDEWISSRTGIRQRH
                     ISRTESTSDLATEVAKKLMAKAGITGEELDFIILATITPDSMMPSTAARVQANIGANK
                     AFAFDLTAACSGFVFALSTAEKFIASGRFQKGLVIGSETLSKAVDWSDRSTAVLFGDG
                     AGGVLLEASEQEHFLAESLNSDGSRSECLTYGHSGLHSPFSDQESADSFLKMDGRTVF
                     DFAIRDVAKSIKQTIDESPIEVTDLDYLLLHQANNRILDKMARKIGVDRAKLPANMME
                     YGNTSAASIPILLSECVEQGLIPLDGSQTVLLSGFGGGLTWGTLILTI"
     gene            complement(31476..31910)
                     /locus_tag="VQ540_000290"
     CDS             complement(31476..31910)
                     /locus_tag="VQ540_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HET2544163.1"
                     /translation="MDYQRINEYLTSIFNNVLVIEEVNLRGSRFKDISIKEMHTIDVI
                     GKAPDVTPSQVSKELMVTLGTVTTSLNNLERKGYIERVRSEQDRRVVHLHLTKKGRLI
                     HRLHKRFHKAMVEKIIDGMSEEEIAVMGKGLTNLYQFLEDLK"
     gene            complement(32004..32789)
                     /locus_tag="VQ540_000291"
     CDS             complement(32004..32789)
                     /locus_tag="VQ540_000291"
                     /EC_number="4.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase"
                     /protein_id="HET2544164.1"
                     /translation="MEHIIYQLEEDLAILTLNRPEVANGFHIPMCEEILEALTLAEEN
                     PAVHFILINANGKVFSVGGDLVEMKRAVDEDDIPSLTKIAELVNTISYKIKQIAKPVL
                     MEVDGAVAGAAANMAVAADFCLATDKAKFIQAFVGVGLAPDAGGIHLLSRSIGVTRAA
                     QLAMTGEALTAEKALEWGLVYRVSEAEKLEKTREQLLKKLRRASSNSYAAIKKLVWES
                     QFKDWQGYATLELNLQKSLAQTEDFKEGVRAHSERRRPKFTGK"
     gene            33114..34478
                     /locus_tag="VQ540_000292"
     CDS             33114..34478
                     /locus_tag="VQ540_000292"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HET2544165.1"
                     /translation="MKVVKFGGSSLASASQLEKVLNIVKSDSERRFVVVSAPGKRNAE
                     DTKVTDALIKYYRDYVAGNDISKSQSWIIDRYAAMVSELGLKPAVLEKISKSIHALAT
                     LPIEENEFLYDTFLAAGENNNAKLIAAYFNQNGIDARYMHPREAGIVVTSEPGHARII
                     PSSYDKIEELTNTNEVLVIPGFFGVTKENQICTFSRGGSDITGSIIAAGVKADLYENF
                     TDVDGIFAAHPGIIHQPHSIPELTYREMRELAYAGFSVLHDEALLPAYRGKIPLVIKN
                     TNNPDHPGTRIVLKHSNDEFPVVGIAGDSGFVSINMSKYLMNREVGFGRKVLQILEEL
                     NIGWEHMPTGIDDLSIILRSRQLTPIKEEEILRQLVQKAKVDHAEIEHDLSIIMIVGE
                     KMKSHIGVTATATRALSENKINIQMMSQGSSEVSIMFVVNKDQEKAAIKALYNAFFGE
                     SKED"
     gene            34481..34852
                     /locus_tag="VQ540_000293"
     CDS             34481..34852
                     /locus_tag="VQ540_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HET2544166.1"
                     /translation="MAQSLNKTVLLSTTGTSYLSIAGKVGKFLVGDQALEFYPDVNVE
                     QFIQIPWSHINQIGANVTGRKISRHFEVFTDKGKFLFASKDSGAILKIAREKLGNDKV
                     VKLPTLIQTISQKFKNLFAKK"
     gene            35066..36340
                     /gene="serS"
                     /locus_tag="VQ540_000294"
     CDS             35066..36340
                     /gene="serS"
                     /locus_tag="VQ540_000294"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000884256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HET2544167.1"
                     /translation="MLDIKRIRTDFEAVAEKLATRGVDAAVLNEMKEIDAKRRNILVK
                     VETLKAERNTVSAEIAQAKRNKENTDDKIAAMQNLSAEVKALDAELAEIDAKLTEFTT
                     TLPNIPADSVPVGTDEDDNVEVRRWGTPREFDFEPKAHWDLGEDLGILDWERGGKVTG
                     ARFLFYKGLGARLERAIYNFMLDEHGKEGYTEVITPYIVNHDSMFGTGQYPKFKEDTF
                     ELSDTNFVLIPTAEVPLTNYYRDEILDGKDLPIYFTAMSPSFRSEAGSAGRDTRGLIR
                     LHQFHKVEMVKFAKPEESYEELEKMTANAENILQKLNLPYRVVALSTGDMGFSAAKTY
                     DLEVWIPAQNNYREISSCSNTEDFQARRAQIRYRDEADGKVKLLHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTIPEALRPYMGGAEVIKP"
     gene            complement(36365..37264)
                     /locus_tag="VQ540_000295"
     CDS             complement(36365..37264)
                     /locus_tag="VQ540_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000735961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HET2544168.1"
                     /translation="MKKLPLVFSGCLLGLAGAGNLILDTLPVLSHLFSLTGLVLWIYF
                     LILHLFNWKETKQELTKPPLLSGMATFPMAGMILSTYVFRVFSYLPLVAQGIWWFSFL
                     LDLTLIAGFTIKFACSGRRVHATPSWTVLYVGIAVAALTYPLVGIIEIAYATLSFGFL
                     LTFYLYPLIYSDLKKHPLPLALLGQEGIYCAPFSLLLASLVRVGGTSLPTWVLIVMIL
                     ASQSFFFFVLTRLPNILKQGFQPAFSALTFPTIITATSLKMAQGILKLPFLDYLVLAE
                     TIICLTILFFVLGAYLIWLRKKV"
     gene            complement(37374..37922)
                     /locus_tag="VQ540_000296"
     CDS             complement(37374..37922)
                     /locus_tag="VQ540_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000206764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HET2544169.1"
                     /translation="MTTFTIHTVESAPAEVKEILETVEKDNNGYIPNLIGLLANAPTV
                     LEAYQIVSSIHRRNSLTPVEREVVQITAAVTNGCAFCVAGHTAFSIKQIQMNDDLIQA
                     LRNRTPIETDPKLDTLAKFTLAVINTKGRVGDEALSEFLEAGYTQQNALDVVFGVSLA
                     ILCNYANNLANTPINPELQPYA"
     gene            complement(38140..39462)
                     /locus_tag="VQ540_000297"
     CDS             complement(38140..39462)
                     /locus_tag="VQ540_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:alanine symporter family protein"
                     /protein_id="HET2544170.1"
                     /translation="MLELLKSIDAFAWGPPLLILLVGTGIYLTMRLGLLQVLRLPKAF
                     QLIFIQDKGHGDVSSFAALCTALASTVGTGNIIGVATAIKVGGPGALFWMWMAAFFGM
                     ATKYAEGLLAIKYRTKDDHGAVAGGPMHYILLGMGEKWRPLAVLFAVAGVLVALLGIG
                     TFTQVNSITESIQNTTTISPAITALVLSVFVAIAVFGGLKSISKVSTTVVPFMALIYI
                     LGTLTVIFFNIGKIPGTIALVFTSAFSPLAAVGGFAGASVRMAIQNGVARGVFSNESG
                     LGSAPIAAAAAKTNEPVEQGLISMTGTFIDTLIICTLTGLTILVTGVWSGDLNGVALT
                     QSAFSTVFSHFGPALLTIFLVLFAFTTILGWNYYGERCFEFLFGARFIWLYRVFFVLM
                     VLLGGFIELDMVWIIADIVNALMALPNLIALLVLSPVVIAETKKYFDK"
     regulatory      complement(39553..39641)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            complement(39805..42141)
                     /locus_tag="VQ540_000298"
     CDS             complement(39805..42141)
                     /locus_tag="VQ540_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HET2544171.1"
                     /translation="MNKKILETLEFDKVKALFDPHLLTEQGLEQLRQLAPTAKADKIK
                     QAFAEMKEMQALFVEQPHFTILSTKEIAGVCKRLEMGADLNIEEFLLLKRVLLASREL
                     QSFYANLENVSLEELALWFEKLHDFPQLQGNLQAFNDAGFIENFASEELARIRRKIHD
                     SESQVRDVLQDLLKQKAQMLTEGIVASRNGRQVLPVKNTYRNKIAGVVHDISASGNTV
                     YIEPREVVKLSEEIASLRADERYEMLRILQEISERVRPHAAEIANDAWIIGHLDLIRA
                     KVRFIQERQAVVPQLSENQEIQLLHVCHPLVKNAVANDVHFGQDLTAIVITGPNTGGK
                     TIMLKTLGLTQVMAQSGLPILADKGSRVGIFEEIFADIGDEQSIEQSLSTFSSHMTNI
                     VDILGKVNQHSLLLLDELGAGTDPQEGAALAMAILEDLRLRQIKTMATTHYPELKAYG
                     IETAFVQNASMEFDTATLRPTYRFMQGVPGRSNAFEIAKRLGLSEVIVGDASQQIDQD
                     NDVNRIIEQLEEQTLESRKRLDNIREVEQENLKMNRALKKLYNELNREKETELNKARE
                     QAAEIVDMALSESDQILKNLHSKSQLKPHEIIEAKAKLKKLAPEKVDLSKNKVLQKAK
                     KKRAPKVGDDIVVLSYGQRGTLTSQLKDGRWEAQVGLIKMTLEEKEFDLVQAQQEKPV
                     KKKQVNVVKRTSGRGPQARLDLRGKRYEEAMNELDTFIDQALLNNMAQVDIIHGIGTG
                     VIREGVTKYLQRNKHVKSFGYAPQNAGGSGATIVTFKG"
     gene            complement(42245..42793)
                     /locus_tag="VQ540_000299"
     CDS             complement(42245..42793)
                     /locus_tag="VQ540_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000622948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HET2544172.1"
                     /translation="MISFLLLLVLVWGFYIGYRRGLLLQVYYLISAMASAFMAGQFYK
                     GLGEQFHLLLPYANSQEGQGTFFFPSDQLFQLDKVFYAGIGYLLVFGIFYSIGRLLGL
                     LLHLIPSKKLGGKLFQVSAGILSMLVTLFVLQMALTILATIPMAVIQNPLEKSIVAKH
                     IIQSIPITTSWLKQIWVTNLIG"
     gene            complement(42790..43092)
                     /gene="zapA"
                     /locus_tag="VQ540_000300"
     CDS             complement(42790..43092)
                     /gene="zapA"
                     /locus_tag="VQ540_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HET2544173.1"
                     /translation="MANLNRFKFTFGKKSLTLTSEHDNLFMEEIAKVATEKYQAIKEQ
                     MPSADDETIALLLAVNCLSTQLSREIEFDDKEQELEELRHKLVTCKQEQSKIEDSL"
     gene            43179..44060
                     /locus_tag="VQ540_000301"
     CDS             43179..44060
                     /locus_tag="VQ540_000301"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HET2544174.1"
                     /translation="MASITLTPSEKDIQAFLEHYQTSLAPSKNPYIRYFLKLPQATVS
                     IYTSGKILLQGEGAEKYASFFGYQLVEENRGQNLPLIGTDEVGNGSYFGGLAVVAAFV
                     TSDQHDFLRKLGVGDSKTLTDQKIRQIAPILKEKIQHQALLLSPSKYNEVIGDRYNAV
                     SVKVALHNQAIYLLLQKGVQPEKIVIDAFTSAKNYDKYLAQEANRFSNPISLEEKAEG
                     KYLSVAVSSVIARDLFLENLENLGRELGYQLPSGAGTASDKVASQILQAYGMQGLSFC
                     AKLHFKNTEKAKKRLER"
     gene            44064..44678
                     /gene="lepB"
                     /locus_tag="VQ540_000302"
     CDS             44064..44678
                     /gene="lepB"
                     /locus_tag="VQ540_000302"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HET2544175.1"
                     /translation="MNSFKNFLKEWGLFLLILSLLALSRIFFWSNVRVEGHSMDPTLA
                     DGEILFVVKHLPIDRFDIVVAHEEDGNKDIVKRVIGMPGDTIRYENDKLYINDKETDE
                     PYLADYIKRFKDDKLQSTYSGKGFEGNKGTFFRSIAQKAQAFTVDVNYNTNFSFTVPE
                     GEYLLLGDDRLVSSDSRHVGTFKAKDITGEAKFRFWPITRIGTF"
     gene            44957..47323
                     /locus_tag="VQ540_000303"
     CDS             44957..47323
                     /locus_tag="VQ540_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HET2544176.1"
                     /translation="MEVYFSGTIERIIFENPSNFYRILLLEIDDTDAEDFDDFEIIVT
                     GTMADVIEGEDYTFWGQIVQHSKYGEQLQISRYDRAKPTSKGLVKYFSSSHFKGIGLK
                     TAQKIVDTYGENTIDEILQHPEKLEGIAGLSAKNREAFVSTLRLNYGTEMVLSKLANY
                     GIPNKLAFQIQDFYKEETLDVVENYPYQLVEDIKGLGFTIADQLAEELGIESQAPERF
                     RAGLVHSLFQACMETGDTYVEARDLLEQTLTLLESSRPVELDPSQVAQELSYLIEEDK
                     VQQIDTKIFDNSLFFAEEGIRSHLVRILEKGKQKSHDLETIQKHITTIEEELGIEYDN
                     IQKQAICDAIQNKVFILTGGPGTGKTTVINGIIAVYALLEGLDFRKKSNLPILLAAPT
                     GRAARRMNELTGLPSATIHRHLGMTGDDDTSHLEDYLDADFIIVDEFSMVDTWLANQL
                     FSNISSNSKILIVGDSDQLPSVSPGQVLADLLHIPLIPQTHLEKIYRQSKESTIVTLA
                     SQIRQGILPADFTQKKADRSYFEIASGHIPATIEKILGAALRNGIPARDIQVLAPMYR
                     GTAGIDAINQLMQDLLNPPQKDQLSFEAPQCHYRKGDKVIHLVNDAEINVFNGDLGAI
                     TDLIPGKYTESKQDEIVIDFDGNEVSYPRNEWYKIRLAYAMSIHKSQGSEFPVVILPI
                     TSASRRMLERNLIYTAITRAKSKLILLGELQAFDYATQHIGTARKTYLIERFSDLLEN
                     VEEKQQAVSETVTSSASEQSYILTEENWDSIPAMIGITDTDLKEIFGK"
     gene            complement(47371..48654)
                     /locus_tag="VQ540_000304"
     CDS             complement(47371..48654)
                     /locus_tag="VQ540_000304"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HET2544177.1"
                     /translation="MSVSFENKETNRGVLTFTISQDQIKPELDRVFKSVKKSLNVPGF
                     RKGHLPRPIFDKKFGEESLYQDVMNALLPNAYEAAVKEAGLEVVAQPKIDVTSMEKGQ
                     DWVIAAEVVTKPEVKLGDYKNLEVSVDVEKEVTDADVEERIERERNNLAELVIKEAAA
                     EDGDTVVIDFVGSIDGVEFDGGKGENFSLGLGSGQFIPGFEDQLVGHSAGETVDVIVT
                     FPEDYQAEDLAGKEAKFVTTIHEVKAKEVPALDDELAKDIDEEVETLADLKEKYRKEL
                     AAAKEEAYKDAVEGAAIDTAVENAEIVELPEEMIHEEVHRSVNEFLGNLQRQGINPDM
                     YFQITGTTQEDLHNQYQAEAESRTKTNLVIEAVAKAEGFDASEEEIQKEVEQLAADYN
                     MEVAQVQNLLSADMLKHDITIKKAVELITSTATVK"
     gene            complement(48848..49207)
                     /locus_tag="VQ540_000305"
     CDS             complement(48848..49207)
                     /locus_tag="VQ540_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HET2544178.1"
                     /translation="MDSPKSLASYRVIGISDRVLEILKEYLLLEEGDYIFTNNGSPLM
                     ITCFNYFLKNRFRKSEIKKDDFVLTAHVFRYSHISLLAELEVPITAIMDRVDYTNETK
                     ILSVYTHVTEKMKSNIT"
     gene            complement(49506..50135)
                     /locus_tag="VQ540_000306"
     CDS             complement(49506..50135)
                     /locus_tag="VQ540_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine protease"
                     /protein_id="HET2544179.1"
                     /translation="MVLSKYYGVADGMNVEGRGSANFIKDNVLITAAHNYYRHDYGKE
                     ADDIYVLPTVSPSQEPFGKIKVKEVRYLKEFRNLNSKDAREYDLALLILEEPIGAKLG
                     TLGLPTSQKNLTGITVTITGYPSYNFKVHQMYTDKKQVLSDDGMFLDYQVDTLEGSSG
                     STVYDASHRVVGVHTLGDGANQINSAVKLNERNLPFIYSVLKGYSLEGW"
     gene            complement(50180..50419)
                     /locus_tag="VQ540_000307"
     CDS             complement(50180..50419)
                     /locus_tag="VQ540_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2544180.1"
                     /translation="MKKTVYKKLGISIIASTLLASQLSTVSALSVISSTGEEYEVSET
                     LEKGPGSNDSSLSEISPTYGSYYQKQSEVLSVMMI"
     gene            complement(50569..50835)
                     /locus_tag="VQ540_000308"
                     /pseudo
     CDS             complement(50569..50835)
                     /locus_tag="VQ540_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060522.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
     gene            complement(50860..51168)
                     /locus_tag="VQ540_000309"
     CDS             complement(50860..51168)
                     /locus_tag="VQ540_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HET2544181.1"
                     /translation="MDWDFADTCWEKEPRKYQYVAANYLKAMQSYLKETDLPKLEQLV
                     VTKSWWDTVDILDRVVGSLVYEHPELEEIILILFENLFKPRQLYLQPQNSVLRLQIAS
                     "
     gene            complement(51093..51335)
                     /locus_tag="VQ540_000310"
     CDS             complement(51093..51335)
                     /locus_tag="VQ540_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HET2544182.1"
                     /translation="MSLADLLEELEAAKDSKKARPMEAYMRHQFSFLGIAVPERNKLY
                     KNIYQKRKKQRLSIGILQTLAGKRSLENTNMWLLTI"
     gene            complement(51336..51968)
                     /locus_tag="VQ540_000311"
     CDS             complement(51336..51968)
                     /locus_tag="VQ540_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET2544183.1"
                     /translation="MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEASNGSQGIDLALE
                     LRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIVTSYLDNEKIMPVLDAGAKGYML
                     KTSSADELLHAVSKVAAGELAIEQEVSKKVEYHRNHMELHEELTARERDVLQLIAKGY
                     ENQRIADDLFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGQEEF"
     gene            complement(51982..52977)
                     /locus_tag="VQ540_000312"
     CDS             complement(51982..52977)
                     /locus_tag="VQ540_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET2544184.1"
                     /translation="MKKQAYVIIALTSFLFVFFFSHSLLEILDFDWSIFLYDVEKTEK
                     FVFLLLVFSMSMTCLLALFWRGIEELSLRKMQANLKRLLAGQEVVQVVDPDLDASFKS
                     LSGKLNLLTEALQKAENHSLDQEEEIIEKERKRIARDLHDTVSQELFAAHIILSGISQ
                     QALKLDREKMQTQLQSVTAILETAQKDLRVLLLHLRPVELEQKSLIEGIQILLKELED
                     KSDLRVSLKQNMTKLPKKIEEHIFRILQELISNTLRHAQASCLDVYLYQTDVELQLKV
                     VDNGIGFRLGSLDDLSYGLRNIKERVEDMAGTVQLLTAPKQGLAVDIRIPLLDKE"
     gene            complement(52974..53672)
                     /locus_tag="VQ540_000313"
     CDS             complement(52974..53672)
                     /locus_tag="VQ540_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein"
                     /protein_id="HET2544185.1"
                     /translation="MRKFKIFLFIEACLLTGALILMVSEHFSRFLLILFLFLLLIRYY
                     TGKEGNNLLLVAATILFFFIVMLNPFVILAIFVAVIYSLFLLYPMMNQEKEQTNLVFE
                     EVVTVKKEKNRWFGNLHHFSSYQTCQFDDINLFRFMGKDTIHLERVILTNHDNVIILR
                     KMVGTTKIIVPVDVEVSLSVNCLYGDLTFFNQPKRALRNEHYHQETKDYLKSNKSVKI
                     FLTTMIGDVEVVRG"
     gene            complement(53750..54760)
                     /locus_tag="VQ540_000314"
     CDS             complement(53750..54760)
                     /locus_tag="VQ540_000314"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000210649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HET2544186.1"
                     /translation="MTTNRKDEHILYALEQKSSYNSFDEVELIHSSLPLYNLDEIDLS
                     TEFAGRKWDFPFYINAMTGGSNKGREINQKLAQVAESCGILFVTGSYSAALKNPTDDS
                     FSVKSSHPNLLLGTNIGLDKPVELGLQTVEEMNPVLLQVHVNVMQELLMPEGERKFRS
                     WQSHLADYSKQIPVPIVLKEVGFGMDAKTIERAYEFGVRTVDLSGRGGTSFAYIENRR
                     SGQRDYLNQWGQSTMQALLNAQEWKDKVELLVSGGVRNPLDMIKCLVFGAKAVGLSRT
                     VLELVETYTVEEVIGIVQGWKADLRLIMCSLNCATIADLQKVDYLLYGKLKEAKDQMK
                     KA"
     gene            complement(54744..55751)
                     /locus_tag="VQ540_000315"
     CDS             complement(54744..55751)
                     /locus_tag="VQ540_000315"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000562378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HET2544187.1"
                     /translation="MIAVKTCGKLYWAGEYAILEPGQLALIKDIPIYMRAEIAFSDSY
                     RIYSDMFDFAVDLTPNPDYSLIQETIALMGDFLAVRGQNLRSFSLEICGKMEREGKKF
                     GLGSSGSVVVLVVKALLALYDVSVDQELLFKLTSAVLLKRGDNGSMGDLACIVAEDLV
                     LYQSFDRQKVAAWLEEENLATVLERDWGFSISQVKPTLECDFLVGWTKEVAVSSHMVQ
                     QIKQNINQNFLSSSKETVVSLVEALEQGKSEKIIEQVEVASKLLEGLSTDIYTPLLRQ
                     LKEASQDLQAVAKSSGAGGGDCGIALSFDAQSTKTLKNRWADLGIELLYQERIGHDDK
                     S"
     gene            complement(55738..56691)
                     /gene="mvaD"
                     /locus_tag="VQ540_000316"
     CDS             complement(55738..56691)
                     /gene="mvaD"
                     /locus_tag="VQ540_000316"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HET2544188.1"
                     /translation="MDREPVTVRSYANIAIIKYWGKKKEKEMVPATSSISLTLENMYT
                     ETTLSPLPANVIADEFYINGQLQNEVEHAKMSKIIDRYRPAGEGFVRIDTQNNMPTAA
                     GLSSSSSGLSALVKACNAYFKLGLDRSQLAQEAKFASGSSSRSFYGPLGAWDKDSGEI
                     YSVETDLKLAMIMLVLEDKKKPISSRDGMKLCVETSTTFDDWVRQSEKDYQDMLIYLK
                     ENDFAKIGELTEKNALAMHATTKTASPAFSYLTDASYEAMDFVRQLREKGEACYFTMD
                     AGPNVKVFCQEKDLEHLSEIFGQRYRLIVSKTKDLSQDDCC"
     gene            complement(56673..57551)
                     /gene="mvk"
                     /locus_tag="VQ540_000317"
     CDS             complement(56673..57551)
                     /gene="mvk"
                     /locus_tag="VQ540_000317"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HET2544189.1"
                     /translation="MTKKVGVGQAHSKIILIGEHAVVYGYPAISLPLLEVEVTCKVVP
                     AESPWRLYEEDTLSMAVYASLEYLDITEACIRCEIDSAIPEKRGMGSSAAISIAAIRA
                     VFDYYQADLPHDVLEILVNRAEMIAHMNPSGLDAKTCLSDQPIRFIKNVGFTELEMDL
                     SAYLVIADTGVYGHTREAIQVVQNKGKDALPFLHALGELTQQAEVAISQKDAEGLGQI
                     LSQAHLHLKEIGVSSPEADFLVETTLSHGALGAKMSGGGLGGCIIALVTNLTHAQELA
                     ERLEEKGAVQTWIESL"
     gene            complement(57673..58002)
                     /locus_tag="VQ540_000318"
     CDS             complement(57673..58002)
                     /locus_tag="VQ540_000318"
                     /inference="COORDINATES: protein motif:HMM:NF024736.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2544190.1"
                     /translation="MTRKAYDTDLNDQEWAKIEPYFSKHRTYKWPKRVLVNETLYVTK
                     TGCQWRMIPHDFPLYLTVWSFFRRSMTTGWFQVNGRWYYAYSSGALAVNTTVDGYSVN
                     YNGEWVQ"
     gene            58664..59000
                     /locus_tag="VQ540_000319"
                     /pseudo
     CDS             58664..59000
                     /locus_tag="VQ540_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811282.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic-modifying protein"
     gene            58900..59487
                     /locus_tag="VQ540_000320"
     CDS             58900..59487
                     /locus_tag="VQ540_000320"
                     /inference="COORDINATES: protein motif:HMM:NF017000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2544191.1"
                     /translation="MTILLKLSSTIVYGEIYHYFLQRDTAKESILDYSFAHGYCEIAY
                     ALFAYSKVLEPSMFYNDLHTFHAELKKLLEKVTSNTENLGNLQLSWCEGISGIILYLC
                     MYDCDGNKDIISKYQEFVFNHHLKMMTGYCHGITSLLQTTVYNQNKLLMKKIQQVILA
                     CSERDDHGLLMFQGDSGKADLFDFGIGSRGYIGVY"
     gene            59530..60762
                     /locus_tag="VQ540_000321"
     CDS             59530..60762
                     /locus_tag="VQ540_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HET2544192.1"
                     /translation="MKLFWTNNIYRQLLLNSCFSSFGDSIFYLAIINYVAQYNFAPLA
                     ILLISISEMVPLLSQLFLGILGDFQENRVKHALCIAKIKILLYAILTVFLVLSPFSLV
                     SVIMIVIINLISDTLSYLSAYMMNALYISVIKDDLHDAMGFRQSLMRVVHIVANLAGA
                     FLINVISIQTISLINTLTFVIAFLGLYVIRHTLYEVEKRIEMSHTALSFKKYFQHLKQ
                     SLAVLLRLKDTVILLFLTTSMIAILDVSPRLIALRFIQQTLAQLSIGQLFALLSIIMS
                     CGAILGNMTSSNLFKNIRFTHLLVFCEISLLALITSILCQAYIVIFVTSFISSTIIGI
                     LSPRLQAAVFAHIPSDKMGTVGSALSTVDILAPSLLSLLALSIASGVSVQLALIFLYL
                     ILIALIFCQWLVKFNTHN"
     gene            complement(60880..61836)
                     /gene="cbpC"
                     /locus_tag="VQ540_000322"
     CDS             complement(60880..61836)
                     /gene="cbpC"
                     /locus_tag="VQ540_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpC"
                     /protein_id="HET2544193.1"
                     /translation="MKLLKKMMQVLLAVFFFGLLATNTVFANTTGGRFVDKDNRKYYV
                     KDDHKAIYWHKIDGKTYYFGDIGEMVVGWQYLEIPGTGYRDDLFDNRPVFEIGLQEKW
                     YYFGQDGALLEQTDKQVLEAKTSENTGKVYGEQYPLSAEKRTYYFDNNYAVKTGWIYE
                     DGNWYYLNKLGNFGDDSYNPLPIGEVAKGWTQDFHVTIDIDRSKPAPWYYLRSSGAMA
                     TGWYQEGTTWYYLDQPNGDMKTGWQNLGNKWYYLRSSGAMATGWYQDGSTWYYLNAGN
                     GDMKTGWFQVNGNWYYAYSSGALAVNTTVDGYSVNYNGEWVR"
     gene            complement(61934..62623)
                     /locus_tag="VQ540_000323"
     CDS             complement(61934..62623)
                     /locus_tag="VQ540_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000518023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET2544194.1"
                     /translation="MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQ
                     TDYDLILLNVNLGDMMAQDFAEKLSRTKPASVIMILDHWEDLQEELEVVQRFAVSYIY
                     KPVFIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
                     REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIK
                     TVRGVGYTMQE"
     gene            complement(62635..64059)
                     /gene="gndA"
                     /locus_tag="VQ540_000324"
     CDS             complement(62635..64059)
                     /gene="gndA"
                     /locus_tag="VQ540_000324"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HET2544195.1"
                     /translation="MTKANFGVVGMAVMGRNLALNIESRGYTVAIYNRSKEKTEDVIA
                     CHPEKNFVPSYDVESFVNSIEKPRRIMLMVQAGPGTDATIQALLPHLDKGDILIDGGN
                     TFYKDTIRRNEELANSGINFIGTGVSGGEKGALEGPSIMPGGQKEAYELVSDVLEEIS
                     AKAPEDGKPCVTYIGPDGAGHYVKMVHNGIEYGDMQLIAESYDLMQHLLGLSAEDMAE
                     IFTEWNKGELDSYLIEITADILSRKDDEDQDGPIVDYILDAAGNKGTGKWTSQSSLDL
                     GVPLSLITESVFARYISTYKEERVHASKVLPKPAAFNFEGDKAELIEKIRQALYFSKI
                     ISYAQGFAQLRVASKENNWNLPFADIASIWRDGCIIRSRFLQKITDAYNRDADLANLL
                     LDEYFLDVTAKYQQAVRDIVALAVQAGVPVPTFSAAITYFDSYRSADLPANLIQAQRD
                     YFGAHTYQRKDKEGTFHYSWYDEK"
     gene            complement(64135..65529)
                     /gene="mapZ"
                     /locus_tag="VQ540_000325"
     CDS             complement(64135..65529)
                     /gene="mapZ"
                     /locus_tag="VQ540_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mid-cell-anchored protein MapZ"
                     /protein_id="HET2544196.1"
                     /translation="MSKKRRNRHKKEGQEPQFDFDEAKELTVGQAIRKNEEVEAGVLP
                     EDSILDKYVKQHRDEIEADKFATRQYKKEEFVETQSLDDLIQEMREAVEKSEASSEEV
                     PSSEDILLPLPLDDEEQGLDPLLLDDENPTEMTEEVEEEQNLSRLDQEDSEKKSKKGF
                     ILTVLALVSVIICVSAYYVYRQVARSTKEIETSQSTTANQSDVDDFNTLYDAFYTNSN
                     KTALKNSQFDKLSQLKTLLDKLEGSREHTLAKSKYDSLVTQIKAIQDVNAQFEKPAIV
                     DGVLDTNAKAKSDAKFTDIKTGNTELDKVLDKAISLGKSQQTSTSSSSSSQTSSSSSS
                     QASSNTTSEPKPSSSNETRSSRSEVNMGLSSAGVAVQRSASRVAYNQSAIDDSNNSAW
                     DFADGVLEQILATSRSRGYITGDQYILERVNIVNGNGYYNLYKPDGTYLFTLNCKTGY
                     FVGNGAGHADDLDY"
     gene            complement(65542..66699)
                     /locus_tag="VQ540_000326"
     CDS             complement(65542..66699)
                     /locus_tag="VQ540_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HET2544197.1"
                     /translation="MKKEFNLIATVAAGLEAVVGREVRELGYDCQVENGRVRFQGDVR
                     AIIETNLWLRAADRIKIIVGTFPAKTFEELFQGVFALDWENYLPLGARLPISKAKCVK
                     SKLHNEPSVQAISKKAVVKKLQKHYARPEGVPLMENGPEFKIEVSILKDVATVMIDTT
                     GSSLFKRGYRTEKGGAPIKENMAAAILQLSNWYPDKPLIDPTCGSGTFCIEAVMIARK
                     MAPGLRRSFAFEEWNWISDRLIQEVRTEAAKKVERKLELDIMGCDIDARMVEIAKANA
                     QAAGVAGDITFKQMRVQDLRSDKINGVIISNPPYGERLSDDAGVTKLYAEMGQVFAPL
                     KTWSKFILTSDEAFESKYGSQADKKRKLYNGTLKVDLYQYFGQRVKRQEVK"
     gene            complement(66784..67164)
                     /gene="rnpB"
                     /locus_tag="VQ540_000327"
     ncRNA           complement(66784..67164)
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="VQ540_000327"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            complement(67185..67514)
                     /gene="gpsB"
                     /locus_tag="VQ540_000328"
     CDS             complement(67185..67514)
                     /gene="gpsB"
                     /locus_tag="VQ540_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HET2544198.1"
                     /translation="MASIIFSAKDIFEQEFGREVRGYNKVEVDEFLDDVIKDYETYAA
                     LVKSLRQEIADLKEELTRKPKPSPVQAEPLEAAITSSMTNFDILKRLNRLEKEVFGKQ
                     ILDNSDF"
     gene            complement(67584..68111)
                     /locus_tag="VQ540_000329"
     CDS             complement(67584..68111)
                     /locus_tag="VQ540_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HET2544199.1"
                     /translation="MATALVLGYSAFDLGLFSDKDPRLKLIKKAIRKDLEAMAADGVS
                     WLVFTGSLGFEYWVLEVAQEMKTEYGFQLATIFAFETHGENWNEGNQMKLSRFKQVDF
                     VKYAYPRYEHKGQLRDYQQFLLENTTSSYLFYDEENETKLAYFYQKMKNQEDYFIKRL
                     TFDQLNELAENFSEN"
     gene            68177..68773
                     /gene="recU"
                     /locus_tag="VQ540_000330"
     CDS             68177..68773
                     /gene="recU"
                     /locus_tag="VQ540_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HET2544200.1"
                     /translation="MINYPHKVSSQKRQTSLSQPKNFANRGMSFEKMINATNDYYLSQ
                     GLAVIHKKPTPIQIVQVDYPQRSRAKIVEAYFRQASTTDYSGVYNGYYIDFEVKETKQ
                     KRAIPMKNFHPHQIQHMEQVLAQQGICFVLLHFSSQQETYLLPAFDLIRFYHQDKGQK
                     SMPLEYIREYGYEIKAGAFPQIPYLNVIKEHLLGGKTR"
     gene            68770..70929
                     /locus_tag="VQ540_000331"
     CDS             68770..70929
                     /locus_tag="VQ540_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001040003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 1A"
                     /protein_id="HET2544201.1"
                     /translation="MNKPTILRLIKYLSISFLSLVIAAIVLGGGVFFYYVSKAPSLSE
                     SKLVATTSSKIYDNKNQLIADLGSERRVNAQANDIPTDLVKAIVSIEDHRFFDHRGID
                     TIRILGAFLRNLQSNSLQGGSTLTQQLIKLTYFSTSTSDQTISRKAQEAWLAIQLEQK
                     ATKQEILTYYINKVYMSNGNYGMQTAAQNYYGKDLNNLSLPQLALLAGMPQAPNQYDP
                     YSHPEAAQDRRNLVLSEMKNQGYISAEQYEKAVNTPITDGLQSLKSASNYPAYMDNYL
                     KEVINQVEEETGYNLLTTGMDVYTNVDQEAQKHLWDIYNTDEYVAYPDDELQVASTIV
                     DVSNGKVIAQLGARHQSSNVSFGINQAVETNRDWGSTMKPITDYAPALEYGIYDSTAT
                     IVHDEPYNYPGTNTPVYNWDRGYFGNITLQYALQQSRNVPAVETLNKVGLNRAKTFLN
                     GLGIDYPSIHYSNAISSNTTESDKKYGASSEKMAAAYAAFANGGTYYKPMYIHKVVFS
                     DGSEKEFSNVGTRAMKETTAYMMTDMMKTVLTYGTGRNAYLAWLPQAGKTGTSNYTDE
                     EIENHIKTSQFVAPDELFAGYTRKYSMAVWTGYSNRLTPLVGNGLTVAAKVYRSMMTY
                     LSEGSNPEDWNIPEGLYRNGEFVFKNGARSTWSSPAPQQPPSTESSSSSSDSSTSQSS
                     STTPSTNNSTTTNPNNNTQQSNTTPDQQNQNPQPAQP"
     gene            complement(71096..76399)
                     /locus_tag="VQ540_000332"
     CDS             complement(71096..76399)
                     /locus_tag="VQ540_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001032503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK signal domain/LPXTG anchor domain surface
                     protein"
                     /protein_id="HET2544202.1"
                     /translation="MNKGLFEKRCKYSIRKFSLGVASVMIGAAFFGTSPVLADSVQSG
                     STANLPADLATALATANENDGRDFEAPKVGEDQGSPEVTDGPKTEEELLALEKEKPAE
                     EKPKEDKPAAAKPETPKTVTPEWQTVEKKEQQGTVTIREEKGVRYNQLFSTAQNDNAG
                     KPALFEKKGLTVDANGNATVDLTFKEDSEKGKSRFGVFLKFKDTNNNVFVGYDKDGWF
                     WEYKTPGNSTWYKGNRVVAPEPGSVNRLSITLKSDGQLNASNNDVNLFDTVTLPGAVN
                     DNLKNEKKILLKAGTYGNDRTVVSVKTDNQEGVKADDTPAQKETGPVVDDSKVTYDTI
                     QSKVLKAVIDQAFPRVKEYSLNGHTLPGQVQQFNQVFINNHRITPEVTYKKINETTAE
                     YLMKLRDDAHLINAEMTVRLQVVDNQLHFDVTKIVNHNQVTPGQKIDDERKLLSSISF
                     LGNALVSVSSDQTGAKFDGATMSNNTHVSGDDHIDVTNPMKDLAKGYMYGFVSTDKLA
                     AGVWSNSQNSYGGGSNDWTRLTAYKETVGNANYVGIHSSEWQWEKAYKGIVFPEYTKE
                     LPSAKVVITEDANADKKVDWQDGAIAYRSIMNNPQGWEKVKDITAYRIAMNFGSQAQN
                     PFLMTLDGIKKINLHTDGLGQGVFLKGYGSEGHDSGHLNYADIGKRIGGVEDFKTLIE
                     KAKKYGAHLGIHVNASETYPESKYFNEKILRKNPDGSYSYGWNWLDQGINIDAAYDLA
                     HGRLARWEDLKKKLGDGLDFIYVDVWGNGQSGDNGAWATHVLAKEINKQGWRFAIEWG
                     HGGEYDSTFHHWAADLTYGGYTNKGINSAITRFIRNHQKDAWVGDYRSYGGAANYPLL
                     GGYSMKDFEGWQGRSDYNGYVTNLFAHDVMTKYFQHFTVSKWENGTPVTMTDNGSTYK
                     WTPEMRVELVDADNNKVVVTRKSNDVNSPQYRERTVTLNGRVIQDGSAYLTPWNWDAN
                     GKKLSTDKEKMYYFNTQAGATTWTLPSDWAKSKVYLYKLTDQGKTEEQELTVKDGKIT
                     LDLLANQPYVLYRSKQTNPEMSWSEGMHIYDQGFNSGTLKHWTISGDASKAEIVKSQG
                     ANDMLRIQGNKEKVSLTQKLTGLKPNTKYAVYVGVDNRSNAKASITVNTGEKEVTTYT
                     NKSLALNYVKAYAHNTRRNNATVNDTSYFQNMYAFFTTGSDVSNVTLTLSREAGDQAT
                     YFDEIRTFENNSSMYGDKHDTGQGTFKQDFENVAQGIFPFVVGGVEGVEDNRTHLSEK
                     HDPYTQRGWNGKKVDDVIEGNWSLKTNGLVSRRNLVYQTIPQNFRFEAGKTYRVTFEY
                     EAGSDNTYAFVVGKGEFQSGRRGTQASNLEMHELPNTWTDSKKAKKATFLVTGAETGD
                     TWVGIYSTGNASNTRGDSGGNANFRGYNDFMMDNLQIEEITLTGKMLTENALKNYLPT
                     VAMTNYTKESMDALKEAVFNLSQADDDISVEEARAEIAKIEALKNALVQKKTALVADD
                     FASLTAPAQAQEGLANAFDGNLSSLWHTSWNGGDVGKPATMVLKEPTEITGLRYVPRG
                     SGSNGNLRDVKLVVTDESGKEHTFTATDWPDNNKPKDIDFGKTIKAKKIVLTGTKTYG
                     DGGDKYQSAAELIFTRPQVAETPLDLSGYEAALAKAQKLTDKDNQEEVASVQASMKYA
                     TDNHLLTERMVEYFADYLNQLKDSATKPDAPTVEKPEFKLSSLVSDQGKTPDYKQEIA
                     RPETPEQILPATGESQSDTALFLASVSLALSALFVVKTKKD"
     gene            complement(76700..78682)
                     /locus_tag="VQ540_000333"
     CDS             complement(76700..78682)
                     /locus_tag="VQ540_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HET2544203.1"
                     /translation="MKSSKLLALAGVTLLAATTLAACSGSGSSTKGEKTFSYIYETDP
                     DNLNYLTTAKAATANITSNVVDGLLENDRYGNFVPSMAEDWSVSKDGLTYTYTIRKDA
                     KWYTSEGEEYAAVKAQDFVTGLKYAADKKSDALYLVQESIKGLDAYVKGEIKDFSQVG
                     IKALDDQTVQYTLNKPESFWNSKTTMGVLAPVNEEFLNSKGDDFAKATDPSSLLYNGP
                     YLLKSIVTKSSVEFAKNPNYWDKDNVHVDKVKLSFWDGQDTSKPAENFKDGSLTAARL
                     YPTSASFAELEKSMKDNIVYTQQGSITYLVGTNIDRQSYKYTSKTSDEQKASTKKALL
                     NKDFRQAIAFGFDRTAYASQLNGQTGASKILRNIFVPPTFVQADGKNFGDMVKEKLVT
                     YGDEWKDVNLADSQDGLYNPEKAKAEFAKAKSALQAEGVTFPIHLDMPVDQTATTKVQ
                     RVQSMKQSLEATLGADNVIIDIQQLQKDEVNNITYFAENAAGEDWDLSDNVGWGPDFA
                     DPSTYLDIIKPSVGESTKTYLGFDSGEDNVAAKKVGLYDYEKLVTEAGDEATDVAKRY
                     DKYAAAQAWLTDSALIIPTTSRTGRPILSKMVPFTIPFALSGNKGTSEPVLYKYLELQ
                     DKAVTVDEYQKAQEKWMKEKEESNKKAQEDLAKHVK"
BASE COUNT        22926 a        17949 c        14578 g        23356 t
ORIGIN      
        1 ttatagtttg tcttttttct atcttccatt atatcatact ttttcagtct atggtagctc
       61 tctttaaaag gcaccgatac tgccgccacc tccgcctcca gagaagccac caccagaact
      121 tccacttcca gaagatacag agtaggtgct tgctgtattt gcgacactag cataatggct
      181 catttgcgcg cttgaatgat aaaacagact gtgccagcca taagctacat agagattgat
      241 atctggattt tccacttgaa tctgatgaac cttcatcaaa tgactaacct tgtccgcata
      301 gccaaataag gtcgcataga ccaagaggcg attccagacc acaatacttt ccagttcagc
      361 ctgatccaat cgtgcaatct cacgcaacat attttcaaaa ctggtccaga gatagtagac
      421 ctcagctccc gcttcattta gaacaccatc acgattatct agtcgaagct tccaataata
      481 gaaaacagac aaaactaacc ctagaaaacc aagtattggc aaagggaggt aaagatagcc
      541 atgaacgtct aaactgtaca agaacaaacc aaatccgata aataggggca ggatagtcaa
      601 ggcacccata cccacttgca aggccttttc cccaccagtt aaaggacgat aataatctgg
      661 gagcccccag aaggaaactc gttttctcac tccttcttgc atctggttca atacctcttc
      721 aaaagaagat ttgagttgaa gccctcttgc ttgaatccgt ttttcatcag aaactttggc
      781 tctacgataa agactatcag ataccttgta atccgcaaac aaattggaaa gagtttcttc
      841 ttttttacct gaaaaagcta gatttaggca gtctttctca aagcttgaca aaccatcttc
      901 ttttactagc ctcaaaccaa ctgcatctcc ttctgaaatg atagagacat tcccacggtc
      961 tatcacatct agcaaggtag cttgaataag ttgatcaaag gtgaattttc cagctccctt
     1021 gaccaaggga ctcacttcct ccaaggaggt cgagtagact gcttctgata aaaccatagg
     1081 ctctaattcc attggtggtt catagagacg atgatttttg gcatatttga ctgaaggagt
     1141 ggtctttctt ctataaataa aatagaagca gacactcaat aacaaggaga tagaaaggat
     1201 cgaagggagg acccaagtaa caagttgttt actctgatct ttttctctaa caatcgagtc
     1261 ttctatctta ttaaactctt ctaaacgatt ccctttcaat ccctgatccc tagcgctagc
     1321 aaaatcggtc cgaggccaat aggcatgcaa ctcaactcca cgcttagccg gaagattgtc
     1381 taaacggata gtataatcaa ggttactctt ttcaatcgtt ccctctctaa aaagtttccc
     1441 tgtatggaaa aagagttttt cagctccctt gtctcccctt acatgaaatt caaacttttc
     1501 aatagactct gaactatctg tcagaggttg ccaatttaat tcagcgatat catcataaag
     1561 gaaaagtaaa ttttttaagt tccagacgag gtcaacttca actatgtcgc cctcctgacc
     1621 tggattatag actctcacag tataaccatc cgcttcttct gttacttcgc tagtcacatc
     1681 tgctagttct gcaccgtttt tcgcggcctg aacctttgga tgagggtcaa tgtcaaaccc
     1741 gctaggcatc ttaccagcac gtccaagtcc cacgatttgt cccttaaagt cctcctcaaa
     1801 ctggtaaact atcttctgtc taaactctgc cgtattatct gcatgaatat acaaatcccc
     1861 ttgataagag tttatcttga aatcaatggc aaaaacagag agtggaagaa ggcaaaacaa
     1921 gcctaacacc agtaagaaaa aagttttttt catcaactaa gccccctttt tatctttctt
     1981 atcattatag cattttttcg taagtaaagg cttacttatg ttgaaaaatt acgcattttt
     2041 cgataaaata ggagacagtt attttttaat agatcagaat aggagaaatc atgagaaaaa
     2101 tatacttatc tattttcaca agtctcttgc tgatgctagg acttgtcaat gttgctcaag
     2161 ccgatgaata tttacgcatc gggatggaag cagcatatgc tccctttaac tggacccagg
     2221 atgatgatag caacggagct gtcaaaatcg atgggaccaa tcagtatgcc aacggatacg
     2281 atgttcaaat cgccaagaaa atcgctaagg acttaggtaa aaaacctttg gttgttaaaa
     2341 ccaagtggga aggtctagtc cctgccctta cttctggtaa gattgacatg attatcgcag
     2401 gtatgagtcc aactgcagaa cgcaaacaag aaattgcctt ttcgagcagt tactacacta
     2461 gcgaaccagt tttgcttgtc aaaaaagatt ctgcctacgc aagtgctaaa tctttggatg
     2521 actttaacgg tgcaaaaatc acttctcaac aaggggtcta cctctacgac ttgattgcac
     2581 aaatcccagg tgctaaaaaa gaaacagcca tgggagactt cgctcaaatg cgacaagctc
     2641 ttgaggctgg tgtcattgat gcttatgttt ctgaacgtcc agaagcactg actgctgaag
     2701 ctgcgaactc taagttcaag atgattcaag tagaacctgg tttcaaaact ggggaagaag
     2761 atacagctat cgctatcggg cttcgtaaaa atgacaatcg tattagccaa atcaatgcca
     2821 gcattgaaac catttcaaaa gatgaccaag ttgccttgat ggatcgtatg atcaaggaac
     2881 aacctgccga agctacaaca actgaagaga ctagcagtag tttctttagc caagtcgcta
     2941 aaattctttc tgaaaactgg caacaactct tgcgtggtgc tggtatcact cttttaatct
     3001 ctatcgtcgg aaccatcata ggtctcatta ttggacttgc cattggtgtc ttccgtactg
     3061 ctcctctctc tgaaaacaaa gccatttatg gccttcaaaa actagtcggc tgggttctca
     3121 atgtctacat tgaaattttc cgtggtacgc caatgattgt tcaatcgatg gttatctact
     3181 atggaactgc ccaagctttc ggtatcaacc ttgaccgtac actagctgct atcttcatcg
     3241 tttcaatcaa taccggtgcc tacatgactg aaattgtccg tggtggtatc ctggcagttg
     3301 acaagggaca atttgaagct gcgactgctc ttggtatgac tcataaccaa accatgtgta
     3361 agattgtcct acctcaggtt gtccgcaata tcctaccagc aactggtaat gaatttgtca
     3421 tcaatatcaa agatacatct gtattgaacg ttatctctgt tgtcgaactt tatttctcag
     3481 gaaataccgt ggcaacacaa acctatcaat acttccagac atttacaatc atcgccgtga
     3541 tttactttgt cctcaccttc accgtaacac gtatcctacg ctttatcgag cgcagaatgg
     3601 acatggatac ctacactaca ggtgctaacc aaatgcaaac ggaggatttg aaataatgac
     3661 acaagcaatc cttgaaatta aacacctcaa aaaatcctat ggacaaaacg aagtgctaaa
     3721 agacatttct ctcactgtcc acaagggaga agttatttct atcatcggaa gctctggaag
     3781 tgggaaatca accttcctac gctccattaa cctacttgaa acgccaactg atggacaaat
     3841 cctttatcat ggacaaaacg tcctcgaaaa aggctatgac ctcacgcaat accgtgaaaa
     3901 gttagggatg gttttccaat cctttaacct ctttgaaaat ctcaacgttc ttgaaaacac
     3961 aatcgtcgct cagacaactg tccttaaacg cgaacgcaca gaagctgaag aaattgccaa
     4021 agaaaacctg gaaaaggtcg gcatgggaga acgctactgg caagcgagac ccaaacaact
     4081 ctcaggtggt caaaaacaac gtgtggccat cgctcgtgcc ctttcaatga atcctgacgc
     4141 cattctcttt gatgaaccaa catcagctct cgatccagaa atggttggag aggtcctcaa
     4201 aatcatgcaa gatctggctc aggaaggctt gaccatgatt gtcgtaaccc atgaaatgga
     4261 atttgcccgt gatgtctctc accgtgttat ctttatggat aagggtgtga ttgctgaaga
     4321 aggtaaacca gaagacctct tcactaatcc taaagaagac cgtacaaaag aatttcttca
     4381 acgttatctc atactcaatg aaaatcaaag agcaaactag gcagctagcc gcaggttgct
     4441 caaaacactg ttttgaggtt gcagatagag ctgacgtggt ttgaagagat tttcgaagag
     4501 tatcaaataa aaagaaaagg ctgcatcaac cgtgcagtct ttttgctgtc ctcaaaatga
     4561 aaaggcagat tctctatctc tactacttga aggtcaagaa tccaccgtta tccaaagatt
     4621 aatcttcaaa tttttcatga tttttttcat agaaatcaat taagcctagg gctgtttcaa
     4681 atgaaatatt ttttactttt gcacgaccct gcgccagagc aatgatagac atttcacgcg
     4741 cattcgtttc tttagagata cggtagcctg tgattttctt atcacgaacc cagccaacaa
     4801 ctgattctac tttttcaaag tttgacttag ccatgttttt ctcctatttt cttctttata
     4861 atatttaatt gtatacgttt ttactacttt tgtcaataaa aaaaacatat attcaacgaa
     4921 aataattagt tcagaatttt cttacttcct ttttaaatcc gataatatat aggttttgct
     4981 agcctctaca ccataaatat ttgctaataa aaatactgta ttattaccct cttaaggtgc
     5041 aaaattattc aagttcttaa aaaatgcttc tctatttccg taagatagct tatttcttcg
     5101 atttaagaac tgaagatgat agttctaacc tttagaaatc caagccttct ctagctcaaa
     5161 aactcctatc tttcttcctc aataaatcat ctgagagata ggtattcctt atatccttca
     5221 aattcatcac tcctttggat attgaggtgc tagcctagaa gcagacaccc gattatctaa
     5281 accatcctta atagagatga caagacagat aagctcagtt aattacttat atatcttttt
     5341 aatatggtat atttgtcaac aaaaagaaat caaatcatac cttatactca atgaaaatca
     5401 aagagcaaac taggaagcta gccgcaaatt gctcaaaaca ctgttttgag gtttcagata
     5461 gagctaacgt ggtttgaaga gattttcgaa gagtattaaa gacagtatga ctatgcttgt
     5521 caatagatag gaaatcaaaa tgaaggatgg aaatctgagc caaacatcat aagtgctata
     5581 atgaacagaa gtaagaattg cacgataagt tttctaaaac cataggaatc gtcccctttc
     5641 ttcatcttca ttatagcaca tatacatcag ttgtacaaat aatatgatat ttttttatta
     5701 gtcctcagac aagcatatta taaagcgttt cattaccatt taagttaata taagctggat
     5761 caaaaccttc cattctacgg atcaaacctg cataatcatg cttatctgcc aaagcgatcc
     5821 caatcaatac tgggcctgtt cccttgctag ctcgtttgat atactcaaaa cgtgtgatat
     5881 catcatttgg ccccaggata tcatttacaa actcacgcaa agctcctgga cgctgtggga
     5941 aattgaccac aaagtaatgt ttgataccat cataaatcaa ggcacgctct tccatttctg
     6001 gcatacggtt gatatcatta tttcctccag aaatgataca acaaatggtt ttccccttaa
     6061 tatattcagc taaaacctct aaagaggcga tactagccgc tccagcaggt tctgcgacta
     6121 tcccttgctt agagtaaagg tcaatcaagg tttcagaaat caatccctca tcgacaccta
     6181 ccaaagtttg aatatgttga cgagttgctt cataggtcaa ctgacctacc ttttgcacag
     6241 caatcccatc cgcaaattta tcaatttcct tgagtttgac tggacctcca gcctcaaagg
     6301 cagctttcat ggaacgcgct ccattcgcct ctactccgat aacctcaatc tctggacttg
     6361 tttccttgat ataggtagaa accccggcaa tgagaccgcc accaccaaca ggaaccaaga
     6421 cagcatcaaa atcaatcgat tcttttcgag cttcttctaa aatctcataa gcaactgttc
     6481 cttgacctgc ttgaacatga gcatcatcaa aaggatcaat aaaggtacga ttttcagaga
     6541 ctgtaaattc ttgagctgct ttggctgagg catcaaaggt atctccaact agtttaatag
     6601 ttacaaaatc cccaccaaaa aagcgaacct gaccaatctt ttgttgtggc gtagtaatag
     6661 gcataaagat agtagcagga attttcattt cattacaagt ataggctact ccctgcgcat
     6721 gatttcccgc agaagcgcag actaccccac gttcacgttc ttccttgctg agctgggaaa
     6781 tggcataata ggcaccacga attttaaagg agcgaacacg ctgggcattt tcttttttca
     6841 aataaatctt agcaccatac ttctccgata aataatgatc gtaatccagt ggagtattca
     6901 caaccacacc gttcaagacc ttgtgagcct tgattatatc ttttgaactt aacatataaa
     6961 acctcttttt ctataaaaaa cagtcactaa tgactgtttt ttagttattc atctccgaaa
     7021 acttcagtaa cactttcatg gtatttatga gccatacgaa tcgaaaactc tttaggaagt
     7081 tcataacgat ttgtggaaat ccaatcatat aaccattcta ccaaactttc ttcactatca
     7141 ttacgatgga agataaaata gtttaaaatt tctttatatt ctacatcatt caaatccaac
     7201 gtgtctacaa attgactacg aggaacaaaa ttagaatcta attttcttag ttgatctgtc
     7261 aattctccca attgtaaatc caactgaaaa aatagttttt gcagttgcct atcagtttca
     7321 tcacatcctg tcttgataga aaacaaattg gtaatattca tatgatttca acccctaaat
     7381 aagtacatct aatatcccac gaatagctga agctaaagtt ttcgcagtcc agtcatttaa
     7441 acccgattct ttcaatccag atgcaataat ttgctctatt tgatataaac cgccatctat
     7501 cgtctcattt attctgcgaa gaggaccttc aatataggat aaagcttctc cgaatctaac
     7561 agctgattta ggtcctaatg atttaccaac tatatttgtt aatgtttttt atttctcaaa
     7621 atccatttcg ctatataacg agcagattta gtcgcaccag ctctctcaaa cggagaatga
     7681 atttcaagac cttcttctct agctatttgt gccaatttga agaattgttc aaaggtcata
     7741 tgcaacctac catcttcaaa attagcatca tcataaatgt taattacagc attttcatca
     7801 tacgaccaat ctgctttatt ttggtctgct agcactatta ccgacggtgt aattacatta
     7861 tacaactaga accaataata acgatgcaat ttttctcata atctttttca taaaatcatc
     7921 tccagcgcta tatatttcta attagttata gattttgaat gcatcatcgt cgtttttacc
     7981 aacaaatggc attgctttac gcaattctgc accaactttt tcaatttcaa ggttagctgc
     8041 ttgttcacgg taagcagtca attttggacg tccagcttta tagtcattta caaagtcatt
     8101 tgcaaattta ccattttgga tgtctgccaa gacagccttc atattttctt taacttgttc
     8161 agtgattaca cgtggacctg atacatagtc accgtattca gcagtgtttg aaatagattg
     8221 acgcattttc ttgaatccac cttcgtagat caagtcaacg atcaatttca tttcgtgaag
     8281 aacttcaaag taagccaatt ctggagcgta acctgcttct gtcaagactt cgaaacctgc
     8341 ttcgataagg gcagtcaaac caccacaaag tacagcttgt tcaccaaaca aatcttcttc
     8401 agtttcttct ttgtaagttg tttcaagaag acctacacga gccgctccaa cacctttaca
     8461 ccagtccata gcaatgtttt tagcatttcc tgttgcatct tggtatactg cataaagagc
     8521 tggaacacca aatccttctt cgtaagtacg acgtaccaag tgtcccggtc ctttaggagc
     8581 acacatgaag acatctacat ccgcaggaac tttgataaat tcaaagtgga tgttgaaacc
     8641 atgggcaaat ccaactgcgt ttccagcttc caagtttgga gcgatttctg cttcgtacaa
     8701 ttcttgttga atttcgtctg gcgccaagat catgataaca tcagccaact tagtagcttc
     8761 tactactgtg taagtatcaa atccatcttc ttttgcttta tcaaaagatt tacctggacg
     8821 tacaccgata ataacgtcac gacctgaatc acgcaagttt tgagcatgcg catgtccttg
     8881 tgaaccataa ccgataacgg cgattttttt accgtcaagt gctgctactt taacatcttt
     8941 ttcatattcc atttgaactg tcatagcttt tctctctttt ctattattta ttgcctttta
     9001 ggctggttta ataaatttaa gttggatttt taatcgcggg taaatccagt tgcacccgtt
     9061 cgagcaatat tgcgaatacc gtatgggcga atgactcgca atagggcttc gctcttttct
     9121 gcatttcccg tcatctgaat ggtaatcgag cttggcgcta cgtctaccac tgttgcacgg
     9181 aaaggttgaa taatcgctaa aatctcagct ctcttctcag ctggcgctga catcttaacc
     9241 aaaatcacct cgcgctccaa atgaggcttg tctgtaatat ctcgaatgcg aatcacatca
     9301 atctgacgat tgagctgttt gatgatttgc tccacttcat catgagaagc aacatcaata
     9361 ataatagtga tacgcgatac attcggatct tctgttgctc caacagagat gctttcaata
     9421 ttaacctgac gacgagatag gacacctgta aagcgattga ggactcctga acgattttgt
     9481 agttttgctg ttaacattct acgcatggaa ctgcaccccc aacatctcat gattactctt
     9541 accagccggt accattggta acacctgttc cttacgagaa atatctacct caattagcat
     9601 aggaacatcc tcagtgatga cttcaaggtc ttgagccaag gtctcaggat tgtcaaactt
     9661 atagttttta ataccataag cctgcgccat caattggaaa tcaggaaggg tatcaaagac
     9721 cgactctgat gttctgcctt catagaagga ttcctgccac tggcgaacca ttccaagtga
     9781 atgattgttc agcataacca ccttgattgg caccttgtaa atattcaaaa tagccaactc
     9841 ctggttggtc atttggaaac caccatcccc aacaaacaag actacttcct tatctgggtt
     9901 agcaatttta gcaccgattg ctgctggaat tccaaagccc attgttccca aaccacctga
     9961 agtcactaac tgacgctcat tttggtaggg ataatactga gctgtccaca tttggtgttg
    10021 accaacgtct gttaccacaa tggcatctcc attcgtcaat tcaccaattc gttcaataac
    10081 tgcttgcggt tgaaccacac gctctttctt gtcataagaa cgaacacgat tcttgtcttt
    10141 agtgactttc tcaatccact tttcagtatt gttgtgaact gttggttctg ctagcaacat
    10201 ttgcaaggcc ttcttagcat ctccaactac aggaatgtct gcactgataa tcttgccaat
    10261 ctcagctggg tcaatatcaa tgtgggcaac cttagcattc ttagcgaaag tcttaggatt
    10321 ccccgtcaaa cggtcatcga aacgagaacc aatactaatc ataaagtccg cttccgtcat
    10381 ggcaatattt gctgcgaatg acccgtgcat gcctcccatt ccaagaaaga gtgggtgact
    10441 cgttgcaatc gttccttgtc ccaaaagact ggttaccact ggaatttgat agcgttctgc
    10501 aaattcattt agttccgtag cagcctcagc ataactaatt ccaccaccag ctaacaagac
    10561 tggcttttta gccttggaca attgcttcaa gattttcttg atttgcatat cattcggctc
    10621 aagagtcggc tgataacttg gtaaattcac ttctggtgaa taaatgaagt ctgtttctaa
    10681 agcagatatg tcttttggta ggtcaattac aactggccct ggacggcctg tagttgcgat
    10741 atggacagct tccgtaatga tacgcggaat atcagctgtc tcacgaactt ggtaattgta
    10801 cttagtgatt ggcatggtaa ttcctacgat gtctgcctcc tgaaaggcat ccttcccaat
    10861 ccctgctcgc gccacctgac ctgtaaagac caaaagggga acgctatcgc tcatagcatc
    10921 cgcaatccct gtaatggcat ttgttgctcc tggtccacta gtgacgacgg caacacccaa
    10981 ctttccagtt gatttggcat aaccttcagc ttcatgcaaa caaccttgct catggcgccc
    11041 tagaatgtgg cgaatgcctt taaaattata tatcgcatca taaaaaggca aaaccgcacc
    11101 accaggataa ccaaagatgg tatcaactcc taaatcacga agtgtttcca aaactaggtc
    11161 cgaccccgtc ttaggagatt ctaaactgat tttctccatt gttccccttt ctttcctctt
    11221 aaaaataact tgttactatc ataccatttt ttcaaaattt ttcaagataa aagaagaaat
    11281 tttctgaatt ttctatttta acgtttattt atgaatgtta tttttgtttt tattaaaaag
    11341 ataccgattt catttactaa aaaagaaaaa agaactgatt tctcagtcct tcattaatct
    11401 tattccacac taaataggta tgggtaaaca ggttgttgac cttggtgaat ctcgacttca
    11461 acgtcttcga attcttctac gatttcttga gcgatttcat tggcaagttc ttcgcttccg
    11521 tcttcaccga catagaaggt tacgatttca ctatcttcat ccaacatatg tttcaaggtt
    11581 tcagtcaatg tttggtgcat atcagggttt gacacaagaa tttttccatc caccatacct
    11641 agattatcgt tttcatggat ttctaagcca tcgatcgttg tatcacgcac ggctgttgtg
    11701 acgcttccgc taacgacatc gctaagagca gctgtcatac gctcttggtt ttcttcaatg
    11761 gacttgcttg gatcaaaggc aagaagactt gtcatacctt gaggaagagt gcgagcctct
    11821 accactactg ctggttgctc caaaacttct gccgcagatt gagctgccat gaagatgttc
    11881 ttgttgtttg gcaagaagat gatgttacgg gcattgacct gttcaacagc cttgataaag
    11941 tcttctgttg aagggttcat ggtttgaccg ccttcgataa cataatccac gccttgagaa
    12001 cagaagatat ctgctagacc tttaccagcc accacagcaa tcaaagcata ctctttttct
    12061 tcagccgact tgataacttg agtagcttct ttctcaacct gtgcttcgtg ttggttacgc
    12121 atattgtcaa cttttacctt gaccaagcta ccatatttga gaccttcttg cataacaagt
    12181 cctggatctt ctgtatgaac atggactttg acaatttcat catcgttaac aacgaggaga
    12241 gaatccccaa gctcatccaa gtagttacgg aattcatcgt agtcaaaatc tttagcatag
    12301 gttggacctt gcttaagagc taccatgatt tcagtacagt aaccaaacgt gatgtcctca
    12361 gtcgctacgt gaccagctac agacttatga tgctctacat tgatcatctc actcatgttg
    12421 gcaggagtcg ctacaaagtc ctcagatgca atatattcgc cagtaagggc tgaaaggaaa
    12481 ccttcgtaga tgaagaccaa tccttgacca cctgagtcca caacgccaac ttctttcaat
    12541 actggaagca tgtctggtgt tttagctaga gctgttttag caccttccaa ggctgcgcgc
    12601 atgacttcaa cagtgtcatc tgtttgctca gcttttttct tagcaccgat agcagctcca
    12661 cgagaaactg tcaaaatcgt tccttcaaca ggtttcatca ctgccttata ggcaacttcc
    12721 acacctgatt ggaaggccag agccaagtct tgacctgtta actcgtcttt atccttgata
    12781 gcttgggaaa atccacggaa aagctgagac gtaatcactc ctgagttccc acgcgcaccc
    12841 atcaaaagcc ctttggcaag aatgctcgct acttctccaa ctgtagaagc tggcttgtct
    12901 gcaacttctt tagcaccatt ttcaatggtc attcccatat ttgtcccagt atctccatct
    12961 ggaactggaa agacgtttaa tgaattgaca tattcagctt gcttattcaa gcgagttgat
    13021 gcagcctgca ccatttcttg aaataagcta gtagtaattt ttgacacggt tattctccta
    13081 caactttgat attttgaatg tagacattta cagtctgagc agtaattcca agctggtttt
    13141 ccaagctaaa ggcaacacgc tcttgaatgt tttttgacac ttcactaatc tttgttccgt
    13201 agcttaacac ggtatataca tcaactgcaa tactgccatc ttcggctgcc tttacgacga
    13261 cacctttaga ataattttcc ttacctagca gggcttggaa attatctttg agggcatttt
    13321 tactagccat accgaccaca ccaaaaatct cagttgctgc tccacctacg acggttgcaa
    13381 tcacttcatc tgttagttcg atttgaccat cttttgtatt aatttttaca gtcatccttt
    13441 ttacctcaac tagttgatac tctattttat catatttcag cccaagtgta aaagcagaat
    13501 gatgtatcag cggatattta ctctattttt caaacgatgt tatacccaca ataaaagaaa
    13561 aaagacccta aggtctcctt tgcttttatt attaaacgcg ttcaacttta cctgatttca
    13621 aagcacgagc tgaagcccaa acttttttag gtttaccatc gataagaaca gtaacttttt
    13681 gaaggtttgg ttttacggca cgttttgttt ggttcatcgc gtgtgaacgg ttgtttcctg
    13741 atacagtctt acgacctgta aagtaacata ctttagccat tgtgttttcc tcctattaga
    13801 tctaatatag cggatgtgct agcaccacat accgtactat gttatcacac tttcttgttt
    13861 tttgcaaggg aattggaaga ttttttattt gtgtcttaaa tcaggtcttg cgtgacattt
    13921 tctgctctcc acatgccatc gttgattaac agaacaccag aattaaaatt atgtgtataa
    13981 aaatcatctc taactgcagc taagggtata gccgtcaagt ccaaatccca cagctcatct
    14041 atcgattttc ttacaacaat atctgaatcc aaatacagta cacgagactc gcttacatac
    14101 tttggaataa aatacctaaa aaagccgcat atgaaagtcc ctcaaagggg agacgataac
    14161 ctttcagaat attactgtca atctaaacat tcacaatctc actattcaaa gtctctagtc
    14221 ttttttccat caattggaac cattctcgcg gaaggtcatc attaaaaaca taaaacttaa
    14281 gattataatg atgaacacaa agagatttta ttgttgtttc aactttatcc atataagcat
    14341 tatctgcacc taagacaatc gcttttttct cttttttctc ttctttcact ttttatctca
    14401 tttcttttta ttcccatcat atgtttctac gtaaccatta ttttcgccta ttcgttcgta
    14461 aaaccatacc agtggagatt ttagatgaag tcccattacg gtttacaatt tttacattac
    14521 gacacggagt tttacaaatc gatttcattt gccaaacgta gttagtgagg cagttagcta
    14581 gttcgccaaa tagcgactag cgtccaacaa tttggaactt tagttccaat tgttggtact
    14641 gagtcacatc ttctcctcta actctacgtc tggatacttg tcagcaaacc agcggagggc
    14701 aaagtcattt tcaaagagaa agactggttg gtcaaaacgg tctttggcta agatattgcg
    14761 acttgacgac atccgttcat ccaagtcctc aggcttgatc caacgaacgg tctttttacc
    14821 cattgggttc ataactactt ctgcattgta ctcgccttcc atgcggtgtt taaagacttc
    14881 aaactggagt tgacctacag cgcctagcat gtactcacct gtttggtaat tcttataaag
    14941 ctgaacggct ccttcttgca ccaattgctc aatccccttg tggaaggatt tttgcttcat
    15001 aacattctta gcagaaactt tcatgaaaat ttcaggagta aaggttggca gtggttcaaa
    15061 ttcaaacttg tttttaccaa ctgtcaaggt atccccaact tgataagtac cggtatcgta
    15121 aaccccgata atatcacctg ccacggcatt gatcacattc tcacgacttt ccgccataaa
    15181 ctgggtaaca ttagatagtt tggccccctt accagtacga gggagattga cactcatgcc
    15241 acgctcaaat tcgcctgata cgatacggac aaaggcaata cggtcacggt gacgaggatc
    15301 catgttggct tggattttaa agacaaagcc tgagaaatcc ttgtcataag gatccacaat
    15361 ttcaccgtct gttttcttgt gaccatgtgg ttctggagca aacttgagga agatttcaag
    15421 gaaggtctgc acaccaaagt ttgtcagggc tgaaccgaaa aagacaggcg tcaattctcc
    15481 agccagaata gcttcctctg aaaactcatt cccagcttca tttaaaagct caatgtcatc
    15541 cttgacttgc tcgtagaaag gattgctacc aaagagtttg tccccgtctt ctagactggc
    15601 aaaacgctca tcccctttgt aaagctctaa acgttggtta tagaggtcat acaagccctc
    15661 aaaggctttc cccatcccga taggccagtt catagggtag ctagcaatgc ccaagatttc
    15721 ttccaattct tgcaagagat ccaaaggctc acgaccgtca cggtccagct tgttcataaa
    15781 ggtaaaaact ggaatgccac gatgtttcac aacctcaaac aatttcttgg tttgagcctc
    15841 gatccccttg gcagagtcca cgaccatgac cgcagcatcc accgccatca aggtacgata
    15901 ggtatcttct gagaagtcct cgtgccctgg cgtgtctaag atattcacgc gcttgccgtc
    15961 gtagtcaaat tgcataacag atgaagtaac agaaatccca cgttgcttct cgatatccat
    16021 ccagtcagat ttagcaaaag tccctgtttt cttccctttt accgtaccag cctcacgaat
    16081 ctcaccccca aagtagagta actgctcagt gatggttgtt ttccccgcgt ccgggtggga
    16141 gataatggca aaggtacgac gtttcttaat ttcttcttga atattcataa gttctctttc
    16201 tttgattctc tatttttctt gtttcaatag ctgagaatga tttttacatt ggattttacc
    16261 attcctttca acattccatt atatcggatt ttagcatttt tttcaatttc tatttctttt
    16321 cacttccccc tcccttattt ataggaaaat atggtaaaat agaacagact aaaaatcatc
    16381 atttcacgaa aggatgcaag atgaaaatta cgcaagaaga ggtaacacac gttgccaatc
    16441 tttcaaaatt aagattctct gaagaagaaa ctgctgcctt tgcgaccacc ttgtctaaga
    16501 ttgttgacat ggttgaattg ctgggcgaag ttgacacaac tggtgtcgca cctactacga
    16561 ctatggctga ccgcaagact gtactccgcc ctgatgtggc cgaagaagga acagaccgtg
    16621 atcgcttgtt taaaaacgta cctgaacaag acaactacta tatcaaggtg ccagctatcc
    16681 tagacgatgg aggagatgcc taatgacttt taacaataaa actattgaag agttgcacaa
    16741 tctccttgtc tctaaggaaa tttctgcaac agaattgacc caagcaacac ttgaaaatat
    16801 caagtctcgt gaggaagccc tcaattcatt tgtcaccatc gctgaggagc aagctcttgt
    16861 tcaagctaaa gccattgatg aagctggaat tgatgctaac aatgtccttt caggaattcc
    16921 acttgctgtt aaggataaca tctctacaga cggtattctc acaactgctg cctcaaaaat
    16981 gctctacaac tatgagccaa tctttgatgc gacagctgtt gccaatgcaa aaaccaaagg
    17041 catgattgtc gttggaaaga ccaacatgga cgaatttgct atgggtggtt ccggtgaaac
    17101 ttcacactac ggagcaacta aaaacgcttg ggaccacagc aaggttcctg gtgggtcatc
    17161 aagtggttct gccgcagctg tagcctcagg acaagttcgc ttgtcacttg gttctgatac
    17221 tggtggttcc atccgccaac ctgctgcctt caacggaatc gttggtctca aaccaaccta
    17281 cggaacagtt tcacgtttcg gtctcattgc ctttggtagc tcattagacc agattggacc
    17341 ttttgctcct actgttaagg aaaatgccct cttgctcaac gctattgcca gcgaagatac
    17401 taaagactct acttctgctc ctgtccgcat cgccgacttt acttcaaaaa tcggccaaga
    17461 cattaagggc atgaaaattg ctttgcctaa ggaataccta ggcgaaggaa ttgatccaga
    17521 ggttaaggaa acaatcttaa acgcggccaa acactttgaa aaattgggtg ctatcgtcga
    17581 agaagtcagc cttcctcact ctaaatacgg tgttgccgtt tattacatca tcgcttcatc
    17641 agaagcttca tcaaacttgc aacgttttga cggtatccgt tacggctacc gcgcagaaga
    17701 tgcgactaat cttgatgaaa tctatgtaaa cagccgtagc caaggttttg gtgaagaagt
    17761 gaagcgccgt atcatgctgg gtactttcag tctttcatca ggttactacg atgcctacta
    17821 caagaaggct ggacaggtcc gtacacttat cattcaagat ttcgaaaaag tcttcgcgga
    17881 ttacgatttg attttgggtc caactgctcc aagtgttgcc tatgacttgg attctctcaa
    17941 ccatgaccca gttgccatgt acttagccga cctcttgacc atacctgtaa acttggcagg
    18001 actgcctgga atttcgattc ctgctggatt ctctcaaggt ctacctgtcg gactccaatt
    18061 gattggtccc aagtactctg aggaaaccat ttaccaagct gctgctgctt ttgaagcaac
    18121 aacagactac cacaaacaac aacccgtgat ttttggaggt gacaactaat gaactttgaa
    18181 acagtcatcg gacttgaagt ccacgtagag ctcaacacca attcaaaaat cttctcacct
    18241 acttctgccc actttggaaa tgaccaaaat gccaacacta acgtgattga ctggtctttc
    18301 ccaggagttc taccagttct caataaaggg gttgttgatg ccggtatcaa ggctgctctt
    18361 gccctcaaca tggacctcca caaaaaaatg cactttgacc gcaagaacta cttctaccct
    18421 gataatccca aagcctacca aatttctcag tttgatgagc caatcggtta taacggctgg
    18481 attgaagtcg agctagaaga cggtacgacc aagaaaattg gtatcgaacg cgcccactta
    18541 gaggaagacg ctggtaaaaa cacccacggt acagacggct actcttacgt tgaccttaac
    18601 cgccaagggg tacctttgat tgagattgta tctgaagccg atatgcgttc gccagaggag
    18661 gcctatgctt atctgacagc cctcaaggaa gttatccagt acgctggcat ttctgacgtt
    18721 aagatggaag aaggttctat gcgtgtggat gccaacatct cccttcgtcc ttatggtcaa
    18781 gagaaattcg gtaccaagac tgaattgaag aacctcaact ccttctcaaa cgttcgtaaa
    18841 ggtcttgaat acgaagtcca acgccaggct gaaattcttc gctcaggtgg tcaaatccgc
    18901 caagaaacac gccgttacga tgaagcgaat aaagcaacca tcctcatgcg tgtcaaggaa
    18961 ggggctgctg actaccgcta cttcccagaa ccagacctac ccctctttga aatttctgac
    19021 gagtggattg aggaaatgcg gactgagttg ccagagtttc caaaagaacg tcgtgcgcgt
    19081 tatgtatctg accttggttt atcagactac gatgctagtc agttgactgc taataaagtc
    19141 acttctgact tctttgaaaa agctgttgcc ctaggtggtg atgccaaaca agtctctaac
    19201 tggctccaag gggaagtcgc tcagttcttg aatgctgaag gtaaaacact ggaacaaatc
    19261 gaattgacac cagaaaactt ggttgaaatg attgccatca tcgaagacgg tactatttca
    19321 tctaagattg ccaagaaagt ctttgtccat ctagctaaaa atggcggtgg cgcgcgtgaa
    19381 tacgtggaaa aagcaggtat ggttcaaatt tcagatccag ctatcttgat cccaatcatc
    19441 caccaagtct ttgccgataa cgaagctgct gttgccgact tcaagtcagg caaacgtaac
    19501 gccgacaaag cctttacagg attccttatg aaggcaacca aaggccaagc caacccacaa
    19561 gttgccctta aactacttgc acaggaattg gcgaagttga aagaaaacta gacagaacaa
    19621 aaccagccct aaggttggtt ttttcttctc taccaactcc caataactat tttggcttta
    19681 tttccagagt attttatggt aaaatgaaga gtaataatat ttattaaaga ggtaaaaaca
    19741 tgattgaagc aagtaaatta aaagctggta tgacctttga aacagctgac ggcaaattga
    19801 ttcgcgtttt ggaagctagt caccacaagc caggtaaagg aaacacgatc atgcgtatga
    19861 aattgcgtga tgtccgtact ggttctacat ttgacacaag ctaccgtcca gaggaaaaat
    19921 ttgaacaagc tattatcgag actgtcccag ctcaatactt gtacaaaatg gatgacacag
    19981 catacttcat gaatacagaa acttacgacc agtacgaaat ccctgtagtc aatgttgaaa
    20041 acgaattgct ttacatcctt gaaaactctg atgtgaaaat ccaattctac ggaactgaag
    20101 tgatcggtgt caccgttcct actactgttg agttgacagt tgctgaaact caaccatcta
    20161 tcaaaggtgc tactgttaca ggttctggta aaccagcaac gatggaaact ggacttgtcg
    20221 taaacgttcc agacttcatc gaagcaggac aaaaactcgt tatcaacact gcagaaggaa
    20281 cttacgtttc tcgtgcctaa tctctagaaa gaggtcattc tatgggaatt gaagaacaac
    20341 ttggcgaaat cgttatcgcc ccacgtgtac ttgaaaaaat cattgctatc gctactgcaa
    20401 aggtagaggg tgttcactct ttttcaaaca gatcagtgtc tgataccctt tcaaaacttt
    20461 cactcggccg tggcgtttat cttaaaaacg tggacgaaga actcacagca gatatctatc
    20521 tctaccttga gtacggagta aaagttccta aggtagcggt tgctatccag aaagctgtca
    20581 aagatgccgt ccgtaatatg gctgatgtag aactcgctgc tatcaatatt cacgttgcag
    20641 gtatcgtccc agataaaaca ccaaaaccag aattgaaaga tctatttgac gaggacttcc
    20701 tcaatgacta gtccactatt agaatctaga cgccaactcc gtaaatgcgc ttttcaagct
    20761 ctcatgagcc ttgagttcgg tacgaatgtc gaaactgctt gtcgtttcgc ctatactcat
    20821 gatcgtgaag atacggatgt acaacttcca gcctttttga tagacctcgt ttctggtgtt
    20881 caagctaaaa aggaagaact agataagcaa atcactcagc atttaaaagt aggttggacc
    20941 attgaacgct taacgctcgt ggagagaaac ctccttcgct tgggagtttt tgaaatcact
    21001 tcatttgaca ctcctcagct ggttgctgtt aatgaagcta tcgagcttgc aaaggacttc
    21061 tccgatcaaa aatctgcccg ttttatcaat ggactgctca gccagtttgt aacagaagaa
    21121 caataaaaag aaaaagtgtt tgatagatat caaacacttt ttctttgcct cccactatct
    21181 aaaaaaatga taatagatat aattgtaaac aaaaatccag ataggttttg catgattgag
    21241 aaagttaaaa aaactatggc agagaatcgt taatctcaga ttgtcggtag aacgataaac
    21301 aagggcaaaa aagaaaccaa tcagactata atataataaa ctaattggat ctctgtgaga
    21361 tagtatcaaa tggctaatcc caaagataag gcctgataag atgacatcta aatagtactt
    21421 tgacttagga aagaaggtat tcataaaata ccctctatca agagtctcct caaaaacagg
    21481 accgatgatt acaagcagga caaaagataa gatagtcgat aaaaaggttg gttgtccatt
    21541 tgaaagaacc acggtaaaat actcatcatg aatattccta tggttaatca aatgagcata
    21601 gcgtgcctaa aaattaccga gaatctgata aaccacataa gttgcaaata aggagaagac
    21661 aaatgaccag tcccagctct ttttcttttt taacctccaa attaatagaa aaggaaactt
    21721 cccactaatc ccactgttaa aataagagaa tagacatcag ctcctaaccc taaaatgatc
    21781 gtcacataca atccaattgt ttgtggtaaa taggtagata gtaaaataat aagcaaaaat
    21841 attccaaatt gtcttagttt ctttgtgttt ctcatcgtac ttttttgaaa gattaccctg
    21901 ttcggaagcc gtacttccaa gcatctatat aagaattaag tgccccttgc ctcatatagg
    21961 gagcaaattc tctataatat aaccatctac tatatccatc ttcccaaaca gcaagaccac
    22021 ctgaagtttg ctccaagtcc tcagttgaaa gaactgtaaa tgtttctgta cctgtcattg
    22081 caagtacctt cttaaaatag attgttgtag gctcacattt atagtatatt tctttttttg
    22141 tctattttat agtctatctc ctcaactggc aatttttcga cctgaattgc atttttccat
    22201 aaaaaatgag acctttctag tctcatttag tcattcttag tattttctaa atcgttgata
    22261 gcgttcttcc agcaactctt ctagcggttt ttgtgaaagt ctagccagct ccgtttggag
    22321 ttcttttttg acactcttaa ttagttcttt actagaaagt cctacttcag aaatcacctt
    22381 atccaccacg tccatttcta acagttcatg cgaagtgatt ttcatcagtt ctgctgcttc
    22441 catggcgcga gtaccgtcct tccataaaat ggaagcaaag ccttctggac tgagaatggc
    22501 atagatagaa ttttccagca tccagacacg gtccgcgaca gctagagcca gagccccgcc
    22561 tgaaccacct tcaccgataa taatggcgat aataggaact ttcaggtcac tcatttccat
    22621 gagattgcga gcgatagctt ccccttgacc acgttcttcc gctccgacac caggataagc
    22681 acctgctgta ttgataaagg tcacaactgg acggccaaat ttctcagcct gtttcatcaa
    22741 ccgcagtgcc tttcggtagc cttctggatg tggttggcca aaattccgtt tgaggttgtc
    22801 ttgcaaactc ttgccttttt ggataccaac cactgttaca gcttggtctc caagccaacc
    22861 aataccacca acaactgcac catcatcacg aaaagaacgg tcaccatgta attggataaa
    22921 ttcatcaaaa atgcctgtcg caaagtccaa ggttgtcaag cgactctgct cacgcgcttc
    22981 tctgactatt tttgcaatat tcatctagga ctccctccat gcaatctgac taggctagca
    23041 atcgtatctg gtaagtctct tcttttgaca atagcatcca caaagccatg ttctaatagg
    23101 aattctgcct tttggaaatc ctcaggcaag ctttcacgaa ccgtattttc aatcacacga
    23161 cgcccagcaa aaccaaccaa gctctgtggt tcagccagaa tgatatcgcc ttccatagcg
    23221 aaagaagctg tcacaccacc agtcgttgga tctgtcaaaa tggtcaggta aaagagacca
    23281 gcatttgaat ggcgtttaac cgctgcagag atcttagcca tctgcatgag actcatgatt
    23341 ccttcctgca tacgggctcc accagaggct gtgaatagga caactggtaa tttttcgaca
    23401 gtcgcatact caaacaaacg agtgattttt tcacctacaa ccgtacccat agaagccatg
    23461 ataaaattag aatccataat cccaagagcc acagtctgac ctttaataag agcagttcct
    23521 gtcacaacgg cttcatgcag acctgttttt tcacgcatag atgccagttt cttttggtaa
    23581 ccagggaaat gcaagggatc cttgctttca atccctgtaa acaattcttt gaaggttccc
    23641 atatcaatcg tcaaagccaa gcgttcttgg gcagaaatac gaaaggtata gctacagtgc
    23701 ggacagatac gttcacttcc cagatccttc tgatagatgg tatgcttaca gcctggacac
    23761 tgggaaaata attcatctgg aacctctggc ttagcttgag gtttttccct aaccgaacga
    23821 ttgggattga ttcgaatata cttatctttt ttactaaata gagccattga ttcccctttt
    23881 cggtttaaac tcttaaagtc attttattct ttttcttgat atttaggtaa gaaggtttcc
    23941 atcaagaagg aagtatcata atccccagca atgacattgc gatctgaaat gagatcaagc
    24001 tggaaatctg cattggtctg cactccttca atctctaatt catagagggc acgttgcatt
    24061 ttcatcaagg cgtcaaaacg attttcgccg tgtactatga ttttggcaat catactatca
    24121 taataaggcg gaatggtata acctggataa actgctgaat ccacgcgcaa gccaactcca
    24181 ccacttggca gatagagatt agtaatctta cctggacttg gagcaaagtt aaaggctggg
    24241 ttttctgcat tgatacgaca ctcgatggca tgaccgcgta ggacaatatc ttcttgctta
    24301 acagacaaag gctgacctgc cgcaatgcaa atctgttcct taacgatatc aacacctgaa
    24361 acaaactctg ttactggatg ttctacctga acacgagtat tcatctccat gaaatagaaa
    24421 ttgctacttg cttcatcaag aagaaattca atggttcctg cattctcata gccaacaaac
    24481 tctgccgctc gaacagcagc agcacctatt tcatgacgca gcgtttttcc gattgcaatc
    24541 gagggacttt cttccaaaac cttttggtta ttcctttgaa gagaacaatc ccgttcaccc
    24601 aagtgaatca catgtccatg ctcatcacct aggatttgaa cctcaatgtg ccgagctgga
    24661 tagataaccc gttctatgta catggcacca ttgccataat tggccttggc ctcactagag
    24721 gcagtttcaa aggcagaaac gaggtcatct ggtttttcaa ccttacgaat ccctttacca
    24781 cctccacctg ctgaagcctt gagcataaca ggatagccaa ttttttcagc aacaatcaaa
    24841 gcttcttcag agttatgcac ttctccatct gaacctggta taacaggcac acctgcttta
    24901 atcatctgag cacgcgcatt gatcttatcc cccatcatat ccataacatg accagatgga
    24961 ccgataaact tgatacctac ttcttcacac atggtcgcaa atttggaatt ttcactgaga
    25021 aatccaaaac cagggtgaat agcttctgcc tcagtcaaga ctgcagctga tagaactgca
    25081 ttaatattga gataagactc tgttgccttg ccaggaccaa tacaaactgc ttcatctgcc
    25141 aacagcgtat gaagagcttc cttatcagca gttgaataaa ccgctaccgt cgcaatcccc
    25201 aattcacgtg ccgcacggat aatacgaacc gcaatttcac cacgattggc aattaaaatt
    25261 tttcgaaaca tggagaacct ccttagttcc caattgcaaa agtaagggta ccactggctg
    25321 caagcttgcc atccacttca gcctttgctt caaccacagc tatggtgcca cgacgtttta
    25381 caaaagtcgc tgtcataacc aattggtcgc ctggtacaac ttgcttcttg aacttaacct
    25441 tatccatacc agcgtaaaag accagttttc ctttattttc aggttttgat aactccaaca
    25501 caccagcagt ttgcgccaag gcttccataa tcagaacacc tggcataact gggtattgag
    25561 gaaagtggcc gttaaagaaa ggctcgttga tggtcacatt tttgatagca acaatggtat
    25621 cctcgctcac ctccaagaca cggtccacta gaagcatagg ataacggtgg ggaagggctt
    25681 ctttgattcc ttgaatatcg atcatttgat acgtaccaat cctttaccaa actcaaccat
    25741 ttcttcgtta gagacgagaa tttccgttac cacaccatcc ttaggagctg ggatttcatt
    25801 catgactttc atggcttcga taattaccaa tgtttgacct tttttgacac tatcaccaac
    25861 tgtaacgaag gcaggtttat ctggtccagc agccaagtaa accactccaa caagtggact
    25921 ctctacaaga tttccctcac tagccacact tgcttcagct ggagctggaa cttcttctgc
    25981 tacagtctct gctggagcag atgtaggagc tactggactc ggtgttgcta gaacgggtgc
    26041 tggagcgact tgagttgcaa cttcaggcac aggtctcgct tcattcttgc taaactgcaa
    26101 ctcatccgtc ccatttttat aagaaaattc tctcaaactt gactggtcaa attgagtcat
    26161 caagtcttta atatcgttta aattcatact tatctattct cccaacgttt gaaagcaaga
    26221 actgcattgt ggcctccaaa accaaaagta tttgaaatag cgtatggaat ttctttctcc
    26281 aagccttgtc cataaacgac attagcttcg atataatctg atacttcact tgtcccagct
    26341 gtcattggta caaagttatg acgcatagct tcgatggtga cgatagcttc tactgcaccc
    26401 gcagccccca gcaaatgtcc tgtaaaagac ttggttgatg atacaggtac ttccttacca
    26461 agaacagcta cgatagcacc actttctcct ttttcattgg caggagttga cgttccgtga
    26521 gcattgacat aggctacttg ctctggagaa atctcagctt cttccaaggc tagtttgatg
    26581 gccttgatag ctccctgacc ttctggatgt ggagaagtca tgtggtaggc atcacaagta
    26641 tttccgtaac caaccacttc agccaggata gtagctccac gtttttcagc gtgttcaaga
    26701 ctttctagaa ccaacatccc tgaaccttca cccataacaa acccattgcg atccttatca
    26761 aatgggatcg aagcacgagt tggatcctct gtagtagaga gagctgttaa ggcttggaaa
    26821 ccagcgatgg caaaaggtgt gatagaagct tctgttcctc ccaccaacat cacatcttgg
    26881 aaaccaaact taatggagcg gaaggcatcc ccaatcgcat catttgatga agagcaggca
    26941 gtattgatag atttacaaac accgtttgca ccaaaacgca tggctacatt cccagaagcc
    27001 atatttggta aagcttttgg aagagtcatt ggtttgacac gtttgggtcc tttttcatga
    27061 aggcgaagta cctgatcttc aatttccttg attccaccaa taccagatgc aacgataaca
    27121 ccaaaacgat ccctattaag agcctctaca tcaagattgg catgatttac agcctcttgg
    27181 gctgcataca aggcatataa agaatagtta tcaaaacggt tggtatcttt ttttacaaag
    27241 tatttatcga acggaaaatc ttggatttct gccgcattat gcacatcaaa gtcactatga
    27301 tcaaattttg taatgccacc aatgccgatt ttcccagttg ctaaactatt ccaaaattct
    27361 tctggtgtat ttccgattgg agatgttact ccataacctg ttaccactac tcgatttagt
    27421 ttcattcttt tcacctctag ctttcgctac atacttaagc caccatcaat ggcaatcact
    27481 tgaccagtta gataatcttg gcctgctaaa aatactgtca aatctgcaac ctgctctgcc
    27541 tgcccaaatt ctttcatcgg aatctgagct agtgtagctt ccttaatctt atctgataag
    27601 atagctgtca tatcagactc aatcattcct ggagcaatca cattgactcg tatattccga
    27661 ctagcgacct cgcgtgccac agacttggta aagccaatca agccagcctt agaagcagca
    27721 tagttagctt gaccaatatt ccccatcaaa ccaacaacac tagacatatt aatgatagca
    27781 ccttctctgg ctttcatcat cggtttcaag actgattgtg tcatattaaa ggcaccagtc
    27841 agattgacct tgagcacttt ttcaaaatct gcttctgtca tcttgagcat aagagtatct
    27901 tgggtaatcc ctgcattgtt gaccaaaaca tctactgaac ccagttctgc aatagcttga
    27961 tcaatcatac gcttagcgtc tgcaaaatct gatacatctc ctgaaatggg aaccaccttg
    28021 ataccatagt ttgaaaactc agcgagcaat tcttctgaga ttgccccacg actgtttaag
    28081 acaatgttgg ctcctgcttg agcaaacttg tgggcgatgg caagaccaat tccacgactc
    28141 gaacctgtaa taaagatatt tttatgttct agtttcattt ttttcctttc aaaacttcta
    28201 cttattttag tctatttttc taaaagtgct actaaactcg cttgatcttc cacatgagct
    28261 aagtgagcag tttgatcaat ttttttaaca aaacctgaca agactttccc cggtccaatc
    28321 tcgataaagt tgcttatgcc tgcttcttgc atgaccccaa tactttcata gaaacgaacg
    28381 ggttccttga cctgacgcgt caagagctga gcaatgtcct ctttttgcat cacagcagct
    28441 tctgtattgc cgactagggg acaagtaaaa tctgaaaaac ttacctgagc tagagtttca
    28501 gctagtttct ggctagcagg ctcaaggaga gcggtgtgaa agggacctga caccttaaga
    28561 ggaatcaagc gtttggcacc tgcttcttgc aaaagttcaa ccgctcgatc aactgcaacc
    28621 acttctccag caatgacgat ttgtgcaggt gtgttatagt tggctggagt aaccactcca
    28681 agttcagaag ctttttgaca ggcttcttca atgacctcta ctggcgtatt gagaactgct
    28741 accatcttgc cagagtcagc aggagccgct tcttccatat aggctccacg cttagctacc
    28801 aaggcaaccg catcttcaaa atccaaggcg ccgcttgcca ccaaggcaga gtattctcca
    28861 agagacaaac cagcaaccat atcaggctga tagccctttt cttgcaataa acggtagata
    28921 gcaaccgaag tcgctagaat ggctggttgc gtatagcggg tctgattgag tttgtcttct
    28981 tccgtatcga tgagataacg taaatcataa ccgagcacct gactcgctcg atcaatcgtt
    29041 tctttaacaa tcggatactg atcatagaaa tcccgtccca tccctagata ctgggcacct
    29101 tgaccagcaa ataaaaaggc tgttttagtc atttcttaca actcctgccc agcgagaggc
    29161 ttcttcttga attttcttag cggctccgta atacaaatct tttaggattt cttcagctgt
    29221 ttcttcttta gaaacaagcc ctgcgatttg acctgccatg acagagccac cctccacatc
    29281 accgtgaaca actgctttgg ctagggcacc tgctcccatt tgttcaaaga tttctaaatc
    29341 aggatcttcc tgcttaaagg catctttttc agccagttca aaatctctag tcaactgatt
    29401 tttaatagca cgaacagcat gaccaaagtg ctgagctgaa atcgtagtat caatatccct
    29461 tgcttttaaa attttctctt tgtagtttgg atgggcattc gactcttttg caactacaaa
    29521 ccgtgtcccc acctgtacag cctctgcacc tagcataaag ccagccgcag caccttcacc
    29581 atccgcaatt cctcctgcag caataacagg aatagatata gctgtggcta cctgtcgcac
    29641 caaggtcatg gttgttaatt taccgatatg ccccccagct tccattcctt ctgcaataac
    29701 agcgtctgca ccgatttttt ccatgcgttt agctaaagcg acactaggaa caacaggaat
    29761 aacgattatc ccagcttcat ggaaacgttc catatacttg cttggatttc ctgctcctgt
    29821 tgtgacaact ttaacacctt cttcaataac gagatccacg atatcttcca caaagggaga
    29881 taagagcatg atgttgaccc caaagggttt atcagtcaat gatttgattt tatcaatatt
    29941 ggccttgaca acttctttcg gggcatttcc cccaccgata attcctaatc ctccagcctt
    30001 ggaaacagcc cctgccaaat caccatcagc aacccaggcc atccctcctt ggaaaatagg
    30061 atagtcaatc ttcaataatt ctgtaatacg cgttttcata gtgcctccaa ccttccttgc
    30121 ttacgtaata gttcgatttc accataattt gacagtcaaa ctattaccta aacaagaggg
    30181 agtgggtttc tccctactcc ttctactaat attctgctta ttttgcttgc tcttcaacgt
    30241 aagcaaccaa gtcaccaact gttttcaagt cattttctgc ttcgatttgg atatcaaaag
    30301 catcttcgat ttctgagatt acttggaaca agtccaatga atctgcgtcc aaatcatcaa
    30361 aagttgattc aagtgttact tctgatgcgt cttttccaag ttcttcaacg ataatttctt
    30421 gtactttttc aaatactgcc atgataggac tcctttaaaa taaatagttt ttttataaca
    30481 atgtgttcac cacatgatta cctaaattgt aagaatgagc gtgccccagg tcaagcctcc
    30541 accgaagcct gatagaagaa cagtttggct accatctaaa gggatgagac cttgttctac
    30601 acactctgaa agtaaaatcg ggatactggc tgcactggta ttgccatatt ccatcatatt
    30661 agctggaagt ttggctcggt caacaccaat ttttctagcc atcttatcca aaatacggtt
    30721 attggcttga tgaagtagca gataatccaa gtctgtcacc tctataggag attcatcaat
    30781 agtctgcttg atagacttgg ctacatctcg aatggcaaaa tcaaagactg tgcgtccatc
    30841 catcttcaaa aatgaatctg cactttcttg atctgaaaat ggagaatgca aacctgaatg
    30901 cccataagtt aaacactcgc tgcgacttcc atcgctattg agactctcag ctaagaaatg
    30961 ctcttgctcg ctagcttcta acaagacacc accagcacca tctccaaaca acacagctgt
    31021 tgatcgatcc gaccaatcga ctgccttaga gagggtttca ctaccaatca ccaagccttt
    31081 ttgaaagcga ccagaagcga taaacttttc agcagttgaa agagcaaata caaatccact
    31141 gcaagccgcg gttaagtcaa aagcaaaggc tttattagca ccaatattag cttgaacacg
    31201 agcagctgta gagggcatca tcgaatctgg agtaatggta gctaggatga taaaatccag
    31261 ttcttctcct gttattccag cttttgccat cagtttctta gcaacctctg tagccaaatc
    31321 actggtagat tctgttcttg aaatatgcct ttgtcgtatt cccgttcgac ttgaaatcca
    31381 ctcatcattg gtatccataa tctgagccaa gtcgtgattt gtaaccactt gctctggcac
    31441 ataatgagca acctgactta tttttgcaaa agccattatt tcaaatcctc caaaaattgg
    31501 taaagattag tcaaaccttt acccatgaca gcaatttctt cctcgctcat gccatcaata
    31561 attttttcta ccatggcctt gtggaagcgt ttatgcagtc tatgaatcaa gcgacccttc
    31621 tttgtcaaat gcagatgcac cacacgacga tcctgttctg accgaactcg ctcaatgtag
    31681 cccttacgct ctaaattgtt caaacttgtc gtaacagttc caagagttac catcaactct
    31741 tttgacactt gacttggagt cacatctgga gccttaccga tgacatcaat cgtatgcatt
    31801 tctttgatgg agatatcctt aaaacgacta cctctcaagt tcacttcctc aattacaagg
    31861 acattgttaa atatagatgt taaatattca ttgattcgtt ggtagtccat ttttcatatc
    31921 cctccttctt caaaaaactt ttacaatcaa aacatttgac agaaagaatt atatcaaaat
    31981 tcaaagaatg atgcaagtat tttttatttt cctgtaaatt taggtcttct tctctccgaa
    32041 tgagctcgca ctccttcttt gaaatcctct gtttgagcta aggatttctg taggttcagt
    32101 tctaaagtag cgtaaccctg ccagtcttta aattggctct cccaaaccaa cttcttaatg
    32161 gcagcatagg aattacttga agcacgtctt aattttttaa gaagctgttc tctcgtcttt
    32221 tcaagttttt cagcttcaga aacgcggtaa accaaccccc attctagggc tttttctgcc
    32281 gttaaagcct ctcctgtcat agctaattga gcagcacgcg tcacaccgat actgcggctc
    32341 aagagatgaa ttccccctgc atctggagcc aaaccaacac caacaaaggc ttggataaac
    32401 ttagccttat ccgtcgccaa acagaaatct gccgcaacag ccatattcgc tgcggcacct
    32461 gcaacagcac cgtcaacttc cattaaaaca ggtttggcta tttgcttgat tttataagaa
    32521 atcgtattga ccaactctgc gatttttgtc aatgatggaa tatcatcctc atccactgcc
    32581 cgcttcatct ctaccaaatc tcccccaact gagaagacct ttccattggc attgattaag
    32641 ataaaatgca cagctggatt ttcttctgcc aaagtcagag cttctaaaat ctcctcacac
    32701 atgggaatat gaaaaccatt tgcgacctca ggacggttca aggtaaggat tgccaagtcc
    32761 tcttcaagct gataaataat gtgttccatc agggctcctt tttattttat aagcagttta
    32821 tactcttcga aaatctcttt aaaccgcgtc agcttccatc tgcaacctca aaacagtatt
    32881 ttgagctgac ttcgtctagc ttcttagttt gctctttgat tttcattgag tgttaaatta
    32941 tttcactgtc aaagtatatc ttttttagga gcagaaagca agaaaaaatc gactgaaagt
    33001 gtctcagccg ataagaaagg ctcgctttag gctagaaagc atcttatttt cttcattgaa
    33061 aaaagccttt ctttctgcta taatcgtata aaatacttac tttaggagtt cttatgaaag
    33121 ttgttaaatt tggaggtagt tctcttgcct ctgctagtca attagaaaaa gttttaaaca
    33181 tcgtcaaaag cgattcagag cgtcgttttg tagtcgtttc tgcgcctggt aaacgcaatg
    33241 ctgaagatac taaggttacg gatgccctga ttaaatacta ccgcgactat gttgcgggta
    33301 acgatattag caagagccaa agctggatta tcgaccgcta tgctgctatg gttagtgaat
    33361 tgggactaaa accagctgtg ctagaaaaaa tttctaaaag cattcacgcc ttggccactc
    33421 ttcctattga agaaaatgaa tttctctacg atactttcct agcagccggt gaaaataaca
    33481 atgccaaatt gattgctgcc tactttaacc aaaatggtat cgatgcacgc tatatgcacc
    33541 ctagagaagc tgggattgtg gtcacaagtg aacctggtca cgctcgcatc attccatcaa
    33601 gttatgacaa gattgaagaa ttgacaaaca ccaatgaagt ccttgtcatt cctggtttct
    33661 ttggtgtcac taaggaaaat caaatctgta ctttctcacg tggaggttct gatattacag
    33721 gttctatcat tgctgctggt gtcaaagctg acctctatga aaactttacg gacgttgatg
    33781 gtatctttgc agcccaccct ggtattatcc accaaccaca ctcgattcct gagttgacct
    33841 accgtgaaat gcgcgagttg gcctatgcag gcttctcagt ccttcatgac gaggctcttc
    33901 ttcctgccta ccgtggaaaa attcctctgg ttatcaagaa taccaacaac cctgaccatc
    33961 caggtactcg tatcgttcta aaacacagta atgatgaatt tccagttgtg ggaattgctg
    34021 gtgactcagg ctttgtcagc attaacatgt cgaaatacct catgaaccgt gaggttggat
    34081 ttggccgcaa ggttctgcaa atcctggaag aacttaacat cggttgggaa catatgccaa
    34141 caggtatcga cgatctttct atcattctcc gttctcgcca actaactccc atcaaggaag
    34201 aagaaatcct gcgtcagttg gttcaaaagg ctaaagtaga tcatgcagaa atcgaacacg
    34261 acctttctat cattatgatt gttggtgaaa aaatgaagag ccatatcgga gtgactgcta
    34321 ctgcgacacg cgctctatct gaaaacaaaa tcaacatcca gatgatgtct caaggttcta
    34381 gtgaagtttc tattatgttt gttgtcaata aagaccaaga gaaagcagca attaaagccc
    34441 tctacaatgc cttttttgga gaaagtaagg aagactaagc atggcccaat cacttaacaa
    34501 aacagtactc ctcagtacga caggcacttc ctacctctct atcgctggga aagttgggaa
    34561 attccttgtc ggagatcagg ctttggaatt ttacccagat gtcaatgtcg aacaatttat
    34621 ccagattcct tggagccata tcaatcagat tggagccaat gtcactggac gcaaaatcag
    34681 ccgccacttc gaagtcttta cagacaaagg aaaattcctc tttgcttcaa aagactcagg
    34741 tgccattctc aaaattgcac gcgaaaaact aggcaatgac aaggtcgtca aacttccgac
    34801 cctgattcag acaattagcc aaaaatttaa aaatctattt gcaaaaaagt agaaacttta
    34861 gtataatcat agcaacggat aagtaggtta tcttcttctt tcagaaagtc tgcgggtact
    34921 gcgagcagat aggggggata ggtgaaattc taccgttagt aacaattaca tacacaatca
    34981 agtgcacacc tgtgaagttg gatggaaccg tggccctgcc actccaacgt tttgtcaggc
    35041 gtgctttttt cataaaggag ttcttatgtt agatatcaaa cgtattcgta cagattttga
    35101 agctgtcgca gaaaaattag ctacacgtgg tgtagatgct gctgtcttga atgaaatgaa
    35161 agaaatcgat gctaaacgtc gtaacatctt ggtcaaggtt gaaactctca aagcagaacg
    35221 taacacagtt tctgctgaga ttgcccaagc taagcgcaac aaggaaaata cagatgacaa
    35281 gattgctgcc atgcaaaatc tatctgctga ggttaaagcc ttggatgctg aattggcaga
    35341 aatcgatgct aaattgacag aatttacaac gactcttcca aatatcccag ctgacagcgt
    35401 tcctgttggg actgacgaag acgacaatgt ggaagttcgc cgttggggta ctccacgcga
    35461 gtttgacttc gaacctaaag ctcactggga tctcggtgaa gaccttggta tccttgactg
    35521 ggaacgcggt ggtaaggtaa caggcgctcg cttcctcttc tataaaggcc tcggtgctcg
    35581 tttggaacgt gctatctaca actttatgtt ggatgaacat ggaaaagaag gctatactga
    35641 agtcatcaca ccttacatag tcaaccatga ttctatgttt ggtactggtc agtatccaaa
    35701 atttaaggaa gatacttttg aactcagcga taccaacttt gtcttgattc caactgctga
    35761 agttcctctg acaaactact accgtgatga aatcttagac ggcaaagatc ttccaatcta
    35821 cttcactgcc atgagtccgt cattccgttc tgaggctggt tctgccggtc gtgatacgcg
    35881 tggcttgatc cgtttgcacc aattccacaa ggttgaaatg gtcaaatttg ccaaaccaga
    35941 agaatcttac gaagaattgg aaaaaatgac agccaacgct gaaaacattc ttcaaaaact
    36001 caaccttcca taccgtgtcg ttgctctctc tactggagat atgggcttct cagctgcgaa
    36061 gacttacgac ttggaagtgt ggattccagc acaaaacaat taccgtgaaa tctcaagctg
    36121 ttcaaacaca gaagatttcc aagcccgtcg tgcccaaatc cgttaccgtg atgaagcaga
    36181 tggcaaggtg aaactccttc ataccttgaa cggctctgga cttgcagttg gacgtacagt
    36241 ggctgcaatt cttgaaaatt accaaaatga agatggttct gtgaccatcc cagaagcact
    36301 tcgtccatac atgggtggag ctgaagtcat caaaccataa aaaataaggt ttagctattt
    36361 ctagctagac cttttttcgt aaccaaatca gataagcacc tagtacaaag aataaaatag
    36421 ttaggcatat aatggtttca gccaatacca ggtaatccag aaatggaagt ttcaaaattc
    36481 cctgagccat cttgagcgag gtcgctgtga taatggttgg gaaggtgagg gctgagaagg
    36541 ctggttgaaa accttgtttt aaaatgttgg gcagacgagt taaaacaaag aaaaagaagg
    36601 attgagaagc caaaatcatg acaatcaaga cccaagtcgg caggctggtt cctcctactc
    36661 gaactagaga agccaagagt agagagaaag gagcacagta gattccttct tgtccaagca
    36721 aggctagtgg gagtggatgt ttctttaaat cgctataaat aaggggatag agatagaagg
    36781 tcaagagaaa accaaaactc aaggtcgcat aggcaatttc gataatacct accagaggat
    36841 aggtcaaggc agccactgct atccccacat agagaaccgt ccaacttgga gtggcatgaa
    36901 ccctccgccc tgaacaagca aacttgatgg taaaaccagc aatcaaggtc aaatccaaga
    36961 gaaatgaaaa ccaccaaatc ccttgtgcta ccaaaggaag ataagagaat acgcgaaaga
    37021 cataggtcga taaaatcatc ccagccatag gaaaggttgc cattcctgac aaaagagggg
    37081 gcttggtcaa ttcttgcttg gtttctttcc aattaaagag atgcagaatt agaaagtaaa
    37141 tccataaaac caaaccagtc agactaaaaa gatgggatag aaccggcaac gtatctaaaa
    37201 taagatttcc agctcctgcc aaacctagca aacaacctga aaatactaag gggagttttt
    37261 tcatcctaac ctccaataat catgttagtt tcagtataac ataaaagcgc ttaaatgagg
    37321 atttaaaaaa acgaagtccg cttatttcag acttcatttt actcagatat gaattaggca
    37381 taaggttgca attctggatt aattggtgta ttagctaagt tgttggcata gttacagagg
    37441 attgctaggc tgacaccaaa aaccacatcc aaggcatttt gttgagtgta gccagcttct
    37501 aaaaactcag acaaggcttc atctcctaca cgacccttgg tattgataac tgccaaggta
    37561 aacttagcta gggtatccaa tttaggatct gtttcaattg gagtacgatt gcgaagagct
    37621 tgaatcaagt catcattcat ctggatttgt ttgatggaaa aggctgtgtg acctgcgaca
    37681 cagaaggcac aaccattggt cacggctgcc gtgatttgca ccacttcacg ctcaacgggt
    37741 gtcaggctgt tgcgacggtg gatagatgag acaatttggt aggcttctaa aacagtcggg
    37801 gcattggcca agagaccgat taggttggga atatagccat tgttgtcttt ttctactgtt
    37861 tcaagaattt ctttcacttc tgctggtgct gactctactg tatggatagt aaatgttgtc
    37921 ataagatacc tcttttctta ttattgacac taatattatt ggaaaatctt ataaaatcct
    37981 gattcctaag tttatctaag ataaagcttt attctctcat aagattttcg ttgttatatt
    38041 agtttatcac acttccaatc acttgcataa tatatattat atatcaggct gataaaaatt
    38101 atttataggc aaaaaaatca cacgagctgt gtgattccat tatttgtcaa aatacttttt
    38161 agtttcagca ataacgactg gcgacaagac caagagggca atcaagtttg gcagagccat
    38221 caaggcgtta acgatatctg cgataatcca gaccatatcc aactcgataa atcctcctaa
    38281 caagaccatg agcacaaaaa acacacggta gagccagata aagcgagccc caaagaggaa
    38341 ctcaaaacag cgttctccgt aatagttcca acctagaatc gttgtaaagg caaaaagtac
    38401 aaggaagatg gtcaagaggg caggcccaaa gtgtgaaaag actgttgaga aagctgactg
    38461 agtcaaggca accccattca agtcaccact ccaaactcca gttaccaaga tggtcaaacc
    38521 agttagagta caaatgatga gggtatcaat aaaggttcct gtcatggaaa tcaaaccttg
    38581 ctctactggt tcatttgtct tggcagctgc agctgcaata ggagcagaac ccagaccaga
    38641 ttcgtttgag aacacaccac gcgccacacc attttgaata gccatccgaa cgctagcacc
    38701 agcaaatcca cctaccgcag caaggggact aaaagctgag gtaaagacta aagcgattgt
    38761 gccagggatt tttccgatat taaagaaaat aactgtaaga gttcctaaga tataaatgag
    38821 ggccataaaa ggaacaacag tagttgaaac cttagaaata gacttgagtc caccaaagac
    38881 tgcaatcgct acaaagacag acaagacgag agctgtgatg gctggcgaaa tcgtcgttgt
    38941 attttggata gattctgtaa tcgagttgac ttgggtgaag gttccgattc ccaagagagc
    39001 aaccaatact cctgctactg caaacaaaac agcaagtggt cgccactttt ctcccatccc
    39061 tagaaggata tagtgcatgg gacctcccgc tactgcacca tggtcgtcct tggtgcggta
    39121 tttgatggcc aagagtcctt ccgcatactt ggtagccatt ccaaagaaag ccgccatcca
    39181 catccaaaat agagctcctg gtccaccaac cttgatagcc gtcgcaactc ctatgatatt
    39241 tcctgttcca acagttgatg ccaaggctgt acacagagct gcaaaactgg atacatcacc
    39301 atgtccctta tcctggataa aaataagctg aaaggccttg ggcagacgca aaacctgcaa
    39361 gagtcctagc cgcatggtta ggtaaatccc tgttccgacc aataaaatca agaggggcgg
    39421 tccccaagca aaagcatcga ttgatttaag caattctaac atttccttct cctatcgttt
    39481 caaccccaaa agaaagagca catgcaagat acatgtactc tggaatgctt agataaatgc
    39541 taaaaagcgg tctatcctag ctctgtcctt ttacctgaga gtttgagcag ttgcctgcct
    39601 tgccccttcg gtgcctttac ggtctctcca gagttccgtc catttacagt catggaaaat
    39661 caaacgattc cccacttcta ttaaacttca ttcggtgttg gtatttaatt gattctaatt
    39721 ttacaaaaaa tgttggcttt tgtcaatgtg tttattagta aaaattagtt caacagtttt
    39781 tactttataa agtccagaat actgctatcc tttaaaagtg acaatagtcg caccactgcc
    39841 tccagcattt tgtggggcat agccgaaact cttgacatgt ttgtttcttt gcaagtattt
    39901 ggtaactcct tcacggatga ctcctgttcc gataccatgg atgatatcaa cttgagccat
    39961 attgttaagc aaggcttggt cgatgaaggt atctagctca ttcatggctt cttcatagcg
    40021 cttgcctcga agatccagtc tagcttgagg tcctcgccca gaagttcgtt tcacaacatt
    40081 gacctgtttc ttcttgactg gtttttcttg ctgggcttga acaagatcaa actctttctc
    40141 ttccaaggtc atcttaatca agccaacttg ggcttcccag cgaccgtcct tgagttgact
    40201 ggtcaaggta ccacgctgac cataactgag aaccacgata tcatctccca cctttggagc
    40261 tcgttttttc ttggcctttt gaaggacctt atttttagac aagtccactt tttcaggagc
    40321 caattttttc aacttggcct tggcttcaat gatttcgtgg ggcttgagtt gggatttact
    40381 gtggagattt ttgagaatct ggtcactttc acttagggcc atatccacaa tctcagcagc
    40441 ctgttcacgc gccttgttaa gctcggtttc cttttcacga ttaagctcgt tgtagagttt
    40501 ttttagcgca cggttcatct tgagattttc ttgctccacc tcacggatat tgtccaaacg
    40561 tttgcggctt tccagcgtct gctcttctaa ttgctcaatg atacgattga cgtcattgtc
    40621 ctgatcgatc tgctgactgg catctcctac gataacttca gataggccta gacgtttggc
    40681 aatttcaaag gcattacttc ggccaggaac accctgcata aagcgatagg tcgggcgaag
    40741 agttgcagta tcaaactcca tactggcatt ttgcacaaag gctgtctcaa taccgtaggc
    40801 cttgagttct ggatagtggg tcgtcgccat ggtcttgatt tgacgcaggc gaaggtcctc
    40861 cagaatagcc atggcaaggg ctgctccctc ttggggatca gtaccagccc ccaactcatc
    40921 caaaagtaag agtgaatgtt ggttgacctt gccaagaata tccacgatat tggtcatatg
    40981 gctagagaag gtagacaagc tctgctcaat agactgctca tctccaatat cagcaaagat
    41041 ttcttcaaaa ataccaacac gacttccctt gtctgctaaa atcggcaatc ctgactgggc
    41101 catgacctgt gtcaagccca gagttttgag catgatggtc ttcccacctg tattgggacc
    41161 tgtaatgaca atagctgtta aatcttgacc aaaatggaca tcatttgcga cggcattttt
    41221 gaccaaagga tggcagacat ggagcagttg aatctcttga ttttctgaca gctgaggcac
    41281 gactgcttgt ctttcttgga taaatcgaac cttggcacga atcaagtcca gatgaccgat
    41341 aatccaagcg tcattagcaa tctcagccgc atgagggcgg acacgctcag aaatttcttg
    41401 gagaatgcga agcatttcat agcgctcatc tgctcgcaga ctagcaattt cttcgctcag
    41461 tttgactacc tcacgtggtt cgatatagac ggtgtttcca ctagcagaaa tatcatgaac
    41521 gacacctgca atcttattgc ggtaggtgtt tttgactggt aaaacctgac ggccatttct
    41581 gctagcaaca attccttccg tcaacatctg cgctttttgc ttgagcaagt cttgtaaaac
    41641 atcgcgtacc tgactctcgc tatcatgtat ttttcgacgg attcgcgcca attcttcact
    41701 ggcaaaattt tcaatgaaac ccgcatcatt aaaggcctga agatttcctt gtaattgcgg
    41761 aaaatcatgt aatttctcaa accaaagggc taattcttcc aagctgacat tttccagatt
    41821 ggcataaaaa ctttgaagtt ctcggctggc aagaagcacg cgtttcaaga gtaggaactc
    41881 ctcgatattg agatccgctc ccatctccaa cctcttgcag actcctgcaa tttccttagt
    41941 tgagagaata gtaaaatgcg gttgctcgac gaaaagagcc tgcatttctt tcatctcagc
    42001 aaaagcctgt ttgattttat ctgctttggc agtcggagcc agctgtctca attgctccaa
    42061 gccctgctcg gtcaacaaat gaggatcaaa caaggccttg accttatcga actctaatgt
    42121 ttctaatatt ttcttattca tctttatttc cttgtctttg aatgtctagg tgtggtagct
    42181 ttttacattc tgatagattc gagtcaaatc tgtaaacaaa gggctaggaa aactcctgcc
    42241 ctttttatcc gattaaattt gtcacccaga tttgtttgag ccaactggtt gttatcggta
    42301 tgctctggat gatgtgtttt gcgacgatac tcttttcaag aggattttgt ataactgcca
    42361 tggggatggt cgccaagatt gtcaaggcca tttgcaagac aaataaggtc accaacatgg
    42421 acaagatacc tgctgaaact tggaacaact taccacccag ttttttgcta ggaatcaagt
    42481 gtaagagaag accaagcaaa cgaccaatgc tatagaaaat cccaaataca agcaagtagc
    42541 cgatacctgc ataaaagacc ttatccagct gaaagagttg atccgatggg aaaaagaaag
    42601 tcccctgacc ttcctgcgaa tttgcataag ggagcaataa atggaattgc tctccaagcc
    42661 ccttataaaa ctggccagcc ataaaagccg atgccatggc tgaaatcagg taataaacct
    42721 gtaagagcag gcctctccga tagccgatat aaaatcccca aaccaagacc aatagaagaa
    42781 ggaatgaaat cataaggaat cctcaatctt gctctgttct tgcttacaag tcacaagctt
    42841 gtgacggagt tcttctagct cttgctcctt atcgtcaaat tcaatctcac ggctgagctg
    42901 agttgataaa cagttgactg ccaacaaaag agcgattgtt tcatcatctg cgctaggcat
    42961 ttgttcttta attgcttggt atttttctgt cgcaacctta gcgatttcct ccataaaaag
    43021 gttatcatgt tcgcttgtca aggttaacga ttttttcccg aatgtaaatt tgaatcgatt
    43081 tagatttgcc ataaaattca cctcacgata ttataccaaa attcgctaat tttgtcagtt
    43141 tttacaaatt ttactgcttt tgtggtacaa tagaaactat ggcaagtatc acactcacac
    43201 caagcgaaaa ggatattcag gcttttcttg aacactatca aaccagtctg gctcccagta
    43261 agaatcccta tatccgctac tttttgaaac tacctcaagc aacggtttct atctatactt
    43321 ctggaaaaat cttgcttcag ggtgaagggg ctgagaaata cgctagtttc tttggctatc
    43381 aacttgtaga ggaaaacagg gggcaaaatc ttcctttaat tgggacagat gaggtgggaa
    43441 atggttccta ctttggtggg cttgcagttg tggctgcctt tgtcacatct gaccagcacg
    43501 actttttacg aaaactcggt gtgggggatt ctaagactct gaccgaccaa aagatccgtc
    43561 agattgctcc tattctcaag gaaaaaatcc agcaccaggc actccttctc tcacccagca
    43621 agtacaacga ggtcatcgga gaccgctaca atgctgtttc ggttaaggtt gccctccata
    43681 atcaggctat ctatctcctc cttcaaaaag gtgttcagcc tgagaaaatt gtgattgatg
    43741 cctttaccag tgctaaaaat tatgacaagt acttggcaca agaggccaat cgtttcagca
    43801 atcctatcag cttagaagaa aaggctgagg gcaaatactt gtctgtcgca gtttcttctg
    43861 tcattgcgcg tgatctcttt ctggaaaatc ttgaaaattt gggacgagaa ctgggttatc
    43921 agctcccaag tggagctgga acggcttctg acaaggtggc tagccagatt ttgcaagcct
    43981 atggtatgca gggactcagc ttctgcgcca aattgcactt taaaaacact gaaaaagcga
    44041 aaaaacgctt agaaaggtaa gttatgaatt catttaaaaa tttcttaaaa gagtggggat
    44101 tgttcctcct aattctgtca ttactagctt taagtcgtat ctttttttgg agcaatgttc
    44161 gcgtagaagg acattccatg gatccgaccc tagcggatgg cgaaattctc ttcgttgtaa
    44221 aacaccttcc tattgaccgt tttgatatcg tggtggccca tgaggaagat ggcaataagg
    44281 acatcgtcaa gcgcgtgatt ggaatgcctg gcgacaccat tcgttacgaa aatgataaac
    44341 tctacatcaa tgacaaagaa acggacgagc cttatctagc agactatatc aaacgcttca
    44401 aggatgacaa actccaaagc acctactcag gcaagggctt tgaaggaaat aaaggaactt
    44461 tctttagaag tatcgctcaa aaagcccaag ccttcacagt tgatgtcaac tacaacacca
    44521 actttagctt tactgttcca gaaggagaat accttctcct cggagatgac cgcttggttt
    44581 cgagcgacag ccgccacgta ggtaccttca aagcaaaaga tatcacaggg gaagctaaat
    44641 tccgcttctg gccaatcacc cgtatcggaa cattttaaga gacctaagag gccgagaatc
    44701 accaatctca gcctcttctt ctatcgtgag aagtgattgt ttattgacaa atactcaacg
    44761 aaaatcaaag aacaaactag gaagctagcc gtaggctgct taaaacagtg ttttgaggtt
    44821 gtggatagaa ctgacgaagt cagctcaaaa tactgttttg aggttgcaga tggaagctga
    44881 cgtggtttga agatattttc gaagagtata aaataaaaac aatcccaact ctcacctatt
    44941 catgcaaagg aattttatgg aagtttattt ttcaggaacc attgaacgga ttatttttga
    45001 aaatcccagc aatttttatc gcatcctcct cctagaaatc gacgatacgg acgcagagga
    45061 ttttgatgat tttgaaatca ttgtcacagg aaccatggct gatgtaattg agggcgaaga
    45121 ctatactttt tgggggcaaa ttgtccagca ctccaagtat ggagaacaac tgcaaatcag
    45181 tcgttatgat cgcgcaaaac caactagtaa gggcttggtc aagtactttt caagtagcca
    45241 tttcaagggg attggtctca agacagctca gaaaatcgtg gatacctatg gcgaaaatac
    45301 cattgacgaa attttgcaac acccagaaaa gttagaaggc atcgcaggac tctctgccaa
    45361 aaatcgcgag gctttcgtct ccactctccg tctcaactac ggaacggaga tggttttgtc
    45421 caaactagcc aactacggca ttcccaacaa actagccttt cagattcaag acttttacaa
    45481 ggaagaaacc cttgatgtgg ttgaaaatta tccctaccag ctggttgagg atatcaaggg
    45541 tttgggcttt accattgctg accaactagc tgaggaacta ggcatcgaaa gtcaggctcc
    45601 tgaacgcttc cgcgccggtc tagttcacag tctttttcag gcctgtatgg aaacagggga
    45661 cacctatgtt gaagcacggg atttgctgga acaaaccctt actctccttg agtcttcccg
    45721 tcccgtggaa ctagacccca gccaagttgc ccaagagctc tcctacctga tcgaagaaga
    45781 caaggttcag cagattgata ccaagatctt tgacaacagc ctctttttcg ctgaggaagg
    45841 catccgcagt cacttggttc gtatccttga aaaaggaaaa cagaagagtc atgatttaga
    45901 aaccattcaa aaacatatca ctactatcga ggaagagctg ggaattgagt atgataacat
    45961 tcaaaaacag gctatctgtg atgctatcca gaataaggtc tttatcctga caggtgggcc
    46021 tggtactggt aagacaactg ttatcaatgg aatcatcgct gtttatgccc tgttagaggg
    46081 acttgacttc aggaagaaaa gcaatctgcc tattcttctt gctgctccaa ctggtcgagc
    46141 tgctcgtcgc atgaatgaat tgacaggttt gcctagcgcg accatacatc gccacttggg
    46201 aatgacaggt gacgatgata ccagtcatct ggaagattac ctagatgctg actttatcat
    46261 cgtggatgaa ttctctatgg tagatacttg gctggccaat caactcttct ccaatatctc
    46321 ttctaacagt aagatcctca tcgtaggtga cagtgatcag ctaccttctg tcagtcctgg
    46381 acaggttcta gcggatctgc ttcatattcc tttgattcct cagactcact tggaaaaaat
    46441 ttatcgacaa agcaaagaat caaccatcgt caccctagct agtcagattc gacagggcat
    46501 cttgccagct gatttcaccc aaaaaaaagc tgaccgttcc tactttgaaa ttgctagtgg
    46561 ccatattcct gccaccattg aaaaaatctt aggtgccgcc ctcagaaatg gtattcctgc
    46621 ccgtgatatc caagttctgg ctcctatgta ccgagggacg gcagggattg atgctatcaa
    46681 tcagctcatg caagacctgc tcaatccccc acaaaaagat caactcagtt ttgaagctcc
    46741 tcagtgccac tatcgtaagg gagacaaggt cattcatttg gttaacgatg ctgaaatcaa
    46801 tgtctttaat ggggatttag gagctatcac agacctgatt cctggtaaat acaccgaatc
    46861 gaaacaagac gagattgtca ttgattttga tggtaatgaa gtctcttacc cccgtaacga
    46921 atggtacaag attcgcttgg cctatgccat gagtattcat aagtctcagg gaagtgagtt
    46981 cccagttgtc atcctaccga ttactagtgc tagccgacgt atgctggagc gaaatctcat
    47041 ctacacagcc attacacgtg ccaaaagcaa actcatctta ctaggcgaat tacaagcctt
    47101 cgactatgct acccaacaca tcggaactgc ccgaaaaacc tatctgattg aacgcttcag
    47161 tgatctactg gagaatgttg aagaaaagca acaagctgtc tctgaaacag tcacatcaag
    47221 tgcctctgaa caatcctaca tcctaaccga agaaaactgg gacagcattc cagccatgat
    47281 tgggattaca gacacagacc tcaaagagat ttttggaaaa tagtgcatca gaaaaaccac
    47341 caattcaggt gggttttctg tttattaaga ttattttact gttgctgtgc ttgtaatcaa
    47401 ttcaacagct tttttgatag tgatatcatg tttcaacatg tcagctgaaa gcaagttttg
    47461 aacttgtgca acttccatgt tgtagtctgc tgccaattgc tcaacttctt tttggatttc
    47521 ttcttctgaa gcatcaaatc cttcagcttt ggcaactgct tcgataacaa ggttagtctt
    47581 agtacgtgac tcagcttctg cttggtattg gttgtgaagg tcttcttgag tagttccagt
    47641 aatttggaag tacatgtcag ggttgatccc ttgacgttgc aagttcccaa ggaattcatt
    47701 tactgaacgg tgaacttctt cgtggatcat ttcttctgga agttctacga tttcagcatt
    47761 ttctacagct gtatcaattg ctgcaccttc aactgcatct ttgtaagctt cttctttagc
    47821 agcagccaat tctttgcggt atttttcttt caagtcagca agtgtttcaa cttcttcatc
    47881 aatgtctttt gcaagttcat cgtcaagagc tggaacttct ttagctttta cttcgtggat
    47941 agttgtcacg aatttagctt ctttacctgc aaggtcttct gcttggtagt cttctgggaa
    48001 tgttacgata acatcaacgg tttcgccagc tgagtgacct accaattggt cttcgaaacc
    48061 agggatgaat tgacctgaac caagtccaag tgagaagttt tcaccttttc caccgtcaaa
    48121 ttcaacaccg tcgatagaac caacgaagtc gatcacaaca gtgtcgccgt cttcagcagc
    48181 agcttccttg ataaccaatt cagccaggtt gttgcgttca cgttcgatac gctcttcgac
    48241 atcagcgtca gttacttctt tttctacatc aactgatact tcaaggtttt tgtagtcacc
    48301 caattttact tcaggttttg taacaacttc agcagcgata acccagtctt gacctttttc
    48361 cattgaagtt acgtcaattt ttggttgggc aaccacttca agaccagcct cttttacagc
    48421 tgcttcataa gcgtttggca aaagagcgtt cataacgtct tggtaaagtg attcttcacc
    48481 aaatttttta tcgaagatag gacgtggaag gtgaccttta cggaaacctg gaacattaag
    48541 agatttcttc actgacttga agacacggtc caattctggt ttgatttggt cttgagagat
    48601 agtgaaagtc aagacaccac ggtttgtttc tttgttttca aatgatacag acattctgtc
    48661 atttctcctt aaaatttttt aaatacagtc tattataaca ttttctataa ataaaatcta
    48721 gactaatgca gacaattata gacaacaagc ctttttccta actaaaacac tcataaagta
    48781 tagacaattt tagactactt tggatatctt ttggttagtc attttccaaa actaatttat
    48841 ctaattttta agttatattt gacttcatct tctcagtaac atgagtataa acacttaaaa
    48901 tctttgtttc attagtataa tctacacgat ccattatcgc tgttataggt acttccaatt
    48961 cagcaagcaa acttatatgc gaatatctaa aaacatgagc agtcaataca aaatcatctt
    49021 tcttaatttc acttttccta aacctgtttt tcaaaaagta attgaaacaa gttatcatta
    49081 agggagaacc attatttgta aatatataat caccttcttc taaaagaaga tattctttta
    49141 aaatttctaa cactctatca ctaataccaa ttactctata tgaagctaaa cttttcggac
    49201 tatccaaaaa cacttcgtta ttggacgatt acattatagt aaaacgaaat aagaacagga
    49261 caaatcgatc aggacagtca aatcaatttc taacaatgtt ttagaagtag aggtgtacta
    49321 ttatagtttc aatctactat acaagacgaa attgaagaaa tctttccatt ataaaacgca
    49381 tattatcaag gtttttaaac acctaataat atgcgttttt tcctatttta aagactttta
    49441 tccacctatt atacaaagtt aagtatccat cacagtttac aattagcctt cattacctaa
    49501 cccattcacc atccttcaag agagtaacct ttaagaaccg aataaataaa tggcaaattt
    49561 cgttcattta atttaactgc actgttaatt tgattagctc catctcctaa agtatgcact
    49621 cctactacac ggtgactagc atcataaact gtagatccac tagacccctc taaagtatca
    49681 acttggtaat ccaagaacat gccatcatca cttaaaactt gttttttatc tgtatacatt
    49741 tgatgaactt taaaattata tgatggatag cctgtgatag tcacagttat tcctgtcaaa
    49801 tttttttgac tagtaggaag acccaaagtc cctaattttg caccaatggg ctcttctaga
    49861 attaataaag ccaagtcata ttcccttgca tccttagaat ttaaatttct aaattccttc
    49921 aaataacgaa cttcctttac tttgatcttt ccaaatggtt cttgacttgg actaacagtc
    49981 ggaagaacat aaatatcatc cgcttctttc ccatagtcat gtctgtagta gttgtgagcc
    50041 gctgtaatta acacattatc tttaataaaa ttcgcacttc ccctcccttc tacattcatt
    50101 ccatcggcta ctccataata cttagataaa accatagctg aagtcgaata cggatactgt
    50161 aaagtattat caattttaat caaatcatca ttaccgataa tacttctgat tgcttttggt
    50221 agtatgaacc atatgttggt gaaatctcag ataatgaaga atcattagat cctggacctt
    50281 tttctagtgt ctcacttacc tcatattctt cacccgtact agaaataaca ctcaaagcag
    50341 atactgtcga taactggcta gccaataaag tactcgcaat aattgaaata cccaattttt
    50401 tataaacagt tttcttcatt attgtatcct cctaatgtaa ttatagcgta ctattctaaa
    50461 tttcttaatc tactatagaa tcaagaaatc taccaccttc tttaaatacc ctccattatc
    50521 acataaacag gtaaactttt caattaatga ctgcgctttt caatcacgct agaggtactt
    50581 acttgcttct ttgatactaa gttcagccat tctttccttg tttttctcaa taaagcatgt
    50641 tacccaagtg ggattcgttt tggagtagtc tcgcagagtc cagccaatgg ctttattgat
    50701 aaaaaattct gtttggttca agttatgaag tagaatcttt tccattaatt gagtattggt
    50761 cttctctttt cttaacaact ggtggtcaat agcgacacgt ctcagccaga tattatctga
    50821 taggctccat tttatactca atgaaaatca aagagcaaac taggaagcta tctgcaacct
    50881 caaaacactg ttttgaggtt gcagatagag ctgacgtggt ttgaagagat tttcgaagag
    50941 tattaagatt atttcttcta gttcagggtg ttcatacacc aaactcccta ctactcgatc
    51001 taggatatct accgtgtccc accaggattt tgtcacgact aactgctcta gcttaggcaa
    51061 atcggtttcc tttagataag actgcattgc tttcaaatag ttagcagcca catattggta
    51121 ttttctaggc tccttttccc agcaagtgtc tgcaaaatcc caatcgataa tctttgtttt
    51181 tttcgcttct ggtaaatatt tttatagagt ttatttcttt caggcaccgc aatacctaga
    51241 aaagaaaatt gatggcgcat ataggcttcc atgggccttg cttttttaga gtcttttgct
    51301 gcttctagct cctcaagtaa atctgctaaa ctcatctaaa actcctcttg ccccaccaaa
    51361 tggtgctgaa aggcatagac agccgcctgg gtacgatcgc tgacttcaag tttggcaaga
    51421 atattggaca cgtgggtctt gaccgtcttg agagagataa agaggtcatc tgcgatgcgc
    51481 tgattttcgt agcccttggc gatgagttgg agaacatctc gctcacgcgc agtcaattct
    51541 tcatgaagtt ccatatgatt gcggtggtat tcaaccttct tgctaacctc ttgctcaatg
    51601 gccagctcgc cagcagctac cttactgacg gcatgaagca attcatctgc actagaagtc
    51661 ttgagcatat agcctttggc accagcatct aagactggca tgattttttc attgtccaaa
    51721 taagaggtca caatcaaaat cttggcttca ggccattctt taaggattgc taaggtcgcg
    51781 tcaatcccat tcatctcagg catgacaata tccatgacaa tgacatctgg acgcagttcc
    51841 aaggccaagt caatcccttg agacccgttg gacgcctcac ccacaacttc tacatcgtct
    51901 tggaggtcaa agtagctttt caagcccaaa cggaccattt catggtcatc tactagtaaa
    51961 attttcatct ttactccttt atcattcctt atctaacagg ggaatacgga tatcaactgc
    52021 cagcccttgc ttgggagctg ttaataactg aaccgtccct gccatatctt caacccgctc
    52081 cttgatattt cgcagtccat aactcaagtc gtctaagctt cctaaccgga aaccaatccc
    52141 attgtccacc accttcagtt gcaattcaac atctgtctga tagaggtaga catctaggca
    52201 agatgcctgg gcatggcgga gggtattgct aatcaactct tgcaggatac ggaagatatg
    52261 ctcctcgatt ttcttaggca atttcgtcat attctgcttg agactaaccc taagatcact
    52321 cttgtcctca agctctttta agagaatctg aatcccttct atcaagctct tctgctccag
    52381 ttcaactggt cgcaaatgca agagcaaaac ccgcaaatcc ttctgggcag tttctaaaat
    52441 agctgtgaca ctctgcaact gggtctgcat cttttctcta tccaatttca aagcctgctg
    52501 actgataccc gataaaataa tgtgggccgc aaacaactcc tgactgactg tatcgtgcaa
    52561 atcccgagca attcgcttcc gttccttctc gataatttcc tcttcctgat caaggctatg
    52621 attttcagct ttttgaagag cctctgtcaa aaggttaagt ttacctgata aggacttgaa
    52681 actggcatcc aaatctggat ctacaacctg aactacttct tgccctgcca ataaacgctt
    52741 gagattagcc tgcatttttc ttagagaaag ctcttcgatc cctcgccaaa acagggctaa
    52801 gagacaggtc atggacatgc tgaaaaccaa caataaaaag acaaattttt ctgttttttc
    52861 gacatcgtac aaaaagatag accagtcaaa atcaagtatt tccagcaagc tgtgggagaa
    52921 aaaaaagaca aataggaagg aggtgagagc aataatgaca taggcttgtt ttttcatcct
    52981 ctaaccacct ccacatcacc aatcatagtg gtcaagaaaa tcttgacact cttgttactc
    53041 ttgagatagt cttttgtttc ttgatgatag tgttcattgc ggagggctcg cttgggctgg
    53101 ttgaaaaaag tcaaatcccc atagagacag ttaacgctga gactgacttc cacatctaca
    53161 ggtacgatga ttttggtcgt tcctaccatc tttctgagga taatgacatt gtcatgattg
    53221 gttaagatga ctctctccag atgaatagtg tccttgccca tgaagcgaaa gagattgata
    53281 tcatcaaatt ggcaagtctg gtagcttgaa aaatgatgaa gatttccaaa ccaacgattt
    53341 ttctccttct taaccgtcac aacctcttca aaaaccaaat tggtctgctc tttttcctgg
    53401 ttcatcatcg ggtaaagaag aaagagacta tagataaccg caacaaaaat agctagaatc
    53461 acaaaaggat tgagcataac gatgaaaaag aagagaatgg ttgccgctac taaaagaaga
    53521 ttattcccct ctttaccagt atagtagcga atcaaaagca aaaagaggaa tagtatcagc
    53581 agaaaacgcg aaaaatgctc tgataccatc aaaatcagag ctcctgtcag aagacaggct
    53641 tcgataaata aaaagatttt aaattttctc ataggttcat cctctccctt ctattttatc
    53701 acaattcaaa aaagtcacct cagtctgagg atggaaaaaa aggcgctggt tacgcctttt
    53761 tcatctgatc ctttgcttct tttaattttc cataaagaag atagtctact ttttgtagat
    53821 ctgctatggt ggcacagtta agggaacaca taatcaagcg tagatctgct ttccagcctt
    53881 ggacaatgcc aatcacttct tcaactgtgt aggtttcaac caattccaga acggttcgtg
    53941 acaatcccac agccttagca ccaaaaacca agcacttaat catatccagc ggattccgaa
    54001 cccctccact aaccaagagt tcgaccttat ctttccattc ttgggcattg agaagggcct
    54061 gcatggtaga ctgaccccat tgattgaggt aatcacgctg gccactacga cggttttcga
    54121 tataggcaaa gctggtgcca ccacgacccg ataggtccac tgtacgaaca ccgaattcat
    54181 aggctctttc gattgtcttg gcatccattc caaagcccac ttccttgagg acaataggaa
    54241 cgggaatttg cttgctataa tctgctagat gcgattgcca gcttctaaac ttcctttctc
    54301 cctcgggcat gagtaattcc tgcatgacat tgacatgcac ttgcaataga acaggattca
    54361 tctcttctac agtctgaagt cctaactcga caggtttgtc caatccaata ttggttccaa
    54421 ggaggagatt gggatgacta gacttgacag aaaaagaatc atccgttgga tttttgaggg
    54481 ctgcgctata agaacccgtt acaaataaaa taccacagga ttccgccacc tgagccagct
    54541 tttgattgat ttctcttccc ttattacttc caccagtcat ggcattgata taaaaaggaa
    54601 agtcccactt tcgaccagca aactctgtcg aaagatcgat ttcatccaga ttgtaaagag
    54661 gcaaggaaga atgaatcagc tccacctcat caaagctatt ataggaactt ttctgctcaa
    54721 gggcatagag gatatgctcg tccttacgat ttgtcgtcat gtcctatcct ttcttgatat
    54781 aagagctcaa tccccagatc ggcccaacga ttttttaagg ttttggttga ttgcgcatca
    54841 aaactcaggg cgatgccaca gtcaccacca ccagcaccac tactcttggc aacggcctgc
    54901 aaatcttgac tggcttcttt caactgtcta agcaaaggcg tgtaaatatc tgtactcaag
    54961 ccttctaaaa gcttgctggc tacttctact tgctcgataa tcttttctga tttcccctgt
    55021 tccaaggctt cgaccaaaga aaccaccgtt tcttttgagg aacttaaaaa attttgattg
    55081 atattttgct tgatttgctg gaccatgtga ctcgatacag ccacttcctt ggtccatccc
    55141 actaagaaat cacattctaa agttggtttc acttgtgaaa ttgaaaagcc ccaatcacgc
    55201 tccagaactg tcgccaagtt ttcttcttct aaccaagcag ccaccttctg gcgatcaaat
    55261 gactggtaga gaaccaaatc ctctgccaca atacaggcaa ggtcgcccat ggaaccattg
    55321 tctcctcgct tgagcaagac agcgctagtc agcttgaaca agagctcctg atcaacagaa
    55381 acatcataca gagccagtaa agccttgaca accaagacaa cgacgctgcc actagaacct
    55441 agaccaaact ttttcccttc tcgttccatt ttgccacaga tttctaggga aaaagatctt
    55501 aaattctgac cgcgaacagc gaggaagtct cccatcaaag caatcgtttc ttgaatcaag
    55561 ctgtagtcag gattgggcgt taagtccact gcgaaatcaa acatatctga atagatacgg
    55621 tagctgtcag aaaaagcaat ctcagccctc atatagatgg gaatatcctt tatcaaagct
    55681 aactgccctg gctctaaaat agcatattca cctgcccaat agagttttcc gcaagtttta
    55741 acagcaatca tcttgactca aatcctttgt ttttgacaca atcaagcgat aacgctgacc
    55801 gaaaatttct gacaaatgct ccaagtcttt ctcctgacaa aagaccttaa cattgggacc
    55861 agcatccatg gtaaagtagc aggcctctcc tttctcacga agctggcgaa caaagtccat
    55921 agcctcataa gaggcatccg tcagataaga aaaggctgga ctagcagtct ttgtcgtagc
    55981 atgcatagcc agggcatttt tctccgttaa ttctccaatc ttggcaaaat cattttcctt
    56041 gagataaatc agcatatcct gatagtcctt ctcagactga cgaacccagt cgtcaaaagt
    56101 cgtcgaggtt tccacacaaa gtttcatccc gtcacggcta gagattggtt ttttcttgtc
    56161 ctctagcacc aacataatca tagctagttt caagtctgtc tctacagagt aaatttctcc
    56221 actatcctta tcccaggctc ctagcggtcc ataaaaactc cgagaagaag agcctgaggc
    56281 aaacttggct tcctgcgcta actgacttct atccaatcca agcttgaaat aagcattaca
    56341 agccttgacc agggcggaca aaccactaga acttgaggac aggcccgctg cagtaggcat
    56401 attgttttga gtatcgatac ggacaaagcc ctcaccagct ggacgataac ggtcaataat
    56461 cttactcatc ttggcatgct cgacctcatt ttgtagctga ccattgatgt aaaattcgtc
    56521 agctattaca ttggctggta aaggcgacaa ggtcgtctct gtatacatat tttccaaagt
    56581 tagagaaata ctgctagtag caggcaccat ctctttttct tttttctttc cccaatattt
    56641 gataatagca atatttgcgt aggaacgtac tgtcacaggc tctctatcca tgtctgaaca
    56701 gctcctttct cttctaatct ttctgctagt tcttgtgcgt gtgtcaaatt ggttaccaag
    56761 gctatgatac aacctcctag cccaccaccg ctcatcttgg cacccagagc accatggcta
    56821 agagtcgttt caaccaaaaa gtctgcctca gggctactga ctccaatttc ttttaaatgt
    56881 aaatgcgctt gactgaggat ttgtcccagt ccttcagcat ctttttgtga aatcgcaact
    56941 tctgcttgct gggttaattc tcccaaggca tgcaaaaacg gtagggcatc cttgccctta
    57001 ttttgaacca cttggatggc ttcacgagta tgaccataaa cacccgtatc ggcaatcacc
    57061 aaataggcgg ataaatccat ctcaagttct gtaaatccta cgttcttgat aaagcgaata
    57121 ggttggtcac tgagacaggt cttagcatcc aaaccactag gattcatatg ggcaatcatc
    57181 tcagctcgat tgaccaagat ttctagtaca tcatgaggca gatcagcctg atagtagtca
    57241 aataccgcac gaatggccgc tatgctgata gccgctgacg aacccatccc ccgtttctca
    57301 gggatagccg agtcaatctc acaacgaatg caggcttctg tgatatccaa atactccagt
    57361 gaggcataaa ccgccatgga caaggtatcc tcctcataaa ggcgccaagg actctctgca
    57421 ggaactacct tacaggtcac ctccacctcc aaaagaggca gggaaatggc aggataaccg
    57481 taaacgaccg catgttcccc tattaaaatt atcttactat gtgcctgacc gacaccaact
    57541 ttttttgtca ttttttcctt ttactagacg aaaaaacgtc ttatttttca tacaagtatt
    57601 aattctttcc tatctatttt attatatttt cacaaaaaaa gcgattgttt ccattcacaa
    57661 tcgcttcttt cattattgaa cccattcgcc attatagttg acagaatagc catctacggt
    57721 cgtattcact gccaaggcac ctgagctata agcgtagtac catctgccat tgacctggaa
    57781 ccaacctgtc gtcatagaac gacgaaagaa actccatacc gttaagtaaa gaggaaagtc
    57841 gtgagggatc atgcgccatt gacaacctgt tttagtgacg tacaaagtct cattaacaag
    57901 tactcgtttc ggccatttat aggtgcggtg tttggagaaa tagggttcaa tcttagccca
    57961 ttcttgatcg tttaaatcag tatcatatgc tttgcgtgtc ataactctag tttaacattt
    58021 tttgtgaata caagttctaa ataatcgacc acgaaaattt cttaagtgga aaacgcctta
    58081 tgaagtatgc tacgggaaac ttatgcactt aatttgacaa ttcaagatgt aaaaatatat
    58141 actatagtag attgaaacta gaatagtaca cctctacttc taaaacattt ttagaaatcg
    58201 atttgactgt cctgatcgat ttgtcctgtt attattttat tttactataa tatttgacaa
    58261 gttatcctaa aagtattatt atgttgttgt gttatagatt gattgaatct aactaaagga
    58321 tcctattcaa ttactagaac tatcacatac tcaaggtcag ctcacagatg agcaactatt
    58381 ttggttacaa tgtctactaa atttaagtca aacaaataat ttagtcaaaa ttaaaaaaat
    58441 agaggaacat aaatatgatt acaaaacaga atgtaatagt gttctacgat ttttactaga
    58501 taaaactgta aattctgaag gaaggatcac ttcttcaaca gaatttggaa atttcgtaag
    58561 taatttatca ttccaacacg gaatagctgg actactgttt cctctaaata aattgtaccc
    58621 cccagaactg gattctaaaa tactctctat catcaagaag gcagtgacaa ttagaacgac
    58681 acacatatga atatcaatac tcactgctat ttggtgatgc aggctatcta tggttactcc
    58741 tacatttatt ttctatcagt aaaaatcaat actatctaca attagcaaac gtcaccgcta
    58801 agaaattaat agagaattat gatactctag aagaaataga ctttgcattg ggaaaatctg
    58861 gtgtcctatt atcattaata aaatactatc aatttaccaa tgacaatact cttaaaactt
    58921 tcatccacaa tagtatatgg ggaaatttat cattatttcc tacaaagaga tacagccaaa
    58981 gaaagcattt tagactatag ctttgctcat ggatattgtg aaattgcata tgctttattt
    59041 gcctattcta aagtcttaga accttctatg ttctataatg atctccatac attccatgct
    59101 gaattaaaaa aattattaga aaaagttact tctaatactg aaaatttagg aaatttacaa
    59161 ctttcttggt gcgaaggaat ttccggaata atcttatatc tttgtatgta cgattgtgac
    59221 ggaaacaaag atattattag taaatatcaa gaatttgttt ttaaccatca tctaaaaatg
    59281 atgacaggat attgccacgg aataactagc ttactacaaa ccactgtcta caatcaaaac
    59341 aaattactga tgaaaaaaat ccaacaggta attttagcat gttctgaacg agatgatcac
    59401 ggtttactga tgtttcaagg agatagtggt aaagcagatt tgtttgactt cggaatagga
    59461 agcagggggt atattggtgt ctattaaata ataaattccc attcgatgtg caaacataag
    59521 gagaaatgta tgaaattatt ttggacaaac aacatatata gacagttgct gctaaacagc
    59581 tgtttttcat cattcggcga cagtattttc tacctcgcca ttatcaatta tgtggctcag
    59641 tacaatttcg ctccgctagc gattttactg atttccattt cagagatggt tcccctacta
    59701 tcgcaactct ttctcgggat tctaggagat tttcaagaaa atagagtcaa acacgcactc
    59761 tgtattgcca aaatcaaaat cctgctctac gctattttga cagtatttct cgtcttgtcg
    59821 cccttttcat tagtttcagt cattatgatt gtcatcatca acctcatctc tgacaccttg
    59881 agctacctgt ctgcctacat gatgaacgcc ctctacatca gtgtaattaa ggatgacctg
    59941 catgatgcca tggggttcag gcagtctctg atgagggttg tccacattgt cgccaatctg
    60001 gctggcgcat tccttatcaa tgttataagt attcaaacta tttcccttat caacactctg
    60061 acttttgtca ttgccttttt gggcctgtat gttattcgac ataccttgta tgaggttgaa
    60121 aaaaggattg aaatgtcaca tacagcactg agttttaaga aatattttca acatcttaaa
    60181 cagtcgctgg ctgtgctcct gaggttaaaa gataccgtca tactactgtt tctgacgacc
    60241 agtatgattg ccatcttgga tgtgtcccct cggctgattg ccctccgctt catccaacag
    60301 acactagcac aactgagcat tgggcaactc ttcgccctgc tctccatcat catgtcttgt
    60361 ggagctatcc ttggcaatat gaccagcagt aatctattta aaaatatccg tttcacgcac
    60421 ctcttggttt tctgtgagat ttccctattg gctctaataa ctagtatcct ttgtcaagcc
    60481 tatatcgtaa ttttcgtgac cagtttcatc agttctacga ttatcggcat tctcagccct
    60541 cgcctacaag cagctgtctt tgcccatatc cccagtgaca agatggggac ggtgggctct
    60601 gctctgagca cagtagacat tctcgccccg tccctgctct ccctattagc cctatccata
    60661 gcatcgggcg tttcggtgca gttagcattg atatttttgt atcttatttt gattgctctt
    60721 atcttttgtc aatggttagt caagttcaac actcataact aacgaaaaag catgtgtaga
    60781 tttcacatgc ttttaatctc cccaatcgtc aggtcaagta caacaaagtc acttctttga
    60841 ttaagcgagt gttctaatat aattataagc gccctgtcat taccgaaccc attcgccatt
    60901 atagttgaca gaatagccat ctacggtcgt attcactgcc aaagcacctg agctataagc
    60961 atagtaccag ttgccattga cctggaacca acctgtcttc atgtctccat tacctgcatt
    61021 taggtagtac caagttgaac catcttgata ccaaccagtt gccatagctc ctgatgaacg
    61081 gagatagtac catttgttcc caaggttttg ccaacctgtt ttcatatcgc catttggctg
    61141 gtctaaataa taccaagtgg taccttcctg ataccagcca gtggccattg ctcctgagga
    61201 acggaggtag taccatggag caggtttgct tctatcaatg tcaatagtaa catgaaaatc
    61261 ttgagtccaa cccttagcaa cttcaccaat tggtagtgga ttgtaagaat catcaccaaa
    61321 atttcctagc ttatttaaat aataccaatt gccgtcttca taaatccagc ctgtctttac
    61381 agcataatta ttatcaaaat aataagttct cttttcagca gatagaggat attgttcacc
    61441 gtatactttt cctgtatttt cagacgtttt tgcctctagt acttgtttat ctgtttgttc
    61501 tagcaaagca ccatcttgtc caaaatagta ccacttctcc tgaaggccaa tttcgaagac
    61561 tggacgatta tcaaataaat catcacgata acctgttcca ggaatttcta agtattgcca
    61621 accgacaacc atctctccaa tatcaccaaa atagtaagtt ttaccgtcta ttttatgcca
    61681 atagattgct ttatgatcat cttttacata atattttcta ttatccttat caacaaatcg
    61741 gccacctgtg gtattcgcaa ataccgtatt tgtagctagc aaaccaaaga aaaagactgc
    61801 tagtagaact tgcatcattt ttttcaaaag tttcatttat atatcctcct aaaacgattg
    61861 tagcaaagac acgactgcat gtcaatatat aaaaactcct caaaaaagca gttacacaac
    61921 tgcaactgct tttctattct tgcatggtgt aaccaacacc acgcacggtt ttaatgtagc
    61981 ttttttgtcc tttaacatca agcttgctcc gtagatagcg gatatagaca tctacgatat
    62041 ttgtctcggt cgcactttca tacttccaaa cactttccaa caattgctca cgagtcaata
    62101 ctttcttgct tcccataagt gtcgccaaaa ggtcatactc acggcgggtc agagcaatca
    62161 tctcttcacc acgataaacc gtgtgatgtt caacatctat cctaagattg cggtaggtcc
    62221 ttggaacttt catcagactg cagtgttgat caatgaagtc ccgacctcgg aagatcgccg
    62281 aaatacgcgc taccagattt tcgataaaga ctggcttata gatgtatgaa actgcaaaac
    62341 gctgaacaac ttccagctct tcttgcaagt cttcccaatg atctaaaatc atgatgactg
    62401 aggcaggttt agttcgactc aatttttctg caaaatcctg agccatcata tctcccagat
    62461 taacgttcaa taaaatcaaa tcatagtctg tctgaagagc catggaaagg gctttttgcc
    62521 cctcctctac cagatcaacc cgatactgct ctttctggag ttccaaactt aaaaaatgag
    62581 ctagatttcg ttctttctca agtaataaaa tccgtttccc catggctgac ctacttattt
    62641 ttcgtcatac caagagtagt ggaaggttcc ttctttgtct ttacgttggt aagtgtgagc
    62701 accaaagtag tcacgttgtg cttggatcaa gttagccgga aggtcagctg aacggtagct
    62761 atcaaagtaa gtaatagctg ctgagaaagt tggcactggc acaccagctt gaaccgcaag
    62821 agctacgata tcacgcactg cttgttgata cttagcagta acatccaaga agtactcgtc
    62881 caaaagaagg ttggcaagat ctgcatcgcg gttgtaagca tctgtaatct tttgcaagaa
    62941 acgagaacgg atgatacagc catcacgcca gatagatgcg atatctgcaa atggcaagtt
    63001 ccagttgttt tctttagagg ctacacgcaa ttgagcaaat ccttgtgcgt atgaaatgat
    63061 ttttgagaag taaagggctt gacggatttt ttcaatcaat tcagccttgt ctccttcaaa
    63121 gttgaaggca gctggttttg gaagcacctt gctagcatgt acacgttctt ctttgtaagt
    63181 tgaaatgtag cgtgcaaaca ctgactcagt aatcagtgac aatggtacac caaggtcaag
    63241 agatgattgg ctcgtccatt taccagttcc cttgttacct gcagcatcaa ggatgtagtc
    63301 tacgattggt ccatcttggt cttcatcgtc tttacggctc aagatatcag ctgtgatttc
    63361 gatcaagtag ctatccaatt cacccttgtt ccactcagta aagatttcag ccatatcctc
    63421 tgcagaaagg cctagcaagt gttgcatcaa gtcatagctt tctgcgatca attgcatatc
    63481 accgtactcg ataccgttgt gaaccatttt cacatagtga ccagctccat caggaccgat
    63541 ataagtcaca catggtttgc catcttctgg tgctttagct gagatttctt caagaacatc
    63601 cgaaaccaat tcgtaggcct ctttttgtcc accaggcatg atagaaggac cttcaagggc
    63661 acctttttca ccaccagaaa ctccagtacc gataaagttg atacctgagt ttgccaattc
    63721 ttcattacga cggatggtat ctttgtagaa agtgtttcct ccgtcaatca agatatcacc
    63781 tttgtcaagg tgtggaagaa gggcttggat agtagcatct gtaccaggtc cagcttgaac
    63841 catcagcatg atacgacgag gtttttcgat tgagtttaca aaactttcaa cgtcatagct
    63901 tggtacaaaa ttcttttcag gatggcaagc aatcacatct tccgtttttt ctttactacg
    63961 gttgtagata gcaactgtgt aaccacgtga ttcaatatta agggcaaggt tacgacccat
    64021 tacggccata cctacgacac caaagttagc ttttgtcatt tgacactcct cttgtttcat
    64081 ttgttttatt ttatcatttt tacttttgaa aagaaagaat tttgtaacga ctgcttagta
    64141 gtccaagtca tccgcatgac cagcgccatt tccgacaaag tagcctgtct tacagttaag
    64201 ggtaaagaga taggttccat ctggcttata gaggttgtaa taaccattgc cgttaacgat
    64261 attgacacgt tcaaggatat attggtctcc agtgatatag ccacgtgaac gtgaagttgc
    64321 tagaatttgt tccaaaacac catccgcaaa atcccaggca gagttattac tatcatcaat
    64381 agcagactga ttataggcaa cacgactggc acttctttga acagcaaccc ctgcactcga
    64441 gagacccata ttgacttcac tgcgactact tctagtctca tttgaactac ttggttttgg
    64501 ctcactagtc gtatttgaac ttgcttgact tgaacttgag ctgctagttt gacttgaact
    64561 tgagctagaa gtacttgttt gctggctctt accaagactg atagccttat ctagcacttt
    64621 atcaagctcc gtatttccag ttttaatatc cgtaaattta gcatccgatt tggctttggc
    64681 attggtatcc aacacaccat ccacaatagc tggtttttca aattgtgcat tgacatcttg
    64741 aatggccttg atttgcgtta ctagactatc atatttagat ttggcaagcg tatgttcacg
    64801 actaccttcc agcttatcaa gtaaagtctt gagttgactc agtttatcaa actggctatt
    64861 tttcaaagcc gttttattgc tatttgtgta aaaggcgtca taaagtgtat taaaatcatc
    64921 cacatccgat tgattggctg tagttgattg agaagtttca atttccttgg tcgaacgagc
    64981 cacttgacga tagacataat aagcactgac acaaataatt actgatacaa gcgccaaaac
    65041 ggtcaaaata aagccttttt tacttttctt ttctgagtcc tcttgatcca gacgagaaag
    65101 gttttgctcc tcttccactt cttcagtcat ttctgttgga ttttcatcat ctagcaatag
    65161 aggatccaag ccttgctcct catcgtccag aggcaagggt agtaagatgt cttcagaaga
    65221 tggaacttcc tccgaagaag cttctgactt ctctacagcc tcacgcatct cttgaattaa
    65281 atcatccaga ctctgagttt caacgaactc ctcttttttg tattgacgag tcgcaaactt
    65341 atccgcctca atttcatctc tgtgttgctt aacatacttg tccaaaatgg aatcctcagg
    65401 caagactcct gcttccactt cttcattttt acgaatagct tgaccaactg ttagctcttt
    65461 tgcttcatca aaatcaaatt gcggttcttg accttctttt ttatgacgat ttcgtctttt
    65521 tttactcatg agtatccctt tctattttac ctcttgccgt ttgacacgct gaccaaaata
    65581 ttgatataga tccactttca aggttccgtt gtataactta cgcttcttat ctgcttggct
    65641 accatacttg ctttcaaaag cttcatcact agtcaggata aatttgctcc aagttttcag
    65701 cggtgcaaat acttgcccca tctcagcata gagcttggtc actcctgcat catctgacaa
    65761 acgttcacca taaggcggat tggaaatgat tactccattg attttatcgg aacgtaaatc
    65821 ctgcacgcgc atctgcttaa aagtaatatc tcctgcaaca ccagctgcct gagcattggc
    65881 cttagcaatt tccaccatgc gagcatcaat atcacagccc atgatatcca actcaagctt
    65941 acgttctact tttttagccg cttctgtgcg cacttcttga atcaagcgat cgctgatcca
    66001 gttccattcc tcaaatgcaa aagagcgacg aagacctggc gccatctttc tagcaatcat
    66061 aactgcctca atacagaaag tccccgaacc acaggtcgga tcaatcaaag gcttgtctgg
    66121 ataccagtta gaaagttgta aaatggctgc tgccatattt tccttgatag gagcgccacc
    66181 tttttcggta cgataaccac gtttaaagag gctagacccg gtcgtatcaa tcatgacagt
    66241 tgccacatct ttgagaatag agacctcaat cttaaactct gggccattct ccatcagagg
    66301 aaccccttct gggcgagcat agtgtttctg caatttcttg acaacagctt tcttagaaat
    66361 agcctgaaca ctgggctcat tgtgaagttt ggacttaaca catttagctt ttgaaatcgg
    66421 taaccgagct ccaagtggta aataattttc ccaatctaaa gcgaaaactc cctgaaatag
    66481 ctcttcaaaa gtcttagctg ggaacgttcc tacgataatt ttgatacgat ctgctgcccg
    66541 aagccaaagg ttggtttcga taatagctct cacgtctcct tgaaaacgaa cacgtccatt
    66601 ttcaacctga caatcgtagc ccaactctcg cacttcacga ccaacgacag cctcaagccc
    66661 tgctgccaca gttgcaatta aattaaattc ttttttcatg ttacagtctt gcaagacctt
    66721 tctatatgtc cactttaaaa aatgaggttg agaaaatttc tcagccccaa cctatatgca
    66781 attttctata agccatgttt tgttccagaa gtgactagga ccacttcctt cgataatcat
    66841 ctgtctacca ctaacagctc tagctgatag cagtcagaat actacgttcg tttccgcata
    66901 ctccatgccc cgaccaaaat ttgggttgct agcttgaggg gtttaccgcg ttccactctc
    66961 tctgtttcca gaaagactcc gtcactgtgg cactttcaag cctactctgg cctatccaag
    67021 gacttagcca tttcaactgc cgtaacgatt tctcgtccct aggcttatgg tttcgcctag
    67081 cacaaacact acaggcatca cagcctgtgc tagcatggac tttcctcatg agaagcaatt
    67141 ctcctcacgc gattatccaa aaattgcaca tctcaaataa ctacttaaaa atctgagtta
    67201 tctaaaattt gtttaccaaa aacttctttt tccaatctat tcaggcgttt caaaatatca
    67261 aaattcgtca tagaacttgt aattgccgct tcaaggggtt ctgcttgaac tggtgaaggt
    67321 ttcggtttac gagttaattc ttccttcaaa tccgcaattt cctgacgaag tgacttgacc
    67381 aaggcagcat aggtttcata gtccttgatg acatcgtcta aaaactcgtc aacttctact
    67441 ttattatagc cacggacttc acgtccaaac tcttgttcaa aaatatcttt cgctgaaaaa
    67501 ataatacttg ccatgtctct ctccattctc gcttgctagt attattatat aaaaaaaggc
    67561 aaacaaaaat caaggtcaaa gcttcaattt tcggaaaaat tttcagcaag ttcatttaat
    67621 tgatcaaatg ttaatctctt tataaaatag tcctcttgat ttttcatctt ttggtaaaaa
    67681 taagctagtt ttgtttcatt ttcttcatca taaaaaagat aggaactagt cgtgttttcc
    67741 agcaaaaact gctggtaatc tcttaactgc cccttgtgtt catagcgagg ataagcatat
    67801 ttgacaaagt ctacctgctt aaagcgactc agtttcatct gattgccttc attccaattt
    67861 tccccatggg tttcaaaagc aaaaatggtg gccaactgga aaccgtattc ggttttcatc
    67921 tcctgagcaa cctctaaaac ccaatattca aaacccaaac tccctgtaaa cacaagccaa
    67981 gacaccccat ctgctgccat agcctctaaa tctttacgta tcgctttttt aatcaattta
    68041 agacgaggat ccttatcaga aaataaaccc aaatcaaaag cagaatagcc taaaaccaaa
    68101 gctgtagcca tttttaaccc tttctgtgca aattatggta taataaagtg atgttattgt
    68161 accaataagg agaattatga tcaactatcc acataaagtt tcatcacaaa aaagacaaac
    68221 atctctttct caacccaaaa atttcgcaaa tcgaggaatg tcttttgaaa agatgatcaa
    68281 tgctaccaac gactactatt tgtctcaggg cttggctgtt atacataaga aaccaactcc
    68341 tattcaaatc gtacaagtgg actatccaca acgaagtcgt gccaagattg ttgaagccta
    68401 ttttcgacaa gcttcaacga cggactattc tggcgtttat aatggatatt acatcgactt
    68461 tgaagtcaag gaaacaaaac aaaaacgtgc gattccgatg aaaaattttc atccacatca
    68521 gattcagcat atggaacaag tccttgccca acaaggaatc tgctttgtcc ttcttcactt
    68581 ttcttctcag caagaaacct acttattgcc ggcattcgat ttgattcgct tctatcatca
    68641 agataaggga caaaaatcaa tgccacttga atatattcga gaatatggat atgaaatcaa
    68701 ggctggtgcc ttccctcaaa ttccttatct caatgttatc aaagaacatt tattaggtgg
    68761 taaaacaaga tgaacaaacc aacgattctg cgcctaatca agtatctgag cattagcttc
    68821 ttaagcttgg ttatcgcagc cattgtctta ggcggaggag tttttttcta ctacgttagc
    68881 aaggctccta gcctatccga gagtaaacta gttgcaacaa cttctagtaa aatctacgac
    68941 aataaaaatc aactcattgc tgacttgggt tctgaacgcc gcgtcaatgc ccaagctaat
    69001 gatattccca cagatttggt taaagcaatc gtttctatcg aagaccatcg cttcttcgac
    69061 cacaggggga ttgataccat ccgtatcctg ggagctttct tgcgcaatct gcaaagcaat
    69121 tccctccaag gtggatcaac tctcactcaa cagttgatta agttgactta cttttcaact
    69181 tcgacttccg accagactat ttctcgtaag gctcaggaag cttggttagc gattcagtta
    69241 gaacaaaaag caaccaagca agaaatcttg acctactata taaataaggt ctacatgtct
    69301 aatgggaact atggaatgca gacagcagct caaaactact atggtaaaga cctcaataat
    69361 ttaagtttac ctcagttagc cttgctggct ggaatgcctc aggcaccaaa ccaatatgac
    69421 ccctattcac atccagaagc agcccaagac cgccgaaact tggtcttatc tgaaatgaaa
    69481 aatcaaggct acatctctgc tgaacagtat gagaaagcag tcaatacacc aattactgat
    69541 ggactacaaa gtctcaaatc agcaagtaat taccctgctt acatggataa ttacctcaag
    69601 gaagtcatca atcaagttga agaagaaaca ggctataacc tgctcacaac tgggatggat
    69661 gtctacacaa atgtagacca agaagctcaa aaacatctgt gggatattta caatacagac
    69721 gaatacgttg cctatccaga cgatgaattg caagtcgctt ctaccattgt tgatgtttct
    69781 aacggtaaag tcattgccca gctaggagca cgccatcagt caagtaatgt ttccttcgga
    69841 attaaccaag cagtagaaac aaaccgcgac tggggatcaa ctatgaaacc gatcacagac
    69901 tatgctcctg ccttggagta cggtatctac gattcaactg ctactatcgt tcacgatgag
    69961 ccctataact accctgggac aaatacccct gtttataact gggatagggg ctactttggc
    70021 aacatcacct tgcaatacgc cctgcaacaa tcgcgaaacg tcccagccgt ggaaactcta
    70081 aacaaggtcg gactcaaccg cgccaagact ttcctaaatg gtctcggaat cgactaccca
    70141 agtattcact actcaaatgc catttcaagt aacacaaccg aatcagacaa aaaatatgga
    70201 gcaagtagtg aaaagatggc tgctgcttac gctgcctttg caaatggtgg aacttactat
    70261 aaaccaatgt atatccataa agtcgtcttt agtgatggga gtgaaaaaga gttctctaat
    70321 gtcggaactc gtgccatgaa ggaaacgaca gcctatatga tgaccgacat gatgaaaaca
    70381 gtcttgactt atggaactgg acgaaatgcc tatcttgctt ggctccctca ggctggtaaa
    70441 acaggaacct ctaactatac agacgaggaa attgaaaacc acatcaagac ctctcaattt
    70501 gtagcacctg atgaactatt tgctggctat acgcgtaaat attcaatggc tgtatggaca
    70561 ggctattcta accgtctgac accacttgta ggcaatggcc ttacggtcgc tgccaaagtt
    70621 taccgctcta tgatgaccta cctgtctgaa ggaagcaatc cagaggattg gaatatacca
    70681 gaggggctct acagaaatgg agaattcgta tttaaaaatg gtgctcgttc tacgtggagc
    70741 tcacctgctc cacaacaacc cccatcaact gaaagttcaa gctcatcatc agatagttca
    70801 acttcacagt ctagctcaac cactccaagc acaaataata gtacgactac caatcctaac
    70861 aataatacgc aacaatcaaa tacaacccct gatcaacaaa atcagaatcc tcaaccagca
    70921 caaccataac atttatcacc cagatttttc tgggtgattt tgtcatagca ctattgtatt
    70981 tatgtgctta acaaaagcct gagaagatgt cttctcaggc tttttctgta ctataaacct
    71041 cattggaaaa gatagagact gcttccgtaa tcttgttaag aggttttact aaatactagt
    71101 ctttcttcgt ttttactaca aagagagcag atagggctag actaacactt gctaggaaga
    71161 gggctgtgtc agattgactc tcacctgttg ctggcaagat ttgttcaggt gtttctggtc
    71221 tagctatttc ttgcttataa tctggcgtct taccttgatc ggaaactaaa gagctaagtt
    71281 taaactcagg tttctctaca gttggagcat ctggtttcgt agcagaatct tttaattggt
    71341 tgagataatc tgcaaagtat tccaccattc tttccgtcaa gagatggtta tccgtcgcat
    71401 atttcatgct tgcctgaacg ctagctactt cctcttgatt gtctttgtct gttaatttct
    71461 gagctttagc caaagctgct tcatagcctg acaagtcaag aggtgtttct gctacctgtg
    71521 gacgagtaaa gatgagttcc gctgcagatt ggtatttatc gccaccatct ccgtaagtct
    71581 tagtacctgt aaggacaatt ttcttagcct taattgtctt accaaaatca atgtcttttg
    71641 gcttattgtt atctggccaa tcagttgcag taaaggtatg ctccttgcca gactcatctg
    71701 tcacaacaag tttcacatca cgcaagttac catttgaacc tgatccacgt ggaacgtaac
    71761 gaagtccagt gatttcagtt ggttctttca agaccatggt tgcaggcttg cctacatctc
    71821 caccattcca agatgtatgc cataaactag ataagtttcc atcaaaggca tttgcaagac
    71881 cttcttgagc ctgagcagga gctgtaagac ttgcaaagtc atctgctacc aaagccgttt
    71941 tcttctgaac caaagcattc ttcaaggctt caatcttggc aatctctgca cgcgcttctt
    72001 ccacactgat atcatcatcg gcctgactaa ggttaaagac cgcctctttc aaagcatcca
    72061 tagactcttt ggtgtagtta gtcatggcaa ccgttggcaa gtagttcttc agagcatttt
    72121 ctgtcaacat cttacctgtt agggtaattt cttcgatttg aagattatcc atcatgaagt
    72181 cgttataacc acggaagttg gcatttccac cagaatcacc acgagtatta cttgcattgc
    72241 cagttgagta gatacctacc caagtatccc ctgtttctgc acctgtcaca aggaaggttg
    72301 ccttcttggc tttcttagaa tctgtccaag tatttggcaa ttcatgcatt tccaagttgc
    72361 ttgcttgagt gccacgacga cctgactgga attctccctt accgactaca aaagcatagg
    72421 tattgtctga acctgcttcg tattcaaagg ttacacggta ggtcttacct gcttcaaaac
    72481 ggaagttttg tgggatggtt tggtaaacca agttacgacg gctcactagt ccatttgtct
    72541 tgagtgacca atttccttcg ataacatcat cgactttctt accgttccaa ccacgttgtg
    72601 tatatggatc gtgtttttca gacaagtgag tgcggttgtc ttcgacacct tcgacaccac
    72661 ccactacaaa tgggaagatt ccttgagcta cattttcaaa gtcttgcttg aaggttcctt
    72721 gacctgtatc gtgcttgtct ccatacatgc ttgaattgtt ttcaaaggta cgaatttcat
    72781 caaagtaagt tgcttgatca ccagcttcac gactcaatgt cagagtaaca tttgagacgt
    72841 ccgatcctgt tgtaaagaag gcgtacatgt tttggaagta acttgtatcg ttaactgtag
    72901 cattgttacg acgtgtattg tgggcgtagg cttttacata gttgagggcg agagacttat
    72961 tggtataagt agtcacttct ttttcaccag tattcacagt gatacttgcc ttggcattac
    73021 tacggttatc gacaccgaca taaacggcat acttggtatt tggtttcaag ccagttaatt
    73081 tctgagtgag actaactttt tctttgtttc cttgaatacg aagcatatcg tttgcccctt
    73141 gagacttgac aatttctgcc ttagaagcat cgcctgaaat ggtccaatgt ttcaaggtac
    73201 cactgttaaa tccttggtca tagatgtgca tgccttcact ccatgacatt tcaggattgg
    73261 tttgttttga acgatagaga acgtatggtt gatttgctag aagatctagg gtaattttac
    73321 catcttttac agttagttct tgctcttctg tcttaccttg gtcagttagc ttgtaaaggt
    73381 aaaccttgct ctttgcccaa tcgcttggaa gggtccaagt tgttgcaccg gcctgcgtat
    73441 tgaagtagta catcttttcc ttatcagtag aaagtttctt accatttgca tcccagttcc
    73501 aaggagtcaa gtaagctgaa ccatcttgga tgacacgtcc gttgagagtt actgtacgtt
    73561 cgcgatattg tggactattg acatcatttg acttacgagt tacaactact ttattattgt
    73621 cagcatctac caattccact cgcatttctg gagtccattt ataggtacta ccgttatcgg
    73681 tcatagtcac cggtgtacca ttttcccatt tacttacagt gaagtgttgg aagtacttag
    73741 tcatgacgtc atgggcaaat aagttggtta catagccatt gtagtcactt cttccctgcc
    73801 agccttcaaa gtctttcatg ctgtagccac ctagcagtgg atagttggct gcaccaccat
    73861 aacttctgta gtccccaacc caagcatctt tttggtggtt acggataaag cgggtgatgg
    73921 cactgttgat acctttattg gtgtagccac cgtaggtcaa gtcagctgcc cagtgatgga
    73981 aggtagagtc gtactcacca ccatggcccc actcgatcgc aaagcgccag ccttgtttgt
    74041 taatttcttt agcaagaacg tgggtagccc aggcaccgtt atcacctgat tgaccattac
    74101 cccaaacgtc cacatagata aagtcgagac cgtcaccaag ttttttcttc aaatcttccc
    74161 aacgtgccaa acgaccatga gctaggtcat aggcagcatc aatgttgata ccttgatcta
    74221 gccagttcca accatagcta tagcttccat ctggattctt acggagaatt ttttcattga
    74281 agtatttaga ctcaggataa gtttctgaag cgttaacgtg gatacctaga tgagctccat
    74341 atttcttagc cttctcaatt agggtcttga agtcttcgac accaccgata cgcttaccaa
    74401 tatcagcata gttcaagtga ccagagtcat ggccttcgct accatatcct ttaaggaaaa
    74461 caccttgccc aagaccatct gtgtggagat tgattttctt gataccatcc aaggtcataa
    74521 ggaatggatt ttgtgcttga gaaccaaagt tcatcgcgat acggtaagct gtgatatcct
    74581 taactttttc ccaaccttga ggattgttca taatgctacg ataagcaatg gcaccatctt
    74641 gccaatcgac tttcttgtct gcattggcat cttcagtgat aacaacctta gcacttggaa
    74701 gttccttcgt gtattctggg aaaacaatgc ccttataagc tttttcccat tgccattcag
    74761 agctgtggat tcctacatag ttggcatttc cgactgtttc tttataagct gtcaaacgag
    74821 tccagtcatt cgaaccacca ccatagctat tttgagagtt actccaaaca ccagcagcaa
    74881 gcttatctgt agaaacaaat ccatacatgt aacccttggc taggtctttc attggattgg
    74941 ttacatcgat atgatcatct ccgctgacat gcgtattgtt tgacatggtt gccccatcaa
    75001 acttagcacc agtttgatca ctagaaacag agactaaagc attgccgagg aaactaatag
    75061 aagaaagtag ttttctttcg tcatcaatct tttgacctgg agtgacttga ttgtggttga
    75121 caatcttggt cacatcaaag tgcaattgat tgtccacaac ttgcaagcgt actgtcattt
    75181 ccgcattgat taagtgagca tcatcgcgaa gcttcatcaa gtactctgct gttgtctcat
    75241 tgattttctt ataagtgact tcaggggtga ttcggtggtt attgataaag acttggttga
    75301 actgttgcac ctgtcctggc aaagtatgtc cattcaagct gtattccttg acacgaggga
    75361 aggcttggtc aatcactgct ttgaggacct tagactggat cgtatcataa gtcaccttgc
    75421 tatcgtcaac aaccggacct gtttctttct gggcaggagt atcatccgct tttacgcctt
    75481 cttgattgtc tgttttaacg ctgacaactg tacggtcatt gccataagtt cctgccttga
    75541 gaaggatctt cttctcattt ttaagattat cattgaccgc cccaggcagt gtcactgtgt
    75601 caaagagatt gacatcgtta ttgctggcat tgagttgtcc atctgacttg agagtgatag
    75661 aaagacggtt tacagaaccc ggttctggtg caactacacg gttgccttta taccatgtgc
    75721 tattacctgg agttttgtat tcccagaacc agccatcctt gtcataaccg acaaaaacat
    75781 tattattggt atctttaaat ttcaggaaga caccaaagcg tgatttgccc ttttcagaat
    75841 cttctttgaa ggttaaatca acagttgcat ttccattggc atcaacggtc aagcccttct
    75901 tttcaaacag ggctggtttg cctgcgttat cattttgagc agttgagaat agttggttgt
    75961 agcggacacc tttttcttct cggatagtga ctgttccctg ttgttctttt ttctctaccg
    76021 tttgccattc aggagttacc gtcttaggtg tttcaggttt agcagctgca ggtttatcct
    76081 cttttggttt ttcttcagcc ggtttttctt tttcaagtgc taatagttct tcttctgtct
    76141 taggtccatc tgtaacttct ggagaacctt ggtcttctcc caccttaggc gcttcaaaat
    76201 cacgcccatc attctcgttt gctgttgcaa gagcagtagc taaatcagct ggtaagttcg
    76261 ccgtggaacc agactgcacg ctatctgcaa gaaccggact tgtcccaaag aatgcagctc
    76321 caatcataac agaagcaaca cctaatgaaa atttccgaat actatattta caacgttttt
    76381 caaataatcc tttattcata aacttctaaa tcctttcatt ttttagcaag cgtttacatt
    76441 tcctttttaa aaaatactcc ttcctctgaa agtgcaatgc ttaaccctga taaataaaaa
    76501 ataattgtac ttttaatata acaaataata gctgagaaag caataggaaa caagtaaaat
    76561 taacaaaaat tttctctatt ctgacaaaaa gaggctccaa cttttggggg tcagtacatt
    76621 tagaatcttt ctttacaaat gtaaaaaagg attcagcatt caagagaaat actaaatcct
    76681 ttcttatatt ttgcaacagt tatttcacat gttttgcgag atcttcttga gcctttttat
    76741 tagactcttc tttttctttc atccattttt cctgagcttt ttggtattca tctacagtga
    76801 ctgccttgtc ttgaagttcc aagtatttat acaagactgg ttcacttgta cctttatttc
    76861 ctgacaatgc aaatggtatt gtaaatggta ccatcttaga caagattggg cgccctgtac
    76921 gagatgtagt tggaataatc aaagcactat ctgtcaacca agcttgggct gcagcgtatt
    76981 tatcatagcg tttagcaaca tctgtagcct catcaccagc ctcagtgacc aatttttcgt
    77041 agtcatatag acctactttt ttagcagcta cattatcttc ccctgagtca aaccctaaat
    77101 atgttttagt actttctcct acagaaggtt tgataatatc aaggtaggtt gatggatcgg
    77161 caaagtctgg accccaaccg acattatctg ataaatccca gtcttcgcca gcagcatttt
    77221 cagcaaaata tgtaatattg tttacttcgt ctttttgtag ttgttggata tcaataatga
    77281 cattatcagc tcctaaagtt gcttccaagg attgtttcat agattggacg cgctgaactt
    77341 ttgtagttgc tgtctggtca actggcatat ccaaatgaat tgggaaagtc acaccttctg
    77401 cttgtaaggc tgatttagct ttagcaaatt cagccttggc tttttctgga ttgtaaagac
    77461 catcctgaga atctgcaaga ttaacatcct tccattcatc cccataagtg accaatttct
    77521 ctttgaccat atcgccaaag tttttaccat ctgcttgaac aaatgttggt ggaacaaaga
    77581 tattacgtaa gattttgctt gctccagttt gtccattcaa ctgagaggca taggctgtac
    77641 gatcaaaacc aaaggcaata gcctgacgga aatccttgtt taagagagcc tttttagtcg
    77701 atgccttttg ttcgtcgctg gtcttagatg tatatttata ggactgacgg tcaatatttg
    77761 taccaactag atacgtaata gagccttgtt gagtatagac aatattgtcc ttcatactct
    77821 tctcaagctc tgcgaaactt gcacttgttg gatagagacg agctgctgta aggctaccat
    77881 ctttaaagtt ttctgcaggt ttgctggtat cttgaccatc ccagaatgac aatttaactt
    77941 tgtcaacatg cacattgtcc ttatcccagt agttcggatt tttcgcaaat tcaacagagg
    78001 attttgtcac aatggatttc aacaaataag gaccgttata caagagacta cttggatccg
    78061 tcgctttggc aaaatcatcc ccttttgagt tcaaaaactc ttcattaact ggcgcaagca
    78121 cacccatggt tgtcttagaa ttccagaagc tttctggttt gttcaaagtg tactgaactg
    78181 tctgatcatc caaagcctta attcctactt gtgagaaatc tttgatttcc ccttttacat
    78241 aggcatccaa ccctttgatt gattcttgaa caaggtaaag agcatctgat tttttatcag
    78301 cagcatattt tagtcctgtt acaaagtctt gagctttgac tgccgcgtat tcttcacctt
    78361 cagaagtata ccattttgca tccttacgga tagtataagt gtaagtcaat ccatccttgg
    78421 atacagacca atcctcagcc atagacggca caaagttccc gtagcgatca ttttctagca
    78481 aaccatcaac cacgttactg gtaatatttg ctgtcgcagc cttagcagtt gtcaaatagt
    78541 tgaggttatc agggtctgtc tcataaatgt atgagaatgt cttctcacct ttagtgcttg
    78601 aacctgatcc agagcatgca gctaaagtag tcgccgccaa taatgtcacg cccgcaaggg
    78661 caagtagttt tgaacttttc atccttttct cctttaaaac tttctctcca ttatagactc
    78721 ttttcagaaa gttgtcaaca gaattttcag aatttttgaa aattattttt caaataacat
    78781 ctttgcaaaa aatatgaata tcgtaaccg
//
LOCUS       DAVBDR010000005        64158 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.005, whole genome shotgun sequence.
ACCESSION   DAVBDR010000005 DAVBDR010000000
VERSION     DAVBDR010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 64158)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 64158)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..64158
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.005"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            complement(134..481)
                     /locus_tag="VQ540_000334"
     CDS             complement(134..481)
                     /locus_tag="VQ540_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003017645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HET2544204.1"
                     /translation="MNLNQLDIIVSNVPQVCADLEHILDKKADYADDGFAQFTIGSHC
                     LMLSQNHLVPLENFQSGIIIHIEVEDVDQNYKRLNELGIKVLHGPTVTDWGTESLLVQ
                     GPAGLVLDFYRMK"
     gene            complement(592..2367)
                     /gene="spxB"
                     /locus_tag="VQ540_000335"
     CDS             complement(592..2367)
                     /gene="spxB"
                     /locus_tag="VQ540_000335"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000191798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HET2544205.1"
                     /translation="MTQGKITASAAMLNVLKTWGVDTIYGIPSGTLSSLMDALAEDKD
                     IRFLQVRHEETGALAAVMQAKFGGSIGVAVGSGGPGATHLINGVYDAAMDNTPFLAIL
                     GSRPVNELNMDAFQELNQNPMYNGIAVYNKRVAYAEQLPKVIDEACRAAISKKGPAVV
                     EIPVNFGFQEIDENSYYGSGSYERSFIAPALNEVEIDKAVEILNNAERPVIYAGFGGV
                     KAGEVITELSRKIKAPIITTGKNFEAFEWNYEGLTGSAYRVGWKPANEVVFEADTVLF
                     LGSNFPFAEVYEAFKNTEKFIQVDIDPYKLGKRHALDASILGDAGQAAKAILDKVNPV
                     ESTPWWRANVKNNQNWRDYMNKLEGKTEGELQLYQVYNAINKHADQDAIYSIDVGNTT
                     QTSTRHLHMTPKNMWRTSPLFATMGIALPGGIAAKKDNPDRQVWNIMGDGAFNMCYPD
                     VITNVQYDLPVINLVFSNAEYGFIKNKYEDTNKHLFGVDFTNADYAKIAEAQGAVGFT
                     VDRIEDIDAVVAEAVKLNKEGKTVVIDARITQHRPLPVEVLELDPKLHSEEAIKAFKE
                     KYEAEELVPFRLFLEEEGLQSRAIK"
     gene            complement(2574..4817)
                     /locus_tag="VQ540_000336"
     CDS             complement(2574..4817)
                     /locus_tag="VQ540_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HET2544206.1"
                     /translation="MTEIVKASLENGIQKIRIRAEKGYHPAHIQLQKGIPAEITFHRA
                     TPSNCYKEILFEEEGILEPIGVDEEKVIRFTPQELGRHEFSCGMKMQKGSYIVVEKTR
                     KSLSLLQRFWITSIFTVPLVILMIGMLTGSISHQVMHWGTFLATTPIMLVAGKPYIQS
                     AWASFKKHNANMDTLVALGTLVAYFYSLVALFAGLPVYFESAGFILFFVLLGAVFEEK
                     MRKNTSQAVEKLLDLQAKTAEVLSDDSYVQVPLEQVKVGDLIRVRPGEKIAVDGVVVE
                     GVSSIDESMVTGESLPVDKTVGDTVIGSTINHSGTLVFRAEKVGSETVLAQIVDFVKK
                     AQTSRAPIQDLTDKISGIFVPVVVILGIMTFWVWFVLLRDSVVVLGASFVSSLLYGVA
                     VLIIACPCALGLATPTALMVGTGRSAKMGVLLKNGTVLQEIQKVQTLVFDKTGTLTEG
                     KPVVTDIIGDEVEVFGLAASLEDASQHPLAEAIVKRASEAGLEFQTVENFQSLHGKGV
                     SGRINGKQVLLGNAKMLDGMDISNTYQDKLEELEKEAKTVVFLAVDNEIKGLLALQDI
                     PKENAKLAISQLKKRGLRTVMLTGDNAGVARAIADQIGIEEVIAGVLPEEKAHEIHKL
                     QQSGKVAFVGDGINDAPALSVADVGIAMGAGTDIAIESADLVLTTNNLLGVVRAFDMS
                     KKTFHRILLNLFWAFIYNVVGIPIAAGVFSGVGLALNPELAGLAMAFSSVSVLTSSLL
                     LNFSKID"
     gene            complement(4827..5198)
                     /locus_tag="VQ540_000337"
     CDS             complement(4827..5198)
                     /locus_tag="VQ540_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupredoxin domain-containing protein"
                     /protein_id="HET2544207.1"
                     /translation="MLNSIVTIICIALIAFILFWFFKKPEKSGQKAQQKNGYQEIRVE
                     VMGGYTPELIVLKKSVPARIVFDRKDPSPCLDQIVFPDFGVHANLPMGEEYVVEITPE
                     QVGEFGFACGMNMMHGKMIVE"
     gene            complement(5209..5604)
                     /locus_tag="VQ540_000338"
     CDS             complement(5209..5604)
                     /locus_tag="VQ540_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HET2544208.1"
                     /translation="MQISDAEWQVMKIIWMQGEQTSTDLIRVLAERFDWSKSTIQTLL
                     ARLVEKECLTRKKEGKSFVYSALLTLDQSRDLLVQDIKDKVCSRRIRNLLADLIVECE
                     FTQTDLEDLEAVISEKKSSAVTEVRCNCM"
     regulatory      5788..5886
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            5970..6761
                     /gene="thiD"
                     /locus_tag="VQ540_000339"
     CDS             5970..6761
                     /gene="thiD"
                     /locus_tag="VQ540_000339"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HET2544209.1"
                     /translation="MTYLPVALTIAGTDPSGGAGIMADLKSFQARDVYGMAVVTSLVA
                     QNTRGVQLIEHVSPQMLKAQLESVFSDIPPQAVKTGMLATTEIMEIIQPYLKKLDCPY
                     VLDPVMVATSGDALIDSSARDYLKTNLLPLATIITPNLPEAEEIVGFSIHDPEGMQRA
                     GRLILKEFGPQSVVIKGGHLKGGAKDFLFTKNEQFVWESPRIQTCHTHGTGCTFAAVI
                     TAELAKGKSLYQAVDKAKAFITKAIQDAPQLGHGSGPVNHTTFKD"
     gene            complement(6970..7602)
                     /locus_tag="VQ540_000340"
     CDS             complement(6970..7602)
                     /locus_tag="VQ540_000340"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HET2544210.1"
                     /translation="MNREALRLYLVTNRYQDSVESFLAKVETACRSGVTIVQLREKNL
                     TTNQYYQLAKQVKEITDAYQVPLIIDDRLDVCLAVDAAGLHIGDDELPVSVARKVLGP
                     EKILGVTAKTVKRALEAEKSGADYLGTGAIFPTTTKENAPITLISTLKTICQTVAIPV
                     VAIGGLTSENIDQLMGTGIAGVAVVRDLMQAEDIEAKTQAFLTKLHDILS"
     gene            complement(7595..8398)
                     /locus_tag="VQ540_000341"
     CDS             complement(7595..8398)
                     /locus_tag="VQ540_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HET2544211.1"
                     /translation="MQALTNPFPIGSSSLIHCMTNEISCEMLANGILALGCKPVMADD
                     PREVLDFTKQSQALFINLGHLSAEKEKAIRMAASYANQSSLPMVVDAVGVTTSSIRKS
                     LVKDLLDYRPTVLKGNMSEIRSLVGLKHHGVGVDASAKDQETEDLLQVLKDWCQTYPG
                     MSFLVTGPKDLIVSENQVAVLENGCTELDWITGTGDLVGALTAVFLSQGKTGFEASCL
                     AVSYLNIAAEKIVVQGMGLEEFRYQVLNQLSLLRRDENWLDTIKGEVYE"
     gene            complement(8398..8922)
                     /gene="thiW"
                     /locus_tag="VQ540_000342"
     CDS             complement(8398..8922)
                     /gene="thiW"
                     /locus_tag="VQ540_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001225563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy coupling factor transporter S component
                     ThiW"
                     /protein_id="HET2544212.1"
                     /translation="MRKHQLQVHKLTILSMMIALDVVLTPIFRIEGMAPMSSVVNILA
                     GIMMGPVYALAMATVTAFIRMTTQGIPPLALTGATFGALLAGLFYKYGRKFYFSALGE
                     IVGTGIIGSIVSYPVMVLFTGSAAKLSWFIYTPRFFGATLIGTAISFIAFRFLIKQEF
                     FKKVQGYFFAERID"
     gene            complement(8927..9619)
                     /gene="tenA"
                     /locus_tag="VQ540_000343"
     CDS             complement(8927..9619)
                     /gene="tenA"
                     /locus_tag="VQ540_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiaminase II"
                     /protein_id="HET2544213.1"
                     /translation="MEFTDIAMELSKKAWQASFHHPFILQLQEGNLEPAIFRYYLIQD
                     AYYLKAFSEIYHLLADKTSNQEMKRLLKQNAQGLVEGELFIRQQFFKELEINDQEMEQ
                     HPIAPTCYHYISHIYRQFAEPNLAIAFASLLPCPWLYHDIGKSLNLKPSPNPLYQQWI
                     ETYITDELEQQIREEGALVNQLYRESDETDKQKMLDAFHISVHMEAKFWEMAYQHQTW
                     KSDLQSLEKGEE"
     gene            complement(9630..10280)
                     /locus_tag="VQ540_000344"
     CDS             complement(9630..10280)
                     /locus_tag="VQ540_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt ABC transporter permease"
                     /protein_id="HET2544214.1"
                     /translation="MVKVATQTPIISLFLLILSLETSFIPSIALNLSVVAFCILFMLY
                     YRRFKMLAWMIILAIFPSFANYWAVQLHGDASQAVMLGTRAFVTVCIGLVFVSSISLK
                     ELLLYLAQKGLSRSWSYALIVVFNSFPLIQQEIKSLKEACLLRGQKLHFWSPLIYSKV
                     LMTVFRWRHLYLRALSAYGYDEHAQLKNSYRTFYIPKKTKLIYLLFFLLLQTSLFL"
     gene            complement(10282..11667)
                     /locus_tag="VQ540_000345"
     CDS             complement(10282..11667)
                     /locus_tag="VQ540_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2544215.1"
                     /translation="MGLELRAIQSPIFSEPFDFTFHAQAFTLLVGSSGSGKSSLFQMI
                     AQVSSLPYSGQVLIDGSEVSQLSIVERVQTVGILLQNPNHQFTMESLFEELVFTMENI
                     GYHLQEIDSKIAEVVQQCRCKDILHRLIHHLSGGEKQKAALAVLFAMNPRVYLLDEPF
                     ASIDRKSRIEILEILKELVYDGKTVILCDHDLSDYKAYIDHMVELRDGKLREVFQIPS
                     YEMTQVASKEVASSPELFHMNRVTGELGNRPLFSIADFTFYQGISCILGDNGVGKSTL
                     FRSILQFQKYKGSITWKGSVLKKKKSLYRDLTGVVQEAEKQFIRVSLREELQLDGPDS
                     ERNQRIFQALRYFDLEQAVDKSPYQLSGGQQKILQLLTILTSKASVILLDEPFAGLDD
                     RACHYFCKWIVEERNQGRSFLLISHRLDPLISVVDYWIEMTSQGLRHVKEVTITKPLT
                     SQSSNTQGEVR"
     gene            complement(11668..12228)
                     /locus_tag="VQ540_000346"
     CDS             complement(11668..12228)
                     /locus_tag="VQ540_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HET2544216.1"
                     /translation="MLKKWQLKDVILLAFLSIFFGGVFVGSGYVYNILSLLLTPLGLQ
                     AFANEILFGLWCMAAPIAAIFVPRVGSATIGEVLAALAEVLYGSQFGLGALLSGFVQG
                     LGSEFGFIVTKNRYESWLSLTANSIGITLVSFVYEYIKLGYYAFSLPFVLSLLVVRFI
                     SVYFFCTILVRAIVKLYHQFATGGKA"
     regulatory      complement(12490..12578)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(12787..13416)
                     /locus_tag="VQ540_000347"
     CDS             complement(12787..13416)
                     /locus_tag="VQ540_000347"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000468574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HET2544217.1"
                     /translation="MFHKELLKLYFICGTTTCQGKNLYTVVEEALKGGITLFQFREKG
                     EGALEGLEKLELAIQIKELCKKYNVPFIVNDDIDLAMEIDADGVHVGQDDIGVDEIRK
                     LMPDKIIGLSIRNEEEFQQSKVEYVDYVGVGPVFGTQSKDDAGGTIGYEGLELMRKLL
                     PQMPLVAIGGIQTKHIKDIIKTNMDGVSIISAISYAKNIEKTVREMSEQ"
     gene            complement(13418..14200)
                     /gene="thiM"
                     /locus_tag="VQ540_000348"
     CDS             complement(13418..14200)
                     /gene="thiM"
                     /locus_tag="VQ540_000348"
                     /EC_number="2.7.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HET2544218.1"
                     /translation="MTSLKLLKEKAPLVICITNDVVKNFTANGLVALGASPAMSEFPA
                     DLEDLLKYAGGLLINIGTLTDENWKLYQAALKIAEKYNVPAVLDPVACGAGEYRKKVA
                     DDLINNYKLAAIRGNAGEIASLVGIDVASKGVDSAGVDNIDEIALAANEKFNIPIVVT
                     GEVDAIAVNGEVVMIHNGSAMMPKVIGTGCLLGAVVASFIGLEKGQELKSLETAMLVY
                     NIAGEMAEKRPNGHLPGTFKVEFINALYEITDEDVKEFKRVK"
     gene            complement(14443..15111)
                     /locus_tag="VQ540_000349"
     CDS             complement(14443..15111)
                     /locus_tag="VQ540_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000449895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TenA family protein"
                     /protein_id="HET2544219.1"
                     /translation="METQDYAFQPGLTVGELLKSSQKDWQAAINHRFVKELFAGTIEN
                     KVLKDYLIQDYHFFDAFLSMLGACVAHADKLESKLRFAKQLGFLEADEDGYFQKAFKE
                     LKVAENDYLEVTLHPVTKAFQDLMYSAVASSDYAHLLVMLVIAEGLYLDWGSKDLALP
                     EVYIHSEWINLHRGPFFAEWVQFLVDELNRVDKNREDLTELQQRWNQAVALELAFFDI
                     GYDV"
     regulatory      complement(15326..15414)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(15668..16804)
                     /gene="lctO"
                     /locus_tag="VQ540_000350"
     CDS             complement(15668..16804)
                     /gene="lctO"
                     /locus_tag="VQ540_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate oxidase"
                     /protein_id="HET2544220.1"
                     /translation="MSYKTSNAEGHVDFINTYDLEPMAQQVIPKAAFGYIASGAEDTF
                     TLRENIRAFNHKLIVPHTLCDVENPSTEIEFAGEKLSSPIIMAPVAAHKLANEQGEVA
                     TARGVHEFGSLYTTSSYSTVDLPEISEALQGTPHWFQFYFSKDDGINRHIMDRVKAEG
                     YKAIVLTADATVGGNREVDKRNGFVFPVGMPIVEEYLPEGAGKSMDFVYKSAKQRLSP
                     RDVEFIAEYSGLPVYVKGPQCREDVERSLAAGASGIWVTNHGGRQIDGGPAAFDSLQE
                     VAEAVDRRVPIVFDSGVRRGQHVFKALASGADLVAIGRPVIYGLALGGSVGVRQVFEH
                     LNAELKTVMQLSGAQTIEDVKHFKLRHNPYNPTFPVDPRDLKLY"
     gene            complement(17429..18919)
                     /gene="lysS"
                     /locus_tag="VQ540_000351"
     CDS             complement(17429..18919)
                     /gene="lysS"
                     /locus_tag="VQ540_000351"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003055423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HET2544221.1"
                     /translation="MSTEHMEELNDQQIVRREKMAALREQGIDPFGKRFERTANSQEL
                     KDKYANLDKEQLHDKNETATIAGRLITKRGKGKVGFAHLQDREGQIQIYVRKDAVGEE
                     NYEIFKKADLGDFLGVEGEVMRTDMGELSIKATHITHLSKALRPLPEKFHGLTDVETI
                     YRKRYLDLISNRESFERFVTRSKIISEIRRYLDQKGFLEVETPVLHNEAGGAAARPFI
                     THHNAQNIDMVLRIATELHLKRLIVGGMERVYEIGRIFRNEGMDATHNPEFTSIEVYQ
                     AYADFQDIMDLTEGIIQHAAKSVKGDGPVNYQGTEIKINEPFKRVHMVDAIREITGVD
                     FWQDMTLEEAKTIAAEKKVPVEKHYTEVGHIINAFFEEFVEETLIQPTFVYGHPVAVS
                     PLAKKNPEDQRFTDRFELFIMTKEYGNAFTELNDPIDQLSRFEAQAKAKELGDDEATG
                     IDYDYIEALEYGMPPTGGLGIGIDRLCMLLTDTTTIRDVLLFPTMK"
     gene            complement(19047..19193)
                     /locus_tag="VQ540_000352"
     CDS             complement(19047..19193)
                     /locus_tag="VQ540_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate oxidase"
                     /protein_id="HET2544222.1"
                     /translation="MSYKTSNAEGHVDFINTYDLEPMAQQVIPKAAFGYIASGAGDTF
                     TSFQ"
     gene            19419..20087
                     /locus_tag="VQ540_000353"
     CDS             19419..20087
                     /locus_tag="VQ540_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006531263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET2544223.1"
                     /translation="MVEQYLPLYQKAFFLTLHIAVWGILGSFLLGLIVSIIRHYRILV
                     LAQVATAYIELSRNTPLLIQLFFLYFGLPRIGIVLSSEVCATLGLVFLGGSYMAESFR
                     SGLEAISQTQQEIGLAIGLTPLQVFYYVVLPQATAVALPSFSANVIFLIKETSVFSAV
                     ALADLMYVAKDLIGLYYETDIALAMLVVAYLIMLLPISLVFSWIERRLRHAGFGNPST
                     LSRK"
     gene            20047..20724
                     /locus_tag="VQ540_000354"
     CDS             20047..20724
                     /locus_tag="VQ540_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001154125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET2544224.1"
                     /translation="MQDSGIQVLFQGNNLLRILQGLGVTIEISILSVLLSMMFGTVMG
                     IIMTSHSRIIRFLTRLYLDFTRIMPQLVLLFIVYFGLARNFNINISGETSAIIVFTLW
                     GAAEMGDLVRGAITSLPKHQFESGQALGLTNVQLYYHIIIPQVLRRLLPQAINLVTRM
                     IKTTSLVVLIGVVEVTKVGQQIIDSNRLTIPTASFWIYGTILVLYFAVCYPISKLSTH
                     LEKHWRN"
     gene            20725..21482
                     /locus_tag="VQ540_000355"
                     /pseudo
     CDS             20725..21482
                     /locus_tag="VQ540_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000401.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
     gene            21494..22355
                     /locus_tag="VQ540_000356"
                     /pseudo
     CDS             21494..22355
                     /locus_tag="VQ540_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765255.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine ABC transporter substrate-binding
                     protein"
     gene            complement(22435..23082)
                     /locus_tag="VQ540_000357"
     CDS             complement(22435..23082)
                     /locus_tag="VQ540_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2544225.1"
                     /translation="MNEIIILKNIELKLKKTCVFQNLNFSCKQGEIIGITGANGSGKS
                     VLFKLIAGLYSPSYGEVLINGENIVPERKIPANLGALIEEPGFINYYSGFKNLQYLAS
                     IRGVVGNQEINDTLKIVGLYEQKDQKVKTYSLGMRKKLGIAQAIMENPSILLLDEPMN
                     ALDKSSVENMRTLFRKLSSEKGTTILIASHSEEDIRILCDKVYAIEDKVCTLCSD"
     gene            complement(23079..23777)
                     /locus_tag="VQ540_000358"
     CDS             complement(23079..23777)
                     /locus_tag="VQ540_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2544226.1"
                     /translation="MGKLSSHMWRLNKIIYTKYFWGYVLFWILICLGLWYWLEGNDRL
                     VIEILKGPNLSQNSFLVLSIWLLHWFIIHTFFLAVVYRRRASDFFMEVIRFSSIKLWI
                     RYQIWTCFLYGLILIMVKVLVIQFMLQLPNWDIGVLFIVDSLNACVLVLFCFMLYALG
                     ANVQMNFACVSFFLLMIVFGGLFVGNRTNYLFYILNRGNGDVGGDLFLQLLFLVFLFQ
                     SIFYFTRQKRRFIE"
     gene            complement(23787..24539)
                     /locus_tag="VQ540_000359"
     CDS             complement(23787..24539)
                     /locus_tag="VQ540_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2544227.1"
                     /translation="MKQFVQFYKKDFLSVLVYFILLLSCVLSSTVYLLRCRQYSIHPN
                     VLEWILVLLQDMTTGVYCFPFTYILFFFYLMNNYFNRLECRIRLKSIKHFTSFSFKLA
                     ALSTGIWTATLFLLIFLIAFSNGFSFSLEIKEVDFLREFYGISIANNASFFIGFFFSY
                     IAYYFFLSLLTISSFSWFKKSNMSLVFLFTFLFVESLFWIYQLNNGIIGLLPIFQYMV
                     NSNPYALIYWLTLLSIIIPLTVFSVHRNWRRV"
     gene            complement(24539..25303)
                     /locus_tag="VQ540_000360"
     CDS             complement(24539..25303)
                     /locus_tag="VQ540_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2544228.1"
                     /translation="MEFFICNLVRVVQSPRFYMSLFLTLLCMSLGNFLAFNGIYKIEG
                     LSIFFAASSIRGFSPISLVAALICTLPYSSQIIEDAESHFLTAQLCRISKKKYLAIVG
                     STAIISSFLVFFLPYLLLLGINLLVTPYQEIYIGDYSGALKELFDSNQLLYSLVTTLW
                     YGVWGAVFSIFGLASALLVKKKIGAIFIPVAYMMVGGIFWAILGLSYLEPVTTLALGY
                     QKDISLSLVSGHLAFILFVSCLVVYGTFFLHSEDYV"
     gene            complement(25399..25802)
                     /locus_tag="VQ540_000361"
                     /pseudo
     CDS             complement(25399..25802)
                     /locus_tag="VQ540_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000829085.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(25982..26614)
                     /locus_tag="VQ540_000362"
     CDS             complement(25982..26614)
                     /locus_tag="VQ540_000362"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HET2544229.1"
                     /translation="MTLAKDIASHLLKIQAVYLKPEEPFTWASGIKSPIYTDNRVTLA
                     YPETRTLIENGFVEAIKEAFPEVEVIAGTATAGIPHGAIIADKMDLPFAYIRSKPKDH
                     GAGNQIEGRVAQGQKMVVVEDLISTGGSVLEAVAAAKREGADVLGVVAIFSYQLPKAD
                     KNFADAGVKLVTLSNYRELIHLAQEEGYITPEGLDLLKRFKEDQENWQEG"
     gene            complement(26648..27349)
                     /gene="pyrF"
                     /locus_tag="VQ540_000363"
     CDS             complement(26648..27349)
                     /gene="pyrF"
                     /locus_tag="VQ540_000363"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HET2544230.1"
                     /translation="MREHRPIIALDFPSFEAVKEFLALFPAEESLYLKVGMELYYAAG
                     PEIVSYLKGLGHSVFLDLKLHDIPNTVKSAMKVLSQLGVDMTNVHAAGGVEMMKAARE
                     GLGSQAKLIAVTQLTSTSEAQMQEFQNIQTSLQESVIHYAKKTAEAGLDGVVCSAQEV
                     QVIKQATNPDFICLTPGIRPAGVAVGDQKRVMTPADAYQIGSDYIVVGRPITQAEDPV
                     AAYHAIKDEWTQNWN"
     gene            27670..27762
                     /locus_tag="VQ540_000364"
                     /pseudo
     CDS             27670..27762
                     /locus_tag="VQ540_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011516271.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(28084..28797)
                     /locus_tag="VQ540_000365"
     CDS             complement(28084..28797)
                     /locus_tag="VQ540_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2544231.1"
                     /translation="MLKRFLALVWLRCQIILSNKSILLQVLVPFAFTYFYKYLMETQG
                     KVNDQQALVLLMMCLPFSLALAVGSPITIILSEEKEKYNLQTLLLSGVKGSEYILSTM
                     FLPFLLTFVIMGTTPLILGVTIVHTFNYITIVLLTSLSIILFYLLIGLTAKSQVVAQV
                     ISLPAMILVAFLPMLSGLDKTVAKITDYSFMGLFTKFFTKWEGFSWNKTLIPNLTLLI
                     WIVLLLTLITITIRKKKIS"
     gene            complement(28790..29485)
                     /locus_tag="VQ540_000366"
     CDS             complement(28790..29485)
                     /locus_tag="VQ540_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2544232.1"
                     /translation="MTGQFLADKGQSIILGQKSQNLTSGELKRIGLVSDTSGFYEKMS
                     LYNNLLFYSKFYNISKSRVDNLLKRVGLYDSRKMVAGKLSTGMRQRMLLARALINKPA
                     VLFLDEPTSGLDPTTSRTIHELILELKTAGTTIFLTTHDMNEATLLCDYVALLNKGKL
                     VEQGAPSELIQRYNKDKKIKVTDYNGNQITFDFTSLEQVSQADLENIFSIHSCEPTLE
                     DIFITLTGGKLNA"
     gene            complement(29825..31157)
                     /locus_tag="VQ540_000367"
                     /pseudo
     CDS             complement(29825..31157)
                     /locus_tag="VQ540_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812020.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ThiF family adenylyltransferase"
     gene            complement(31141..31939)
                     /locus_tag="VQ540_000368"
                     /pseudo
     CDS             complement(31141..31939)
                     /locus_tag="VQ540_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001824573.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M50 family protein"
     gene            complement(32729..33928)
                     /gene="divIB"
                     /locus_tag="VQ540_000369"
     CDS             complement(32729..33928)
                     /gene="divIB"
                     /locus_tag="VQ540_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIB"
                     /protein_id="HET2544233.1"
                     /translation="MSKDKKNEDKEILEELKELSEWQKRNQEYLKKKAEEEAALAEEK
                     EKERQARMGEESEKSEDKQDQESETDQEDSESAKEESEEKVASSEADKEKEEKEEPES
                     KEKEEQDKKLSKKATKEKPAKAKIPGIHILRAFTILFPSLLLLIVSAYLLSPYATMKD
                     IRVEGTVQTTADDIRQASGIQDSDYTINLLLDKAKYEKQIKSNYWVESAQLVYQFPTK
                     FTIKVKEYDIVAYYISGENHYPILSSGQLETSSVSLNSLPETYLSVLFNDSEQIKVFV
                     SELAQISPELKAAIQKVELAPSKVTSDLIRLTMNDSDEVLVPLSEMSKKLPYYSKIKP
                     QLSEPSVVDMEAGIYSYTVADKLIMEAEEKAKQEAKEAEKKQEEEQKKQEEESNRNQT
                     TQRSSRR"
     gene            complement(33938..34996)
                     /locus_tag="VQ540_000370"
     CDS             complement(33938..34996)
                     /locus_tag="VQ540_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine--N-acetylmuramyl-
                     (pentapeptide) pyrophosphoryl-undecaprenol
                     N-acetylglucosamine transferase"
                     /protein_id="HET2544234.1"
                     /translation="MKKIVFTGGGTVGHVTLNLLLMPKFIEDGWEVHYIGDKRGIEHQ
                     EILKSGLDVTFHSIATGKLRRYFSWQNMLDVFKVCWGIVQSLFIMLRLRPQTLFSKGG
                     FVSVPPVIAARVSGVPVFIHESDLSMGLANKIAYKFATKMYSTFEQASSLSKVEHVGA
                     VAKVSDQKNPEPDELVDIQSHFNHKLPTVLFVGGSAGARVFNQLVTDHKKELTERYNI
                     INLTGDSSLNELSQNLFRVDYVTDLYQPLMELADIVVTRGGANTIFELLAIAKLHVIV
                     PLGREASRGDQLENAAYFVKKGYAEDLQESDLTLDSLEEKLSHLLSHKEDYQAKMKAS
                     KELKSLADFYQLLKKDLS"
     gene            complement(34998..36350)
                     /locus_tag="VQ540_000371"
     CDS             complement(34998..36350)
                     /locus_tag="VQ540_000371"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HET2544235.1"
                     /translation="MKVIDQFKNKKVLVLGLAKSGESAARLLDKLGAIVTVNDGKPFE
                     DNPAAQSLLEEGIKVITGGHPLELLDEEFALMVKNPGIPYNNPMIEKALAKGIPVLTE
                     VELAYLISEAPIIGITGSNGKTTTTTMIGEVLTAAGQHGLLSGNIGYPASQVAQIASD
                     KDTLVMELSSFQLMGVQEFHPEIAVITNLMPTHIDYHGSFSEYVAAKWNIQNKMTAAD
                     FLVLNFNQDLAKDLTSKTEATVVPFSTLEKVDGAYLEDGQLYFRGEVVMAANEIGVPG
                     SHNVENALATIAVAKLRGVDNQTIKETLSAFGGVKHRLQFVDDIKGVKFYNDSKSTNI
                     LATQKALSGFDNSKVVLIAGGLDRGNEFDELVPDITGLKKMVILGQSAERVKRAADKA
                     GVAYVEATDIADATRKAYELATQGDVVLLSPANASWDMYANFEVRGDLFIDTVAELKE
                     "
     gene            complement(36454..37095)
                     /locus_tag="VQ540_000372"
     CDS             complement(36454..37095)
                     /locus_tag="VQ540_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2544236.1"
                     /translation="MIELKNISKKFGSRQLFSDTNLHFEGGKIYALIGTSGCGKTTFL
                     NMIGRLEPYDKGQIIYDGTSLKDIKPSVFFRDYLGYLFQDFGLIESQTVKENLNLGLV
                     GKKLKEKEKISLMKQALNCVNLSYLDLKQPIFELSGGEAQRVALAKIILKDPPLILAD
                     EPTTSLDPKNSEELLSILESLKNPNRTIIIATHNPLIWEQVDQVIRVTDLSHR"
     gene            complement(37097..39118)
                     /locus_tag="VQ540_000373"
     CDS             complement(37097..39118)
                     /locus_tag="VQ540_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000732428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HET2544237.1"
                     /translation="MKKLFILLSTFFLSFFLAWIIVLRAPQYLYASYDSVSLLRVKKD
                     TQEPTREVFEQELENFANSEQSLIARRIVEPSKDGTTHFTYATYGQGTLPKEFQEASQ
                     ESRERSDPLNSYLLLSGSLTKEKLADKLGDLGYKASADRKIPPYFLAFRILLNPLILI
                     SLAIFGLSFFALVIITRIKEMRAAGIKLFSGQTLLSIMGHSLSTDIKWLLLSALLSFL
                     GGGVVLFSQGLFYPILLATYGFGISFYLLFLLAISILLMLLYLMSLSYKALVPVIKGR
                     LPLKRLMILTLLCQLVAVFTVGYAVKTGLMSYQRLKELEISKQAWQDRADYYQISFGL
                     GDRGKDTENQSKWYAFAKEAIEEEQALYVKDNLLHFANPQGKNEQGETLDTYSPDANT
                     LYVSPSYLDKEKVVVDAETKQKLAHLQKGEFILLLPEHLRSREAELKKVFEERLSYYG
                     KSGEEASAPLDYEMKAHVSYLSMGEKRFVYNNGENPVSTQYLTDPILVVFTPTSTGDS
                     FISLSSWSINAGKQLFIKGYESGLELLKKAGIYEQVSYLKEGRSVYLTRYNEVQTETA
                     TLILGAIVGIASSLLLFYSVNLLYFEQFRRDILIKRISGLRFFETHAQYMVSQFASFV
                     FGASLFILSSRDLVIGLLTLLVFLASAVLTLYRQAQKESRVSMTIMKGK"
     gene            complement(39189..39488)
                     /locus_tag="VQ540_000374"
     CDS             complement(39189..39488)
                     /locus_tag="VQ540_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HET2544238.1"
                     /translation="MKTKKHRLLALALISSFTLLGAASAAVQYPDGGVWTYGEGSGGG
                     WAFSNYYHGKKYHYSSLVSRWNSHSDKGEASAGKTSYAWIWTKWGEQVAFYCDYD"
     gene            complement(39854..40108)
                     /locus_tag="VQ540_000375"
     CDS             complement(39854..40108)
                     /locus_tag="VQ540_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3165 family protein"
                     /protein_id="HET2544239.1"
                     /translation="MVYLVLGILLLLLYVFATPESIKGTVNIVAMVCILVALLILLVL
                     SFLKIFQLPTEIFLAIAMLILAYFSVRDITLMPVKKSKRR"
     gene            complement(40128..41969)
                     /gene="typA"
                     /locus_tag="VQ540_000376"
     CDS             complement(40128..41969)
                     /gene="typA"
                     /locus_tag="VQ540_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003078415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HET2544240.1"
                     /translation="MTKLREDIRNIAIIAHVDHGKTTLVDELLKQSETLDARTELAER
                     AMDSNDIEKERGITILAKNTAVAYNGTRINIMDTPGHADFGGEVERIMKMVDGVVLVV
                     DAYEGTMPQTRFVLKKALEQDLVPIVVVNKIDKPSARPAEVVDEVLELFIELGADDDQ
                     LDFPVVYASAINGTSSLSDDPADQEATMAPIFDTIIDHIPAPVDNSDEPLQFQVSLLD
                     YNDFVGRIGIGRVFRGTVKVGDQVTLSKLDGTTKNFRVTKLFGFFGLERREIQEAKAG
                     DLIAVSGMEDIFVGETITPTDAVEALPILHIDEPTLQMTFLVNNSPFAGKEGKWVTSR
                     KVEERLQAELQTDVSLRVDPTDSPDKWTVSGRGELHLSILIETMRREGYELQVSRPEV
                     IVKEIDGVKCEPFERVQIDTPEEYQGSVIQSLSERKGEMLDMISTGNGQTRLVFLVPA
                     RGLIGYSTEFLSMTRGYGIMNHTFDQYLPLIPGEIGGRHRGALVSIDAGKATTYSIMS
                     IEERGTIFVNPGTEVYEGMIIGENSRENDLTVNITKAKQMTNVRSATKDQTAVIKTPR
                     ILTLEESLEFLNDDEYMEVTPESIRLRKQILNKAEREKANKKKKSAE"
     gene            42131..42856
                     /locus_tag="VQ540_000377"
     CDS             42131..42856
                     /locus_tag="VQ540_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA pseudouridine(516) synthase"
                     /protein_id="HET2544241.1"
                     /translation="MRLDNLLAQEKVSRKAMKQALLRGEILVDGCPARSLAQNIDTGL
                     QELLFQDRIIQGYEHTYLMLHKPAGVVTANKDKELPTVMDLLPSDIQSDKLYAVGRLD
                     RDTTGLLLLTDNGPLGFQLLHPQYHVDKTYQVQVNELLTPDHIQAFQKGIVFLDGTVC
                     KPAKLEILSASPSLSQASITISEGKFHQIKKMFLSVGVKVTSLKRIQFGDFTLNPDLA
                     ESNYRPLNQKELQIIKNYLEMSR"
     gene            complement(42896..43123)
                     /locus_tag="VQ540_000378"
     CDS             complement(42896..43123)
                     /locus_tag="VQ540_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2544242.1"
                     /translation="MKEKKKNPLFVGILSIILGLLFPIVGLILGIIGLVLAISYQKES
                     QLDYKIEKILNILGIVISVVNWIVAIALIFR"
     gene            complement(43212..43592)
                     /locus_tag="VQ540_000379"
     CDS             complement(43212..43592)
                     /locus_tag="VQ540_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HET2544243.1"
                     /translation="MVTWILWALILAMLAWMGFNYLRIRRAAKIVDNEEFEALIRTGQ
                     LIDLRDPAEFHRKHILGARNIPSSQLKTSLAALRKDKPVLLYENQRAQRVTNAALYLK
                     KQGFSEIYILSYGLDSWKGKVKTS"
     gene            complement(43592..43861)
                     /locus_tag="VQ540_000380"
     CDS             complement(43592..43861)
                     /locus_tag="VQ540_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HET2544244.1"
                     /translation="MSLFLKKTQNFARMSLMKTFYDVQQFLKRFGIIVYMGKRLYDIE
                     LMKLELSRIYDAGLMDKLDYLEAEAVLRREHKVELDYIEKNGEKN"
     gene            43925..44833
                     /locus_tag="VQ540_000381"
     CDS             43925..44833
                     /locus_tag="VQ540_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HET2544245.1"
                     /translation="MRIQQLHYIIKIVETGSMNEAAKQLFITQPSLSNAVRDLENEMG
                     IEIFIRNPKGITLTRDGMEFLSYARQVVEQTQLLEERYKNPVAHRELFSVSSQHYAFV
                     VNAFVSLLKKSDMEKYELFLRETRTWEIIDDVKNFRSEVGVLFLNSYNRDVLTKMLDD
                     NHLLAHHLFTAQPHIFVSKTNPLAKKDKVKLSDLENFPYLSYDQGTHNSFYFSEEILS
                     QEHHKKSIVVSDRATLFNLLIGLDGYTIATGILNSNLNGDNIVSIPLDIDDPIELVYI
                     QHEKTSLSKMGERFIDYLLEEVQFDS"
     gene            complement(44887..45642)
                     /locus_tag="VQ540_000382"
     CDS             complement(44887..45642)
                     /locus_tag="VQ540_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HET2544246.1"
                     /translation="MPTILITGASGGLAQEMVKLLPNDQLILLGRNKEKLAQLYGNYS
                     HAELIEIDITDDSALEALVTDLYLRYGKIDVLINNAGYGIFEGFDQIADKDIHQMFEV
                     NTFALMNLSRHLAARMKESSKGHIINIVSMAGLIATGKSSLYSATKFAAIGFSNALRL
                     ELMPYGVYVTTVNPGPIRTGFFDQADPDGTYLKSVDRFLLEADAVAKKIVKIIGKNKR
                     ELNLPILLNLAHKFYTLFPKLADKLAGETFNYK"
     gene            complement(45663..46592)
                     /locus_tag="VQ540_000383"
     CDS             complement(45663..46592)
                     /locus_tag="VQ540_000383"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000354350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HET2544247.1"
                     /translation="MDIQFLGTGAGQPSKARNVSSLALKLLDEINEVWLFDCGEGTQN
                     RILETTIRPRKVSKIFITHLHGDHIFGLPGFLSSRAFQANEEQTDLEIYGPQGIKSFV
                     LTSLRVSGSRLPYRIHFHEFDQDSLGKILETDKFTVYAEELDHTIFCVGYRVMQKDLE
                     GTLDAEKLKAAGVPFGPLFGKIKNGQDLVLEDGTEIKAADYISAPRPGKIITILGDTR
                     KTDASVRLAVNADVLVHESTYGKGDEKIARNHGHSTNMQAAQVAVEAGAKRLLLNHIS
                     ARFLSKDISKLKKDAATIFENVHVVKDLEEVEI"
     gene            complement(46607..47230)
                     /locus_tag="VQ540_000384"
     CDS             complement(46607..47230)
                     /locus_tag="VQ540_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine beta-lyase"
                     /protein_id="HET2544248.1"
                     /translation="MTDIKTLALKYGGYTSLDKVYLDQLLAGKTEQEQLTLITPPPSV
                     VNAYFAELYQKKSPQAATDYFAELSQELNLYNTEPSFTLENKPFIRLNLSGKSFGFCY
                     ESDGFGRIFSENEEKISDDLLFEIAQIFSHQLVFEESGKIYMKPVKDEEVVSLESLTA
                     LTDLERLADGRKRLKGYSQEDLLQEAAAFSGKRYFRSENRTAMLYID"
     gene            complement(47223..48461)
                     /gene="hflX"
                     /locus_tag="VQ540_000385"
     CDS             complement(47223..48461)
                     /gene="hflX"
                     /locus_tag="VQ540_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000573186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HET2544249.1"
                     /translation="MIETEKKEERVLLIGVELQGMDSFDLSMEELASLAKTAGAVVVD
                     SYRQKREKYDSKTFVGSGKLEEIALMVDAEEITTVIVNNRLTPRQNVNLEEVLGVKVI
                     DRMQLILDIFAMRARSHEGKLQVHLAQLKYLLPRLVGQGIMLSRQAGGIGSRGPGESQ
                     LELNRRSVRNQITDIERQLKVVEKNRATVREKRLESSTFKIGLIGYTNAGKSTIMNIL
                     TSKTQYEADELFATLDATTKSIHLGGNLQVTLTDTVGFIQDLPTELVSSFKSTLEESK
                     HVDLLVHVIDASNPYHEEHEKTVLSIMKDLDMEDIPHLTLYNKADLVEDFTPTQTPYT
                     LISAKSEDSRENLQALLLDKIKEIFEAFTLRVPFSKSYKIHDLESVAILEERDYQEDG
                     EVITGYISEKNKWRLEEFYD"
     gene            complement(48454..49338)
                     /gene="miaA"
                     /locus_tag="VQ540_000386"
     CDS             complement(48454..49338)
                     /gene="miaA"
                     /locus_tag="VQ540_000386"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HET2544250.1"
                     /translation="MKTKIIVIVGPTAVGKTALAIEVAKCFNGEVVSGDSQQVYRGLD
                     IGTAKASPEEQAAVPHHLIDVREITESYSAFDFVSEAKMTIEDIHSRGKLAIIAGGTG
                     LYIQSLLEGYHLGGETPHEEILAYRASLEPYSDEELAHLVEQAGLEIPQFNRRRAMRA
                     LEIAHFGQDLENQEILYEPLIICLDDERSQLYERINHRVDLMFEAGLLDEAKWLFDHS
                     PNVQAAKGIGYKELFPYFRGEQTLEEARESLKQATRRFAKRQLTWFRNRMQVTFYQIG
                     ESGVQDRILSQIEEFLDD"
     gene            49459..49629
                     /locus_tag="VQ540_000387"
     CDS             49459..49629
                     /locus_tag="VQ540_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001051775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HET2544251.1"
                     /translation="MAKGFAKGLVTGVAGTVAAVAGAVYAFKKKVIEPEEQKAAFIEE
                     NRKKAARRRVSR"
     gene            complement(49677..50516)
                     /locus_tag="VQ540_000388"
     CDS             complement(49677..50516)
                     /locus_tag="VQ540_000388"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003011065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HET2544252.1"
                     /translation="MTKADTIFKENIERILKEGVFSEQARPKYKDGTVANSKYVTGAF
                     SEYDLSKGEFPIITLRPIAIKSAIKEVLWIYQDQSNSLEVLNDKYNVHYWNDWEVGDT
                     GTIGERYGAVVKKHDIINKLLKQLETNPWNRRNIISLWDYQAFEETDGLLPCAFQTMF
                     DVRRVDGEIYLDATLTQRSNDMLVAHHINAMQYVALQMMIAKHFGWKVGKFFYFINNL
                     HIYDNQFEQAQELLRREPSNCQPRLVLNVPDGTNFFDIKAEDFELVDYDPVKPQLKFD
                     LAI"
     gene            complement(50613..51572)
                     /locus_tag="VQ540_000389"
     CDS             complement(50613..51572)
                     /locus_tag="VQ540_000389"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002919069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HET2544253.1"
                     /translation="MSQKIIGIDLGGTSIKFAILTTAGEIQGKWSIKTNILDEGSHIV
                     DDMIESIQHRLDLLGLAAADFQGIGMGSPGVVDRDKGTVIGAYNLNWKTLQPIKQKIE
                     KALGIPFFIDNDANVAALGERWMGAGDNQPDVVFMTLGTGVGGGIVAEGKLLHGVAGA
                     AGELGHITVDFDQPISCTCGKKGCLETVASATGIVNLTRRYADEYEGDAALKRLIDNG
                     EEVTAKTVFDLAKEGDDLALIVYRNFSRYLGIACANIGSILNPSTIVIGGGVSAAGEF
                     LLQGVQKVYDENTFPQVRTSTKLALATLGNDAGVIGAASLVLQ"
     gene            complement(51699..52697)
                     /locus_tag="VQ540_000390"
     CDS             complement(51699..52697)
                     /locus_tag="VQ540_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HET2544254.1"
                     /translation="MNKRLFLKMSLVTLPILALFSQPVLAEENIHFSSCKEAWANGYS
                     DLHEGEPGYSAKLDRDHDGVACELKNAPKGAFKAKQAATTQTDTTSSTASGWVKQDGS
                     WYYFDGNGNLVKNAWQGNYYLKADGKMAQSEWIYDSSYQAWYYLKSDGSYAKNAWQGA
                     YYLKSNGKMAQGEWVYDSSYQAWYYLKSDGSYARNAWQGNYYLKSDGKMAKGEWVYDA
                     TYQAWYYLTSDGSYAYSTWQGNYYLKSDGKMAVNEWVDGGRYYVGADGVWKEGQASTA
                     SSSNDSNSEYSAALGKAKSYNSLFHMSKKRMYRQLTSDFDKFSNDAAQYAIDHLDG"
     gene            complement(52747..53364)
                     /locus_tag="VQ540_000391"
     CDS             complement(52747..53364)
                     /locus_tag="VQ540_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000766583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HET2544255.1"
                     /translation="MKLIFLHGLGQSAESWKEVRNLLTDYPSEAIELFPSGVSNYQQA
                     KERVYQHLAQETEPFVLIGLSLGAALTLELSSYDLPNLRALILSGCPLKLAGNILFYL
                     QLLIFKLLPKRVFEKQGADKTLMVGVSEELKTLDLTDIAGTCSYPTLLICGSKDKPNL
                     SSMKALHRLLTDSQFQIIPDGPHVLNKAKPKEFVEKTRSFLELLK"
     gene            complement(53365..55086)
                     /gene="pabB"
                     /locus_tag="VQ540_000392"
     CDS             complement(53365..55086)
                     /gene="pabB"
                     /locus_tag="VQ540_000392"
                     /EC_number="2.6.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component I"
                     /protein_id="HET2544256.1"
                     /translation="MHRKTVIDFRTLGERYTFAQPIKELKTRNVEEVADLLAQVESYQ
                     EQGYYVVGYVSYEAAPAFEEKLAVHKDPLLGEYLLYFTVHDSVETSPIPLTYEDIDLP
                     SNWQEVTSAADYEKAIAQIHHHLRQGDTYQVNYTVQLKQKLSANPFAIYNRMVVEQEA
                     GYNAYVEHDEMAVISMSPELFFEQNDRELTTRPMKGTTQRGVTDQEDLEQASWLEQDP
                     KNRSENMMIVDLLRNDMNRISEVGSEHVERLCQVEQYSTVWQMTSTIKSQLREDVDLV
                     EIFRSLFPCGSITGAPKIATMEIIKDLEPQPRGVYCGTIGLLLPNGRRIFNVAIRTIQ
                     LHKGQAIYGVGGGITWDSTWESEYREVHQKAAVLYRKQARFQLITTGEISQKNLLFED
                     QHLERLRKASRYFAFPFDAEDLGHKIEEECQDCEANRDYRLRISLSKSGEIEVNRQVL
                     TPLSTSFCQAQVCLQEAALNQSFTYFKTTHRPHLSLGEQEKIYHNKSGELLETSIGNL
                     VLKIAGKLYTPPIRLGILPGIYRQYLLETGQVEEKVLTLADLTQAEAIYGCNAVRGLY
                     ELSLEEN"
     gene            complement(55155..60842)
                     /locus_tag="VQ540_000393"
     CDS             complement(55155..60842)
                     /locus_tag="VQ540_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HET2544257.1"
                     /translation="MFKKDRFSIRKIKGVVGSVFLGSLLMAPSVVDAATYHYVNKEII
                     SQEAKDLIQTGKPDRNEVVYGLVYQKDQLPQTGTEASVLTAFGLLTVGSLLLIYKRKK
                     IASVFLVGAMGLVVLPSAGAVDPVATLALASREGVVEMDGYRYVGYLSGDILKTLGLD
                     TVLEETSAKPGEVTVVEVETPQSTTNQEQARTENQVVETEETPKEEAPRTEESPKEEP
                     KSEVKPTDDTLPKVEEGKEDSAEPAPVEEVGGEVESKSEEKVAVKPESQPSDKPAEES
                     KVEPPVEQAKVPEQPVQPTQAEQPSTPKESSQEDNPKEDRGAEETPKQEESTPDTKAE
                     ETVEPKEETKTAKGTQEEDYVGEALVPEQLPEYKVTEGTLVEESTTELDYKTETTEDP
                     TKYTDEETVLRNGEKGSQVTKTTYKTIGGVKTDQVLSTSTEVTKEPVNQQVIRGTKPI
                     EGTTVETREEIIPFETKEQEDDTLKRGTRQVTQEGVNDKKQITETYKTIRGEKTSDAP
                     TITETVIEKPQDKIIKNGTKELEKPTLEWAKTDKDVLKKSATASYTLTKPAGVEIKSI
                     KVALKDNTGTVVKEVTVEENNLQATLDNLKYYQGYTLSTTMVYDRGNGEETEILEDKE
                     VQLDLKKVEIKDIKETRLMKVDENGNETDSSLLETVPENLTSYYLKITTNHNKVTRLA
                     ITNIEEVTEEETSLFKVTASAPDLIQRDSNNSLSQTYTYYIEKPKASQNNVYYNFKDL
                     VDAMQKNPNGEFKLGSDLNATNVPTPSKSYVTGKFTGHLTSVDGKHFSIHNTARPLFD
                     RVEGGSIKNINLINVNINMPWANQLASLAQTVKNATVENIKVTGTIVGNNNVAGILDK
                     LDDAGIMTNVAFIGKVQSVGDKGWNLAGIASEIYRGNLNKAYADVELKGLNTRAGAIV
                     GHLAHDFNPRDVGAWSNVRNSVAKGTIDVARGDVGGLIGKDWPWGTIDNNISLVNVKR
                     GDIFFGSNDMDDEFVSNWIKPNNATVIGVSSGDKTHKQSSKIKEISQVEADKKIKDMG
                     ITADTFEVTEHLVDKLNRRILRDEEYKTIQDYNANRELVYRNVEKLQPFYNKEWIVNQ
                     GNKLTTDSPLMNKEVLSVTAMKGNDFITDLTDADHIMVHYADKTKDIFTISPKDSQVK
                     QVKEYSVAELGEVVYTPNMVVKDRADLISAIEGILSPIELQSDPIYQRLGRTGDNRVN
                     AIKNLYLEESFKEVKDHLNTFVTKLVENEDHQLNTDEAAKRALIKKIEDNKAAVLLGL
                     TYLNRYYGVKFDNFNIKELMLFKPDFYGKNVSVLDRLIEIGSKEDYIKGSRTQESFRE
                     VVAKNTLSGNLHDFLTYNMKLFTNETDINVWFKKAIENNAYVVEQPSTNPAFANKKYR
                     LYEGLNNGQHGRMILSLLNLKDAHLFMISTYNTISFSSFEKYGKDTEEKRESFKSEIN
                     KRAKEQVNYLDFWSRLATDNVRDKLLKSQNVVPTPVWDNHGAPGGWPDRFGHRKDKPD
                     YAPIREFFGRIDKYHDYKYGYGAYAYIFADPQPMDAVYFVMSDLISEYGTSAFTHETT
                     HVNDRMAYLGGHRHRQGTDLEAFAQGMLQTPAEHGHQGEYGALGLNMAFERSNDGNQW
                     YNPDPTKLQTRDQIDHYMKNYNEAMMMLDYAEAEAVLPKVKGDNSKWFKKIDRETRRP
                     MDRNKLSGPHQWDKVRDLIDAEKTTNLETIDDLVNNNFMTIHGNPGNKVFHPEDFGTA
                     YVNVNMMAGIYGGNTSQGAPGSLSFKHNAFRMWGYYGYEHGFIDYVSSKHQGAANKEN
                     NGLLGDDFIIKKVSNNQFSNLEDWKKQWYGEVLTKSKKGFAPIEINGTQISTYEQLKT
                     MFDEAVTKDLTELNDSSIKDKYRNTVVLKSKVFKALLKNTDGFSGDLFTAPQA"
     gene            complement(60864..61427)
                     /locus_tag="VQ540_000394"
     CDS             complement(60864..61427)
                     /locus_tag="VQ540_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HET2544258.1"
                     /translation="MNETQIQRETRQVVEDVLEKTNLKQGVLFVLGLSSSEVLGGQIG
                     KESSQEIGELIVETILGILGSRGIHLAVQGCEHVNRALVVERQVAEQFDLEIVSVHPT
                     LHAGGSGQLAAFKFMQDPVEVEFIKAHAGLDIGDTAIGMHVKHVQVPIRPILREIGHA
                     HVTALASRPKLIGGARAHYPQDAIRKS"
     gene            complement(61543..63234)
                     /locus_tag="VQ540_000395"
     CDS             complement(61543..63234)
                     /locus_tag="VQ540_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET2544259.1"
                     /translation="MKRSSLLVRMVISIFLVFLILLALVGTFYYQSSSSAIEATIEGN
                     SQTTISQTSHFIQSYIKKLETTSTGLTQQTDVLAYAENPSQDKVEGIRDLFLTILKSD
                     KDLKTVVLVTKSGQVISTDDSVQMKTSSDMMAEDWYQKAIHQGAMPVLTPARKSDSQW
                     VISVTQELVDAKGANLGVLRLDISYETLEAYLNQLQLGQQGFAFIINENHEFVYHPQH
                     TVYSSSSKMEAMKPYIETGQGYTPGHKSYVSQEKIAGTDWTVLGVSSLEKLDQVRSQL
                     LWTLLGASVTSLLVCLCLVWFSLKRWIAPLKDLRETMLEIASGAQNLRAKEVGAYELR
                     EVTRQFNAMLDQIDQLMVAIRSQEETTRQYQLQALSSQINPHFLYNTLDTIIWMAEFH
                     DSQRVVQVTKSLATYFRLALNQGKDLICLSDEINHVRQYLFIQKQRYGDKLEYEINEN
                     VAFDNLVLPKLVLQPLVENALYHGIKEKEGQGHIKLSVQKQDSGLVIRIEDDGVGFQD
                     AGDSSQSQLKRGGVGLQNVDQRLKLHFGANYQMKIDSRPQKGTKVEIYINRIETS"
     gene            complement(63231..63968)
                     /locus_tag="VQ540_000396"
     CDS             complement(63231..63968)
                     /locus_tag="VQ540_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET2544260.1"
                     /translation="MTYTILIVEDEYLVRQGLTKLVNVAAYDMEIIGQAENGRQAWEL
                     IQKQVPDIILTDINMPHLNGIQLASLVRETYPQVHLVFLTGYDDFDYALSAVKLGVDD
                     YLLKPFSRQDIEEMLGKIKQKLDKEEKEEQLQDLLTNRFEGNMAQKIQSHLADSQFSL
                     KSLASDLGFSPTYLSSLIKKELGLPFQDYLVRERVKQAKLLLLTTDLKIYEIAEKVGF
                     EDMNYFTQRFKQIAGVTPRQFKKGEDR"
BASE COUNT        19311 a        13918 c        11318 g        19611 t
ORIGIN      
        1 tttttgaaag cagatgagta ttatatgcaa tttctttata taaaaagacc ggattgctcc
       61 gatctttcaa tagttcatat tctcaatttc tattttaaaa atagctaagg ttaacgtcaa
      121 atgactacgc gacctatttc atacgataaa aatcaagcac tagaccagca ggtccttgaa
      181 ctaataagga ctctgttccc caatcggtta cagttggtcc gtgtaaaacc tttataccaa
      241 gctcattcaa ccgtttgtag ttctggtcta catcctcaac ctcgatatga ataatgattc
      301 ctgactgaaa gttttccaaa ggaaccaaat gattttgtga caacataagg cagtgactac
      361 caatcgtaaa ctgagcaaaa ccatcatcag cataatctgc ctttttatcc aaaatatgct
      421 ccaagtcagc acagacttgg ggaacatttg aaacgataat atctaattga tttaaattca
      481 tttactctcc tccataaaaa gaccgaattg ctccgatctt ttaaagttct gctctatgaa
      541 aatcaaagaa taaagtctac aagtttcata tttgattttc ggcgagagga attatttaat
      601 tgcgcgtgat tgcaatcctt cttcttccaa gaagagacgg aatggtacga gttcttctgc
      661 ttcgtatttt tccttgaagg ctttgatagc ttcttctgag tgaagttttg gatccaattc
      721 aagtacttct actggaagtg gacggtgttg agtgatgcga gcatcgatga caacagtttt
      781 accttctttg ttcaatttaa cagcttctgc aacaactgca tcgatgtctt cgatacggtc
      841 aactgtgaat ccaacagctc cttgagcttc cgcaatttta gcgtagtcag cgtttgtgaa
      901 gtctacacca aacaagtgtt tgtttgtatc ttcgtatttg ttcttgatga agccgtactc
      961 agcatttgag aagacaaggt tgataactgg aaggtcgtat tgaacgtttg tgataacgtc
     1021 tgggtagcac atgttgaatg ctccatcacc catgatgttc catacttggc gatctggatt
     1081 gtctttctta gcagcgatac caccaggaag ggcaataccc attgtcgcaa agagcggaga
     1141 tgtacgccac atattcttag gtgtcatgtg aaggtgacga gtagatgttt gagtagtgtt
     1201 acctacgtcg attgagtaga tagcgtcttg atcagcatgt ttgttgattg cattgtaaac
     1261 ttgatacaat tgcaattcac cctcagtttt accttcgagt ttgttcatgt aatcacgcca
     1321 gttttggttg ttcttaacgt ttgcacgcca ccatggagtt gattcaactg ggtttacttt
     1381 gtcaaggata gctttagctg cttgaccagc atcaccaagg attgaagcgt caagggcatg
     1441 acgtttacca agtttgtaag ggtcgatatc gacttggatg aatttttcag tgttcttgaa
     1501 tgcttcgtaa acttcagcaa atgggaagtt tgaaccaagg aaaagaactg tgtctgcttc
     1561 aaagaccact tcgttggctg gtttccaacc aacacggtaa gcagaacctg tcaaaccttc
     1621 atagttccat tcgaaagctt caaagttttt accagttgtg atgattggtg ctttgatttt
     1681 acgtgacaat tcagtaatca cttcaccagc tttaacacca ccaaatccag catagataac
     1741 tgggcgttca gcattgttca agatttcaac agctttgtcg atttcaactt cgttcaaagc
     1801 aggagcgatg aatgagcgtt cgtatgaacc tgaaccgtag tatgagtttt cgtcgatttc
     1861 ttggaaaccg aagtttactg gaatttcaac aacagctgga ccttttttag aaattgcagc
     1921 acggcaggct tcgtcaatta cttttggcaa ttgctcagcg taagctacac gtttgttgta
     1981 aacagcgata ccgttgtaca ttgggttttg gttaagctct tggaaagcat ccatgttcaa
     2041 ttcgttaact ggacgtgatc caaggatcgc taggaatgga gtgttatcca tagctgcatc
     2101 gtaaacaccg ttaatcaagt gagtcgcacc tggaccacct gaaccaactg caaccccgat
     2161 tgagccgccg aatttagctt gcataaccgc tgcaagagca cctgtctctt cgtggcgaac
     2221 ttgtaagaag cggatatctt tgtcttcagc caaagcgtcc atcaatgagc tgagtgttcc
     2281 tgatgggata ccgtagattg tatctacgcc ccatgttttc aatacgttaa gcattgctgc
     2341 agatgcagta attttccctt gagtcataat gataactctc cttcaatttt tttagatttg
     2401 gagaatacga ttacatagaa ttggaaacgt tctccaaatt tttactattc cactgtatca
     2461 tatttatgct gacttttcta aaaatctgct caaaactctc tattctctat tctaatacag
     2521 ttttgaaagt tctgtcattt ctgttttata acaaagaaat ctagtcatta cttttagtct
     2581 attttactaa aatttaacag aagggaactg gtcagaacag atacagaact aaaggccatg
     2641 gctagacctg ccaattctgg gttgagagcc agtccaacac ctgaaaagac tcctgctgca
     2701 atcggaattc cgacaacatt gtagataaaa gcccagaaaa gattgagtag aattcgatga
     2761 aaggttttct tactcatatc aaaggcacga accactccta aaagattatt ggttgtcaac
     2821 accaaatctg ctgactcgat ggcgatatct gttccagctc ccatagcaat ccccacatct
     2881 gctacactaa gggcaggagc gtcattgata ccgtccccaa caaaggctac tttccctgac
     2941 tgttgcagtt tatggatttc atgggctttt tcttctggca agacgcctgc aatgacctct
     3001 tcaattccga tttgatctgc aatagcacgc gccacaccag cattgtctcc tgtcagcatg
     3061 actgttcgga gaccacgttt ttttagctga ctgatggcta gcttagcatt ttccttagga
     3121 atatcttgca aagcaagcaa gcctttgatt tcattgtcaa cagctaagaa cacaactgtc
     3181 ttagcttctt tttctagttc ttctagttta tcttgataag tattagaaat atccatacca
     3241 tccagcattt tagcatttcc aagtaaaact tgttttccat tgattcgccc tgaaacacct
     3301 ttcccgtgca aggactgaaa attttcaaca gtttgaaact caagtccagc ttcactcgct
     3361 cgcttaacga tagcctcagc cagtgggtgt tgagaagcat cttccaagga ggctgccaat
     3421 ccaaacactt ctacttcgtc gccgatgata tctgttacca caggtttccc ttccgtcaaa
     3481 gtcccggtct tatcaaagac aagagtttga actttctgga tttcctgtaa gacagttcca
     3541 tttttgagga gaacccccat cttggcacta cgtcctgtcc ccaccataag ggctgtcggt
     3601 gttgcaagtc ccaaggcaca aggacaggcg ataatcaaaa ccgccactcc gtagagaaga
     3661 gaggacacaa agctagctcc aagcacgacc acactatccc tgagcaagac gaaccaaacc
     3721 caaaaggtca tgattcctaa aatgacaact actgggacaa aaatccctga aatcttatcc
     3781 gtcaagtcct gaatcggcgc acgacttgtc tgagctttct tcacaaaatc cacaatctga
     3841 gccaaaacag tctctgagcc aactttttct gctctaaaga caagcgttcc actatgattg
     3901 atggttgagc caatgacagt atctccaact gtcttgtcca caggcagact ctcacctgtc
     3961 accatggatt cgtcaatact agagacacct tctactacga caccatcaac agcaatcttt
     4021 tcaccgggac gcactcgaat caggtcgcct accttgactt gttccaaagg aacttggaca
     4081 taactatcat cactcaagac ttctgcggtt ttagcttgca agtccagtaa tttctccaca
     4141 gcttgggacg tattttttct cattttttcc tcaaaaactg ctcccaaaag aacgaaaaag
     4201 aggataaatc cagcactttc gaagtaaaca gggagaccag caaagagagc aactaggcta
     4261 tagaaataag ccactagagt tcccagcgca accaaggtat ccatgttggc attgtgcttt
     4321 ttaaaactgg cccaagcact ctggatatat ggcttacctg caactaacat aataggcgtt
     4381 gttgctagaa aggttcccca atgcatgact tgatgactaa tgctacctgt caacatccca
     4441 atcatgagaa tcacaagagg cacagtaaag atactagtaa tccaaaaacg ttgcaggaga
     4501 gatagagatt ttcgagtctt ctcaacgact atatagcttc ccttttgcat cttcatgcca
     4561 caagaaaatt catgtcgccc taattcttga ggtgtaaaac gaatgacttt ctcctcatct
     4621 acgccgattg gttccaagat accttcttct tcaaacagaa tttccttata acagtttgaa
     4681 ggagtagcac gatgaaaggt aatctcagct ggaattccct tttgaagctg gatatgggct
     4741 ggatgatagc ctttttcagc tcggatacgg attttttgaa tgccattttc taagcttgct
     4801 ttcacaattt ctgtcatagt ctccacctac tctacaatca tcttgccgtg catcatgttc
     4861 ataccacaag caaagccaaa ctctccaacc tgctcaggcg tgatttccac tacatactct
     4921 tcccccattg gcaggttcgc atgtacacca aaatctggaa aaacaatttg atccagacat
     4981 ggtgaaggat ccttgcggtc aaagacaatg cgtgctggca ctgatttctt gaggacaatc
     5041 aactcaggag tatagcctcc catgacttcc actcgaatct cttggtatcc gtttttttgc
     5101 tgggcttttt gtccagattt ttcaggcttt ttgaaaaacc aaaacaagat aaacgcgata
     5161 agggcaatac aaataatggt tacaatacta tttaacatga cgtctccttt acatacaatt
     5221 acatcttact tctgttacag cacttgattt cttctctgaa atcacagctt ccaagtcttc
     5281 caagtcagtc tgagtaaatt cacattctac aatcaagtca gccaacaaat tcctaatcct
     5341 acgggaacaa accttgtctt tgatatcttg gacaagtaaa tcccgacttt ggtctagagt
     5401 taaaagggct gaataaacaa aggacttgcc ttcttttttc cgagtcagac actctttctc
     5461 aaccaaacga gccaaaagag tttgaatggt cgacttggac cagtcgaacc gctctgccaa
     5521 aaccctaatc aaatctgtac tggtctgctc cccctgcatc caaataatct tcatgacctg
     5581 ccattctgca tctgaaatct gcattaccat acctccaaaa tctacatttg tcaattacac
     5641 tcatcagtat actcttaaaa tctacatttg tcaattatag aaataatatt ttcttcgaaa
     5701 aatagaattt taatcatttg aaaaacgatt tgcagtcaaa tattactata taaacaataa
     5761 aaatatgcta tactaaagaa aaaagaaaac aaccactagg ggtgcgtaaa gctgagatta
     5821 acgactgtta gatccctctg actcaatcta ggtaatgcta gctgatggaa gtggaaatga
     5881 taatggggac tagcagtctt ctattgcctt tctaaaacag actagcttgt tcttaagaat
     5941 acaaacttca gttggttggg aggttttaga tgacttattt acccgttgct ttgaccattg
     6001 cagggactga ccctagtggt ggtgctggca ttatggcaga tttaaagtca ttccaagcga
     6061 gagatgtcta tggaatggct gttgtaacca gtcttgtcgc tcaaaatacc agaggtgttc
     6121 agctaatcga gcacgtttct cctcaaatgt tgaaagccca attggagagt gtcttttctg
     6181 atattccacc tcaggctgta aaaactggaa tgttggctac tactgaaatc atggaaatca
     6241 tccaacccta tcttaaaaaa ctggattgtc cctatgtcct tgatcctgtt atggttgcta
     6301 caagtggaga tgccttgatt gactcaagtg ctagagacta tctcaaaaca aacttactac
     6361 ctctagcaac tattattacg ccaaatcttc ctgaagcaga agagattgtt ggtttttcaa
     6421 tccatgaccc cgaaggcatg cagcgtgctg gtcgcctgat tttaaaagaa tttggtcctc
     6481 agtctgtggt tatcaaaggc ggacatctca aaggtggtgc taaagatttc ctctttacca
     6541 agaatgaaca atttgtctgg gaaagcccac gaattcaaac ctgtcacacc catggtactg
     6601 gatgtacctt tgctgcagtg attactgctg aactagccaa gggcaagagt ctttaccagg
     6661 cagttgataa ggccaaggcc tttatcacaa aagctattca agatgcccct caactcggtc
     6721 atggttctgg tccagtcaac catacaactt ttaaagatta agaaaaaaac tctctagttc
     6781 ccactttaag ggaattagag agtttttata ctcttcgaaa atctcttcaa attacgtcag
     6841 cttccatctg caacctcaaa acactgtttt gagctgactt cgtcagtctt atctaaaacc
     6901 tcaaggcagt actttgagca acctgcgact agctttctag tttactcttt gattttcatt
     6961 gagtattaat taggaaagaa tgtcatgcaa ctttgttaaa aaggcttgcg tttttgcctc
     7021 aatatcttct gcttgcatca aatcacgtac aacagctaca ccagctatgc cagtgcccat
     7081 aagctgatca atattctccg aagtcaagcc tccaatagca actactggaa tggcaaccgt
     7141 ttggcaaatt gttttcaagg tcgatatcag agtaatgggc gcattttcct tggtggtggt
     7201 tgggaaaatg gctcctgtac ccaagtaatc tgcacctgat ttctccgctt ccagagctct
     7261 tttaaccgtt ttagcggtga caccgaggat tttttcagga cccaagactt tgcgagctac
     7321 cgaaactggt aattcatcat ctccgatatg cagacctgct gcatcaaccg caagacaaac
     7381 atccaaccga tcatcgatta tcaaggggac ctgataggca tctgttattt ccttgacttg
     7441 ttttgccagt tgataatatt gattggttgt gagatttttt tctcgcaatt ggactatggt
     7501 aacccctgaa cggcaggccg tctcaacttt tgcaagaaag ctttccacgg aatcttgata
     7561 gcgattggtt accagatata gtctaagtgc ttctctattc ataaacctct cctttgatgg
     7621 tatctagcca attttcatct cttcttagga gcgaaagctg attgagtact tggtaacgaa
     7681 attcttccaa tcccattcct tgaacaacta ttttctcagc agcgatattg agataagaga
     7741 ctgctaagca agaagcttca aaaccagtct ttccttggct gagaaaaacg gctgttaagg
     7801 ctccaaccaa gtctcctgtc cctgttatcc agtctaattc agtacagcca ttctccagta
     7861 cagcaacttg attctccgaa acaataaggt ccttggggcc agtaactaag aaagacatac
     7921 caggataggt ctgacaccag tctttcaaga cttgaagcaa atcctccgtt tcttgatctt
     7981 tagcactcgc atcgacccca acgccgtggt gctttaatcc aacaagactt cgaatttctg
     8041 acatgtttcc tttaaggacc gtaggtctat agtctaaaag gtctttaact aagctcttac
     8101 gaatggatga agtcgttacg ccaaccgcat ctactaccat cgggagagaa gattggtttg
     8161 catacgaagc tgccatgcgg attgcttttt ccttctcagc tgacaaatgc cccaaattga
     8221 tgaagagagc ctgactttgc ttagtaaaat caagaacttc acggggatca tctgccatga
     8281 caggtttgca tcccagagcc aaaatcccat ttgccagcat ctcacaagaa atctcattgg
     8341 tcatacagtg aatgagggaa ctagagccta taggaaaagg atttgtcaat gcctgcatca
     8401 gtctatcctt tcagcaaaga aatatccttg cactttttta aagaattcct gcttgattaa
     8461 aaatctaaat gcaataaagg aaatcgctgt accaatcaag gttgctccga aaaatcgagg
     8521 agtgtagata aaccaactaa gcttagcagc cgatcctgta aagagcacca taacaggata
     8581 ggaaacaata gaaccaataa tacctgttcc cacaatttct cccaaggcag aaaagtaaaa
     8641 ttttcgaccg tacttataaa agagacctgc tagaagggct ccaaaagtcg ctcctgtgag
     8701 agctaaaggc ggaatccctt gagtcgtcat acggataaag gctgtcactg tagccatagc
     8761 caaggcataa acaggtccca tcatgattcc cgctagaata ttgactacac tggacatcgg
     8821 tgccattccc tcaatccgaa agataggtgt aaggactaca tcaagggcaa tcatcataga
     8881 taaaatggtc aatttgtgaa cttgtagttg gtgctttctc atgtttctat tcttctcctt
     8941 tttctaaaga ctgtaaatcg ctcttccatg tctggtgttg gtaagccatc tcccaaaact
     9001 tggcttccat atgaacactg atgtggaagg catctagcat tttttgctta tctgtctcat
     9061 cactttctcg ataaagctga ttgaccagtg ctccctcctc tctgatctgt tgctctaact
     9121 catccgtaat ataagtttca atccattgtt gatagagagg atttggtgat ggtttaagat
     9181 taagtgattt gcctatatca tggtataacc aaggacaagg aagcaagctt gcaaaagcta
     9241 tggctaagtt cggttctgca aattgcctat aaatatgaga aatgtaatga taacaggttg
     9301 gagcgattgg atgttgctcc atttcctggt cgttgatttc caattccttg aaaaattgtt
     9361 ggcgaataaa taactcaccc tccactaaac cctgagcatt ttgtttcaag agtcttttca
     9421 tctcttggtt tgaagtctta tcagccaaaa gatgatagat ttctgagaaa gccttcagat
     9481 agtaggcatc ctgaatcagg taatagcgga aaatggcagg ttctaaattc ccctcttgta
     9541 attgtaaaat aaagggatga tgaaaggaag cctgccaagc tttcttggat aattccatcg
     9601 caatatctgt aaattccata ataactcctt tataaaaata gactggtttg aagcaataaa
     9661 aagaaaagca ggtagattaa ttttgttttt ttaggaatat aaaaagtccg atagctattc
     9721 ttcaactgtg catgttcgtc atatccgtaa gcagatagag ctctcaggta aagatggcgc
     9781 cacctaaaga ctgtcatcag aaccttactg taaatcaagg gcgaccaaaa atgtagtttt
     9841 tgaccacgta ataggcaagc ttctttgagg gacttgattt cttgctgaat gagaggaaaa
     9901 gaattgaata ccacaatcaa ggcataggac caagagcgtg atagcccctt ttgagccaag
     9961 tacaagagaa gctcttttag tgaaatagag gaaacaaaga caaggccgat acaaactgtc
    10021 acaaaggccc tcgttccaag catgactgcc tgtgaagcat ctccgtgtaa ctgaactgcc
    10081 cagtagttgg caaaagatgg gaaaatggca agtatgatca tccaagctaa cattttaaat
    10141 cgacggtaat agagcataaa gagaatacaa aatgcgacta ccgaaagatt cagagcaatc
    10201 gaaggaatga aagatgtttc caaggataaa atcagcaaga agagactgat aatcggtgtc
    10261 tgggttgcta ctttgaccat actatctcac ctccccttgg gtattgctac tctgagatgt
    10321 aagtggtttg gtaatggtca cttctttcac atgccgaaga ccctgactag tcatctcaat
    10381 ccaataatca accacagaaa tcaaagggtc taaacgatga ctaatgagca gaaaacttct
    10441 tccttgattc ctctcctcca caatccactt gcaaaaataa tggcaggctc tatcatccaa
    10501 acctgcaaaa ggttcatcta gcaagatcac ggaagcctta ctggtcaaga tggtcaggag
    10561 ctgaagaatt ttttgctgac caccacttaa ttgataggga ctcttatcga ctgcctgctc
    10621 caaatcaaaa tatcgtaaag cttgaaaaat ccgctgattt ctttcagaat caggtccatc
    10681 taattgaagc tcctctcgca gactgactcg gataaactgc ttctcagctt cctgaacaac
    10741 accagtcaga tcacgataca aactcttttt ctttttcagg accgaaccct tccaagtaat
    10801 gctcccctta tacttttgaa attgaagaat agaccgaaag agggttgatt tcccgacacc
    10861 attgtcaccc aggatacagg aaatcccttg atagaatgtg aaatcagcaa ttgaaaagag
    10921 ggggcgatta ccaagctcac cagtcacacg gttcatatgg aatagttccg ggctagaagc
    10981 aacttccttt gaagcaacct gtgtcatctc ataggaaggg atttgaaaca cttcccttag
    11041 ttttccgtct cttagctcca ccatatggtc gatataggct ttatagtcag ataaatcatg
    11101 gtcgcacaaa ataactgtct tcccatcata gaccaactct tttagaatct ccaatatctc
    11161 gattctgctc ttgcggtcaa tggaagcgaa gggctcatcc aagagataga ccctaggatt
    11221 catggcaaag aggacagcca gcgctgcttt ttgcttttcc ccacctgata agtgatggat
    11281 gagacggtgc aagatgtcct tgcaacgaca ttgctggaca acctctgcta ttttagaatc
    11341 aatttcctga aggtgatagc cgatattttc catggtaaaa accaactcct caaacaagct
    11401 ctccatggta aattgatgat taggattttg caagagaata ccaaccgtct ggacacgttc
    11461 gacgatagaa agctgactga cctcgctccc atctatcagg acttgaccgc tatagggaag
    11521 agaactaact tgggcaatca tttgaaagag gctggatttt ccagacccac tactcccaac
    11581 taacaaggta aaggcttgcg catgaaaagt aaaatcaaac ggctcagaga agattgggga
    11641 ctgaatcgct cgtagttcca gacccatcta tgcttttcct ccagttgcaa actgatgata
    11701 gagtttgaca atggcacgaa ccaagatggt acagaagaaa taaacagaaa taaaacgtac
    11761 cacaagcaag gaaaggacaa acggaaggga aaaggcgtag taacctaact taatgtattc
    11821 atagacaaag ctaacaagcg taatcccaat actattagca gttagagaga gccaactttc
    11881 atagcgattc ttagttacga taaaaccaaa ttcacttccc aaaccttgaa caaagccaga
    11941 caaaagagct cctagaccaa attggctacc ataaaggact tcagcaagcg cagctagcac
    12001 ttctccaatc gttgcacttc cgactctcgg aacaaagatg gcagcaatgg gcgcagccat
    12061 acaccagaga ccgaagagga tttcattggc aaaggcctgc aaaccaagag gtgttaagag
    12121 tagactgaga atattataca catatcctga accaacgaaa accccaccaa aaaagataga
    12181 caagaaagca agcaagataa catcttttaa ctgccatttt ttcaacataa aaaactcctt
    12241 tttttaaaga aaagtggggc actcaagaag accgacctaa atactttgta tagcagactg
    12301 aatttagaac agtacacaag aacactaaaa tatttctaga aattaatttg aattttctaa
    12361 ttgatttgtt cgcatcttat ttcaatctac tatatcatct tcatccagtt tcgtaaaaga
    12421 aaaaactcta attacagata caaattagag ttcagcttac aagattagac agttcttttc
    12481 gacatacgaa aaaaacattt cacatttccc ttcgccagtc ttaactgtat caggttcaat
    12541 gggtatcatc tcagcctaaa gcaccccaaa tgtctttatt atttaattat gtgattatta
    12601 taacacacat tttatactag ttcaagaaat tgaactggaa atacagcctt gcactcacaa
    12661 agacagcaga tctttctttt gcaaaaaaca aatgacctgt ttgatgaatt agccattcaa
    12721 gctgaatctg gacatagctt tttaaaaaag gaaaatccta cttacttaga atccaaggat
    12781 agatatctat tgttcactca tttcccgaac agttttttct atattttttg catacgatat
    12841 tgccgaaatg attgaaacgc catccatatt ggtctttata atgtctttaa tatgtttcgt
    12901 ctgtatccca ccaattgcaa ctaaaggcat ttgtggcaat agttttctca tcaattcaag
    12961 accttcataa cctatagtac caccagcatc atcctttgac tgggtaccaa atacaggccc
    13021 aacacctaca taatctacat attcaacttt tgattgttga aattcttctt cgtttcttat
    13081 agaaagacca attattttat ctggcatcaa ttttctaatt tcatcaacac caatatcatc
    13141 ttgacctaca tgtacgccat cggcgtcaat ttccattgct aaatctatat cgtcattaac
    13201 gataaatgga acattgtatt ttttacaaag ttctttaatt tggatagcta gctcaagttt
    13261 ttctaagcct tctaaagcac cctcaccttt ttctcgaaat tgaaataagg ttataccacc
    13321 ttttaaggct tcctcaacga ctgtatatag attttttcct tggcaagtag tcgttccaca
    13381 aataaaatat agttttagta attctttatg aaacatctta cttcactctt ttgaattcct
    13441 ttacatcttc atctgtaatc tcgtataagg catttataaa ttcaacttta aatgtcccag
    13501 gaagatgtcc atttggacgt ttttctgcca tttctccagc gatattgtaa accaacattg
    13561 ctgtttctaa tgatttcaat tcttgacctt tttctagtcc gataaagctt gctactacag
    13621 ctcctaataa gcatcctgtc ccaatgactt tcggcatcat agcactacca ttatgaatca
    13681 ttaccacttc tccattaaca gcaatggcat ccacttcacc tgttactact attggaatat
    13741 tgaacttctc atttgctgct agagcaattt cgtcaatatt atctacgccc gcactatcta
    13801 ctcctttaga tgccacatct attcctacta aagaggcaat ctcgccagca tttcctctaa
    13861 tcgctgctag tttataattg ttgattagat catctgctac tttttttcta tattctcctg
    13921 ctccacaggc tacaggatct aaaactgctg ggacattata tttctctgca attttcagag
    13981 cagcttggta taatttccaa ttttcatctg tcaatgttcc tatgtttatt aataaaccac
    14041 cagcatactt taacaaatcc tctaaatctg ctggaaactc actcatggct ggtgaggcgc
    14101 ccagtgctac taatccattt gctgtgaaat tttttactac atcattggtt atacaaatga
    14161 ccaatggtgc tttttctttt aataatttta aacttgtcat attgaaatcc ttccttttca
    14221 ctttatacga tctactgatt tcgatttatt tctatctttc gttaagaatt tttttcattt
    14281 acattgaatg atttatactc aatgaaaatc aaagagcaaa ctaggaggct aaccgcaggt
    14341 tgctcaaaac actgttttga ggttgtggat agaactgacg tggtttgaag agattttcga
    14401 agagtcttac ctcatcaaat ttgtaaatat catgagcctt ctctagacat cgtaaccaat
    14461 atcaaaaaaa gctaattcta aagcgactgc ttgattccag cgttgctgaa gttctgtcaa
    14521 atcttctcga tttttatcga cacgattgag ttcgtcaacc agaaattgaa cccactctgc
    14581 aaagaaagga cctctgtgga gattgatcca ttccgaatga atatagactt caggtaaagc
    14641 caaatcttta gaaccccagt ctaaatagag accttctgca atgaccagca tgaccaaaag
    14701 atgggcatag tctgatgaag ccaccgccga atacattaga tcctgaaagg cttttgttac
    14761 agggtgcaaa gtcacttcta gatagtcatt ctctgctact tttaactctt taaaagcctt
    14821 ttggaaataa ccatcttcat ctgcttcaag aaagcctagt tgcttggcaa aacgaagctt
    14881 ggattcaagt ttatctgcgt gagctacgca ggcacccagc atggataaga aggcatcaaa
    14941 gaagtgataa tcttgaatca gatagtcctt taagacctta ttctcaattg tccccgcaaa
    15001 aagttcctta acaaaacgat gattgattgc agcctgccaa tccttctgac tgctttttaa
    15061 taattctcca acagtcaaac ctggctgaaa tgcatagtct tgtgtttcca tatttacttc
    15121 tcctctcttt acttgttagt aattaataaa acaccaagaa atatcaagca aaatcgtaat
    15181 tccacttgat ccttttaaag cacatcgaga gcatttgcag agagctaact aaacaagcct
    15241 atccagttta tataaacaaa aaactccaat tacaatcaag aattagagtt gacttacaag
    15301 attagatcgt tcatttcgcc atacgaaaaa acgtttcaca tttcccttcg ccagtcttaa
    15361 ctgtatcagg ttcaatgggt attatctcag cctaaagcac cccaaatgtc tctattattt
    15421 aattactgaa ccagtatagc aaaaaatgaa agccctagca agatatttga ccgaaaaata
    15481 tctttatata taatatattg aaactagaat agtacacctc tacttctaaa acattgttag
    15541 aaatcgattt gactgtcctg attgatttgt cctattctta tttcatttta ctatagtttt
    15601 cgatagcaat ttattcttcc aatacacgaa gaaaaacctc cacattcagt ggaggcaatc
    15661 tgttttatca atacaatttt aagtcacgag ggtcaactgg gaaggttggg ttgtatggat
    15721 tgtgacggag cttaaagtgt ttgacatctt caatggtctg agctccagac aattgcataa
    15781 ctgtcttcaa ttccgcattc aagtgttcaa agacttgacg cacaccgaca ctaccaccga
    15841 gagccaagcc ataaataaca gggcgaccaa tagctaccaa gtctgctcct gaagccaagg
    15901 ctttaaagac gtgttgacca cgacgaacac cagagtcaaa gacaatcggc acacgtctat
    15961 caactgcttc tgccacttct tgaagcgagt caaaggcagc tggtccaccg tcgatttgac
    16021 gaccaccgtg gttggttacc cagataccag aagctcctgc agcaagtgaa cgttcaacgt
    16081 cctcacggca ttgtggtccc ttgacataca caggaagacc agagtattca gcgataaatt
    16141 ctacatcgcg tggagacaag cgttgtttag ctgatttgta aacaaagtcc attgatttac
    16201 cagcaccttc tggcaggtat tcttcaacaa tcggcatgcc aactgggaag acaaaaccat
    16261 tacgcttatc cacttcacga ttccccccta cagtagcatc tgccgtcaag acaatcgctt
    16321 tataaccttc agccttcaca cggtccatga tgtggcggtt gataccgtca tccttactaa
    16381 agtaaaattg gaaccaatgg ggtgtccctt gaagggcttc agaaatctct ggaaggtcaa
    16441 cagtagagta agagctggtt gtataaagag aaccaaactc atgcacacca cgcgcagtcg
    16501 ccacttcccc ctgttcattt gccaatttat gagccgcaac aggcgccata atgattggtg
    16561 aagatagttt ttcacctgca aattcaatct ctgtacttgg attttcaaca tcgcaaagtg
    16621 tatgaggaac gatgagtttg tggttaaagg cgcggatatt ctctcttaaa gtgaaagtat
    16681 cttccgcccc actagcgata tagccaaatg ctgctttagg aataacttgt tgcgccattg
    16741 gctccaaatc ataggtattg atgaagtcta catgaccttc tgcattgctt gttttgtatg
    16801 acataaaatg ccctccttga ttaagtaagc gtttgctttt tactacacaa ctataataac
    16861 tcttttttca atcattttca agagttttgc ttaaaaacca tcttattttt tcatacaata
    16921 tactagccct actttcctta aactctaaac tttagtctat attaagtgaa tcgttgagat
    16981 tttttgctgc caggcatttg aactactttt ttatttgcgg attctatcta ctaatactat
    17041 aaaaaaacaa gtgaataaga caccagaaca tcctctaata ggacctatgg acttatatca
    17101 gtcccatata tactgtttaa gcaagatact atcctagttg acgctaactt cctatcccac
    17161 ttattaattt tttatttata gtgaatctga acaaatcaat tggggaatcc aagtcaattt
    17221 ctagtacttt ttgaacagtt tcagcgtact atcgtaaaat gaaataaaac atgcacaaat
    17281 tgcttaggga atttaaacca atttctaaca atgtcttaga aatcaaagtg tactatttca
    17341 acttcaatat actacacttc attttctcct taaattcagt ctctttttga atcaaaaaat
    17401 cccctggtaa gagccagagg ataagaattt atttcattgt tgggaagagc aatacatcac
    17461 ggatagttgt tgtatcagtg aggagcatgc agagacggtc gataccgatt cccaaaccac
    17521 ctgttggtgg cataccgtat tcaagagctt caatgtagtc atagtcgatg cctgtcgctt
    17581 catcatcacc aagttctttg gctttagctt gggcttcaaa acggctaagt tggtcgattg
    17641 ggtcgttcaa ctcagtaaag gcattaccgt actccttagt catgataaag agctcgaaac
    17701 ggtcagtaaa gcgttggtct tcaggatttt tcttagcgag tggagataca gctactggat
    17761 gtccatagac aaaggttggt tggattaaag tttcttcaac aaactcttca aagaaggcat
    17821 tgatgatgtg accaacctca gtgtagtgtt tctcaactgg aactttcttc tcagcagcga
    17881 tagttttagc ttcttccaaa gtcatgtctt gccagaaatc gacaccagta atttctctga
    17941 tagcatccac catatgaaca cgcttaaatg gttcgttaat cttgatttca gtaccttggt
    18001 agttgactgg gccatcacct ttgactgatt tagcagcgtg ttggataatg ccttcagtca
    18061 agtccatgat gtcttggaag tctgcataag cttggtaaac ttcgatagaa gtgaactcag
    18121 ggttatgagt agcgtccatt ccttcgttac ggaagatacg gccaatttca tagacacgtt
    18181 ccataccacc cacgataagg cgtttcaagt gaagctcagt cgcgatacga agcaccatgt
    18241 caatgttttg ggcattgtgg tgggtgataa atggacgggc agcagcacca ccggcttcat
    18301 tatgaagaac aggtgtttcc acttcaagga atcctttttg gtcaaggtaa cgacggattt
    18361 cagagatgat ttttgaacga gtgacaaagc gttcaaagct ttcacgatta gaaatcaagt
    18421 caaggtaacg tttacggtaa attgtttcaa cgtctgtcaa accatggaat ttctcaggaa
    18481 gaggacgaag agccttagac aagtgtgtga tgtgggttgc cttgatagag agttctccca
    18541 tatccgtacg catcacttca ccttcgacac caaggaagtc accaaggtct gcttttttga
    18601 agatttcgta gttttcttca ccgacagcat ccttacgaac gtagatctga atctggcctt
    18661 cgcggtcttg aaggtgggca aaaccaactt ttcctttacc acgtttggtt atcaagcgtc
    18721 ctgcgatagt agctgtttcg tttttatcgt gtaattgttc tttatcgagg ttggcatatt
    18781 tatcttttaa ttcttgtgaa tttgcagtac gttcaaaacg ttttccgaaa ggatcgattc
    18841 cttgttcgcg gagcgcagcc attttttcac ggcgaacgat ctgctggtca tttagttctt
    18901 ccatatgttc tgtagacatg ggatcctcct agttttactc aaaattgaat acgatgagtc
    18961 attttttgcg atactcccat tttatcataa ataagcaaga aattcacgga taatctttaa
    19021 aaactaaaaa gaacctgacg ctaaaatcac tggaaagaag tgaaagtatc tcccgcccca
    19081 ctagcgatat agccaaatgc tgctttagga ataacttgtt gcgccattgg ctccaaatca
    19141 taggtattga tgaaatctac atgaccttct gcattgcttg ttttgtatga cataaaatgt
    19201 cctccttaat aagtaagcgt ttactttgtg tattacaaaa atatcttaac tctttttcaa
    19261 aacttttaaa atattttgtt tggaaatttc agaaatttta tgtctatgat aaaaatcctt
    19321 ataacggcaa taaaaaatag atattatcca aagaagattt taagtgctac aataactgta
    19381 ttatttctag atgggaggtt ctatttttgg attgatccat tgttgaacaa tatctaccac
    19441 tatatcaaaa ggcattcttt ctgaccttgc atattgcagt ttggggaatt ttgggatcct
    19501 ttctgctcgg tttaatcgtt agtatcatcc gacattatcg aatccttgtt ttggcgcaag
    19561 tagcgacagc ctacattgaa ttgtcacgta atacgcccct tttgattcaa ctcttctttc
    19621 tctacttcgg tcttccccga atcgggattg tcctatcttc agaagtctgt gcaacgcttg
    19681 ggcttgtctt tttaggaggc tcctatatgg cagaatcttt ccgaagtggg ctggaagcca
    19741 tcagtcaaac ccagcaggag attggcctcg ctattggtct gacacctcta caggtctttt
    19801 actatgtggt tcttccgcaa gcaacagcgg tggcactccc ctcctttagt gccaatgtca
    19861 ttttccttat caaggaaacc tctgttttct cagcagtggc tttggccgac ctcatgtacg
    19921 tcgccaagga tttgattggt ctctactatg agacagacat tgcgctagct atgttggtag
    19981 ttgcttatct gatcatgctg ctacccatct cactggtctt tagctggata gaaaggaggc
    20041 tccgccatgc aggattcggg aatccaagta ctctttcaag gaaataatct cctgagaatc
    20101 ttacagggat tgggcgttac gattgagata tccatcctgt ctgtcctctt atccatgatg
    20161 ttcggaacag tcatgggaat catcatgacc tcccattcta gaatcatacg atttttaaca
    20221 cgattgtatc tggactttac ccgtatcatg ccccagctgg tgctactctt catcgtttac
    20281 tttggcttag ctcgaaactt taatatcaat atctcaggtg agacttcagc tattatcgtt
    20341 tttaccctct ggggagcagc tgaaatggga gacttggtac gtggagctat cacttctctc
    20401 cctaaacatc agtttgaaag tggacaggca ctcggcttga ctaatgttca actttactac
    20461 cacatcatca tcccacaagt cttaagaaga ctgctaccgc aggctatcaa tcttgtcact
    20521 cggatgatta aaaccacttc attagttgtt ttgattgggg ttgtggaagt gaccaaagtt
    20581 ggacaacaaa tcatcgatag caatcgcctg accatcccaa ctgcttcatt ttggatttat
    20641 ggaaccattc tagtcttata tttcgcagtt tgctacccta tttccaaact atccactcac
    20701 ttagaaaaac attggagaaa ctaaatgtct gaaactatct tagaaatcaa ggaactaaaa
    20761 aaatccttcg gagacaatcc catcctccaa ggactttctc tagaaatcaa aaaagggaag
    20821 ttgttgtcat cctagggcca tctggttgtg ggaaaagtac cctccttcgt tgcctcaacg
    20881 gcttagaaag tattcaaggt ggagatattc ttctggatgg tcagtctatc gttgaaaata
    20941 aaaaagattt tcacctagtt cgccaaaaga ttggcatggt ctttcaaagt tatgaactct
    21001 ttccccatct ggatgtctta caaaacctca tcctaggccc tatcaaagct caaggaaggg
    21061 acaagaaaga agtaacggaa gaagctttgc aattactaga gcgtgtcggt ttgctggata
    21121 aacaacatag ctttgcccgt caattatctg gtggacagaa gcaacgtgtt gcaattgtcc
    21181 gtgccctcct aatgcatcca gaaatcatcc tttttgacga ggtgactgct tcgctggatc
    21241 cagaaatggt gcgtgaggtg ctggaactta tcaatgattt ggcccaagaa ggccgtacca
    21301 tgattttagt aacccacgaa atgcagtttg cccaagccat tgctgaccgg attatcttcc
    21361 tcgaccaagg gaaaatcgct gaagaaggaa cagctcaagc cttctttacc aatccgcaaa
    21421 ccaaacgagc ccaggaattt ttaaacgtct ttgactttag ccaattcggc tcatatctat
    21481 aaaggagatt cttatgaaac tattcaaacc actcttaact gttttagcac ttgcctttgc
    21541 ccttatcttt atcactgctt gtagctcagg tggaaacgct ggttcatcct ctggaaaaac
    21601 aactgccaaa gctcgcacta tcgatgaaat caaaaaaaaa gcggtgaact gcgaatcgcc
    21661 gtgtttggag ataaaaaacc gtttggctac gttgacaatg atggttctta ccaaggctac
    21721 gatattgaac tagggaacca actagctcaa gaccttggtg tcaaggttaa atacatttca
    21781 gtcgatgctg ccaaccgtgc ggaatacttg atttcaaaca aggtagatat tactcttgct
    21841 aactttacag taactgacga acgtaagaaa caagttgatt ttgcccttcc atatatgaaa
    21901 gtttctctgg gtgtcgtatc acctaagact ggtctcatta cagacgtcaa acaacttgaa
    21961 ggtaaaacct taattgtcac aaaaggaacg actgctgaga cttattttga aaagaatcat
    22021 ccagaaatca aactccaaaa atacgaccaa tacagtgact cttaccaagc tcttcttgac
    22081 ggacgtggag atgccttttc aactgacaat acggaagttc tagcttgggc gcttgaaaat
    22141 aaaggatttg aagtaggaat tacttccctc ggtgatcccg ataccattgc ggcagcagtt
    22201 caaaaaggca accaagaatt gctagacttc atcaataaag atattgaaaa attagcaagg
    22261 aaaacttctt ccacaaggcc tatgaaaaaa cacttcaccc aacctacggt gacgctgcta
    22321 aagcagatga cctggttgtt gaaggtggtc attaactctt aaaagggact ggattttaag
    22381 ctccaatccc tttttaagat tttacctata acatcctgag tctatctaag atgttcaatc
    22441 tgaacacagt gtacatactt tatcttctat tgcatatact ttatcacata agatacgaat
    22501 atcctcttca ctatgactag caatcaaaat tgttgtccct ttttcactag agagctttct
    22561 aaacaatgtt ctcatatttt ctacacttga tttatccaag gcattcatag gttcatctag
    22621 taaaagaata gagggattct ccatgattgc ttgagcaatc cctagctttt tcctcatacc
    22681 tagcgaataa gttttaactt tctggtcttt ttgctcatat agaccaacta ttttcagtgt
    22741 atcattgatt tcctgattac caactactcc tcgtatgctt gccaaatatt gtaaattctt
    22801 aaagccacta taataattta taaaaccagg ttcttcaatc aaagctccca aattagctgg
    22861 aatttttctc tcaggaacaa tattttcccc attgattaac acttctccat aagacggact
    22921 atataaacca gctattaatt taaacaatac acttttccct gagccattcg caccagtaat
    22981 tcctataatt tccccctgtt tacaactaaa gttaaggttt tgaaaaacac atgtcttttt
    23041 taatttcaac tcaatatttt ttaatataat tatttcattc attctataaa cctcctcttt
    23101 tgacgagtga aatagaaaat gctttgaaaa agaaagacta aaaatagcaa ctgaagaaac
    23161 aaatctcccc ctacatcccc attccctcga ttcaaaatat aaaatagata attagttcga
    23221 tttcctacaa atagaccacc aaacacaatc atgagtaaaa agaaactaac gcaagcaaag
    23281 ttcatttgta cattcgctcc tagtgcgtat aacataaagc aaaacaagac taacacacaa
    23341 gcattcaaag aatcaactat aaacaaaact cctatatccc agtttggtaa ctgtaacata
    23401 aattgaatca ctagaacttt taccatgatt aaaatgagtc cataaagaaa acaggtccaa
    23461 atctgatacc taatccagag cttaatagaa gaaaatcgaa tcacttccat aaagaaatcg
    23521 gatgctcttc tacgatatac aactgctaga aaaaatgtat gaataataaa ccaatgaagc
    23581 aaccatatag ataagactaa aaaagagttt tgactcagat taggcccttt taaaatttct
    23641 ataacaagtc tatcatttcc ttctaaccaa taccataatc ctaaacaaat caatatccaa
    23701 aaaagaacat aaccccaaaa gtacttggta tagattatct tattcaacct ccacatgtga
    23761 ctacttaact ttcccatttc caacttttac actctcctcc agtttctatg aacagaaaat
    23821 acagtcaatg gaattatgat agatagtaat gtaagccaat aaatcaatgc atacggattg
    23881 gaatttacca tatactgaaa aattggcaat aatccaatta tcccattgtt caactgataa
    23941 atccagaata aggattctac aaataaaaaa gtaaacagaa atactaagct catgtttgat
    24001 tttttaaacc aagaaaaact gctaatagta agtaaggata aaaagaaata gtatgctata
    24061 taagagaaaa aaaatcctat aaagaaacta gcattgtttg caatacttat accataaaat
    24121 tctcttaaaa aatcaacctc ctttatctcc aaagagaagc taaaaccatt actaaatgca
    24181 attagaaaaa tcaataaaaa taaagtcgcc gtccaaatcc ccgtactaag agctgctaat
    24241 ttgaaactaa aactggtaaa gtgcttaatt gatttcagac gaatgcgaca ctccaaccta
    24301 ttaaaatagt tattcatcaa ataaaaaaag aacaatatat atgtgaacgg aaagcaatat
    24361 actccagtcg tcatatcttg aagtaaaact aaaatccatt ctaatacatt tggatggatt
    24421 gaatattggc gacagcgcaa taaatatact gtactagata aaacacagga tagcagtaat
    24481 ataaaataaa ccaatactga taaaaaatct tttttgtaaa attgaacaaa ttgtttcatt
    24541 atacatagtc ctctgaatgt agaaaaaatg taccataaac aaccaaacaa ctaacaaata
    24601 aaataaaagc aagatgccca ctaactaagg aaagactgat atctttctga tatcccaaag
    24661 ctaatgttgt cacaggttct aagtaagata gccctaaaat agcccaaaaa ataccaccaa
    24721 ccatcatata ggcaactggg atgaaaatag ctcctatttt tttcttcact agcaaagcac
    24781 tagctagtcc aaaaatagag aacacagcgc cccaaactcc ataccagaga gtcgtcacaa
    24841 gactatagag caactgatta gaatcaaata attcttttaa ggcaccacta taatctccaa
    24901 tataaatttc ctgataagga gtcactaaaa gattaattcc taataataat aaatagggga
    24961 gaaaaaagac tagaaaagaa gaaataattg cagtactacc tacaatagcc agatacttct
    25021 ttttagaaat tcggcacaat tgtgctgtta gaaaatgact ctcagcatcc tctattatct
    25081 gactagaata gggcagtgta cagataagtg cagctactag gctaatcggt gaaaatcctc
    25141 gaatagaaga agcggcaaaa aaaatcgata aaccttcaat tttataaata ccattgaaag
    25201 caaggaaatt tcctaaactc atgcaaagaa gggtcaaaaa taaagacata taaaatcgag
    25261 gtgattgaac gactcgtaca agattacaaa tgaaaaattc catccttact cctccttata
    25321 ataaaaatag ggtgtagcat tcttttttca tgctacaccc acaatcaacc atctttaagg
    25381 cttactctga caagtaagtt aataagaatc tggactccaa gaacctgaag tatgaattct
    25441 tacatgattt ccaaattgtg gcgccatagc taatctagta ccagaaccaa tataattgtc
    25501 accacctcca ttatagtaca tgacaatcct agagccagac cccaatgaat ataccggggt
    25561 aatatctgac ccactatagg cgctacgaat agaggtattt aaccttttac cgccaccagt
    25621 gctgtcacta ttattaattc cagcagaggc gttttctttc tcaagctcac tagttgtatc
    25681 cgaaccccaa cgcggcaacg ttaaatcata atttccaatc tgtctagcta aaactgtagg
    25741 gagaaacaaa ctagatgcaa ttgtaactac gcaaaaaagg aatatatttt tcttcttttc
    25801 atgacatcgt cctcttaaga agtgataaac aagatagttg attgatcaat ttgatacata
    25861 ttacattttc attatatcaa taaaagaaag cgttgtcaat tattttattt aaaatattgt
    25921 catattttaa ataaaatggt aaaagagact cggtagcctc gtctctcttt atcttactga
    25981 cctaaccttc ttgccaattt tcttggtctt ctttaaagcg ttttagaaga tcaaggccct
    26041 ctggcgtgat gtaaccttct tcttgggcta gatggataag ctctctatag tttgaaagcg
    26101 tcacaagttt aacaccagca tctgcaaagt tcttatctgc ttttggcaat tggtagctga
    26161 aaatcgctac aactccaagt acatctgctc cttctcgctt ggctgctgct acagcttcaa
    26221 gaactgaacc acccgttgaa ataaggtctt caaccactac cattttttga ccttgagcta
    26281 cgcgaccttc gatttgatta ccagctccgt ggtcttttgg tttgctacgg atgtaggcaa
    26341 aaggcaagtc catcttatca gcaataatgg ctccgtgtgg aatccctgct gttgcagttc
    26401 ctgcaatcac ttctacttca ggaaaggctt ctttaatagc ttccacaaaa ccattttcaa
    26461 ttagggtacg agtttctgga taggctagtg tcacacgatt atcagtgtaa atcggtgact
    26521 tgataccaga tgcccaagtg aagggttcct ctggtttgag gtaaacggct tggattttca
    26581 agaggtggct agcgatatct ttagcaagtg tcatggtatt ctccttttat ttttctaatc
    26641 tagttcttta attccagttc tgtgtccatt catccttgat ggcatgataa gctgcaacag
    26701 gatcctcagc ttgggtaatg ggacgtccca ctacgatata gtcactgccg atttgatagg
    26761 catcagcagg tgtcatgact cgtttttgat ctccaactgc aacaccagct ggacgaatcc
    26821 ctggtgtcag acagataaaa tctggattgg tagcctgctt gatgacttgt acttcctgag
    26881 ccgagcaaac aacaccatcc aagccagctt cagctgtctt cttggcatag tgaatcacag
    26941 actcttgcag actggtttgg atattttgaa actcctgcat ctgagcttct gacgttgatg
    27001 tgagctgagt tacagcgatc aatttggctt gactcccaag accttcacgc gccgccttca
    27061 tcatctctac accaccagcc gcatggacat tagtcatatc gacaccaagc tgagacaaga
    27121 ccttcatggc tgacttgact gtattaggaa tgtcatgaag tttgagatcc aaaaagacac
    27181 tatgacccaa accttttaag taggacacaa tctcaggccc cgctgcgtaa taaagctcca
    27241 tccctacctt gagataaagg ctttcttctg ctgggaaaag agctaaaaat tccttgaccg
    27301 cctcaaaact aggaaaatca agagcaatga ttggacgatg ttctcgcata ggtttctcct
    27361 tttaccttta ctagtgagag agtctggcca acagaagcca cgaaaaaagg aacctgccaa
    27421 cagcaaggtt ccacgaaaaa tgggtagtct ccaccctttc accgtctaac cttagctgcc
    27481 tctctggact gctttaaagg ttttctatta ttctattatt tctactagca cttgtcaagt
    27541 aaaaacttag tcacgtatgt gttgactgct attgaacacc tcacaagact ctttccaaaa
    27601 gaatagttaa agactttcac ttaggacaga gaaaaagagt ttgcttgtta ccctttaatt
    27661 gaacaaatgg gaattctgtt ttattttgcg gatgcctatt catcttggca aaggggaagt
    27721 aatgagaatg cgaatggact tcttcgtgag tattttctta aaccgatttg gcaacaatta
    27781 ccgaaaaaat ccttaatggt gctttgctag cttattaatc accgtcccca aaaatacttg
    27841 gattacaaga caggttttga agcacttata gaggaaattt aaaaatgttg cattttttat
    27901 tgcaatttat cagttatctt atcacccaaa acttctgcaa ttagtatgag cactattgtt
    27961 atttttcttt tttcgtacac tcaaatcaaa atatagcaat aagactattc tgtagaattg
    28021 ctgtcaaaaa gatcagttca tttttccttc ccacttgtgt ttataatcat taaaataact
    28081 caattaagaa attttctttt tcctaatagt tatcgtaatt aaagttaata gaagaacaat
    28141 ccaaataagt agtgttagat taggaattag agttttattc catgaaaatc cctcccattt
    28201 tgtgaaaaac ttagtaaaca gtcccataaa actataatct gttatcttcg caactgtctt
    28261 atccaaacca gatagcatcg gtaagaaagc aactaaaatc atagcaggaa gactgataac
    28321 ctgagctact acttggctct tcgcggttaa acctatcaat aaatagaata aaatgatgga
    28381 taaagaggtt agaagaacga ttgtaatata attaaaagta tgtacaattg taactcctaa
    28441 aataagagga gtagttccca taatcacaaa agttagcaaa aaaggaagaa acatcgttga
    28501 taaaatgtat tcggatcctt taacaccact caacagaaga gtttgtaaat tgtacttttc
    28561 tttttcttca gacaagataa tagttatagg acttccaaca gccaaagcca aagaaaaagg
    28621 taaacacatc atcaaaagaa ctaatgcctg ttgatcgttg accttcccct gtgtttccat
    28681 aagatattta taaaaatatg tgaaagcaaa aggcactaaa acttgcaata aaatactctt
    28741 attggaaagg ataatttgac aacgcaacca taccaaagcc agaaaccgtt taagcattta
    28801 gctttcctcc tgttaatgtg ataaaaatat cttctaaagt aggctcacat gaatgaattg
    28861 aaaaaatatt ttccagatca gcctgagata cctgttctag tgatgtaaaa tcaaaagtta
    28921 tctgattccc attataatct gtaaccttaa tctttttatc tttattatat ctttgaatga
    28981 gttcagaagg agctccttgc tcaactaatt tccctttatt taataaggca acataatcac
    29041 ataaaagagt tgcttcattc atatcatgag tcgttagaaa aatcgttgtc cctgctgttt
    29101 tcaattctaa aattaactca tgaattgttc gagaagttgt gggatctaga cctgaggtcg
    29161 gttcatccag aaagagtaca gcgggtttgt tgataagagc tcgtgctaaa agcattcgtt
    29221 gcctcattcc agtggataat tttcctgcta ccatcttgcg actatcatat aatcctactc
    29281 gctttaacaa attatcaaca cgtgatttac taatattata aaatttacta taaaaaagaa
    29341 gattgttata cagagacatt ttctcataaa atccacttgt atcgctaacc aatccaattc
    29401 tctttaattc accgcttgtt aaattttgag atttttgtcc caaaataata gattgtcctt
    29461 tatcggcaag gaactgccca gtcagaatat taatcgttgt ggtctttcca gaaccagatg
    29521 gtcctaaaaa tctaaccttc tttaacagtg aagcttatat tatttaaagc tattttatca
    29581 ccaaaacttt ttgataaatg gctaacttca atcatactca ttgcacctcc tttatattct
    29641 acatttttac ttaacatcta tttacttatc tttatcaaat aaacgtctta aaaaaaacaa
    29701 taacattaag catataaccg ttagcaagat tgtttcaata ttattgataa tacgatacat
    29761 tctcaagcag tataaaataa ttatatatat gcaaatgctc attataccta tttttttaaa
    29821 catactaagc ctccttgcta aataataaag ttatataata actaagacac actataccta
    29881 acataataaa tatccactgg taactgaata aatgttctaa aattaacaag caaaaataaa
    29941 atctcaaacg atgaaaaaag ccatactata ttttccaatg atgtttgaat atttttattg
    30001 tagtaagcat aatatatagc aaaaataata cccaagaaca atactattaa ttgtgtttct
    30061 ataacagtga actgcccaat agcagataaa aaagctactc ctcctgataa taagcaaaaa
    30121 caaactgaac gaataaatgt tttcgctcta atattgttat ctttcacttt attatttttt
    30181 tacaaattgg acattctccg ttttccagaa catatttttc ttgacttaga gcatgatttc
    30241 tcatattata aacgtaagcg ttatctatta ggatttcatt ataacatccc agaaatattt
    30301 taattattaa attagtcatt atccctccca aaatagcagg catctctggt gtagtcggcc
    30361 actttgtctt atcagataaa gtgtacttat ttatatcttt gtttatattc cgacaaccaa
    30421 agcaagaacc gatggtaggg atatatatta tcagtaataa gatagcatcc attaaaccct
    30481 cctgatatgt aggatatctt atgcgataca gcaaattgat tgacaatttt tataatatca
    30541 atgggcgtat caattgcttt aacgataaaa tctatactcc catattccgc aacaattttt
    30601 tctaattctt ctactgaaga aactttaata gaaataggta ctacctgaac atctgaatta
    30661 tacttgtgta ttttttcaga aagaacatta atcttctcct taccaacatc cgactctgta
    30721 taaagaattt gcctatttaa atttgatggt tctattatat cgtaatcagc gacaataagt
    30781 ttcctcactc catacatact tagacttaga gatatataac atcctaaggc tcctgctcct
    30841 aatactaata ctgttttatt ctgtatttta ttatactctt cattataaaa taacgaatag
    30901 taacctttag ttctagaata tctactatca atatctatct catccgaaat taaaatttgt
    30961 tcatttaata gttcaaatgt tagtttactg cctaatactt cttctatctc taatagttcc
    31021 ttacaactat taaatagatc gttgataaat tcttgcgaaa tttgaggttc tatagctatt
    31081 tcccgcatac tccgaccacg caaatacatt ataccttctt ttttataagc aaaaacataa
    31141 ctatttacgt agaacatatt tcgtccttcc tctcatatat aatatagaaa gcagtataga
    31201 aacaaccacc cctcctatac tacgaacaat aatattaggt gtcaaaaact gtaatagttg
    31261 actcaaaggg aaataaataa taacaaatgc tattaaaagt tgaactatat attgaaaatt
    31321 caagttatta ttgttagaat tcaagtatct taaaataata ccactatcat actgaaaaaa
    31381 aggaattgaa ttaataaaaa tcatacctaa gttaatgata aaaaataaga gtccaagcaa
    31441 tttatacgat gtgaacaata aaacaagtaa acctgtaagt gataaaatcg aatttgaagc
    31501 aattcctgct aacataattt tcaaaaattg ttttttattt tttaagaatt gcaccccact
    31561 taaatctaca aaaaaaagcc aaattaaaca aaagtagcat tattccacaa tttgggatct
    31621 caatttgata attattagca attattgcat gactaaattc atgtatcgtt gcagacataa
    31681 taacaacaag caaccaaaat aaaagaatgt ttagcgttat tggaaagttt tggaaattag
    31741 tcaaaatatc cgccctataa atatacataa taaaacattg caaaataaga gccaatggga
    31801 aaataccaaa taggattttt tcaaaattct tattaaatct tttatagttt aatttttcag
    31861 ataatgttat attaaagtcc caagatattt taaaaatatt tatctttttt cgtgatttca
    31921 tagaatctat aagtcccatt ttactaagaa caatataaaa tcttaaataa tatttcttcc
    31981 ctactaacac taataagtcc gatatggtaa attcttgacc tattagttgc tctaaccatt
    32041 tttttcctgt ttcccaacta atacatgttt cttactagat ggtatatata gatgatactg
    32101 tccctcataa ggagtaggta atatcttaat cttatcaaca attctcataa caaacctaac
    32161 ctttaataaa taaaagaggg gctaagtaaa acatactcta gtccctcagt ccgcaatcaa
    32221 taaaataatg actaattcta ttaatctctt gctgcaagac taatacggaa aattcaaatg
    32281 actgtctaaa atgaaattga aaaagcttga tgttagtaaa tgaacaaact tcaacaacca
    32341 gcaagagcaa ggattgctaa accaaatccg atacctgttg caagtccagc tgaaaaatca
    32401 ctaactggta ctgaaatttc ttcaatttcc tcaaataaaa agttatcttg catgattatc
    32461 actccctatc tttttaacaa caggctattc caattaagag aactacccca gttccaagta
    32521 aaactccccc aaaaattcac catctgtagg ggctacgatt tcttcaattt cttcaaataa
    32581 gaatgcttca tctgacatat gtgttacctt cttcataaaa aattattttg taatcgatta
    32641 cattgcaaat gtaacataaa gaaaaacaga tgtcaaatat taaacgtaag aacatggtca
    32701 ctaaagaact ataagagaaa aggtaaacct agcgacgcga tgagcgctgg gtcgtttgat
    32761 ttcgattgct ctcttcctct tgttttttct gttcttcttc ctgttttttc tcggcttcct
    32821 tggcctcttg tttggctttt tcctcagcct ccataattaa tttatccgcc acagtgtaac
    32881 tgtaaattcc agcttccatg tcgaccacac tcggttctga caattgtggc ttaatcttac
    32941 tgtaatatgg cagtttctta ctcatttcag atagaggaac caagacttcg tccgaatcat
    33001 tcatggtcaa tcgaattaaa tcggatgtca ccttgcttgg ggctaattcc accttttgga
    33061 tagccgcctt gagttctggg ctaatttgag caagttctga gacaaaaacc ttgatttgtt
    33121 cactatcatt aaagagaact gataaataag tttctggtaa actgttcaga ctcacagaac
    33181 tagtctcaag ctgaccactg gaaagaatag gataatgatt ttcaccagaa atatagtagg
    33241 ccacaatatc atattccttg accttaatag tgaacttagt tggaaattga tagacaagtt
    33301 gagctgattc aacccaatag ttagacttaa tctgcttttc atattttgcc ttgtctagca
    33361 gaaggttaat cgtataatcc gaatcctgaa tgcctgaagc ctgtcgaata tcatcagctg
    33421 tagtttgcac cgttccctca acacgaatat ctttcatggt cgcataagga ctgagcaagt
    33481 aggcagagac aatcaataaa agcagacttg gaaataaaat cgtgaaggct cgcaagatat
    33541 ggataccagg aatctttgct ttggctggtt tttcctttgt agccttttta gaaagctttt
    33601 tatcctgttc ctccttctct ttagactctg gttcttcttt ctcttctttc tctttgtcag
    33661 cctctgagga tgctactttt tcttcagact cttccttagc tgattctgaa tcttcctggt
    33721 ctgtttcact ctcctggtcc tgtttgtcct ctgacttctc agattcttct cccattcgag
    33781 cttgtctttc cttttccttc tcctcagcta gagccgcctc ttcttcagcc ttctttttta
    33841 gatattcttg gtttcgtttc tgccattctg ataactcttt caattcttcg aggatttctt
    33901 tgtcctcatt tttcttatct tttgacattt actttcctta tgataaatct tttttcaaca
    33961 attgataaaa atctgctaga gatttcaatt ccttagaagc cttcatctta gcttggtaat
    34021 cttccttgtg acttagtaag tgagaaagct tctcttccaa actatccaag gtcaaatcgc
    34081 tttcttgaag gtcttctgca tagccttttt ttacaaagta agctgcattt tcaagctggt
    34141 caccacgact agcttcacga ccaagcggca caatgacatg caattttgct atcgccaaga
    34201 gctcaaaaat cgtattggca ccacctcgtg tcacaacaat atcagccaat tccatcaagg
    34261 gttgatagag atcggtcaca tagtcaacac gaaaaagatt ttggctcaac tcattcaggc
    34321 tagaatctcc agttagattg ataatattgt agcgctctgt tagttctttc ttatggtctg
    34381 tcaccaattg gttaaagaca cgagcacctg cagaaccgcc aacaaacaat acagtcggca
    34441 atttatgatt aaagtggctt tgaatatcca ccaattcatc tggttctgga tttttttgat
    34501 ctgaaacctt ggccactgct cccacatgct caaccttaga caaactcgaa gcttgctcaa
    34561 aggttgaata catcttagtc gcaaatttat aggcgatttt attggccaag cccatagaca
    34621 ggtcagattc gtgaataaag acaggcactc ctgacacacg cgcagcgata acaggcggta
    34681 ctgagacaaa gccccccttt gaaaaaaggg tctgtggacg aagtcgcaac atgataaaga
    34741 gcgattggac gattccccag caaactttga agacgtccag catattttgc caagagaaat
    34801 agcgacgcaa ttttccagtc gcaatagaat ggaaggtgac atccaaacct gacttaagga
    34861 tttcttggtg ttcgatacca cgcttgtccc cgatatagtg gacttcccaa ccatcttcga
    34921 tgaacttggg cattaacaaa agattgaggg taacgtgtcc aaccgtcccc ccacctgtaa
    34981 agacaatttt tttcatatta ttcttttaac tccgctactg tgtcgataaa gaggtcgcca
    35041 cgtacttcaa agttagcata catatcccag ctggcattgg caggactaag aagaaccaca
    35101 tctccttgag tcgcaagctc ataggccttg cgggtcgcat ctgcaatatc tgtcgcctcc
    35161 acataagcga caccagcctt gtctgctgcc cgtttgacac gttctgcaga ttgacccagg
    35221 atgaccatct tcttgagtcc agtaatgtct ggcaccaatt cgtcaaactc attgccacgg
    35281 tccaaaccac ctgcaatcaa gacgaccttg ctgttatcaa atcctgacaa ggctttttga
    35341 gtagccaaga tattagttga tttactgtcg ttatagaatt taacaccctt gatgtcatcc
    35401 acaaactgga gacggtgttt gacaccaccg aaggctgaaa gagtttcctt gatggtttga
    35461 ttgtccacac cacgaagctt ggctacagca atagtcgcaa gggcattttc cacattgtgg
    35521 ctacctggaa caccgatttc attcgctgcc atgactactt caccacggaa gtagagttga
    35581 ccatcttcca gataagctcc atcaaccttt tcaagtgttg aaaatggtac aacagtggct
    35641 tctgtcttgg aagtcaagtc ttttgccaag tcttgattaa agttcaagac aaggaaatca
    35701 gctgctgtca tcttgttctg gatattccac ttggctgcta catattccga aaatgaccca
    35761 tggtagtcga tatgagttgg catgaggttg gtaataaccg caatctctgg atggaattct
    35821 tgaacaccca tgagttggaa agaagaaagt tccataacaa gcgtgtcctt atctgatgct
    35881 atttgagcaa cctgactagc tggatagccg atattccctg ataaaagacc atgttgccca
    35941 gcagcagtca aaacttcccc aatcatagtc gttgtggttg tcttaccgtt cgatcctgtg
    36001 ataccaataa tcggtgcttc tgaaatcaaa taagccaatt ccacctcagt caagactgga
    36061 attcccttgg ccaaagcctt ttcaatcatg ggattgttgt aggggatacc tggatttttc
    36121 accataaggg caaactcttc atccaagagt tccaaaggat ggccacctgt aatgaccttg
    36181 atcccttctt ccagcaaact ttgggcagct ggattgtcct cgaaaggttt cccatcattt
    36241 actgtcacaa tggcacctag cttgtccaac aaacgagctg cagattcacc agacttggcc
    36301 aaacctaaaa caaggacttt cttattttta aattgatcta ttactttcat gtctcgaact
    36361 ccatttctac tcctactatt ttaccatttt tatggaaata aaaaagccac aaagtgtgtt
    36421 tgtgactctt tcttctaact gaatcttacc atatcatcta tgtgataaat cggtaactcg
    36481 aatgacctga tccacttgtt cccaaataag aggattgtgg gtcgcaataa taatggtccg
    36541 attcggattt tttaaagatt ctaggatgga aagtaattcc tcagagtttt tggggtctaa
    36601 ggaagtggtt ggttcatctg cgaggatcaa aggtggatcc tttaaaatta tcttcgctaa
    36661 tgcaacacgt tgtgcttctc ctcctgataa ctcaaatata ggttgcttca aatccaaata
    36721 agagaggttt acacagttta gagcttgttt catcaaagag attttctctt tttccttcaa
    36781 ctttttacca actaaaccca gattgagatt ctctttgacg gtttggcttt caattaagcc
    36841 aaaatcttga aataagtatc ccaagtaatc tctaaagaaa acagaaggct tgatgtcctt
    36901 aagagaagta ccatcataga tgatttgtcc tttgtcatat ggctctaatc gtccaatcat
    36961 attcaagaat gttgtcttac cacagccact tgtaccgatt aaggcataaa ttttcccacc
    37021 ttcaaaatga agatttgtat ctgaaaatag ctgacggctt ccaaattttt tagatatatt
    37081 ctttagttca atcatcctat tttcctttca taattgtcat agaaacacga gattctttct
    37141 gcgcttgacg gtaaagcgtc agaactgcac tagctagaaa gactaataaa gtgagcaagc
    37201 caatcaccaa gtctcgactg cttaaaataa agagactagc accaaataca aaactggcaa
    37261 attgactaac catatactga gcatgtgttt caaaaaatcg taaacctgaa attcgtttaa
    37321 tcaaaatatc tcggcggaat tgctcgaaat atagaagatt gacagaataa aatagtaata
    37381 aggaactagc tatccccaca atagctccta agattaaagt tgctgtttca gtttgaactt
    37441 cattataacg agttagataa acacttcttc cttctttaag ataggatact tgctcataaa
    37501 ttccagcttt cttcaagagt tctagcccac tctcatatcc tttgataaag agttgttttc
    37561 cagcattgat agaccaacta gataaggata taaaactatc acctgtagaa gtcggcgtga
    37621 ataccactaa aatcggatca gtcaaatact gagtagatac gggattctca ccgttattat
    37681 aaacaaaccg cttttctccc attgaaagat aactaacgtg cgctttcatc tcataatcca
    37741 aaggagcact tgcctcctca ccagattttc cataataact caatctttct tcaaaaactt
    37801 tcttaagttc tgcttctcga gagcgcaaat gttctgggag caagaggata aactcacctt
    37861 tttggagatg ggctaacttc tgtttggtct cagcatctac cacgaccttt tccttgtcca
    37921 aataactggg actaacatag agcgtattag catctggact ataggtatcc agtgtctctc
    37981 cctgttcatt ttttccttgt ggattggcaa aatggagcag attatccttt acataaagag
    38041 cttgttcttc ttcgattgct tccttggcaa aggcatacca cttgctctga ttttctgtat
    38101 cttttcctct atcacctaag ccaaaagaaa tttgataata gtctgctcta tcctgccatg
    38161 cttgttttga aatttcaagt tctttcaatc gttggtaaga catcaaacct gtcttaacag
    38221 cgtagcctac tgtaaagaca gcaaccaact gacacaatag ggttaaaatc atcaggcgtt
    38281 taaggggtaa tctcccctta ataacgggaa ctaatgcttt gtaactcaaa ctcattagat
    38341 aaagaagcat tagtaaaatt gaaatcgcca ataaaaacaa cagatagaaa ctaatcccaa
    38401 aaccataggt ggctaacaag ataggataaa acaaaccttg actaaaaaga acgactcccc
    38461 cacctaggaa ggaaaggagg gctgatagaa ggagccattt gatatcagta gataaagaat
    38521 gccccatgat ggataagaga gtctgaccag aaaagagttt tatacctgct gctctcattt
    38581 ccttaatccg agtgataatc actaaagcaa agaaagataa gccaaatatt gctaaactaa
    38641 ttaaaataag gggatttagt aatattcgaa aagcaagaaa atagggcggt atctttcggt
    38701 cagcacttgc tttataaccc aaatctccta atttatcggc aagcttttct ttcgtcaagg
    38761 agcctgacaa aaggagataa ctatttagcg gatcactacg ttcacgactt tcttggctag
    38821 cttcttggaa ttcttttggt aaagttccct gaccataagt tgcataagta aagtgagtcg
    38881 tcccatcctt actcggctct acaattcttc tagctattaa actctgttct gagtttgcaa
    38941 aattctccaa ttcctgttca aatacctcac gcgtcggttc ctgagtatct tttttgacac
    39001 gaagtaaaga aacggaatca tagcttgcat ataaatattg tggcgcacgt aagacaataa
    39061 tccaagcaag gaagaagctg agaaaaaaag ttgataataa tatgaatagt ttcttcatag
    39121 tagactcctt gtaaacaaaa ttccccctgt aatttcttac aaggggaacg atttaaatca
    39181 atgaacgatt agtcataatc acagtaaaat gctacttgtt ctccccattt agtccaaatc
    39241 catgcatagg aggtttttcc agcagaagct tctcctttat ctgaatgact attccatcta
    39301 cttacaagag aagaataatg atatttttta ccatgatagt aatttgaaaa agcccaacca
    39361 cctcctgaac cttctccata cgtccatact cctccatctg gatattgtac agcagctgat
    39421 gcagctccca ataatgtaaa acttgaaata agagctagag caagtaatct atgttttttc
    39481 gttttcattt tattttttct ttcaaaaaaa gcacaccttg agcaacaatg caacaaaata
    39541 aaccctcctc tctcttttgt tgaaaccgct ttcttatgtg ataaaaatat catttttatt
    39601 atttgttgtc aaggaaaaaa tcgaattttt tagatatttt actacattgc ctctatgaat
    39661 aatattatat agtagtttta ttttaaaata atatgcaacc agtactaacc aaatataaaa
    39721 tagatgccat taacgaattt tattcaagtt tttcccattc atactatcca agcaaaagag
    39781 atgatgttat agtacaaaac aattcaaact attgtaaaat tcctagcaaa aaagagagcc
    39841 aaaactctct tttttatctt cttttacttt ttttgactgg catgagtgta atgtctctaa
    39901 cactaaagta agctaggatc aacatggcta ttgctaggaa tatttctgtt ggtaattgaa
    39961 aaattttcag aaaagataga accaataaaa tcaagagtgc cactaaaata cataccatag
    40021 cgacgatatt gactgtccct ttaatgcttt ctggtgtcgc aaatacatag agtaggagca
    40081 gtaaaattcc taggactaaa tagaccatct ttctctcttt ctagctctta ttcagctgat
    40141 tttttcttct tgttagcttt ctcacgctct gctttgttaa ggatttgttt acgcaaacgg
    40201 atagactcag gcgttacttc catgtactca tcgtcgttca agaactcaag agactcttca
    40261 agtgtcaaga tacgaggcgt cttgataaca gctgtttggt ccttagtagc tgaacgaacg
    40321 ttggtcattt gttttgcctt cgtgatgtta actgtcaagt cattttcacg agagttttca
    40381 ccgatgatca ttccttcata aacctcagta cctgggttga caaagatcgt accacgttct
    40441 tcgatagaca tgattgagta agttgtagcc ttaccagcat cgatagaaac aagggcacca
    40501 cggtgacgtc caccaatttc ccctggaatc aatggcaagt attggtcgaa ggtatggttc
    40561 atgataccgt aaccacgagt cattgacaag aactcagttg agtatccaat caaaccacgc
    40621 gctggaacaa ggaagaccaa acgagtttga ccattaccag ttgaaatcat atccaacatt
    40681 tcacctttac gttcagaaag gctttggata acagaccctt ggtattcttc tggagtgtcg
    40741 atttgtacac gttcaaatgg ttcacattta acaccgtcga tttcttttac gataacttct
    40801 ggacgagata cttgaagttc atagccctca cgacgcattg tttcgataag gattgacaag
    40861 tgcaattctc cacgtcctga aacagtccat ttatctggtg aatcagttgg gtcaacacga
    40921 agggaaacgt ctgtttgcaa ttctgcctgc aagcgttctt ccaccttacg agaagttacc
    40981 catttacctt ctttaccagc aaatggtgag ttgttgacca agaaagtcat ttgaagagtt
    41041 ggctcatcga tgtgtaggat tggaagagct tctactgcat ctgtcggagt gatggtttca
    41101 ccgacaaaga tgtcttccat acctgaaacg gcaatcaagt cacccgcttt ggcttcttgg
    41161 atttcacgac gttccaaacc aaagaaaccg aagagttttg taacacggaa gtttttagtt
    41221 gtaccgtcaa gtttagaaag ggtaacttgg tccccaacct taactgtacc acggaagaca
    41281 cgaccgatac cgatacgtcc aacgaagtca ttgtagtcca aaagtgacac ttggaactgc
    41341 aaaggctcat ctgagttatc tactggagct gggatatggt cgataatcgt gtcaaagatt
    41401 ggtgccatag tcgcttcttg gtcagctgga tcatctgaca atgaagaagt tccgttgatc
    41461 gctgaagcat aaaccactgg gaaatcaagc tggtcgtcat ctgcaccaag ctcgatgaaa
    41521 agttccaaga cttcatccac tacttctgct ggacgagctg atggcttatc gattttgtta
    41581 acaaccacga ttgggacaag gtcttgttcc aaggcttttt tcaatacgaa acgagtttgt
    41641 ggcatggttc cttcataggc atctacgacc aagacaacac cgtcaaccat tttcatgata
    41701 cgctcaactt ctccaccaaa gtccgcgtgt cctggtgtgt ccataatgtt gatacgagtt
    41761 ccgttgtaag caacggcagt atttttagca aggatggtaa tcccacgctc tttttcgata
    41821 tcgtttgagt ccatagcacg ctctgccaat tcagtacgtg catcaagcgt ttctgattgt
    41881 ttcaataatt cgtcaaccag ggttgtttta ccgtggtcaa cgtgggcgat aatcgcaatg
    41941 ttacggatat cttctcttaa ttttgtcatg atttcctcta taatattcaa aatttatttt
    42001 ctaactgaac gattatacca taatttcaaa taaataacat aactcaagca agtgtaaatg
    42061 ttttcactcc gcttttcttt tcacgtcaag ccttttcaaa gcaagcgact tatgataaga
    42121 taggcacagt atgcgtttag ataatttatt agcccaagaa aaagttagcc gaaaggccat
    42181 gaagcaagca ctcctcagag gggaaattct agtcgatggt tgcccagccc gatccctagc
    42241 tcaaaatatc gatacaggac tacaagaact cctttttcag gatcgaatca ttcaaggcta
    42301 tgaacacacc tatcttatgc ttcataagcc tgctggtgtc gttacagcca acaaagacaa
    42361 ggaacttccg accgtcatgg acctgcttcc atctgacatc cagtctgaca agctctatgc
    42421 cgttggccga ctggaccgag atacaacggg actcctcctc ttgaccgata acggtccctt
    42481 gggctttcag ctcctccatc cccaatatca tgtcgataag acttaccaag tccaggttaa
    42541 tgaacttcta acacctgacc atatccaagc ctttcaaaag ggaattgtct ttttagatgg
    42601 tactgtctgt aaacccgcaa aactagagat tctatctgca agtccctccc tcagtcaagc
    42661 ctctatcacc atttcagaag gaaaatttca tcaaatcaag aaaatgttcc tctcggttgg
    42721 tgttaaggtg actagcctca aaagaatcca atttggggac ttcacattga acccagattt
    42781 agcagaaagt aactaccgcc ctttgaacca aaaagagtta caaatcatta aaaactattt
    42841 agagatgagt cgataaaaca aaaaaagctt taaaactaaa gcttttttct tttatttacc
    42901 gaaaaattaa ggcgattgct acaatccagt taactacaga aatcacaatt cctaagatat
    42961 taagaatctt ttctatttta tagtctaatt gtgactcttt ttggtatgaa atagccaaga
    43021 ccaatcctat gatacccaaa atcaagccta caattggaaa taacaaacca agaataatcg
    43081 acaagatacc cacaaaaagt ggatttttct tcttttcttt catgttctaa gaactcttta
    43141 aattttatac aaattaatta tactataaaa caatagcttc atcctatcat tcgactaatt
    43201 tggaaataag gttagctagt cttcactttc cctttccaag aatccaagcc ataagaaagg
    43261 atataaatct cagaaaaacc ttgttttttc aagtaaagag ctgcatttgt aactcgttgc
    43321 gcacgttggt tctcgtagag aaggacaggt ttatctttac gaagggctgc aagactagtt
    43381 ttcaactgac ttgaaggaat attgcgtgca ccaaggatat gttttctgtg gaattctgct
    43441 gggtcgcgca aatcaatcaa ttgacccgta cgaatcaagg cttcaaactc ctcattgtcc
    43501 acaattttag ccgcacgacg aatacgaaga tagttaaagc ccatccacgc caacattgct
    43561 agtataagtg cccacaaaat ccaagtaacc attagttctt ttctccattt ttctcaatat
    43621 aatccaattc taccttgtgc tctctgcgaa gaactgcttc tgcctctaga tagtctaatt
    43681 tatccatcaa ccctgcatcg taaatccgag atagttccaa cttcatcagt tcaatatcat
    43741 ataagcgttt tcccatgtaa acaataatac caaatcgttt gaggaattgc tgcacatcat
    43801 agaatgtttt cataagactc attctagcaa aattttgtgt ttttttcaag aagagactca
    43861 cacaatgctc cttattttcc tatcttcttt ggcgattcta aggcaagtgt ggtacaataa
    43921 aaacatgaga attcaacaat tacattatat tatcaaaatc gtcgaaactg gctctatgaa
    43981 tgaggcagcc aagcaactct ttatcactca gccaagtctt tccaatgctg tgagagattt
    44041 ggaaaatgaa atgggcattg agatctttat ccgcaatccc aagggaatca ccttgacccg
    44101 tgatgggatg gagtttctct cttatgcccg tcaggttgtc gagcaaactc agcttctgga
    44161 ggaacgctat aaaaatcctg tcgcccaccg cgaactcttt agcgtttcgt ctcaacacta
    44221 tgcctttgtg gtcaatgcct ttgtctcttt gctcaagaaa agcgatatgg agaaatacga
    44281 gcttttcctt cgtgaaactc ggacttggga gattatcgac gacgtcaaga acttccgcag
    44341 tgaggtcggg gtcctcttct taaacagtta caaccgtgat gttttaacca agatgctgga
    44401 tgacaatcac ctactagccc accatctctt cacagcgcaa ccgcatatct ttgtcagcaa
    44461 gaccaaccct ctggcaaaga aagacaaggt gaaactgtct gatttggaga atttccctta
    44521 cctcagctat gaccaaggga cgcacaactc cttctacttt tcagaagaga ttctttctca
    44581 agaacaccac aagaaatcca ttgtggtcag tgaccgtgcc accctcttta atctcttgat
    44641 tggtttggat ggttatacca ttgcgacagg gattttgaac agcaacctaa acggagacaa
    44701 tatcgtttct atcccactgg atattgatga cccgattgag ctggtctata tccagcatga
    44761 gaaaaccagc ctatctaaga tgggcgaacg ctttatcgac tatctactag aagaagttca
    44821 gtttgatagt tgagaaatga taagaaccaa tatgtaggct agcaacaacc tgcacattgg
    44881 ttctttttac ttataattaa aagtttcccc tgccaactta tcagctagct tgggaaagag
    44941 agtataaaac ttatgggcta ggttcaacaa aatcgggaga ttgagttctc gtttattttt
    45001 tcctataatc ttgacaatct ttttagccac tgcatctgcc tctaagagga agcggtcaac
    45061 cgatttaaga taagttccat ctgggtcagc ttggtcaaaa aatcctgttc ggattggacc
    45121 tggattgact gttgtcacat agactccata gggcataagt tcgagtcgca gagcatttga
    45181 aaaaccaata gccgcaaact tggtcgctga gtaaagacta gacttgccag tagctattag
    45241 acctgccatg ctgacgatgt tgatgatatg ccctttgctg ctttccttca tacgagccgc
    45301 aaggtgacga gacagattca tcagggcaaa ggtattgacc tcaaacatct ggtgaatatc
    45361 tttatcagca atctggtcaa atccctcaaa aatcccgtaa ccagcgttgt taatcaagac
    45421 atcaatcttg ccatagcgga gataaagatc agttaccaga gcttctaggg ctgaatcgtc
    45481 ggtaatatca atttcaatca attctgcatg ggaataattt ccgtagagtt gggctaattt
    45541 ttccttattt ctaccaagca agatgagttg gtcattgggc aggagtttga ccatttcttg
    45601 agctagacca ccgctagctc cggtaatgag aatagtaggc atacttatcc tttctgtgac
    45661 tgctagattt ccacttcttc caagtctttg accacatgga cattttcaaa aattgtggca
    45721 gcgtccttct tgagtttgct tatatctttt gagaggaaac gggcactgat atggttgagt
    45781 aggaggcgtt tggcacctgc ttctaccgct acttgtgcag cttgcatatt agttgagtga
    45841 ccatggttac gagcaatttt ttcatcaccc ttgccataag tggactcatg aactaggaca
    45901 tctgcattga cagccagacg cacactggca tccgtttttc gagtgtctcc taaaatagtg
    45961 ataatcttac ctggacgtgg cgctgagata tagtctgctg ccttgatttc agttccgtct
    46021 tccaaaacaa gatcctggcc gtttttgatt ttaccaaaaa gcgggccgaa cggaacacca
    46081 gcagccttga gtttttcagc atccagcgtc ccttctagat ccttttgcat gacacgatag
    46141 ccaacacaga aaatagtgtg gtccagctcc tctgcataca cagtgaattt atcggtttca
    46201 agaattttac ccagagaatc ttggtcaaac tcatggaaat gaatgcggta gggcagacga
    46261 gaacctgaca cacgaaggct ggttaagaca aatgacttga ttccttgagg tccgtagatt
    46321 tccaaatctg tctgctcttc attggcctga aaggcacggc tagaaaggaa acctggcaaa
    46381 ccaaaaatgt ggtctccatg cagatgagta ataaagattt tgctgacctt acgtggtcga
    46441 attgtggttt ccagaatgcg attttgcgta ccttctccac agtcaaagag ccaaacttcg
    46501 ttaatctcgt ccaaaagttt cagggcgaga cttgaaacgt tgcgggcttt agagggctga
    46561 ccagcccccg ttcctaaaaa ttgaatatcc attcgatact ttctaattaa tcaatatata
    46621 acatggctgt gcggttttcc gatcggaaat agcgtttgcc agaaaaagca gcagcttctt
    46681 gcaataaatc ctcttggctg tagcctttga gacgttttcg accatcagcc aatctttcca
    46741 aatcagtcaa agctgtgaga ctttctaggc tgacaacttc ctcgtccttg acaggcttca
    46801 tgtaaatctt accagactct tcaaagacta attgatggga gaaaatttgc gcaatttcaa
    46861 agagcaagtc atccgagatt ttctcctcat tttcagagaa aatccgacca aagccgtcac
    46921 tctcataaca aaaaccaaag gatttaccag acagattaag ccgaataaaa ggcttatttt
    46981 ctagggtgaa acttggctca gtattgtaaa gattcagttc ctgactgagt tctgcaaaat
    47041 aatccgtcgc agcctgagga ctttttttct gatagagttc tgcaaagtag gcattaacaa
    47101 cacttggcgg aggtgtaata agtgttaact gctcctgctc tgttttacca gctagaagct
    47161 gatccagata gaccttgtcc agacttgtat aacctccata ctttagagcc aaagttttaa
    47221 tatcagtcat aaaattcttc taacctccat ttatttttct cggaaatgta gcctgtaatc
    47281 acttcgccgt cttcctgata atcacgttct tccagaattg caacactctc taaatcatga
    47341 atcttgtagg actttgaaaa aggcactcgc agggtaaatg cttcaaaaat ttccttaatc
    47401 ttatctagca ataatgcttg caagttttca cgactgtcct cagacttggc agaaatgagg
    47461 gtatatggcg tttgggtagg cgtgaaatcc tccaccaaat ccgctttatt ataaagcgtc
    47521 aagtgaggaa tatcttccat gtccaggtct ttcatgatgg agagaaccgt tttttcatgc
    47581 tcctcgtggt aaggattgct agcatcgata acatgaacca gaaggtccac atgcttgctt
    47641 tcttccaagg ttgacttgaa actggacacc aactctgtcg gcaaatcttg gataaagcca
    47701 acagtatctg tcaaagttac ttggagattg cctcccagat gaatactctt ggttgtcgca
    47761 tccagagtcg caaagagctc atctgcttca tactgggtct tactggtcaa gatgttcatg
    47821 atagttgatt tcccagcatt agtataacca atcaaaccaa tcttaaaagt gctagactcc
    47881 aaacgttttt ctctgacagt cgcacgattt ttctcaacca ccttaagctg gcgctcgata
    47941 tccgtgattt gattgcgaac gctacgacgg ttcagctcca gttggctttc accaggacca
    48001 cgggaaccaa ttccccctgc ctgacggctg agcataatcc cctgaccaac caagcgaggc
    48061 aagaggtatt tgagttgggc taggtggact tggagcttcc cttcatggct tcgagcccgc
    48121 atggcaaaga tatccaaaat caactgcata cggtcaatga ccttaacacc gagaacttcc
    48181 tctagattga cattctgcct tggggtcaga cggttgttga cgatgacagt agtgatttct
    48241 tctgcatcca ccataagcgc aatctcttcc aacttaccag agccgacgaa ggtcttggaa
    48301 tcatattttt cacgtttttg tctgtagcta tctacaacga ctgcccctgc cgttttcgct
    48361 aaactagcca attcttccat ggagaggtca aaactgtcca taccctgcaa ttccacacca
    48421 atcagcagga ctcgctcctc ttttttctcc gtttcaatca tctaaaaact cctctatctg
    48481 gcttaaaatg cggtcttgta caccagattc tccaatctga taaaaggtga cctgcatgcg
    48541 attacggaac caggtcagct gacgcttggc aaaacgacgg gtcgcctgtt taagactctc
    48601 acgagcttcc tccaaggtct gctctccacg gaaataagga aagagttcct tatagccaat
    48661 tcctttagca gcctgtacat taggggaatg gtcaaacagc cacttggcct catccaaaag
    48721 cccagcctca aacatcaaat ccactcggtg gttgatacgc tcataaagtt gactacgttc
    48781 atcatccaag cagataatca gcggttcata caaaatctct tgattttcca aatcctgacc
    48841 aaaatgggca atttctaagg cacgcatagc acgacgacga ttaaactggg gaatctcaag
    48901 gcctgcttgc tccaccaaat gggctaattc ctcatctgaa tatggctcca aactagctcg
    48961 ataagctaaa atctcctcat gaggagtctc cccacctagg tggtaacctt ctagcaagct
    49021 ctggatataa agtccagtcc caccggcgat aatggctagc ttgccacggc tgtgaatatc
    49081 ctcaatagtc atcttagctt ctgaaacaaa atcaaaagcc gagtaagact cagttatctc
    49141 tctaacatcg attaaatgat gaggaacagc tgcctgctct tctggactag ccttggccgt
    49201 cccaatatca agtcctcgat agacttgctg gctatctcca ctaaccactt cgccattaaa
    49261 gcactttgca acttcaatag ctagagccgt ctttccaaca gcagtcggtc caacaatcac
    49321 aattattttt gttttcatct tttttccttg aaaaattccc attttttcgt tactattatt
    49381 ataacacaaa aaggtcagtc agaaaaatgt gacctcttga ggaggctggc tgattgagaa
    49441 tataaaggag gaagactcat ggctaaagga ttcgctaaag gtcttgtaac aggtgtcgca
    49501 ggaactgtcg ctgccgttgc aggtgcagta tacgcattta aaaagaaagt aatcgaacca
    49561 gaagagcaaa aagcagcttt catcgaagaa aaccgtaaaa aagcagctcg tcgccgcgta
    49621 tcacgttaag aaacaaaaga agttgggatt attctcaact tcttttttct attcttttaa
    49681 atagctaggt caaacttcaa ctgtggctta acagggtcat aatccaccaa ctcaaaatct
    49741 tctgctttga tatcaaagaa attagtccca tcaggaacat ttaaaaccaa gcgtggttgg
    49801 cagtttgacg gctcccgacg gagcaattcc tgagcttgtt caaattgatt atcatagata
    49861 tggaggttgt tgatgaagta gaagaacttc ccaaccttcc agccaaaatg tttagcaatc
    49921 atcatctgca aagccacata ctgcatagcg ttgatgtggt gggccaccag catatcattg
    49981 gagcgctggg tcaaggtcgc atccagatag atttccccat caacacgccg aacatcaaac
    50041 atggtctgaa aggcgcacgg gagcagccca tctgtttctt cgaaagcttg gtaatcccag
    50101 agagaaataa tattgcggcg gttccaagga ttggtttcca actgtttgag aagcttattg
    50161 ataatgtcgt gtttcttaac aacggcacca tagcgctcac caatggttcc cgtgtctcca
    50221 acttcccagt cattccagta gtgaacattg tacttgtcat taagcacttc taagctattt
    50281 gactggtctt ggtaaatcca gagaacttct ttgatggcgg atttgattgc aatgggacgc
    50341 aaggttatga taggaaattc tcctttagat aagtcgtact cggaaaaggc accagttaca
    50401 tacttggaat tagcaacagt cccatccttg tacttaggac gagcctgctc tgagaaaaca
    50461 ccttccttta gaatgcgttc aatattctct ttaaaaatcg tatctgcttt tgtcatttac
    50521 tctcacctca ttcattgtcc taactagtat agcataaaaa ataaaagagg aacattacta
    50581 actctaggtt agcattttcc tctctcatta tcttattgca atacaagtga tgctgctccg
    50641 ataactccag cgtcatttcc tagagttgca agagctaatt tagtagatgt gcgtacttgt
    50701 gggaaagtat tttcgtcata gactttttga acaccttgta gaaggaattc tcccgcagct
    50761 gacacaccac caccgatgac gattgttgat gggtttagga ttgaaccaat gttagcacaa
    50821 gcgattccca agtaacgtga gaagttacgg taaacaatca aagcaaggtc gtctccttct
    50881 tttgcgagat caaagacagt cttagcagtt acttcttctc cgttatcaat caagcgtttc
    50941 aaggctgcat cgccttcgta ttcatcggca tagcgacgag tcaagttgac aattcctgtt
    51001 gcagaagcga ctgtctcaag acagcctttc ttaccgcaag tacatgagat tggctggtca
    51061 aagtcaacag tgatgtgacc caactcacct gctgcaccag caacaccgtg aagcaatttg
    51121 ccttctgcga cgataccgcc accaacacca gtaccgagtg tcataaagac aacatctggt
    51181 tggttatcac cagcacccat ccagcgctca ccaagagctg ctacgttggc atcattatcg
    51241 atgaaaaatg gaatgcccaa agctttttca atcttttgtt tgattggttg aagggttttc
    51301 cagttcaagt tgtaggcacc gataacagtc cctttgtcac ggtcaaccac acctggtgat
    51361 cccattccaa tgccttggaa gtccgctgct gccaatccaa gcaagtccaa acgatgttga
    51421 atagactcaa tcatatcatc aacgatatga cttccctcat ccaaaatgtt ggtcttgatt
    51481 gaccattttc cttggatttc tcctgctgtt gttaagattg caaatttgat agaagttcca
    51541 ccaaggtcaa tcccaataat cttttgactc attatattct cctttttcat tgtgtagtaa
    51601 ttgaaaatgc ttacagtact agtatatcaa aatccattca cttatgcaaa ggtttgcgta
    51661 aatgaattat aaggaatttt ttcgcctacc agtatctgtt aaccatctaa atgatcaatg
    51721 gcatattgag ctgcatcatt tgaaaattta tcaaaatcag aagttaattg tctatacata
    51781 cgtttttttg acatgtggaa taacgaatta taactttttg cctttcctaa agcagcagaa
    51841 tattcactat tgctatcatt actagaagaa gctgtacttg cttgaccttc cttccaaact
    51901 ccgtcagcgc caacataata acgtccacca tcaacccatt cattgacagc cattttacca
    51961 tccgatttta gatagtaatt tccttgccat gtactataag cataagaacc atctgatgtc
    52021 aaataatacc aagcttgata ggtggcatca taaacccatt cacctttagc cattttacca
    52081 tctgatttca aatagtagtt tccttgccat gcattgcgag catatgaacc atctgatttc
    52141 aagtaatacc atgcttggta agaagaatca taaacccact caccttgtgc cattttaccg
    52201 tttgatttaa ggtaataagc tccttgccat gcattttttg cataagaacc atctgatttc
    52261 aaataatacc aagcttgata agaagagtca taaatccatt cactctgtgc cattttgcca
    52321 tcagctttca ggtaatagtt tccctgccat gcatttttca ctagatttcc atttccatca
    52381 aaatagtacc aagaaccgtc ctgcttaacc caaccacttg ctgtggatga agttgtatca
    52441 gtttgagttg tagccgcttg ttttgcttta aaagcaccct taggagcatt tttcaattcg
    52501 caagccacac catcatgatc gcggtctaac ttggcagaat aaccaggttc tccctcatga
    52561 agatccgaat atccattagc ccaagcttcc ttacagctcg aaaaatggat gttttcttcc
    52621 gccaaaactg gttgtgaaaa caaggctaaa attggcaacg tcaccagact catttttaaa
    52681 aatagacgtt tattcatttc tttctcccat aattatgata tcgatttcaa tattatttta
    52741 tcaaacttat ttcagcaatt caaggaaact tctggtcttt tctacaaact cctttggttt
    52801 tgccttattc aagacatgag ggccatcagg aatgatctga aactgcgaat ctgttaacag
    52861 tctatggaga gctttcatag aactaagatt cggtttatct ttgctgccac aaattagtaa
    52921 ggttggatag gagcaagtcc ctgctatatc cgttaaatca agtgtcttca attcctcaga
    52981 aactccgacc ataagagtct tgtctgctcc ctgtttttca aatactcttt tgggaagtag
    53041 tttaaaaatc agcaactgaa gataaaatag gatattccct gctaatttaa gcgggcatcc
    53101 tgacagaatc aaagctcgaa gatttggtaa atcgtaactg gaaagttcta gtgtcagggc
    53161 agcacctaag gacaatccaa tcaaaacaaa aggttctgtc tcttgagcta ggtgctgata
    53221 aactcgctct ttagcttgtt gatagttact aactccagaa ggaaataact cgatagcctc
    53281 agaaggataa tctgtcagta gattccgaac ttctttccaa gactctgctg actgccctaa
    53341 cccatgcaaa aatatcaatt tcatctagtt ctcctcaagg cttagttcat acaagcctct
    53401 cactgcatta cagccgtaaa tagcttctgc ttgggttaaa tctgccaagg tcaagacttt
    53461 ctcttctacc tgtcctgttt ctagcaaata ctgacggtaa attcctggta agattccaag
    53521 tcggataggc ggtgtgtaga gttttccagc gattttcaga accaaatttc ctatagaggt
    53581 ttcaagcagt tctcctgact tattgtggta aatcttctct tgttctccta ggctcaaatg
    53641 cggtcggtga gtggttttaa agtaggtaaa ggattgattc aaagcagctt cctgaaggca
    53701 gacttgggcc tgacaaaagc ttgtactgag aggggttaat acttgacgat tgacttctat
    53761 ctctccagat ttgctaaggc tgattcgcaa gcggtaatct cgattagctt cacaatcctg
    53821 acactcttcc tcaatcttgt gtcccaagtc ttctgcatca aaaggaaaag caaaataacg
    53881 actagctttt ctcagtcttt ccagatgttg atcttcaaac agcaggttct tctggctgat
    53941 ttcccctgtc gtaatcagtt ggaagcgagc ttgtttacga taaagaactg ctgccttttg
    54001 atgaacctct cggtattcag attcccatgt gctatcccaa gtaatccctc cgccaactcc
    54061 ataaatggct tgacctttgt gaagttgaat ggtacgaatg gccacattaa aaatccgtcg
    54121 tccatttgga agcaagagac caatcgttcc acagtagact ccacgcggtt gaggctccaa
    54181 gtccttgata atctccattg tcgcaatttt cggtgcaccc gttatggaac cacaaggaaa
    54241 gagtgagcgg aagatttcaa caaggtccac atcctctcgc aactgactct tgatggtcga
    54301 agtcatctgc caaacagttg aatactgctc tacctgacac agacgctcca cgtgctcgct
    54361 cccaacttca gaaatacggt tcatatcatt gcgcaagagg tccacaatca tcatattttc
    54421 agagcgattt ttgggatcct gttccaacca actggcctgt tcaagatctt cttggtcagt
    54481 taccccacgc tgagtcgtcc ccttcattgg tcgtgttgtc aactcgcgat cattttgctc
    54541 aaaaaagagc tctgggctca tggaaatcac tgccatctcg tcatgttcca cataggcatt
    54601 gtagcccgcc tcctgctcta ccaccatacg attgtagatg gcaaaaggat tggcacttaa
    54661 cttttgcttg agttggacgg tgtagttgac ctgataggtg tctccctgcc tcaagtgatg
    54721 gtgtatctgg gcaatggcct tttcatagtc tgctgcagac gtcacttcct gccaatttga
    54781 gggcaaatca atatcctcat aagtcagagg aataggggaa gtttctacgc tatcatgaac
    54841 agtaaagtaa agcaggtact ctcccagtag gggatccttg tgaactgcta atttttcctc
    54901 aaaagcaggt gcagcctcgt agctgacata ccccaccaca taataacctt gctcttggta
    54961 gctttccact tgtgccagca aatctgccac ttcttctaca tttctcgttt tcaactcttt
    55021 aataggctgg gcaaaggtat atctctcccc taaagtccta aaatcaatca ctgtttttct
    55081 atgcatacct taagtatagc ataaaaaggc agatacagac aaagctgatc taccttttta
    55141 cgattttatt cattctatgc ttgtggtgca gtaaatagat caccagagaa accgtctgtg
    55201 tttttaagga gagctttaaa gactttcgat ttcaagacaa ctgtatttcg gtatttgtct
    55261 ttaatactac tatcgtttag ttccgttaaa tctttagtaa cagcctcatc aaacatagtc
    55321 ttcaactgtt cataggttga aatttgagtg ccattaattt caattggtgc aaaacctttt
    55381 ttagattttg taagaacttc cccataccat tgcttcttcc aatcttcaag gtttgaaaat
    55441 tggttattag aaactttctt aataatgaaa tcatcaccta atagaccgtt attttcttta
    55501 ttggctgcac cttgatgttt gcttgaaaca tagtcaatga acccatgttc atatccatag
    55561 taaccccaca tacggaaggc gttatgtttg aaggatagag aaccaggggc accttgactc
    55621 gtattaccgc cataaatacc agccatcata ttaacattga catatgccgt accaaagtcc
    55681 tctgggtgga agaccttatt acctggattt ccgtgaatgg tcatgaaatt attatttacc
    55741 aagtcatcga tggtttcaag gttagttgtt ttctcagcgt ctatcaaatc acgcactttg
    55801 tcccattggt gaggaccact tagtttattt ctgtccattg gtcgacgtgt ttcgcgatca
    55861 attttcttga accacttact attgtcacct ttaaccttag gaagaacagc ctcagcttct
    55921 gcataatcga gcatcatcat agcttcattg tagttcttca tgtaatggtc gatttggtca
    55981 cgtgtttgaa gtttggtagg atctggatta taccattggt ttccatcatt tgaacgttca
    56041 aatgccatat ttaatccaag tgcgccatat tcaccttgat gtccatgttc tgctggagtt
    56101 tgtaacatac cttgagcaaa tgcttcaaga tctgtaccct gtcgatgtct atgacctccc
    56161 agatatgcca ttcggtcatt tacgtgggta gtctcatgtg taaaggcaga tgtgccatat
    56221 tcacttatta aatccgacat aacaaaatat acagcatcca taggctgtgg atcagcaaag
    56281 atgtaagcat acgctccata cccatactta taatcatgat acttatcaat acgtccaaag
    56341 aattcacgaa taggtgcata atccggttta tcttttcgat gaccaaatct atcaggccaa
    56401 ccaccgggtg caccatgatt atcccataca ggagttggaa ctacattttg actcttaaga
    56461 agtttatcgc ggacattatc agtggcaagg cgtgaccaaa aatctaagta attaacttgc
    56521 tctttagcac gtttattgat ttcactcttg aacgattcac gtttttcttc tgtatcttta
    56581 ccatactttt caaacgaact aaatgagata gtattatatg ttgaaatcat aaataaatgt
    56641 gcatctttca agttcagaag cgataaaatc atgcgtccat gttgtccgtt attaagtcct
    56701 tcatatagac gatatttttt attagcaaat gcagggttag ttgacggttg ttcaactaca
    56761 taagcattat tttcaatagc tttcttaaac caaacattta tgtctgtttc atttgtgaat
    56821 agtttcatat tgtaggtcaa gaagtcatgt aagtttccag aaagagtatt tttcgccacc
    56881 acttcacgga aggactcctg tgtacgactt cccttaatat agtcctcttt tgaaccaatt
    56941 tctattaatc gatctaaaac acttacattc ttaccataaa aatctggttt gaatagcatt
    57001 aattctttaa tattgaagtt atcaaatttc acaccgtaat aacgatttag gtatgttaat
    57061 cctaacagga cagcagcttt gttatcttca attttcttaa tcaaggcacg ttttgcagct
    57121 tcatctgtat tcagttgatg atcttcattt tcaactaatt ttgtcacaaa tgtattaaga
    57181 tgatctttta cttctttaaa gctttcttct aagtaaagat tcttaattgc attaactctg
    57241 ttatccccag ttcttcctaa tcgttgataa attggatcag attgtaattc aattggactt
    57301 aaaatacctt caatagcact aattaaatct gcacgatctt taacaaccat atttggtgta
    57361 tagacgactt caccaagctc tgcgacactg tattctttta cttgcttaac ttgagagtct
    57421 ttaggagaaa tcgtaaagat atcttttgtc ttatctgcgt aatgaaccat aatatggtca
    57481 gcatctgtaa ggtctgtaat aaagtcatta cctttcattg cagtcacaga caatacttct
    57541 ttattcatta atggactatc agttgtaagc ttgttccctt gattcacaat ccattctttg
    57601 ttgtagaacg gttggagttt ttcaacatta cgataaacaa gctcacgatt tgcattataa
    57661 tcttgaattg ttttgtattc ttcatcacgt aatatacggc gattcaactt atcaaccaaa
    57721 tgctcagtta cttcaaatgt atcagcagtg atacccatat ccttaatttt cttatcagct
    57781 tctacctgtg aaatttcttt aattttagac gattgtttat gggttttatc tccagaactc
    57841 acaccgataa ctgttgcatt attaggttta atccaattgc ttacaaattc atcatccata
    57901 tcattagaac caaagaaaat atcaccacgc ttaacattca ctaagctgat attgttatca
    57961 atggttcccc aaggccagtc tttaccaatt aaaccgccta catcacctct agcaacatca
    58021 atagtacctt tggctacaga atttcttaca ttagaccaag caccaacatc tcttggatta
    58081 aaatcatgag ctaaatgtcc tactatagca cctgcacgag tatttaaacc tttaagttca
    58141 acatctgcat aagctttatt taaattgcct cgataaatct cagatgcaat cccagccaag
    58201 ttccaccctt tatcaccaac agattgaact tttccgataa aagcaacatt agtcataata
    58261 cctgcatcat ctaatttatc caaaataccc gcaacattgt tattaccaac gatagtaccc
    58321 gttactttaa tattttcaac agttgcattt ttcactgttt gagctaatga agctaattga
    58381 tttgcccaag gcatattaat attaacgtta attaaattaa tatttttgat agaaccccct
    58441 tcaactctat caaataatgg acgagcagtg ttatgaatgg agaaatgctt accatcaaca
    58501 cttgttaagt gacctgtaaa tttacctgtt acatatgatt tacttggtgt aggtacattt
    58561 gttgcattta aatccgatcc taatttaaac tcaccgttag gatttttctg catagcatct
    58621 actaaatctt tgaagttata gtaaacgtta ttttgcgatg ctttgggttt ctctatgtaa
    58681 taagtgtatg tttgactcaa actattattt gaatcacgtt ggattaaatc aggagctgaa
    58741 gcagtaactt taaataagga tgtctcctcc tcagttactt cctctatatt agtaatggca
    58801 agccttgtta ctttattatg attagtggta atttttagat aatatgacgt tagattttct
    58861 ggaacagttt ctagaaggct actatctgtt tcatttccat tctcatccac tttcatcaat
    58921 cttgtttctt taatatcttt aatctcaact tttttaaggt ctaactgaac ttctttatct
    58981 tctaatattt cagtttcttc accgttacct cgatcataga ccatggttgt ggatagtgta
    59041 taaccttgat aatatttcaa gttgtctaaa gtagcttgta agttattttc ttctaccgtt
    59101 acttctttaa caactgttcc agtattatct tttagagcta ctttaatcga tttaatttct
    59161 actccagctg gtttagtcaa tgtataacta gctgtcgcac tcttcttcaa gacatcttta
    59221 tctgttttag cccattccaa ggttggtttc tctaactctt ttgtgccatt cttaataatt
    59281 ttgtcttgag gtttttcaat cactgtttct gtgatagtag gagcgtcact tgttttttct
    59341 ccgcgaattg ttttataggt ttcagtaatt tgtttcttat cgtttacacc ttcttgagtt
    59401 acttgtcttg ttccgcgttt taaagtgtca tcttcttgtt cttttgtttc aaaaggaatg
    59461 atttcttctc ttgtctcaac cgttgtccct tcaattggtt ttgtaccacg gattacctgt
    59521 tgatttacag gctccttggt gacttccgta ctggttgaaa gaacttggtc agttttaacc
    59581 cctcctattg ttttataggt tgtttttgta acttgacttc ctttttcacc atttcgtagg
    59641 acagtttctt cgtccgtgta cttggttggg tcctcagtcg tttcagtttt atagtcaagt
    59701 tctgtagttg attcttcaac gagtgttcct tcagtcacct tatactcagg taattgttct
    59761 ggaacaagag cctcacccac gtaatcttct tcttgcgtcc ccttagctgt tttagtctcc
    59821 tcttttggtt ctacagtttc ttcagccttg gtatctggag ttgactcttc ttgtttcggt
    59881 gtctcttccg ctcccctatc ttctttagga ttgtcttctt gtgatgattc ttttggtgta
    59941 cttggttgct cagcttgtgt aggttgcacg ggttgttctg ggacttttgc ttgttctact
    60001 ggtggttcaa cttttgattc ctcagctggt ttgtctgatg gttgactttc tggcttaact
    60061 gctacttttt cctctgattt tgactcaact tctccaccta cttcttcaac tggagctggt
    60121 tctgctgaat cttctttccc ctcttctact ttaggaaggg tgtcgtcagt aggttttacc
    60181 tccgattttg gttcttcctt tggactttct tctgttctag gtgcttcttc ttttggagtt
    60241 tcctctgtct ctactacttg gttttctgtc ctagcttgct cctgatttgt tgttgattga
    60301 ggagtctcaa cttcgactac agtcacctct ccaggttttg ctgaggtttc ttctaaaaca
    60361 gtgtccaagc caagcgtttt gaggatgtca cctgatagat aaccaacata gcgatagcca
    60421 tccatttcaa caacaccctc tcgactagcc agcgctaagg tcgcaactgg gtctacagcc
    60481 cctgcactag gaagaactac caatcccata gctccaacta gaaagacgct agcaattttc
    60541 tttctcttgt agattaaaag caagctccca acagtcagca aaccaaaagc tgtcaaaaca
    60601 gatgcttctg tccctgtttg aggcaactga tctttttgat acaccaaacc atatacaact
    60661 tcattcctgt caggctttcc tgtctgaatt aaatctttag cttcttgtga aataatctct
    60721 ttatttacat agtgataggt agctgcgtcc actacagaag gagccatcaa aaggcttcca
    60781 agaaatacag agcctacaac tcccttaatc ttacgaattg aaaaacggtc ttttttaaac
    60841 actttcatct cctttattca ttctcaagac tttctaatag catcttgcgg atagtgcgca
    60901 cgcgcacctc cgattaattt tggacgacta gccagtgccg ttacatgggc atgaccaatc
    60961 tctctcaaaa tagggcgaat cggaacctga acatgcttga catgcatgcc aattgcagtg
    61021 tctccgatat ccaatccagc atgagccttg ataaattcaa cctcaactgg atcctgcata
    61081 aacttaaagg ctgccaactg ccccgaacct cctgcatgaa gagtaggatg gacactgaca
    61141 atttccagat caaactgctc tgccacctga cgttcaacaa cgagagcccg attgacatgc
    61201 tcacaacctt gaactgctaa atggatacct ctactaccta gaatacccaa gatagtctcc
    61261 actatcagct caccaatctc ttgactggat tctttcccaa tctgaccacc tagcacctca
    61321 ctagaagata gacctaaaac aaaaaggacc ccctgcttca aattggtctt ttctaaaaca
    61381 tcttccacta cctgacgtgt ttctctttga atctgtgtct cgttcatctc tgttacctct
    61441 gttgtcactc ttctatcata ccgttttttc ttgtttttag caagatagac aacctataaa
    61501 gtctgcccaa ttacgcataa aactcccaga attgactggg agttagctag tttctattct
    61561 atttatatat atttcaactt tcgttccttt ttggggtcta gaatcaatct tcatctggta
    61621 attggctcca aaatgaagtt tgagccgttg atcgacattt tgaagaccaa ctcccccacg
    61681 tttgagttga ctttgactac tatcaccagc atcttggaag ccaacgccat catcctcaat
    61741 acggatgacc aatcccgaat cctgtttctg gacagaaagt ttaatatggc cctgaccttc
    61801 cttttcctta atgccatggt aaagagcatt ttctacaagg ggttgtagga ccagcttggg
    61861 taagactaaa ttatcaaagg caacattttc attaatttcg tattccagct tatctccata
    61921 gcgttgtttc tggataaaga gatactggcg gacatgattg atttcgtcag agagacaaat
    61981 caagtccttg ccttgattga gcgccaagcg gaaataggtt gccaaggact tggtcacctg
    62041 caccactcgc tgactatcat gaaattcagc catccagatg atggtgtcca aagtgttata
    62101 gaggaaatgt ggattaatct ggctcgaaag ggcttgaagt tggtactgac gggtcgtttc
    62161 ttcctggcta cgaatagcta ccatcaactg atcaatctga tccaacatag cattaaattg
    62221 gcgagttact tctctcagtt cataggcacc aacttccttg gcacgaagat tttgagcacc
    62281 agaagcaatt tccaacatgg tttctctcaa atccttcaaa ggagcaatcc agcgtttaag
    62341 actgaaccac actaagcaga gacaaacaag aagagatgtg acactggccc caagcaaggt
    62401 ccacaagagc tgactccgaa cctggtctaa cttttccaat gatgacacgc caagtaccgt
    62461 ccaatcagtt cctgcaatct tctcttgact gacgtaggat ttgtgaccag gagtataacc
    62521 ctgacctgtc tcgatgtagg gtttcatagc ctccattttg ctagacgaac tataaactgt
    62581 gtgttgagga tggtagacaa attcatggtt ttcattgata atgaaggcaa agccctgctg
    62641 ccccaactgg agttgattga gataggcttc cagagtttca taagaaatat ccaaacgaag
    62701 cacaccaaga ttggctccct ttgcatcaac aagttcttga gtgacagaaa tgacccactg
    62761 actatctgat ttacgagctg gagtcaaaac aggcatagct ccctgatgaa tagccttttg
    62821 gtaccaatcc tcagccatca tatcagagga agttttcatc tgcacactgt catctgtaga
    62881 aatgacctga ccagatttgg tcaccagcac aacagttttc aagtccttat ctgacttcaa
    62941 gatggtcaaa aacaaatctc ggattccctc gaccttgtct tgactgggat tctcagcata
    63001 ggccagaaca tccgtctgct gggtcaaacc agtcgaggtg gtttctagtt ttttgatata
    63061 agactgaata aagtggctag tctggctgat ggtcgtttgg ctgttgccct caatggtggc
    63121 ctcaatggct gaagaacttg attgatagta gaaagttcca accagagcta ggagaatgag
    63181 aaagaccaga aagatggaaa taaccattct aactaaaaga gaagaacgct tcatcggtct
    63241 tctcccttct taaactgacg aggtgtcaca cctgcaatct gcttaaaacg ttgggtaaaa
    63301 tagttcatat cttcaaaacc aaccttctct gcgatctcat aaatcttcag atctgtagtt
    63361 aaaagcaaga gcttggcttg tttaacacgt tctctcacca gataatcctg aaaaggcaag
    63421 cccaactctt tcttaatcaa ggaactcaga taggtcggac taaaacctaa gtcactggct
    63481 aaagacttta aactaaattg gctatcagcc agatgagact ggattttctg ggccatgttt
    63541 ccttcaaacc tattagtcaa taaatcttgt aactgctctt ctttctcttc cttgtctagt
    63601 ttttgtttga ttttccccaa catttcctca atatcctgac gagaaaaggg tttgagcagg
    63661 tagtcgtcca cacctagttt gacagcagac aaggcataat caaaatcatc gtaacctgtt
    63721 aaaaagacca aatgaacctg aggataggtt tctcgtacca gactggccaa ctggatgcca
    63781 tttagatgag gcatgttgat atcggttaaa atgatatctg gcacctgctt ttggatcaat
    63841 tcccaagcct gccttccatt ttcagcctga ccgatgattt ccatatcgta ggctgctaca
    63901 ttgaccagtt tagtcaaacc ttgtcttacc agatattcat cttctacgat taagattgtg
    63961 taggtcatgc tctgctcctt taccacttac tagtatcagt atagcaaaat tctcctctaa
    64021 ctgcttagga aagacctctt atactcaata aaaatcaaaa agtaaactag gaagatagcc
    64081 acaggtttct caaagtatag ctttgaggtt gtaaataaaa ctgacgaagt cagctcaaag
    64141 tatagctttg aggttgta
//
LOCUS       DAVBDR010000006        51675 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.006, whole genome shotgun sequence.
ACCESSION   DAVBDR010000006 DAVBDR010000000
VERSION     DAVBDR010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 51675)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 51675)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..51675
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.006"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            complement(54..362)
                     /locus_tag="VQ540_000397"
                     /pseudo
     CDS             complement(54..362)
                     /locus_tag="VQ540_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000996568.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GDP-mannose 4,6-dehydratase"
     gene            complement(604..900)
                     /locus_tag="VQ540_000398"
     CDS             complement(604..900)
                     /locus_tag="VQ540_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2544261.1"
                     /translation="MVKINKICSIQGSSVENEDIVGSQNQYFWIIGGATDLYNSKEEI
                     GYSVSEVVHILSESLSVNCKESKTLKQIFETALLEVKDEIGLNSYELTEYSKMK"
     gene            complement(884..3043)
                     /gene="pfbA"
                     /locus_tag="VQ540_000399"
     CDS             complement(884..3043)
                     /gene="pfbA"
                     /locus_tag="VQ540_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multi-ligand-binding adhesin PfbA"
                     /protein_id="HET2544262.1"
                     /translation="MLKIVKKLEVLMKYFVPNEVFSIRKLKVGTCSVLLAISILGSQG
                     ILSDEVVTSSSPMATKESSNAITNDLDNSPTVNQNRSAEMIASNSTTNGLDNSLSVNS
                     ISSNGTIRSNSQLDNRTVESTVISTNENKSYKEDVISDRIIKKEFEDTALSVKDYGAV
                     GDGIHDDRQAIQDAIDAAAQGLGGGNVYFPEGTYLVKEIVFLKSHTHLELNEKATILN
                     GINIKNHPSIVFMTGLFTDDGAQVEWGPTEDISYSGGTIDMNGALNEEGTKAKNLPLI
                     NSSGAFAIGNSNNVTIKNVTFKDSYQGHAIQIAGSKNVLVDNSRFLGQALPKTMKDGQ
                     IISKESIQIEPLTRKGFPYALNDDGKKSENVTIQNSYFGKSDKSGELVTAIGTHYQTL
                     STQNPSNIKILNNHFDNMMYAGVRFTGFTDVLIKGNRFDKKVKGESVHYRESGAALVN
                     AYSYKNTKDLLDLNKQVVIAENIFNIADPKTKAIRVAKDSAEYLGKVSDITVTKNVIN
                     NNSKETEQPNIELLRVSDNLVVSENSIFGGKEGIVIEDSKGKITVLNNQFYNLSGKYI
                     SFIKSNANGKESVIRDSDGNFNIVTENGLYKIVTNNLSDKNEKEKNKEEKQSNSNNVI
                     DSNQKNGEFNSSKDNRQMNDKIDNKQDNKTEEVNYKIVGDGRETENHINKSKEIVDVK
                     QKLPKTGSNKIMELFLTVTGIGLLLTLKGLKYYGKDK"
     gene            complement(4173..5399)
                     /locus_tag="VQ540_000400"
     CDS             complement(4173..5399)
                     /locus_tag="VQ540_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001134527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegT/DnrJ/EryC1/StrS aminotransferase family
                     protein"
                     /protein_id="HET2544263.1"
                     /translation="MPNYNIPFSPPDITEAEIAEVADTLRSGWITTGPKTKELERRLS
                     LYTQTPKTVCLNSATAALELILRVFEVGPGDEVIVPAITYTASCSVITHVGATPVMVD
                     IQADTFEMDYDLLEQAITEKTKVIIPVELAGIVCDYDRLFQVVEKKRDFFTASSKWQK
                     AFNRIVIVSDSAHALGSTYKGQPSGSIADFTSFSFHAVKNFTTAEGGSATWKANPVID
                     DEEMYKEFQILSLHGQTKDALAKMQLGSWEYDIVTPAYKCNMTDIMASLGLVQLDRYP
                     SLLQRRKDIVDRYDSGFAGSRIHPLAHKTETVESSRHLYITRVEGASLEERNLIIQEL
                     AKAGIASNVHYKPLPLLTAYKNLGFDMTNYPKAYAFFENEITLPLHTKLSDEEVDYII
                     ETFKTVSEKVLTLSKK"
     gene            complement(5442..6134)
                     /locus_tag="VQ540_000401"
     CDS             complement(5442..6134)
                     /locus_tag="VQ540_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000922225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HET2544264.1"
                     /translation="MLKWEDLPVEMKSSEVESYYQLVSKRKGSLIFKRCLDWVLALVL
                     LVLTSPIFLILSIWIKLDSKGPVIYKQERVTQYNRRFKIWKFRTMVTDADKKGNLVTS
                     ANDSRITKVGNFIRRVRLDELPQLVNVLKGEMSFVGTRPEVPRYTEQYSTEMMATLLL
                     QAGITSPASINYKDEDTIISQMTEKGLSVDQAYVEHVLPEKMRYNLAYLREFSFFGDI
                     KIMFQTVFKVLK"
     gene            complement(6320..8071)
                     /locus_tag="VQ540_000402"
     CDS             complement(6320..8071)
                     /locus_tag="VQ540_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2544265.1"
                     /translation="MQNKQEQWAVLKRLMSYLKPYRLLTFLALSFLLATTVIKSVIPL
                     VASHFIDQYLSNLNQLAVTVLLVYYGLYILQTVVQYVGNLLFARVSYSIVRDIRRDAF
                     ANMEKLGMSYFDKTPAGSIVSRLTNDTETISDMFSGILSSFISAVFIFLTTLYTMLVL
                     DFRLTALVLLFLPLIFLLVNLYRKKSVKIIEKTRSLLSDINSKLAENIEGIRIIQAFN
                     QEKRLQAEFDEINQEHLVYANRSVALDALFLRPAMSLLKLLGYAVLMAYFGYRGLSIG
                     ITAGTMYAFIQYINRLFDPLIEVTQNFSTLQTSMVSAGRVFALVDERTYEPLQENGQA
                     KVQEGNIRFEHVCFSYDGKHPILDDISFSVNKGETIAFVGHTGSGKSSIINVLMRFYE
                     FQSGRVLLDDVDIRDFSQEELRKNIGLVLQEPFLYHGTIKSNIAMYQEISDEQVQAAA
                     AFVDADSFIQELPQGYDSPVSERGSSFSTGQRQLLAFARTVASQPKILILDEATANID
                     SETESLVQASLAKMRQGRTTIAIAHRLSTIQDANCIYVLDKGRIIESGTHEELLALGG
                     TYHKMYSLQAGAMAYTL"
     gene            complement(8061..9806)
                     /locus_tag="VQ540_000403"
     CDS             complement(8061..9806)
                     /locus_tag="VQ540_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET2544266.1"
                     /translation="MSIIQKLWWFFKLEKHRYLVGIVALVLVSVLNLIPPMVMGRVID
                     AITSGQLTQQDLLLSLFYLLLAAFGMYYLRYVWRMYILGTSYCLGQIMRSRLFKHFTK
                     MSPAFYQTYRTGDLMAHATNDINALTRLAGGGVMSAVDASITALVTLLTMLFSISWQM
                     TLVAILPLPFMAYATSRLGRKTHKAFGESQAAFSELNNKVQESVSGIKVTKSFGYQAD
                     ELKSFQAVNELTFQKNLQTMKYDSLFDPMVLLFVGSSYVLTLLVGSLMVQEGQITVGN
                     LVTFISYLDMLVWPLMAIGFLFNTTQRGKVSYQRIENLLSQESPVQDPEFPLDGIENG
                     RLEYAIDSFAFENEETLTDIHFSLAKGQTLGLVGQTGSGKTSLIKLLLREYDVDKGAI
                     YLNGHDIRDYRLTELRSLMGYVPQDQFLFATSILDNIRFGNPNLPLSEVEEATKLARV
                     YQDIVDMPQGFDTLIGEKGVSLSGGQKQRLAMSRAMILNPDILILDDSLSAVDAKTEY
                     AIIDNLKETRKDKTTIITAHRLSAVVHADFILVLQNGQIIERGRHEDLLAMDGWYAQT
                     YQSQQLEMKGEEDAE"
     gene            complement(10012..10308)
                     /locus_tag="VQ540_000404"
     CDS             complement(10012..10308)
                     /locus_tag="VQ540_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001276342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HET2544267.1"
                     /translation="MSASDVALKLRSQGIFQMKQVKRAVQEQNGQLIVVQMGDENPKY
                     PVVTDGVIQVDVLESIGRSEEWLLDNLSKQGHDNVANIFIAEYDKGAVTVVTYE"
     gene            complement(10461..10917)
                     /locus_tag="VQ540_000405"
                     /pseudo
     CDS             complement(10461..10917)
                     /locus_tag="VQ540_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730499.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3290 family protein"
     gene            11051..11878
                     /gene="xth"
                     /locus_tag="VQ540_000406"
     CDS             11051..11878
                     /gene="xth"
                     /locus_tag="VQ540_000406"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006596696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HET2544268.1"
                     /translation="MKLISWNIDSLNAALTSDSARAKLSQEVLQTLVAENADIIAIQE
                     TKLSAKGPTKKHVEILEELFPGYENTWRSSQEPARKGYAGTMFLYKKELTPTISFPEI
                     GAPSTMDLEGRIITLEFDAFFVTQVYTPNAGDGLKRLEERQVWDVKYAEYLAELDKEK
                     PVLATGDYNVAHNEIDLANPASNRRSPGFTDEERAGFTNLLATGFTDTFRHVHGDVPE
                     RYTWWAQRSKTSKINNTGWRIDYWLTSNRIADKVTKSDMIDSGARQDHTPIVLEIDL"
     gene            11890..12033
                     /locus_tag="VQ540_000407"
     CDS             11890..12033
                     /locus_tag="VQ540_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HET2544269.1"
                     /translation="MDYNAVIPEFLVSNIEQSRSFYCGLLGFRIEYQRSEENFLFLLK
                     SVN"
     gene            12033..12272
                     /locus_tag="VQ540_000408"
     CDS             12033..12272
                     /locus_tag="VQ540_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HET2544270.1"
                     /translation="MLEEGTKDQLAELTYPFGRGVNLSFGIKDVPKLYQKVMEANYPI
                     YRPLTKRKFRVSDPYIYPHKFAVLDPDGYFLRFSE"
     regulatory      12656..12751
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            13151..13732
                     /locus_tag="VQ540_000409"
     CDS             13151..13732
                     /locus_tag="VQ540_000409"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HET2544271.1"
                     /translation="MKLLEERILKDGHILGDNILKVDSFLTHQVDFSLMREIGKVFAE
                     KFAAAGITKVVTIEASGIAPAVFTAEALNVPMIFAKKAKNITMNEGILTAQVYSFTKQ
                     VTSTVSIAGKFLSPEDKVLIIDDFLANGQAAKGLIQIIEQAGATVQAIGIVIEKSFQD
                     GRDLLEKAGYPVLSLARLDRFENGQVVFKEADL"
     gene            13732..14994
                     /locus_tag="VQ540_000410"
     CDS             13732..14994
                     /locus_tag="VQ540_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001194492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HET2544272.1"
                     /translation="MQTQEKHSQAAVLGLQHLLAMYSGSILVPIMIATALGYSAEQLT
                     YLISTDIFMCGVATFLQLQLNKYFGIGLPVVLGVAFQSVAPLIMIGQSHGSGAMFGAL
                     IASGIYVVLVSGIFSKVANLFPSIVTGSVITTIGLTLIPVAIGNMGNNVPEPTGQSLL
                     LSAITVLIILLINIFTKGFIKSISILIGLVVGTAIAATMGLVDFSPVAVAPLVHVPTP
                     LYFGMPTFEISSIVMMCIIATVSMVESTGVYLALSDITKDPIDSTRLRNGYRAEGLAV
                     LLGGIFNTFPYTGFSQNVGLVKLSGIKKRLPIYYAAGFLVLLGLLPKFGALAQIIPSS
                     VLGGAMLVMFGFVSIQGMQILARVDFANNEHNFLIAAVSIAAGVGLNNSNLFVSMPTA
                     FQMFFSNGIVVASLLAIVLNAVLNHKKK"
     gene            complement(15081..15947)
                     /locus_tag="VQ540_000411"
     CDS             complement(15081..15947)
                     /locus_tag="VQ540_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000815109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II restriction endonuclease"
                     /protein_id="HET2544273.1"
                     /translation="MKQTRNFDEWLSTMTDTVADWTYYTDFPKVYKNVSSIKVALNIM
                     NSLIGSKNIQEDFLDLYQNYPEILKVVPLLIAKRLRDTIIVKDPIKDFYFDFSKRNYS
                     IEEYTMFLEKSGIFDLLQNHLVSNLVDYVTGVEVGMDTNGRKNRTGDAMENIVQSYLE
                     AEGYILGENLFKEIEQNEIEEIFSVDLSAITNDGNTVKRFDFVIKNEQVLYLIEVNFY
                     SGSGSKLNETARSYKMIAEEIKAIPNVEFMWITDGQGWYKAKNNLRETFDILPFLYNI
                     NDLEHNILKNLK"
     gene            complement(15934..16704)
                     /locus_tag="VQ540_000412"
     CDS             complement(15934..16704)
                     /locus_tag="VQ540_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HET2544274.1"
                     /translation="MTKPYYNKNKMILVHSDTFKFLSKMKPESMDMIFADPPYFLSNG
                     GISNSGGQVVSVDKGDWDKISSFEEKHEFNRKWIRLAKEVLKPNGTVWISGSLHNIYS
                     VGMALEQEGFKILNNITWQKTNPAPNLSCRYFTHSTETILWARKNDKKARHYYNYDLM
                     KELNDGKQMKDVWTGSLTKKVEKWAGKHPTQKPEYLLERIILASTKEGDYILDPFVGS
                     GTTGVVAKRLGRRFIGIDAEKEYLKIARKRLEAENETN"
     gene            complement(16730..17584)
                     /locus_tag="VQ540_000413"
     CDS             complement(16730..17584)
                     /locus_tag="VQ540_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012972462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA adenine methylase"
                     /protein_id="HET2544275.1"
                     /translation="MKIKEIKKVTLQPFTKWTGGKRQLLPVIRELMPKTYNRYFEPFV
                     GGGALFFDLAPKDAVINDFNAELINCYQQIKDNPQELIEILKVHQEYNSKEYYLDLRS
                     ADRDERIDMMSEVQRAARILYMLRVNFNGLYRVNSKNQFNVPYGRYKNPKIVDEELIS
                     AISVYLNNNQLEIKVGDFEKAIVDVRTGDFVYFDPPYIPLSETSAFTSYTHEGFSFAD
                     QVRLRDAFKRLSDTGAYVMLSNSSSALVEELYKDFNIHYVEATRTNGAKSSSRGKISE
                     IIVTNYEK"
     gene            complement(17741..18145)
                     /locus_tag="VQ540_000414"
     CDS             complement(17741..18145)
                     /locus_tag="VQ540_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HET2544276.1"
                     /translation="MKDFHFDAISAFENYEIEKMRDGHVVVTTKVVNSSLNYYGNAHG
                     GYLFTLCDQISGLVVISLGLDGVTLQSSINYLKAGKLDDVLTIKGECVHQGRTTCVMD
                     VDITNQEGRNVCKATFTMFVTGQRSEERRVRI"
     gene            complement(18215..19696)
                     /locus_tag="VQ540_000415"
     CDS             complement(18215..19696)
                     /locus_tag="VQ540_000415"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HET2544277.1"
                     /translation="MTLVDKFVTHVISESSFEEMDRIYLTNRVLARVGEGVLEVETNL
                     DKLIDLKDQLVEEAVRLETIEDSQTAREILGTELMDLVTPCPSQVNRDFWEAYAYSPE
                     QAIEDFYQLSQKNDYIKLKAIAKNIVYRVPSDYGELEITINLSKPEKDPKEIAVAKLV
                     QASNYPQCQLCLENEGYHGRVNHPARSNHRIIRFEMVGQEWGFQYSPYAYFNEHCIFL
                     DGQHRPMAISRQSFERLLAIVEQFPGYFAGSNADLPIVGGSILTHDHYQGGRHVFPME
                     LAPLQKTFRFAGFEQVKAGIIKWPMSVLRLTSDSKEDLINLADKIFQEWRQYSDSSVQ
                     ILAETDGTPHHTITPIARKRDGQFELDLVLRDNQTSADHPDGIYHPHKDVQHIKKENI
                     GLIEVMGLAILPPRLKEEVEQVASYLVGEAVTVADYHQEWADQLKSQHPDLTDKEKAL
                     AIVKDSVGAIFARVLEDAGVYKQTEQGQTAFMRFVEHVGILLD"
     gene            complement(19715..20893)
                     /locus_tag="VQ540_000416"
     CDS             complement(19715..20893)
                     /locus_tag="VQ540_000416"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HET2544278.1"
                     /translation="MAQHLTTEALRKDFLAVFGQEADQTFFSPGRINLIGEHTDYNGG
                     HVFPAAISLGTYGAARKRDDQVLRFYSANFEDKGIIEVPLADLKFEKEHNWTNYPKGV
                     LHFLQEAGHVIDKGFDFYVYGNIPNGAGLSSSASLELLTGVVAEHLFDLKLERLDLVK
                     IGKQTENNFIGVNSGIMDQFAIGMGADQRAIYLDTNTLEYDLVPLDLKDNVVVIMNTN
                     KRRELADSKYNERRAECEKAVEELQVALDIQTLGELDEWAVDQYSYLIKDENRLKRAR
                     HAVFENQRTLKAQAALQAGDLETFGRLMNASHVSLEHDYEVTGLELDTLVHTAWAQEG
                     VLGARMTGAGFGGCAIALVQKDTVEAFKEAVGKHYEEVVGYAPSFYIAEVAGGTRVLD
                     "
     gene            21058..22065
                     /gene="galR"
                     /locus_tag="VQ540_000417"
     CDS             21058..22065
                     /gene="galR"
                     /locus_tag="VQ540_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator GalR"
                     /protein_id="HET2544279.1"
                     /translation="MATLKDIAQLASVSIATVSRVLNRDQSLSVTEETRHRILTVAEE
                     LGYTKHLKTGESHKPKQKIAIIQWVSEQGELDDLYYYQIRLGIEKRAQELDYDILRYF
                     NDHPFTLSEEVIGILCIGKFSRAQISAFEEYQKPLVFLDSDTLSLGHTCIITDFYTAM
                     KQVVDYFLSQGMDRIGILTGLEETTDQEEIIQDKRLENFRNYSQAKGIYHDELVFQGN
                     FTAQSGYDLMKEAIQNLGDQLPPAFFAASDSLAIGALRALQEAGISLPDRVSLISFND
                     TSLTKQVYPPLSSITVYTEEMGRAGMDILNKEVLHDRKIPSLTMLGTRLTLRESTLNQ
                     E"
     gene            complement(22111..23148)
                     /locus_tag="VQ540_000418"
     CDS             complement(22111..23148)
                     /locus_tag="VQ540_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HET2544280.1"
                     /translation="MKSAVYTKAGQVGLASIERPQIIEADDVIIRVVRACVCGSDLWR
                     YRNPETKAGHKNSGHEAIGIVEEAVEAITTVKPGDFVIVPFTHGCGECDACLAGFDGS
                     CDNHIGNNLGGDFQAEYIRFHYANWALVKIPGQPSDYTEGMLQSLLTLADVMPTGYHA
                     ARVANVQKGDKVVVIGDGAVGQCAVIAAKMRGASQIILMSRHEDRQKMAMESGATAVV
                     AERGQEGITKVREILGGGADAALECVGTEAAIEQALGVLHNGGRMGFVGVPHYNNRAL
                     GSTFMQNISVAGGAASATTYDKQFLLKAVLDGDINPGRVFTSSYKLEDIDQAYKDMDE
                     RKTIKSMIVIE"
     gene            complement(23149..23502)
                     /locus_tag="VQ540_000419"
     CDS             complement(23149..23502)
                     /locus_tag="VQ540_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HET2544281.1"
                     /translation="MNIKSASDLLGISADTIRYYERVGLVPPITRTATGIRDFQDQDI
                     EALEFIKCFRSAGVSVDSLVDYMSLYQKGDETREERLGILEEEKQKLEERLSQLQTAL
                     NRLNLKIKLYKEGKF"
     gene            complement(23746..24636)
                     /locus_tag="VQ540_000420"
     CDS             complement(23746..24636)
                     /locus_tag="VQ540_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000645104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HET2544282.1"
                     /translation="MKAKYAVWVAFFLNLTYAIVEFIAGGVFGSSAVLADSVHDLGDA
                     IAIGISAFLETISNREEDNQYTLGYKRFSLLGALVTAVILVTGSVLVILENVTKILHP
                     QPVNDEGILWLGIIAITINLLASLVVGKGKTKNESILSLHFLEDTLGWVAVILMAIVL
                     RFTDWYILDPLLSLVISFFILSKALPRFWSTLKIFLDAVPEGLDIKQVKSGLERLDNV
                     ASLNQLNLWTMDALEKNAIVHVCLKEMEHMETCKESIRIFLKDCGFQNITIEIDADLE
                     THQTHKRKVCDLERSYEHQH"
     gene            24769..25305
                     /locus_tag="VQ540_000421"
     CDS             24769..25305
                     /locus_tag="VQ540_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HET2544283.1"
                     /translation="MTNIDRRISKTKKAIYQAFIQLLNAKGYEATTVQDIIDLADVGR
                     STFYCHYESKELLLDQLCRYLFHHLFEREQAISTEDYLAHLFLHFHKNQDHITSLLFS
                     KNDYFLRQLHKELEHHVYSVLADNLKEAHPNLPTSYLQHLVMSNFIETLTWWLKKGQD
                     FTDQEVVQFYLDLLIPKN"
     gene            complement(25472..26278)
                     /locus_tag="VQ540_000422"
     CDS             complement(25472..26278)
                     /locus_tag="VQ540_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide riboside transporter PnuC"
                     /protein_id="HET2544284.1"
                     /translation="MHTYLQKKIENIKTTLGEMSGGYRRMVAAMADLGFSGTMKAIWD
                     DLFAHRSFAQWIYLLVLGSFPLWLELVYEHRIVDWIGMICSLTGIICVIFVSEGRASN
                     YLFGLINSVIYLILALQKGFYGEVLTTLYFTVMQPIGLLVWIYQAQFKKEKQEFVARK
                     LDGKGWTKYLSISVLWWLAFGFIYQSIGANRPYRDSITDATNGVGQILMTAVYREQWI
                     FWAATNVFSIYLWWGESLQIQGKYLIYLINSLVGWYQWSKAAKQNTDLLN"
     gene            complement(26623..28143)
                     /locus_tag="VQ540_000423"
     CDS             complement(26623..28143)
                     /locus_tag="VQ540_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HET2544285.1"
                     /translation="MTNLIATFQDRFSDWLTALSQHLQLSLLTLLLAILLAIPLAVFL
                     RYHEKLADWVLQIAGIFQTIPSLALLGLFIPLMGIGTLPALTALVIYAIFPILQNTIT
                     GLKGIDPNLQEAGIAFGMTRWERLKKFEIPLAMPVIMSGIRTAAVLIIGTATLAALIG
                     AGGLGSFILLGIDRNNASLILIGALSSAVLAIAFNFLLKVMEKAKLRTIFSGFALVAL
                     LLGLSYSPALLVQKEKENLVIAGKIGPEPEILANMYKLLIEENTSMTATVKPNFGKTS
                     FLYEALKKGDIDIYPEFTGTVTESLLQPSPKVSHEPEQVYQVARDGIAKQDHLAYLKP
                     MSYQNTYAVAVPKKIAQEYGLKTISDLKKVEGQLKAGFTLEFNDREDGNKGLQSMYGL
                     NLNVATMEPALRYQAIQSGDIQITDAYSTDAELERYDLQVLEDDKQLFPPYQGAPLMK
                     EALLKKHPELERVLNTLAGKITESQMSQLNYQVGVEGKSAKQVAKEFLQEQGLLKK"
     gene            complement(28136..28864)
                     /locus_tag="VQ540_000424"
     CDS             complement(28136..28864)
                     /locus_tag="VQ540_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2544286.1"
                     /translation="MIEYKNVALRYTEKDVLRDVNLQIEDGEFMVLVGPSGSGKTTML
                     KMINRLLEPTDGNIYMDGKRIKDYDERELRLSTGYVLQAIALFPNLTVAENIALIPEM
                     KGWSKEEITKKTEELLAKVGLPVAEYGHRLPSELSGGEQQRVGIVRAMIGQPKIFLMD
                     EPFSALDAISRKQLQVLTKELHKEFGMTTIFVTHDTDEALKLADRIAVLQDGEIRQVA
                     NPETILKAPATDFVADLFGGSVHD"
     gene            complement(28879..29643)
                     /locus_tag="VQ540_000425"
     CDS             complement(28879..29643)
                     /locus_tag="VQ540_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HET2544287.1"
                     /translation="MSQQVKNAHNLYIHAIQDGRVAEAQAQSVGDTYIQHSTGVPDGK
                     EGFAAFFADFFERHPERQIKIVRTIEDGNLVFVHVHQYLNGGEAQWVTTDTFRADENG
                     RIVEHWDVVDYYRTPENDQLDQIFGDFEIKDLDKKAENKKLVRRFLTEIFQNGELEQW
                     SDYVADDLIQHNHDIGQGSAAYKNYVAEYSVTFDFVFQLLGQGNYVVSYGQTQIDGVA
                     YAQYDIFRLENGKIVEHWDNKEVMPKVEDLTNRGKF"
     gene            complement(29647..30090)
                     /locus_tag="VQ540_000426"
     CDS             complement(29647..30090)
                     /locus_tag="VQ540_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HET2544288.1"
                     /translation="MKDSHLLAHHIRLLNGRIFQKLLSQDPEALYRGEQGKILAVLWN
                     SETGCATATDIALATGLANNTLTTMIKKLEEQKLVIVSPCGKDKRKKYLVLTELGKFQ
                     KEVGHRVSQKLDTIFYKGFSEEEIHQFEGFQERILANLKEKGNEV"
     gene            complement(30772..31068)
                     /locus_tag="VQ540_000427"
     CDS             complement(30772..31068)
                     /locus_tag="VQ540_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HET2544289.1"
                     /translation="MAEPNLESLIKDLYNHARHDLSEDLVAALLETAKKLPTTNEQLQ
                     AVRLSGLVNRELLLNPKHPAPELLNLARFIKREEAKYRGTATSALMYEELFKML"
     gene            complement(31090..32154)
                     /gene="pepA"
                     /locus_tag="VQ540_000428"
     CDS             complement(31090..32154)
                     /gene="pepA"
                     /locus_tag="VQ540_000428"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HET2544290.1"
                     /translation="MTTLFSKIKEVTELAAVSGHEAPVRAYLREKLTPHVDEVVTDGL
                     GGIFGIKHSEAVDAPRVLVASHMDEVGFMVSEIKPDGTFRVVEIGGWNPMVVSSQRFK
                     LLTRDGHEIPVISGSVPPHLTRGKGGPTMPAIADIVFDGGFADKAEAESFGIRPGDTI
                     VPDSSAILTANEKNIISKAWDNRYGVLMVSELAEALSGQKLGNELYLGSNVQEEVGLR
                     GAHTSTTKFDPEVFLAVDCSPAGDVYGGQGKIGDGTLIRFYDPGHLLLPGMKDFLLTT
                     AEEAGIKYQYYCGKGGTDAGAAHLKNGGVPSTTIGVCARYIHSHQTLYAMDDFLEAQA
                     FLQALVKKLDRSTVDLIKHY"
     gene            32555..33256
                     /gene="galE"
                     /locus_tag="VQ540_000429"
     CDS             32555..33256
                     /gene="galE"
                     /locus_tag="VQ540_000429"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HET2544291.1"
                     /translation="MTKTILVTGGTSYIGSHTVKALLNAGYKVHVLDNLSTGNRAAVD
                     SRASFKELDVYDASALKAYLEENQIDAVLHCAGEIVVSESIENPSKYFTANVAGMNQV
                     LKVLSEVGIQKIMFSSTASLYGNNCIDKPVTEDTLLDPVNPYAETKLMGERMIYWMAN
                     RYDWKYVIFRYFNVAGAEMDASNGLRVKNPTHIIPNINKTALGQNDSLKIFGDDYDTR
                     DGSCIRDYIYVLDLA"
     gene            33679..34638
                     /locus_tag="VQ540_000430"
     CDS             33679..34638
                     /locus_tag="VQ540_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2544292.1"
                     /translation="MKLSHYLIGLLLLLVFLSISIGTSDFSWGKLFDFDQQTWLLFQE
                     SRLPRTISILLTASSMSMAGLLMQTITQNQFAAPSTVGTTEAAKLGMVLSLFVFPSAS
                     LTQKMLFAFVSSIVFTLFFLAFMTIFTVKERWMLPLIGIIYSGIIGSVTEVIAYRFNL
                     VQSMTAWTQGSFSMIQTHQYEWLFLGLIILITVWKLSQTFTIMNLGKEISESLGISYS
                     LLEKLALFLVALTTSVTMITVGGLPFLGVIVPNLVRKRYGDNLSQTKLMVALVGANLV
                     LACDILSRVLIRPYELSVSLLLGIIGSLGFILLLWRGGRKDAD"
     gene            34628..35584
                     /locus_tag="VQ540_000431"
     CDS             34628..35584
                     /locus_tag="VQ540_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HET2544293.1"
                     /translation="MQTKSKHTKLFWILIILAIGACLLYFWPITHLSAFAWKLRSQKI
                     IVYLLVAIATGISTISFQTLTENRFLTPSILGIESFYVLLQTLLLVFESKFLQLGKSP
                     ILEFLVLLLVQSLFFLTLQGYLKTLMKQDLVFILLICLALRSLFRNISTFLQVLMDPN
                     EYDKLQNSLFASFQHLNTSILAIGSLIILALTIFFFRKAVVLDVLHLQRETAQILGLD
                     VEKEQKELLWGIVLLTSTATALVGPMAFFGFMLANLTYLIVKDYQHKLLFIVAILVGF
                     ISLTLGQALIERVFALEIRISMIIESVGGFLFFILLYRRSRQ"
     gene            35581..36333
                     /locus_tag="VQ540_000432"
     CDS             35581..36333
                     /locus_tag="VQ540_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000764290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2544294.1"
                     /translation="MKLENIDKSIQKQDILQGISLEVSPQKLTAFIGPNGAGKSTLLS
                     IMSRLTKKDQGVLSIKGREIESWNSQELAQELTILKQKINYQAKLTVEELVSFGRFPY
                     SRGRLRSEDWEKIRETLNYLELTNLKDRYINSLSGGQLQRVFIAMVLAQDTDFILLDE
                     PLNNLDIKQSVSMMQILRRLVEELGKTIIIVLHDINMASQYADEIVAFKDGQVFSKGS
                     TDQIMQADLLSQLYEIPITLADINDKKICIYS"
     gene            36429..37394
                     /locus_tag="VQ540_000433"
     CDS             36429..37394
                     /locus_tag="VQ540_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HET2544295.1"
                     /translation="MKTSLKLYFTALVASFLLLLGACSTNSSTSQTETSSSAPTEVTI
                     KSSLDEVKLSKVPEKIVTFDLGAADTIRALGFEKNIVGMPTKTVPTYLKDLVGTVKNV
                     GSMKEPDLEAIAALEPDLIIASPRTQKFVDKFKEIAPTVLFQASKDDYWTSTKANIES
                     LASAFGETGTQKAKEELAKLDKSIQEVATKNESSDKKALAILLNEGKMAAFGAKSRFS
                     FLYQTLKFKPTDTKFEDSRHGQEVSFESVKEINPAILFVINRTLAIGGDNSSNDGVLE
                     NALIAETPAAKNGKIIQLTPDLWYLSGGGLESTKLMIEDIQKALK"
     gene            complement(37619..37861)
                     /gene="yidD"
                     /locus_tag="VQ540_000434"
     CDS             complement(37619..37861)
                     /gene="yidD"
                     /locus_tag="VQ540_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HET2544296.1"
                     /translation="MKRILIAPVRFYQRFISPVFPPSCRFELTCSNYMIQAIEKHGFK
                     GVLMGLARILRCHPWSKTGKDPVPDHFSLKRNQEGE"
     gene            complement(37861..38583)
                     /locus_tag="VQ540_000435"
     CDS             complement(37861..38583)
                     /locus_tag="VQ540_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HET2544297.1"
                     /translation="MRINKYIAHAGVASRRKAEELIKQGLVTVNGQVVRELATTIKSG
                     DKVEVEGQPIYNEEKVYYLLNKPRGVISSVTDDKGRKTVVDLLPNVKERIYPVGRLDW
                     DTSGVLILTNDGDFTDEMIHPRNEIDKVYVARVKGVANKDNLRPLTRGLEIDGKKTKP
                     AVYEILKVDPVKNRSVVQLTIHEGRNHQVKKMFEAVGLQVDKLSRTRFGHLDLTGLRP
                     GESRRLNKKEISQLHTMAVTKK"
     gene            complement(38570..39139)
                     /locus_tag="VQ540_000436"
     CDS             complement(38570..39139)
                     /locus_tag="VQ540_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein B"
                     /protein_id="HET2544298.1"
                     /translation="MSTLAKIEALLFVAGEDGIRVRQLAELLSLPPTGIQQSLGKLAQ
                     KYEKDPDSSLALIETSGAYRLVTKSQFAEILKEYSKAPINQSLSRAALETLSIIAYKQ
                     PITRIEIDAIRGVNSSGALAKLQAFDLIKEDGKKEVLGRPNLYVTTDYFLDYMGINHL
                     EELPVIDELEIQAQESQLFGERIEEDENQ"
     gene            complement(39158..39886)
                     /locus_tag="VQ540_000437"
     CDS             complement(39158..39886)
                     /locus_tag="VQ540_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000351912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HET2544299.1"
                     /translation="MDIKLKDFEGPLDLLLHLVSKYQMDIYDVPITEVIEQYLAYVST
                     LQAMRLEVTGEYMVMASQLMLIKSRKLLPKVAEVTDLGDDLEQDLLSQIEEYRKFKLL
                     GEHLEAKHQERAQYYSKAPTELIYEDAELVHDKTTIDLFLAFSNILAKKKEEFAQNHT
                     TILRDEYKIEDMMIIVKESLIGRDQLRLQDLFKEAQNVQEVITLFLATLELIKTQELI
                     LVQEESFGDIYLMEKKEESQVPQS"
     gene            complement(39886..40626)
                     /gene="xerD"
                     /locus_tag="VQ540_000438"
     CDS             complement(39886..40626)
                     /gene="xerD"
                     /locus_tag="VQ540_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HET2544300.1"
                     /translation="MPMRDRISAFLEEKQGLSVNSKQSYKYDLEQFLDMVGERISETS
                     LKIYQAQLANLKISAQKRKISACNQFLYFLYQKGEVDSFYRLELAKQAEKKTEKPEIL
                     YLDSFWQESDHPEGRLLALLILEMGLLPSEILAIKVADINLDFQVLRISKASQQRIVT
                     IPTALLSELEPLMGQTYLFERGEKPYSRQWAFRQLESFVKEKGFPSLSAQVLREQFIL
                     RQIENKVDLYEIAKKLGLKTVLTLEKYR"
     gene            complement(40617..41078)
                     /locus_tag="VQ540_000439"
     CDS             complement(40617..41078)
                     /locus_tag="VQ540_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000560721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HET2544301.1"
                     /translation="MIAKEFETFLLGQEETFLTPAKNLAVLIDTHNADHATLLLSQMT
                     YTRVPVVTDEKQFVGTIGLRDIMAYQMEHDLSQEIMADTDIVHMTKTDVAVVSPDFTI
                     TEVLHKLVDESFLPVVDAEGIFQGIITRKSILKAVNALLHDFSKEYEIRCQ"
     gene            complement(41075..41596)
                     /locus_tag="VQ540_000440"
     CDS             complement(41075..41596)
                     /locus_tag="VQ540_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001118598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HET2544302.1"
                     /translation="MAKQTIIVMSDSHGDSLIVEEVRDRYVGKVDAVFHNGDSELRPD
                     SPLWEGIRVVKGNMDFYAGYPERLVTELGSTKIIQTHGHLFDINFNFQKLDYWAQEEE
                     AAICLYGHLHVPSAWLEGKILFLNPGSISQPRGTIRECLYARVEIDDSYFKVDFLTRD
                     HEVYPGLSKEFSR"
     gene            complement(41572..42543)
                     /locus_tag="VQ540_000441"
     CDS             complement(41572..42543)
                     /locus_tag="VQ540_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000182414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-triphosphate diphosphatase"
                     /protein_id="HET2544303.1"
                     /translation="MTNKIYEYKDDQDWYVGSYSIFGGVNSLSDYKTDFPLFEFSKIF
                     GDEEYGFPLSVTVLRYGSTYRLFSFVVDMLNQEMGRNLEVIQRHGALLLVENGQLLYV
                     ELPKEGVNVHDFFETSKVRETLLIATRNEGKTKEFRAIFDKLGYDVENLNDYPDLPEV
                     AETGMTFEENARLKAETISQLTGKMVLADDSGLKVDVLGGLPGVWSARFAGVGATDRE
                     NNAKLLHELAMVFELKDRSAQFHTTLVVASPNKESLVVEADWSGYINFEPKGENGFGY
                     DPLFLVGETGKSSAELTLEEKNSQSHRALAVKKLLEVFPSWQSKPSL"
     gene            complement(42540..43334)
                     /gene="racE"
                     /locus_tag="VQ540_000442"
     CDS             complement(42540..43334)
                     /gene="racE"
                     /locus_tag="VQ540_000442"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000370386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HET2544304.1"
                     /translation="MDNRPIGFLDSGVGGLTVVRELMRQLPHEEIVYIGDSARAPYGP
                     RPAEQIREYTWQLVNFLLTKDVKMIVIACNTATAVVWEEIKAQLDIPVLGVILPGASA
                     AIKSSQGGKIGVIGTPMTVQSDIYRQKIHDLDPDLQVESLACPKFAPLVESGALSTSV
                     TKKVVYETLRPLVGKVDSLILGCTHYPLLRPIIQNVMGPKVQLIDSGAECVRDISVLL
                     NYFEINRGRDAGPLHHRFYTTASSQSFAQIGEEWLEKEIYVEHVEL"
     gene            complement(43541..43789)
                     /locus_tag="VQ540_000443"
     CDS             complement(43541..43789)
                     /locus_tag="VQ540_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000364981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HET2544305.1"
                     /translation="MDLLLAIVLIVLAFLGGALGGMYLVRKQIEKEFADNPRLNAEAV
                     RTLLSANGQKPSEAKVQQVYHQIIRQQKAALANNKKKK"
     gene            complement(43931..45556)
                     /gene="treC"
                     /locus_tag="VQ540_000444"
     CDS             complement(43931..45556)
                     /gene="treC"
                     /locus_tag="VQ540_000444"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HET2544306.1"
                     /translation="MTLDKGKVVYQIYPKSYKDTTGNGIGDFRGIIGKIPYLAKLGVD
                     MVWLNPFYPSPQRDNGYDISDYMAVDPLFGDMADFEEMVCIGKEHKIDFMLDMVLNHC
                     STEHEWFQKALAGDKYYQDFFFIQDQPTDWQSKFGGSAWAPFGDTGKYYLHLFDETQA
                     DLNWRNPNVRKELFKVVNFWRDKGVKGFRFDVINLIGKDEVSVDCPENEGKPAYTDKP
                     IVHNYLRMMNQATFGSDDSFMTVGEMSSTTMENCVLYSSPDRQELSMTFNFHHLKVDY
                     KDGQKWTLAPFDFEELKSLYHSWGKEMSDKDGWSALFWNNHDQPRALNRFVDIQNFRK
                     EGATMLAASIHLSRGTPYIYMGEEIGMIDPDYDSMADYVDVESLNAYQMLLEEGKSQQ
                     EAFQIIQAKSRDNSRIPMQWDASENAGFSTGTPWLKAGKSYKDINVENEIQGPIFTFY
                     QDLIRLRKEMPIISEGSYKPAFEDSKQVYAFERQFEDQKLLVLNNFYAKEVEIDLPAV
                     YQNGQILISNYEDAEVSEKILLKPYQTLAIYVN"
     gene            complement(45734..47701)
                     /gene="treP"
                     /locus_tag="VQ540_000445"
     CDS             complement(45734..47701)
                     /gene="treP"
                     /locus_tag="VQ540_000445"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HET2544307.1"
                     /translation="MGKFEQEAKDLLQAIGGKENVTAVTHCATRMRFVLGNDKKANVK
                     AIESIPAVKGTFTNAGQFQVIIGNDVPIFYNDFTAVSGIEGVSKEAAKSAAKSNQNVV
                     QRVMTTLAEIFTPIIPALIVGGLILGFRNVLEGVHWSMLDGKTITESSQFWAGVNHFL
                     WLPGEAIFQFLPVGITWSVSRKMGTSQILGIVLGICLVSPQLLNAYAVASTPAADIAA
                     NWVWNFGYFTVNRIGYQAQVIPALLAGLSLSYLEIFWRKHIPEVISMIFVPFLSLIPA
                     LILAHTVLGPIGWTIGQGLSSVVLAGLTGPVKWLFGAIFGALYAPFVITGLHHMTNAI
                     DTQLIADAGGTALWPMIALSNIAQGSAVFAYYFMHRHDEREAQVSLPATISAYLGVTE
                     PALFGVNVKYIYPFVAGMTGSALAGMLSVTFNVTAASIGIGGLPGILSIQPQYMLPFA
                     GTMLVAIVVPMLLTFFFRKAGLFTKTEGDTNLQAEFVAQEEAEFVNHEPVELTSVEII
                     SPLTGQVKELSQATDPIFASGVMGQGLVIEPSQGELTSPVNGTVTVLFPTKHAIGIVS
                     DEGVELLIHIGMDTVGLDGKGFESLVVQGDHVTVGQQLIRFDMDVIKAAGLVTETPVI
                     ITNQDAYTATIPGTYPTTIQAGASLMVATRI"
     gene            47886..48596
                     /gene="treR"
                     /locus_tag="VQ540_000446"
     CDS             47886..48596
                     /gene="treR"
                     /locus_tag="VQ540_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HET2544308.1"
                     /translation="MKKYQQLFKQIQETIQNETYAVGDFLPSEHDLMEQYQVSRDTVR
                     KALSLLQEEGLIKKIRGQGSQVVKEETVNFPVSNLTSYQELVKELGLRSKTNVVSLDK
                     IIIDKKSSLITGFPEFRMVWKVVRQRVVDDLVSVLDTDYLDMELIPNLTRQIAEQSIY
                     SYIENGLKLLIDYAQKEITIDHSSDRDKILMDIGKDPYVVSIKSKVYLQDGRQFQFTE
                     SRHKLEKFRFVDFAKRKK"
     gene            complement(48629..49432)
                     /locus_tag="VQ540_000447"
     CDS             complement(48629..49432)
                     /locus_tag="VQ540_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000157668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET2544309.1"
                     /translation="MASLLTLENIHKTFEAGTVNENHVLKGLDLEVEEGDFISVIGGN
                     GAGKSTLMNILAGNLSVDEGDLLLAGKSIKHLSVRKRAKDIARVFQDPKMGTASRLTI
                     EENMAIALRRGQKRGLGWGVKEKDRIQFQEALKELNIGLENRLKVDTQYLSGGQRQAL
                     TLVMAALVKLKLLLLDEHTAALDPKTSQMVMDLTQKIVEYHQWTTLMITHDMNHAIEY
                     GNRLIMLYQGKIVVDVKGEEKKHLTVEDLMHLFQKNSGQSLVSDELVLG"
     gene            complement(49445..49873)
                     /locus_tag="VQ540_000448"
     CDS             complement(49445..49873)
                     /locus_tag="VQ540_000448"
                     /inference="COORDINATES: protein motif:HMM:NF014684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2544310.1"
                     /translation="MKTEIGLVLRSTGDNIPMSEANGVNVNTMKIVGYMISTGLIALC
                     GSLFAQNDGFSDVTSGTGTIVVGLSSEVLIHDLTIGGRLLSIGIGAIVYRLIILNIYE
                     IPNLDQNLVRLFNAILLALVLFAPALQKRLKIRGLKLRNE"
     gene            complement(49882..50322)
                     /locus_tag="VQ540_000449"
     CDS             complement(49882..50322)
                     /locus_tag="VQ540_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2544311.1"
                     /translation="MNFVLSSLSEGLLWSIMAIGVYLTFRILDIADMTAEGAFPMGAA
                     IVVSQIQAGANPWLATLLALLAGMVAGLISGMLHTKMKIPALLTGIVTLTGLYSINIK
                     IMGSVPNLSLGDSATVFKQLASLGLTNEGAVFSLSLVCLLLVWF"
     gene            complement(50367..51272)
                     /locus_tag="VQ540_000450"
                     /pseudo
     CDS             complement(50367..51272)
                     /locus_tag="VQ540_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000512061.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
BASE COUNT        15175 a        11736 c         9476 g        15288 t
ORIGIN      
        1 attaaaaggt taagtaattt ttccaaaata cagcactcat atagacagta tcatcaatta
       61 tagccattgg gattttttga ttgccaattc catgtatctc tacacatgtc ttcaatcgat
      121 tttgttgtcc tccaatttaa ttccttatat gctttgtctg catttgcata ataagttgca
      181 acgtctcctg aacgtcttgg aactatttta taaggaatag ggatcttatt aacactttca
      241 aatgtattta caagttgtaa tacactagtg ccttctcccg agcctaggtt atagatataa
      301 acatctgttt tttcagatac tttttctaaa gcttttatat gtcctattgc taaatctact
      361 acttgaatct tttatctcat ttttcccttt ttcaaataag ttatctactc tatgatcagt
      421 tatttccatt tcgtttacta acatgacgca gtcacctagc atcatatact ccaacttttt
      481 ttctgaaagt ttagcaaata ttggtaagcg ataatatagt atattgaaac tagaatagta
      541 cacctctact tctaaaacat tgttagaaat cgatttgact gtcctgattg atttgtccta
      601 ttattatttc attttactat actctgttaa ttcatatgag tttaaaccga tttcatcttt
      661 aacctcgagt aaagcagttt caaatatttg tttaagagtt tttgattctt tacaattaac
      721 cgacaaactt tctgataaaa tatgtacaac ttctgagact gaataaccta tctcctcttt
      781 agaattatat aaatctgtag ctccaccaat aatccaaaaa tactgatttt gtgaacctac
      841 aatatcctca ttttctacgg aacttccttg tatcgaacaa attttattta tctttaccat
      901 aatacttcaa cccttttagt gtcaaaagta aaccaattcc tgtcactgtt aagaatagtt
      961 ccataatctt gttcgaacca gtctttggta atttttgttt tacatctact atttctttag
     1021 atttattaat atgattttca gtttctctgc catctccaac tattttatag tttacttctt
     1081 ctgtcttatt atcttgttta ttgtcgatct tgtcattcat ttgtctatta tctttacttg
     1141 agttaaactc tccgttcttc tggttactat caattacatt atttgaatta gattgttttt
     1201 cctctttgtt tttttctttt tcgtttttat cacttaaatt atttgttaca attttgtaaa
     1261 gcccattctc cgttacaata ttgaaattac catcgctatc acgtataaca gattctttcc
     1321 catttgcatt agatttgatg aatgatatat acttaccgga taaattataa aattggttat
     1381 ttaaaacggt tattttaccc tttgaatcct caataacaat tccttcttta ccaccgaata
     1441 tactattctc tgagactact aaattatcac taactcgtaa taattcaata tttggttgtt
     1501 ctgtttcctt agaattatta ttaattacat tttttgttac agtaatatct gatacttttc
     1561 ctaaatattc tgcactatct tttgcaactc gtatcgcttt tgttttagga tcggcaatat
     1621 taaatatatt ttcggcgata accacctgtt tatttaaatc taataggtct ttagtgtttt
     1681 tatagctata agcatttact aaagctgctc cgctttctcg ataatgtaca ctctctcctt
     1741 taactttctt atcaaagcga tttcctttga ttaatacatc agtgaatcct gtaaaacgta
     1801 cacctgcata catcatgtta tcaaaatgat tatttaaaat tttaatatta gaggggttct
     1861 gtgtcgacaa tgtttgatag tgtgtgccaa ttgctgttac taattcccca gatttatcac
     1921 ttttgccaaa ataggaattt tgaatagtca cattttcaga ttttttccca tcatcattca
     1981 aggcataagg aaaacctttt ctagttaatg gttcaatctg aatgctctcc ttacttatga
     2041 tttgcccatc cttcatcgtt ttgggtaagg cttgcccaag aaaacgagaa ttatcaacta
     2101 atacattttt cgaacctgca atttgaatag catgcccttg ataactatcc ttgaatgtta
     2161 cattttttat agttacgtta tttgaattcc caatagcaaa tgcacctgaa gaatttataa
     2221 gtggtagatt ttttgcttta gttccttctt cattcaaagc accgttcata tcaatcgtac
     2281 caccagaata actaatatct tctgttgggc cccattctac ttgcgcacca tcatccgtaa
     2341 ataaacctgt cataaaaaca atggaagggt gattcttaat atttatacca tttagaattg
     2401 tagctttctc attcaattct aagtgtgtat gactttttaa aaaaacaatt tcttttacta
     2461 aataagttcc ttcaggaaaa tatacatttc ctccacctag cccttgagct gcagcatcta
     2521 ttgcatcttg aattgcttgt cgatcatcat gaatcccatc acctaccgca ccataatctt
     2581 ttacacttaa agcagtatct tcaaattctt ttttgataat tctgtcactt ataacatctt
     2641 ccttataact cttattttca ttagtagata ttactgtaga ttcaactgtt ctgttgtcta
     2701 attgtgaatt ggaacgaata gtaccattag agctgatact attaacactt aacgaattat
     2761 ctaaaccatt agtggttgaa ttagaggcaa tcatttcagc agaacgattt tgattaacag
     2821 ttggtgaatt atctaaatca ttagtgattg cattagaaga ctcttttgta gccatcggtg
     2881 aagaactagt aacaacttca tccgataaaa taccttggct tcccaaaatt gaaattgcca
     2941 atagtaccga gcaagtcccc acctttaatt tacgaatact gaatacctca ttaggaacaa
     3001 aatatttcat cagaacctcc aattttttta ctatttttaa caattgatta ttacttttct
     3061 taaaatagat agaatgacac cgctgtcatt atctttatca tatattttcc aaattgaatt
     3121 gtcaaggaat aacacaagaa aatattaaaa tttatactct tcggaaatct cttcaaacta
     3181 ggtcagtgcc gccttgccct aagtctaggt tactgacttg gtcagttcta tagtagactg
     3241 aaactataat agtacacctc tacttctaaa acattgttag aaatcgattt gactgtcccg
     3301 atcgatttgt cctattctta tttcatttta ttatatctac aacctcaaag cagggttttg
     3361 agctatctat ggccaacttc ctagtttgct ctttagcctt ccattcaaaa gtgatgctat
     3421 ctttcttagc ttgaatataa aatatcccat ttactatatt taaatttgtt gatatgttgt
     3481 aaattataaa tgaaagaaca aatatcttgt catacaagca ttcgccaggg atatttacat
     3541 gaatatcgct catatggcgg attgaaacta aaacactaca atatatttct taaatagacc
     3601 ttctataaaa gctagattta acctcgataa aaatagatgc agtgcttcta aaatactgga
     3661 atagggcata taggtaatcg tagacaagtg ttttatagat tgtctcgcgg gagatctaat
     3721 gatgtatagc aagcatcact aaacatatag aatatttgtg ttattataat gtcaatatgc
     3781 tataaattct atcatgcaaa agaatgacta gaacatgaaa gacaggcaca aaactttgaa
     3841 caatattctg aaaacaaaaa aagacgcgag tttccacaat ctcactcatg gaaactcacg
     3901 tctttcaaaa aatagggtga attaaaaact agaacaagac actagatttt ctaaatgatg
     3961 tctagtaagg attctaaatg ctacaccaaa ttgctcacat cttatttcaa accacgggac
     4021 tcccacaaga aaggaaaatc ctataaaaat tctctctctg aggagagaga ggcctcaact
     4081 acaggtgtaa actattatca attgaaaaca acagttttta cactcaatta gactttttag
     4141 ggacaggatc actttcgctt gactgtagtt tgtcattttt ttgataaagt tagcactttt
     4201 tcagaaactg ttttgaaagt ctcaatgata tagtctactt cttcatcgct taatttagta
     4261 tgaagaggga gggtaatttc attctcaaag aaggcatagg ccttaggata gttcgtcata
     4321 tcaaatccaa gattcttata ggctgtcaag agaggaagcg gtttgtagtg aacattactt
     4381 gcaattcctg ctttagccaa ttcttggatg atgaggttgc gttcttctag gcttgctcct
     4441 tctacacggg tgatgtagag gtggcgtgaa gattcgacag tttcagtctt gtgtgccaaa
     4501 ggatggatgc gagaacctgc aaaaccacta tcatagcggt ccacaatgtc cttacggcgt
     4561 tgcaacaaac ttggatagcg gtccaattgt accaaaccaa gtgaagccat gatatcggtc
     4621 atgttgcact tataggctgg tgtaacgata tcgtattccc atgaccccag ttgcatcttg
     4681 gcaagagcat ccttagtttg cccgtgaagg gaaaggattt ggaattcctt gtacatctct
     4741 tcgtcatcaa tcactggatt ggctttccaa gtcgcacttc caccttctgc cgttgtaaag
     4801 ttcttaacgg catggaatga gaaggaagta aagtcagcga tagaaccaga aggttgtcct
     4861 ttataagtag atcccaaagc gtgggcacta tcagagacaa tgacaatacg gttaaaggcc
     4921 ttttgccact tgcttgaagc ggtaaagaag tcacgttttt tctccacgac ttggaacaaa
     4981 cggtcataat cgcaaacaat ccctgcgagc tctactggga taatcacctt agttttctca
     5041 gtgatagctt gctcaagcag gtcatagtcc atctcaaacg tatctgcttg gatatccacc
     5101 atgacagggg ttgctcccac gtgcgtaatg acactacatg aagccgtata ggttatggct
     5161 ggaacgatga cttcatcacc aggtcccact tcaaaaacgc gtaaaatcaa ctccagagcg
     5221 gctgtcgcag agttgagaca aacagtctta ggtgtctgtg tgtaaagaga caagcggcgc
     5281 tccagttctt ttgttttagg acctgttgtg atccaaccag aacgcagggt atccgctact
     5341 tcagcaattt ctgcttctgt gatatcaggc ggtgaaaatg gaatattgta atttggcatt
     5401 gatttgctcc ttttatctgt actcattctc ttatgactac tttattttag taccttaaac
     5461 acggtttgaa acatgatttt gatgtcccca aagaaactaa actctcggag ataggcgagg
     5521 ttatagcgca tcttttcagg aagaacatgc tccacatagg cctgatcaac tgacagacct
     5581 ttctctgtca tttgactgat gatggtgtcc tcatccttgt agttgatgct ggctggagag
     5641 gtaattcctg cttgcaagag caaggttgcc atcatttcag tgctatactg ctctgtataa
     5701 cgtggcactt caggtcgtgt accgacaaag gacatctcac ctttaaggac attgaccaac
     5761 tgaggcagtt cgtccaaacg gacacgtcgg atgaaatttc caaccttggt aatacggcta
     5821 tcgttagcag aagtcaccag atttcctttt ttatccgcat ccgtcaccat ggtacggaac
     5881 ttccaaatct tgaaccgacg gttgtactgg gtcacacgct cttgcttgta aatcactggc
     5941 cccttgctat ccaacttgat ccaaatgctc aagatgagaa agatgggaga ggtcagaacc
     6001 agtaagacca aggccaaaac ccagtccaag caacgcttga aaatcagcga acccttcctt
     6061 ttagagacaa gctggtagta agactcaacc tcgcttgatt tcatttccac aggcaagtct
     6121 tcccatttca gcatgctgtt ctcctttgtt tttattatac tatttgtcaa cactttttgt
     6181 caacactttt cattatacca caaaatggaa aaggcggtga aaaaaatctg taatttgaag
     6241 gatttccttc tagtactcaa tgaaaatcaa agtacagctt tgagattgca gataaagctg
     6301 acatggttta aagagatttt caaagagtat aggccatggc ccctgcctgc aaactataca
     6361 tcttgtgata ggttcctccc agagccaaga gttcctcatg ggttccactc tcgataatgc
     6421 gtcccttatc caagacatag atgcagttgg cgtcttgaat agtagaaagg cggtgagcta
     6481 tagcaatagt tgttcggccc tgtctcatct tcgccagaga agcttgaacc aagctttctg
     6541 tttcagagtc aatattggct gtcgcttcat ccaaaatcag gattttaggc tggctggcga
     6601 ctgttctagc aaaggcaaga agctggcgtt gcccagtaga gaagctcgaa ccacgctcgg
     6661 aaacagggga gtcgtacccc tgaggaagtt cttgaataaa ggaatctgca tccacaaagg
     6721 ctgccgcagc ctgaacctgc tcatcactga tttcttggta catggcgata ttggacttaa
     6781 tagttccatg atagaggaag ggttcctgca agaccaaacc gatgtttttt ctcagctctt
     6841 cttgactgaa atccctgata tccacatcat ccaagagaac tctccctgac tggaattcat
     6901 aaaagcgcat gaggacattg ataatagacg atttccctga acctgtatga cctacaaagg
     6961 caatggtttc acccttatta acagagaaag aaatgtcatc cagaatcgga tgtttaccgt
     7021 catatgagaa acacacatgt tcaaagcgga tattgccttc ttggactttg gcttgcccat
     7081 tttcttgaag aggttcatag gtcctctcgt ctaccagggc aaagacacga cctgcagaaa
     7141 ccatagacgt ttgcagtgtt gaaaagtttt gcgtcacctc aatcaaaggg tcaaagaggc
     7201 ggttgatgta ctggataaaa gcatacatgg tcccggccgt tatcccgata gaaagaccac
     7261 gatagccaaa ataggccatc aagacagcat aacctagaag tttcaacaaa ctcatggcag
     7321 gtctcaaaaa gagggcatcc aaggctacag aacggttggc atagaccaag tgctcttggt
     7381 tgatttcatc aaattctgcc tgcaggcgct tctcttgatt aaaggcctgg attattctga
     7441 ttccctcgat gttttcagcc agcttgctat tgatatctga caagagactt ctggttttct
     7501 caatgatttt cactgatttt ttccgataga gattgaccaa aaggaaaatc aaggggagaa
     7561 agagcaagac taatgctgtc aaacgaaaat ccaataccaa catggtataa agggttgtca
     7621 gaaagatgaa aactgctgag ataaagctag ataaaatccc agaaaacata tcactaatcg
     7681 tctcggtatc gttggtcaaa cgagaaacga tagaacctgc tggcgtcttg tcaaagtaag
     7741 acatgcccag tttctccata ttggcaaagg catcccgacg aatatcccta acaatactgt
     7801 aagacacgcg cgcaaagaga agattgccga catactgaac tacagtttgt aggatgtaga
     7861 gaccatagta gaccagcaaa acggtaacgg ctagttggtt aagattgctg agatactggt
     7921 cgataaagtg ggaagccacg aggggtatga cacttttaat gaccgtcgtc gctaggagaa
     7981 aactgagtgc caaaaaggtc aggagtctat aaggcttgag ataagacatc aagcgcttca
     8041 atacagccca ttgttcttgt ttattctgca tcttcttctc ctttcatttc taactgctga
     8101 gactggtagg tttgggcata ccagccatcc atcgctagca agtcttcgtg cctgcctcgt
     8161 tcgataattt gaccattttg tagaactaaa ataaaatctg catggacaac agcactgagg
     8221 cgatgggcag ttataatggt tgtcttgtcc tttcgcgtct ccttgagatt gtcgataatc
     8281 gcatactctg tcttggcatc tacggcggat aaggaatcat ccaaaatcaa gatatcaggg
     8341 tttaaaatca tagcccgact catagccaac cgttgctttt gaccaccaga aagactgact
     8401 cctttttcac caatcagcgt atcaaatcct tgaggcatgt ctacaatatc ttggtaaact
     8461 cgggctagct tagtagcttc ctcaacctct gaaaggggca agttaggatt gccaaagcgg
     8521 atattgtcta ggattgaagt cgcaaagaga aactggtcct gaggaacata gcccatgaga
     8581 ctgcgaagtt ctgtcaaacg atagtcccga atatcgtgac cgtttagata aatggcaccc
     8641 ttatccacat cgtattcacg caagaggagc ttgattaagg acgttttccc agagcctgtc
     8701 tgcccaacca agcccagtgt ttgccctttt gccaaactaa agtgaatatc cgtcagtgtt
     8761 tcctcatttt caaaagcaaa gctgtcaatg gcatactcca aacgcccatt ttcaatacca
     8821 tccagaggaa actcagggtc ttgtacagga gattcctgag acaaaagatt ttcaatccgc
     8881 tggtaagaaa ccttccctcg ctgagtagta ttaaagagga agccgatggc cataagaggc
     8941 cagaccagca tatccaaata gctgataaag gtgactagat taccaactgt aatctgccct
     9001 tcctgaacca tcaaggagcc aaccaaaagc gttaaaacat aggacgaacc aacaaacaag
     9061 agaaccatag ggtcaaagag actatcatat ttcatggttt gcaggttctt ttggaaggtt
     9121 aattcattga ctgcctgaaa agacttcaac tcgtctgcct gataaccgaa agacttggtc
     9181 actttgatac ctgatacgga ctcctgtacc ttgttattga gttcagaaaa agcagcttgg
     9241 gattcgccaa aggccttatg agtctttctc cctaggcgac tagtcgcata ggccatgaaa
     9301 ggtaggggga gaatggcaac aagagtcatc tgccatgaga tgctaaagag catggtcaac
     9361 aaagtcacca gagccgtgat agaggcatcc accgcagaca tgacaccgcc acctgctaaa
     9421 cgagtcaagg cattgatatc attggttgcg tgtgccatca gatcacccgt ccgataggtt
     9481 tgataaaagg ctggcgacat ttttgtgaaa tgcttaaaca agcgagaccg catgatctgt
     9541 cccaagcaat aagaggtccc aaggatatac atacgccaca catagcgcaa atagtacata
     9601 ccaaaggctg caagtagcaa gtaaaatagg ctaagaagga ggtcctgctg ggttaattgc
     9661 cccgatgtga tggcatcaat gactcgcccc ataaccatag gaggaatgag attgagaacg
     9721 gaaaccaaga ccagggccac aatcccgact agataacggt gtttttctaa cttgaaaaac
     9781 caccagagtt tttgaataat ggacataaaa tccctttctg attgcaaatg gaaacctgag
     9841 gccaatactc aatgaaaatc aaagagcaaa ctaggaaact agccgcaggc tgctcaaagc
     9901 actgctttga ggttgtagat agaactgacg aagtcagtaa cctacatacg gcaaggcgac
     9961 gttgacgcgg tttgaagaga ttttcgaaga gtacaagacc ccaggttttt cttattcata
    10021 agttacgact gtaacagcac ccttgtcata ttcagcaata aagatattgg ctacattgtc
    10081 atgcccttgt ttgctgaggt tatcaagcaa ccactcttcg ctacgaccaa tcgattccaa
    10141 gacgtctact tgaatcacac cgtcagtcac aactggatac ttaggatttt catctcccat
    10201 ttgcacaacg atgagttgcc cattttgctc ttgcacagct cgtttgactt gcttcatctg
    10261 gaaaatccct tggctacgaa gtttgagggc tacatccgat gcagacaaac caactgaacg
    10321 acaggcttat gggtcaatat tcccattttt gataaggaga gttggcttac catcaatcaa
    10381 acgtttcaca aagtgaacat tgttgttgag ctatttgaga gtcaagatca gtttgattaa
    10441 aatttcgata taattaagtg tcatttgttc acatccacca gttcaattgc gtctgtctta
    10501 tacaattcga ctttctctaa caggtacttg tctggctcac ttccgtttag ggcacgataa
    10561 tagcgatctc ccaccttgat aagtgcgcca tctgtgtttg tggaagtatt aacatggact
    10621 tctgacttgt ctactcccaa atctttggaa acaacctcga tgaaatgaag tgaagtttga
    10681 aatttattgt tagaaacttg attgttttga taagtcgtga tgctgaccaa aagcatagct
    10741 aaataaggcc agagctgaaa tcatgaccaa ctcacgaaat ttggttcctt ttttatcatg
    10801 gtatgccttg aaagcaaaaa aaactgtcac agctaataga acaatcccaa agccaaccat
    10861 gataccattt tgctgaccga tttggctgag tacatagtca taagagtaga atttcatgta
    10921 ttttcactcc ctttcataaa atcattctta attataaacg aaagagagta atttttcaaa
    10981 ccatacgttg gggaaataga tctttttttg gtataataaa atctataatc tgaatgaaaa
    11041 aggtaacttt atgaaactta tctcatggaa tattgattcc ctaaacgctg ccctaactag
    11101 tgactcagct cgtgccaaat tgtcccaaga agtcctacaa accttggtcg ctgaaaatgc
    11161 tgatatcatt gctatccaag aaaccaagct ttctgccaaa ggacctacaa agaaacacgt
    11221 ggaaatttta gaagaactct tcccaggcta cgaaaacacg tggcgctctt cccaagagcc
    11281 tgcccgtaaa ggctatgctg gaaccatgtt cctttataag aaagaactta cacccactat
    11341 cagcttccca gaaatcggtg ccccttctac catggacttg gaaggccgta tcatcactct
    11401 agaatttgat gcatttttcg taacccaagt ttacactcca aacgctggtg acggtctcaa
    11461 acgcttggaa gaacgccaag tctgggatgt caaatatgcg gagtatttgg ctgaactaga
    11521 caaagaaaaa ccagtccttg cgaccggtga ctacaacgta gcccacaatg aaatcgacct
    11581 tgcaaatcct gctagcaacc gccgttcacc tggatttact gacgaggaac gtgctggatt
    11641 taccaaccta ttggcaactg gatttactga taccttccgc catgttcatg gcgatgttcc
    11701 tgaacgctac acttggtggg cacaacgcag caaaacttct aaaatcaaca atacaggctg
    11761 gagaatcgac tactggctca caagtaaccg tatcgctgac aaggtcacta aatctgatat
    11821 gattgactca ggtgctcgcc aagaccatac accgattgtc ttggaaattg acttgtaagg
    11881 attttctata tggactacaa tgcggtcatt cccgagtttc ttgtatcgaa tatcgaacag
    11941 tcccggtcct tctactgtgg tttactgggt tttaggattg aataccaacg ttcagaagaa
    12001 aactttctct ttctcttgaa gagtgtcaac taatgttaga ggagggaaca aaggatcaac
    12061 tagctgaact gacctacccc tttggtcgtg gagtcaatct ctcctttggc ataaaggatg
    12121 ttccaaaact ctatcaaaaa gtgatggagg caaactatcc tatttatcgt cccttgacca
    12181 aaagaaagtt tcgtgtcagt gatccctata tctatcctca taaatttgca gttttggatc
    12241 cagatggcta ttttttaaga tttagcgagt agaataataa aaattgggaa aagtctttaa
    12301 aagttagaaa aaggcatatt gtcaggtgtc taaaaacttg atagtatgcc ttttatgatg
    12361 gaaaaatctt ctaatactct tcgaaaatct cttcaagcca cgtcaacgtc gccttaccgt
    12421 aggtatataa tactgactct gtcaattcta tccacaacct caaaacagtg ttttgaggtt
    12481 gtggatagct tcctagtttg ctctttgatt ttcatttagt ataaatgtta gcttacaatg
    12541 gagtttttgt tcaccctctc ttctgtttgt tcgtttttta aaccaaaaca ctaacaaaat
    12601 agttgatttc taaagttatt tagtgtaaaa taaaaacatt ggctcaagcc tatttaaaat
    12661 tgaatatcgt tttacttgtt tatgtcgtga attggcacga cgtttctaca aggtgccgga
    12721 acacctaaca ataagtaagt cagcagtgag atatggccgt ttttgccatg cctatttggg
    12781 ggacttactt agagattaag taggtctttt ttgaatattt ttaatatttc ccttaattag
    12841 tgcggacggg aggtgaaatt atcctgtgaa taatttcagg aatccaggga atttcatccc
    12901 taatttttga gcccctagct ctttcatttc taggcttagg ctaaaatagt tccccgaact
    12961 attttactct caaaaatccc gtcatagaca ataacaagat tattgtctat gataccacta
    13021 caacgggaaa tatttgataa gactcgcttc gctcgtaata gttttatcaa atatatagca
    13081 ttagcaaaag ggatcactat agaaacattt aaacaacaag taaattaact tttagacttt
    13141 aggaggtctt atgaaattat tagaagagcg catcctcaag gatgggcata tcttgggtga
    13201 taacatcctc aaggtagatt cctttttaac ccaccaagtt gactttagct tgatgcgaga
    13261 gattggtaag gtttttgcgg aaaaatttgc tgctgccggc attaccaagg tcgtaaccat
    13321 tgaagcgtcg ggtattgccc cagccgtttt tacagctgaa gccttaaacg ttcccatgat
    13381 tttcgccaaa aaagctaaga acatcaccat gaacgaaggc atcttaactg ctcaagtcta
    13441 ctcctttacc aagcaggtga ccagcaccgt ttctatcgct ggaaaattcc tctcaccaga
    13501 ggacaaggtt ttgattatcg acgatttcct tgctaatggc caagctgcta aaggcttgat
    13561 tcaaatcatc gaacaggccg gtgccacagt ccaagctatc ggtatcgtga ttgagaaatc
    13621 cttccaagat ggccgtgatt tgcttgaaaa agcaggctac cctgtcctat cacttgctcg
    13681 tttggatcgt tttgaaaatg gtcaggtcgt atttaaggag gcagatctct aatgcaaact
    13741 caagaaaaac actcgcaagc agccgttctt ggcttgcagc acttactagc catgtactca
    13801 ggatctatcc tggttcccat catgattgcg acagcccttg gctattcagc tgagcagttg
    13861 acctacctga tttctacaga tatcttcatg tgtggggtgg caaccttcct ccaactccaa
    13921 ctcaacaaat actttgggat tggactccca gtcgttcttg gagttgcatt ccagtcggtc
    13981 gctcccttga ttatgattgg gcaaagccat ggtagtggcg ctatgtttgg tgcccttatc
    14041 gcatctggga tttacgtggt tcttgtttca ggcatcttct caaaagtggc caatctcttc
    14101 ccctctatcg taacaggatc tgttattacc acgattggtt taaccttgat ccctgtcgct
    14161 attggaaata tgggaaataa cgttccagag ccaactggtc aaagtctctt gctttcagct
    14221 attactgttc tgattatcct cttgatcaac atctttacca aaggatttat caagtctatc
    14281 tctattttga ttggtctggt tgttggaact gccattgctg ctactatggg cttggtggac
    14341 ttctctcctg ttgcggtagc tccacttgtc catgtcccaa ctccactcta ctttgggatg
    14401 ccaacctttg aaatctcatc tattgtcatg atgtgtatca tcgcaacggt gtctatggtt
    14461 gagtcaactg gtgtttatct agccttgtct gatatcacaa aagatccaat cgacagcacg
    14521 cgccttcgca acggttaccg cgcagaaggt ttggccgtac ttctcggagg aatctttaac
    14581 accttccctt acaccggatt ttcacaaaac gttggtttgg ttaaattgtc aggcatcaaa
    14641 aaacgcctgc caatctacta cgcagctggt ttcctggttc tccttggact gcttcctaag
    14701 tttggtgccc ttgcccaaat cattccaagc tccgtcctcg gcggtgccat gctggtgatg
    14761 tttggttttg tatctattca agggatgcaa atcctagccc gagttgactt tgctaacaat
    14821 gaacacaact tccttatcgc agctgtttca atcgctgcag gtgtcggtct caacaacagt
    14881 aatctctttg tcagcatgcc gacagccttc caaatgttct tctcaaacgg aatcgtcgta
    14941 gccagcctac tcgccattgt cctcaatgcc gtattaaatc ataaaaagaa ataagaaaaa
    15001 gaggtgcgag cctctttttt gtttatcaca aattgattat aaatacaatc aatcccaatt
    15061 cccatctaat tgaattggac ctatttcaaa ttctttaaaa tattatgttc caaatcgtta
    15121 atattatata agaatggtaa aatatcaaat gtttctcgta aattattctt agccttatac
    15181 caaccttgtc catcagtaat ccacataaac tcaacattag gaatagcttt aatttcttca
    15241 gcaatcattt tgtaagatct agccgtctca tttaattttg aaccacttcc tgaataaaaa
    15301 ttaacctcaa tcagataaag cacttgttca ttttttatga caaaatcaaa acgtttcaca
    15361 gtattcccat cattcgtaat agcagataaa tcgacagaaa aaatttcctc tatttcattt
    15421 tgttcaatct ctttaaataa attctctcct aaaatatacc cttcagcttc aagataactt
    15481 tgaacaatat tttccatcgc atctccagtc cgatttttgc gcccattagt atccatacca
    15541 acctcaacac ctgtaacgta gtcaactaaa tttgatacta aatgattttg caataaatca
    15601 aatatacctg atttttccaa aaacatagta tattcttcaa tactatagtt tcgtttacta
    15661 aaatcaaaat agaaatcttt tatcggatcc ttaacaataa tcgtatctct caaacgttta
    15721 gcaataagta gaggcacaac tttcaaaatt tctggataat tttgatataa gtctaaaaaa
    15781 tcctcttgta tatttttact accaataaga ctattcataa tatttagagc aacttttata
    15841 ctagatacat ttttataaac cttgggaaaa tctgtataat aagtccagtc agctactgtg
    15901 tcggtcatcg ttgacaacca ctcatcaaaa tttctagttt gtttcatttt ctgcctccaa
    15961 cctcttcctt gcaattttta aatattcttt ttcagcatcg atacctataa atcttctacc
    16021 taaccgcttc gcaacaacac ccgtagtgcc actaccaaca aatgggtcta gaatatagtc
    16081 accctcttta gtagaggcta aaataatgcg ttctaacaaa tactctggtt tttgagttgg
    16141 atgtttccca gcccattttt caactttctt tgttaaagaa cccgtccaga catctttcat
    16201 ttgttttcca tcattcaatt ctttcattaa atcataattg tagtaatgac gagctttttt
    16261 atcatttttt ctggcccata aaatggtttc agtagaatgg gtaaaataac gacaagataa
    16321 attgggggca gggtttgttt tctgccaagt aatattattc agaattttaa aaccttcttg
    16381 ttctaatgcc attccaactg agtatatgtt gtgcaaacta cctgaaatcc ataccgtccc
    16441 attaggcttc agaacttctt ttgctaggcg aatccattta cgattaaact catgtttttc
    16501 ttcgaatgaa gaaattttat cccaatctcc tttatcaaca gaaacaactt gtcccccaga
    16561 attagatatt ccaccattac ttaaaaaata aggtggatca gcaaaaatca tatccatact
    16621 ttctggtttc atttttgata agaacttgaa cgtatctgaa tgaacaagaa tcatcttatt
    16681 tttattgtag tatggttttg tcataagaac acctccatac ttatattcgt tatttttcat
    16741 aatttgtgac tataatttca gaaatttttc ctcgacttga agattttgct ccattagttc
    16801 gggtagcttc aacataatgt atattaaaat ccttatacaa ctcctctact aaagcactag
    16861 aagaatttga taacataaca taagctcctg tatcactcaa tctcttaaag gcatctctta
    16921 atcttacttg atctgcaaaa gagaatccct catgagtata agacgtaaat gcactcgtct
    16981 cagacaatgg aatatatgga gggtcaaaat acacaaaatc tcctgttcga acatctacaa
    17041 ttgccttttc aaaatctccc actttaattt ctagttgatt gttatttaga taaactgaaa
    17101 tagcagatat caattcctca tcaacaattt taggattctt ataacgtcca tatggaacat
    17161 taaattggtt cttagaattc acacgatata gaccattaaa gttcactctc aacatatata
    17221 gaatacgtgc agctctttgt acttcggaca tcatatctat tctttcatca cgatctgcag
    17281 aacgtaaatc taaataatat tcttttgaat tatattcctg atgaactttc aaaatttcaa
    17341 tcaattcttg aggattgtcc ttaatttgtt gatagcaatt tattagttca gcgttaaaat
    17401 cattaataac tgcatcttta ggagccaaat caaaaaataa agctccacct ccaacaaaag
    17461 gttcgaaata cctgttatag gttttaggca ttaattctct aataacaggc aataattgtc
    17521 ttttaccacc tgtccatttc gtgaacggtt gtaaagtaac tttctttatt tcttttatct
    17581 tcatgctttt aattatacca tagaaattaa aacacaactc ttgtattttc taccacatta
    17641 ctaaattttc tattttagaa ttaaatcata tcaatataaa aaaatgagta aggcaaatct
    17701 tataaattcc aaaattcacc tcactctatt aaattactct ttatatcctt acccgtcttt
    17761 cctcagacct ttggcctgtg acaaacatag taaaggttgc tttgcagaca tttctgccct
    17821 cttgattggt gatatccaca tccatcacac aggttgtacg accttgatgg acacattctc
    17881 ctttaatggt caatacatcg tcgagttttc ctgccttaag gtagttgata gaggattgga
    17941 gtgtcacccc atcaagtccc agcgagataa ccaccaaacc actgatttgg tcacatagtg
    18001 tgaatagata gccaccatgg gcattgccat agtagttgag cgacgagttc actactttgg
    18061 tcgtcaccac aacgtgacca tctctcattt tttcaatttc gtaattttca aaggcagata
    18121 tagcgtcaaa atgaaagtct ttcatcgttt cctcctgata tttcaaatga cactatgata
    18181 ctacttttta taggactgtg caaggagaaa gctcctagtc tagtaaaatt ccgacatgtt
    18241 ccacaaagcg cataaaggct gtctgccctt gttctgtctg cttgtagact cctgcatcct
    18301 caagtacacg cgcaaagata gcacccacag agtccttgac gattgcaagg gctttttctt
    18361 tatccgttag gtctggatgt tgggatttga gttggtctgc ccactcctga tgataatcgg
    18421 caactgtaac agcttctcct acaagatagc tagcgacttg ctctacttct tctttcagac
    18481 gtggtggcaa gattgccaag cccatgacct caatcaagcc gatattttcc ttcttgatat
    18541 gttggacatc cttgtgggga tgatagatgc catcaggatg atctgctgaa gtctgattgt
    18601 ctcgcaagac caagtccaac tcaaactgtc catcacgctt acgcgctatt ggtgtgatgg
    18661 tgtgatgcgg tgtcccgtct gtctctgcta aaatctgcac actagaatct gaatactgac
    18721 gccattcctg gaaaatctta tcagctaagt taatcaaatc ctctttggaa tccgaagtca
    18781 agcgtaggac agacattggc cacttgataa ttccagcctt gacctgctca aaaccagcaa
    18841 atcggaaggt cttttgcaag ggagccaatt ccataggaaa tacgtgacgg cctccctgat
    18901 aatgatcatg agttagaata gagcccccca caatcggcag gtcggcatta gatccagcaa
    18961 aatatcctgg aaactgctct acgatagcca acagacgttc aaaactctga cgactaatgg
    19021 ccatgggacg atgctggcca tctaaaaaga tacaatgctc attaaagtaa gcatagggcg
    19081 aatactggaa accccattcc tgaccaacca tttcaaaacg gataatccgg tggttgctgc
    19141 gagctgggtg gttgacccga ccatggtaac cctcattctc taaacaaagt tgacactgag
    19201 gataattact agcttgcacc aacttggcta ccgcaatctc tttcggatcc ttttcaggct
    19261 tagagagatt gatggtaatt tcaagttctc cataatcaga tggaacacga taaacgatat
    19321 ttttagcaat ggccttgagt ttgatgtagt catttttctg actgagttga taaaaatcct
    19381 ctatcgcttg ctcaggagag taggcatagg cttcccagaa gtcacgattg acctgactcg
    19441 gacaaggagt caccaagtcc atcaattcag taccaaggat ttcacgcgca gtctgactat
    19501 cctcaatcgt ctctaatcga acggcttcct caactagctg gtccttgagg tcaatcaatt
    19561 tatccagatt ggtctcaact tccaaaacac cttctcccac tcgtgccaaa acacgattgg
    19621 tcaggtagat tcgatccatt tcctcaaatg aactttcaga aatgacatgt gttacaaatt
    19681 tatctactaa ggtcactata gagcctcctt ttgactagtc aaggacgcga gtgccacctg
    19741 caacttcagc gatatagaag cttggagcgt atccaactac ttcctcgtag tgtttgccta
    19801 cagcttcctt aaaggcctca acagtatctt tttgaaccaa ggcaatggca cagccaccaa
    19861 aaccagcccc tgtcatacga gcaccgagaa ctccttcttg tgcccaagct gtgtgaacaa
    19921 gagtatccaa ttccaaacca gttacttcat aatcatgctc cagagaaacg tgtgacgcat
    19981 tcatcaaacg accaaatgtt tccaaatcac ctgcttgaag ggctgcttga gctttaaggg
    20041 tacgttggtt ttcaaacaca gcatggcgag cacgtttcaa acgattttca tctttaatca
    20101 gatagctata ttggtcaacg gcccactcgt ccaattcacc cagggtctga atatccaagg
    20161 caacttgcaa ttcttccact gctttttcac actcagcacg acgttcattg tatttagagt
    20221 ccgccaattc acggcgtttg ttggtgttca tgataacaac gacattgtcc ttcaaatcaa
    20281 gtggcaccaa gtcgtattct aaagtattgg tatctaagta aatagcacgt tggtcagccc
    20341 ccataccaat agcaaattgg tccatgatac cagagttgac tccgataaag ttattttctg
    20401 tttgttttcc gattttaacc aaatcgagac gctctagttt taaatcaaag agatgctctg
    20461 ccacgactcc tgtcaagagc tccaaggatg ctgaagaaga caaaccagca ccatttggga
    20521 tattcccata aacataaaaa tcaaaacctt tgtcaatcac gtgcccagct tcttgcaaga
    20581 aatgaaggac accttttgga taattggtcc agttgtgctc tttttcaaac ttgaggtcag
    20641 cgagaggcac ttcgataatg cccttgtcct caaagttagc tgagtagaaa cgcaagactt
    20701 ggtcgtcacg cttacgagct gcaccgtaag ttcccaagga aatagcagca ggaaaaacgt
    20761 gcccaccgtt gtagtctgtg tgttcaccaa tcaaattaat gcggcctggt gaaaagaagg
    20821 tttggtctgc ttcttgacca aaaacagcaa gaaagtcttt gcgaagggct tcagtagtaa
    20881 gatgttgtgc catatgaatt ctcctttgac tgtccgttaa gccaccttaa cgtataatcg
    20941 ttttctttct attgtatcca aggaattttc caagatcaat cctttttact aaaattttag
    21001 taaaatatca gtaaaaagaa gaaaaacatg atatactaac ctaatcaagg aggatttatg
    21061 gctaccttaa aagacattgc acagctagcc tctgtctcta tcgcgaccgt atcccgcgtc
    21121 ctcaatcgcg accagagcct atctgttaca gaagaaacca gacaccgtat tttaaccgtt
    21181 gctgaagagc tgggctacac caagcacctc aagacaggcg agtcccacaa acccaagcaa
    21241 aagattgcca ttatccaatg ggtcagcgaa caaggggagc tggacgacct ctactactac
    21301 cagattcgcc taggaataga aaaaagagcc caagagttgg actatgatat cttgcgctat
    21361 tttaatgacc atccttttac cttaagcgag gaagtgattg ggattctctg cattggaaaa
    21421 tttagccgag ctcagatttc tgcctttgaa gaataccaaa aacccctggt ctttctagac
    21481 agtgatacac tttctctggg gcatacttgt attattacgg atttttacac tgccatgaaa
    21541 caggttgtcg attatttcct cagccaagga atggaccgta tcgggattct aacaggcctt
    21601 gaagaaacaa ctgaccaaga agaaatcatt caggataagc ggctggaaaa tttcagaaac
    21661 tacagtcaag caaaaggaat ctatcatgat gaactggtct ttcaaggaaa ctttactgcc
    21721 cagtctggct atgacttgat gaaggaagcc attcagaact tgggagacca actcccacca
    21781 gcatttttcg cagccagcga tagtttagct atcggtgccc ttcgtgccct ccaagaagct
    21841 ggaatcagcc taccagaccg tgtcagcctc atttccttta acgacaccag cctgaccaag
    21901 caggtttatc ctcccctctc cagcatcaca gtttatactg aagaaatggg gcgagcaggt
    21961 atggatattc ttaacaagga agtcctccac gatcgcaaaa ttcctagcct gaccatgctg
    22021 ggaaccagac tgacattaag agaaagtacc ctaaatcaag aataggataa cataaaaaac
    22081 gaatagagtt ctaaaactcc tattcgtttt ttattcgatt acaatcatag acttaatggt
    22141 cttacgttca tccatatctt tgtaggcttg gtcgatatct tccagtttat aacttgaagt
    22201 aaagacgcga cctggattga tatcaccatc aaggacggct tttagtaaaa attgcttatc
    22261 gtatgttgta gcagaagctg ccccacctgc tacagagata ttttgcataa atgtcgaacc
    22321 aagagcacga ttattatagt gtgggactcc tacaaagccc atacgccctc cattatgaag
    22381 aacacctagc gcctgttcta tagcagcctc cgtaccaaca cattcaagtg ctgcgtctgc
    22441 tcctccaccg aggatttcac gcaccttggt aattccttct tgaccacgtt ctgcaacaac
    22501 agctgtcgca cctgactcca tagccatctt ttgacggtct tcatgacggc tcataaggat
    22561 aatttgtgat gctccacgca tcttagccgc gatgacagca cattgaccaa cagccccatc
    22621 accgataaca acaaccttgt cccctttttg aacatttgca acacgcgccg catgatagcc
    22681 tgtcggcatg acatctgcaa gagtcaaaag ggactggagc atcccttctg tatagtcaga
    22741 aggttgacca gggattttaa ccagcgccca gtttgcatag tggaagcgaa tatattctgc
    22801 ctgaaaatca ccccccaaat tattgccaat atgattgtcg caagaaccgt caaatccagc
    22861 aagacaggca tcacactcac cacatccatg tgtaaaaggg acaatcacaa aatcacctgg
    22921 tttcaccgtc gtaatggctt ccacagcttc ttcaacaatc ccaatcgctt cgtgtccact
    22981 atttttgtgt ccagctttcg tttctggatt acggtacctc cataaatctg aaccacaaac
    23041 gcacgcacga accacacgaa taatcacatc atccgcttct attatttgcg gacgttcaat
    23101 gctagcaagt ccaacctgac ctgcctttgt atatactgct gatttcattt aaaattttcc
    23161 ttccttataa agtttaattt tgagatttaa acgatttaaa gctgtctgta gctgagacaa
    23221 gcgctcctct aatttttgct tttcctcttc taaaatacca agcctctcct ctctcgtttc
    23281 atctcccttt tggtagagcg acatatagtc aactaaacta tctacagaga cacccgccga
    23341 acgaaaacac ttaataaatt ccagcgcttc gatatcctga tcttgaaaat cacgaatccc
    23401 agtagcagta cgagtaatcg gtggcacaag accaacccgt tcataatacc gaatcgtatc
    23461 cgctgaaatt cccaacaaat cactggcaga tttaatattc acacgctaac ctcctctcat
    23521 ttcattcact gaattcacgc tattctaact cacttatctt attatataac tttgagttga
    23581 ctccaagtca agcattttgt atctaatcga aaaattttta tcattaacaa tcatatatct
    23641 ggagtttata caatgctctt ctcttaccaa tttttgaaat atttaaataa taaagaaatt
    23701 actctattcc aaataagata gtacccaagt atttttcact tttttctaat gttgatgctc
    23761 ataactccgt tccaagtcac acacctttcg cttatgggtt tggtgagttt ctaggtcagc
    23821 atcaatttca atggtaatat tttgaaaacc acaatctttt aggaaaattc gaatagactc
    23881 tttacaagtt tccatatgtt ccatttcttt tagacaaaca tggacaatgg catttttttc
    23941 caaagcatcc atagtccaga gattaagctg attaaggctg gccacattgt ccaatcgctc
    24001 caggccactc tttacttgct tgatatcaag accttctggc acagcatcca agaaaatctt
    24061 gagtgtagac caaaaacgtg gaagggcttt tgaaagaata aagaaagaaa tgacaaggga
    24121 caaaagagga tctaggatat accagtccgt aaatcgaaga acaatcgcca tcaggataac
    24181 agctacccac cctagcgtat cttccagaaa atgcagactc agaatagact cattctttgt
    24241 ctttccctta ccaaccacca gactcgctaa cagattgata gtaatcgcaa taattcctaa
    24301 ccagagaatc ccctcatcat tgactggttg cggatgcaaa atcttcgtga cattttccaa
    24361 aatgactaga acagagcccg ttacgagaat cacagctgtt accaaggctc ctagcaggct
    24421 aaaccgctta tagcccaagg tgtactgatt gtcttcttca cgattggaga ttgtttctag
    24481 aaaagctgat attccaattg caatcgcatc tcccaagtca tgcacagagt cagcaagaac
    24541 agcgctagaa ccaaatactc cacctgcaat aaactcaaca atggcataag tcaaatttaa
    24601 gaaaaaagcc acccaaacag catattttgc cttcatattt ctcattcctt tgttataata
    24661 gatttatgaa caccttgttc attatcatta tccactaaaa ctcaaagaaa ggatagaagc
    24721 aaaacgtcag ctttattcag ttctgaacaa tttgccttaa gtgtccatat gactaacatt
    24781 gaccgccgta tcagcaaaac caaaaaagcc atctatcaag cttttataca acttttgaat
    24841 gctaagggct acgaggccac tactgttcag gatatcattg atctcgcaga tgtgggacga
    24901 tccacctttt actgtcacta tgagagtaag gagcttcttc tggaccagct ctgccgctac
    24961 ctcttccatc atctttttga aagagagcaa gccatttcaa ccgaggacta cctcgcccac
    25021 ctctttctcc attttcataa aaaccaagac catatcacca gtctgctatt ttccaaaaat
    25081 gactacttcc tccgtcaact ccataaagag ctagaacacc atgtctattc cgtgctagct
    25141 gataatttaa aagaagccca ccctaatctg cctacttctt acctccaaca cttggtcatg
    25201 tccaacttta tcgagacatt gacctggtgg ctcaaaaaag gtcaagattt cacagaccag
    25261 gaagttgtcc aattttatct agaccttctc attcctaaaa attgaatata gagtaaagct
    25321 tcagttgtct tatttctagg ttactgagtt ttttatcttt tcaacaacaa aagaggaccc
    25381 gccgatcctc tttttcatac tataaatcct tgattatcaa ctatatctgt tttaatcgaa
    25441 atctcaaaac agcactttca aacatctttt cctagttaag taaatcagta ttctgcttag
    25501 ctgccttgct ccattgatac caaccaacta gactgttaat gagataaatt agatatttcc
    25561 cttgaatttg caggctttct ccccaccaga gatagattga aaagacattg gtagccgccc
    25621 agaatatcca ctgttcacgg taaacagctg tcatgaggat ttgccctacc ccattggttg
    25681 catctgtgat tgaatcacga tagggacgat tggcaccaat agactgataa atgaagccaa
    25741 aggccaacca ccaaagcaca ctaatggaaa gatactttgt ccagcccttg ccgtccagtt
    25801 tacgcgcgac aaactcctgc ttttccttct taaactgtgc ctgataaatc caaactagaa
    25861 gtccaattgg ctgcatgact gtgaagtaaa gtgtcgtcag cacctcacca taaaagcctt
    25921 tctgtagggc caaaataagg taaataacag agttaatcaa gccaaaaaga taattacttg
    25981 ctcgaccttc cgatacaaag attacacaga taatccctgt caagctacaa atcatcccaa
    26041 tccagtcaac aatacgatgt tcgtaaacca actccagcca gagaggaaaa cttcctaaaa
    26101 ccagcaaata aatccactgg gcaaaactac gatgggcaaa gaggtcatcc cagatagcct
    26161 tcatagttcc tgaaaatcct aaatcagcca tagccgcaac catacgacgg taaccacctg
    26221 acatttcacc tagggttgtt ttgatatttt caattttctt ttgcaaataa gtatgcatca
    26281 tttctccttt tgtttttaaa gagccgtgtc tggatagact ttcggacgca acgctctatt
    26341 agataatgaa ctgcctatac acaagatttc taaccttagt cgacatgagc tgaaacctct
    26401 tatttgttaa gtagttcaca aaatattata cacctatttt atgaatagtc aactgtcttt
    26461 acagtaaaat tttagaaaat catgaaaatt ttctctttct ttccatttta agtgacattc
    26521 agtcattctc acatcaaaaa agcccagacg aaattgtctg agcattcttt tatctagtcg
    26581 tttaaggaag ttgagttcag tatgtttaaa gtctctgtcc catcatttct tcaacaaacc
    26641 ttgttcttgg agaaactcct tggctacttg ctttgctgac ttgccttcaa caccgacttg
    26701 gtagttgagc tggctcatct ggctttctgt aatcttacca gccaatgtat taagaactct
    26761 ttccaactct gggtgtttct tgagaagagc ttctttcatg agtggagccc cttgataagg
    26821 tgggaagagt tgcttgtcat cttccaagac ctgtaaatca taacgctcca attccgcatc
    26881 agtcgaatag gcatccgtga tttgaatatc ccctgactga atagcctgat agcgaagggc
    26941 tggctccatg gtcgctacat tgagattgag accatacatt gattgcaagc ccttatttcc
    27001 atcttcacgg tcgttaaact cgagtgtaaa acctgccttc aactgccctt ccactttttt
    27061 caagtctgaa atggtcttca agccatattc ttgagcaatc tttttcggaa cagctacagc
    27121 ataggtgttt tgataagaca tgggtttgag ataggctaga tgatcctgct tagcaatgcc
    27181 atcacgcgcc acctgataaa cctgttctgg ttcatgactc accttgggtg atggttgaag
    27241 caaactttca gtcaccgtac cagtaaattc aggatagatg tcaatatcgc cttttttcag
    27301 agcttcataa aggaagcttg tcttcccaaa attcggttta acagtcgcag tcatgctggt
    27361 attttcttca atcagcaact tatacatatt ggccaaaatt tctggttctg gacctatttt
    27421 cccagcaata accaagtttt ccttctcttt ttgaaccaaa agagctggac tataagacag
    27481 acccagtaat aaagccacca aggcaaaacc tgagaaaatc gtccgtaatt ttgctttttc
    27541 catcactttt agtaggaagt taaaggcaat ggctagcact gcagaagaaa gtgccccaat
    27601 caaaatcaaa ctggcattat tacggtcaat tcccaaaaga ataaaggaac ctagtccccc
    27661 tgcaccaatc aaggccgcca aggttgccgt accgataatc aaaacagctg ccgtccgaat
    27721 cccagacatg ataacaggca tggcgagtgg aatttcaaat ttcttgagac gttcccatct
    27781 ggtcatccca aaggcaatcc cagcctcttg caggttcgga tcaattccct tcagcccagt
    27841 gatagtattt tgcaaaatag ggaaaatcgc ataaatcact agagctgtca aagccggcaa
    27901 ggtcccaatt cccatcaaag ggataaagag ccccaacaag gccagagacg ggatggtctg
    27961 gaaaatacct gcaatctgca agacccagtc ggccagcttc tcatgatagc gaagaaaaac
    28021 agccaaggga atcgcaagca aaatagctag taacaaggtc aaaagcgaca actgcaaatg
    28081 ttgagataga gctgtcaacc aatcactaaa acgatcctga aaagttgcaa ttaaattagt
    28141 catgaacact acctccaaac aagtctgcta caaagtctgt tgcaggcgct tttaaaattg
    28201 tctcgggatt cgctacctgg cgaatttctc catcctgcaa gacagcaata cggtccgcca
    28261 acttcaaggc ttcatccgta tcatgggtta caaaaatcgt tgtcatccca aactctttat
    28321 gcaattcttt tgtcagaacc tgcaactgtt ttctcgaaat agcatccaag gccgaaaagg
    28381 gttcatccat gaggaaaatc ttgggctgac caatcatagc tcggacaata ccgacccgtt
    28441 gctgttctcc accagataat tcactaggta agcgatgccc atactcggct actggtaaac
    28501 caaccttagc caaaagctct tctgttttct tcgtaatttc ttccttgctc caccccttca
    28561 tttcaggaat gagagcaata ttttccgcaa ctgttagatt tggaaaaaga gcaatagcct
    28621 gtaaaacata accagtagaa agacgaagtt cacgctcatc atagtctttg atgcgcttcc
    28681 catccatata aatatttcca tcagttggtt ccaaaagacg gttaatcatc ttgagcatgg
    28741 tcgtcttacc tgacccagaa ggccctacta aaaccataaa ttccccatcc tcaatctgta
    28801 agttgacatc tctcaagaca tccttttctg tgtagcgcag tgctacattt ttgtattcaa
    28861 tcattctttg tcctcaattt aaaacttccc tcgattggtc aagtcttcta ccttaggcat
    28921 aacttcctta ttatcccaat gctccacaat tttcccgttc tctaaacgga agatatcgta
    28981 ctgggcataa gcaacgccat caatctgagt ctgaccatag ctaaccacat agtttccttg
    29041 tcctaagagt tggaaaacaa agtcaaaagt gacactatat tcagccacat agtttttata
    29101 agcagcactt ccttgtccaa tatcatgatt atgctgaatc aaatcgtctg ccacataatc
    29161 actccactgc tctagctccc cattttggaa aatttctgtc aagaaacggc gaaccagctt
    29221 tttattttct gctttcttgt ccaaatcctt gatttcaaaa tctccaaaaa tttgatctag
    29281 ttggtcattt tcaggtgttc gatagtagtc aacgacatcc caatgctcaa caatacgacc
    29341 attctcatcc gcacggaaag tatccgtcgt cacccattga gcttctccac cattcagata
    29401 ttgatgaaca tgaacaaaga ccagattgcc atcctcaatg gtgcggacaa tcttaatctg
    29461 acgctctgga tgacgctcaa agaaatctgc aaagaaggct gcaaatcctt ctttcccgtc
    29521 aggaacacct gtcgaatgtt ggatataggt atcccctaca gactgggctt gagcctcagc
    29581 aactcgcccg tcttgaatgg catggatgta taggttgtga gcatttttca cttgttgtga
    29641 catattctaa acctcatttc ccttctcttt cagattcgcc aaaattcttt cttgaaaacc
    29701 ttcaaattgg tgaatttctt cctctgaaaa tcctttgtaa aagatagtat ccaatttctg
    29761 actgacacga tgccccactt ctttctggaa cttgcctaac tccgttaaaa ctaaatactt
    29821 cttacgcttg tcttttccac acggactaac aattacaagc ttttgttcct ctagcttttt
    29881 tatcatagtc gtcagcgtat tattcgcaag cccagtcgca agcgcgatat ctgtcgcagt
    29941 tgcgcagcca gtttcactat tccataaaac cgctaaaatc ttgccctgtt cacccctata
    30001 aagagcctca ggatcttgac tcagtaactt ttgaaaaatc cgcccattca acaaacgaat
    30061 atgatgggct agcaaatgac tatctttcat aacacctcca atttatttcg atatcgaaat
    30121 gaataaaata attgtaacac tcatcgttct aactgtcaac tatttcgatt tggaaataat
    30181 ttttgataat tatccacacc accatactcc ggctcaacta acttttaacg agagtttcta
    30241 aactccttcg tcctccagtc tacaaaagcc ttccattcgt actatcctat attttatgag
    30301 gggacacatt tttcctatca gaccatttat tttaaagata gaagtaaatc ataattgctt
    30361 ccatctgttc ttttatagta tattgaagtt agactagagc actgtatctt ctaaaacatt
    30421 gatagaaagc gatttgaatt tcccaatcaa tttgttcgta tttatagcat tttgaaacta
    30481 gaataggaca ccatgactgc taaaagattt ctataaattc atttgatttt cctaatcaat
    30541 ttgttcatat cttatttcat tccgctataa tttcacctta ccctatcttt ttcgtagcac
    30601 ccttcaaaca gcctatcccc taccgtttga cgattcctca cttcgctcca cttccattac
    30661 agaagtttct tcactactat gggctcggct gacttctcat gattccttgt tactactatt
    30721 tgaacgctca cgagatagat cttacaaaaa atgctttgat ccacaatgga atcaaagcat
    30781 tttaaagagt tcctcataca taagcgcaga agtcgcagtt cctctgtact tggcttcttc
    30841 tcttttgata aagcgagcca agttgagcaa ctcaggtgct ggatgtttgg gatttaggag
    30901 caattcacga ttgaccaggc ctgagagacg aactgcctgc aattgctcat ttgtagtagg
    30961 cagtttttta gcagtctcta ggagagcagc aactaaatct tcactcaaat catgtcgagc
    31021 atgattgtaa agatctttta taaggctttc taggtttggt tctgccatcc ctaccacctc
    31081 ccttatggtt taataatgtt taatcaaatc aaccgttgaa cgatccaatt tcttcaccaa
    31141 ggcttgtaag aaagcttgcg cttctaggaa gtcatccatt gcatagaggg tttggtgaga
    31201 atggatataa cgagcgcaga caccgatagt tgttgatggg acaccaccat ttttcagatg
    31261 agctgcacct gcatctgttc cgcctttacc acagtagtat tggtacttga taccagcttc
    31321 ttcagccgtt gtcaaaagaa aatccttcat ccctgggaga agcaagtgac ctggatcata
    31381 gaaacgaatc aaggttccat ctccaatctt gccttgacca ccgtagacat cacctgctgg
    31441 tgagcaatca actgcgagga agacttctgg gtcaaacttg gttgtagagg tatgagcgcc
    31501 acgcagacca acttcttctt ggacgttaga acccagatag agttcattgc cgagtttttg
    31561 acctgataaa gcttcagcta gctcgcttac catgaggaca ccgtagcggt tatcccaagc
    31621 ttttgagatg atattttttt cattggctgt caaaattgca gaactatctg gtacgatggt
    31681 atcaccagga cggatgccaa aactttctgc ctcagccttg tccgcaaaac caccatcaaa
    31741 aacgatatcg gcaatggctg gcatggttgg tccccccttt ccacgagtca aatgcggagg
    31801 aacagaacct gaaatcacag gaatttcatg accatcacga gtcaagagtt tgaaacgttg
    31861 gctgctaacc accatggggt tccagccacc gatttctacg acacggaagg taccatctgg
    31921 cttgatttcg ctgaccataa aaccaacttc gtccatatga gaagcgacca agacgcgcgg
    31981 tgcatccaca gcttctgaat gtttgatacc aaaaatacca cccaagccat ctgtcaccac
    32041 ttcatccaca tgcggtgtca acttttcacg aagataagca cggacaggcg cttcatgacc
    32101 tgagactgca gcaagttctg ttacttcttt aatttttgaa aataatgttg tcatttcagt
    32161 tccttctttc tttcatccat tttaccactt tttataggag aaggatagtg ggaaggtgga
    32221 tttctaagtt agtatcttag tcctgctcta tcttagaaaa ggatagtatt ctcttgcatg
    32281 tagtgcaaaa tctagtaaac attccaaaat taactcgaat atttatttcc aaacaaaaaa
    32341 acaatacacc atcaaagttg tttgtatttt tcatgaaatt tacagaaaat agttgacttc
    32401 cctttcttct ttctttaaat atatagttgg ttgagtttgg aatagtacgc tgtagctgct
    32461 gaaacatttc tagaaattaa tttgactttc ctaatagagt tgttcatatc ttatttcaat
    32521 ttactatagt acaaaactag aaaaggaaaa aatcatgacc aaaacaattc ttgttacagg
    32581 tgggactagc tacattggct cccataccgt taaagctctt ttaaatgctg gctataaggt
    32641 gcatgtcctc gataatctct ccacaggaaa tcgagcggct gtggatagtc gtgctagctt
    32701 taaagaactg gatgtttatg atgctagcgc cttaaaggct tacttagaag aaaatcagat
    32761 tgatgctgtc ctccattgtg caggtgaaat tgttgtgagc gaaagtattg aaaatccaag
    32821 taaatacttc actgccaacg ttgctggtat gaaccaagtt ctcaaagtct tatctgaagt
    32881 tggcattcaa aaaatcatgt tctcttcgac tgcttctctc tatggaaata actgtattga
    32941 caagccagtg actgaagata ccctgctcga ccctgtcaac ccttatgcag agacaaaact
    33001 gatgggcgaa cgaatgattt actggatggc caatcgctac gactggaaat atgttatttt
    33061 ccgttacttt aatgttgctg gggctgaaat ggatgcttca aacggtctgc gtgtgaaaaa
    33121 tccaactcac atcattccaa atatcaacaa gaccgcattg ggacaaaatg atagcttaaa
    33181 aatatttgga gatgactacg atacacgtga cggttcatgt attcgagatt acatttatgt
    33241 cttggacctt gcataggctc atgttaaagg aatgaactac ctatttcaag aagacagttc
    33301 ttctcaaatc tttaacttag gaactaaaaa aggctatact atcaaagaaa tctttaaaac
    33361 tgctgaagaa ttactaaatt aaaaaatccc acacgagatt gttgctcgac gtgctagtga
    33421 cccagccagt gtcctagcag atgcttcaaa agctaaacaa tatcttgatt ggacggctag
    33481 ctactccctc gaagatatta ttttatcaga ttaaggtaaa aacattttag aataggataa
    33541 caaaggagaa agtcttgttg ctctctcctt gttgtattta ttaaattgtc agaaatttta
    33601 ttgacagatt agaaaaataa tgttacattt atatccgcag atatctttcg ataccaaatc
    33661 tacatgaaag gacggggtat gaaactttct cattatttaa ttggcttact tctactccta
    33721 gtctttctct ctattagcat tgggaccagt gatttttcat ggggaaagct atttgatttc
    33781 gaccagcaga catggctcct ctttcaagag tcccgtctcc caagaactat cagtattctc
    33841 ctgactgcct ctagtatgag tatggcaggc cttctcatgc agactattac ccaaaatcag
    33901 tttgctgcac cgagtacagt tggaacgact gaagccgcca aactgggaat ggtgctgagc
    33961 ctttttgtct ttccatcggc tagtctgacc caaaagatgc tcttcgcttt tgtttcatcc
    34021 atcgtattca ccctcttctt cctagccttt atgaccattt ttactgtaaa ggaaaggtgg
    34081 atgttgcctc tgattgggat catctatagc gggattatcg gctcagtcac agaagttatc
    34141 gcctatcgtt tcaatctggt tcagagtatg actgcctgga cccagggctc cttctccatg
    34201 attcagaccc atcagtatga gtggctcttc ttaggcctca tcatcctgat aaccgtttgg
    34261 aaattatccc aaaccttcac catcatgaat ctggggaaag aaatcagcga gagtttgggg
    34321 atttcctact ccctacttga aaaactggcc ctctttctgg tggcgctaac gacaagcgtc
    34381 accatgatta ccgtgggtgg cctaccattt ctcggagtta tcgttcccaa tcttgttcgc
    34441 aagcgctatg gagataatct aagtcaaacc aaactcatgg tcgcactggt tggtgccaat
    34501 ctagttctgg cttgcgatat cctatcccga gttctgatta ggccctatga gttgtctgtc
    34561 agtctcttgc taggaatcat cggtagtctc ggctttatcc tacttctctg gagaggggga
    34621 cgaaaagatg cagactaaaa gcaaacatac caagctcttc tggattctca ttattcttgc
    34681 catcggagct tgtcttctct acttttggcc catcactcac ttgtcagcct ttgcttggaa
    34741 gttgcgttcc caaaagatca tcgtttatct cttggtagcc atcgcgactg ggatttcgac
    34801 cattagtttt caaaccctga cggaaaatcg cttcctgacg cctagtattt tgggaattga
    34861 atccttctac gtcctactac aaaccctact actggttttt gaaagcaagt ttcttcaact
    34921 tggcaaatcc cctatcttag aattcctagt cttacttctt gtccagtccc tcttctttct
    34981 caccttacaa ggttacttga agacactgat gaagcaagac ctggtcttca tcctgctgat
    35041 ctgtctagcg ctcagaagtc tctttcgaaa tatcagcacc ttccttcaag tcctaatgga
    35101 tccaaacgaa tacgataaac tgcaaaatag tctttttgcc tcctttcaac atctcaacac
    35161 ttccatccta gccatcggtt ctctgatcat cctcgctttg acaatctttt tctttcgaaa
    35221 agcagtcgtt ctagatgtct tgcacctgca aagagaaacg gctcagatat tgggactcga
    35281 tgttgaaaaa gaacagaaag agctcctctg gggaatcgtg cttttgacct caacggccac
    35341 tgccttggta ggacctatgg ccttcttcgg ctttatgctg gccaacctca cctacctgat
    35401 tgtcaaagac tatcagcaca agttactctt tatagtggcc attctggttg gatttattag
    35461 cttaaccttg gggcaagcct tgattgaacg agtctttgca ctggaaattc gtatcagtat
    35521 gatcattgag agtgtgggtg gcttcttatt ctttatctta ctatatagga ggtctcgtca
    35581 gtgaaactgg aaaacattga caaatccatt caaaaacagg atattttgca aggcatttcg
    35641 cttgaagtca gtcctcaaaa actgacagcc tttattggtc caaatggtgc tggaaaatcg
    35701 actctcctct ccatcatgag cagactaacc aagaaagatc agggagttct cagtatcaaa
    35761 ggacgtgaaa tcgagagctg gaattcgcaa gaactggccc aagaactaac catcctaaaa
    35821 cagaaaatca attaccaagc caaattgact gttgaagaac tggtcagttt tggacgtttt
    35881 ccctacagcc gaggtcgact tagatcagaa gactgggaaa aaatccgaga aactctgaac
    35941 tatttggaac tgaccaactt aaaagaccgc tacatcaata gcctgtcagg ggggcaactc
    36001 cagcgcgtct ttatcgctat ggtactggcc caggatacgg actttatctt gctggacgaa
    36061 ccactcaaca atctcgatat caagcaaagc gtcagcatga tgcagattct tcgacgactg
    36121 gtggaggaac tcggcaagac cattatcatc gtcctccacg atatcaacat ggccagtcag
    36181 tatgcagatg aaattgtcgc cttcaaggac ggccaggtct ttagcaaggg aagcaccgat
    36241 caaatcatgc aggctgacct gctcagtcaa ctttatgaga ttcccatcac gctagctgat
    36301 atcaatgaca aaaagatctg tatctatagc tagtaacata aaagctcaag ttagagaacc
    36361 ttcagtctct tagtcaataa gattaagaga ctccctaaat cgttatcaca ttttaaaaag
    36421 gagaaattat gaaaacatcc cttaaacttt atttcactgc cctagtggcc agcttcttgc
    36481 tcctacttgg tgcatgtagt acaaactcaa gcactagtca gacagagacc agtagctctg
    36541 ctccaacaga ggtaaccatt aaaagttcac tggacgaggt caaactttcc aaagttcctg
    36601 aaaagattgt gacctttgac ctcggcgctg cggatactat tcgcgcttta ggatttgaaa
    36661 aaaatatcgt cggaatgcct acaaaaactg ttccgactta tctaaaagac ctagtgggaa
    36721 ctgtcaaaaa tgttggttct atgaaagaac ctgatttaga agctatcgcc gcccttgagc
    36781 ctgatttgat tatcgcttca ccacgtacac aaaaattcgt agacaaattc aaagaaatcg
    36841 ccccaaccgt tctcttccaa gcaagcaagg acgactactg gacttctacc aaggctaata
    36901 tcgaatcctt agcaagtgcc ttcggcgaaa ctggtacaca gaaagccaag gaagaattgg
    36961 ccaagctaga caagagcatc caagaagtcg ctactaaaaa tgaaagctct gacaaaaaag
    37021 cccttgcgat cctccttaat gaaggaaaaa tggcagcctt tggtgccaaa tctcgtttct
    37081 ctttcttgta ccaaaccttg aaattcaaac caactgatac aaaatttgaa gactcacgcc
    37141 acggacaaga agtcagcttt gaaagtgtca aagaaatcaa ccctgccatc ctctttgtca
    37201 tcaaccgtac ccttgccatc ggtggggaca actctagcaa cgacggtgtc ctagaaaatg
    37261 cccttatcgc tgaaacacct gctgctaaaa atggtaagat tatccaacta acaccagacc
    37321 tctggtatct aagcggaggc ggacttgaat caacaaaact catgattgaa gacatacaaa
    37381 aagctttgaa ataagccact tcaaactcaa tttaatactc aatgaaaatc aaagagcaaa
    37441 ctaggaaact agccgcaggt tgctcaaaac actgttttga ggttgcagat gaaagctgac
    37501 gcggtttgaa gggattttcg aagagtataa aattttgaca ttctaaaacg catcctatca
    37561 agttcactca aacctgatag gatgcgtttt tatcattttg aaatctattt accccacctc
    37621 attccccttc ttgatttcgt ttaagggaaa agtggtctgg aacggggtcc ttacctgttt
    37681 tcgaccaggg atgacaacgt aaaatccgag ccaagcccat caataccccc ttaaaaccat
    37741 gtttttcaat agcctgaatc atgtagttgg aacaagtcag ctcaaagcga caagagggtg
    37801 gaaagactgg tgagataaaa cgttggtaaa agcgcacagg cgctattaaa attcgtttca
    37861 ttatttctta gttacagcca tggtgtgtag ttggctgatt tcttttttat taagacgacg
    37921 ggattctcct ggacggagtc ctgtcaagtc taggtgtccg aaacgagtcc gagacaactt
    37981 atctacttgg agaccaacag cttcaaacat ctttttaacc tgatggttac gcccttcatg
    38041 gatggtcaac tgcaccacag agcgattttt gactgggtcc actttgagaa tttcataaac
    38101 agctggcttg gttttcttac catcaatctc aagaccacgg gtcaaggggc ggagattgtc
    38161 cttattggcc acacccttaa cacgcgcgac ataaaccttg tcaatctcat tacgagggtg
    38221 aatcatctcg tctgtaaagt ccccatcatt ggtcaaaatc aagacacctg atgtatccca
    38281 gtccaaacga cccacagggt aaatacgctc tttgacattg ggcaagaggt cgacaaccgt
    38341 cttgcgaccc ttatcatctg tcacactgga aatcacaccg cgtggtttgt taagcagata
    38401 gtagaccttt tcttcgttgt agataggttg accttcaact tcgaccttgt cgcctgactt
    38461 gatagtggtt gctagttcac gcaccacttg gccgttaacc gtcaccaagc cttgcttaat
    38521 cagctcttct gcttttctcc tactggccac acctgcgtgg gcaatatact tattgattct
    38581 catcttcttc tatcctttca ccaaataatt ggctttcttg ggcttgaatc tcaagctcat
    38641 caatcactgg taattcttct aaatggttta tccccatgta atctaggaaa taatccgtag
    38701 tcacatagag gttggggcgc cccaatactt cctttttccc gtcttccttt atcaggtcaa
    38761 aagcctgcaa ctttgccaag gctccactcg agttaactcc acggatggca tcaatttcta
    38821 tccgcgtaat cggctgtttg taggcaataa tggacaaggt ctcaagggca gcccgagaca
    38881 agctctggtt gataggcgcc ttagagtatt ccttcaaaat ctctgcaaat tgagacttgg
    38941 tcaccaatct ataagcacca cttgtctcaa tcaaagccaa actggaatct gggtcctttt
    39001 catacttctg ggctaatttt cctaaactct gctggatgcc tgtcggtggc agagagagga
    39061 gttcagctaa ctggcggacc cgaatcccat cttcacccgc tacaaacaag agcgcttcta
    39121 tttttgctaa agtactcatc tttcctctct atcaagtcta gctttgaggc acttgacttt
    39181 cttccttctt ttccatgaga tagatatctc caaaactctc ctcttgcacg aggatcagct
    39241 cctgggtttt gattaactct agggttgcca aaaagagggt gatgacctct tggacattct
    39301 gggcttcctt gaacaaatcc tgcaagcgca attgatctcg tccaatcaag gactctttca
    39361 cgataatcat catgtcctca atcttatact catcccgcaa gatagtcgtg tgattttgtg
    39421 caaactcctc ttttttcttg gctaggatat ttgaaaaagc caaaaagagg tcaatggtcg
    39481 tcttgtcatg cacaagctcc gcatcttcgt aaatcaactc tgtcggcgct ttggaataat
    39541 actgggcccg ttcttggtgc ttggcttcca agtgctcacc caagagcttg aacttgcgat
    39601 attcttcgat ttgagagagg aggtcctgct ccaggtcatc ccccaagtct gtcacttctg
    39661 ctaccttcgg aaggagttta cgactcttaa tcagcatgag ctgactagcc atgaccatgt
    39721 actcacccgt cacttccaga cgcatggcct gcagggttga aacataggct agatactgtt
    39781 cgatgacttc cgtaatgggc acatcgtaga tatccatctg gtacttagaa accagatgca
    39841 agagcaagtc cagggggcct tcaaaatctt ttaatttaat atccattatc tatatttttc
    39901 taaggtcagg actgttttta atcctaattt ttttgcaatt tcgtacaaat cgaccttgtt
    39961 ttctatttgt cttagaataa actgttcacg taagacttga gctgataagg atggaaaacc
    40021 tttctccttg acaaaagatt ctaactgacg aaaggcccac tgacgagaat agggtttctc
    40081 tcctctttca aaaagatagg tctgccccat caagggttcc aattctgaaa gcaaggccgt
    40141 gggaatggtg acaatcctct gttgggaagc cttgctgatt cgcaacacct gaaaatccag
    40201 attgatgtcc gcaaccttga tggctaaaat ctcactgggc aagagcccca tttctaggat
    40261 taagagcgct agcaagcggc cctctggatg gtcgctttcc tgccaaaaag agtctaggta
    40321 tagaatctct ggcttttccg tcttcttttc agcttgtttg gctaattcca agcggtaaaa
    40381 gctgtccacc tctccttttt gatagagaaa gtatagaaat tggttacagg ccgaaatctt
    40441 tcgcttctgg gcgctgattt ttagattggc tagctgggct tggtaaatct tgagactggt
    40501 ctcagaaatc cgctcaccta ccatgtctaa aaattgctcc aaatcatact tataggactg
    40561 cttggaattg acagacaagc cctgcttttc ctctaaaaag gctgaaatcc tgtctctcat
    40621 tggcatcgaa tctcatattc cttactaaag tcatgcaaga gggcattaac ggccttgagg
    40681 atggacttac gcgtaataat cccttggaaa ataccctctg catccacaac cggtaagaag
    40741 gactcatcta ctagcttgtg caagacctcc gtaatggtga aatcaggcga aacaaccgct
    40801 acgtccgttt ttgtcatatg aacgatatcc gtatccgcca tgatttcttg gctcaagtca
    40861 tgctccatct gataagccat aatatctctg agtccaatcg tcccaacaaa ctgtttttca
    40921 tctgtcacaa cgggaacacg ggtataggtc atctgactga gcaagagggt cgcatgatcc
    40981 gcattgtggg tatcaatcaa cacagctaga tttttagcag gggtcaaaaa agtttcctcc
    41041 tgccccaaca agaaagtctc aaactccttg gcaatcatcg gctaaactcc ttggacaaac
    41101 ctggatacac ctcgtgatct cgtgtcaaaa agtccacttt gaagtaacta tcatcaatct
    41161 ccacacgagc atagagacat tctctgatgg tacctcgtgg ttgactgata gaacctggat
    41221 ttagaaagag gatcttgcct tccaaccaag cacttggcac atgcaagtga ccatagaggc
    41281 agatagcggc ctcttcctcc tgagcccagt agtccaactt ttgaaagttg aaattgatgt
    41341 caaacaagtg accatgagtt tggataatct tggtcgaacc aagctcagtc accagacgtt
    41401 ctgggtagcc ggcgtagaag tccatgtttc ctttaacaac gcggatgccc tcccaaagtg
    41461 gagaatccgg acgtagttca gaatcgccgt tatgaaaaac ggcatcgact ttgcccacat
    41521 agcgatcacg gacttcttcc acaatcaagc tatcgccatg ggaatcgctc attacaatga
    41581 tggtttgctt tgccatgatg gaaatacctc caaaagtttc ttaacggcta aggcacggtg
    41641 agattgacta tttttttctt ccagggttaa ttcagctgat gacttacctg tctctcctac
    41701 aaggaagagg ggatcatagc caaagccatt ttcaccctta ggttcaaagt taatataacc
    41761 tgaccagtct gcttcaacaa ctaaactttc cttatttggg ctggctacga ctagggttgt
    41821 gtggaactga gccgagcggt ccttgagttc aaagaccatg gccaattcgt gcaagagttt
    41881 ggcattattt tcacggtcag ttgctcccac acctgcgaaa cgagctgacc agacgcctgg
    41941 taagccacca aggacatcga ctttgagacc agaatcatct gccaaaacca tcttgcccgt
    42001 taattgagaa atggtttctg ccttaaggcg ggcattttct tcaaaggtca tacctgtttc
    42061 tgctacttca ggcaggtcag ggtagtcatt aagattttcc acatcgtagc ctaacttatc
    42121 aaagatagct cggaattcct tggttttgcc ttcgttacga gtcgcaatca acaaggtttc
    42181 tctgaccttg cttgtctcaa agaaatcatg aacattgacc ccttctttag gcaattctac
    42241 atacaagagt tgcccatttt caaccaagag cagggcccca tgacgttgaa taacttccaa
    42301 gtttcgtccc atttcttgat taagcatgtc taccacaaag gagaacaaac ggtaggtaga
    42361 accatagcgt aaaacagtaa ctgaaagcgg gaaaccatac tcttcatctc caaatatttt
    42421 ggagaattca aacagaggaa aatctgtctt atagtcgctc aaactgttaa cgccaccaaa
    42481 aatactataa gacccaacat accaatcctg gtcatcctta tattcataaa ttttatttgt
    42541 cataattcta catgctccac ataaatctct ttttccagcc attcttcacc aatttgtgca
    42601 aaactttggc tactggctgt tgtgtaaaaa cggtgatgga gtggtccagc atcgcgacca
    42661 cgattgattt caaaataatt gagtaagact gagatatccc gtacgcactc tgccccacta
    42721 tcgatgagct gaacctttgg ccccatgaca ttttggataa tagggcgaag gagtggataa
    42781 tgagtacagc ccaaaatcag gctatccacc tttccaacca agggacgcag ggtttcatag
    42841 accaccttct tggtaacact ggttgacagg gcacctgact caaccaaggg agcaaacttg
    42901 ggacaggcca agctctccac ctgtaagtcg ggatccagat catggatttt ctgacggtat
    42961 atgtctgatt gtaccgtcat gggcgttcca atcactccga ttttcccacc ttgactggac
    43021 ttgatggctg ccgaagctcc tggcaaaatt acacccaaga caggaatatc tagttgagcc
    43081 ttgatttctt cccagacgac cgcagtcgca gtgttacaag caatgacaat cattttgaca
    43141 tccttggtca agagaaagtt gaccagctgc caagtatatt cacgaatttg ctcagctgga
    43201 cgggggccat agggcgcccg cgccgaatct ccaatataga cgatttcttc atggggaagc
    43261 tggcgcatga gctcgcgcac aacggtcaag cccccgacac ccgaatccaa aaaaccaatt
    43321 ggtcgattat ccatacagtc ttctttctag tcttttttct gattgatcgt tcattatgat
    43381 tccttgtact gaacgaactg accgacagct tgatagaatg tcaactacct ctctcttaat
    43441 cataatcaaa tatcaataga atgcaaggaa aaagtctcat ccctaaacca taaccaacat
    43501 agtgagaagt ctggaacttt catcccagac ttttccttat ttattttttc tttttattgt
    43561 tagcaagggc tgccttttgt tggcggatga tttggtggta aacttgttgt accttagctt
    43621 cgcttggttt ttgaccattt gcactcaaaa gagtacgaac tgcttcagca ttcaaacgtg
    43681 ggttgtcagc aaattctttt tcgatttgct tacgaaccaa gtacattcct ccaagagctc
    43741 ctcctagaaa agctagcaca atcaatacaa ttgctaaaag taaatccatc atttttctcc
    43801 tgtttctttt tgagtccctt tcattatacc acaaactagc caccctgacc agtttgttct
    43861 acactttcag ggatggaata gacagcaaaa agaaccctgc ttttctgaaa aagaggtctc
    43921 cttgctaagt ttaatttaca taaatagcca gtgtttgata gggttttagt agaattttct
    43981 cagacacttc tgcatcttca tagtttgaaa tcaaaatctg tccattttgg tagactgctg
    44041 gcaagtcgat ttccacttct ttagcataaa agttattgag cactagtaac ttttgatcct
    44101 caaactggcg ttcaaaagcg tagacttgtt tgctatcttc aaaggctggt ttgtaacttc
    44161 cttctgaaat gattggcatt tccttacgca gtcgaatcaa gtcttgatag aaggtaaaaa
    44221 tcggaccctg gatttcattt tctacattga tgtctttata ggatttacca gctttcaacc
    44281 aaggagtgcc tgttgaaaat cctgcatttt ccgaagcatc ccactgcatg ggaatgcgtg
    44341 aattatcacg cgacttagct tgaataatct ggaaggcttc ttgctgactc tttccttctt
    44401 ctaggagcat ctgataggca ttaagcgatt cgacatccac gtaatcagcc atagaatcat
    44461 agtctgggtc aatcatcccg atttcctcac ccatgtagat ataaggtgtc ccacgtgaca
    44521 ggtgaatgct ggctgctagc atggtggctc cttccttgcg gaagttttga atatcgacaa
    44581 aacggttcaa ggcacgtggt tgatcgtgat tgttccaaaa gagggcactc caaccgtctt
    44641 tatcactcat ttccttaccc caactatggt aaagactctt caactcttca aaatcaaagg
    44701 gagccaaggt ccacttttgt ccatccttat agtccacctt gaggtgatga aaattaaagg
    44761 tcatggataa ttcctgacga tcaggcgacg aatagaggac acagttttcc atggtggtag
    44821 aagacatttc cccaactgtc ataaagctat cgtcagatcc aaaagtggct tggttcatca
    44881 tacgcaaata gttatgaacg atgggtttgt ctgtataagc tggcttccct tcattttcag
    44941 gacagtccac tgaaacctcg tccttaccaa tcaaattgat cacatcaaat cgaaaacctt
    45001 tgacaccctt gtcgcgccag aaattaacaa ccttgaaaag ctccttacgg acattgggat
    45061 tgcgccagtt aaggtcagcc tgggtctcat caaataggtg aagatagtat ttcccagtat
    45121 ccccgaaagg cgcccatgca gaaccaccaa acttagactg ccaatctgtt ggttggtctt
    45181 ggatgaagaa aaagtcttga taatacttat caccagctag ggctttctga aaccattcat
    45241 gctctgtcga acaatgatta agtaccatgt ccagcataaa gtcaatcttg tgctctttac
    45301 cgatacacac catttcctca aaatcagcca tatcaccaaa aagaggatcc actgccatat
    45361 aatctgaaat atcgtaacca ttatcccgtt gaggacttgg atagaatgga ttgagccaga
    45421 ccatatccac acctagtttg gctagatagg gaatttttcc gataatccca cggaaatccc
    45481 caataccatt gccagtggtg tctttgtaag attttggata gatttgatag actacttttc
    45541 ctttatcaag tgtcatctgt ttctcctttt ctgataaaag ggaggaagca gtcttccgtc
    45601 cctatttgtg ctatttcaat tatactcaat gaaaatcaaa gagcaaacta ggaagctagc
    45661 cacaggttgc tcaaaacact gttttgaggt tgcagataga gctgacgtgg tttgaagaga
    45721 ttttcgaaga gtattagatt cgtgtagcga ccatgagaga tgctccagct tgaatcgttg
    45781 tcggataagt tccgggaata gtcgctgtat aagcatcttg gttggtgatg ataacaggag
    45841 tttctgtcac cagacctgca gccttaatga catccatatc aaaacgaatc agttgctgac
    45901 caactgtaac gtgatctcct tggactacaa gactttcaaa acctttgcca tcaagaccta
    45961 ctgtatccat accgatgtgg atgagcaatt caactccctc gtcagagaca atgccgatgg
    46021 catgcttggt agggaaaaga accgtcactg tcccattaac tggagaggtc aactcacctt
    46081 ggcttggttc aatgactaga ccttgcccca tgacacctga tgcaaaaata ggatccgtcg
    46141 cttgactcaa ttctttcact tggccagtta gtgggctgat aatttctacc gaagtaagtt
    46201 ctactggttc atggttcaca aattctgctt cttcttgagc aacgaattct gcctgcaagt
    46261 tcgtatcgcc ctctgttttt gtaaagagac cagccttgcg gaagaagaaa gtcaagagca
    46321 ttggaacaac aatcgcaact agcatagttc ctgcaaatgg cagcatgtat tgaggttgaa
    46381 tagagagaat acctggcaaa ccaccgatac caatagaagc cgcagttaca ttaaaagtaa
    46441 cggataacat gcctgcaagg gctgaaccag tcatcccagc aacaaatgga taaatatatt
    46501 ttacgttaac cccaaaaaga gctggttctg taacaccgag ataggctgaa atggttgcag
    46561 gaagtgaaac ctgagcctca cgctcatcat ggcgatgcat gaaataatag gcaaacacgg
    46621 ctgagccttg agcaatatta gaaagagcaa tcattggcca tagggcagtg ccaccagcat
    46681 ccgcaatcaa ttgtgtatca atggcattgg tcatatggtg cagacctgtg atgacaaatg
    46741 gagcgtagag ggcaccaaaa attgcaccga agagccattt aactggacca gttaaacctg
    46801 ccaagacaac tgatgaaagt ccttgtccaa ttgtccaacc gattggtccc aaaacagtat
    46861 gagccaaaat caaggctgga atcaatgaca agaaaggtac aaaaatcata gaaatgactt
    46921 ctgggatatg cttgcgccag aagatttcaa gataagatag actcaaacct gcaagcaagg
    46981 ctgggataac ttgggcttgg taaccgatac gattaacagt aaaatagcca aaattccaaa
    47041 cccagtttgc cgcgatatca gctgctggcg ttgaagcaac cgcataggca ttgagcaact
    47101 gaggcgatac caaacagatt ccgagaacaa ttcccaaaat ttggctggtt cccatcttac
    47161 gagaaacaga ccaagtaatc cctactggta agaactggaa gatagcttca ccaggcaacc
    47221 agaggaaatg attaacacct gcccaaaact gagaggattc tgtgatggtc ttgccatcca
    47281 acatcgacca atggacacct tccaagacat tacggaaacc gaggatcaat cctccgacta
    47341 tcaaggctgg aataatcgga gtaaaaatct ccgccagagt ggtcatgaca cgttggacca
    47401 cgttttgatt actcttagct gcagacttgg ctgcttcttt ggaaacaccc tcaatacctg
    47461 aaacagctgt aaaatcatta taaaagatgg gcacgtcatt tccaatgatt acctgaaatt
    47521 gacctgcatt tgtaaaggtt cctttaacag ctggaattga ctcgatagct ttaacattag
    47581 ccttcttatc atttcctaaa acaaagcgca tccgtgttgc acagtgagtt acggcagtca
    47641 cattttcttt gcctccgatt gcctgaagca gatctttggc ttcttgttca aattttccca
    47701 tttgattctc cttatacttg tcaaagcaag tttgatttga taagtatatt gtaaacgata
    47761 ccaaacttgt ctgcaacttg tttggtataa aaagggtgtt tttttgtaaa ttttctagca
    47821 cttgtatggt aaaatagata caggtgttca ttaaactaga ctaaaaacct atttaagcag
    47881 gcaaaatgaa gaaataccaa caattattta agcaaatcca agaaaccatt caaaacgaga
    47941 cttacgctgt cggagatttc cttcctagcg agcacgacct tatggagcaa tatcaagtga
    48001 gtcgtgatac cgtccgaaag gccctgtctc tcctccaaga ggaaggattg atcaaaaaga
    48061 taagagggca aggttctcaa gtcgtcaaag aagaaaccgt caatttccct gtatccaacc
    48121 taaccagcta ccaagaacta gttaaagaac ttggactgcg ctctaaaacc aacgtggtca
    48181 gtctggacaa gattattatt gataaaaaat cctcactgat aaccggtttc ccagagtttc
    48241 ggatggtttg gaaggtggtc cgccagcgtg tggtggatga tctggtatcc gttctggata
    48301 cggactatct ggatatggaa ctcatcccaa atctcactcg ccaaattgct gagcagtcta
    48361 tctattctta tatagaaaat ggcctcaaac tccttattga ttatgctcag aaggaaatca
    48421 ccattgacca ctcaagcgac cgagacaaga ttctcatgga cattggcaaa gacccttatg
    48481 tcgtttcgat taaatcaaaa gtctatctcc aagacgggcg ccaatttcag tttaccgaaa
    48541 gtcgccataa gttagaaaaa tttagatttg tagattttgc aaaacgcaag aaataaaaga
    48601 ctgagacacc agatctcagc ctttttcttt atcccaaaac taattcatca ctgaccagac
    48661 tttggccact atttttctgg aagagatgca taaggtcttc aactgtcaga tgctttttct
    48721 cttctccctt gacatccacc actatcttgc cttgatagag cataatgaga cgattgccgt
    48781 actcaatcgc atgattcata tcatgggtaa tcatcaaagt cgtccactga tggtactcca
    48841 caatcttttg cgtcaagtcc atcaccattt gactggtttt cgggtcaagt gccgcagtat
    48901 gttcatccaa aagcaaaagt ttgagtttca ccagagctgc catgactagg gtcaaagcct
    48961 gtctttgtcc tcctgagaga tattgagtat ctacttttaa gcggttttca agaccaatat
    49021 tcaactcctt caaggcctct tggaactgga ttctatcctt ctccttcacg ccccaaccaa
    49081 gccctctctt ttgcccacgt ctcaaggcaa tagccatatt ctcctcaatc gtcaaacgag
    49141 aagctgttcc catcttagga tcttgaaaaa cacgggcaat atccttggct ctctttctga
    49201 cactcagatg tttaatggat ttccctgcca gtagaaggtc cccttcgtcc accgatagat
    49261 taccagccaa gatattcatc aaagtggatt ttcctgctcc atttccacca atcacagaga
    49321 taaaatctcc ctcttcaacc tctaaatcta atcctttgag gacatggttc tcattgaccg
    49381 tccctgcttc aaatgtcttg tgaatatttt caagtgttaa caaacttgcc ataactttct
    49441 cctcctattc atttctcaat ttcagaccac gaatctttaa tctcttttgc aatgctggtg
    49501 caaataaaac caaagcgagc aagattgcat taaagagacg taccaagttt tgatctagat
    49561 ttggaatttc atagatattt aaaataatca aacggtaaac aatagcaccg attccgatgg
    49621 ataataagcg gcctccaatg gtcaagtcgt gtatcaagac ttccgagctc aaaccaacaa
    49681 caatggttcc tgtcccagaa gtcacatctg aaaatccatc attttgggca aacaaggaac
    49741 cacatagggc aatcaaaccg gttgaaatca tgtaaccaac aatcttcatg gtgtttacat
    49801 tgactccatt ggcctcactc atcgggatat tgtccccagt cgaacgcaag accaaaccaa
    49861 tctctgtttt catcaaaagg gtcaaaacca aacaagtaag agacagacta aactaagtga
    49921 gaaaacagct ccttcatttg tcagacccaa gctcgccaac tgtttaaaga cggttgcaga
    49981 atctcccaag gaaagattgg gtacactgcc catgatttta atattgattg aatagagccc
    50041 tgtcaaggtc acaatccctg tcaagagagc tgggattttc atcttggtgt ggagcattcc
    50101 tgatataaga cctgctacca tacctgccag caaagcaagt aaagtcgcaa gccaaggatt
    50161 tgcccctgcc tgtatctgtg atacaacgat tgctgccccc ataggaaagg ctccctcagc
    50221 agtcatatcc gcaatatcca aaatacggaa agtcaagtag accccaattg ccataatcga
    50281 ccacaacaaa ccttctgata aactagataa cacaaaattc atcttaatcc tccttattcc
    50341 ttgccttcta acttactaat atcaattcac aatgcatctg ccatttcttg attagtatgc
    50401 aattccagtt tttcaggcaa ctcaactgct atattttctg gttcctcacc ttttaaaaca
    50461 cgaatcagca tgcgagctgt ctgtcttccc aattcttcat aattggttcc gtagttatac
    50521 aagccaccaa cagcaatcat ttctgttgaa ccaccgaata ctggaacctt gtgtttaata
    50581 gaaacctgct taactgtttc catggttgac gaaatgatat tatcagttgg gacaaaaacc
    50641 atatccacct ctgccatcaa actctctgct gccgccttga cgttattact gtccaagatt
    50701 gttttttcaa caacggtaaa gcctttttct ttcagaaatc gcttagcttc atccttttaa
    50761 acaaccgaat tgggctcgct ctgagtatag aggattccaa tcgttttagc ctttagcaac
    50821 actttcttta tcaaattgat ttgggttgaa atggcatctg atgactgatc gcttgtccca
    50881 gttacattgc ccccaggatg ttctcttgac tcaaccaact tggcactgac tgggtctgtt
    50941 acagctgaaa agataactgg tgtcgtttgc gtcgtattgg ccaagctctg agcagaaggc
    51001 cttgcgatgg ctagaacgac atcgctggat tctgctagtt gctgggaaat cgtttttaga
    51061 tttctttgtt ctccctgtgc attttgcaaa tcaatctcaa tattttcccc ctcaacatag
    51121 ccttgtttgg ccagctcatc cacaaatcct tctctagtag cgtctaagga ctggtgggta
    51181 ataaactgcg aaataccgat acgaaagaca tctcttttct tatctgcctt caactgatgc
    51241 aaactgatca gagaagtcaa gaggatcccc actaccaaga gggggctagt gattttcgaa
    51301 caactttcat aatgaaactc cttctcagaa aagataaaac aaaaaaacgc ctagatacta
    51361 tctaaacggg tacttgaaat aacctaacaa gttacaactt agctggtcca tttagatatt
    51421 catctatatg gaccacaatc aaaaatctta gccacataga tacaaacaaa ttgcttgaac
    51481 tgtttgcatc catggtgaca tgtctacaaa cactatctaa agtagctaaa gtaaaagttt
    51541 tgattcatag ttacggcttg tctcttattc atttcttttt ctgctttctt ttttgatcct
    51601 tcctatccta ccaccttttt catcacctgt caataatatt tcaaaatttt ttaaaatttt
    51661 tcgaaaattc tttca
//
LOCUS       DAVBDR010000007        48007 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.007, whole genome shotgun sequence.
ACCESSION   DAVBDR010000007 DAVBDR010000000
VERSION     DAVBDR010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 48007)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48007)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48007
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.007"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            complement(308..1474)
                     /gene="recA"
                     /locus_tag="VQ540_000451"
     CDS             complement(308..1474)
                     /gene="recA"
                     /locus_tag="VQ540_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HET2544312.1"
                     /translation="MAKKPKKLEEISKKFGAEREKALNDALKLIEKDFGKGSIMRLGE
                     RAEQKVQVMSSGSLALDIALGSGGYPKGRIIEIYGPESSGKTTVALHAVAQAQKEGGI
                     AAFIDAEHALDPAYAAALGVNIDELLLSQPDSGEQGLEIAGKLIDSGAVDLVVVDSVA
                     ALVPRAEIDGDIGDSHVGLQARMMSQAMRKLGASINKTKTIAIFINQLREKVGVMFGN
                     PETTPGGRALKFYASVRLDVRGNTQIKGTGDQKETNVGKETKIKVVKNKVAPPFKEAV
                     VEIMYGEGISKTGELLKIASDLDIIKKAGAWYSYKDEKIGQGSENAKKYLAEHPEIFD
                     EIDKQVRSKFGLIDGEEVSEQDTENKKDEPKKEEAVNEEVPLDLGDELEIEIEE"
     gene            complement(1529..2785)
                     /locus_tag="VQ540_000452"
     CDS             complement(1529..2785)
                     /locus_tag="VQ540_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HET2544313.1"
                     /translation="MKAEIIAVGTEILTGQIVNTNAQFLSEKLAEIGVDVYFQTAVGD
                     NEVRLLSLLEIASQRSSLVILTGGLGPTEDDLTKQTLAKFLGKALVFDPQAQEKLDIF
                     FALRPDYARTPNNERQAQIVEGAIPLPNETGLAVGGKLEVDGVTYVVLPGPPSELKPM
                     VLNLLLPKLMTGSKLYSRVLRFFGIGESQLVTILADLIDNQVDPTLAPYAKTGEVTLR
                     LSTKASSQEEANQALDILENQILDCQTFEGISLRDFCYGYGEETSLASIVVEELKRQG
                     KTIAAAESLTAGLFQATVANFSGISSIFKGGFVTYSLEEKSRMLDIPAKNLEEHGVVS
                     EFTAQKMAEQARSKTQSDFGISLTGVAGPDSLEGHPVGTVFIGLAQDQGTEVIKVNIG
                     GRSRADVRHIAVMHAFNLVRKALLSD"
     gene            complement(2869..3885)
                     /locus_tag="VQ540_000453"
     CDS             complement(2869..3885)
                     /locus_tag="VQ540_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HET2544314.1"
                     /translation="MVKKIIGMVLALLSVTVVGVGVFAYTIYQQGTETLAKTYKKIGE
                     ETKVIEATEPLTILLMGVDTGNVERTETWVGRSDSMILMTVNPKTKKTTMMSLERDIL
                     TRIESGNGQAHEAKLNSAYADGGAELAIETIQKMMNIHIDRYVMVNMRGLQKLVDAVG
                     GITVNNILGFPISISDQEEFNTISIGVGEQHIGGEKALVYARMRYQDPEGDYGRQKRQ
                     REVIQKVMEKALSLNSVGHYQEILKALSDNMQTNIDLSAKSIPNLLGYKDSFKTIETQ
                     QLQGEGEILQGVSYQIVSRAHMLEMQNILRRSLGQEEVTQLETNAVLFEDLFGRAPVG
                     DEDN"
     gene            complement(3893..4411)
                     /locus_tag="VQ540_000454"
     CDS             complement(3893..4411)
                     /locus_tag="VQ540_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2544315.1"
                     /translation="MEYELLIREAEPKDAAELVAFLNRVSLETDFTSLDGDGILLTSE
                     EMEIFLNKQASSDNQITLLAFLNGKIAGIVNITADQRKRVRHIGDLFIVIGKRYWNNG
                     LGSLLLEEAIEWAQASGILRRLQLTVQTRNQAAVHLYQKHGFVIEGSQERGAYIEEGK
                     FIDVYLMGKLIG"
     gene            complement(4401..4844)
                     /gene="tsaE"
                     /locus_tag="VQ540_000455"
     CDS             complement(4401..4844)
                     /gene="tsaE"
                     /locus_tag="VQ540_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HET2544316.1"
                     /translation="MYTKNEEELQALGERLGHLLAKNDVLILTGELGAGKTTFTKGLA
                     KGLQISQMIKSPTYTIVREYEGRLPLYHLDVYRIEGDADSIDLDEFIFGGGVTVIEWG
                     NLLGDALPDAYLELEILKEADGRRLNFQAKGLRAEKLLEELQYGV"
     gene            complement(4930..5550)
                     /locus_tag="VQ540_000456"
     CDS             complement(4930..5550)
                     /locus_tag="VQ540_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000839915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2544317.1"
                     /translation="MKSMRILFLLALIQISLSSCFLWKECILSFKQSTAFFIGSMVFV
                     SGICAGVNYLYTRKQEVHSVLASKKSVKLFYSMLLLINLLGAVLVLSDNLFIKNTLQQ
                     ELVDFLLPSFFFLFGLDLLIFLPLKKYVRDFLAMLDRKKTVLVTILATLLFLRNPMTI
                     VSLLIYIGLGLFFAAYLVPNSVKKEVSFYGHIFRDLVLVIVTLIFF"
     gene            complement(5933..6796)
                     /locus_tag="VQ540_000457"
                     /pseudo
     CDS             complement(5933..6796)
                     /locus_tag="VQ540_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093609.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            6961..7155
                     /locus_tag="VQ540_000458"
     CDS             6961..7155
                     /locus_tag="VQ540_000458"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2544318.1"
                     /translation="MKKKRVSRMKKNRGIQKLAILVLLGVFMFSNTIPYQQFIQKNRQ
                     LEIRVQSQKKSNGLDVGKAD"
     gene            7470..7766
                     /locus_tag="VQ540_000459"
     CDS             7470..7766
                     /locus_tag="VQ540_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000911560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HET2544319.1"
                     /translation="MLKFRKVVASSLAVLAFSLALPVLAVSHRGGEWTYGGHHDPNNW
                     GAFSNYYHGSQYHWAYVGSNGRNNQKTVYAGARSAAYAFVNTNFGEQVTFDAGW"
     gene            7869..9884
                     /locus_tag="VQ540_000460"
     CDS             7869..9884
                     /locus_tag="VQ540_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HET2544320.1"
                     /translation="MKKLFILISNLLASLFFVWVFTIWTDTYVSYYYPNVVVHDSSPE
                     TTFQHVATRLEKLAEETDSFIAIQHQDPNSEGTTVFSYTTFGDGKLPDGLQEKKLEDA
                     QSSSVETNYFVFDGHLDIHLLREELSQLGLTNMNLTIPSKLSTLMAIFSNGFQLISLL
                     IFILTFIALTLISQISQLRSSGIRLISGEKRWSIFLRPVGEDLKGIAVGFSLAGVLAI
                     LMQKILSLPTQSLMTIGAGLLSYNLILLSISLFFAQLFAVGIKKIHLMQIIKGQVPVR
                     GIISLILIGQLLAIIIVTLGIGSSLKYSQAWQQHRIGQEAWSQERQLITLSISREGTS
                     PGFDEQAQRKLRTWYQLMDLAVSEQKAFLSRHQLIDRTLQNGMASSKNLITSTEWHDY
                     NPNGNVLIVTPQYLERQNIPVDTTIEQKMNHLDVGEFVLLLPEHLRSEEEHYKSVFED
                     DLTSRMSSQDERQQMTATVGYLESGQDRFVYNTTPISYQQFLKDPIIIVITPQSTGPQ
                     SILFWIDAVQNYVLFNQLSDAQELIQRQGIENWVSEMQTGYHNYITLLDNIQRERWVM
                     LAGAGLGIATSILLFNTMNRLYFEEFRRAIFIKRIAGLRFLEIHRTYLFAQLGVFLLG
                     FVASVFLQVEIGVAFLVLLLFTGLSLLQLHVQMQKENKMSMLVLKGG"
     gene            9886..10518
                     /locus_tag="VQ540_000461"
     CDS             9886..10518
                     /locus_tag="VQ540_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2544321.1"
                     /translation="MIELKQVSKSFGERELFSNLSMTFEAGKVYALIGSSGSGKTTLM
                     NMIGKLEPYDGTIFYRGKDLANYKSSDFFRHELGYLFQNFGLIENQSIEENLKLGLIG
                     QKLSRSEQRLRQKQALEQVGLTYLDLDKRIFELSGGESQRVALAKVILKNPPFILADE
                     PTASIDPATSQLIMEILLSLRDDNRLIIIATHNPAIWEMADEVFTMDRLK"
     gene            10659..10937
                     /locus_tag="VQ540_000462"
     CDS             10659..10937
                     /locus_tag="VQ540_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComA"
                     /protein_id="HET2544322.1"
                     /translation="MKKFDNYIVEKPCDSNSDKLQKILIIENLVDDILQFPLRINNSV
                     GEIFLLQPFQKKTIFIPCYFEEDIVKVKDDDKVEWNLLEFQKFRAFLA"
     gene            complement(11446..11859)
                     /gene="ndk"
                     /locus_tag="VQ540_000463"
     CDS             complement(11446..11859)
                     /gene="ndk"
                     /locus_tag="VQ540_000463"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000438285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HET2544323.1"
                     /translation="MEQTFFIIKPDGVKRGLVGEVLKRIEQRGFTIEKLEFRSQVSEE
                     LIDQHYQDLVGQSFYPPIREFMTSGPVLVGVISGPKVIETWRTMMGATRPEEALPGTI
                     RGDFAKAAGENEVIQNVVHGSDSEESAKREIALWF"
     gene            complement(11970..15647)
                     /gene="rpoC"
                     /locus_tag="VQ540_000464"
     CDS             complement(11970..15647)
                     /gene="rpoC"
                     /locus_tag="VQ540_000464"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000228741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HET2544324.1"
                     /translation="MVDVNRFKSMQITLASPSKVRSWSYGEVKKPETINYRTLKPERE
                     GLFDEVIFGPTKDWECACGKYKRIRYRGIVCDRCGVEVTRTKVRRERMGHIELKAPVS
                     HIWYFKGIPSRMGLTLDMSPRALEEVIYFAAYVVIDPKDTPLEHKSIMTEREYRERLR
                     EYGYGSFVAKMGAEAIQDLLKQVDLEKEIAELKEELKTATGQKRVKAIRRLDVLDAFY
                     KSGNKPEWMILNILPVIPPDLRPMLQLDGGRFASSDLNDLYRRVINRNNRLARLLELN
                     APGIIVQNEKRMLQEAVDALIDNGRRGRPITGPGSRPLKSLSHMLKGKQGRFRQNLLG
                     KRVDFSGRSVIAVGPTLKMYQCGVPREMAIELFKPFVMREIVARDIVQNVKAAKRLVE
                     RGDERIWDILEEVIKEHPVLLNRAPTLHRLGIQAFEPVLIDGKALRLHPLVCEAYNAD
                     FDGDQMAIHVPLSEEAQAEARILMLAAEHILNPKDGKPVVTPSQDMVLGNYYLTMEEA
                     GREGEGMVFKDRDEAVMAYRNGYVHLHSRVGIATDSLNKPWTEEQRHKVLLTTVGKIL
                     FNDIMPEGLPYLQEPNNANLTEGVPAKYFLPLGGDIKEAISNLELNPPFKKKNLGNII
                     AEIFKRFRTTETSALLDRMKNLGYHHSTLAGLTVGIADIPVVDDKAEIIEESHKRVEQ
                     ITKQFRRGMITDDERYNAVTAEWRAAREKLEKRLIANQDPKNPIVMMMDSGARGNISN
                     FSQLAGMRGLMAAPNGRIMELPILSNFREGLSVLEMFFSTHGARKGMTDTALKTADSG
                     YLTRRLVDVAQDVIIREDDCGTDRGLLIRSIAEGKEMIESLEERLNGRYTKKTVKHPE
                     TGAVIIGPNELITEDKAREIVNAGVEEVTIRSVFTCNTRHGVCRHCYGINLATGDAVE
                     VGEAVGTIAAQSIGEPGTQLTMRTFHTGGVASNTDITQGLPRVQEIFEARNPKGEAVI
                     TEVKGEVTAIEEDASTRTKKVFVKGETGEGEYVVPFTARMRVEVGGQVARGAALTEGS
                     IQPKRLLAVRDVLSVETYLLGEVQKVYRSQGVEIGDKHIEVMVRQMIRKVRVMDPGDT
                     DLLMGTLMDINDFTDANKDVLIAGGVPATGRPVLMGITKASLETNSFLSAASFQETTR
                     VLTDAAIRGKKDHLLGLKENVIIGKIIPAGTGMARYRNLEPYAVNEEEYLNPPVEEEG
                     NEETTEVVVDTAVETVEETVE"
     gene            complement(15680..19291)
                     /gene="rpoB"
                     /locus_tag="VQ540_000465"
     CDS             complement(15680..19291)
                     /gene="rpoB"
                     /locus_tag="VQ540_000465"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000907130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HET2544325.1"
                     /translation="MAGHDVQYGKHRTRRSFSRIKEVLDLPNLIEIQTDSFKAFLDHG
                     LKEVFEDVLPISNFTDTMELEFVGYEIKEPKYTLEEARIHDASYSAPIFVTFRLINKE
                     TGEIKTQEVFFGDFPIMTEMGTFIINGGERIIVSQLVRSPGVYFNDKVDKNGKVGYGS
                     TVIPNRGAWLELESDSKDITYTRIDRTRKIPFTTLVRALGFSGDDEIFDIFGDSELVR
                     NTVEKDIHKNPMDSRTDEALKEIYERLRPGEPKTAESSRSLLVARFFDPRRYDLAAVG
                     RYKINKKLNVKTRLLNQTIAEPLVDPETGEILVEAGTIMTRSVIESIESHLDGDLNKI
                     VYIPNDAAVVTEPVVLQKFKVVAPTDPDRVVTIIGNANPDDKVRTVTPADILAEMSYF
                     LNLAEGLGRVDDIDHLGNRRIRAVGELLANQVRLGLSRMERNVRERMSVQDNEVLTPQ
                     QIINIRPVTAAVKEFFGSSQLSQFMDQHNPLSELSHKRRLSALGPGGLTRDRAGYEVR
                     DVHYTHYGRMCPIETPEGPNIGLINNLSSYGHLNKYGFVQTPYRKVDRETGVVTNEIV
                     WLTADEEDEYTVAQANSSLNEDGTFAEKIVMGRHQGVNQEYPANIVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPYVGTGMEYQAAHDSGAAVIAQY
                     DGKVTYADADKVEVRREDGSLDVYHIQKFRRSNSGTAYNQRTLVKVGDVVEKGDFIAD
                     GPSMENGEMALGQNPIVAYMTWEGYNFEDAVIMSERLVKDDVYTSVHLEEYESETRDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVKEGDILVGKVTPKGEKDLSAEERL
                     LHAIFGDKSREVRDTSLRVPHGADGVVRDVKIFTRVNGDELQSGVNMLVRVYIAQKRK
                     IKVGDKMAGRHGNKGVVSRIVPVEDMPYLPDGTPVDIMLNPLGVPSRMNIGQVMELHL
                     GMAARTLGIHIATPVFDGASSEDLWSTVKEAGMDSDAKTILYDGRTGEPFDNRVSVGV
                     MYMIKLHHMVDDKLHARSVGPYSTVTQQPLGGKAQFGGQRFGEMEVWALEAYGASNVL
                     QEILTYKSDDINGRLKAYEAITKGKPIPKPGVPESFRVLVKELQSLGLDMRVLDEDDQ
                     EVELRDLDEGMDEDVIHVDDLEKAREKAAQEAKAAFEAEEAEKATKAEATEEAAEQE"
     gene            19707..19777
                     /locus_tag="VQ540_000466"
     tRNA            19707..19777
                     /locus_tag="VQ540_000466"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:19739..19741,aa:Cys,seq:gca)
     gene            complement(19975..21306)
                     /locus_tag="VQ540_000467"
     CDS             complement(19975..21306)
                     /locus_tag="VQ540_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HET2544326.1"
                     /translation="MEDPSSQNLLLQFVLLFILTVLNAFFSATEMAMVSLNRARVEQK
                     AEEGDRRYIRLLKVLENPNHFLSTIQVGITLITILSGASLTDTLGRVIASWLGNGETA
                     QAVATFLSLAFLTYISIVFGELYPKRIALNLKDALAIRTAPVIIGIGKLVSPFVWLLA
                     ASTNFLSHLTPMSFDDADEKMTRDEIAYMLTNSEETLDADEIEMLQGVFSLDELMARE
                     VMVPRTDAFMVDIQDDSQAIIQSILKQNYSRIPVYDGDKDNVIGIIHTKSLLKAGFVD
                     GFDNIVWKRILQDPLFVPETIFVDDLLKELRNTQRQMAILLDEYGGMAGLVTLEDLLE
                     EIVGEIDDETDKAAIDVHQIGEDTYIVQGTMTLNDFNNYFNVELESDDVDTIAGYYLT
                     GVGTIPTTEKLSYELVSQNKQFILTNDKVKNGRVTKVKVQITEVEIEEETE"
     gene            complement(21597..22421)
                     /gene="endA"
                     /locus_tag="VQ540_000468"
     CDS             complement(21597..22421)
                     /gene="endA"
                     /locus_tag="VQ540_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-entry nuclease EndA"
                     /protein_id="HET2544327.1"
                     /translation="MNKKTRQTLIGLLVLLLLSTGSYYIKQMQSTANSPKTKLSQKKQ
                     APEAPSQALAESVLTDAVKSQIKGSLEWNGSGAFIVNGNKTNLDAKVSSKPYADNKTK
                     TVGKETVPTVANALLSKATRQYKNRKETGNGSTSWTPPGWHQVKNLKGSYTHAVDRGH
                     LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEYSTGQNYYESKVRKALDQNKRV
                     RYRVTLYYASNEDLVPSASQIEAKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ"
     gene            complement(22460..22648)
                     /locus_tag="VQ540_000469"
     CDS             complement(22460..22648)
                     /locus_tag="VQ540_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HET2544328.1"
                     /translation="MNKKSSYVVKRLLLVIIVLILGTLALGIGLMVGYGILGKGQDSW
                     AILSPAKWQELIHKFTGN"
     gene            complement(22641..23924)
                     /gene="murA"
                     /locus_tag="VQ540_000470"
     CDS             complement(22641..23924)
                     /gene="murA"
                     /locus_tag="VQ540_000470"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HET2544329.1"
                     /translation="MDKIVVQGGDNRLVGSVTIEGAKNAVLPLLAATILASEGKTVLQ
                     NVPILSDVFIMNQVVGGLNAKVDFDEEAHLVKVDATGDITEEAPYKYVSKMRASIVVL
                     GPILARVGHAKVSMPGGCTIGSRPIDLHLKGLEAMGVKISQTAGYIEAKAERLHGAHI
                     YMDFPSVGATQNLMMAATLADGVTVIENAAREPEIVDLAILLNEMGAKVKGAGTETIT
                     ITGVEKLHGTTHNVVQDRIEAGTFMVAAAMTGGDVLIRDAVWEHNRPLIAKLLEMGVE
                     VIEEDEGIRVRSQLENLKAVHVKTLPHPGFPTDMQAQFTALMTVAKGESTMVETVFEN
                     RFQHLEEMRRMGLHSEIIRDTARIVGGQPLQGAEVLSTDLRASAALILTGLVAQGETV
                     VGKLVHLDRGYYGFHEKLAQLGAKIQRIEASDEDE"
     gene            complement(23948..24178)
                     /locus_tag="VQ540_000471"
     CDS             complement(23948..24178)
                     /locus_tag="VQ540_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014017351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HET2544330.1"
                     /translation="MVQLLFTLSSHMLFIYVSFYLLKDLVRWEKVLKVTAENTRKVRV
                     LVAFFSIVIGYILSSFFISLYHLWQEALRGLL"
     gene            complement(24236..25273)
                     /locus_tag="VQ540_000472"
     CDS             complement(24236..25273)
                     /locus_tag="VQ540_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HET2544331.1"
                     /translation="MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLK
                     VNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFTDIRSAQETTGGSSDVEFMRINQ
                     FYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
                     DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVIS
                     NVPISFSTAGIGGPSAGLMFSLAIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGID
                     KKVVASARAGAAIFFAPDNPVSEEEQKAHPDAKNNYQTALEAAKTIKTDMKIVPVKTL
                     QDAIDYLKNNP"
     gene            complement(25257..25745)
                     /gene="coaD"
                     /locus_tag="VQ540_000473"
     CDS             complement(25257..25745)
                     /gene="coaD"
                     /locus_tag="VQ540_000473"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HET2544332.1"
                     /translation="MSDKIGLFTGSFDPMTNGHLDIIERASRLFDKLCVGIFFNPHKQ
                     GFLPLENRKRGLEKALGHLENVEVVASHDELVVDVAKRLGATCLVRGLRNASDLQYEA
                     SFDYYNHQLSSDIETIYLHSRPEHLYISSSGVRELLKFGQDIACYVPESILEEIRNEK
                     KD"
     gene            complement(25735..26274)
                     /gene="rsmD"
                     /locus_tag="VQ540_000474"
     CDS             complement(25735..26274)
                     /gene="rsmD"
                     /locus_tag="VQ540_000474"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HET2544333.1"
                     /translation="MKIVSGIYGGRPLKTLEGKTTRPTSDKVRGAIFNMIGPYFEVGR
                     VLDLYAGSGGLSIEAVSRGMSSAVLVERDRKAQTIVAENIQMTKEVGKFQLLKMDAER
                     ALEQVSGEFDLVFLDPPYAKEQIVADIEKMAERELFSEDVMVVCETDKTVELPEEIAC
                     LGIWKEKIYGISKVTVYVR"
     gene            complement(26339..27331)
                     /locus_tag="VQ540_000475"
     CDS             complement(26339..27331)
                     /locus_tag="VQ540_000475"
                     /EC_number="6.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016502595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
                     /protein_id="HET2544334.1"
                     /translation="MKKSFIHQQEEISFVKNTFTQYLKDKLEVVEVQGPILSKVGDGM
                     QDNLSGVENPVSVKVLQIPDATYEVVHSLAKWKRHTLARFGFGEGEGLFVHMKALRPD
                     EDSLDATHSVYVDQWDWEKVIPNGKRNIVYLKETVEKIYKAIRLTELAVEARYDIESI
                     LPKQITFIHTEELVERYPDLTPKERENAICKEFGAVFLIGIGGELPDGKPHDGRAPDY
                     DDWTSESENGYKGLNGDILVWNESLGGAFELSSMGIRVDEETLRRQVEITGDEDRLEL
                     EWHKSLLNGLFPLTIGGGIGQSRMAMFLLRKRHIGEVQTSVWPQEVRDTYENIL"
     gene            complement(27443..28126)
                     /locus_tag="VQ540_000476"
     CDS             complement(27443..28126)
                     /locus_tag="VQ540_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HET2544335.1"
                     /translation="MNHTIIHDRAGLNQFYAKVYAFVGLGIGLSALVSGLMLTVFQSQ
                     LVYLLMQGRLWLTIATFAELALVFVASSMASRNSPAALPVFLLYSVLNGFTLSFVVAF
                     YTPGTVLSAFVSSALLFFVMAAVGIFTKKDLSGIGRAMMAALIGLLIAMVVNIFLASG
                     FFDYMISVAMVLVFSGLIAWDNQKIRLAYEQSQGRVATGWVVSMALSIYLDFINLFLS
                     ILRIFGRND"
     gene            complement(28182..28922)
                     /locus_tag="VQ540_000477"
     CDS             complement(28182..28922)
                     /locus_tag="VQ540_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HET2544336.1"
                     /translation="MTIITSKANSVVKNAKKLHQKKYRKSAYLIEGWHLFEEAVQAGV
                     TIEKIFALENYRNQLAAFPQTVWISEDILLDLADSQTPQGIVAVVQKEEVGQADLSQG
                     KFLFLEDVQDPGNVGTIIRTADAAGFTGVIVSDKSADIYSLKTLRSMQGSHFHLPIYR
                     MTSQALLDETKKVAIPVLATTLSKDSVDYRELPSIENFVLVMGNEGQGISPLMAESAD
                     QLVHISMKGQAESLNVAVAAGILIFHLS"
     gene            28956..29234
                     /locus_tag="VQ540_000478"
     CDS             28956..29234
                     /locus_tag="VQ540_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001174612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HET2544337.1"
                     /translation="MQKVRMIAQGRVQGVGFRWGVYSLALEIGGITGRVWNNDDGTVE
                     ILAQADSSAIMAKFIQEIRKGPTPFSKVSYLDVKLSNFPPYSDFKIAN"
     gene            29312..30238
                     /gene="yidC"
                     /locus_tag="VQ540_000479"
     CDS             29312..30238
                     /gene="yidC"
                     /locus_tag="VQ540_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HET2544338.1"
                     /translation="MKSIKRFAFSAMGVAMLLVLTGCVNVDKTTGQPTGFIWNTIGAP
                     MAEAIKYFATDKGLGFGVAIIIVTIIVRLIILPLGIYQSWKATLHSEKMNALKHVLEP
                     HQTRLKEATTQEEKLEAQQALFAAQKEHGISMFGGVGCFPILLQMPFFSAIYFAAQHT
                     EGVAQASYLGIPLGSPSMILVACAGVLYYLQSLLSLHGVEDEMQREQIKKMIYMSPLM
                     IVVFSLFSPASVTLYWVVGGFMMILQQFIVNYIVRPKLRKKVREELAKNPPKASAFSK
                     PSGRKDVTPEQPTAITSKKKHKNRNAGKQRSR"
     gene            complement(30313..31107)
                     /gene="pflA"
                     /locus_tag="VQ540_000480"
     CDS             complement(30313..31107)
                     /gene="pflA"
                     /locus_tag="VQ540_000480"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001288284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HET2544339.1"
                     /translation="MSEETIDYGQVTGMVHSTESFGSVDGPGIRFIVFLQGCHMRCQY
                     CHNPDTWAMESNKSRERTVDDVLTEALRYRGFWGNKGGITVSGGEALLQIDFLIALFT
                     KAKEQGIHCTLDTCALPFRNKPRYLEKFDKLMAVTDLVLLDIKEINEEQHKIVTSQTN
                     KNILACAQYLSDIGKPVWIRHVLVPGLTDRDDDLIELGKFVKTLKNVDKFEILPYHTM
                     GEFKWRELGIPYSLEGVKPPTADRVKNAKKLMDTESYQDYMKRVHG"
     gene            complement(31233..32483)
                     /locus_tag="VQ540_000481"
     CDS             complement(31233..32483)
                     /locus_tag="VQ540_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000856498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HET2544340.1"
                     /translation="MKTPFINREELEAIVAEFPTPFHLYDEKGIREKARAVNQAFSWN
                     KGFKEYFAVKATPTPAILKILQEEGCGVDCSSYVELLMSHKLDFLGSEIMFSSNNTPD
                     KEYAYARELGATINLDAFEDIEHLERVAGIPEIISCRYNPGGVFELGTDIMDNPGEAK
                     FGMTKDQLFEAFAILKEKGAKTFGIHSFLASNTVTHLYYPELARQLFELAVEIKEKLG
                     ISLDFINLSGGIGVNYRPDQEPNDIALIGEGVRKVYEEVLTSAGLGQVKIFTELGRFM
                     LAPHGALVTRVTHKKETYRTYLGVDASAVNLMRPAMYGAYHHISNVTHPDGPAEAVDV
                     VGSLCENNDKFAVNRELPHTEIGDLLVIHDTGAHGFSMGYQYNAKLRSAEILYTEEGK
                     ARQIRRAERPEDYFATLYGFDFEE"
     gene            complement(32550..33377)
                     /gene="purR"
                     /locus_tag="VQ540_000482"
     CDS             complement(32550..33377)
                     /gene="purR"
                     /locus_tag="VQ540_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004242125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HET2544341.1"
                     /translation="MKLRRSDRMVVISNYLINNPYKLTSLNTFAEKYESAKSSISEDI
                     VIIKRAFEEIEIGHIQTVTGAGGGVIFTPSISSQDAKEMVEDLRTKLSESDRILPGGY
                     IYLSDLLSTPAILKNIGRIIAKSFMDQKIDAVMTVATKGVPLANAVANVLNVSFVIVR
                     RDLKITEGSTVSVNYVSGSSGDRIEKMFLSKRSLKAGSRVLIVDDFLKGGGTVNGMIS
                     LLHEFDSELAGVAVFADNAQEEREKQFDYKSLLKVTNIDVKNQAIDVEVGNIFDEDK"
     gene            complement(33644..34585)
                     /locus_tag="VQ540_000483"
     CDS             complement(33644..34585)
                     /locus_tag="VQ540_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exoribonuclease YhaM family protein"
                     /protein_id="HET2544342.1"
                     /translation="MKISHMKKDELFEGFYLIKSADLRQTRAGKNYLAFTFQDDSGEI
                     DGKLWDAQPHNIEAFTAGKVVHMKGRREVYNNTPQVNQITLRLPQAGEPNDPADFKVK
                     SPVDVKEIRDYMSQMIFKIENPVWQRIVRNLYTKYDKEFYSYPAAKTNHHAFETGLAY
                     HTATMVRLADAISEVYPQLNKSLLYAGIMLHDLAKVIELTGPDQTEYTVRGNLLGHIA
                     LIDSEITKTVMELGIDDTKEEVVLLRHVILSHHGLLEYGSPVRPRIMEAEIIHMIDNL
                     DASMMMMSTALALVDKGEMTNKIFAMDNRSFYKPDLD"
     gene            complement(34575..35831)
                     /locus_tag="VQ540_000484"
     CDS             complement(34575..35831)
                     /locus_tag="VQ540_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombination protein RmuC"
                     /protein_id="HET2544343.1"
                     /translation="MESLLILLLIANLAGLFLIWQRQDRQEKHLSKSLEDQADHLSDQ
                     LDYRFDQARQASQLDQKDLEVVVSDRLQEVRIELHQGLTQVRQEMTDNLLQTRDKTDQ
                     RLQALQESNEQRLEQMRQTVEEKLEKTLQTRLQASFETVSKQLESVNRGLGEMQTVAR
                     DVGALNKVLSGTKTRGILGELQLGQIIEDIMTPAQYEREYATVENSSERVEYAIKLPG
                     QGDQEYVYLPIDSKFPLADYYRLEEAYETGDKDEIERCRKSLLASVKRFARDIRNKYI
                     APPRTTNFGILFVPTEGLYSEIVRNPVFFDDLRREEQIIVAGPSTLSALLNSLSVGFK
                     TLNIQKSADHISKTLASVKTEFGKFGGILVKAQKHLQHASGNIDELLNRRTIAIERTL
                     RHIELSEGEPALDLLHFQENEEEYED"
     gene            complement(35833..36495)
                     /locus_tag="VQ540_000485"
     CDS             complement(35833..36495)
                     /locus_tag="VQ540_000485"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000006147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HET2544344.1"
                     /translation="MSEYKLSENNWTRVAVFAGGDRGHYRTDFDGFVGVDRGSLWILE
                     EDLPLALAVGDFDSVTEEERQVIQKRAQYFVQARPEKDDTDLELALLTIFKQNPQAQV
                     TIFGALGGRIDHMLANVFLPSNPKLASYMHQIEIEDGQNLITYCPEGISQLEPRSDYD
                     YLAFMPVRDSQLTILGAKYELTEENFFFKKVYASNEYIDREVSVTCPDGYVVVLHSKD
                     RR"
     gene            complement(36458..37114)
                     /locus_tag="VQ540_000486"
     CDS             complement(36458..37114)
                     /locus_tag="VQ540_000486"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HET2544345.1"
                     /translation="MSQYKIAPSILAADYANFEREIKRLEATGAEYAHIDIMDGHFVP
                     QISFGAGVVEALRPHSKMVFDCHLMVSNPEHHLEDFVRAGADIISIHVEATPHIHGAL
                     QKIRSLGVKPSVVINPGTPVEAIKHVLHLVDQVLVMTVNPGFGGQAFLPETMDKVREL
                     VALRDEKGLNFEIEVDGGIDDQTIAQAKEAGATVFVAGSYVFKGDVNERVQTLRKQLD
                     "
     gene            complement(37125..38003)
                     /gene="rsgA"
                     /locus_tag="VQ540_000487"
     CDS             complement(37125..38003)
                     /gene="rsgA"
                     /locus_tag="VQ540_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HET2544346.1"
                     /translation="MQGQIIKALAGFYYVESDGQVYQTRARGNFRKKGHTPYVGDWVD
                     FSAEENSEGYILKIHERKNSLVRPPIVNIDQAVVIMSVKEPDFNSNLLDRFLVLLEHK
                     GIHPIVYISKMDLLEDGGELDFYQQTYGDIGYDFVTSKEELLPLLTGKVTVFMGQTGV
                     GKSTLLNKIAPDLNLETGEISDSLGRGRHTTRAVSFYNLNGGKIADTPGFSSLDYEVS
                     TAEDLNQAFPEIATVSRDCKFRTCTHTHEPSCAVKPAVEEGTIAPFRFDNYLQFLSEI
                     ENRRETYKKVSKKIPK"
     gene            complement(38596..39369)
                     /locus_tag="VQ540_000488"
     CDS             complement(38596..39369)
                     /locus_tag="VQ540_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell surface protein"
                     /protein_id="HET2544347.1"
                     /translation="MRKKLVNSLMCAVVLSGFPIATYANEKNIGPNITVSNGQTRLSI
                     PEKNGVEVIQSEENRVVYEVKEAAKIETSDGDMVAPIVVDSRITSINNQVVQGKTVYT
                     ADLEKATFVEEGYNKLAKPTNILDHIFGIQKVHAYTQNITTHQSQFDSTYSVELYTVV
                     HWVSYDGGVQKNITKISGGVDFHERDIEIESSSVEVRQGGWYSSQQKWFHPGARSSWE
                     YSTGFSKVGPGENRVVTNYTVNLIRYGDRWSAYLQNNPW"
     gene            complement(40059..40931)
                     /gene="rsmA"
                     /locus_tag="VQ540_000489"
     CDS             complement(40059..40931)
                     /gene="rsmA"
                     /locus_tag="VQ540_000489"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HET2544348.1"
                     /translation="MRIADYSVTKAVLERHGFTFKKSFGQNFLTDTNILQKIVDTAEI
                     DDQVNVIEIGPGIGALTEFLAERAAEVMAFEIDHRLVPILADTLRDFDNVTVVNEDIL
                     KVDLAQHIQNFKNPDLPIKVVANLPYYITTPILMHLIESGIPFSEFVVMMQKEVADRI
                     SAQPNTKAYGSLSIAVQYYMTAKVAFIVPRTVFVPAPNVDSAILKMVRRPVPAVAVED
                     ENFFFKVSKASFTHRRKTLWNNLTGYFGKTEEVKDKLTKALDQAGLSPSVRGEALSLE
                     EFASLADALKGQGL"
     gene            complement(41182..41400)
                     /locus_tag="VQ540_000490"
     CDS             complement(41182..41400)
                     /locus_tag="VQ540_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2544349.1"
                     /translation="MENMTNPLLLVQIRVHGYLLDFASSEGQRQKHYRLKNLPQTVEL
                     TVDDVEEDVDLTLPENRSYQEADFFDTQ"
     gene            complement(41468..42109)
                     /locus_tag="VQ540_000491"
     CDS             complement(41468..42109)
                     /locus_tag="VQ540_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2544350.1"
                     /translation="MIDIQGLEKKFNDRAIFSGLNLKLEKGKVYALIGKSGSGKTTLL
                     NILGKLEKIDGGRVLYQGKDLKTIPTREYFRDQMGYLFQNFGLLENQSIKENLDLGFV
                     GQKISKVERLERQVGALEKVNLGYLDLEQKIYTLSGGEAQRVALAKTILKNPPLILAD
                     EPTAALDPENSEEVMNLLVDLKDENRIIIIATHNPLVWNKADEIIDMRKLAHV"
     gene            complement(42111..44141)
                     /locus_tag="VQ540_000492"
     CDS             complement(42111..44141)
                     /locus_tag="VQ540_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000825281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HET2544351.1"
                     /translation="MKRLFILISMVLVSLYMVITSVDHREEILFGNYPSVDVTGMMIN
                     QPVASREEVTEVLSHLAVEHNSLIARRIVEPNEAGETLFTYATYGEGELPEGLTISSK
                     ESAETSDLLGSYLIVSGSLDGVSLQTTLKELGYQGFVSNGEDPFSIVLLLAATPMVLL
                     SLAIFLLTFMSLTLIYRIKSLRQAGIRLIAGESLFGVALRPVLEDVRQFICSVLVSSL
                     LGLGILWYQGALFMATVQLVIIALLLYGLTLAGISTLLSVVYLLGLQENSLVDLLKGK
                     LPLKRMMTLMMVGQLLAVLVVGSSATALLPHYREMQEMERASNKWSQSSDRYRLSFGW
                     SSAFADEEGTRKDNREWQTFTEERLANTDSFYIMSNVDNFSDGAEVDLDGNRLSDYTP
                     SGNVIYVSPRYLIEEKITVSSEFMDKMQNLSEGEFGLILPESLREQSTYYQRLFTDYL
                     QNFSSESVEVTSQKYYLPQVSLAFTETGQERFLYNDGYKTTRQYLKDPIIVVLTPQAT
                     GTRPVAGMLWGTTANSALKLDRYGDSITALKEQGLYHKVSYLVKSQLFFAKVLNDKRV
                     EFYSLLIGTILTLSTAILLFDSMNLLYFEQFRRELMIKRLAGMTIYELHGKYLLAQGG
                     VLLLGLVLSSILTRDGLISALVVALFTLNALLILVRQDKKEEAGSMAVLKGK"
     gene            complement(44410..45309)
                     /locus_tag="VQ540_000493"
     CDS             complement(44410..45309)
                     /locus_tag="VQ540_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET2544352.1"
                     /translation="MLIGQKIKEIRIEKGVSRPYFCGDEQELTVRQLSRIESGASQPS
                     LPKLAYIARRLGVPVYSLMPDFSALPPAYLELKYQILREPIYGKEEEYDKKEACLEEI
                     YKTYFDNLPKEEQLACEVLQACLDTSRTRRPEYAELILEEHMSQIIEKEVYSTNDMLL
                     IRLFFYQMLIRKDLAKFINQIEKLMLFLLEQKKVTKLENFFIIRDTLISGMCCLEKVG
                     VTDCFNDYLSCLQEIMDKTQDYQKKPLVFMFLWKQALREERDFSLAESFYQSSKTFAK
                     LIGDGFLVKKLTEEWQEDVKKYL"
     gene            complement(45381..45941)
                     /gene="rnmV"
                     /locus_tag="VQ540_000494"
     CDS             complement(45381..45941)
                     /gene="rnmV"
                     /locus_tag="VQ540_000494"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HET2544353.1"
                     /translation="MKEKISQVIVVEGRDDTVNLKRYFDVETYETRGSAINAQDIERI
                     QRLHQRHGVIVFTDPDFNGERIRRMIMTAIPTVRHAFLKRDEAVPKSKTKGRSLGIEH
                     ASYEDLKTALAQVTEQFEHESQFDISRSDLIRLGFLAGADSRKRREYLGETLRIGYSN
                     GKQLLKRLELFGVTLAEVEEAMKSYE"
     gene            complement(45941..46714)
                     /locus_tag="VQ540_000495"
     CDS             complement(45941..46714)
                     /locus_tag="VQ540_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HET2544354.1"
                     /translation="MIFDTHTHLNVEEFAGREAEEIALAAEMGVTQMNIVGFDKPTIE
                     RALELVDEYDQLYATIGWHPTEAGTYTEEVEAYLLDKLKHPKVVALGEIGLDYHWMTA
                     PKEVQEQVFRRQIQLSKDLDLPFVVHTRDALEDTYEIIKSEGVGPRGGIMHSFSGTLE
                     WAEKFVDLGMTISFSGVVTFKKVTDLQEAAKELPLDKILVETDAPYLAPVPKRGRENK
                     TAYTRYVVDFIADLRGMTTEELAVATTANAERIFGLDSK"
     gene            complement(47019..47912)
                     /locus_tag="VQ540_000496"
     CDS             complement(47019..47912)
                     /locus_tag="VQ540_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1542 domain-containing protein"
                     /protein_id="HET2544355.1"
                     /translation="MVAQDPKAQDSTKPTAEKSTVKAPAQRVDVKDITHLTDEEKVKV
                     AILQANGSALDGATINVAGDGTATITFPDGSVVTILGKDTVQQSAKGESVTQEATPEY
                     KLENTPGGDKGGNTGSSDANANAGGGSQAGGSAHTGSQNSAQSQASKQLATEKESAKN
                     AIEKAAKDKQDEIKGAPLSDKEKAELLARVEAEKQAALKEIENAKTMEDVKEAETIGV
                     QAIVMVTVPKRPVAPNAAPKTTSAPQATAGTMQDVTYQSPAGKQLPNTGSASSAALAS
                     LGLVVATSGFALLGRKTRRRK"
BASE COUNT        13856 a        10819 c         8962 g        14370 t
ORIGIN      
        1 taaagctatt atatcagctt tccagaggag cgacaagaaa cagcaaactt atatatagcg
       61 gaatgaaata aggaaagtca aatcgatttt taacaatgtt ttagaagtag atatgtacta
      121 ttctagtttc gatctattat agttggttga gtttggaata gtacgctgta gctgctaaaa
      181 catttctaga aattaatttg actttcctaa tagagttgtt catatcttat ttcaagctac
      241 tatatataat ctaaaaactt gaatcaaaaa tcgaaaaagt agcggatttc tccactgctt
      301 taacagctta ttcttcaatt tcgatttcaa gttcatcgcc taagtcaagc ggaacttctt
      361 cattcactgc ttcttctttc tttggctcat cttttttgtt ttcagtatct tgttctgaaa
      421 cttcttctcc atcaatcaag ccaaatttag aacggacttg cttatcaatt tcatcaaaga
      481 tttctgggtg ctctgccaag tatttcttag cattctcaga accttgccca attttttcat
      541 ctttgtaaga ataccaagcc cctgcttttt tgataatatc caaatcgctt gcaatcttca
      601 aaagctcacc agtcttagaa attccttctc cgtacataat ttcaactacg gcttccttaa
      661 acggtggagc taccttattt tttacaacct taatcttagt ttctttaccg acattggttt
      721 ctttttggtc accagttccc ttaatttgtg tattaccacg aacatccaag cggactgaag
      781 catagaattt caaagcacgt ccgcccggtg ttgtttctgg atttccaaac atcactccaa
      841 ctttttcacg caattggttg ataaaaatgg caattgtttt ggttttattg atagaggcgc
      901 caagtttacg catggcctgg ctcatcatac gagcctgcaa accaacatgg ctatctccga
      961 tatctccatc aatttccgca cgaggaacaa gggcagcaac tgagtcgact acgacaagat
     1021 caactgcacc tgagtcaatc aattttcccg caatctcaag accttgctct cctgagtctg
     1081 gttgagacaa gagcaattcg tcaatattga caccaagggc cgcagcataa gctggatcaa
     1141 gggcatgttc cgcatcgata aaagcagcaa tcccaccttc tttttgcgct tgtgcaactg
     1201 catgaagggc aaccgttgtc ttaccagatg actctgggcc atagatttcg atgatacgtc
     1261 ccttaggata accacctgag ccaagggcaa tgtcaagagc taaagaacct gagctcatca
     1321 cttgcacctt ttgctccgca cgttcaccca aacgcatgat tgatccttta ccaaagtctt
     1381 tctcaatcaa tttaagagcg tcattcaagg ccttttcacg ttctgcccca aatttttttg
     1441 aaatttcttc taattttttt ggttttttcg ccattctatt ctcctacatt ctaatgatcc
     1501 tcagacctat ctactattat atcaaaaatt agtcacttaa taaagccttg cgaactaggt
     1561 taaaggcatg cataaccgca atgtgacgta catctgctcg gcttctgcct ccaatattaa
     1621 ccttgataac ctcagttcct tgatcttgcg ccaagcctat gaagactgtc ccaactgggt
     1681 gtccttctag gctatctggt cctgccactc cagtcaaact aattccaaaa tcagactggg
     1741 tcttgcttcg tgcctgctca gccatcttct gagctgtaaa ttcagacacc acaccatgtt
     1801 cttccaaatt cttggcagga atatccaaca tccttgattt ttcctccaag ctataggtca
     1861 caaaaccacc cttaaatata cttgaaattc cagaaaaatt cgccacggta gcttggaaaa
     1921 gacctgccgt caaactctct gcagccgcga tggttttccc ttgccttttc agttcttcta
     1981 ccacaatgct ggctaaacta gtttcttccc cataaccata gcaaaagtct cgtaaagaaa
     2041 ttccttcgaa agtctggcag tccaagattt gattttccaa gatatccagc gcttgattcg
     2101 cctcttcttg actgctagcc tttgttgaca gacgtagagt gacttctcct gtcttggcat
     2161 aaggggccaa ggtaggatcg acctgattat caattaaatc agccaaaatc gtaaccagct
     2221 ggctctcgcc aatcccaaag aaacgaagaa ctcgggaata cagcttgctc cctgtcatca
     2281 acttgggtag aagtaggttt aagaccatgg gtttcaattc acttggcgga cctggaagga
     2341 cgacataggt cactccgtct acttctaatt ttcctccaac agccagtcct gtttcgtttg
     2401 gcagtggaat cgctccttct acaatttgag cttgtctttc gttattcggt gttcgggcat
     2461 agtctggtcg cagggcaaaa aagatatcca acttctcctg agcctgagga tcaaagacta
     2521 atgctttccc taaaaattta gctagggttt gtttggttag gtcgtcctca gttggcccca
     2581 aaccgcctgt caaaatcacc agactgctac gttgactggc aatctcaagc aaagacaaga
     2641 gacgaacttc attgtctcct acagccgtct gaaaatatac atctacccca atctcagcta
     2701 gtttttccga caaaaactgg gcattggtgt tgacaatctg tcctgtcaaa atctctgttc
     2761 caacagcaat gatttctgct ttcatgtttc ctcctaccta tctattcgta tttttttgaa
     2821 aaaatcgcag gaattttcct acgattgatt ttttatttgt atcaaaagtt aattatcttc
     2881 atcaccaaca ggtgctctgc caaataaatc ttcaaataaa accgcattgg tttcaagctg
     2941 agtaacttct tcttgtccca aagaacgtcg gagtatattt tgcatttcca acatatgtgc
     3001 tcttgaaaca atctggtaag aaacaccttg aagtatctct ccttcaccct gcaactgctg
     3061 agtttcaatg gttttaaatg aatctttata gcctagcaag ttagggatac tttttgcaga
     3121 caaatcaata ttggtctgca tattgtcact caaagctttt agaatctctt gataatgacc
     3181 aacgctattt aaactgagag ctttttccat gactttttga ataacttcac gttgacgttt
     3241 ttgacgacca taatccccct caggatcttg gtaacgcatt cgtgcataga ctagggcttt
     3301 ttctccccca atatgttgct ccccaacacc gatagaaata gtattaaatt cttcttggtc
     3361 actgatagaa attgggaaac ctaggatatt attgactgta atacctccta ctgcatccac
     3421 tagtttttgc aaccctctca tattgaccat cacatagcga tcaatatgga tattcatcat
     3481 tttttgaatg gtttctatag caagctctgc tccaccatct gcatatgctg agttcagttt
     3541 cgcttcatga gcctgaccat tccctgattc aatgcgcgtc agaatatccc gctctaaact
     3601 catcattgtt gtttttttcg ttttaggatt cactgtcatc aagatcatgc tatcacttct
     3661 accgacccaa gtttcagttc gttcaacatt tccggtgtcc actcccatta acagaatggt
     3721 tagaggttca gtcgcttcaa taaccttggt ttcttcgccg atttttttat aggttttagc
     3781 taaggtttct gtcccttgtt gataaatagt ataagcaaaa acacctactc ctactacagt
     3841 tacagaaagt aaagctagca ccattccaat aattttttta accatatttc tactaaccta
     3901 tcagtttacc catcaagtaa acatcgataa atttcccttc ttctatatat gccccacgct
     3961 cttggctacc ttcaatgaca aagccatgct tttgataaag atggactgct gcttgattac
     4021 gagtttggac agtcagttgg agacgacgca gaatgccact tgcttgtgcc cactctatcg
     4081 cttcttctag caacaaactt cccaagccat tattccaata tctttttcca atcacaatga
     4141 agagatctcc aatatgacgg actctcttac gctgatcagc tgtaatattt acaataccag
     4201 caattttgcc atttaagaat gcaagtaagg ttatctgatt gtccgaacta gcttgcttgt
     4261 tgaggaatat ttccatctcc tcactagtca agagaatacc atctccgtct aggctggtaa
     4321 agtctgtctc caaactcaca cgatttaaaa aggccactaa ttcagctgca tctttgggct
     4381 ctgcttccct aatgagcaat tcatactcca tattgaagct cctctaacaa tttctcagca
     4441 cgcaaaccct ttgcctgaaa atttaaacgg cgtccatctg cttcttttag aatttccaat
     4501 tctaaataag catctggcaa ggcatctcct aagagatttc cccactcaat aacagtcacg
     4561 ccgccaccaa agataaactc atccaagtcg atagaatcag catctccttc aatacgataa
     4621 acatctaggt gataaagtgg aagtcgacct tcatactctc tcacgatagt ataggtggga
     4681 cttttaatca tttgagaaat ctgtaatcct tttgcaagtc ctttagtaaa ggtcgtttta
     4741 cctgcaccca gttctccagt taagattaaa acatcattct ttgctaatag atggcccaaa
     4801 cgctccccta aggcttgcaa ctcttcttca ttttttgtgt acatactctt attataccaa
     4861 aaacttttct tttgtgtcta ttttcctact aaacttatca tcataacatc cataaaaaac
     4921 aggctttctc taaaagaaaa tgagcgtaac aatgaccaat acaagatctc ggaaaatatg
     4981 accataaaag gaaacttcct tcttaaccga atttgggaca agataggctg caaaaaacaa
     5041 gcccagtcca atataaatca gaagtgagac aatggtcatt ggatttctta agaaaagaag
     5101 tgttgctaaa atagtcacca acactgtctt ttttctgtct agcatagcaa gaaaatcgcg
     5161 cacgtatttt ttcaagggta aaaaaatcag caaatctagc ccaaatagga aaaagaagga
     5221 tggcaataaa aagtcaacta attcttgctg cagcgtattt ttgatgaaca agttatctga
     5281 caaaacaaga acagctccta acaaattaat taagagtaac atactgtaaa aaagcttcac
     5341 cgacttctta ctggctagga cactatggac ttcttgctta cgggtataaa gataatttac
     5401 tccagcacag attcctgaaa cgaaaaccat gctcccgatg aaaaaagctg tactttgttt
     5461 aaaggacaag atgcattcct tccataggaa acagctactc aaactgattt gaattaaagc
     5521 taacaaaaat aagattctca ttgatttcat cttctctctc ccttcctacc aatcattata
     5581 ctaggagaaa agagagaact gtttctaatc ttctcaaatg tctctttaag acgctaaaca
     5641 aacactagag actaatactc aatgaaaatc aaagagcaaa ctaggtagct agccacaggt
     5701 tgctcaaaac actgttttga gattgcagat agagctgacg tgatttgaag agattttcga
     5761 agaatataaa tttgaaatca tgaaaatccg tcaaacgggt ggttgttttg tctcgcacct
     5821 cacggagcga gacggactca gagtcacata attataaggc tgatagtatt aatctaacta
     5881 tcagccttac aggttattta acgtttcaga aaaactataa tgtcaagatt aactaaacag
     5941 tatctaattc cttcaaataa ttttctatct tcatcagcat taaaggattg ttataaatct
     6001 tgcatagctc tcttgcttct atataataat ttttgacttg ttctctgtct agaaatttgg
     6061 ctccagcatt tcctacaaga ataagtagag gagccaattg gtagcttgtc tgtctttgtt
     6121 tacagagttc gatagtctca agagcttctt ggatggcttc attatatttt tcctttgata
     6181 ctaggtagtg agcgtaattg taacgaactc tgatgtagcc aaataaaaac tcttgatgct
     6241 caaaattttt tgtctgatat aactccatca aatgagagta gtttacctca tattcttgtt
     6301 cacgacccac taaggaatag aaattagata gagtattcaa cgcctttaaa taaatcaaag
     6361 tatttgagga gacttttaat aatatatttt ccaatgaaga aattgcttca cacttactgt
     6421 catattgaca gaagtcaata atagctttaa tccattcaag gtaagttcgg tcttctagtg
     6481 ttagaaaagt acttcgttca atctctattc tataaatata ttccaaattt tcataatttc
     6541 tatcatctaa taggcgagca gataattgct tgaaattaga gaggttagat ttaatttcaa
     6601 tttgttcatt aaaaaaataa tctaatggca cttcgagtcg ttgtgagagt ttgaacaaaa
     6661 ggtctgcgga gggaatgaaa taccctctct caattttact aatctggctc tattcacaaa
     6721 ttccttctgc aagagtttgt tgggagagtc tcaactcttt tcttttcaat ctgaatttct
     6781 ctgcgagtgt attcattaaa gataataaac cttcctattt gcttaatttc attataaaat
     6841 ttttagttca aaatagcaag ttaaaggaat aaataattct ttgcggtaat aaacaaaaaa
     6901 aagtcaaaaa ttacataaaa atgcttggct aaataaaata tatttgttaa aataaggata
     6961 atgaaaaaga aaagggtttc acgaatgaag aaaaatcgtg gaattcaaaa attagctata
     7021 ttagtattac taggtgtttt tatgtttagt aacacaattc cttaccaaca gtttattcag
     7081 aagaatagac aattggagat tcgagtccaa tcgcaaaaga agtccaatgg tcttgatgtt
     7141 gggaaggctg attgatttta tattacttta aaattcaact atttagagaa aggtattctg
     7201 atgagagctt gtaacaatac cagatagata taagaatgga gatgtttgat aaaatgcttt
     7261 catagctaac caactgttga aaattatgag ttacaaaatc taaagtattt aagattggtt
     7321 tataaaatta ggtctctgcc tgtagaaagg aacgtgcagt tagaaaggag gaaaaaatag
     7381 gatactataa ttcagactga gatttctaat taaaatatat agttgcattt cgctcatttt
     7441 cataatattt cattcagagg agtaataata tgttaaaatt tagaaaagta gttgcatcat
     7501 cccttgccgt tttggcattt agtttggctc ttcctgtttt ggcagtttct caccgtggtg
     7561 gcgagtggac ctatggaggc catcatgatc caaataattg gggagcattt tcgaattatt
     7621 atcatggttc acagtatcac tgggcctatg ttggaagtaa tggacgtaac aatcaaaaaa
     7681 cagtttatgc aggagcacgt agtgcggcct atgcgtttgt taatacaaat tttggggagc
     7741 aagttacatt tgatgcggga tggtaaagaa taattgaaga agattctttt atcaatagtt
     7801 cagtaagctt gttagtttat agagggcagg ggtatttctg ccctctgttt tagaataagg
     7861 aatgcactat gaaaaaatta tttatactca tatccaacct gcttgctagt ttgttctttg
     7921 tttgggtatt taccatttgg actgatacat atgtctccta ttattacccc aacgttgttg
     7981 tacatgattc ttcccctgaa acaacttttc agcatgttgc tacacgcttg gaaaaactag
     8041 cagaagaaac agatagcttt attgcgattc aacaccaaga tcctaactca gaaggtacta
     8101 cagttttttc ttatacgacc tttggggacg gaaagttgcc tgatgggctt caggaaaaaa
     8161 aactagaaga tgctcaaagt agtagtgttg aaacaaacta ttttgtattc gatggacacc
     8221 tagatattca cttgctaagg gaggagctaa gtcaacttgg cttgactaac atgaacctga
     8281 caattccatc taaactatct acgttaatgg ctatctttag taacggattt cagttaatca
     8341 gtctattgat tttcatctta acctttatag cactgacttt aattagtcaa attagccaat
     8401 tacggtcgtc gggcattcgc ctcatttcag gagagaaacg gtggtccatt ttccttagac
     8461 cagttggtga ggatttgaaa gggatagctg ttggtttcag tttagctggc gtgctcgcca
     8521 ttcttatgca aaaaattctg tcgcttccaa cgcaatccct aatgaccata ggagcaggct
     8581 tgctcagtta taatctcatc ttgttgtcga tctccctgtt tttcgctcaa ctcttcgcag
     8641 ttgggataaa aaagatacac ctgatgcaga ttataaaagg gcaagtgcct gtcagaggaa
     8701 tcattagttt gattttaatc ggtcaactat tagcgattat tattgtaacg ctgggaatag
     8761 ggagtagctt aaagtattcc caagcctggc aacagcatcg gattggacaa gaggcttgga
     8821 gtcaggaaag gcaactgatt accctatcaa tcagccgtga aggaacgagt cctggttttg
     8881 atgaacaagc tcaaaggaaa ctcagaactt ggtatcaatt gatggatctg gctgtttcag
     8941 aacaaaaggc tttcttatct agacaccagt taattgaccg tactttgcaa aatggcatgg
     9001 cttcctccaa aaacttgata acctctacag aatggcacga ttacaacccg aatggcaatg
     9061 tccttatcgt cacaccgcaa tacttggagc gtcaaaacat tcctgtagat acaactattg
     9121 agcaaaagat gaatcacctt gatgtagggg agtttgtctt attgctgcct gaacacctcc
     9181 gttcagagga agaacattat aaatctgttt ttgaagacga cttaaccagt cgcatgtcta
     9241 gtcaagatga acgacagcaa atgactgcta cggtaggtta tttagaatca ggtcaggatc
     9301 gttttgtgta taatacgacc cctatttctt accagcagtt tttgaaagat ccaatcatca
     9361 ttgttataac accccaatca actggtccac agtccatttt gttttggata gacgcagtac
     9421 agaactacgt tctctttaat caattgtctg atgcccagga gcttatccag agacaaggca
     9481 ttgaaaattg ggtctcagaa atgcaaacag gttaccacaa ctacatcaca ttattggata
     9541 atattcagag ggaacgttgg gtaatgctag caggagctgg gcttgggatt gcaacttcaa
     9601 tcttgttgtt taacactatg aataggctct actttgaaga atttagacgt gccattttta
     9661 tcaaacgcat tgcaggtctc aggttcttag aaatccatcg cacttatctc tttgctcaac
     9721 tgggtgtgtt tttactggga tttgttgcga gtgtatttct tcaggtagag ataggagttg
     9781 ctttcttagt cttgttactc tttactggtc tatctctttt acagttacat gtccaaatgc
     9841 agaaagaaaa caagatgtcc atgcttgttt tgaagggagg ttaatatgat tgaacttaaa
     9901 caggtgagta aatcttttgg agaacgagag ttattttcga atctttcaat gacatttgag
     9961 gctggaaaag tctatgcctt aattggttca agtggtagcg gaaaaacaac cttgatgaac
    10021 atgattggga aattagaacc ttatgatggg acgatttttt accgaggtaa agacttggcc
    10081 aattataaat cgagtgattt tttccgtcac gaattgggct acctcttcca gaactttggc
    10141 ttaattgaaa accaaagtat tgaagaaaac cttaagctag gtctcattgg tcaaaagttg
    10201 agtcggtcgg aacagcggtt gaggcagaag caggctttag aacaggtcgg cctgacttat
    10261 cttgacctag ataagcgcat ctttgagtta tcgggcggag aatcgcaacg ggttgccttg
    10321 gcaaaagtta tcttaaagaa tccacccttt attctggcag atgagccaac agcttcaata
    10381 gacccagcaa cttctcagtt gattatggag attctgctat ctcttcgaga tgataatagg
    10441 ctaatcatta tcgcaacaca taatccagca atttgggaga tggctgatga agtgttcacg
    10501 atggatcgtc tgaaataaaa atccttgttt ttaattgcac gatgagttac tgaaatatta
    10561 tcatgaatca ataattggag ttaatttaga attgtacttt attaatattg aggtaacttt
    10621 ttcttgataa aggaagaaat agtggagagg aagttagaat gaaaaaattc gacaattata
    10681 ttgttgagaa gccttgcgat tctaattcag ataaactgca aaaaatctta ataattgaaa
    10741 atttggtaga tgatattttg caatttcctc tcagaatcaa taatagtgta ggagagattt
    10801 tcctcctaca accgtttcaa aagaaaacta tctttattcc atgttatttt gaggaagata
    10861 ttgtgaaagt caaagatgat gataaagttg agtggaattt gttagaattt caaaaattta
    10921 gagcattttt ggcttagtaa tctgtgttga aggctcaaaa cctatggtaa aaaagtcgct
    10981 ttgaaaacgt attgcctcca aagatttagt taaataatga tttaacacaa aaagaaatta
    11041 ttgaagttct ggaaagatgt tgtttcagta ttgagaaaag gtgggaaaaa cttgcgattt
    11101 tcacagagaa aggaagaaaa agtatagaaa tatagtcaat tgaaacaaga acaggacaaa
    11161 agaacctttt gtgccatatt tttctccttt cgctttacaa ttggcttgaa cacctttatt
    11221 gtatcgcgtt tggagttttt ttggtataac cttcgacgcg cacccgcata gcgggtgttt
    11281 ttttgtctcg cacctaacgg agcgagacga actaatagtc acttaatcaa aaaacgcacc
    11341 atatcaaaaa ctaaaaagtt tgatatcatg cgtcatgtct taaactaatt gactatactt
    11401 tctattcaaa tgagctttta accaattgat tgagccaatc cactcttaaa accaaagagc
    11461 aatttctcgc ttagctgact cttctgaatc tgaaccatgt acaacatttt ggataacctc
    11521 attttctcca gcagcttttg caaaatcacc tcgaatagtg cctggtaaag cttcttctgg
    11581 acgagttgca cccatcatgg tccgccaagt ttcgattact ttgggaccag aaatgacacc
    11641 cacaagaact ggacctgaag tcatgaattc acgaatcggt gggtaaaaac tctgaccaac
    11701 caagtcctga tagtgctggt caatcaactc ttctgaaact tgtgaacgaa actccaattt
    11761 ttcgattgta aatccacgtt gttcgatgcg ctttaacact tcacccacta gccctctttt
    11821 tacaccatct ggtttgatga taaagaatgt ttgttccata cccgtctcct ttgtcagctt
    11881 ctttctttta ttttaccaca tttcgtggaa aaatggagaa agttttcaga atagagaatg
    11941 agagaacccg agggttctct cattctctat tattctactg tttcttccac agtttcaacg
    12001 gcagtatcca caactacttc tgttgtttct tcatttcctt cttcctctac tggaggatta
    12061 aggtattctt cttcgttgac agcatatggt tcaaggttac ggtaacgggc cataccagta
    12121 ccagctggga tgatcttacc gatgataaca ttttctttaa gtccaaggag atggtctttc
    12181 ttaccacgga tagctgcgtc agtaaggaca cgagttgttt cctggaagga agccgctgac
    12241 aagaaactgt ttgtttcaag tgaggctttg gtaattccca taaggactgg gcgacctgtc
    12301 gctggaactc cacctgcgat aaggacatct ttgttggcat ctgtaaagtc attgatatcc
    12361 atgagggtac ccatgagaag atctgtatca cctggatcca tgacacggac tttacggatc
    12421 atttgacgaa ccattacctc gatgtgtttg tcaccgattt ctaccccttg gctacggtaa
    12481 actttttgta cttcaccgag aaggtacgtt tcaactgaca agacatcacg aactgcaagg
    12541 agacgttttg gttggataga accttctgtc agagcagcac cacgcgctac ttggccccca
    12601 acttcgacac gcatacgagc tgtaaatgga acgacatatt caccttcgcc agtttcaccc
    12661 ttaacaaaga ctttcttggt acgagttgat gcatcttctt cgatagcagt aacttctcct
    12721 ttaacctctg tgataaccgc ttccccttta ggattgcggg cttcaaagat ttcttggaca
    12781 cgaggaagac cctgagtgat atcggtattt gaggcaaccc cacctgtgtg gaaggtacgc
    12841 attgtaagct gtgtaccagg ttccccgata gattgggcag caatggtacc aactgcttca
    12901 ccaacttcaa ccgcatcacc agtcgccaag ttgataccgt aacagtgacg gcagacaccg
    12961 tgacgagtgt tacatgtaaa tacagaacgg atagtcactt cttccacacc agcattgaca
    13021 atttcacgcg ccttgtcttc tgtaatcaat tcatttggac caataatcac tgcaccagtt
    13081 tctggatgtt taacagtttt cttagtgtaa cgaccgttga gacgctcttc gagagactcg
    13141 atcatctctt ttccttctgc gatagaacgg atcaagagac cacggtcagt tccacagtcg
    13201 tcctcacgga tgataacgtc ttgggcaacg tcgaccaaac gacgagtcaa gtaacctgag
    13261 tcggctgtct taagggccgt atcggtcata cctttacgag caccgtgagt tgagaagaac
    13321 atttccaata ccgacaaacc ttcgcggaag tttgaaagga ttggcaattc catgatacgt
    13381 ccattcggag cagccatcag accacgcata ccggcaagct gtgagaagtt tgagatgtta
    13441 ccacgggctc cagagtccat catcataacg attgggttct taggatcttg gttagcaatc
    13501 aagcgtttct caagtttttc acgggcagca cgccattcag ctgtaacagc attgtaacgc
    13561 tcgtcgtctg tgatcatacc acgacggaat tgtttggtga tttgctcgac acgtttgtgt
    13621 gattcttcaa tgatttcagc cttgtcatca acgactggga tatcggcaat acccactgtc
    13681 aatcctgcaa gagttgagtg gtggtaaccg agattcttca tgcggtcaag tagggcagaa
    13741 gtttctgtcg tacggaaacg tttgaagatt tcagcgatga tatttccgag gtttttcttc
    13801 ttgaacggag ggttgagctc aagattgctg atagcttcct tgatatctcc accaagtggc
    13861 aagaagtatt tagctggaac accttctgtc aagttggcat tgtttggttc ttgcaagtat
    13921 ggtagcccct ctggcatgat atcgttgaag agaattttac caactgttgt aagcaagacc
    13981 ttatgtcttt gctcttctgt ccaaggcttg ttgaggctgt ctgttgcgat accaacacgt
    14041 gagtggaggt gaacataacc attgcggtaa gccataaccg cttcgtcacg gtctttgaag
    14101 accattcctt caccttcgcg accagcttct tccatggtca agtagtagtt acccaaaacc
    14161 atgtcctgag atggagtaac taccggtttc ccatctttcg gattcaagat gtgctcagca
    14221 gctagcatga ggatacgagc ttctgcttgt gcttcttctg aaagtggtac gtggatggcc
    14281 atttggtccc cgtcaaagtc agcattgtag gcttcacaga caagtgggtg caagcgaaga
    14341 gccttaccat caatcaagac tggctcgaag gcttggatac ccaaacggtg aagggtcggt
    14401 gcgcggttca aaagcactgg gtgttcttta atcacttctt caaggatatc ccagatacgc
    14461 tcatctccgc gttccaccaa gcgtttagct gctttgacgt tttgcacgat atcacgggca
    14521 acgatttcac gcatgacaaa tggtttaaag agttcaatcg ccatttcacg tggcacacca
    14581 cattggtaca tcttaagagt tggaccaacg gcgataacgg aacgtcctga gaagtcaaca
    14641 cgtttaccga gcaagttttg acggaagcgt ccttgtttac ctttaagcat gtggctcaat
    14701 gatttcaatg gacggctacc tggtcctgtg attggacgac cacgacgacc attgtcaatc
    14761 aaagcgtcaa ctgcttcttg aagcatacgc ttctcatttt gaacgatgat acctggtgca
    14821 tttaactcaa gcaaacgagc caaacggttg ttacggttga taacacggcg gtaaaggtca
    14881 ttcaagtcag atgaggcaaa acggccacca tccaactgca acattggacg aagatctggt
    14941 gggataaccg gaagaatgtt aagaatcatc cattcaggtt tgtttccaga cttgtaaaag
    15001 gcatccaaaa catccaaacg acggatggct ttgacacgtt tttgtccagt agctgttttc
    15061 aattcttctt tgagttcagc aatttctttt tcaagatcta cttgcttcaa aaggtcttgg
    15121 atggcttccg cacccatctt ggcaacaaat gaaccataac catattcacg caagcgctct
    15181 cggtattcgc gctctgtcat gatagacttg tgctcaagtg gtgtatcctt aggatcaatc
    15241 accacataag ccgcaaagta gataacttcc tcgagggcac gagggctcat atcaagggtc
    15301 aagcccatac ggcttggaat ccccttgaag taccagatgt gagatacagg agctttcaat
    15361 tcgatatgtc ccatacgctc acgacgaact ttcgtacgcg ttacttcaac cccacagcgg
    15421 tcacaaacaa ttcctctgta acgaatgcgt ttgtacttac cacaagcaca ttcccagtct
    15481 tttgtaggac caaagatcac ttcatcaaag agtccttcac gttctggttt caaggtacga
    15541 taattgattg tttcaggttt tttgacttct ccataagacc atgaacggac tttacttgga
    15601 gaagctaggg tgatttgcat acttttaaaa cgatttacat caaccactat ttcttccctt
    15661 tctattctaa gtgaactgct tattcttgtt cagcagcttc ttctgttgct tccgcttttg
    15721 ttgctttctc agcttcttca gcttcaaagg ctgctttagc ctcttgagct gctttttcgc
    15781 gggctttttc aaggtcatct acgtggatga catcttcgtc cattccttca tccaagtcgc
    15841 gaagttccac ttcttggtca tcttcgtcta ggacacgcat gtcaagacca agagattgca
    15901 attctttgac aagaactcgg aaggattctg gaacacctgg ttttggaatt ggtttgcctt
    15961 ttgtaatagc ttcataggct ttcaaacgtc cgttgatatc gtccgacttg taagtcaaga
    16021 tttcttgaag gacatttgac gcaccgtagg cttcaagagc ccaaacctcc atctcaccga
    16081 aacgttgtcc accaaactga gctttacctc cgagtggttg ttgggtaaca gttgagtaag
    16141 gtccgactga acgcgcatgc aatttatcgt caaccatgtg gtggagtttg atcatgtaca
    16201 tgactccaac agaaacacgg ttatcaaatg gttcacctgt acgtccatcg taaaggattg
    16261 tcttggcatc gctatccata cctgcttctt taacagttga ccaaagatct tcagaacttg
    16321 ctccatcaaa gactggtgtc gcaatgtgaa taccaagagt acgagctgcc ataccaaggt
    16381 gaagctccat aacctgaccg atattcatac gtgatggcac cccaagtggg ttcaacatga
    16441 tgtcgactgg agttccgtct ggaaggtaag gcatgtcttc tacaggaacg atacgagaga
    16501 caaccccttt gtttccgtga cgtccggcca ttttatctcc gaccttaatc ttacgttttt
    16561 gagcgatgta aacacgaacc aacatgttaa cacctgattg caactcatct ccatttacac
    16621 gtgtaaagat cttaacatca cgaacgacac catcggcacc gtgtggtaca cgaagagaag
    16681 tatcacgcac ttcacgagac ttgtctccaa agatagcgtg caagagacgt tcttcagctg
    16741 aaagatcttt ctcaccctta ggtgttactt tacctacaag aatatcacct tctttaacct
    16801 cagcaccaat acggataatc cccatttcgt caaggtcttt gagggcatct tcaccaacgt
    16861 ttggaatttc gcgagtgatt tcttcaggcc caagctttgt atcgcgcgtt tctgattcgt
    16921 attcttcaag gtgaacagat gtgtagacat cgtccttcac caagcgttcg ctcatgataa
    16981 cggcatcctc gaagttgtaa ccttcccaag tcatgtaggc aacgattggg ttttgtccaa
    17041 gcgccatttc tccattttcc atagaaggtc cgtcagcgat gaaatcgcct ttttcaacga
    17101 catcaccaac ttttacgaga gtgcgttggt tgtaagcagt acctgagttt gaacgacgga
    17161 atttttggat gtggtaaaca tccaatgaac catcttcacg acgaacttct accttgtcag
    17221 catctgcgta agtaacttta ccatcatact gagcaatcac agccgcacca gaatcgtggg
    17281 ctgcttggta ttccatacca gtaccaacgt aaggtgcctg aggattaatc aatggcacag
    17341 cctgacgttg catattggct cccatgaggg cacggttgga gtcatcgttt tccaagaaag
    17401 gaatacatgc tgtcgcaacg gcaactacct gttttggtga aacgtccatg tagtcaacaa
    17461 tattagctgg atactcttgg ttgacccctt ggtgacgtcc catgacaatc ttctcagcaa
    17521 aggttccatc ttcattcaga ctagagttag cctgagctac agtatattca tcttcttcat
    17581 cagctgtcaa ccaaacaatt tcgttcgtga caacacctgt ttcacggtca accttacggt
    17641 atggtgtttg aacaaaacca tatttgttca agtgtccgta agatgacaag ttattgatca
    17701 aaccgatgtt aggtccttca ggtgtctcga ttggacacat acgaccatag tgagtgtagt
    17761 gcacgtcacg tacttcatat ccagcacggt cacgagtcaa accaccaggt cctaaggctg
    17821 acaaacggcg tttgtgagac aactcagaaa gcgggttgtg ttggtccatg aactgtgaca
    17881 actgtgatga accaaagaat tctttaactg cagctgttac aggacggata ttgataattt
    17941 gttgtggtgt caagacttca ttgtcctgaa cagacatacg ttcacggaca ttacgttcca
    18001 tacgagaaag tcccaaacgt acttggttgg caagcaattc accaaccgca cggatacgac
    18061 gatttccaag gtggtcgata tcatctacac ggccaagtcc ttcagccaag ttgaggaagt
    18121 agctcatctc agcaaggata tctgcaggag tcaccgtacg aaccttgtca tctgggttag
    18181 cattaccaat gatcgttacg acgcgatctg gatcagttgg agcaacaacc ttgaattttt
    18241 gaagaacaac aggctcagtc acaacggctg catcgtttgg gatgtagaca atcttgttca
    18301 agtcgccatc caaatggctt tcaatgcttt caatcacgct acgagtcata atcgtaccag
    18361 cttctaccaa gatttctcca gtttcagggt ctaccaatgg ctctgcaatg gtttggttga
    18421 gcaaacgtgt tttaacattg agttttttat tgattttgta acgaccaact gctgccaagt
    18481 catagcgacg tgggtcaaag aagcgagcca caagcaagct acgtgagctt tcagctgtct
    18541 taggctcacc tggacgaagg cgttcgtaaa tttctttcaa ggcttcgtct gtacgagagt
    18601 ccattggatt cttgtggata tctttttcaa cagtgttgcg aaccaattcg ctgtcaccaa
    18661 agatatcaaa gatttcatca tcacctgaga aaccaagagc acgaaccaag gttgtaaatg
    18721 gaatcttacg agtacggtcg atacgagtgt aggtgatatc ttttgagtcg ctttcaagtt
    18781 ccaaccaagc tccacggtta gggataacag ttgaaccata gcccacctta ccatttttgt
    18841 ctactttgtc gttaaagtaa acacctggtg agcggaccaa ctgagaaacg ataatacgtt
    18901 caccaccatt gatgatgaaa gtacccattt ctgtcatgat tgggaaatca ccaaagaaaa
    18961 cttcttgggt cttgatttcg cctgtttctt tattgatcaa gcggaaggtt acaaaaattg
    19021 gtgctgagta gctagcatcg tggatacgag cttcttctag cgtgtatttt ggttccttga
    19081 tttcatatcc aacaaattcc aactccattg tgtctgtgaa gtttgaaatt ggcaatacat
    19141 cttcaaacac ttccttaaga ccgtggtcta ggaaagcttt gaatgagtca gtttgaattt
    19201 caatcaaatt tggtaagtca agaacttctt tgattcttga aaaactacga cgggtacgat
    19261 gtttcccgta ttgaacgtca tgtcctgcca agatgattct cctttgtaaa taagttccaa
    19321 gccttgtcaa tcaggctttt ctaatcgcca tatggttgta aaccccttat caccgtgtcc
    19381 tcttgacgaa ttttcagaat ctttaagcct ctgttacaaa tgctcaaaat cttgaaaaaa
    19441 agcacaaaaa gagcagctaa atctgacttt ttcagaagat ttaactgctg tgagccttgt
    19501 ctggacaata tttcagacaa aacctacgac aaatgattac ccatattata ccctatttag
    19561 ctagattttt caaggggatt cagtaggttt ttggtaattt ttttcccata gaaaacttgg
    19621 catcacattc gaatcacgct atggtacaaa aaactgaaaa aactattgac tgaaaatcat
    19681 tttcaaggta taataataaa cgttaaggcg gtatagccaa gtggtaaggc acggctctgc
    19741 aaaagcttga tcgtcggttc aaatccgtct accgccttct ataacttgat ttatcaggtt
    19801 tcaaatgaac agaaagccca atttgaaggg ctttttttat tttccctcga ataaatacgt
    19861 ataactttaa aaacttttgg agcgagtttg tggcagagtt ctttccatgg cataattccc
    19921 ttttgaaatc aattgaaaaa agcttcgtca cgcctggtga caaaagcctc tagtttattc
    19981 tgtttcttct tctatttcga cttctgtgat ttggactttt accttggtaa cacgtccatt
    20041 cttcacttta tcattggtta agataaactg tttgttttgg ctgaccaatt catagctgag
    20101 tttctcagtc gttggaatgg ttcccactcc tgtcaaataa taaccagcga tagtatcaac
    20161 gtcatcactt tccagttcaa cattaaagta attattgaaa tcattgaggg tcatagttcc
    20221 ttgaacaatg taggtatcct cgccaatctg atgaacatct attgctgctt tgtccgtttc
    20281 atcatcaatt tcaccaacaa tttcctctaa gaggtcttcc aaagtcacca aaccagccat
    20341 accaccgtat tcatccagca agattgccat ttgtctttgg gtatttcgca gttcttttag
    20401 caagtcatcc acaaaaatag tttcaggtac aaaaagtgga tcttgtaaaa ttctcttcca
    20461 aacaatattg tcaaaaccgt ccacaaagcc tgccttaagg agactcttgg tgtgaatgat
    20521 tccaattaca ttgtccttat ccccatcata aaccgggata cgagaataat tttgttttaa
    20581 aatactttgg ataatggctt gactatcatc ctgaatatcc accataaagg catccgttcg
    20641 aggaaccata acctctcgtg ccatcagttc atcgagcgaa aagacacctt gtaacatctc
    20701 aatctcatca gcatccaatg tttcttcact atttgtcagc atataggcaa tttcatcacg
    20761 ggtcatcttt tcatccgcat catcgaatga cataggagtc aaatggctca agaaattggt
    20821 cgaagcagct aaaagccaaa caaaaggact gactagtttt ccgatcccaa tgataaccgg
    20881 cgctgtacga attgccaagg catcctttag attaagagcg attctcttag gatataattc
    20941 cccaaaaacg atggaaatat aggtcaaaaa tgccaaggat agaaaagttg ccacggcttg
    21001 tgctgtttcg ccattcccaa gccaagaggc aatcacacgt cctagagtat cagttaaact
    21061 cgcccctgat aagattgtaa tcagggtgat tcctacctga atggttgata aaaagtggtt
    21121 aggattttct agtaccttca gcaggcggat gtagcgtctg tctccttctt ccgccttttg
    21181 ttcaactcgg gcacgattaa gagaaaccat ggccatttct gtggctgaga aaaaggcatt
    21241 taataccgtc aagataaaca ataaaacaaa ttgtagcaac aaattctgac tacttgggtc
    21301 ttccatagtt cttctcctaa aatagtatct tatcctttat tatatcacaa aatttaatcc
    21361 aatacatatt atttttttct tagcgtaact tccatctctc tcccaaaact ggaagttagt
    21421 ctaagacgga tttccactga tttcacgcgt ttttctcata ctaaaagcta ggttgtggga
    21481 aactggaagt tagttttaga agttactatt ttttcttagt acctgttcta gccctgctta
    21541 aactagtaaa aagaactcct acatccataa gtgacatagg agtttaggct tatcttttac
    21601 tgagttacag ttacttctcc agttcggtaa tccagttgaa gtcccttttg aacattggga
    21661 actagaacat tgaattccaa ttctccatcc gaagacttgg cttcaatctg tgaagctgag
    21721 ggaactaaat cctcgtttga agcgtagtaa agggttacac ggtaacggac acgcttgttt
    21781 tggtccaagg ctttacgcac cttgctttca tagtagtttt gaccagtcga atactcggct
    21841 tgtgcctgat ttgcccaggc tgtctgaaca gcaatgtttt taggattgct tgttgaggca
    21901 tcaaaaccat ccaaaccacc gattaaggca tagcctaaca aatgacctct atcgactgca
    21961 tgggtataag agccctttag attcttgacc tgatgccaac ctggaggagt ccaagaagtt
    22021 gaaccattcc cagtttcttt acgattcttg tactgacgag tggccttaga caagagggca
    22081 ttagctacgg ttggaacagt ttccttaccc actgtctttg ttttattgtc agcgtagggc
    22141 ttacttgaaa ccttggcatc tagatttgtt ttattaccat tgacgataaa agcacctgag
    22201 ccattccact ccagactccc ctttatttga ctcttgactg cgtctgttaa gacactctct
    22261 gccaatgctt gactaggagc ttcaggcgct tgttttttct gactaagctt ggttttagga
    22321 ctattagctg tcgactgcat ctgcttgata taatagctcc ctgtagacaa aagcaataac
    22381 actagcagtc cgattagtgt ctgtcttgtt tttttgttca tatttctcct tatctttaga
    22441 aaaaggctgg ttctccagcc taatttcctg taaatttatg aatcaattcc tgccattttg
    22501 ctggagacag gatagcccat gaatcttgac ccttgcccaa gattccataa cctaccatta
    22561 aaccgattcc tagagccaga gtacctaaaa tcagtactat gatgactaaa agtaaacgct
    22621 tgactacgta gcttgatttc ttattcatct tcatcacttg cctcaatccg ctgaatctta
    22681 gcacctagct gcgccaactt ctcatggaaa ccgtagtaac ctctatccaa gtgaaccaat
    22741 ttaccgacca cagtttctcc ctgtgctacc aaacctgtca aaatcaaagc tgcactggca
    22801 cgaaggtcag ttgaaagaac ttctgctccc tgcaaaggct gtccaccaac aatacgagct
    22861 gtatcacgga taatctcaga atgcaagccc atgcggcgca tctcttctag gtgttggaaa
    22921 cgattttcaa aaactgtctc caccatggtt gattcgcctt ttgcaactgt catcaaggct
    22981 gtaaattgag cctgcatatc tgttggaaat cctgggtggg gcaaggtttt cacatgaaca
    23041 gcttttagat tttccagttg agaacgaaca cgaattcctt cgtcttcttc aattacttca
    23101 acacccattt caagtaactt ggcaatcaag ggacggttgt gctcccagac agcgtctcga
    23161 atcaagacat caccaccagt catggcagca gctaccataa aggttcctgc ttcgatacgg
    23221 tcctggacta cattgtgagt cgtaccatga agtttctcaa caccagtaat ggttatagtc
    23281 tctgtaccag cacctttgac cttggctccc atttcattaa ggagaatggc taagtcaaca
    23341 atctcaggct cacgcgcagc attctcaatc actgtcaccc catcagccag agtcgctgcc
    23401 atcatcaagt tctgcgttgc accaacactt ggaaagtcca tatagatatg agcaccatgc
    23461 aagcgttctg cctttgcttc gatgtaacca gctgtctgac taatcttaac ccccatagct
    23521 tccagacctt tcaaatgaag atcaatagga cggctaccaa tcgtacaacc acctggcatg
    23581 gataccttgg catgacccac acgggcaagg attggcccta atacaacgat ggaggcgcgc
    23641 atcttactga catacttgta aggggcttcc tcagtgatgt cgccagtagc atccaccttg
    23701 acaagatgag cttcctcatc aaagtcaacc ttggcattca aaccaccaac tacctgattc
    23761 ataataaaga catccgacaa aatcggaaca ttctgcaaga cggtctttcc ttcacttgct
    23821 agaatagtcg ctgccaacaa gggtaagact gcattttttg ctccctcgat cgtcacgctt
    23881 cctaccagac gattatcgcc accttgaacc acaattttat ccatactcgt ttcctttact
    23941 cttgatttta taataatcct ctaagcgctt cttgccacaa atgatacagg ctaataaaga
    24001 aagaactcag gatgtagcct atgacaatgc taaaaaaggc tactaataca cgaacttttc
    24061 ttgtattctc agctgtcact tttaaaacct tttcccatct aacaagatcc tttaaaaggt
    24121 aaaaactcac ataaataaag agcatatgac tacttagagt gaataataat tgaaccattt
    24181 gactattata ccatcttctc tgtttgtgcg ctagtttgga aacttcactc aaaaattagg
    24241 gattgttttt caagtaatca atcgcatctt gtagggtttt aacgggcacg attttcatat
    24301 ccgtcttgat tgttttagcc gcttctaggg ctgtttggta gttgtttttc gcgtccggat
    24361 gcgccttttg ttcttcttcg ctaacagggt tatcaggagc aaagaaaata gcagcacctg
    24421 ccctagccga agctacaacc ttcttatcaa tacctccaat gtctcccaca ttaccatcgc
    24481 ggtcaatggt acctgtaccg gcaacaatac gaccattacg aagatctggg tgagctattt
    24541 gagtatagat agctagacta aacatgagac cagcacttgg gccgccaata ccagctgttg
    24601 aaaagctaat tgggacattg ctgattacct ctgtacgatc aatcaagccg attccaatcc
    24661 cattttttcc attttccaag gtgataatct tcccttctgc agacttggtt tgcccatcct
    24721 cttcataggt gaccttgacg gaatccccta atttttgaga actgacgtaa tcaatcaagt
    24781 ctttggaact atcaaaggtc tgatcattga ctgctgtgac tgtatcagag atattgagaa
    24841 tccctttaaa ggttgaatta tccgtcacat tcaaaacata aactccaaag tacttgagtt
    24901 cgatatcctt accagctgtt tttagtcctt gatacttggc catattttgc gatgtttgca
    24961 tgtagaattg attgattcgc ataaattcaa catcggaaga accacctgta gtctcctgag
    25021 cactacgaat atctgtaaaa ggtgtcaacc aagcataaat catatgagct aaagtagcat
    25081 gttgaacacc aaccgtaacg aattgatagg caccagcttc cttatcttct gtgtcattta
    25141 ctttaaggac ttggcgaata tcttccgaac cacctggaac ctctatataa taaggcaagg
    25201 gcactacaaa tgccaagaaa gtcacaatca aggccgcaat gacgtataag ggccatctaa
    25261 tctttttttt catttcttat ttcctccaaa atactctcgg gaacatagca ggcaatatcc
    25321 tgaccaaact tcaaaagctc tctaacgcct gatgaactga tatagagatg ttcaggtcga
    25381 ctatgtaaat aaatagtctc tatatcagaa gacagctgat gattgtagta atcaaaactg
    25441 gcttcatatt gcaaatccga cgcattcctc aaaccacgca ctagacaagt agcacccaat
    25501 ctttttgcaa catcgaccac caattcatca tgagaagcca cgacttcaac attttccaaa
    25561 tgtcccaaag ccttttctag cccccgttta cgattttcaa gagggagaaa tccttgtttg
    25621 tggggattaa aaaaaatacc cacacaaagc ttatcaaaaa gtctgctcgc ccgttcaatg
    25681 atatccagat gcccatttgt catcggatca aatgagcctg tgaataagcc aatcttatct
    25741 gacatagact gtcaccttac taattccata aatcttttcc ttccagatac ccagacaggc
    25801 aatttcttct ggaagttcaa cggtcttatc cgtctcgcac acaaccataa catcttcaga
    25861 aaaaagctct ctctcagcca ttttttcaat atctgctacg atttgttcct tggcataggg
    25921 agggtctaag aaaacgaggt caaattcccc agatacctgt tccaatgccc tttctgcatc
    25981 cattttgagg agttgaaatt ttccaacttc cttggtcatc tggatatttt cagccacgat
    26041 ggtctgagcc ttacggtctc gctccaccaa aacagcactg gacatgccac gcgatactgc
    26101 ttcgatagat aaaccaccac tacctgcata aaggtccaag actcgtccca cttcaaagta
    26161 gggaccaatc atgttaaaaa tggctcccct aaccttatcc gaagtaggtc ttgttgtctt
    26221 gccttctagt gtcttgaggg gacgtccccc atagattcct gatacgattt tcatactgtt
    26281 tattatacca aattatagac aaaaagagaa agaaaaccga accttgcggt tcgattctct
    26341 acaaaatatt ttcgtaagta tcgcggactt cttgaggcca aacacttgtt tgcacttctc
    26401 cgatgtgtct cttgcgaagt aggaacatgg ccatacgaga ttgtccaatt cctccaccga
    26461 ttgtcaatgg gaataggcca ttcaacaaag acttgtgcca ttccaattct aagcggtctt
    26521 catcacctgt aatttccacc tgacgtctaa gagtttcttc atctacacga attcccatag
    26581 aagacaactc aaaggctcca cctaaagact cattccagac aagaatatca ccatttagac
    26641 ccttgtagcc attctcagac tcgcttgtcc agtcatcata gtctggtgca cgtccatcgt
    26701 gcggtttacc atctggcaac tcgccaccga taccaatcaa aaagacggct ccaaattctt
    26761 tacaaatcgc attttcacgt tctttaggtg tcaagtctgg gtagcgttct accaattctt
    26821 ctgtatggat aaaggtgatt tgttttggca agatagactc gatgtcatag cgggcttcaa
    26881 cagctagctc agtcaggcga atagccttat aaatcttctc aactgtttct tttagataaa
    26941 cgatgttacg cttaccattt gggataacct tctcccagtc ccactggtca acataaacag
    27001 agtgggttgc atccaaggaa tcctcatctg gacgaagggc tttcatgtgg acaaagagac
    27061 cctctccttc accaaagcca aaacgagcca aggtgtggcg tttccattta gcaagtgagt
    27121 gcaccacttc ataagtagca tcagggattt ggagaacctt gaccgatact ggattttcca
    27181 caccagacag gttgtcctgc attccgtcac cgaccttact caagatagga ccttgaactt
    27241 cgacaacttc tagcttatct ttcaaatact gggtaaaagt gtttttgaca aaggaaattt
    27301 cttcttgttg atggataaaa cttttcttca tagacaactc ctcaaaaatt taataaacgt
    27361 attatacacc tatttccaag aaaagaaaag agaaaatttt aaaaaaatca gtgtcactca
    27421 aaacactgat ttcatagacc ttttagtcat tgcgaccaaa gatacgtaga atacttagga
    27481 aaagattgat aaaatcaaga tagatgctga gagccattga caccacccag cctgtcgcta
    27541 cacgaccttg tgattgttca taggcgaggc gaatcttttg gttatcccaa gcaatcaacc
    27601 ctgaaaaaac caaaaccatg gctacgctaa tcatataatc aaagaagcca ctagccaaga
    27661 aaatattgac taccatagca atcagtaaac caatgagagc tgccatcatt gctcgaccaa
    27721 tcccactcaa gtctttcttg gtaaaaatac caactgccgc catgacaaag aagagaaggg
    27781 cgctcgatac aaaggcagat aaaactgtac ccggagtata gaaagccacc acaaaactaa
    27841 gggtaaagcc gtttaaaacg gagtaaagta aaaatactgg aagagcagct ggactatttc
    27901 ttgaagccat gctactggca acgaaaacca aagccaactc cgcaaaagta gcaatggtca
    27961 accagagacg cccctgcatc aacaagtaaa ccaactgaga ctgaaagacc gtcaacataa
    28021 ggcctgatac caaagcagat agtccgattc ccagaccaac aaaggcataa accttagcgt
    28081 aaaattgatt gagacctgca cggtcatgta taatagtgtg attcatcctt ttctcctttt
    28141 ctgtgaacat ctttccttga ttataacaaa aaaagttaaa attagcttaa atggaagatt
    28201 aaaataccgg ctgcaactgc aacattcaaa ctctcggcct gccccttcat gctaatatgg
    28261 accaactggt ctgcactttc agccataagg ggactaattc cttgaccctc atttcccata
    28321 actagtacaa aattttctat agaaggcagt tctctgtaat caacagaatc tttagatagg
    28381 gttgttgcta gcactgggat agctaccttt ttagtttcgt caagaagcgc ttgactagtc
    28441 atccggtaaa tgggcagatg gaaatgacta ccttgcatgg aacgtagggt tttgagactg
    28501 tagatgtctg ccgacttatc tgaaacaatc actcctgtaa aacctgctgc atccgcagtt
    28561 cgaatgatag ttcctacatt accaggatct tgcacatctt ccaaaaacaa gaacttgccc
    28621 tgactcaaat cagcttgtcc tacttcttct ttttgaacca cggcaacaat tccctgtgga
    28681 gtctgagaat ccgccaaatc tagcaaaata tcctctgaaa tccagacagt ttgcggaaaa
    28741 gcagctaact gatttcgata attttctagg gcaaagattt tctcaatcgt cactccagct
    28801 tggacagctt cttcaaacaa gtgccagcct tcaatcaaat aggcagactt gcggtatttt
    28861 ttttggtgta atttcttggc attttttacc acagaattgg cttttgaggt tataatagtc
    28921 atagaaatat tataacacaa tcaaaggggt ttggtatgca aaaggttaga atgattgccc
    28981 aaggtagggt gcagggagtc ggctttcgtt ggggtgttta tagcctggcc cttgaaatcg
    29041 gtggcatcac aggtcgggta tggaataacg acgatggcac agtggaaatc ttagcccaag
    29101 cagactcatc tgctatcatg gcaaaattta tccaagaaat ccgaaaagga ccgacacctt
    29161 tttcaaaagt aagctactta gatgtcaaac taagcaactt tcctccctac tctgacttta
    29221 aaatcgcaaa ttaggtctcc agaactattg tatattttgt aaaaaaacag tagaatagaa
    29281 aggtataatt tttaaagaag gaataaaaac agtgaaatct attaaacgtt ttgcattctc
    29341 ggctatggga gtggctatgt tgcttgtctt gactggctgt gtcaatgtcg ataaaaccac
    29401 aggtcagcca acaggattta tttggaatac gatcggagcg cctatggctg aagccatcaa
    29461 gtacttcgct actgataaag gtctaggctt tggtgtcgct atcattatcg taaccattat
    29521 cgtacgcttg attatcttac cacttggtat ctaccaatca tggaaggcaa cgcttcactc
    29581 tgaaaagatg aacgctctca agcatgtcct tgagccacac caaacacgtc tcaaagaagc
    29641 aactactcaa gaagaaaaac tcgaagccca acaagccctc tttgccgctc aaaaagagca
    29701 cggcatcagc atgtttggtg gtgtaggatg tttccctatc ctccttcaaa tgcctttctt
    29761 ctctgctatc tactttgctg cccaacatac tgaaggggtt gctcaagcaa gctacctagg
    29821 cattcctcta ggttctccaa gtatgatttt ggttgcctgt gctggtgtcc tttactatct
    29881 tcaatcgctc ctttcacttc acggagtaga agatgaaatg caaagagaac aaatcaagaa
    29941 aatgatttac atgagcccac tcatgatcgt cgtcttctcc ctcttctcac cagctagtgt
    30001 cacactttac tgggttgtcg gtggtttcat gatgattctc caacagttta tcgtcaacta
    30061 tatcgttcgt ccaaaacttc gcaaaaaagt ccgtgaagaa ctagccaaga acccaccaaa
    30121 agcaagtgct ttctctaaac caagtggacg aaaagacgtt acccctgaac aaccaactgc
    30181 tatcacaagc aagaaaaaac acaaaaatcg caacgctgga aaacaacgtt cgagataaga
    30241 agaaaaaggc ttagctgatt tgctaagtct ttttgcaaat caaaagcccg atgtttccat
    30301 caggcttctt ttctatccat gtacacgttt catataatct tgataacttt cggtatccat
    30361 gagtttttta gcgttcttga cgcgatctgc tgttggtggt ttgactcctt cgagggaata
    30421 tggaattcca agttcacgcc acttgaactc acccatggtg tgataaggta gaatttcaaa
    30481 cttatcaaca tttttgaggg tcttgacgaa cttaccaagt tcaatcaagt catcatctct
    30541 gtctgtcaat cctggaacta gcacgtggcg aatccagaca ggttttccaa tatctgatag
    30601 atactgggca caagccaaga tatttttatt agtttggcta gtgacaatct tgtgctgttc
    30661 ttcgttgatt tccttgatat ccaaaagaac caagtcagtg acagccatga gtttgtcaaa
    30721 cttctcaagg taacgtggtt tattacggaa aggaagagca caggtatcca aggtacagtg
    30781 gattccttgt tccttagcct tggtgaagag agcaatcagg aaatcaatct gcaagagagc
    30841 ttctcctcca ctgactgtaa tcccaccctt atttccccag aaaccacggt agcgcaaggc
    30901 ctctgtcaag acatcatcta ccgtccgttc acgtgactta ttggactcca tagcccaagt
    30961 gtctgggttg tggcaatact ggcaacgcat gtgacagccc tgcaaaaaga caataaagcg
    31021 aataccaggc ccatctactg acccaaagct ttctgtcgaa tgcaccattc ctgtcacttg
    31081 tccataatca attgtttctt cagacatatc gttaccttcc ttgaaaacgt tttatagttt
    31141 tattatatca cgacttgaag gaaaaacaag atttttgcct attttttaga aagcaatctg
    31201 tttttcaatt tcattttcaa tctattatca gattattctt caaaatcgaa gccatataag
    31261 gttgcaaaat agtcctcagg gcgctctgca cggcggattt gacgggcttt accttcttcg
    31321 gtatagagga tttccgcaga acgtaatttg gcattatact ggtagcccat tgaaaatccg
    31381 tgggcacctg tatcatgaat taccagcaaa tcaccgattt ctgtatgagg cagttcgcga
    31441 ttgactgcaa atttatcatt gttttcacag agtgaaccaa ccacatctac cgcttcagct
    31501 ggtccatctg gatgggtcac gttgctaata tgatggtaag ctccgtacat agctggacgc
    31561 atgaggttga ctgctgaggc atccacacct agataggtac ggtaggtttc cttcttatga
    31621 gtcactcttg tgactagagc accgtgaggt gccagcataa aacgacccaa ttcggtgaaa
    31681 atcttgacct gaccaagacc tgctgacgta agaacttctt catacacctt acgaactccc
    31741 tcaccaatca aggcgatatc gttcggctcc tggtctggac gataattaac accaataccg
    31801 ccagaaagat tgataaagtc tagcgaaatg cccaactttt ccttgatttc aacagccagt
    31861 tcaaagagct gacgagccaa ctctggataa tagagatggg tcacggtatt ggacgctagg
    31921 aaggagtgaa tcccaaaagt cttggctcct ttttccttca agatagcaaa ggcttcaaag
    31981 agctggtcct tggtcatgcc aaacttagcc tccccaggat tgtccataat gtctgtcccc
    32041 agttcaaaaa cgcctccagg attataacga caagagatga tttctggaat gcctgctact
    32101 ctctccagat gttcaatatc ttcaaaggca tccaagttaa tggtcgcacc caattcacgt
    32161 gcataggcgt attccttgtc tggcgtgttg ttggaagaga acataatctc agaacccaga
    32221 aagtccagtt tatggctcat caaaagctct acataactag agcagtccac accacaacct
    32281 tcttcttgga gaattttcaa aatagctgga gttggagtag ccttaactgc aaaatattcc
    32341 ttaaagccct tgttccacga aaaagcttgg ttgacggctc ttgccttctc acgaatcccc
    32401 ttctcatcat acaagtgaaa gggagtcggg aactcggcaa caatcgcttc taactcttct
    32461 ctattgataa atggtgtttt cataagcttc cttctattct gtttgcaaag aaaggctggg
    32521 acaatcgttc caacctttag ttctatctct tatttatctt cgtcaaagat attgccaacc
    32581 tcaacatcga tggcttggtt cttgacatca atattggtta ccttcaagag tgacttgtag
    32641 tcaaactgct tttcacgttc ttcttgggca ttgtccgcaa agaccgctac acctgccagt
    32701 tctgagtcga actcgtgcaa gagactaatc ataccattga ccgttccgcc acctttcaag
    32761 aagtcatcca caatcaagac acggctgcct gccttaagac tacgttttga aaggaacatt
    32821 ttctcgatac ggtcaccact tgaacctgaa acatagttga cgctaacagt tgaaccttcg
    32881 gtaattttca ggtcacggcg cacaatgaca aaagagacat tgaggacatt ggcaactgca
    32941 tttgcaagtg gcacaccctt agttgctacg gtcataaccg cgtcaatttt ttggtccata
    33001 aagcttttgg caataatacg accaatattt ttcaagatgg ctggtgtgct aagcaaatca
    33061 gacagataga tataaccacc tggcaagata cggtcacttt ctgacaactt ggtacgcaag
    33121 tcttcaacca tttccttagc atcctgactc gaaatagacg gtgtgaagat gacacctccg
    33181 ccagccccag tcactgtctg gatatgaccg atttcaattt cctcaaaggc gcgtttgata
    33241 atgacgatat cttctgagat ggatgattta gcagactcat acttttcagc aaaagtattg
    33301 agactagtta gtttataagg attattaatc aaatagttgg aaatgacaac catccgatca
    33361 cttcttctta atttcatttc tatttcctat tccattttta ttcaaaaaat caaaaagcaa
    33421 actagaaagc tggtcgctgg tggttcaaaa cactgttttg agattgtcaa tagaactgac
    33481 aaaccctgta atatacctgc atatatacat acgacaaggc gatactaccc tagtttgaag
    33541 agattttcga agagtattca tttttgtctt ttacttatta taccatattc acataaaaaa
    33601 acgaacattc ttatcctaaa aaatgctcat ttttcttaaa ttatcaatct aaatctggtt
    33661 tatagaagga acgattatcc atagcgaaga ttttattggt catctctcct ttatccacca
    33721 aagccagagc tgttgacatc atcatcatgc ttgcatccag attgtcaatc atatggataa
    33781 tctctgcctc cataatacgt ggacggactg gacttccata ttcaagcaag ccgtggtgac
    33841 tgaggatgac atgacgaagc aaaacgactt cttccttggt atcatcgatg ccgagttcca
    33901 taactgtctt ggtaatttcg ctatcaatga gagcgatatg tccaagaaga ttacctcgca
    33961 ctgtgtactc tgtctggtct ggccccgtca actcgataac cttagctaag tcatgcagca
    34021 taatccccgc atagagcagg ctcttattga gctgaggata aacttcgcta atagcgtctg
    34081 ccaaacgtac catggtcgcc gtatgataag ccaaccccgt ttcaaaggca tggtggttgg
    34141 tcttggcagc tggataggag tagaattcct tatcatactt ggtgtagaga tttcggacaa
    34201 tccgttgcca gacaggattt tcaattttga aaatcatttg cgacatgtag tcacgaattt
    34261 ccttgacatc aactggtgac ttgaccttga aatcggctgg gtcattgggt tcaccagctt
    34321 gaggcaggcg gagagtaatt tgattgactt gaggggtatt gttataaact tctcggcgtc
    34381 ctttcatgtg gacaacctta cctgcggtaa aggcctcaat gttatgaggt tgggcatccc
    34441 agagcttccc atcaatctcg ccactatcat cttggaaggt aaaggctagg tagtttttcc
    34501 cagctcgagt ttgcctcagg tcagctgatt tgattaggta aaagccttca aatagctcat
    34561 cttttttcat gtgactaatc ttcatattct tcctcatttt cttgaaaatg gagtagatca
    34621 agcgcaggct caccttctga caactcaatg tgacggagcg tccgctcgat agctatggta
    34681 cgacggttta ataattcatc aatattgcca gaggcatgtt ggagatgttt ttgtgccttg
    34741 accagaatac caccaaactt gccaaactcg gtcttgacac tggcaagagt cttgctgata
    34801 tggtcggcac tcttttggat attaagggtc ttgaaaccaa ctgatagaga gttaagaagg
    34861 gctgataggg tacttggtcc tgcaacaata atctgttctt cccgtctcaa atcatcaaag
    34921 aagaccggat tgcgcacaat ctctgaataa agaccttctg tcggaacaaa caagattcca
    34981 aagttggttg tccgaggtgg tgctatgtac ttgttcctaa tatccctagc aaagcgcttg
    35041 acgcttgcta ggagtgactt acgacagcgt tcaatctcat ccttgtcacc tgtctcatag
    35101 gcttcttcca agcggtaata atctgccagt ggaaacttag agtcaattgg cagatagacg
    35161 tattcttggt cgccttgtcc gggtaacttg atggcatact ccactcgttc actagagttt
    35221 tcaaccgttg cgtattctcg ttcgtactgg gcaggtgtca tgatgtcttc aataatttgc
    35281 cccagttgca attctcccag aatccctcgc gtcttggttc cagagagaac cttgttaaga
    35341 gctccgacat cacgggcaac tgtctgcatt tctccaaggc cacgattgac agactccagt
    35401 tgtttagaaa ctgtctcaaa ggaagcctgt aagcgtgtct gcaaggtctt ttctagtttt
    35461 tcctcgaccg tctggcgcat ttgttccaaa cgttgctcat ttgattcctg caaggcttgg
    35521 agacgttggt ctgtcttgtc tctagtttgg aggagattat ctgtcatttc ttgacggact
    35581 tgggtcagac cttggtgcaa ttcaatccgc acttcttgca aacggtcgct gacaaccact
    35641 tccaaatctt tttggtctaa ctggctggct tgtctggctt ggtcaaagcg gtaatccaac
    35701 tggtctgaca aatgatctgc ctgatcctcc aagctcttac ttaagtgttt ctcctgccta
    35761 tcctgccttt gccaaatcag aaagagacca gctagattgg caattaataa tagaataagt
    35821 aaactttcca tcctacctcc tgtccttgct atgcagtacg accacataac catctgggca
    35881 agttaccgac acttccctat ctatatattc gttagaagcg tacacttttt taaagaaaaa
    35941 attttcctct gtcaactcat acttggctcc aagaatagtc agctggctat cccgaactgg
    36001 cataaaggct agatagtcgt agtctgaacg aggttctagc tgactgattc cttctggaca
    36061 ataagtaatc aagttttgcc catcctcaat ttctatttga tgcatatagg atgccaactt
    36121 aggattgcta ggcagaaaga cattggccaa catatggtca atacggccac ccaaggcacc
    36181 gaaaatagta acctgagcct gaggattttg cttaaagatg gtcaagagag ccaattccaa
    36241 atcagtatca tctttttctg gccgggcttg gacaaaatac tgggcacgtt tttgaatcac
    36301 ctgtcgctct tcttccgtca cagaatcaaa atctccgact gctagagcaa gaggcaaatc
    36361 ttcttccaag atccagagcg agcctcgatc cacaccaaca aaaccatcaa agtccgtccg
    36421 ataatgaccg cggtctccgc ctgcaaaaac ggcaacccta gtccagttgt tttctgagag
    36481 tttgtactcg ctcattgaca tctcccttaa agacatagga acctgctaca aaaacggtcg
    36541 caccagcttc tttggcttga gcaatagttt ggtcatcaat cccaccatcc acttcaatct
    36601 caaagttcaa acctttttca tcacgaaggg caaccagctc acgaacctta tccatggttt
    36661 ctggcagaaa ggcttgacca ccaaatccag ggttaactgt catgactagg acttggtcaa
    36721 ctagatgaag cacatgctta atcgcttcaa ctggtgtacc aggattgata acaactgatg
    36781 gcttgacacc gagtgaacga atcttttgga gggcaccatg aatatgaggc gttgcttcca
    36841 catggatact aataatatcc gcacctgcac gcacaaagtc ctctaaatga tgctcagggt
    36901 ttgacaccat caagtggcag tcgaaaacca tcttactatg aggacgaaga gcttcgacca
    36961 cacccgcacc aaaactgatt tgcggcacaa aatgaccatc cataatatcg atatgggcat
    37021 actctgcccc agttgcttct aggcgtttaa tttcacgttc aaagttggca taatctgctg
    37081 ccagaattga cggagcaatc ttgtattgag acataggttt ctccttattt tggaattttt
    37141 ttgctgactt ttttataggt ttctctgcga ttttcaattt cgctgaggaa ttgcaggtag
    37201 ttgtcaaaac ggaagggcgc aatggtacct tcttcaactg ctggcttgac agcacaggac
    37261 ggctcatggg tatgggtaca agtacggaat ttgcagtctc gactgacagt ggcaatctct
    37321 ggaaaggcct gattgaggtc ttcagccgtt gatacttcat aatccagtga tgaaaagcct
    37381 ggtgtgtctg cgattttacc cccattgagg ttgtaaaaac taacagctcg agtggtatga
    37441 cgcccgcgac ccagactgtc tgaaatttct cccgtttcaa gattaagatc tggtgcgatt
    37501 ttattgagaa gagttgattt cccaacaccc gtctgcccca taaagaccgt aaccttgcct
    37561 gttaacaaag gcaggagttc ctctttactg gtcacaaagt catatccgat gtcaccatag
    37621 gtctgctggt aaaaatccag ttctcccccg tcttccaaca aatccatttt agaaatatag
    37681 acgatgggat gaataccctt atgctccaaa agaaccaaga aacgatccag caaattgctg
    37741 ttaaaatcag gttccttgac agacatgatt actacagctt ggtcgatatt gacaataggc
    37801 ggacggacca gactgttttt ccgttcgtga atcttgagaa tatagccttc tgaattttcc
    37861 tcggcagaga aatctaccca gtccccaacg taaggggtat gccctttttt acggaaattc
    37921 ccacgcgcgc gtgtttgata gacttggcca tcactctcta catagtagaa cccagccaag
    37981 gctttaatga tttgtccctg caaaataact cctttaaaat tgttagttcc attataacaa
    38041 aaaaaagcta ttttagctta gcttctcttt acaatttcga taagtctatt ctaaaagaaa
    38101 aagatacact cacgctttag ataccaagtt ttatacaaaa ataacgaatc tacctcctta
    38161 tataaaaaca ggcgaacaga gagcctaaaa ctccctgttc gctttacttt ttctgtgtgt
    38221 aatagaaaaa acctaataaa gcaagacaaa aaatatgaat ataaactcca tacatcatgt
    38281 ggggaaagac agactctata aaatagcctg gtagatagat gattggaaat tgatagaaat
    38341 cataggtcgt tagagatagt aaacaaagaa catacataaa tactgctaca attagaaccc
    38401 atccttgctt tcgccataga aaaatcatca ataagaacag acaaagtaga tagattgacc
    38461 aatttcgcaa cataaattga aaaccataaa tcatactttc agtcgtttct ccatcaatca
    38521 catcaactac tttatagaaa ggtaaacaat agctcactaa aaaaagaagg ggactaatta
    38581 tttttttcat attctctacc atggattatt ttgcaagtaa gctgaccatc tatctccata
    38641 tcgaatcaaa ttaacagtat aattagttac tacccgattt tcacctggtc caaccttaga
    38701 aaaacctgtg ctatactccc aactacttct tgcacctgga tgaaaccatt tttgctggga
    38761 tgaataccaa ccaccttgtc taacttccac acttgaagat tctatttcga tatccctttc
    38821 atggaagtca actcctccac ttattttagt aatatttttt tgtacacctc catcataact
    38881 cacccagtga acaacagtat acaattccac actataagta ctatcaaact gactttgatg
    38941 agtagtaatg ttttgagtat aagcgtgcac tttctgtata ccaaaaatat ggtctaatat
    39001 attcgttggt ttagcaagct tattgtaacc ctcttcaaca aaagtagcct tctctaaatc
    39061 agcggtataa acagtttttc cttgtactac ttgattgttt atagaagtaa tacggctatc
    39121 cacaacaatg ggggccacca tatctccatc gctagtttct attttagctg cctctttcac
    39181 ctcatataca actcgatttt cttcagactg aatcacttct accccatttt tttcaggtat
    39241 agataatcta gtttgcccat tagaaaccgt tatatttgga ccaatattct tctcatttgc
    39301 ataagtcgca ataggaaatc ctgatagaac cactgcacac ataaggctat tgactaattt
    39361 ttttctcatg aatatatcct tcccattttc aagaggagta aaaatagcta atataagatg
    39421 aacgtttcct tatatttcag aataggatat ctatctgaaa gcaattcaca ctcctataga
    39481 taactgttcc aaatcttggc tacatatatt tcaatagttt gctacaaaaa actcctttct
    39541 aagtctattg aacatgccct tattcaccta ctaatatatc acaaaaataa ataaatacaa
    39601 gactgttttt tctactagtt ttatgataga atagtattgt tagggtaaat ttcatatata
    39661 aatgtcgagt gaaaaatcga tggagcagaa atcggtagac aaagactcga tttcgttggt
    39721 ccagccccac aaggctaatc aggtatttca cgagtttaaa aatctaatga agtgcccaat
    39781 caactactga ttcattgatt taatacgaac tatagtggat tgaacctaga aatagtacac
    39841 taaggattct aaaacgtttc tagaaattaa tttgactttc ctaatctctt tgttcatatc
    39901 ttatttcaat ctactatata taccaaaatg ctaggacaaa agtctttaaa atcagagaaa
    39961 cgcatattat caggtgttgg aaaaccttga taatatgcgt tttatcatag aaagatctac
    40021 ttcatttttt actaaaatta agtttttgtc cctgcatctt agagtccttg ccctttaagt
    40081 gcatctgcta ggctggcaaa ctcttccaag ctgagagctt ccccacgcac acttggtgac
    40141 aagcctgctt ggtccaaagc cttggtcagc ttgtccttga cctcttcagt cttgccaaag
    40201 taacctgtca agttattcca caaggtcttg cggcgatggg taaaactagc cttggaaacc
    40261 ttaaagaaaa agttctcgtc ttccactgct acagctggca ctggacggcg caccattttc
    40321 aagatggctg agtctacatt tggtgctggc acaaagactg tacgcggcac gataaaggca
    40381 accttggctg tcatgtaata ctgcacagcg atagacaagc taccgtaagc cttggtattt
    40441 ggttgagccg agatacggtc cgccacttct ttttgcatca tgaccacaaa ctcactaaaa
    40501 ggaatgccac tctcgattaa gtgcatgaga ataggcgttg tgatgtagta aggcaaatta
    40561 gccactacct tgattggcag gtcaggattt ttgaaattct ggatatgttg cgccaaatcg
    40621 accttgagaa tgtcctcgtt gactacagtc acattgtcaa aatcacgcaa ggtatctgcc
    40681 aaaatcggta ccaaacgatg gtcgatctca aaggccataa cttctgctgc acgctcagcc
    40741 aaaaactcgg tcaaggcacc aatacctggc ccgatttcaa tgacattgac ctggtcatca
    40801 atctcagccg tatccacgat tttttgtagg atattggtat ccgtcaagaa attttgccca
    40861 aaggactttt taaaggtaaa accgtgacgc tccagcactg ccttggtcac gctataatct
    40921 gcaattctca tctattctct tttctattat ctgttactac tattgtaaca cattcccctt
    40981 gtattttggg ggtgaaaatc ataccaaaaa actatctttc ctcatgaaga aagatagtct
    41041 tggaaatctt taaaagtggc cttagcgctt ctctcgaaac atacgttcat actcttcgaa
    41101 aatctcttca aaccacgtca gcttcacctt gccgtactca agtacagcct gcggctagct
    41161 tcctagtttg ctctttgatt ttcattgagt atcaaaaaaa tcagcttctt gataacttcg
    41221 attttcgggt agggtcaaat ccacatcctc ctccacatca tccactgtca gttcaaccgt
    41281 ttgaggtaaa tttttcaaac gataatgctt ttgcctttgc ccttcactac tagcaaaatc
    41341 aagcaaatag ccatgcactc ggatttgaac caaaaggaga ggattggtca tattttccat
    41401 gatgaggata tcttataaac cacctctggc actaggataa tcagataccc tgcgaatacg
    41461 gattttttca cacatgagca agtttcctca tatcaatgat ttcatcagcc ttattccaga
    41521 ctaggggatt atgggtcgca atgatgataa ttcgattttc atctttcaaa tccaccaaga
    41581 gattcataac ctcctctgaa ttttcaggat caagagctgc tgttggttca tctgccaaaa
    41641 tcaagggtgg atttttcaaa atagttttcg caagggcaac tcgttgggcc tctcccccag
    41701 ataaagtata aattttttgt tctaaatcca aataccctag attaactttt tctaaagccc
    41761 ccacttgcct ttccaaacgt tctacttttg agattttctg accaacaaaa cccaaatcca
    41821 aattttcttt gattgattgg ttttctaaga ggccaaaatt ttgaaagaga tagcccatct
    41881 gatctcgaaa atactcacga gtgggaatgg tttttaaatc tttcccctga tagagaaccc
    41941 ttcctccatc tatcttttct agctttccca agatattcag cagcgtcgtc tttccgcttc
    42001 cactctttcc gattaaggca taaaccttgc ccttctccag cttgagattc aaaccagaga
    42061 aaatcgcgcg gtcattaaat ttcttttcca atccttgaat atcaatcatc ttattttcct
    42121 ttcaatactg ccatgctacc agcttcttct tttttgtcct gccttactaa aatcaagagg
    42181 gcgttaagcg taaacaaagc tacaactaga gcgctaatca aaccatctct tgtcaaaata
    42241 ctagatagga ctaggccaag caagagaact cctccttgcg ccagtaaata cttgccatga
    42301 agctcataga ttgtcatacc agcaagacgt ttaatcataa gctcccgtct gaactgctca
    42361 aaatagagaa gattcatgga atcaaataac aagatagccg tagacagggt caaaatcgtc
    42421 ccaataagga gagagtaaaa ctctacccgt ttgtcattta gtaccttggc aaaaaatagc
    42481 tggcttttta ccaagtaaga aaccttgtga tacagacctt gctcttttag agctgtgatg
    42541 ctgtctccat atcgatctag tttcaaggca ctattagccg tagttcccca caacatccct
    42601 gcaacaggtc ttgttccagt cgcttgcggc gttagaacta caataatcgg atcttttagg
    42661 tactggcgtg ttgtcttgta cccatcatta tagaggaaac gttcctgtcc tgtttctgta
    42721 aaagctagac ttacctgtgg gaggtagtat ttctgactcg tcacttctac actttcagat
    42781 gaaaagtttt gcaggtaatc tgtaaacaat ctttggtagt aggtagactg ctctcgcaag
    42841 ctctcaggca agattagccc aaactctccc tcagacaagt tttgcatctt gtccataaac
    42901 tctgaagaaa cggtaatctt ttcttctatc agatagcgtg gtgagacata gataacattc
    42961 cctgacggtg tgtagtcact gagacgattg ccatctaggt ccacttctgc tccgtctgag
    43021 aaattgtcaa cattgctcat aatataaaaa gagtctgtat tggctaaccg ttcttcagta
    43081 aatgtctgcc actcacgatt atccttacgc gttccttctt catcggcaaa tgcactagac
    43141 caaccaaagg atagacggta acggtctgag gactggctcc atttattgct agctctctcc
    43201 atttcctgca tttcacggta gtggggtagg agagctgtcg cactcgatcc gaccaccaat
    43261 acagctaaga gttgccccac catcatcaat gtcatcatac gtttgagagg gagtttccct
    43321 ttcaatagat ccaccagact attttcctgt aaaccaagta gatagacgac acttagtaag
    43381 gtagaaatcc ctgccagggt caatccataa agtagaagag caatgatgac cagttgcacc
    43441 gttgccataa acaaggcacc ttgataccag agaatcccca atcccaaaag actggatacc
    43501 agcactgagc agataaactg tctcacatct tctaacactg gtctgagagc aactccaaac
    43561 aagctctcac cagctattaa gcgaatccct gcctgacgaa gggatttgat ccgataaatc
    43621 agggtcagac tcataaaggt cagcagaaaa atagctaaac tcagtagcac cataggggtg
    43681 gccgccaata gtaagactat cgaaaatgga tcttctccat tcgaaacaaa gccttgatag
    43741 ccaagttctt tcaaggtggt ctgtaagctc actccatcca aacttcctga cacaatcaag
    43801 taagacccta ataaatcact cgtttctgca ctctccttgg aggaaatggt cagaccttct
    43861 ggaagctctc cctcaccata agtggcatag gtaaagagtg tttctccagc ttcatttggc
    43921 tcaacgattc gacgggcgat gagactatta tgctctaccg ccaagtgact caaaacctct
    43981 gtcacctctt cgcgactagc tactggttga tttatcatca ttcctgtcac atcaacagaa
    44041 ggatagttac caaataaaat ctcttctcga tggtcaacgg aagttatcac catataaagc
    44101 gataccaata ccattgaaat caaaataaat aaacgtttca tcatttcctc caaaaagtta
    44161 cttggtcact tagtgagaag gtgaccacag tcactgcgat gttaagaagc ttattaagtt
    44221 ctttctacta gcaacatctt caaatacatt atatccgttt tttcaagaac tatcaaggac
    44281 atcaatgtcc ttaaaatcta actatttcat attattttta gcttatatct aaaaaaacag
    44341 ttctaaagac gaactttaga actgttttga tacgaggaca aggacatttt tgtcactgat
    44401 tcactatgtt tataaatatt ttttgacatc ctcttgccat tcctctgtca atttctttac
    44461 tagaaatcca tctccaatta gcttcgcaaa tgttttagaa gactgataaa atgattcagc
    44521 taaactaaaa tctctttctt ctcttaatgc ttgcttccac aaaaacataa atacaagagg
    44581 tttcttttga taatcttgag ttttatccat aatttcttgt aaacacgata gataatcatt
    44641 aaaacaatca gttactccta ccttttcaag acaacacatt cctgaaataa gagtatctct
    44701 aattataaag aagttttcta atttagttac ctttttctgt tccaaaagaa agagcattag
    44761 cttttcgatt tgatttataa atttggcaag atcttttcta atgagcattt gataaaaaaa
    44821 caaacgaatc aacaacatat catttgttga ataaacttct ttttctatga tctgagacat
    44881 atgttcctca agtattaact ctgcatattc aggccttcta gttctagaag tatccaaaca
    44941 cgcctgcaat acttcacatg ctaattgttc ttctttagga agattatcaa agtatgtttt
    45001 ataaatctct tccaaacacg cttccttctt atcgtactcc tcttctttac catagattgg
    45061 ttcacgtaaa atctggtatt tcaattctaa ataagcagga ggaagagctg aaaaatccgg
    45121 cataaggcta taaactggaa ctcctagccg gcgagcaata taggctaact tgggcaaact
    45181 cggttgcgaa gctccacttt caattcgcga cagttgacga actgtcagtt cttgctcatc
    45241 tccacaaaaa tatggacgac taactccttt ttctatccga atctctttaa ttttttgacc
    45301 aattaacatc agacgcctcc tcttctacct gcttcgaaaa atactgtgaa acttaaaaaa
    45361 ttgtaacggc tacatctttc ctactcataa gatttcatag cttcttccac ttctgccaaa
    45421 gtaaccccaa acaactctag gcgtttgagg agttgcttgc cgttagaata gccgattcgg
    45481 agagtctctc cgagatattc tctacgctta cggctgtctg cccctgctag aaaaccaagg
    45541 cgaatcaagt cgctacgact aatgtcaaac tgactctcat gttcaaattg ttctgtcacc
    45601 tgagctagag ccgttttcag gtcttcatag ctggcatgct caattcccag agaacgcccc
    45661 ttggtcttgg actttggaac agcttcatct cgcttgagaa aggcatgccg aactgttgga
    45721 atggccgtca taatcatgcg ccgaatccgc tccccattaa aatctgggtc tgtaaagaca
    45781 atgactccat gacgttggtg caggcgctga atccgctcta tatcctgagc attgatggca
    45841 gaacctcgag tctcataggt ctccacatcg aaataacgtt tgagattgac cgtatcatca
    45901 cgcccttcaa ccacgataac ttgagaaatt ttctctttca ttacttgctg tccaatccaa
    45961 aaatgcgttc tgcatttgca gtcgttgcta ccgccagctc ttctgtcgtc ataccacgca
    46021 agtcagcgat aaagtcgacc acatagcgag tataggctgt tttattttca cgaccacgct
    46081 tgggtacagg tgctaagtaa ggcgcatctg tttccaccaa aatcttgtcc aaaggtaact
    46141 ctttagctgc ttcttggagg tcagttacct tcttaaaagt caccactcct gagaaggaaa
    46201 tggtcatacc aagatccaca aacttctctg cccactcaag cgtccctgaa aatgaatgca
    46261 tgataccacc acgaggacca acgccctcac tcttgataat ctcataggta tcttccagcg
    46321 catcacgggt atggacaaca aaaggcaaat ccaagtcctt agatagctga atctgacggc
    46381 gaaaaacctg ctcctgcacc tctttgggcg ctgtcatcca atggtaatct aagccaattt
    46441 cacctaaagc cacaaccttg ggatgtttta acttatccaa caagtaagcc tcaacttcct
    46501 ctgtataagt accagcttct gtaggatgcc aaccaatagt cgcatagagc tgatcatact
    46561 catctaccaa ctccaaggca cgctcaatcg tcggtttatc aaaaccaaca atattcatct
    46621 gtgtcacacc catctcagca gccaaggcaa tttcttctgc ctcacgacct gcaaattctt
    46681 ctacattcaa gtgtgtatgt gtatcaaaaa tcatctcttc taacctcgtt ttctatcttc
    46741 tattatacca aaaaagagga ggggcaccta atttttcggt ttcccctcct ctcttcaata
    46801 gagagctatt ctgctatctt ttctatccga tattgcccat ctcctattcc acagttagag
    46861 acagaagaga ttggctacat tgatagaata ttcctattca gctaaagtat gtgattatct
    46921 tgggttctca cttttctcac ccatcactag gattgatgac ttctcaaaat cccccttata
    46981 atctaacttt aagtagagaa tagaattttc tagctgttct attttctacg tctagtcttt
    47041 cttcctagca aagcaaaacc acttgttgcc accactagac caagactagc aagtgctgca
    47101 cttgatgctg aacctgtgtt aggtaattgt ttgccagcag gtgactggta ggtaacatct
    47161 tgcattgttc ctgcagttgc ttgcggtgca cttgttgtct taggagcagc attaggagcc
    47221 actggtctct taggaactgt aaccatgaca atggcttgca ctccaatcgt ttctgcttcc
    47281 ttcacatctt ccatagtttt cgcattttca atctctttga gagctgcttg tttttctgct
    47341 tccactcttg ctaaaagttc tgctttttct ttatcagaaa gcggtgcgcc tttgatttca
    47401 tcctgcttgt ccttggctgc tttttcaatg gcatttttag ctgattcttt ttcagtagct
    47461 aattgcttag aagcttgtga ttgagctgag ttttgtgaac ctgtgtgagc tgatccaccc
    47521 gcctggctac caccgcctgc attcgcatta gcatctgagc ttccagtatt gcctccctta
    47581 tctccacctg gtgtattttc tagcttatac tctggtgtag cttcttgagt tacagattca
    47641 cctttcgcag attgttgaac tgtatctttt cctagaatcg tcactactga accatctggg
    47701 aatgtgattg ttgctgtacc atctccagct acattgattg tcgctccgtc taatgctgaa
    47761 ccatttgctt gtaaaatagc aaccttaact ttttcttcat ctgttaaatg agttatatct
    47821 tttacatcta ctctttgagc aggtgcttta acagttgatt tttcagcagt cggtttagtg
    47881 ctatcttgtg cttttggatc ttgtgctacc aattgatttc ctggaattgt aatagctgaa
    47941 ccatctttaa agacgattgt cgctgcgcca tctccagcta cttcaacttt atagtaaaat
    48001 gaaataa
//
LOCUS       DAVBDR010000008        46209 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.008, whole genome shotgun sequence.
ACCESSION   DAVBDR010000008 DAVBDR010000000
VERSION     DAVBDR010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 46209)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 46209)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..46209
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.008"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            <1..128
                     /locus_tag="VQ540_000497"
     CDS             <1..128
                     /locus_tag="VQ540_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HET2544356.1"
                     /translation="FQSLNQLEQAIVDYIDYYNNKRIKVKLKGLSPVQYRTKSFG"
     gene            complement(257..460)
                     /locus_tag="VQ540_000498"
     CDS             complement(257..460)
                     /locus_tag="VQ540_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2544357.1"
                     /translation="MIKLYSPYAFLSKYLGAILLSFFCYYAKEIGCNNLTLSVWNDNE
                     GALRFYQRQGMKPQETTMEMIID"
     gene            complement(453..1535)
                     /locus_tag="VQ540_000499"
     CDS             complement(453..1535)
                     /locus_tag="VQ540_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HET2544358.1"
                     /translation="MSKLQQILTYLESEKLDVAVVSDPVTINYLTGFYSDPHERQMFL
                     FVLADQEPLLFVPALEVERASSTVSFPVVGYVDSENPWQKIKHALPQLDFKRVAVEFD
                     NLILTKYHGLKTVFETAEFDNLTPRIQRMRLIKSADEVQKMMVAGLYADKAVHVGFDN
                     ISLDKTETDIIAQIDFAMKREGYEMSFDTMVLTGDNAANPHGIPAANKVENDALLLFD
                     LGVLVNGYASDMTRTVAVGKPDQFKKDIYNLTLEAQQAALDFIKPGVTAHEVDRAARE
                     VIEKAGYGEYFNHRLGHGIGMDVHEFPSIMEGNDMVIEEGMCFSVEPGIYIPGKVGVR
                     IEDCGVVTKDGFDLFTSTSKDLLYFD"
     gene            complement(1661..2443)
                     /locus_tag="VQ540_000500"
     CDS             complement(1661..2443)
                     /locus_tag="VQ540_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HET2544359.1"
                     /translation="MVYTSLSSKDSNYPYQLNIAHLYGNLMNTYGDNGNILMLKYVAE
                     KLGAHVTVDIVSLHDDFDENHYDIAFFGGGQDFEQSIIADDLPAKKESIDNYIQNDGV
                     VLAICGGFQLLGQYYVEASGKRIEGLGVMGHYTLNQTNNRFIGDIKIHNEDFDETYYG
                     FENHQGRTFLSDDQKPLGQVVYGNGNNEEKVGEGVHYKNVFGSYFHGPILSRNANLAY
                     RLVTTALKKKYGQDIQLPAYEDILSQEIAEEYSDVKSKADFS"
     gene            complement(2443..3786)
                     /locus_tag="VQ540_000501"
     CDS             complement(2443..3786)
                     /locus_tag="VQ540_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HET2544360.1"
                     /translation="MNLKTTLGLLAGRSSHFVLSRLGRGSTLPGKVALQFDKDILQSL
                     AKNYEIVVVTGTNGKTLTTALTVGILKEVYGQVLTNPSGANMITGIATTFLTAKSSKT
                     GKNIAVLEIDEASLSRICDYIQPSLFVITNIFRDQMDRFGEIYTTYNMILDAIRKVPT
                     ATVLLNGDSPLFYKPTIPNPIEYFGFDLEKGPAQLAHYNTEGILCPDCQGILKYEHNT
                     YANLGAYICEGCGCKRPDLDYRLTKLVELTNNRSRFVIDGQEYGIQIGGLYNIYNALA
                     AVAIARFLGADSQLIKQGFDKSRAVFGRQETFHIGDKECTLVLIKNPVGATQAIEMIK
                     LAPYPFSLSVLLNANYADGIDTSWIWDADFEQITDMDIPEINAGGVRHSEIARRLRVT
                     GYPAEKITETSNLEQVLKTIENQDCKHAYILATYTAMLEFRELLASRQIVRKEMN"
     gene            complement(3885..5201)
                     /locus_tag="VQ540_000502"
     CDS             complement(3885..5201)
                     /locus_tag="VQ540_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000958936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HET2544361.1"
                     /translation="MLTYDLIVIGFGKAGKTLAGKLASAGKKVALVERSKAMYGGTCI
                     NIGCIPTKTLLVAAEKDLSFEEVIATKNTITGRLNGKNYATVAGTGVDIFDAEAHFLS
                     NKVIEIQAGDEKKELTAETIVINTGAVSNVLPIPGLATSKNIFDSTGIQSLDKLPEKL
                     GILGGGNIGLEFAGLYNKLGSKVTVLDALDTFLPRAEPSIAALAKQYMEEDGIELLQN
                     IHTTEIKNDGDQVLVVTEDETYRFDALLYATGRKPNVEPLQLENTDIELTERGAIKVD
                     KHCQTNVPGVFAVGDVNGGLQFTYISLDDFRVVYSYLAGDGSYTLEDRLNVPNTMFIT
                     PALSQVGLTESQAADLKLPYAVKEIPVAAMPRGHVNGDLRGAFKAVVNTETKEILGAS
                     IFSEGSQEIINIITVAMDNKIPYTYFTKQIFTHPTLAENLNDLFAI"
     gene            5394..6615
                     /locus_tag="VQ540_000503"
                     /pseudo
     CDS             5394..6615
                     /locus_tag="VQ540_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841575.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="OFA family MFS transporter"
     gene            6814..8388
                     /locus_tag="VQ540_000504"
     CDS             6814..8388
                     /locus_tag="VQ540_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HET2544362.1"
                     /translation="MKFNELNLSADLLAEIEKAGFVEASPIQEQTIPLALEGKDVIGQ
                     AQTGTGKTAAFGLPTLEKIRTEEATIQALVIAPTRELAVQSQEELFRFGRSKGVKVRS
                     VYGGSSIEKQIKALKSGAHIVVGTPGRLLDLIKRKALKLQDIETLILDEADEMLNMGF
                     LEDIEAIISRVPENRQTLLFSATMPDAIKRIGVQFMKAPEHVKIAAKELTTELVDQYY
                     IRVKEQEKFDTMTRLMDVAQPELAIVFGRTKRRVDELTRGLKIRGFRAEGIHGDLDQN
                     KRLRVLRDFKNGNLDVLVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KSGQSITFVAPNEMGYLQIIENLTKKRMKGLKPASVEESFQSKKQVALKKIERDFADE
                     TIRANFEKFGKDARKLAAEFTPEELAMYILSLTVQDPDSLPEVEIAREKPLPFKPSGN
                     GFGGKAKGGRGGRRGDDRRERDRRGNGRRDEFKKGSRGNDRFDKEKRYRKDNKKPRNT
                     LSEKQTGFVIRNKGDK"
     gene            8652..9440
                     /gene="codY"
                     /locus_tag="VQ540_000505"
     CDS             8652..9440
                     /gene="codY"
                     /locus_tag="VQ540_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HET2544363.1"
                     /translation="MAHLLEKTRKITSILKRSEEQLQDELPYNAITRQLADIIHCNAC
                     IINSKGRLLGYFMRYKTNTDRVEQFFQTKIFPDDYVQGANMIYETEANLPVEHDMSIF
                     PVESRDDFPDGLTTIAPIHVSGIRLGSLIIWRNDKKFEDEDLVLVEIASTVVGIQLLN
                     FQREEDEKNIRRRTAVTMAVNTLSYSELRAVSAILGELNGNEGKLTASVIADRIGITR
                     SVIVNALRKLESAGIIESRSLGMKGTYLKVLISDIFEEVKKRDY"
     gene            9440..10015
                     /locus_tag="VQ540_000506"
     CDS             9440..10015
                     /locus_tag="VQ540_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HET2544364.1"
                     /translation="MTKALISIDYTEDFVADSGKLTAGAPAQAISDAISKVTRLAFER
                     GDYIFFTIDAHEENDFFHPESKLFPPHNLIGTSGRNLYGDLGIFYQEHGSDSRVFWMD
                     KRHYSAFSGTDLDIRLRERRVSTVILTGVLTDICVLHTAIDAYNLGYDIEIVKPAVAS
                     IWPENHQFALGHFKNTLGAKLVDENLNELSE"
     gene            10097..10182
                     /locus_tag="VQ540_000507"
     tRNA            10097..10182
                     /locus_tag="VQ540_000507"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:10131..10133,aa:Leu,seq:aag)
     gene            10465..11595
                     /gene="ugpC"
                     /locus_tag="VQ540_000508"
     CDS             10465..11595
                     /gene="ugpC"
                     /locus_tag="VQ540_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HET2544365.1"
                     /translation="MVELNLKNIYKKYPNSEHYSVEDFNLNIKDKEFIVFVGPSGCGK
                     STTLRMIAGLEDITEGTASIDGVVVNDVAPKDRDIAMVFQNYALYPHMTVYDNMAFGL
                     KLRKYSKEDINKRVQEAAEILGLKEFLERKPADLSGGQRQRVAMGRAIVRDAKVFLMD
                     EPLSNLDAKLRVSMRAEIAKIHRRIGATTIYVTHDQTEAMTLADRIVIMSATKNPAGT
                     GTIGRVEQIGTPQEVYKNPVNKFVAGFIGSPAMNFINVKLVGSEIVSDGFRLKVPEGA
                     LKVLREKGYEGKELIFGIRPEDVNAEPAFLETFPDCVVKATISVSELLGSESHLYCQV
                     GKDEFVAKVDARDYLQTGATVELGFDLNKAHFFDVETEKTIY"
     gene            complement(11742..11888)
                     /locus_tag="VQ540_000509"
     CDS             complement(11742..11888)
                     /locus_tag="VQ540_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2544366.1"
                     /translation="MEIKEQTRKLAVSCSKYIFEVADKTDEISNHTYGKATLTWFEEI
                     FEEY"
     gene            12096..12854
                     /locus_tag="VQ540_000510"
     CDS             12096..12854
                     /locus_tag="VQ540_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001848902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HET2544367.1"
                     /translation="MSEAGHKFLAKLGKKRLRPGGKRATDWLIAEGGLSKEKRILEVA
                     CNRGTTAIELAQRFGCKITAVDMDAQALEVAKKSAGTAGVAHLISFERANAMKLPYQD
                     ASFDIVINEAMLTMQADQAKKKCVMEYLRVLKPGGLLLTHDVLLKEAKESIRQELSQA
                     IHVNVGPLTQDGWEQVMIESGYCDVKVLTGEMTLMKLSGMIYDEGWLGTLKICVNACK
                     KENRKQFLTMYKMFAKNKQKLGFIAMASYKSSKR"
     gene            12941..13453
                     /locus_tag="VQ540_000511"
     CDS             12941..13453
                     /locus_tag="VQ540_000511"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001049318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HET2544368.1"
                     /translation="MNLKDYIATIENYPKEGITFRDISPLMADGNAYSYAVREIVQYA
                     TDKKVDMIVGPEARGFIVGCPVAFELGIGFAPVRKPGKLPREVISADYEKEYGVDTLT
                     MHADAIKPGQRVLIVDDLLATGGTVKATIEMIEKLGGVMAGCAFLVELDELNGREKIG
                     DYDYKVLMHY"
     gene            13635..14579
                     /locus_tag="VQ540_000512"
     CDS             13635..14579
                     /locus_tag="VQ540_000512"
                     /EC_number="2.3.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine O-succinyltransferase"
                     /protein_id="HET2544369.1"
                     /translation="MPIRIDKKLPAVEILRTENIFVMDDQRAAHQDIRPLKILILNLM
                     PQKMVTETQLLRHLANTPLQLDIDFLYMESHRSKTTRSEHMETFYKTFPEVKDEYFDG
                     MIITGAPVEHLPFEEVDYWEEFRQMLEWSKTHVYSTLHICWGAQAGLYLRYGVEKYQM
                     DSKLSGIYPQDTLKEGHLLFRGFDDSYVSPHSRHTEISKEEVLNKTNLEILSEGPQVG
                     VSILASRDLREIYSFGHLEYDRDTLAKEYFRDRDAGFDPHIPENYFKDDDVNQVPCLC
                     WSSSAALFFSNWVNHAVYQETPFDWRKIEDDASAYGYL"
     gene            14588..15265
                     /locus_tag="VQ540_000513"
     CDS             14588..15265
                     /locus_tag="VQ540_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain-containing protein"
                     /protein_id="HET2544370.1"
                     /translation="MTYLDAFKSGTLVLPSALLLHFKELFPSSDDFLVWQFFYLQNTT
                     GLEEMSPSQIAERIGKEISDVNQSISNLTERGLLQYRTIELNGEIELLFDASLALERL
                     DDLFGAVRSSSDQLTPQNQLKDLVETFQQELGRLLTPFEIEDLTKTLKEDGTSADLIK
                     EALREAVLNGKPNWKYIQAILRNWRHEGIKSVAQIEAKRAEREASNPQLTQVSADFRN
                     AMDLWKD"
     gene            15363..16121
                     /locus_tag="VQ540_000514"
     CDS             15363..16121
                     /locus_tag="VQ540_000514"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000087908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HET2544371.1"
                     /translation="MSRKPFIAGNWKMNKNPEEAKAFVEAVASKLPSSDLVEAGIAAP
                     ALDLTTVLAVAKGSNLKVAAQNCYFENAGAFTGETSPQVLKEIGTDYVVIGHSERRDY
                     FHETDEDINKKAKAIFANGMLPIICCGESLETYEAGKAAEFVGAQVSAALAGLTAEQV
                     AASVIAYEPIWAIGTGKSASQDDAQKMCKVVRDVVAADFGQEVADKVRVQYGGSVKPE
                     NVASYMACPDVDGALVGGASLEAESFLALLDFVK"
     gene            16159..17664
                     /gene="lytC"
                     /locus_tag="VQ540_000515"
     CDS             16159..17664
                     /gene="lytC"
                     /locus_tag="VQ540_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_078138769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase LytC"
                     /protein_id="HET2544372.1"
                     /translation="MSVTFFIGEERLKTKIGLASICLLGLATSHVAANETEVAKTSQD
                     TTTASSSSEQNQSSNKTQTSTEVQTNAAAHWDGDYYVKDDGSKAQSEWIFDNYYKAWF
                     YINSDGRYSQNEWHGNYYLKSGGYMAQNEWIYDSNYKSWFYLKSDGAYAHQEWQLIGN
                     KWYYFKKWGYMAKSQWQGSYFLNGQGAMMQNEWLYDPAYSAYFYLKSDGTYANQEWQK
                     VGGKWYYFKKWGYMARNEWQGNYYLTGSGAMATDEVIMDGARYIFAASGELKEKKDLN
                     VGWVHRDGKRYFFNNREEQVGTEHAKKIIDISEHNGRINDWKKVIDENEVDGVIVRLG
                     YSGKEDKELAHNIKELNRLGIPYGVYLYTYAENETDAESDAKQTIELIKKYNMNLSYP
                     IYYDVENWEYVNKSKRAPSDTGTWVKIINKYMDTMKQAGYQNVYVYSYRSLLQTRLKH
                     PDILKHVNWVAAYTNALEWENPHYSGKKGWQYTSSEYMKGIQGRVDVSVWY"
     gene            18160..18678
                     /locus_tag="VQ540_000516"
     CDS             18160..18678
                     /locus_tag="VQ540_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HET2544373.1"
                     /translation="MVELKKEAVKDVTSLTKAAPVALAKTKEVLNQAVADLYVAHVAL
                     HQVHWYMHGRGFLVWHPKMDEYMEALDGQLDEISERLITLGGSPFSTLTEFLQNSEIE
                     EEAGEYRNVEESLERVLVIYRYLSELFQKGLDVTDEEGDDVTNGIFAGAKTETDKTIW
                     MLAAELGQAPGL"
     gene            18808..19314
                     /locus_tag="VQ540_000517"
     CDS             18808..19314
                     /locus_tag="VQ540_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HET2544374.1"
                     /translation="MTKKIVAIWAQDEEGVIGKENRLPWHLPAELQHFKETTLNHAIL
                     MGRVTFDGMGRRLLPKRETLILTRNPEEKIDGVATFQDVQSVLDWYQAQEKNLYIIGG
                     KQIFQAFEPYLDEVIVTHIHARVEGDTYFPEELDLSLFETVSSKFYAKDEKNPYDFTI
                     QYRKRKEV"
     gene            19516..20748
                     /gene="clpX"
                     /locus_tag="VQ540_000518"
     CDS             19516..20748
                     /gene="clpX"
                     /locus_tag="VQ540_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002874765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HET2544375.1"
                     /translation="MSTNRKNDMMVYCSFCGKNQEEVQKIIAGNNAFICNECVELAQE
                     IIREELVEEVLADLSEVPKPIELLHILNHYVIGQDRAKRALAVAVYNHYKRINFHDTR
                     EESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
                     ILLKLLQVADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGT
                     VASVPPQGGRKHPQQEMIQVDTKNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNNKAI
                     DENSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVRILKEPRNALVKQYQ
                     TLLSYDDVELEFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLV
                     RITKETVDGTDKPILETA"
     gene            20757..21344
                     /locus_tag="VQ540_000519"
     CDS             20757..21344
                     /locus_tag="VQ540_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002915299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HET2544376.1"
                     /translation="MELNTHNAEILLSAANKSHYPQDELPEIALAGRSNVGKSSFINT
                     MLNRKNLARTSGKPGKTQLLNFFNIDDKMRFVDVPGYGYARVSKKEREKWGCMIEEYL
                     TTRENLRAVVSLVDLRHDPSADDVQMYEFLKYYEIPVIIVATKADKIPRGKWNKHESA
                     IKKKLNFDPSDDFILFSSVSKAGMDEAWDAILEKL"
     gene            21355..21735
                     /locus_tag="VQ540_000520"
     CDS             21355..21735
                     /locus_tag="VQ540_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HET2544377.1"
                     /translation="MAKTIHTDKAPKAIGPYVQGKIVGNLLFASGQVPLSPETGEIVG
                     ENIQEQTEQVLKNIGAILAEAGTDFDHVVKTTCFLSDMNDFVPFNEVYQTAFKEEFPA
                     RSAVEVARLPRDVKVEIEVIAEIG"
     gene            21787..22677
                     /gene="rapZ"
                     /locus_tag="VQ540_000521"
     CDS             21787..22677
                     /gene="rapZ"
                     /locus_tag="VQ540_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HET2544378.1"
                     /translation="MTKKQLHLVIVTGMSGAGKTVAIQSFEDLGYFTIDNMPPALLPK
                     FLQLVEIKEDNPKLALVVDMRSRSFFSEIQAVLDELENQDGLDFKILFLDAADKELVA
                     RYKETRRSHPLAADGRILDGIKLERELLAPLKNMSQNVVDTTELTPRELRKTLAEQFS
                     DQEQAQSFRIEVMSFGFKYGIPIDADLVFDVRFLPNPYYLPELRNQTGVDEPVYDYVM
                     NHPESEDFYQHLLALIEPILPSYQKEGKSVLTIAMGCTGGQHRSVAFAKRLAQDLSKN
                     WSVNEGHRDKDRRKETVNRS"
     gene            22674..23651
                     /locus_tag="VQ540_000522"
     CDS             22674..23651
                     /locus_tag="VQ540_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HET2544379.1"
                     /translation="MRKPKITVIGGGTGIPVILKSLREKDVEIAAIVTVADDGGSSGE
                     LRKNMQQLTPPGDLRNVLVAMSDMPKFYEKVFQYRFSEDAGAFAGHPLGNLIIAGLSE
                     MQGSTYNAMQLLSKFFHTTGKIYPSSDHPLTLHAVFQDGTEVAGESHIVDHRGIIDNV
                     YVTNALNDDTPLASRRVVQTILESDMIVLGPGSLFTSILPNIVIKEIGRALLETKAEI
                     AYVCNIMTQRGETEHFTDSDHVEVLHRHLGRPFIDTVLVNIEKVPQEYMNSNRFDEYL
                     VQVEHDFVGLCKQVSRVISSNFLRLENGGAFHDGDLIVDELMRIIQVKK"
     gene            23648..24559
                     /gene="whiA"
                     /locus_tag="VQ540_000523"
     CDS             23648..24559
                     /gene="whiA"
                     /locus_tag="VQ540_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HET2544380.1"
                     /translation="MSFTVAVKEEILGQHHLSRHELSAIIKMSGSIGLSTSGLTLSVV
                     TENAKLARHLYESFLHFYEIKSEIRHHQRSNLRKNRVYTVFTDEKVQDLLSDLHLADS
                     FFGLETGIDEAILSDEEAGRAYLCGAFLANGSIRDPESGKYQLEISSVYLDHAQGIAS
                     LLQQFLLDAKVLERKKGAVTYLQRAEDIMDFLIVIGAMQARDDFERVKILRETRNDLN
                     RANNAETANIARTVSASMKTINNISKIKDIMGLENLPVDLQEVAQLRIQHPDYSIQQL
                     ADSLSTPLTKSGVNHRLRKINKIADEL"
     gene            complement(24593..25561)
                     /locus_tag="VQ540_000524"
     CDS             complement(24593..25561)
                     /locus_tag="VQ540_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000081018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HET2544381.1"
                     /translation="MSQLYDITIVGGGPVGLFAAFYAHLRQAKVQIIDSLPQLGGQPA
                     ILYPEKEILDVPGFPNLTGEELTNRLIEQLNGFDTPIHLNETVLEIDKQEEEFAITTS
                     KGSHLTKTVIIAMGGGAFKPRPLELEGVEGYENIHYHVSNIQQYAGKKVTILGGGDSA
                     VDWTLAFEKIAPTTLVHRRDNFRALEHSVQALQESSVTIKTPFAPSQLLGNGKTLDKL
                     EITKVKSDETETIDLDHLFVNYGFKSSVGNLKNWGLDLNRHKIIVNSKQESSQAGIYA
                     IGDCCYYDGKIDLIATGLGEAPTAVNNAINYIDPEQKVQPKHSTSL"
     gene            25697..26554
                     /locus_tag="VQ540_000525"
     CDS             25697..26554
                     /locus_tag="VQ540_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001867651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HET2544382.1"
                     /translation="MNFQQLSNLQYWTSLFASPWTIAINLIDILIVAYILYHFTKAIA
                     GTKIMILVRGVLVFILAQILANMIGLTTISWLINQIITYGVIAAVVIFSPEIRTGLER
                     LGRATDFFSNAPISAEEQMIRAFVKSVEYMSPRKIGALVAIQRVRTLQEYISTGIPLD
                     AKISAELLINIFIPNTPLHDGAVIIKEERIAVTSAYLPLTKNTGISKEFGTRHRAAIG
                     LSEVSDALTFVVSEETGGISITYNGRFKHNLTLDEFETELREILLPKEEVGLSFKERL
                     LGGWKHEKK"
     gene            26541..27320
                     /locus_tag="VQ540_000526"
     CDS             26541..27320
                     /locus_tag="VQ540_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbbR-like domain-containing protein"
                     /protein_id="HET2544383.1"
                     /translation="MKKNSLYIISSLFFACVLFVYATATNFQNSTSARQVKTETYTNT
                     VTNVPIDIRYNSDKYFISGFASEVSVVLTGANRLSLASEMQESTRKFKVTADLTDAGV
                     GTIEVPLSIEDLPNGLTAVATPQKITVKIGKKAQKDKVKIVPEIDPSQIDSRVQIENV
                     MVSDKEVSITSDQETLDRIDKIIAVLPTSERITGNYSGSVPLQAIDRNGVVLPAVITP
                     FDTIMKVTTKPVAPSSSTSNSSTSSSSETSSSTKATSSKTN"
     gene            27344..28696
                     /locus_tag="VQ540_000527"
     CDS             27344..28696
                     /locus_tag="VQ540_000527"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HET2544384.1"
                     /translation="MGKYFGTDGVRGEANLELTPELAFKLGRFGGYVLSQHETEAPKV
                     FVGRDTRISGEMLESALVAGLLSVGIHVYKLGVLATPAVAYLVETEGASAGVMISASH
                     NPALDNGIKFFGGDGFKLDDEKEAEIEALLDAEEDTLPRPSAEGLGILVDYPEGLRKY
                     EGYLVSTGTPLDGMKVALDTANGAASTSARQIFADLGAQLTVIGETPDGLNINLNVGS
                     THPEALQEVVKESGSAIGLAFDGDSDRLIAVDENGDIVDGDKIMYIIGKYLSEKGQLA
                     QNTIVTTVMSNLGFHKALNREGINKAVTAVGDRYVVEEMRKSGYNLGGEQSGHVILMD
                     YNTTGDGQLSAIQLTKIMKETGKSLSELAAEVTIYPQKLVNIRVENVMKEKAMEVPAI
                     KAIIEKMEEEMAGNGRILVRPSGTEPLLRVMAEAPTTEEVDYYVDTITDVVRAEIGID
                     "
     gene            28770..29144
                     /locus_tag="VQ540_000528"
     CDS             28770..29144
                     /locus_tag="VQ540_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HET2544385.1"
                     /translation="MNLKREQEFVSQYHFDARNFEWENENGAPETKVDVNFQLLQHDQ
                     ENQVTSLIVILSFMIVFDKFVISGTISQVNHIDGRIVNEPSELNQEEVETLARPCLNM
                     LNRLTYEVTEIALDLPGINLEF"
     gene            29146..29994
                     /locus_tag="VQ540_000529"
     CDS             29146..29994
                     /locus_tag="VQ540_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HET2544386.1"
                     /translation="MKLAVFTDSSAYLSEETLQREDLFVLDIPVNIDGEEYVEGINLS
                     AEEFYQKMAQASELPKTSQPSIAKLDEILTSLKEQGYTHALGLFLSSGISGFYQNIQY
                     MVDDYEGLTIAFPDTLITSAPLGIMVESVFNWRDQGDDFASIQDKLAIQISRTSAFIM
                     VDDLDHLVKGGRLSNGAAILGNLLSIKPILYFNDQGVIEVYEKVRTEKKATKRLIEII
                     KETTASGQYRVIVIHGNAPEKAEELRQHLLDFGLGSDVSLATFGSVIGTHLGAGSIAL
                     GYIPVI"
     gene            30271..31038
                     /locus_tag="VQ540_000530"
     CDS             30271..31038
                     /locus_tag="VQ540_000530"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HET2544387.1"
                     /translation="MSIRVIIAGFKGKMGQAACQMVLTDPDLDLVAVLDPFESESEWQ
                     GIPVFKDKADLAGFEADVWVDFTTPAVAYENTRFALENGFAPVVGTTGFTSEEIAELK
                     EFSRAQDLGGLIAPNFALGAVLLMQFATQAAKYFPNVEIIELHHDKKKDAPSGTAIKT
                     AELMAEVRESIQQGAADEEELIAGARGADFDDMRIHSVRLPGLVAHQEVIFGNQGEGL
                     TLRHDSYDRISFMTGVNLGIKEVVKRHELVYGLEHLL"
     gene            31050..32234
                     /locus_tag="VQ540_000531"
     CDS             31050..32234
                     /locus_tag="VQ540_000531"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001138849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HET2544388.1"
                     /translation="MPSEFQKALPVLEKIKEAGFEAYFVGGSVRDALLHSPIHDVDIA
                     TSSYPEETKQIFPRTADIGIEHGTVLVLDGDEEYEVTTFRTEDVYVDYRRPSAVSFVR
                     SLEEDLKRRDFTVNAFALDETGEIVDLFHGLEDLEKQVLRAVGVASERFNEDALRIMR
                     GFRFQASLGFALEPETFKAMKTLTPLLEKISVERTFVEFDKLLLAPFWRRGLASMIES
                     QAYDYLPDMASSQDKLNRLFDLETDFTFESSEQAWAALLWALEIENAQSFLKSWKTSR
                     QFAKQVQDLLIILALRENGELSKRDCYRFDIDLLLQAENLRQAQGKEVNPQAITEKYQ
                     SLTIHDKKEIQINGDILIKEYGYQPGPDLGEILTEIEFAIVDGELENNREAIHAYLRE
                     KK"
     gene            32231..34102
                     /locus_tag="VQ540_000532"
     CDS             32231..34102
                     /locus_tag="VQ540_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001279112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HET2544389.1"
                     /translation="MSDFIVEKLSKSVGDKTVFRDISFIIHDLDRIGLIGVNGTGKTT
                     LLDVLSGVSGFDGDVSPFSAKNDYQIGYLTQDPDFDDRKTVLDTVLSSELKEIQLIRE
                     YELIMLDYSEDKQARLERVMAEMDSLQAWEIESQVKTVLSKLGIQDLSTPVGELSGGL
                     RRRVQLAQVLLGNHDLLLLDEPTNHLDIAIIEWLTLFLKNSKKTVLFITHDRYFLDAL
                     STRIFELDRAGLTEYQGNYQDYVRLKAEQDERDAALLHKKEQLYKQELAWMRRQPQAR
                     ATKQQARINRFHDLKKEVSGSSAETDLTMNFETSRIGKKVIEFQAVSFAYENKPILQD
                     FNLLVQAKDRIGIVGDNGVGKSTLLNLIAGSLEPTKGQVVIGETVRIAYFSQQIEGLD
                     ESKRVINYLQEVAEEVKTSGGSTTSIAELLEQFLFPRSTHGTLIEKLSGGEKKRLYLL
                     KLLLEKPNVLLLDEPTNDLDIATLTVLENFLQGFAGPVLTVSHDRYFLDKVATKILAF
                     EDSKIRPFFGHYTDYLDEKAFETDMANQVQKVEKEKVVKVREDKKRMTYQEKQEWASI
                     EGDIETLEKRIAAIEEEMQANGSDFGKLATLQKELDEKNEALLEKYERYEYLSEFDS"
     gene            complement(34245..35429)
                     /gene="mntE"
                     /locus_tag="VQ540_000533"
     CDS             complement(34245..35429)
                     /gene="mntE"
                     /locus_tag="VQ540_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDF family manganese efflux transporter MntE"
                     /protein_id="HET2544390.1"
                     /translation="MKQSISNLKLAERGAIISISTYLILSAAKLAAGHLLHSSSLVAD
                     GFNNVSDIIGNVALLIGIRMARQPADRDHRFGHWKIEDLASLITSIIMFYVGFDVLRD
                     TIQKILSREETVIDPLGATLGIISAAIMFVVYLYNTRLSKKSNSKALKAAAKDNLSDA
                     VTSLGTAIAILASSFNYPIVDKLVAIIITFFILKTAYDIFIESSFSLSDGFDDRLLED
                     YQKAIMEIPKISKVKSQRGRTYGSNIYLDITLEMNPDLSVFESHEIADQVESMLEERF
                     GVFDTDVHIEPAPISEDEILDNVYKKLLMREQLIDQGNQLEELLTDDFVYIRQDGEQM
                     DKEAYKTKKELNSAIKDIQITSISQKTKLICYELDGIIHTSIWRRHETWQNIFHQETK
                     KE"
     gene            35733..38429
                     /locus_tag="VQ540_000534"
     CDS             35733..38429
                     /locus_tag="VQ540_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HET2544391.1"
                     /translation="MSKEQKRQAFYTQSPEEVLQAVDATEQGLSSSEAEKRLAEFGHN
                     ELEEGEKRSILVKFIEQFKDLMIIILVAAAILSVVTSGGEDIADAIIILAVVIINAAF
                     GVYQEGKAEEAIEALKSMSSPVARVLRDGHMAEIDSKELVPGDIVALEAGDVVPADLR
                     LIEANSLKIEEAALTGESVPVEKDLSVELATDAGIGDRVNMAFQNSNVTYGRGMGVVV
                     NTGMYTEVGHIAGMLQDADETDTPLKQNLNNLSKVLTYAILVIALVTFVVGVFIQGKN
                     PLGELLTSVALAVAAIPEGLPAIVTIVLSLGTQVLAKRHSIVRKLPAVETLGSTEIIA
                     SDKTGTLTMNKMTVEKVFYDAVLHDSADDIELGLEMPLLRSVVLANDTKIDVEGNLIG
                     DPTETAFIQYALDKGYDVKGFLEKYPRVAELPFDSDRKLMSTVHPLPDGRFLVAVKGA
                     PDQLLKRCLLRDKAGDIAPIDEKVTNLIHTNNSEMAHQALRVLAGAYKIIDSIPENLT
                     SEELENDLIFTGLIGMIDPERPEAAEAVRVAKEAGIRPIMITGDHQDTAEAIAKRLGI
                     IDANDTEGHVLTGAELNELSDEEFEKVVGQYSVYARVSPEHKVRIVKAWQKQGKVVAM
                     TGDGVNDAPALKTADIGIGMGITGTEVSKGASDMILADDNFATIIVAVEEGRKVFSNI
                     QKTIQYLLSANTAEVLTIFLSTLFGWDVLQPVHLLWINLVTDTFPAIALGVEPAEPGV
                     MNHKPRGRKASFFSGGVLSSIIYQGVLQAALVMSVYGLAIAYPVHVGDNHAIHADALT
                     MAFATLGLIQLFHAYNVKSVYQSILTVGPFKSKTFNWSILVSFILLMATIVVEPLEGI
                     FHVTKLDLSQWGIVMAGSFSMIIIVEIVKFIQRKLGFDKNAI"
     gene            38442..39233
                     /gene="yghU"
                     /locus_tag="VQ540_000535"
     CDS             38442..39233
                     /gene="yghU"
                     /locus_tag="VQ540_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-dependent disulfide-bond
                     oxidoreductase"
                     /protein_id="HET2544392.1"
                     /translation="MSAYQLPTVWQDEASNQGAFTGLNRPTAGARFEQNLPKGEQAFQ
                     LYSLGTPNGVKVTILLEELLEAGFKEAAYDLYKIAIMDGDQFGSDFVKLNPNSKIPAL
                     LDQSGTENVRVFESAHILLYLAEKFGAFLPSNPVEKVEVLNWLFWQAGAAPFLGGGFG
                     HFFNYAPEKLEYPINRFTMEVKRQLDLLDKELAQKPYIAGNDYTIADIAIWSWYGQLV
                     QGNLYQGSAKFLDASSYQNLVKWAEKIANRPAVKRGLEVTYTEIK"
     gene            39349..39759
                     /locus_tag="VQ540_000536"
     CDS             39349..39759
                     /locus_tag="VQ540_000536"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HET2544393.1"
                     /translation="MEKKIVKDILFLSQVSHPASQEDLYLARDLQDTLLANRDTCVGL
                     AANMIGMQKRVIIFNLGLVPVVMFNPVLLSFEGSYEAEEGCLSLVGVRSTKRYETIRL
                     AYRDSKWQEQTITLTGFPAQICQHELDHLEGRII"
     gene            39771..41366
                     /locus_tag="VQ540_000537"
     CDS             39771..41366
                     /locus_tag="VQ540_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000822862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2544394.1"
                     /translation="MKRIVFELIFIATTWYIFLPPLNLTSWEFLFFLCGHLLVVAILF
                     GFGKGINLVKTVHVRHGKAEAALNLEGFKINRLGKILLASIGGILLLAALVSLVTSSM
                     FQAKNYANVVTVTEKDFTEFPKSDTSKVPILDRSTAEKIGDRYLGSLTDKVSQYVAAD
                     TYTQLTIDGKPYRVTPLEYADPIKWFNNQAKGIGEYIKVDMVTGNADLVDLKTPIKYS
                     DSEYFNRDVKRHLRLKYPTKIFKTPSFEVDDEGNPFYVATVYQKQFGLAVPRPASVII
                     LDATNGETKEYSLSDVPEWVDRIYPAEETIEQINYNGKYKDGFLNAMISKKNVTQTTN
                     GYNYLSIGNDIYLYTGVTSANADESNLGFILENMRTGEITKYSLASATEESARESAEG
                     AVQEKSYKATFPILINLNDKPLYIMGLKDNAGLVKEYALVDAVEYQNVIVATTVEEML
                     SKYANKNDLEIDNATTESIKGVVADLKSAVIKGDTVYFFKVDGKIYKVKASVSDDLPY
                     LENGKTFEGQVGKDNYLKTFKVQ"
     gene            41533..41697
                     /locus_tag="VQ540_000538"
     CDS             41533..41697
                     /locus_tag="VQ540_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000508323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YczI family protein"
                     /protein_id="HET2544395.1"
                     /translation="MGFYLMVASMLLGLLALKIGFSQFKEKKDKFLSILTSLAGTALV
                     LVAVWLGWPK"
     gene            41776..42504
                     /gene="yaaA"
                     /locus_tag="VQ540_000539"
     CDS             41776..42504
                     /gene="yaaA"
                     /locus_tag="VQ540_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HET2544396.1"
                     /translation="MKILIPTAKEMNTDLPSIEAIPLKPESQTVLDALALYSASQLES
                     FYKVSAEKAAEEFQNIQALKRQTAQHYPALKLFDGLMYRNIKRDKLTEAEQDYLENHV
                     FITSALYGVVPALSPMAPHRLDFLMKLKVAGKTLKSHWKAVYDEALKKEEVIFSLLSS
                     EFETVFSKEIRAKMVTFKFMEDRGGQLKIHSTISKKARGAFLTALIENQVQTVGEARR
                     LNFAGFVYREDLSQPQGLVFVKEV"
     gene            complement(42555..44039)
                     /locus_tag="VQ540_000540"
     CDS             complement(42555..44039)
                     /locus_tag="VQ540_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003096885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET2544397.1"
                     /translation="MRNLLSTKVQRQLRLMETLIQNRNWMKLHELAEKLGCTERILKS
                     DLNELRIAFPSINIQSSVNGIMIDLEVNTSVEDIYQYFLANSQSFQLLEYMFFNEGLP
                     IYRTIENLYFSSANLYRLGRNITKVLSSQFQIELSFTPSEIRGNEIDIRYFFAQYFSE
                     RYYFLDWPFPDLPEEDLTEFADFFYKITNYPMRFSIYRMYKLMIAISIHRVKNGHFID
                     LPNHFYKEYYPLLKSIPNFQETLAYFSKHFGLEMTPDTIAQIFISFLQNDIFLDPQEF
                     FNSLEDNSQARYSYQLLSQILERLSKQYKITFTNHDELIWHLHNTAFFERQEIFSTPI
                     LFEQKALTIKKFEGYFPDFMGSARQELAQYRQAIGQHDHPEQLEHLMYTILTHAENLS
                     TQLLENRPPIKVLIISNFDHAISLTFVDMLSYYCNNRFTFDIWDELKTSPEILNQTDY
                     DIIVSNFYISGITKKFICRNHLSIMNLVNHLNTLSNEIHLSNTL"
     gene            44255..>46209
                     /locus_tag="VQ540_000541"
     CDS             44255..>46209
                     /locus_tag="VQ540_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HET2544398.1"
                     /translation="MKHSHKKSFDWYSMQQRYSIRKYYFGAVSVLLGTALVLGAAASV
                     QTVQAEENKQETTNSISVGRGEAATKPAEVSASNKEKTYAAPTVANPVETTPVKTGEV
                     TKPAEKVEEAKDKKEEVTHQDAIDKSKLLTALSRAKKLESKLYTEASAANLQTSIQAG
                     QSLLGKADASEAELSAAESSIQSSIIGLELRSNSNKGTVSETPVAKKANIVEAKEETN
                     PAATTDRSAVDSAVLPTSTAAKVETTSAPASINEILKPGLSLSDARQNPAIRKEDVDR
                     GYSGFRAAPAPTNQPVTNLGNNTVFTDISRGSHTFRGNGNSRRGNPIHFDVTTTRVRN
                     RVDFSIRYSGPGEFVNNNFILDKGNGFGEPSRATVSTPKLRDQVKNISKGGNFVSHSG
                     YSLEAAVETSTNQTIKFSLPIANPNGDLSVRLRPVTFNVGQGESGSATSNDPYSNSNY
                     YFREKPLLLDANPNGGTNNKTVSEDIDFQTVYLPTSKLPEGQTRLVREGEKGQRQIIY
                     KVHQLGNETILGLPISNSVIKEVKPRIMQIGVAKDLIDTVKPRVDQNKVGDTNNLTFY
                     LDNDGNGVYTEGVDELVQKIAIKDGAKGEKGDRGERGLTGAQGAKGEKGDRGERGLTG
                     AQGAKGEKGDRGERGLTGAQGAKGEKG"
BASE COUNT        13769 a         8550 c        10458 g        13432 t
ORIGIN      
        1 cgtttcagtc gcttaatcaa ttggaacaag ctattgtaga ctatattgat tactacaaca
       61 ataaacgaat taaggtaaaa ctaaaaggac ttagtcctgt gcaatacaga actaaatcct
      121 tcggataaat taattgtcta actgtttggg ggcagtacat attcaacacc tgatactatg
      181 cgttttattg tgggaagatt ttcctcattt tctagtgaaa ttgaactttt tctaacatct
      241 tttgatagat gacttcttaa tcaattatca tttccattgt tgtttcttgg ggtttcatcc
      301 cttgtctttg ataaaagcgg agagcaccct cgttatcatt ccagacactt agggttagat
      361 tattgcagcc aatttcttta gcataatagc agaaaaatga caataaaata gcccctagat
      421 attttgaaag gaaagcatag gggctatata gtttaatcaa aataaagcaa atctttgctg
      481 gtgcttgtaa agaggtcgaa gccatccttg gtaacaacac cgcagtcttc aatacgaaca
      541 ccgactttac cagggatata gatacctggt tcaacagaga agcacatgcc ttcttcgatg
      601 accatgtcgt ttccttccat gatagatggg aattcatgga catccatacc gataccatgc
      661 ccgagacggt ggttgaagta ctcaccataa ccagcttttt cgatgacctc acgggcagcg
      721 cggtccactt catgagcagt cacacctggc ttgataaagt caagagcagc ttgttgggct
      781 tcaagagtca agttgtaaat atctttcttg aattggtctg gtttgccgac agcgactgta
      841 cgagtcatat ctgacgcata gccattgacc agaacaccca ggtcaaagag gagaagagca
      901 tcattttcaa ccttattagc tgctggaatg ccgtgtggat tcgcagcatt atcaccagtc
      961 aagaccatgg tatcaaagct catttcataa ccttcacgtt tcatggcaaa gtcgatttgt
     1021 gcgatgatat ctgtctcagt cttatcaaga gaaatattgt caaaaccaac atgaacagcc
     1081 ttgtcagcat aaagacctgc aaccatcatt ttttgcactt catcagctga tttgatgagg
     1141 cgcatgcgtt ggatacgagg agtgaggttg tcaaactcag cagtctcaaa aactgttttc
     1201 aaaccatggt atttggtcaa gatgagattg tcaaactcaa cagcgacacg tttgaagtca
     1261 agttgtggaa gagcatgttt gattttttgc catggatttt cagaatcgac atagcccact
     1321 actgggaagg aaacggtgct acttgcacgt tctacttcaa gagctgggac aaagaggaga
     1381 ggttcctgat ccgctaggac aaagaggaac atttggcgtt catggggatc actgtaaaaa
     1441 ccagtgaggt aattgattgt gacggggtca gatacgacag cgacgtctag tttttctgat
     1501 tcaagatatg ttaggatttg ttgtaattta gacatatgct accttctttc tacccctcta
     1561 ttttggcaaa aaatgagaga aaatgcaagg gagaagggta aaagaaaaga caaaaaactc
     1621 cgacaagata acggagttct ttgatatcat tttcctttgt ttaagaaaag tcagccttgc
     1681 ttttgacgtc actgtactct tcagcgattt cttggctgag aatgtcctca taggcaggga
     1741 gttggatgtc ctgaccatat ttcttcttga gggcagtagt aactaggcga taagccagat
     1801 tggcattacg agagaggata ggcccgtgga agtaggaacc aaagacattc ttataatgaa
     1861 ccccttcacc gaccttttct tcgttgtttc catttccata gacaacctgt cccagcggtt
     1921 tttggtcatc agagaggaag gtacgacctt ggtgattttc aaatccatag taggtttcat
     1981 cgaaatcttc attgtgaatc ttgatgtcac cgataaaacg gttattggtc tggttgagcg
     2041 tgtagtgtcc catgacccct agcccttcga tacgttttcc tgaagcttca acataatatt
     2101 gacccaatag ttggaaacca ccgcagatag ccagaactac accgtcgttt tggatgtagt
     2161 tgtcaatgct ctctttttta gcaggtaggt cgtctgcaat gatactttgt tcaaagtctt
     2221 gaccaccacc gaaaaaggcg atgtcgtagt gattttcatc aaagtcatca tggagagaaa
     2281 cgatgtcaac ggtcacatgg gctcccagtt tttcagccac atacttgagc atgaggatgt
     2341 ttccattgtc cccgtaggta ttcatgagat ttccgtagag gtgggcaatg ttgagctgat
     2401 aggggtaatt gctatctttt gaggaaagtg aagtataaac cattagttca tctcctttct
     2461 aacaatctga cgactagcca gcagttcacg aaattccagc atggcagtat aagttgccag
     2521 aatataggca tgcttgcagt cttgattctc aatggtcttg agaacttgct ccagattact
     2581 cgtttcagtg attttctcag ctggatagcc agtcactcgg aggcgacgag cgatttcaga
     2641 atgacgaaca ccgccagcgt tgatttcagg aatgtccatg tcagtgattt gctcaaagtc
     2701 tgcatcccag atccagctag tgtcaattcc atctgcatag ttggcattaa ggaggacaga
     2761 taggctaaat ggataaggtg ctagtttgat catttcgata gcttgggttg caccgactgg
     2821 atttttaatc aagacaaggg tacattcctt gtcaccgata tgaaaggttt cttggcgtcc
     2881 aaagacagca cggctcttgt caaatccctg tttgatgagt tgggaatctg cgccgaggaa
     2941 acgggcgatg gccacagcag ctagggcgtt atagatatta tagagcccgc cgatttggat
     3001 accgtattct tggccgtcta tgacaaagcg agagcgattg ttggtcaact caaccagttt
     3061 tgtcaaacga tagtcgagat caggacgttt acatccacaa ccttcacaga tataggcacc
     3121 caagtttgca taggtattat gctcatattt gaggatgcct tggcagtcag gacagagaat
     3181 cccttcggta ttgtagtgag ccagttgggc tggtcctttt tccaagtcaa aaccaaaata
     3241 ctctataggg tttggaatag ttggcttgta gaaaagtgga ctgtctccgt taaggagaac
     3301 agtagcagtt ggaacttttc gaatggcatc caatatcatg ttataggtag tatagatttc
     3361 accgaaacgg tccatctggt cacggaagat attagtaatg acaaaaagac taggctggat
     3421 atagtcacag atacgagata gactggcttc gtcaatttcg aggacggcaa tatttttccc
     3481 agtttttgaa gatttggctg ttaggaaggt tgttgcaatc cctgtaatca tgttggcacc
     3541 gcttgggttg gttagaactt gaccataaac ctcttttaaa atgccgacag tgagggcagt
     3601 tgtcagggtt tttccatttg ttccagtgac aacgacaatc tcgtagttct tagctaggct
     3661 ttgtaaaata tctttatcaa attgaagggc gactttccct gggagcgtac ttccacgtcc
     3721 aagacggctt aaaacgaagt gggaagaacg cccagcaaga aggcccaaag tagtttttaa
     3781 gttcatgttt ctattatatc acaaaagagg gaaaagacag atttggtgtt tcgtagaagt
     3841 aaaaacagcc caaagagggc tgtcagttaa gatgagattt caacttaaat cgcaaacaag
     3901 tcattcaagt tctcagccaa ggttgggtga gtgaagattt gttttgtgaa gtaagtgtaa
     3961 ggaatcttgt tgtccatagc aacagtaatg atgttgatga tttcttgaga accttctgag
     4021 aagatgcttg caccaagaat ttcttttgtt tcagtattaa caacagcttt gaaagctccg
     4081 cgaaggtctc catttacgtg accacgaggc atggctgcaa cagggatttc tttcactgcg
     4141 tatggaagtt tcaaatcagc tgcttggctt tcagtcaaac caacttgtga aagtgcaggt
     4201 gtgatgaaca tagtatttgg cacattgaga cggtcctcaa gtgtgtagct gccatctcca
     4261 gcaaggtagc tgtaaacaac acggaagtca tcaagtgaaa tgtaagtaaa ttgaaggcca
     4321 ccgttgacat ctccaactgc aaagacacca ggaacgtttg tttgacagtg tttgtctact
     4381 ttaatagcac cacgttcagt tagttcaata tctgtatttt caagttgaag tggttctaca
     4441 tttggtttgc gtccagttgc gtagagaagg gcgtcgaaac ggtaagtttc gtcttcagtt
     4501 acgacaagca cttggtcacc atcgtttttg atttcagtag tatggatatt ttgaagcaat
     4561 tcaatgccat cttcttccat gtattgttta gcaagagctg cgatggaagg ttctgcacga
     4621 ggtaggaatg tatccaaggc atctaggact gtgaccttgc ttccaagttt gttgtaaagg
     4681 ccggcaaatt caagaccgat atttccgcca ccaaggattc caagtttttc aggtaatttg
     4741 tccaagcttt ggatacctgt tgagtcaaag atgtttttgc ttgtagcaag tccaggaatt
     4801 ggcaagacgt ttgaaacagc accagtgttg atgacgattg tttcagcagt cagttctttc
     4861 ttttcatcac cagcttggat ttcgatgact ttatttgaaa ggaagtgagc ttccgcatca
     4921 aagatatcta cgcctgtacc agcaacagtc gcatagtttt taccgttgag gcgaccagtg
     4981 atcgtgtttt tagtagcaat cacttcttca aaagacaagt ccttttcagc agcaactagc
     5041 aaggttttag ttgggataca accaatgttg atacaagttc caccgtacat agccttgctg
     5101 cgttcaacga gggcaacttt tttgccagct gaagccaatt tacctgctag tgttttacca
     5161 gctttaccaa atccaataac aattaaatcg tatgttaaca tttatcttcc tcctattcga
     5221 atttcattct agcacaagaa aaaaactttt gcacaattct gctacggaaa agacagaaaa
     5281 agataaaaac gctttccaga caaaaaacta gtaatttttt gacaagcttg ataaactaaa
     5341 atcctatcta tttttatata agaaagaata aatgttcgaa aataggaggt tttatgaaat
     5401 cgaatcgtta tattattgcc tttgctgggg tcattttaca cttaatgctg ggttcgactt
     5461 atgcttggag tgtttatcgt aaccctatta ttgaaaaaac gggatgggat caggcttctg
     5521 ttgccttcgc ctttagtcta gcaatctttt gtttgggctt atcggctgca tttatggggc
     5581 gtttggtaga aaaatttggt ccgaaagtca tggggagtct atctgctttt ctatacgcag
     5641 gtggaaatat cttaacagga tttgcaatag accgtcagga actgtggttg ttgtatctag
     5701 cttatggcat tttaggtggg cttggtttgg gagcaggcta tattacccct gtgtcaacga
     5761 ttataaaatg gtttcctgat aaacgtggtc tcgcaacagg tttagcgatt atggggtttg
     5821 gttttgcttc tttattgact agtcccatag cgcaacacct catcgcaggg gtagggattg
     5881 tagaaacttt ttatatttta ggagcaagtt actttattat catgctccta gcttcacaat
     5941 tcattaagcg tccaaatgag caagagcttg caattttatc ttcttcaggg aaagaaaaaa
     6001 cagcctcttt gacgcaagga atggctgcaa atcaggctct aaaaagcaat cggttttata
     6061 tgctttggat tattttcttt atcaacatag cttgtggttt aggcttaatt tcagcggcat
     6121 cgccaatggc acaggagatg gctggcttgt ctacaagtca tgcagcagta atggtgggtg
     6181 ttttggggat tttcaatgga tttggtcgct tgctctgggc gagtttgtct gactatatcg
     6241 gtcgccctct aacctttagt atattactgc ttgtcaatct tttctctctc actttggctc
     6301 tttacagatt ccgttttatt tgtagttgct atgtctattt tgatgacttg ctatggagct
     6361 ggtttttctt tgattccagc ttatctcagt gatatttttg gaaccaagga attggccgct
     6421 ctgcatggtt atattttaac agcttgggca atggctggtt tagcgggacc tattttatta
     6481 gcagagactt ataaaatggc tcattcgtac acacaaacct tgttcgtttt tctcatttta
     6541 tacagtatcg ccttggcttt gtcttattat ctaggtcgtt caatcaaaaa agaaagtcaa
     6601 aaaccgctta catgattttc tgtagaaatg gggctatctt ttgctctggt cttgtgttat
     6661 actagatagg ttgcaaagaa aacagtactt ttcttttgtg gaaaagaagc aacacgattt
     6721 tatatctagt tatatgaaaa tacgtcataa aaagaaaagt ataaactaag ccctataggg
     6781 tggcttcgca ccacctttag aaagaagaat aacgtgaaat ttaatgaatt aaacttgtct
     6841 gctgatttgc tagcagaaat tgaaaaagct ggttttgtag aagctagtcc tatccaagaa
     6901 caaactattc ctttggccct tgaaggcaag gatgttatcg gtcaagctca gactggtaca
     6961 ggaaaaactg cagcctttgg cttgcctacc cttgaaaaaa tccgtacaga agaagcgact
     7021 atccaagctt tggtcatcgc tccaactcgt gaactagctg tccaaagtca agaagaactc
     7081 ttccgctttg gtcgtagtaa gggagtcaaa gtccgttcag tatatggcgg atcaagcatt
     7141 gaaaaacaaa ttaaggctct taaatctggt gcccatatcg tggtgggaac tccaggtcgc
     7201 ctcttggact tgattaaacg caaggccttg aaattacaag acattgaaac ccttatcctt
     7261 gacgaagcgg atgaaatgct taacatgggc ttccttgaag acatcgaagc cattatttcc
     7321 cgtgtacctg agaaccgtca aactttgctt ttctcagcaa ctatgccaga tgccatcaaa
     7381 cgtatcggtg ttcagtttat gaaagcccct gaacatgtca agattgcggc taaggaattg
     7441 acaacagaat tggttgacca gtactatatc cgtgttaagg aacaagaaaa atttgacacc
     7501 atgactcgtc tcatggatgt ggcacaacca gaactcgcta ttgtatttgg tcgtaccaaa
     7561 cgccgtgtgg atgaattgac tcgtggtttg aaaattcgtg gcttccgtgc agaaggaatt
     7621 catggcgacc tagaccaaaa caaacgtctt cgtgtccttc gtgactttaa aaatggcaat
     7681 cttgatgttt tggttgcgac agacgttgca gcgcgtggtt tggatatttc aggtgtgacc
     7741 catgtctaca actacgatat tccacaagat cctgagagtt atgttcaccg tatcggtcgt
     7801 acaggtcgtg ctggtaagtc aggtcaatct attacttttg ttgctccaaa cgaaatgggt
     7861 taccttcaaa tcattgaaaa cttgactaag aaacgcatga aaggtctcaa acctgcaagt
     7921 gtagaagaat ccttccaatc aaaaaaacag gtagctctca agaaaatcga acgtgatttt
     7981 gcagatgaaa ccattcgtgc caactttgag aaatttggta aggatgctcg caaattggct
     8041 gctgagttta ctccagaaga attggcaatg tatatcttga gtctgacagt ccaagaccca
     8101 gatagccttc cagaagtgga gattgcacgt gaaaaaccac taccgtttaa accatcaggt
     8161 aatggtttcg gtggtaaagc taagggaggt cgtggaggcc gtcgtgggga cgaccgtcga
     8221 gagcgtgatc gccgtggcaa tggtcgccgt gatgagttca aaaaaggaag tcgtggcaac
     8281 gatcgttttg ataaggaaaa acgttaccgt aaggataata aaaaaccacg caatacttta
     8341 agcgaaaagc aaacaggctt tgttattcgt aacaaaggcg ataaataaga aaaagcggtt
     8401 caaaatgaat cgctttttta tataaggaga ccgaatgtga aaagacaaat aaaattacta
     8461 tattatcttt tataatgtta tgatacacaa aaataggcaa cttgtcaata gaaaaggaac
     8521 aatttaatta aaaatattct ggtttttaat taaattgtaa gtcaatgcaa gtcaataagg
     8581 aattttcaga taattattga aaaagagacg tttttatgtt ataatgatag cgattaaatt
     8641 cgaggtgaaa aatggcacat ttattagaaa aaactagaaa aattacatca attttgaaac
     8701 gctcagagga gcagttgcag gatgagctcc cttacaacgc tattacgcgt cagttagcgg
     8761 atattattca ttgcaatgcc tgcattatca atagtaaggg acgtctgctt ggctatttta
     8821 tgcgttataa aacaaataca gatcgcgtag agcaattctt ccaaactaag attttcccag
     8881 atgactacgt tcaaggggct aatatgattt acgaaacaga agcaaacttg cctgttgagc
     8941 atgatatgag tattttccct gttgagagta gagatgattt tccagatggc ttgacgacta
     9001 ttgcaccgat tcatgtatcg gggattcgcc ttggttcttt gattatttgg cgtaatgata
     9061 aaaaattcga agatgaggac ttggttcttg ttgagattgc cagtaccgtt gttgggattc
     9121 agcttcttaa cttccaacgt gaagaagatg agaaaaatat tcgtcgtcgt actgctgtca
     9181 ccatggcggt caataccctt tcttactccg aactccgtgc tgtttcagca attttagggg
     9241 aattaaatgg aaatgaaggg aagttgactg cgtcagtgat tgcagatcgt atcggaatca
     9301 ctcgctctgt gattgtcaat gctcttcgta aacttgagtc tgcggggatt attgaaagtc
     9361 gctcacttgg aatgaaggga acctatctta aggtcttgat ttcagatatt tttgaagaag
     9421 tgaagaaaag agattactaa tgacaaaggc tttaatttcg attgattata cagaagattt
     9481 tgttgctgat agtgggaagc tgacagcagg tgctccagct caggcgattt cggatgccat
     9541 cagcaaggta actcgattag cttttgaacg aggagattat atcttcttta ctattgatgc
     9601 tcatgaagaa aacgattttt tccatccgga aagtaagtta tttcctcctc ataatctgat
     9661 tgggacgagt ggacggaatt tatatggaga tttggggatc ttttatcaag agcatggttc
     9721 agacagtcgt gtcttttgga tggataaacg ccattactca gctttttcag ggactgacct
     9781 agatattcgt ttgagagagc gtagagtgtc taccgttatc ttaacaggtg tcttgacgga
     9841 tatctgtgtc ctacatacag ctatagatgc ctataatcta ggatatgaca tcgagattgt
     9901 taaaccagct gttgcttcca tctggcctga aaatcatcaa tttgccctag gtcatttcaa
     9961 aaatacactc ggagctaagt tagtagatga aaatctaaat gaactttctg agtaacctgg
    10021 ttggtgaaaa tgaaaaaatt tgaaaaaaag tgttgacaag catcccaaaa gttgatatac
    10081 tagtaaagta atcgatgcgg ggatggcgga attggcagac gcgcaggact aaggatcctg
    10141 tgaccgcttt aggtcgtgag ggttcaagtc cctctctccg cataggaaaa gagttagcta
    10201 aagctagctc ttttgtattt ctctaaaaaa ttagaatcca gtcaaatgta gtggagaatc
    10261 agcgaaaata tgggaaaact gttccttgtt tctgcttttg tcatagaaga ataataaaga
    10321 ttatcttctt caaattctcc gatattctct aaagttttgt gcaagttgca cagaactttt
    10381 ttattttttt ggtcatcttg ccatagaaat ataaagcgtt ttcatctata atataattat
    10441 caaaagacaa aaggagttca cctcatggta gaattgaatc ttaaaaatat ttacaaaaaa
    10501 tatccaaaca gcgaacacta ttcagttgaa gatttcaact tgaacatcaa agataaagaa
    10561 tttatcgttt tcgtaggacc ttcaggatgt ggtaaatcaa ctacactccg tatgattgct
    10621 ggtcttgaag acattacaga aggtactgca tctatcgatg gcgtggttgt caacgacgta
    10681 gctccaaaag accgtgatat cgccatggta ttccaaaact acgctcttta cccacacatg
    10741 actgtttatg acaacatggc tttcggtttg aaattgcgta aatacagcaa agaagacatt
    10801 aacaaacgtg ttcaagaagc agctgaaata cttggattga aagaattctt ggaacgtaaa
    10861 ccagctgacc tttcaggtgg tcaacgtcaa cgtgttgcca tggggcgtgc gattgtccgt
    10921 gatgcgaaag tattcttgat ggacgaacct ttgtcaaact tggatgccaa acttcgtgta
    10981 tcaatgcgtg ctgaaatcgc taaaattcac cgtcgtatcg gagctacaac tatctatgta
    11041 actcacgacc aaacagaagc gatgacactt gcagaccgta tcgttattat gtcagctact
    11101 aagaaccctg ctggtacagg tactatcgga cgtgtagaac aaatcggtac tcctcaagaa
    11161 gtttacaaaa atccagttaa caaattcgtt gcaggattca tcggaagccc agctatgaac
    11221 ttcatcaacg tgaaattggt tggtagcgaa attgtttctg acggtttccg tttgaaagtg
    11281 ccagaaggag cattgaaagt tcttcgtgaa aaaggctacg aaggaaaaga attgatcttt
    11341 ggtatccgtc cagaagacgt gaatgcagaa cctgctttcc ttgaaacatt cccagactgt
    11401 gttgtaaaag cgactatctc tgtatcagaa ctgcttggtt cagaatctca cctttactgc
    11461 caagttggta aagacgagtt tgttgcaaaa gttgatgctc gtgactactt gcaaacaggt
    11521 gcaacagttg agcttggatt tgacttgaac aaagcacact tcttcgatgt agaaactgaa
    11581 aaaacaatct actaaaataa ataaaattca aagcactaca agaaaagata tctctttatc
    11641 aattgtagtg gagagatatc agttaatcta gggagagaaa caaaatgctt ctctcctttt
    11701 tgctagggaa gtcatattat gcatctatat tgtgatgctc tttaatactc ttcgaaaatc
    11761 tcttcaaacc acgtcaacgt cgccttgccg tacgtatgat tactgatttc gtcagtttta
    11821 tctgcaacct caaagatgta ctttgagcag cttacggcta gtttcctagt ttgctctttg
    11881 atttccattg agtattattt gtgggtacca tctacaagtg aagctatatg cgtaaactac
    11941 gtgagcaatt gaattcgaac tagagaggta ataataaatt tatgctatag ttatggtgac
    12001 ttgtatgctt ttgattctag tttatcaaat aatagattag aattgtcaga taatatcatt
    12061 ttgtgttata atgaagaaaa aacagaggtg ttcaaatgtc agaagcaggt cataagtttt
    12121 tagcaaaatt ggggaaaaaa cgcttacgtc caggtggaaa gcgtgctaca gattggttaa
    12181 ttgcagaagg aggattgtca aaagaaaaga gaatactaga ggttgcgtgt aataggggaa
    12241 ctacagcaat tgagttggca cagcgttttg gttgcaagat aactgctgtt gatatggatg
    12301 ctcaagcttt agaagtggct aaaaaatctg ctggaacggc aggtgttgct catttaatca
    12361 gttttgaaag agcaaatgca atgaaacttc cttatcaaga tgctagtttt gatattgtta
    12421 taaatgaagc tatgctgact atgcaagccg atcaagctaa gaaaaaatgt gtaatggaat
    12481 atctaagggt attaaaacct ggaggtcttc ttttgacaca tgatgtgctt cttaaggaag
    12541 ctaaagagtc tatcagacag gaattatcac aagcaattca tgtaaatgta ggtcctttaa
    12601 ctcaagatgg ttgggaacag gtgatgatag aatcaggtta ttgtgatgtg aaagtattga
    12661 ctggtgaaat gacattaatg aaattatcgg gtatgattta tgacgaaggt tggctaggaa
    12721 ctttgaaaat ttgtgtaaat gcttgtaaaa aggagaatag aaagcagttt ttaactatgt
    12781 ataaaatgtt tgctaagaat aaacagaaat tgggctttat tgcgatggct agttataaat
    12841 cgtcaaaacg ttagataatt attgaagtta acttttcctt ttttctttct taaaaaatat
    12901 gctataatag agagtgaaaa actttgaaag aaagaaaaag atgaatttaa aagattacat
    12961 tgcaacaatt gaaaattatc caaaggaagg cattaccttc cgtgatatta gtcctttgat
    13021 ggctgatgga aatgcttata gctacgctgt tcgtgaaatc gttcagtatg ctactgacaa
    13081 gaaagtcgac atgatcgtgg gacctgaagc tcgtggattt atcgtgggtt gtccagttgc
    13141 ctttgagttg ggaattggtt ttgcgcctgt tcgtaagcca ggtaaattgc cacgcgaagt
    13201 tatttctgct gactatgaaa aagagtacgg tgtcgatacc ttgactatgc acgcggatgc
    13261 cattaagcca ggtcaacgtg ttcttattgt agatgacctt ttggcgacag gtggaactgt
    13321 taaggcaact atcgagatga ttgaaaaact tggtggtgtt atggcaggtt gtgccttcct
    13381 tgttgaattg gatgaattga acggccgtga aaaaatcggt gactacgact acaaagttct
    13441 tatgcattat taatgaaaac agtccctagg gctgttttct ctacactagg atataaaaat
    13501 agactataac tagttagaga aaaactataa ttgaaaacta tatcttcttg cagtataata
    13561 aaaggactaa gtgtttgaga tttgtcttca aacacatgca attattcctg agagagtaca
    13621 gttaggagag ggttatgccg attcgaattg ataaaaaatt gccagctgtt gagattttac
    13681 ggacagagaa tatctttgtc atggatgatc aacgtgctgc ccaccaagat atccgtcctt
    13741 tgaagatttt aattttaaat ctcatgccac agaaaatggt cacagagacc cagttgttgc
    13801 gtcacttggc taatacaccc ctacaactgg atattgattt tctctatatg gagagccacc
    13861 gttctaaaac aactcgttca gagcacatgg agaccttcta taaaactttt cctgaagtca
    13921 aggatgagta ttttgatggg atgatcatca cgggtgctcc agttgagcat ttaccatttg
    13981 aggaagtgga ctattgggag gaatttaggc agatgcttga gtggtctaag acacatgtct
    14041 attcgaccct tcatatctgt tggggggctc aggctgggct ttatctgcgc tatggtgtag
    14101 aaaaatacca gatggacagt aagctatcag gtatttatcc tcaggacacc ctaaaagagg
    14161 gtcaccttct atttagaggc tttgatgata gctatgtatc ccctcattca cggcacacgg
    14221 agatttctaa ggaagaggtc ttaaacaaga ccaatctcga gattttatca gaaggacctc
    14281 aggttggggt ttctattttg gccagtcgtg atttacgaga aatttatagt tttggtcatt
    14341 tggagtatga ccgtgatacc ttggcaaaag agtattttcg agatcgtgat gcaggtttcg
    14401 acccacatat tccagaaaat tactttaaag atgatgatgt taatcaggta ccttgtcttt
    14461 gttggtcttc atctgcagcc ctctttttca gtaattgggt aaaccatgcg gtctatcagg
    14521 agacgccttt tgattggaga aagatagaag atgatgcatc tgcatatggg tatttataag
    14581 aggaattatg acatatttag acgcttttaa atcaggtacc ttggttttac cgagtgccct
    14641 gctcttgcat tttaaggaac tctttccttc tagcgacgat tttctggttt ggcaattttt
    14701 ctatttgcaa aatacgacag gcttagaaga aatgtcgcca agccagattg ctgaaaggat
    14761 tggcaaggaa atttcggatg tcaaccagtc catttctaat ctgacggaaa ggggactgct
    14821 ccagtatcgt actatcgaat taaatggcga aattgaattg ctctttgatg ctagtttggc
    14881 cttggaacgt ttggatgacc tgtttggagc agttcgttca agttcagacc agctaacacc
    14941 tcaaaaccag ctcaaggatt tggtggaaac cttccagcag gagttgggac gattgttgac
    15001 gccttttgag attgaggatt tgaccaagac actaaaggaa gatggaacca gtgctgactt
    15061 gattaaggag gctcttcgtg aagctgtttt gaatggaaaa ccaaactgga agtacattca
    15121 ggcgattttg agaaactggc gccatgaagg aatcaagagt gtggctcaaa ttgaggccaa
    15181 gagagcagaa agagaagcaa gcaatcctca gttgacacag gtatctgcag atttcagaaa
    15241 tgccatggat ctctggaagg attaatccat gcaagtaggc ttgaaatccg agtaagattt
    15301 gcaagctgtg tataattgtg atagaataaa tagaaaataa attgaaaaaa gaggtatgtg
    15361 aaatgtcacg taaaccattt atcgctggta actggaaaat gaacaaaaat ccagaagaag
    15421 ctaaagcatt cgttgaagca gttgcatcaa aacttccttc atcagatctt gttgaagcag
    15481 gtatcgctgc tccagctctt gatttgacaa ctgttcttgc tgttgcaaaa ggctcaaacc
    15541 ttaaagttgc tgctcaaaac tgctactttg aaaatgcagg tgctttcact ggtgaaacta
    15601 gcccacaagt tttgaaagaa atcggtactg attacgttgt tatcggtcac tcagaacgcc
    15661 gtgactactt ccatgaaact gacgaagata tcaacaaaaa agcaaaagca atctttgcga
    15721 acggtatgct tccaatcatc tgttgtggtg aatcacttga aacttacgaa gctggtaaag
    15781 ctgctgaatt cgtaggtgct caagtatctg ctgcattggc tggattgact gctgaacaag
    15841 ttgctgcctc agttatcgct tatgagccaa tctgggctat cggtactggt aaatcagctt
    15901 cacaagacga tgcacaaaaa atgtgtaaag ttgttcgtga cgttgtagct gctgactttg
    15961 gtcaagaagt cgcagacaaa gttcgtgttc aatacggtgg ttctgttaaa cctgaaaatg
    16021 ttgcttcata catggcttgc ccagacgttg acggtgccct tgtaggtggt gcgtcacttg
    16081 aagctgaaag cttcttggct ttgcttgact ttgtaaaata atcagtaagt agcaaaagct
    16141 aggtggaaca gcattcagat gtctgttaca ttttttatag gagaggaaag attgaaaaca
    16201 aaaattggat tagcaagtat ctgtttacta ggcttggcaa ctagtcatgt cgctgcaaat
    16261 gaaactgaag tagcaaaaac ttcgcaggat acaacgacag cttcaagtag ttcagagcaa
    16321 aatcagtctt ctaataaaac gcaaacgagc acagaagtac agactaatgc tgctgcccac
    16381 tgggatgggg attattatgt aaaggatgat ggctctaaag ctcaaagtga atggattttt
    16441 gacaactact ataaggcctg gttttatatt aattcagatg gtcgttactc gcagaatgaa
    16501 tggcatggaa attactacct gaaatcaggt ggatatatgg cccaaaacga gtggatctat
    16561 gacagtaatt acaagagttg gttttatctc aagtcagatg gggcttatgc tcatcaagaa
    16621 tggcaattga ttggaaataa gtggtactac ttcaagaagt ggggttacat ggctaaaagc
    16681 caatggcaag gaagttattt cttgaatggt caaggagcta tgatgcaaaa tgaatggctc
    16741 tatgatccag cctattctgc ttatttttat ctaaaatccg atggaactta tgctaaccaa
    16801 gagtggcaaa aagtgggcgg aaaatggtac tatttcaaga agtggggcta tatggctcgg
    16861 aatgagtggc aaggcaacta ctatttgact ggaagtggtg ctatggcgac tgacgaagtg
    16921 attatggatg gtgctcgcta tatctttgcg gcctctggtg agctcaaaga aaagaaagat
    16981 ttgaatgtcg gctgggttca cagagatggt aaacgctatt tctttaataa tagagaagaa
    17041 caagtgggaa ccgaacatgc taagaaaatc attgatatta gtgagcacaa tggtcgtatc
    17101 aatgattgga aaaaggttat tgatgagaac gaggtggatg gtgtcattgt tcgtctaggt
    17161 tatagcggta aagaagacaa ggaattggcg cataacatta aggagttaaa ccgtctggga
    17221 attccttatg gtgtctatct ctatacctat gctgaaaatg agaccgatgc tgagagtgac
    17281 gctaaacaga ccattgaact tataaagaaa tacaatatga acctgtctta ccctatctat
    17341 tatgatgttg agaattggga atatgtaaat aagagcaaga gagctccaag tgatacaggc
    17401 acttgggtta aaatcatcaa caagtacatg gacacgatga agcaggcggg ttatcaaaat
    17461 gtgtatgtct atagctatcg tagtttatta cagacgcgtt taaaacaccc agatatttta
    17521 aaacatgtaa actgggtagc ggcctatacg aatgctttag aatgggaaaa ccctcattat
    17581 tcaggaaaaa aaggttggca atatacctct tctgaataca tgaaaggaat ccaagggcgc
    17641 gtagatgtca gcgtttggta ttaagcgatg atttgaaaga gggatgtgat agtagcaccc
    17701 tctttttctt tgttttatga tagttcatcc tcgagtaaat tcaagttctt gctcggaaat
    17761 gaagcttata tagtagattg aatatagaca aataccttgt gattggtaaa acattttaga
    17821 aattcattta cctttcctaa tcgacttggt ttcatcttat ttcaatctat tatagtattg
    17881 gggaatttct tcaaaccaca tcagcttggt cagttctacc tgcgacctca aaacttgtgc
    17941 tttggtcaag ctgggtttag tttcctagtt tgctgatgga tttccattga ctataagcat
    18001 ccaaccctct ttttgtcttc taaagaattc ttaaattatc agtctattgc aacttttctc
    18061 atataagttc tttgtcttgc tattggtttt ccttagtagt atactaaggt agtaatcatt
    18121 aagaagtggt tacaaaaaat aatgaatgag gtaaagaaaa tggtagaatt gaaaaaagaa
    18181 gcagtaaaag acgtaacatc attgacaaaa gcagcgccag tagcattggc aaaaacaaag
    18241 gaagtcttga accaagctgt tgctgatttg tatgtagctc acgttgcttt gcaccaagtg
    18301 cactggtata tgcatggtcg tggtttcctt gtatggcatc caaaaatgga tgagtacatg
    18361 gaagctcttg acggtcaatt ggatgaaatc agtgaacgct tgattacact cggtggaagc
    18421 ccattctcta cattgacaga gttccttcaa aatagtgaaa tcgaagaaga agctggtgaa
    18481 taccgtaatg ttgaagaaag cttggaacgt gttcttgtta tctaccgtta cttgtcagaa
    18541 cttttccaaa aaggtttgga tgtcactgat gaagaaggtg acgatgtgac aaacggtatc
    18601 tttgcaggcg ctaaaactga aacagataaa acaatttgga tgcttgcagc cgaacttgga
    18661 caagcacctg gtttgtaaga aataaggaaa catagataaa tctgtaggaa atttcttaca
    18721 gattttttct attttgtaag ctattccaaa ccagtctttt tttgagtttt ttgataaaat
    18781 agtactatca gtgaaaagga tggaagcatg actaagaaaa tcgtagctat ttgggcccag
    18841 gatgaagagg gtgtgattgg taaggaaaat cgtctgcctt ggcatttgcc agcagaattg
    18901 cagcacttta aagaaacaac tctgaatcat gctatcttga tggggcgtgt gacctttgat
    18961 gggatggggc gtcgcttgct tccaaaacgg gaaaccttga ttttgacgcg taatccggaa
    19021 gaaaagatag atggggttgc tacttttcag gacgtccagt ctgttcttga ctggtatcag
    19081 gctcaagaaa agaatctcta cattatcggt gggaagcaaa tttttcaggc ttttgaacct
    19141 taccttgatg aagtgattgt cactcacatt catgctcggg tggaaggaga tacctatttc
    19201 cctgaagaac ttgacttgtc tctttttgag acagtttcaa gcaaatttta cgccaaagat
    19261 gagaagaatc cttatgattt taccatccaa taccgcaaga gaaaggaagt ctaatggaac
    19321 ggagtttatt tggtctattc acggcttttc tgtgtttcat ctgctttctg gcaggagcac
    19381 aagcttttcg taaaaagcgt tacgggcttt ctatcctcct ttggttaaat gcctttacca
    19441 atctggtcaa tagtattcat gctttttaca tgaccttatt ttagatagaa tgacagtata
    19501 gaatggaagg aaatcatgtc tacaaataga aaaaatgata tgatggttta ttgctcattt
    19561 tgtggcaaaa accaagaaga agtacaaaaa ataattgctg gcaacaatgc ttttatttgt
    19621 aatgaatgcg tggagttagc tcaggaaatc attcgagaag aattggttga ggaagtcttg
    19681 gcagacttgt ctgaggtgcc aaaaccaatt gaactcctcc atatcttgaa ccactatgta
    19741 attggtcaag atcgtgccaa gcgtgccttg gcagtggcgg tttataacca ctacaaacgc
    19801 atcaatttcc acgatacacg cgaagagtca gaagatgtgg atttgcagaa gtcaaacatt
    19861 ttgatgattg gcccaactgg ttcagggaaa actttccttg cccagacctt ggctaagagc
    19921 ttgaatgtac cttttgctat tgcggatgcg acagctctga cggaggctgg ttatgtgggt
    19981 gaggatgtgg aaaatatact cctcaaactc ttgcaggttg ctgactttaa catcgaacgt
    20041 gcagagcgtg gcattatcta tgtggatgaa attgacaaga ttgccaagaa gagtgagaat
    20101 gtgtctatca cacgtgatgt ttctggtgaa ggggtgcaac aagcccttct caagattatt
    20161 gagggaactg ttgctagcgt accgcctcaa ggtggacgca aacatccaca acaagagatg
    20221 attcaagtgg atacaaaaaa tatcctcttc atcgtgggtg gtgcttttga tggtattgaa
    20281 gaaattgtca aacaacgtct gggtgaaaaa gtcatcggat ttggtcaaaa caataaggcg
    20341 attgacgaaa acagctcata catgcaagaa atcatcgctg aagacattca aaaatttggt
    20401 attatccctg agttgattgg acgcttgcct gtttttgcgg ctcttgagca attgaccgtt
    20461 gatgacttgg ttcgcatctt gaaagagcca agaaatgcct tggtgaaaca ataccaaacc
    20521 ttgctttctt atgatgatgt tgagttggaa tttgacgacg aagcccttca agagattgct
    20581 aataaagcaa tcgaacggaa gacaggggcg cgtggacttc gctccatcat cgaagaaacc
    20641 atgctagatg ttatgtttga ggtgccgagt caggaaaatg tgaaattggt tcgtatcact
    20701 aaagaaactg tcgatggaac ggataaaccg atcctagaaa cagcctagag gtgactatgg
    20761 aacttaatac acacaatgct gaaatcttgc tcagtgcagc taataagtcc cactatccgc
    20821 aggatgaact gccagagatt gccctagcag ggcgttcaaa tgttggtaaa tccagcttta
    20881 tcaacactat gttgaaccgt aagaatctcg cccgtacatc aggaaaacct ggtaaaaccc
    20941 agctcctgaa cttttttaac attgatgaca agatgcgctt tgtggatgtg cctggttatg
    21001 gctatgctcg tgtttctaaa aaggaacgtg aaaagtgggg gtgcatgatt gaggagtact
    21061 taacgactcg ggaaaatctc cgtgcggttg tcagtctagt tgaccttcgt catgacccgt
    21121 cagcagatga tgtgcagatg tacgaatttc tcaagtatta tgagattcca gtcatcattg
    21181 tggcgaccaa ggcggacaag attcctcgtg gtaaatggaa caagcatgaa tcagcaatca
    21241 aaaagaaatt aaactttgac ccaagtgacg atttcatcct cttttcatct gtcagcaagg
    21301 cagggatgga tgaggcttgg gatgcaatct tagaaaaatt gtgaggaaaa gaaaatggca
    21361 aaaacaattc atacagataa ggccccaaag gctatcggac cctatgttca aggaaaaatc
    21421 gttggcaacc ttttgtttgc tagcggtcaa gttcccctat cccctgaaac tggggaaatt
    21481 gtaggagaga atatccaaga acagacagag caagtcttga aaaacatcgg tgctattttg
    21541 gcagaagcag gaacagactt tgaccatgtt gtcaaaacaa cttgcttctt gagcgatatg
    21601 aacgactttg ttccttttaa tgaggtttac caaacggcct tcaaagagga attcccagct
    21661 cgttcagctg tggaggtagc tcgtcttcct cgtgatgtaa aagtcgaaat tgaagtcatc
    21721 gcagagattg gataagctag ttgaagtttg gtgttgccaa acttcttttg atataaggag
    21781 aaaaagatga caaagaaaca acttcacttg gtgattgtga cagggatgag tggcgcaggg
    21841 aaaactgtag ccattcagtc cttcgaggat ctaggttatt tcaccattga taatatgccg
    21901 ccagctctct tgcctaagtt tttgcagctg gttgaaatta aggaagataa tcctaagttg
    21961 gctttggtag tggatatgcg tagccgttct ttcttttcag agattcaagc tgttttggat
    22021 gagttggaaa atcaagatgg tttggatttc aaaatcctct ttttggatgc ggctgataag
    22081 gaattggtcg ctcgttacaa ggaaaccaga cggagtcacc cactagcagc agacggtcgt
    22141 attttagatg gaatcaagtt ggaacgtgaa ctcttggcac ctttgaaaaa tatgagccaa
    22201 aatgtggtgg atacgactga actcactcca cgtgaactgc gcaaaaccct tgcagagcag
    22261 ttttcagacc aagaacaagc ccagtctttc cgtatcgaag tcatgtcttt cggatttaag
    22321 tatggaatcc cgattgatgc ggacttggtc tttgatgtcc gtttcttgcc aaatccctat
    22381 tatctaccag aactgagaaa ccaaacgggt gtggatgaac ctgtttatga ttatgtcatg
    22441 aaccatcctg agtcagaaga cttttatcaa catttattgg ccttgattga gccgattctg
    22501 ccaagttacc aaaaggaagg taagtccgtt ttgaccattg ctatgggatg tacgggtgga
    22561 caacaccgta gtgtggcatt tgctaaacgc ttggcgcagg acttatccaa gaattggtct
    22621 gttaatgaag ggcatcgcga caaagaccgc agaaaggaaa cggtaaaccg ttcatgagaa
    22681 aaccaaagat aacggtgatt ggtggaggga ctggaattcc cgtcattcta aaaagtctgc
    22741 gggaaaaaga tgtggaaatc gcagctatcg tgacggtggc agatgatggt ggttcttcag
    22801 gtgaactccg aaaaaatatg caacagttga caccgccagg tgatcttcgt aatgtccttg
    22861 tggccatgtc ggatatgcct aagttttatg agaaggtctt tcagtatcgg ttctctgagg
    22921 atgccggagc ctttgctggc catccattgg gaaatctcat cattgctggc ttgtcagaaa
    22981 tgcagggttc aacctataat gccatgcagt tattgagcaa atttttccat acaacaggga
    23041 aaatttatcc ttccagtgac catcctttga cccttcatgc agtctttcag gatgggacag
    23101 aagtggctgg agagagtcat attgtagacc atcgaggcat aattgacaat gtctatgtga
    23161 ccaatgccct aaacgatgat acgcctctgg ccagccgtcg agtagtgcag accatccttg
    23221 aaagtgacat gattgtccta gggccaggtt ccctctttac ctctattttg cccaatatcg
    23281 tgattaagga aattgggcgg gctcttttgg aaactaaggc agaaattgcc tatgtctgca
    23341 atatcatgac ccaacgtggg gagacggaac actttacaga tagcgaccac gtggaagtct
    23401 tgcatcgtca ccttggtcgc ccttttatcg acactgtctt ggtgaatatt gaaaaagtgc
    23461 ctcaggaata catgaattcc aaccgttttg atgaatactt ggtgcaagtg gaacacgatt
    23521 ttgtaggtct ttgtaagcaa gtttcgcgcg tgatttcatc taacttcctt cgtctggaaa
    23581 atggcggtgc cttccacgat ggagatttga ttgtggacga gttgatgcgc attatacagg
    23641 tgaaaaaatg agtttcacag tagcagtaaa agaagaaatc ctgggccaac accatctgag
    23701 ccggcatgaa ttatctgcca ttatcaaaat gtctggtagc atcggtctct cgacttcggg
    23761 cttgactttg tcagttgtga cagaaaatgc caaactggcc cgtcacctct atgagtcctt
    23821 tctccatttc tatgaaatca aatctgaaat tcgtcaccac caacggagca atcttcgcaa
    23881 gaatcgcgtc tataccgttt ttacagatga aaaggtgcag gatttgttaa gtgatttgca
    23941 cttggcagac tctttctttg gcctggaaac aggtattgat gaggcgattt tatcggatga
    24001 ggaagcaggt cgtgcctatc tctgtggcgc tttcttggca aatgggagca ttcgtgaccc
    24061 tgagtcaggc aagtaccagt tggaaatcag ttctgtttat ctggaccacg cgcaaggaat
    24121 tgcctccctt ctccaacagt ttttactgga tgccaaggtg cttgagcgca agaagggggc
    24181 tgtgacctat ctccagcgag cagaagacat tatggacttc ttgatagtaa tcggagccat
    24241 gcaggcacgt gatgattttg agcgggttaa gattttgcga gaaacccgta acgacctcaa
    24301 tcgggctaat aatgccgaga cagctaatat cgctcggaca gtttctgcca gcatgaagac
    24361 cattaacaat atcagtaaaa taaaagatat catgggctta gaaaatttgc cagtagattt
    24421 gcaggaagtg gcgcaactga ggattcagca cccagactac tctatccagc agttagcaga
    24481 tagtctcagc acccctctga ccaaaagtgg tgtcaatcac agactcagaa aaatcaataa
    24541 gatagcggat gaattataaa accacgaatc ctatgtgact cgtggttctt ttttataaac
    24601 tggtagagtg ttttggttgt actttttgtt cagggtcaat gtagttgata gcgttgttga
    24661 cagcagttgg agcttctccg aggcctgtcg caatcagatc aatttttccg tcatagtagc
    24721 agcagtcacc gatagcatag atacctgctt ggctggattc ctgtttgctg ttgacgataa
    24781 tcttgtgacg gttgaggtcg agcccccagt ttttaaggtt accgacagaa gatttgaaac
    24841 catagttgac aaagaggtgg tctaggtcaa tggtttcagt ttcatcagat ttgacttttg
    24901 tgatttcaag tttatcaagt gtttttccat ttccaaggag ttggctaggg gcgaatggtg
    24961 tcttgatggt tacagatgat tcttgcaagg cttgaacact gtgttccaag gcacggaaat
    25021 tatctctgcg gtgaacaagg gtagttggtg cgattttttc aaaagccaaa gtccaatcca
    25081 cagccgagtc tcccccacca agaatcgtca cttttttacc agcgtattgc tgaatgttag
    25141 aaacgtggta gtggatattt tcatagccct caaccccttc aagttccagc ggacgtggtt
    25201 tgaaggcacc gccacccata gcgatgataa ctgttttagt caggtgactt cctttagaag
    25261 ttgtgatggc aaattcttct tcttgtttgt caatctcaag aaccgtttca ttgagatgaa
    25321 taggggtatc aaatccattt agctgttcaa tcaagcggtt agtcaactct tctccagtca
    25381 ggtttgggaa gcctggtacg tctaggattt ccttttcagg gtagagaata gcaggttgtc
    25441 cacctagctg gggaagagag tcgatgattt gaaccttggc ttggcgtagg tgggcataaa
    25501 aggctgcaaa aagcccgaca ggaccaccac ccacaatggt aatatcatag agttgagaca
    25561 tagtttctcc tttgtttttt ctagtcagtt tattttatca tatttttgtt caatgtaaaa
    25621 tggactagga tagggaaaaa aatgccagaa aatggtataa taggacgaaa gtgttttgat
    25681 agggaggata tcagggatga attttcaaca attatccaat ttgcaatatt ggaccagttt
    25741 gtttgcaagt ccatggacga tagctatcaa tctgattgat attttgattg ttgcttatat
    25801 tttataccat tttacaaaag ctattgcagg aaccaagatt atgattttgg tacgtggagt
    25861 tttggtattt attttagctc aaatccttgc aaatatgatt ggtttgacta cgatttcttg
    25921 gttaatcaat caaattatta cttatggggt tattgcggcg gttgttatct tctctccaga
    25981 gattcggact ggtttggaac gtttgggaag agcgacagat ttcttttcca atgcccctat
    26041 tagtgctgag gaacagatga ttcgtgcctt tgttaagtct gttgaataca tgagtcctcg
    26101 taaaatcggg gccttggttg ctattcagcg tgtacgtacc ttgcaggagt atatttcgac
    26161 aggaattccc ttggatgcta agatttctgc agaacttctc attaacattt ttattcccaa
    26221 cactccccta catgacggtg cggtgattat caaagaagaa cgtatcgctg tgacgtctgc
    26281 ctatctgccc ttgacaaaaa acacagggat ttccaaggaa tttgggacca gacaccgggc
    26341 ggctatcggt ttatcagaag tctcagatgc cttgactttt gtcgtatcag aggaaacggg
    26401 aggaatttcg ataacctata atggaaggtt taagcacaac ctaacacttg atgaatttga
    26461 aacagaatta cgtgaaatct tacttccaaa agaggaagta ggtcttagtt ttaaagaacg
    26521 attgctagga ggatggaaac atgaaaaaaa atagtttata tatcatatcc tcactctttt
    26581 ttgcttgtgt cttatttgtc tatgctacgg cgacgaattt tcaaaacagt accagtgcta
    26641 ggcaggtaaa aacggaaacc tatactaata cagtaacaaa tgtccctatt gacatacgct
    26701 ataatagtga taagtatttt attagcggtt ttgcttcaga agtatcagtg gtcttgactg
    26761 gtgcaaatcg cctatcgcta gctagtgaaa tgcaagaaag tacacgtaaa ttcaaggtta
    26821 ctgctgacct aacagatgcc ggtgttggaa caattgaagt tcctttgagc attgaagatt
    26881 tacccaatgg gctgaccgct gtggcgactc cgcaaaaaat tacagtcaag attggtaaga
    26941 aggctcagaa ggataaggta aagattgtac cagagattga ccctagtcaa attgatagtc
    27001 gggtacaaat tgaaaatgtc atggtgtcag ataaagaagt gtcgattacg agtgaccaag
    27061 agacattgga tagaattgat aagattatcg ctgtcttgcc aactagcgaa cgcataacag
    27121 gtaattacag tggttcagta cctttgcagg caatcgaccg caatggtgtt gtcttaccgg
    27181 cagttatcac tccgtttgat acaataatga aggtgactac aaaaccagta gcaccaagtt
    27241 caagcacatc aaattcaagt acaagcagtt catcggagac atcttcgtca acgaaagcaa
    27301 ctagttcaaa aacgaattaa aaatagaaaa ggattttata acaatgggta aatattttgg
    27361 gactgatgga gtccgtggag aagctaacct agaactaaca ccagaattag cctttaaact
    27421 aggacgtttt ggaggctatg ttcttagtca acatgaaacg gaagcgccga aagtctttgt
    27481 aggacgtgac acacgtattt caggggaaat gctagaatcg gccttggtgg caggtctcct
    27541 ttcagtaggg attcacgtat acaaacttgg tgtccttgca acaccagcag tagcttactt
    27601 ggttgaaact gaaggagcaa gtgctggtgt catgatttct gctagccaca atccagctct
    27661 tgataacgga atcaagttct ttggcggtga tggcttcaaa ctagatgatg aaaaagaagc
    27721 agaaattgaa gccttgctag atgctgagga agacactctt cctcgtccaa gtgcagaagg
    27781 cttaggaatt ttggtagatt atccagaagg cttgcgtaag tatgaaggat accttgtttc
    27841 aactggaact cctcttgatg gaatgaaggt tgccttggat acagctaatg gagcagcttc
    27901 taccagtgcc cgtcaaatct ttgcagacct tggtgcccaa ttgacggtta tcggggaaac
    27961 accagacggt cttaacatca accttaatgt tggttcaaca catccagaag cccttcaaga
    28021 agtggtcaaa gaaagtgggt cagctattgg tttggccttt gatggagaca gtgaccgctt
    28081 gattgctgtt gatgagaatg gtgacatcgt cgatggtgac aagattatgt acatcatcgg
    28141 aaaatacctt tctgaaaaag gacaattggc tcaaaataca attgtgacaa ctgttatgtc
    28201 taaccttggt ttccacaagg ccttgaatcg cgaaggtatt aacaaggcag ttactgcagt
    28261 tggtgaccgc tacgttgttg aagaaatgag aaaatcaggt tacaaccttg gtggtgaaca
    28321 gtctggtcac gttatcttga tggattacaa taccacaggt gatggtcaat tatcagcaat
    28381 tcaattgact aaaatcatga aggaaactgg taagagctta tcagagttgg cggcagaagt
    28441 aacgatttat ccacaaaaat tagttaatat ccgagtggaa aacgtcatga aggaaaaggc
    28501 catggaagtg ccagctatca aggccatcat cgagaagatg gaagaagaaa tggcggggaa
    28561 cggccgtatc cttgttcgtc caagtggaac agagcccctc ttgcgtgtta tggcagaagc
    28621 gcctacaaca gaagaagtgg actactatgt tgatactatc acagatgtag ttcgtgctga
    28681 aattgggatt gactaaatcc tagaaaacta gatgaaaata aaaaattatg gtacaatagc
    28741 ttataatatt gtagccgatg gagaaagaca tgaatcttaa acgtgaacaa gaatttgtta
    28801 gtcagtatca ttttgatgca cgtaattttg aatgggaaaa tgaaaatgga gctcctgaaa
    28861 ccaaggtgga tgtgaatttc caattgctcc aacatgacca agaaaatcaa gtgacttcct
    28921 tgattgtcat tttgagcttt atgattgtat ttgataagtt tgtcattagt ggaacaatct
    28981 cacaagtaaa ccatatcgat ggccgtattg tcaatgaacc aagtgaattg aaccaagaag
    29041 aggtggaaac cttggctcgt ccatgtttga acatgctcaa tcgtttgact tacgaagtga
    29101 ctgaaattgc attagactta ccaggaatta atttggagtt ctaatatgaa attagctgtt
    29161 ttcacagatt cctctgctta tctcagtgaa gagaccttgc aaagagaaga cttgtttgtc
    29221 ttggatattc ctgtcaatat tgatggtgag gaatatgtcg aaggcatcaa tctgtctgct
    29281 gaggaatttt accaaaaaat ggctcaggct tctgaattgc ctaagaccag tcaaccaagt
    29341 attgccaagt tagatgagat cttaacttcg ctcaaagaac aaggctatac acatgccttg
    29401 gggcttttcc tatcttctgg aatttcaggt ttttaccaaa atatccagta tatggtcgat
    29461 gactatgagg gcttaaccat tgctttccca gacactttga ttacaagtgc tcccctaggc
    29521 atcatggttg aaagcgtctt taattggcgt gatcagggcg atgattttgc cagcattcag
    29581 gataagctag ccattcaaat cagccgtacg tcagccttta tcatggtaga tgacttggat
    29641 catttggtaa aaggtggacg cctttcaaat ggggctgcca ttttgggcaa tttgcttagc
    29701 attaagccaa tcctttattt taacgatcaa ggtgtgattg aagtttacga aaaagttcgt
    29761 actgaaaaga aggccaccaa gcgcttaatt gaaattatca aggaaacaac ggcttcaggt
    29821 caataccggg tcattgtcat tcatgggaat gctcctgaaa aggctgaaga attgcgtcag
    29881 cacttgcttg attttggctt gggttcggat gtttcacttg ctacatttgg tagtgtcatt
    29941 ggaacgcacc taggagcagg aagtattgct ctgggttata ttccagtgat ttagttggcg
    30001 cttctaggct agttaagatg ccttgtatct tagaaattga acacggacta cctgcctctt
    30061 gaaaaaagat gcctgtcttg cctttcgtgg aaagtcagtg ccattcccta tttttcagag
    30121 gcagctaagg tcctttgtat cttgataatt gaacacgcct ggaaccctgt gtgaaaaaga
    30181 tagttcttcc aagaagtaga cacttcttga ttggaattcc tattttcact ttgtgttctt
    30241 acggactttg tatcttagac aggagtagag atgagtattc gagtaattat tgccggtttt
    30301 aagggaaaga tgggccaggc tgcttgtcag atggtattga ctgatccaga cttggacttg
    30361 gtggcagttt tggatccttt tgagtctgag tcagaatggc agggtattcc tgttttcaag
    30421 gataaggctg atttagctgg ttttgaagcg gatgtctggg tagattttac tactccagct
    30481 gttgcctacg aaaatacacg ttttgctctt gaaaatggct ttgctccagt agttggaacg
    30541 actggtttca cgagtgaaga aattgcagag ctaaaagaat tttctcgtgc ccaagacttg
    30601 ggtggcctga ttgcccctaa ctttgccttg ggtgctgtct tactcatgca atttgcgacg
    30661 caggctgcca aatatttccc aaatgtggag attattgagc tccatcatga caagaaaaag
    30721 gatgctccga gtggaacagc cattaaaaca gctgagttga tggcagaggt tcgagagtcc
    30781 attcagcaag gcgcagcaga tgaggaagag ctgattgctg gtgctcgtgg tgctgacttt
    30841 gatgatatgc gcatccactc agttcgtttg ccaggcttgg tagctcatca ggaagtcatc
    30901 tttggcaatc agggagaagg gttgaccctc cgtcatgact cctatgatcg catctccttc
    30961 atgacaggag tcaatttggg aattaaagaa gttgtcaagc gtcatgagct tgtctatgga
    31021 ttagaacact tattatgaga ttaacgcaaa tgccttctga atttcagaag gctttaccag
    31081 tattagaaaa aattaaagaa gcaggctttg aggcttattt tgttgggggc tctgttcgag
    31141 atgcccttct ccatagccct atccacgatg tggatattgc gacgtcttct tatccagaag
    31201 agaccaagca gatttttccg cgaacagccg atatcggaat cgagcatgga accgtcttgg
    31261 tcttagatgg ggatgaggag tatgaggtaa caacctttcg gacagaggat gtctatgtgg
    31321 actatcgcag acccagtgcg gtttcctttg tacgatcgct agaagaagac ctcaaacgcc
    31381 gtgatttcac agtcaacgcc tttgccttgg atgagacagg agaaatcgtt gacttgttcc
    31441 atggtttaga agatttggaa aagcaagtct tgcgagcagt tggagtggct agtgagcgtt
    31501 tcaacgaaga tgctttacgg attatgcgtg gtttccgttt tcaggctagt cttggttttg
    31561 cacttgagcc agaaacattt aaagctatga agaccttgac gccgcttttg gagaaaattt
    31621 ctgtagagcg taccttcgtc gagtttgata aactcttgct ggctccattt tggagaaggg
    31681 gcttggcttc catgattgag agtcaagctt atgactatct ccctgatatg gcatctagcc
    31741 aggacaagct caacagactg tttgatttgg agactgattt tacttttgaa tcctctgaac
    31801 aagcctgggc ggctttacta tgggctttgg agattgaaaa tgcgcagtca tttttgaaat
    31861 cttggaagac ctcacgccag tttgccaagc aagttcagga tttgctgatt attttggctc
    31921 tgcgtgaaaa tggagaattg agtaagcgag attgttatcg ctttgacata gatttgcttt
    31981 tacaggctga aaatcttcgt caagctcaag gaaaagaagt caacccacaa gccatcacag
    32041 aaaaatacca aagcttgact atccatgaca agaaagagat tcagattaat ggcgatattt
    32101 tgatcaagga atatggctat cagccaggcc cagacttggg agagatttta acagagattg
    32161 agtttgccat tgtcgatgga gaattggaga ataatcgtga agccatccat gcttacctga
    32221 gggagaaaaa atgagtgatt ttatcgttga aaaactaagt aaatccgttg gtgacaagac
    32281 cgtttttagg gatatttcct ttattatcca tgacttagac agaattggtt taatcggtgt
    32341 caatgggact ggcaagacca cccttttgga cgtcctttct ggtgtttctg gatttgatgg
    32401 ggatgtcagt cctttttcag ctaaaaatga ttaccagatt ggttacttga ctcaggatcc
    32461 tgattttgat gatagaaaga cagttttgga tacggttcta tctagtgaac tcaaggaaat
    32521 ccagctcatt cgtgagtatg aattgattat gctcgactat agtgaggaca agcaggcgcg
    32581 tttggaacgt gtcatggcag agatggactc tctccaagct tgggaaatcg aaagtcaggt
    32641 caagaccgtt cttagcaaat tgggcattca agacttatct actcctgttg gggaattgtc
    32701 aggtggtctg agaagacggg tacagttggc acaagtctta cttggcaacc acgacctctt
    32761 gcttttggat gagccgacca accatctgga tattgcgatt attgagtggc tgaccctctt
    32821 tttgaaaaat tctaagaaga ccgtcctttt tatcactcac gatcgttatt tcttagacgc
    32881 tttgtcaaca cggattttcg agttggatcg tgcaggcttg accgagtacc agggcaatta
    32941 ccaggactat gttcgcctaa aggcggaaca ggatgagcgc gacgcggctc ttcttcacaa
    33001 aaaagaacaa ctctacaaac aagaactggc ctggatgcgc agacaaccgc aggcgcgtgc
    33061 gaccaagcag caggcccgta tcaatcgatt ccatgatctg aaaaaggaag tttcaggcag
    33121 tagtgctgag acagacttga ccatgaactt tgaaaccagt cggattggga agaaagtcat
    33181 cgagtttcag gctgtttcct ttgcctatga aaacaagcct attttgcaag attttaatct
    33241 cttggtgcag gccaaagacc gtatcggaat cgttggggac aatggtgttg gaaaatcaac
    33301 cctgctcaac ttgattgcag gaagtcttga gccaactaaa ggacaagttg tgattgggga
    33361 aactgttcgc atcgcctatt tctctcagca aattgagggt ttggatgaaa gcaagagagt
    33421 tatcaattac ctgcaggaag tggcagaaga ggtcaagacc agtggcggtt ctacgacttc
    33481 gattgcagag ttgctggagc agttcctttt cccacgttcg acgcatggaa ccttgattga
    33541 gaaattgtca gggggtgaga aaaaacgtct ttatctcctc aaactgcttt tggaaaaacc
    33601 aaatgttctt cttttagacg agccaaccaa tgacctagat attgcaactt tgacagtctt
    33661 agagaatttc ttgcaaggtt ttgcaggtcc cgttttaaca gtcagtcacg accgctattt
    33721 cttggataag gtagcgacca agattctcgc ttttgaggat agcaagattc gtcctttctt
    33781 tggtcattac accgactatc ttgatgaaaa agcttttgaa acagatatgg ccaatcaagt
    33841 gcaaaaggtc gaaaaggaaa aagtggtcaa ggttcgagaa gacaagaaac gtatgaccta
    33901 ccaagaaaag caggagtggg caagtattga aggtgatatt gaaaccttgg aaaaacgtat
    33961 cgctgctatt gaagaggaaa tgcaggctaa cggctctgac tttggtaagc tggctactct
    34021 ccaaaaagaa ttggatgaga aaaatgaagc actccttgaa aaatacgaac gctatgagta
    34081 tctcagtgaa tttgatagtt aagactattc gaaaatcaaa gtgcaaacta tgtcggcttc
    34141 acattgccga ctcaagtaca gcctgtgacc ggcttcctaa tttgcacttt gatttttatt
    34201 gagtataaaa gaatagaaaa atcccgtctc atgaaaggat ttctctattc ttttttggtt
    34261 tcttgatgaa agatattttg ccaggtttcg tggcgacgcc agatactggt atggatgata
    34321 ccatctaact catagcagat gagtttggtt ttttgactga tggaagtaat ttgaatgtcc
    34381 ttgatagcag aatttaactc ttttttggtc ttataagcct ctttatccat ctgctctcca
    34441 tcttggcgaa tatagacaaa atcatcagtc aagagttctt ctagttggtt tccttggtca
    34501 atcaattgtt cacgcataag caatttttta tagacattgt ctaaaatttc atcctcagag
    34561 ataggtgctg gttcgatatg gacatcggta tcaaagacgc caaaacgctc ctccagcata
    34621 gactcgacct gatccgcgat ttcatggctt tcaaaaacag acaagtcagg attcatctct
    34681 agtgtaatat ccaggtagat gttgctaccg taggtgcgac ctctttgcga tttgaccttg
    34741 ctgattttgg gaatttccat gatagccttt tggtagtcct cgagcaggcg gtcgtcaaag
    34801 ccatctgaaa gactaaagga agactcgatg aagatatcat aggcagtctt caagataaag
    34861 aaagtgatga tgatagcaac cagtttatcc acaatcggat aattgaaact actagctagg
    34921 atggcaatgg cggttccaag tgaggtaaca gcgtcagaaa gattgtcctt agcagctgcc
    34981 ttcagcgcct tggagttgga tttcttactg aggcgagtat tgtagagata gaccacaaac
    35041 ataatcgctg cagaaatgat tcctagagtt gcaccaagag gatcaatgac cgtttcttcc
    35101 cgactgagaa tcttttgaat ggtatctctt agaacatcga aaccgacata gaacatgatg
    35161 atagaagtga tcaagcttgc caaatcttca atcttccaat gaccaaaacg gtggtcacgg
    35221 tctgcaggct ggcgcgccat ccgaatcccg attaagaggg ccacatttcc aatgatgtcc
    35281 gatacgttat taaaaccatc ggccaccaaa ctggatgaat gaaggagatg accagctgct
    35341 aatttggctg cagacaagat caaataggtc gaaatactga taatggctcc acgctcagct
    35401 aacttgagat ttgagataga ttgcttcatt caacttcctt tctagtcaca tagcattcta
    35461 ccattatact ggttttcaag gaaaaattca aataaggcag tttttactct ttgaaaactc
    35521 cccaaaattt ggtataatgg tactactcaa gggagtagct ggcagaaacc tgtgatagtg
    35581 tcgtcattcc gaattttatg ctgaaaagta tgctttccgg ccctatctta aacagcgaga
    35641 cttgttatga ttaacaggtc tctttttgtt tgtcgtgaaa agatatgaca gaaagagagt
    35701 ctgttttgca cacaatgtca aggaggagac acatgtcaaa agaacaaaaa cgccaagcgt
    35761 tttatactca gagccctgaa gaggtcttgc aggctgtgga tgcgaccgag caaggtttgt
    35821 catcaagtga ggcggaaaag cgccttgctg aatttgggca caatgaactc gaagaaggcg
    35881 agaaacgatc aatcttggtc aaattcatcg agcaatttaa ggatttgatg attatcatcc
    35941 tagttgcggc agcaatcttg tcagtcgtga cttctggtgg ggaagatatc gcagatgcca
    36001 ttatcatcct agctgtggtt atcatcaacg ctgcctttgg tgtttaccaa gaaggaaaag
    36061 ctgaagaagc tattgaagcc ctcaaatcca tgtctagtcc agttgcccgc gttcttcgtg
    36121 atggacacat ggcagagatt gactctaaag aattggtacc aggcgatatc gttgcccttg
    36181 aagcaggtga cgtggtacca gcggacctac gtttgataga agccaactct cttaaaattg
    36241 aagaagcagc cttgacaggt gaatctgtac cagtcgaaaa agacttgtca gtcgagcttg
    36301 cgacagatgc tggtattggt gaccgtgtca acatggcctt ccaaaactca aacgtaacct
    36361 atggtcgtgg gatgggtgtt gttgtcaata caggtatgta cactgaagtt ggtcatattg
    36421 ctggtatgct tcaagatgcg gatgagactg atacaccact caaacaaaat ttgaacaacc
    36481 tttctaaggt cttgacctat gctatcttgg tcattgccct tgttactttt gtagtgggtg
    36541 tcttcattca agggaaaaat ccacttggtg agttgttgac ttctgttgcc cttgccgttg
    36601 cagccattcc agaaggactt cctgctatcg ttaccatcgt tctttctctt ggtactcaag
    36661 ttttggccaa acgacattcc atcgttcgta agttgccagc agttgaaaca cttggttcaa
    36721 ctgaaatcat cgcttctgat aagactggta cgctgactat gaacaagatg acagtcgaaa
    36781 aagtcttcta cgatgcggtt ctacatgact cagctgatga tattgaacta ggtcttgaaa
    36841 tgccactact tcgttcagtt gtcttggcca atgatacgaa aatcgatgtg gaaggtaact
    36901 tgattggtga cccaaccgaa acagccttta tccaatatgc cttggacaag ggctatgatg
    36961 tcaaaggttt cttagagaaa tatcctcgtg tagctgaatt gccatttgac tctgaccgta
    37021 agctcatgtc aacagttcac ccattgccag atggtcgttt ccttgtagca gtcaagggtg
    37081 cgccagacca actcttaaaa cgttgtcttc ttcgtgataa ggctggggat attgctccga
    37141 ttgatgagaa ggttacaaat ctcattcata caaacaattc tgaaatggct catcaagcct
    37201 tgcgtgtcct tgcaggtgct tataagatta tcgatagtat tccagaaaat ctcacttctg
    37261 aagagcttga aaatgattta atttttactg gtttgattgg gatgattgac cctgaacgtc
    37321 ctgaagccgc tgaggctgtt cgtgtggcta aggaagcggg aatccgtcca attatgatta
    37381 caggtgacca ccaagacaca gcggaagcca ttgccaaacg tttgggaatc attgacgcaa
    37441 acgatacaga aggtcacgtt ttaactggtg ctgaactcaa tgaactgtca gatgaagaat
    37501 ttgaaaaagt cgttggtcaa tactctgttt atgcccgtgt gtctccagaa cacaaggttc
    37561 gtatcgtcaa ggcttggcaa aaacaaggta aagtcgttgc catgacaggt gacggtgtca
    37621 atgacgcgcc agctctgaaa acagccgata tcggtatcgg tatgggaatc actggtacag
    37681 aggtttctaa gggggcttct gatatgattc ttgcagatga taactttgcg actattatcg
    37741 tcgcagtgga agaaggacgt aaggtcttct caaacattca aaagactatt cagtacctac
    37801 tttctgctaa tactgctgaa gtattaacca tcttcctatc aaccttgttt ggttgggatg
    37861 tcttacagcc ggttcatctt ttgtggatta acttggtaac ggataccttc ccagctatcg
    37921 ctcttggtgt tgaacctgcg gaacctggtg tcatgaatca taaaccacgt ggacgcaagg
    37981 caagcttctt ctcaggtggt gttttgagtt ctatcattta tcaaggtgta ctccaagcag
    38041 ctcttgttat gagtgtttat ggccttgcga ttgcttaccc agttcatgtg ggtgacaatc
    38101 atgctattca tgcagatgcc ctaacgatgg cctttgcaac ccttggtttg attcagctct
    38161 tccatgccta caatgtcaag tctgtctacc aatccatctt gacagttggc ccattcaagt
    38221 ctaagacctt taactggtcc atcttggtat cctttatcct tctcatggca acaatcgttg
    38281 tagaaccgct tgaaggaatc ttccacgtaa ccaaactaga cttgtcacaa tggggaattg
    38341 ttatggctgg aagcttctca atgattatca tcgtcgaaat cgttaagttt attcaacgca
    38401 aactcggttt tgacaagaat gcgatttaag ggaggtttcg gatgtcagca tatcaattac
    38461 cgaccgtatg gcaggatgaa gctagtaatc aaggagcttt tacggggcta aacagaccaa
    38521 cagcaggtgc ccgtttcgaa caaaacttgc caaaaggaga acaagctttt cagctttatt
    38581 cactgggaac accaaatggt gtgaaggtta ctatcttatt ggaagaatta ctagaagctg
    38641 gttttaagga agcggcttac gacttgtata agattgctat catggatggg gatcaattcg
    38701 gctcagactt tgtgaagctc aatccaaatt ccaagattcc agccttattg gaccagtcag
    38761 gtactgaaaa cgtaagagtc tttgagtctg ctcatattct tctttacctt gctgagaaat
    38821 ttggagcctt tttaccaagt aatcctgtgg aaaaggtaga agttttgaat tggctattct
    38881 ggcaagcagg tgcagcacct tttctaggtg ggggatttgg acatttcttc aattatgctc
    38941 ctgaaaaatt ggaatatcct attaaccgtt ttacgatgga agtgaaacgc cagttggatt
    39001 tattggataa ggaattggct cagaaacctt atattgcagg caatgactat acgattgcag
    39061 atattgctat ctggtcttgg tatggacagt tagttcaagg aaatctttac caaggttctg
    39121 caaaattctt ggatgcctca agttatcaaa atctagtaaa atgggcagaa aaaattgcca
    39181 atcgtccagc tgttaagcgt ggcttggaag taacttatac agaaattaaa tagcaaaaaa
    39241 gtcatcttcg gatggctttt tgctacagtt gagggaaagg gtttgcagtt atcggctttt
    39301 gtgctataat tgctataata tagtaaaaag caagaggagt gtgaggaagt ggaaaagaaa
    39361 attgtgaagg atatcttatt tttatctcaa gtgtctcatc cggcaagtca ggaggacctt
    39421 tatcttgcca gagatttgca ggatacactc ttagcaaatc gtgatacctg tgttggtcta
    39481 gctgccaata tgattgggat gcagaagcgc gtgattatct ttaatcttgg cttggttccc
    39541 gtggtcatgt ttaacccagt gcttctgtcc tttgaaggat cctatgaggc agaagaaggc
    39601 tgtttgtcct tggtaggtgt gagatcaact aagcgttatg aaaccataag gcttgcctat
    39661 cgtgacagca agtggcagga acagaccatt accttgacag gcttcccagc tcagatttgc
    39721 cagcatgagc tggatcactt ggaaggacga atcatttagg aggaaagcaa atgaaacgaa
    39781 tagtctttga acttattttt atcgcaacga cctggtatat ctttttaccg ccccttaacc
    39841 tgaccagctg ggaatttctc ttcttcctct gtgggcattt gttagttgtg gcaatcttat
    39901 ttggctttgg caaggggata aaccttgtca aaacggttca tgtgcgccac ggtaaggcgg
    39961 aagctgcctt aaatcttgag ggtttcaaaa tcaatcggtt agggaaaatt ctgttagctt
    40021 cgattggagg aattcttctc ttggcagctt tggtttcctt ggtaacttct agcatgtttc
    40081 aggctaaaaa ttatgccaat gtagtcacgg ttacggaaaa agactttact gaatttccta
    40141 agagtgacac cagtaaggtt cctatcctag atagaagtac tgctgaaaaa attggagacc
    40201 gctacttggg ttccctaacc gataaggtgt cgcaatacgt agcggcagat acctataccc
    40261 aattgacaat tgatgggaaa ccttatcggg tcacaccact agaatatgca gaccctatca
    40321 aatggtttaa caatcaagcc aagggaatcg gtgagtatat caaggtggac atggtaactg
    40381 gaaatgcgga tttggtggac ttgaagacac caatcaagta ttcagactcg gagtatttta
    40441 accgtgatgt caaacgtcac ctgcgcttga agtacccgac caaaatcttt aaaactccat
    40501 cttttgaggt ggacgatgag ggcaatcctt tctatgtagc aacggtttac caaaagcaat
    40561 ttggacttgc tgttcctcgt cctgcttcag tcattatctt ggatgctaca aatggagaaa
    40621 ccaaggaata cagcttatca gatgttccag aatgggtgga caggatctat ccagcagagg
    40681 aaaccattga gcaaatcaac tacaacggca agtacaagga cggtttcttg aatgccatga
    40741 tttccaagaa aaacgtgacc cagacgacca atggctataa ttacttgtct atcggtaatg
    40801 acatctatct ctacacaggt gtgacgtcgg ctaatgcgga tgagagtaat cttggtttca
    40861 tccttgaaaa tatgcgaaca ggagaaatta ctaagtatag cttggcttct gcgacagaag
    40921 aatcagcccg tgaatcagca gaaggtgctg ttcaggagaa atcctacaaa gcaaccttcc
    40981 caatcctcat caacctcaat gacaagcctc tctacatcat gggcttaaag gacaatgctg
    41041 gcttggtcaa agagtacgcc ctggtagacg cagtcgagta ccaaaatgtt atcgttgcta
    41101 ctacagtgga agagatgctc agcaagtatg ccaataaaaa cgaccttgaa attgacaatg
    41161 caacgacaga aagcatcaag ggagtagtag cagacctcaa atcagctgtt atcaagggag
    41221 acactgtcta cttctttaaa gttgatggca agatatacaa ggtaaaggct tcagtatccg
    41281 atgaccttcc ttaccttgaa aatggtaaaa ccttcgaagg tcaagtagga aaagacaatt
    41341 atctcaagac ctttaaagta caataatact cttcgaaaat ctctagctct atctgcaacc
    41401 tcaaaacagt gttttgagca gcctgcggct agtttcctag tttgctcttt gattttcatt
    41461 gagtataaaa aaggtttatt taataaatat atgttataat aaggtaaatt aagcctaatg
    41521 gaggacaaag aaatgggttt ttatttgatg gttgcttcaa tgctactcgg actgctcgct
    41581 ttgaagatag gtttttctca gttcaaggag aaaaaagata aattcttatc tatcttaaca
    41641 agtttagctg gcacagccct tgttctcgtg gctgtctggt taggatggcc caaataaata
    41701 gaaaaacctc ggtcaaaccg aggtttttca aatgaatttc ttggttgtgg ctaaaaaata
    41761 tgctacacta tcaatatgaa aattttaatc ccaacagcaa aagaaatgaa cacagacttg
    41821 ccaagtatcg aggcaattcc tttaaaacca gaaagtcaga ccgtgcttga tgccttggct
    41881 ctctattctg ccagtcaatt ggagagtttc tacaaggtat cagctgagaa agcggcggaa
    41941 gaatttcaaa atatccaagc tttgaaaagg caaactgctc aacactatcc agccttgaaa
    42001 ctttttgatg ggcttatgta ccgcaacatt aagagagata agctgaccga ggcggaacaa
    42061 gattatcttg aaaatcatgt cttcattacc tcggctttgt acggtgttgt tccagccttg
    42121 tcacccatgg ctcctcaccg tttggatttt ttgatgaaat taaaagtcgc tggtaagact
    42181 ttgaagagcc attggaaggc agtctatgat gaagctctga agaaggaaga agtgattttc
    42241 tctctcttgt catcagagtt tgagactgta ttttctaagg aaatcagagc aaagatggtg
    42301 accttcaaat tcatggagga tagaggcggt cagctgaaga ttcactcaac tatctccaag
    42361 aaagcgcgcg gggcctttct aacagcttta atagaaaatc aagtacaaac tgtgggggaa
    42421 gcacgtcgct tgaactttgc tggatttgtt taccgagaag atttgtcaca accacaggga
    42481 ttggtttttg taaaggaagt atagaaatca gataagagaa aagtcagcac gattatgctg
    42541 acttttttga taacttataa agtattggac aaatgaatct catttgataa ggtgttaaga
    42601 tgattaacca aattcatgat tgacagatga tttcggcaaa taaacttctt ggtaatccct
    42661 gaaatataga aattagacac gatgatatcg taatctgtct gatttaaaat ctcaggactt
    42721 gtttttaatt catcccaaat atcgaaggta aagcggttat tacagtaata ggaaagcata
    42781 tcaacaaagg taagggatat agcatggtca aagttactga taatcaaaac cttgataggt
    42841 ggtcgatttt ctaacaactg agtagagagg ttttcagcat gggttaagat ggtgtacatc
    42901 aagtgttcca actgttcagg atggtcatgc tgtccaattg cctgacggta ttgagccagt
    42961 tcttgacgcg cacttcccat aaagtctggg aagtaacctt caaatttttt aatcgtcaat
    43021 gctttttgtt caaataagat tggggtagaa aagatttcct gtctttcaaa gaaagcagtg
    43081 ttgtgtaaat gccaaatcag ctcatcgtgg ttagtaaaag taatcttata ttgttttgat
    43141 aggcgttcta atatttgact aagtaattgg taagagtatc ttgcttgact gttatcttct
    43201 aaagagttga agaattcttg aggatctagg aaaatatcat tctgaagaaa agaaataaaa
    43261 atttgagcga ttgtatctgg agtcatttca agcccaaaat gtttagagaa ataagcaagt
    43321 gtctcctgga aatttggaat gctctttaaa agaggataat attctttgta aaagtggttg
    43381 gggaggtcaa tgaagtgacc atttttaacc ctgtggatac tgatagctat catcagtttg
    43441 tacattctat aaattgaaaa tcgcattgga taattcgtga ttttatagaa gaagtcagca
    43501 aactctgtta aatcttcctc aggaaggtca ggaaaaggcc aatctaggaa ataatagcgc
    43561 tcagaaaagt attgggcaaa aaagtaacga atatcgatct catttccacg tatctcggat
    43621 ggagtaaaag ataattcaat ttgaaactga gatgaaagaa cctttgtaat atttctgccc
    43681 agtcgataga ggttggcact actaaagtaa agattttcta ttgttcgata aataggtagc
    43741 ccctcattga agaacatata ctctagtaat tgaaaagatt gagaattagc aagaaaatat
    43801 tgataaatat cttctacact agtgttaact tctaaatcta tcatgattcc gttaacagaa
    43861 gattggatgt taatagatgg aaaggcaata cgtaattcat ttaaatcact ttttaagatt
    43921 cgttctgtac atcctaattt ttcggctagt tcatgtaatt tcatccaatt acgattctga
    43981 attagggttt ccattaagcg taattgtctt tgaacttttg tggataaaag gtttctcata
    44041 cgggtatttc ctccataatt cattatatct ttttttgtct aagtagtata aaaaaattag
    44101 agcaagaaaa ttgtcgttag taatcggaaa aattagaata atataagtgg cttttaagtg
    44161 caaaaacaga atatattaat tgttcagaaa atattgatta atgcctcaaa tagttgtaca
    44221 ttgtaaacta taaaatacta tctaggagtt taaaatgaaa cattcacata aaaaatcatt
    44281 tgactggtat agcatgcaac aacgttattc tattcgtaag tattactttg gtgcagttag
    44341 tgtcttgctc ggtaccgctt tggtattagg tgcagcagct agtgtccaaa cagtacaagc
    44401 ggaagaaaac aaacaagaaa ctaccaatag tatttctgtt ggtaggggag aagcagctac
    44461 taaaccagca gaggtttctg cgtctaataa agagaaaacc tatgcagctc caactgtagc
    44521 taatccagta gaaacgactc cagttaaaac tggagaagtt actaaaccag cagaaaaagt
    44581 tgaagaagca aaagacaaaa aagaggaagt aacgcatcaa gatgctattg acaagtcaaa
    44641 attgttaacg gctctttcgc gtgctaaaaa gttagaaagc aagttatata cagaagcaag
    44701 tgctgctaac ttgcaaacaa gtatccaagc tggtcaaagc ttgcttggga aagcagatgc
    44761 atctgaagct gaattatcag cagcagagtc atctattcaa tcatctatta ttggtctaga
    44821 acttcgttct aactctaaca aaggaactgt atcagaaact cctgtagcga agaaagctaa
    44881 tatagttgaa gcgaaggaag agactaatcc agctgcaaca actgatcgtt cagctgttga
    44941 tagtgctgtt ttgccaacta gcacagctgc caaagtagaa acaacttcag ctccagcatc
    45001 tattaatgaa atcttgaaac caggtttgag cctttctgat gctcgccaaa atccagctat
    45061 ccgtaaggaa gatgttgata gagggtatag tggttttaga gcggcgcctg ctccaacgaa
    45121 ccaaccagta actaatctag gaaataatac tgttttcact gatattagca gaggttctca
    45181 tactttccgt ggtaatggaa attcacgtcg tggaaacccg attcattttg atgtaacaac
    45241 aactagagtt agaaatagag tagatttctc aatcagatat tcaggaccag gtgagtttgt
    45301 taataacaac tttatcttag acaaaggaaa tggattcgga gaaccttctc gtgcaactgt
    45361 ttcaacacca aaattaagag accaagttaa aaacattagt aagggtggaa actttgtttc
    45421 tcattcaggc tacagtttag aagctgcagt agaaacaagc accaatcaaa caattaagtt
    45481 tagtttacct atagccaacc ctaatggtga tctgtctgtt cgattaagac ctgttacttt
    45541 taatgtaggt caaggggaat caggatctgc aactagtaat gatccatata gtaactctaa
    45601 ctattacttc agagaaaaac cactcctctt ggatgcaaat ccaaatggtg gtactaataa
    45661 taagactgtt tcagaagaca ttgacttcca aactgtctat cttccaacta gtaagttacc
    45721 agaaggtcaa actagattag ttcgagaagg tgaaaaagga caacgtcaaa tcatctataa
    45781 agttcatcaa ttgggtaacg aaacaatcct aggattgcca attagtaatt cagttattaa
    45841 agaagttaag ccacgtatta tgcaaattgg tgtggctaaa gatctaatcg atacagtaaa
    45901 accacgtgtt gatcaaaata aagtcggtga tacaaataac ctcactttct atcttgataa
    45961 cgatggaaac ggtgtttata ctgagggcgt agacgaactt gttcaaaaaa ttgctattaa
    46021 agatggtgct aaaggtgaaa aaggagaccg aggcgaacgc ggtctaactg gagctcaagg
    46081 agctaaaggt gaaaaaggag accgaggtga acgcggtcta actggagctc aaggagctaa
    46141 aggtgaaaaa ggagaccgag gtgaacgcgg tctaaccgga gctcaaggag ctaaaggtga
    46201 aaaaggaga
//
LOCUS       DAVBDR010000009        42370 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.009, whole genome shotgun sequence.
ACCESSION   DAVBDR010000009 DAVBDR010000000
VERSION     DAVBDR010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 42370)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42370)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42370
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.009"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            <1..128
                     /locus_tag="VQ540_000542"
     CDS             <1..128
                     /locus_tag="VQ540_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HET2544399.1"
                     /translation="FRSLENLEQAIVDYIDYYNNKRIKVKLKELSPVQYRTKSFG"
     gene            complement(176..2719)
                     /locus_tag="VQ540_000543"
     CDS             complement(176..2719)
                     /locus_tag="VQ540_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HET2544400.1"
                     /translation="MKSFLKTYRTYFISFIIPVVIMSGVYLSQGIYWNSDNSPLLGDG
                     FHQYVIFDVALRNILHGNSSLFYTFTSGLGLNFYALSSYYLGSFLAPLVYFFDLTNMP
                     DAVYLTTLLKFGLIGLSTFFSLNKLFQSIPQTLKLALSTSYALMSFTVSQLEIKTWLD
                     VFILIPLIITGLHLLITEKKLLLYFTSLSILFIQNYYFGYMTVLFLIFWYLCQISWDF
                     KTRKSSVLDFIVISFLAGMASLIMTLPTLFDLQTHGEKLTEVTKFQTESSWYLDLFAK
                     QFIGSFDTTKYGAIPMIFVGLFPFILTILFFTLKSIKFHVKLIYVIFFAFLIASFYIE
                     ALDLFWQGMHTPNMFLHRYAWIFSTLLIYTAAEVLKRLKELKVWNFLVSLFLVVAGFL
                     ATIYLKSHYSFLTDLNILLTLEFLVVYSLLLLAVIKKFISVNLFAILISLFILVEMSL
                     NASSQMDGIAKEWGFASRSAYSRDIPAMESFSTYIGNQFTRTEKLQTQTGNDSMKFNY
                     NGISQFSSVRNRSSSSTLDKLGFKSSGTNLNLRYANNSILADSLFGIQYNISDSPIDK
                     YGFKDIYQKDNLTLYENQYSLPIAVASQSVYNDVKFNEHTLDNQASFLNQLANVNFDY
                     FSPIPYEKTENTNDLISVTSSSNEDAAIQYQIEVPENSQVYLSFINLHFSNDKQKKVD
                     ILVNGEKKTFTTDNVFSFFNLGYTKEKKTFNINVSFPGNSQVSFESPTFYRLDTKTFT
                     EAIQKIKEQPVTVSTSKNKVFATYDVQQDTSIFFTIPYDKGWSAYQDGKKIEIKQAQT
                     GFMKVDIPKGKGTITLSFIPNGFITGAICSFTSLLLFGIYNHRRKSSKA"
     gene            complement(2781..4403)
                     /locus_tag="VQ540_000544"
     CDS             complement(2781..4403)
                     /locus_tag="VQ540_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET2544401.1"
                     /translation="MLTVSDVSLRFSDRKLFDDVNIKFTEGNTYGLIGANGAGKSTFL
                     KILAGDIEPTTGHISLGPDERLSVLRQNHFDYEDERAIDVVIMGNEKLYSIMKEKDAI
                     YMKEDFSDEDGVRAAELEGEFAELGGWEAESEASQLLQNLNIPEELHYQNMSELANGE
                     KVKVLLAKALFGKPDVLLLDEPTNGLDIQSITWLEDFLIDFDNTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWKESSELAAKLLADRNAKAEEKIKQLQEFVARFSANA
                     SKSRQATSRKKMLDKIELEEIVPSSRKYPFINFKAEREIGNDLLTVENLTVKIDGETI
                     LDNISFILRPDDKTALIGQNDIQTTALIRAIMGDIDYEGTVKWGVTTSQSYLPKDNSA
                     DFAGGESILDWLRQFASKEEDDNTFLRGFLGRMLFSGDEVNKPVNVLSGGEKVRVMLS
                     KLMLLKSNVLVLDDPTNHLDLESISSLNDGLKNFKESIIFASHDHEFIQTLANHIIVL
                     SKNGVIDRIDETYDEFLENAEVQAKVKELWKD"
     gene            4609..5634
                     /gene="trpS"
                     /locus_tag="VQ540_000545"
     CDS             4609..5634
                     /gene="trpS"
                     /locus_tag="VQ540_000545"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HET2544402.1"
                     /translation="MTKPIILTGDRPTGKLHIGHYVGSLKNRVLLQEEDKYDMFVFLA
                     DQQALTDHAKDPQTIVESIGNVALDYLAVGLDPNKSTIFIQSQIPELAELSMYYMNLV
                     SLARLERNPTVKTEISQKGFGESIPTGFLVYPIAQAADITAFKANYVPVGTDQKPMIE
                     QTREIVRSFNNAYNCDVLVEPEGIYPENERAGRLPGLDGNAKMSKSLNNGIYLADDAD
                     TLRKKVMSMYTDPDHIRVEDPGKIEGNMVFHYLDVFGRPEDAQEIADMKERYQRGGLG
                     DVKTKRYLLEILERELGPIRERRIEFAKDMGEVYNMIQKGSERAREVAGQTLSEVKGA
                     MGLHYFN"
     gene            5787..7265
                     /gene="guaB"
                     /locus_tag="VQ540_000546"
     CDS             5787..7265
                     /gene="guaB"
                     /locus_tag="VQ540_000546"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HET2544403.1"
                     /translation="MSNWDTKFLKKGFTFDDVLLIPAESHVLPNDADLTTKLADNLTL
                     NIPIITAAMDTVTESQMAIAIARAGGLGVIHKNMSIAQQADEVRKVKRSENGVIIDPF
                     FLTPEHTIAEADELMGRYRISGVPVVETLENRKLVGILTNRDLRFISDYNQPISNHMT
                     SENLVTAPVGTDLATAESILQEHRIEKLPLVDEEGSLSGLITIKDIEKVIEFPNAAKD
                     EFGRLLVAGAVGVTSDTFERAEALFEAGADAIVIDTAHGHSAGVLRKIAEIRAHFPDR
                     TLIAGNIATAEGARALYEAGVDVVKVGIGPGSICTTRVIAGVGVPQVTAIYDAAAVAR
                     EYGKTIIADGGIKYSGDIVKALAAGGNAVMLGSMFAGTDEAPGETEIFQGRKFKTYRG
                     MGSIAAMKKGSSDRYFQGSVNEANKLVPEGIEGRVAYKGAAADIVFQMIGGIRSGMGY
                     CGAANLKELHDNAQFIEMSGAGLKESHPHDVQITNEAPNYSM"
     gene            complement(7316..8413)
                     /gene="recF"
                     /locus_tag="VQ540_000547"
     CDS             complement(7316..8413)
                     /gene="recF"
                     /locus_tag="VQ540_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000266665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HET2544404.1"
                     /translation="MWLQHLSLKTFRNYKETKIDFNPKLNVFLGRNAQGKTNMLEAIY
                     FLALTRSHRTRTDKNLIHFDEEQLHLSGLVQKKTGSIPLEIELTQKGRVTKVNHLKQA
                     RLSDYVGHMNVVLFAPEDLQLIKGAPSIRRKFIDMELGQIKPIYLSDLTNYNHILKQR
                     NTYLKSAQKIDETFLSVLDDQLVDYGCRVMNHRLDFIKKLESFGRKKHFELSNQIEEL
                     SISYQSSVNITDKQNLSESFKIALEKSRSRDLFKKNTGVGPHRDDISFYINGMDASFG
                     SQGQHRSLVLSIKLAEIELMESITTESPILLLDDVMSELDNTRQLKLLETISQSIQTF
                     ITTTSLDHLQNLPENLSIFTIQDGKAAVNGN"
     gene            complement(8416..8784)
                     /gene="yaaA"
                     /locus_tag="VQ540_000548"
     CDS             complement(8416..8784)
                     /gene="yaaA"
                     /locus_tag="VQ540_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HET2544405.1"
                     /translation="MEYKLFEEFITLQALLKELGITHSGGAIKSFLSEHSVYFNRELE
                     SRRGKKLRIGDKIDIPDMNIDILLTQSTSEEQDEYQADKVEKERIAKLVKKMNKGVKK
                     DKSKPASSPKSQQAPRFPGR"
     gene            8943..10193
                     /locus_tag="VQ540_000549"
     CDS             8943..10193
                     /locus_tag="VQ540_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HET2544406.1"
                     /translation="MELVHGISTHFIQSKKFKTNKITVRFTAPLSLDTIAGHMLSASM
                     LETANQMYPTSQDLRRHLASLYGTDMSTNCFRRGQSHIIELTFTYVRDEFLSRKNVLT
                     SQILELVKETLFSPVVVDNGFDPALFEIEKKQLLASLAADMDDSFYFAHKELDKLFFH
                     DERLQLEYSYLRNRILAETPQSSYSCFQEFLANDRIDFFFLGDFNEVEIQNVLESFGF
                     KGRKGDVKVQYCQPYSNILQEGMVRKNVGQSILELGYHCPSKYGDEKHLPMIVMNGLL
                     GGFAHSKLFTNVRENAGLAYTISSQLDLFSGFLRMYAGIDRENRNQARKMMNNQLLDL
                     KKGYFTELELEQTKEMIRRSLLLSQDNQSSLIERAYQNALLGKSSADFKSWIAKLEQV
                     DKDAICRAANNVKLQAIYFMEGIE"
     gene            10190..11473
                     /locus_tag="VQ540_000550"
     CDS             10190..11473
                     /locus_tag="VQ540_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HET2544407.1"
                     /translation="MTKVVFEEKYYPAVKEMVYRTRLANGLTVALLPKKEFKEVYGSV
                     TVQFGSVDTLVTEVDGDVKQYPAGIAHFLEHKLFEREDSSDLMSAFTSLGADSNAFTS
                     FTKTNYLFSATDYFLENLDLLDELITSAHFTEASILTEQDIIQQEREMYQDDPDSCLF
                     FSTLANLYPGTPLATDIVGSEESISQINLTNLQENFTKFYKPVNMSLFLVGNFDVERV
                     QDYFESKELKDSDFQEVAREKLFLQPVKLTDSMRMEVSSPKLAIGVRGKREVSEADCY
                     RHHILLKLLFAMMFGWTSDRFQKCYESGKIDASLSLEVEITSRFHFVMLTMDTKEPVA
                     LSHQFRKAIRNFTKDLDITEEHLDIIKREMFGEFFSSMNSLEFIATQYDAFENGETIF
                     DLPKILQEITLEDVLDAGHHLIDDGDIVDFTIFPS"
     gene            11515..12336
                     /locus_tag="VQ540_000551"
     CDS             11515..12336
                     /locus_tag="VQ540_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET2544408.1"
                     /translation="MRKKTIGEVLRLARINQGLSLDELQKKTEIQLDMLEAMEADDFD
                     QLPSPFYTRSFLKKYAWAVELDDQIVLDAYDSGSMITYEEVDVDEDELTGRRRSSKKK
                     KKKTSFLPLFYFILFALSILIFVTYYVWNYIQTQPEEPSLSNYSVVQSTSSTSSVPHS
                     SSSSSSSIESAISVSGEGNHVEIAYKTSKETVKLQLAVSDVTSWVSVSESELEGGVTL
                     SPKKKSAEATVATKSPVTITLGVVKGVDLTVDNQTVDLSKLTAQTGQITVTFTKN"
     gene            12347..12892
                     /gene="pgsA"
                     /locus_tag="VQ540_000552"
     CDS             12347..12892
                     /gene="pgsA"
                     /locus_tag="VQ540_000552"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HET2544409.1"
                     /translation="MKKEQIPNLLTIGRILFIPIFIFILTIGNSIESHIVAAIIFAVA
                     SITDYLDGYLARKWNVVSNFGKFADPMADKLLVMSAFIMLIELGMAPAWIVAVIICRE
                     LAVTGLRLLLVETGGTILAAAMPGKIKTFSQMFAIIFLLLHWTLLGQVLLYVALFFTI
                     YSGYDYFKGSAYVFKGTFGSK"
     gene            12889..13716
                     /locus_tag="VQ540_000553"
     CDS             12889..13716
                     /locus_tag="VQ540_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HET2544410.1"
                     /translation="MKSIIDVKNLSFRYKENQNYYDVKDITFHVKRGEWLSIVGHNGS
                     GKSTTVRLIDGLLEAESGEIVIDGQRLTEENVWNIRRQIGMVFQNPDNQFVGATVEDD
                     VAFGLENQGLSRQEMKKRVEEALALVGMLDFKKREPARLSGGQKQRVAIAGVVALRPA
                     ILILDEATSMLDPEGRRELIGTVKGIRKDYDMTVISITHDLEEVAMSDRVLVMKKGEI
                     ESTSSPRELFSRNDLDQIGLDDPFANQLKKSLSQNGYDLPENYLTESELEDKLWELL"
     gene            13701..14540
                     /locus_tag="VQ540_000554"
     CDS             13701..14540
                     /locus_tag="VQ540_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000510406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HET2544411.1"
                     /translation="MGIALENVNFTYQEGTPLASAALSDVSLTIEDGSYTALIGHTGS
                     GKSTILQLLNGLLVPNQGSVRVFDTLITSTSKNKDIRQIRKQVGLVFQFAENQIFEET
                     VLKDVAFGPQNFGVSEEDAVKTAREKLALVGIDESLFDRSPFELSGGQMRRVAIAGIL
                     AMEPAILVLDEPTAGLDPLGRKELMTLFKKLHQSGMTIVLVTHLMDDVAEYANQVYVM
                     EKGRLVKGGKPSDVFQDVVFMEEVQLGVPKITAFCKRLADRGVSFKRLPIKIEEFKES
                     LNG"
     gene            14533..15327
                     /locus_tag="VQ540_000555"
     CDS             14533..15327
                     /locus_tag="VQ540_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000377903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HET2544412.1"
                     /translation="MDSMILGRYIPGDSIVHRLDPRSKLLAMMLLILIVFWANNPLTN
                     LILFIATGIFIALSGVSLSFFIQGLKSMFFLIAFTTIFQLFFISNGNVLFEFSFVRIT
                     DYALQQAGIIFCRFVLIIFFSTLLTLTTMPLSLASAVEALLAPLKRVKVPVHEIGLML
                     SMSLRFVPTLMDDTTRIMNAQKARGVDFGEGSIVQKVKAMIPILIPLFATSLKRADSL
                     AIAMEARGYQGGKGRSQYRQLKWTLKDTLTILVILVLGCCLFFLKS"
     gene            15386..16204
                     /gene="mreC"
                     /locus_tag="VQ540_000556"
     CDS             15386..16204
                     /gene="mreC"
                     /locus_tag="VQ540_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HET2544413.1"
                     /translation="MNRFKKSKYVIIVFVTVLLVSALLATTYSSTIVTKLGDGISLVD
                     RVVQKPFQWFDSVKSDLAHLTRTYNENESLKKQLYQLEVKSNEVESLKTENEQLRQLL
                     DMKSKLQATKTLAADVIMRSPVSWKQELTLDAGRSKGASENMLAIANGGLIGSVSKVE
                     ENSTIVNLLTNTENADKISVKIQHGSTTIYGIIIGYDKENDVLKVSQLNSNSDISAGD
                     KVTTGGLGNFNVADIPVGEVVATTHSTDYLTREVTVKLSADTHNVDVIELVGNS"
     gene            16204..16698
                     /gene="mreD"
                     /locus_tag="VQ540_000557"
     CDS             16204..16698
                     /gene="mreD"
                     /locus_tag="VQ540_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HET2544414.1"
                     /translation="MRQLKRVGVFLLLPFFVLIDAHISQLLGSFFPHVHLASHFLFLF
                     LLFETIEVSEYLYLVYCFVIGLVYDVYFFHLIGITTLLFILLGAFLHKLNSVILLNRW
                     TRMLAMIVLTFLFEMGSYLLAFMVGLTVDSMSIFIVYSLVPTMILNFLWITVFQFIFE
                     KYYL"
     gene            16792..17970
                     /locus_tag="VQ540_000558"
     CDS             16792..17970
                     /locus_tag="VQ540_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HET2544415.1"
                     /translation="MKKKILASLLLSTVMVSQVAVLTTAHAETTDDKIAAQDNKISNL
                     TAQQQEAQKQVDQIQEQVSAIQAEQSNLQAENDRLQAESKKLEGEITELSKNIVSRNQ
                     SLEKQARSAQTNGAVTSYINTIVNSKSITEAISRVAAMSEIVSANNKMLEQQKADKKA
                     ISEKQVANNDAINTVIANQQKLADDAQALTTKQAELKAAELSLAAEKATAEGEKASLL
                     EQKAAAEAEARAAAVAEAAYKEKRASQQQSVLASANTNLTAQVQAVSESAAAPVRAKV
                     RPTYSTNASSYPIGECTWGVKTLAPWAGDYWGNGAQWATSAAAAGFRTGSTPQVGAIA
                     CWNDGGYGHVAVVTAVESTTRIQVSESNYAGNRTIGNHRGWFNPTTTSEGFVTYIYAD
                     "
     gene            18194..18973
                     /gene="rpsB"
                     /locus_tag="VQ540_000559"
     CDS             18194..18973
                     /gene="rpsB"
                     /locus_tag="VQ540_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HET2544416.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIHVIDLQ
                     QTVKYADQAYDFMRDAAANDAVVLFVGTKKQAADAVAEEAVRSGQYFINHRWLGGTLT
                     NWGTIQKRIARLKEIKRMEEDGTFEVLPKKEVALLNKQRARLEKFLGGIEDMPRIPDV
                     MYVVDPHKEQIAVKEAKKLGIPVVAMVDTNTDPDDIDVIIPANDDAIRAVKLITAKLA
                     DAIIEGRQGEDAVAVEAEFAASETQADSIEEIVEVVEGDNA"
     gene            19052..20092
                     /locus_tag="VQ540_000560"
     CDS             19052..20092
                     /locus_tag="VQ540_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HET2544417.1"
                     /translation="MAEITAKLVKELREKSGAGVMDAKKALVETDGDIEKAIELLREK
                     GMAKAAKKADRVAAEGLTGVYVNGNVAAVIEVNAETDFVAKNAQFVELVNTTAKVIAE
                     GKPANNEEALALIMPSGETLEAAYVSATATIGEKISFRRFALIEKTDAQHFGAYQHNG
                     GRIGVISVVEGGDEALAKQLSMHIAAMKPTVLSYKELDEQFVKDELAQLNHVIDQDNE
                     SRAMVNKPALPHLKYGSKAQLTDDVIAQAEADIKAELAAEGKPEKIWDKIIPGKMDRF
                     MLDNTKVDQAYTLLAQVYIMDDSKTVEAYLESVNASVVEFARFEVGEGIEKAANDFEA
                     EVAATMAAALNN"
     gene            20339..20680
                     /gene="tnpB"
                     /locus_tag="VQ540_000561"
                     /pseudo
     CDS             20339..20680
                     /gene="tnpB"
                     /locus_tag="VQ540_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
     gene            complement(20816..21103)
                     /locus_tag="VQ540_000562"
                     /pseudo
     CDS             complement(20816..21103)
                     /locus_tag="VQ540_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            21094..21492
                     /locus_tag="VQ540_000563"
     CDS             21094..21492
                     /locus_tag="VQ540_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2544418.1"
                     /translation="MKSPIPKAPLAHNFGSASIIAHTIHQKFNLKVPNYRQEEDWARM
                     GLPIIRKEISNWHIKTSQYYLEPLYNLLRERLLTQPLLHADETSYRVLESDSQLTYYW
                     TFLSGKAEKQGITLYHHVLIDLFISYFNPL"
     gene            complement(21689..22609)
                     /gene="cysK"
                     /locus_tag="VQ540_000564"
     CDS             complement(21689..22609)
                     /gene="cysK"
                     /locus_tag="VQ540_000564"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HET2544419.1"
                     /translation="MSIYNNITELIGQTPIVKLNNIVPEGAADVYIKLEAFNPGSSVK
                     DRIALSMIEKAEQDGILKLGSTIVEATSGNTGIGLSWVGAAKGYKVVIVMPETMSVER
                     RKIIQAYGAELVLTPGSEGMKGAIAKAQEIAAERDGFLPLQFDNPANPEVHERTTGAE
                     ILAAFGKDGLDAFVAGVGTGGTISGVSHALKSENSNIQVFAVEADESAILSGEKPGPH
                     KIQGISAGFIPDTLDTKAYDGIVRVTSDDALALGREIGGKEGFLVGISSAAAIYGAIE
                     VAKKLGTGKKVLALAPDNGERYLSTALYEL"
     gene            complement(22894..23529)
                     /locus_tag="VQ540_000565"
     CDS             complement(22894..23529)
                     /locus_tag="VQ540_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HET2544420.1"
                     /translation="MEFRTIKEDGQVQEEIKKSRFICHAKRVYSEEEARDFITAIKKE
                     HYKATHNCSAFIIGERSEIKRTSDDGEPSGTAGVPMLGVLENHNLTNVCVVVTRYFGG
                     IKLGAGGLIRAYAGSVALAVKEIGIIEIKEQAGIAIQMSYAQYQEYSNFLKEHDLMEL
                     DTNFTDQVDTMIYVDKEEKETIKAALVEFFNGKVTLTDQGLREVEVSVNLV"
     gene            23585..24883
                     /locus_tag="VQ540_000566"
     CDS             23585..24883
                     /locus_tag="VQ540_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HET2544421.1"
                     /translation="MKVNLDYLGRLFTENELTEEERQLAEKLPAMRKEKGKLFCQRCN
                     STILEEWYLPIGAYYCRECLLMKRVRSDQTLYYFPQEDFPKQDVLKWRGQLTPFQEKV
                     SEGLLQAVDKQKPTLVHAVTGAGKTEMIYQVVAKVINAGGAVCLASPRIDVCLELYKR
                     LQQDFSCGIALLHGESEPYFRTPLVVATTHQLLKFYQAFDLLIVDEVDAFPYVDNPTL
                     YHAVKNSVKENGLRIFLTATSTNELDKKVRLGELKRLSLPRRFHGNPLIIPKPIWLSD
                     FNRYLDKNRLSPKLKSYIEKQRKTAYPLLIFASEIKKGEQLEEILQEQFPNEKIGFVS
                     SVTEDRLEQVQAFRDGELTILISTTILERGVTFPCVDVFVIEANHRLFTKSSLIQIGG
                     RVGRSMDRPTGDLLFFHDGLNASIKKAIKEIQMMNKEAGL"
     gene            24880..25542
                     /locus_tag="VQ540_000567"
     CDS             24880..25542
                     /locus_tag="VQ540_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HET2544422.1"
                     /translation="MKCLLCGQTMKTVLTFSSLLLLRNDDSCLCSDCDSTFERIGEEN
                     CPNCMKTELSTKCQACQFWCKEGVEVSHRAIFTYNQAMKDFFSRYKFDGDFLLRKVFA
                     SFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREERASSS
                     KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSL
                     VR"
     gene            25622..26170
                     /gene="raiA"
                     /locus_tag="VQ540_000568"
     CDS             25622..26170
                     /gene="raiA"
                     /locus_tag="VQ540_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000599099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HET2544423.1"
                     /translation="MIKYSIRGENLEVTEAIRDYVVSKLEKIEKYFQPEQELDARINL
                     KVYREKTAKVEVTIPLGSITLRAEDVSQDMYGSIDLVTDKIERQIRKNKTKIERKNKN
                     KVATGQLFTDALVEDSNIVQSKVVRSKQIDLKPMDLEEAILQMDLLGHDFFIYVDVED
                     QTTNVIYRREDGEIGLLEVKES"
     gene            26306..28279
                     /locus_tag="VQ540_000569"
     CDS             26306..28279
                     /locus_tag="VQ540_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HET2544424.1"
                     /translation="MKKFYVSPIFPILVGLIAFGVLSTFIIFVNNNLLTVLILFLFVG
                     GYVFLFKKLRVHYTRSDVEQIQYVNHQAEESLTALLEQMPVGVMKLNLSSGEVEWFNP
                     YAELILTKEDGDFDLEAVQTIIKASVGNPSTYAKLGEKRYAVHMDASSGVLYFVDVSR
                     EQAITDELVTSRPVIGIVSVDNYDDLEDATSESDISQINSFVANFISEFSEKYMMFSR
                     RVSMDRFYLFTDYTVLEGLMNDKFSVIDAFREESKQRQLPLTLSMGFSYGDGNHDEIG
                     KVALLNLNLAEVRGGDQVVVKENDETKNPVYFGGGSAASIKRTRTRTRAMMTAISDKI
                     RSVDQVFVVGHKNLDMDALGSAVGMQLFASNVIENSYALYDEEQMSPDIERAVSFIEK
                     EGVTKLLSVKDALGMVTNRSLLILVDHSKTALTLSKEFYDLFTQTIVIDHHRRDQDFP
                     DNTVITYIESGASSASELVTELIQFQNSKKNRLSRMQASVLMAGMMLDTKNFTSRVTS
                     RTFDVASYLRTRGSDSIAIQEIAATDFEEYREVNELILQGRKLGSDVLIAEAKDTKCY
                     DTVVISKAADAMLAMSGIEASFVLAKNTQGFISISARSRSKLNVQRIMEELGGGGHFN
                     LAAAQIKDVTLSEAGEKLTEIVLNEIKEKEKEE"
     gene            28276..28728
                     /gene="rplI"
                     /locus_tag="VQ540_000570"
     CDS             28276..28728
                     /gene="rplI"
                     /locus_tag="VQ540_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HET2544425.1"
                     /translation="MKVIFLADVKGKGKKGEIKEVPTGYAQNFLIKKNLAKEATAQAV
                     GELRGKQKSEEKAHAEMIAEGKAIKAQLEAEETVVEFVEKVGPDGRTFGSITNKKIAE
                     ELQKQFGIKIDKRHIQVQAPIRAVGLIDVPVKIYQDITSVINLRVKEG"
     gene            28772..30124
                     /gene="dnaB"
                     /locus_tag="VQ540_000571"
     CDS             28772..30124
                     /gene="dnaB"
                     /locus_tag="VQ540_000571"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HET2544426.1"
                     /translation="MAEVEELRVQPQDILAEQSVLGAIFIDESKLVFVREYIESRDFF
                     KYAHRLIFQAMVDLSDRGDAIDATTVRTILDNQGDLQNIGGLSYLVEIVNSVPTSANA
                     EYYAKIVAEKAMLRRLIAKLTESVNQAYEASQPADEIIAQAEKGLIDVSENANRSGFK
                     NIRDVLNLNFGNLEARSQQTTDITGIATGYRDLDHMTTGLHEEELIILAARPAVGKTA
                     FALNIAQNIGTKLDKTVAIFSLEMGAESLVDRMLAAEGLVESHSIRTGQLTDEEWQKY
                     TIAQGNLANASIYIDDTPGIRITEIRSRSRKLAQETGNLGLILIDYLQLITGTGRENR
                     QQEVSEISRQLKILAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYERGGEEEEGIPNNKVEVIIEKNRSGARGTVELIFQKEYNKFSSISKREA
                     "
     gene            30126..30392
                     /locus_tag="VQ540_000572"
     CDS             30126..30392
                     /locus_tag="VQ540_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001278167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2544427.1"
                     /translation="MSDAFTDVAKMKKIKEEIKAHEGQVVEMTLENGRKRQKNRLGKL
                     IEVYPSLFIVEFGDVEGDKQVNVYVESFTYSDILTEKNLIHYLD"
     gene            30481..31827
                     /gene="cbpD"
                     /locus_tag="VQ540_000573"
     CDS             30481..31827
                     /gene="cbpD"
                     /locus_tag="VQ540_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase CbpD"
                     /protein_id="HET2544428.1"
                     /translation="MKILPFIARGTSYYLKMSVKKLVPFLVVGLMLAAGDSVYAYSRG
                     NGSIARGDDYPAYYKNGSQEIDQWRMYSRQCTSFVAFRLSNVNGFEIPAAYGNANEWG
                     HRARREGYRVDNTPTIGSITWSTAGTYGHVAWVSNVMGDQIEIEEYNYGYTESYNKRV
                     IKANTMTGFIHFKDLDGGSVGNSQSSTSTGGTHYFKTKSAIKTEPLVSATVIDYYYPG
                     EKVHYDQILEKDGYKWLSYTAYNGSYRYVQLEAVNKNPLGNSVLSSTGGTHYFKTKSA
                     IKTEPLVSGTVIDYYYPGEKVHYDQILEKDGYKWLSYTAYNGSRRYIQLEGVTSSQNY
                     QNQSGNISSYGSNNSSTVGWKKINGSWYHFKSNGSKSTGWLKDGSSWYYLKLSGEMQT
                     GWLKENGSWYYLGSSGAMKTGWYQVSGKWYYSYSSGALAVNTTVDGYRVNSDGERV"
     regulatory      31910..32012
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            32083..32373
                     /locus_tag="VQ540_000574"
     CDS             32083..32373
                     /locus_tag="VQ540_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000647657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine-binding protein"
                     /protein_id="HET2544429.1"
                     /translation="MKASIALQVLPLAQGIDRIAVIDQVIAYLQTQEVTMVVTPFETV
                     LEGEFDELMRILKEALEVAGQEADNVFANVKINVGEILSIDEKLEKYTETTH"
     gene            32336..33094
                     /locus_tag="VQ540_000575"
     CDS             32336..33094
                     /locus_tag="VQ540_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009013602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2544430.1"
                     /translation="MRNLKSILRRHISLLGFLGVLSIWQLAGFLKLLPKFILPTPLEI
                     LQPFVRDREFLWHHSWATLRVALLGLILGVLIACLMAVLMDSLTWLNDLIYPMMVVIQ
                     TIPTIAIAPILVLWLGYGILPKIVLIILTTTFPIIVSILDGFRHCDKDMLTLFSLMRA
                     NPWQILWHFKIPVSLPYFYAGLRVSVSYAFITTVVSEWLGGFEGLGVYMIQSKKLFQY
                     DTMFAIIILVSIISLLGMKLVDISEKYVIKWKRT"
     gene            33132..34139
                     /locus_tag="VQ540_000576"
     CDS             33132..34139
                     /locus_tag="VQ540_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HET2544431.1"
                     /translation="MKKTWKVFLTLVTALVAVVLVACGQGTASKDNKEAELKKVDFIL
                     DWTPNTNHTGLYVAKEKGYFKEAGVDVDLKLPPEESSSDLVINGKAPFAVYFQDYMAK
                     KLEKGAGITAVAAIVEHNTSGIISRKSDNVSSPKDLVGKKYGTWNDPTELAMLKTLVE
                     SQGGDFEKVEKVPNNDSNSITPIANGVFDTAWIYYGWDGILAKSQGVDANFMYLKDYV
                     KEFDYYSPVIIANNDYLKDNKEEARKVIQAIKKGYQYAMEHPEEAADILIKNAPELKE
                     KRDFVIESQKYLSKEYASDKEKWGQFDAARWNAFYKWDKENGILKEDLTDKGFTNEFV
                     K"
     gene            34139..34867
                     /locus_tag="VQ540_000577"
     CDS             34139..34867
                     /locus_tag="VQ540_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2544432.1"
                     /translation="MTEIRLEHVSYAYGQERILEDINLQVTSGEVVSILGPSGVGKTT
                     LFNLIAGILEVQSGRIVLDGEENPKGRVSYMLQKDLLLEHKTVLGNIILPLLIQKVDK
                     AEAISRADKILATFQLTAVRDKYPHELSGGMRQRVALLRTYLFGHKLFLLDEAFSALD
                     EMTKMELHAWYLEIHKQLQLTTLIITHSIEEALNLSDRIYILKNRPGQIVSEIKLDWS
                     EDEDKEVQKIAYKRQILAELGLDK"
     gene            34986..35444
                     /locus_tag="VQ540_000578"
     CDS             34986..35444
                     /locus_tag="VQ540_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HET2544433.1"
                     /translation="MRFKNTSDHIEAYIKAILDQSGIVELQRSQLADTFQVVPSQINY
                     VIKTRFTESRGYLVESKRGGGGYIRIGRIEFSSHHEMLRELLYSIGERVSQEIYEDIL
                     QLLVEQELMTKQEMNLLESVALDRVLGEEAPVVRANMLRQVIQEVDRKGK"
     gene            35446..37878
                     /locus_tag="VQ540_000579"
     CDS             35446..37878
                     /locus_tag="VQ540_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001109706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HET2544434.1"
                     /translation="MNYSKALNECIESAYMVAGHFGARYLESWHLLIAMSNHSYSVAG
                     ATLNDYPYEMDRLEEVALELTETDYSQDETFMELPFSRRLQVLFDEAEYVASVVHAKV
                     LGTEHVLYAILHDGNALATRILERAGFSYEDKKDQVKIAALRRNLEERAGWTREDLKA
                     LRQRHRTVADKQNSMANMMGMPQTPSGGLEDYTHDLTEQARSGKLEPVIGRDKEISRM
                     IQILSRKTKNNPVLVGDAGVGKTALVLGLAQRIASGDVPAEMAKMRVLELDLMNVVAG
                     TRFRGDFEERMNNIIKDIEEDGQVILFIDELHTIMGSGSGIDSTLDAANILKPALARG
                     ALRTVGATTQEEYQKHIEKDAALSRRFAKVTIEEPSVADSMTILQGLKATYEKHHRVQ
                     ITDEAVETAVKMAHRYLTSRHLPDSAIDLLDEAAATVQNKVKYVKADDSDLSPADKAL
                     MDGKWKQAAQLIAKEEEVPVYKDLVTESDILTTLSRLSGIPVQKLTQTDAKKYLNLEA
                     ELHKRVIGQDQAVSSISRAIRRNQSGIRSHKRPIGSFMFLGPTGVGKTELAKALAEVL
                     FDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVE
                     KAHPDIFNVLLQVLDDGVLTDSKGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKDI
                     RFDQENMEKRMFEELKKAYRPEFINRIDEKVVFHSLSSDHMQEVVKIMVKPLVASLAE
                     KGIDLKLQASALKLLANQGYDPEMGARPLRRTLQTEVEDKLAELLLKGDLVAGSTLKI
                     GVKAGQLKFDIA"
     gene            38520..39173
                     /gene="rr06"
                     /locus_tag="VQ540_000580"
     CDS             38520..39173
                     /gene="rr06"
                     /locus_tag="VQ540_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001024075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RR06"
                     /protein_id="HET2544435.1"
                     /translation="MNILVADDEEMIREGIAAFLTEEGYHVIMAKDGQEVLEKFQDLP
                     IHLMVLDLMMPRKSGFEVLKEINQKHDIPVIVLSALGDETTQSQVFDLYADDHVTKPF
                     SLVLLVKRIKALIRRYYVIEDIWRYQDVTVDFTSYKAHYKNEEIDLKPKELLVLKCLI
                     QHKNQVLSREQILEEISKDVADLPCDRVVDVYIRTLRKKLALDCIVTVKNVGYKISL"
     gene            39170..40510
                     /gene="hk06"
                     /locus_tag="VQ540_000581"
     CDS             39170..40510
                     /gene="hk06"
                     /locus_tag="VQ540_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     HK06"
                     /protein_id="HET2544436.1"
                     /translation="MIKNPKLLTKSFLRSFAILGGVGLVIHIAIYLTFPFYYIQLEGE
                     KFNESARVFTEYLKTKTSDEIPSLLQSYSKSLTISAHLKRDIVDKRLPLVHDLDIKDG
                     KLSNYIVMLDMSVSTADGKQVTVQFVHGVDVYKEAKNILFLYLPYTFLVTIAFSFVFS
                     YFYTKRLLNPLFYISEVTSKMQDLDDNIRFDESRKDEVGEVGEVGKQINGMYEHLLKV
                     IHELESRNEQIVKLQNQKVSFVRGASHELKTPLASLRIILENMQHNIGDYKDHPKYIA
                     KSINKIDQMSHLLEEVLESSKFQEWTECRETLTVKPVLVDILSRYQELAHSIGVTIEN
                     QLTDATRVVMSLRALDKVLTNLISNAIKYSDKNGRVIISEQDGYLSIKNTCAPLSDQE
                     LEHLFDIFYHSQIVTDKDESSGLGLYIVNNILESYQMDYSFLPYEHGMEFKISL"
     gene            40593..41120
                     /locus_tag="VQ540_000582"
     CDS             40593..41120
                     /locus_tag="VQ540_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenylcysteine carboxyl methyltransferase
                     family protein"
                     /protein_id="HET2544437.1"
                     /translation="MVLAIILVTFFIRLIFLKRSIENEKRILSNGGKEFGVENTKRLT
                     MAHIVFYLSCLVEAMVHKTIFDGMGMVGLVLLIFSMLMLMLVIHLLGDIWTVKLMLVN
                     NHKYVDHILFRTVKHPNYFLNILPELIGLTLLSHAYVTFVLVFPVYAVILYRRIAEEE
                     KLLHEVIIPNGSIKR"
     gene            41199..>42370
                     /locus_tag="VQ540_000583"
     CDS             41199..>42370
                     /locus_tag="VQ540_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RICH domain-containing protein"
                     /protein_id="HET2544438.1"
                     /translation="MFASKSERKVHYSIRKFSIGVASVVVASLFLGGVVHAEGVRSGD
                     TPKVTSSGDEVESHLKKILSEIQTQLDRKRHAKTVALINKLQDIKRTYSYKLNVLEEK
                     PKAELTSKTKEELTAAFEQFKKDTLPTEPGKKVAEAEKKVAEAEKKAEDQKEEDRRNY
                     PTNTYKTLELEIAEFDVKVKEAELELLKEKAKKPLNEGTIKQAKEKVESKKAEATRLE
                     NIKTDRKKAEEEAKRKAAEEDKVKEKPAEQPQPAPAPQPEKPAPKPEKPAPAPKPENP
                     AEQPKAEKPADQQAEEDYARRSEEEYNRLTQQQPPKTEKPAQPSTPKTGWKQENGMWY
                     FYNTDGSMATGWLQNNGSWYYLNSNGAMATGWLQNNGSWYYLNANGSMATGWLQNNG"
BASE COUNT        13381 a         6921 c         9139 g        12929 t
ORIGIN      
        1 gctttagatc tttagaaaac cttgaacaag ctattgtgga ctacattgat tactacaaca
       61 acaaacgaat taaggtaaaa ctaaaagaac ttagccctgt gcaatacaga actaaatcct
      121 tcggataaat taattgtcta actttttggg gtcagtacat taactggtcg attttttatg
      181 ccttagatga ctttcgtctg tgattataga ttccaaatag taagagagaa gtaaaggaac
      241 agattgctcc agtaataaaa ccattgggaa tgaaggaaag tgtaatagtt cctttcccct
      301 tgggaatgtc aactttcata aatccagttt gagcttgttt aatttctatt ttcttaccat
      361 cttggtaggc agaccaacct ttgtcataag gaatggtgaa gaaaatagat gtatcttgtt
      421 ggacatcata tgtagcaaaa accttgtttt tagaagttga tactgtgaca ggttgttctt
      481 taattttttg aattgcctcg gtgaaagttt tggtatctaa acgatagaag gtaggagatt
      541 caaatgatac ttgtgaattt ccagggaaac taacattgat attgaaagtt tttttctctt
      601 tagtatatcc tagattaaag aaggagaaga cattatcagt tgtaaaagtc tttttttcac
      661 catttacaag gatgtcaacc ttcttttgtt tatcgttaga aaagtgaagg tttatgaaag
      721 agagataaac ttggctgttt tctggaactt caatttgata ctggattgct gcatcttcat
      781 ttgaagaact tgtgacacta atcaaatcat tagtattttc tgttttttca taaggtattg
      841 gagaaaaata atcaaaattg acgttagcaa gttgatttaa aaatgaggcc tgattatcca
      901 aggtatgttc attgaacttg acatcattgt aaacagattg actagcaact gcaatcggaa
      961 gagagtattg attttcatat agggtaagat tatctttttg atagatatct ttaaagccat
     1021 acttatcaat aggactgtct gagatattgt actggatacc aaataaacta tcagccaaaa
     1081 tactattatt tgcatatcgg agattgagat tagtcccaga ggatttaaaa ccaagtttat
     1141 ctaaagtaga gcttgatgaa cgatttcgaa cagatgaaaa ttgagagatt ccattgtagt
     1201 tgaatttcat actgtcattt cctgtctgag tttgtagttt ttcagtacga gtaaattgat
     1261 ttccaatata tgttgagaaa gattccatag ctgggatatc tcgactataa gcacttcgag
     1321 aagcaaatcc ccattcctta gcaattccgt ccatttgaga tgaagcattt aaactcattt
     1381 caaccagtat aaataaagag attagaatgg caaatagatt cacagatata aactttttga
     1441 taactgcaag gagtaaaaga gaatagacaa ccaaaaattc aagagtaagc agaatattca
     1501 aatctgttaa aaaagaataa tgcgatttta gatagatggt agctaaaaat cctgctacta
     1561 caagaaaaag cgaaactaaa aaattccaga ctttaagttc tttcagacgc tttaagactt
     1621 ctgctgctgt gtaaattaac aaggtagaga aaatccaagc atagcgatgt aaaaacatgt
     1681 ttggagtatg catgccttgc caaaataagt caagagcttc tatgtaaaag cttgcaatta
     1741 gaaatgcaaa gaatattaca tatatgagtt tcacgtgaaa cttaatagat ttcagcgtaa
     1801 aaaataaaat ggtcaaaata aagggaaata gtccaacaaa aatcattggg atggccccat
     1861 actttgttgt gtcaaaggaa ccaatgaatt gcttagcaaa gagatcaaga taccagctac
     1921 tttcagtttg aaactttgta acttcagtca atttttcccc atgtgtctgt aaatcaaata
     1981 gagtgggaag agtcataatc aaactagcca taccagctaa aaaggagata actatgaaat
     2041 caagaacaga tgattttcga gtcttaaagt cccacgaaat ttgacagaga taccagaaaa
     2101 taagaaacaa tactgtcata tatccaaaat aataattttg aataaataag attgacagac
     2161 ttgtaaagta caataggagt ttcttttcag ttatcagtag atgtaaacca gttataatta
     2221 aaggaatcaa gataaaaaca tctagccagg tttttatctc taattgactg acagtgaaac
     2281 tcatcagagc ataggaagta gataaggcta gttttaaagt ctgagggata gattgaaaca
     2341 atttattcaa actaaaaaag gttgacagac caatcaatcc aaattttaag agagtggtca
     2401 gatagacagc atctggcata ttcgttagat caaaaaagta aactagaggc gcgagaaaac
     2461 tacccaagta ataactagat agggcataga agtttagccc tagaccactt gtaaaggtgt
     2521 aaaacagact actatttcca tgtaggatat ttcgtaaggc tacatcaaaa ataacgtatt
     2581 gatgaaagcc atctcctaat agaggagagt tgtcgctatt ccagtagata ccttgagata
     2641 gatatactcc agacataatc actacaggaa tgatgaaaga aataaaatag gttcgatatg
     2701 tttttaaaaa tgatttcatg ttacctcgta gaatgataga aaactcagtt ggttaaccca
     2761 actgagtttt gaagttttat ttagtctttc caaagttctt taacttttgc ttgtacttct
     2821 gcattttcta ggaattcatc gtaggtttca tcgatacggt caatgacgcc atttttagat
     2881 aagacaatga tatggttagc caaagtttga ataaactcgt ggtcatggct ggcaaagatg
     2941 attgattctt taaagttttt cagtccatca ttcaagcttg agatagattc caagtccaag
     3001 tgatttgttg gatcatcaag tacaaggaca tttgatttta agagcatgag ttttgaaagc
     3061 atgacacgaa ctttttctcc ccctgacaag acatttacag gtttgttaac ttcatctcca
     3121 gagaagagca tacggccgag gaaaccacgt aggaaagtat tgtcatcttc ttctttactt
     3181 gcgaattgac gcaaccagtc aagaattgat tctcctcctg caaaatcagc tgagttatct
     3241 tttggtaggt aagattgact agttgtaact ccccacttga cagttccttc atagtcaata
     3301 tctcccatga ttgcacgaat taatgcagtc gtttgaatat cattttgtcc aataagtgct
     3361 gtcttatcat ctggacgcaa gatgaaacta atattatcca agatagtttc accatcaatc
     3421 tttacagtta gattttctac tgtcaagaga tcattaccaa tctcacgttc cgctttaaag
     3481 ttgataaatg gatatttacg actagatggt acaatctctt ctagctcaat cttatcaagc
     3541 attttcttac gtgatgttgc ctgccttgac ttagaagcat tggcagagaa acgagcaacg
     3601 aattcttgca attgtttaat tttttcttct gctttagcat tacggtctgc tagcaattta
     3661 gcagcaagct cagaagattc cttccagaag tcgtagtttc cgacatagag tttgattttt
     3721 ccaaagtcaa ggtcggccat gtgagtacaa actttgttta agaagtgacg gtcgtgggat
     3781 actacgataa ctgtgttatc aaagtcaatc aagaagtctt ctaaccaagt aatcgattgg
     3841 atatccaaac cgttagtagg ctcgtccaag agaagaacat ctggtttacc aaaaagtgct
     3901 ttggcgagga gaacctttac tttttcaccg ttggccaatt cgctcatgtt ttggtagtgt
     3961 aattcttctg gaatgtttag gttttgaagt agttgagagg cttcactctc tgcttcccaa
     4021 cctccaagtt cggcaaactc tccttcgagt tcggcagcac gaaccccgtc ctcgtctgag
     4081 aaatcttcct tcatgtagat agcatctttc tctttcatga tgctataaag tttttcattt
     4141 cccatgataa cgacatcaat ggcacgttca tcttcgtagt caaagtgatt ttgacgaaga
     4201 acagagagac gttcatctgg accaagagag atgtgaccag tagtaggttc gatatctcca
     4261 gctaaaattt ttaaaaaggt tgattttccg gcaccattag caccgattaa tccgtaagta
     4321 tttccttctg taaatttgat attgacatca tcaaaaagtt tgcgatcact aaaacgtagt
     4381 gaaacatcag atactgtaag caatgttttt ctcctatatg tgtaatatat ttattctact
     4441 agaaaataca gaaatattca aatttttatt tgtcaatttt gtgtaaatta tatttacagt
     4501 atcctttaca caaatctgta aaaagcaagg ctgatttatt ttgataaatt acggttattt
     4561 cattaaaaaa atgctataat tgaaaggact atatcgaagg agaacaaaat gactaaaccc
     4621 attattttaa caggagaccg tccaacagga aaattgcata ttggacatta tgttggaagt
     4681 ctcaaaaatc gagtattatt acaggaagag gataagtatg atatgtttgt gttcttggct
     4741 gaccaacaag ccttgacaga tcatgccaaa gatcctcaaa ccattgtaga gtctatcgga
     4801 aatgtggctt tggattatct tgcagttgga ttggatccaa ataagtcaac tatttttatt
     4861 caaagccaga ttccagagtt ggctgagttg tctatgtatt atatgaatct agtttcgtta
     4921 gcacgtttgg agcgaaatcc aacagtcaag acagagattt ctcagaaagg atttggagaa
     4981 agcattccga caggattctt ggtctatcca atcgctcaag cagctgatat cacagctttc
     5041 aaggctaatt atgttcctgt tgggacagat cagaaaccaa tgattgagca aactcgtgaa
     5101 attgttcgtt cttttaacaa tgcatataac tgtgatgtct tggtagagcc ggaaggtatt
     5161 tatccagaaa atgagagagc agggcgtttg cctggtttag atggaaatgc taaaatgtct
     5221 aaatcactaa ataatggtat ttatttagct gatgatgcgg atactttgcg taaaaaagta
     5281 atgagtatgt atacagatcc agatcatatc cgcgttgagg atccaggtaa gattgaggga
     5341 aatatggttt tccattatct agatgttttt ggtcgtccag aagatgctca agaaattgct
     5401 gatatgaaag aacgttatca acgaggtggt cttggtgatg tgaagaccaa gcgttatcta
     5461 cttgaaatat tagaacgtga actgggtcct attcgtgagc gccgtattga atttgctaag
     5521 gatatgggag aagtttataa tatgattcaa aaaggtagtg aaagagcgcg tgaagttgcg
     5581 ggtcaaaccc tatctgaggt aaaaggggca atgggacttc attactttaa ctaagtttat
     5641 tttacaagaa actatcattt ctatctcgaa gaaaagatag tttttttatt tacccctgta
     5701 acatttgaca aatttttata gaatggtatg atagatacaa tataaaaaga gtcaagctca
     5761 aaaagaaaga aaagaggaaa cttcgaatgt ctaattggga cactaaattt ttgaaaaaag
     5821 gttttacctt tgatgatgta ttgcttattc cagctgaaag tcatgtgttg cctaacgatg
     5881 cagatttaac aactaaattg gcagataatt tgactttaaa tatcccaatt attaccgctg
     5941 ccatggacac agttacagag agtcaaatgg ccattgctat tgctcgtgca ggcggtctcg
     6001 gagttatcca taaaaacatg tcaattgctc aacaagcaga cgaggttcgt aaggtaaaac
     6061 gttctgaaaa tggagttatt attgatccgt tcttcttgac gcctgaacat acaattgctg
     6121 aagcagatga gcttatgggt cgttaccgca tcagtggtgt tccagttgtt gaaacacttg
     6181 aaaatcgtaa attggttggt attttgacaa accgagatct tcgttttatt tcagattata
     6241 atcaaccaat ttcaaaccat atgactagtg aaaatcttgt tactgctcct gtgggtacgg
     6301 atcttgcaac ggctgagagt attcttcaag agcatcgtat tgaaaaactt ccgttggtcg
     6361 atgaagaagg cagtctttct ggtttgatca ctatcaaaga tattgaaaaa gttattgagt
     6421 ttccaaatgc ggctaaagat gagtttggtc gtcttctagt tgcaggtgca gtaggtgtta
     6481 cttcagatac atttgaacgt gcagaggctc tttttgaggc aggagcggat gcgattgtta
     6541 ttgatactgc acatggtcat tctgcaggtg tcttgcgtaa aattgccgag attcgtgctc
     6601 atttcccaga tcggactttg attgctggaa atattgctac tgctgaaggt gcacgtgccc
     6661 tttatgaagc gggtgtagac gttgttaagg ttggtattgg accaggttct atctgtacta
     6721 ctcgtgtgat tgctggtgtt ggtgttccgc aagtaacagc tatctacgat gctgcagctg
     6781 ttgcgcgcga atatggtaaa acgattattg ctgacggtgg gatcaagtat tctggagata
     6841 ttgtaaaagc acttgctgca ggtggaaatg ctgttatgct tggatctatg tttgctggaa
     6901 ctgatgaagc tccaggcgaa actgaaatct tccaaggacg taaattcaag acttaccgtg
     6961 gtatgggatc aattgctgct atgaagaaag gttcaagcga ccgttatttc caaggttctg
     7021 tcaatgaagc aaacaagctt gttccagaag gaattgaagg tcgtgttgct tataaaggag
     7081 cggcagctga tattgttttc caaatgattg gtggtattcg ctctggtatg ggttactgtg
     7141 gtgcagctaa ccttaaagaa ctacacgata atgctcaatt tattgaaatg tctggtgctg
     7201 gtttgaaaga aagccatcct catgatgtgc aaattactaa tgaggcacca aattattcta
     7261 tgtaaaaaac aatgaaaaga actccagtga aaacaggagt tcttttacaa tgttgtcaat
     7321 ttccatttac agcagcttta ccatcctgaa tagtgaagat acttagattt tctggcagat
     7381 tttgaagatg gtctaagctt gttgttgtga taaaggtttg gattgattga gaaatcgttt
     7441 ctaataattt taactgtcta gtgttgtcaa gttcactcat cacatcgtca agcagtaata
     7501 taggagattc tgtggtaatg ctttccatta attcgatttc tgctaatttt atcgagagga
     7561 cgagactacg atgttgacct tggcttccga aactagcatc catcccattt atataaaaag
     7621 aaatgtcatc tcgatgagga ccgacaccag tattcttttt aaataaatct ctggatctac
     7681 ttttttctaa agcaattttg aaagattcgg ataagttttg tttgtcagtt atattgacag
     7741 aagattgata ggatattgac aactcttcga tctgattaga gagttcaaaa tgtttcttac
     7801 gcccaaatga ttctagtttt tttatgaaat ctaagcggtg attcattaca cgacatccat
     7861 aatcaactag ctgatcatct aacacagaaa ggaatgtttc atctattttt tgagctgatt
     7921 ttaggtaagt gtttctttgc tttaggatgt ggttataatt ggttaagtca gataaataga
     7981 ttggcttaat ttgcccaagt tccatatcaa tgaattttcg tcgaatcgaa ggtgctcctt
     8041 taattagttg taaatcttca ggagcaaata agacaacatt catgtgtcct acataatctg
     8101 aaaggcgtgc ctgttttaag tgattaactt ttgttacacg gcctttttgt gttagttcga
     8161 tttctagggg aatggatcca gtttttttct gaacgagacc tgaaagatga agttgttcct
     8221 catcaaaatg aatgagattt ttatctgttc gagttcgatg actacgcgtt aaggctaaaa
     8281 aatagatagc ctctaacatg tttgtttttc cttgtgcatt acgtcccaaa aagacattca
     8341 atttaggatt aaagtctatt ttcgtttctt tgtaattacg aaaagtcttg agagatagat
     8401 gttgtagcca catgattatc taccagggaa tcgtggagct tgttggcttt taggtgatga
     8461 agcaggtttc gatttgtctt ttttaactcc cttattcatc tttttgacaa gtttagcgat
     8521 ccgttctttt tcaactttat cagcttggta ttcatcttgt tcttcagaag tagattgtgt
     8581 caacaagatg tcaatgttca tgtcagggat gtcaatttta tcgccaatac gaagtttttt
     8641 accacgacga ctctctaatt ccctattaaa gtaaacagaa tgttcagaga gaaatgattt
     8701 aatagctcct ccgctatgtg taattccaag ttctttgagt agtgcttgga gggtaataaa
     8761 ttcttcaaat aatttgtatt ccataattca cctcaatctt tggtattata ccatattttc
     8821 ctaaaaatag tgagagatac agcgagaaat gtaagcgatt tttatttcaa aagtgttaca
     8881 gggaacaaga aaatttcagg ttttcgtgat ataatagaag tctgtatata aggagataaa
     8941 tcatggagtt agtgcatgga atttcaacac attttatcca atcaaaaaag tttaaaacaa
     9001 acaaaattac cgtgcgtttt accgctccat tatcccttga tacgattgca ggtcacatgt
     9061 tgagtgcaag tatgctagag actgctaatc agatgtaccc cacttctcaa gatttgagga
     9121 gacacttggc cagtctatac ggtacagata tgtcaaccaa ttgtttcaga agagggcaaa
     9181 gccacattat agaattgaca tttacctatg ttcgtgatga gtttttaagt aggaaaaacg
     9241 tgctaacttc tcagattttg gaacttgtaa aagaaactct tttttcaccc gtagtagttg
     9301 ataatgggtt tgatccggcc ttatttgaaa ttgagaaaaa acaattgcta gcaagtttag
     9361 cagctgatat ggatgattct ttttattttg cacataaaga attggataaa ttgttttttc
     9421 atgatgaacg tcttcaattg gaatatagtt atttacgaaa tcgtatttta gctgaaactc
     9481 cacaaagttc ttattcttgt ttccaagaat ttttagccaa tgatcgaata gatttctttt
     9541 tcctaggtga ttttaatgag gttgaaattc aaaatgtatt agaatcattt ggctttaaag
     9601 gtcgaaaagg agatgtgaag gttcagtatt gtcaacctta ttctaatatc cttcaggaag
     9661 gtatggttcg gaaaaatgtg ggacaatcca ttttggaatt aggttatcat tgcccttcta
     9721 aatatggtga tgagaaacat ttacccatga ttgtaatgaa tggtttactt ggtggatttg
     9781 ctcactctaa actttttaca aatgtccgtg aaaatgctgg attagcttat actatttcaa
     9841 gtcagctcga tttatttagt ggattcttga ggatgtatgc tggtattgac cgagaaaatc
     9901 gtaaccaggc tcgtaaaatg atgaataatc aactgcttga tttaaaaaaa ggttatttta
     9961 cagagcttga gttagagcag accaaggaaa tgattcgtcg gtctttgtta ctttctcaag
    10021 ataaccaatc ttcattgatt gaacgtgctt atcaaaatgc cttacttgga aaatcttcag
    10081 cagattttaa aagttggatt gcaaaactcg agcaagttga caaagatgct atttgtagag
    10141 cagctaacaa tgtgaaacta caagcgattt actttatgga aggaatagaa tgacaaaggt
    10201 tgtttttgaa gaaaaatact atccagctgt aaaagaaatg gtttatcgaa ctcgtttggc
    10261 aaatggattg acagtagctc ttttgcctaa aaaggaattt aaagaggttt acgggagtgt
    10321 aactgtacag tttggttcgg tagatacgct tgtcacagaa gttgatggag atgtaaaaca
    10381 atatcctgca ggaattgctc attttcttga acataaatta tttgaaagag aagattctag
    10441 cgatttgatg tcggctttta cgagtctagg tgcagatagt aatgccttta caagctttac
    10501 aaaaacaaac tatctttttt cagcaacgga ttatttttta gaaaatttag atttacttga
    10561 tgaattgata acatcagcac actttactga agcttccatt ctgacagagc aggatattat
    10621 tcagcaagaa cgagaaatgt accaagatga tccagattcg tgtttattct tttcaacttt
    10681 agcgaatttg tatcctggta cacctttagc aactgatata gttggaagtg aggagtccat
    10741 ttcccaaatc aatctaacta atttgcaaga aaattttaca aagttttaca aacctgtaaa
    10801 catgtctctg tttttagttg gtaattttga tgtggagcga gtacaggact attttgaaag
    10861 caaagaactg aaagattcag attttcagga agtagcaaga gaaaagttgt ttttacagcc
    10921 tgtaaagcta acagatagta tgagaatgga agtatcttct cccaaactag cgattggagt
    10981 tagaggtaag cgagaagttt ctgaagcgga ttgctatcga catcatattt tattaaaatt
    11041 attgtttgca atgatgtttg gttggacttc ggatcgtttt caaaaatgtt atgaatcagg
    11101 taaaattgat gcgtccttat ctctggaagt tgaaataaca agtcgctttc attttgtcat
    11161 gttgacaatg gatacgaaag agccagttgc tttgtctcat caatttagga aggctattcg
    11221 taattttaca aaggatttag atattacaga ggaacattta gatattatca aaagagagat
    11281 gtttggcgaa tttttcagta gcatgaactc tcttgaattt attgcaacgc aatatgatgc
    11341 ttttgaaaat ggtgagacaa tttttgattt gccgaaaatt ttacaggaaa ttactttaga
    11401 ggatgtcctt gatgctggac atcatttaat agatgatggt gacatagttg attttacaat
    11461 atttccatcg tagtaaccta tcataataga cactagaaag aagggatgac aagtatgaga
    11521 aaaaaaacaa ttggagaggt tttacgatta gctagaatca atcagggatt gagtttagat
    11581 gaattgcaga aaaagacaga aatccagtta gatatgttgg aagcaatgga agcagacgat
    11641 ttcgatcaac ttccaagtcc tttttacacg cgttctttct tgaaaaaata tgcatgggct
    11701 gttgagttag atgaccaaat tgttttggat gcttatgatt ctgggagtat gattacttat
    11761 gaggaagtag atgttgatga agatgagttg acaggtcgta gacgttcaag taagaaaaag
    11821 aagaaaaaaa catcattttt acctttattt tattttatcc tttttgcttt atcgatttta
    11881 atttttgtga cttattatgt ttggaactat attcaaactc aaccagagga gccttctctt
    11941 tctaattaca gtgtggttca atcaacaagt tcaactagct ctgttcccca ctcctcaagt
    12001 agtagttctt ctagtataga atcagctata agtgtatcag gcgaaggaaa tcatgtagaa
    12061 atcgcttata agacaagtaa ggaaacagtt aaattgcaat tggcagtttc agatgttaca
    12121 agttgggtca gtgtttcaga aagcgaactt gagggcggtg taaccttatc gccaaagaag
    12181 aaaagtgcag aagcaacagt tgcaactaaa agtcctgtaa caattacgtt aggtgttgta
    12241 aaaggtgttg atttgacagt agataatcag actgttgatt tatcgaaatt aacagctcag
    12301 actggacaaa tcactgtaac ctttactaaa aattaaggaa aaacgaatga aaaaagaaca
    12361 aattcccaat ctcttaacaa taggtcgaat tctctttata cctattttta tctttatttt
    12421 aacgatagga aattcgatag agagtcatat agttgcagct attatctttg ctgttgccag
    12481 tattaccgac tatttagatg gatatttagc tcgtaaatgg aatgtggtca gtaattttgg
    12541 taaatttgca gatcctatgg cggataagtt actagttatg tcggctttta ttatgttgat
    12601 tgagttaggt atggctccgg cttggattgt tgcagtgatt atatgtcgtg agttagctgt
    12661 gacaggttta aggcttttat tggttgaaac tggtggaaca attttagcag cagcaatgcc
    12721 tggaaaaatt aaaactttta gtcagatgtt tgctattatt ttcttgctat tacattggac
    12781 tttgcttggt caagttctac tttatgtagc cttatttttc actatctact ctggctatga
    12841 ctattttaag ggtagtgcct atgtatttaa agggacattt ggttcgaaat gaaatcaata
    12901 attgatgtaa aaaatctttc ttttcgctat aaagaaaatc agaactacta cgatgtgaag
    12961 gatattacgt ttcacgtgaa acgtggagaa tggctttcga ttgtagggca taatggtagt
    13021 ggtaaatcaa cgacggttcg attaattgat ggcttactgg aagcagaatc cggagagatt
    13081 gtaattgatg gccaacgttt gactgaggaa aatgtttgga atatacgtcg tcaaatcggt
    13141 atggtttttc aaaatccaga caatcaattt gttggagcga ctgttgaaga tgatgttgct
    13201 tttggtttgg aaaatcaggg actttctcgt caagaaatga aaaagagagt ggaagaagct
    13261 ctggctttag ttggcatgtt ggactttaaa aagagagagc cagcgcgtct atcaggtggt
    13321 caaaagcaac gtgtggccat tgcaggtgtt gtagccctaa gaccagctat tttaatctta
    13381 gatgaagcaa cgagtatgtt ggatcctgag gggcgtagag aacttattgg gacagtaaaa
    13441 ggaattcgaa aagactatga tatgacggtc atttctatta cccatgattt ggaagaagtc
    13501 gccatgagtg atcgcgtatt ggtcatgaaa aaaggggaaa ttgaatcaac tagtagtcca
    13561 agggagcttt tctctcgaaa tgatttagat caaattggat tagacgatcc ttttgctaat
    13621 caattaaaaa aatctttgag ccagaatggc tatgatttac ctgaaaatta tttgacagaa
    13681 agtgagctag aggataagct atgggaattg ctctagaaaa tgtgaatttt acatatcaag
    13741 aaggtactcc cttagcttca gcagctttgt cggatgtttc tttgacgatt gaagatggct
    13801 cttatacagc tttaattggg cacacaggta gtggtaaatc aactatttta caactcttaa
    13861 atggtttatt ggtgccaaat caagggagtg tgagggtttt tgatacctta atcacctcga
    13921 cttctaaaaa taaagatatt cgtcaaatta gaaaacaggt tggcttggta tttcagtttg
    13981 ctgaaaatca gatttttgaa gaaacggttt tgaaggacgt tgcttttgga ccgcaaaatt
    14041 ttggagtttc tgaagaagat gctgtgaaga ctgcgcgtga gaaactggct ctggttggaa
    14101 ttgatgaatc actttttgat cgtagtccgt ttgagctgtc agggggacaa atgagacgtg
    14161 ttgccattgc aggcatactt gccatggagc cagctatatt agtcttagat gagccaacag
    14221 ctggtctaga tcctctaggg agaaaagagt tgatgaccct gttcaaaaaa ctccaccagt
    14281 cagggatgac catcgtcttg gtaacgcatt tgatggatga tgttgctgaa tatgcgaatc
    14341 aagtctatgt aatggaaaag ggacgtttag taaagggggg caaaccaagt gatgtctttc
    14401 aagacgttgt ttttatggaa gaagttcagt tgggagtacc taaaattacg gccttttgta
    14461 aacgattggc tgatagaggc gtgtcattta aacgattacc gattaagata gaggagttca
    14521 aggagtcgct aaatggatag tatgatttta gggcgttata tcccagggga ttcgattgtt
    14581 caccgattgg atccacgtag caaattgctt gctatgatgc tactgatttt gattgtgttt
    14641 tgggctaata accccttgac gaatctgatt ctttttatag cgacagggat atttattgcc
    14701 ttgtcaggag tatctctttc attttttatt cagggcttga agtctatgtt tttcttgatt
    14761 gccttcacaa ctatttttca actatttttc atttctaatg ggaatgtttt atttgagttt
    14821 tcgtttgtga gaatcacgga ttatgctttg caacaagctg ggattatttt ttgtcgcttt
    14881 gtattgatta ttttcttttc aactttgtta accttaacaa ccatgccttt aagtttggca
    14941 tcagctgtcg aagctttatt agcaccttta aagcgtgtga aagttccagt tcatgaaatt
    15001 ggattgatgc tgtctatgag tttgcgtttt gtcccaacct tgatggatga tacgactcgg
    15061 attatgaatg cacagaaagc tcgtggagtg gattttggag aaggaagcat cgttcaaaaa
    15121 gtaaaggcga tgattcccat tttgattcct ctttttgcga caagtttaaa acgtgcagat
    15181 tccttggcta tcgctatgga agcgcgtggc tatcagggtg gaaaaggcag aagtcaatac
    15241 cgacaattga aatggactct aaaggatacg ctgaccattc ttgttattct cgtacttggt
    15301 tgttgtttat ttttcttaaa atcttagtag ctttcaggaa ttgataaaaa gttactgtaa
    15361 cagtttttga tataaaggta ggaatatgaa ccgttttaaa aaatcaaaat atgtcattat
    15421 tgtttttgtc actgttctgc ttgtgtcagc tctcttagcg acgacttatt caagtacaat
    15481 tgtgacaaaa ttaggagatg gaatctcatt ggttgataga gttgtacaaa aaccttttca
    15541 gtggtttgat tctgtcaaat cagatttggc tcatttgaca cgaacatata atgaaaatga
    15601 aagtttgaag aaacagcttt accaattaga agttaaatca aatgaggtgg aaagtttaaa
    15661 gacagaaaat gaacaactgc gccaattgct tgatatgaag tctaaattgc aagccacaaa
    15721 gactttagca gcagatgtta ttatgcgttc tccggtatct tggaagcagg agttgacctt
    15781 agatgcaggt agatcaaaag gtgcttctga gaacatgtta gctattgcaa atggtggctt
    15841 gattgggagt gtttcaaaag tagaggagaa ctctactata gtcaaccttc tgacaaatac
    15901 ggaaaatgct gataagattt ctgttaaaat tcaacatggc tctactacaa tttatggaat
    15961 tattattggc tatgacaagg aaaatgacgt tcttaaagtt agccaattaa atagtaatag
    16021 cgatattagt gcgggagata aggtgactac tggtggatta ggaaacttta acgttgctga
    16081 tattcctgtt ggtgaagtgg ttgccacaac gcatagtaca gactatttga cacgagaagt
    16141 aactgttaaa ttgagtgcag atactcataa tgtagatgtg atagaattag tggggaattc
    16201 ataatgagac agttgaagcg agttggagta tttttattgc ttcctttctt tgttctaatt
    16261 gacgcccata ttagccagct tctgggctca tttttccccc atgtacattt ggctagtcat
    16321 tttctttttc tatttctctt atttgagacg atagaagtat cagagtatct ctacctagtc
    16381 tattgttttg ttataggctt ggtttatgat gtttactttt tccatctaat agggattaca
    16441 actctcttat ttatcttatt gggagccttc cttcataaat tgaatagtgt tattttgttg
    16501 aatcgttgga caagaatgct agctatgatt gtactgacat tcctgtttga aatgggtagt
    16561 tatcttttgg cttttatggt agggttgaca gtagatagca tgtcgatttt tatagtctat
    16621 agcttggtac cgacgatgat tttaaatttt ttatggatta ctgtttttca atttattttt
    16681 gaaaaatatt atctataaga acgacatata aatgtaacaa aggcgtaata tttattaggc
    16741 ctttttttgg tatactagta ttgtctttaa aagaaggagt atctacgtaa tatgaagaaa
    16801 aaaatcttag cgtcactttt attaagtaca gtaatggttt ctcaagtagc tgttttaaca
    16861 actgcgcatg cagaaacgac tgatgacaaa attgctgctc aagataataa aattagtaac
    16921 ttaacagcac aacaacaaga agcccaaaaa caagttgacc aaattcagga gcaagtatca
    16981 gctattcaag ctgagcagtc taacttgcaa gctgaaaatg atagattaca agcagaatct
    17041 aagaaactcg agggtgagat tacagaactt tctaaaaaca ttgtttctcg taaccaatcg
    17101 ttggaaaaac aagctcgtag tgctcaaaca aatggagccg taactagcta tatcaatacc
    17161 attgtaaact caaaatcaat tacagaagct atttcacgtg ttgctgcaat gagtgaaatc
    17221 gtatctgcaa acaacaaaat gttagaacaa caaaaggcag ataaaaaagc tatttctgaa
    17281 aaacaagtag caaataatga tgctatcaat actgtaattg ctaatcaaca aaaattggct
    17341 gatgatgctc aagcattgac tacgaaacag gcagaactaa aagctgctga attaagtctt
    17401 gctgctgaga aagcgacagc tgaaggggaa aaagcaagtc tattagagca aaaagcagca
    17461 gctgaggcag aggctcgtgc agctgcggtg gcagaagcag cttataaaga aaaacgagct
    17521 agccaacaac aatcagtact tgcttcagca aacactaact taacagctca agtgcaagca
    17581 gtatctgaat ctgcagcagc acctgtccgt gcaaaagttc gtccaacata cagtacaaac
    17641 gcttcaagtt atccaattgg agaatgtaca tggggagtaa aaacattggc accttgggct
    17701 ggagactact ggggtaatgg agcacagtgg gctacaagtg cagcagcagc aggtttccgt
    17761 acaggttcaa cacctcaagt tggagcaatt gcatgttgga atgatggtgg atatggtcac
    17821 gtagcggttg ttacagctgt tgaatcaaca acacgtatcc aagtatcaga atcaaattat
    17881 gcaggtaatc gtacaattgg aaatcaccgt ggatggttca atccaacaac aacttctgaa
    17941 ggttttgtta catatattta tgcagattaa tttacagagg gactcgaata gagccctctt
    18001 ttcaggtttt accgtgacaa tccctattaa aaattatatc aaaatagctt gaaaatattg
    18061 gaaaagtatg gtaaaatgaa aattgtcgtg tgaacgataa tactcattct tgatgaattg
    18121 tgaagcagtt gcccttgggt cgttttgcga gttgaagtca agaagaggaa aaaaacaaaa
    18181 aggagaaata ctcatggcag taatttcaat gaaacaactt cttgaggctg gtgtacactt
    18241 tggtcaccaa actcgtcgct ggaatcctaa gatggctaag tacatcttta ctgaacgtaa
    18301 cggaatccat gttatcgact tgcaacaaac tgtaaaatac gctgaccaag catacgactt
    18361 catgcgtgat gcagcagcta acgatgcagt tgtattgttc gttggtacta agaaacaagc
    18421 agctgatgca gttgctgaag aagcagtacg ttcaggtcaa tacttcatca accaccgttg
    18481 gttgggtgga actcttacaa actggggaac aatccaaaaa cgtatcgctc gtttgaaaga
    18541 aattaaacgt atggaagaag atggaacttt cgaagttctt cctaagaaag aagttgcact
    18601 tcttaacaaa caacgtgcgc gtcttgaaaa attcttgggc ggtatcgaag atatgcctcg
    18661 tatcccagat gtgatgtacg tagttgaccc acataaagag caaatcgctg ttaaagaagc
    18721 taaaaaattg ggaatcccag ttgtagcgat ggttgacacc aatactgatc cagatgatat
    18781 cgatgtaatc atcccagcta acgatgacgc tatccgtgct gttaaattga tcacagctaa
    18841 attggctgac gctattatcg aaggacgtca aggtgaggat gcagtagcag ttgaagcaga
    18901 atttgcagct tcagaaactc aagcagattc aattgaagaa atcgttgaag ttgtagaagg
    18961 cgacaacgct taatttatac aaatagtaat tacctaggag ggcggggctt agcccggctc
    19021 tcctattttc aaaaaatata ggagaattaa aatggcagaa attacagcta aacttgtaaa
    19081 agagttgcgt gaaaaatctg gtgccggtgt tatggacgct aaaaaagcgc ttgtagaaac
    19141 agacggtgac atcgaaaaag cgattgaatt gcttcgtgaa aaaggtatgg ctaaggcagc
    19201 taagaaagct gaccgtgttg ctgcagaagg tttgactggt gtttatgtta acggtaatgt
    19261 tgcagcagtt attgaagtaa acgctgaaac tgacttcgtt gcaaaaaacg ctcaattcgt
    19321 tgaattggta aatactacag ctaaagtcat tgctgaagga aaacctgcta acaacgaaga
    19381 agctcttgct ttgataatgc cttcaggtga aactcttgaa gctgcatacg tatctgcaac
    19441 agcaactatc ggagagaaaa tctcattccg tcgctttgca ttgattgaaa aaacagacgc
    19501 acaacacttt ggagcatacc aacataacgg tggacgtatc ggtgttattt cagttgttga
    19561 aggtggagac gaagcacttg ctaaacaatt gtcaatgcac atcgcagcga tgaaaccaac
    19621 agttctttct tacaaagaat tggatgagca attcgttaaa gatgagttgg cacaattgaa
    19681 tcacgttatc gaccaagaca acgaaagccg tgcaatggtt aataaaccag ctcttccaca
    19741 cttgaagtat ggatcaaaag ctcaattaac tgatgatgtt attgctcaag ctgaagctga
    19801 catcaaagct gaattggctg cagaaggcaa accagaaaaa atctgggaca aaattattcc
    19861 aggtaaaatg gatcgcttca tgcttgataa cactaaagtt gaccaagctt acacacttct
    19921 tgcacaagtt tacatcatgg atgacagcaa gacagttgaa gcataccttg aatcagttaa
    19981 cgcttcggta gttgagtttg ctcgctttga agttggtgaa ggtatcgaga aagctgcaaa
    20041 cgacttcgaa gctgaagttg cagctacaat ggcagcagcc ttgaataact aataatagaa
    20101 aggaagcaaa ttgcttcctt ttttgtatag ggcttagatt tttcctgaaa ttgttttttc
    20161 cccagtctca ctcgattaga ataattaaaa caaaaagccc tataataagg gctaagtgca
    20221 tttaggagac tatacttcaa attcatagta agcgcgttca taacaaggta tctatcctaa
    20281 ttccccaact tccagtatac tagataaaaa ataattatcg gagtaaaggt attgtactat
    20341 gataattcaa ctaagtgatt taggtcaagt tcaccttgtt tgtggcaaga cagatatgag
    20401 gtagggaata gactcattag cctatgtagt taaaacccac tttgaattgg attctttctc
    20461 cggtcaagtc tttctctttt gtggtgaacg taaagaccgc tttaaagccc tttactggga
    20521 tggtcaagga ttttggctac tatataaacg ctttgagaac ggaaaactga cttggctaag
    20581 tacagaaaag gatgtcaaag ctctcgcacc tgaacaagta gattggctta tgaagggctt
    20641 ttctatcact ccaaaatata gtatattgaa actagaatag tacacctctg cttctaaaac
    20701 attgttagaa atcgatttga ctgtcctgat cgatttatcc tgttcttatt tcattttact
    20761 ataaatctat cagaaagttg tgatttctat tgaaatgagg actttctttt tacactcatc
    20821 tgctttcaaa aagcattcta gtccgtctcc gattaacgat ggactttatc acctccttct
    20881 ccagtccttg tatgacatct tccaaagttc gaaaggcttt attcttaaat ccacgtttac
    20941 gaatctcttt ccacacttgt tcaatggggt tcatctctgg tgtgtatgga ggaataaatg
    21001 caaagccaat attagtcgga atctttaagg tacttgattt atgccatata gcattgtcca
    21061 taacgagtaa aagataatca tctggataag cttgtgaaat ctcctattcc taaagcccct
    21121 ttagcgcata actttggctc agcttctatt atcgctcaca ccatccatca gaagtttaat
    21181 ctgaaggtac ccaattatcg ccaagaagaa gattgggcta ggatgggttt accaatcata
    21241 cgtaaggaaa tctctaattg gcatatcaag acgagtcaat actatttgga gcccctttat
    21301 aacctcttgc gagagagact attgactcag cccttacttc atgcggatga aacttcttat
    21361 agggtgctag agagtgatag tcagctgact tactactgga cttttttgtc tgggaaagct
    21421 gagaaacaag ggattacgct ttaccatcat gtcctaatcg atttgttcat atcttatttc
    21481 aatccattat aaatagtgag aaatatctat cctatcttct agaatgtctt ccaaacgtgg
    21541 aaactctcgt aaacaaagag gttttagagg cctatttacc atggactaaa gttgtacaag
    21601 aaaagtgcaa ataagaaatc tccagattag gaactatccg tgagttctct agtctggaga
    21661 tttttcaata gacttcgtta ttggacggtt acaattcata aagtgctgta gagagataac
    21721 gttcaccgtt atctggtgct agggcaagga cttttttacc tgtacctaat tttttggcaa
    21781 cctcgatggc tccgtagata gctgcagctg aggaaatccc tacaaggaag ccttcttttc
    21841 caccaatttc acgtccgagt gcaagagcgt catctgatgt tacacgaacg ataccatcat
    21901 aggctttagt atcaagtgta tcaggaataa atccagctga gataccttga attttgtgag
    21961 gaccaggttt ttcaccagat agaatagcag attcatctgc ttctactgca aaaacttgaa
    22021 tgttagaatt ttctgatttg agtgcatgag aaacaccaga aatcgttcca ccagtaccta
    22081 ctccagcaac aaaggcatct aatccatctt taccgaaagc agctagtatc tcagctcctg
    22141 ttgttctttc gtgtacttct ggattagctg gattgtcaaa ttgaagagga aggaaaccat
    22201 cacgttcagc agcgatttct tgagccttag caatagcacc tttcattccc tcgctaccag
    22261 gagttaggac gagttcagca ccataagctt ggataatttt acgtcgttct acactcatag
    22321 tttcaggcat aacgatgacg actttatacc ctttagcagc acctacccat gaaagtccaa
    22381 taccggtgtt tccacttgtt gcttcaacaa tagtagaacc aagtttcaga ataccatctt
    22441 gttcagcttt ttcaatcatg ctaagggcaa tacggtcttt tacagatgaa ccaggattaa
    22501 atgcttcaag ctttatatag acgtctgcag caccttctgg cacgatgttg ttaagtttaa
    22561 caatcggtgt ttgaccgatt aattcagtaa tgttgttata aatagacata tgaatacctc
    22621 tttgtataag atatctttag tataacgcta tccataccat ttgtaaaata tagaaatcct
    22681 atcgaagcga taggatttct atatatcata gatcaaagtc attaattttc aagtgattgc
    22741 gttcagttaa ttctagtaaa taggtgtgaa ggaaaacgat atcaggtttc gtttgaattg
    22801 cttcattttc tagtatattt tggtacgcat ctttttattt tgctcgctaa agtagttgtg
    22861 agaatgtcaa cgaaacgctg tattattcat tgtttacact aagtttacag aaacttcaac
    22921 ctctcgtaaa ccttggtcag ttaaagtgac ttttccatta aaaaactcca caagtgcagc
    22981 tttaatagtt tctttttctt ctttatcaac ataaatcatc gtatcgactt gatctgtaaa
    23041 gtttgtatcc agctccatga gatcatgttc tttaaggaag ttactgtact cttggtactg
    23101 agcataagac atttgaatag caatgccagc ctgttctttt atttcaataa taccaatttc
    23161 tttgacagct aaggcgacac tgccggcgta agcacgaatt agtcctccag cgcctagttt
    23221 aataccacca aagtagcgtg tcacgaccac acagacattg gtgagattgt gattttctag
    23281 taccccaagc atgggaacac cagcagtacc actaggctca ccatcatcac ttgtacgttt
    23341 aatttcacta cgttctccaa taataaaggc agagcagtta tgtgtcgctt tgtagtgttc
    23401 ttttttgatg gcagtaatga agtcacgagc ctcttcttcg ctataaacac gcttggcatg
    23461 gcagataaag cgagattttt tgatttcttc ttggacttgg ccgtcctctt taattgtcct
    23521 aaattccatg atttaattgt actaaaaaat aatctaaagt gctagttttt acgaataaag
    23581 aagtatgaaa gtaaatttag attatctcgg tcgtttattt actgagaatg aattaacaga
    23641 agaagaacgt cagttggcgg agaaacttcc agcaatgaga aaggagaagg ggaaactttt
    23701 ctgtcaacgt tgtaatagta ctattctaga agaatggtat ttgcccatcg gtgcttacta
    23761 ttgtcgagag tgcttgctga tgaagcgagt cagaagtgat caaactttat actattttcc
    23821 gcaggaggat tttccgaagc aagatgttct caaatggcgc ggccaattaa ctccttttca
    23881 agagaaggtg tcagagggac tgcttcaagc agtagacaag caaaagccaa ccttagttca
    23941 tgcggtaaca ggagctggaa agacagaaat gatttatcaa gtagtggcta aagtgatcaa
    24001 tgcgggtggt gcagtgtgtt tggctagtcc tcgcatagat gtttgtttgg agctgtacaa
    24061 gcgcctgcaa caggattttt cttgcggtat agctttgcta catggagaat cggaacctta
    24121 ttttcgaaca ccactagttg ttgcaacaac ccatcagtta ttgaagtttt atcaagcttt
    24181 tgatttgctg atagtggatg aagtagatgc ttttccttat gttgataatc ccacgcttta
    24241 ccacgctgtc aagaatagtg taaaggagaa tggattgaga atctttttaa cagcgacttc
    24301 gaccaatgag ttagataaaa aggtccgttt aggagaacta aaaagactga gtttaccgag
    24361 acggtttcat ggaaatccgt tgattattcc aaaaccaatt tggttatcgg attttaatcg
    24421 ctacttagac aagaatcgtt tgtcaccaaa gttaaagtcc tatattgaga agcagagaaa
    24481 gacagcttat ccgttactca tttttgcttc agaaattaag aaaggggagc agttagaaga
    24541 aatcttacag gagcaatttc caaatgagaa aattggcttt gtatcttctg taacagagga
    24601 tcgattagag caagtacaag cttttcgaga tggagaactg acaatactta tcagtacgac
    24661 aatcttggag cgtggagtta ccttcccttg tgtggatgtt ttcgtaatag aggccaatca
    24721 tcgtttgttt accaagtcta gtttgattca gattggtgga cgagttggac gaagcatgga
    24781 tagaccgaca ggagatttgc ttttcttcca tgatgggtta aatgcttcaa tcaagaaggc
    24841 gattaaggaa attcagatga tgaataagga ggctggtcta tgaagtgctt gttatgtggg
    24901 cagactatga agactgtttt aacttttagt agtctcttac ttctgaggaa tgatgactct
    24961 tgtctttgtt cagactgtga ttctactttt gaaagaattg gggaagagaa ctgtccaaat
    25021 tgtatgaaaa cagagttgtc aacaaagtgt caagcttgtc aattttggtg taaagaagga
    25081 gttgaagtca gtcatagagc gatttttact tacaatcaag ctatgaagga ttttttcagt
    25141 cggtataagt ttgatggaga cttcctgtta agaaaagttt tcgcttcatt tttaagtgag
    25201 gagttgaaaa agtacaaaga gtatcaattt gttgtaattc ccctaagtcc tgatagatat
    25261 gctaacagag gatttaatca ggttgagggc ttggtagagg cagcaggctt tgagtatcta
    25321 gatttattag agaaaagaga agagagagcc agttcttcta aaaatcgttc agagcgcttg
    25381 gggacagaac ttcctttctt tattaaaagt ggagtcacta ttcctaaaaa aatcctactt
    25441 atagatgata tctatactac aggagcaact ataaatcgtg ttaagaaact gttggaagaa
    25501 gctggtgcta aggatgtaaa aacattttcc cttgtaagat gaggaaaaaa tttgcaaaaa
    25561 tagaatgaaa gcgttataat aaaatcataa aaacaaaaat gtttagaaag aaggtactca
    25621 tatgattaaa tatagtatcc gtggtgaaaa cctagaagta acagaagcaa ttcgtgatta
    25681 tgtagtttct aaactcgaaa agatcgaaaa gtacttccaa ccagaacaag agttggatgc
    25741 ccgaattaac ttaaaagttt atcgtgaaaa aacggctaaa gtggaagtaa cgattccgct
    25801 tggatctatt actctccgcg cagaagatgt atctcaagat atgtatggtt caattgacct
    25861 tgtaactgat aaaattgaac gtcagattcg taaaaataaa acaaaaatcg agcgtaaaaa
    25921 taaaaataag gtagcaactg gtcaattatt tacagatgct ttggtggaag attcaaatat
    25981 tgtccagtct aaagttgttc gttcaaaaca aattgattta aaaccaatgg atttggaaga
    26041 agcaattcta caaatggatt tattggggca tgatttcttt atctatgtgg atgttgaaga
    26101 tcagacaacc aatgtgattt atcgtcgtga ggatggcgaa attggtttgt tagaggttaa
    26161 agaatcttaa tttcaatatg tgtaaaggta ggtttactga attgtaaact acctttttct
    26221 tataattgat agaattactg attacacttt taaaaagtcg ctttttgagg ggtattatgg
    26281 tataatgggt gccaagaggt tttgaatgaa aaaattttat gtaagtccaa tttttcctat
    26341 tctagtagga ttgattgcgt ttggagtctt atccactttc attatttttg ttaataataa
    26401 tctgttgacg gttttaattt tgtttctttt tgtaggaggc tatgtttttt tatttaagaa
    26461 actgagagtg cattatacaa ggagtgatgt agaacagata cagtatgtaa accaccaagc
    26521 ggaagaaagt ttgacagctc tattggaaca gatgcctgta ggtgttatga aattgaattt
    26581 atcttctgga gaggttgagt ggtttaatcc ctatgctgaa ttgattttga ccaaggaaga
    26641 tggtgatttt gatttagaag ctgttcaaac gattatcaag gcttcagtag gaaatccgtc
    26701 tacttatgcc aagcttggtg agaagcgtta tgctgttcat atggatgctt cttccggtgt
    26761 tttgtatttt gtagatgtat ccagggaaca agccataaca gatgaattgg taacaagtcg
    26821 accagtgatt gggattgtct ctgtggataa ttatgatgat ttggaggatg caacttctga
    26881 gtcagatatt agtcaaatca atagttttgt agctaatttt atatcagagt tttcagaaaa
    26941 atacatgatg ttttctcgtc gggtaagtat ggatcgattt tatctattta ctgactacac
    27001 ggtgcttgag ggcttgatga atgataaatt ttctgttatt gatgctttca gagaagagtc
    27061 gaaacagaga cagttgccct tgaccttaag tatgggattt tcttatggcg atggaaatca
    27121 tgatgagata gggaaagttg ctttgctcaa tttgaacttg gctgaagtac gtggtggcga
    27181 ccaggtggtt gttaaggaaa acgacgaaac gaaaaatcca gtttattttg gtggtgggtc
    27241 tgctgcttca atcaagcgta cacggactcg tacgcgcgct atgatgacag ctatttcaga
    27301 taagattcgg agtgtagatc aggtttttgt agtcggtcac aaaaatttag acatggatgc
    27361 tttgggctct gctgtaggta tgcagttgtt cgccagcaat gtgattgaaa atagctatgc
    27421 tctttatgat gaagaacaaa tgtctccaga tattgaacga gctgtttcat tcatagaaaa
    27481 agaaggagtt acgaagttgt tgtctgttaa ggatgcattg gggatggtga ccaatcgttc
    27541 tttgttgatt cttgtagacc attcaaagac agccttaaca ttatcaaaag aattttatga
    27601 tttatttacc caaaccattg ttattgacca ccatagaagg gatcaggatt ttccagataa
    27661 tacggtcatt acttatatcg aaagtggtgc aagtagtgcc agtgagttgg taacggaatt
    27721 gattcagttc cagaattcta agaaaaatcg tttgagtcgt atgcaagcaa gtgtcttgat
    27781 ggctggtatg atgttggata ctaaaaattt cacctcgcga gtaactagtc ggacatttga
    27841 tgttgctagc tatctcagaa cgcgcggaag tgatagtatt gctatccagg aaatcgctgc
    27901 gacagatttt gaagaatatc gtgaggtcaa tgaacttatt ttacaggggc gtaaattagg
    27961 ttcagatgta ctaatagcag aggctaagga cacgaaatgc tatgatacag ttgttattag
    28021 taaggcagca gatgccatgt tagccatgtc aggtattgaa gcgagttttg ttcttgcgaa
    28081 gaatacacaa ggatttatct ctatctcagc tcgaagtcgt agtaaactga atgtacaacg
    28141 gattatggaa gagttaggcg gtggaggcca ctttaatttg gcagcagctc aaattaaaga
    28201 tgtaaccttg tcagaagcag gtgaaaaact gacagaaatt gtattaaatg aaataaagga
    28261 aaaggagaaa gaagaatgaa agtaatcttt ttagcagatg ttaaaggaaa aggtaaaaaa
    28321 ggcgaaatta aggaagtacc aacagggtat gcgcaaaact ttcttatcaa aaagaatcta
    28381 gccaaagaag cgactgctca agctgtaggt gaacttcgtg gtaaacaaaa atcggaagaa
    28441 aaagctcacg ctgagatgat tgcagaagga aaagcaatta aagcacaact tgaagcagaa
    28501 gaaactgttg tagaatttgt tgaaaaagtt ggtccagatg gtcgtacctt tggctctatt
    28561 accaataaga agattgcaga agaattgcaa aaacaatttg gaattaagat tgataaacgt
    28621 catattcaag tacaagctcc gattcgagcg gttggtttga ttgatgtgcc agtgaaaatc
    28681 tatcaagata tcacaagtgt aatcaatctt cgtgtgaaag aaggataagt ttacaccttc
    28741 ttgacaagat tgtaaaagga agggaagtct gatggcagaa gtagaagagt tacgagtaca
    28801 acctcaagat atcttagctg agcaatccgt tttaggggct atctttattg atgagagtaa
    28861 acttgttttt gtgcgagaat acattgagtc tcgggacttt tttaagtatg cccatcgttt
    28921 gattttccaa gccatggtcg atttatccga tcgtggtgat gccatagatg caacaacggt
    28981 tcgtactatc cttgataatc aaggtgattt acagaatatt ggtggcttgt cttacttggt
    29041 tgagattgtt aattctgtgc caacttctgc taatgcggag tattatgcta agattgttgc
    29101 agaaaaagca atgctacgtc gtttaattgc caagttgaca gagtctgtca accaagctta
    29161 cgaagcgtca caaccagctg atgaaattat tgctcaggca gaaaaagggc tgattgatgt
    29221 cagtgaaaat gcaaatcgaa gcgggtttaa gaacattcga gatgtgttga atctcaactt
    29281 tggaaatctg gaagctcgct cgcaacaaac gaccgatatt acaggtattg cgacaggtta
    29341 tcgtgatttg gatcatatga caacaggact tcatgaggag gagttgatta tcttagcagc
    29401 tcgtccagca gttggtaaga cagcatttgc cttgaatatc gctcagaaca ttgggactaa
    29461 gttggacaaa acggttgcta ttttttcact cgaaatgggt gcggaaagct tggtagatcg
    29521 tatgttagct gcagaaggct tagtggagtc acattctatc cgtacagggc aattgacaga
    29581 tgaggagtgg caaaaatata ctattgctca gggtaatcta gctaacgcca gtatctatat
    29641 cgatgatacg ccaggtattc ggattacaga gattcgttct cgttctcgta aattggctca
    29701 agaaactgga aatcttggtt tgattttgat agactatttg caacttatca cgggaactgg
    29761 tcgagaaaat cgtcaacaag aagtttctga aatttctcgt cagttgaaaa tactagccaa
    29821 ggaattgaag gttccagtaa tcgctctgag tcagctttct cgtggtgtag aacaacgtca
    29881 ggacaagaga ccggtcttgt ctgatattcg tgaatctggg tctattgagc aggacgctga
    29941 tatcgtagct tttctctatc gcgatgacta ctatgaacgt ggtggtgaag aagaggaggg
    30001 tatcccaaat aataaggtgg aagttattat cgagaaaaac cgtagtggag ctcgtggaac
    30061 agtggaattg attttccaaa aagaatacaa taaattttca agtatctcaa agagggaggc
    30121 ataagatgtc agatgcattt acagatgtag ccaagatgaa aaaaatcaaa gaagaaatca
    30181 aggcacatga gggacaagtc gtagaaatga ctttggagaa tggtcgtaag cgccaaaaaa
    30241 atagattggg taagctaatt gaagtttatc catctctatt tattgtggag tttggggatg
    30301 tggaaggaga taaacaagtt aatgtttacg ttgaatcctt tacttactca gatattctta
    30361 cagaaaagaa tttgattcat tatcttgact aaagtgagaa attttctcac tttttctttt
    30421 ttctccgaat aatttaggtg aaggcaatca tcgctttata ttatttttca aggaggaaga
    30481 atgaaaattt taccgtttat agcaagagga acaagttatt acttgaagat gtcagttaaa
    30541 aagcttgttc cttttttagt agtaggattg atgctagcag ctggtgatag tgtctatgcc
    30601 tattccagag gaaatggatc gattgcgcgt ggggatgatt atcctgctta ttataaaaat
    30661 gggagccagg agattgatca gtggcgcatg tattctcgtc agtgtacttc ttttgtagcc
    30721 tttcgtttga gtaatgtcaa tggttttgaa attccggcag cttatggaaa tgcgaatgaa
    30781 tggggacatc gtgctcgtcg ggaaggttat cgtgtagata atacaccgac gattggttcc
    30841 attacttggt ctactgcagg aacttatggt catgttgcct gggtgtcaaa tgtaatggga
    30901 gatcagattg agattgagga atataactat ggttatacag aatcctataa taaacgagtt
    30961 ataaaagcaa acacgatgac aggatttatt cattttaaag atttggatgg tggcagtgtt
    31021 gggaatagtc aatcctcaac ttcaacaggc ggaactcatt attttaagac caagtctgct
    31081 attaaaactg aacccctagt tagtgcaact gtgattgatt actattatcc tggagagaag
    31141 gttcattatg atcaaattct cgaaaaagac ggctacaagt ggttgagtta tactgcctat
    31201 aatggaagct atcgttatgt tcaattggag gctgtgaata aaaatcctct aggtaattct
    31261 gttctttctt caacaggtgg aactcattat tttaagacca agtctgctat caaaactgaa
    31321 cccctagtta gcggaactgt gattgattac tattatcctg gggagaaggt tcattatgat
    31381 cagatacttg aaaaagacgg ctacaagtgg ttgagttata ctgcctataa tggaagtcgt
    31441 cgctatatac agctagaggg agtgacttct tcacaaaatt atcagaatca atcaggaaat
    31501 atctctagct atggatccaa taatagttca actgtcggtt ggaagaaaat aaatggtagt
    31561 tggtatcatt tcaaatcaaa tggttctaaa tcaacaggat ggctgaaaga cggttctagc
    31621 tggtattatt tgaaattatc tggtgaaatg cagacaggat ggttaaagga gaatggctcg
    31681 tggtattatc tgggtagttc aggggcaatg aaaacaggct ggtaccaggt ctctggtaag
    31741 tggtattatt cttactcttc aggcgcctta gctgttaata cgacggtgga tggctacaga
    31801 gtaaacagtg atggagaacg agtatagaaa attggagtag gagaaatttc ctgctctttt
    31861 ctgtaagcag tttccttgac atttttctta ttttgcgcta tcatatatac atataatata
    31921 tgggagtctg tgtacagtct gagaggaagt gttaaacttc gaccgcacct gatctgggta
    31981 atgccagcgg agggaacgat acttagtcta attttgcacc ttttccatgt atggtaaagg
    32041 tttttctttt ttttaaaagg aaaacgagaa gaggaggttc ttatgaaagc aagcattgcc
    32101 ttgcaagttt tacccctagc acaggggatt gatcggatag ctgttattga tcaggtcatt
    32161 gcttatctgc aaactcaaga agtgacgatg gtagtgacac catttgaaac ggtcttggaa
    32221 ggggagtttg atgagcttat gcgcattcta aaagaagcgc tggaagtggc agggcaggag
    32281 gcagacaatg tctttgccaa tgtcaaaata aatgtaggag agattttaag tattgatgag
    32341 aaacttgaaa agtatactga gacgacacat tagtctattg ggctttctcg gagtattgtc
    32401 aatctggcag ttagcaggtt ttcttaaact tctccccaag tttatcctgc cgacacctct
    32461 tgaaattctc cagccctttg ttcgtgacag agaatttctc tggcaccata gctgggcgac
    32521 cttgagagtg gctttactgg ggctgatttt gggagttttg attgcctgtc ttatggctgt
    32581 gctcatggat agtttgactt ggctcaatga cctgatttac cctatgatgg tggtcattca
    32641 gaccattccg accattgcca tagctcctat cctggtcttg tggctgggtt atgggatttt
    32701 gcccaagatt gtcttgatta tcttaacaac aacctttccc atcatcgtta gtattttgga
    32761 cggttttagg cattgtgaca aggatatgct gactttgttt agtctgatgc gagcaaaccc
    32821 ttggcaaatc ctgtggcatt ttaaaatccc ggttagcctg ccttactttt atgcaggtct
    32881 gagggtcagt gtctcctacg cctttatcac aactgtggta tctgagtggt tgggaggttt
    32941 tgaaggtctt ggtgtttata tgattcagtc taaaaaactg tttcagtatg ataccatgtt
    33001 tgccattatt attctggtgt cgattatcag tcttttgggt atgaagctgg tcgatatcag
    33061 tgaaaaatat gtgattaaat ggaaacgtac ttaaaataga gcgtttttga aaaagaaaag
    33121 aggaaatcaa aatgaagaaa acatggaaag tgtttttaac gcttgtaaca gctcttgtag
    33181 ctgttgtgct tgtggcctgt ggtcaaggaa ctgcttctaa agacaacaaa gaggcagaac
    33241 ttaagaaggt tgactttatc ctagactgga caccaaatac caaccacaca gggctttatg
    33301 ttgccaagga aaaaggttat ttcaaagaag ctggagtgga tgttgatttg aaattgccac
    33361 cagaagaaag ttcttctgac ttggttatca acggaaaggc accatttgca gtgtatttcc
    33421 aagactacat ggctaagaaa ttggaaaaag gagcaggaat cactgccgtt gcagctattg
    33481 ttgaacacaa tacatcagga atcatctctc gtaaatctga taatgtaagc agtccaaaag
    33541 acttggttgg taagaaatat gggacatgga atgacccaac tgaacttgct atgttgaaaa
    33601 ccttggtaga atctcaaggt ggagactttg agaaggttga aaaagtacca aataacgact
    33661 caaactcaat cacaccgatt gccaatggcg tctttgatac tgcttggatt tactacggtt
    33721 gggatggtat ccttgctaaa tctcaaggtg tagatgctaa cttcatgtac ttgaaagact
    33781 atgtcaagga gtttgactac tattcaccag ttatcatcgc aaacaacgac tatctgaaag
    33841 ataacaaaga agaagctcgc aaagtcatcc aagccatcaa aaaaggctac caatatgcca
    33901 tggaacatcc agaagaagct gcagatattc tcatcaagaa tgcacctgaa ctcaaggaaa
    33961 aacgtgactt tgtcatcgaa tctcaaaaat acttgtcaaa agaatacgca agcgacaagg
    34021 aaaaatgggg tcaatttgac gcagctcgct ggaatgcttt ctataaatgg gataaagaaa
    34081 atggtatcct taaagaagac ttgacagaca aaggcttcac caacgaattt gtgaaataat
    34141 gacagaaatt agactagagc atgtcagtta tgcctatggt caggagagga ttttagagga
    34201 tatcaaccta caggtgactt caggcgaagt ggtttccatt ctaggcccaa gtggtgttgg
    34261 aaagaccacc ctctttaatc taatcgctgg gattttagaa gttcagtcag ggagaattgt
    34321 ccttgatggt gaagaaaatc ccaaggggcg cgtgagttat atgttgcaaa aggatctgct
    34381 cttggagcac aagacggtgc ttggaaatat cattctgccc ctcttgattc aaaaggtgga
    34441 taaggcagaa gctatttccc gagcggataa aattcttgcg accttccagc tgacagctgt
    34501 aagagacaag tatcctcatg aacttagcgg tgggatgcgc cagcgtgtag ccttactccg
    34561 gacctacctt tttgggcaca agctctttct cttagatgag gcctttagcg ccttggatga
    34621 gatgacaaag atggaactcc acgcttggta tcttgagatt cacaaacagt tgcagctaac
    34681 aaccctgatc atcacgcata gtattgagga ggccctcaat ctcagcgacc gtatctatat
    34741 cttgaaaaat cgccctgggc agattgtttc agaaattaaa ctagattggt ctgaagatga
    34801 ggacaaggaa gtccaaaaga ttgcctacaa acgtcaaatc ttggcagaat taggcttaga
    34861 taagtagaaa aatagggagt tggtgaagat tatcctttac cagcgccctt tttcttttaa
    34921 aaatgagaaa atttcggtat aatagtcaaa caaggtcaag gtttaaagag agaggtgggt
    34981 ttgttatgag atttaaaaat acatcggatc atattgaggc ctacatcaag gcgattttag
    35041 atcaatctgg tatcgtggag ttgcaacgga gtcagttggc agataccttt caggttgttc
    35101 ctagtcagat taactacgtg atcaagacac gctttacgga aagtagaggc tacttggttg
    35161 aaagtaagcg tggtggcgga ggctacattc gtataggacg gattgagttt tctagtcatc
    35221 atgaaatgct ccgggagctg ctttactcga ttggtgagcg agtcagtcaa gaaatttatg
    35281 aggatattct ccagcttttg gttgagcagg aattgatgac caagcaggag atgaatttgc
    35341 tagaatcagt agctttggat cgcgttttag gagaagaagc tccagttgtt cgagcaaaca
    35401 tgctacgtca ggtcatacaa gaggtagata gaaaagggaa gtaagatgaa ctattcaaaa
    35461 gcattgaatg aatgtatcga aagtgcctac atggttgctg gacattttgg agctcgttat
    35521 ctagagtcgt ggcacttgtt gattgccatg tctaatcaca gttatagtgt agcaggggca
    35581 actttaaatg attatccgta tgagatggac cgtttagaag aggtggcttt ggaactgact
    35641 gaaacggact atagccagga tgaaaccttt atggaattgc cgttctcccg tcgtttgcag
    35701 gttctttttg atgaagcaga gtatgtagcg tcagtggtcc atgctaaggt actagggaca
    35761 gagcacgtcc tctatgcgat tttgcatgat ggcaatgcct tggcgactcg tatcttggag
    35821 agggctggtt tttcttatga agacaagaaa gatcaggtca agattgctgc tcttcgtcga
    35881 aatttagaag aacgggcagg ctggactcgt gaagatctca aggctttacg ccaacgccat
    35941 cgtactgtgg ctgacaaaca aaattctatg gccaatatga tgggcatgcc gcagactcct
    36001 agtggtggtc tcgaggacta tacgcatgat ttgacagagc aagcgcgttc tggcaagtta
    36061 gaaccagtca tcggtcggga caaggaaatc tcacgtatga ttcaaatctt gagccgtaag
    36121 actaagaaca accctgtctt ggttggggat gctggtgtcg ggaaaacagc tctggtgctt
    36181 ggtcttgctc agcgtattgc cagtggtgat gtgcctgcgg aaatggctaa gatgcgcgtg
    36241 ttagaacttg atttgatgaa tgtcgttgca gggacacgct tccgtggtga ctttgaagaa
    36301 cgcatgaata atatcatcaa ggatattgaa gaagatggcc aagtcatcct ctttatcgat
    36361 gaactccaca ccatcatggg ttctggtagc gggattgatt cgactctgga tgcggccaat
    36421 atcttgaaac cagccttggc gcgtggagct ttgagaacgg ttggtgccac cactcaggaa
    36481 gaatatcaaa aacatatcga aaaagatgcg gctctttctc gtcgtttcgc taaagtgacg
    36541 attgaagaac caagtgtggc agatagtatg actattttac aaggtttgaa ggcgacttat
    36601 gagaaacatc accgtgtaca aatcacagat gaagcggttg aaacagcggt taagatggct
    36661 catcgttatt taaccagtcg tcacttgcca gactctgcta tcgacctctt ggacgaagca
    36721 gcagcaacag tgcaaaataa ggtaaagtat gtaaaagcag acgattcaga tttgagtcca
    36781 gctgataagg ccctgatgga tggcaagtgg aaacaggcag cccagctaat cgcaaaagaa
    36841 gaggaagtac ctgtctacaa agacttggtg acagagtctg atattttgac caccttgagt
    36901 cgcttgtcag gaatcccagt tcaaaaactg actcaaacgg atgctaagaa gtatctaaat
    36961 cttgaagcag aactccataa acgtgtcatc ggtcaagatc aagctgtttc aagcattagt
    37021 cgtgcgattc gccgtaatca gtcaggaatt cgcagtcaca agcgtccgat cggttccttt
    37081 atgttcctag gacccacagg tgtcggtaag accgagttgg ccaaggcttt ggcagaagtt
    37141 ctctttgatg acgaatcagc ccttatccgc tttgatatga gtgagtatat ggagaaattc
    37201 gcagccagcc gtctaaatgg agctcctcca ggctatgtgg gttacgaaga aggtggagag
    37261 ttgacagaga aggttcgcaa taaaccctat tccgttctcc tctttgatga ggtagagaag
    37321 gcccacccag atatttttaa tgttctcttg caggttctgg atgacggtgt tttgacagat
    37381 agcaagggac gcaaggtcga tttttcaaat accattatca ttatgacatc gaacctaggt
    37441 gcgactgccc ttcgtgatga taagactgtt ggttttgggg ctaaggatat tcgttttgac
    37501 caggaaaata tggaaaaacg catgtttgaa gaactgaaaa aagcttatag accggaattc
    37561 atcaaccgta ttgatgagaa ggtggtcttc catagcctat ctagtgacca tatgcaggaa
    37621 gtggtgaaga ttatggtcaa gcctttagtg gcaagtttgg ctgaaaaagg cattgacttg
    37681 aaattacaag cttcagctct gaaattgtta gcaaatcaag gatatgaccc agagatggga
    37741 gctcgcccac ttcgcagaac cctgcaaaca gaagtggagg acaagttggc agaacttctt
    37801 cttaagggag atttagtggc aggcagcaca cttaagattg gtgtcaaagc aggccagtta
    37861 aaatttgata ttgcataaaa gaataaaagt atcagcatct gaccataagt cacagtggag
    37921 tgaaactcaa tgaaaatcaa agagcaaact aggcagctag ccgcaggttg ctcaaaacac
    37981 tggtttgagg ttgcagatag agctgacgtg gtttgaagag attttcgaag agtatgaaac
    38041 taaaacctat agcttctaaa cgatccgtgg ttttcaccat tcaacacaaa attcatatgt
    38101 ttattaccct ccgtcgtatt tgtcttagag cgtgtgtagt agaaaaagag cagtcttatc
    38161 tgaaattttt attctttcaa aagagacctg tttctttttt gcatgtcaaa tccgttctag
    38221 ctggtatttg aaaaatcaaa ctaatattca atgaaaatca aagaacaaac taggcagcta
    38281 gccacaggtt gctcaaaaca ctgttttgag gttgtagata gagctgacgt agtttgaaga
    38341 gattttcgaa gagtataagc tgcaagatga atgattttct tgtattgacg ttgttgttga
    38401 caaaaagtag cggataaatg aaatccattc cattatcata gatgataggc tggtaggaaa
    38461 ttttcaaata gcatacagga aatagatgta tggagttctg gtagtagaaa gggagagaga
    38521 tgaacatttt agttgcagat gacgaggaaa tgattagaga aggaattgca gcatttctga
    38581 cagaagaggg ttatcatgtc attatggcta aggatggaca agaggtcttg gaaaaatttc
    38641 aagatctccc tatccatctc atggtattgg atttaatgat gcctaggaag agtggttttg
    38701 aagtgttaaa agaaatcaat caaaagcacg atattcctgt catcgtcttg agtgctctgg
    38761 gagatgaaac tactcagtca caggtatttg atctctatgc tgatgatcat gtgacaaaac
    38821 ctttttcttt ggtactgctt gtcaagcgta ttaaggcgct tatcagacgt tactacgtca
    38881 tagaggatat ttggcgatat caggatgtaa cagtggattt tacctcttac aaagcacatt
    38941 ataaaaatga agaaattgat ctcaaaccaa aggaattact ggtactaaag tgtttgattc
    39001 agcataaaaa tcaagtttta agtagagagc agatattgga agaaatttca aaagatgtag
    39061 ctgatttacc ttgtgatagg gtcgttgatg tctatattcg tactcttcgc aaaaaattag
    39121 ctttagattg tatcgtgact gtgaaaaatg ttgggtataa gattagctta tgataaaaaa
    39181 tcctaaatta ttaaccaagt cttttttaag aagttttgca attctaggtg gtgttggtct
    39241 agtcattcat atagctattt atttgacctt tcctttttat tatattcaac tggaggggga
    39301 aaagtttaat gagagcgcaa gagtgtttac ggagtattta aagactaaga catctgatga
    39361 aattccaagc ttactccagt cttattcaaa gtccttgacc atatctgctc accttaaaag
    39421 agatattgta gataagcgac tccctcttgt gcatgacttg gatattaaag atggaaagct
    39481 atcaaattat atcgtgatgt tagatatgtc tgttagtaca gcagatggta aacaggtaac
    39541 agtgcaattt gttcacgggg tggatgtcta caaagaagca aagaatattt tgtttttgta
    39601 tcttccatat acatttttgg ttacaattgc tttttccttt gttttttctt atttttatac
    39661 taaacgcttg ctcaatcctc ttttttacat ttcagaagtg actagtaaaa tgcaagattt
    39721 ggatgacaat attcgttttg atgaaagtag gaaagatgaa gttggtgaag ttggagaagt
    39781 tggaaaacag attaatggta tgtatgagca cttgttgaag gttattcatg agttggaaag
    39841 tcgtaatgag caaattgtaa aattgcaaaa tcaaaaggtt tcctttgtcc gtggagcatc
    39901 acatgagttg aaaacccctt tagccagtct tagaattatc ctagagaata tgcagcataa
    39961 tattggagat tacaaagatc atccaaaata tattgcaaag agtataaata agattgacca
    40021 gatgagccac ttattggaag aagtactgga gtcttctaaa ttccaagagt ggacagagtg
    40081 tcgtgagacc ttgactgtta agccagtttt agtagatatt ttatcacgtt atcaagaatt
    40141 agctcattca ataggtgtta caattgaaaa tcaattgaca gatgctacca gggtcgtcat
    40201 gagtcttagg gcattggata aggttttgac aaacctgatt agtaatgcaa ttaaatattc
    40261 agataaaaat gggcgcgtaa tcatatccga gcaagatggc tatctctcta tcaaaaatac
    40321 atgtgcgcct ctaagtgacc aagaactaga acatttattt gatatattct atcattctca
    40381 aatcgtgaca gataaggatg aaagttccgg tttgggtctt tacattgtga ataatatttt
    40441 agaaagctat caaatggact atagttttct cccttatgaa cacggtatgg aatttaagat
    40501 tagcttgtag acagattagt tttttattaa agttcatata gggttaacat aagtgtgtta
    40561 ttctttgtgt agataaaaga aaggatacta atatggtatt agcgattatt ttagtaacat
    40621 tctttattcg attgattttt ttaaagcgtt cgatagagaa tgagaaacga atccttagca
    40681 atggcgggaa agaatttgga gttgagaata caaaacgatt aactatggct catattgttt
    40741 tttatctctc ttgcttggtt gaggcaatgg tgcacaagac aatttttgat ggcatgggca
    40801 tggttggttt agtcttgctt attttttcta tgctgatgtt aatgttggtg attcacttgt
    40861 tgggagatat ttggacagtg aagcttatgc ttgtcaataa tcacaaatat gtagatcata
    40921 tcttgtttag gacagtaaaa catcctaatt actttttaaa tattcttcct gagttgattg
    40981 gcttgacctt gttgagtcat gcttatgtga cttttgtttt agtttttcca gtttatgcag
    41041 ttattttgta tcgacgaata gctgaagagg aaaagctatt acatgaagtt ataatcccaa
    41101 atggaagcat aaagagataa atacaaaatt cgatttatat acagttcata ttgaagtgat
    41161 atagtaaggt taaagaaaaa atatagaagg aaataaacat gtttgcatca aaaagcgaaa
    41221 gaaaagtaca ttattcaatt cgtaaattta gtattggagt agctagtgta gtagttgcta
    41281 gcttgttctt aggaggagta gttcatgcag aaggggttag aagtggggat acccccaagg
    41341 ttacatctag tggggatgaa gtcgagtcgc atctaaaaaa aatattgagt gagatccaaa
    41401 cacaattaga tagaaaacga catgccaaaa ctgtagcgct aattaacaag ttgcaagaca
    41461 ttaagagaac gtattcgtat aaattaaatg ttttagaaga gaagccgaaa gctgagttga
    41521 cgtcaaaaac aaaagaagag ttaaccgcag cttttgagca atttaaaaaa gatacattac
    41581 caacagaacc aggaaaaaag gtagcagaag ctgagaagaa ggttgcagaa gctgagaaaa
    41641 aagccgagga tcaaaaagaa gaagatcgtc gtaactaccc aaccaatact tacaaaacgc
    41701 ttgaacttga aattgctgag ttcgatgtga aagttaaaga agcggagctt gaactattaa
    41761 aagagaaagc taagaaacct ttaaacgagg gcacaattaa gcaagcaaaa gagaaagttg
    41821 agagtaaaaa agctgaggct acaaggttag aaaacatcaa gacagatcgt aaaaaagcag
    41881 aagaagaagc taaacgaaaa gcagcagaag aagataaagt taaagaaaaa ccagctgaac
    41941 aaccacaacc agcgccggct cctcaaccag aaaaaccagc tccaaaacca gaaaaaccag
    42001 ctccagctcc aaaaccagag aatccagctg aacaaccaaa agcagaaaaa ccagctgatc
    42061 aacaagctga agaagactat gctcgtagat cagaagaaga atataatcgc ttgactcaac
    42121 agcaaccgcc aaaaactgaa aaaccagcac aaccatctac tccaaaaaca ggctggaaac
    42181 aagaaaacgg tatgtggtac ttctacaata ctgatggttc aatggcgaca ggatggctcc
    42241 aaaacaatgg ctcatggtac tacctcaaca gcaatggcgc tatggcgaca ggatggctcc
    42301 aaaacaatgg ttcatggtac tatctaaacg ctaatggttc aatggcaaca ggatggctcc
    42361 aaaacaatgg
//
LOCUS       DAVBDR010000010        42259 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.010, whole genome shotgun sequence.
ACCESSION   DAVBDR010000010 DAVBDR010000000
VERSION     DAVBDR010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 42259)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42259)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42259
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.010"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            1..886
                     /locus_tag="VQ540_000584"
                     /pseudo
     CDS             1..886
                     /locus_tag="VQ540_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="internal stop; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(931..1572)
                     /gene="plsY"
                     /locus_tag="VQ540_000585"
     CDS             complement(931..1572)
                     /gene="plsY"
                     /locus_tag="VQ540_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HET2544439.1"
                     /translation="MITIVLLILAYLLGSIPSGLWIGQVFFQINLREHGSGNTGTTNT
                     FRILGKKAGMATFVIDFFKGTLATLLPIIFHLQGVSPLIFGLLAVIGHTFPIFAGFKG
                     GKAVATSAGVIFGFAPIFCLYLAIIFFGALYLGSMISLSSVTASIAAVIGVLLFPLFG
                     FILSNYDSLFIAIILALASLIIIRHKDNIARIKNKTENLVPWGLNLTHQDPKK"
     gene            1708..3651
                     /gene="parE"
                     /locus_tag="VQ540_000586"
     CDS             1708..3651
                     /gene="parE"
                     /locus_tag="VQ540_000586"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HET2544440.1"
                     /translation="MSKKEININNYNDDAIQVLEGLDAVRKRPGMYIGSTDGAGLHHL
                     VWEIVDNAVDEALSGFGDRIDVTINKDGSLTVQDHGRGMPTGMHAMGIPTVEVIFTIL
                     HAGGKFGQGGYKTSGGLHGVGSSVVNALSSWLEVEITRDGAVYKQRFENGGKPVTTLK
                     KIGTAPKSKTGTKVTFMPDATIFSTTDFKYNTISERLNESAFLLKNVTLSLTDKRTDE
                     AIEFHYENGVQDFVSYLNEDKEILTPVLYFEGEDNGFQVEVALQYNDGFSDNILSFVN
                     NVRTKDGGTHETGLKSAITKVMNDYARKTGLLKEKDKNLEGSDYREGLAAVLSILVPE
                     EHLQFEGQTKDKLGSPLARPVVDGIVADKLTFFLMENGELASNLIRKAIKARDAREAA
                     RKARDESRNGKKNKKDKGLLSGKLTPAQSKNPAKNELYLVEGDSAGGSAKQGRDRKFQ
                     AILPLRGKVINTAKAKMADILKNEEINTMIYTIGAGVGADFSIEDANYDKIIIMTDAD
                     TDGAHIQTLLLTFFYRYMRPLVEAGHVYIALPPLYKMSKGKGKKEEVAYAWTDGELEE
                     LRKQFGKGATLQRYKGLGEMNADQLWETTMNPETRTLIRVTIEDLARAERRVNVLMGD
                     KVEPRRKWIEDNVKFTLEEATVF"
     gene            4071..6542
                     /gene="parC"
                     /locus_tag="VQ540_000587"
     CDS             4071..6542
                     /gene="parC"
                     /locus_tag="VQ540_000587"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HET2544441.1"
                     /translation="MSNIQNMSLEDIMGERFGRYSKYIIQDRALPDIRDGLKPVQRRI
                     LYSMNKDSNTFDKSYRKSAKSVGNIMGNFHPHGDSSIYDAMVRMSQNWKNREILVEMH
                     GNNGSMDGDPPAAMRYTEARLSEIAGYLLQDIEKNTVPFAWNFDDTEKEPTVLPAAFP
                     NLLVNGSTGISAGYATDIPPHNLAEVIDAAVYMIDHPTAKIDKLMEFLPGPDFPTGAI
                     IQGRDEIKKAYETGKGRVVVRSKTEIEKLKGGKEQIVITEIPYEINKANLVKKIDDVR
                     VNNKVAGIAEVRDESDRDGLRIAIELKKDANTELVLNYLFKYTDLQINYNFNMVAIDN
                     FTPRQVGIVPILSSYIAHRREVILARSRFDKEKAEKRLHIVEGLIRVISILDEVIALI
                     RASENKADAKENLKVSYDFTEEQAEAIVTLQLYRLTNTDVVVLQEEEAELREKIAMLA
                     AIIGDERTMYNLMKKELREVKKKFATPRLSSLEDTAKAIEIDTASLIAEEDTYVSVTK
                     AGYIKRTSPRSFAASTLEEIGKRDDDRLIFVQSAKTTQHLLMFTSLGNVIYRPIHELA
                     DIRWKDIGEHLSQTITNFETNEEILYVEVLDQFDDATTYFAVTRLGQIKRVERKEFTP
                     WRTYRSKSVKYAKLKDDTDQIVAVAPIKLDDVVLVSQNGYALRFNIEEVPVVGAKAAG
                     VKAMNLKEDDVLQSGFICNTSSFYLLTQRGSLKRVSIEEILATSRAKRGLQVLRELKN
                     KPHRVFLAGAVAEQGFVGDFFSTEVDVNDQTLLVQSNKGTIYESRLQDLNLSERTSNG
                     SFISDTISDEEVFDAYLQEVVTEDK"
     gene            6674..7696
                     /locus_tag="VQ540_000588"
     CDS             6674..7696
                     /locus_tag="VQ540_000588"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HET2544442.1"
                     /translation="MTVTIDWENLGFSYMKLPYRYLAHFKNGQWDQGELTEDATLHIS
                     ESSPSLHYGQQAFEGLKAYRTKDGSVQLFRPDENAKRLQRTCDRLLMPQVPTDMFVEA
                     CKAVVRANEEYVPPYGTGGTLYLRPLLIGVGDIIGVKPAEEYIFTIFAMPVGNYFKGG
                     LVPTNFLIQDEYDRAAPNGTGAAKVGGNYAASLLPGKMAKSRHFSDVIYLDPSTHTKI
                     EEVGSANFFGITADNEFVTPLSPSILPSITKYSLLYLAEHRLGLTPIEGDVPIDNLDR
                     FVEAGACGTAAVISPIGGIQHGDDFHVFYSETEVGPVTRKLYNELTGIQFGDIEAPEG
                     WIVKVD"
     gene            7752..8456
                     /locus_tag="VQ540_000589"
     CDS             7752..8456
                     /locus_tag="VQ540_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HET2544443.1"
                     /translation="MVLSTSAILVACGKTDKEADAPTTFSYVYAVDPASLGYSIATRT
                     SRTDVIGNVIDGLMENDKYGNVAPSQKDYDLNSTGWAPSYQDPASYLNIMDPKSGSDM
                     KHLGITKGKDKDVVAKPGLDKYKKLLEDAVSETTDLEKRYEKYAKAQAWSTDSSLLMP
                     TASSGGFPVVSNVVPFSKPYSQVGIKGEPYIFKGMKLQKDIVTTKEYNEVFKKWQKEK
                     LESNSKYQKELEKYIK"
     gene            8521..9210
                     /locus_tag="VQ540_000590"
     CDS             8521..9210
                     /locus_tag="VQ540_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HET2544444.1"
                     /translation="MEWIRLIGIAIIVVGFILKFDTIATVVLAGLVTALVSGVSLVEF
                     LEILGKEFSNQRVLTIFMVTLPLVGLSETFGLKQRSIDLIRKIKGLTVGNFYTVYFFI
                     RELAGFFSIRLGGHPQFVRPLVQPMGEAAAESQLGRKLTEVEDETIKARAAANENFGN
                     FFAQNTFVGAGGVLLIGGTLDQLGYESNYAGIASTSIIVAVITLIVVGIYNYLFDKKL
                     ISKKTRGGEQK"
     gene            9207..10130
                     /locus_tag="VQ540_000591"
     CDS             9207..10130
                     /locus_tag="VQ540_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HET2544445.1"
                     /translation="MTELAKQLLELTYIVIGCQFLHTAYCSYKDKTNPVRLGTSAFWT
                     LLSITFIGGSYMPNMSIGIIVILLSLLTLFKQVRIGTLPSLDEMKANIESNRLKNKIF
                     IPVMLMAILALVLAQMIPEFSKISISLAALFATISVLVITNSHPKSLLSENNRMTQQV
                     STSGIVPQLLGALGAIFTVAGVGDVISHLISGIVPSDSRFIGVLAYVLGMVLFTMIMG
                     NAFAAFTVITAGVGVPFVFALGANPIVAGALAMTAGYCGTLLTPMAANFNALPAALMD
                     MKDQNGVIKAQAGVALVMIVIHIFLMYFLAF"
     gene            10145..10789
                     /gene="pcp"
                     /locus_tag="VQ540_000592"
     CDS             10145..10789
                     /gene="pcp"
                     /locus_tag="VQ540_000592"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HET2544446.1"
                     /translation="MKILVTGFNPFGGEKINPALEAVKLLPSEINGAEVRWVEIPTVF
                     YKSSEVLEAEILRYQPDAVLCIGQAGGRTGLTPERVAINQDDARIPDNEGNQPIDTPI
                     RIDGASAYFSSLPIKAMVQAIKKQGLPAVVSNSAGTFVCNHLMYQALYLVDKKFPNMR
                     AGFMHIPYMMEQVVNKPNTAGMSLCDIVRGIEVAIEAIVDYKDKDLQLVGGETH"
     gene            10957..11187
                     /locus_tag="VQ540_000593"
     CDS             10957..11187
                     /locus_tag="VQ540_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000037109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HET2544447.1"
                     /translation="MSKKDKKIEIQVADAKVNVGKDSFEGYTLTIGKKVIGEIAELDG
                     QFAIIKNGNVDSFYKKLEKAVEILIENYNLAK"
     gene            11237..11317
                     /locus_tag="VQ540_000594"
     tRNA            11237..11317
                     /locus_tag="VQ540_000594"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:11271..11273,aa:Tyr,seq:gta)
     gene            11327..11398
                     /locus_tag="VQ540_000595"
     tRNA            11327..11398
                     /locus_tag="VQ540_000595"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:11359..11361,aa:Gln,seq:ttg)
     gene            11560..12762
                     /gene="rpsA"
                     /locus_tag="VQ540_000596"
     CDS             11560..12762
                     /gene="rpsA"
                     /locus_tag="VQ540_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HET2544448.1"
                     /translation="MNEFEDLLNSVSQVETGDVVSAEVLTVDATQANVAISGTGVEGV
                     LTLRELTNDRDADINDFVKVGEVLDVLVLRQVVGKDTDTVTYLVSKKRLEARKAWDKL
                     VGREEEVVTVKGTRAVKGGLSVEFEGVRGFIPASMLDTRFVRNAERFVGQEFDTKIKE
                     VNAKENRFILSRREVVEAATAAARAEVFGKLAVGDVVTGKVARITSFGAFIDLGGVDG
                     LVHLTELSHERNVSPKSVVTVGEEIEVKILDLNEEEGRVSLSLKATVPGPWDGVEQKL
                     AKGDVVEGTVKRLTDFGAFVEVLPGIDGLVHVSQISHKRIENPKEALKVGQEVQVKVL
                     EVNADAERVSLSIKALEERPAQEEGQKEEKRAARPRRPRRQEKRDFELPETQTGFSMA
                     DLFGDIEL"
     gene            12848..13345
                     /locus_tag="VQ540_000597"
     CDS             12848..13345
                     /locus_tag="VQ540_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HET2544449.1"
                     /translation="MLKSEKQSRYQMLNEELSFLLEGETNVLANLSNASALIKSRFPN
                     TVFAGFYLFDGKELVLGPFQGGVSCIRIALGKGVCGEAAHFQETVIVGDVTTYLNYIS
                     CDSLAKSEIVVPMMKNGQLLGVLDLDSSEIEDYDAMDRDYLEQFVAILLEKTTWDFTM
                     FEEKS"
     gene            13345..15000
                     /gene="dnaX"
                     /locus_tag="VQ540_000598"
     CDS             13345..15000
                     /gene="dnaX"
                     /locus_tag="VQ540_000598"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HET2544450.1"
                     /translation="MYQALYRKYRSQNFSQLVGQEVVAKTLKQAVEQEKISHAYLFSG
                     PRGTGKTSVAKIFAKAMNCPNQVGGEPCNNCYICQAVTDGSLEDVIEMDAASNNGVDE
                     IREIRDKSTYAPSLARYKVYIIDEVHMLSTGAFNALLKTLEEPTQNVVFILATTELHK
                     IPATILSRVQRFEFKSIKTQDIKEHIHYILEKENISSEPEAVEIIARRAEGGMRDALS
                     ILDQALSLTQGNELTTAISEEITGTISLSALDDYVAALSQQDVPKALSCLNLLFDNGK
                     SMTRFVTDLLHYLRDLLIVQTGGENTHHSSVFVENLALPQKNLFEMIRLATVSLADIK
                     SSLQPKIYAEMMTVRLAEIKPEPALSGAVENEIATLRQEVARLKQELSNVGAVPKQVA
                     PAPSRPATGKTVYRVDRNKVQSILQEAVENPDLARQNLIRLQNAWGEVIESLGGPDKA
                     LLVGSQPVAANEHHAILAFESNFNAGQTMKRDNLNTMFGNILSQAAGFSPEILAISME
                     EWKEVRAAFSAKAKSSQTEKEVEESLIPEGFEFLADKVKVEED"
     gene            15028..15222
                     /locus_tag="VQ540_000599"
     CDS             15028..15222
                     /locus_tag="VQ540_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3272 domain-containing protein"
                     /protein_id="HET2544451.1"
                     /translation="MNKQQFIIMALFTAAETYFFNEAWMTGRYIMAAFWAILLFRNFR
                     VSYVMGKIVDVIDQHFNRKD"
     gene            15372..16142
                     /gene="sufC"
                     /locus_tag="VQ540_000600"
     CDS             15372..16142
                     /gene="sufC"
                     /locus_tag="VQ540_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000114488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HET2544452.1"
                     /translation="MSVLEIKDLHVEIEGKEILKGVNLTLKTGEIAAIMGPNGTGKST
                     LSAAIMGNPNYEVTKGEVLFDGVNILELEVDERARMGLFLAMQYPSEIPGITNAEFLR
                     AAMNAGKEDDEKISVREFITRLDEKMELLNMKEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFALLDEIDSGLDIDALKVVSKGVNAMRGEGFGAMIITHYQRLLNYITPDVVHV
                     MMEGRVVLSGGPELAARLEREGYAKLAEELGYDYKEEL"
     gene            16170..17432
                     /gene="sufD"
                     /locus_tag="VQ540_000601"
     CDS             16170..17432
                     /gene="sufD"
                     /locus_tag="VQ540_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HET2544453.1"
                     /translation="MTRENIKLFSEMHAEPSWLADLRQKAFDKIETLELPVIERVKFH
                     RWNLGDGTITENEPSANVPDFTALDHHLKLVQVGTQTVFEQTPVELAEQGVVFTDFHS
                     ALEEIPELIEEFFMSSVKYDDDKLAAYHTAYFNSGAVLYIPDNVEITEPIEGIFYQDS
                     DSNVPFNKHIMIIAGKNSKINYLERLESRGEGSAKATANITVEVIARSGAQVKFAAID
                     RLGENVTAYISRRGKLGNDASIDWAIGVMNEGNVVADFDSDLIGNGSYADLKVVALSS
                     GRQVQGIDTRVTNYGCNSIGNILQHGVILEKATLTFNGIGHIIKGAKGADAQQESRVL
                     MLSDQARSDANPILLIDENDVTAGHAASIGQVDPEDMYYLMSRGLDKATAERLVVRGF
                     LGSVIVEIPVKEVRDEMIATIEEKLSKR"
     gene            17443..18669
                     /locus_tag="VQ540_000602"
     CDS             17443..18669
                     /locus_tag="VQ540_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000887707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HET2544454.1"
                     /translation="MLDVEAIRKDFPILDQIVNDEPLVYLDNAATTQKPLVVLKAINS
                     YYEQDNANVHRGVHTLAERATASYEAARETIRKFINAGSTKEVLFTRGTTTSLNWVAR
                     FAEEILTEGDQVLISVMEHHSNIIPWQEACRKTGAELVYVYLKDGALDMEDLRAKLTD
                     KVKFVSLAHASNVLGVVNPIKEITQLAHQVGAIMVVDGAQSTPHMKIDVQDLDLDFFA
                     FSGHKMAGPTGIGVLYGKEKYLEQMSPVEFGGEMIDFVYEQSASWKELPWKFEAGTPN
                     MAGAIGLATAVDYLEKIGMDAVEAHEQELIAYVYPKLQAIEGLTIYGSQDLAQRSGVI
                     AFNLGDLHPHDLATALDYEGVAVRAGHHCAQPLLQYLEVPASARASFYIYNTKADCDK
                     LVDALQKTKEFFNGTF"
     gene            18656..19096
                     /locus_tag="VQ540_000603"
     CDS             18656..19096
                     /locus_tag="VQ540_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HET2544455.1"
                     /translation="MALSKLDSLYMAVVADHSKNPHHQGKLEDAEQISLNNPTCGDVI
                     NLSVKFDAEDRLEDIAFLNSGCTISTASASMMTDAVLGKTKQEILELATIFSEMVQGQ
                     KDERQDQLGDAAFLSGVAKFPQRIKCATLAWNALKKTIENQEKQ"
     gene            19146..20558
                     /gene="sufB"
                     /locus_tag="VQ540_000604"
     CDS             19146..20558
                     /gene="sufB"
                     /locus_tag="VQ540_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HET2544456.1"
                     /translation="MAEERVEPKPIDLGEYKFGFHDDVEPVLSTGKGLNEGVIRELSA
                     AKGEPEWMLEFRLKSYETFKKMPMQTWGADLSEIDFDDLIYYQKPSDKPARSWDDVPE
                     KIKETFERIGIPEAERAYLAGASAQYESEVVYHNMKEEFQKLGIIFTDTDSALKEYPD
                     LFKQYFAKLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDIPLQTYFRINNENIGQFE
                     RTLIIVDEGASVHYVEGCTAPTYSSNSLHAAIVEIFALDGAYMRYTTIQNWSDNVYNL
                     VTKRAKAQKDATVEWIDGNLGAKTTMKYPSVYLDGEGARGTMLSIAFANAGQHQDTGA
                     KMIHNAPHTSSSIVSKSIAKGGGKVDYRGQVTFNKNSKKSVSHIECDTIIMDDLSASD
                     TIPFNEIHNSQVALEHEAKVSKISEEQLYYLMSRGLSESEATEMIVMGFVEPFTKELP
                     MEYAVELNRLISYEMEGSVG"
     gene            complement(20789..22030)
                     /locus_tag="VQ540_000605"
     CDS             complement(20789..22030)
                     /locus_tag="VQ540_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HET2544457.1"
                     /translation="MKKIFLTLLTVSLLGGASTAVAQDFTIAAKHAIAVEANTGKILY
                     EKDATQPVEIASITKLITAYLVYEALENGSITLSTPVDISDYPYQLTTNSEASNIPME
                     ARNYTVEELLEATLVSSANSAAIALAEKIAGSEKDFIDMMRAKLLEWGIQDATVVNTT
                     GLNNETLGDNIYPGSKKDEENKLSAYDVAIVARNLIKKYPQVLEITKKPSSTFAGMTI
                     TSTNYMLEGMPAYRGGFDGLKTGTTDKAGESFVGTTVEKGMRVITVVLNADHQDNNPY
                     ARFTATSSLMDYISSTFTLRKIVQQGDAYQDSKAPVQDGKEDTVTAVAPEDIYLIERV
                     GNQSSQSVQFTPDSKAIPAPLEAGTVVGHLTYEDKDLIGQGYITTERPSFEMVADKKI
                     EKAFFLKVWWNQFVRFVNEKL"
     gene            22133..23242
                     /locus_tag="VQ540_000606"
     CDS             22133..23242
                     /locus_tag="VQ540_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HET2544458.1"
                     /translation="MFRRNKLFFWTTEILLLTIIFYLWRQMGSLINPFVSVLNTIMIP
                     FLLGGFLYYLTNPIVTFLNKVCKLNRLLGILITLCTLVWGMVIGVVYLLPILINQLSS
                     LIISSQTIYSRVQDLIIDLSNYPALQNLDVEATIQQLNLSYVDILQNILNSVSNSVGS
                     VLSALISTVLILIMTPVFLVYFLLDGHKFLPMLERTILKRDRLHIAGLLKNLNATIAR
                     YISGVSIDAIIIGCLAYIGYSIIGLKYALVFAIFSGVANLIPYVGPSIGLIPMIIANI
                     FTDPHRLLIAVIYMLVVQQVDGNILYPRIVGSVMKVHPITILVLLLLSSNIYGVVGMI
                     VAVPTYSILKEISKFLSRLYENHKIMKERERELAK"
     gene            23776..24123
                     /gene="ssrA"
                     /locus_tag="VQ540_000607"
     tmRNA           23776..24123
                     /gene="ssrA"
                     /locus_tag="VQ540_000607"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(24306..24393)
                     /locus_tag="VQ540_000608"
     tRNA            complement(24306..24393)
                     /locus_tag="VQ540_000608"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(24357..24359),aa:Ser,seq:gga)
     gene            24555..25295
                     /locus_tag="VQ540_000609"
     CDS             24555..25295
                     /locus_tag="VQ540_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HET2544459.1"
                     /translation="MLKTERKQLILEELNQHHVVSLEKLVSLLETSESTVRRDLDELE
                     AENKLRRVHGGAELPHSLQEEETIQEKSVKNLQEKKLLAQKAASLIKEKDVIFIDAGT
                     TTAFLIHELVNKNITVVTNSIHHAAQLVEKQIPTVMVGGNVKTATDASIGGVALNQIN
                     QLHFDRAFIGMNGVDDGYYTTPDMEEGAVKRAILENAKQTYVLVDSSKIGQTCFAKVA
                     PLKRAIVITSQGHELLQVIKEKTEVIEV"
     gene            25292..26203
                     /gene="pfkB"
                     /locus_tag="VQ540_000610"
     CDS             25292..26203
                     /gene="pfkB"
                     /locus_tag="VQ540_000610"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015605104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HET2544460.1"
                     /translation="MIYTVTLNPSIDYIVRLDQVKVGSVNRMDSDDKFAGGKGINVSR
                     VLKRLNIPNTATGFIGGFTGKFITDTLAEEEIETRFVQVAEDTRINVKIKADQETEIN
                     GTGPTVESVQLEELKAILSSLTAEDTVVFAGSSAKNLGNVIYKDLISLTRQTGAQVVC
                     DFEGQTLIDSLDYQPLLVKPNNHELGAIFGVKLESLDEIEKYARELLAKGAQNVIISM
                     AGDGALLVTSEGAYFAKPIKGTVKNSVGAGDSMVAGFTGEFVKSKDVVEAFKWGVACG
                     TATTFSDDLATAEFIKETYGKVEVEKR"
     gene            26200..28152
                     /locus_tag="VQ540_000611"
     CDS             26200..28152
                     /locus_tag="VQ540_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET2544461.1"
                     /translation="MKIQDLLRKDVMLLDLQATEKTAVIDEMIKNLTDHGYVTDFETF
                     KEGILAREALTSTGLGDGIAMPHSKNAAVKEATVLFAKSNKGVDYESLDGQATDLFFM
                     IAAPEGANDTHLAALAELSQYLMKDGFADKLRQATSADQVIELFDQASEKTEELVQAP
                     ANDSGDFIVAVTACTTGIAHTYMAQEALQKVAAEMGVGIKVETNGASGVGNQLTAEDI
                     RKAKAIIIAADKAVEMDRFDGKPLINRPVADGIRKTEELINLALSGDTEVYRAANGAK
                     AATASNEKQSLGGALYKHLMSGVSQMLPFVIGGGIMIALAFLIDGALGVPNENLGNLG
                     SYHELASMFMKIGGAAFGLMLPVFAGYVAYSIAEKPGLVAGFVAGAIAKEGFAFGKIP
                     YAAGGEATSTLAGVSSGFLGALVGGFIAGALVLAIKKYVKVPRSLEGAKSILLLPLLG
                     TILTGFVMLAVNIPMAAINTAMNDFLGGLGGGSAVLLGIVLGGMMAVDMGGPVNKAAY
                     VFGTGTLAATVSSGGSVAMAAVMAGGMVPPLAIFVATLLFKDKFTKEERNSGLTNIIM
                     GLSFITEGAIPFGAADPARAIPSFILGSAVAGGLVGLTGIKLMAPHGGIFVIALTSNA
                     LLYLVSVLVGAIVSGVVYGYLRKPQA"
     gene            28316..30541
                     /locus_tag="VQ540_000612"
     CDS             28316..30541
                     /locus_tag="VQ540_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HET2544462.1"
                     /translation="MLISLGIAILLIFAAFKLGAAGITLYNLIRLLVGSLAYLAIFGL
                     LIYLFFFKWIRKQEGLLSGFFTIFAGLLLIFEAYLVWKYGLDKSVLKGTMAQVVTDLT
                     GFRTTSFAGGGLIGVALYIPTAFLFSNIGTYFIGSILILVGSLLVSPWSVYDIAEFFS
                     RGFAKWWEGHERRKEERFVKQEEKARQKAEKEARLEQEETEKALLDLPPVDMETGEIL
                     TEEAVQNLPPIPEEKWVEPEIILPQAELKFPEQEDDSDDEDVQVDFSAKEALEYKLPS
                     LQLFAPDKPKDQSKEKKIVRENIKILEATFASFGIKVTVERAEIGPSVTKYEVKPAVG
                     VRVNRISNLSDDLALALAAKDVRIEAPIPGKSLIGIEVPNSDIATVSFRELWEQSQTK
                     AENFLEIPLGKAVNGTARAFDLSKMPHLLVAGSTGSGKSVAVNGIIASILMKARPDQV
                     KFMMVDPKMVELSVYNDIPHLLIPVVTNPRKASKALQKVVDEMENRYELFAKVGVRNI
                     AGFNAKVEEFNSQSEYKQIPLPFIVVIVDELADLMMVASKEVEDAIIRLGQKARAAGI
                     HMILATQRPSVDVISGLIKANVPSRVAFAVSSGTDSRTILDENGAEKLLGRGDMLFKP
                     IDENHPVRLQGSFISDDDVERIVNFIKTQADADYDESFDPGEVSENEGEFSDGDAGGD
                     PLFEEAKSLVIETQKASASMIQRRLSVGFNRATRLMEELEIAGVIGPAEGTKPRKVLQ
                     Q"
     gene            complement(30586..31014)
                     /locus_tag="VQ540_000613"
     CDS             complement(30586..31014)
                     /locus_tag="VQ540_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2544463.1"
                     /translation="MSNYRRTSKPKTEHIKKGFTVFQKTVATIASILGLITASITIMN
                     ALDNNKNIKKEPTTSQTTTIVKEIQKESPKENTSPTKETNTSQEKTQQEETPKSSVKE
                     EKKEDQKTATQDSSTPASSKPATENEKQSNAPTSENKSNQ"
     gene            31152..32294
                     /locus_tag="VQ540_000614"
     CDS             31152..32294
                     /locus_tag="VQ540_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HET2544464.1"
                     /translation="MIYFDNSATTKPYPEALETYMQVASKILGNPSSLHRLGDQATRI
                     LDASRQQIADLIGKKSDEIFFTSGGTEGDNWLIKGVAFEKAQFGKHIIVSAIEHPAVK
                     ESALWLKSQGFEVDFAPVDKKGLVDVEALAGLIRHDTILVSIMAVNNEIGSIQPIEAI
                     SEFLADKPTISFHVDAVQALAKIPTEKYLTERVDCATFSSHKFHGVRGVGFVYIKSGK
                     KITPLLTGGGQERDYRSTTENVAGIAATAKALRLSMEKLDIFRSKTGQMKAVIRQALL
                     NYPDIFVFSDEENFAPHILTFGIKGVRGEVIVHAFEDYDIFISTTSACSSKAGKPAGT
                     LIAMGVDKDKAKSAVRLSLDLENDMSQVEQFLTKLKLIYNQTRKVR"
     gene            32303..33517
                     /gene="thiI"
                     /locus_tag="VQ540_000615"
     CDS             32303..33517
                     /gene="thiI"
                     /locus_tag="VQ540_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HET2544465.1"
                     /translation="MQYSEIMIRYGELSTKGKNRMRFINKLRNNISDVLSIYTQVKVT
                     ADRDRAHAYLNGADYTAVAESLKQVFGIQNFSPVYKVEKSVEVLKSSVQEIMRDIYKE
                     GMTFKISSKRSDHNFELDSRELNQTLGGAVFEAIPNVQVQMKSPDINLQVEIREEAAY
                     LSYETIRGAGGLPVGTSGKGMLMLSGGIDSPVAGYLALKRGVDIEAVHFASPPYTSPG
                     ALKKAQDLTRKLTKFGGNIQFIEVPFTEIQEEIKAKAPEAYLMTLTRRFMMRITDRIR
                     EVRNGLVIINGESLGQVASQTLESMKAINAVTNTPIIRPVVTMDKLEIIDIAQEIDTF
                     DISIQPFEDCCTIFAPDRPKTNPKIKNAEQYEARMDVEGLVERAVAGIMITEITPQAE
                     KDEVDDLIDNLL"
     gene            33652..34476
                     /locus_tag="VQ540_000616"
     CDS             33652..34476
                     /locus_tag="VQ540_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001076725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HET2544466.1"
                     /translation="MNQSYFYLKMKEHKLKVPYTGKERRVRILLPKDYEKDTDRSYPV
                     VYFHDGQNVFNSKESFIGHSWKIIPAIKRNPDISRMIVVAIDNDGMGRMNEYAAWKFQ
                     ESPIPGQQFGGKGVEYAEFVMEVVKPFIDETYRTKADCQHTAMIGSSLGGNITQFIGL
                     EYQDQIGCLGVFSSANWLHQEAFNRYFECQKLSPDQRIFIYVGTEEADDTDKTLMDGN
                     IKQAYIDSSLCYYHDLIAGGVHLDNLVLKVQSGAIHSEIPWSENLPDCLRFFAEKW"
     gene            34498..35237
                     /locus_tag="VQ540_000617"
                     /pseudo
     CDS             34498..35237
                     /locus_tag="VQ540_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546805.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
     gene            35250..36416
                     /locus_tag="VQ540_000618"
     CDS             35250..36416
                     /locus_tag="VQ540_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001108652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HET2544467.1"
                     /translation="MNYLVISPYYPQNFQQFTIELANKGITVLGIGQESYEQLDEPLR
                     NSLTEYFRVDNLENIDEVKRAVAFLFYKHGPIGRIESHNEYWLELDATLREQFNVFGA
                     KPEDLKKTKYKSEMKKLFKKAGVPVVPGAVIKTEADVDQAVKEIGLPMIAKPDNGVGA
                     AATFKLETEDDINHFKQEWDHSTLYFFEKFVTSSEICTFDGLVDKDGKIVFSTTFDYA
                     YTPLDLMIYKMDNSYYVLKDMDPKLRKYGEAIVKEFGMKERFFHIEFFREGDDYITIE
                     YNNRPAGGFTIDVYNFAHSLDLYRGYAAIVAGEEFPASDFETQYCLATSRRANAHYVY
                     SEEDLLAKYSQQFKVKKVMPAAFAELQGDYLYMLTTPSRQEMEQMIADFGQRQE"
     gene            36924..38417
                     /locus_tag="VQ540_000619"
     CDS             36924..38417
                     /locus_tag="VQ540_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HET2544468.1"
                     /translation="MITGELKNKIDQLWEILWTEGNANPLTNIEQLTYLLFMKDLDSV
                     ELGRESDAEFLGIPYEGVFPKDKPEYRWSTFKNIGDAQEVYRLMTQEIFPFIKNLKGD
                     TDDTAFSRYMREAIFQINKPATLQKAISILDVFPTRGLDVDFDNDKQSITDIGDIYEY
                     LLSKLSTAGKNGQFRTPRHIIDMMVELMQPTIKDIISDPAMGSAGFLVSASRYLKRKK
                     DEWETNTDNINHFHNQMFHGNDTDTTMLRLGAMNMMLHGVENPQISYLDSLSQDNEEA
                     DKYTLVLANPPFKGSLDYNSTSNDLLATVKTKKTELLFLSLFLRTLKPGGRAAVIVPD
                     GVLFGSSKAHKGIRQEIVENHKLDAVISMPSGVFKPYAGVSTAILIFTKTGNGGTDKV
                     WFYDMKADGLSLDDKRQPISDNDIPDIIERFHHLEKEAERQRTDQSFFVPVAEIKEND
                     YDLSINKYKEIEYEKVEYEPTEVILKKINDLEKEIQAGLAELEKLLK"
     gene            38430..39476
                     /locus_tag="VQ540_000620"
     CDS             38430..39476
                     /locus_tag="VQ540_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000756103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HET2544469.1"
                     /translation="MKKVKLGEVLSLKKGKKATVLAEQTTLSQRYIQIDDLRNNNNLK
                     FTESLNMTEALPDDILIAWDGANAGTVGYGLSGAVGSTITVLKKNERYKEKIISDYLG
                     VFLESKSQYLREHSTGATIPHLNKNILLDLQLELLGIEEQENIICILNTIKRLITKRK
                     LQLDELNLLVKSRFNEMFGDVILNEKEWKVSKWNEILTIRNGKNQKQVEDADGKFPIY
                     GSGGIMGYAKDWIVKKNSVIIGRKGNINKPILVRENFWNVDTAFGLEPVLEKINSEYL
                     FYFCQLYNFEKLNKAVTIPSLTKSDLLNISIPLPPLALQNEFADFVALVDKSQFACEI
                     AIKVWRNSLKFSII"
     gene            39506..42202
                     /locus_tag="VQ540_000621"
                     /pseudo
     CDS             39506..42202
                     /locus_tag="VQ540_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000526318.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
BASE COUNT        12863 a         7594 c         9345 g        12457 t
ORIGIN      
        1 gattgaagga ggaaaaagag aaagaagaaa gacagaaatt attcaagaat taatgactga
       61 gttttcgtta gatcttcttc taaaagccat taaactagct cgttcgacct actactatca
      121 cttgaaacag ctagacaaaa cagataagga ccaagagctt aaagctgaaa ttcaatccat
      181 ttttatcgaa cacaagggaa attatggtta tcgtcgaatt tatttagaac taagaaatcg
      241 tgcttatctg gtaaatcata aaagagttca aggcttgatg aaagtactca atttacaagc
      301 taaaatgcga cagaaacgaa aatattcttc tcataaagga gacgttggca agaaggcaga
      361 gaatctcatt caaggccaat ttgaaggctc taaaacaatg gaaaagtgct acacagatgt
      421 gacagaattt gccattccag caagtactca aaagctttac ttatcaccag ttttagatgg
      481 ctttaacagc gaaattatcg cctataatct ttcaacttcg cccaacttag aacaagtata
      541 aacaatgttg gaacaggcat tcaaagagaa gcactacgag aatacgattc tccatagtga
      601 ccaaggctgg caatatcaac acgattctta tcatcagttc ctagagagta agggaattca
      661 agcatccatg tcacgtaagg gaaacagccc agacaatggt atgatggagt ccttctttgg
      721 gattctgaaa tcggaaatgt tttacggtta tgagaagtcg tttcagtcgc ttaagcaatt
      781 ggaacaagcc attatagact atattgatta ctacaacaat aaacgaatta agataaaact
      841 aaaaggactt agccctgtgc aatacagaac taaatccttc ggataaatta attgtctaac
      901 ttttggggtg cagttcacag aactggcatt ttatttttta ggatcttgat gggttaggtt
      961 caatccccaa gggaccaaat tttcagtttt atttttgata cgagctatat tgtccttatg
     1021 acgaatgata atcaaactag caagtgctaa gataatagcg atgaagagag agtcatagtt
     1081 actcaggata aaaccaaaaa gtggaaagag cagaaccccg ataacagccg cgatcgatgc
     1141 tgtgacacta gacagtgaaa tcatactgcc aagatagaga gctccaaaga agataatcgc
     1201 aaggtagaga cagaagatag gcgcaaatcc gaaaattact ccagcactgg ttgcgacagc
     1261 cttaccacct ttaaatcctg caaagatagg gaaggtatgg ccgataacag ccaaaagtcc
     1321 aaagatgaga ggagaaacgc cttgtagatg aaaaataatc ggaagcagcg ttgctagggt
     1381 tcctttgaaa aagtcaatca caaaggttgc cataccagct ttcttaccta aaatgcggaa
     1441 ggtattggtc gttccagtgt taccagaacc atgctcgcgt agattgattt gaaagaatac
     1501 ttgtccaatc cagagaccag atggaatcga acccagcaga taggctagga ttaataaaac
     1561 tattgtaatc atactcctat tatatcatga attgggaaag aaaagcagag aatctctgct
     1621 aaaattgtca catcggagaa agaaaaattt tgcaaaatcc ttggaaaacc tgtagaatag
     1681 taaagatgaa cgaataggag gttccttgtg tcaaaaaagg aaatcaatat taacaattat
     1741 aatgatgatg ctattcaggt gctagaaggg ttggatgcgg tccgaaaacg tccagggatg
     1801 tatattggat cgaccgatgg cgctggtctt catcacctag tttgggaaat cgttgataat
     1861 gcagtcgatg aagccttgtc tgggtttggt gatcgtatcg atgtaaccat caataaagac
     1921 ggtagtctaa cggttcaaga ccatggacgt gggatgccga caggtatgca cgctatggga
     1981 attccaactg ttgaggttat ctttaccatt cttcatgccg gagggaaatt cggtcaaggt
     2041 ggctataaga catcaggtgg acttcacgga gtgggttctt ccgttgttaa cgccctttct
     2101 agctggttag aagttgaaat tacccgtgat ggcgcagttt acaagcaacg tttcgaaaat
     2161 ggtggaaaac ctgtcacgac tttgaagaaa atcggtacag cacccaagtc taaaacaggc
     2221 accaaagtta cttttatgcc tgacgcgact atattttcta cgacagattt caagtacaat
     2281 accatttcag agcgccttaa tgaatcagcc tttctcttga aaaatgtgac cttgtcttta
     2341 acggacaagc gaacagatga agcgattgag ttccactatg agaatggagt acaagatttt
     2401 gtttcttatc tcaacgaaga taaggaaatc ttgacgccag ttctttactt tgaaggggaa
     2461 gacaatggtt ttcaagtgga agtagccctc cagtacaatg acggattctc agataacatt
     2521 ctatcctttg tcaataacgt tcgcaccaag gacggtggaa cgcacgagac aggactcaag
     2581 tctgccatta ccaaggtcat gaatgactat gcacgtaaaa caggtcttct caaggaaaaa
     2641 gataaaaacc ttgaaggttc agactatcgt gagggactag cggccgttct ttctatctta
     2701 gttcctgaag aacacttgca gtttgaagga cagaccaagg ataaactagg aagcccccta
     2761 gctcgcccag ttgtggatgg aatagtggct gataagttga cctttttcct tatggaaaat
     2821 ggggaattag cttctaacct catccgcaag gctatcaagg cccgtgatgc tcgtgaagca
     2881 gcacgtaagg cgcgtgatga gagccgaaat gggaagaaaa acaagaaaga taagggcttg
     2941 ttgtctggga aattgacccc agcccaatct aagaatcctg ctaagaatga actctatcta
     3001 gttgaggggg actctgccgg tggttctgcc aaacaaggtc gtgaccgcaa gttccaggct
     3061 attctacctc ttcgtggtaa ggttatcaat acagccaagg ccaagatggc ggatatcctc
     3121 aaaaatgaag agatcaatac catgatttat accattggtg cgggtgttgg agcagacttc
     3181 tctattgaag atgccaacta tgataagatc attatcatga ccgatgcgga taccgacggt
     3241 gcccatatcc agaccttgct cttgacattt ttctaccgtt acatgcgtcc gctagtcgag
     3301 gcaggtcatg tctatattgc cctcccacct ctttacaaga tgtccaaagg taaaggaaag
     3361 aaagaagaag tggcctacgc ttggacggac ggagaactag aagaactccg taaacagttc
     3421 ggtaaaggcg ctaccctcca acgatacaaa ggacttggtg agatgaatgc ggaccagctc
     3481 tgggaaacaa ccatgaaccc agaaacacgt accctcatcc gtgtcacaat tgaagattta
     3541 gcgcgcgccg aacgccgcgt caatgttctc atgggagata aggtagaacc acgccgtaaa
     3601 tggattgaag ataatgtcaa gtttacgcta gaagaagcga cagtgtttta atgaaagaaa
     3661 ataatatgtt agtaaactgg aaattagagt cggatgtgaa tgactatgtg aaaaagcagt
     3721 ttgaaaatct tggtttgaaa aaattgcagg attattaatg aagaatctgc tatgagtgct
     3781 tatctcaaag aggcgcttaa gggagcggct aagacacaaa ctaagactaa ttttggaaaa
     3841 ccagattttc atattgaaaa atacaaacag gatagtttgg ttacttatcg taactgaaca
     3901 cgggaggaat tcccgtaaaa tatcttttac tgcataaaaa cctactctac attctttgaa
     3961 aggagttgaa cacgccctag atactgtgtg aaaaagataa attctcttgt gagtttgctt
     4021 acttcaagaa ttttctattt tcacttggta ttttatgggc tttgtatctt atgtctaaca
     4081 ttcaaaacat gtccctggag gacatcatgg gagagcgctt tggtcgctac tccaagtaca
     4141 ttattcaaga ccgggctttg ccagatattc gtgatgggtt gaagccggtt cagcgccgta
     4201 ttctttattc tatgaataag gatagcaata cttttgacaa gagctaccgt aagtcggcca
     4261 agtcagtcgg gaacatcatg gggaatttcc acccacacgg ggattcttct atctatgatg
     4321 ccatggttcg tatgtcacag aactggaaaa atcgtgagat tctagttgaa atgcacggta
     4381 ataacggttc tatggacgga gatcctcctg cggctatgcg ttatactgag gcacgtttgt
     4441 ctgaaattgc aggttacctt cttcaggata tcgagaaaaa tacagttcct tttgcatgga
     4501 actttgacga tacggagaaa gaaccaacgg tcttgccagc agcctttcca aacctcttgg
     4561 tcaatggttc gactgggatt tcggctggtt atgccacaga cattcctccc cataatttag
     4621 ctgaggtcat agatgctgca gtttacatga ttgaccaccc aactgcaaag attgataaac
     4681 tcatggaatt cttgcctgga ccagacttcc ctacaggggc tattattcag ggtcgtgatg
     4741 aaatcaagaa agcttatgag actgggaaag ggcgcgtggt tgttcgttcc aagactgaaa
     4801 ttgaaaagct aaaaggtggt aaggaacaaa tcgttattac tgagattcct tatgaaatca
     4861 ataaggccaa tctagtcaag aaaatcgatg atgttcgtgt taataacaag gtagctggga
     4921 ttgctgaggt tcgtgatgag tctgaccgtg atggtcttcg tatcgctatc gaacttaaga
     4981 aagacgctaa tactgagctt gttctcaact acttatttaa gtacaccgac ctacaaatca
     5041 actacaactt taatatggtg gcgattgaca atttcacacc tcgtcaggtt gggattgttc
     5101 caatcctgtc tagctacatc gctcaccgtc gagaagtgat tttggcgcgt tcacgctttg
     5161 acaaagaaaa ggctgagaaa cgtctccata tcgtcgaagg tttgattcgt gtgatttcga
     5221 ttttggatga agtcattgct cttatccgtg cttctgagaa taaggcggac gccaaggaaa
     5281 acctcaaagt tagctatgat tttacggaag aacaggctga ggctatcgta actttgcaac
     5341 tgtaccgttt gaccaatacc gatgtggttg tcttgcagga agaagaagca gagcttcgtg
     5401 agaagattgc tatgctggcg gctattatcg gtgatgaaag gactatgtac aatctcatga
     5461 agaaagaact tcgtgaggtc aagaagaaat ttgcaactcc tcgtttgagt tctttagaag
     5521 acactgcgaa agcaattgag attgatacag ctagtcttat cgctgaggaa gatacctacg
     5581 tcagcgtgac caaggcaggt tacatcaagc gtaccagtcc acgttccttt gcggcttcca
     5641 ccttggaaga aattggcaag cgtgatgatg accgtttgat ttttgttcaa tctgccaaga
     5701 caacccagca cctcttgatg ttcacaagtc ttggaaatgt catctacaga ccaatccatg
     5761 agttggcaga tattcgttgg aaggacatcg gagagcatct gagccaaacc atcacaaact
     5821 ttgaaacgaa tgaagaaatc ctttatgtgg aagtactgga tcagtttgac gatgcgacaa
     5881 cctactttgc agtgactcgc cttggtcaaa tcaaacgggt agagcgaaaa gaattcactc
     5941 catggcggac ctatagatct aagtctgtca agtatgctaa gctcaaagac gatacagatc
     6001 agattgtagc agtggctccg attaaactag atgatgttgt cttggttagt caaaatggtt
     6061 atgccctgcg tttcaatatc gaagaggttc cggttgtcgg tgctaaggca gcaggtgtca
     6121 aggctatgaa tttgaaagaa gatgatgtcc tccaatctgg ctttatctgt aatacttcgt
     6181 ccttctacct cttgacccag cgtggaagct tgaaacgtgt ttctattgag gaaattctag
     6241 caaccagccg tgccaaacga ggattacaag tcttgcgtga gttgaaaaac aaaccgcatc
     6301 gtgtcttctt ggcaggagca gttgcagagc aaggatttgt tggcgatttc ttcagtacgg
     6361 aagtggatgt gaacgaccaa actctgcttg tccaatccaa taaaggaaca atctatgaaa
     6421 gccgattgca agacttgaac ttgtcagaac gcactagcaa tggaagcttc atttctgaca
     6481 cgatttcaga tgaagaagtt tttgacgctt atcttcagga agtagttact gaagataaat
     6541 aagtgaaatg aagaatcagt tctaagagct ggtttttatt ggagaaattt tctgaaaatt
     6601 acaaaatata cttgctattt tagaaaaata gtgtagaata taagaaatag gtttttagaa
     6661 taaggagtgg aatatgacag taacgattga ttgggaaaac ctcggttttt cctatatgaa
     6721 attaccttat cgctatcttg ctcatttcaa aaatggacaa tgggatcaag gagagcttac
     6781 agaggatgca actttgcata tttcagagtc ttctccaagt cttcactatg gacaacaagc
     6841 atttgaaggt ttgaaagctt atcgtactaa ggatggcagt gttcaactgt tccgtcctga
     6901 tgaaaatgct aaacgtctgc aacgtacatg tgaccgtctc ttgatgccac aagttccgac
     6961 agacatgttt gtagaagctt gtaaagcagt tgtccgtgcg aatgaagaat acgtaccacc
     7021 atacggaaca ggtggaacct tatatcttcg ccctcttttg attggtgtcg gagatattat
     7081 cggggtaaaa ccggcagaag agtacatttt caccatcttt gctatgccag ttggaaatta
     7141 ctttaaaggt ggtttggtcc caaccaactt cttgattcag gatgagtacg accgtgcagc
     7201 accaaatggt acaggtgcgg ctaaggttgg tggaaactat gctgcaagtc tcttaccagg
     7261 aaaaatggcc aagtcacgtc atttctcaga tgttatctat ctggacccat caactcatac
     7321 aaagattgaa gaagtcggat cagctaactt ctttggaatt acagctgata atgaatttgt
     7381 aacaccattg agtccatcta tcttgccatc tattaccaag tattccttgc tttatttggc
     7441 agaacatcgc ttgggattaa ctcctattga gggtgatgtt ccaattgata atcttgaccg
     7501 ttttgtagag gcaggtgcct gtggtacagc agcggttatt tctccaattg gaggtattca
     7561 acatggtgat gatttccatg tattctatag tgaaacagaa gtaggtcctg tgacgcgtaa
     7621 attatataat gaattgacgg gtattcagtt tggcgatatt gaagcgccag aaggttggat
     7681 tgtaaaagta gattaaaata aaccaaagga gattttttat gaaatagaaa aagtggctct
     7741 taacagcagg agtggtcctg agcacgtcag ctattttagt ggcttgtgga aaaactgata
     7801 aagaagcaga tgcaccgaca acattttctt atgtctatgc agtagatcca gcatcattgg
     7861 gctacagtat agcgactcga acatcgagga cagacgttat tggaaatgtt attgatggtt
     7921 tgatggaaaa tgataaatac ggcaatgttg ctccttctca aaaagactat gatttgaaca
     7981 gtacaggatg ggctccaagc tatcaagatc cagcgtctta cttgaatatt atggatccaa
     8041 aatctggttc tgacatgaaa caccttggca ttacgaaagg aaaagataag gatgttgtag
     8101 ctaaacctgg tttggataaa tataagaaat tgttagaaga tgctgtttct gagaccactg
     8161 acctagagaa gagatatgaa aaatatgcca aagctcaagc ttggtcgaca gatagttcat
     8221 tattgatgcc aacagcttca tctggtggtt ttccagttgt aagtaacgta gtaccattct
     8281 caaaaccata ctcacaagtt ggtattaagg gggaaccata tatctttaaa ggaatgaaat
     8341 tgcaaaaaga tattgttaca acaaaagaat ataacgaggt ttttaaaaaa tggcaaaaag
     8401 aaaaattgga atccaatagc aaataccaaa aagaactaga aaaatacatt aaataaggaa
     8461 tggtattgat cttgataaaa tttttaaaat actgtcattt tgaatataaa ggagtttgat
     8521 atggagtgga ttagattaat aggaatagca atcattgttg tgggttttat tttaaaattt
     8581 gatacaattg caacagtagt cttagctggt ttggttacag ctttagtttc aggtgtttct
     8641 ctcgttgaat ttttggagat tttgggaaaa gaatttagca atcagcgagt gctcacgatt
     8701 tttatggtta ccttgcctct tgtggggctg tcagaaacct ttggactcaa gcaacgatca
     8761 atcgatttga ttcgaaagat taaaggtctg acagttggaa acttctatac agtttatttc
     8821 tttattcgag agttagctgg tttcttttca attcgtctag gaggacaccc tcagtttgtc
     8881 agacctttgg ttcaacctat gggagaagca gctgcagagt ctcaattagg tagaaagtta
     8941 acagaggttg aagatgagac aataaaagcg cgtgcggctg cgaatgaaaa ttttggaaat
     9001 ttctttgctc aaaatacgtt tgtaggtgct gggggagtcc tcttgatagg gggaacatta
     9061 gatcagttag gctatgaaag caattatgca gggattgctt ctacatctat tattgttgct
     9121 gttataacac ttattgtagt ggggatttac aattatttat ttgataaaaa attgatatca
     9181 aaaaagacta ggggaggaga acaaaaatga cagagttggc aaagcaacta ttagagttga
     9241 cctatattgt gattggttgt caatttctcc atacagccta ttgtagttat aaagataaaa
     9301 caaacccagt tcgacttggg acatctgcat tttggactct attgtctatt acgtttatag
     9361 gtggttccta tatgccaaat atgagtattg gtattattgt aatcctatta tcgctgttaa
     9421 cattgtttaa gcaagtccgt atcggaacct tgccatcctt agatgaaatg aaagccaata
     9481 ttgaatctaa caggttgaaa aataaaattt ttattccagt tatgctgatg gcaatacttg
     9541 cgttggtctt agcgcaaatg attccagaat ttagcaagat ttcgattagc cttgccgcct
     9601 tgtttgctac aatttctgtt cttgtgatta ccaatagtca ccctaagagt ctgttatcag
     9661 aaaataatcg aatgactcag caagtttcaa caagtgggat tgttcctcaa ttattagggg
     9721 ctttgggggc tatttttact gtagcaggtg ttggtgatgt tatctctcat ctgattagcg
     9781 gtattgttcc ttcagatagt cgctttatag gagttttggc ttatgttctt ggaatggttc
     9841 tattcacaat gattatggga aatgcttttg cagcattcac cgttattaca gcaggtgttg
     9901 gagttccctt tgtatttgct ctgggagcta atccaattgt ggctggtgct cttgccatga
     9961 cagcaggtta ttgtgggacc ttattgaccc caatggctgc taattttaac gctctaccag
    10021 cagcattgat ggatatgaaa gatcagaatg gcgttataaa ggctcaagca ggtgttgctc
    10081 tagtaatgat tgttattcac atattcttaa tgtactttct cgcattttag taaaggaaaa
    10141 taaaatgaaa atattggtta caggttttaa tccttttgga ggtgaaaaga ttaatccagc
    10201 tttggaggct gtaaaattat taccatctga gattaatggg gctgaagttc gctgggtaga
    10261 aattccaacg gttttttata agtcgtcaga agttttagag gcagaaatat tacgatatca
    10321 accagatgct gtactttgta ttggacaagc aggcggcagg accggcttaa cacctgaacg
    10381 agtggctatt aatcaagatg atgctcgcat acctgataac gaaggcaatc aaccaattga
    10441 tacaccgatt cgtattgatg gagcatcggc ctattttagt agtttaccta tcaaagcgat
    10501 ggtacaagct atcaaaaaac agggacttcc ggcagttgta tccaatagtg caggaacctt
    10561 tgtttgcaat catttgatgt accaagctct ttatttagtg gataaaaaat tccctaatat
    10621 gagagcaggt ttcatgcata ttccatatat gatggaacaa gtagtaaata agccgaatac
    10681 tgcaggaatg agtctatgtg atattgtaag aggcatagag gtagctattg aagctattgt
    10741 agactacaaa gataaggatt tgcagttagt aggcggtgag actcactgat aacctaaaaa
    10801 ggatagtcaa ttatgcttgt ttactaacta ttaactatgc taaatcaatt gaggttgttt
    10861 acataaaact ctatatcaga gaagcctgat atagagtttt ttcttgctag ttttaggatt
    10921 ttcttgtaaa atagaaaaag tgaagagagg tatgaaatga gcaagaaaga taaaaaaatc
    10981 gaaattcaag tagcggatgc caaagttaat gttggtaaag acagttttga aggttataca
    11041 ttgactatcg gtaaaaaagt tatcggagaa attgccgaat tagacggaca atttgccatt
    11101 ataaagaatg ggaatgtcga tagtttttat aaaaaattgg aaaaagctgt ggaaattttg
    11161 attgaaaatt ataatttagc aaaataagtc ttgttttttt gaaattttca tgatataata
    11221 gtccatgttg attgtaggag agatagcgaa gaggctaaac gcggcggact gtaaatccgc
    11281 tccttcgggt tcgggggttc gaatccctct ctctccattt cattaatggg gtatagccaa
    11341 gcggtaaggc aagggacttt gactccctca tgcgttggtt cgaatccagc taccccagtt
    11401 cttaggtaat aatcaagata aaaagcaaaa tatcttaggg tattttattt ttataattga
    11461 aagacgtgaa tgatatgaac atgtccttgc gggtgcttag gaaaaaaatt ataagtatgt
    11521 caagtttaag aaaaacttga ttgttggagg attttttaga tgaacgaatt tgaagatttg
    11581 ctaaatagcg ttagtcaagt tgagactggt gatgttgtta gtgctgaagt attgacagtt
    11641 gatgcgactc aagctaacgt tgcaatctct ggaactggtg ttgaaggtgt cttgactctt
    11701 cgcgaattga caaacgatcg tgatgcagat atcaatgact ttgttaaagt aggagaagta
    11761 ttggatgttc ttgtacttcg tcaagtagtt ggtaaagata ctgatacagt tacatacctt
    11821 gtatctaaaa aacgccttga agctcgcaaa gcatgggaca aacttgttgg tcgcgaagaa
    11881 gaagttgtta ctgttaaagg aacgcgtgcc gttaaaggtg gactttcagt agaatttgaa
    11941 ggtgttcgtg gatttatccc agcttcaatg ttggatactc gtttcgtacg taacgctgag
    12001 cgttttgtag gtcaagaatt tgatactaaa atcaaagaag ttaacgctaa agaaaaccgc
    12061 ttcatccttt cacgtcgtga agttgttgaa gcagctactg cagcagctcg cgctgaagta
    12121 ttcggtaaat tggctgttgg tgatgttgta actggtaaag ttgctcgtat cacaagcttc
    12181 ggcgctttca tcgaccttgg tggtgttgac ggattggttc acttgactga attgtcacat
    12241 gaacgtaacg tatcaccaaa atcagttgta actgttggtg aagaaattga agtgaaaatc
    12301 cttgatctta acgaagaaga aggacgtgta tcactttcac ttaaagcaac agtaccagga
    12361 ccatgggatg gcgttgagca aaaattggct aaaggtgatg tagtagaagg aacagttaaa
    12421 cgtttgactg acttcggtgc atttgttgaa gtattgccag gtatcgatgg acttgttcac
    12481 gtatcacaaa tttcacacaa acggattgaa aatccaaaag aagctcttaa agttggtcaa
    12541 gaagttcaag ttaaagttct tgaagttaac gcagatgcag aacgcgtgtc actttctatt
    12601 aaagctcttg aagaacgtcc agcccaagaa gaaggacaaa aagaagaaaa acgtgctgct
    12661 cgtccacgtc gtccaagacg tcaagaaaag cgtgatttcg aacttccaga aacacaaaca
    12721 ggattttcaa tggctgattt gtttggtgat atcgaacttt aatcaaattg aaaattcaca
    12781 aaatcctttg tttactaaac aagggatttt tcttttgtct ctgctccttt tttgatataa
    12841 tagttctatg ttaaaatcag aaaaacaatc acgttatcaa atgttaaatg aagaattgtc
    12901 cttcctattg gaaggcgaaa ccaatgtttt ggctaatctt tccaacgcca gtgctcttat
    12961 aaaatcacgt tttcctaata ccgtatttgc aggcttttat ttgttcgatg gaaaggaatt
    13021 ggttttaggt cccttccaag gaggtgtttc ctgcatccgt attgcactag gcaagggtgt
    13081 ttgtggtgag gcagctcact ttcaggaaac tgttattgtt ggagatgtga cgacctatct
    13141 caactatatt tcttgtgata gtctagctaa aagtgaaatt gtggtgccga tgatgaagaa
    13201 tggtcagtta cttggagttc tggatctgga ttcttcagag attgaggatt acgatgctat
    13261 ggatcgagat tatttggaac aatttgtcgc tattttgctt gaaaagacaa catgggactt
    13321 tacgatgttt gaggaaaaat cttaatgtat caagcacttt atcgaaaata tagaagtcaa
    13381 aacttctccc agttagttgg tcaagaagtt gtggctaaga ctcttaaaca agcggtggag
    13441 caagagaaaa taagtcacgc ttatcttttt tctggtcctc gtggaacggg aaaaaccagt
    13501 gttgctaaaa tctttgccaa ggctatgaac tgtcccaatc aagtgggtgg cgaaccttgc
    13561 aataactgct atatttgtca agcagtgacg gacggtagtt tagaagatgt cattgaaatg
    13621 gatgcagctt ctaataatgg ggtagatgaa attcgcgaaa ttcgtgataa atctacctat
    13681 gcgcctagcc ttgctcgtta taaggtttat atcatagatg aggttcacat gctgtctaca
    13741 ggggctttta atgccctcct aaagacgctg gaagaaccaa cacagaatgt agtctttatt
    13801 ttggccacta ctgaattaca caagattcct gctactattc tatcccgtgt gcaacgtttt
    13861 gagtttaaat caattaagac acaggatatt aaggaacata ttcactatat cttagaaaaa
    13921 gaaaatatca gttctgaacc agaggctgtg gaaatcattg ccagacgggc ggaaggtgga
    13981 atgcgggacg ccttgtctat tttggatcaa gccctgagtt tgacacaggg aaatgagctg
    14041 acgactgcta tctctgaaga aattactggc actattagcc tatcagcctt ggatgattat
    14101 gtggcggcct tgtctcaaca ggatgttccc aaagctttgt cttgcttgaa tcttcttttt
    14161 gacaatggta agagcatgac tcgttttgtg accgatcttt tgcactattt aagagacttg
    14221 ttaattgttc aaacaggggg agaaaatact catcatagtt cagtctttgt agaaaatttg
    14281 gcacttcctc aaaaaaatct gtttgaaatg attcgcttag caacagtgag tttagcagat
    14341 attaagtcta gtttgcagcc caagatttat gctgaaatga tgaccgtccg tttggcggaa
    14401 atcaagcccg aaccagctct atcaggagcg gttgaaaatg aaattgctac gctgagacag
    14461 gaagttgccc gtctcaaaca agagctttct aatgtaggtg cggttcctaa acaagttgca
    14521 ccagctccta gtcgaccagc tacgggcaaa acagtctatc gtgtcgatcg caataaagtg
    14581 caatctatct tacaagaggc cgtcgaaaat cctgatttag cacgtcaaaa tctaattcgt
    14641 ttgcagaatg cctggggaga ggtaattgaa agtctaggtg ggccggacaa ggctctgcta
    14701 gttggttctc aaccggttgc tgccaatgaa caccatgcta ttcttgcttt tgagtctaac
    14761 ttcaatgctg gtcaaactat gaaacgagac aatctcaata ccatgtttgg caatatcctc
    14821 agtcaggcgg caggtttttc acctgagatt ttagctattt ccatggagga atggaaagaa
    14881 gttcgcgcag ccttttcagc caaagccaaa tcttctcaaa ctgaaaaaga agtagaagaa
    14941 agcctgattc cagaaggatt tgaatttttg gctgataaag tgaaggtaga ggaagactaa
    15001 agaaagattt cgtgatacaa taagtttatg aataaacaac aatttattat tatggcgctg
    15061 tttacagctg ctgagaccta ttttttcaat gaagcctgga tgactggccg ctatattatg
    15121 gcagcctttt gggcaatttt actctttaga aatttccgag tcagttatgt gatgggcaaa
    15181 atcgttgatg tcatcgatca gcattttaat aggaaagact agccctcagc ttccagacaa
    15241 aatcaaagcc ttttaggctt ttttttgtta tactagaaaa gtatatttat agaatttttg
    15301 ctctatttct ggggaaatca gacgtttttc tagtaagtac tgtaaaagtt ttgaaaaaga
    15361 aaggaactat catgtcagta ttagagatca aagatcttca cgttgagatt gaaggaaaag
    15421 aaattttaaa aggggttaac ctgaccctga aaacaggaga aattgccgct atcatgggac
    15481 caaatggtac aggtaaatcg actctttctg ccgctatcat gggaaatcca aactatgaag
    15541 taactaaagg tgaagttttg tttgatggcg taaacatcct tgagttggaa gtggatgagc
    15601 gtgcgcgtat gggacttttc cttgctatgc aatacccatc agaaatccct ggaattacca
    15661 atgctgagtt tcttcgtgcc gctatgaatg cgggtaaaga agatgatgag aagatttcag
    15721 ttcgtgagtt tattactagg ctagatgaaa aaatggaatt gctcaacatg aaagaagaaa
    15781 tggcagagcg ttacctcaac gaaggcttct ctggtggtga gaaaaaacgc aatgaaattc
    15841 ttcaactttt gatgttggag ccaacatttg ctcttttgga cgagattgac tcaggtcttg
    15901 atattgacgc tcttaaagtt gtgtctaaag gtgtcaatgc catgcgtggt gaaggttttg
    15961 gtgctatgat catcactcac taccaacgtc ttttgaacta tatcacacct gatgtggtac
    16021 acgtgatgat ggaaggtcgt gttgtccttt ctggtggtcc agaattggct gcgcgtttgg
    16081 aacgtgaagg atacgcaaaa ttagctgaag aacttggcta cgactacaag gaagaattgt
    16141 aatttcctcg tatcttttag gagaagtaaa tgactagaga aaatattaaa cttttttcag
    16201 aaatgcacgc tgaaccaagc tggttggctg atctccgtca aaaagctttt gacaagattg
    16261 agactttgga attaccagtt attgagcgtg tcaaattcca ccgttggaat ctgggtgatg
    16321 gaacgattac agaaaatgag ccatcagcaa atgttccaga tttcacagct ttagatcatc
    16381 acttgaagtt ggtgcaagta ggaactcaaa ctgttttcga acaaactcca gttgagttag
    16441 ctgaacaggg tgttgtcttc acagactttc actcagcttt agaagaaatt ccagagctga
    16501 tcgaagaatt cttcatgtca tctgttaagt atgatgatga caagttggcg gcttaccaca
    16561 cagcttactt taacagtggt gctgtactct atattccaga taacgtagaa atcacagagc
    16621 caattgaagg aattttctac caagatagcg atagcaatgt gccgtttaac aagcatatta
    16681 tgattatcgc tggtaaaaat tctaagatta attatctgga gcgtttagag tcacgcggtg
    16741 aaggaagtgc caaagcaact gctaatatca cagtagaagt gattgcacgt tcaggtgcgc
    16801 aagtcaagtt tgctgctatc gaccgtctag gtgaaaacgt cactgcctac attagccgtc
    16861 gtggtaaatt aggcaacgat gcaagtattg actgggctat cggtgtcatg aacgaaggaa
    16921 atgtcgttgc tgattttgat agtgacttga ttggtaatgg tagctatgct gacctcaagg
    16981 ttgtagctct ttcaagtggt cgtcaggtac aagggattga tactcgtgta actaactatg
    17041 gctgcaactc tatcggaaat atcctacaac atggggttat ccttgaaaaa gcaactttga
    17101 ctttcaatgg tatcggccac atcatcaagg gtgctaaggg agcagatgcc caacaagaga
    17161 gccgtgttct catgctttca gaccaagcgc gttcagatgc taacccaatt cttttgattg
    17221 atgaaaatga tgtcactgca ggacacgcag cgtctatcgg acaagttgat ccagaagaca
    17281 tgtattacct catgagtcgt ggattggata aggcaactgc agagcgtttg gttgttcgtg
    17341 gtttccttgg atctgttatc gtggagattc cagtcaagga agttcgtgat gaaatgattg
    17401 caactatcga agagaaattg tcaaaacgct aaggggaagc ctatgttaga tgtagaagcg
    17461 attcgcaagg attttccaat tttagatcag attgtcaatg atgaacctct ggtctatctg
    17521 gacaatgctg cgacgacaca aaaaccacta gtagttctga aagctattaa cagttactat
    17581 gagcaggaca atgccaatgt tcaccgtggt gtccatacct tagcggaacg agcgacagct
    17641 tcttatgaag ctgctcgtga aaccattcgt aagtttatta atgcaggctc tacaaaggaa
    17701 gttctcttta ccagaggaac gacaaccagc cttaactggg tggcacgctt tgctgaggaa
    17761 attctcactg agggagacca ggtcttgatt tcagtaatgg aacaccattc taatatcatt
    17821 ccatggcagg aagcttgtcg aaagactgga gcagagcttg tctatgtcta tcttaaagac
    17881 ggtgccttgg atatggagga tttgcgagct aaattgactg ataaggttaa atttgtttcc
    17941 ctagctcatg cctccaatgt tcttggtgtg gtcaatccga tcaaggaaat cactcaatta
    18001 gcccaccaag ttggggcaat catggtagtg gatggtgctc aatctacacc tcatatgaag
    18061 attgatgtcc aggacttgga tctggacttt ttcgcctttt cgggtcacaa gatggctggt
    18121 ccgactggta tcggtgtcct ttacggcaaa gaaaagtatc ttgagcaaat gtctccagta
    18181 gaatttggcg gcgagatgat tgattttgtc tacgagcaat ccgctagttg gaaggaattg
    18241 ccttggaaat ttgaggctgg aacgccaaat atggcaggag ctattggact tgcgactgca
    18301 gttgattatc tggaaaagat tggtatggat gccgttgaag ctcatgaaca ggaattgatt
    18361 gcgtacgtct atccaaaact gcaggcaatt gagggattga ccatttacgg ttctcaggat
    18421 ttggctcaac gttcgggtgt tattgccttt aacctaggtg atctccatcc tcacgatctt
    18481 gcgacggctc tggattatga aggagtggct gttcgtgctg gtcaccattg tgcgcaaccc
    18541 ttgcttcagt atttggaagt cccagcatca gctcgtgcaa gtttttatat ctataatacc
    18601 aaggcagatt gcgacaaact agtcgatgcc ctacaaaaga caaaggagtt tttcaatggc
    18661 actttctaaa ctagatagcc tttatatggc agtggtagca gaccattcga aaaatccaca
    18721 tcaccaaggg aagttagaag acgctgagca aatcagtctc aacaatccga cttgtgggga
    18781 tgtcatcaac ctctctgtca agtttgatgc agaggaccgt ttggaagata ttgcttttct
    18841 aaattcagga tgcacgattt caactgcttc tgctagtatg atgacagatg ccgttttagg
    18901 aaaaaccaaa caagaaattt tagaactggc gactattttt tctgaaatgg ttcaagggca
    18961 aaaagatgag cgtcaagacc aacttggaga cgcggcattc ttgtcaggtg ttgccaaatt
    19021 ccctcaaaga atcaagtgtg caaccctagc ttggaatgcc cttaagaaaa caattgaaaa
    19081 tcaagaaaaa cagtaagaca agtttctttt gtcttatgaa ttattagaaa tgaagaaagg
    19141 atattatggc tgaagaaaga gtagaaccaa aaccaattga ccttggtgaa tataaatttg
    19201 gtttccatga cgatgtagag cctgtcttat cgacaggaaa aggactcaac gaaggtgtta
    19261 ttcgtgaatt atctgctgct aagggtgagc ctgagtggat gttggagttc cgtttgaagt
    19321 cttatgaaac cttcaaaaaa atgcccatgc aaacttgggg agcagacttg tcagagattg
    19381 actttgatga cttaatctac taccaaaaac catctgacaa accagcccgt tcttgggatg
    19441 atgtacctga aaagattaaa gaaacctttg aacgtatcgg gattccagaa gctgaacgtg
    19501 cttatttagc aggggcttct gcccagtacg agtcagaagt ggtttaccac aacatgaagg
    19561 aagagttcca aaaattaggt attatcttta cagatacaga ttccgcactc aaggaatacc
    19621 cagacttatt taaacaatac tttgcgaagt tggtaccgcc gacagataac aagttggcag
    19681 ccctcaactc agcagtatgg tcgggtggaa cttttatcta cgtgccaaaa ggtgtcaagg
    19741 tagatattcc acttcaaact tatttccgta tcaataacga aaatataggt cagttcgaac
    19801 gtaccttgat tatcgttgat gagggagcaa gcgtccacta cgtagaagga tgtacagcac
    19861 caacatattc aagcaatagc ttgcacgctg ccattgtaga aatttttgct ttggacggag
    19921 cttatatgcg ttatacaact atccaaaact ggtctgataa cgtctataac ttggtaacaa
    19981 agcgtgctaa ggctcaaaag gatgccactg ttgagtggat tgatggaaac ttgggtgcca
    20041 aaacgactat gaaatatcca tctgtttatc ttgatggaga aggagcgcgt ggtaccatgc
    20101 tctctatcgc ctttgctaat gcagggcaac accaagacac gggtgctaag atgattcaca
    20161 atgctccaca taccagctcg tctattgtgt ctaaatccat cgctaaaggt ggaggaaagg
    20221 ttgactaccg tggacaagtc acctttaaca agaactctaa gaaatctgtt tcccacattg
    20281 aatgtgatac cattatcatg gatgacttgt cagcatcaga tactattcca tttaatgaaa
    20341 ttcacaactc gcaagtggct ttggaacacg aagccaaagt atctaagatt tcagaagagc
    20401 aattgtatta tctcatgagc cgtggattgt cagaatctga ggcaactgaa atgattgtca
    20461 tgggatttgt agaacccttt acaaaagaac ttccaatgga atacgcagtt gagctgaacc
    20521 gcttgattag ctatgaaatg gagggatcag ttggataaaa tttgatttta tactcttcga
    20581 aaatctcttc aaaccacgtc agcatcgcct taccgtatgt atggttactg acttcgtcag
    20641 tttcatctac aacctcaaaa cagtgttttg agcaacctgc ggctagcttc ctagtttatt
    20701 ctttgatttt gagtattaga tttactcaaa atcaaggatt ttgaagatga acttgtatca
    20761 aaaaatcgcg gtttaaaatc gcgatttttt ataatttctc gttaacaaag cggacaaact
    20821 gattccacca aacttttaag aagaaggctt tttcaatttt cttgtctgct accatttcga
    20881 aactagggcg ctctgtggtg atgtaacctt gaccaatcaa gtccttgtct tcataagtca
    20941 aatggccaac cactgttcca gcttcaagtg gtgctgggat tgctttggaa tcaggtgtga
    21001 attgaacaga ttgggaagat tgattcccaa cacgttcgat tagatagata tcctctggag
    21061 ccactgcagt tactgtatct tcttttccat cttgtacagg ggctttgcta tcttgatagg
    21121 catcgccttg ttgaacgatt ttgcgaagtg taaatgtaga agaaatataa tccattaggg
    21181 aagatgtagc tgtaaatcga gcgtaaggat tattgtcttg atgatctgca tttaaaacaa
    21241 ctgtgatgac tctcatgcct ttttcgacag tagtaccaac aaaagactct ccagccttat
    21301 ctgttgttcc tgtttttagc ccatcaaaac caccacggta agcaggcata ccttctaaca
    21361 tgtagttggt tgaagtgatt gtcatcccag caaaagtaga agaaggtttt ttggtgattt
    21421 ctaagacttg tgggtatttt ttgatgaggt tgcgagcaac gatagcgaca tcataagcac
    21481 taagcttatt ttcctcatct tttttagaac ctgggtaaat gttatcccct agagtttcat
    21541 tgttaagacc tgtcgtattg acaacagtgg catcctgaat tccccattcc aagagttttg
    21601 cccgcatcat atcgatgaaa tctttttctg agccagcaat tttctcagct agggcaatag
    21661 cggcgctgtt ggcactagat accagagttg cttcaagcaa ctcttcgaca gtataattac
    21721 gggcctccat aggaatatta ctggcttcag aatttgtcgt caattgataa ggataatcag
    21781 aaatatctac aggagtggag agggtaatac ttccgttttc caaagcttca tagaccagat
    21841 aagcagtaat caattttgtt atggaagcaa tttcgacagg ttgcgttgca tccttctcat
    21901 agagaatttt accagtattt gcctcaacag caatcgcatg tttagcggca atggtaaaat
    21961 cttgagcaac agcagtagaa gcacccccta aaagagagac agttaacaaa gttaaaaata
    22021 tttttttcat agtagtctta ttctatcata aagaaaaaaa atattcttgc tttaataatt
    22081 catctgttaa gctttttgaa aatatggtaa aataaagtga gggaggtaac tcatgtttcg
    22141 tagaaataaa ttattttttt ggaccacaga aattttactc ttaaccatca tcttttacct
    22201 atggagacag atggggtctt tgattaaccc ttttgttagc gtgcttaata caattatgat
    22261 tccattttta ttagggggct ttctttatta tttgacaaac cctattgtta ctttcttaaa
    22321 taaagtctgt aaactcaatc gtttgcttgg tattttaatt accttgtgta ctttggtctg
    22381 gggaatggtc ataggtgttg tctatctctt acctattttg attaatcagt tatctagttt
    22441 gattatatct agtcaaacta tttatagtcg agtacaagac ttaatcatag acttatctaa
    22501 ttatcctgcg ctccagaatt tggatgtaga agctacaatt cagcagttaa acttatccta
    22561 tgttgatatt cttcaaaata tcctaaatag cgtatcaaat agtgtgggga gcgtcttgtc
    22621 agctcttatc agtactgttt tgattttgat tatgactcca gtttttttgg tttatttctt
    22681 attagatgga cataaattct tgcccatgct tgaaagaacg attctaaaga gggatcgctt
    22741 gcatattgca ggcttattaa agaatttaaa tgcgacgatt gctcgctata ttagtggagt
    22801 ttcgattgac gcaatcatta taggttgttt ggcttatatt ggctatagta ttattggttt
    22861 aaaatatgct ttagtttttg ccattttttc tggtgtagcc aatttaattc cttatgtggg
    22921 gccaagtatt ggtttgattc ctatgatcat cgcaaatata ttcactgatc cccatagact
    22981 gctgattgca gtgatttata tgcttgttgt tcagcaggta gatggcaata tcttatatcc
    23041 tcgaatcgta ggaagtgtta tgaaggttca tccaatcacg attttagttt tacttttgtt
    23101 gtcaagcaat atctatggtg tagttggaat gattgtcgca gtgccaacct attctatctt
    23161 gaaagaaatt tctaagttct tatcccgttt gtatgaaaat cataaaataa tgaaagaacg
    23221 agaaagagaa ttagctaagt aaaagtcagg agaaccctga tttttcttta ctggaagtgg
    23281 cctttagatt agaagactga aaataagtta aagtcttaaa ctaattttca cagctaagaa
    23341 tagtagaagt taatctgata aaaatcgaaa aaaccagtgg aattctgtgt cagggtaagt
    23401 tccactggtt ttcatagtct attaaagttc gaatgaaacc tatttatagt agattgaaac
    23461 tagaatagta cacctctaat tctaaaacat tgttagaaat cgatttgact gtcctgatct
    23521 attcgttcta ttcttatttc attttactat attttggtgc aataagtgaa aagtagtccg
    23581 aataatataa ggattgattt tatagttttt aaactcaaat gaattgaaat aaagagagta
    23641 cgaaaattct catctgaaag tattttagaa taattctctt cgtgaatttc ttcaaaacag
    23701 atagcttcat cttaggtatg tgatttcttt ttgcattttt gagttagata aggtataatg
    23761 gttttattgt cttttggggt cgttacggat tcgacaggca ttatgaggca tattttgcga
    23821 ctcgtgtggc gacgtaaacg ctcagttaaa tataactgca aaaaataaca cttcttacgc
    23881 tctagctgcc taaaaaccag caggcgtgac ccgatttgga ttgctcgtgt tcaatgacag
    23941 gtcttattat tagcgagata cgattaagcc ttgtctagcg gtttgataag agattgatag
    24001 actcgcagtt tctagacttg agttatgtgt cgaggggctg ttaaaataat acataaccta
    24061 tggttgtaga caaatatgtt ggcaggtgtt tggacgtggg ttcgactccc accggctcca
    24121 ttattccttt gcattctttt gcattccttg gtaaaacgtt gttaaatcaa cgttttttat
    24181 ttttatcttt ggtattcctt tgcattcttt tgctaaaaag ggagtcacaa acagacccta
    24241 ttttaaaaaa aggatagaaa aaaggataca acatttgtcg catcctaaaa ataatctttt
    24301 ttccacggaa gacatgggat tcgaacccac gcacgctatt acacgcctac cgcgtttcca
    24361 acacggcctc ttaagcctct tgagtaatct tccaatactt actcaaatag tctaccataa
    24421 aggctcttat cttgcaataa aaattctaga aataagaaaa atgatagatt ttgaaagaaa
    24481 atgataaaaa atgcttgact tcaaaagaaa gtatgataga atgaatagtg taaacgataa
    24541 caggaggtga ttcggtgtta aaaacagagc ggaagcaact gattttagag gagttaaatc
    24601 aacatcatgt agtttctcta gaaaaattag ttagtttgct agaaacgtca gaatcaacgg
    24661 ttcgaagaga cttggatgag ttggaagcgg aaaacaagct tcgtcgtgtg catggtggag
    24721 cagaactccc ccactcctta caggaagaag aaaccattca agaaaaatct gtcaaaaacc
    24781 ttcaagaaaa gaagttgctg gctcagaaag cagcctctct cattaaagaa aaagatgtca
    24841 tctttatcga tgctggaaca acaactgctt ttttgattca tgaattggtc aataagaata
    24901 ttacagttgt gaccaactcc attcaccatg ccgctcagtt ggttgaaaag cagattccaa
    24961 ctgtcatggt tggaggaaac gtcaagacgg cgacagatgc tagtatcggt ggcgttgctc
    25021 ttaaccagat taaccaattg cactttgacc gtgcctttat cggaatgaat ggtgttgacg
    25081 atggctatta tacgactcct gatatggagg agggagctgt gaaaagagct attttggaga
    25141 atgccaagca gacctacgtc ttggtggatt cgtcaaaaat tggacaaact tgctttgcca
    25201 aggtagcacc actcaaacgc gctatcgtta tcactagtca agggcatgag ctcttgcagg
    25261 ttattaagga gaaaacggag gtaatagaag tatgatttat acagtcacac tcaatccatc
    25321 cattgactat atcgttcgtt tggaccaagt caaagttggt agtgtaaatc gtatggacag
    25381 tgatgataag tttgctggtg ggaaaggaat caatgtcagc cgtgtcttga aacgtttgaa
    25441 tataccaaat acagcgacgg gatttatcgg tggctttact ggtaaattta tcacagatac
    25501 tttagcagag gaagaaatcg agacacgttt tgtccaggtg gcagaagata ctcgtatcaa
    25561 tgttaaaatc aaagcagacc aagaaacaga aatcaacgga acgggtccaa ctgttgaatc
    25621 ggttcagcta gaagaattga aagctatttt atctagtctg acagcagaag atacagttgt
    25681 ctttgcaggt tcaagtgcta aaaatctagg caatgttatc tataaggatt tgatttcctt
    25741 gacgcgccag actggtgcgc aagtggtctg tgactttgaa ggacagacct taattgatag
    25801 tttggactac cagcctcttc ttgtaaaacc aaacaatcat gaacttggag cgatttttgg
    25861 ggttaaactc gaaagtttag atgaaattga gaaatacgct cgtgagttac tggctaaggg
    25921 tgctcaaaat gttattatct ctatggctgg tgatggtgcc cttcttgtca catctgaggg
    25981 agcttacttc gctaaaccaa tcaaaggaac agtcaaaaat tcagttggag ctggtgattc
    26041 tatggttgct ggattcacag gtgaatttgt caaatcaaaa gacgtagtag aagccttcaa
    26101 atggggagtg gcttgcggaa cggcaactac cttctcagat gacttggcaa cggcggaatt
    26161 tattaaagaa acatatggaa aagttgaggt agaaaaacga tgaaaattca agacctattg
    26221 agaaaagatg tcatgttgct agatttgcag gcaactgaaa aaacagctgt catcgacgag
    26281 atgattaaaa atttgacaga ccacggttat gtaacagatt ttgaaacatt taaagaagga
    26341 attttggcgc gtgaagcttt gacttctact ggtttgggtg atggaatcgc aatgcctcac
    26401 agcaaaaacg ctgctgtcaa agaagcgaca gttctatttg ctaagtcaaa taagggtgtt
    26461 gactacgaga gcttggatgg acaagcaact gacctcttct tcatgattgc agctccagaa
    26521 ggtgccaatg atactcactt ggcagccttg gcagaattgt ctcaatactt gatgaaagac
    26581 ggttttgcag acaaacttcg tcaagcaaca tctgcagacc aagttatcga actttttgac
    26641 caagcttcag aaaaaactga ggaacttgtt caagcacctg ctaatgactc tggtgacttt
    26701 atcgtagctg ttacagcttg tacaacaggt attgcccaca cttacatggc ccaagaagcc
    26761 cttcaaaaag tagctgctga aatgggggtt ggtatcaagg tcgaaaccaa cggtgctagc
    26821 ggtgttggaa atcaactaac tgcagaagat atccgtaagg ctaaagctat tatcattgca
    26881 gcagacaagg ccgttgaaat ggatcgattt gatggaaaac cattgatcaa tcgtccagtt
    26941 gctgacggta tccgtaagac agaagagcta attaacttgg ctctttcagg agatactgaa
    27001 gtctaccgtg ccgctaatgg tgccaaagct gcaacagcct ctaacgaaaa acaaagcctt
    27061 ggtggtgcct tgtacaaaca cttgatgagt ggtgtatctc aaatgttacc attcgttatc
    27121 ggtggtggta tcatgattgc ccttgccttc ttgattgacg gtgctttggg tgttccaaat
    27181 gaaaaccttg gcaatcttgg ttcttaccat gagttagctt ctatgttcat gaaaattggt
    27241 ggagctgcct ttggtttgat gcttccagtc tttgcgggtt atgttgccta ctctattgct
    27301 gaaaaaccgg gtttggtagc aggtttcgtg gctggtgcta ttgccaaaga aggttttgcc
    27361 tttggtaaaa ttccttatgc cgcaggtggt gaagcaactt caactcttgc aggtgtctca
    27421 tctggtttcc taggtgccct tgttggtgga tttatcgcag gtgccttggt tcttgccatc
    27481 aagaaatacg ttaaagttcc tcgttcactc gaaggtgcta aatcaatcct tctattgcca
    27541 cttcttggaa caatcttgac aggatttgtt atgctagctg tgaatatccc aatggctgca
    27601 atcaacactg ctatgaatga cttcctaggc ggtcttggag gaggttcagc tgtccttctt
    27661 ggtatcgtcc ttggtggaat gatggctgtt gacatgggtg gaccagttaa taaagcagct
    27721 tatgtctttg gtacaggtac gcttgcagca actgtttctt caggtggttc tgtagccatg
    27781 gcagcagtta tggctggagg aatggtgcca ccacttgcaa tctttgtcgc aactcttctt
    27841 ttcaaagata aatttactaa ggaagaacgt aactctggtt tgacaaacat catcatgggc
    27901 ttgtcattta tcactgaggg agcgattcca tttggtgccg ctgacccagc tcgtgcgatt
    27961 ccaagcttca tccttggttc agcagtagca ggtggactcg ttggtcttac tggtatcaaa
    28021 ctcatggcgc cacacggagg aatcttcgtt atcgccctta cttcaaatgc tctcctttac
    28081 ctcgtttctg tcttggtagg agcaatcgta agtggtgtgg tttatggtta cctacgcaaa
    28141 ccacaagcat aaaaaataga aaaatgaaaa gattggaccg tttggtgcag tctttttctc
    28201 ttcccgaaat gcctgtgaaa tatggtataa tagaagaatg gcaaacaaga atacaagtac
    28261 aacaagacgg agaccgtcta aagcagaact ggaaagaaaa gaagcgattc aacgaatgtt
    28321 gatttcgtta ggaattgcga ttttattgat tttcgcagcc ttcaaattag gggctgcagg
    28381 tataaccctt tataatttaa ttcgcttgct agtgggtagc ctagcttatc tggcgatatt
    28441 cggcctatta atctatctct tctttttcaa gtggatacga aaacaggaag gactcttatc
    28501 tggctttttc accatatttg ctggcttact cttgattttt gaggcctact tggtttggaa
    28561 atatggtttg gacaagtccg ttctaaaagg gaccatggct caggttgtga cagatctgac
    28621 tggttttcga acgactagct ttgctggagg gggcttgatc ggggtcgctc tttatattcc
    28681 aacagccttt ctcttttcaa atatcggaac ttactttatt ggttctatct tgattttagt
    28741 gggttctctc ctagtcagcc cttggtctgt ttacgatatt gctgaatttt tcagtagagg
    28801 ctttgccaaa tggtgggaag ggcacgagcg tcgaaaagag gaacgctttg tcaaacaaga
    28861 agaaaaagct cgccaaaagg ctgagaaaga ggctagatta gaacaagaag agactgaaaa
    28921 agccttactc gatttgcctc ctgttgatat ggaaacgggt gaaattctga cagaggaagc
    28981 tgttcaaaat cttccaccta ttccagaaga aaagtgggtg gaaccagaaa tcatcctgcc
    29041 tcaagctgaa cttaaattcc ctgaacagga agatgactca gatgacgaag atgttcaggt
    29101 cgatttttca gccaaagaag cccttgaata caaacttcca agcttacaac tctttgcacc
    29161 agataaacca aaagatcagt ctaaagagaa gaaaattgtc agagaaaata tcaaaatctt
    29221 agaagcaacc tttgctagct ttggtattaa ggtaacagtt gaacgggccg aaattgggcc
    29281 atcagtgacc aagtatgaag tcaagccggc tgttggtgta agggtcaacc gcatttccaa
    29341 tctatcagat gacctcgctc tagccttggc tgccaaagat gtccggattg aagcaccaat
    29401 ccctgggaaa tccctaatcg gaattgaagt gcccaactcc gatattgcca ctgtatcttt
    29461 ccgagaacta tgggaacaat cgcaaacgaa agcagaaaat ttcttggaaa ttcctttagg
    29521 gaaggctgtt aatggaaccg caagagcttt tgacctttct aaaatgcccc acttgctagt
    29581 tgcaggttca acgggttcag ggaagtcagt agcagttaac ggcattattg ctagcattct
    29641 catgaaggcg agaccagatc aagttaaatt tatgatggtc gatcccaaga tggttgagtt
    29701 atctgtttac aatgatattc cccacctctt gattccagtc gtgaccaatc cacgcaaagc
    29761 cagcaaggct ctgcaaaagg ttgtggatga aatggaaaac cgttatgaac tctttgccaa
    29821 ggtgggagtt cggaatattg caggttttaa tgccaaggta gaagagttca attcccagtc
    29881 tgagtacaag caaattccgc taccattcat tgtcgtgatt gtggatgagt tggctgacct
    29941 catgatggtg gccagcaagg aagtggaaga tgctatcatc cgtcttgggc agaaggcgcg
    30001 tgctgcaggt atccacatga ttcttgcaac tcagcgtcca tctgttgatg tcatctctgg
    30061 tttgattaag gccaatgttc catctcgtgt agcatttgcg gtttcatcag gaacagactc
    30121 ccgtacgatt ttggatgaaa atggagcaga aaaacttctt ggtcgaggag acatgctctt
    30181 taaaccgatt gatgaaaatc atccagttcg tctccaaggc tcctttatct cggatgacga
    30241 tgttgagcgc attgtgaact tcatcaagac tcaggcagat gcagactacg atgagagttt
    30301 tgatccaggt gaggtttctg aaaatgaagg agaattttcg gatggagatg ctggtggtga
    30361 tccgcttttt gaagaagcta agtctttggt tatcgaaaca cagaaagcca gtgcgtctat
    30421 gattcagcgt cgtttatcag ttggatttaa ccgtgcgacc cgtctcatgg aagaactgga
    30481 gatagcaggt gtcatcggtc cagctgaagg taccaaacct cgaaaagtgt tacaacaata
    30541 aaaaaatagc ttctttccaa gtttggaggg aagctatttt agtggctatt gattgctttt
    30601 attttctgaa gttggcgcat tggactgttt ttcgttttca gtagcaggtt tacttgaagc
    30661 aggagtagaa gagtcctgag ttgctgtttt ctgatcttct tttttctctt ccttgacgct
    30721 agattttggt gtttcctctt gctgtgtttt ttcttgacta gtgttagtct ctttagttgg
    30781 actggtgttt tccttagggg attccttttg gatttctttg acaatggttg tcgtctggct
    30841 tgtcgtaggt tcttttttaa tatttttgtt attatccaag gcgttcataa tcgtgatact
    30901 tgcggtaatc aagccaagga tactagcgat tgtagcaacg gttttttgaa agactgtaaa
    30961 gccttttttg atgtgttctg tttttggttt tgaagttcta cgatagttag acatacattc
    31021 tctcctttga ttatgattta ttatactctg tttctttaaa aaaatcttaa aaaaagagaa
    31081 atttcccttt cttgtcgcaa gctccgtttc atgatacaat agaggaagtg attttagaaa
    31141 gcgtgagaaa catgatttac tttgataatt cagcgacgac caagccttat cctgaagccc
    31201 ttgaaaccta tatgcaggtc gcttcaaaaa ttttaggaaa cccatctagt ctccatcgtt
    31261 tgggagacca agcaacacga atcttagatg cttctcgcca acagattgca gatttaatcg
    31321 gtaagaaaag cgatgaaatc ttctttacct cgggtggaac agaaggggat aactggctta
    31381 tcaagggtgt ggcctttgaa aaagctcagt ttggcaagca catcattgtt tcagccattg
    31441 aacatccagc agtcaaagag tcagccctct ggttgaaaag tcaaggattt gaagtggatt
    31501 ttgctccagt tgataagaaa ggcttggtcg atgttgaggc gttagcaggt ttgatacggc
    31561 atgatacaat cctcgtttcc atcatggctg tgaacaatga aatcggctct atccaaccta
    31621 ttgaggctat ttcagaattc ttggcagaca agccgactat ttccttccac gttgatgcgg
    31681 ttcaggcgct tgccaaaatt ccgactgaaa agtatctgac agaacgggtg gattgcgcga
    31741 ctttctctag tcacaagttc cacggggttc gaggtgttgg ctttgtctat atcaaatctg
    31801 gcaagaagat tacacctctt cttacaggtg gtggccagga gcgagattat cgttcgacaa
    31861 ctgaaaatgt ggcagggatt gcagcgacag ccaaggccct ccgtttgtct atggaaaagc
    31921 tagatatctt taggagcaag actgggcaga tgaaggcagt gattcgccaa gctcttctga
    31981 actatccgga tatttttgtc ttttcagatg aggaaaactt tgcacctcat attctgactt
    32041 ttggaatcaa aggtgttcga ggtgaagtca tcgttcacgc ctttgaagac tatgatattt
    32101 tcatctcaac aacctcagct tgttcatcta aggcaggaaa accagccggt accttgattg
    32161 ccatgggagt ggacaaagat aaggccaagt cagctgtgcg tcttagccta gacttggaaa
    32221 atgatatgag tcaggtcgag cagtttttga ccaagttaaa attgatttac aatcaaacta
    32281 gaaaagtaag ataggagcat tcatgcagta ttcagaaatt atgattcgct acggagagtt
    32341 gtcaaccaag ggtaaaaacc gtatgcgttt catcaataaa cttcgtaata atatttcgga
    32401 cgttttgtct atctataccc aagttaaggt aacagcagat cgcgaccgtg cccacgctta
    32461 cctcaatgga gctgattaca cagcagttgc agaatctctc aaacaagttt ttggaattca
    32521 aaacttttct cctgtttata aggttgaaaa atctgtagaa gttttgaagt cttctgtcca
    32581 agagattatg cgggacatct acaaggaagg tatgaccttt aagatttcta gcaagcgtag
    32641 cgaccacaac tttgaacttg atagtcgtga actcaaccaa acacttggag gggctgtatt
    32701 cgaagccatt ccaaatgtgc aagttcaaat gaaaagtcct gacatcaatc ttcaggtgga
    32761 gattcgtgaa gaagcagcct atctttctta tgaaaccatt cgtggggctg gtggtttgcc
    32821 agttggaact tcaggtaaag ggatgctcat gttgtcagga gggattgact cacctgtagc
    32881 aggttatctt gctcttaagc gtggggtgga tatcgaggca gttcactttg ctagtccacc
    32941 atatactagt cctggtgccc tcaagaaagc gcaggacttg acccgtaaat tgaccaagtt
    33001 tggcggaaat atccagttta tagaggtgcc tttcacagag attcaagagg aaatcaaagc
    33061 caaagcgcca gaagcttatt tgatgactct aactcgtcgc tttatgatgc ggattactga
    33121 ccgtattcgt gaggtacgaa atggtttggt tatcatcaat ggggaaagtc taggtcaagt
    33181 agccagccaa acccttgaaa gtatgaaggc tatcaatgct gttaccaaca ctcccatcat
    33241 tcgtcctgtg gttaccatgg acaagttgga aatcattgac atcgcccagg aaatcgatac
    33301 ctttgacatt tcaatccaac cgtttgaaga ctgttgtacc atttttgcac cagatcgtcc
    33361 aaaaacaaat cctaaaatta agaatgcgga gcagtacgaa gcgcgtatgg atgttgaagg
    33421 cttggttgag cgagcagtgg ctggaatcat gattactgaa atcacacctc aagccgaaaa
    33481 agatgaagtt gatgacttga ttgacaatct gctctaattc agaaaatcca aaagaatagc
    33541 gaaaatcagt aaaaaaagtt agttttttct ctaaaaacag gtaaaaaact aacttttttt
    33601 atttttatga tataatgata taaaattttg aatatagaga gttttctgac aatgaatcaa
    33661 tcctactttt atctaaaaat gaaagaacac aaactcaagg ttccttatac aggtaaggag
    33721 cgccgtgtac gtattcttct tcctaaagat tatgagaaag atacagaccg ttcctatcct
    33781 gttgtatact ttcatgacgg gcaaaatgtt tttaatagca aagagtcttt cattggacat
    33841 tcatggaaga ttatcccagc tatcaaacga aatccggata tcagtcgcat gattgtcgtt
    33901 gctattgaca atgatggtat ggggcggatg aatgagtatg cggcttggaa gttccaagaa
    33961 tctcctatcc cagggcagca gtttggtggt aagggtgtgg agtatgctga gtttgtcatg
    34021 gaggtggtca agccttttat cgatgagacc tatcgtacaa aagcagactg ccagcatacg
    34081 gctatgattg gttcctcact aggaggcaat attacccagt ttatcggttt ggaataccaa
    34141 gaccaaattg gttgcttggg cgttttttca tctgcaaact ggctccacca agaagccttt
    34201 aaccgctatt tcgagtgcca gaaactatcg cctgaccagc gcatcttcat ctatgtagga
    34261 acagaagaag cagatgatac agacaagacc ttgatggatg gcaatatcaa acaagcctat
    34321 atcgactcgt cgctttgcta ttaccatgat ttgatagcag ggggagtaca tctggataat
    34381 cttgtgctaa aagttcagtc tggtgccatc catagtgaaa tcccttggtc agaaaatcta
    34441 ccagattgtc tgagattttt tgcagaaaaa tggtaagtta agaaaggaaa aaacgaaatg
    34501 catattgaac atcttagcca ctggagtggt catcttaacc gtgaaatgta ccttaaccgt
    34561 tatggacatg gtgggattcc agttgtggtc tttgcttcat caggtggtag tcacaacgaa
    34621 tactatgatt ttggcatgat tgatgcctgt gcttccttta tcgaggaagg ccttgtccag
    34681 ttctttaccc tatctagttt ggatagtgag agctggttgg ctacttggaa aaatgctcat
    34741 gaccaagcgg aaatgcaccg tgcctacgaa cgttatgtga ttgaggaggc cattctttta
    34801 tcaagcacaa gacaggttgg tttgatggca tgatgacgac aggttgctct atgggagcct
    34861 atcatgcact caatttcttc ctccagcatc cagatgtctt taccaaagtg attgctctca
    34921 gtggtgttta cgacgcacgt ttctttgtcg gtgattacta caacgatgat gctatttacc
    34981 aaaactcgcc agtagattat atttggaacc aaaacgacgg ctggtttatt gaccgttacc
    35041 gtcaggcaga gattgtgctg tgtacggggc ttggagcctg ggaacaagat ggtttgccat
    35101 ccttttacaa gctcaaagaa gcctttgaca agaaacaaat tccagcctgg tttgctgaat
    35161 ggggacatga tgtcgcccat gactgggaat ggtggcgtaa acaaatgcct tatttcctcg
    35221 gtaatctcta tttataaaag gagttaccta tgaattacct tgttatttct ccctactatc
    35281 cacaaaactt tcaacagttt accatcgaac tagctaataa aggcatcaca gtcttgggaa
    35341 ttggtcaaga gtcttacgag caattggatg agcccttgcg caatagcttg accgagtatt
    35401 ttcgtgttga taatcttgag aacatagatg aagtcaaacg tgcagttgct tttctctttt
    35461 ataaacatgg tccaattggc cgcatcgagt ctcacaatga atactggctt gagctagacg
    35521 caacactcag agaacaattc aatgtttttg gtgccaaacc agaggatctc aaaaagacga
    35581 aatataagtc tgaaatgaag aaacttttca aaaaagcagg tgttcctgtg gtacctggag
    35641 ctgttatcaa gacggaagca gatgttgatc aagcagtgaa agaaatcggt cttccaatga
    35701 ttgccaaacc tgataatgga gtgggagcag ccgcaacctt taaacttgag acagaagacg
    35761 atatcaatca cttcaagcaa gaatgggacc attcaaccct ttatttcttt gaaaaatttg
    35821 tcacttccag cgaaatctgt acctttgacg ggctcgtgga caaggatgga aagattgtct
    35881 tctcaacaac ctttgactac gcctatacac cgcttgacct catgatttat aagatggaca
    35941 attcttatta tgtgctcaag gatatggatc ctaaactgcg caagtatggg gaagcaattg
    36001 tcaaagaatt tggtatgaaa gaacggtttt tccatattga gttcttccgt gagggggacg
    36061 attatattac catcgagtac aataaccgcc ctgcaggtgg ttttaccatt gatgtttata
    36121 actttgctca ttccttggac ctttatcgtg gctatgcagc tattgtcgca ggagaggagt
    36181 tcccggcgtc agactttgaa actcagtatt gtttggctac ttctcgccgt gcaaatgctc
    36241 actatgttta ttcagaagag gatttgcttg ccaaatatag ccagcagttc aaggttaaaa
    36301 aagtcatgcc agctgccttc gcggaacttc aaggagatta cctgtatatg ctgaccactc
    36361 cgagtcgaca agaaatggag cagatgattg cagatttcgg acaacgtcaa gaataagaac
    36421 tatcggatta aggaaattaa ctcccttaat ccttttgttt tgtctgataa aaaataagag
    36481 catcccaaca aggtagctat cataaaactt gttcgataac tatttgaagc aggattaggt
    36541 ggtcagaaat taaattttaa tatttcaatt gagtcatagt attgtgtttg cgtatcctta
    36601 aatcagctaa aaggatccat gacgacacct atacgatata gttttcaaga taccaaacaa
    36661 gtctattaat attcaatgaa aatcaaagag caaactagga agctagccgc aggtttctca
    36721 aaacactgtt ttgaggttgt ggatagaact gacagagtca gtatcatata cctacggcaa
    36781 ggtgaagctg acgtggtttg aagagatttt cgaagagtat aaaatattca ggtgacgcat
    36841 agatatagtt aattgaagct ttgtttgaaa tctgataaaa taatgatatt actaagtttt
    36901 aaaaactaaa gaaaagggaa gatatgatta caggcgaatt aaaaaataaa atcgatcagc
    36961 tgtgggaaat tctttggaca gaaggaaacg caaatccttt aacaaatatt gaacagttga
    37021 cttatctctt atttatgaaa gatttggata gtgtcgagct tggacgtgaa agtgatgctg
    37081 aatttctagg gattccttat gagggagttt ttccaaaaga taaacctgaa taccgttggt
    37141 caacttttaa aaatatagga gatgctcagg aagtttatcg tttaatgact caggagattt
    37201 ttccgtttat taaaaatctc aagggggata cagatgatac agccttttca cgatatatgc
    37261 gagaagctat ttttcaaata aataaacctg ctacgcttca aaaggcaatt tctatcttag
    37321 atgtttttcc aactagggga ttagatgtag attttgataa tgacaaacaa agtattactg
    37381 atatcggaga tatctatgaa tatctgttat caaaattgtc gaccgcaggt aaaaatggac
    37441 agttccgtac acctcgtcac atcatcgata tgatggttga gttgatgcaa ccgactatca
    37501 aagatatcat ctcagatccc gctatgggtt ctgctggctt cttagtatct gctagccgtt
    37561 acttaaagcg taagaaagat gaatgggaaa ccaatacaga taatatcaat cattttcata
    37621 atcagatgtt tcatggaaat gatacggata cgactatgtt gagacttggg gcgatgaaca
    37681 tgatgctaca tggagtagaa aatccacaaa tcagttacct tgactcgctg tctcaagata
    37741 atgaagaagc cgataaatat actttggttt tagcaaatcc tccttttaag ggctcacttg
    37801 actacaattc aacctctaat gaccttcttg caaccgtaaa aaccaaaaaa acagaattac
    37861 tctttctttc tcttttcttg cgaactttaa aaccaggtgg acgagcagca gttatcgtac
    37921 ctgatggtgt cctttttggt tcgtctaaag ctcataaagg aattcgtcag gaaattgtag
    37981 agaatcataa gcttgatgct gtaatctcaa tgcctagtgg tgtgttcaag ccttatgctg
    38041 gagtttcaac tgccattctc atctttacaa aaactggtaa tggtggtact gacaaagtct
    38101 ggttttacga tatgaaagcg gatggtttaa gtttggatga taagcgacaa ccgattagcg
    38161 acaatgatat tccagatatt atcgaacgct ttcatcatct tgaaaaagaa gcagaacgtc
    38221 agagaacgga tcaatctttc tttgttccag ttgctgagat aaaggaaaat gattatgatt
    38281 tgtctatcaa taaatataaa gagattgagt atgaaaaagt tgagtatgaa ccaacagagg
    38341 tcatcttaaa gaaaatcaat gatttagaaa aagaaattca agctggcttg gctgaattag
    38401 aaaaattact caagtagaga ggtggctgta tgaaaaaagt gaagttgggg gaagtcttat
    38461 ctctaaaaaa aggcaagaaa gccactgtac ttgctgaaca aacaactcta agccaacgtt
    38521 atattcaaat agatgattta agaaataata ataatttaaa attcactgaa agtttaaata
    38581 tgactgaagc actcccagat gatattctga tagcatggga tggagctaat gcaggaacag
    38641 ttggttatgg attatcggga gctgttggta gtacaattac ggtcttaaaa aagaatgagc
    38701 gatacaaaga aaaaattata tcagattact tgggagtctt tttggaaagt aaatcgcagt
    38761 atttacgaga acattcaaca ggtgcaacaa ttcctcattt aaacaagaat atattacttg
    38821 atttacaatt agaattgcta ggtatcgaag aacaagagaa cattatctgt attcttaata
    38881 cgattaaaag gcttattact aaaagaaaat tgcagttaga tgaactaaac ttgctcgtca
    38941 aatcccgatt taacgagatg tttggggatg ttattctaaa tgaaaaagaa tggaaagtta
    39001 gcaaatggaa cgagattcta acaataagaa atggtaaaaa tcaaaaacag gttgaagatg
    39061 ctgatgggaa atttcctatt tatggaagtg ggggaattat gggatatgct aaagattgga
    39121 tagtgaagaa aaattcagtt attattggac gtaaaggaaa tataaataaa cctattttag
    39181 ttagagaaaa tttttggaat gtagatacag catttggatt agagcctgtt ttagaaaaaa
    39241 taaactcaga atatttattc tatttttgtc aattatacaa ttttgagaag ttaaataagg
    39301 ctgtaacaat acctagttta actaaatcag atttattaaa tatttccatc cccctccccc
    39361 cactagccct ccaaaatgag ttcgcagact ttgtagccct ggtcgacaaa tcacaatttg
    39421 cttgtgagat agctataaaa gtgtggagaa atagcttgaa atttagtata atatagctaa
    39481 actatttgtt taaagtgaga aaaaaatggg aaattttagc tttcttttaa aaaatgacga
    39541 atatgaatct ttttcaaaac cttgcattga agctgagaat atgattgcta catcaactgt
    39601 ggctactgcc tttatggcgc gtcgtgcttt agagcaggct gtccattgga tatatagtca
    39661 cgattcatat ttagaagctc cctatcgtgc tactctatct tctttagtat gggatgatga
    39721 ttttagggat atcgtagatt ctgaactcca caagcagata gttctgttga ttcggtgggg
    39781 aaaccatgct gctcatggtg gtgaaattaa ggaacgagaa gcgattttag ctttgcatca
    39841 tttgtatcag tttgttaatt ttatcgatta ttgttacagc aatgagtttg tggagcgtta
    39901 ttttgatgag aagtgcttac cactttcagc aaacatcaaa taccgagaaa ctccacaatc
    39961 tatgataaag ttacaagaca gtttaccaga actgcctgat tttcatgaac agatggctgc
    40021 tcagtccgta gaagttcaag agacttatac tgaaaaacgt gagactgcag cgcaacggca
    40081 agatgtgcct ttccatattg atcaattatc tgaggcagag acaagaaagc tctttattga
    40141 tatcgatctc cgtttagcag gatggatatt tgaagaaaac tgtcgtgttg agatagccgt
    40201 tgatggtctc aagcacggtt caggaattgg ttactgtgac tatgtacttt atggtaaaaa
    40261 tgggaaaatt ttagcgattg tggaggctaa aaaagcctct gtcaatccag aagtagggga
    40321 agtacaggtc aaagaatatg ctgaagcttt ggagaaacat atcggctatc agccaatttg
    40381 ctttattaca aatgggttga agcactatat acttgatggt ccgaaccgcc gccagattgc
    40441 aggcttttac tctcaagaag aattgcaatt agtgatggat agacgtcatc ttcaaaaacc
    40501 gcttgaggat atttctagta aaattaggga cgatatttcc gggcgtcact accaaaaaca
    40561 tgccattgca agcgtttgtg aagctttctc tgatcatcgt agacaggcac ttttggttat
    40621 ggcaactggg gcggggaaaa ctcgtacagc agtttctcta gttgatatct tatcacgtca
    40681 taactgggta aaaaacgttc tcttcttagc cgatagaact tccttggtta agcaagcata
    40741 tgattcgttt agaaaattac tcccagatct ttccgtttgt aacttcttag aagataaaga
    40801 aggagctcaa tcaagtcgaa tggtcttttc aacttatccg accatgattg gagcgattag
    40861 tggtcaagaa gaagtaaatc aacgcccttt tactgttggg cattttgacc ttatcataat
    40921 tgacgaatct caccgttcta tttatcagaa atacaagtcc atttttgatt attttgatgc
    40981 aaggattgta ggcttaacag ctactccgcg tcaagattta gataaaaaca cctatggatt
    41041 ctttaatttg gagaatgggg ttccaacata tgcatatgat ttggaagagg ctgttaaaga
    41101 cggatattta gtagcctatc attctatcga aaccaaactg aaactaccta cggatggtct
    41161 acattatgat gatttgtccg aagaagaaaa ggaacatttt gatagcaaat ttgaagacga
    41221 tagctgtgaa aaagatattg atgggagtgt gtttaattcc tttattttca ataaaagtac
    41281 agtagaaatt gttttaaatg aactcatgac aagaggaatt cagacagcct cgggtgatga
    41341 aattggtaaa actattattt ttgctaaaaa tcatgaccat gcggaatata tcagaggtat
    41401 ttttaacaac cgctatcctg aaaaagggag cgactatgct caggtgattg attatagtat
    41461 taagcattat cagaccttga ttgatgattt taaaattaag gagaagtatc ctcaaattgc
    41521 gatttctgtc gatatgttag atacaggtat tgatgtacca gaggttgtta atttagtctt
    41581 cttcaagaaa gtacgctcta aaactaagtt ttggcagatg attggtcgag gaacccgtct
    41641 atgtaaagat ttatttggac ctgagcagga taaggaaaac ttcttggtat ttgattatgg
    41701 ggacaatttt gattattttc gtgcagatcc aagagatgga gagggtcgtc acattgtttc
    41761 gctgactcag cgtttattta atatcaaagt ggacttgatt cgagaacttc agggactcca
    41821 ataccaagaa gatcagtttg cgagagcata ccgtcagcag cttgtctcgg aacttcaagg
    41881 tcgtatagag agcttaaatg agttggactt cagggttcgt atggttttag atacagttta
    41941 tagctatagg aaattggaaa gttggcagaa tctaactgct gttacaagtg aaaccattca
    42001 aaaaaatctc tctccgcttt tatttgatga agataaagaa gatgagatgg cgaggagatt
    42061 tgatttgtgg ttgcttcata ttcagttggg gcaactgaca gctaaatctt ccactgttca
    42121 tatttcccaa gtgatgaaga cggctagagc tctttctgct attggcaata tcccgcaggt
    42181 ttttgagcag gctgaaatta tggctctttg tcaactgtag tgggttgaaa aaaagctaag
    42241 cttgagaaag gacaaattt
//
LOCUS       DAVBDR010000011        40009 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.011, whole genome shotgun sequence.
ACCESSION   DAVBDR010000011 DAVBDR010000000
VERSION     DAVBDR010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 40009)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40009)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40009
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.011"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            650..2803
                     /locus_tag="VQ540_000622"
     CDS             650..2803
                     /locus_tag="VQ540_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000668284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
                     /protein_id="HET2544470.1"
                     /translation="MKFGKRHYRPQVDQMDCGVASLAMVFGYYGSYYFLAHLRELAKT
                     TMDGTTALGLVKVAEEIGFETRAIKADMTLFDLPDLTFPFVAHVLKEGKLLHYYVVTG
                     QDKDSIHIADPDPGVKLTKLPRERFEEEWTGVTLFMAPSPDYKPYKEQKNGLLSFIPI
                     LVKQRGLIANIVLATLLVTGINIVGSYYLQSIIDTYVPDQMRSTLGIISIGLVIVYIL
                     QQILSYAQEYLLLVLGQRLSIDVILSYIKHVFHLPMSFFATRRTGEIVSRFTDANSII
                     DALASTILSIFLDVSTVVIISLVLFSQNTNLFFMTLLALPIYTVIIFAFMKPFEKMNR
                     DTMEANAVLSSSIIEDINGIETIKSLTSESQRYQKIDKEFVDYLKKSFTYSRAESQQK
                     ALKKVAHLLLNVGILWMGAVLVMDGKMSLGQLITYNTLLVYFTNPLENIINLQTKLQT
                     AQVANNRLNEVYLVASEFEEKKTVEDLSLMKGDMTFKQVHYKYGYGRDVLSDINLTVP
                     QGSKVAFVGISGSGKTTLAKMMVNFYDPSQGEISLGGVNLNQIDKKALRQYINYLPQQ
                     PYVFNGTILENLLLGAKEGTTQEDILRAVELAEIREDIERMPLNYQTELTSDGAGISG
                     GQRQRIALARALLTDAPVLILDEATSSLDILTEKRIVDNLMALDKTLIFIAHRLTIAE
                     RTEKVVVLDQGKIVEEGKHADLLAQGGFYAHLVNS"
     gene            2816..4165
                     /locus_tag="VQ540_000623"
     CDS             2816..4165
                     /locus_tag="VQ540_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family secretion protein"
                     /protein_id="HET2544471.1"
                     /translation="MKPEFLESAEFYNRRYHNFSSSVIVPMALLLVFLLGFATVAEKE
                     MSLSTRATVEPSRILANIQSTSNNRILVNHLEENKLVKKGDLLVQYQEGAEGVQAESY
                     ASQLDMLKDQKKQLEYLQKSLQEGENHFPEEDKFGYQATFRDYISQAGSLRASTSQQN
                     ETIASQNAAASQTQAEIGNLISQTEAKIRDYQTAKSAMETGASLASQNLAYSLYQSYK
                     SQGEENPQTKVQAVAQVEAQISQLESSLATYRVQYAGSGTQQAYASGLSSQLESLKSQ
                     HLAKVGQELTLLAQKILEAESGKKVQGNLLDKGKITASEDGVLHLNPETSDSSMVAEG
                     ALLAQLYPSLEREGKAKLTAYLSSKDVARIKVGDSVRYTTTHDAGNQLFLDSTITSID
                     ATATKTEKGNFFKIEAETNLTSEQAEKLRYGVEGRLQMITGKKSYLRYYLDQFLNKE"
     gene            4336..5043
                     /locus_tag="VQ540_000624"
     CDS             4336..5043
                     /locus_tag="VQ540_000624"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HET2544472.1"
                     /translation="MSKQLIYSGKAKDIYTTEDENLIISTYKDQATAFNGVKKEQIAG
                     KGVLNNQISSFIFEKLNAAGVATHFVEKLSDTEQLNKKVKIIPLEVVLRNYTAGSFSK
                     RFGVDEGIALETPIVEFYYKNDDLDDPFINDEHVKFLQIAGDQQIAYLKEETRRINEL
                     LKVWFAEIGLKLIDFKLEFGFDKDGKIILADEFSPDNCRLWDADGNHMDKDVFRRGLG
                     ELTDVYEIVWEKLQELK"
     gene            5245..8970
                     /locus_tag="VQ540_000625"
     CDS             5245..8970
                     /locus_tag="VQ540_000625"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HET2544473.1"
                     /translation="MDKRIFVEKKADFQVKSESLVRELQHNLGLSSLKSIRIVQVYDV
                     FDLAEDLFAPAEKHIFSEQGTDHVLDEVSVQADLANYAFFAIESLPGQFDQRAASSQE
                     ALLLLGSSSDVTVNTAQLYLVNKDIDATELEAVKNYLLNPVDSRFKDITTGIAKQEFS
                     ESDKTIPKLTFFESYTAEDFARYKAEQGMAMEVDDLLFIQDYFKSIGRVPTETELKVL
                     DTYWSDHCRHTTFETELKHIDFSASKFQKQLQSTYDKYIAMREELGRSEKPQTLMDMA
                     TIFGRYERANGRLDDMEVSDEINACSVEIEVDVDGVKEPWLLMFKNETHNHPTEIEPF
                     GGAATCIGGAIRDPLSGRSYVYQAMRISGAGDITAPISETRAGKLPQQVISKTAAHGY
                     SSYGNQIGLATTYVREYFHPGFVAKRMELGAVVGAAPKGNVVREKPEAGDVIILLGGK
                     TGRDGVGGATGSSKVQTVESVETAGAEVQKGNAIEERKIQRLFRNGNVTRLIKKSNDF
                     GAGGVCVAIGELADGLEIDLNKVPLKYQGLNGTEIAISESQERMAVVVRPEDVDTFVA
                     ECNKENIDAVVVATVTEKPNLVMHWNGETIVDLERRFLDTNGVRVVVDAKVVDKDVKL
                     PEERQTSAETLESDTLTVLSDLNHASQKGLQTIFDCSVGRSTVNHPLGGRYQLTPTEA
                     SVQKLPVQHGVTHTASVIAQGFNPYVAEWSPYHGAAYAVIEATARLVAAGANWSKARF
                     SYQEYFERMDKQAERFGQPVAALLGSIEAQIQLGLPSIGGKDSMSGTFEELTVPPTLV
                     AFGVTTADSRKVLSPEFKAVGENIYYIPGQALSAEIDFDLIKKNFAQFEASQADHKVT
                     SASAVKYGGVVESLALATFGNYIGAEVTLPELKTALTAQLGGFVFTSPEEIAGVEKIG
                     QTKADFTLTVNGVKLDGHKLDSAFQGTLEEVYPTEFTQAKELEEVPAVASDVVIKAKE
                     KVEKPVVYIPVFPGTNSEYDSAKAFEKEGAEVNLVPFVTLNEEAIVKSVETMVDNIDK
                     TNILFFAGGFSAADEPDGSAKFIVNILLNEKVRVAIDSFIARGGLIIGICNGFQALVK
                     SGLLPYGNFEDANSTSPTLFYNDANQHVTKMVETRIANTNSPWLAGVQVGDIHAIPVS
                     HGEGKFVVTAEEFAELRDNGQIFSQYVDFNGKPSMDSKYNPNGSVHAIEGITSKNGQI
                     IGKMGHSERYEDGLFQNIPGNKDQHLFASAVKHFTGK"
     gene            9063..10505
                     /locus_tag="VQ540_000626"
     CDS             9063..10505
                     /locus_tag="VQ540_000626"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HET2544474.1"
                     /translation="MTYEVKSLNEECGVFGIWGHPDAAKLTYFGLHSLQHRGQEGAGI
                     LSNDQGQLKRHRDMGLLSEVFRNPANLDKLTGAGAIGHVRYATAGEASVDNIQPFLFR
                     FHDMQFGLAHNGNLTNAASLKKELEQRGAIFSATSDSEILAHLIRRSHNPSLMGKIKE
                     ALSLVKGGFAYILLFEDKLIAALDPNGFRPLSIGKMANGAVVVSSETCAFEVIGAEWI
                     RDLKPGEIVIIDDEGIQYDSYTDDTQLAICSMEYIYFARPDSNIHGVNVHTARKRMGA
                     QLAREFKHEADIVVGVPNSSLSAAMGFAEESGLPNEMGLIKNQYTQRTFIQPTQELRE
                     QGVRMKLSAVSGVVKGKRVVMVDDSIVRGTTSRRIVQLLKEAGATEVHVAIGSPALAY
                     PCFYGIDIQTRQELIAANHTVEETRQIIGADSLTYLSIDGLIESIGIETDAPNGGLCV
                     AYFDGDYPTPLYDYEEDYRRSLEEKTSFYK"
     gene            10542..11564
                     /locus_tag="VQ540_000627"
     CDS             10542..11564
                     /locus_tag="VQ540_000627"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HET2544475.1"
                     /translation="MTNKNAYAQSGVDVEAGYEVVERIKKHVARTERAGVMGALGGFG
                     GMFDLSKTGVKEPVLISGTDGVGTKLMLAIKYDKHDTIGQDCVAMCVNDIIAAGAEPL
                     YFLDYVATGKNEPAKLEQVVAGVAEGCVQAGAALIGGETAEMPGMYGEDDYDLAGFAV
                     GVAEKSQIIDGSKVVEGDVLLGLASSGIHSNGYSLVRRVFADYTGEEVLPELEGKKLK
                     EVLLEPTRIYVKAVLPLIKEELVNGIAHITGGGFIENVPRMFADDLAAEIDESKVPVL
                     PIFKALEKYGQIKHEEMFEIFNMGVGLMLAVSPENVERVKELLDEAVYEIGRIVKKEN
                     ESVIIK"
     gene            11561..12106
                     /gene="purN"
                     /locus_tag="VQ540_000628"
     CDS             11561..12106
                     /gene="purN"
                     /locus_tag="VQ540_000628"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HET2544476.1"
                     /translation="MKKIAVFASGNGSNFQVIAEEFPVEFVFSDHRDAYVLERAKQLG
                     VLSYAFELKEFESKADYEAALVELLEEHQIALVCLAGYMKIVGPTLLSAYEGRIVNIH
                     PAYLPEFPGAHGIEDAWNAGVGQSGVTIHWVDSGVDTGQVIKQVRVPRLADDTIDRFE
                     ARIHEAEYRLYPEVVKALFTD"
     gene            12190..12699
                     /locus_tag="VQ540_000629"
     CDS             12190..12699
                     /locus_tag="VQ540_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000894002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HET2544477.1"
                     /translation="MLESKKTTRYVFYVYLMLLTWGILFKFETNPEFIAFFLAPRYIN
                     WIPFSEPLIVDGKIVFAEMLFNLIFFIPLGVCFPLIKTNLSSLRIVGTGFLISLLFEC
                     LQYILAIGITDITDLTLNTLGVCVGLLIYQIFIRVFKSQTRKWINILGMLSLGFAYLV
                     LLLLHLIGV"
     gene            12724..14271
                     /gene="purH"
                     /locus_tag="VQ540_000630"
     CDS             12724..14271
                     /gene="purH"
                     /locus_tag="VQ540_000630"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006146083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HET2544478.1"
                     /translation="MTKRVLISVSDKADIVEFAQELKKLGWEIISTGGTKVALDNAGV
                     DTIAIDDVTGFPEMMDGRVKTLHPNIHGGLLARRDLDSHLEAAKDNKIELIDLVVVNL
                     YPFKETILKPDVTYDDAVENIDIGGPSMLRSAAKNHASVTVVVDPADYAVVLDELAAN
                     GETSYETRQRLAAKVFRHTAAYDALIAEYFTAQVGENKPEKLTLTYDLKQPMRYGENP
                     QQDADFYQKALPTDYSIASAKQLNGKELSFNNIRDADAAIRIIRDFKDSPTVVALKHM
                     NPCGIGQADDIETAWDYAYESDPVSIFGGIVVLNREVDAATAEKMHGVFLEIIIAPSY
                     TDEALAILINKKKNLRILALPFNAQEASEVEAEYTGVVGGLLVQNQDVVKESPADWQV
                     VTKRQPTETEATALEFAWKAIKYVKSNGIIVTNDHMTLGVGPGQTNRVASVRLAIDQA
                     KDRLDGAVLASDAFFPFADNVEEIAKAGIKAIIQPGGSVRDQESIEAADKYGLTMVFT
                     GVRHFRH"
     gene            14393..15655
                     /gene="purD"
                     /locus_tag="VQ540_000631"
     CDS             14393..15655
                     /gene="purD"
                     /locus_tag="VQ540_000631"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000772208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HET2544479.1"
                     /translation="MKLLVVGSGGREHAIAKKLLESKDVEKVFVAPGNDGMTLDGLEL
                     VNISISEHSKLIDFAKTNDVAWTFIGPDDALAAGIVDDFNQAGLKAFGPTRAAAELEW
                     SKDFAKEIMVKYGVSTAAYGTFSDFEEAKAYIEKHGAPIVVKADGLALGKGVVVSETV
                     EQAVEAAHEMLLDNKFGDSGARVVIEEFFEGEEFSLFAFVNGDKFYIMPTAQDHKRAY
                     DGDKGPNTGGMGAYAPVPHLPQSVVDTAVDTIVKPVLEGMIKEGRPYLGVLYAGLILT
                     ADGPKVIEFNARFGDPETQIILPRLTSDFAQNITDILDSKEPNITWTDKGVTLGVVVA
                     SKGYPLNYSKGVELPVKTDGDIITYYAGAKFAENSRALLSNGGRVYMLVTTADTVKEA
                     QASIYQELSQQKIEGLFYRTDIGSKAIK"
     gene            16058..16546
                     /gene="purE"
                     /locus_tag="VQ540_000632"
     CDS             16058..16546
                     /gene="purE"
                     /locus_tag="VQ540_000632"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000805607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HET2544480.1"
                     /translation="MKPVISIIMGSKSDWATMQKTAEVLDRFGVAYEKKVVSAHRTPD
                     LMFKHAEEARSRGIKIIIAGAGGAAHLPGMVAAKTTLPVIGVPVKSRALSGVDSLYSI
                     VQMPGGVPVATMAIGEAGATNAALFALRLLSVEDKSIADALANFAEEQGKIAEESSNE
                     LI"
     gene            16533..17624
                     /gene="purK"
                     /locus_tag="VQ540_000633"
     CDS             16533..17624
                     /gene="purK"
                     /locus_tag="VQ540_000633"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000099033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HET2544481.1"
                     /translation="MSSSKTIGIIGGGQLGQMMAISAIYMGHKVIALDPAADCPASRV
                     AEIIVAPYNDVDALRQLADRCDVLTYEFENVDADGLDAVIKDGQLPQGTDLLRISQNR
                     IFEKDFLSNKAQVTVAPYKVVTSSLDLADIDLSKNYVLKTATGGYDGHGQKVIRSEAD
                     LEAAYALADSADCVLEEFVNFDLEISVIVSGNGKEVTFFPVQENIHRNNILSKTIVPA
                     RISESLADKAKAMAVRIAEQLNLSGTLCVEMFATDDDVIVNEIAPRPHNSGHYSIEAC
                     DFSQFDTHILGVLGAPLPVIKLHAPAVMLNVLGQHVEAAEQYVTENSSAHLHMYGKIE
                     AKHNRKMGHVTLFSDVPDSVDELGEGIDF"
     gene            17634..17861
                     /locus_tag="VQ540_000634"
     CDS             17634..17861
                     /locus_tag="VQ540_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazole carboxylase"
                     /protein_id="HET2544482.1"
                     /translation="MIQIIVNTFIEKDKTGAVVEVLYASADQDKVQAKYEELAAQYPE
                     NYLAIYDVPLDTDLNTLDHYPSVFIEKEEFE"
     gene            17924..19222
                     /gene="purB"
                     /locus_tag="VQ540_000635"
     CDS             17924..19222
                     /gene="purB"
                     /locus_tag="VQ540_000635"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HET2544483.1"
                     /translation="MINRYSRPEMANIWSEENKYRAWLEVEILSDEAWAELGEIPKED
                     VALIRKKADFDIDRILEIEQETRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLYKQANDIIRRDLENFTNIIADKAKEHKFTIMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAAGVEAGKISGAVGNFANIPPFVEEYVCDKLGIRAQEISTQVLPRDL
                     HAEYFAVLASIATSIERMATEIRGLQKSEQREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MTGLARVIRGHMITAYENVALWHERDISHSSAERIITPDTTILIDYMLNRFGNIVKNL
                     TVFPENMIRNMNSTFGLIFSQRAMLTLIEKGMTREQAYDLVQPKTAYSWDNQVDFKPL
                     LEADSEVTSRLTQEEIDEIFNPVYYTKRVDDIFERLGLGD"
     gene            complement(19277..23215)
                     /gene="strH"
                     /locus_tag="VQ540_000636"
     CDS             complement(19277..23215)
                     /gene="strH"
                     /locus_tag="VQ540_000636"
                     /EC_number="3.2.1.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HET2544484.1"
                     /translation="MKHEKQQRFSIRKYAVGAASVLIGFAFQAQTVAADGVTPTTTEN
                     QPTIHTVSDSPQSSENRTEETPKAELQPEAPKTVETETPATDKVASLPKTEEKPQEEV
                     SSTPSDKAEVVTPTSAEKETANKKAEEASPKKEEAKEVDSKESNTDKTDKDKPAKKDE
                     AKAEDDKPETEAGKERAATVNEKLAKKKIVSIDAGRKYFSPEQLKEIIDKAKHYGYTD
                     LHLLVGNDGLRFMLDDMSITANGKTYASDDVKRAIEKGTNDYYNDPNGNHLTESQMTD
                     LINYAKDKGIGLIPTVNSPGHMDAILNAMKELGIQNPNFSYFGKESARTVNLDNEQAV
                     AFTKALIDKYAAYFAKKTEIFNIGLDEYANDATDAKGWSVLQADKYYPNEGYPVKGYE
                     KFIAYANDLARIVKSHGLKPMAFNDGIYYNSDTSFGSFDKDIIVSMWTGGWGGYDVAS
                     SKLLAEKGHQILNTNDAWYYVLGRNADGQGWYNLDQGLNGIKNTPITSVPKTEGADIP
                     IIGSMVAAWADTPSARYSPSRLFKLMRHFANANAEYFAADYESAEQTLNEVPKDLNRY
                     TAESVAAVKEAEKAIRSLDSNLSRAQQDTIDQAIAKLQETVNNLTLTPEAQKEEEAKR
                     EVEKLAKNKVISIDAGRKYFTLNQLKRIVDKASELGYSDVHLLLGNDGLRFLLDDMTI
                     TANGKTYASDDVKKAIIEGTKAYYDDPNGTALTQAEVTELIEYAKSKDIGLIPAINSP
                     GHMDAMLVAMEKLGIKNPQAHFDKVSKTTMDLKNEEAMNFVKALIGKYMDFFAGKTKI
                     FNFGTDEYANDATSAQGWYYLKWYQLYGKFAEYANTLAAMAKERGLQPMAFNDGFYYE
                     DKDDVQFDKDVLISYWSKGWWGYNLASPQYLASKGYKFLNTNGDWYYILGQKPEDGGG
                     FLKKAIENTGKTPFNQLASTKYPEVDLPTVGSMLSIWADRPSAEYKEEEIFELMTAFA
                     DHNKDYFRANYNALREELAKIPTNLEGYSKESLEALDAAKTALNYNLNRNKQAELDTL
                     VANLKAALQGLKPAATHSGSLDENEVAANVETRPELITRTEEIPFEVIKKENPNLPAG
                     QENIITAGVKGERTHYISVLTENGKTTETVLDSQVTKEVINQVVEVGAPVTHKGDESG
                     LAPTTEVKPRLDIQKEEIPFTTVTRENPLLLKGKTQVITKGVNGHRSNFYSVSTSADG
                     KEVKTLVNSVVAQEAVTQIVEVGTMVTHVGDENGQAAIAEEKPKLEIPSQPAPSTAPA
                     EESKALPQDPAPVVIEKKLPETGTHDSAGLVVAGLMATLAAYGLTKRKED"
     gene            complement(23530..24246)
                     /locus_tag="VQ540_000637"
     CDS             complement(23530..24246)
                     /locus_tag="VQ540_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001007200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HET2544485.1"
                     /translation="MAIPKYQYIKDELKNKIISGQFSSGDKFYTEAELISMYDVSSIT
                     VVRALNDLAKDGYIVRQQGKGTFVSRARKHKLVEFSDIELFNAKDDKVTVLSIERGNK
                     LVYLEKLGLRGDQFYYKIERIRESNGVVYIYHTSYIPEQYINANYPNLEYYSSIYNRF
                     KLDYHIHMNDEHFEEINEIVFPTPEHAASVLGVDEQFPTVLQTKITKLESTGQVLEYS
                     ETYKRSDYYKIKFISCDRDH"
     gene            24594..26381
                     /locus_tag="VQ540_000638"
     CDS             24594..26381
                     /locus_tag="VQ540_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase"
                     /protein_id="HET2544486.1"
                     /translation="MTRFEIRDDFYLDGKSFKILSGAIHYFRVPPEDWYHSLYNLKAL
                     GFNTVETYVAWNLHEPREGEFHFEGDLDLEKFLQIAQDLGLYAIVRPSPFICAEWEFG
                     GLPAWLLTKNMRIRSSDPVYIEAVGRYYDQLLPRLVPRLLDNGGNILMMQVENEYGSY
                     GEDKAYLRAIRQLMEECGVTCPLFTSDGPWRATLKAGTLIEEDLFVTGNFGSKAPYNF
                     SQMQEFFDEHGKKWPLMCMEFWDGWFNRWKEPIITRDPKELADAVREVLEQGSINLYM
                     FHGGTNFGFMNGCSARGTLDLPQVTSYDYDALLDEEGNPTAKYLAVKKMMATHFSEYP
                     QLEPLYKESMELDAIPLVEKVSLFETLDSLSSPVESLYPQKMEELGQSYGYLLYRTET
                     NWDAEEERLRIIDGRDRAQLYVDGQWVKTQYQTEIGEDIFYQGKKKGLSRLDILIENM
                     GRVNYGHKFLADTQRKGIRTGVCKDLHFLLNWKHYPLPLDNPEKIDFSKGWTQGQPAF
                     YAYDFTVEEPKDTYLDLSEFGKGVAFVNGQNLGRFWNVGPTLSLYIPHSYLKEGANRI
                     IIFETEGQYKEEIHLTRKPTLKHIKGENL"
     gene            26378..26854
                     /locus_tag="VQ540_000639"
     CDS             26378..26854
                     /locus_tag="VQ540_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HET2544487.1"
                     /translation="MTIVGCRIDGRLIHGQVANLWAGKLNVSRIMVVDDEVVNNDIEK
                     SGLKLATPPGVKLSILPVEKAAANILAGKYDSQRLFIVARKPDRFLGLVEAGVPLETL
                     NVGNMSQTPETRSITRSINVVDKDVEDFHKLAEKGVKLTAQMVPNDPISDFLSLLK"
     gene            26882..27787
                     /locus_tag="VQ540_000640"
     CDS             26882..27787
                     /locus_tag="VQ540_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HET2544488.1"
                     /translation="MIQWWQILLLTLYSAYQICDELTIVSSAGSPVFAGFITGLIMGD
                     VTTGLLIGGNLQLFVLGVGTFGGASRIDATSGAVLATAFSVSQGIDAPLAITTIAVPV
                     AALLTYFDVLGRMTTTFFAHRVDAAIERFDYKGIERNYLLGAIPWALSRALPVFFALA
                     FGGAFVQSVVDFVEAYKWVADGLTLAGRMLPGLGFAILLRYLPVKRNLHYLAMGFGLT
                     AMLTVLYSYVTGLGGAVAGIVGTLPAEVAEKIGFVNNFKGLSMIGISIVGIFLAVLHF
                     KNSQKVAVAAPSTPSESGEIEDDEF"
     gene            27774..28589
                     /locus_tag="VQ540_000641"
     CDS             27774..28589
                     /locus_tag="VQ540_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HET2544489.1"
                     /translation="MTNSNYKLTKEDFNQINKRSLFTFQLGWNYERMQASGYLYMILP
                     QLRKMYGDGTPELKEMMKVHTQFFNTSPFFHTIIAGFDLAMEEKDGVGSKDAVNGIKT
                     GLMGPFAPLGDTIFGSLVPAIMGSVAATMAIAGQPWGIFLWIAVAVAYDIFRWKQLEF
                     AYKEGVNLINNMQSTLTALIDAASVLGVFMMGALVATVINFEISYKLPIGEKMIDFQD
                     ILNQIFPRLLPAIFTAFIFWLLGKKGMNSTKAIGIIIVLALALSALGHFALGM"
     gene            28596..29000
                     /locus_tag="VQ540_000642"
     CDS             28596..29000
                     /locus_tag="VQ540_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007284837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET2544490.1"
                     /translation="MTKSLILVSHGRFCEELRGSTEMIMGPQDNIYTVALLPEDGPEE
                     FTAKFEAVIEGLDDFLVFADLLGGTPCNVVSRLIMEGRDIDLYAGMNLPMVIEFINAS
                     LTGADADYKSRAAESIVKVNDLLAGFDDDEDE"
     gene            29299..30465
                     /locus_tag="VQ540_000643"
     CDS             29299..30465
                     /locus_tag="VQ540_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HET2544491.1"
                     /translation="MLHYTKEDLLELGAEITTREIYQQPDVWREAFEFYQAKREEIAA
                     FLQEIADKHDYIKVILTGAGTSAYVGDTLLPYFKEVYDERKWNFNAIATTDIVAKPAT
                     YLKKDVATVLVSFARSGNSPESVATVDLAKSLVDELYQVTITCAADGKLALQAHGDDR
                     NLLLLQPAVSNDAGFAMTSSFTSMMLTTLLVFDPTEFAVKSERFEVVSSLARKVLDKA
                     EDVKELVDLDFNRVIYLGAGPFFGLAHEAQLKILELTAGQVATMYESPVGFRHGPKSL
                     INDNTVVLVFGTTTDYTRKYDLDLVREVAGDQIARRVVLLSDQAFGLENVKEVVLGCG
                     GVLNDIYRVFPYIVYAQLFALLTSLKVENKPDTPSPTGTVNRVVQGVIIHEYQK"
     gene            30581..31618
                     /locus_tag="VQ540_000644"
     CDS             30581..31618
                     /locus_tag="VQ540_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HET2544492.1"
                     /translation="MKAYTERVFGNVEGEDVLAYRFETDGGYQLEVMTYGATILRYVA
                     PDKAGNFANVILGFDDFDSYVGNSPKHGASVGPVAGRIAGATFELNGKTYDLEVNNAS
                     NCNHSGSTGWDSSLFEVEEVSDHGLTLYTERTDGTGGFPGNLKIWISYHLEETGAYEI
                     SYKVTTDQDTLVNPTNHSYFNLSGDFTQTIDRHVFQLNTEGIYSIAPDGVPAKTPEAN
                     RDVVKHIYNGALLKDIFAEEDEQIQLASGLDHPFALPAGHDNAGFLYDQNSGRFLLFK
                     TEAPCFVVYTANFVDESVIIGGQPMLQHNGIALEAQALPDAIHSDLKGQVILKAGQTF
                     TSKTRYELVVK"
     gene            31826..32680
                     /locus_tag="VQ540_000645"
     CDS             31826..32680
                     /locus_tag="VQ540_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HET2544493.1"
                     /translation="MTYEYKSHIYLAETALNVKDLASQTAFYQQVIGLEILSQTETES
                     ILGLGGKVLVQLIQAQESGEVREYYGLYHLAILLPTRKALADVLKHLTDLQIPLVGGA
                     DHGYSEAIYLEDLEGNGIELYRDKPVSTWDIREDGRIIGVTEALAAQDIYELGERVEP
                     FILAEGTRMGHIHLSVKDSRKSSQFYQKVLGLEDKFSVPSASWIAAGDYHHHLAVNEW
                     GGKGLASRKQGLPGLAYYVIEVAHKKELLTIAQRAQEVDAPIKWMTSSQLEITDSDGI
                     VTRIRLAR"
     gene            32830..33087
                     /locus_tag="VQ540_000646"
     CDS             32830..33087
                     /locus_tag="VQ540_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HET2544494.1"
                     /translation="MTNSKYITCLKRSEGQLCGIQKMIEGDRDCADIVTQLTAVRSSV
                     ERVIEMIITENLTECINQPLDDSEAQKERLEKAIRYLIKRK"
     gene            complement(33463..33555)
                     /locus_tag="VQ540_000647"
                     /pseudo
     CDS             complement(33463..33555)
                     /locus_tag="VQ540_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(33591..33887)
                     /locus_tag="VQ540_000648"
     CDS             complement(33591..33887)
                     /locus_tag="VQ540_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000450185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HET2544495.1"
                     /translation="METSISMADFYGKYQNENLELIDVREAHEFQAGHAPGAKNLPLS
                     TLEQGYKELKPDHEYYVICQGGVRSASTCQFLISQGLTVTNVEGGMNAWPGQVE"
     gene            complement(33877..34038)
                     /locus_tag="VQ540_000649"
     CDS             complement(33877..34038)
                     /locus_tag="VQ540_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014932007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(FAD)-dependent dehydrogenase"
                     /protein_id="HET2544496.1"
                     /translation="MDKKQAYIVSCHSGLRSYIAEPILKQAGFTAQNLDGAYSLYKMV
                     NPEGVEYGN"
     gene            34108..34872
                     /locus_tag="VQ540_000650"
     CDS             34108..34872
                     /locus_tag="VQ540_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside phosphorylase"
                     /protein_id="HET2544497.1"
                     /translation="MIQKHAIPILEFDDNPQAVIMPNHEGLDLQLPKKCVYAFLDEEI
                     DRYAREVGADCVGEFVSATKTYPVYVINYKGEEVCLAQAPVGSAPAAQFMDWLIGYGV
                     EQIISTGTCGVLADIEENAFLVPVRALRDEGASYHYVAPSRYMEMQPEAIAAIEEVLE
                     DRGIPYEEVMTWTTDGFYRETAEKVAYRKEEGCAVVEMECSALAAVAQLRGVLWGELL
                     FTADSLADLDQYDSRDWGSEAFNKALELSLASVHHL"
     gene            35485..36864
                     /locus_tag="VQ540_000651"
     CDS             35485..36864
                     /locus_tag="VQ540_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000897732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HET2544498.1"
                     /translation="MLFKLSKEKIELGLSRLSPARRIFLSFALVILLGSLLLSLPFVQ
                     VESSRATYFDHLFTAVSAVCVTGLSTLPVAHTYNIWGQIICLLLIQIGGLGLMTFIGV
                     FYIQSKQKLSLRSRATIQDSFSYGETRSLRKFVYSIFLTTFLVESLGAILLSFRLIPQ
                     LGWGRGLFSSIFLAISAFCNAGFDNLGSTSLFAFQTDLLVNLVIAGLIITGGLGFMVW
                     FDLAGHVGRKKKGRLHFHTKLVLLLTIGLLLFGTATTLFLEWNNAGTIGNLPVADKVL
                     VSFFQTVTMRTAGFSTIDYTQAHPVTLLIYILQMFLGGAPGGTAGGLKITTFFVLLVF
                     ARSELLGLPHANVARRTIAPRTVQKSFSVFIIFLMSFLIGLILLGITAKGNPPFIHLI
                     FETISALSTVGVTANLTPDLGKLALSVIMPLMFMGRIGPLTLFVSLADYHPEKKDMIH
                     YMKADISIG"
     gene            36878..37543
                     /locus_tag="VQ540_000652"
     CDS             36878..37543
                     /locus_tag="VQ540_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001283913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HET2544499.1"
                     /translation="MSDRTIGILGLGIFGSSVLAALAKQDMNIIAIDDHAERINQFEP
                     VLARGVIGDITDEELLRSAGIDTCDTVVVATGENLESSVLAVMHCKSLGVPTVIAKVK
                     SQTAKKVLEKIGADSVISPEYEMGQSLAQTILFHNSVDVFQLDKNVSIVEMKIPQSWA
                     GQSLSKLDLRGKYNLNILGFREQENSPLDVEFGPDDLLKADTYILAVINNQYLDTLVA
                     LNS"
     gene            37657..37752
                     /locus_tag="VQ540_000653"
                     /pseudo
     CDS             37657..37752
                     /locus_tag="VQ540_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            37898..38347
                     /locus_tag="VQ540_000654"
     CDS             37898..38347
                     /locus_tag="VQ540_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HET2544500.1"
                     /translation="MKLLSIAISSYNAAAYLHYCVESLVIGGEQVGILIINDGSQDQT
                     QEIAECLASKYPNIVRAIYQENKCHGGAVNRGLAEASGRYFKVVDSDDWVDPRAYLKI
                     LETLQELESKGQEVDAFVTNFVYEKEGQSRKKSMSYESVLPVRQIFD"
     gene            38504..38914
                     /locus_tag="VQ540_000655"
     CDS             38504..38914
                     /locus_tag="VQ540_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 2"
                     /protein_id="HET2544501.1"
                     /translation="MYYLPVDFYRYLIGREDQSVNEQVMIKRIDQQLKVNRLLVDQLD
                     LSQVSHPKMREYLLNHIEITTVISSTLLNRSETAEHLAKKRQLWTYIQQKNPEVFQAI
                     RKTMLSRLTKHSVLPDRKLSNVVYQITKSVYGFN"
     gene            39030..>40009
                     /gene="pavB"
                     /locus_tag="VQ540_000656"
     CDS             39030..>40009
                     /gene="pavB"
                     /locus_tag="VQ540_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding SSURE repeat adhesin PavB"
                     /protein_id="HET2544502.1"
                     /translation="MKFNPNQRYTRWSIRRLSVGVASVVVASGFFVLVGQPSSVRADV
                     VNPTPGQVLPEETSGTKEGDLSEKPGDTVLTQAKPEGVTGNTNSLPTPTERTEVSEET
                     NSSSLDTLFEKDEEAQKNPELTDVLKETVDTADVDGTQASPAETTPEQVKGGVKENTK
                     DSIDVPAAYLEKAEGKGPFTAGVNQVIPYELFAGDGMLTRLLLKASDNAPWSDNGTAK
                     NPALPPLEGLTKGKYFYEVDLNGNTVGKQGQALIDQLRANGTQTYKATVKVYGNKDGK
                     ADLTNLVATKNVDININGLVAKETVEKAVKDNVKDSIDVPAAYLEKAKGEG"
BASE COUNT        11042 a         7777 c         9355 g        11835 t
ORIGIN      
        1 ttaattagaa aaaaattttt aaagtcttcg gagaagaaaa cagaaaaatc tgttaaaaaa
       61 taatcaaaac tataaatgat gaatctgaat caaaattatt ttgcgcatgt aaagaggagt
      121 cttatagtaa cgagtcaaaa aaggagtaac tatgaatcgt aatttagaac ggtgttatct
      181 attctgacta ggaatagatc ataccagagg tagcttagaa atagcaggga cattagaaat
      241 tgaagtaata aataggatgt cgtaagtgtt actatcaatg atttatttgt ttcaagcttg
      301 cctagggtga cagtaaaaaa tcaatttcct ttcaatagca tatttttagt gggcaggact
      361 cttgttctgc ctattttttt atccaaaaag tgcagttggg agggagatag gctcatttgg
      421 gaaggaagtc cagtttttgt ttagtgattg gggtaagata gttgttatca gatgagttta
      481 tactcttcga aaatcaaatt caaaccacgt caacgtcgcc ttgccgtata tatgtgactg
      541 acttcgtcag tcctatctac aacctcaaaa cagtgttttg agcagcctgc ggctagtttc
      601 ctagtttgct ctttgatttt cattgagtat tagggaaaag gagatgaata tgaaatttgg
      661 gaaacgtcac tatcgtccgc aagtggatca gatggactgc ggtgtagctt cattagccat
      721 ggtttttggc tactatggta gttattattt tttggctcac ttgcgagaat tggctaagac
      781 gaccatggat gggacgacgg ctttgggctt ggtcaaggtg gcagaggaga ttggttttga
      841 gacgcgagcc attaaggcgg atatgacgct ttttgacttg ccggatttga cttttccttt
      901 tgttgcccat gtgcttaagg aagggaaatt gctccactac tatgtggtga ctgggcagga
      961 taaggatagc attcatattg ccgatccaga tcccggggtg aagttgacta aactgccacg
     1021 tgagcgtttt gaggaagaat ggacaggagt gactcttttt atggcaccta gtccagacta
     1081 taagccttat aaggaacaaa aaaatggtct gctctctttt atccctatat tagtgaagca
     1141 gcgtggcttg attgccaata tcgttttggc aacactcttg gtaaccggga ttaacattgt
     1201 gggttcttat tatctgcagt ctatcattga tacctatgtg ccagatcaga tgcgttcgac
     1261 actagggatt atttctattg ggctagtcat cgtctacatc ctccagcaaa tcttgtctta
     1321 cgctcaggag tatctcttgc ttgttttggg gcaacgcttg tcgattgacg tgattttgtc
     1381 ctatatcaag catgtttttc acctccctat gtccttcttt gcgacacgca ggacagggga
     1441 gatcgtgtct cgttttacag atgctaacag tatcatcgat gcgctggctt cgaccatcct
     1501 ttcgattttc ctagatgtgt caacggttgt cattatttcc cttgttctat tttcacaaaa
     1561 taccaatctc tttttcatga ctttattggc gcttcctatc tacacagtga ttatctttgc
     1621 ctttatgaag ccgtttgaaa agatgaatcg ggataccatg gaagccaatg cggttctgtc
     1681 ttcttctatc attgaggaca tcaacggtat tgagactatc aagtccttga ccagtgaaag
     1741 tcagcgttac caaaaaattg acaaggaatt tgtggattat ctgaagaaat cctttaccta
     1801 tagtcgagca gagagtcagc aaaaggctct gaaaaaggtt gcccatctct tgcttaatgt
     1861 cggcattctc tggatggggg ctgttctggt catggatggc aagatgagtt tggggcagtt
     1921 gattacctat aataccttgc tggtttactt taccaatcct ttggaaaata tcatcaatct
     1981 gcaaaccaag cttcagacag cgcaggttgc caataaccgt ctaaatgaag tgtatctagt
     2041 agcttctgag tttgaggaga agaaaacagt tgaggatttg agcttgatga agggagatat
     2101 gaccttcaag caggttcatt acaagtatgg ctatggtcga gacgtcttgt cggatatcaa
     2161 tttaaccgtt ccccaagggt ctaaggtggc ttttgtgggg atttcagggt caggtaagac
     2221 gactttggcc aagatgatgg ttaattttta cgacccaagt caaggggaga ttagtctggg
     2281 tggtgtcaat ctcaatcaga ttgataaaaa agccctgcgc cagtacatca actatctgcc
     2341 tcaacagccc tatgtcttta acggaacgat tttggagaat cttcttttgg gagccaagga
     2401 ggggacgaca caggaagata tcttacgggc ggtcgaattg gcagagattc gagaggatat
     2461 cgagcgcatg ccactgaatt atcagacaga attgacttcg gatggggcag ggatttcagg
     2521 tggtcaacgt cagagaatcg ctttggcgcg tgctctcttg acagatgcgc cggtcttgat
     2581 tttggatgag gcgactagca gtttggatat tttgacagag aagcggattg tcgataatct
     2641 catggctttg gacaagacct tgattttcat tgctcaccgc ttgactattg ctgagcggac
     2701 agagaaggtg gttgtcttgg atcagggcaa gattgtcgaa gaaggaaagc atgctgattt
     2761 gcttgcacag ggaggctttt acgcccattt ggtcaatagc tagaaagagg agaggatgaa
     2821 accagaattt ttagaaagtg cggagtttta taatcgtcgt taccataatt tttccagtag
     2881 tgtgattgta cccatggccc ttctgctcgt gtttttactt ggctttgcaa ctgttgcaga
     2941 gaaggagatg agtttgtcca ctagagctac tgtcgaaccc agtcgtatcc ttgcaaatat
     3001 ccagtcaact agcaacaatc gtattcttgt caatcatttg gaagaaaata agctggttaa
     3061 gaagggggat ctcttggttc aataccaaga aggggcagag ggtgtccaag cggagtccta
     3121 tgccagtcag ttggacatgc taaaggatca aaaaaagcaa ttggagtatc tgcaaaagag
     3181 cctgcaagaa ggggagaacc actttccaga ggaggataag tttggctacc aagccacctt
     3241 tcgcgactac atcagtcaag caggcagtct tagggctagt acatcgcaac aaaatgagac
     3301 catcgcgtcc cagaatgcag cagctagcca aacccaagcc gaaatcggca acctcatcag
     3361 tcaaacagag gctaaaattc gcgattacca gacagctaag tcagctatgg aaacaggtgc
     3421 ttccttggcc agtcagaatc tagcctactc tctttaccag tcctacaagt ctcagggcga
     3481 ggaaaatccc caaactaagg ttcaggcagt tgcacaggtt gaagcacaga tttctcagtt
     3541 agaatctagt cttgctactt accgtgtcca gtatgcaggt tcaggtaccc agcaagccta
     3601 tgcgtcaggg ttaagcagtc aattggaatc ccttaaatcc caacatttgg caaaggttgg
     3661 tcaggaattg acccttctag cccagaaaat cttggaggca gagtcaggta agaaggtaca
     3721 gggaaatctt ttagacaagg ggaaaattac ggcgagtgag gatggggtgc ttcatcttaa
     3781 tcctgagacc agtgattcta gcatggttgc agaaggtgcc ctactagccc aactttatcc
     3841 atctttggaa agagaaggga aagccaaact cacagcctat ctaagttcaa aagatgtagc
     3901 aagaatcaag gtcggtgatt ctgttcgcta tactacgact catgatgccg ggaatcaact
     3961 tttcctagat tctactatta caagtattga tgcgacagct actaagactg agaaagggaa
     4021 tttctttaaa atcgaggcgg agactaatct aacttcggag caggctgaaa aacttaggta
     4081 cggggtggaa ggccgcttgc agatgattac gggcaagaaa agttatctac gttattattt
     4141 ggatcaattt ttgaacaaag agtaatgttc gtgtttttag agttaaataa tttttaaact
     4201 gtgagaaaga ttcttcttgc agttttttct ttacaatttt taaaaaaaca tctgctattt
     4261 attcggttaa attcttgtgt tttttggttt tttgtggtaa aatgtgctca agtaatacga
     4321 aaggcgaact ttaaaatgtc aaaacaattg atctattcgg gaaaagctaa agatatctat
     4381 acaactgagg atgaaaatct tattatttca acttacaagg accaggcgac tgctttcaac
     4441 ggtgtcaaga aggagcagat tgcaggtaag ggagtcttga ataatcagat ctcatctttt
     4501 atttttgaga aattaaatgc ggctggtgtg gcgactcact ttgtggagaa actttcagac
     4561 acggaacaac tcaataaaaa ggttaagatt attcctttgg aagtcgtgct ccgcaactat
     4621 actgctggtt ccttttcaaa acgttttggt gtggatgagg gaatcgcctt ggagactccg
     4681 attgtcgaat tttactacaa aaatgatgat ttggatgatc catttatcaa tgatgagcat
     4741 gtgaaattcc tacagattgc gggtgaccag cagattgcct acttgaagga agaaacgcgt
     4801 cgtatcaatg aactattgaa agtctggttt gctgagattg ggcttaaatt gattgacttt
     4861 aagctagagt tcggttttga caaggatggc aagattatct tggcagacga attttcacca
     4921 gataactgcc gcttgtggga cgctgatggc aaccacatgg ataaggatgt tttccgtaga
     4981 ggattgggag aactaaccga cgtttatgag attgtttggg aaaagttgca ggaattgaaa
     5041 taatctgttt gcaacggaaa accttcgtct ctcaactaaa aggactcagg ctgaaaaggt
     5101 cccccagacc ttttcactct gtagagaact aggtgaacta acagatgttt acgaaattgt
     5161 ctgggaaaag ttgcagggtt taaaataaca acctcaaggc tgtttgggaa tattgcaaga
     5221 gctgaaataa aggaataaga attgatggat aaacgtattt ttgttgaaaa aaaggctgat
     5281 tttcaggtca agtcagagag tttggttaga gagctccagc acaacttggg actgtcaagc
     5341 ttgaaaagta ttcgtattgt gcaagtatat gatgtatttg acttggctga ggacttgttt
     5401 gcacctgcag agaagcacat tttctctgag cagggaaccg accatgtttt agatgaagta
     5461 tctgtgcagg cggatcttgc taactatgct ttctttgcca ttgaaagtct gccagggcag
     5521 tttgaccagc gtgcagcttc gtcacaggaa gccttgcttt tgttgggaag ttcgagtgac
     5581 gtgacagtca acacagccca actttacttg gtgaataaag atattgatgc gactgagttg
     5641 gaagctgtca aaaactacct gctcaatcca gttgattctc gtttcaagga tatcacgaca
     5701 gggattgcca agcaggagtt ttcagagtca gacaagacca ttccaaaatt gactttcttt
     5761 gaaagctata cagcagaaga ctttgctcgc tacaaggccg agcaagggat ggccatggaa
     5821 gtggatgatt tgctctttat ccaagactac tttaagtcaa tcgggcgcgt gccaactgag
     5881 actgaactca aggttttgga cacttactgg tctgaccact gccgtcatac gacttttgag
     5941 acagagttga aacacatcga cttttcagct tctaaatttc aaaagcaatt gcagtcaacc
     6001 tatgacaagt atattgccat gcgcgaggag ttaggtcggt ctgaaaaacc acaaaccttg
     6061 atggatatgg cgactatttt cggtcgttat gagcgtgcta acggacgatt ggatgatatg
     6121 gaagtctctg acgaaatcaa tgcctgctca gttgaaattg aagtggatgt tgatggtgtc
     6181 aaggaacctt ggctcctcat gtttaaaaat gaaacccaca accatccaac agaaattgag
     6241 ccatttggtg gagcggctac ctgtatcggt ggagctattc gtgatccgtt gtcaggccgt
     6301 tcctatgttt accaagccat gcgtatttca ggtgctggtg atattacagc accgatttcg
     6361 gaaactcgtg ctgggaaatt gccacaacaa gtcatttcta aaacagcagc tcatggttat
     6421 tcttcatatg gtaaccagat tgggcttgcc acaacctacg ttcgtgaata cttccaccca
     6481 ggctttgtag ctaaacgtat ggaacttggt gccgttgttg gtgcggctcc caagggcaat
     6541 gttgtccgtg aaaaacctga agcaggtgat gtgatcatcc ttctcggagg caaaacaggt
     6601 cgtgatggtg tcggtggtgc gacgggctct tctaaggttc aaacagttga gtctgtagag
     6661 actgctggtg ctgaggttca aaaaggaaat gccatcgaag aacgcaagat tcagcgcctc
     6721 ttccgtaatg gcaatgtcac tcgtctgatc aagaagtcca atgactttgg ggcaggcggc
     6781 gtctgtgtgg ctatcggtga attggcagac ggtcttgaaa tcgacctcaa caaggtgcct
     6841 cttaaatacc agggcttgaa tggtacagaa attgccatct ctgaatcaca agaacggatg
     6901 gcggtcgtgg ttcgtcctga agatgtggat accttcgttg ccgaatgtaa caaagaaaat
     6961 attgatgctg ttgtggtggc gacagtaact gaaaaaccaa atcttgtcat gcactggaat
     7021 ggtgagacaa tcgttgactt ggagcgtcgt ttccttgaca ccaatggtgt gcgcgtggtt
     7081 gtcgatgcca aagttgtgga caaggatgtc aaactcccag aagagcgtca aacatctgct
     7141 gaaacactgg aatcagatac ccttacggtt ctatctgacc tcaaccatgc aagtcaaaaa
     7201 ggattacaga ctatctttga ctgctctgtt ggacgctcaa cggttaatca cccacttggt
     7261 ggtcgttacc aactcacacc aactgaggca tctgtgcaga aattgccagt tcaacacggt
     7321 gtgactcata ctgcgtcggt cattgctcaa ggtttcaacc catatgtagc tgaatggtct
     7381 ccataccacg gtgctgctta tgcggttatc gaagcaactg ctcgtttggt ggctgctggt
     7441 gccaactggt ctaaggctcg tttctcttac caagaatatt tcgagcggat ggacaagcaa
     7501 gcagagcgtt tcggtcagcc agtagctgct cttctaggtt ctattgaagc acaaattcag
     7561 cttggcttgc catctatcgg tggtaaggac tccatgtctg gtacctttga agaattgacc
     7621 gttccgccaa ccttggttgc ctttggggtg acgacggcag atagccgtaa ggtgctctct
     7681 ccagaattta aagctgttgg ggaaaatatc tactacatcc caggtcaagc cctctctgca
     7741 gagattgatt ttgacttgat taagaaaaat tttgctcagt ttgaagcaag ccaagctgac
     7801 cataaagtga cgtctgcatc agctgtcaaa tacggtggtg tagttgaaag tttggctctt
     7861 gctacctttg gaaactatat tggtgcagag gtgaccttgc ctgaacttaa aacagctttg
     7921 acagctcaat taggcggctt tgtcttcaca tctcctgaag aaattgctgg agtagagaag
     7981 attggacaaa cgaaagcaga ctttacactg actgtcaacg gtgtgaagct agatggacac
     8041 aagcttgaca gtgcatttca agggacattg gaagaagttt acccaacaga atttacccaa
     8101 gcgaaagaac tagaagaagt accagctgtg gcatcagatg ttgtgattaa agccaaagaa
     8161 aaggttgaaa aacctgtggt ttacatccca gtctttccag gaaccaactc agaatatgat
     8221 tcagctaagg ccttcgaaaa agaaggtgca gaggtcaatt tggtgccatt cgtgaccttg
     8281 aatgaagaag ctattgtcaa gtcagttgaa actatggttg acaatatcga caagactaat
     8341 attctcttct ttgccggtgg attctcggct gcggatgaac cagatggttc agctaagttt
     8401 atcgtcaata tcctgcttaa tgaaaaagtg cgtgtggcta ttgatagctt tatcgcccgt
     8461 ggtggcttga ttatcggtat ttgtaatgga ttccaagcct tagtcaaatc gggtctccta
     8521 ccatacggaa actttgaaga tgctaacagt actagtccaa ccctcttcta caatgatgcc
     8581 aaccaacacg tgaccaagat ggtggaaact cgcattgcca ataccaactc accatggttg
     8641 gctggtgtgc aagtgggcga tatccacgct attcctgttt cgcacggtga agggaagttt
     8701 gtcgtgacgg ctgaggaatt tgcagagctc cgtgacaatg gacaaatttt cagccaatac
     8761 gttgacttta acggtaaacc aagtatggat tctaagtaca atccgaatgg ttctgtccat
     8821 gccatcgaag gaattaccag caagaatggt caaatcatcg gtaagatggg ccactcagaa
     8881 cgttatgagg atggtctttt ccaaaatatc ccaggcaata aagaccaaca cctgttcgca
     8941 tcagcggtta aacatttcac tggaaaataa gacttacaga ttttctaata gatagtatca
     9001 gtaatgtaaa agtcatgtaa atctagctct tgatgattac aaatgaaaat taggtataaa
     9061 aaatgacata cgaagtaaaa tctcttaatg aagaatgtgg tgttttcggt atttggggac
     9121 atccagatgc tgctaagttg acctattttg gactccacag tcttcaacac cgtggtcagg
     9181 agggggcagg aatcctctcc aatgatcaag gacaactgaa gcgccatcgt gacatggggc
     9241 ttttatcaga agttttcaga aatccagcca atttggataa attgacagga gctggtgcga
     9301 ttgggcatgt gcgttatgcg actgctggcg aagcttctgt tgataacatc cagcccttcc
     9361 tcttccgttt tcacgatatg cagtttggct tggctcataa tggaaatctg accaatgcag
     9421 cctctctcaa gaaagaactg gaacaaagag gagcaatttt cagcgcgact tcggactctg
     9481 aaatcttggc tcacctcatt cgtcgtagtc ataatcctag cctgatgggc aaaatcaagg
     9541 aagcgctcag ccttgtcaaa ggtggttttg cctatatctt gctgtttgag gacaagttga
     9601 ttgcggctct tgaccctaat ggctttcgtc cgctttctat cgggaaaatg gccaacggag
     9661 cggtggttgt ttcctctgaa acctgtgctt ttgaggtcat tggtgccgag tggattcgtg
     9721 atttgaagcc aggtgagatt gtgatcattg atgacgaggg cattcagtat gacagctata
     9781 cagatgatac tcagttggcg atttgttcta tggagtatat ctactttgct cgccctgatt
     9841 ctaatatcca cggtgtcaat gtccatacgg cacgtaagag aatgggagcg caattggcgc
     9901 gagaatttaa gcatgaggca gatattgtag ttggtgtgcc caattcttcc ctaagcgcgg
     9961 ctatgggatt tgcggaagaa tcaggcttac caaatgaaat gggtctgatc aaaaaccaat
    10021 acacccagcg aacttttatc caaccgactc aagaattgcg ggagcaagga gtgcggatga
    10081 aactgtctgc tgtttcgggt gttgtcaaag gcaaacgtgt ggtcatggtg gatgattcca
    10141 ttgtacgtgg aacaacctct cgtcgtatcg ttcagctctt gaaagaagcg ggtgcgactg
    10201 aggttcacgt tgccattgga agtcctgcac tagcgtatcc atgtttctac gggattgata
    10261 tccagacccg tcaggagctg attgcagcca atcatacggt cgaagaaact cgccaaatca
    10321 ttggtgcgga cagtctgact tatctttcaa ttgatggctt gattgagtcg attggtatcg
    10381 aaacagatgc gccgaacggt ggtctctgtg tcgcttactt tgacggtgac tacccaacgc
    10441 ctctctatga ctacgaagaa gactatcgta gaagtttgga agaaaagacc agtttttaca
    10501 agtaggcgac agattctcca ttaaagaaaa ggaaaaaaca aatgacaaat aaaaatgcat
    10561 atgcccagtc gggtgtggat gttgaagcgg gttatgaagt tgttgaacgg attaaaaagc
    10621 acgtggcccg tacggagcgt gcaggtgtca tgggagctct tggtggcttt ggtggtatgt
    10681 ttgacctttc caagactggg gttaaagaac ccgtcttgat ttcagggact gacggtgtcg
    10741 gaaccaagct catgttggct atcaagtacg acaagcacga taccatcggg caggactgtg
    10801 tggccatgtg tgtcaacgac atcattgctg caggtgcgga acccctctat tttctcgact
    10861 acgtagcgac agggaagaat gaaccagcta agctagaaca agtggttgct ggtgtggcag
    10921 aaggttgtgt gcaggctggt gctgccctca tcggtgggga aacggctgaa atgccgggca
    10981 tgtacggcga agacgactat gacttggctg gttttgcggt cggtgtggct gaaaaatctc
    11041 aaatcattga cggttcaaag gtggtagagg gagatgttct tctcggactt gcttcaagtg
    11101 ggattcactc aaatggttac tctttggttc gtcgtgtctt tgcggattac acaggtgagg
    11161 aagtcctacc agaattggaa ggcaagaaac ttaaggaagt tctacttgag ccgactcgta
    11221 tctatgtcaa ggctgtcttg ccgctcatca aagaagagtt ggtcaacggc attgcccaca
    11281 tcacaggtgg tggctttatc gaaaatgtcc ctcgtatgtt tgcagatgac ctagctgctg
    11341 aaattgatga aagcaaagtt ccagtgcttc caattttcaa agcccttgaa aaatatggtc
    11401 agattaaaca cgaagaaatg tttgaaatct tcaatatggg tgtgggactt atgttggcgg
    11461 tcagccctga aaatgtagag cgtgtaaaag aattgttgga tgaagcagtc tatgaaattg
    11521 gtcgcatcgt caagaaagaa aacgaaagtg tcattatcaa atgaaaaaaa tagcggtttt
    11581 tgcctctggt aatggctcaa attttcaggt gattgccgaa gaatttccag tggagtttgt
    11641 cttttcagac catcgtgatg cctatgtgct tgagcgtgca aagcagctcg gcgttctgtc
    11701 ctatgctttt gaactcaagg agtttgagag caaggcagac tacgaagcag cccttgtcga
    11761 actcttggaa gaacaccaga ttgccttggt ttgcctagca ggctacatga aaatcgttgg
    11821 accaacctta ttgtcggctt atgaaggtcg gattgtcaac attcatccag cctacttgcc
    11881 agaatttcca ggagctcatg ggattgagga tgcttggaat gctggcgtgg gtcagtctgg
    11941 tgtgaccatt cactgggtgg attcgggtgt ggatacaggc caggtcatca aacaggttcg
    12001 tgtgccacga ctagctgatg ataccattga cagatttgaa gctcgcatcc atgaagcaga
    12061 gtacaggttg tatccggaag tagtgaaggc tctatttaca gattgacttt ttgatgattc
    12121 atatgatatc tttgatttta aattggagtc agtgtttgtt gaagacggct tcaaacggag
    12181 gtatttgtaa tgttagaatc taaaaaaaca actcgatatg tattttatgt ctatctgatg
    12241 ttattaactt ggggaatctt atttaagttt gaaacaaatc ctgaatttat agcatttttc
    12301 ttagctccaa ggtatatcaa ttggattcca ttttcagaac cactaatagt cgatggaaaa
    12361 attgtttttg ctgaaatgtt atttaatctg attttcttta ttccattagg tgtttgtttc
    12421 cctttgataa aaactaattt atctagttta agaatagtcg ggacaggttt cttgattagt
    12481 ttattgtttg agtgcttaca gtatatttta gcaataggta taacagatat aacggatttg
    12541 actttaaata cgctaggtgt ctgtgtaggc ttactgattt atcaaatttt tataagagtg
    12601 ttcaaatcac agactagaaa atggatcaat atcttaggta tgcttagcct tggttttgct
    12661 tatcttgttt tactgttact gcatttaatt ggtgtttaac taatgattaa aaaggagaat
    12721 ataatgacta aacgcgtctt aatcagcgtc tcagacaaag cggacattgt tgaatttgcc
    12781 caagaactca aaaaacttgg ttgggagatt atctcgacag gtggaactaa ggttgccctt
    12841 gataatgctg gggtggatac cattgctatc gatgatgtga ctggtttccc agaaatgatg
    12901 gacggtcgtg tgaagaccct ccacccaaat atccacggag ggcttctcgc tcgtcgtgac
    12961 ttggatagcc acttggaagc ggctaaggac aacaagattg agctcattga ccttgtggtg
    13021 gtcaaccttt acccatttaa ggaaactatc cttaaaccag atgtgactta tgatgatgca
    13081 gttgaaaata tcgatattgg tgggccatct atgcttcgtt cagcagcgaa aaatcatgcc
    13141 agtgttacag ttgtggtaga tcctgctgac tacgctgtgg ttttggacga attggcagca
    13201 aacggcgaaa cctcttatga aactcgccaa cgtttagcag ccaaagtatt tcgtcacaca
    13261 gcggcttatg acgccttgat tgcagaatac ttcacagctc aagtgggtga aaacaagcct
    13321 gaaaaactca ctttgactta tgacctcaag caaccaatgc gttacggtga gaatcctcaa
    13381 caagacgcgg acttttacca gaaagctttg cctacagact actccattgc ttcagccaaa
    13441 cagctcaacg ggaaagaatt gtcatttaat aatatccgtg atgcagatgc tgctatccgt
    13501 atcatccgtg acttcaaaga tagtccaacc gttgtggctc tcaaacacat gaatccatgt
    13561 ggaattggtc aagctgatga catcgagact gcttgggact acgcttatga gtctgaccca
    13621 gtgtctatct ttggtgggat tgtcgtcctc aaccgtgagg tggatgctgc gacagctgag
    13681 aagatgcacg gcgttttcct cgaaatcatc attgcaccaa gctatacgga tgaagcgcta
    13741 gccattttga tcaataaaaa gaaaaacttg cgtatccttg ccttgccatt taatgctcaa
    13801 gaggctagcg aagtggaagc agaatacaca ggtgtagtcg gtggacttct cgtgcaaaat
    13861 caagacgtgg tcaaggaaag cccagctgac tggcaagtgg tgactaaacg tcagccaact
    13921 gagacagaag cgactgctct tgagttcgct tggaaggcta tcaagtacgt caaatcaaat
    13981 ggtattatcg tgaccaacga ccacatgaca cttggtgttg gtccaggtca aaccaaccgt
    14041 gtggcttctg ttcgccttgc cattgaccaa gccaaagatc gtctggacgg ggcggtcctt
    14101 gcttcagatg ccttcttccc atttgcggat aacgtggaag aaatcgccaa agcaggaatt
    14161 aaggccatca tccagcctgg tggctctgtc cgtgaccaag aatccatcga agcagcggat
    14221 aaatacggct tgactatggt ctttacaggt gtgagacatt ttagacatta agaagataaa
    14281 agggaagaaa acagtttctt tccttttttg gcttaaaatg ctaactgaaa caagattaaa
    14341 acgaactttt ttgatataat gttggtaaat aattcgcaaa agaggttgag gaatgaaact
    14401 gcttgttgtc ggttctggtg gtcgtgagca tgcgattgct aaaaagttac ttgaatcaaa
    14461 agacgtggaa aaagtctttg tagctcctgg gaatgatggg atgactctgg atggtttgga
    14521 attggtaaat atctctattt ccgaacattc taaattgatt gacttcgcaa agaccaatga
    14581 tgttgcttgg acctttatcg gtccagatga tgcccttgct gctggtatcg tggatgattt
    14641 taaccaagct gggcttaagg cctttggtcc gactagggct gcagcggagc tggagtggtc
    14701 caaggatttt gccaaggaaa tcatggtcaa atatggtgtt tcgacagcag cctatggcac
    14761 attttcagat ttcgaggaag caaaggccta tatcgaaaag catggtgcgc ctatcgtagt
    14821 caaggcggat ggcttggcgc ttgggaaggg tgtcgtcgtt tctgagacgg ttgagcaagc
    14881 ggtcgaagcc gctcatgaga tgcttttgga caataaattt ggtgactcag gtgcgcgcgt
    14941 ggttattgag gaattctttg aaggagagga attttcactc tttgcctttg tcaatggtga
    15001 taagttctac atcatgccaa cggctcagga ccacaaacgt gcctatgatg gcgacaaagg
    15061 gcctaacacg ggtggtatgg gtgcctatgc gccagttcca cacttaccac agagtgtagt
    15121 tgatacagcg gttgacacca ttgtcaagcc agttctagaa gggatgatta aagaaggtcg
    15181 cccttatctg ggagttcttt acgcagggct tatcctgaca gctgatggac cgaaagtcat
    15241 tgagttcaac gctcggttcg gagatccaga aactcagatt atcttgcctc gcttaacctc
    15301 tgactttgct caaaatatca cagatatcct ggatagcaag gagccaaata tcacgtggac
    15361 ggacaagggt gtgactctgg gtgtggttgt cgcatccaag ggctacccgc taaattattc
    15421 aaagggtgtt gagttgccag tcaaaaccga tggcgacatc attacctact atgcaggggc
    15481 taagtttgcg gaaaatagca gagcactgct ctcaaacggc ggacgagttt atatgctcgt
    15541 taccacagca gataccgtca aagaagccca agccagcatc taccaagaac tatcccaaca
    15601 aaaaatagaa ggactcttct accgaacaga tatcggaagc aaggcaatta agtaaagata
    15661 taagaataac gcgccgtagt cgccaaacac gataatggtc gtcgtggtga aaagaccaga
    15721 acagtgaatg ttctggtcag ggggaaactt ggagaccgta ggctcaaagt ttaggaatga
    15781 aaccgaaggt ttgcttccgc ctccatcacc taagaccatt atcaaaaaga aaaataaaaa
    15841 ttcacaaaat acgttaatga tcgtatggtt tgcgagcgtt agcgagctaa tatagaacaa
    15901 tcaccgccgt tgtgaaagaa cgattggatg ataatccaat cgttcaggga aattggaaga
    15961 ccttgggttt ccaatttagg catgagacac ctttggtggc tgctgccgtc cctcacaagc
    16021 taaggtgatt gttgaaaaag aggaaaaagg agaagaaatg aaaccagtaa tttccatcat
    16081 catgggctca aaatccgact gggcaaccat gcaaaaaaca gcagaagtcc tagaccgctt
    16141 cggtgtagcc tacgaaaaga aagttgtttc cgcacaccgc acaccagacc tcatgttcaa
    16201 acatgcagaa gaagcccgta gtcgtggcat caagatcatc atcgcaggtg ctggtggcgc
    16261 agcgcatttg ccaggcatgg tagctgccaa aacaaccctt ccagtcattg gtgtgccagt
    16321 caagtctcgt gctcttagtg gagtggattc actctattct atcgttcaga tgccgggtgg
    16381 ggtgcctgtt gcgaccatgg ctatcggtga agctggagcg actaacgcag ctctctttgc
    16441 cctccgtctc ctctctgtag aagataagtc cattgcggat gcacttgcca actttgctga
    16501 agaacaagga aaaatcgcag aggagtcgtc aaatgagctc atctaaaaca atcggaatta
    16561 tcggtggcgg tcaactgggt cagatgatgg ccatttctgc tatctacatg ggccacaagg
    16621 ttatcgcgct ggatcctgcg gcggattgcc cggcctctcg cgtggcggaa atcattgtgg
    16681 caccttataa cgatgtggac gccctccgtc agttggcaga ccgttgcgat gtcctcactt
    16741 atgagtttga aaatgtcgac gctgacggtt tggatgccgt tatcaaggat ggacaactcc
    16801 ctcaaggaac agatctgctc cgcatttcgc aaaatcgtat ttttgaaaag gactttttgt
    16861 caaacaaggc tcaagtcact gtggcaccct acaaggtcgt gacttctagc ctagacttgg
    16921 cagatatcga cttgtcgaaa aactatgtcc tcaagactgc gactggtggc tacgatggtc
    16981 atggacaaaa ggttattcgt tcagaagcag acttggaagc agcctatgcg ctagcagact
    17041 cagcagactg cgtcttggaa gaatttgtca actttgacct tgagatttct gtcatcgtgt
    17101 caggaaatgg caaggaggtg acgtttttcc cagttcagga aaatatccac cgcaacaata
    17161 tcctgtctaa gaccatcgta ccagcccgca tttctgaaag tctagcagac aaggctaaag
    17221 ctatggcagt gcgaatcgca gaacaactca acttgtctgg aactctctgt gtggaaatgt
    17281 ttgcgactga tgatgacgtt attgtcaatg aaatcgcccc acgaccacat aactctgggc
    17341 actattctat tgaagcctgt gatttctctc agtttgacac ccatattctg ggtgttctcg
    17401 gagcaccatt accagtcatc aaactccatg cgccagccgt tatgcttaat gtcctcggtc
    17461 agcatgtcga ggctgctgag caatatgtga cagaaaattc aagcgcccac ctccacatgt
    17521 atggtaaaat agaagcgaag cacaaccgca agatgggaca tgtgaccttg tttagtgatg
    17581 taccggatag tgtggatgag cttggggaag ggattgattt ttaggacaag tctatgatac
    17641 aaattatcgt taatacattt attgaaaagg ataagactgg agcagttgtt gaagtgttgt
    17701 atgccagtgc tgaccaagat aaggtacaag ctaaatatga agaactagct gcacaatacc
    17761 ccgaaaatta tttagctatc tatgatgtac cgctggatac ggatttgaat acactagatc
    17821 attacccgtc tgtgtttatt gaaaaagagg agtttgagta gaaatcttgg tttacctaga
    17881 tagcttattc ccaacagctt aagaagaaag gaaaaattaa cacatgatca accgttactc
    17941 tcgccctgag atggcgaata tttggagtga agaaaataaa taccgtgctt ggcttgaggt
    18001 ggaaatcctc tctgacgagg catgggctga gttgggggaa atccctaagg aagatgtggc
    18061 tttgattcgc aagaaggcgg actttgacat cgaccgtatt ttggaaattg agcaggagac
    18121 gcgccacgat gtggtggctt tcacgcgtgc ggtttctgag actcttggtg aagagcgcaa
    18181 gtgggttcac tatgggttaa cttctaccga cgtggtggat actgcttatg gttacctcta
    18241 caagcaggcc aacgacatca tccgtcgtga ccttgaaaac ttcactaata tcatcgctga
    18301 caaggccaag gagcacaagt tcaccatcat gatggggcgt actcatggtg tgcacgctga
    18361 gccgacaacc tttggtctta aattggcaac ttggtacagc gaaatgaaac gcaatatcga
    18421 gcgtttcgag catgcagctg ctggtgtaga agctggtaag atttctggtg cggttgggaa
    18481 ctttgccaat atcccaccat ttgtagagga gtatgtctgc gataaacttg gcatccgtgc
    18541 ccaagaaatc tctacacaag tccttcctcg tgaccttcac gctgagtact ttgcggttct
    18601 tgccagcatt gcgacttcaa tcgaacgtat ggcgactgag attcgtggtc tacaaaaatc
    18661 tgagcaacgc gaagtagaag agttctttgc taaagggcaa aaagggtctt cagcaatgcc
    18721 tcacaaacgc aacccaatcg gttctgaaaa tatgactggt ctggcgcgtg tcattcgtgg
    18781 tcacatgatt acggcttatg aaaacgtcgc tctctggcac gaacgcgata tttctcactc
    18841 atcagctgag cgtatcatca caccagatac gaccattttg attgactaca tgctcaaccg
    18901 ttttggaaat atcgtcaaga acttgacagt cttcccagaa aatatgatcc gaaacatgaa
    18961 ctcgactttt ggtcttatct ttagccaacg ggctatgttg acattgattg aaaaaggcat
    19021 gacccgtgag caagcctatg acttggtgca accaaaaaca gcctactctt gggacaacca
    19081 agtagacttt aaaccacttc ttgaggcaga ttcagaagta acatcacgtc tcactcaaga
    19141 agaaatcgat gaaatcttca acccagttta ttacaccaaa cgagtggatg atatctttga
    19201 acgtcttgga ctaggtgatt aattaaaaaa taaacagcga gcttcaatct cgctgtttat
    19261 tttttatcga aaagacttag tcttcttttc ttttagtgag tccataggct gctagtgtgg
    19321 ccatgagtcc tgcgactact agtcctgcag aatcgtgagt tcctgtttca ggaagttttt
    19381 tctctattac cacaggagct ggatcttgag gaagagcttt gctttcctca gcaggagcag
    19441 ttgatggagc tggttggctt gggatttcta gttttggttt ttcttcagca atagcggctt
    19501 gtccgttttc atcgcctaca tgtgttacca tagttccgac ttcgactatt tgagtaacgg
    19561 cttcctgtgc tacgacacta tttacaagtg ttttcacttc cttaccatcg gcagaagtgc
    19621 tcacagagta gaagttgcta cgatgtccat tgacgccctt agtaatgact tgtgtttttc
    19681 ctttgagtaa gagtggattt tcacgagtca ctgtggtaaa tggaatttct tctttttgga
    19741 tatccagtct aggttttacc tcagtagttg gtgcaagacc actttcatca cccttgtgag
    19801 ttacaggagc gccaacttca accacttggt ttataacttc tttggttacc tggctatcaa
    19861 ggactgtttc tgttgttttt ccattttcag tgagtacaga gatgtaatga gttcgctcac
    19921 ctttgactcc tgctgtgata atattttcct gaccagctgg gaggttagga ttttctttct
    19981 tgataacttc aaatggaatt tcttcagttc ttgtgatgag ttctggtctg gtttcaacat
    20041 tggcagccac ttcattttca tccaggcttc ctgaatgagt tgcagctggt ttgaggcctt
    20101 gaagagcggc ttttaggttg gctacaagtg tgtcaagctc agcttgttta ttacggttga
    20161 ggttgtaatt tagagctgtt ttagctgcgt caagggcctc aagactttct ttactatatc
    20221 cttctaagtt tgtaggaatt ttagctaatt cttcgcggag agcattataa ttagcacgga
    20281 agtagtcttt gttgtggtct gcaaaggcag tcatgagttc aaagatttcc tcttccttgt
    20341 attcagcgct tggtctatct gcccagattg aaagcatact tccgactgtt ggaagatcta
    20401 cttcaggata tttggtagaa gctagttgat tgaatggtgt ttttccagta ttctcaatag
    20461 ctttcttgag gaaaccacca ccatcttctg gtttttgacc aagaatgtag taccagtcac
    20521 cgttggtatt caagaattta tagcctttgc ttgctaggta ttgaggtgat gcgaggttat
    20581 atccccacca gcctttagac cagtaagaaa tcaagacatc tttgtcaaac tgaacatcgt
    20641 ccttgtcttc atagtagaag ccatcgttga aggccattgg ttgaagccct ctttctttgg
    20701 ccatagctgc gagggtgttg gcatattcgg caaatttgcc atagagttga taccacttga
    20761 ggtagtacca gccttgggca ctagtcgcat cgttggcgta ttcgtcagta ccaaagttga
    20821 aaatctttgt tttacctgca aagaagtcca tgtatttacc gatgagggct tttacaaagt
    20881 tcatcgcttc ttcgtttttc aagtccatag ttgtttttga aactttatca aagtgggctt
    20941 gaggattttt aatacctaat ttttccatgg caaccagcat agcatccatg tgacctggac
    21001 tgttaatagc tgggatgaga ccgatgtcct tagatttagc gtattcaatt agctctgtta
    21061 cttctgcctg tgttagtgca gtaccgtttg gatcgtcgta gtaagcttta gttccttcga
    21121 taatagcttt tttaacgtca tcactagcat aggtttttcc gttggcagta atggtcatat
    21181 catcgagtag aaagcgaagt ccgtcatttc ctagaaggag atggacatca gaatatccga
    21241 gctcactggc cttgtctacg atgcgtttga gctggttcag agtaaagtat ttgcgtccag
    21301 catcgattga gattaccttg tttttggcaa gtttttcaac ctcacgttta gcttcttctt
    21361 ctttttgagc ttcaggcgtg agggtcaagt tgttgacagt ttcttgaagt ttagcaatgg
    21421 cttgatcaat cgtatcttgt tgggcacggc taaggttgct atcgagagag cgaatagctt
    21481 tttcagcttc ttttacggcc gcgacgcttt ctgcagtata acggttcagg tcttttggta
    21541 cctcgttaag tgtttgctct gcagattcat aatcagctgc gaagtattca gcgttggcat
    21601 ttgcaaaatg acgcatgagt ttgaagaggc gtgatggtga ataacgtgca gatggagtgt
    21661 cagcccaagc agctaccata ctaccgatga ttgggatatc agctccttct gtttttggta
    21721 cagaagtgat tggtgtgttt ttaataccat tgagcccctg atcgagattg taccagcctt
    21781 ggccatcagc gtttcgtcca agaacgtagt accaagcatc attggtatta aggatttggt
    21841 gacctttttc agctagtagt ttagaagaag cgacatcgta gcctccccaa ccaccagtcc
    21901 acatagaaac gatgatgtct ttgtcaaaac taccaaagct tgtgtcgcta ttgtagtaga
    21961 taccgtcgtt aaaggccatt ggtttgagac cgtgcgattt tacaatacga gcgaggtcat
    22021 tggcgtaggc aataaatttt tcatagcctt ttacagggta gccttcgttt ggatagtatt
    22081 tatcagcttg aagcacactc caacctttag catctgtcgc atcattggca tattcatcaa
    22141 gtccgatgtt gaagatttca gtctttttcg cgaaataagc agcatacttg tcgataaggg
    22201 cttttgtaaa agcgacagct tgttcgttgt caagattgac agtacgggct gattccttcc
    22261 caaaatagct aaagttaggg ttttggattc ccaattcttt catggcattg agaatcgcat
    22321 ccatgtgacc aggactattt actgtcggaa tgagaccgat acctttatct ttggcatagt
    22381 taatcagatc tgtcatttga ctttctgtta agtgattgcc gtttggatcg ttgtaataat
    22441 catttgtacc tttttcaatg gcgcgtttga catcgtcact ggcataggtc ttgccgttag
    22501 ctgtgatgct catatcgtcc aacatgaaac ggagtccatc atttccgact aataggtgta
    22561 aatcagtgta gccataatgt ttcgctttat cgatgatttc cttgagctgt tctggtgaga
    22621 aatatttacg tccagcatca atagaaacaa ttttcttttt cgctagtttt tcatttacag
    22681 ttgcagcacg ttcctttcct gcctctgttt ccggtttgtc atcctctgct ttcgcttcat
    22741 cttttttagc tggtttatcc ttgtcagtct tgtctgtatt tgactcttta gaatcaacct
    22801 ctttcgcttc ttccttttta gggctagctt cttctgcctt tttattagca gtttcttttt
    22861 cagcagaagt tggagttacc acttctgctt tatcactagg agttgaacta acttcctctt
    22921 gtggtttttc ttctgttttt ggaagactag ctaccttatc agtagctgga gtttctgttt
    22981 ctacagtttt tggagcttct ggttgaagct ctgctttagg tgtttcctca gtccgatttt
    23041 cggatgattg aggggaatca gaaaccgtat ggatggtcgg ttggttttct gtagtagtag
    23101 gagtaactcc atcggctgca acagtctgtg cttggaaggc aaatccaatt agaacagaag
    23161 ctgctcctac agcgtattta cgaatagaaa aacgctgttg tttttcatgt ttcattgcaa
    23221 aacctcctga ttgcattgtt atattgatag cgattatata aatcaacgcc tttattttat
    23281 ttcttatatt aacgagagtc aagaggagat gacaaaaaac tataataagt ataaaaaaat
    23341 ataaaattta aacttaagat ttcagattgg tcggaaaaaa tacgtatata tatctagtat
    23401 aatttttggt tctatttcta taaaatattc cacaaattat agaattttcc aaaaataggt
    23461 aagcgctacc tttttggtgt ggtataataa gcatagaaaa agcccaagcg attagctcag
    23521 gctttcttct tagtgatcac ggtcacatga gataaattta atcttgtagt aatcagatcg
    23581 tttgtaagtt tcactgtatt ctaaaacttg gccagttgat tcgagtttgg tgattttagt
    23641 ttgtaggaca gtagggaatt gttcatcgac tccgaggact gaagccgcat gttctggagt
    23701 tggaaagact atttcgttga tttcttcaaa gtgttcatca ttcatgtgaa tgtggtagtc
    23761 taacttgaaa cgattataga tagaactata gtattcaagg tttggataat ttgcgttgat
    23821 atattgttct gggatgtagg atgtatggta gatataaacg acaccgtttg attcgcggat
    23881 acgttcaatc ttgtagtaga attgatcgcc gcgtagaccc aatttttcca agtaaacaag
    23941 cttgtttccg cgttcaattg aaagaacagt taccttatca tctttagcat tgaagagttc
    24001 aatatctgaa aactctacaa gcttgtgttt gcgtgcacgt gaaacgaagg ttccttttcc
    24061 ttgttggcgg acaatatagc catctttggc aaggtcgttt aaggcgcgaa caactgtgat
    24121 agagctgaca tcgtacattg aaatgagttc tgcttcagtg taaaatttat ctccactgct
    24181 aaactgccca gagatgattt tattttttaa ttcgtctttt atgtattgat atttgggaat
    24241 tgccatattt ttacctctat tttccttctc cataggaaat tttaccataa aagcgaaaaa
    24301 aatagtagtc ttttgaataa aaaattagaa taatagtttg aaaaattaag cgatataggg
    24361 attgctcata ttttatcaat gtattctata caaaattatt ttaggtccca tattccgaat
    24421 ttaaagagcg tttgaaatgg gtctaaaaat gtttgaaact aattgaatgt gtgtataata
    24481 gtaaaaatgc agtaaatatc ccgacaattt ctattgacaa ttcaaacaga ttggtttata
    24541 attaatataa caacaaatga aagcgcaaac tttcgcggtc ggaaggtagt tttatgacac
    24601 gatttgagat acgagatgat ttctatctcg atggaaaatc atttaagatt ttatctggtg
    24661 ccattcatta ttttagggtt cctccagagg attggtatca ttcgctctat aacttgaagg
    24721 ctcttggttt taatacggta gagacttatg ttgcttggaa tttacacgag cctcgtgaag
    24781 gtgagtttca ttttgaaggt gatctggatt tagagaaatt tctccaaata gcgcaggatt
    24841 tgggtctcta cgcaattgtg cgtccgtctc catttatctg tgcggaatgg gaattcggtg
    24901 gcttaccagc ttggctcttg accaagaaca tgcgaattcg ctcatccgac ccagtatata
    24961 tcgaggcagt tggtcgctac tatgatcagt tattgccaag actggtgcct cgtttgttgg
    25021 acaatggtgg caatattctc atgatgcagg ttgaaaatga gtatggttct tacggagaag
    25081 ataaggctta cctgagagcg attcgacagc taatggaaga gtgtggcgta acctgtcccc
    25141 tctttacatc agatggtcca tggcgagcta ctctgaaagc tggaacctta attgaagagg
    25201 acctctttgt aacaggaaac tttggttcta aggcacctta caacttttcg cagatgcagg
    25261 aattctttga tgaacatggt aagaaatggc cactcatgtg tatggagttc tgggatggtt
    25321 ggttcaatcg ctggaaagaa ccgattatca cacgggatcc taaggaattg gcagatgcag
    25381 ttcgagaggt tttggaacaa ggctctatca atctttacat gttccacggt ggtacaaact
    25441 ttggtttcat gaatggttgc tcagctcgag gaactttgga cctgccacaa gttacgtctt
    25501 atgattacga tgcccttctg gatgaagaag gaaatccaac tgctaaatat cttgcagtca
    25561 agaagatgat ggcaacacat ttttcagagt atccgcagtt ggaaccactc tacaaagaga
    25621 gtatggagtt ggatgctatt ccactagttg aaaaagtttc tttgtttgaa accttagata
    25681 gcttgtcaag tcctgtagaa agtctctatc ctcaaaagat ggaggagctg ggacaaagtt
    25741 atggctacct actttatcga acagaaacaa actgggatgc agaagaagaa agacttcgta
    25801 tcattgatgg tcgagatagg gcccagctgt atgtcgatgg tcagtgggtt aaaactcaat
    25861 atcagacaga gattggggaa gatatttttt atcaaggtaa aaagaaaggg ctatctaggt
    25921 tagatatctt gatagaaaat atggggcgtg tcaactatgg gcataagttc ttagcggata
    25981 cgcaacgtaa gggaattcgg acaggggtct gtaaggatct gcatttctta ctaaactgga
    26041 aacactatcc actcccacta gacaatcctg agaaaattga tttttcaaaa ggatggactc
    26101 aaggacaacc agccttttac gcttatgact ttacagtcga agagccaaaa gatacttacc
    26161 tagacttgtc tgagtttggt aagggggttg cctttgtcaa tgggcagaat ctaggacgtt
    26221 tttggaacgt tggcccaact ctctcacttt atatccctca tagctatctc aaggaaggtg
    26281 ccaaccgcat cattatcttt gaaacagaag gtcaatataa agaagagatt catttaactc
    26341 gtaaacctac actaaaacat ataaaggggg aaaacttatg acaattgtag gatgccgtat
    26401 tgatggacgt ttgatccacg gacaagtagc caatctttgg gctggaaaac taaatgtttc
    26461 acgcattatg gttgtagacg acgaagttgt caacaacgat attgaaaaga gtggtttgaa
    26521 acttgcgaca ccaccaggtg tgaaattgag tattttgcca gttgagaaag ctgcagccaa
    26581 tattcttgct ggtaaatacg atagccaacg tctctttatc gtggctcgta aaccagaccg
    26641 cttccttggt ttggtagaag caggtgtacc acttgaaacc cttaatgttg ggaatatgtc
    26701 tcaaacacca gaaacacgtt ctattacacg ttctatcaac gtagtagaca aggatgtgga
    26761 agacttccac aaactggcag aaaaaggtgt taaacttact gctcagatgg ttccaaatga
    26821 tccaatttca gactttttga gcttattaaa ataggaaaaa aatttttagg aggtcattgt
    26881 tatgatacaa tggtggcaaa ttttacttct cactttgtac tcagcttatc aaatctgtga
    26941 tgagttgacg atcgtttcat ctgcaggttc tcctgtattt gctggtttca ttactggttt
    27001 aatcatggga gatgtgacta ctggtttact tatcggtggt aacttgcaac tgttcgttct
    27061 tggggttggt accttcggtg gtgcttctcg tatcgacgca acttctggtg cggttcttgc
    27121 gacagccttc tctgtttcac aaggaattga tgcaccgctt gccattacta caatcgctgt
    27181 accagtagca gctctcttga cttacttcga cgttcttggt cgtatgacta ctaccttctt
    27241 cgctcaccgt gtggatgctg caatcgaacg ctttgactat aaaggtattg aacgcaacta
    27301 cttgcttggt gcgattccgt gggctctatc tcgtgccctt ccagtcttct ttgcccttgc
    27361 ttttggtggt gcctttgtac aatcagtagt agacttcgtt gaagcctaca aatgggttgc
    27421 agatggcttg acactcgcag gacgtatgct tccaggtctt ggatttgcaa tcttgcttcg
    27481 ttaccttcca gttaaacgta accttcacta ccttgctatg ggatttggtt tgacagctat
    27541 gttgactgtt ctttactcat atgtaacagg tcttggtggc gctgttgctg gtatcgtagg
    27601 tactcttcct gctgaagttg ctgaaaaaat tggtttcgtg aacaacttca aaggtttgtc
    27661 tatgattggt atttctatcg taggtatttt ccttgcagtg cttcacttca aaaatagcca
    27721 aaaagtagct gtagcagcac cttctacacc atcagaaagt ggggaaatcg aagatgacga
    27781 attctaatta caaacttaca aaagaagatt ttaatcaaat caacaaacgt agcttgttta
    27841 ctttccaatt aggttggaac tacgaacgta tgcaagcttc tggttacctt tacatgatct
    27901 tgcctcagtt gcgtaaaatg tatggtgatg gaactcctga attgaaagaa atgatgaaag
    27961 ttcatactca attcttcaat acttcaccat tcttccatac cattatcgct ggttttgacc
    28021 ttgccatgga agaaaaagat ggtgtaggtt caaaagacgc tgttaacggt atcaagacag
    28081 gtttgatggg accattcgct cctcttgggg atacaatctt tggttcactt gtacctgcta
    28141 tcatggggtc agtcgcagca actatggcta tcgctggcca accttggggg atcttccttt
    28201 ggattgcagt tgcagtagcg tatgacatct tccgttggaa acagttggaa tttgcttaca
    28261 aagaaggggt taaccttatc aacaacatgc aaagtacctt gacagctttg attgacgctg
    28321 catctgtact tggtgtcttc atgatgggtg ctcttgtagc aacagtgatt aactttgaaa
    28381 tttcttacaa gttgccaatc ggtgaaaaga tgattgattt ccaagacatc ttgaaccaaa
    28441 tcttcccacg tttgcttcca gcaatcttta ctgcctttat cttctggttg cttggtaaaa
    28501 aaggtatgaa ctctactaaa gctatcggta ttattatcgt acttgctttg gctctttctg
    28561 cccttggtca ctttgcactt ggaatgtaat tccttatgac taaatcatta attttggtga
    28621 gccatggtcg cttctgtgag gagcttagag gtagcacaga aatgattatg ggcccacaag
    28681 acaacattta cacagtagct cttcttccag aagatggccc agaagaattt actgctaaat
    28741 ttgaagctgt tattgaagga ttggatgatt tcctagtctt tgcggatctt ctcggtggga
    28801 caccttgtaa tgtggtgagt cgcttgatca tggaaggtcg tgatattgac ctttacgcag
    28861 ggatgaatct tccaatggtg attgaattta tcaatgcgag ccttacaggc gcagatgcgg
    28921 actacaagag ccgtgctgca gaaagcattg tgaaagttaa tgacctgtta gcgggcttcg
    28981 atgatgacga agatgaataa tactcttcga aaatctcttc aaactacgtc aacgtcgcct
    29041 tgccgtaggt atatgttact gacttcgtca gtcttatccg gcaacctcaa aacggtgttt
    29101 tgagctgact tcgtcagtct tatccggcaa cctcaaagca gtgctttgag cagcctgcgg
    29161 ctagtttcct acagatttta gttggaactc gattcaattc atgtgacaac gtgaaaatcg
    29221 ttagagcatt ttatatagaa tatacatggg aatggagctt actcccattc ccatatttaa
    29281 tagaaaaaga ggaactcaat gctacattat acaaaagaag acttgctcga attgggtgca
    29341 gaaatcacta cgcgtgaaat ctaccaacag cctgatgtat ggagagaagc ttttgaattt
    29401 tatcaagcaa aacgtgaaga aattgcagcc tttctacaag aaatcgctga taaacatgac
    29461 tatattaagg ttatcttgac aggtgctggg acttctgctt atgtgggaga taccttgcta
    29521 ccttacttta aggaagtcta tgacgaacgc aaatggaatt tcaatgctat tgcgacaaca
    29581 gatatcgttg ccaaaccagc aacctatttg aaaaaagatg tggcaactgt ccttgtgtct
    29641 tttgctcgta gtgggaactc gcctgaaagt gtggcgactg ttgatttggc caaatccttg
    29701 gtggatgagc tttatcaagt gacgattact tgtgcagcag atggtaaatt ggctcttcaa
    29761 gctcacggtg atgaccgtaa tctcttgctc ttgcaaccag ctgtctctaa tgatgctgga
    29821 tttgccatga cttctagctt tacgtctatg atgttgacaa ctctcttggt ctttgatcct
    29881 acagaatttg ctgttaagtc tgaacgtttt gaagttgtat ctagtcttgc ccgtaaagtt
    29941 ttagacaagg cagaagatgt caaagagctc gttgatttag actttaaccg tgtcatctat
    30001 ctaggcgctg gtcctttctt tggacttgct catgaagctc agctcaagat tttggaatta
    30061 actgctggtc aagttgcgac catgtatgaa agcccagttg gcttccgtca cggtccaaaa
    30121 tctcttatca acgacaatac agttgttttg gtctttggta caacgacgga ctacactcgt
    30181 aagtacgact tggacttggt tcgtgaagtt gctggtgacc agattgctcg tcgtgttgtg
    30241 cttttgagtg atcaagcttt tggtcttgaa aatgtcaaag aagtggtcct tggttgtggc
    30301 ggtgtcttga atgatattta ccgtgtcttc ccttacatcg tttatgccca actctttgcc
    30361 ctattgactt cactcaaggt agaaaataaa ccagatacac cgtctcctac aggtacagta
    30421 aaccgtgtag tacaaggtgt cataattcac gaatatcaaa agtaagacag tgtttatgaa
    30481 ttcttgacaa gaggatttgt aaattatcag ataaaccata gattgtcagt acgctttcta
    30541 tggtttgttt gcttgagaga aatagtaaaa ggagaacaga atgaaagcat acacagagcg
    30601 tgtatttgga aatgttgagg gtgaggatgt cttggcctat cgatttgaga cagacggtgg
    30661 ctaccaactt gaggttatga cttatggtgc gactatcttg cgctatgtcg cacctgacaa
    30721 ggctggaaat tttgccaatg ttatcttggg atttgatgac tttgatagtt atgtaggcaa
    30781 tagtcccaag catggagcaa gtgtaggtcc tgtagcgggt cgtattgcag gtgcgacctt
    30841 tgagctcaat ggtaagacct atgaccttga ggttaataat gctagcaact gtaatcacag
    30901 tggttcaact ggttgggatt ccagcttgtt tgaagttgaa gaagtaagcg atcatggctt
    30961 gactctctac acagagcgta cagatgggac aggagggttc cctggaaatc tcaagatttg
    31021 gatcagttat cacttggaag aaactggtgc ctatgaaatc agctacaagg taacgaccga
    31081 tcaggatacg ctggtcaatc caaccaacca cagctatttc aacttgtctg gtgatttcac
    31141 gcagacgatt gaccgtcatg tcttccaact aaacacagag ggcatttact caatcgctcc
    31201 tgacggtgtt cctgccaaaa ctccagaagc caaccgtgat gtggtcaaac acatctacaa
    31261 tggtgccttg ttgaaggata tctttgcaga agaagatgag caaatccagc tggcatcagg
    31321 tttggatcat ccatttgccc ttcctgcagg ccatgacaat gctggattcc tttatgacca
    31381 aaattcaggt cgcttcctgc ttttcaagac agaagctcct tgctttgtgg tctacacagc
    31441 aaactttgtg gatgaaagtg tcatcatagg aggtcagcca atgctacagc acaatgggat
    31501 tgctcttgaa gcgcaagctt taccagatgc cattcacagt gaccttaaag gccaagtcat
    31561 tcttaaagct ggtcaaacct tcaccagtaa gacacgttat gaacttgttg tgaaataaaa
    31621 aaagctggtc aaaaagtctt taaaattaaa ataacgcata ttgtcaggtg atgaaaagtt
    31681 tgataatatg cgttttatta tgaaatgatt tactttatat tatcctgaaa tggtgttatt
    31741 tttgagttat ctggcttgac tttcttgatg gaaattatat aatagttgta acaatgataa
    31801 ttacaactag aaaagaggac catttatgac ctatgaatac aagagtcaca tttatttggc
    31861 agagacagct ttaaatgtaa aggatttggc cagtcaaaca gccttttatc agcaagttat
    31921 tggtttagaa atcttatctc aaactgagac agagtccatt ctaggccttg gtggaaaagt
    31981 cttggtacag ctgattcaag cacaagagag cggagaagtg agggaatatt atggtcttta
    32041 ccatttggcc attctcttgc ccacacgcaa ggctttagct gatgtcttga aacacctgac
    32101 agatttacaa attcctcttg tcggcggtgc agaccatggt tacagtgaag ctatttactt
    32161 ggaagatttg gagggaaatg gcattgaact ctatcgagat aagccagttt ccacatggga
    32221 tattcgagaa gatggacgca ttatcggagt gacagaggct cttgcggcgc aggacattta
    32281 tgagttgggg gaaagagtag agccctttat cctggcagaa ggtacgagaa tggggcatat
    32341 tcatctttcc gtcaaggata gtcgaaagtc cagccagttt tatcaaaagg tgttagggct
    32401 agaggataaa ttcagtgtgc ctagcgctag ttggattgcg gctggagatt accatcatca
    32461 tttagcagtt aacgaatggg gaggaaaagg tctggcttcg cgtaagcaag gcttaccagg
    32521 tttagcctac tatgtcatcg aagtcgcaca caaaaaagaa ctattaacga ttgcccaacg
    32581 agcacaagaa gttgacgcac caatcaaatg gatgacatcg agccaattgg aaatcacaga
    32641 ctcagatggc atcgtgaccc gtattcgttt agcaaggtaa aattaggaat ttttaataag
    32701 ttataagtat tgctagtttg ctttttgaac ggtctttggt aacagaactg cgtgagctgg
    32761 atgggcgaga attttgacaa agaagctgat tagagatata atgaagaaaa atcgagcaag
    32821 gaaaaagaaa tgacaaattc aaagtatatt acttgtttga aacgttcaga gggccagttg
    32881 tgtgggattc aaaagatgat tgaaggagat cgtgactgtg ctgatattgt gacgcaactg
    32941 acagcagtga gatctagtgt agagcgcgtg attgagatga taattaccga aaatcttact
    33001 gaatgtatca atcagccact agatgattct gaagctcaaa aggaacgctt agaaaaggct
    33061 atccgatact tgattaaacg gaaataaatg aatgttttga gacgatatgt gcaaaggtct
    33121 attaactatt agaatagttt aatgggagtc aaaagaagtt gtaaaaaatc tttaaaatta
    33181 aaaaaacgca tagtatcagg tattgaaatg tactgacccc aaaaagttag attttttctg
    33241 tctaactttt ggggtgcagt tcataagaac cttggtaata tgcgttttat tatggggaga
    33301 tttatacttt tcgaaaatct cttcaaacca ggtcagcttc accttgccgt agatatggtt
    33361 actgacttcg tcagttctat ccacaacctc aaaacagtgt tttgagctga cttcgtcagt
    33421 tccatccaca accttaaaac agtgttttga gctgacttcg tcagttccat ccacaacctt
    33481 aaaacagtgt tttgagcagc ctgcggctaa cttcctagtt tgcactttaa ttttcattga
    33541 gtattacttc atcttctcat gaaattgagt ttttgcccag ttcctcttga ttattctact
    33601 tgaccaggcc aagcattcat accaccttct acgttggtaa cggtgaggcc ttgggagatg
    33661 agaaattggc aggtagatgc agagcggact cctccttgac aaataacata gtattcatgg
    33721 tcaggtttga gttctttgta gccttgctct aaggtactta atggaagatt tttggcacct
    33781 ggtgcatgtc ctgcttggaa ttcatgtgct tcacggacat cgataagttc tagattttca
    33841 ttttggtatt ttccataaaa gtcagccatg ctgatactag tttccatatt ctactccttc
    33901 tgggttaacc attttgtata gtgaataagc gccgtcaagg ttttgggcgg taaatcctgc
    33961 ttgcttgagg ataggctctg cgatatagct gcgcaaacca ctgtggcagc tgacgatgta
    34021 ggcttgtttt ttgtccagtt catcagcttc ctccttgaca ctttgtcagt ttttgataca
    34081 atagtacaaa attagaggag gtgggctatg attcagaaac atgcgattcc tattttagag
    34141 tttgatgaca atcctcaggc ggttatcatg cccaatcacg aggggctgga cttgcagttg
    34201 ccaaagaagt gtgtttatgc atttttagat gaggagattg accgctatgc aagggaagta
    34261 ggggcggatt gtgtcggcga attcgtttct gctaccaaga cctatccagt ctatgtcatc
    34321 aactacaagg gtgaggaggt ctgtctggct caggctcctg ttggctccgc tccagcagcc
    34381 cagtttatgg attggttgat tggctatggt gtggagcaga ttatctctac tgggacctgt
    34441 ggtgttctag ctgatataga ggaaaatgcc tttctagtcc ctgttcgcgc tctgcgagat
    34501 gaaggagcca gttaccacta tgtggcacct tctcgttata tggaaatgca gccagaggct
    34561 attgctgcta ttgaggaagt tttggaagac agagggattc cttatgaaga agtcatgacc
    34621 tggacgacag acggttttta ccgagaaacg gctgaaaagg tggcttatcg taaggaagaa
    34681 ggctgtgctg ttgtggagat ggagtgttct gctcttgcgg cagtagctca attgcgtggg
    34741 gttctctggg gtgaattgtt gttcacagca gattctctag cggacttgga ccagtacgac
    34801 agtcgtgact ggggctcgga agcttttaat aaggcgctag aactgagttt agcaagtgtt
    34861 caccaccttt agttgtactg gcaaaggatt tgttttatca taaaatgtct agctcatact
    34921 tttcaaaaat atgtttaaac gaggtcacct tcctcttgtc ctaagcatgt tgaggttggg
    34981 aaaaatcttt aaaatcagaa aaacgtatca tatcaggtga tgaaaacctt gatactatgc
    35041 gttttatgtt ggtaagattt agagtgagat gaaatgatac tcttcgaaaa tcttttcaaa
    35101 ccaggtcagc ttcaccttgc cgtaggtata tgttactgac ttcgtcagtc ttatccggca
    35161 acctcaaaac ggtgttttga gctgacttcg tcagttctat ttgcaacctc aaaacagtgt
    35221 tttgagcaat ctgtgactag ctttctaatc gatgccttgg ttctcattgc ctataatcaa
    35281 aaagagaaat tttctcctga aaagcatata gagtagctgg cgttaaaagc tcctgtcttg
    35341 cttttttgac ctatagtcac atctatcaag tattgttctt gcctaagcta tcaataaaaa
    35401 ggtggcattt tttaggcttg gtgttagtag attttgcctt atcctatcta agtcatttcg
    35461 aactttttat ggtacaatgg aaacatgtta ttcaaattat ctaaggaaaa aatagagcta
    35521 ggcttatctc gtttatcgcc agcccgtcgt atttttttga gttttgcctt ggtcatttta
    35581 ctaggctctc ttcttttgag cttgcccttt gtccaagttg aaagctcacg agcgacttat
    35641 tttgatcatc ttttcactgc tgtctctgca gtctgtgtga caggtctctc aacccttcca
    35701 gtagctcaca cctataatat atggggccaa ataatctgtt tgctcttgat tcagatcggt
    35761 ggtctagggc tcatgacctt tattggggtt ttctatatcc agagcaagca aaagcttagt
    35821 cttcgtagcc gtgcaactat tcaggatagt tttagttatg gagaaactcg atctttgaga
    35881 aagtttgtct attctatttt tctcacgacc tttttggttg agagcttggg agctattttg
    35941 cttagttttc gccttattcc tcaacttggc tggggacgtg gtctttttag ttccattttt
    36001 ctagcgatct cagccttctg taatgccggt tttgataatt tagggagcac cagtttattt
    36061 gcttttcaga ccgatttact ggtcaatctg gtgattgcag gcttgattat tacaggcggc
    36121 cttggtttta tggtctggtt tgatttggct ggtcatgtag gaagaaagaa aaaaggacgt
    36181 ctgcactttc atacgaagct tgtactattg ttgactatag gtttgttgtt atttggaacg
    36241 gcaactactc tctttcttga gtggaacaat gctggaacga ttggcaatct ccctgttgcc
    36301 gataaggttt tagttagctt ttttcaaaca gtgacgatgc gaacagctgg cttttctacg
    36361 atagattata ctcaggctca tcctgtgact cttttgattt atatcttaca gatgtttcta
    36421 ggtggggcac ctggaggaac agctggggga ctcaagatta cgacattttt tgtcctcttg
    36481 gtctttgcac gaagtgagct tctaggcttg cctcatgcca atgttgcgag acgaacgatt
    36541 gcgccgcgaa cggttcaaaa atcctttagt gtctttatta tctttttgat gagcttcttg
    36601 ataggattga ttctgctagg gataacagcc aaaggcaatc ctccctttat ccacctcata
    36661 tttgaaacca tttcagctct tagtacagtt ggtgtaacgg caaatctgac tcctgacctt
    36721 gggaaattgg ctctcagtgt tatcatgcca cttatgttta tgggacgaat tggtcccttg
    36781 accttgtttg ttagcttggc agattaccat ccagaaaaga aagatatgat tcactatatg
    36841 aaagcagata ttagtattgg ttaagaaagg aaagagcatg tcagatcgta cgattggaat
    36901 tttgggcttg ggaatttttg ggagcagtgt cctagctgcc ctagccaagc aggatatgaa
    36961 tattatcgct attgatgacc acgcagagcg catcaatcag tttgagccag ttttggcgcg
    37021 tggagtgatt ggtgacatca cagatgaaga attattgaga tcagcaggga ttgatacctg
    37081 cgataccgtt gtagtcgcga caggtgaaaa tctggagtcg agtgtgcttg cggttatgca
    37141 ctgtaagagt ttgggggtac cgactgttat tgctaaggtc aaaagtcaga ccgctaagaa
    37201 agtgctagaa aagattggag ctgactcggt tatctcgcca gagtatgaaa tggggcagtc
    37261 tctagcacag accattcttt tccataatag tgttgatgtc tttcagttgg ataaaaatgt
    37321 gtctatcgtg gagatgaaaa ttcctcagtc ttgggcaggt caaagtctga gtaaattaga
    37381 cctccgtggc aaatacaatc tgaatatttt gggtttccga gagcaggaaa attccccatt
    37441 ggatgttgaa tttggaccag atgacctctt gaaagcagat acctatattt tggcagtcat
    37501 caacaaccag tatttggata ccctagtagc attgaattcg taaagaggga tgacccctct
    37561 tttttgatgc ccaagatggc aaatagagac agaagcccct tgtcttctag taaaagttct
    37621 tcaaaggctg gactttatgg taaaatagaa ggaagtgaca agagagagta atactcaatg
    37681 aaaatcaaag atcaaactag gaaactagct gcgggctgct caaaacactg ttttgaggtt
    37741 gtggatagaa ctgacgaagt cagctcaaaa cactgttttg aggttgcaga tagaactgac
    37801 gaagtcagta acatctatac ggcaaggcga cgttgacgcg gtttgaagag attttcgaag
    37861 agtataagaa aaaatcagtc ccctaaagga gcagattatg aagttattgt ctatcgccat
    37921 ttctagctat aatgcagcag cctatcttca ttactgtgtg gagtcgctag tgattggtgg
    37981 tgagcaagtt gggattttga ttatcaatga cgggtctcag gatcagactc aggaaatcgc
    38041 tgagtgttta gctagcaagt atcctaatat cgttagagcc atctatcagg aaaataaatg
    38101 ccatggcggt gcggtcaatc gtggcttggc agaggcttct gggcgctatt ttaaagtagt
    38161 tgacagtgat gactgggtgg atcctcgtgc ctacttgaaa attcttgaaa ccttgcagga
    38221 acttgagagc aagggtcaag aggtggatgc ctttgtgacc aattttgtct atgaaaagga
    38281 aggtcagtct cgtaagaaga gtatgagtta cgagtcagtc ttgcctgttc ggcagatttt
    38341 tgactaggac caggtcggaa atttctccaa aggccagtat atcatgatac actcgctgat
    38401 ttatcggaca gatttgttgc gtgctagcca gttctaactg cctgaacata ctttttatgt
    38461 cgatgatctc tttgtcttta cgccccttca gcaggtcaag accatgtact atctgcctgt
    38521 cgatttctat cgttatttga ttgggcgtga ggaccagtct gtcaatgagc aagtgatgat
    38581 taagcgcatt gaccagcaac tcaaggtcaa tcgactcttg gtagaccagc ttgatttgtc
    38641 ccaagtgagt catcctaaaa tgcgagaata tctgctgaat catattgaaa tcacgacggt
    38701 gatttccagt accctgctca accgatctga aacagcggag catctggcaa aaaaacgcca
    38761 attgtggacc tatattcagc agaaaaatcc agaagtcttt caggctattc gtaagaccat
    38821 gttgagccgt ttgaccaaac attctgtctt gccagatcgc aaactgtcca atgtcgtcta
    38881 tcaaatcacc aaatctgttt atggatttaa ttaatataag tgttttataa gagggattta
    38941 agaaaaattt taactttttc ttagtccttt ttaatttcag gagattatac tagagtcatc
    39001 aaataaagaa agactctaag gagaatccta tgaaattcaa tccaaatcaa agatatactc
    39061 gttggtctat tcgccgtctc agtgtcggtg ttgcctcagt tgttgtggct agtggcttct
    39121 ttgtcctagt tggtcagcca agttctgtac gtgccgatgt ggtcaatccg accccaggtc
    39181 aagtcttacc tgaagagaca tcgggaacga aagagggtga cttatcagaa aaaccaggag
    39241 acaccgttct cactcaagcg aaacctgagg gcgttactgg aaatacgaat tcacttccga
    39301 cacctacaga aagaactgaa gtgagcgagg aaacaaactc ttctagtctg gatacacttt
    39361 ttgaaaaaga tgaagaagct caaaaaaatc cagagctaac agatgtctta aaagaaactg
    39421 tagatacagc tgatgtggat gggacacaag caagtccagc agaaactact cctgaacaag
    39481 taaaaggtgg agtgaaagaa aatacaaaag acagcatcga tgttcctgct gcttatcttg
    39541 aaaaagctga agggaaaggt cctttcactg ccggtgtaaa ccaagtaatt ccttatgaac
    39601 tattcgctgg tgatggtatg ttaactcgtc tattactaaa agcttcggat aatgctcctt
    39661 ggtctgacaa tggtactgct aaaaatcctg ctttacctcc tcttgaagga ttaacaaaag
    39721 ggaaatactt ctatgaagta gacttaaatg gcaatactgt tggtaaacaa ggtcaagctt
    39781 taattgatca acttcgcgct aatggtactc aaacttataa agctactgtt aaagtttacg
    39841 gaaataaaga cggtaaagct gacttgacta atctagttgc tactaaaaat gtagacatca
    39901 acatcaatgg attagttgct aaagaaactg tcgaaaaagc tgttaaagat aacgttaaag
    39961 acagtatcga tgttccagca gcctacctag aaaaagccaa gggtgaagg
//
LOCUS       DAVBDR010000012        39718 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.012, whole genome shotgun sequence.
ACCESSION   DAVBDR010000012 DAVBDR010000000
VERSION     DAVBDR010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 39718)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39718)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39718
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.012"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            <1..179
                     /locus_tag="VQ540_000657"
     CDS             <1..179
                     /locus_tag="VQ540_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="choline-binding protein D"
                     /protein_id="HET2544503.1"
                     /translation="TGWVKDGDTWYYLEASGAMKASQWFKVSDKWYYVNGLGALAVNT
                     TVDGYKVNANGEWV"
     gene            580..1701
                     /gene="mnmA"
                     /locus_tag="VQ540_000658"
     CDS             580..1701
                     /gene="mnmA"
                     /locus_tag="VQ540_000658"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HET2544504.1"
                     /translation="MSDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVVAVADQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMTLGADYVATGHYARVARDEDGTVHMLRGVDNGKDQTYFLSQLS
                     QEQLQKTMFPLGHLEKPEVRRLAEEAGLSTAKKKDSTGICFIGEKNFKNFLSNYLPAQ
                     PGRMMTVDGRDMGEHAGLMYYTIGQRGGLGIGGQHGGDNAPWFVVGKDLSKNILYVGQ
                     GFYHDSLMSTSLEASQVHFTREMPEEFTLECTAKFRYRQPDSKVTVHVKGDKAEVIFA
                     EPQRAITPGQAVVFYDGEECLGGGLIDNAYRDGQVCQYI"
     gene            1842..2297
                     /locus_tag="VQ540_000659"
     CDS             1842..2297
                     /locus_tag="VQ540_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HET2544505.1"
                     /translation="MTQQDFRTKVDNTVFGVRATALIVQNHKLLVTKDKGKYYTIGGA
                     IQVNESTEDAVVREVKEELDVKAQAGQLAFVVENRFEVDGVSYHNIEFHYLVDLLEDA
                     PLTMQEDEKRQPCEWIDLDKLQNIQLVPAFLKTALPDWEGQLRHIHLEE"
     gene            2307..4220
                     /gene="mnmG"
                     /locus_tag="VQ540_000660"
     CDS             2307..4220
                     /gene="mnmG"
                     /locus_tag="VQ540_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HET2544506.1"
                     /translation="MTYHFTEEYDIIVIGAGHAGVEASLAASRMGCKVLLATINIEML
                     AFMPCNPSIGGSAKGIVVREVDALGGEMAKTIDKTYIQMKMLNTGKGPAVRALRAQAD
                     KELYSKEMRKTVENQENLTLRQTMIDEILVEDGKVVGVRTATHQEYAAKAVIVTTGTA
                     LRGEIIIGDLKYSSGPNHSLASINLADNLKELGLEIGRFKTGTPPRVKASSINYDVTE
                     IQPGDEVPNHFSYTSRDEDYVKDQVPCWLTYTNGTSHEIIQNNLHRAPMFTGVVKGVG
                     PRYCPSIEDKIVRFADKERHQLFLEPEGRNTEEVYVQGLSTSLPEDVQRDLVHSIKGL
                     ENAEMMRTGYAIEYDMVLPHQLRATLETKKISGLFTAGQTNGTSGYEEAAGQGIIAGI
                     NAALKIQGKPELILKRSDGYIGVMIDDLVTKGTIEPYRLLTSRAEYRLILRHDNADMR
                     LTEMGREIGLVDDERWARFEIKKNQFDNEMKRLDSIKLKPVKETNAKVEEMGFKPLTD
                     AVTAKEFLRRPEVSYQDVVAFIGPAAEDLDDKIIELIETEIKYEGYISKAMDQVAKMK
                     RMEEKRIPANIDWDDIDSIATEARQKFKLINPETIGQASRISGVNPADISILMVYLEG
                     KNRSISKTLQKSK"
     gene            4409..4498
                     /locus_tag="VQ540_000661"
                     /pseudo
     CDS             4409..4498
                     /locus_tag="VQ540_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(4644..6323)
                     /locus_tag="VQ540_000662"
     CDS             complement(4644..6323)
                     /locus_tag="VQ540_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HET2544507.1"
                     /translation="MAYTLKPEEVGVFAIGGLGEIGKNTYGIEYQDEIIIVDAGIKFP
                     EDDLLGIDYVIPDYSYIVDNIDRVKAVLITHGHEDHIGGIPFLLKQANVPIYAGPLAL
                     ALIRGKLEEHGLLRNAKLYEINHNTELTFKNLKATFFRTTHSIPEPLGIVIHTPQGKI
                     VCTGDFKFDFTPVGEPADLHRMAALGEEGVLCLLSDSTNAEVPTFTNSEKVVGQSIMK
                     IIQGIEGRIIFASFASNIFRLQQATEAAVKTGRKIAVFGRSMEKAIVNGIDLGYIKAP
                     KGTFIEPNEIKDYPAGEVLILCTGSQGEPMAALSRIANGTHRQVQLQPGDTVIFSSSP
                     IPGNTTSVNKLINIISEAGVEVIHGKVNNIHTSGHGGQQEQKLMLRLIKPKYFMPVHG
                     EYRMQKVHAGLAVDTGVEKDNIFIMSNGDVLALTADSARIAGHFNAQDIYVDGNRIGE
                     IGAAVLKDRRDLSEDGVVLAVATVDFKSQMILSGPDILSRGFVYMRESGDLIRQSQRI
                     LFNAIRIALKNKDASVQSVNGAIVNAIRPFLYENTEREPIIIPMILTPDEE"
     gene            complement(6325..6558)
                     /locus_tag="VQ540_000663"
     CDS             complement(6325..6558)
                     /locus_tag="VQ540_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HET2544508.1"
                     /translation="MIYKVFYQETKERSPRRETTRALYLDIDASSELEGRITARQLVE
                     ENRPEYNIEYIELLSDKLLDYEKETGAFEITEF"
     gene            6940..7161
                     /locus_tag="VQ540_000664"
     CDS             6940..7161
                     /locus_tag="VQ540_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000184674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2544509.1"
                     /translation="MTNQVLEENYLCDSLLAFSPPRDLCRLVCILLWIKCLDALLMLG
                     FFVWGCRDSRFTTRKFHPIYQDEVVFAFF"
     gene            complement(7374..7526)
                     /gene="cibB"
                     /locus_tag="VQ540_000665"
     CDS             complement(7374..7526)
                     /gene="cibB"
                     /locus_tag="VQ540_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000977347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibB"
                     /protein_id="HET2544510.1"
                     /translation="MMKDLNNCREISNKELQEIKGGFGVGVGIALFMAGYTIGKDLRK
                     KFGKSC"
     gene            complement(7528..7713)
                     /gene="cibA"
                     /locus_tag="VQ540_000666"
     CDS             complement(7528..7713)
                     /gene="cibA"
                     /locus_tag="VQ540_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000180803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibA"
                     /protein_id="HET2544511.1"
                     /translation="MTNFDILDNQFLSLSENELSDIDGGLAPLVIFGVAVSWKAIAGG
                     TALIGSGLAAGYFLGGD"
     gene            7891..8574
                     /gene="tsaB"
                     /locus_tag="VQ540_000667"
     CDS             7891..8574
                     /gene="tsaB"
                     /locus_tag="VQ540_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000865689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HET2544512.1"
                     /translation="MKVLAFDTSSKALSLAILEDKQVLAETTINIKKNHSITLMPAID
                     FLMESLDWTPKDLDRIVVAEGPGSYTGLRIAVATAKTLTHTLNIELVGMSSLLALVPY
                     QQEGLFVPLMDARRNNVYAGFYENAKPVMPEAHLSFEEVLEKVKGASQVTFVGEVGPF
                     VEQIQEHLPRTNYKETLPNAANLALLAWDKEADSLHDFVPNYLKRVEAEENWLKNHTE
                     SGESYIKRL"
     gene            8571..9008
                     /gene="rimI"
                     /locus_tag="VQ540_000668"
     CDS             8571..9008
                     /gene="rimI"
                     /locus_tag="VQ540_000668"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HET2544513.1"
                     /translation="MIEIKRIQQQPDLAQAIYAVMAAVYLVSPWTLEQIQADLSQDQT
                     WYALAYDGAEVIGFLAVQENLFEAEVLQIAVKGAYQGQGIASALFAQLPTDKEIFLEV
                     RKSNQRAQAFYKKEKMAVIAERKAYYHDPVEDAIIMKREIDEG"
     gene            8998..10008
                     /gene="tsaD"
                     /locus_tag="VQ540_000669"
     CDS             8998..10008
                     /gene="tsaD"
                     /locus_tag="VQ540_000669"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HET2544514.1"
                     /translation="MKDRYILAFETSCDETSVAVLKNDDELLSNVIASQIESHKRFGG
                     VVPEVASRHHVEVITACIEEALAEAGITEEDVTAVAVTYGPGLVGALLVGLSAAKAFA
                     WAHGLPLIPVNHMAGHLMAAQSVEPLEFPLLALLVSGGHTELVYVSEAGDYKIVGETR
                     DDAVGEAYDKVGRVMGLTYPAGREIDELAHQGQDIYDFPRAMIKEDNLEFSFSGLKSA
                     FINLYHNAEQKGESLSTEDLCASFQAAVMDILMAKTKKALEKYPVKTLVVAGGVAANK
                     GLRERLAAEITDVKVIIPPLRLCGDNAGMIAYASVSEWNKENFAGWDLNAKPSLAFDT
                     ME"
     gene            complement(10054..11354)
                     /locus_tag="VQ540_000670"
                     /pseudo
     CDS             complement(10054..11354)
                     /locus_tag="VQ540_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677188.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(11630..11981)
                     /locus_tag="VQ540_000671"
                     /pseudo
     CDS             complement(11630..11981)
                     /locus_tag="VQ540_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(12088..12380)
                     /locus_tag="VQ540_000672"
                     /pseudo
     CDS             complement(12088..12380)
                     /locus_tag="VQ540_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            12623..13829
                     /locus_tag="VQ540_000673"
                     /pseudo
     CDS             12623..13829
                     /locus_tag="VQ540_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200043.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
     gene            13822..14470
                     /locus_tag="VQ540_000674"
                     /pseudo
     CDS             13822..14470
                     /locus_tag="VQ540_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397244.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
     gene            14480..16096
                     /locus_tag="VQ540_000675"
     CDS             14480..16096
                     /locus_tag="VQ540_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2544515.1"
                     /translation="MYTIIKSNIKKFSLLTIFIVAGQLLLIYAATINALVLNELIAMN
                     LERFLKLSIYQMIVWCGIIFLDWVVKNYQVEVIQEFNLEIRNRVATDISNSTYQEFHS
                     KSSGTYLSWLNNDVQTLNDQAFKQLFLVIKGISGTIFAVVTLNHYHWSLTVATLFSLM
                     IMLLVPKIFASKMREVSLNLTNQNEAFLKSSETILNGFDVLASLNLLYVLPKKIKEAG
                     ILLKMVIQRKTTVETLAGAISFFLNIFFQISLVFLTGYLAIKGIVKIGTIEAIGALTG
                     VIFTALGELGGQLSSIIGTKPIFLKLYSINPIESNKMNDIEPNEVNRDFPLYEAKNIC
                     YKYGDKEILKNLNFCFQRNEKYLILGESGSGKSTLLKLLSGFLRDYSGELRFCGDDIK
                     KTSYLNMVSNVLYVDQKAYLFEGTIRDNILLEENYTDEEILQSLEQVGLSVKDFPNNI
                     LDYYVGDDGRLLSGGQKQKITLARGLIRNKKIVLIDEGTSAIDRRTSLAIERKILDRE
                     DLTVIIVTHAPHPELKQYFTKIYQFPKDFI"
     gene            16116..16960
                     /locus_tag="VQ540_000676"
                     /pseudo
     CDS             16116..16960
                     /locus_tag="VQ540_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813546.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            17028..18529
                     /locus_tag="VQ540_000677"
                     /pseudo
     CDS             17028..18529
                     /locus_tag="VQ540_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819023.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase"
     gene            18541..19290
                     /locus_tag="VQ540_000678"
     CDS             18541..19290
                     /locus_tag="VQ540_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000069862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HET2544516.1"
                     /translation="MSDNTKYIFLSPHLDDAIFSCGDYISKLTSEGEIVLVITIFSGY
                     PLSQQLQPSAKQFHKLCNLGKYPIEERKKEDRLACERLQCDFRHLSYYECLYRKDRNG
                     NFLYRHIYSKLKNEDTLKNDIIKELLMHLDDKCVVYCPLSLGDHVDHVFVNSIGRALE
                     FMRYKVIYYEDFPYVSDSSMVSYMGKTKELKMYQEELDEKHYIDRISSILCYKSQILI
                     IWKSVEKLLNNIKELYLRNGAAYSIRFWIKK"
     gene            19303..20475
                     /locus_tag="VQ540_000679"
     CDS             19303..20475
                     /locus_tag="VQ540_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HET2544517.1"
                     /translation="MNIAVIGLGHVGLAYALLFASKYKVVAYDIDSVKINNLKKGTLP
                     SKNEELMKFFCENNLNITFFDTFSEIKNNIDYYIIALPTDYDEKIGSFNTYEIEQTVS
                     KILRVKPNGKIILKSTVPIGFSNKLKRLFDTKNIIFVPEFLREGCSIYDNLYPSRIVV
                     GDETVEGRKIAELFLSISTHSTANIKNVMLVSPTEAEAIKLFSNTFLALRVAFFNELD
                     SFAERRSLNAEVVIKGVCLDPRIGNFYNNPSFGFGGYCLPKDTRQLKKEFIEINAPVI
                     EAIDISNTNRKQFIVKQILERKPKIVGIYKLGMKYNSDNYKESAILSIINELLIVGIK
                     ILVYEPNLNVSIDNVIFEKNFELFIKQSDLIVANRWDRGLEAYKDKVYTRGIWIRD"
     gene            20870..21733
                     /locus_tag="VQ540_000680"
     CDS             20870..21733
                     /locus_tag="VQ540_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HET2544518.1"
                     /translation="MIEKMELGEFYKELRLARKLKQSDVACAGLTASQLSKFELGQSM
                     LSADKLILAIQGINMNFDEFGHKLNNYQESPHMRIGRRVVDCFSHQDIAALEQLLEEV
                     DQEQMAQTYRRLNAIVIKNALHSLDKSYPLTEEDSEFLTTYLYAIESWTWFELYLFCN
                     TMPFLSNQDLIFLSTSLLEKSKEFKELVHNRWYMKSGYLNIISELMERKLFSYIPIFE
                     AELERMLRPYDVFEKVLWQFLKKMQIFLQTKGSNQKEIEHFIQSLQVLENPQLTALFE
                     LRLQQYKELID"
     gene            22019..22252
                     /locus_tag="VQ540_000681"
     CDS             22019..22252
                     /locus_tag="VQ540_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000933479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2544519.1"
                     /translation="MLNLQFAETMELTEAELQDVRGGNLVNSMGGGGRSGISGWGVPG
                     IYPGWGNQGMSPNRGAFDWTIDLADGLFGRRRR"
     gene            22274..22951
                     /locus_tag="VQ540_000682"
     CDS             22274..22951
                     /locus_tag="VQ540_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET2544520.1"
                     /translation="MKKMKEVKFHLATGLLILTYYLIFNVTSDLDFMVALSDNMYYVF
                     QVLLVLILGTIATIAFVKSEHWKECGRFQFRWSYLGVFLLSFFLLFVWANLTTYIFPR
                     TQNGSTVVEVATSLTGISYFVTRILYTSIIAPVSEEVVCRGLLMTSLSKVKRYYLDVL
                     VSAAIFGAMHVLQYGWITTDFIKYFGMGLIFCMMFRYTRSIYWAIALHASWNSFLLIV
                     TLLVFGY"
     gene            22963..23628
                     /locus_tag="VQ540_000683"
     CDS             22963..23628
                     /locus_tag="VQ540_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET2544521.1"
                     /translation="MKKIISHRYFIIVFLLVIADQKFSVLVLRSDLVAGLSDFAYYLS
                     DMMLNFLVVLFALIAMIWSGKWQKINSRKFKGSYLFYSFLALLAFVAWNFVTFFLFPP
                     TRNEISYQHAAPTFTGATAFLMYFFYPVIAGPIFEDMIYRGLVMTALEKGKKWGLDVL
                     GSAILFGVSHISNHGWVLTDFFVYMGGGLIFAVLFRMTKSIYWPIGLHIVYNGIGQLL
                     MLL"
     gene            23700..24926
                     /locus_tag="VQ540_000684"
     CDS             23700..24926
                     /locus_tag="VQ540_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HET2544522.1"
                     /translation="MKVFLQNRDFRQLTINQWISTLGDTIFYLAFLNYVADASFAPLA
                     ILLITISETLPQVLQIFLGVLADFQHHRVLKYTVISFTKFLLYSIVSLSLSGQSFSLL
                     LVTFICLLNLLSDTLSYFSGAMLTPIFIRIIGQDHLAEAIGFKQSTVSLVKTISNILG
                     GVLLGILSIQFISLLNALTFLIAFLGILFIKTDLLKVEKTISYQEGLSVKSFCQHLLQ
                     SSKLIWNMNKVLLVLFIISTSQAVINVTVPISTLFLRNQPFLNLQTGQSLALLATLEL
                     SALILGSLMSGYLQHTISIKIALYASLLLQLLLLVGFATAHFGLILIFSFLDAFFAGI
                     LSPRLQELVFKQIPEESMGAVQSSIGAITVVLPSLFTIALGTIATSFGTLAVSFVLLL
                     FLLVAFVMLLNIRESI"
     gene            complement(25277..25354)
                     /locus_tag="VQ540_000685"
                     /pseudo
     CDS             complement(25277..25354)
                     /locus_tag="VQ540_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            25425..26081
                     /locus_tag="VQ540_000686"
     CDS             25425..26081
                     /locus_tag="VQ540_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001141648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HET2544523.1"
                     /translation="MPTALGYVSIGLACGTIGAPYVTPVEMGLMSLFVYAGSAQFAML
                     ALIVVQAPVAAIAMTVFLINLRLFLLSLHASTYFRHTSLWYNIGMSSILTDETYGVLM
                     GELAHTDKVNPMWMHGNNLNSYVAWFVGTVVGTALGGLLPNPEIFGLDFALVGMFIGI
                     FASQFQIMQRRIPVRNLLIILAVVAVSFFLLLTVVSQSLAVLFATLLGCSMGVVLDGQ
                     "
     gene            26071..26394
                     /locus_tag="VQ540_000687"
     CDS             26071..26394
                     /locus_tag="VQ540_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000253911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HET2544524.1"
                     /translation="MVSKYLLLAVIFSDLVTWILRMIPFILVKYKGLPAIVERFLKFL
                     PVSIIFALILSSVVTGKVGSLPQIKWLDFLAVFPTAWVAFRYRNLVGTVLFGVVLIAV
                     LRLVF"
     gene            26498..27328
                     /locus_tag="VQ540_000688"
     CDS             26498..27328
                     /locus_tag="VQ540_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HET2544525.1"
                     /translation="MKKIVKYSSLAALGLVAAGVLAACSGGAKKEGQAASKKEIIVAT
                     NSSPKPFNYEENGELTGYEIEVVRAIFKDSDKYDVKFEKTEWSGVFAGLDADRYQMAV
                     NNISYTKERAEKYLYAAPTVKDPNVLVVKKDDSSIKSLDDVGGKSTEVVQGTTSAKQL
                     EDYNKQHSDNPTILNYTKANLQQIMGHLSDGQFDYKISDKITVETVIKNQGLDNLKVI
                     DLPSDQQPYVYPLLAKGQDELKTFVDKRIQELYKDGTLEKLSKQFFGDTYLPAEADIK
                     "
     gene            27369..27446
                     /locus_tag="VQ540_000689"
                     /pseudo
     CDS             27369..27446
                     /locus_tag="VQ540_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000253911.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC protein"
     gene            27550..28380
                     /locus_tag="VQ540_000690"
     CDS             27550..28380
                     /locus_tag="VQ540_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HET2544526.1"
                     /translation="MKKIVKYSSLAALALVAAGVLAACSGGAKKEGQAASKKEIIVAT
                     NGSPKPFIYEENGELTGYEIEVVRAIFKDSDKYNVKFEKTEWSGVFAGLDADRYNMAV
                     NNLSYTKERAEKYLYAAPIAQNPNVLVVKKDDSSIKSLDDIGGKSTEVVQATTSAKQL
                     EAYNAEHTDNPTILNYTKADFQQIMVRLSDGQFDYKIFDKIGVETVIKNQGLDNLKVI
                     ELPSDQQPYVYPLLAQGQDELKSFVDKRIKELYKDGTLEKLSKQFFGDTYLPAEADIK
                     "
     gene            28534..29388
                     /locus_tag="VQ540_000691"
     CDS             28534..29388
                     /locus_tag="VQ540_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000694494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HET2544527.1"
                     /translation="MKIKKWLGLAALATVAGLALAACGNSEKKADNATTIKIATVNRS
                     GSEEKRWDKIQELVKKDGITLEFTEFTDYSQPNKATADGEVDLNAFQHYNFLNNWNKE
                     NGKDLVAIADTYISPIRLYSGLNGSANKYTKVEDIPANGEIAVPNDATNESRALYLLQ
                     SAGLIKLDVSGTALATVANIKENPKNLKITELDASQTARSLSSVDAAVVNNTFVTEAK
                     LDYKKALFKEQADENSKQWYNIIVAKKDWETSPKADAIKKVIAAYHTDDVKKVIEESS
                     DGLDQPVW"
     gene            29488..30861
                     /locus_tag="VQ540_000692"
     CDS             29488..30861
                     /locus_tag="VQ540_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HET2544528.1"
                     /translation="MVFPSEQEQIEKFEKDHVVQHYFEVLRTLISKKSVFAQQVGLKE
                     VANYLGEIFKRVGAEVEIDESYTAPFVMAHFKSSRPDAKTLIFYNHYDTVPADGDQVW
                     TEDPFTLSVRNGFMYGRGVDDDKGHITARLSALRKYMQHHDDLPVNISFIMEGAEESA
                     STDLDKYLEKHADKLRGADLLVWEQGTKNALEQLEISGGNKGIVTFDAKVKSADVDIH
                     SSYGGVVESAPWYLLQALQSLRAADGRILVEGLYEEVQEPNEREMALLETYGQRNPEE
                     VSRIYGLELPLLQEERMAFLKRFFFEPALNIEGIQSGYQGQGVKTILPAEASAKLEVR
                     LVPGLEPHDVLEKIRKQLDKNGFDKVELYYTLGEMSYRSDMSAPAILNVIELAKKFYP
                     QGVSVLPTTAGTGPMHTVFDALEVPMVAFGLGNANSRDHGGDENVRIADYYTHIELVE
                     ELIRSYE"
     gene            30854..31915
                     /locus_tag="VQ540_000693"
     CDS             30854..31915
                     /locus_tag="VQ540_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HET2544529.1"
                     /translation="MSRDIIKLDQIDVTFHQKKRTITAVKDVTIHIQEGDIYGIVGYS
                     GAGKSTLVRVINLLQKPSAGKITIDDDVIFDGKVTLTAEQLRRKRQDIGMIFQHFNLM
                     SQKTAEENVAFALKHSGLSKEEKKAKVAKLLDLVGLADRAENYPSQLSGGQKQRVAIA
                     RALANDPKILISDESTSALDPKTTKQILALLQDLNQKLGLTVVLITHEMQIVKDIANR
                     VAVMQDGHLIEEGSVLEIFSNPKQPLTQDFISTATGIDEAMVKIEKQEIVEHLSENSL
                     LVQLKYAGASTDEPLLNELYKHYQVMANILYGNIEILDGTPVGELVVVLSGEKAALAG
                     AQEAIRQAGVQLKVLKGGQ"
     gene            31917..32609
                     /locus_tag="VQ540_000694"
     CDS             31917..32609
                     /locus_tag="VQ540_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2544530.1"
                     /translation="MESLIQTYLPNVYKMGWAGQAGWGTAIYLTLYMTVLSFIIGGFL
                     GLVAGLFLVLTAPGGVLENKVVFWILDKITSIFRAVPFIILLAILSPLSHLIVKTSIG
                     PNAALVPLSFAVFAFFARQVQVVLAELDGGVIEAAQASGATFWDIVGVYLSEGLPDLI
                     RVTTVTLISLVGETAMAGAVGAGGIGNVAIAYGFNRYNHDVTILATIIIILIIFAIQF
                     LGDFLTKKLSHK"
     gene            complement(32639..33208)
                     /locus_tag="VQ540_000695"
     CDS             complement(32639..33208)
                     /locus_tag="VQ540_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HET2544531.1"
                     /translation="MKKSILTTLLFAVLYFLCMGIGVLLGNLFDQTGNMFYAPAFTAL
                     VGGSVYMILVAKVPRFGAITTIGLVIALFFLGTKHGAGSFLPGIICGLLADGVAHLGK
                     YKDKTKNFLSFIIFAFSTTGPILLMWIAPKAYMATLLARGKSQEYIDRIMVAPNPGTV
                     LLFIASIVIGALVGALIGQALSKKFAQKI"
     gene            33343..33957
                     /locus_tag="VQ540_000696"
     CDS             33343..33957
                     /locus_tag="VQ540_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000532354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HET2544532.1"
                     /translation="MGRFLDFVFNRFFLGMIATAFFWLLTLAGGIILGLAPASATLMS
                     LYAEHGYSFREYSLKEAWSLYKQNFVSSNLIFYSFLGVGLVLTYGLYLLVQLPHQTIV
                     HLIATLLNVLVVALIFLAYTVSLKLQVYFALSYRNSLKLSLIGIFMSLAAVAKVLLGT
                     VLLVAIGYYMPALLFFVGIGMWHFFISDMLEPVYEIIHEKLATK"
     gene            33959..35605
                     /locus_tag="VQ540_000697"
     CDS             33959..35605
                     /locus_tag="VQ540_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET2544533.1"
                     /translation="MKQFWLHTLLRTYSSVMIIIIASFAILLSYADWDSREKEAQRVA
                     QRVTARTVSEIEYYHRESTQIAQALVENQARIEGIYKYFSLSMPDYFYWQLERKASPY
                     ISVSLYENVDDLYVRNDFVTGVAIAFQDYKEVYVSTKDKRSGEKIRAEDFKPAGNSFA
                     IPVSDPVSDQDLGVIYISLDPAVLYHAIDNTRGHTPMAVTVTSPFDTEIFHIGETVDR
                     ESENWLVGLTSHGYQVQVAVPKNFVLQGTVTSSALIVGLSLLFIVILYLTLRQTFANY
                     QKQVVDLVESIQVIAQGEEGRRIDISEKDQELLLIAETTNDMLDRLEKNIHDIYQLEL
                     SQKDANMRALQAQINPHFMYNTLEFLRMYAVMQSQDELADIIYEFSSLLRNNISDERE
                     TLLKQELEFCRKYSYLCMVRYPKSIAYGFKIDPELENMKIPKFTLQPLVENYFAHGVD
                     HRRTDNVISIKALKQDGFVEILVVDNGRGMSAEKLANIREKLSQKYFEHRASYSDQRQ
                     SIGIVNVHERFVLYFGDRYAITIESAEQAGVQYRITIQDE"
     gene            35617..36903
                     /locus_tag="VQ540_000698"
     CDS             35617..36903
                     /locus_tag="VQ540_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET2544534.1"
                     /translation="MYKVLLVDDEYMVTEGLKRLIPFDKWDMEVVATASHADEALEYV
                     QENPVDVIISDVNMPDKTGLDMIREMKEILPDAAYILLSGYQEFDYVKRAMNLSVVDY
                     LVKPVDKVELGNLLEKIAGQLGERGKKSQTLSQELDEAGFVSYLGDKENWWIGLSKEK
                     QGSFTIPYYVLGQDWQIFISDQPLDGLVVTPFEAPYQEHFERWKLNAEKTLFYGSVNL
                     QQSESLFAYYEPIYRVIIQGNLNQIVEELNLLEKVVLENTPRVPITKQLFIQFVMDVF
                     HLFEHLKADDLTDIVKTIHAIQSFDELVPYIKETLSSFFGQYRMNENVVSVLEVIGCD
                     YQKELSLKDISKALFINPVYLGQLIKRETDSTFAELLNKQRIKAAQQLLLSTSDSIED
                     ICYAVGYSNLGYFYKVFRKLCGKSPKAYRKQVETIL"
     gene            36964..37497
                     /locus_tag="VQ540_000699"
     CDS             36964..37497
                     /locus_tag="VQ540_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2544535.1"
                     /translation="MKKKPIYLWVLLILSALISVPSLFGIVSPLPSKEALRTAQKQVA
                     GVNAQQLEDQLNYTYRVAEASHSIFNVALIVLSTILVVVAIVFLVRKNLQYANYTYVG
                     YVLLAIIGSIYGYVGLQDAVQLVQDESMRLTVSIGSKAVSIFYIVINVLFLALVFYKM
                     WRQQKASAEEEETEELA"
     gene            37575..38045
                     /gene="nrdI"
                     /locus_tag="VQ540_000700"
     CDS             37575..38045
                     /gene="nrdI"
                     /locus_tag="VQ540_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HET2544536.1"
                     /translation="MKIISLVYISLSGNTESFVTRLKDYLLSQYKGIEVQKIHIKDLV
                     KEGKNFYEMDHPYVAFLPTYLEGGNGVDNGDVEILTTPVGDFIAYGNNASKCFGVVGS
                     GNRNFNNQYCLTAKQYSQRFGFPVLADFEMRGMLEDIKHVAAIIADLYELEKEN"
     gene            complement(38338..39600)
                     /locus_tag="VQ540_000701"
     CDS             complement(38338..39600)
                     /locus_tag="VQ540_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000075801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divalent metal cation transporter"
                     /protein_id="HET2544537.1"
                     /translation="MSQAISLNQSTWASKLKAMGPGILMATAAVGGSHIVSSTQAGGS
                     YGWSLLLLVILANVFKYPFFRFGAEYTADTGKTLVEGYAEKGKLYLWIFFILNVFSAM
                     VNTAGVAILCSAIIASAFPMIGLSITQWSLILVAIIWAMLLFGGYKLLDGMVKWIMSA
                     LTIATVLAVIIAAVKHPEYSSDFVEKTPWQMAALPFIVSLLGWMPAPIEISAINSLWS
                     AEKRKTVNFNTEDALFDFNTGYIGTAILAVFFVALGALIQYPTGQAVEAASAKYISQF
                     VGMYASVLGEWSRYLITFIAFLCIFGTVITVIDGYSRVNQESLRLLISQKEDNRKSLN
                     IWMTITAIIGIVIIKFFSGQVSTMLRFAMIGSFLTTPFFALLNYALVTRENKNLPSWL
                     KHLAIAGLIFLFGFAIFFIYALAIGKAG"
BASE COUNT        12063 a         6878 c         8571 g        12206 t
ORIGIN      
        1 caacaggttg ggtgaaagat ggagatacct ggtactatct tgaagcatca ggtgctatga
       61 aagcaagcca atggttcaaa gtatcagata aatggtacta tgtcaatggt ttaggtgccc
      121 ttgcagtcaa cacaactgta gatggctata aagtcaatgc caatggtgaa tgggtttaag
      181 ccgattaaat taaatcatgt taagaacatt tgacatttta attttgaaac aaagataagg
      241 ttcgattgaa tagatttatg ttcgtattct ttaggtacct atcttatgat ttcaggaaat
      301 gtcattaaaa aaacgactcc ttttctctaa cttgaaaaat agattagaga aaatgggttg
      361 ttttatttat tatagttatt tgaatgaaga taagaagaag gtatactcac atcattcaca
      421 taatctgtat gttgactata agtttaaaaa aacaattttt aagctcttcc ttgtcttctc
      481 caaccaagcg tgttataatg aatactgctc aagcgacctt caatcgtgaa gcacacacga
      541 ccttcaatcg tgaataaacg aatagatggg agacttacca tgagtgataa ctctaaaaca
      601 cgtgttgtcg tggggatgag tggtggtgtt gattcgtcgg tgacggctct tttgctcaag
      661 gagcagggct acgatgtgat cggtatcttc atgaagaact gggatgacac agatgaaaac
      721 ggcgtctgta cggcgaccga agattacaag gatgtggttg cggtggcaga ccagattggc
      781 attccctact actctgtcaa ttttgaaaaa gagtactggg accgcgtttt tgagtatttc
      841 ctagcggaat accgtgcagg gcgcacgcca aatccggacg ttatgtgcaa caaggaaatc
      901 aagttcaagg cctttttgga ctatgccatg accttggggg cagactatgt agcgactggg
      961 cattatgctc gagtggcgcg tgatgaggac ggcactgttc acatgcttcg tggcgtggac
     1021 aatggcaagg accagaccta tttcctcagc caactttcgc aagaacaact ccaaaaaacc
     1081 atgttccctc tgggacattt ggaaaagcct gaagtacgca gactagcaga agaagcaggc
     1141 ctttcgactg ctaagaagaa agactcgaca gggatttgct ttatcggaga aaagaacttt
     1201 aaaaactttc tcagcaacta cctgccagct cagcctggtc gcatgatgac tgtggatggt
     1261 cgcgatatgg gcgagcatgc aggtcttatg tactatacaa tcggtcagcg tggcggactc
     1321 ggtatcggtg ggcaacacgg cggtgacaat gccccttggt tcgttgtcgg aaaagatcta
     1381 agcaagaata ttctctatgt aggacaagga ttctaccatg attcgctcat gtcaactagc
     1441 ctagaagcca gtcaagtcca ctttactcgt gaaatgccag aagagtttac gctagaatgt
     1501 acggctaaat tccgttaccg tcagcctgac tctaaggtga ccgtccatgt caaaggagac
     1561 aaggcagaag ttatctttgc ggaaccacaa cgcgcgatta caccaggaca ggcagttgtc
     1621 ttttacgatg gcgaagagtg tctaggtggc ggtttgattg acaatgctta ccgcgatgga
     1681 caagtttgtc agtacattta gattgacaaa ttttctcaat ttgctacaat aataacagca
     1741 atagaaatga tggtcaaagc tcatggatgt tgcaggcttt tttgtcctgc acttctttgt
     1801 agttttgact gtttttgtgt cgtttaaggg aaaggacaag aatgactcaa caagactttc
     1861 ggacaaaagt agacaatacg gtttttggtg ttcgggctac agccttgatt gtccaaaatc
     1921 acaagcttct agttaccaaa gacaagggca agtattacac tattggaggt gcgattcaag
     1981 tcaatgaaag cacggaagac gcggtagtcc gtgaagtgaa ggaagaactg gatgtcaaag
     2041 ctcaagctgg gcagctagct tttgtggttg aaaatcgttt tgaagtggac ggcgtttcct
     2101 atcacaatat cgagtttcat tatctggtgg atttgcttga agatgccccg ttgaccatgc
     2161 aggaagatga gaaaaggcag ccctgtgagt ggattgactt ggataagctc cagaatatcc
     2221 agctagttcc agccttttta aaaacagccc taccagattg ggaaggccaa ctaagacaca
     2281 ttcatcttga ggaataggag agaaacatga cttatcattt tactgaagaa tacgatatta
     2341 ttgtaattgg tgcgggacac gctggggttg aggcttcctt ggccgctagc cgtatgggct
     2401 gtaaggtcct gcttgcgacc atcaatattg aaatgctggc tttcatgcct tgtaatccct
     2461 ctatcggtgg ttctgctaag gggattgtcg tacgtgaagt cgatgccctc ggtggcgaga
     2521 tggccaagac cattgacaag acttacatcc agatgaagat gctcaacaca gggaagggac
     2581 cagccgttcg tgcccttcgt gcgcaggctg ataaggaact ttactctaag gaaatgcgca
     2641 agacagttga aaatcaagaa aatctgaccc ttcgtcaaac catgattgat gagattttgg
     2701 tggaagatgg caaggttgtc ggtgtgcgta cagccaccca tcaagaatat gctgctaagg
     2761 ctgttattgt gacgacaggg actgctctcc gtggggaaat tatcatcgga gacctcaagt
     2821 actcatcagg tcctaaccac agcttggctt ctattaacct agctgacaat ctcaaggaac
     2881 tgggtctcga aatcggtcgt ttcaagacag gaacccctcc acgtgtcaag gcttcttcta
     2941 tcaattacga tgtgacggaa attcagccag gagacgaagt gcctaatcat ttctcataca
     3001 cttcacgtga tgaggattat gtcaaagatc aagtgccatg ctggttgacc tataccaatg
     3061 gtaccagtca tgagattatc caaaacaacc tccaccgtgc gcctatgttt acaggtgtgg
     3121 tcaagggagt ggggcctcgt tactgtccgt cgattgaaga caagattgtg cgctttgcgg
     3181 acaaggaacg tcaccaactc ttccttgagc cagaagggcg caatactgag gaagtctatg
     3241 ttcaaggact ttcaaccagt ctgcctgagg atgtccagcg tgacttggtt cattccatca
     3301 aaggtttgga aaatgcagag atgatgcgga caggttatgc tattgagtat gatatggtct
     3361 tgcctcatca gttgcgtgcg actttggaaa ccaagaaaat ctcaggtctc ttcactgctg
     3421 gtcagacaaa tggaacatca ggttatgaag aagctgctgg ccaagggatt atcgcgggta
     3481 tcaatgcggc tctgaaaatc caaggtaaac ctgagttgat tctaaaacga agtgacggtt
     3541 atatcggggt gatgatcgac gacttggtga ccaagggaac cattgaacct taccgtctct
     3601 tgaccagtcg tgctgaatac cgtctcattc ttcgtcatga caatgctgat atgcgcttga
     3661 ctgagatggg acgcgagatt ggccttgtgg atgatgaacg ctgggctcgt tttgaaatca
     3721 agaaaaatca atttgataat gagatgaaac gcctagacag tatcaaactc aagccagtca
     3781 aggaaaccaa tgctaaggtt gaggaaatgg gcttcaagcc gttgacagat gcggtgacag
     3841 ccaaggaatt ccttcgccgt ccagaagttt cttaccaaga tgtggtggcc ttcatcggac
     3901 cagctgcaga agacttggat gacaagatta tcgaattgat tgaaacagaa atcaagtacg
     3961 aaggctatat ttccaaagcc atggatcagg ttgctaagat gaaacgtatg gaagaaaaac
     4021 gcattccagc caatatcgac tgggatgaca tcgattctat tgcgacggaa gctcgtcaga
     4081 agttcaaact catcaatcca gaaaccatcg gccaagccag ccgtatttcg ggagtaaacc
     4141 cagcagatat ttctattttg atggtgtatc tggaaggtaa aaatcgtagt atttctaaaa
     4201 ctcttcaaaa atcaaaatga tacgtcgtcg gcttcttacg aatgagttca aagcttggct
     4261 ttgattcatc tccaacctcc catagttccc cgaactatgg gagctaactc aagttatgca
     4321 ttttcctagc cttctggtct gattttcatt gagttttaat ctcaaaagaa agcatagaga
     4381 aaaacagctc cgaagacggg gctgttttgt tgacttgtac tcaatgaaaa tcaaagagca
     4441 aactaggaag ctagccgtag gttgctcaaa gcactgcttt gaggttgtag atagaactga
     4501 cgaagtcagc tcaaaacaca gttttgaggt tgtagataga actgacgaag tcagctcaaa
     4561 acacagtttt gaggttgtgg atagaactga cgaagtcagt aacatatata cggcaaggcg
     4621 aagctgacgt ggtttgaaga gtattattct tcatctggtg tgaggatcat cgggatgatg
     4681 atcggttcac gttcggtatt ttcatagagg aaggggcgaa tagcgttgac aatggcacca
     4741 ttgacagatt gcacgctagc atccttattt ttcagtgcga tacgaatggc attgaagagg
     4801 atacgctggc tttggcgaat caagtctcca gactctctca tgtagacaaa gcctcggctg
     4861 aggatatctg ggccagacag aatcatctgc gatttgaagt caacagttgc gactgccaga
     4921 acgacaccgt cttcagatag atcgcgacga tctttgagga cagctgcgcc aatttcaccg
     4981 atacgatttc catcgacata gatatcttgg gcgttgaaat gacctgcgat acgagctgag
     5041 tcagcagtaa gggcaagcac atcgccattg ctcatgataa agatattgtc tttctcaaca
     5101 ccagtatcca ctgctagtcc agcgtggact ttttgcatgc ggtattcacc gtggacaggc
     5161 atgaagtatt ttggcttaat caagcggagc atgagttttt gctcttgctg accaccgtgt
     5221 ccagatgtat ggatattgtt cactttaccg tggataactt cgacaccagc ttcagaaatg
     5281 atgttaatca gcttgttgac gctagtagtg tttccaggga tgggactaga agagaagata
     5341 acggtatcac ctggttgtaa ttgtacttga cggtgggttc cgttggcgat acgagagagg
     5401 gctgccatag gctcaccctg actacctgta cagaggataa gaacttctcc tgcaggataa
     5461 tctttgattt catttggctc gataaaggtt cccttaggag ctttgatgta gccaagatcg
     5521 attccgttga caatggcctt ttccatagaa cgaccaaaga ccgcaatctt gcgtccagtc
     5581 ttaacagcag cttctgttgc ctgctggaga cggaagatat ttgaggcaaa ggatgcaaag
     5641 atgatacgtc cttcaatacc ttggataatc ttcataatgg actgaccaac gactttttca
     5701 gagttggtaa aggttggtac ttccgcattt gtcgagtcag acaggagaca gagcacgcct
     5761 tcttcaccaa gcgcagccat acgatgcaag tccgcaggtt ctccaactgg agtaaagtcg
     5821 aacttaaagt cacccgtaca gacgattttc ccttgaggag tatgaatgac aatccccaaa
     5881 ggctctggaa tagagtgagt cgttctaaag aaagttgcct tgagattttt aaaggtcaac
     5941 tcggtgttgt ggttgatttc gtaaagtttg gcgttgcgca agaggccgtg ttcttcgagt
     6001 ttcccacgga tcaaagccaa ggcaagcggt ccagcgtaga tagggacatt tgcttgcttg
     6061 agtaggaacg gaatcccacc aatgtggtcc tcgtgtccgt gtgtgattaa aacagccttg
     6121 acgcggtcga tattgtctac gatgtaagag tagtcaggaa tgacatagtc gataccaagc
     6181 aagtcatctt ctgggaattt aatcccagca tcgacgatga taatctcgtc ttggtattca
     6241 attccgtaag tgtttttccc gatttctcct agaccaccga tggcaaaaac accgacttct
     6301 tcaggtttaa gagtgtaggc catattagaa ctccgtaatt tcgaaggcgc cagtttcttt
     6361 ttcgtaatcg agcaatttgt cagacaagag ttcgatatat tcgatattgt actctgggcg
     6421 attttcttcg acaagttggc gagcagtgat acggccctca agttctgagc tggcatcgat
     6481 gtctaggtaa agcgcgcgtg ttgtttcacg gcgtgggcta cgttcttttg tttcttgata
     6541 aaaaactttg taaatcatat agttcctttc tatttacagg tcagcttatt ccaaactttt
     6601 agcagatatt tgcttgattt cattccattt tgtgtctaga ttgaccttga ttcgttacaa
     6661 ttatttcaat tataccacaa aatgaaaaat tagtaaaaga cggaaacgag aaagttaggg
     6721 gacgatttct tcggtaagcg tttgcaaaaa caaagaaaat gtgttatgtt gataacggaa
     6781 gtgaagttta ttacttgtca taattccata tagattttaa gtcaaggagg ttgccctatg
     6841 tataacttat ttgcttttgc tatcggagtt cgtttgctag cttttatcgt ttttgttttg
     6901 cgtttatgga ggaaatcttc tatttgccaa actggaacga tgacaaacca agttcttgag
     6961 gaaaattacc tttgtgactc tctactcgct ttttctcctc ctcgtgacct atgtcgtttg
     7021 gtttgtattt tactttggat taaatgctta gatgccctgc ttatgctggg gttttttgtt
     7081 tggggatgta gagatagtag atttacgaca cgaaaattcc accccatcta tcaagatgag
     7141 gtggtctttg catttttcta aaatgatatg acaatggaat tttcaaagct tattattttt
     7201 atgggagtca ttgttctgct caaaaataga gttgaagcat aaaaataaaa caatacaaac
     7261 agataaatcg aatggtaaag ggatggtagt aatgttcaaa tcattgagaa tgctgagcaa
     7321 actgtaagag atgaagacaa taaaatttat ccttctaaaa atgtgtttct tatctagcat
     7381 gacttaccaa actttttacg aaggtctttt ccaatggtat aacctgccat aaataaagcg
     7441 ataccaacac ctacaccaaa gccacccttg atttcttgca attccttatt agaaatttca
     7501 cgacagttgt tcaaatcttt catcatatta atctcctcct aaaaaataac cagctgccaa
     7561 accagaacct ataagtgctg ttccacctgc aatagctttc caagatactg ctactccaaa
     7621 gataaccaag ggagcgagac cgccatcaat atctgataat tcattttcag ataaggataa
     7681 aaattgattg tcaagaatgt caaaatttgt cattgaactt tcctcctttt ttcttgttca
     7741 cttttatatt cggaaaagaa aaggaaaagt gagcattttt ttaaattatt tttagttaag
     7801 tgagggcact cttgtctggg ggcaaagaaa attcccatgt gccatctttt gtagtataat
     7861 agtaagcaga caaaaagata ggaatgtgtt atgaaagtat tagcttttga tacgtccagc
     7921 aaggctcttt ctctcgctat tttagaggat aagcaggttc ttgccgagac gacgattaat
     7981 atcaagaaaa atcacagtat taccctcatg ccagccattg attttttgat ggagagtttg
     8041 gactggacgc ccaaggattt ggaccgaatc gtggtggcgg aagggccagg tagctacaca
     8101 ggcttgcgaa tcgcggtagc cactgccaag accttgactc atactctgaa cattgagtta
     8161 gttggtatgt ctagcctctt ggctctggtg ccatatcaac aagaaggctt gttcgttcct
     8221 ttgatggatg cgcgtcgcaa caatgtttat gcaggatttt atgaaaatgc taaacctgtc
     8281 atgccagaag cgcacctatc ttttgaagag gtgctagaaa aagtcaaggg tgctagtcag
     8341 gtaacctttg tcggagaagt tggccccttt gtggagcaga ttcaagaaca cttgccaagg
     8401 actaattata aagaaacctt gcctaatgca gccaatcttg ctcttttagc ttgggacaag
     8461 gaagcagact ccttgcatga ttttgtgcca aattacctca aacgagtcga ggctgaggaa
     8521 aactggctca agaaccatac cgagtctggt gagtcctaca ttaaacgcct atgatagaaa
     8581 tcaagcgaat tcaacaacag cctgacctag ctcaagccat ctacgctgtt atggcagctg
     8641 tttacctagt cagtccttgg actctggagc aaatccaagc agatctgtcc caagaccaga
     8701 cttggtatgc attggcttat gatggggcag aagtgattgg atttctagct gtgcaggaga
     8761 atctttttga agcagaagtc ctgcaaatcg ctgtcaaagg agcttatcag ggtcagggaa
     8821 ttgcgtcagc cttgtttgct caattgccga cagataagga gattttcctc gaagtcagaa
     8881 agtcaaatca acgagcgcaa gcattttaca agaaagaaaa aatggcggtc atcgctgagc
     8941 gaaaggccta ctaccatgac ccagtcgagg acgccattat catgaagaga gaaatagatg
     9001 aaggatagat atattttagc atttgagaca tcctgtgatg agaccagtgt cgccgtcttg
     9061 aaaaacgacg atgagctctt gtccaatgtc attgctagtc aaattgagag tcacaaacgt
     9121 tttggtggcg tagtgcccga agtagccagt cgtcaccatg tcgaggtcat tacagcctgt
     9181 atcgaggagg cattggcaga agcagggatt accgaagagg acgtgacagc tgttgcggtt
     9241 acctacggac caggcttggt cggagccttg ctagttggtt tgtcagctgc caaggccttt
     9301 gcttgggctc acggacttcc actgattcct gttaatcaca tggctgggca cctcatggca
     9361 gctcagagtg tggagccttt ggagtttccc ttgctagccc tcttggtcag cggcggacac
     9421 acagagttgg tttatgtttc ggaggcagga gattataaga ttgttgggga aacccgtgat
     9481 gatgcggttg gtgaggctta tgataaggtc ggccgtgtca tgggcttgac ctatcctgca
     9541 ggtcgtgaga ttgacgagct ggctcatcag gggcaggata tttatgattt cccccgtgcc
     9601 atgattaagg aagataatct ggagttctcc ttctcaggtt tgaaatctgc ctttatcaat
     9661 ctttatcaca atgccgagca aaagggagaa agcctgtcta cagaagattt gtgtgcttcc
     9721 ttccaagcag cagttatgga cattctcatg gcaaaaacca agaaggcttt ggagaaatat
     9781 cctgttaaaa ccctggttgt ggcaggtggt gtggcagcca ataaaggtct cagagaacgc
     9841 ctagcagccg aaatcacaga tgtcaaggtt atcatccccc ctctgcgact ctgcggagac
     9901 aatgcaggta tgattgccta tgccagcgtc agcgagtgga acaaagaaaa cttcgcaggc
     9961 tgggacctca atgccaaacc aagtcttgcc tttgatacca tggaataaag agtggctctt
    10021 tgtcaagtgt agtgggtagt cgaaaagctg caatctggag agtacgaaat tcgtactctc
    10081 ttttttgatg ttcaaagtca tcaaaatccg ttttttaaaa ttgttaaagt tccggaaacc
    10141 aaaggctttg cgcttgataa tcttaatcaa attattggtc gcttcaagtt tagcgttgga
    10201 ataaggcagc ttaagtgcgt tgataatctt atctctatcc cttaaaaaag tccaaaagac
    10261 cgtttgaaaa agcggatgaa ccgttggcag ttcttgctca atcaatccaa agaaatggtc
    10321 ggcattcttc tcttgaaaat gaaagagcag gagttgatag agttcgtagt gaacctgtaa
    10381 tccctcagag taagaaagca gcttatctcg tacttcccga tgggttaagt gcattcgaaa
    10441 cgtgggctga tagaatcgtt tctgacagag cttgaagcta tactggtgta gtaaatcagt
    10501 ccagtggact gatttagccc gagcctagaa acgaaaaagc gagggttcca aaagcgcttg
    10561 agcgcccgat actccaagga ttttcggtca aattggttca tgatttggat tcgtactcgg
    10621 ttcatagctc ggctcagatg ttggacaatg tggaagcggt caagaacaat cttcgccttt
    10681 ggaaagagtt gcttagcgag ccgataataa gggctgtaca tgtccatggt gatgacctcg
    10741 accagctccc gaacctctct ctgatagcgt tggaaatggt ttcgaatcac cgcatgagtt
    10801 cgcccgtcta aaattgcgag gatggatttg gactcaaaat cttgggcaat gaagctcatt
    10861 ttgctctttt tgaagctata ctcatcccaa ctcataactt ttggcaactt ggtccaatcg
    10921 gtttcaaact taaattccct cagttttcgg atgacggtgg aagttgagac cgccaatctg
    10981 tgggcaatct cagtcataga ctgcttttca aggaggagct gagcgatttt ttgtctcacc
    11041 atgttggaaa tctggcaatt tttcttgaca atggatgttt gagaaacgac caccttaagg
    11101 caattcttgc actgaaagcg gcgctttttg agatgcagta ccgtgggtaa accctgacag
    11161 tcgagaagcg gaattttaga ggctttctgg aagtcgtatt tgatcatctt cccttgacaa
    11221 tgaggacaag gaggagcggg ggaatccaac tttgcctgaa cgactagatg ggtttggtat
    11281 ttcagaacag acaagatttt gatatttttg tcttccaatc cgagcaaatc tgtggtattc
    11341 ttaagttgtt ccatatggac cctttctaat gagttggtta gacgcttttc attataggtc
    11401 atatggggct ttttttctac aagaaacgac cctataattc ctggggtggg attacccact
    11461 acagaaatta tagagccaaa gcattccaaa gtcttgtctg actctggaat gttttctgtt
    11521 cacagttgtt ttgtaactgc ctaataagta accgcgctat aacgaggtat ctaccgagat
    11581 tgtcaattct ccagtatact gttataaaaa acaaaactgg aggatttttt tatgtcctcc
    11641 catcgtccca tcgactgttc cgtagctgcc caataacgga gtatagtcgg ctgaaacaag
    11701 aataggacaa aagtgcctca agaaaagcat cgtaatttga caatattatt ctgagatgtt
    11761 tttgatgtaa gcccatattt tctcaatggg attatactcg ggtgaatagg taggaagtgg
    11821 taacagtcta tgccctgctc cttacacatg ttcattctgt gaaaccttgc attgtccata
    11881 atgataaggg atggtgtatc taaagtaggt agtaagaatt tttggaagca agcttcgaaa
    11941 aagtcactcg tcatcgtatc tttataggtc atcggagcca tagtatattg aaacaaaaaa
    12001 gggcattagt acttctataa cagtatcgca atctctggtg tgcgttgtct cgatcttaat
    12061 tcaaataatt atatcttctt ccagagagac taactgcctg ctcaaggctc gatcatattt
    12121 gagataaaaa taggtctcaa cccctgtctc ataaatataa ataggagtca ggtagcttaa
    12181 gtgattcaat tctttaagga accgatttac tttttctggg tcttgttcgc agtaggtacg
    12241 gctcttttta gactatatcc catagccttt agagcgtaat gaatagttgt tggaggacag
    12301 ttgaattcag cagctatttc agtcaaataa gcatcgggat gagtttcaat atagatcttt
    12361 aatttatctc tatcaacttt ttcaattaat agtggaagtt ttcttaaagt tagtgtgttg
    12421 aaacgttttt atacagtgct aaaatttgaa gtgtagtgca gatgtatttg taatagtatt
    12481 atagcaattc tttggagaag gtcgagacaa gagaaaatag gtatctttga gatataagta
    12541 tgatttacta taaaattatt gagttattca taaaaatttc tctatcaaat atcataatgc
    12601 gtcgtttaag gagatggtta caatgcaata tagttgtgga aaaataaata ttaatatccc
    12661 tgatggatat ggagacatta aggatatagt gttttcggct catattatag ttaggtataa
    12721 taatggacat tgtggaggta tagatccgca tataattgga ctttgtaaaa agcagatcag
    12781 aaggatgtct ccatatccta ttttgataat cgtatctaga gattcaaagg ttattgatga
    12841 ttataaaaat ttagatattg cctatgttga ttgtactcaa tgttcaaata attttgaaac
    12901 tgccttacac gttaaaaata ttttaaaatt attaaaaatc caacttatac actgtcatgg
    12961 ctactcaact aattattttt tatatatgtt aaaaaaactt gacaagaatg gatttggaaa
    13021 ggttaagaca gtgataacat gccatggatg ggttgaatat aacttaaaaa agaaattctt
    13081 gacttatttt gatttttgga catattctat gggagatgct tttatttgtg tatctgaaac
    13141 tatgaaaaaa agattggaga gtataataaa aaaataagaa gatagttgca ataaataacg
    13201 gaattaatgt atcaaatagc gatttagatg tagtaggtgt tcaagacttt aaaaaagaat
    13261 tttgtattcc aaataacaaa aaaatcattt gttatgttgg aaggttggat ccagaaaaaa
    13321 ggccggatag attccttgaa tttgcagaaa aattattttt agtcagagaa gatgtgattt
    13381 ttattatggc tggaaatggt agtatgtggg ctactttgaa agaaaaaatt tgccatttga
    13441 aatgtagaga taatttcagg ttacttggtg aaatctatcc agctactata gtttaccaaa
    13501 tatcggattt attgtatatt ccttctgata cagaaggaat acctatgtgt gttttagagt
    13561 caatgtcaca agaaactccg gttttagcta gtaatgttgg cgggttaagt gaaattattg
    13621 aacatagggt tgatggattt ttatttgaga aggaagatgt tgagggagtg tgtgcttgtg
    13681 ctaatttttt actcaatgat tctgagtatt tgaaatatat aggtgagaat agtaaatcaa
    13741 aaataagaaa acatttttct gtgcaaaaaa tgtttgtaga aaccatgaga gtatatgatg
    13801 aattattaga gaagagtagt catggatagg aatatagatc aagaattagt aagtattata
    13861 ataccaacac ataataggta tgaatctctg attagagctg tgaaaagttg tttacatcaa
    13921 agttataaaa atatcgaagt tataattatt gatgataatt atagtaatgt aaatttaaga
    13981 aataaaatta tccatcaatt tggctatacc agtcatagaa ttaagttaat tttaagtaat
    14041 gaagatttag gtgcaactaa tgccagaaac ataggtatca aaaattctag aggtaagtat
    14101 atatcatttt tagacgatga tgatgaatat atgccagatc gaattttaaa gttgatggct
    14161 tgttttaaaa agagtagaat gaagaattta gctttagttt atagttatgg aataataatt
    14221 tatccaatag gaaatatttt aatttattga gtttcaacga gagaatattg gttacaaaga
    14281 aatattattc tttaaacata aagcggttac tattaatagg agacaaatgc aaggctttaa
    14341 aagtaatcaa gaaggcaaga gaagaaaaaa tttttaacga atttcttttt cgaaatatat
    14401 gttattatat cattttggtt ttttctattg tatatatgac aactatgttc aattaaaatt
    14461 tagaaagtga gaaactattg tgtatactat tataaaatca aatataaaaa aatttagttt
    14521 attaacgata tttattgttg ctggtcaatt attgctaatt tatgcagcaa ctattaatgc
    14581 tctggtgttg aatgaattaa ttgcgatgaa tttagagcgg tttttgaaat tgtcaatcta
    14641 ccaaatgatt gtctggtgtg ggataatatt ccttgactgg gtagtgaaaa attatcaggt
    14701 tgaagtgatc caagagttta atctagagat tcgaaataga gttgccacag acatctctaa
    14761 ctctacctat caagaatttc atagtaaatc atcaggaaca tatctttcgt ggctaaataa
    14821 tgatgttcag actttaaatg atcaggcttt taaacaactt tttttagtaa taaaaggaat
    14881 ttctggtact atatttgcag ttgtgactct taatcactat cattggtcat tgactgtagc
    14941 caccttgttt tcattaatga ttatgctact tgtaccaaaa atctttgcat cgaaaatgcg
    15001 agaagttagt ctaaatttaa ctaaccaaaa tgaagctttt ttaaaatcta gtgagactat
    15061 attgaatgga tttgatgtgt tagcgtcctt gaatctttta tatgtattgc ctaagaaaat
    15121 taaagaagca ggaattttat taaagatggt tatacaaaga aagacaactg tagaaacgtt
    15181 agcaggcgct attagcttct ttctcaatat tttttttcag atatctctcg tttttttaac
    15241 aggctatctt gcaataaaag gaatagtgaa aattggtact attgaagcaa taggagcact
    15301 aacaggtgtt atttttacag cgctaggtga attaggaggt caattatcct ctattattgg
    15361 tacgaagcct atttttttaa aattgtattc aattaatcca attgagtcaa ataaaatgaa
    15421 tgatatcgaa ccaaatgagg tgaatagaga ttttccgtta tatgaagcaa aaaatatttg
    15481 ctataagtat ggagataaag aaatattaaa aaacttaaat ttttgttttc aacgtaatga
    15541 aaagtattta attttaggtg aaagtggaag cgggaaatct acattattaa aattattgag
    15601 tggctttttg agagattata gtggagaatt gcgattctgc ggggatgata taaaaaaaac
    15661 ctcctattta aatatggttt cgaatgttct atatgtagat caaaaagctt atttgtttga
    15721 aggtacgatt agagataata ttttattgga agaaaattat actgatgaag aaatactaca
    15781 gtctttagag caagttggtt tgagtgtaaa agattttcct aataacattt tagattatta
    15841 tgttggtgat gatgggagat tactgtcagg agggcagaaa caaaaaatta ctttagctag
    15901 agggctaatt agaaataaga aaatagtatt aattgacgag ggaacttctg ctatcgatag
    15961 gagaacttcg ttagcgattg aacgtaagat attagataga gaggatttga ctgtcattat
    16021 tgttacccat gctccgcatc cggaacttaa acaatatttt actaagatat atcaatttcc
    16081 aaaggatttt atttaagaat ataggggagg gaaacatgag attctattgt gaagcttatg
    16141 aggtaattac tgaagagaaa aaagtatact ttaatgatat tgagttagaa gttaagtatt
    16201 cctctgtcga agaattgttt ataatatgtg agaaattatt agataagaaa aaagtatcat
    16261 ttttttatgt atatgagaaa cccttaaggt atctgttatt tgactatata tttctactag
    16321 ttctagctaa aaaaaatatc ccaatcttag atggagtttc caataagcaa gttgatccaa
    16381 cgttgctgca tcacttttct ttggaaattg aaaagaattt tatcgatttt tgctataaaa
    16441 atatggatct catcctaaaa actcaaagta tatctttgtg tcatagagaa gagcttatta
    16501 ttgtagatgt ttcagatgac tctaaatttg gtgtttttta caagcgtttt agaacactgg
    16561 ttgataaaaa taacggaaaa tatgtttgtg tttataattt cagtcgtgtt tcagatatac
    16621 tgcaaaactg gaaaaattat tgcaatcgaa aattttcggt tacgtttact gaaagccaat
    16681 ttgaattatt taagctttta tataatcaaa aaaattttaa aacaatttcg ttgctatttg
    16741 gaaaaaaatt gttgctggag gaattatcta ttatagcgat cttactaata tagaatactt
    16801 ttgtattttt tggtgggata gtatgtttgg gaaagattct attggaaaat acgtatatgt
    16861 agaagagatt agtagatgtc attttttaga tagaaattat tctttttgtt atggtttaca
    16921 agattataaa agtaaactta ttaaatattt tttagaatag ttaatctatt cgagagagat
    16981 aaagaaatat ggaaaatact ttattgaata tcacaggaag cttcgatatg gaaactagga
    17041 atctaattag ttattcttta actgatatct ttgaaacaga taaaataaga attgaacttc
    17101 ttggagaaat ttattataaa aatataaagt tggaattgca tgaattcgct ggattgtata
    17161 agatttatgg aattagctta ataaagaata ttaccggaat gtttttaatt ataatttttg
    17221 atacgaagac aaaagaatta aaaatttttc aagatataac gacttcatac tttaatttat
    17281 actatactgt ttatggaggt gtgttctata tatagtacat ctttaaagaa agtgatgaag
    17341 ttatctcatg ttcccgttac cttaaataac aaaaaaatac aagaatttat gagaaatgga
    17401 tttattttag attcaaatac tttagtaacc gaaattaata aattagaata tttctcttac
    17461 atttctgtaa ataatactct tcgtatatgt ggtattgatt ataatgattc aaacaatttt
    17521 actaaagaac aagtattaaa gaattgggac tctatgctac gtgaatctat attaagagtg
    17581 tatagtgaag caggagaggc taatattaca ctatcatctg gttttgattc aaattatata
    17641 ttatatacat tagcgaatta tacgaattct tcaattaatg cattttgcat aggaggagaa
    17701 aaaggaatta atgagattcc tgaagtaact aaaattgcaa aattttatgg tataaattta
    17761 ttagttgata ctgtaatgag cccaagattt agaatatttt cccgatatag tatggagatt
    17821 ggaaggaagt ctctttgaat gtggtgtcat actgcagtac tatttaggca ggttgttgtt
    17881 ccaaaaaggg aacacaagta ttctttgtgg cgagtcagcg gatgaaataa tgacttttaa
    17941 gtatcattct gtgaactaca atcaattttg taatgataaa cagaagtcag tatattttag
    18001 ttattccgac tatccatttt atgttacaaa ttcaattgtt ttaaagaaaa atagcctact
    18061 tttgcatagt tttggcattc atcctagata tccatataaa atgtctgaga ttgttgaaat
    18121 gtctaaaaaa atatcagatc taaacgataa aaaagaattt cacaaaaaga actgtgagtt
    18181 gaggtttcaa gatagtgttc ttgataacat aaatagtgtc ccgggtacaa ctcatttatt
    18241 tagttgttta aatattcaaa cattagtaaa aattatttta tatatttttc gatacaacag
    18301 ttgtatgaaa atatttaatt ttagagataa agagcttatc ttttttaata agattgtaaa
    18361 tgggctgata caaaatattg aggagaattt agaggatgat attgaaagga tattgaaata
    18421 tttatatata tgtttattta acgaaatatt cattattaag aataaggtga atttttttga
    18481 tgatgtggaa tttaatcaga cacttagtga gtttttagat aaattgtaga gggaatggtt
    18541 atgagtgaca atactaagta tatcttttta tctccacatt tagatgacgc aattttttcc
    18601 tgtggtgatt atatttcaaa attaacttca gaaggagaaa ttgtacttgt tattactata
    18661 ttttctggtt accctttgag ccaacagcta cagccctctg ctaagcaatt tcataagttg
    18721 tgtaaccttg ggaaatatcc gattgaagaa aggaagaaag aagacaggtt agcttgtgaa
    18781 cgtctacaat gtgattttag acacttatcg tactatgaat gtctctatag gaaagataga
    18841 aatggcaatt ttctataccg tcatatctat agtaaattaa aaaatgagga cacattaaag
    18901 aatgatatca taaaagagct gttaatgcat ttagacgaca aatgtgtcgt atattgtccg
    18961 ctttcacttg gtgaccatgt tgatcatgtt tttgtgaata gtattggaag ggcgcttgaa
    19021 tttatgcgtt ataaagtaat atattatgag gacttcccat atgtaagtga tagtagtatg
    19081 gttagttata tgggaaaaac taaagaatta aaaatgtatc aagaggaact tgatgaaaaa
    19141 cattatattg atagaatatc atcaatattg tgctataaat ctcagatttt gataatctgg
    19201 aaatcagttg aaaaactttt aaacaatatt aaagagttgt atttaaggaa tggggcagct
    19261 tattctatta gattttggat taagaaataa ggaagtagtt ttatgaatat agcagtaatt
    19321 ggtttggggc atgttgggct ggcctacgcg ttactatttg catctaaata taaagttgtt
    19381 gcatatgata tagattctgt aaaaataaat aatttaaaaa agggcactct tccatctaaa
    19441 aatgaagagc ttatgaagtt tttttgcgag aataacttaa atattacttt ttttgataca
    19501 ttttctgaaa ttaaaaataa tattgattat tatattattg cgcttccgac agattatgat
    19561 gagaaaattg gtagttttaa tacatatgaa atcgaacaaa cggtatcgaa gattctgagg
    19621 gtaaaaccta atggaaagat tattttaaag tcaacagttc cgatcggctt ttcaaacaaa
    19681 ttaaaaaggc tgtttgatac aaaaaatatc atttttgtcc ctgaattttt gagagaaggt
    19741 tgttctatat atgataattt atatccaagt cgcatagttg ttggagatga gacagttgaa
    19801 ggaagaaaaa ttgcagagtt gttcctttcg attagtactc atagtactgc caatattaaa
    19861 aatgttatgt tagtttctcc tactgaagca gaagcaatta agcttttttc taacacattc
    19921 ttagctctcc gtgttgcttt ttttaatgaa ctagattctt ttgctgagag gagaagttta
    19981 aatgctgaag ttgtaataaa aggtgtttgt ttagatccaa gaattggaaa tttttataat
    20041 aatccttctt ttggatttgg aggatattgt cttcccaaag atactagaca attaaaaaaa
    20101 gaatttatag aaataaatgc cccagtgata gaagcgattg atatttcaaa cacaaataga
    20161 aaacagttca tagttaaaca aatattggaa cgaaagccaa agatagtagg aatatataaa
    20221 ttggggatga aatataattc agataattac aaagagtcag ctattttaag tataattaat
    20281 gaactattga ttgtcggtat aaaaatttta gtatatgaac caaatttaaa cgttagtata
    20341 gataacgtaa tttttgaaaa gaattttgaa ctatttataa aacaaagtga tctaattgtt
    20401 gcaaatagat gggatagggg ccttgaagct tataaagata aagtttacac aagggggatc
    20461 tggataagag attaactatt gatattaaaa aggcaataat ttataaaatt tgtacaaaaa
    20521 aatgttaaat tttcacattt tcatagtata ctgtttaata gaaagtaggt tctttgtaac
    20581 cgctccatta taaaatcctt tcactcttcc ggtatactat taggaaaaac ataactggag
    20641 gatattttga gctcacacct catcgttcca gtggctgttc cccaagctcg tgtactgccc
    20701 aaaaaagtta gacattctat ttagaacgag gattgagttc tgtattgtac aaggctcggt
    20761 ccttttagag tcagcttaag gctggctttt tcaatcacca aagtgtcaga atgttttgac
    20821 aaatgaacac aaataatgat ataatatgca aaagctagga ggtggtagga tgattgaaaa
    20881 aatggaactg ggggaatttt acaaggaatt gcgcttggcg agaaagctca agcagtcaga
    20941 tgtggcttgt gctggactaa cagcctctca gttgtccaag tttgaactag gacagtctat
    21001 gctgtctgca gacaagctga tcctagccat ccaagggatc aatatgaatt ttgatgagtt
    21061 tgggcacaaa ctcaacaact atcaagaatc tccacatatg cgaattggta gaagggttgt
    21121 ggattgcttt tcccatcagg atatagctgc tttagagcag ctattggagg aagtcgatca
    21181 agaacagatg gcgcagacct atcgtcgttt gaatgccatt gtgattaaaa atgcactcca
    21241 ttccttagat aaaagctacc cgctaacaga ggaggatagc gagtttttga ctacctacct
    21301 ctacgctatt gagtcttgga cctggtttga actctatctt ttttgcaata ctatgccctt
    21361 cttgagcaat caagatctga tctttttatc aacctcctta ctcgaaaaat ccaaggaatt
    21421 taaagagtta gtacacaatc gatggtatat gaaaagtggt tatcttaata tcatctcaga
    21481 acttatggag cgcaagctat tttcttatat tccaatcttt gaagctgagc tggagcgcat
    21541 gctccgtcca tacgatgttt ttgaaaaagt attgtggcag tttttaaaga aaatgcagat
    21601 ttttcttcaa accaaaggaa gcaatcaaaa agagattgaa cactttatcc aatctctgca
    21661 agtattagaa aatccacaat tgacagccct ttttgaattg cgtttgcagc aatacaaaga
    21721 gcttatcgat tagttagaaa tgggaaaaag ataataatat cagcaacgat cgtcaataat
    21781 gttaaaactt gtttcttcat attacttccc tcctcattag taataacttt attataccag
    21841 ggaaataatc aaatctacca aaatcgcaaa tctgaaattt ctataagaaa aaatatcaaa
    21901 tatgcgattt tctaaaataa gccaatttcc gtgttatact gtccttgtaa aacatttgaa
    21961 gcaaatccta ggtcgcagaa gtggtttaca aatgaagata attgaaggag tgtaaaagat
    22021 gttaaattta caatttgcag aaacaatgga attgacagaa gctgagttgc aagatgttag
    22081 aggaggcaac ctcgtaaatt ctatgggagg tggtggaaga agtggtatat ctggttgggg
    22141 cgtcccagga atttaccctg gttggggcaa tcaagggatg agtcctaatc gtggagcttt
    22201 tgattggact atagatttag cagatggatt gtttggccgc cgtagaagat aggctcttat
    22261 aggagataat aggatgaaga aaatgaaaga agtgaaattt cacctagcaa ctggcttgtt
    22321 gattttgact tattacctca tttttaatgt cacatcagac ttagatttta tggttgcttt
    22381 gtctgataat atgtactatg tgttccaagt tttattggta cttattctgg gaactatagc
    22441 tacaattgct tttgtcaaaa gtgaacattg gaaagagtgt ggtcgtttcc agtttcgttg
    22501 gtcttacctg ggtgttttcc ttctttcttt tttcttattg ttcgtgtggg caaatctaac
    22561 aacctatatc tttcctcgta cccagaatgg aagtacagtc gtagaagtag ccaccagttt
    22621 aacaggaatt agctattttg ttacgcgaat actttatact agtattatcg cacctgtatc
    22681 agaagaggtt gtttgtcgtg gtcttttgat gacaagttta tctaaagtta agagatacta
    22741 tcttgatgtt cttgtttccg ctgccatatt tggcgctatg catgttttgc agtatggttg
    22801 gataacgaca gatttcataa agtattttgg aatgggcttg atattttgta tgatgtttcg
    22861 ctacacccga tccatctatt gggctatagc tctgcatgct tcatggaata gcttcttact
    22921 cattgttact ttattggtat ttggatatta gaaaggtgat atatgaaaaa gataatctca
    22981 caccgctact ttattatagt ttttctacta gttattgctg accagaagtt cagtgtttta
    23041 gttttacgca gcgaccttgt tgctgggcta tctgactttg cctattatct gtcggatatg
    23101 atgttgaatt ttcttgtggt tttatttgct cttattgcta tgatttggtc ggggaaatgg
    23161 cagaaaatca atagtagaaa gtttaaagga tcctatcttt tctattcctt cctagctctg
    23221 cttgcttttg ttgcttggaa ttttgtcacc ttttttcttt tcccacctac tcgaaatgaa
    23281 atttcttatc aacatgctgc tcctactttt acaggagcta cggcattttt gatgtatttt
    23341 ttttatcctg tgattgcagg tcccattttt gaagacatga tttatcgtgg attggtgatg
    23401 acagctctgg aaaaaggaaa gaaatggggg ctagatgtac ttggttctgc tattttattt
    23461 ggggtctcgc acattagtaa tcacggttgg gtcttgacag actttttcgt ctatatgggt
    23521 ggcggactta tatttgcagt cttatttaga atgacaaagt ccatttattg gcctattggg
    23581 ctgcatatag tctacaacgg cattggtcag cttttgatgt tactgtaatt ttggttgtta
    23641 gtagtatcgc ggtctatttc tggggaaaga ttcccatttg aacttaagaa ggagttgtga
    23701 tgaaagtatt tcttcaaaat agagatttta ggcaattaac tatcaaccag tggatttcaa
    23761 cgcttgggga tacgattttt tatctggcct tcctgaatta tgtggcagat gcgtcttttg
    23821 cccctttggc gattttactt atcacgattt cagaaaccct tccccaagtt ctacaaatct
    23881 ttctgggagt tttggcggat tttcaacatc atcgtgtctt gaaatacaca gtcattagtt
    23941 ttacaaaatt tttgctttac tctatagtgt ccctatcgct ttcagggcag tctttttcct
    24001 tgttgctagt aacctttatt tgtctgctta acctcttgtc tgacacattg agttattttt
    24061 caggcgccat gctcactccg attttcatta gaattattgg gcaagaccat ctggcagaag
    24121 ctattggatt taaacagtca actgttagtt tagtgaaaac aatcagtaat atcctaggag
    24181 gagtcttact aggcattcta tccatccagt ttatttcctt actgaacgct cttacctttt
    24241 taatcgcatt tttaggtatc ctcttcataa aaactgacct cttgaaagta gaaaaaacga
    24301 ttagctatca agaaggactc tctgtaaaat ccttttgcca gcatttgctc caatcatcga
    24361 aattgatatg gaatatgaat aaggtgctct tggttttgtt tattatctct actagtcaag
    24421 cagtgataaa tgttacggtt cctatttcca ctctattttt aaggaaccag ccctttttga
    24481 atttacaaac tggtcaatct cttgccttgt tagccacact agaattatca gcccttattt
    24541 tgggaagtct gatgagtggc tatctgcaac ataccatttc cataaaaata gccctgtatg
    24601 cttcactcct actccaatta ctactcctag tgggctttgc gacagctcat tttggcttga
    24661 ttctgatctt tagctttttg gatgcctttt tcgcgggtat tctctctcct agattgcaag
    24721 aactcgtctt taaacaaata cctgaggagt caatgggagc agttcaatct tctatcggtg
    24781 ccattacggt tgttttacct agcttattta caatagcttt gggaaccatt gctactagct
    24841 ttggaactct ggcagttagc tttgttttat tactatttct tctagttgcc tttgtcatgc
    24901 ttctgaatat tcgtgaaagt atttagtgga gaatttctat aatatatgtt tgagactgga
    24961 ttgccagtct ttttatgatg gtcaaaatca acagactttt tctcttttct gaatgtgtta
    25021 tagtagactg aatctaaaat agtacgaaat aattgctaaa acatttatag aaattaattt
    25081 tactttccca atcgatttgt tctcatctta tttcaatctg ctatataata gtccatgctg
    25141 tggctggatt cttttcagcc tacttatact cttcgaaact ctcttcaaac cacgtcagct
    25201 tcaccttgcc gtaggtatgg ttactgactt cgtcagttct atccacaacc tcaaaacagt
    25261 gttttgagct gacttcgtca gttctatctg caacctcaaa acaatgtttt gagcaacctg
    25321 cggctagttt cctagtttgc tctttgattt tcattgagta ttattaagac aatatgagga
    25381 gaaagatgaa agaaaaagga ttttaggagg gggcgcaggc agccatgcca acggctcttg
    25441 gctatgtcag tatcggcctg gcctgtggga ctatcggtgc gccctatgtg acacctgttg
    25501 agatgggctt gatgagtctc tttgtttatg ctgggagtgc ccagtttgcc atgttggcac
    25561 tgattgtggt tcaagctcct gtggcagcta ttgctatgac ggtttttcta atcaacttgc
    25621 gtctcttttt gttgagttta cacgcatcga cttatttccg tcataccagt ctttggtaca
    25681 atatcggtat gtctagtatc ttgacagatg agacctatgg cgttttgatg ggtgaattgg
    25741 cccatacaga caaggtaaat cctatgtgga tgcacggaaa caatcttaac agctatgtgg
    25801 cttggtttgt ggggacagta gtcggaacgg ctctgggtgg cctgctacca aatccagaaa
    25861 tctttggctt ggattttgcc ctggttggga tgtttattgg tatttttgct tcgcaatttc
    25921 agattatgca aagacggatt cctgtccgca atctgctcat tatcctagca gttgttgcgg
    25981 tgtccttctt tttgctcttg acagtggtgt ctcagtcact agctgttctg tttgcgacgc
    26041 tacttggttg tagcatgggg gtggttttag atggtcagta agtatctttt attagcagtt
    26101 attttctctg acttggtgac ttggattctc cgtatgattc ccttcatctt agtcaagtat
    26161 aagggcttgc ctgcaatcgt tgagcgtttt ttgaagttct tgcccgtttc cattatcttt
    26221 gccttgattc tttcaagcgt agtgacaggt aaggttggga gccttcctca aattaaatgg
    26281 ctagacttct tagccgtctt tccaacagct tgggtagcct ttcgctaccg caatctagtc
    26341 ggaacagttc tctttggagt agtcttgatt gccgtcttgc gtttggtctt ttaaatcagc
    26401 cataaagaaa acctatcaca gatatatata tcatataatg gtgtaaatga tttttttctg
    26461 ttaagattat aaggtattct attttggagg aaatgacatg aaaaaaatcg ttaaatactc
    26521 atctcttgct gccctagggc ttgttgctgc aggtgtgcta gcagcttgct ccggtggtgc
    26581 taagaaagaa ggacaagcag ctagcaagaa agaaattatt gttgcaacta attcttcacc
    26641 aaaaccattc aactatgaag aaaatggcga attgactggt tacgagattg aagtcgttcg
    26701 cgctatcttt aaagactctg ataagtatga tgtcaagttt gagaagacag agtggtcagg
    26761 tgtctttgcg ggtcttgacg ctgaccgtta ccaaatggct gttaacaaca tcagctacac
    26821 taaagaacgt gcggagaaat acctttatgc agccccaact gttaaagacc ctaacgttct
    26881 tgtagtcaag aaagacgatt ctagcatcaa atcgcttgat gatgttggtg gaaaatcaac
    26941 agaagttgtt caaggaacaa catctgctaa acagttagaa gactacaaca aacaacactc
    27001 agataatcca actatcctta actatactaa agcaaactta caacaaatca tgggccactt
    27061 gagcgatggt cagtttgact acaagatttc tgataaaatc actgttgaaa cagtcatcaa
    27121 gaaccaaggt ttggacaact tgaaagtcat cgatcttcca agcgaccaac aaccttacgt
    27181 ttacccactt cttgctaaag gtcaagatga gttgaaaaca tttgtagaca aacgtatcca
    27241 agaactctac aaagacggaa ctcttgaaaa attgtctaaa caattcttcg gagacactta
    27301 cctaccggca gaagctgata ttaaataatt tcttgaaatc atccattctg agtaagatgg
    27361 gtgatttttc agttcgctac cgcaatctag tcggaacagt tctctttgga gtggtcttga
    27421 ttgccatctt gcgtttggtc ttttaaatta cccataaaaa aaacttatca cagagataga
    27481 tatcatataa tggcgtaaat gctctttttc tgttaagatt ataaggtatt ctattttgga
    27541 ggaaatgaca tgaaaaaaat cgttaaatac tcatctcttg cagcccttgc tcttgttgct
    27601 gcaggtgtgc ttgcggcttg ctcaggtggt gctaagaaag aaggacaagc agctagcaag
    27661 aaagaaatca tcgttgcaac caatggatca ccaaagccat ttatctatga agaaaatggc
    27721 gaattgactg gttatgagat tgaagtcgtt cgcgctatct ttaaagattc tgacaaatat
    27781 aatgtcaagt ttgaaaagac agaatggtca ggtgtctttg ctggtcttga tgctgaccgt
    27841 tacaatatgg ctgtcaacaa tcttagctac actaaagaac gtgcggagaa atacctctat
    27901 gccgcaccaa ttgcccaaaa tcctaatgtc cttgtagtga agaaagatga ctctagtatc
    27961 aagtctctcg atgatatcgg tggaaaatcg acggaagtcg ttcaagccac tacatcagct
    28021 aagcagttag aagcatacaa cgctgaacac acggacaacc caactatcct taactatact
    28081 aaggcagatt tccaacaaat catggtacgt ttgagcgatg gacaatttga ctacaagatt
    28141 tttgataaaa tcggtgttga aacagtgatc aagaaccaag gtttggacaa cttgaaagtt
    28201 atcgaacttc caagcgacca acaaccgtac gtttacccac ttcttgctca gggtcaagat
    28261 gagttgaaat catttgtaga caaacgcatt aaagaactct acaaagacgg aacgcttgaa
    28321 aaattgtcta aacaattctt cggagacact tatctaccgg cagaagctga tattaaataa
    28381 tttcttgaaa tcatccattc tgagtaagat gggtggtttc tcagttttta gggatatagt
    28441 tttaaactat atatctgact atctaataac aatttgtgaa atcaaacaaa ttgtgagata
    28501 ctagtacggt attattttta aggagaaaga atcatgaaaa tcaaaaaatg gcttggccta
    28561 gcagcccttg ctacagtcgc aggtttggct cttgcagctt gcggaaactc agaaaagaaa
    28621 gcagacaatg caacaacgat caaaatcgca actgttaacc gtagcggttc tgaagaaaaa
    28681 cgttgggaca aaatccaaga attggttaaa aaagacggaa ttaccttgga atttacagag
    28741 ttcacagact actcacaacc aaacaaagca actgctgatg gcgaagtaga tttgaacgct
    28801 ttccaacact ataacttctt gaacaactgg aacaaagaaa acggaaaaga ccttgtagcg
    28861 attgcagata cttacatctc tccaatccgc ctttactcag gtttgaatgg aagtgccaac
    28921 aagtacacta aagtagaaga catcccagca aacggagaaa tcgctgtacc gaatgacgct
    28981 acaaacgaaa gccgtgcgct ttacttgctt caatcagctg gcttgattaa attggatgtt
    29041 tctggaactg ctcttgcaac agttgccaac atcaaagaaa atccaaagaa cttgaaaatc
    29101 actgaattgg acgctagcca aacagctcgt tcattgtcat cagttgacgc tgccgttgta
    29161 aacaatacct tcgttacaga agcaaaattg gactacaaga aagcactttt caaagaacaa
    29221 gctgatgaaa actcaaaaca atggtacaac atcattgttg cgaaaaaaga ttgggaaaca
    29281 tcacctaagg ctgatgctat caagaaagta atcgcagctt accacacaga tgacgtgaaa
    29341 aaagttatcg aagaatcatc agatggtttg gatcaaccag tttggtaata agaaacaggg
    29401 aggtgggaga gaaaattcca cctcttgctt ttgtatagag tatagattgt aaagaagact
    29461 attcgttcat agaaaggtag agagaatatg gtttttccta gcgaacaaga acagattgaa
    29521 aaatttgaaa aggatcatgt agtccaacat tattttgagg ttttgcgtac cttgatttct
    29581 aagaaatcag tctttgccca gcaggttgga ctcaaggaag tcgcaaatta tctgggtgag
    29641 attttcaagc gtgttggagc tgaagtggag attgatgaga gctatacagc gccctttgtc
    29701 atggcacatt tcaagagttc gcgtccagat gccaagacct tgattttcta taaccactat
    29761 gacactgtgc cagcggatgg ggatcaggtc tggacagagg atccttttac gctttcggtc
    29821 cgcaatggct tcatgtatgg gcgtggggtt gatgacgaca agggtcatat cacagctcgc
    29881 ttgagtgctt tgagaaaata tatgcagcac catgatgatt tacctgtcaa tatcagcttt
    29941 atcatggagg gagcggagga atcggcttca acagacctag ataagtattt ggaaaagcat
    30001 gcagacaaac tccgtggggc ggatttgttg gtctgggaac aagggaccaa aaatgccttg
    30061 gaacagctgg aaatttctgg tggcaataag gggattgtga cctttgatgc caaggtaaaa
    30121 agcgctgatg tggatatcca ctcgagttat ggtggtgttg tggaatcagc tccttggtat
    30181 ctcctccaag ccttacagtc tcttcgtgct gcggatggcc gtatcttggt tgaaggcttg
    30241 tacgaagaag tacaagagcc caatgaacga gaaatggcct tgctagaaac ttatggtcaa
    30301 cgaaacccag aggaagttag tcggatttat ggattggagt tgcctctctt acaggaggag
    30361 cggatggcct ttctaaaacg tttctttttc gagccagcgc ttaatatcga aggaatccag
    30421 tctggttatc aaggtcaggg tgttaagact attttacctg cagaagccag tgccaagcta
    30481 gaggttcgtc tggttccggg cctagaaccg catgatgttc tggaaaaaat tcggaaacaa
    30541 ctagacaaaa atggctttga taaggtagaa ttatactata ccttgggaga gatgagctat
    30601 cgaagcgata tgagcgcacc agccattctc aatgtgatcg agttggccaa gaaattctat
    30661 ccacagggcg tttcagtctt gccgacgaca gcggggacag gacctatgca tacggtcttt
    30721 gatgccctag aggtaccaat ggttgcattt ggtctaggaa atgccaatag ccgagaccac
    30781 ggtggagatg aaaatgtgcg aatcgctgat tattacaccc atatcgaatt agtagaggag
    30841 ctgattagaa gctatgagta gagatattat caagttagat cagatcgatg tgacttttca
    30901 ccaaaagaag agaaccatca cagcggttaa ggatgtgacc attcacatcc aagaagggga
    30961 tatctacgga atcgttggat attctggagc agggaaatca acccttgtac gggtgattaa
    31021 cctcttgcaa aaaccatctg cagggaaaat taccattgac gacgatgtga tttttgatgg
    31081 taaggtcacc ttgacggcag agcagttgcg tcgtaaacgt caagatatcg ggatgatttt
    31141 ccagcatttt aacctgatga gccaaaagac agcagaggag aatgtagcct ttgcccttaa
    31201 acactctgga ctcagcaagg aagaaaagaa ggctaaagta gctaagttgt tggacttggt
    31261 tggtttggca gatcgtgctg aaaactaccc ttcacaacta tctggagggc aaaaacagcg
    31321 tgtggcaatt gcgcgtgcct tggccaatga tccaaaaatc ttgatttcag acgagtcaac
    31381 ttctgccctt gatccgaaga caaccaagca gattttggcc ttgttgcaag atttgaacca
    31441 aaaattaggc ttgactgttg tcttgattac gcatgaaatg cagattgtca aagacattgc
    31501 caaccgtgtt gcagttatgc aggatgggca tttgattgaa gagggtagtg tgcttgaaat
    31561 cttctcaaat cctaaacaac ctttgactca agactttatc tcaacagcta caggtattga
    31621 cgaagccatg gtcaaaatcg agaagcaaga aatcgtggaa cacttgtctg aaaacagtct
    31681 cttggtgcaa ctcaagtacg ctggagcttc aacagacgag ccacttttga atgaattgta
    31741 caagcattac caagtaatgg ctaatattct ctatgggaat atcgaaattc tcgatggtac
    31801 tcctgttgga gaattggtgg tggtcttgtc aggtgaaaaa gcagcgttgg caggtgccca
    31861 agaagccatt cgtcaagcag gtgtacaact aaaagtattg aagggaggac agtaagatgg
    31921 aatcattgat tcaaacctat ttaccaaatg tctataaaat gggttgggct ggtcaggcag
    31981 gctggggaac ggctatctac ttaactcttt atatgacagt tctttccttc attatcggag
    32041 gcttcttggg gctagtggca ggtctctttc tcgtcttgac agcgccaggt ggtgtcttgg
    32101 agaataaagt cgtattctgg attttagaca aaattacctc aatttttcgt gcagttccct
    32161 ttatcatcct cttggcaatc ttgtcaccac tttctcactt gattgttaaa acaagtatcg
    32221 ggccaaatgc agcccttgtc ccactttctt ttgcagtctt tgccttcttt gcccgtcagg
    32281 tgcaggttgt cttggctgaa ttggatggcg gtgtcattga ggcggctcaa gcgagcggag
    32341 cgactttctg ggacatcgtg ggtgtttacc tatcagaagg tcttccagat ttgatccgtg
    32401 tgacgactgt gaccttgatt tcccttgttg gggaaacagc tatggccggt gcggttggag
    32461 ctggtggtat cggtaacgta gccatcgctt atggatttaa ccgctacaat cacgatgtga
    32521 ccatcttggc aaccatcatt atcattttga ttatctttgc aatccaattc ttgggagatt
    32581 tcttgactaa gaaattgagc cataaataaa aaagagccgc gtggctcttt ttaactgatc
    32641 agattttctg tgcaaatttt ttactcaagg cttgtccaat caaggcaccc actagggctc
    32701 cgatgacaat acttgcgata aatagaagga cagttccagg gtttggagcg accatgatgc
    32761 ggtcgatata ttcttgggat tttcctcttg ccagaagagt agccatatag gctttgggcg
    32821 caatccacat aagcaagatt ggtcctgttg tactaaaggc gaaaataatg aaagaaagga
    32881 agttctttgt tttgtccttg tattttccta aatgagctac tccatctgct aggaggccac
    32941 agataattcc aggaaggaag gaaccagcac cgtgtttagt tcccaagaaa aagagggcaa
    33001 tgacaaggcc gatagtggta atggctccaa agcgcggaac ttttgcgact aggatcatat
    33061 agacgctacc gccgacaagg gcagtaaagg caggcgcata aaacatgttt ccagtttggt
    33121 caaagagatt gcccaaaagg acaccaatcc ccatgcagag gaagtaaaga actgcaaaaa
    33181 gcagtgtagt taagatagat ttcttcatga attgtctcct gataattttt tcacaattct
    33241 cattttacca tggtttggtg ggattgtaaa tggatactag aagtttttga aaacgcttga
    33301 aatatgatat aatggtttca tagttatttt taggggaata tcatgggtag atttttagac
    33361 tttgtcttta atcgtttctt tttagggatg attgcgacag ccttcttttg gctattaact
    33421 ttagcaggag ggattatcct tggtctagcg ccggctagtg ccaccttgat gagcttatat
    33481 gcagaacatg gttatagctt tcgggaatac agtttgaagg aggcttggtc tctttacaag
    33541 caaaattttg tctcaagcaa cctgattttc tatagctttt taggtgtggg tctagttttg
    33601 acctatggtt tgtatctctt ggtgcaattg cctcatcaga ctattgttca tttgattgcg
    33661 acccttttga atgtcctagt agttgccctg atctttttgg cttatacagt atctttaaaa
    33721 ttacaagttt attttgcctt gtcctatcga aatagtctca aattatcctt gattggcatc
    33781 tttatgagtc tagcagctgt ggccaaggtt ctccttggga ctgtgctact tgtagcaatt
    33841 ggttactata tgcctgccct gctatttttt gtaggaattg ggatgtggca tttctttatc
    33901 agtgatatgt tggaacctgt ctatgaaatc atccatgaaa aattggcgac aaaatagaat
    33961 gaagcagttt tggctacata cgcttctaag aacctatagt tcagtgatga tcattatcat
    34021 tgcgagtttt gcaatcttac tctcttacgc tgactgggat tcacgtgaaa aggaagccca
    34081 gagagtagcc cagcgtgtaa ctgctagaac agtgagtgaa attgaatatt accatagaga
    34141 gtcaacccag atagctcagg ctttagttga aaatcaagct cgtattgagg gaatctataa
    34201 atactttagc cttagcatgc cagactattt ttactggcaa ttagagcgga aagcttcgcc
    34261 ttatatatca gtctctctgt atgaaaatgt tgatgacctc tatgttcgaa atgattttgt
    34321 aactggggtg gccattgctt ttcaagatta caaggaagtc tatgtttcta ctaaagacaa
    34381 acgtagtgga gaaaaaatca gggctgagga tttcaaacca gcaggaaata gttttgccat
    34441 tccggtgtca gatccagtgt cagatcaaga tttaggagtg atttacatct ccttggatcc
    34501 tgctgtttta taccatgcca ttgataatac tagaggtcat actccgatgg cagtaacagt
    34561 gacctcacct tttgatacgg agatttttca tattggtgag acagttgata gggagagtga
    34621 aaattggcta gttggcttaa cttctcatgg atatcaggtt caggtggcag ttcctaaaaa
    34681 ctttgtttta caaggaacag tgactagctc tgctttgatt gtgggtttga gccttctctt
    34741 tattgtcatt ctttatctga ctttgaggca gacttttgct aattaccaaa agcaggtagt
    34801 ggatttagtg gaatccattc aagtcattgc tcaaggcgaa gaggggcgtc ggattgacat
    34861 ttccgaaaaa gatcaggaat tactcctaat cgcggagacg accaatgata tgttggatcg
    34921 attggaaaag aatatccatg atatttacca gttagagctt agtcaaaaag atgccaatat
    34981 gcgagccttg caggcgcaaa tcaatcctca ttttatgtat aatacgctgg agttcttgcg
    35041 catgtatgca gttatgcaga gtcaagatga gttggcagat atcatttatg aattcagtag
    35101 tctcttgcgt aacaatattt ccgacgaaag agagaccctc ctcaaacagg aattagaatt
    35161 ttgccgtaaa tacagctatc tctgcatggt tcgctatccc aagtccattg cctatggttt
    35221 caagatagat ccagagttag agaatatgaa gattcccaag tttaccttgc aaccgctggt
    35281 agaaaactat ttcgcgcatg gtgttgacca caggcggaca gataatgtga ttagcatcaa
    35341 ggctcttaaa caggatggtt ttgtggaaat tttggtggtc gataatggta gaggaatgtc
    35401 ggctgaaaag ttggcaaata tccgagaaaa attaagtcag aaatattttg aacaccgagc
    35461 cagctacagt gatcaaaggc agtctatcgg gattgtcaat gtacacgagc gttttgtgct
    35521 ctattttgga gaccgctatg ccattacgat agagtctgca gagcaagccg gtgttcagta
    35581 tcgtattaca attcaagatg agtagaaagg gagaaaatgt ataaagtatt attagtagat
    35641 gatgagtaca tggtgacaga aggtctgaag cgtttgattc cctttgataa gtgggatatg
    35701 gaggtcgtcg caacagccag tcatgccgat gaagctctag aatatgttca ggaaaatcct
    35761 gtcgatgtca tcatttccga tgtcaatatg ccagacaaaa cagggcttga tatgattcgg
    35821 gagatgaaag agatcttacc agatgctgcc tatatcctgc tctcaggtta tcaggagttt
    35881 gattatgtaa aaagagcaat gaaccttagt gtggtggact atttggtcaa gcctgttgat
    35941 aaggtagagc tgggaaatct gctggagaag attgcaggtc agctcggcga gagagggaag
    36001 aaaagtcaga ctcttagtca agaattagac gaggctggat ttgttagtta tttaggggat
    36061 aaggagaatt ggtggatagg tctatccaag gaaaaacaag gttccttcac cattccctac
    36121 tatgtcttgg gccaagactg gcagattttc atttctgacc aacccctaga tggtttagtc
    36181 gttacacctt ttgaagctcc ttatcaagaa cactttgaac gctggaagct gaatgctgag
    36241 aaaaccctct tttacggttc tgtaaatttg cagcagtctg agagtctctt tgcctattac
    36301 gaaccgattt atagggttat cattcaggga aatctcaatc aaatcgtaga agagttaaat
    36361 ctcttggaga aggtagttct tgaaaatacg ccgcgtgttc cgattactaa acagcttttt
    36421 attcagtttg tcatggatgt tttccattta tttgaacatc tcaaagctga tgacctgaca
    36481 gacatcgtca aaaccattca tgctattcaa tccttcgatg aattggttcc ttatatcaag
    36541 gaaactctga gcagcttttt cggtcaatac cgtatgaatg aaaatgtggt cagtgtgctg
    36601 gaagtcattg gttgtgatta ccaaaaagag ctttccctca aggatatcag taaggctctc
    36661 tttatcaatc ctgtctatct agggcagttg attaagcgtg aaaccgattc gacttttgca
    36721 gagttactaa acaaacaacg tattaaggct gcccaacaac ttttgctttc aactagtgac
    36781 agcatcgaag atatttgtta tgctgttggt tacagtaacc ttggatattt ctataaagtt
    36841 ttccgaaaat tgtgcggaaa atcgccaaaa gcctaccgaa aacaggtaga aactatacta
    36901 taagatttgt attcctttac aaaatgtgct ataatataaa tattattatt aggaggttct
    36961 atcatgaaaa agaaaccaat ttatctatgg gtcttgctaa tcttgtctgc ccttatttca
    37021 gttccgtctc tgtttggaat tgtgagtccc ttgcctagta aagaagccct tcgtactgct
    37081 cagaaacaag ttgcaggggt caatgctcag caattagaag accagcttaa ttatacctat
    37141 agagtagcag aagcatctca ttctattttt aatgttgctt tgattgtgct atctactatt
    37201 ttagtggtcg tagcgattgt cttccttgtt cgtaaaaatt tgcaatatgc aaactatact
    37261 tacgttggct atgttttgtt agctattatt ggttcgattt atggctatgt tggtttacaa
    37321 gacgctgtgc agttggttca agatgagagc atgcgtttga cagtgagtat tggttcaaaa
    37381 gctgttagca ttttctatat cgtcatcaat gttctcttcc tagcccttgt cttctataag
    37441 atgtggcgac aacagaaagc ctcggcagaa gaagaggaaa cagaagagct tgcctaagta
    37501 ttgacaaaaa agaactatca agatacaatc ttggtagttg ttttttgatt atagataaaa
    37561 tcatggaggt acatatgaag ataatttctt tagtttatat tagtttgagt ggcaacactg
    37621 aaagttttgt gacgcgcttg aaagactatc tcttgtccca gtacaaaggg attgaggttc
    37681 aaaagattca tatcaaggat ttagtcaagg aaggcaaaaa tttctatgaa atggaccatc
    37741 cctatgtcgc ttttttgccg acctatctcg aaggtgggaa tggcgtggat aacggagatg
    37801 ttgagatttt gacgacaccg gtgggagatt ttattgccta tggtaacaat gctagtaagt
    37861 gttttggtgt ggttgggtca ggaaatcgta actttaataa ccaatactgc ctaacagcca
    37921 agcaatacag tcaacgcttt ggctttcctg tattggctga ctttgaaatg cgaggcatgc
    37981 tggaagatat caaacatgtc gcagctatta tcgcagattt gtatgagttg gaaaaggaga
    38041 attaatactc aatgaaaatc aaagagcaaa ctaggaagct agtcgcaggt tgctcaaagc
    38101 acagctttga ggttgcagat agagctgacg tggtttgaag agattctcga atagtataaa
    38161 attcttataa gaggtggttg aagttgttca actgtttttt gagtataaac agtctttaag
    38221 aacgtaaaaa agcataagtt caggtcttca aaaccttgtt cttatgcttt ttatcataga
    38281 aatatttgct gaattttctc ttgaaatgaa accttatctt catctcgcgc ttgtccctta
    38341 ccctgctttt ccgattgcga gtgcgtagat aaagaagatg gcgaagccaa agaggaaaat
    38401 caatcccgca atggcaaggt gtttgagcca agaaggaaga tttttgtttt cacgcgttac
    38461 caaggcgtaa ttcaaaagag caaagaaagg tgttgtcagg aaagagccaa tcatggcaaa
    38521 gcggagcatg gttgaaacct gaccagagaa gaacttgata atgacgatac cgatgatagc
    38581 agtgatggtc atccagatgt tcaaagattt acgattgtcc tctttttgac tgattagcag
    38641 tcggagagat tcctgattaa cgcgagaata gccatcgata acagttataa ctgttccaaa
    38701 gatacagagg aaggcaataa aggtaatcaa gtaacgggac cattcgccaa gaacagaggc
    38761 atacatgccc acgaattgag agatgtattt ggctgaagca gcttcaaccg cctgccctgt
    38821 aggatactga atcagtgctc ccagtgccac aaagaagacg gctaggatag ctgttccaat
    38881 ataaccagtg ttaaagtcaa acagagcgtc ttctgtgtta aagttgacgg tctttctctt
    38941 ttcagctgac caaagtgaat tgatggctga aatttcaata ggagccggca tccatcctag
    39001 gagggagacg atgaagggca gagctgccat ttgccaaggt gtcttctcga caaaatcaga
    39061 actgtattct ggatgcttga ccgccgcaat gataactgcc agaacagtcg caatggttaa
    39121 ggcagacata atccatttga ccatgccgtc taaaagtttg tagcctccaa agagtagcat
    39181 agcccaaatg attgcaacga gaatgaggga ccactgagta atgctaagtc caatcattgg
    39241 gaaggcactg gcgatgatag ctgagcacag aatggcaaca ccagccgtgt tgaccatagc
    39301 cgaaaagaca ttgaggataa agaaaatcca gagatagagt tttccttttt cggcataacc
    39361 ttcaaccaaa gtctttccag tatcagctgt gtattcagca ccaaaacgga aaaatggata
    39421 tttaaagaca ttggctaaga tgaccaagag aagtagagac caaccgtaag aaccgccagc
    39481 ttgagttgag gatacaatgt gggaacctcc aacagcggca gttgccatta ggattccagg
    39541 tcccattgct tttagcttgc ttgcccaggt tgattgattt aaggaaatag cttgcgacat
    39601 gataaatact cctttttgaa ttttcagaat aatctgtata tgtaatctat attctacaaa
    39661 aaattttgga aaaatgcaag aatattttga aaaaagatag aaaatttaca aagaaaat
//
LOCUS       DAVBDR010000013        37452 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.013, whole genome shotgun sequence.
ACCESSION   DAVBDR010000013 DAVBDR010000000
VERSION     DAVBDR010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 37452)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37452)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37452
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.013"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            complement(<1..777)
                     /locus_tag="VQ540_000702"
     CDS             complement(<1..777)
                     /locus_tag="VQ540_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET2544538.1"
                     /translation="MSKETVVYTKRREKIKDNILGYSFLAPALILLGIFLVIPVGMVI
                     YYAFTDYYLLTPDERKFVGLENFIRLTKDPIFLKSFLNTLKFVVWIIPVQLGAALGMA
                     LIVNKKRKGNMFFKVAFFAPVVMSLVVISILWLYLLNPNSGLLNAILNKVGIASQPFL
                     TSPKQAMYAIVFVSAWQGAGYQMLLFLGGMQNIPQDVYEAAELDGFSKWAQFRYITMP
                     LLKPTALFVLLTTLISAFKLIVQPMVMTQGGPLNSTITMVY"
     gene            complement(873..2183)
                     /locus_tag="VQ540_000703"
     CDS             complement(873..2183)
                     /locus_tag="VQ540_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HET2544539.1"
                     /translation="MRKGTMLSVVAGLSLAILAGCSGGTNSKQASSSNDIKVWVQFSD
                     ETNEGKAWQKVVDNFNQSGKSKYKVVTEYIPRSGSGGGYEDKVNAAITTNSLPDVITL
                     DGPNTAAYAKSKVITPLDDYLKDNNMDDVLDSIKQQGTYNGKFYAFGFSESNVGVYYN
                     KKMFKEAGIAESELPTLEKPWTWDEFNTIAKKLKDHYNKPAIDFRINSNDEMLPYAYM
                     PLIWSNNGSVVNEDGTKAEGYFNSKESVEAVQFIQNLVKEGYTTVSPVEKGFETGEYP
                     MLLSGSWTIADMNTNYKDIDFGILPYPVSSKTKKLVSPSGSWQLAVTTKSDKKEAASE
                     FVKFATNTESSEIISLGNSVLPIRKSTIENIKDKVSEPMRFLMEQNSKTAHARPVVVA
                     YPQVSRAFQQAMQDISYYEENPNVQKVLDTRTKEMQTAIDQSLK"
     gene            complement(2310..3305)
                     /locus_tag="VQ540_000704"
     CDS             complement(2310..3305)
                     /locus_tag="VQ540_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HET2544540.1"
                     /translation="MVEQRKSITMKDVALEAGVSVGTVSRVINKEKGIKEVTLRKVQR
                     AIKTLDYIPDNYARGMKKNRTETIALIIPSIWHPFFSEFAYHVEKELLKYNYKLFICN
                     ADSDSQNEIEYIEMLKQNKVDGIIGITYSDIDKYILSDLPFVSIDRHFSENVCYVTSA
                     NYKGGQTAAEELVRRDNKHLAFIGSINMYENETILRSKGFREKAKELGVDVYNFEMKE
                     PLINPEDQIRIFLQSHKEIDGIFTINDMMALRVISVMKELGKIAPDDYQIIGFDGLKT
                     SVDQSYLVSTIVQDIGMMAKESVAMILKMIKREEILEKRIVIPTYFGGDKTTKKI"
     gene            complement(3667..5148)
                     /locus_tag="VQ540_000705"
     CDS             complement(3667..5148)
                     /locus_tag="VQ540_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001205273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET2544541.1"
                     /translation="MRDLLSKKSHRQLELLELLFEHKRWFHRSELAELLNCTERAVKD
                     DLSHVKSAFPDLIFHSSTNGIRIINTDDSDIEMVYHHFFKHSTHFSILEFIFFNEGCQ
                     AESICKEFYISSSSLYRIISQINKVIKRQFQFEVSLTPVQIIGNERDIRYFFAQYFSE
                     KYYFLEWPFENFSSEPLSQLLELVYKETSFPMNLSTHRMLKLLLVTNLYRIKFGHFME
                     VDKDSFNDQSLDFLMQAEGIEGVAQSFESEYNISLDEEVVCQLFVSYFQKMFFIDESL
                     FMKCVKKDSYVEKSYHLLSDFIDQISVKYQIEMENKDNLIWHLHNTAHLYRQELFTEF
                     ILFDQKGNTIRNFQNIFPKFVSDIKKELSHYLETLEVCSSSMMVNHLSYTFITHTKHL
                     VINLLQNQPKLKVLVMSNFDQYHAKFVAETLSYYCSNNFELEVWTELELSKESLEDSS
                     YDIIISNFIIPPIENKRLIYSNNINTVSLIYLLNAMMFIRLDE"
     gene            5591..5755
                     /locus_tag="VQ540_000706"
     CDS             5591..5755
                     /locus_tag="VQ540_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HET2544542.1"
                     /translation="MGIIANVFAGLVGAYAGQSLLGSWGPSIAGMALLPSIVGAAIVI
                     TVVSFFTGRK"
     gene            5839..6405
                     /gene="amaP"
                     /locus_tag="VQ540_000707"
     CDS             5839..6405
                     /gene="amaP"
                     /locus_tag="VQ540_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HET2544543.1"
                     /translation="MSKAKKICFIIFCILILTIFLPVLIDYHQVSDLGIHLLSWRQNS
                     VVEFYLARYVFWGTVVLSTLVLLSILVVMFYPKRYLEIQLETKNDTLKLKNSAIEGFV
                     RSLVSDHRLIKNPTVHVNLRKNKCFVHVEGKILPSDNIADRCQIIQNEITNGLKQFFG
                     IERQVKLEVAVKNYQPKPQNKKTVSRVK"
     gene            6417..6587
                     /locus_tag="VQ540_000708"
     CDS             6417..6587
                     /locus_tag="VQ540_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HET2544544.1"
                     /translation="MEWLKQYRYPIIAGLIGVFLACLIVSFGFFKTIFVLILGALGVA
                     AGLYIEKNYIDK"
     gene            6626..7234
                     /locus_tag="VQ540_000709"
     CDS             6626..7234
                     /locus_tag="VQ540_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HET2544545.1"
                     /translation="MSNEKNTNTNVEKKDATVVAHEIKGELTYEDKVIQKIIGLSLEN
                     VSGLLGIDGGFFSNLKEKIVNSDDVTSGVNVEVGKTQVAVDLNVIVEYQKNVPALYSE
                     IREIVSSEVAKMTDLEIVEINVNVVDIKTKEQHEADSVSLQDRVSDVAESTGEFTSEQ
                     FEKAKSGLGSGFSTVQEKVSEGVEAVKGAANGVVSHENTRVN"
     gene            7265..7468
                     /locus_tag="VQ540_000710"
     CDS             7265..7468
                     /locus_tag="VQ540_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HET2544546.1"
                     /translation="MSVEEKLNQAKGSIKEGVGKAIGDEKMEKEGAAEKVVSKVKEVA
                     EDAKDAVEGAVEGVKNMLSGDDK"
     gene            complement(7578..7856)
                     /locus_tag="VQ540_000711"
                     /pseudo
     CDS             complement(7578..7856)
                     /locus_tag="VQ540_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007895264.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            8054..8341
                     /locus_tag="VQ540_000712"
     CDS             8054..8341
                     /locus_tag="VQ540_000712"
                     /inference="COORDINATES: protein motif:HMM:NF033563.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HET2544547.1"
                     /translation="MIVSLKTKSRKAKDMAESIQGWLAQFLVNLFKSITFDCGKEFSK
                     WKDISNHHDSESFFANLGCSRQRRLNEHSNRLLRCHDLPKQTDFNEVSQEF"
     gene            complement(8619..9389)
                     /locus_tag="VQ540_000713"
     CDS             complement(8619..9389)
                     /locus_tag="VQ540_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HET2544548.1"
                     /translation="MVEIIYFLIIIIASGLGSISGMGGGIIIKPLMDSFGYHSVSDIA
                     FYSSFSVFIMAIISTIKRFSQSKEIKWRLIFTVSFSSVLGGFLGHLIFQVLLSQLSVR
                     LVSIVQMILLFVMLLVSFVLTDFKKTYQFDKIGFYMICGLLLGLISSFLGIGGGPLNV
                     SLLMVFFSISIKEATMYSLAIIFFSQLSHLATIVVVTGLNQYHLAPVPVIFLASICGG
                     VLGTVVSKVLPENWVRYCFKGMLFFVMGMTLYNLFHIL"
     gene            complement(9404..10252)
                     /locus_tag="VQ540_000714"
     CDS             complement(9404..10252)
                     /locus_tag="VQ540_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formylglycine-generating enzyme family protein"
                     /protein_id="HET2544549.1"
                     /translation="MKMKKIKGGTFMMGTNSEEGFLDDFEGPQVAVSVKDFSIADTPV
                     TNQEFAQFVKETGYKTLAERQEWSFVFILFVPEAEREGYPHPAGAPWWLQVPNACWKH
                     PYGENSNLVGLEDHPVVHVALEDALAFCNWSGMSLPTEAQWEYAARGGRQSEYPWGDT
                     LLEGGYYHANTWQGRFPYENTALDRFIGTAPVYEFLPNDFGLYQMIGNVWEWCRNPRY
                     TLLASFNEDDYELPKYGIQDEEYAIRGGSFLCHCSYCNRYRVAARNGCISTSTSSHLG
                     FRCLKE"
     gene            complement(10249..11724)
                     /locus_tag="VQ540_000715"
     CDS             complement(10249..11724)
                     /locus_tag="VQ540_000715"
                     /EC_number="3.1.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arylsulfatase"
                     /protein_id="HET2544550.1"
                     /translation="MVQTKQPNIILIVVDQMRADALSLNSKDKLVSTPTLDMMASVGY
                     NFENAYSPVPSCVPARAALLTGLDQDKSGRVGYQDEVPWNFTNTLPKVFKDMGYQTEC
                     IGKMHVFPSRQRLGFDHVLLHDGYLHVDRKYDKAYGSQFDYVSDYLAFLKGKVGYDVD
                     LIDDGMDCNSWEARPWDKDEKLHPTNWVVSESISFLQRRDPTVPFFLKMSFEKPHAPL
                     NPPKYYFDMYMERLPQFLDLHIGNWEVLEKQIPSIYALRGKLKEDDQRRMVAAYFGLI
                     THIDHQISRFLTSLKEFRHDKDTIIWFVSDHGDQLGEHYLFRKGYPYQGSIHIPSFIY
                     DPAGLIAGNRGTIKQLVKIQDIFPSLVDLAGGTTTDELDGRSVKNLLFGQYEGWRTEF
                     HGEHALGKDSSQYILTDQWKFIWFPVLNHYQLFDMKKDPHEMNDLYPSEKYQPIVRQM
                     KKKLVDFLRYREEGFVVDEELVPVELSKITPTLTKTGDSQS"
     gene            complement(12047..13402)
                     /locus_tag="VQ540_000716"
     CDS             complement(12047..13402)
                     /locus_tag="VQ540_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HET2544551.1"
                     /translation="MNTMLDKMQEKLSPIAMKVGNQKFLVALRDSFVGTMPVIMTGSI
                     ALLLNAFLVDLPQQFHLESITKTFQWLVDINNLVFKGSIPIVSLLFIYCLGVNIAKIY
                     KVDTVSAGLVSLASFVISIGSTVTKSFPLANVGDVKLDQILQGIDNLAFDGKNLMVTI
                     GNVIPGNHINARGYFTAMMIGFLASIIFCKVMKKNWVIKLPDSVPPAIAKPFTSIIPG
                     FMAMYIVAILTYVFHLLSNDLLIDWVYKVLQTPLLGLSQSFFAVILMIFLNKLFWFFG
                     LHGGNVLAPIMEGLFGVAMLANLDAFQKGEPIPYIWTSGSFGAFVWFGGLGLVLAILI
                     FSRNSHYRKVAKLGLAPVLFNIGEPVNYGLPVVLNPLLFIPFVLSPVFMATVAYWATS
                     WGLVSPVTQNVTWVMPPILYGFFSTAFDWRAIILSVVCLIISVLTYFPFVKMADKTEL
                     S"
     gene            complement(13412..13729)
                     /locus_tag="VQ540_000717"
     CDS             complement(13412..13729)
                     /locus_tag="VQ540_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HET2544552.1"
                     /translation="MDESNLESVMGLIMYGGEAKSNAMEAIQAAKKGDFSKANRRLAD
                     ANAALLQAHKAQTEMLTREAQGEETSISLLMVHAQDHLMTSLTFVDLAKEVVEVYERF
                     EKN"
     gene            complement(13746..14063)
                     /locus_tag="VQ540_000718"
     CDS             complement(13746..14063)
                     /locus_tag="VQ540_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001151647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET2544553.1"
                     /translation="MAKVTIMLACAAGMSTSLLVTKMQKAAEDKGLDAEIFAVPAPEA
                     EEIVATKEVNVLLLGPQVRYLLGDFQEKLKDRQIPVAVIPMTDYGMMNGSKVLDLAES
                     LLD"
     gene            complement(14076..15761)
                     /locus_tag="VQ540_000719"
     CDS             complement(14076..15761)
                     /locus_tag="VQ540_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000791288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 16 glycosylhydrolase"
                     /protein_id="HET2544554.1"
                     /translation="MKNKKLISSLFILFLLIFIHVKVFANENLIKNSNFEQGELFWNS
                     RNRGIINSNESYSNGHYSGMIPSTAINDNRADGYIGQVIDIEPNEDYLVSAFAKVDIS
                     GAEGYFTARWFDNNKQGEIVQNNIGEAVDQTVNTTEWKKYMFSFNSGKHDKVLIQLVK
                     WSEDDTTKKSNIFIDNVEMYQLSKGNSYKKIWRDDFDGEQLNKKYWGYELGSIRGWEQ
                     QHYVRSDENVFLRSGNLVLRATNRSKEDQYFNPRNNHRKVVYNSGSVRTHGKVEFLYG
                     KLEMRAKLPKGQGVFPAFWTLGSDFTLDGKINPVQGRGWPSTGEIDIMELVGERNSNG
                     SGNKTVYQTLHYGQSDNDDGKFAGRGTAFKLSSGNFNDSYHTFSIDWYKDYIVWMVDN
                     HIVRKVYYGSDNIAKKIFNRPQYVQLNLAMGGSWPGVVDNNLSGTEFVVDYVSYSRND
                     LQQHQAEEYYSQSPKINGAKDIVINRGDVPDLLKGITTNSGYELDYSIENEPMFNNFG
                     GNTSVDLLIRNKTEKEKISQMPPGVYNLHYTSRPKHLDYESKVDRKTVTLTIK"
     gene            complement(15766..16662)
                     /locus_tag="VQ540_000720"
     CDS             complement(15766..16662)
                     /locus_tag="VQ540_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HET2544555.1"
                     /translation="MKRLISANPSEILQMNAEELKQSILASEGRVVLSENVVTRETFV
                     GDITNSEIARAFGADMILLNCVDVFEPKIYALDSSGDDVIHRLHQLVACPIGVNLEPI
                     DPSAKMLEETQEIVAGRVASVETLNRIEELGFDFVCLTGNPGTGVSNREIIKAVQTAK
                     ENFSGLIIAGKMHGAGVNEPVAELSVAEQLLEAGADVILVPAVGTVPAFHDQELREVV
                     DLVHSKGGLVLSAIGTSQETSDTDTIKEIALRNKICGVDIQHIGDAGYGGLATVDNIY
                     ALSKAIRGVRHTVSRLARSVNR"
     gene            complement(16665..17927)
                     /locus_tag="VQ540_000721"
     CDS             complement(16665..17927)
                     /locus_tag="VQ540_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HET2544556.1"
                     /translation="MEKLLQEKLLPVAARLGNNKALVSIRDGITLTIPLLLIGSLLMV
                     IASFPIPGWEKYLGDIGVADYLWKGVDSSFGLLGLVASFGIAYFMARQYKVDGIPAGI
                     VSLSSFITVTPFITGEAGAGMPTAFMASKGLFVAMILGLINGYIYQWFINHNIQIKMP
                     DGVPPAVSKSFSAIIPGAVTIVGWLIVYATLDKLSLPNLHEIAQGALGGPLGLLGNNV
                     IGLLILIFLNSSFWFVGLHGGNVVNAVMKPLWLANLDANKVAYQTGETLPNIFTSVFM
                     DNFVFIGGGGATIGLVLALGYLAHKKKASKQLKTLAPITVIPGLFNINEPAMFGVPIV
                     LNILLLVPFILAPMFNLLVAWGAMASGLVPLTYTDPSWTMPPVISGLLATGSISGSLL
                     QIVLIVLDVLLYLPFVIAIEKRFKLLED"
     gene            18207..19385
                     /locus_tag="VQ540_000722"
     CDS             18207..19385
                     /locus_tag="VQ540_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HET2544557.1"
                     /translation="MTLSKKQLQLRAKILETVYTLGPISRIEIATKTGITPATTSSIT
                     NDLIKENILLELGEDEHDTSVGRKKILLDIQAKRFYYIGCELSEKHFTFALGDNLGNI
                     LKEEKEIVTKQLIQEKGNQLINQTLKQFLNNCSDYEIEAIGIALPGRYLDDYKITTNN
                     PLWQHIDLEMIQSHFDKPLFFSNNVNCMAIGKRLFSRQQNDPNFAYFHFARGMHCSYI
                     YDGNIYGKGNLMIGEIGHTVVSSEGEECSCGRKGCLQTFAGESWLIKKSKILYHQSPY
                     SLLPSLVKNADDIDIQVILTAYQLGDTGIITLIHQALLYLSQTILNISMMIDSQKIYL
                     HSPLLTNQHIIQKLYSEMNYKPKLLYNRLPEVIIEPYNDFTAAHSAIALCLYHTILHS
                     "
     gene            complement(19613..20059)
                     /locus_tag="VQ540_000723"
     CDS             complement(19613..20059)
                     /locus_tag="VQ540_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000155432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2544558.1"
                     /translation="MTIRFEEKVSIENAQFVCQWSNSLGKSFQEQWMGPRIPFLLPLQ
                     ALEGVFSIFDEQEFVGLIQKIRLEDSNLHIGRFFINPQKQEQDLGSQALRKFVSLAFE
                     NEDIDSISLNVFEANQRAQNLYQKEGFEIVQMVEAPVRKYSGLKLE"
     gene            20129..20788
                     /locus_tag="VQ540_000724"
     CDS             20129..20788
                     /locus_tag="VQ540_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000564993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HET2544559.1"
                     /translation="MIDFYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTPLR
                     PLDLIPILSQVFNRFRCRYCKVRYPVWYALFELGLGLLFLLYSWELLSLGQVVLITAG
                     LTLGIYDFHHQEYPLLVWMTFHLILIASSGWNLVMVSFLILGILAHFIDIRMGAGDFL
                     FLASCALVFSVTELLILIQFASATGILAFLLQKKKERLPFVPFLLLATCVIIFGKLLL
                     V"
     gene            complement(20840..21991)
                     /locus_tag="VQ540_000725"
     CDS             complement(20840..21991)
                     /locus_tag="VQ540_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000481741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HET2544560.1"
                     /translation="MFNGRVLKELRLLNGLSRAELAQRINLTEQAIWQFESNETKPKL
                     STKMHLANQFHVDLTYFEQEEESIRFDSSVIAFRNADLATRKTIDIQTMYLHKVDSLI
                     DYFESFVIIPNITIHDLSNVVSESYHKGESIEELALYAREKLGISKDNHDLLYKLERS
                     GIYIVERLINGQADAYSAWSKLGRPYIVLGTNKSSVRRNFDLAHELGHILLHKYKDMN
                     EDGDRLEQEANYFASCFLLPKEEFLVKFEERVGKRVSNPDSYILLKSDLNVSIQALEY
                     RAFKLGLLTPKQHSYFYRQIAQKGYKMIEPLDDQIFVKKPSKVKSILDVVLSNHLVSL
                     ATIMSKQSIRLQFISEIFSVEMKFFDQYQEDRRTDRFDNIIPLYKRNNL"
     gene            complement(22006..22737)
                     /locus_tag="VQ540_000726"
     CDS             complement(22006..22737)
                     /locus_tag="VQ540_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000934015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2544561.1"
                     /translation="MLNQDLFDSLEAQKIVDTLMKGQKDYVDERLEKRETMIVSNGYA
                     WTRPNHIDTAFASADLFEYKLQLAGQTWGYLEFETNTEKYGKVLLIIKGKKRLTNQFP
                     LVQKNKSGYLFEYAQMNTLYLNQHSSYKNDEDSHSFPIQMELVSDEMIQEIEQATKNS
                     NIEKFMILTYEADSENNIISVDVVMPDARTGQLHLIQDLSEYIQSSSYHFEEAKYQDI
                     PNFSELSETEDFEIIPRIEKQEGQK"
     gene            22966..23067
                     /locus_tag="VQ540_000727"
                     /pseudo
     CDS             22966..23067
                     /locus_tag="VQ540_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234126.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
     gene            complement(23039..23815)
                     /locus_tag="VQ540_000728"
     CDS             complement(23039..23815)
                     /locus_tag="VQ540_000728"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit alpha"
                     /protein_id="HET2544562.1"
                     /translation="MPKTLTKKLNAIKAAGKGIFVPYIMAGDHEKGLDGLAETIHFLE
                     DLGVSAIEVGIPFSDPVADGPVIEEAGLRSLAHGTSTQALVETLKTIETEIPLVIMTY
                     FNPLFQYGVENFVKDLADTAVKGLIIPDLPHEHANFVEPFLADTDIALIPLVSLTTGI
                     ERQKELIEGAEGFVYAVAINGVTGKSGNYRADLDKHLAQLHQVADIPVLTGFGVSSQA
                     DLERFNAVSDGVIVGSKIVKALHQGEPIQDFIKQAVAYQK"
     gene            complement(23808..25031)
                     /gene="trpB"
                     /locus_tag="VQ540_000729"
     CDS             complement(23808..25031)
                     /gene="trpB"
                     /locus_tag="VQ540_000729"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit beta"
                     /protein_id="HET2544563.1"
                     /translation="MAYQEPNKDGFYGKFGGRFVPETLMTAVLELEKAYRESQADPSF
                     QEELNQLLRQYVGRETPLYYAKNLTQHIGGAKIYLKREDLNHTGAHKINNALGQVWLA
                     KRMGKKKIIAETGAGQHGVATATAAALFNMECTIYMGEEDVKRQALNVFRMELLGAKV
                     EAVTDGSRVLKDAVNAALRSWVANIDDTHYILGSALGPHPFPEIVRDFQSVIGREAKQ
                     QYRDLTGQNLPDALVACVGGGSNAIGLFHPFVEDESVAMYGAEAAGFGVDTEHHAATL
                     TKGRPGVLHGSLMDVLQDAHGQILEAFSISAGLDYPGIGPEHSHYHDIKRASYVPVTD
                     EEALEGFQLLSRVEGIIPALESSHAIAFAVKLAKELGPEKSMIVCLSGRGDKDVVQVK
                     DRLEADAAKKGEAHA"
     gene            complement(25009..25608)
                     /locus_tag="VQ540_000730"
     CDS             complement(25009..25608)
                     /locus_tag="VQ540_000730"
                     /EC_number="5.3.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylanthranilate isomerase"
                     /protein_id="HET2544564.1"
                     /translation="MTKVKICGLSTKEAVETAVSAGADYIGFVFAPSKRQVTLEEAAE
                     LAKLIPADVKKVGVFVSPSRVELLEAIDKVGLDLVQVHGQVAADLFENLPCASIQAVQ
                     VDGNGHVPNSQADYLLFDAPVAGSGQSFDWGQLDTTGLAQPFFIAGGLNEDNVVKAIQ
                     HFTPYAVDVSSGVETDGQKDHEKIRRFIERVKHGISGTK"
     gene            complement(25595..26362)
                     /gene="trpC"
                     /locus_tag="VQ540_000731"
     CDS             complement(25595..26362)
                     /gene="trpC"
                     /locus_tag="VQ540_000731"
                     /EC_number="4.1.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011227478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="indole-3-glycerol phosphate synthase TrpC"
                     /protein_id="HET2544565.1"
                     /translation="MSQEFLARILEQKAREVEQMKLEQIQPLRQTYRLAEFLKNHQDC
                     LQVIAEVKKASPSLGDINLDVDIVQQAQTYEENGAVMISVLTDEVFFKGHLDYLREIS
                     SQVEIPTLNKDFIIDEKQIIRARNTGATVILLIVAALSEERLKELYDYATELGLEVLV
                     ETHNLAELEVAHRLGAEIIGVNNRNLTTFEVDLQTSVDLAPYFEEGRYYISESAIFTG
                     QDAERLAPYFNGILVGTALMQAENVAQRIKELQIDKG"
     gene            complement(26359..27363)
                     /gene="trpD"
                     /locus_tag="VQ540_000732"
     CDS             complement(26359..27363)
                     /gene="trpD"
                     /locus_tag="VQ540_000732"
                     /EC_number="2.4.2.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate phosphoribosyltransferase"
                     /protein_id="HET2544566.1"
                     /translation="MKEIIEKLAKFENLSGVEMTDVIERIVTGRVTEAQIASLLLALK
                     MKGETPEERTAIAQVMRGHAQHIPTEIHDAMDNCGTGGDKSFSFNISTTAAFVLAGGG
                     IHMAKHGNRSISSKSGSADVLEALGINLDLKPAELGKVFDKTGIVFLFAKNMHPAMKY
                     IMPARLELGIPTIMNLTGPLIHPMALETQLLGISRPELLESTAQVLKNMGRKRAIVVA
                     GPEGLDEAGLNGTTKIALLENGEISLSSFTPEDLGMEDYAMEDIRGGNAQENAEILLS
                     VLKNEASPFLETTVLNAGLGFYANGKIDSIKEGVALARQVIARGKALEKLRLLQEYQK
                     "
     gene            complement(27374..27940)
                     /locus_tag="VQ540_000733"
     CDS             complement(27374..27940)
                     /locus_tag="VQ540_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HET2544567.1"
                     /translation="MILLIDNYDSFTYNLAQYIGNFAEVQVLRNDDSKLYEEAEKADG
                     LVFSPGPGWPVDAGKMEDMICDFAGKKPILGICLGHQAIAEVFGGKLGLAPKVMHGKQ
                     SNINFEAPSVLYQGIEDGRAVMRYHSILIEEMPEDFEVTARSTDDQAIMGIQHKNLPI
                     YGFQYHPESIGTPDGLSSIRNFIEKVVK"
     gene            complement(27937..29298)
                     /gene="trpE"
                     /locus_tag="VQ540_000734"
     CDS             complement(27937..29298)
                     /gene="trpE"
                     /locus_tag="VQ540_000734"
                     /EC_number="4.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate synthase component I"
                     /protein_id="HET2544568.1"
                     /translation="MERIIHGDVLSPILAYMRLKGQHKVILESIPRDKETARFSILAY
                     NPVFEIKFENGVLYQNGQAIDRDPLDFLYEVTHKSQHHSDLPFGGGAIGFVGYDMISL
                     YEEIGQIPEDTIGTPDMHFFVYESYMVFDHKKEKIHVIEDALYSERSQEALEKSLNQV
                     LEELRIPAPNEFEDLDLSPLDFKPHIAPHKFEGMVETARDLIRNGDMFQCVLSQRFSA
                     EVTGNPFDFYRNLRVTNPSNYLYFYDFGDYQIIGASPESLVSVKNGIVTTNPIAGTRP
                     RGATDEEDKALATDLLSDEKETAEHRMLVDLGRNDIGRISETASVQVTKYMEVELFRY
                     VMHLTSVVKGRLLAELTAMDALKATLPAGTVSGAPKIRAMRRIYELETEKRSVYAGAI
                     GYLSATGDMDLAIAIRTMILKNQRAYVQAGAGIVYDSIAQNEYQETINKAKSMTRIGE
                     LRP"
     gene            complement(29799..29876)
                     /locus_tag="VQ540_000735"
                     /pseudo
     CDS             complement(29799..29876)
                     /locus_tag="VQ540_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(30481..31482)
                     /locus_tag="VQ540_000736"
     CDS             complement(30481..31482)
                     /locus_tag="VQ540_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000789954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HET2544569.1"
                     /translation="MKNINGKKVTIYDIARLSGFSPKTVSRVINGGVNVKEETYQAIQ
                     KVIEELSYIPNAYAKNLTKKEAINILISVKKIDSFPLIWFHTLLDKVLRTCKEFGVNA
                     IVEYFGEEDTISNSIISSTGSLVDGVIVFYESVDDIRIQYLKKNHMPFLVFGESQTSG
                     VVYVSNNNFQATYDMMKAVTEEKFKNMWLLMGGESHVNKDRERGVRSFLNDKNYFMDL
                     KVIYGLSTIDSVYSYAMQHLTTQNYPDIIFVSGDEKVQGLIRACYEKGILIPDDISII
                     GFDNIPISQYYTPALSTIAPNYVKLAKEMIEGVLAIIKGESVTSVEVSPKFVRRQSF"
     gene            complement(31590..31958)
                     /locus_tag="VQ540_000737"
     CDS             complement(31590..31958)
                     /locus_tag="VQ540_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2544570.1"
                     /translation="MKDYKINFDLGKIEYFDNNCLIQVYKFISFYDICEMVFAFHLPP
                     DELITNVIFKEKINSMLKCYIDRLLYVFINPTHFTEKVNLQFYGSFFSYEFICREVGN
                     ILKNKGVKCNLNFFEGEEYL"
     gene            complement(32054..32764)
                     /locus_tag="VQ540_000738"
     CDS             complement(32054..32764)
                     /locus_tag="VQ540_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000127555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HET2544571.1"
                     /translation="MTATSLGLSNIEIVVRIVLSVVIGSIIGLERGSKSQPAGIRTYS
                     IVCLAACLIMMTNEYVSYKFGTGDPTRLGAQVISGVGFLGAGTILITDKKKITGLTTA
                     AGIWASAGIGLAIGVGFYEGALLVAISVWGVISMFQPLKKYLQNRSKMIELYIVVKST
                     EAYNRVLVYCAENGIRMTDSRTAFGDVNSDRIEYFDVPDKKIASFITLELSGRFEHLR
                     LMEEIANIVGVIYVEEIS"
     gene            complement(32767..34458)
                     /locus_tag="VQ540_000739"
     CDS             complement(32767..34458)
                     /locus_tag="VQ540_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HET2544572.1"
                     /translation="MRHKLNLKDWLIRLGLIWFLVTFIIYPNFDLVVNVFVKGGEFSL
                     DAVHRVLKSQRALQSIMNSFKLAFSLIITVNVVGILCVLFTEYFDIKGAKILKLGYMT
                     SLIYGGVVLATGYKFVYGPYGLITKFLQNVIPSLDPNWFIGYGAVLFIMTFSGTANHT
                     LFLTNTIRSVDYHTIEAARNMGAKPFTVFRKVVLPTLIPTLFALTIMVFLSGLSAVAA
                     PMIVGGKEFQTINPMIITFAGMGNSRDLAALLAIILGIATTILLTIMNKIEKGGNYIS
                     ISKTKAPLKKQKIASKPWNIIAHIVAYGLFTVFMLPLIFIVLYSFTDPVAIQTGNLTL
                     SNFTLENYRLFFSNSAAFSPFLVSFIYSIIAATTATILAVVFARVVRKHKSRFDFLFE
                     YGALLPWLLPSTLLAVSLLFTFNQPQFLVLNQILVGSLVILLIAYIVVKIPFSYRMVR
                     AILFSVDDEMEDAARSMGASPFYTMMKVIIPFILPVVLSVIALNFNSLLTDFDLSVFL
                     YHPLAQPLGITIRSAGDETATSNAQALVFVYTIVLMIISGTVLYFTQRPGRKVRK"
     gene            complement(34470..35480)
                     /locus_tag="VQ540_000740"
     CDS             complement(34470..35480)
                     /locus_tag="VQ540_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2544573.1"
                     /translation="MIKFDNIQIKYGDFVAIDNLNLDIHEGEFFTFLGPSGCGKSTTL
                     RALVGFLDPSSGSIEVNGTDVTHLEPEKRGIGIVFQSYALFPTMTVFDNIAFGLKVKK
                     VAPDVIKAKVSAVAAKIKISDQQLQRNVSELSGGQQQRVALARALVLEPKILCLDEPL
                     SNLDAKLRVDLRKELKRLQKELGITTLYVTHDQEEALTLSDRIAVFNNGYIEQVGTPV
                     EIYHNSQTEFVCDFIGDINVLTDETVHEVLLKNTSVFLEDKKGYIRLEKVRFNRETEQ
                     DFILKGTIIDVEFSGVTIHYTIKVSESQILNVTSIDSQAAIRSVGESVELFITPSDVL
                     QF"
     gene            complement(35583..36650)
                     /locus_tag="VQ540_000741"
     CDS             complement(35583..36650)
                     /locus_tag="VQ540_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HET2544574.1"
                     /translation="MKKMKVWSTVLATGVALTTLAACSGGSNSTTASSSEEKADKSQE
                     LVIYSNSVSNGRGDWLTAKAKEAGFNIKMVDIAGAQLADRVIAEKNNAVADMVFGIGA
                     VDSNKIRDQKLLVQYKPKWLDKIDQSLSDKDNYYNPVIVQPLVLIGAPDVKEMPKDWT
                     ELGSKYKGKYSIYGLQGGTGRAILASILVRYLDEKGDLGVSEKGWEVAKEYFANAYTL
                     QKGESSVVKALDKESPIQYGMIWGSGALIGQKEQNVEFKVMTPEIGVPFVTEQTMVLS
                     TSKKQALAKEFIDWFGQSEIQVEYSKKFGSIPANKDALKELPEDTKKFVDQVKPQNID
                     WEAVGKHLDEWVEKAELEYVK"
     gene            complement(36675..37334)
                     /locus_tag="VQ540_000742"
     CDS             complement(36675..37334)
                     /locus_tag="VQ540_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000793810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1868 domain-containing protein"
                     /protein_id="HET2544575.1"
                     /translation="MKNLTKIKFKENGEFNHFPGNTVVANLYTKQDLMEVVDIIQSRY
                     RELPFIDKFTLTPRNSIHMTVIELLCHENRETEFWSSNLPLDTPLQEIHDYFAKQLEI
                     FPLLDEEIHMRITEMGKQNILVEPADEASAKRLEEIRTYVSEKAGVCFPNHDRYQFHI
                     SIGYLRIPLTEEEEEEFTKVRAELTEILLEKIPTITVNRIDYTVFEDMRQFVPYHEKF
                     K"
BASE COUNT        12046 a         7633 c         5730 g        12043 t
ORIGIN      
        1 gtacaccata gtaattgttg agtttaatgg gccaccttgc gtcataacca ttggttgtac
       61 aatcagctta aaagcagaaa ttaaagttgt taacaataca aacagggctg ttggttttag
      121 taggggcatc gtgatataac gaaactgagc ccattttgag aatccatcta attcagcagc
      181 ttcatagaca tcttgtggaa tattctgcat tcctcctaaa aataaaagca tctgataacc
      241 tgcaccctgc caagcagaaa caaaaacaat tgcatacata gcttgtttag gactagtcaa
      301 gaaaggttga gaagcaatac ctaccttatt taaaatagca tttaataagc cactatttgg
      361 atttaaaaga taaagccaaa gaatagaaat aactaccaag gacatgacaa ctggagcaaa
      421 aaaagccact ttaaaaaaca tatttccttt tcgcttttta ttgacaatca aagccattcc
      481 taaggccgct cccaattgaa ctggaataat ccaaacaaca aatttcaaag tattcaagaa
      541 gctctttaag aaaatcggat cttttgttaa tcgaataaaa ttttcaagtc caacaaattt
      601 tctttcatct ggtgtcaaca aataataatc tgtaaaagcg taataaatga ccattccaac
      661 tggaattact aaaaagatac ctaataaaat taaagctgga gctaaaaaac tataacctaa
      721 tatgttatcc tttatttttt cacgtctttt tgtatacaca acagtttctt tactcatatc
      781 catctccttt aatcatatat atcaaactag gctattaaca agaaagggga aggtagttcc
      841 aaacattttc cttccacctt cttttttaca gattatttga gtgactgatc aatagcagtt
      901 tgcatttctt ttgtacgagt atccaagact ttttgcacat ttggattttc ttcataatag
      961 ctaatatctt gcattgcttg ttgaaaagct cgagaaacct gaggatatgc tacgacaact
     1021 gggcgagcat gagctgtttt tgaattttgt tccatcaaga aacgcattgg ttcggatact
     1081 ttatctttga tattttcaat tgtagattta cgaattggaa ggaccgaatt ccccaagcta
     1141 ataatttcac ttgattctgt atttgtagca aatttaacaa attcagatgc ggcctctttt
     1201 ttatcagatt ttgtcgtcac agctaattgc caactacctg aaggggatac taattttttc
     1261 gtcttactag atactgggta aggaaggata ccaaaatcaa tatctttgta gtttgtattc
     1321 atgtcagcaa tcgtccaaga accactcaaa agcattggat actctcctgt ttcaaaacct
     1381 ttttcgactg gactaacagt tgtatagcct tcttttacaa gattttgaat gaattgaact
     1441 gcttctacac tctctttgga gttgaagtat ccttctgcct ttgttccatc ttcgtttacg
     1501 acagaaccat tatttgacca aatcaacggc atataagcat atggcaacat ttcatcgttt
     1561 gaattaatac gaaaatcaat tgctggtttg ttataatgat ctttcaattt tttagcaatc
     1621 gtattaaatt cgtcccatgt ccatggcttt tctagcgttg gaagctctga ttccgcaatt
     1681 ccagcctctt tgaacatttt tttattgtaa taaacaccaa cattcgattc agaaaatcca
     1741 aatgcataga atttcccatt ataagttccc tgttgtttaa tactgtccaa aacatcatcc
     1801 atattattat cttttagata atcatctagc ggagtaatta ctttagattt tgcataagct
     1861 gccgtatttg gtccatcaag ggtaataaca tctggaagac tattagtcgt aatagcagca
     1921 ttaaccttgt cttcatatcc tccaccacta ccactacgag gaatatactc agttacaacc
     1981 ttgtacttac tttttcctga ttgattaaag ttatcaacaa ctttttgcca agcttttcct
     2041 tcatttgttt cgtcagagaa ttgtacccag actttaatat catttgaaga actcgcttgt
     2101 tttgagttag ttcctccact acaacctgca agtatagcta acgatagccc cgcaacaaca
     2161 gataacattg tacctttacg catcattttt ctcctttttg aaacgtttca ttttttattt
     2221 attttttaaa caagcttcta gcctattttt gaaacgtttc atttgttgat tatattataa
     2281 cagcgctttc attaattgtc aagcgctttt taaatttttt ttgttgtttt atctccccca
     2341 aaatatgtgg gaattacgat tcgtttttct agaatctctt ctcgcttaat cattttcagt
     2401 atcattgcaa cagattcttt tgccatcata ccaatatctt gaactattgt agacactaga
     2461 taagattgat cgacagaagt ttttaaacca tcaaacccaa ttatctggta atcatcaggt
     2521 gctattttcc ccagttcttt cataacacta ataactctca gagccatcat atcatttatt
     2581 gtaaatatac catcaatttc tttatgagat tgcaaaaaaa ttcttatctg atcttcagga
     2641 tttattaaag gttctttcat ttcaaaatta tagacatcta ctcctaattc cttagctttt
     2701 tctctgaatc ctttacttct gagtatagtc tcattctcat acatattaat tgaaccaata
     2761 aaagcaaggt gcttattatc ccttctaacc agttcctctg ctgcagtttg tcctcctttg
     2821 taatttgctg aagtaacata gcatacattt tccgaaaaat gtctatctat acttacaaac
     2881 ggtaaatcag ataaaatata tttgtcaata tcagaatatg taataccaat aattccatcc
     2941 actttatttt gtttcaacat ttcgatatat tcgatttcat tttgtgaatc gctatcagcg
     3001 ttacaaataa ataatttata attatatttt aataactctt tctcaacatg ataggcaaac
     3061 tccgaaaaaa atggatgcca tatgctcgga ataatcaaag cgatagtttc tgttctattc
     3121 tttttcatac ctcgagcata attatcaggg atatagtcca atgtttttat agccctttga
     3181 actttcctta aagttacttc tttaatgcct ttttctttat taattacacg tgaaacagtt
     3241 ccaacactaa ctcctgcttc taaagcaaca tctttcatgg taattgattt tctttgttct
     3301 accatattat cacctccttt caatatatag tatcatgcaa atgcttttta agcaactatt
     3361 tctcaatcat ttttggccag atcatttatc ccatcatgaa taaaatcact ccaattagct
     3421 tttgaaaata cttcaatttt catgtgtaaa catctacata aaacaggaaa agccttggtt
     3481 ttatggcttt tttcgtatct tctacaaaaa aagcaagagt tttagagggc tataaatcta
     3541 gatgtacatt ttgcttaaat gattgaaggt cttttcttaa caaaaacacc ccaaaaatta
     3601 gattttttct gtctaacttt tgaggtacag ttcaaacgcg aaatagcgtt tttttgttat
     3661 ttttggttac tcatctaatc gaataaacat catggcattt aacaaatata tgagtgagac
     3721 cgtgtttata ttatttgaat agatgagtct cttattttca ataggaggaa taataaaatt
     3781 agaaataatg atatcataag atgaatcttc taaagattcc tttgataatt ctaattcagt
     3841 ccaaacttcc agttcaaaat tattgctaca gtaataagaa agtgtctctg caacgaattt
     3901 tgcatgatac tgatcaaaat tactcataac caaaaccttt agtttaggct gattttgtag
     3961 caaattaatc accaaatgtt tggtatgagt gatgaaggta taagatagat gatttaccat
     4021 cattgaacta gaacaaacct caagagtctc taaatagtga gaaagctctt tttttatatc
     4081 tgaaacaaat tttggaaaaa tattttgaaa gttcctgatt gtattccctt tttgatcaaa
     4141 taaaataaac tcagtaaaca actcttgacg atacagatgt gcggtattat gcagatgcca
     4201 aatcagatta tccttattct ccatttcaat ctgatacttg actgaaatct gatcaataaa
     4261 atcactcaat agatggtaag atttttcaac ataactatcc ttttttacgc atttcataaa
     4321 gagactttca tctatgaaaa acattttttg aaagtaagac acaaataatt ggcaaacaac
     4381 ttcttcatct aaagagatat tgtattctga ttcaaaactc tgagcaacac cttctattcc
     4441 ttctgcctgc attaaaaaat ccaaactttg gtcgttaaaa gaatctttat ctacttccat
     4501 aaaatgacca aactttattc tatataggtt cgtaactagg agcaacttta gcattctatg
     4561 cgttgacaaa ttcattggaa agcttgtttc cttataaacc aattctaaca attgagatag
     4621 tggctctgat gaaaaatttt caaatggcca ttctaggaaa taatattttt ctgaaaaata
     4681 ttgtgcaaaa aagtaacgaa tgtctctctc atttccaatg atttgaacag gggtcagact
     4741 gacttcaaat tgaaattgcc ttttaatcac tttattgatt tggctaataa tacgatagag
     4801 cgaagatgaa ctgatataaa attctttaca aatactctca gcttgacaac cttcattaaa
     4861 gaagatgaat tctaaaatcg aaaaatgagt tgaatgttta aagaaatgat ggtaaaccat
     4921 ttcaatatca ctatcatcgg tattaataat gcgtatacca ttagtagaag aatgaaaaat
     4981 caagtcagga aaagcagatt taacatggga tagatcatct ttgactgcac gttctgtaca
     5041 atttaataac tctgctagtt cagaacgatg aaaccaacgt ttatgttcaa ataataattc
     5101 taataattct aattgcctat gacttttttt agataataaa tctctcatga atatctttct
     5161 ctctttataa attatcggat taaacctctt gcaattatac cacaaagaat aggtatagca
     5221 tgatataacg acttttccta aaatctttta tttcgtataa taacactacg gagacaatat
     5281 ataaacaatt ttcttatttt accgtctatt gagggcgtga atacagaatc aaattcaagt
     5341 ctaaagatta tatttttaat tttaaaaatt atataatagc aacaattaaa gaatttgatt
     5401 ttttaaaatt atataataat aacaatcgaa ataattgact tttctatatt aaagttatat
     5461 aatagtatta atcaaagaaa ttgatttttt gatattaaaa taaaaaagga gggtaggcag
     5521 tgttgtgatc aattattgct ggaggtctta ttggtctctt ggcaggtaaa atcactaaaa
     5581 aagtagttct atgggaatca tcgcaaatgt attcgctggt ttagtcgggg catatgcagg
     5641 acaatctctt ttaggtagtt ggggtccatc aatcgctgga atggctttgc tcccatctat
     5701 tgtaggtgca gcgattgtga ttactgtagt gtcattcttt acaggtagaa agtaaacttt
     5761 tcgccagtaa agttagcaaa ctatttttaa atcaatgacg ggaaaaatag tttaaatgtt
     5821 aaatcgaaag gattgtatat gtcaaaagca aagaaaatat gtttcattat tttctgtatt
     5881 ttaatcttga caattttcct tcctgttttg atagattatc atcaagttag tgatctaggt
     5941 attcatctac ttagctggag acagaactcc gtagttgaat tctatcttgc tagatatgtc
     6001 ttttggggga cagtggttct atcaacttta gttttattat ccattttagt tgtgatgttt
     6061 tatcctaaac gttacttgga aatccaactt gaaactaaaa acgatacatt aaaattaaag
     6121 aattcggcaa tcgaaggttt tgttagaagt ttggtgagtg atcatagatt gatcaagaac
     6181 ccaactgttc atgtaaattt acgaaaaaat aaatgtttcg ttcatgtaga aggtaaaatt
     6241 cttccttcag acaacatcgc tgacagatgc caaataattc aaaatgaaat aactaatgga
     6301 ttgaagcagt tttttggtat tgagcgtcaa gtaaaacttg aagttgcagt aaaaaattac
     6361 caaccaaaac ctcaaaacaa aaagactgtt agtcgtgtga agtaaggaag taaaaaatgg
     6421 aatggcttaa acaatatcga tatccaatta tcgctggtct cataggcgta tttctggctt
     6481 gtttgattgt ctcctttggc ttcttcaaaa caatatttgt attgatttta ggagcactgg
     6541 gagttgcagc tggattatat atcgaaaaaa actatataga taaataaaaa aataaaaatt
     6601 actaatttaa ttaaaggagt ttcatatgtc aaacgaaaaa aacacaaata ctaacgtaga
     6661 aaagaaagat gctactgttg tagctcacga aatcaaaggg gaacttactt acgaagataa
     6721 agttatccaa aaaatcattg gtctttcact agaaaacgtt tcaggtcttt tgggaatcga
     6781 tggtggtttc ttctcaaatc ttaaagaaaa aatcgttaac agcgatgacg taacaagtgg
     6841 tgttaacgta gaagttggta aaacacaagt tgcagttgac ttaaacgtta ttgttgagta
     6901 ccaaaaaaat gttccagctt tatattcaga aatcagagaa atcgtatctt cagaagttgc
     6961 taaaatgact gacttggaaa ttgttgaaat caacgtaaac gttgtcgaca tcaaaactaa
     7021 agaacagcat gaagcagact cagtaagcct tcaagatcgc gtatctgacg ttgctgaatc
     7081 aacaggagaa ttcacttcag aacaattcga aaaagctaaa tctggtcttg gatctggttt
     7141 ctcaactgtt caagaaaaag ttagcgaagg tgtagaagct gttaaaggtg cagcaaatgg
     7201 tgtagtatct cacgaaaaca ctcgtgtaaa ctaagataaa ataaatataa caggagaaat
     7261 tatcatgtca gtagaagaaa aattaaatca agctaaaggt tctattaaag aaggtgttgg
     7321 gaaagccatc ggtgatgaaa aaatggaaaa agaaggagca gctgaaaaag ttgtttctaa
     7381 agtaaaagaa gttgccgaag acgctaaaga cgctgtagaa ggtgctgtag aaggtgttaa
     7441 aaacatgttg agtggcgatg ataaataagg ttaaaagtta ctttatcttt ttggtaacat
     7501 tagtcaaaag agtctgagtc aagatgattc tcagaaaaca aaaagctaga gattcccaat
     7561 tgcggaactc tagcttttta attttgcctc tttctcttat tatatttcag caggttgttg
     7621 gccatgagta tgaatcccat gtcaattctc acttgacgct tacctctcag atgacatctc
     7681 ttataaccca aacaaacctt tatctgccca aagacagatt tcatatcaat cttacgttta
     7741 gcgaaaattt gtctaccctt ggaagataaa agtgcctgat attctttagt ttttaaacac
     7801 tggtaacgtt cattcatata cagtcccttt tgaggggctg attcaggttc ataatcgcag
     7861 tcaacattga tttcaaggct gtttgctttc tatctcccct ttttcatgat atattttcgt
     7921 acaggttctt caatagtttc tatagtaaaa tgaaccaaaa atagtacacg ttgcggtata
     7981 atgttcttgt ggcatattca ttagattttc gtaaacagtt ctctcctatt tgtgagcgaa
     8041 caagtatagt caattgattg tcagtttgaa gaccaagagt cgtaaggcaa aggatatggc
     8101 agaatccatc caagggtggc tggcacaatt tctagtgaac ctctttaaat ctattacgtt
     8161 tgactgtgga aaagagtttt caaaatggaa agatatttcc aatcatcacg atagtgagag
     8221 cttttttgcg aatctaggat gttcaagaca gcggcgtctc aacgaacatt caaatagact
     8281 tttaaggtgt catgacttgc caaagcagac agatttcaac gaagtcagtc aagaatttta
     8341 ggctggacaa aaactcaatt tcaggagaaa atgaaataaa tattcccaca ataaaacgca
     8401 tagtatcaaa gtttttccaa cacctgatat tatgcatttt ttaattttaa agactttttc
     8461 ccagcctcaa gaaatcacat cccacctaaa tcctttggat accaaatacc tcatcaggta
     8521 ttttctgagt tggtaagaat gtctagctta atttgacaaa tggagggcgt taaatccagt
     8581 ttttacagga agtctattta aatattttca cactgacctt acaaaatatg aaataaatta
     8641 tataaagtca ttcccatgac aaagaataac atccctttaa aacagtatct tacccaattt
     8701 tcaggtaaga cttttgatac aaccgtcccc aatacccctc cgcatataga agcaagaaaa
     8761 ataactggaa caggtgctaa atgatactga tttaaacctg taaccacaac aattgtagcc
     8821 aaatgagaca gctgggaaaa gaaaataatt gcaagagaat acatcgttgc ttcttttatc
     8881 gaaatagaaa aaaacaccat caataaagat acattgagcg gaccaccacc aatccctaaa
     8941 aaactagaaa ttaagcccaa tagaagacca caaatcatat agaatcctat cttatcaaat
     9001 tgataagttt ttttaaaatc tgttaaaaca aatgatacaa gtagcatcac aaatagtaaa
     9061 atcatttgaa caatggatac tagccgtact gataactgag ataacaaaac ttgaaaaata
     9121 agatgaccta gaaatcctcc taaaacagaa gaaaaggata ccgtaaaaat caatctccat
     9181 tttatctctt tactttgtga aaatcttttg attgttgaaa taatcgccat tataaaaaca
     9241 gagaaactag aataaaaagc aatatcactg accgaatggt atccaaaact atccataagt
     9301 ggcttaatta taattccacc acccatgcct gatatagaac ccaatccact agctattata
     9361 atgattagaa aataaataat ctcaaccact ttttaagtcc atcctattct ttcaaacatc
     9421 taaaacctag atggctacta gtggaagtag agatacatcc atttctagca gctactcggt
     9481 atcgattaca ataagaacaa tgacataaaa aggaacctcc tctgatagca tactcctcat
     9541 cttgtatccc atattttggc aactcatagt catcttcatt aaaactagct aataaggtat
     9601 atctcggatt gcgacaccat tcccaaacat tcccaatcat ttgatataga ccaaaatcat
     9661 taggtaaaaa ttcatagaca ggagccgttc ctataaatct atctaaggca gtattttcat
     9721 aaggaaatct tccttgccaa gtattggcat gataatatcc accttctaaa agagtatctc
     9781 cccaaggata ttcagattgt cttcctcctc tagcagcata ttcccactgt gcttcagtag
     9841 gtaaagacat tccgctccaa ttacagaaag ccaatgcatc ttctaaagca acatgaacta
     9901 ctggatggtc ttctaaaccc actagattac tgttctcacc gtagggatgt ttccagcaag
     9961 cgttcggaac ttgtaaccac cacggagccc cagcaggatg aggatatccc tccctttctg
    10021 cctctggaac gaacaatata aaaacaaaag accactcttg tcgctcagct agtgttttat
    10081 agcctgtttc tttcacaaat tgagcaaatt cttgattcgt aactggagta tccgcaatgg
    10141 aaaaatcctt tacactaaca gcgacttgag gaccttcaaa atcatctaaa aagccctctt
    10201 cagaatttgt tcccatcata aatgtcccac ccttgatttt tttcattttc atgattgact
    10261 atcccccgtt ttcgttagag ttggcgttat tttagaaagt tcaacaggaa ctaactcttc
    10321 atccacaaca aaaccttctt ctctatatct aagaaagtct actaattttt tcttcatctg
    10381 acgaacaata ggttggtatt tttcgcttgg atacaaatca ttcatttcat gcggatcttt
    10441 tttcatatca aataactgat aatgatttaa aacaggaaac cagataaatt tccactggtc
    10501 tgtcaagata tattgactag aatcttttcc taaagcatgt tcaccatgaa attctgttcg
    10561 ccacccctcg tactgtccaa ataataaatt cttaacactc cgtccatcta gttcatctgt
    10621 agtagttcct cctgccaaat ccacgagtga aggaaaaata tcttgaattt tcactaattg
    10681 cttgattgtt cccctattac cagctatcaa tccagccgga tcgtaaataa acgaaggaat
    10741 gtggatactt ccctgataag gatatccctt tctaaacaga taatgttcac caagctgatc
    10801 tccatgatcc gaaacaaacc agataatcgt atctttatca tgacgaaatt cttttaggga
    10861 agtcaaaaag cgactaattt gatggtctat atgagtaatc aatccaaaat aagcagcaac
    10921 cattcttctt tgatcatctt cctttaattt ccctcttaaa gcataaatag acggaatttg
    10981 cttttctaat acttcccaat tcccgatatg caaatcgaga aattgaggca agcgttccat
    11041 atacatatca aaatagtatt ttgggggatt taatggagca tgtggttttt caaaagacat
    11101 tttgagaaaa aaaggaaccg ttggatctct tctttgtaaa aatgaaatgg actcactcac
    11161 aacccagttt gttggatgta acttctcatc tttatcccaa ggtctagctt cccaagaatt
    11221 acaatccatt ccgtcatcaa tcaaatcaac atcataacca actttaccct ttaaaaaggc
    11281 tagatagtca ctaacataat caaattgact tccataagcc ttatcatact ttctatcaac
    11341 atgtagatac ccatcgtgaa gtaagacatg atcaaaccca agtctctgtc tggaaggaaa
    11401 aacatgcatc ttaccaatac actctgtttg ataacccata tctttaaaga cttttggaag
    11461 agtattagta aaattccaag gcacctcatc ttgataacca acacgtccac ttttatcttg
    11521 gtctaagcca gtcaataaag ctgccctagc aggaacgcaa gaaggaactg gagaataggc
    11581 attttcaaaa ttataaccta cactagccat catatctaat gttggagtgc taactagctt
    11641 atccttacta ttcaaggata aggcgtctgc tctcatttga tctacaacaa tcaaaataat
    11701 atttggctgt tttgtctgaa ccataaaatc tcctttctaa tatggcaaaa gaggcacaag
    11761 aagatatcta cctttactgc acccctttct atatcaatct ctctatataa agcaataaca
    11821 ttcttgttat gttttataga acaatgaact aaaatatgac taaatcgatt aggaaattca
    11881 aatcattttc tagtactgtt ttagaagtta cagtgtacta ttccaacttc aacaaactat
    11941 aaaccttggt ctaataacaa ttttagtgga gataagaaat cctacaccta actcatctta
    12001 cacgtaatct atttctattt tatcacaaaa aacgcaagta agaccattaa ctcaattcag
    12061 ttttatctgc cattttcaca aatgggaaat aagtcaagac actaataatc aaacaaacaa
    12121 ctgataagat gatggcacgc caatcaaatg ctgtagagaa gaaaccatat aaaattggag
    12181 gcattaccca agtaacattt tgtgtaacag gtgaaacaag accccagctt gttgcccagt
    12241 aagctaccgt tgccatgaaa accgggctaa gtacaaatgg tataaatagc aaaggattca
    12301 agacaactgg taaaccataa ttgaccggct caccaatatt aaacagaact ggtgctagac
    12361 caagtttagc aacttttcga taatgactgt ttcttgaaaa aattaaaata gcaagtacca
    12421 atcctaatcc tccaaaccag acaaacgccc caaaagaccc acttgtccat atataaggaa
    12481 tcggttcacc tttttggaaa gcatccagat tcgctaacat agcaactcca aacagccctt
    12541 ccatgatggg agccaataca tttcctccat ggagaccaaa aaaccagaat aacttattta
    12601 aaaagatcat cagaataact gcaaagaaac tttgagacaa acctagtaat ggcgtttgta
    12661 acaccttgta aacccaatca atcaataagt cattgctaag taaatggaaa acataagtca
    12721 agatggctac tatatacatc gccataaatc ctggaatgat agaagtgaac ggcttagcaa
    12781 tcgcaggggg aactgaatct ggtaacttga ttacccagtt ctttttcatt actttacaga
    12841 aaataataga ggctaaaaat ccaatcatca tggctgtaaa gtagcctctg gcattaatat
    12901 ggtttcctgg aatcacattc ccaatagtta ccatcagatt tttaccatca aatgctagat
    12961 tatcaattcc ttgtaagatc tgatctaatt tcacatctcc tacatttgcc aaagggaaac
    13021 tctttgtaac tgtacttcca atcgaaatga caaacgaagc aagtgatacc aaaccagcag
    13081 aaactgtatc aaccttgtaa atcttagcga tattcactcc caagcaatag atgaacaaca
    13141 aagaaacaat tggtatactt cccttgaata ccaaattatt gatgtcaaca agccactgaa
    13201 aggttttcgt aatactttct aggtgaaatt gttgtggtaa atccactaga aaagcattta
    13261 ataacaaagc aatggaacct gtcataataa caggcatagt ccccacaaat gaatcacgta
    13321 aagcaactaa aaacttctga ttcccaactt tcattgcaat tggagaaagt ttttcttgca
    13381 ttttatccaa cattgtattc atactaaact cctaattttt ttcaaatcgt tcgtatactt
    13441 ctaccacttc tttcgccaag tcaacaaaag tcagactcgt cattaaatga tcttgcgcgt
    13501 gtaccatcaa gaggctaatt gatgtttctt ccccctgtgc ctctcttgtc aacatttctg
    13561 tttgagcctt atgcgcctgt aataaggcag cattcgcatc agctaatctt cgattggctt
    13621 tagagaaatc cccttttttt gctgcctgaa tagcctccat agcattactt ttggcttccc
    13681 caccatacat aattagcccc attacagatt ctaaattact ttcatccata acattctcct
    13741 caatcttagt ctaataaact ttcagctaaa tctaaaactt tagaaccatt catcattccg
    13801 taatctgtca tcggaataac cgccacagga atctgtctat cttttagttt ttcttgaaag
    13861 tcccctagta aatagcgaac ttgggggcct aaaagcaaca catttacttc ttttgttgct
    13921 acaatttctt ctgcttcagg agctggaact gcaaaaattt ctgcatccaa ccccttatct
    13981 tctgctgcct tttgcatctt tgtcactagc agacttgtac tcatacctgc tgcacacgct
    14041 aacataattg ttactttagc catagcttac tccttttatt ttattgtcaa tgttactgtt
    14101 tttcgatcaa ctttagactc ataatctaaa tgtttgggac gactagtata atgcaaatta
    14161 taaactcctg gaggcatttg tgaaatcttt tctttttcag ttttattgcg aattaataaa
    14221 tctaccgaag tattccctcc aaagttatta aacataggtt cattttcaat agaataatct
    14281 aactcatatc cactattagt tgtaattcct tttaataaat caggaacatc tcctctgttt
    14341 attactatat ccttagcgcc atttattttg ggagattgac tataatactc ttcagcttga
    14401 tgttgttgta aatcatttct agagtaagaa acataatcaa ctacaaattc agtccctgat
    14461 aaattattgt ccactacccc aggccaactt cctcccatcg ctaaatttaa ctgaacatac
    14521 tgaggtctat taaaaatctt tttcgctata ttatctgatc cataatatac ttttctaaca
    14581 atatgattgt caaccatcca tacaatataa tctttatacc aatcaattga aaaagtatga
    14641 tacgaatcat taaagtttcc actcgataat ttaaaggctg taccacgtcc tgcaaatttt
    14701 ccatcatcat tatccgactg tccataatga agcgtttgat aaactgtctt attcccactt
    14761 ccatttgaat ttcgttcacc aactaattcc attatatcta tctcacctgt tgacggccat
    14821 cctcgtccct gaacaggatt aatcttccca tcaagtgtaa aatccgatcc aagagtccag
    14881 aaagcaggaa aaactccttg acctttcggt aattttgcac gcatctctaa tttaccataa
    14941 agaaattcta ctttcccatg tgttctaaca cttcctgaat tatatacaac ctttctgtga
    15001 ttgtttcttg ggttaaaata ctgatcttcc ttagagcgat tcgtagctct aagaactaaa
    15061 tttcccgaac gtagaaaaac attctcatca cttcttacat aatgttgctg ttcccaacca
    15121 cgaattgatc ctaattcata tccccaatat tttttattta attgttcgcc atcaaaatca
    15181 tctctccaaa ttttcttata tgaatttcct ttagacagtt gatacatctc tacattatca
    15241 ataaaaatat tagatttttt tgtagtatcg tcttctgacc atttcactaa ttgaatcaaa
    15301 actttatcgt gtttaccgga attgaaagaa aacatgtatt ttttccattc ggttgtatta
    15361 actgtttgat caacagcttc tccaatgtta ttttgaacaa tctctccttg cttattatta
    15421 tcaaaccatc ttgcggtaaa atatccctct gctccactaa tatctacttt ggcaaaagca
    15481 gatactaaat aatcttcatt aggttctata tcaataactt gtccaatata tccatctgct
    15541 ctattatcat taattgcagt agaaggaatc atacctgagt aatgtccgtt actataactc
    15601 tcatttgaat taattattcc cctatttcta gagttccaaa acagctctcc ttgctcaaaa
    15661 tttgaatttt ttattaaatt ttcattagca aaaactttca catgaataaa tattaataaa
    15721 aataatataa ataaacttga aattaatttc ttattcttca ttttatcacc tatttactga
    15781 cctagccaag cgagatactg tatgtctcac tcctctaatt gccttgctca atgcataaat
    15841 attatcgact gttgccagtc ccccatatcc tgcgtcacct atatgttgaa tatcaactcc
    15901 acaaatttta tttctaagtg caatttcctt gatagtatct gtatcagatg tttcttggct
    15961 agtaccaata gcactcagta ctagcccacc cttactatga acgagatcaa cgacttcacg
    16021 caactcttgg tcatgaaagg ctggaacggt tccaactgct ggaacaagta tcacatccgc
    16081 acctgcttcc aacaattgct ctgcgacaga aagctctgcc acaggctcat tcactcctgc
    16141 cccgtgcatc ttacctgcaa taatcaaacc agaaaagttt tccttagcag tttgaacagc
    16201 cttaatgatt tctcgattgc taactcctgt tccaggattt ccagtcaaac agacaaagtc
    16261 aaaacctaac tcctctattc gattcaatgt ttcaacacta gcaacacgac ctgcaacaat
    16321 ttcctgtgtt tcctctagca tctttgcaga tgggtcaatc ggttccaaat ttacaccaat
    16381 tggacaagca acaagctggt gtaagcgatg aataacatca tcacctgaac tatccaaagc
    16441 ataaatttta ggctcaaaaa catcaacaca attcaataaa atcatatcag ctccaaaagc
    16501 tctagcaatt tcagaattag ttatatcccc aacaaatgtc tcacgagtaa ctacattttc
    16561 agatagaaca actctacctt cacttgctaa aatactttgt tttaattctt cagcattcat
    16621 ctgtaatatc tcagatggat ttgcactaat taaacgtttc attctcaatc ctccaataac
    16681 ttaaaccgtt tttcaatagc tattacaaat ggtaaataaa gtaagacatc caaaacaatc
    16741 aatacaattt gtaataatga accagaaata cttcctgtag caagtaaacc acttataaca
    16801 ggtggcatag tccaacttgg atctgtataa gttagcggaa ccaaacctga tgccattgct
    16861 ccccacgcta ctagtaagtt aaacattgga gctaagataa atggaactag taacaaaatg
    16921 ttcaaaacaa taggaacgcc aaacattgct ggttcattta tattaaataa tccaggtata
    16981 acagttatag gtgccaaagt ttttagttgt ttactagctt tcttcttatg tgctaaatat
    17041 cctaacgcaa gaactaaacc tatggttgca ccaccgccac ctatgaatac aaaattatcc
    17101 ataaatacgc tagtaaaaat atttggaaga gtttctccag tttgataagc tactttattt
    17161 gcatctagat tagctaacca taacggtttc ataactgcat taacaacatt tcctccgtgt
    17221 aatcctacaa accaaaaact actattaagg aaaattaaga taagaagacc aataacatta
    17281 tttcctaaaa gtccaagtgg acctcccaaa gctccttgag caatttcatg aagattaggt
    17341 aaacttaatt tatctaaagt tgcataaaca atcaaccaac caacaatagt cactgcacca
    17401 ggaataatgg cactaaagct tttagatact gctggtggaa caccatccgg catttttatc
    17461 tgtatattat gatttataaa ccattggtag atatagccat taatcaatcc taaaatcata
    17521 gcaacaaata aaccttttga tgccatgaaa gcggtaggca ttcctgctcc agcctctcct
    17581 gtaatgaaag gcgtaactgt aataaaagat gataatgaca caataccagc aggaatacca
    17641 tcaactttgt attgtctagc cataaagtaa gcgataccaa aactagctac aagaccaagt
    17701 aatccaaaac tactatcaac acccttccat aaatagtcag caacaccaat atcacctaga
    17761 tatttttccc atcctggaat aggaaaactt gcaataacca ttagtaatga acctatcaac
    17821 aataaaggta tagttagagt aataccgtct cgaatagaaa ccaacgcttt attattaccc
    17881 aatctagccg ctactggaag taacttttct tgtaataatt tttccataac cttttcctct
    17941 taaatatatt ttattatcaa aagttatcaa ttatctttat tttttgacgt caagttatta
    18001 tttgattatc ttttgttatt tatattttac aactataaga aagccttgtc aaggatttgt
    18061 gtaaatattt gattattttt tattatcaat atataataaa aagagaccag taagcaatga
    18121 aaagcttaaa aagattaaca tctacattta tccatagcaa aaaatcatag gattttaaga
    18181 atctgacaac taggaagaaa actaatatga ccttatctaa gaaacaatta caactaagag
    18241 ctaaaatact ggaaacagtt tacacattag gtcccatttc acgaattgaa atcgctacta
    18301 aaacaggaat aacacctgca acaactagca gtatcacaaa tgatctgatt aaagaaaata
    18361 ttctcttaga acttggtgaa gacgaacacg atacaagcgt agggagaaaa aaaatcctgc
    18421 tagacattca agctaaacga ttttactaca ttggttgtga actatctgaa aaacatttca
    18481 cttttgcttt aggagataat ctaggaaata tcttaaagga agagaaagaa attgttacta
    18541 aacagttaat ccaagaaaag ggaaatcaac tcattaacca gacactaaag caattcttaa
    18601 ataactgctc tgattatgaa atagaagcaa ttggaatcgc gctacctggt cgctatttag
    18661 atgattataa aataacaaca aacaatcctt tatggcaaca tatcgactta gaaatgattc
    18721 aatcccactt tgataagcct ttgtttttct ctaacaatgt taactgtatg gctataggta
    18781 aacgcctatt tagtcgccaa cagaatgacc ctaattttgc ttattttcat tttgctagag
    18841 gtatgcactg ttcttatatc tacgacggaa acatttatgg gaaaggaaat ctaatgattg
    18901 gagaaatagg gcatacagtt gtttcatctg agggagaaga atgtagctgc gggcgcaagg
    18961 gatgcttaca aacttttgct ggagaatctt ggttaatcaa aaaatcaaaa attctatatc
    19021 atcaatctcc ctattctcta cttcctagtt tagtcaaaaa tgccgatgat attgatatcc
    19081 aagttatttt aaccgcttat caattaggtg acactggaat aatcacactt atccatcaag
    19141 ccttactcta tcttagtcaa accattttaa atatcagtat gatgattgac tctcaaaaaa
    19201 tctacctaca tagtccttta ctaacaaatc aacacatcat ccaaaaacta tatagtgaaa
    19261 tgaactacaa acccaaactg ctctataatc gcctacctga agtcattatt gaaccttaca
    19321 atgattttac agccgcacac tcagctattg cactttgttt gtatcataca attctacatt
    19381 cttaattttc tattacattt aataaatagg ctaaaaagag ggagtatatc ataaaaagcg
    19441 aataaacctg ttttctgaaa atcagaattc tgttttgttc gctttcttta tatttggaat
    19501 tatactccta tctccccttt ttcataatgt atagtgaaat gaaataataa caggacgaat
    19561 cgatcgggac agtcaaatcg atttctaaca atgttttaga aatagaggtg tactattcta
    19621 gtttcaatcc actatatttt cgtacaggtg cttcaaccat ttgaacgatt tcaaatcctt
    19681 ctttttggta aagattctga gctctttgat ttgcctcgaa gacatttaga gaaatactat
    19741 ctatatcttc attttcaaag gccaaactaa caaatttcct taaagcctgg ctacctaagt
    19801 cttgctcctg tttctggggg ttgataaaaa atctcccgat atgaagattg ctgtcttcta
    19861 gcctgatttt ctggataagt cccacaaact cttgttcatc aaagattgaa aagactcctt
    19921 ccaaggcttg aaggggcagt agaaaaggaa tccttggtcc catccattgt tcttgaaagg
    19981 atttgcctag ggagttggac cactggcata caaattgagc gttttctata ctcacctttt
    20041 cttcaaaacg aattgtcatc ttttcctcac catcttatct atgtttctcc attatactat
    20101 ttctcccatt ttttacgaat agataagtat gattgatttt tatttttttc tcgtcgggag
    20161 cattctcgct tcctttcttg gtttggtcat tgaccgtttt ccagagcaat ccattatcag
    20221 ttcagccagt cactgcgatt cctgtcagac tcccttgcgt cccttagatt tgattccgat
    20281 tctctcacag gtcttcaatc gctttcgctg tcgctactgc aaagttcgct atcctgtctg
    20341 gtatgccctc tttgaactag gcttaggact cctctttctg ctttactctt gggaattgct
    20401 ttccttgggg caagtcgtcc taatcaccgc tggtttgacc ttgggtatat acgactttca
    20461 ccatcaggaa tatcccttac tggtctggat gactttccac ctaatcctaa tagcttcctc
    20521 tggctggaat ctggtcatgg tctccttcct catacttgga attttggctc attttattga
    20581 tatccgcatg ggtgcagggg atttcctctt tttagcttct tgtgctctcg tctttagcgt
    20641 aacggagtta ctgatcttga ttcagttcgc ttctgcgacg ggtatcctgg cctttctcct
    20701 gcaaaagaaa aaggaaagac ttcctttcgt gcctttcctc ttacttgcta cttgtgtgat
    20761 tatttttggt aagctactac ttgtttgata aattccaatt tctgccatat gtactccatg
    20821 aaattatttc acagttaaat tataaattat ttcttttgta caaagggatg atgttatcaa
    20881 atcgatctgt tcttctatct tcttgatact gatcaaaaaa tttcatttcg actgaaaata
    20941 tttcgcttat aaactgtaaa cgaatacttt gtttagacat tatagtcgct agactgacta
    21001 gatgattact caaaacgacg tccagaatac tctttacttt gcttggtttt ttaacaaaaa
    21061 tttgatcatc caaaggttca atcattttgt aacctttttg cgcaatttga cgataaaagt
    21121 aagaatgttg ctttggagtc aataatccta acttaaaagc tcgatactct aaagcctgta
    21181 tcgaaacatt caaatccgac ttcaataaaa tataactatc aggattgctg acacgcttgc
    21241 caaccctctc ttcaaatttg actaaaaact cttcttttgg caataaaaaa catgatgcaa
    21301 aataatttgc ttcttgctcc aaacgatcgc catcttcatt catatcttta tatttatgta
    21361 aaagaatatg tcctagctca tgagctaaat caaaatttcg acgtacagat gatttattcg
    21421 ttcccaacac aatataaggt cttcccaatt ttgaccatgc gctataagca tcagcttggc
    21481 cattaattaa tcgttccacg atatagatgc ctgaacgttc taatttataa agcaaatcat
    21541 gattatcttt tgaaatacct aatttttccc tggcataaag agccaattcc tcaatggatt
    21601 ctcccttatg ataagattca ctcactacat tacttaggtc atgaattgta atattaggta
    21661 taattacaaa actttcaaaa taatcaatca aactatctac cttatgtaaa tacatagttt
    21721 gaatatctat tgttttccgg gttgctaggt ctgcatttct aaaggcaatt acagaagaat
    21781 caaatcgaat gctctcttct tcctgttcaa aataagttaa atcaacatga aattggttgg
    21841 ccaaatgcat tttggttgat aatttaggtt tcgtttcgtt ggactcaaac tgccaaatgg
    21901 cttgttccgt taaattaatt ctctgagcta attctgctct acttaaacca tttaacagcc
    21961 gtaattcttt caatacccga ccattaaaca tttacatact ccttactact tttgaccttc
    22021 ttgtttttct attcttggaa taatttcaaa atcttctgtt tccgataatt ctgaaaaatt
    22081 aggaatatct tgatatttag cttcttcgaa atggtacgaa cttgattgaa tatactcaga
    22141 caaatcttga atcaagtgta actgaccagt tcgtgcatca ggcataacaa catctacaga
    22201 tataatattg ttttctgagt ccgcctcata agttaaaatc ataaattttt cgatattcga
    22261 atttttagta gcttgttcaa tttcttgaat catttcatca gaaactaact ccatctgaat
    22321 tggaaaggaa tgactatctt catcattttt gtaggaagaa tgttgattaa gataaagtgt
    22381 attcatctga gcatattcaa ataagtagcc actcttattt ttttgtacca aaggaaattg
    22441 gttcgtaagt cgcttcttac cctttataat taacaatact ttcccatatt tttctgtgtt
    22501 tgtttcaaat tctaaatatc cccaagtctg tcctgctaat tgtaatttat actcaaacaa
    22561 atctgctgat gcaaatgcag tatcaatatg attaggtcgc gtccatgcat aaccattcga
    22621 cactatcatt gtctctcttt tttctagacg ttcatctaca taatcttttt gccctttcat
    22681 caaagtatct acaatttttt gtgcctcaag cgaatcaaag agatcctgat tcaacataat
    22741 tcttcctcct ccaaatactt tttaatgaat tatatcattt tcttaaagaa attactacaa
    22801 taattagctt tttcttaaag ttctgtgtca gagtaattta gaaaattata tcttctatag
    22861 taaaatcaat taaaaactga acaaatttat tgggaaattc aaatcacttt ctaaaaatat
    22921 tttaggaacc gtagtgtaat attccagatt caatttacta taaaactagc ctttctcctg
    22981 caaaagaaaa aggaaagact tcctttcgtg cctttcctct tacttgctac ttgtttaatt
    23041 atttttggta agctactgct tgtttgataa agtcctgaat cggctctcct tggtggagag
    23101 cttttactat tttcgaaccg acgataacac catctgacac cgcattgaag cgttccagat
    23161 cggcttgact agatacacca aaacctgtca agactgggat gtcggccact tgatgaagtt
    23221 gcgccaagtg cttgtccaaa tctgcacggt aattgcctga tttccctgtt accccattga
    23281 tggcaacggc atagacgaat ccctccgccc cttcaatcaa ctctttctgg cgctcaattc
    23341 ctgtggtcaa gcttactaaa ggaatcaagg cgatatctgt atctgccaaa aatggttcta
    23401 caaagttggc atgttcatga ggcaggtctg ggataatcaa gcccttcaca gctgtatcag
    23461 ccagatcttt gacaaagttc tccacaccgt actgaaagag ggggttgaag taggtcatga
    23521 tgaccagtgg aatctctgtt tcaatggttt tcaaggtttc aactaaagcc tgggtagagg
    23581 tcccgtgggc taaactgcgc aagccagctt cttcgataac aggtccatct gcaacagggt
    23641 ctgaaaaggg aatacccact tcaattgcag agacacccaa atcttctaaa aagtgaattg
    23701 tttcagcaag accatccaaa cctttttcgt ggtcaccagc catgatatag ggaacaaaaa
    23761 ttccttttcc agctgcttta atagcattta atttttttgt tagtgtctta ggcatgagct
    23821 tctcccttct ttgctgcatc tgcttccaag cggtctttta cttgaaccac atccttgtcc
    23881 ccacgacctg ataggcatac aatcatagac ttttctggtc caagttcttt ggccaatttc
    23941 accgcaaagg cgatagcatg gctagattcc aaagctggga taatcccttc cacacgagac
    24001 aagagttgga atccttccaa ggcttcttcg tctgtcacag ggacatagct ggcacgttta
    24061 atatcgtggt agtgagaatg ctctggaccg ataccaggat agtccaaacc tgctgagata
    24121 gagaaggctt caagaatttg accatgggca tcttggagca catccatgag ggaaccgtga
    24181 aggacacctg gacgaccctt ggtcaaggta gctgcgtggt gctccgtatc cacaccaaat
    24241 ccagccgctt cagctccata catggctact gactcatctt ctacaaaggg atggaagaga
    24301 ccgatggcat tcgacccacc accaacacag gctactaggg catctggcag attttgtcct
    24361 gtcaagtcac ggtactgttg tttagcctct cgaccaatga cactttggaa gtcacgaaca
    24421 atttctggaa atggatgagg ccccaaggca gaaccaagga tatagtgggt atcatctata
    24481 ttagccaccc atgaacgaag ggctgcattg accgcatcct tgagcacgcg cgaaccatct
    24541 gtcacggcct cgaccttagc tcccaaaagc tccatacgga agacattgag ggcttggcgt
    24601 ttgacatctt cctcacccat gtagatggta cattccatgt taaagagggc cgcagcagtt
    24661 gcagttgcca caccgtgctg accagcacca gtttctgcga taattttctt tttacccatg
    24721 cgtttggcaa gccaaacttg tcccaaggca ttgttaatct tgtgggctcc tgtatggtta
    24781 aggtcttccc gtttgagata aatcttggct ccgccgatat gctgggtcaa gttttttgcg
    24841 taataaagag gagtttcacg tcctacgtac tggcgcaaaa gctggtttaa ttcctcttgg
    24901 aaacttgggt ctgcctgact ttcacggtag gccttctcca actccaaaac tgctgtcatc
    24961 aatgtttctg ggacaaaacg tccgccgaat tttccgtaaa atccatcttt atttggttcc
    25021 tgatatgcca tgctttaccc tctctataaa tcttctaatc ttttcatgat ctttttgtcc
    25081 atctgtctcc actccgctcg atacatctac tgcataggga gtaaaatgtt gaattgcttt
    25141 tactacatta tcttcattaa ggccacctgc gataaagaag ggctgtgcta gtccagtcgt
    25201 atccagttga ccccaatcaa aggactgacc acttcctgcc acaggggcat caaagagtag
    25261 ataatctgcc tgagaattgg ggacatgccc atttccatct acctgcacag cctgaatact
    25321 ggcacaaggc aaattctcaa ataaatcagc tgccacctga ccgtgaactt gaaccaagtc
    25381 caagccaact ttgtcaatcg cttccagcag ttctacccga cttggtgaaa caaatactcc
    25441 aacctttttc acatctgcag gaataagctt tgccaactca gctgcctctt ctaaagtcac
    25501 ctgtctttta ctaggtgcaa agacaaaacc gatatagtcg gctcctgctg aaacggctgt
    25561 ttccaccgct tctttggtcg atagtccaca aattttaacc tttgtcaatc tgcaactcct
    25621 tgattctctg ggccacattt tctgcctgca taagagctgt ccctaccaaa attccgttaa
    25681 agtatggggc tagtcgttcc gcatcctgcc ctgtgaaaat ggcagattca gaaatgtaat
    25741 agcgaccttc ctcaaagtaa ggggctaaat ctacactggt ctgcaagtcg acctcaaagg
    25801 tagtcaagtt gcggttgttg accccgataa tctcagcacc aagtctgtgg gctacctcta
    25861 gttcagctag attgtgagtc tccactaaga cttccagacc aagctctgtc gcgtagtcat
    25921 acagttcctt gaggcgttct tcggacaagg ctgccacaat aagcaagata actgtcgcac
    25981 ctgtattgcg agcgcggatg atttgctttt catctatgat aaagtctttg ttgagcgtcg
    26041 gaatctctac ctgactggaa atttcccgta gataatccaa atgcccttta aagaaaacct
    26101 catctgtcaa caccgaaatc atcactgctc cgttttcttc ataagtctgg gcctgttgca
    26161 caatatccac atcgagattg atatctccca aactagggct agctttcttg acctcagcga
    26221 ttacctgcaa gcagtcctga tgattcttca aaaattctgc caagcgatag gtctggcgca
    26281 gaggctggat ttgctccagc ttcatctgct ccacctcacg cgccttctgc tctaagattc
    26341 gtgctaaaaa ttcctgactc atttttggta ctcctgtaac agtctgagtt tttcaagggc
    26401 cttgcctcta gcaatcactt gacgggccaa ggcaactcct tccttgatgc tatcaatctt
    26461 accattagca tagaaaccaa gaccagcatt caagactgtc gtttccaaga atggacttgc
    26521 ttcgtttttc agaacgctaa gcaaaatttc tgcattttcc tgagcattcc caccacgaat
    26581 atcttccata gcatagtctt ccattcccaa atcctctgga gtaaagcttg acaagctgat
    26641 ttcgccattt tcaagaagtg caatcttggt tgttccgttc aagccagctt catccaaccc
    26701 ttctggtcca gcaaccacga tggcacgttt gcgacccata tttttcaaaa cctgagctgt
    26761 actttctagg agttctggac gactaattcc aagaagctgt gtttctaaag ccattggatg
    26821 aatcagtgga ccagtcaagt tcataatcgt tggaattccc aattccaaac gagctggcat
    26881 gatgtatttc atagctgggt gcatattttt agcgaagaga aagacgattc cagttttatc
    26941 aaagacctta cctagttcag ctggtttgag gtcaagattg attcccaagg cttcgaggac
    27001 atctgcggaa ccagatttag aagaaatcga gcggttacca tgcttggcca tgtgaatacc
    27061 gccaccagcc aagacaaagg ctgcagttgt ggaaatatta aaactgaaag acttgtcccc
    27121 acctgtacca cagttgtcca tagcatcatg aatctcagtt ggaatatgct gggcatgtcc
    27181 tctcatgact tgggcaatgg ctgtacgttc ttcaggtgtt tcccccttca tcttaagagc
    27241 taagaggaga gaagcaatct gcgcttcagt tacacgccca gttacgatac gctcaatgac
    27301 atccgtcatt tccacacctg ataaattttc aaattttgct agtttttcaa taatctcttt
    27361 catcctagtt tcctcacttt acaaccttct cgataaaatt ccgaatagaa gacaagccgt
    27421 ctggcgttcc aatgctctct ggatggtact ggaagccata aatcggtagg tttttatgtt
    27481 gaatccccat gatggcttgg tcatcagtcg aacgagctgt cacttcaaag tcttctggca
    27541 tttcctcaat caaaatactg tgataacgca tgaccgcacg tccatcctca ataccttgat
    27601 acaaaacaga tggcgcttca aagttgatat tgctctgttt cccatgcatg acttttggag
    27661 ccaaacctag cttaccacca aagacttctg caatggcttg gtgacccaaa caaatcccta
    27721 gaatcggctt cttgcctgca aaatcacaaa tcatgtcttc catctttcca gcatcaactg
    27781 gccaaccagg accaggagaa aagaccagac catctgcttt ttcagcttct tcatacagct
    27841 tggaatcatc atttctcaaa acctgaactt ctgcaaaatt cccaatgtat tgggccaagt
    27901 tataggtaaa agaatcatag ttgtcaatca ataaaatcat ggtcttagtt ctccaattct
    27961 agtcatagat tttgctttgt taatggtttc ttggtattcg ttttgggcga tagagtcgta
    28021 gacaatccct gccccagcct gcacataggc tctttgattt ttgagaatca tggttcggat
    28081 ggcaatggcc aaatccatat cacccgtcgc agacaagtag ccgattgctc ctgcatatac
    28141 gctccgtttt tccgtttcca gttcatagat gcgtctcata gctcgaattt ttggtgctcc
    28201 agaaacggtt ccagcaggaa gcgttgcttt caaggcatcc atggcagtga gttctgcaag
    28261 caaacgtccc ttgaccacac tggtcaaatg catgacgtag cggaagagct ccacctccat
    28321 atacttagta acttggacac tggccgtttc agagatgcgg ccaatatcgt tacgccccaa
    28381 gtctaccaac attcgatgtt ctgctgtttc cttctcatca gagaggaggt cagtcgccaa
    28441 ggccttgtct tcttcatccg tagcccctct tggtcgcgtc cctgcaatcg gattggttgt
    28501 cacgatgcca tttttgacag aaaccaaact ttctggacta gctccgatga tttgataatc
    28561 cccaaaatca tagaaataaa ggtaattaga tggattagtc acgcggagat ttctgtagaa
    28621 gtcaaatgga tttccagtaa cttctgctga gaaacgctgg ctgagtacac attggaacat
    28681 atctccgtta cgaatcaagt cacgagctgt ttctaccatt ccctcaaact tatgtggagc
    28741 gatatgcggt ttgaagtcaa gtggtgataa atccaagtct tcaaattcat ttggagcagg
    28801 aatgcgtaat tcctcaagca cttggttcaa ggatttttcc aaggcctctt gactgcgctc
    28861 actataaagt gcatcctcta tgacatgtat cttctccttc ttgtggtcaa agaccatata
    28921 gctctcatag acaaagaaat gcatgtctgg cgtcccaatt gtatcctcag ggatttgacc
    28981 aatttcttca taaagcgaaa tcatatcgta accaacaaaa ccaatggctc ccccaccaaa
    29041 agggaggtct gaatggtgct ggctcttatg agtcacttca taaaggaaat ccaagggatc
    29101 ccgatcaatc gcttgaccat tttgatagag aactccattt tcaaacttaa tctcaaaaac
    29161 tggattatag gctaggatag aaaaacgagc tgtttccttg tctctcggaa tactctctaa
    29221 aataacctta tgttgcccct ttaagcgcat ataagccaag attggtgata agacatctcc
    29281 atgaatgatt cgttccattg tcatttccct ttcagttcta attctagttc gtggcgactg
    29341 tatgaaaaat ccccacgcaa aataacttgc gtgaggacga aattcgcggt gccacctcaa
    29401 ttataggatt tctcctatct ctcattcctg tctcagatat ctcctgtaac aggctgtgcg
    29461 ataaagggca ctcccttgag aatgatgttt tcttctctcg tttcagatga acccaacttt
    29521 acagctttct ctgcttgttt tcagcaacca caagctctct gtgagagaaa agactgtaat
    29581 ttttccatct attatttttt agcttctagt aatctgcaat cgcagctagg tccttgcctc
    29641 cacgaccaga gacattgatg aagagatgtt catctcggta cacctttata ctcttcgaaa
    29701 atctcttcaa accgcgtcaa cgtcgccttg ccgtaggtat ggttactgac ttcgtcagtt
    29761 ctatctgcaa cctcaaaaca gtgttttgag ctgacttcgt cagttctatc cacaacctca
    29821 aaacagtgtt ttgagcaacc tgcggctagt ttcctagttt gctctttgat tttcattgag
    29881 tattactagc ttttttcgta ttagtccagc ctttttgttt acttttagta ggaggcaagg
    29941 agctgtagat agaactcaag ttcatcaaag cgacttaagg ccctaataaa agataaacca
    30001 aacgacggat agaaaaaagc ccacacacag aatatacttc cgtgtgaggg cgttggtaac
    30061 gcggtgccac ctcaattata aagggactat ccctttacat ctctgccttg tttaacaaca
    30121 agctgcactg taaggtgtgc gcaccgaatt ttcattgttt caaattcatt ttcaaaatca
    30181 gcccactttc actacttcca accacctatt cacaatcacc acaggctccc tgaagatcaa
    30241 aaatagttac ttttctgatt tgttgaactt attttaatac tttgtttttt ctttgtcaag
    30301 acttttttac gatttttttg atatcattcg aatgtgacca tatcttcctt agatcgaaca
    30361 tgaacatgtc ccacttgtta gaaattggat ccaactcaat agaaactgaa tggaggctaa
    30421 acagaactta ttttagaaca ctccatcttt tccactagga ttttcaagaa ttaaacaata
    30481 ctagaaactc tgtctcctaa caaatttagg agaaacttca acagatgtga cactttcccc
    30541 tttaataatt gctaaaacac cttctatcat ttctttagcc aatttaacat aattgggagc
    30601 aattgtagac aaagctggag tataatactg agaaatagga atattatcaa atccaatgat
    30661 agaaatatca tctggaataa gaattccttt ctcatagcac gcacgaatca agccctgaac
    30721 cttttcatct cctgaaacaa aaataatgtc cggataattt tgggtagtca agtgctgcat
    30781 tgcataagaa taaactgaat caattgtaga taagccataa atgactttta aatccataaa
    30841 gtaattttta tcattcagaa aagaacgcac acctctttca cgatccttat taacatggga
    30901 ttctcctccc ataagcaacc acatattttt aaatttttct tcagttacag ctttcatcat
    30961 atcataagta gcttgaaaat tattattaga tacatagact actccagacg tttgagattc
    31021 accgaaaaca agaaaaggca tatggttctt ctttaaatac tgaattctga tatcatctac
    31081 actttcataa aaaacaataa caccatctac taggctacct gtgcttgata taattgaatt
    31141 actaattgta tcctcctctc caaagtactc aactatagca ttaacaccaa attctttaca
    31201 cgtccgtaac actttatcta acagcgtatg aaaccaaatt aaaggaaaag agtcgatttt
    31261 ttttacagaa atcaatatat ttatagcttc ttttttagtt aaattttttg catacgcatt
    31321 tggaatatac gacaattcct ctataacttt ttgaatcgct tgataagttt cttctttaac
    31381 atttactcca ccattaataa ctcgtgaaac tgtttttgga gaaaaacctg ataaacgtgc
    31441 aatatcataa atagttacct ttttcccatt tatatttttc atttcagtcc tccattacga
    31501 acattctaat attactatac aatatttaat tttttttaac aagagaattt agtaaattat
    31561 ttaagatcca caaattcaca aaattaattt tacaaatatt cttccccttc aaaaaaattt
    31621 aaattgcatt tcacaccttt atttttaaga atgtttccaa cttcacgaca aataaattca
    31681 tatgagaaaa aactgccata aaattgtaga ttaacttttt cagtaaaatg tgtaggattt
    31741 ataaaaacat ataatagcct gtcaatgtaa cattttaaca tagagttaat tttttcttta
    31801 aagataacat ttgttatcaa ctcatcagga ggtaaatgaa aggcaaacac catttcacaa
    31861 atatcataaa aagaaataaa tttgtatact tgtatcaaac aattattatc aaaatattct
    31921 attttaccta aatcaaaatt gattttataa tctttcataa aaacctctga gcaaaaatct
    31981 actcaaaaat tagatgatta aaacatctaa aaaacaaaag gacaaaaaca tctgtccctt
    32041 tgtttactaa atttcagcta atttcttcga cataaataac acctacaata ttagcaattt
    32101 cttccatcag tcgaagatgt tcaaatctac ctgataattc cagagtaata aatgacgcta
    32161 tttttttatc tggaacatca aagtattcaa ttctgtcaga attaacatct ccaaacgctg
    32221 ttcttgaatc ggtcattctg ataccatttt ctgcacaata aaccaataca cgattatagg
    32281 cttctgtaga tttaaccact atatacaatt caatcatttt agaacgattt tgtagatatt
    32341 tttttagtgg ttggaacatg gatatcacac cccaaacaga aatggctact aaaagagctc
    32401 cctcataaaa acctactcca atagctaatc caattcctgc cgaagcccaa atgcctgctg
    32461 cagttgtcag acctgtaatt ttctttttat ctgtaataag aatcgttcca gcgcctagaa
    32521 aacccacacc tgatataact tgagctccta atcgtgtagg atctcctgtc ccaaatttat
    32581 aagatacgta ttcattcgtc atcataatca aacatgcagc tagacaaaca atactataag
    32641 ttcggatgcc tgcaggctgg gatttgctcc ctctctctaa accaattata ctaccaatga
    32701 ctactgataa aacaatcctg acaactattt caatatttga taacccaaga ctagtggctg
    32761 tcatgattat ttccttactt tacgccccgg tctttgtgtg aagtataata ccgttccaga
    32821 aataatcatc agaacaattg tataaacaaa taccagagct tgtgcattag atgttgctgt
    32881 ttcatcacct gcagatcgaa tcgtaatacc taatggttga gctaggggat ggtaaaggaa
    32941 tacagataag tcgaagtcag ttaataaaga gttaaagttt aaagcaataa cagagagaac
    33001 aaccggtaaa ataaatggaa tgataacctt catcatagta taaaaaggtg aagcacccat
    33061 acttcttgct gcatcttcca tctcatcatc aacactaaat aaaatagcac gtaccattct
    33121 ataagaaaat gggattttta caactatata tgcaataagt agaattacca aactacctac
    33181 caaaatctga ttcaagacaa gaaattgtgg ctgattaaaa gtaaataata aacttactgc
    33241 taaaagcgta cttggtaata accaaggaag tagagcacca tattcaaata agaaatcaaa
    33301 acgagattta tgttttctga caacacgagc aaatacaact gcgagaattg ttgctgttgt
    33361 cgcagcaata atagaataaa taaagctgac caagaatgga gagaatgccg cactattact
    33421 aaagaataag cgataatttt ctaaagtaaa gtttgataat gttaagttac ctgtttgaat
    33481 tgcaactgga tctgtaaatg agtataatac tataaaaatt agtggaagca tgaaaactgt
    33541 gaacaatcca tatgctacaa tgtgagcaat gatattccaa ggcttagacg caattttttg
    33601 ttttttaaga ggcgctttag tcttagagat agaaatataa tttccacctt tttctatctt
    33661 attcatgata gtaagcaaaa ttgtagttgc aatacctaaa ataattgcaa gtaaggcagc
    33721 taaatcacga gaattcccca tccctgcaaa tgtaataatc attggattta tagtttgaaa
    33781 ttctttacca ccaacaatca tgggtgctgc tactgcagat aaaccactaa gaaaaaccat
    33841 aatagtaagt gcaaatagag ttggaattaa ggttggtaac actacttttc ggaaaacagt
    33901 aaatggtttt gctcccatat ttcgagcagc ctcaatagtg tgatagtcaa cgcttcgaat
    33961 tgtatttgtt aaaaacaatg tatgattagc agttcctgaa aatgtcataa tgaataagac
    34021 tgcaccatac ccaataaacc agttagggtc taaagaaggg ataacatttt gtaaaaattt
    34081 tgtaatcaat ccatatggac catagacaaa tttatatcca gtcgctaaaa ccactcctcc
    34141 ataaattaaa gaggtcatat aacctaattt taaaatttta gcacctttaa tatcaaagta
    34201 ctctgtaaat agaacacaaa gaatacctac gacattaact gtaataatga gtgaaaatgc
    34261 taacttaaaa ctgttcataa tactctgaag tgccctctga gattttagaa cacgatgtac
    34321 agcatcaagg gaaaattctc ctccttttac aaatacattc actactagat caaagtttgg
    34381 ataaataata aatgttacta agaaccagat taaccctaaa cgaataagcc aatcttttaa
    34441 atttaattta tgacgcatac tgcacctcct taaaattgca gaacgtctga tggtgtgata
    34501 aataattcca cactttctcc gacagatcta atagcagcct gactatcaat acttgttaca
    34561 ttaagaatct gactttcaga aacttttatt gtatagtgaa ttgtaactcc agaaaactca
    34621 acatcaataa ttgtcccttt tagaatgaaa tcttgttcag tttcacgatt gaatcgaact
    34681 ttctctaatc gaatgtatcc ttttttatct tctaagaaaa cgcttgtatt tttcagtaat
    34741 acttcgtgga ctgtttcatc ggtcaaaaca ttaatatctc caataaaatc acatacaaat
    34801 tcagtttgag aattatgata aatctctact ggtgtaccga cctgttcgat gtatccattg
    34861 ttaaagactg caattctatc agataaagtc aaggcttcct cttgatcatg agtaacatat
    34921 aaagtagtaa tacctaactc tttttgaagt cttttcaact cttttctcaa atctacacgt
    34981 aattttgcgt caaggtttga caatggttca tctagacaaa gaattttagg ttcaagaacc
    35041 agagcacgag ccaatgctac cctttgttgt tgacccccag ataattctga tacattacgc
    35101 tgtaactgtt gatcagagat cttaattttt gctgccactg ctgatacttt agctttaata
    35161 acatctggag ctaccttctt aacttttaaa ccaaatgcaa tattatcaaa aacagtcata
    35221 gttggaaata gcgcataaga ttgaaataca ataccaattc cacgcttttc aggttccaaa
    35281 tgagtgacat ctgttccatt aacttcaata cttcctgatg atggatctaa aaaacctacc
    35341 aatgctctca aagtagttga tttaccacat cctgaaggcc caagaaatgt aaagaattcc
    35401 ccttcatgta tatctaaatt cagattatca attgcaacaa aatcaccata tttaatttga
    35461 atattatcaa atttaatcat ctcactaact ccctctatta ctaaaccaaa agcctctctt
    35521 tatttcttcc ttaaatttag aaataataga gagacttgga cataaaaaat aactcttatt
    35581 tcttatttta cgtattctaa ttcagctttt tctacccatt catccaaatg ctttccaaca
    35641 gcttcccagt caatattttg tggtttcact tgatcaacaa attttttcgt atcttcaggt
    35701 aactctttta gggcatcttt atttgcagga atagatccaa attttttact atattctact
    35761 tgaatttctg attgaccaaa ccaatcaata aattctttag ctaacgcttg ttttttacta
    35821 gtgcttaaaa ccatagtttg ttcagttaca aatggtacac caatctcagg agtcataact
    35881 ttgaattcaa cattttgttc tttttgtccg attaacgctc cagaacccca gatcataccg
    35941 tattgaattg ggctttcttt atctaacgct ttaacaactg agctttcacc tttttgaaga
    36001 gtataggcat ttgcaaagta ttcttttgca acttcccatc ctttttctga tacgcctaaa
    36061 tctccttttt catcaaggta acgaactaag atacttgcta gaattgcccg tcctgtacca
    36121 ccttgaagac cataaattga atatttacct ttatacttac tacctaattc agtccaatct
    36181 ttaggcattt cttttacatc aggcgcccca attaaaacta atggttgaac aatcacagga
    36241 ttataataat tatctttatc tgataaagat tgatcaattt tatctaacca tttaggcttg
    36301 tactgtacta gtaatttttg atctctaatt ttatttgagt caacagcacc aattccaaat
    36361 accatatctg caactgcatt attcttctca gcaataacac ggtctgctaa ttgagcgcca
    36421 gcaatatcaa ccatttttat attaaaacca gcttcttttg ctttagcagt taaccaatca
    36481 ccacgaccat ttgagactga gttcgaatag attactaatt cttgactttt atcagctttt
    36541 tcttcagatg aagaagcagt cgtagaattt gaacctccag agcaagcagc aagtgtagta
    36601 agagcaactc ccgttgcaag tacagtagac caaactttca tttttttcat gataagttct
    36661 ccttttttat tattttattt aaatttttcg tgatatggaa caaattgtct catatcttca
    36721 aatacagtat agtcaatacg gtttacagta atagttggaa tcttctctaa taaaatttca
    36781 gttaattctg ctctgacttt agtaaactct tcttcctcct cttcggttag aggaatccga
    36841 agatacccaa ttgaaatatg gaattgatat ctatcatgat tagggaaaca aacacctgct
    36901 ttttctgaga cataagtacg aatttcttct aatctctttg cagaagcttc atctgcaggt
    36961 tcaactagta tgttttgttt tcccatttca gttatacgca tatgaatttc ttcatccaac
    37021 aatggaaaaa tttcaagttg tttagcaaag taatcatgta tttcctgtaa aggtgtatct
    37081 agaggaagat tactgctcca aaactccgtt tcacgatttt catggcacaa caattcaatt
    37141 acagtcatgt gaatagaatt ccttggagtt aaagtaaact tatcgataaa tggtaattct
    37201 ctataacgtg attgaataat atcaacaact tccatcaaat cttgtttagt ataaagattt
    37261 gctacaactg tattcccagg gaaatgatta aattccccat tctctttgaa cttaattttt
    37321 gttaagtttt tcatataaag accttctttt ttatatttga catcggtgtc attgtgttta
    37381 cattatacaa tgaaaccgtt tcctttgtca agcgctgtca aacatttttt ttaatttatc
    37441 tttcattaaa ag
//
LOCUS       DAVBDR010000014        37347 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.014, whole genome shotgun sequence.
ACCESSION   DAVBDR010000014 DAVBDR010000000
VERSION     DAVBDR010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 37347)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37347)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37347
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.014"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            232..1995
                     /gene="aspS"
                     /locus_tag="VQ540_000743"
     CDS             232..1995
                     /gene="aspS"
                     /locus_tag="VQ540_000743"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HET2544576.1"
                     /translation="MKRSMYAGRVREEHIGQEITLKGWVGRRRDLGGLIFIDLRDREG
                     IMQLVINPEKVSAEVMATAESLRSEFVIEVTGQVAAREQANDKLPTGAVELNVTALIV
                     LNTAKTTPFEIKDGIEANDDTRLRYRYLDLRRPEMLENLKLRAKVTHSIRNYLDELEF
                     IDVETPFLSKSTPEGARDYLVPSRVNKGHFYALPQSPQITKQLLMNAGFDRYYQIVKC
                     FRDEDLRGDRQPEFTQVDLETSFLTEKEIQDITEGLIARVMKETKGIEVTLPFPRMKY
                     DDAMALYGSDKPDTRFDMLLQDLTEVVKGVDFKVFSEAPAVKAIVVKGAADNYSRKDI
                     DKMTEVAKQYGAKGLAWVKVVDGELNGPVAKFLTGIQEELTTALALEDKDLVLFVADT
                     LEVVNATLGTLRGRIAKELGLIDNDKFNFLWVVDWPMFEWSEEEGRYMSAHHPFTLPQ
                     EETAHELEGDLAKVRAIAYDIVLNGYELGGGSLRINQKDLQERMFKALGFSTEEANDQ
                     FGFLLEAMDYGFPPHGGLAIGLDRFVMLLAGEENIREVIAFPKNNKATDPMTQAPSTV
                     ALKQLEELSLQVEEDETNKTN"
     gene            1973..2914
                     /locus_tag="VQ540_000744"
     CDS             1973..2914
                     /locus_tag="VQ540_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HET2544577.1"
                     /translation="MKQTKRIKRWRYYLRRFAYQIKILRVLQSISREKYDEKISASLV
                     YGFLSAVAVNFFFQPGHVYSSGATGLAQIISALSNHWFGFHIPISLSFYAINFPLMVL
                     AWYQIGHKFTVFTFITVSMSSFFIQFVPVATLTEDPIINSLFGGVVMGLGIGFALRNN
                     ISSGGTDIVSLTIRKKTGKNVGSISFLVNGTIMLIAGLTFGWKYALYSMITIFVSSRV
                     TDAVFTKQKRMQAMIVTNHPEKVIEKIHKKLHRGATMIHDAEGTYNHERKAVLITVIT
                     RAEFNEFKQIMTQVDPSSFVSVSENVHILGRFVEIDN"
     gene            complement(3034..3114)
                     /locus_tag="VQ540_000745"
                     /pseudo
     CDS             complement(3034..3114)
                     /locus_tag="VQ540_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(3250..4236)
                     /locus_tag="VQ540_000746"
     CDS             complement(3250..4236)
                     /locus_tag="VQ540_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HET2544578.1"
                     /translation="MPVTIKDVAKAAGVSPSTVTRVIQNKSTISDETKKRVRKAMKEL
                     NYHPNLNARSLVSSYTQVIGLVLPDDSDAFYQNPFFPSVLRGISQVASENHYAIQIAT
                     GKDEKERLNAISQMVYGKRVDGLIFLYAQEEDPLVKLVAEEQFPFLILGKSLSPFIPL
                     VDNDNVQAGFDATEYFIKKGCKRIAFIGGSKKLFVTKDRLTGYEQALKHYKLTTDNNR
                     IYFADEFLEEKGYKFSKRLFKHDPQIDAIITTDSLLAEGVCNYIAKHQLDVPVLSFDS
                     VNPKLNLAAYVDINSLELGRVSLETILQIINDNKNNKQICYRQLIAHKIIEK"
     gene            complement(4246..5046)
                     /locus_tag="VQ540_000747"
     CDS             complement(4246..5046)
                     /locus_tag="VQ540_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000938258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HET2544579.1"
                     /translation="MLPYPFSYFSSIWGFRKPLSKRFELNWFQLLFTSIFLISLSMVP
                     IAIQNSSQETYPLETFIDNVYEPLTNEVVQDLSEHATIVDGTLTYTGTASQAPSVVIG
                     PSQIKELPKDLQLHFDTNELVISKESKELTRISYRAIQTESFKSKDSLTQAISKDWYQ
                     QNRIYISLFLVLGASFLFGLNFFIVSLGASLLLYITKKSRLFSFRTFKECYHFILNCL
                     GLPTLITLILGLFGQNMTTLITVQNILFVLYLVTIFYKTHFRDPNYHK"
     gene            complement(5307..6149)
                     /locus_tag="VQ540_000748"
     CDS             complement(5307..6149)
                     /locus_tag="VQ540_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001065636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET2544580.1"
                     /translation="MNNSIKLKRRLTQSLTYLYLIGLSIVIIYPLLITIMSAFKAGNV
                     SAFKLDTNIDLNFDNFKGLFTETLYGTWYLNTLIIALITMAVQTSIIVLAGYAYSRYN
                     FLARKQSLVFFLIIQMVPTMAALTAFFVMALMLNALNHNWFLIFLYVGGGIPMNAWLM
                     KGYFDTVPMSLDESAKLDGAGHFRRFWQIVLPLVRPMVAVQALWAFMGPFGDYILSSF
                     LLREKEYFTVAVGLQTFVNNAKNLKIAYFSAGAILIALPICILFFFLQKNFVSGLTSG
                     GDKG"
     gene            complement(6151..7443)
                     /locus_tag="VQ540_000749"
     CDS             complement(6151..7443)
                     /locus_tag="VQ540_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000414940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET2544581.1"
                     /translation="MEKQQPSKAALLSIIPGLGQIYNKQKAKGFIFLGVTIVFVLYFL
                     ALATPELSNLITLGNKPGRDNSLFMLIRGAFHLIFVIVYVLFYFSNIKDAHTIAKRIN
                     NGIPVPRTLKDMIKGIYENGFPYLLIIPSYVAMTFAIIFPVIVTLMIAFTNYDFQHLP
                     PNKLLDWVGLTNFTNIWSLSTFRSAFGSVLSWTIIWALAASTLQIVIGIFTAIIANQP
                     FIKGKRIFGVIFLLPWAVPAFITILTFSNMFNDSVGAINTQVLPILAKFLPFLDGALI
                     PWKTDPTWTKIALIMMQGWLGFPYIYVLTLGILQSIPNDLYEAAYIDGANAWQKFRNI
                     TFPMILAVAAPTLISQYTFNFNNFSIMYLFNGGGPGSVGGGAGSTDILISWIYRLTTG
                     TSPQYSMAAAVTLIISIIVISISMIAFKKLHAFDMEDV"
     gene            complement(7554..8825)
                     /locus_tag="VQ540_000750"
     CDS             complement(7554..8825)
                     /locus_tag="VQ540_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000095461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HET2544582.1"
                     /translation="MSSKFMKSTAVLGTATLASLLLVACGSKTADKPADSGSSEVKEL
                     TVYVDEGYKSYIEEVAKAYEKEAGVKVTLKTGDALGGLDKLSLDNQSGNVPDVMMAPY
                     DRVGSLGSDGQLSEVKLSDGAKTDDTTKSLVTAANGKVYGAPAVIESLVMYYNKDLVK
                     DAPKTFADLENLAKDSKYAFAGEDGKTTAFLADWTNFYYTYGLLAGNGAYVFGQNGKD
                     AKDIGLANDGSIVGINYAKSWYEKWPKGMQDTEGAGNLIQTQFQEGKTAAIIDGPWKA
                     QAFKDAKVNYGVATIPTLPNGKEYAAFGGGKAWVIPQAVKNLEASQKFVDFLVATEQQ
                     KVLYDKTNEIPANTEARSYAEGKNDELTTAVIKQFKNTQPLPNISQMSAVWDPAKNML
                     FDAVSGQKDAKTAANDAVTLIKETIKQKFGE"
     gene            9375..10892
                     /gene="malQ"
                     /locus_tag="VQ540_000751"
     CDS             9375..10892
                     /gene="malQ"
                     /locus_tag="VQ540_000751"
                     /EC_number="2.4.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-alpha-glucanotransferase"
                     /protein_id="HET2544583.1"
                     /translation="MKKRQSGVLMHISSLPGAYGIGSFGQSAYDFVDFLVRTKQRYWQ
                     ILPLGATSYGDSPYQSFSAFAGNTHFIDLDILVEQGLLEASDLEGVDFGSDASEVDYA
                     KIYYARRPLLEKAVKRFFEVGDVKDFEKFAQDNQSWLELFAEYMAIKEYFDNLAWTEW
                     PDADARARKASALESYREQLADKLVYHRVTQYFFFQQWLKLKAYANDNHIEIVGDMPI
                     YVAEDSSDMWANPHLFKTDVNGKATCIAGCPPDEFSVTGQLWGNPIYDWEAMDKDGYK
                     WWIERLRESFKIYDIVRIDHFRGFESYWEIPAGSDTAAPGEWVKGPGYKLFAAVKEEL
                     GELNIIAEDLGFMTDEVIELRERTGFPGMKILQFAFNPEDESIDSPHLAPANSVMYTG
                     THDNNTVLGWYRNEIDDATREYMARYTNRKEYETVVHAMLRTVFSSVSFMAIATMQDL
                     LELDEAARMNFPSTLGGNWSWRMTEDQLTPAVEEGLLDLTTIYRRINENLVDLKK"
     gene            10918..13176
                     /locus_tag="VQ540_000752"
     CDS             10918..13176
                     /locus_tag="VQ540_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000950172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan phosphorylase"
                     /protein_id="HET2544584.1"
                     /translation="MLSLQEFVQNRYNKTIAECSNEELYLALLNYSKLASSQKPVNTG
                     KKKVYYISAEFLIGKLLSNNLINLGLYDDVKKELAAAGKDLIEVEEVELEPSLGNGGL
                     GRLAACFIDSIATLGLNGDGVGLNYHFGLFQQVLKNNQQETIPNAWLTEQNWLVRSSR
                     SYQVPFADFTLTSTLYDIDVTGYETATKNRLRLFDLDSVDSSIIKDGINFDKTDIARN
                     LTLFLYPDDSDRQGELLRIFQQYFMVSNGAQLIIDEAIEKGSNLHDLADYAVVQINDT
                     HPSMVIPELIRLLTARGIDLDEAISIVRSMTAYTNHTILAEALEKWPLEFLQEVVPHL
                     VPIIEELDRRVKAEYKDPAVQIIDESGRVHMAHMDIHYGYSVNGVAALHTEILKNSEL
                     KAFYDLYPEKFNNKTNGITFRRWLMHANPRLSHYLDEILGDGWHHEADELEKLLSYED
                     KAAVKEKLESIKAHNKRKLARHLKEHQGVEINPNSIFDIQIKRLHEYKRQQMNALYVI
                     HKYLDIKAGNIPARPITIFFGGKAAPAYTIAQDIIHLILCMSEVIANDPAVAPHLQVV
                     MVENYNVTAASFLIPACDISEQISLASKEASGTGNMKFMLNGALTLGTMDGANVEIAE
                     LVGEENIYIFGEDSETVIDLYAKAAYKSSEFYAREAIKPLVDFIVSDAVLAAGNKERL
                     ERLYNELINKDWFMTLLDLEDYIKVKEQMLADYEDRDAWLDKVIVNISKAGFFSSDRT
                     IAQYNEDIWHLN"
     gene            complement(14220..14792)
                     /locus_tag="VQ540_000753"
     CDS             complement(14220..14792)
                     /locus_tag="VQ540_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2544585.1"
                     /translation="MNKLMKFISVFLTSIVLIVSAIPSVSAVYASEQVSQIETNMELQ
                     PVTSLTEEQINTLANEIQSFHPDVSQQWIKEVINRQLQGDYTIPPTYSPFRAAWQGIT
                     VNQMGALLDTAIALALGGTTAGLANLIKVKGKHAAKSAIRSAISRYLGSWFVNDVALE
                     FAINLLSPGTYLAQLWDKNDAIPNNGRINF"
     gene            complement(15414..16262)
                     /locus_tag="VQ540_000754"
     CDS             complement(15414..16262)
                     /locus_tag="VQ540_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HET2544586.1"
                     /translation="MNTNLKPKLQRFASATAFACPICQENLTLLETNFKCCNRHSFDL
                     AKFGYVNLAPQIKQSANYDKENFQNRQQILEAGFYQAILDAVSDLLASSKTTTTILDI
                     GCGEGFYSRKLQESHSEKTFYAFDISKDSVQIAAKSEPNWAVNWFVGDLARLPIKDAN
                     MDILLDIFSPANYGEFRRVLSKDGILIKVIPTENHLKEIRQRVQDQLTNKEYSNQDIK
                     EHFQEHFTILSSQTASLTKTITAEQLQALLSMTPLLFHVDQSKIDWSQLTEITIEAEI
                     LVGKAF"
     gene            16407..16685
                     /locus_tag="VQ540_000755"
     CDS             16407..16685
                     /locus_tag="VQ540_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003075836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2544587.1"
                     /translation="MLKEVLTVAKVAKKSSLFLGGVAFGTLGLKILASKEAKKGYSKA
                     LAKAYKLKDELDASVSVVKQHGDDVLQDAKYLYEQEKKEEQLDSLIGE"
     gene            16687..18750
                     /locus_tag="VQ540_000756"
     CDS             16687..18750
                     /locus_tag="VQ540_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000008803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HET2544588.1"
                     /translation="MSFKVLHRGYQHIRLSSSFSLTLDIQDYLRSLARDEKGIESIQF
                     YMDQQHFTLRIKEGFSVLDNAEAFLKRIDKGKVSELMTLPIRREESAYSIVSGAAVKR
                     VLFRSFVPYPIRYIWTCYQALGYIREAYQTLARKELTMEVLDCSAILLSLFMNQSKTA
                     SNIMFMLDLGNHLDQWSLKKTATDLEQSLLAKESDVFLVQGDTVVSIKSSDVQIGDVL
                     ILSQGNEILFDGQVVSGLGMVNESSLTGESFPVEKRESDLVCANTVLETGELRIRVTD
                     NQMNSRILQLIELMKKSEENKKTKQRYFIKMADKVVKYNFLGAGLTYLLTGSFSKAIS
                     FLLVDFSCALKISTPVAYLTVIKEGLNREMVIKDGDVLEKYLEVDTFLFDKTGTITTS
                     YPIVEKVLPFGDYSEEDILRISACLEEHIYHPIANAIVKQAEIEGIEHEEMHGKLQYI
                     ASKGIKSHIDGQPVLIGNYVLMQDEQIHISSEQNALIEEYKSHYNLLFLAYQNELIGM
                     FCIHTPLRKEAKTALDKLKAQGKKLILATGDTLIRTEELVKDLPFDQVYTDLKPDGKF
                     ELVEKLQKAGHTILMVGDGLNDSAALTLSDIGVVMNESADISKQMSDILLLDNRLDFF
                     QELDSLSSSLQTLIKKNIQDTVVVNSSLIGFGLFNWFSPSNLSILHNLTTLRIVLRSL
                     SIKNR"
     gene            complement(18828..20084)
                     /locus_tag="VQ540_000757"
     CDS             complement(18828..20084)
                     /locus_tag="VQ540_000757"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HET2544589.1"
                     /translation="MHIFDELKERGLIFQTTDEEALRKALEEGQVSYYTGYDPTADSL
                     HLGHLVAILTSRRLQLAGHKPYALVGGATGLIGDPSFKDAERSLQTKDTVDGWVKSIQ
                     GQLSRFLDFENGENKAVMVNNYDWFGSISFIDFLRDIGKYFTVNYMMSKESVKKRIET
                     GISYTEFAYQIMQGYDFFVLNQDHNVTLQIGGSDQWGNMTAGTELLRRKADKTGHVIT
                     VPLITDATGKKFGKSEGNAVWLNPEKTSPYEMYQFWMNVMDADAVRFLKIFTFLSLDE
                     IEDIRKQFEAAPHERLAQKVLAREVVTLVHGEEAYKEALNITEQLFAGNIKNLSVKEL
                     KQGLRGVPNYQVQADENNNIVELLVSSGIVNSKRQAREDVQNGAIYVNGDRIQDLDYV
                     LSDADKLENELTVIRRGKKKYFVLTY"
     gene            20226..22691
                     /locus_tag="VQ540_000758"
     CDS             20226..22691
                     /locus_tag="VQ540_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HET2544590.1"
                     /translation="MQNQLNELKRKMLEFFQQKQKNKKSARPGKKGSSTKKSKTLDKS
                     AIFPAILLSIKALFNLLFVLGFLGGMLGVGIALGYGVALFDKVRVPQTEELVNQVKDI
                     SSISEITYSDGTVIASIESDLLRTSISSEQISENLKKAIIATEDEHFKEHKGVVPKAV
                     IRATLGKFVGLGSSSGGSTLTQQLIKQQVVGDAPTLARKAAEIVDALALERAMNKDEI
                     LTTYLNVAPFGRNNKGQNIAGARQAAEGIFGVDASQLTVPQAAFLAGLPQSPITYSPY
                     ENTGELKSDEDLEIGLRRAKAVLYSMYRTGALSKDEYSQYKDYDLKQDFLPSGTVTGI
                     SRDYLYFTTLAEAQERMYDYLAQRDNVSAKELKNEATQKFYRDLAAKEIENGGYKITT
                     TIDQKIHSAMQSAVADYGYLLDDGTGRVEVGNVLMDNQTGAILGFVGGRNYQENQNNH
                     AFDTKRSPASTTKPLLAYGIAIDQGLMGSETILSNYPTNFANGNPIMYANSKGTGMMT
                     LGEALNYSWNIPAYWTYRMLREKGVDVKGYMEKMGYEIPEYGIESLPMGGGIEVTVAQ
                     HTNGYQTLANNGVYHQKHVISKIEAADGRVVYEYQDKPVQVYSKATATIMQGLLREVL
                     SSRVTTTFKSNLTSLNPTLANADWIGKTGTTNQDENMWLMLSTPRLTLGGWIGHDDNH
                     SLSRRAGYSNNSNYMAHLVNAIQQASPSIWGNERFALDPSVVKSEVLKSTGQKPGKVS
                     VEGKEVEVTGSTVTSYWANKSGAPATSYRFAIGGSDADYQNAWSSIVGSLPTPSSSSS
                     SSSSSSDSSNSSTTRPSSSRARR"
     gene            22756..23667
                     /locus_tag="VQ540_000759"
     CDS             22756..23667
                     /locus_tag="VQ540_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HET2544591.1"
                     /translation="MNQYQKKIVNGKIYSLLSGLIWGICGILGEYFFTHYQVSSGWIT
                     SMRLTLAGSLVLIWSAIQLKSQVLDIWRDKKNYLPFLAYAILGIFSVQYFFYLCLEYS
                     NATTATILQFISPVFILFYNRLVYQKRASKSAVFYVLVAMLGVCLMATKGDLSQLSMT
                     PLALITGLLSAMGVMFNVILPQPFAKRYGFVPTVGWGMILAGLFSNVLSPVYQLSFTL
                     DIWSILICLIIAFFGTAFAFFISMKAVSLVSPLVVSVISASEPLSSALLSVLFLGLVV
                     DWSLLLAIALIILPMIFLSIEEAKESR"
     gene            23897..24595
                     /gene="dapD"
                     /locus_tag="VQ540_000760"
     CDS             23897..24595
                     /gene="dapD"
                     /locus_tag="VQ540_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HET2544592.1"
                     /translation="MTATKMNAQEIIQFIANAEKKTSVKVTFEGQLATAVPSSVVKLG
                     NVLFGDWKDVAPLLEGLVENQDYVVEQDARNSAVPLLDKRAINARIEPGAIIRDQVEI
                     GDNAVIMMGAVINIGAEIGAGTMIDMGAILGGRAIVGKNSHVGAGAVLAGVIEPASAE
                     PVCVGDNVLIGANAVVIEGVQIGSGSVVAAGAIVTQDVPENVVVAGVPARIIKEIDAQ
                     TQQKTALEDALRTL"
     gene            24663..25793
                     /locus_tag="VQ540_000761"
     CDS             24663..25793
                     /locus_tag="VQ540_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyldiaminopimelate deacetylase"
                     /protein_id="HET2544593.1"
                     /translation="MLDLIQTRRALHQIPEIGLEEFKTQAYLLDVIEKLTTGKDFVQI
                     RTWRTGILVYLQGSQPERTIGWRTDIDGLPIVEQTGLPFTSQHQGRMHACGHDFHMTI
                     ALGCLERALEEQPKNNLLFLFQPAEENEAGGMLMYEDGAFGDWLPNQFYGLHVRPDLK
                     VGQIATNTHTLFAGTCEVKIRFKGKGGHAAFPHEANDALVAASYFVTQVQSVVSRNVN
                     PIEGAVVTFGVFQAGTTNNVITDTAFLHGTIRALTQDMSLLVQKRVKTVAEGVAAAFD
                     MEVEVELKQGGYLPVENNPALARELMDFFDEKDGIELIDIEPAMTGEDFGYLLSKVDG
                     VMFWLGIDSPYALHHPQMSPKEEVLAIGVAAVSSFLKKKAAE"
     gene            25805..26344
                     /locus_tag="VQ540_000762"
     CDS             25805..26344
                     /locus_tag="VQ540_000762"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HET2544594.1"
                     /translation="MKSELRKQVLHEMKAISQEQKQAIDQALTERILQHPFYQEAKVI
                     ATYLSFSHEFQTRELIEQALKDGKKVLTPKTYPKGRMDFVVYDPQQLVKTSFALLEPQ
                     GDLEVVDASQIDLIHVPGLAFTTDGYRIGYGGGYYDRYLEHFSGRALSTIYPCQIQDF
                     IPENHDIPVQEVLIDEGNL"
     gene            26328..27005
                     /locus_tag="VQ540_000763"
     CDS             26328..27005
                     /locus_tag="VQ540_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HET2544595.1"
                     /translation="MKEIFDRRYPVTSFFLLVTALVFLLMLVTAGGNFDRADTLFRFG
                     AMYGPAIRLFPEQVWRLLSAIFVHIGWEHFIVNMLSLYYLGRQVEEIFGSKQFFFLYL
                     LSGMMGNLFVFVFSPKSLAAGASTSLYGLFAAIIVLRYATRNPYIQQLGQSYLTLFVV
                     NIIGSVLIPGISLAGHIGGAVGGAFLAVIFPVRGEKRMYNTSQRLGAVVLFVGLAILL
                     FYKGMGM"
     gene            complement(27077..27976)
                     /gene="galU"
                     /locus_tag="VQ540_000764"
     CDS             complement(27077..27976)
                     /gene="galU"
                     /locus_tag="VQ540_000764"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HET2544596.1"
                     /translation="MTSKVRKAVIPAAGLGTRFLPATKALAKEMLPIVDKPTIQFIVE
                     EALKSGIEDILVVTGKSKRSIEDHFDSNFELEYNLKEKGKTDLLKLVDKTTDMRLHFI
                     RQTHPRGLGDAVLQAKAFVGNEPFVVMLGDDLMDITDEKAVPLTKQLMDDYERTHAST
                     IAVMPVPHDEVSAYGVIAPQGEGKDGLYSVETFVEKPAPEDAPSDLAIIGRYLLTPEI
                     FQILENQAPGAGNEIQLTDAIDTLNKTQRVFAREFNGARYDVGDKFGFMKTSIDYALK
                     HPQVKDDLKNYLIQLGKELTEKE"
     gene            complement(27998..29014)
                     /locus_tag="VQ540_000765"
     CDS             complement(27998..29014)
                     /locus_tag="VQ540_000765"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000415108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HET2544597.1"
                     /translation="MEKQTVAVLGPGSWGTALSQVLNDNGHEVRIWGNLPEQINEINT
                     YHTNKHYFKDVVLDENIIAYTDLAETLKDVDAILFVVPTKVTRLVAQQVAQTLDHKAI
                     IMHASKGLEPDSHKRLSTILEEEIPEQLRSDIVVVSGPSHAEETIVRDLTLITAASKD
                     LQTAQYVQELFSNHYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGFGDNAKAAII
                     ARGLAEITRLGVALGASPLTYSGLSGVGDLIVTGTSIHSRNWRAGDALGRGESLADIE
                     ANMGMVIEGISTTRAAYELAQELGVYMPITQAIYQVIYHGTNIKDAIYDIMNNEFKAE
                     NEWS"
     gene            29226..29603
                     /locus_tag="VQ540_000766"
                     /pseudo
     CDS             29226..29603
                     /locus_tag="VQ540_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809823.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            complement(29783..30208)
                     /locus_tag="VQ540_000767"
     CDS             complement(29783..30208)
                     /locus_tag="VQ540_000767"
                     /inference="COORDINATES: protein motif:HMM:NF025080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2544598.1"
                     /translation="MNNLSSVDSEELFQFYRERGNAENFIKERKAGFFGDKTDSSTMI
                     KNEVRMMMGCLAYNLYLFLKQLAGDEVKSLTIKRFRRLFLHIAGKYVSTARRHILKFS
                     SLYAYSKQFQALFDTICQINLILPVPYRARGQGKTCLTE"
     gene            complement(30276..30926)
                     /gene="phoU"
                     /locus_tag="VQ540_000768"
     CDS             complement(30276..30926)
                     /gene="phoU"
                     /locus_tag="VQ540_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HET2544599.1"
                     /translation="MRNQFDLELHELEQSFLGLGQLVLETASKALLALASKDKEMAEL
                     IINKDHAINQGQSAIELTCARLLALQQPQVSDLRFVISIMSSCSDLERMGDHMAGIAK
                     AVLQLKENQLAPDEEQLHQMGKLSLSMLADLLVAFPLHQASKAISIAQKDEQIDQYYY
                     ALSKEIIGLMKDQETSIPNGTQYLYIIGHLERFADYIANICERLVYLETGELVDLN"
     gene            complement(30941..31693)
                     /gene="pstB"
                     /locus_tag="VQ540_000769"
     CDS             complement(30941..31693)
                     /gene="pstB"
                     /locus_tag="VQ540_000769"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003101281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HET2544600.1"
                     /translation="MGTFSVRHLDLFYGDFQALKNISIQLPERQITALIGPSGCGKST
                     FLKTLNRMNDLVPSCHIEGQVLLDEQDIYSSKFNLNQLRKRVGMVFQQPNPFAMSIYD
                     NVAYGPRTHGIRDKKQLDALVEKSLKGAAIWEEVKDDLKKSAMSLSGGQQQRLCIARA
                     LAVEPDVLLMDEPTSALDPISTLKIEDLIQQLKKDYTIIIVTHNMQQASRISDKTAFF
                     LTGEICEFGDTVDVFTNPKDQRTEDYISGRFG"
     gene            complement(31695..32510)
                     /gene="pstA"
                     /locus_tag="VQ540_000770"
     CDS             complement(31695..32510)
                     /gene="pstA"
                     /locus_tag="VQ540_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HET2544601.1"
                     /translation="MSKYLLKLLVYCFSALTFGSLFLIIGFILIKGLPHLSLSLFSWT
                     YTSENISLMPAIISTVILVFGALLLALPIGIFAGFYLVEYTKKDSLCVKIMRLASDTL
                     SGIPSIVFGLFGMLFFVVFLGFQYSLLSGILTSVIMVLPVIIRSTEEALLSVSDSMRQ
                     ASYGLGAGKLRTVFRIVLPVAMPGILAGVILAIGRIVGETAALMYTLGTSTNTPSSLM
                     SSGRSLALHMYMLSSEGLHVNEAYATGVILIITVLMINTLSSLLSRKLVKGAS"
     gene            complement(32503..33366)
                     /gene="pstC"
                     /locus_tag="VQ540_000771"
     CDS             complement(32503..33366)
                     /gene="pstC"
                     /locus_tag="VQ540_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HET2544602.1"
                     /translation="MTKQAFKEAVFRAIFFMSATVAVVAILLICFFIFSNGLPFMANY
                     GFARFLLGSDWSPTNIPASYGILPMIVGSLLITLGAIVIGVPTGILTSVFMVYYCPKP
                     VYGFLKSAINLMAAIPSIVYGFFGLQLLVPWIRTFLGNGMSVLTASLLLGIMILPTII
                     SLSESAIRTVPKTYYSGSLALGASHERSIFSVILPAARSGILSAVILGIGRAVGETMA
                     VILVAGNQPIIPSGLFSGTRTLTTNIVLEMAYASGQHREALIATSAVLFFLILLINAY
                     FAYLKGKSSYE"
     gene            complement(33484..34359)
                     /locus_tag="VQ540_000772"
     CDS             complement(33484..34359)
                     /locus_tag="VQ540_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate-binding protein"
                     /protein_id="HET2544603.1"
                     /translation="MKFKKMLTLAAIGLSGFGLVACGNQSAASKQSASGTIEVISREN
                     GSGTRGAFTEITGILKKDGDKKIDNTAKTAVIQNSTEGVLSAVQGNANAIGYISLGSL
                     TKSVKALEIDGVKASRDTVLDGEYPLQRPFNIVWSSNLSKLGQDFISFIHSKQGQQVV
                     TDNKFIEAKTETTEYTSQHLSGKLSVVGSTSVSSLMEKLAEAYKKENPEVTIDITSNG
                     SSAGITAVKEKTADIGMVSRELTPEEGKSLTHDAIALDGIAVVVNNDNKASQVSMAEL
                     ADVFSGKLTTWDKIK"
     gene            complement(34526..35857)
                     /locus_tag="VQ540_000773"
     CDS             complement(34526..35857)
                     /locus_tag="VQ540_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HET2544604.1"
                     /translation="MKRYLQFWLVNLSVSLILIAGMALTWISKGIGLFLLALSLGQGG
                     YWLFCLWKWEVAFETLHQPLLTSSEYFLEKGQEDLKSLAQYVSALKTKVSQQDQQYKD
                     LAETMEVLLSHLTMGTFLVSAQGQMLLSSRSLPHYFPDVDGDISSLDDLKRMDIRNLV
                     HQAFDQKTRLKQEVSGFHEGDLILEVTAVPVFSPTQSVEAVLVLLYDLTTIRTYEKLN
                     LAFVSNASHELRTPVTSIKGFAETIKGMSAEEEALKDDFLDIIYKESLRLEHIVEHLL
                     TLSKAQQMPIQWTTLSLAEFVQDLTQSLQPQLKKKDLQLKVQVPDDVTLVSDSQLLSQ
                     ILLNLLSNAIRYTEQGGKIEVKTQKVNEGIKISVSDTGIGISQLEQDRIFERFYRVNK
                     GRSRQTGGTGLGLAIVKELSQLLGGQVTVTSQLGRGSCFTIFLPNQSFAQD"
     gene            complement(35858..36565)
                     /locus_tag="VQ540_000774"
     CDS             complement(35858..36565)
                     /locus_tag="VQ540_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET2544605.1"
                     /translation="MTKQVLLVDDEEHILKLLDYHLSKEGFSTQLVTNGRKALALAET
                     EPFDFILLDIMLPQLDGMEVCKRLRAKGVKTPIMMVSAKSDEFDKVLALELGADDYLT
                     KPFSPRELLARVKAVLRRTKGEQEGDDSDNIADDSWLFGTLKVYPERHEVYKANKLLS
                     LTPKEFELLLYLMKHPNMTLTRERLLERIWGYDFGQETRLVDVHIGKLREKIEDNPKA
                     PQFIRTIRGYGYKFKEL"
     gene            complement(36649..37134)
                     /locus_tag="VQ540_000775"
     CDS             complement(36649..37134)
                     /locus_tag="VQ540_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HET2544606.1"
                     /translation="MAPTDKEDLIRTLELAPHVEGGYFRQTKKASDTINLAGKGRALY
                     TSIYFLLEETNPSHFHRLTADEIWYFHAGSPLTVHMITADGHYEAVTLGLDISKGQQL
                     HYCVPKGTIWGSTVDKDYALVSCLVAPGFEFEDFELFERVDLLATYPEHKEMIERLTR
                     Y"
     gene            37120..37347
                     /locus_tag="VQ540_000776"
                     /pseudo
     CDS             37120..37347
                     /locus_tag="VQ540_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
BASE COUNT        10951 a         7081 c         8056 g        11259 t
ORIGIN      
        1 aagtcagctc aaaacatggt tttgaggttg tagatgaaac tgacgaagtc agtaacaata
       61 cctacggtaa ggcgacgctg acgtggtttg aagagatttt cgaagagtat tagcgctaat
      121 ttttagggct ttcacctgac ttttaaagac tggcaaactt ttctgatgat tttcatgaag
      181 agcctgcgct tttatggtaa aatagtaaca gaataaaaga ggagagaaat aatgaaacgt
      241 agtatgtatg ctggtcgtgt tcgtgaggaa cacatcggac aagaaataac cttgaaagga
      301 tgggttggcc gtcgtcgtga ccttggtggt ttgatcttta tcgatcttcg tgaccgtgaa
      361 ggaatcatgc agttggttat caaccctgaa aaagtatctg cagaggttat ggcaacagct
      421 gaaagccttc gtagcgaatt tgttattgag gtgactggtc aggtcgctgc gcgtgagcaa
      481 gccaatgata agttgccaac tggtgcggtt gagttaaacg tgacagctct tattgtgctt
      541 aacacagcta agacaacacc atttgagatt aaggatggca ttgaggcaaa tgacgataca
      601 cgtttgcgtt accgttacct tgaccttcgt cgtccagaaa tgttggaaaa tcttaaactt
      661 cgtgccaagg tgacccactc tatccgcaac tatttggatg agttggagtt tatcgacgtg
      721 gagacaccat tcctttctaa gtcaacgcct gaaggggcgc gtgattattt agtgccgtct
      781 cgtgttaata aggggcattt ttacgctctt cctcaaagtc cacaaatcac gaaacagctc
      841 ttgatgaatg ctggttttga ccgttactac caaatcgtta aatgtttccg tgacgaggac
      901 ttgcgtggag accgccagcc tgaatttact caggtcgact tggaaacgtc cttccttact
      961 gagaaagaaa tccaagatat tacagaaggc ttgatcgcgc gcgtgatgaa ggaaacaaaa
     1021 ggcatcgaag taacgctacc gttccctcgt atgaaatacg atgatgctat ggctctttac
     1081 ggttctgaca agccagatac tcgttttgac atgttgcttc aggacttgac agaagtggtc
     1141 aaaggtgtag actttaaagt cttttcagaa gcacctgctg taaaagcgat tgtggtcaaa
     1201 ggagctgcgg acaactattc acgtaaagac atcgacaaga tgacggaagt agccaaacag
     1261 tatggtgcca aaggtcttgc ttgggtcaag gtggttgatg gagaattaaa cggaccagtt
     1321 gccaagttct tgactggtat ccaagaagaa ttgacaacag cgcttgctct tgaagataag
     1381 gacttggttc tctttgtggc ggatacgctt gaagtggtta atgcaacact gggtaccctt
     1441 cgtggacgta ttgctaaaga gcttggcttg attgataatg ataagttcaa cttcctttgg
     1501 gtggttgact ggccgatgtt tgaatggtct gaagaagaag gccgctacat gagcgcccac
     1561 catccattca cacttccaca ggaagagact gctcacgaat tagaaggtga tttggctaag
     1621 gttcgtgcca ttgcttacga tatcgtcttg aacggttatg agcttggtgg tggtagcctt
     1681 cgtatcaacc aaaaagacct tcaagaacgc atgttcaagg ctcttggttt ctcaactgaa
     1741 gaagccaatg accagtttgg tttccttctt gaagccatgg actatggttt cccaccgcac
     1801 ggtggtttgg ctatcgggct tgaccgtttt gtcatgttgc ttgctggaga agaaaatatc
     1861 cgtgaagtca ttgcctttcc taagaacaac aaggcaactg acccaatgac acaagctcca
     1921 tcaacagtcg ctctcaaaca actagaggaa ctcagcttac aagtagaaga agatgaaaca
     1981 aacaaaacga attaagcggt ggcgctatta tctgcgccgc tttgcttatc agataaaaat
     2041 tttacgtgtc ttacaaagta tctctcgaga aaagtatgat gagaagattt cggcctctct
     2101 ggtctatggt tttttatcag cagtagcagt taatttcttt ttccaaccag ggcatgtgta
     2161 ttcgagtggt gcaacaggtc tggcacagat tatctctgcc ttgagtaatc actggtttgg
     2221 ttttcatatt ccgatttcgc taagcttcta cgccattaac ttccctttga tggtcttagc
     2281 ttggtatcag attggccata agttcaccgt ctttaccttt atcacggtat ctatgagttc
     2341 cttctttatc cagtttgtcc ctgtggcaac cttgacggag gatcccatta tcaattccct
     2401 ttttgggggt gttgttatgg gtttggggat tggttttgct cttcgaaaca atatctccag
     2461 tggtgggacg gatatcgtca gcctgactat tcgtaagaaa acgggtaaga atgtcggtag
     2521 tatttctttc ttggtaaatg gaactatcat gctgatagca ggtttgacct ttggttggaa
     2581 atacgctctt tattctatga ttaccatctt tgtctctagc cgtgtgacag acgcagtctt
     2641 tactaagcaa aagcgtatgc aggccatgat tgtgacaaat catccagaga aggtaattga
     2701 aaaaatccat aaaaaattgc accgcggagc aaccatgatc cacgatgcag aaggaaccta
     2761 taatcacgag agaaaggcag ttttaatcac tgtcattaca cgtgcagagt ttaatgaatt
     2821 taaacagatt atgacacaag tggatccaag ctcctttgtc tctgtctcgg aaaatgttca
     2881 tattctagga agatttgttg agatagataa ttagtgatta atactcttcg aaaatctctt
     2941 caaaccacgt cagcttcacc ttgccgtata tatgttactg acttcgtcag ttctatctgc
     3001 aacctcaaaa ccatgttttg agctgacttc gtcagtttca tctacaacct caaaaccatg
     3061 ttttgagcaa cctgcggcta gcttcctagt ttgcactttg attttcattg agtataaaaa
     3121 gatcttggga aaagactcaa tttcagtaga aaaggaagta aatcttccca cattaaaacg
     3181 catagtatca agttttttca atacctgata gtatgcgttt ttgcttttaa cgactttttg
     3241 cccagtctct tatttttcga taattttgtg ggcgatcaat tgacggtaac aaatttgttt
     3301 attgttttta ttatcattaa taatctggag aatagtttca agggaaacac gaccaagctc
     3361 taaactattg atatcgacat aggctgccaa gttgagcttg ggattaaccg agtcaaagct
     3421 gagaacaggg acatccagct ggtgtttggc aatatagtta caaacgcctt cagctaggag
     3481 gctatcggtt gtgatgatag catcaatttg tggatcgtgc ttgaataatc gcttgctaaa
     3541 tttatagccc ttttcttcca gaaactcgtc ggcaaagtag atgcgattgt tgtcagtggt
     3601 aagtttgtaa tgtttaagcg cctgttcata gcctgttaaa cggtctttgg tcacgaagag
     3661 ctttttactt cctccgataa aggcaatgcg tttgcagcct tttttgatga aatattcagt
     3721 cgcatcaaaa ccagcttgaa cattgtcgtt gtcgacaagt gggatgaaag gagatagaga
     3781 tttacctaag ataaggaagg ggaactgttc ttctgcgacg agttttacga gagggtcttc
     3841 ttcttgggca tagagaaaga ttagcccatc tacacgcttg ccgtagacca tttgtgaaat
     3901 agcgttgaga cgctccttct catctttccc tgttgctatc tgaatggcat agtggttttc
     3961 agatgcgact tgagagatgc cacgtagaac cgatggaaag aaaggattct ggtagaaggc
     4021 gtctgagtca tcaggaagaa ctaatccgat aacctgagta tagctgctta ccaagctacg
     4081 agcgttgagg tttgggtggt agttgagttc cttcatagct ttgcgaacgc gtttttttgt
     4141 ttcgtcgcta atggttgatt tattttgaat aacacgggtt acggttgaag gcgaaacacc
     4201 agcagccttg gccacgtctt taatcgtaac gggcataaaa atctcctatt tatggtaatt
     4261 tggatcacgg aaatgtgttt tataaaagat agtgaccaga tacagaacaa aaagaatatt
     4321 ttgtacagta atcagggttg tcatattttg gccaaataat cccaaaataa gtgtaatcag
     4381 agtcggcaat cctaaacagt tcaagataaa gtgatagcac tctttaaagg ttctaaatga
     4441 aaagaggcgt gatttcttag tgatataaag gagaagacta gctcctagag agacgataaa
     4501 gaaattcaaa ccaaagagga agctcgcacc gagaactagg aagaggctga tatagatacg
     4561 attttgttgg taccagtctt tagaaattgc ttgggtcaag ctgtctttgc ttttgaaact
     4621 ctcagtctga atggctcggt aagagatgcg ggtcagttcc ttgctttcct tgctgatgac
     4681 tagttcattt gtatcgaaat gcagttgcaa gtccttaggt aattccttga tttgacttgg
     4741 accaatcaca acagaagggg cttgactagc tgttccagta taagttaatg tgccatcgac
     4801 aattgtagca tgttcagaga gatcctggac aacctcattt gtcagaggtt catagacatt
     4861 atcgataaaa gtttctagcg gataggtctc ctgggagctg ttttggatag caatgggtac
     4921 catagacaag ctgataagga agatactggt aaagagaagt tgaaaccagt tgagctcgaa
     4981 acgtttggac aggggcttac gaaaccccca aatacttgaa aaataggaaa atggatatgg
     5041 aagcataggt atctttctaa aaggtgtttt ctatatgagt attattatat agagaaatgc
     5101 gctttatttc aagtctagga gaaaaattgc ttgctacaag gatattattt acagtgacaa
     5161 ttgctaataa tcaatgaaaa tcaaagtgca aaccaggaag ctagctgcag gttgctcaaa
     5221 gcacaacttt gaggttggag ataaagctga cgtggtttga agagattttc gaagagtata
     5281 aaatgaaaaa gggtggcggg gataaattat cccttgtcgc caccacttgt aagtcctgaa
     5341 acaaagttct tttgtagaaa gaagaagaga atacagattg gaagggcgat gaggatagca
     5401 cctgctgaga agtaggcaat cttcaagttt ttcgcattgt taacgaaggt ttggagacct
     5461 acggcaacag taaagtattc tttctcacga agcaagaaac tagagaggat gtagtccccg
     5521 aaaggtccca tgaaggccca gagagcttgt acggcaacca ttgggcgaac aagtggtaga
     5581 acaatttgcc agaagcggcg gaagtgtcct gcaccgtcta gttttgcaga ttcgtctaaa
     5641 gacattggca ctgtatcgaa gtagcctttc atgagccaag cattcatcgg gataccacca
     5701 ccaacgtaga ggaagatgag gaaccagttg tggttaaggg cgttcaacat aagcgccata
     5761 acgaagaagg ctgtcaaagc ggccatagtt ggcaccattt ggatgatcaa gaagaagacc
     5821 aaactttgtt tacgagccaa gaagttgtaa cggctgtaag cataaccagc aagtacgatg
     5881 atacttgttt gaacagccat ggtaattaag gcgataatca aagtgttgag gtaccaagta
     5941 ccgtacaagg tttcagtgaa gaggccttta aagttatcaa aattgaggtc gatattagta
     6001 tctagtttaa aggctgagac gttacctgct ttaaaggctg acataatggt aatcaacagt
     6061 ggatagataa ttacaattga tagaccaatc aggtaaaggt aagtaaggct ttgagtcagt
     6121 ctacgtttga gtttaattga gttattcatc ttagacgtcc tccatatcaa atgcgtgtag
     6181 tttcttgaat gcgatcatag agattgagat gacaatgata gagataatca aggtaacagc
     6241 tgccgccatt gagtattgag gagatgtacc tgttgtcaaa cggtagatcc atgagatcaa
     6301 gatatcggtt gaaccagctc cacctccgac actaccaggt cctccaccat tgaagaggta
     6361 catgatagag aagttgttaa agttgaaggt gtattggcta atcaaagtag gtgccgcaac
     6421 agccaaaatc attgggaaag tgatgttgcg gaatttttgc caagcgttgg caccgtcaat
     6481 ataagctgct tcgtaaaggt cgttaggaat agattgcaag atacccaaag tcaaaacgta
     6541 gatgtatggg aatccgagcc aaccttgcat cataatcaag gcaatcttag tccaagttgg
     6601 gtctgttttc caaggaataa gagctccatc aaggaaagga aggaatttag ccaagattgg
     6661 caatacttga gtgttgatag caccgacact atcgttaaac atgtttgaga atgtcaagat
     6721 agtgatgaag gctgggacag cccaaggaag aaggaaaata acaccaaaga tacgttttcc
     6781 tttgataaat ggttggttgg caatgatagc tgtgaagata ccaattacga tttgtaaagt
     6841 agaagctgcc aaagcccaaa tgatagtcca agaaagaaca gaaccaaagg cagaacggaa
     6901 ggtactcaag ctccaaatgt ttgtaaagtt ggtcaaacca acccagtcca acaacttgtt
     6961 tggtggcaag tgttggaagt cgtagttggt aaaggcgatc atcaaggtta cgataactgg
     7021 gaagataatc gcgaaggtca tggcaacata agatggaatg atcaagaggt aagggaagcc
     7081 attttcataa atccctttga tcatgtcttt gagtgtgcgt ggaactggaa ttccattgtt
     7141 aatgcgtttt gcaatcgtat gtgcatcttt gatatttgag aaataaaaga gtacataaac
     7201 gattacaaag attagatgga aggcaccacg aatcagcata aagagggaat tatcacgacc
     7261 tggtttgtta ccaagagtga tgaggttgct caattcaggg gttgcaagtg ctaggaagta
     7321 aaggacaaat acgatggtta caccaaggaa gataaaacct ttggcttttt gtttattgta
     7381 aatctgtcct aacccaggaa tgatagacag cagggctgct ttactaggtt gttgcttttc
     7441 catattaact cctttcatag gatactactt ttttataaga aagctaaatt atttgtgtct
     7501 ctattgataa attcaaaggg ggatttgatt tccacccccc ttgaacaaat tttttattca
     7561 ccaaattttt gtttgattgt ttctttgatc aatgttacag catcgttagc agctgtttta
     7621 gcatcttttt gaccacttac agcatcaaag agcatatttt tcgctggatc ccaaactgca
     7681 gacatttgag agatgtttgg cagtggttga gtgttcttga actgtttgat aacagctgtt
     7741 gtcaactcat cgtttttacc ttcagcgtat gaacgagcct cagtattagc tgggatttcg
     7801 ttagtcttat catataatac tttttgttgt tcagttgcaa caaggaagtc tacaaatttt
     7861 tgagaagctt caaggttctt aacggcttga ggaatgaccc aagctttacc accaccgaat
     7921 gcagcatatt cttttccatt tggaagagtt gggatagttg caactccgta gtttacttta
     7981 gcatctttaa aggcttgagc tttccaaggt ccgtcgatga tagcagctgt tttaccttct
     8041 tggaattgag tttggattaa gtttccagca ccttctgtat cttgcatacc tttaggccat
     8101 ttttcgtacc aagatttagc gtaattgata cctacgatag aaccgtcgtt tgcaagaccg
     8161 atgtctttag cgtctttacc gttttggcca aagacgtaag caccgttacc ggcaagaagt
     8221 ccatatgtat agtagaagtt tgtccagtca gctaggaagg cagtagtttt accatcttca
     8281 ccagcgaatg cgtatttgct atctttagca aggttttcca agtcagcaaa tgtttttgga
     8341 gcatctttca ccaagtcttt gttgtagtac ataacaagtg actcgataac ggcaggagca
     8401 ccgtaaactt taccattagc agctgttaca agagatttag ttgtgtcgtc tgttttagca
     8461 ccatcgctca atttcacttc tgaaagttgt ccgtcagaac caaggctacc tacacggtcg
     8521 tatggagcca tcataacatc agggacatta ccagattggt tgtcaagaga aagtttatca
     8581 agacctccta gagcatcacc agttttaaga gtgactttta ctccagcttc tttttcataa
     8641 gctttagcaa cctcttcaat atagctctta tatccctcgt ctacatatac agtgagttct
     8701 ttgacttcag atgaaccaga atcagcaggc ttatcagcag ttttgcttcc gcaagctacc
     8761 aaaagcaagc tagcaagtgt agcagttcca agcaccgcag tgctcttcat aaatttagat
     8821 gacatagtgt attcctccta aagaatagca agttttattg ataaggaaac gcaaacgttt
     8881 tcctttatga gcttagtata gcacaaatag aaaacggttg caagtatttt ttgtaaaaat
     8941 tttaaaaaat ttttaagctt gatttgatag cataattttg cattttaata gaagaaaagt
     9001 atgaaataga taagaataca gtatttttaa taaaaatata tggaatctgt ctaaagaggg
     9061 aaatcaggag gggctacctc cctgtttcta atctatatct attttctata gacgtttgtg
     9121 ctttgttaca tataaattca agctccctaa ggaggtttta tactttgtag actgtctcgt
     9181 gagagtcaaa ccttaggatt agatagtttt aagttatctt tgctaaaatg agttagtttc
     9241 cttaaaaata atcaaaaaag ttttttaaaa acgcttgcaa ttatgcttga aaaggagtat
     9301 acttataagt aacgcaaacg tttgcgtctg caaaatacgc aacgttccat tattttaaca
     9361 cacgaggtgc tattatgaaa aaacgtcaaa gtggtgtgtt gatgcacatc tcttctcttc
     9421 caggagctta cggaatcgga tcatttggtc aaagtgctta cgacttcgtt gatttcttgg
     9481 tccgtacaaa acaacgttac tggcaaatcc ttccattagg agcaactagt tacggggatt
     9541 ctccttacca atctttctca gccttcgcag gaaacactca ttttatcgat ttagatatct
     9601 tggtggagca aggtttgttg gaagcaagtg accttgaagg agttgacttt ggtagcgatg
     9661 cgtctgaagt tgactatgct aaaatctact atgcacgtcg tcctctttta gaaaaagcgg
     9721 tgaaacgttt ctttgaagtc ggagatgtta aagattttga gaaatttgct caagacaacc
     9781 aatcatggct tgagctcttt gctgagtata tggctatcaa agagtatttt gacaatcttg
     9841 cttggactga atggccagat gcagatgctc gtgctcgtaa agcttcagca cttgaaagct
     9901 atcgtgagca attggcagac aagttggttt accaccgtgt gactcaatac ttcttcttcc
     9961 aacaatggtt gaaattgaaa gcttacgcta acgacaacca catcgaaatc gttggggaca
    10021 tgccaatcta cgtagcggaa gattcaagtg atatgtgggc aaatccacat ctcttcaaaa
    10081 cagatgtcaa tggtaaggct acttgtatcg caggatgccc accagatgag ttttctgtaa
    10141 ctggtcagct ttggggtaac ccaatctatg actgggaagc aatggacaaa gacggctaca
    10201 aatggtggat tgaacgcttg cgtgaaagct tcaaaatcta cgatatcgtt cgtatcgacc
    10261 acttccgtgg cttcgaatct tactgggaaa tccctgctgg ttccgataca gcagcacctg
    10321 gtgagtgggt gaaaggtcca ggctacaagc tttttgcagc cgttaaggaa gaacttggtg
    10381 agctaaacat catcgcagaa gaccttggct tcatgacaga tgaagtgatc gaattgcgtg
    10441 aacgtactgg cttcccagga atgaagattc ttcaatttgc cttcaaccca gaagacgaaa
    10501 gcattgatag cccacacttg gcacctgcta actcagttat gtacacagga acacacgata
    10561 acaatacggt tcttggttgg taccgtaatg agattgatga tgcgactcgt gagtacatgg
    10621 ctcgttacac gaaccgtaaa gaatacgaaa cagtggtaca cgctatgctt cgtacagtat
    10681 tttcatcagt tagctttatg gcaattgcaa ctatgcaaga tttactagaa ttggatgagg
    10741 cagctcgtat gaacttccca tctacccttg gtggaaactg gtcttggcgt atgactgaag
    10801 atcaattgac accagctgtc gaggaaggtt tgcttgactt gacaacaatt tatcgccgaa
    10861 ttaatgaaaa tttggtagat ttaaagaaat aagacaataa tcaggagaca actaaacatg
    10921 ttatcactac aagaatttgt acaaaatcgt tacaataaaa ccattgcaga atgtagcaat
    10981 gaagagcttt accttgctct tcttaactac agcaagcttg caagcagcca aaaaccagtc
    11041 aacactggta agaaaaaagt ttactacatc tcagctgagt tcttgattgg taaactcttg
    11101 tcaaacaact tgattaacct tggtctttac gacgatgtta aaaaagaact tgcagctgca
    11161 ggtaaagact tgatcgaagt tgaagaagtt gaattggaac catctcttgg taatggtggt
    11221 ttgggacgtt tggctgcctg ctttatcgac tcaattgcta ctcttggttt gaatggtgac
    11281 ggtgttggtc ttaactacca ctttggtctt ttccaacaag ttcttaaaaa caaccaacaa
    11341 gaaacaattc caaatgcatg gttgacagag caaaactggt tggttcgctc aagccgtagc
    11401 taccaagtac catttgcaga ctttactttg acatcaactc tttacgatat tgatgttact
    11461 ggttatgaaa cagcgactaa aaaccgcttg cgtttgtttg acttggattc agttgattct
    11521 tctattatta aagatggtat caactttgac aagacagata tcgctcgcaa cttaactctc
    11581 ttcctttacc cagatgatag tgaccgtcaa ggtgaattgc tccgtatctt ccaacaatac
    11641 ttcatggttt caaacggtgc gcaattgatc atcgacgaag caatcgaaaa aggaagcaac
    11701 ttgcatgacc ttgctgacta cgcagttgtc caaatcaacg atactcaccc atcaatggtg
    11761 attcctgaat tgattcgtct tttgactgca cgtggtatcg atcttgacga agcaatctca
    11821 attgttcgta gcatgactgc ctacactaac cacacaatcc ttgctgaagc gcttgaaaaa
    11881 tggcctcttg aattcttgca agaagtggtt cctcacttgg taccaatcat cgaagaattg
    11941 gaccgtcgtg tgaaggcaga gtacaaagat ccagctgttc aaatcatcga tgagagcgga
    12001 cgtgttcaca tggctcacat ggatatccac tacggataca gtgttaacgg ggttgcagca
    12061 ctccatactg aaatcttgaa aaattctgag ttgaaagcct tctacgacct ttacccagaa
    12121 aagttcaaca acaaaacaaa cggtatcact ttccgtcgtt ggcttatgca tgctaaccca
    12181 agattgtctc actacttgga tgagattctt ggagatggtt ggcaccatga agcagatgag
    12241 cttgaaaaac tgttgtctta tgaagacaaa gcagctgtca aagaaaaatt ggaaagcatc
    12301 aaggctcaca acaaacgtaa attggctcgt cacttgaaag aacaccaagg tgtggaaatc
    12361 aatccaaatt ctatctttga tatccaaatc aaacgtcttc acgagtacaa acgccaacaa
    12421 atgaacgctt tgtacgtgat ccacaaatac cttgacatca aagctggtaa catccctgct
    12481 cgtccaatca caatcttctt tggtggtaaa gcagctccag cctacacaat cgctcaagat
    12541 atcattcact tgatcctttg catgtcagaa gttattgcta acgatccagc agtagctcca
    12601 cacttgcaag tagttatggt tgaaaactac aacgttactg cagcaagctt ccttatccca
    12661 gcatgtgata tctcagaaca aatctcactt gcttctaaag aagcttcagg tactggtaac
    12721 atgaaattca tgttgaacgg agctttgaca cttggtacta tggacggtgc taacgtggaa
    12781 atcgctgagt tggttggaga agaaaacatc tacatcttcg gtgaagattc agaaactgtt
    12841 atcgaccttt acgcaaaagc agcttacaaa tcaagcgaat tctacgctcg tgaagctatc
    12901 aaaccattgg ttgacttcat cgttagtgat gcagttcttg cagctggaaa caaagagcgc
    12961 ttggaacgtc tttacaatga attgatcaac aaagactggt tcatgactct tcttgacttg
    13021 gaagactaca tcaaagtcaa agagcaaatg cttgctgact acgaagaccg tgacgcatgg
    13081 ttggataaag tcatcgttaa catttctaaa gcaggattct tctcatctga ccgtacaatc
    13141 gctcagtata acgaagacat ctggcacttg aactaatact cttcgaaaat ctcttcaaac
    13201 cacgtcagct ttatctgcaa cctcaaagcg gtgctttgag caacctgcgg ttagcttcct
    13261 agtttactct ttgattttca ttgagtataa gatacaaatt tatactaata catcttgtaa
    13321 aaaagcgagt ttcgattgaa attcgctttt ttaatgatgt agatttgggt caatcttgtc
    13381 taaaaatagg gaaatcctag atacagtgaa ggctttaaat gctggttttt actgtcctca
    13441 gccttatatt ttttcgtagt tgattacctc atacctcttg tattcgctta cataaagtat
    13501 tataatataa ttgtaggaaa gaaggtgttt ttatgatata cacacttaaa ttggtgttgt
    13561 ttattacctt tcttgtaata agcttgttac ctgataagat ttttggaaaa aataaaaaaa
    13621 tttggaaaat agtttttgca atattgacgg cagtggcagc attgtcattt atgtactaag
    13681 ttattttaag aatgtaggga aataaaccct acattctttt tagttttttc tgttttctaa
    13741 attctattta tccaagcgct tcaacatttc ttgcttcttc gcttcaagtt ctgcacgctt
    13801 ttcttcgatt tcggcatgtt ttttctcgag ttcagaacaa cttgcaccat tgctaaattc
    13861 ttttcgccat caggagatag ggtgagtcga catgtctatt actcacccaa agcagtccta
    13921 caaagcagga attttctgtt acttttttgg aaatagtaac gtttatacag ctttgacact
    13981 tcgtatcaaa gcgccaaaca cactccgagg gatttacaga aagcagaaaa ggaatgatct
    14041 ggtataagat cattcctttt ctctcttttt ctttaagtaa ttatatacaa tgtacgacga
    14101 agtcgtcatt gcaatgctga tccaccacct aaaggaaact ttaaacaaca ttgataagat
    14161 aaagaatata aacaacgaaa atacgttata cccaattaat tttattgtat atctcatgat
    14221 taaaagttaa tccttccgtt gttaggaatg gcatcatttt tatcccataa ttgtgctaaa
    14281 taagtccccg gtgataataa atttatagca aattctaaag caacatcatt tacaaaccaa
    14341 ctacctagat atctagaaat tgctgaacga atagcacttt ttgctgcatg ttttcctttt
    14401 actttaatta gatttgcaag gcctgcagta gttcctccta atgctaaagc tattgcagta
    14461 tctaatagag cacccatttg attaactgta ataccttgcc aagctgctct aaatggagag
    14521 tatgtaggtg ggattgtata atcgccttgt aattgtcggt taattacttc tttgatccat
    14581 tgttgtgaga cgtctggatg aaaagattgg atttcgtttg caagtgtatt gatttgttct
    14641 tctgttagag aagtgacagg ttgaagttcc atatttgttt caatttgtga tacttgttca
    14701 gaagcgtata cagctgaaac acttggaatc gctgatacaa ttaacacaat tgacgtcaaa
    14761 aaaaccgaaa taaatttcat taatttgttc atgagctttt ctccttttta tttgtatctg
    14821 cttacatttt atcatatgct gttattatag tcaaaaaaat atgctattat gttaaaaaaa
    14881 tatttttcaa aatataaatg gacggattta ttttggattt tatttgttat tttgacctgc
    14941 ctctatattg gtaaccatga tttgtttact ctcaatcatc aagaattctc ttttcgtggt
    15001 agcgtttggg gtctggtact ggccttatat cacttactat tcattgataa gtttgttata
    15061 tcgaatcgaa aataaagatt agagctatgc ttgactgtgt acttttagga ttgattttgg
    15121 aggaagattt tgtctctatt atttattatt ttaaatttat ttattttgta taagatctat
    15181 tctttgaggc gggaaaaatc gaaatacttg atttatacgg cctatatcat atttggggta
    15241 aatgtagtat atggtattca atggttatta agagaactga tttcaactat ttccccttaa
    15301 tgtgtatgga aactataaca aaacgcataa gattaaggtt tgtgtacctg ttcttatgcg
    15361 tttttataat attgaagatt ttcggtaagt tttatacctt tgggaagtct agtttagaat
    15421 gctttcccaa ccaaaatctc tgcttcgatg gtaatctctg tcagttggct ccagtcaatc
    15481 ttgctctggt caacgtgaaa gaggagagga gtcatactga gtagggcttg gagttgttct
    15541 gctgtgatag tcttagtcag agaggcagtt tgactagata ggatggtaaa gtgttcctgg
    15601 aaatgctcct tgatatcttg gttagaatac tccttgtttg tcagctggtc ctgtactctt
    15661 tgacggattt ctttgaggtg attttcagtt gggataacct ttatcaagat accgtctttg
    15721 gataaaacgc gacgaaattc tccatagttg gcaggtgaga agatatcaag cagaatatcc
    15781 atgttagcgt cttttatagg aagtcgtgcc aagtcgccaa cgaaccaatt gactgcccag
    15841 ttgggttcac ttttagcagc gatttggact gaatctttgg agatgtcaaa ggcatagaaa
    15901 gttttttcag agtgactttc ttgtagtttg cgagaataga atccttcacc acaaccgata
    15961 tccaaaattg ttgtggtagt ttttgagctt gcaagcaagt cagatacagc atctaagata
    16021 gcttggtaaa agccggcttc taggatttgt tgacggtttt gaaaattttc cttgtcatag
    16081 ttagcagatt gcttgatttg aggtgctaga ttgacatagc caaatttcgc caagtcaaaa
    16141 gaatgacggt tgcagcactt gaaattagtc tctaacagag tcagattttc ttgacagata
    16201 ggacaggcaa aggcagtcgc agaagcaaaa cgctgaagtt tgggcttgag atttgtattc
    16261 atagtttaag tgtatcaaaa gaggcaaatg aaagcaactt taggaataag tagattcagt
    16321 agaaataaaa ctaattctcc aatttataga atgaaattgc ttttatatct aaattgctat
    16381 ataataatga taaggaggaa ataagtatgt taaaagaagt attaaccgtt gcaaaagttg
    16441 cgaaaaaatc ttcattattt ttgggtggtg tcgcatttgg tacccttggt ttgaaaatct
    16501 tagcaagtaa ggaagctaaa aaaggttatt ctaaagcttt ggctaaggct tacaagttga
    16561 aagacgagct agatgcatct gtttctgttg tgaagcaaca tggagacgat gtcttgcaag
    16621 atgccaaata tttgtacgag caagagaaaa aagaagagca attagatagc cttataggtg
    16681 aataatatgt cttttaaagt gctacataga ggataccaac atatccgact atcatcttct
    16741 ttttcactta ccttggatat tcaagactat cttcgttcct tggcgagaga tgaaaagggg
    16801 attgagtcta tccagtttta catggatcaa cagcacttta ctctacgcat aaaagaaggc
    16861 ttttctgtat tagataatgc agaagccttt ttaaaaagaa ttgataaagg gaaagtttct
    16921 gagttgatga ctcttcccat tcgtagagaa gagagtgctt attctattgt ttcaggtgca
    16981 gcggttaagc gtgtactttt tcgtagtttt gtgccgtatc ctattcgcta tatatggact
    17041 tgttatcagg ctttgggtta tattagagaa gcctatcaaa cactagcgcg taaggaacta
    17101 acgatggaag tcttggactg ttcggctatt ttattgtcct tgtttatgaa ccaatccaag
    17161 acagctagca atatcatgtt tatgcttgat ttggggaatc atttagatca gtggtccttg
    17221 aaaaaaactg caacagattt agaacagagt cttcttgcaa aagagagcga tgtattccta
    17281 gtacagggcg atacggttgt tagtatcaag agttccgatg ttcaaatagg agatgtcttg
    17341 atcttatctc aaggaaatga aattctgttt gatggacaag tagtttcagg tttaggtatg
    17401 gtcaacgaaa gttccttgac aggagagagt tttccagttg aaaaaagaga gtctgatttg
    17461 gtttgtgcaa atacagtatt agaaactgga gagttacgca ttcgtgtaac agataatcag
    17521 atgaacagcc gtattttaca gctgattgag ttgatgaaga aatctgaaga aaacaagaaa
    17581 acgaaacaac gctatttcat caagatggcg gataaagtcg tcaaatataa tttcttgggg
    17641 gctgggctga cttacctatt gacaggttct ttttctaagg ctatttcttt cctattggtc
    17701 gatttctcct gcgctttgaa aatctctact cctgtagctt atttgacagt tatcaaggaa
    17761 gggttgaacc gtgaaatggt gattaaggat ggagatgttc tggagaaata tctggaagtt
    17821 gatactttct tgtttgataa gacaggaaca atcacaacta gttatcctat agttgaaaag
    17881 gtgttacctt ttggagacta tagtgaggaa gatattctca gaatcagtgc ctgtcttgag
    17941 gaacacattt atcatcctat tgctaatgcc atcgtcaagc aagctgagat agagggaatt
    18001 gaacatgagg aaatgcatgg gaaactccaa tatatcgcaa gcaaggggat caaatctcat
    18061 atagatggcc aaccagttct tattgggaat tatgtcttga tgcaggatga gcagattcat
    18121 atcagttcag aacaaaatgc tttaattgaa gagtacaaga gtcactacaa tctcttattc
    18181 ttggcttatc aaaatgaatt gattggaatg ttctgcattc atactccttt gagaaaagaa
    18241 gcaaaaacag ccttggataa acttaaggca caggggaaaa aattgattct ggcaacagga
    18301 gacaccttga ttaggacaga ggaattagtc aaagatttgc cctttgatca ggtctataca
    18361 gacttgaaac ctgatgggaa atttgagtta gtagagaaac tgcagaaagc aggtcacact
    18421 attttgatgg ttggagatgg attgaatgac tcagcggctt taactctatc agatatcggt
    18481 gtggtgatga atgagagtgc agatatttct aagcagatga gtgatatctt attgttagat
    18541 aatcgtttgg atttcttcca agagttggat tcgttatcat catctttgca aacactcatc
    18601 aagaaaaata ttcaggatac cgttgtcgta aatagtagtt tgattggctt tggcttattt
    18661 aattggttca gtccttcaaa tctctctatc ttacataatc taacaacctt gcgcattgtc
    18721 ctgcgtagcc tgtctattaa aaatagatag atgagagtta ttaacagcaa aaaggagtta
    18781 cctttctcga ggttaactcc tttgtttata gataaatgtt gaatagttta gtaagtcaat
    18841 acaaagtatt ttttcttccc acgacggata acagtcagtt cattttctaa cttatcagcg
    18901 tcactcaaga catagtcaag gtcttggatg cggtcgccgt ttacgtagat ggctccgttt
    18961 tggacgtctt cacgggcttg gcgttttgag ttaactatac cagatgagac gagcagttcc
    19021 acgatattgt tgttttcgtc tgcctgtact tggtagtttg gcacaccacg aagtccttgt
    19081 ttgagctctt tgacagaaag gtttttgatg tttcctgcaa agagttgctc agtgatgtta
    19141 agtgcttctt tgtaggcttc ttctccgtga acaagtgtaa caacttcacg agccaagact
    19201 ttttgagcca agcgttcgtg tggcgctgct tcaaattgtt tacgaatatc ttcaatctca
    19261 tcaagtgaca agaaagtaaa gattttcaag aagcgaacag cgtcagcgtc catcacgttc
    19321 atccagaatt ggtacatttc gtatggagaa gtcttttcgg gattgagcca gacggcattt
    19381 ccttctgatt taccaaattt tttaccagtt gcatctgtga ttagtggaac agtgataacg
    19441 tgaccagtct tgtccgcctt acgacgaagc aattcggtac cagctgtcat atttccccac
    19501 tggtcagaac caccgatttg aagagtgaca ttatggtctt ggttaaggac gaagaagtcg
    19561 tacccttgca tgatttggta agcgaactca gtgtaagaaa ttcctgtttc gatccgtttt
    19621 ttaacagatt ccttactcat catgtagttg accgtgaagt actttccaat gtcacggagg
    19681 aagtcaatga agctgatgct gccaaaccag tcgtagttgt tgaccatgac agccttgttt
    19741 tcgccatttt caaagtcaag aaaacgagaa agttgtcctt ggatagactt gacccagcca
    19801 tctactgtgt cttttgtttg gagactacgt tcagcatctt tgaaggacgg atctccgatg
    19861 agacctgtag caccgccaac gagcgcataa ggtttgtgac ctgctagttg caagcgacga
    19921 cttgtcaaga ttgcgacaag gtggcctagg tgaaggctgt cagcagttgg atcgtagcca
    19981 gtataataag aaacttgacc ttcttctagg gctttacgca aagcttcttc atcagtcgtt
    20041 tgaaatatca aaccacgctc ttttagctca tcaaaaatgt gcatgtgtct tttctccttt
    20101 ttaaaattat tgtttctacc tattgtatca caaacttggg caatagccta gcagaatagg
    20161 gaagaaagtg gctattttat tgaaaatttc ccttttgtgg tataatagat aaagtgagga
    20221 aatccatgca aaatcaatta aatgaattaa aacgaaaaat gctggaattt ttccagcaaa
    20281 aacaaaaaaa taaaaaatca gctagacctg gcaagaaagg ttcaagtacc aaaaaatcta
    20341 aaaccttaga taagtcagcc attttcccag ctattttact gagtataaaa gccttattta
    20401 acttactctt tgtactcggt tttctaggag gaatgttggg agttgggatt gctttggggt
    20461 acggagtggc cttatttgac aaggttcggg tgcctcagac agaagaattg gtgaatcagg
    20521 tcaaggacat ctcttctatt tcagagatta cctattcgga cgggacggtg attgcttcca
    20581 tagagagtga tttgttgcgc acttctatct catctgagca aatttcggaa aatctgaaga
    20641 aggctatcat tgcgacagaa gatgaacact ttaaagaaca taagggtgta gtacccaagg
    20701 cggtgattcg tgcgaccttg gggaaatttg taggtttggg ttcctctagt gggggttcaa
    20761 ccttgaccca gcaactaatt aaacagcagg ttgttgggga tgcgccgacc ttggctcgta
    20821 aggcggcaga gattgtggat gctcttgcct tggaacgcgc catgaataaa gatgagattt
    20881 taacgaccta tctcaatgtg gctccctttg gccgaaataa taagggacag aatattgcag
    20941 gggctcggca agcagctgag ggaattttcg gtgtagatgc cagtcagttg actgttcctc
    21001 aagcagcatt tttagcagga cttccacaga gtcccattac ttactctcct tatgaaaata
    21061 ctggggagtt gaagagtgat gaagacctag aaattggctt aagacgggct aaggcagttc
    21121 tttacagtat gtatcgtaca ggtgcattaa gcaaagacga gtattctcag tacaaggatt
    21181 atgaccttaa acaggacttt ttaccatcgg gcacggttac aggaatttca cgagactatt
    21241 tatactttac aactttggca gaagctcaag aacgtatgta tgactatcta gctcagagag
    21301 acaatgtctc cgctaaggag ttgaaaaatg aggcaactca gaagttttat cgagatttgg
    21361 cagccaagga aattgaaaat ggtggttata agattactac taccatagat cagaaaattc
    21421 attctgccat gcaaagtgcg gttgctgatt atggctatct tttagacgat ggaacaggtc
    21481 gtgtagaagt agggaatgtc ttgatggata accaaacagg tgctattcta ggctttgtag
    21541 gtggtcgtaa ttatcaagaa aatcaaaata atcatgcctt tgatacaaaa cgttcgccag
    21601 cttctactac caagcccttg ctggcctacg gtattgctat tgaccagggc ttgatgggaa
    21661 gtgaaacgat tctatctaac tatccaacaa actttgctaa tggcaatccg attatgtatg
    21721 ctaatagcaa gggaacagga atgatgacct tgggagaagc tctgaactat tcatggaata
    21781 tccctgctta ctggacctat cgtatgctcc gtgaaaaggg tgttgatgtc aagggttata
    21841 tggaaaagat gggttacgag attcctgagt acggtattga gagcttgcca atgggtggtg
    21901 gtattgaagt cacagttgcc cagcatacca atggctatca gaccttagct aataatggag
    21961 tttatcatca gaagcatgtg atttcaaaga ttgaagcagc agatggtaga gtggtgtatg
    22021 agtatcagga taaaccggtt caagtctatt caaaagctac tgcgacgatt atgcagggat
    22081 tgctacgaga agttctatcc tctcgtgtga caacaacctt caagtctaac ctgacttctt
    22141 taaatcctac tctggctaat gcagattgga ttgggaagac tggtacaacc aaccaagacg
    22201 aaaatatgtg gctcatgctt tcgacaccta gattaaccct aggtggctgg attgggcatg
    22261 atgataatca ttcattgtca cgtagagcag gttattctaa taactctaat tacatggctc
    22321 atctggtaaa tgcgattcag caagcttccc caagcatttg ggggaacgag cgctttgctt
    22381 tagatcctag tgtagtgaaa tcggaagtct tgaaatcaac aggtcaaaaa ccagggaagg
    22441 tttctgttga aggaaaagag gtagaggtca caggttcgac tgttaccagc tattgggcta
    22501 ataagtcagg agcgccagcg acaagttatc gctttgctat tggcggaagt gatgcggatt
    22561 atcagaatgc ttggtctagt attgtgggga gtctaccaac tccatccagc tccagcagtt
    22621 caagtagtag ttctagcgat agcagtaact caagtactac acgaccttct tcttcaaggg
    22681 cgagacgata attctctaaa tgaagtggcc aatcaatgga ttgccacttt tttcctttcg
    22741 tgttacaata agggtatgaa tcagtatcag aaaaagattg ttaacggaaa aatttattcg
    22801 ctcctatccg gcttaatatg gggaatctgt ggaattttag gagagtactt ctttactcat
    22861 tatcaggtgt cttcgggctg gattacctct atgcgtttga cactggcagg gagtcttgta
    22921 ctcatttggt ctgcaataca attaaaatcg caagtgctag atatttggcg agacaagaaa
    22981 aattacctgc cctttttagc ctatgctatt ttggggattt tttcagttca gtattttttc
    23041 tatctctgtt tagaatactc aaatgctacg acagcaacta ttttacagtt tattagccct
    23101 gtctttatcc tcttttacaa tcgcttggtt tatcaaaaac gagcgtcaaa aagcgctgtt
    23161 ttctatgttt tggttgccat gctgggtgtt tgcttgatgg ctacaaaggg agatctctct
    23221 cagttatcca tgacgccgct agctcttata acaggtttgc tgagtgccat gggtgttatg
    23281 tttaatgtta tcttgcccca accttttgct aagcgttatg gttttgttcc tacggttggg
    23341 tgggggatga ttttggcagg tttgtttagc aatgtcctct cgccggttta tcagctttcc
    23401 tttactcttg atatttggag tatcttgatt tgcctcatta tcgctttctt tggaacggct
    23461 tttgcttttt tcatttccat gaaggctgtg tccttggttt ctcctttggt ggtttccgtt
    23521 atcagtgcca gtgaacctct ctcttctgct ctcttgagtg ttttgttctt aggattagta
    23581 gtggattggt ccctccttct agctatagcc ttgattattt tacccatgat atttttgtct
    23641 atagaagaag cgaaagaaag tagataaaaa gtcttttctt aattctaaaa gtgtgctata
    23701 ctagaatagt caataaaaca cggggagata gttgtgaaga gtatttttag gttgtatcgg
    23761 taggggcttg cttttaccga cagcacgttt tatctcacat ccctaaaaaa tcatacctaa
    23821 aaacagacaa aaaggtttca aatttgaggc cttttttggt agaataggta tcattataac
    23881 gaaccaggag gcacctatga ctgctacaaa aatgaacgct caagaaatta tccaatttat
    23941 cgccaatgct gaaaagaaaa ccagtgtcaa agtaaccttt gaggggcaac tcgcaactgc
    24001 tgtgcctagc tctgttgtca aactaggaaa tgtcctattc ggagactgga aggacgtggc
    24061 tccgcttctt gaaggtttgg tagaaaatca agattatgtt gtcgagcaag atgctcgtaa
    24121 ttctgcagtt cctttgctag ataagcgtgc tatcaacgct cgtatcgagc caggtgctat
    24181 tatccgtgac caggtggaaa ttggtgacaa tgctgttatc atgatgggag ctgttatcaa
    24241 tatcggtgct gaaatcggtg ctggaaccat gattgacatg ggtgccatcc ttggtggccg
    24301 tgctatcgtt ggaaaaaata gccacgttgg tgcaggtgca gttttggcag gtgtgattga
    24361 gccagctagt gctgaaccag tctgtgtcgg agacaatgtt cttatcgggg ctaatgcagt
    24421 ggttatcgaa ggagtccaaa tcggtagtgg ttcagttgtc gctgcaggag ctatcgttac
    24481 ccaagatgtc ccagaaaacg tggtagtagc aggtgttcca gctcgtatta tcaaagaaat
    24541 tgatgcccaa actcaacaaa aaacagcgct agaggatgcg cttcgtacct tgtaattgta
    24601 aaagtaaaaa agaggcggaa ccctttttcc agcctctttc tgctatatcg gaggacagat
    24661 agatgttaga tttgattcag actagacgag ctttacacca gattccagag attggcttgg
    24721 aggagttcaa gactcaggct tatttgctgg atgtgattga gaaattgact acgggcaagg
    24781 attttgttca aattcgtact tggcggacag ggattttggt ctacctgcag ggaagtcagc
    24841 cggagcgaac cattggttgg cggacagata ttgatggcct gcctatcgtc gaacaaacag
    24901 gtctaccttt tacttctcaa caccaaggtc gcatgcatgc ctgtggtcat gattttcata
    24961 tgaccattgc cttaggctgt cttgagcgcg cccttgagga gcaacccaag aataatctgc
    25021 tctttctatt tcagcctgct gaagaaaatg aagctggtgg tatgctcatg tatgaggacg
    25081 gtgcttttgg agattggttg ccaaaccaat tctatggtct ccatgttcgt ccagatttga
    25141 aagtcggcca gattgcgact aatactcata cactctttgc aggaacttgc gaggtgaaga
    25201 tccgtttcaa aggtaaaggt ggccacgcag cttttcctca tgaagccaat gacgccttgg
    25261 tggcggctag ttactttgtg acccaagtgc agtcagttgt tagccgcaat gtcaacccaa
    25321 tcgagggagc agtggtgacc ttcggcgttt ttcaagctgg aaccaccaac aatgtcatca
    25381 cagacacagc ttttttacat ggaactattc gtgccttgac acaggacatg agtctcttgg
    25441 tgcaaaagag ggtaaaaaca gttgcagaag gggttgcagc tgcctttgat atggaagtcg
    25501 aagtggaact caaacaaggt ggatacctac ctgttgagaa caatccagcc ttggcgcgtg
    25561 aactgatgga cttctttgac gagaaagacg gaatcgagtt gattgatatc gaacctgcta
    25621 tgacaggcga ggactttggt tatctccttt caaaggttga tggcgtgatg ttttggctag
    25681 gtatcgatag tccctacgct cttcatcacc ctcaaatgag tcctaaggaa gaagtcttag
    25741 ctattggggt ggctgcggtg tctagtttcc tgaaaaagaa ggcagcagaa tagagggctt
    25801 gtctatgaaa tcggaattac gcaagcaagt cttgcatgaa atgaaggcta tatctcaaga
    25861 gcaaaaacag gctatagacc aagctttaac cgagcgaatt ttacaacacc ccttttatca
    25921 agaagccaag gtcatcgcaa cctacctctc tttttctcat gagtttcaaa cgcgggaact
    25981 gattgagcag gcgctgaagg acggcaagaa ggttttgaca cctaagacct atcccaaggg
    26041 gcgcatggat tttgtggtct atgatccgca acagttggta aaaacttcct ttgccttact
    26101 ggagccacag ggagatttgg aagtagtgga tgcatctcag attgatttga ttcatgttcc
    26161 tggcctggct tttacgacgg atggatatcg gattggatat ggtggaggtt attatgaccg
    26221 ctatctggaa catttttctg gtcgtgcttt gagtacgata tatccttgtc aaattcagga
    26281 ctttatacct gaaaaccatg atattcctgt tcaggaggta ttaattgatg aaggaaatct
    26341 ttgatagacg ttaccctgtg acgagtttct tcctcttagt gacggccttg gtatttttac
    26401 taatgttggt cactgcaggc ggaaactttg acagggcaga tacattattt cgatttggag
    26461 ccatgtatgg gccagctatt cgcctctttc ccgagcaggt ttggcgtctc ttgtctgcca
    26521 tttttgttca tattgggtgg gaacatttca ttgttaatat gctttcactt tattatcttg
    26581 gaaggcaggt agaggagatt ttcggttcta agcagttttt ctttctctat cttttatcag
    26641 gaatgatggg caatctcttt gtttttgtat ttagtcctaa atccttagca gcaggcgcct
    26701 ctacctctct ttatgggcta tttgccgcga ttattgttct tcgctatgca actcgcaatc
    26761 cttatattca acagctaggg caatcctatc tgacactttt tgtagttaac attattggaa
    26821 gtgttctgat tccaggaatc agcctagcag gccatatcgg tggtgcagtt ggtggcgcat
    26881 ttctagcagt tatctttcca gttagaggag aaaaacggat gtataatacc agccagagat
    26941 taggagcggt agtcttgttc gtaggactcg ccattttgct tttctacaag ggaatgggaa
    27001 tgtgacgaag ttgaaagaaa atttgtgtaa tgaaaaaaga taaggcattt tttgaacctt
    27061 atctttttat tttattttat tccttctcag tcaattcttt tccaagttgg atgaggtaat
    27121 tcttcaaatc atctttgact tgtgggtgtt tgagggcgta gtcgatggat gttttcatga
    27181 agccaaactt gtctccgaca tcgtaacgag ccccattgaa ctcacgagca aatacacgtt
    27241 gtgttttatt gagggtgtcg attgcatctg tcagctgaat ttcatttcct gcacctggag
    27301 cttggttttc gaggatttgg aaaatttcag gcgtgaggag gtagcgtccg ataatagcaa
    27361 ggtcgctagg agcgtcctct ggagctggtt tttcaacaaa ggtttcaaca ctgtaaagac
    27421 catcttttcc ttcgccttgc ggagcaataa ccccgtaagc agatacttcg tcatgaggga
    27481 ctggcatgac agcgatagta gacgcgtggg tacgctcgta gtcatccatg agttgtttgg
    27541 taagtggaac agccttttcg tctgtgatat ccatcaagtc atcaccaagc ataacgacaa
    27601 aaggttcatt tccgacgaaa gccttagctt gcaaaacagc atctccgaga ccgcgtggat
    27661 gagtttggcg gataaaatgc agacgcatgt cagttgtttt atcaactagc ttcaaaagat
    27721 ctgttttccc tttttctttg aggttatatt ccaattcgaa gtttgaatca aagtggtcct
    27781 caatagaacg ttttgattta ccagtgacaa ctagaatatc ttcaatacct gatttgagag
    27841 cctcttccac gataaactgg atagttggtt tgtctacgat tggcaacatt tctttggcaa
    27901 gggccttggt tgctggtaaa aatcgagttc ctagtccagc agcagggatg actgcctttc
    27961 taacttttga tgtcataaaa atcctttcta tagagggtta agaccactca ttttctgctt
    28021 taaattcatt gttcatgatg tcataaatgg catctttgat attggttccg tgataaataa
    28081 cttggtaaat agcctgtgta atgggcatat agactccaag ttcttgggct agttcatagg
    28141 ctgctcgagt cgttgaaatt ccttcgatta ccatgcccat attagcttct atatcagcta
    28201 gggattctcc tcgtccgaga gcatctccag ctctccagtt acgagagtgg atggaagttc
    28261 ccgttacgat caaatctccc acaccagata agccgctata ggtcaatgga ctggccccga
    28321 gtgctacccc taggcgggtg atttctgcta aacctcgagc gatgatggct gccttagcat
    28381 tatcaccaaa tccaagacca tgtaaagctc cagcaccgac agcaataata tttttaagag
    28441 caccagcagt ttcaaccccg ataacatccg tattggtata aagtcggaag tagtgattac
    28501 taaatagctc ctgaacgtat tgagctgttt gtaaatcttt agaagcagca gtgattaaag
    28561 ttaggtcacg cacaatggtt tcttccgcat gactaggccc tgaaacaacg acaatatcac
    28621 tgcggagctg ttcaggaatt tcttcttcaa ggatagttga taatcgttta tggctatcag
    28681 gttctaatcc ctttgaagcg tgcatgatga tagccttatg gtccaaggtt tgtgcaactt
    28741 gttgggcaac aagtcgtgtc acttttgttg ggacaacaaa caaaatcgca tccacatctt
    28801 tcaatgtttc tgctaagtcg gtgtaggcaa tgatattttc atctagaacg acatctttaa
    28861 agtagtgctt gttagtatga taggtattaa tttcattgat ttgctcggga agatttcccc
    28921 aaatacgtac ctcgtgtcca ttgtcattta agacttgtga aagggcagtt ccccaagaac
    28981 caggccccaa gacggcgacg gtttgttttt ccatgatttc ctccttgata gagttctttc
    29041 cattattcta tcatattcta gaggattttg cacttgcatt actggggtat ggtggaaaaa
    29101 tacacaaaga ccgagatgaa gggataaact cttagtcttt agttaaagtg agaagaaatc
    29161 tgatagatag tttgattcag tatatgctat aaatagaggt aaacaactca ggaggttctt
    29221 gtaggttgcg agagtttggc gaaaaaatta aaagattacg tttggctaaa aaaatcagtc
    29281 gttcagaatt ttgtggtgat gagtctgaat taagtatccg tcaattaatt agaattgaaa
    29341 atggagaatc cagaccaaca ctaacaaagt taaaatatat cgctgaacgt ttgggggggg
    29401 tgaagattac aagttgatgc caagttatat agagttggat aaggaatacc tagaattgaa
    29461 gtatttcttg atgaggactc ctacatacga agatgaaact atcgcccaaa agaaagagag
    29521 tgtttttgct aagatttttg aagagtatta tgataggcta cctgaggaag aaagatttat
    29581 catcccaaat tattcatatc tagcactagc gaactacaca gttcaaaaat taccagaaaa
    29641 gctagttgaa atactgtcct tctggtgatt ttgcttaatt tctgatgttc gagacatgat
    29701 tgaggagatt tgtcttgatt ttttcctaaa aaagggcaga ctcctccctt ggtttgatgc
    29761 tcgattttta aaataaggtg acttattctg ttaggcatgt tttcccctgc cctctagctc
    29821 tatatggaac agggagtatc agatttatct ggcagattgt atcaaataag gcttgaaact
    29881 gttttgaata ggcgtataga cttgagaatt tgagaatatg tcgtctagca gtagagacat
    29941 attttccggc aatatgaagg aagagacgtc gaaaacgctt gatagtcaag gactttactt
    30001 catcaccagc tagctgcttt aaaaagaggt agagattata agccagacag cccatcatca
    30061 tacgtacttc attcttaatc atggtcgaac tatctgtctt atccccaaag aatcctgctt
    30121 tcctttcttt gataaagttt tcagcattcc ctcgttcacg atagaattga aacagctcct
    30181 cactatctac actgcttaaa ttgttcaaat gaactttttt acaaccataa aaaagagcac
    30241 ttaatcgtac tcttctcttt taaggattag ttgaattaat tcaaatccac tagttctcct
    30301 gtttctaggt agactaggcg ttcacaaatg ttagcaatgt aatcagcgaa gcgttccaga
    30361 tgtcctatga tataaaggta ttgagttcca ttgggaattg aggtttcttg gtctttcata
    30421 agtccaatga tttcctttga taaggcataa taatattggt caatctgttc atctttttga
    30481 gcaatactaa tagcttttga ggcttggtgc aaaggaaagg caaccaataa atcggctagc
    30541 atgctgaggg ataatttacc catttggtgt aactgttctt cgtcaggggc tagttgattt
    30601 tcttttagtt gcaaaacagc tttggcaatg cctgccatat ggtctcccat acgttcaagg
    30661 tctgaacaag aagacatgat gctaatcaca aatcgaaggt cagacacttg tggctgttgc
    30721 aaggccaaca aacgggcaca ggtcaattcg atagcgcttt gaccttggtt gatagcatga
    30781 tccttattga taattagctc tgccatctcc ttgtctttgg aggctaaggc cagtaaggct
    30841 tttgaagctg tttcaaggac aagttgccct agtcctaaaa aggattgttc taattcatgc
    30901 aattctaagt caaattgatt tctcataggt ttttccttcc ttatccgaac cgtcctgaaa
    30961 tatagtcttc tgtgcgctga tcttttggat tggtaaacac gtcaacggta tctccaaatt
    31021 cgcaaatttc tcctgttaag aaaaaagcag ttttatctga aatacgtgaa gcttgttgca
    31081 tgttatgggt aacaatgata atcgtataat ccttttttag ttgctgaatg aggtcttcaa
    31141 tttttaaagt ggagataggg tctaaggctg aagtcggctc atccattaac agaacatcag
    31201 gttctactgc taaagctcgc gcaatgcaaa ggcgttgctg ctgaccgcca gataaggaca
    31261 tggcactctt tttaagatca tctttgactt cttcccaaat ggctgcccct tttaaagatt
    31321 tctccactaa ggcatctaat tgttttttgt ctcgaatacc atgtgtcctt ggaccataag
    31381 ccacgttatc atagatagac atggcaaagg gattaggctg ttgaaaaacc atccctacac
    31441 gcttgcgtag ctgattaagg ttgaatttgc tactataaat atcttgctca tctaagagga
    31501 cttggccttc aatatggcaa gaaggaacca aatcgttcat ccggttaagg gtttttagaa
    31561 aagttgattt gccacaacca gatgggccta tcaaggcagt aatctgtctt tctggtaatt
    31621 gaatcgaaat attttttaag gcttgaaaat ccccgtaaaa taagtctagg tgtctgactg
    31681 aaaatgttcc catactagga agctcctttc acaagttttc gagataataa gcttgataga
    31741 gtatttatca ttaaaacagt aataatcaaa atcacaccgg tagcataggc ttcattgaca
    31801 tgtagcccct cacttgacag catatacata tgcagggcta gagaacgacc tgaagacatg
    31861 agactacttg gcgtattggt agaggtacct aatgtataca tgagggcagc tgtctcacca
    31921 acgatacggc caatagctag tatcactcca gctaaaatac ctggcatggc aactggtaga
    31981 acaattctaa aaacagtccg taacttacct gccccaagtc cataacttgc ttgacgcatg
    32041 ctatcactaa cagataaaag ggcttcttct gttgagcgaa taatgactgg caacaccatg
    32101 atgactgagg ttaagattcc tgataacaga gagtattgaa aacctaagaa gactacaaag
    32161 aagagcatgc caaacagacc aaaaacaatg gaaggaatcc cagacaaggt atctgaggcc
    32221 aatcgcatga ttttaacaca aagggaatct ttttttgtat attccacaag ataaaaacca
    32281 gcaaaaatcc ctatgggcaa ggctaaaaga agagcaccaa agaccagaat aacggtggaa
    32341 ataatcgctg gcataaggga aatgttctca gaagtataag tccaagaaaa gagggataga
    32401 cttagatgag gtaagccttt gatgaggata aaaccaatga ttaaaaagag agagccaaag
    32461 gttaaagctg aaaaacaata aacgagaagt tttagcaggt atttactcat aagatgattt
    32521 tcctttcaag taggcaaagt aggcattaat caagagaata aggaaaaaga gaactgctga
    32581 ggttgcaata agggcttccc tatgctgacc tgatgcgtaa gccatttcca gaacaatatt
    32641 ggttgttaag gttctggttc ctgaaaagag tccacttgga ataatcggct ggttgcctgc
    32701 caccaaaata actgccatgg tttcacctac tgcgcgaccg attcctaaaa taactgctga
    32761 taaaatacca gatctcgcag ctggcaagat gacactaaaa atactccgtt catgactagc
    32821 tcctagagcc aagctaccag aataatacgt tttgggaact gttcggatag cagattctga
    32881 caaactgata atggttggca aaatcattat tcctaatagt aacgaagcgg ttaggacact
    32941 catgccattt cctaaaaagg ttctaatcca aggcaccaat aattgtaggc cgaaaaaacc
    33001 ataaacaata gatggaatgg ccgccatcaa gttgatagct gattttaaga agccatagac
    33061 gggctttgga caataataaa ccataaacac cgatgtcaag atgcctgttg gcaccccaat
    33121 cacaatcgct cctaaggtaa ttaataagga accaacgatc attggtaaaa taccatagct
    33181 tgccggaatg ttcgttggcg accaatcact gcctaataaa aaacgggcaa agccgtagtt
    33241 agccatgaaa ggtaagccat tactaaaaat aaagaaacag attagcaaaa tagctacaac
    33301 agctactgtt gcactcatga aaaaaattgc cctaaaaact gcttctttga aggcttgttt
    33361 tgtcacatct tgtcctttct agtgaagaaa gtaagggaga tacgacacct ccctacttgc
    33421 cttctttatc ttattgtacg atgaaacgtc tgcatctctt tagagattta tggagcaaac
    33481 attttattta atcttgtccc aggtggttaa tttgccacta aaaacgtctg caagttcagc
    33541 catactgact tggcttgcct tattgtcatt attgaccaca acagcaatac cgtctaaagc
    33601 aatagcatca tgggtgagac tcttaccttc ttcaggagtt aattccctag aaaccatacc
    33661 aatatcagcg gttttctcct taacagcggt aatacctgct gaagacccat tagaggtaat
    33721 atcaatcgta acttctggat tttctttttt ataagcttct gctaattttt ccattaaaga
    33781 agatactgaa gtggaaccta caacagacaa cttgcctgat aagtgttggc ttgtatattc
    33841 tgtggtttcg gttttagctt caataaattt attatctgtg accacttgtt gaccttgttt
    33901 ggagtggata aagctgataa aatcttgacc tagcttggaa agattagaag accaaacaat
    33961 gttgaaggga cgttgaagag ggtattcacc atctaaaact gtgtctcgac tagccttgac
    34021 accatcaatc tctaaagcct tgacagattt cgttaaagat cccaaggaga tgtagccgat
    34081 agcattagca ttcccttgaa ctgctgagag aacaccttct gtactatttt gaatcacagc
    34141 tgttttggca gtgttgtcaa tttttttatc accgtctttt ttgagaatcc ctgtgatttc
    34201 tgtgaaggca ccccgtgttc cagagccatt ttctcgtgaa atcacctcaa tcgttcctga
    34261 agctgactgt ttggaagcag ctgactgatt gccacaggca acaagcccaa atcctgataa
    34321 gccaatggct gcaagagtaa gcattttttt gaatttcata ataatcacct ttatctctat
    34381 gtatttttct tgtgtaggct tactacattt atagtctaac aagtctttgt aaaggtttat
    34441 ccctgattca tgtaaagatt gtgtaaagaa tcaaaaaaag ccacttttga aaaatggctg
    34501 ctcctaaaaa tagctttaaa aattattagt cctgtgcgaa agattggtta ggaagaaaaa
    34561 tcgtgaagca actgcctctg ccaagctgac tcgtcaccgt gacttggcca cctaataatt
    34621 gactgagttc tttgacaatg gcaaggccaa gaccagtgcc accagtttgt ctgcttcgac
    34681 ctttattaac tcggtaaaaa cgttcaaaaa tacgatcctg ctctaattga ctaataccaa
    34741 tccctgtatc tgatacagaa atcttaatgc cttcgttcac cttttgggtc ttgacctcaa
    34801 tttttccccc ttgttcagtg taacggatgg cattggataa aagattgagt aagatttggg
    34861 aaagtaattg actatctgat acgagggtga catcatctgg cacctgcacc tttagctgta
    34921 aatccttctt cttgagctga ggttgcaagc tttgagtcaa atcctgtaca aattctgcca
    34981 aagaaagggt cgtccattgt ataggcattt gttgagcctt agataaggta agaagatgct
    35041 caacaatatg ctcaagacgc aagctttctt tgtaaataat gtctagaaag tcatccttga
    35101 gcgcttcttc ttcagctgac atccccttaa tggtttcagc aaagccctta atcgaagtaa
    35161 ctggtgtcct caattcatgg gaggcatttg agacaaaggc taaatttaac ttttcataag
    35221 ttctaatcgt tgttaaatca tatagcaaga cgagcacagc ttccacagat tgggtggggc
    35281 taaaaacggg aactgctgtc acttctaaaa tcaagtcacc ctcatgaaac ccacttactt
    35341 cttgttttaa ccttgttttt tgatcaaagg cttggtgaac taaatttcga atatccatcc
    35401 gtttgaggtc atcaagtgaa cttatgtcgc cgtccacatc gggaaaataa tgaggcagag
    35461 agcgactgga taataacatc tgaccttgag cggaaactaa aaacgtcccc atggttaggt
    35521 gcgacagaag aacctccatt gtttcggcta ggtccttgta ttgctgatcc tgttgggaga
    35581 ctttggtttt tagggcagac acatactgag ccaaagactt taagtcttct tgcccttttt
    35641 ctaaaaagta ttcactactg gtcaagagag gttggtgcaa ggtctcaaaa gcaacttccc
    35701 atttccaaag gcaaaagagc cagtagccac cttgtcccaa agaaagggct agaagaaaga
    35761 gaccgatgcc tttactgatc caagttaatg ccatccctgc aatcagaatg aggctaacac
    35821 ttagattgac tagccaaaat tgaaggtagc gtttcatcta taactccttg aacttataac
    35881 cataaccccg aatggttcga ataaattgag gggctttagg attgtcttca attttttccc
    35941 tcaacttacc aatatgaacg tccaccaaac gtgtttcctg cccaaagtca tacccccaga
    36001 tacgttccaa aagacgctct ctagtcagtg tcatgttggg atgtttcata agatagagca
    36061 agagttcaaa ttcttttggg gtcaaactca gtaacttatt cgccttgtag acttcatgac
    36121 gctcagggta tactttcaag gtcccaaata gccaagaatc gtcagcgata ttatctgaat
    36181 catctccttc ttgttctcct ttagttcgcc tgaggacagc cttgacacgc gccagcaatt
    36241 ctctagggct aaaaggcttg gtcaggtagt catcagcccc taattccaag gccaaaacct
    36301 tatcaaattc atcacttttc gcagaaacca tcataattgg agttttgacg cctttggctc
    36361 tcagccgctt acaaacttcc atgccatcta attgtggtaa catgatatca agcaagataa
    36421 aatcaaaggg ttctgtttct gccaaagcta aggccttccg tccatttgtt accaattgag
    36481 tagaaaagcc ttccttactt aaatggtagt caagcaattt cagaatgtgt tcttcatcat
    36541 ccactaataa gacttgtttt gtcatctatt atctcctatt ggtaacatta taacacaatt
    36601 atcagaaatc ctaacattgc taaatcagat taaatttgct tatcaagact agtatctggt
    36661 caaacgctca atcatctcct tgtgctctgg ataggtcgcc agtagatcta ccctttcaaa
    36721 taattcaaaa tcctcaaatt caaaaccagg agcaacaaga caagaaacca gagcataatc
    36781 cttatcaact gttgatcccc aaatagtgcc cttaggaaca cagtagtgaa gttgttgccc
    36841 tttggatatg tccaggccta aagtgactgc ttcgtagtga ccatctgctg taatcatgtg
    36901 aacagtaagt ggggatcctg catgaaaata ccagatttca tctgctgtca atcggtgaaa
    36961 atgtgaagga ttcgtttctt ctaataagaa ataaatactg gtataaagcg cccttccctt
    37021 accagcaagg tttatagtgt ctgaagcttt ttttgtttgt ctaaaatagc caccttcaac
    37081 atggggagct aactctagag ttcttatcaa gtcttcttta tccgtcggag ccaatgggtt
    37141 gaagtaactc ttgttcaaag gtggtgttac gatttcaaga actcctctca gctctgagga
    37201 cacgataatg attgatgcga cggaagtaca aatcaatcgc cctaaaaaaa gaattagcga
    37261 attattctgg taaaaaaatg ccacgctatg aaggctcaag cgattgtcac aagtcaaggg
    37321 agaattgttt ctttggatat cgctgtg
//
LOCUS       DAVBDR010000015        34466 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.015, whole genome shotgun sequence.
ACCESSION   DAVBDR010000015 DAVBDR010000000
VERSION     DAVBDR010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 34466)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34466)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34466
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.015"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            143..361
                     /gene="infA"
                     /locus_tag="VQ540_000777"
     CDS             143..361
                     /gene="infA"
                     /locus_tag="VQ540_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HET2544607.1"
                     /translation="MAKDDVIEVEGKVVDTMPNAMFTVELENGHQILATVSGKIRKNY
                     IRILAGDRVTVEMSPYDLTRGRITYRFK"
     gene            386..502
                     /gene="rpmJ"
                     /locus_tag="VQ540_000778"
     CDS             386..502
                     /gene="rpmJ"
                     /locus_tag="VQ540_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HET2544608.1"
                     /translation="MKVRPSVKPICEYCKVIRRNGRVMVICPANPKHKQRQG"
     gene            520..885
                     /gene="rpsM"
                     /locus_tag="VQ540_000779"
     CDS             520..885
                     /gene="rpsM"
                     /locus_tag="VQ540_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HET2544609.1"
                     /translation="MARIAGVDIPNDKRVVISLTYVYGIGLATSKKILAAAGISEDVR
                     VRDLTSDQEDAIRREVDAIKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGKAVAIAGKKK"
     gene            903..1286
                     /gene="rpsK"
                     /locus_tag="VQ540_000780"
     CDS             903..1286
                     /gene="rpsK"
                     /locus_tag="VQ540_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HET2544610.1"
                     /translation="MAKPTRKRRVKKNIESGIAHIHATFNNTIVMITDVHGNAIAWSS
                     AGALGFKGSRKSTPFAAQMASEAAAKSAQEHGLKSVEVTVKGPGSGRESAIRALAAAG
                     LEVTAIRDVTPVPHNGARPPKRRRV"
     gene            1329..2264
                     /locus_tag="VQ540_000781"
     CDS             1329..2264
                     /locus_tag="VQ540_000781"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HET2544611.1"
                     /translation="MIEFEKPNITKIDENKDYGKFVIEPLERGYGTTLGNSLRRVLLA
                     SLPGAAVTSINIDGVLHEFDTVPGVREDVMQIILNIKGIAVKSYVEDEKIIELDVEGP
                     AEVTAGDILTDSDIEIVNPDHYLFTIGEGSSLKATMTVNSGRGYVPADENKKDNAPVG
                     TLAVDSIYTPVTKVNYQVEPARVGSNDGFDKLTLEILTNGTIIPEDALGLSARILTEH
                     LDLFTNLTEIAKSTEVMKEADTESDDRILDRTIEELDLSVRSYNCLKRAGINTVHDLT
                     EKSEAEMMKVRNLGRKSLEEVKLKLIDLGLGLKDK"
     gene            2276..2662
                     /gene="rplQ"
                     /locus_tag="VQ540_000782"
     CDS             2276..2662
                     /gene="rplQ"
                     /locus_tag="VQ540_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002887523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HET2544612.1"
                     /translation="MAYRKLGRTSSQRKAMLRDLTTDLLINESIVTTEARAKEIRKTV
                     EKMITLGKRGDLHARRQAAAFVRNEIASENYDEATDKYTSTTALQKLFSEIAPRYAER
                     NGGYTRILKTEPRRGDAAPMAIIELV"
     gene            2927..3193
                     /locus_tag="VQ540_000783"
     CDS             2927..3193
                     /locus_tag="VQ540_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002905356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HET2544613.1"
                     /translation="MKAIITVVGKDKSGIVAGVSGKIAELGLNIDDISQTVLDEYFTM
                     MAVVSSDEKQDFTYLRNEFEAFGQTLNVKINIQSAAIFEAMYNI"
     gene            3203..4540
                     /locus_tag="VQ540_000784"
     CDS             3203..4540
                     /locus_tag="VQ540_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PFL family protein"
                     /protein_id="HET2544614.1"
                     /translation="MDIRQVTETIAMIEEQNFDIRTITMGISLLDCIDPDINRAAEKI
                     YQKITTKAANLVAVGDEIAAELGIPIVNKRVSVTPISLIGAATDATDYVVLAKALDKA
                     AKEIGVDFIGGFSALVQKGYQKGDEILINSIPRALTETDKVCSSVNIGSTKSGINMTA
                     VADMGRIIKETANLSDMGAAKLVVFANAVEDNPFMAGAFHGVGEADVIINVGVSGPGV
                     VKRALEKVRGQSFDVVAETVKKTAFKITRIGQLVGQMASERLGVEFGIVDLSLAPTPA
                     IGDSVARVLEEMGLETVGTHGTTVALALLNDQVKKGGVMACNQVGGLSGAFIPVSEDE
                     GMIAAVQNGSLNLEKLEAMTAICSVGLDMIAIPEDTPAETIAAMIADEAAIGVINMKT
                     TAVRIIPKGREGDMIEFGGLLGTAPVMKVNGASSVDFISRGGQIPAPIHSFKN"
     gene            4784..5476
                     /locus_tag="VQ540_000785"
     CDS             4784..5476
                     /locus_tag="VQ540_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HET2544615.1"
                     /translation="MVKVRLYLVRHGKTMFNTIGRAQGWSDTPLTAEGERGIQELGIG
                     LRESDLQFERAYSSDSGRTIQTMGIILEELGLQGKIPYRMDKRIREWCFGSFDGAYDG
                     DLFMGIIPRIFNVDHVHQLSYAELAEGLVEVDTAGWAEGWEKLSGRIKEGFEMIAKEM
                     EDQGGGNALVVSHGMTIGTIVYLINGMHPHGLDNGSVTILEYEDGQFRVEVVGDRSYR
                     ELGCEKMEEGSI"
     gene            complement(5579..7224)
                     /locus_tag="VQ540_000786"
                     /pseudo
     CDS             complement(5579..7224)
                     /locus_tag="VQ540_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520796.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
     gene            complement(7214..7519)
                     /locus_tag="VQ540_000787"
                     /pseudo
     CDS             complement(7214..7519)
                     /locus_tag="VQ540_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809465.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TOBE domain-containing protein"
     gene            complement(7646..8305)
                     /locus_tag="VQ540_000788"
     CDS             complement(7646..8305)
                     /locus_tag="VQ540_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2544616.1"
                     /translation="MSEIEIINAKKIYHDVPVIENLNITIPKGSLFTLLGASGCGKTT
                     LLRMIAGFNSIEGGEFYFDDTKINNMEPSKRNIGMVFQNYAIFPHLTVRDNVAFGLMQ
                     KKVPKEELIQQTNKYLELMQIAQYADRKPDKLSGGQQQRVTLACALAVNPSVLLMDEP
                     LSNLEAKLRLDMRQAIREIQHEVGITTVYVTHDQEEAMAISDQIAVMKDGVIQQIGRP
                     K"
     gene            complement(8318..9439)
                     /locus_tag="VQ540_000789"
                     /pseudo
     CDS             complement(8318..9439)
                     /locus_tag="VQ540_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931989.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
     gene            complement(10027..10803)
                     /locus_tag="VQ540_000790"
     CDS             complement(10027..10803)
                     /locus_tag="VQ540_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000406168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HET2544617.1"
                     /translation="MEISKGIIFNIQHFSIHDGPGIRTTVFLKGCPLRCPWCSNPESQ
                     RMKPEKMKDAQREKFTLVGEEKTVEEIITEVLKDKEFYEESGGGLTLSGGEIFAQFEF
                     AKAILKSAKEHHIHTAIETTAFVDHEKFIDLIQYVDFIYTDLKHYNSIKHKKVTGVFN
                     QMIIKNIHYAFSQNKTIVLRIPVIPNFNNSLEDAEKFATLFNSLNIDQVQLLPFHQFG
                     ENKYRLLNRKYEMDGINALHPEDLIDYQKVFLNHHINCYF"
     gene            10925..11671
                     /locus_tag="VQ540_000791"
     CDS             10925..11671
                     /locus_tag="VQ540_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HET2544618.1"
                     /translation="MKRLEQIIKLVSEYEKIDVNTLSEKLNVSKVTIRKDLDKLESKG
                     LLHREHGYAVLNSGDDLNVRLSINYEIKRKIVQEAVKLVSDNETIMIESGSTCALLAE
                     EICKQKRNVTIVTNSFFIANFVRAYDSCRIIVLGGEFQKDSQVTVGPLLKEMIQTFHV
                     HQAFVGTDGYDKEMGFTGKDLMRSEVVQYISAASDKVIVLTDSSKFDKRGTVRRFALS
                     QVYEVITDEKLSKQNIATLENAGIMVKVVS"
     gene            11684..12664
                     /locus_tag="VQ540_000792"
     CDS             11684..12664
                     /locus_tag="VQ540_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001070834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HET2544619.1"
                     /translation="MNQDRNKLLSKIAYLYYIENLNQSQIAAKLGIYRTSISRMLTEA
                     RNAGIVKIEIENFDTNMFKLENYVKEKYGLESLEIIPNEFDDNPTILSERISQVAAGV
                     LRNLIDDNMKIGFSWGKSLSNLVDLIHSKSVRNVHFYPLAGGPSHIHAKYHVNTLIYE
                     MSRKFHGECTFMNATIVQENKLLADGILQSRYFENLKNSWKDLDIAVVGIGDFSNKGK
                     HQWLDMLTEDDFKELTKVKTVGEICCRFFDSKGKEVYENLQERTIAISLEDLKNIPQS
                     LAVAYGDTKVSSILSVLRANLVNHLITDKNTILKVLEEDGDLTFREILGE"
     gene            12859..13179
                     /locus_tag="VQ540_000793"
     CDS             12859..13179
                     /locus_tag="VQ540_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HET2544620.1"
                     /translation="MEIIVPDQIIMGLILYAGDAKQHIYKALDYIKNGTCERCEEEIQ
                     LADAALLEAHNLQTKFLAQEASGTKTEITALFVHSQDHLMTSMTEINLIKEIISLRKE
                     LHKK"
     gene            13225..13533
                     /locus_tag="VQ540_000794"
     CDS             13225..13533
                     /locus_tag="VQ540_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000238716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET2544621.1"
                     /translation="MVKIGLFCAAGFSTGMLVNNMKIAAQSSGVEAEIEAFSQSKLAD
                     YAPNIDVALLGPQVAYTLDKSKEICDKCDVPIAVIPMMDYGMLDGKKVLDLALSLISG
                     "
     gene            13550..14848
                     /locus_tag="VQ540_000795"
     CDS             13550..14848
                     /locus_tag="VQ540_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000041357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HET2544622.1"
                     /translation="MSKMDVQKIIAPMMKFVNMRGIIALKDGMLAILPLTVVGSLFLI
                     MGQLPFEGLNKSIASVFGANWTEPFMQVYSGTFAIMGLISCFSIAYSYAKNSGVEALP
                     AGVLSVSAFFILLRSSYIPKQGEAIGDAISKVWFGGQGIIGAIIIGLVVGSIYTFFIK
                     RKIVIKMPEQVPQAIAKQFEAMIPAFVIFLSSMIVYILAKSLTNGGTFIEMIYSAIQV
                     PLQGLTGSLYGAIGIAFFISFLWWFGVHGQSVVNGVVTALLLSNLDANKAMLASANLS
                     LENGAHIVTQQFLDSFLILSGSGITFGLVVAMLFAAKSKQYQTLGKVAAFPAIFNVNE
                     PVVFGFPIVMNPVMFVPFILVPVLAAVIVYGAIATGFMQPFSGVTLPWSTPAILSGFL
                     VGGWQGVITQLVILAMSTLVYFPFFKVQDRLAYQNEIKQS"
     gene            14999..17437
                     /locus_tag="VQ540_000796"
     CDS             14999..17437
                     /locus_tag="VQ540_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HET2544623.1"
                     /translation="MVNTEVARTTIKTEYFGSLTERMNKYREDVLNKKPYIDAERAVL
                     ATRAYERYKEQPNVLKRAYMLKEILENMTIYIEEESMIAGNQASSNKDAPIFPEYTLE
                     FVLNELDLFEKRDGDVFYITEETKEQLRSIAPFWENNNLRARAGALLPEEVSVYMETG
                     FFGMEGKMNSGDAHLAVNYQKLLQFGLRGFEERARKAKVALDLTDPASIDKYHFYDSI
                     FIVIDAIKVYAKRFVALAKSLAENANPKRKKELLEIADICSRVPYEPATTFAEAIQSV
                     WFIQCILQIESNGHSLSYGRFDQYMYPYMKADLESGKETEDSIVERLTNLWIKTITIN
                     KVRSQSHTFSSAGSPLYQNVTIGGQTRDKKDAVNPLSYLVLKSVAQTHLPQPNLTVRY
                     HAGLDARFMNECIEVMKLGFGMPAFNNDEIIIPSFIAKGVLEDDAYDYSAIGCVETAV
                     PGKWGYRCTGMSYMNFPKVLLITMNDGIDPASGKRFAPSFGHFKDMKNFSELENAWDK
                     TLRYLTRMSVIVENSIDLSLEREVPDILCSALTDDCIGRGKHLKEGGAVYDYISGLQV
                     GIANLSDSLAAIKKLVFEEERISPSQLWHALETDYAGEEGKVIQEMLIHDAPKYGNDD
                     DYADKLVTAAYDIYVDEIAKYPNTRYGRGPIGGIRYSGTSSISANVGQGRGTLATPDG
                     RNAGTPLAEGCSPSHNMDQHGPTSVLKSVSKLPTDEIVGGVLLNQKVNPQTLAKEEDK
                     LKLIALLRTFFNRLHGYHIQYNVVSRETLIDAQKHPEKHRDLIVRVAGYSAFFNVLSK
                     ATQDDIIGRTEHTL"
     gene            17456..18124
                     /locus_tag="VQ540_000797"
     CDS             17456..18124
                     /locus_tag="VQ540_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HET2544624.1"
                     /translation="MEFMLDTLNLDEIKKWSEILPLAGVTSNPTIAKREGSINFFERI
                     KDVRELIGSTPSIHVQVISQDFEGILKDAHEIRRQAGDDIFIKVPVTPAGLRAIKVLK
                     KEGYHITATAIYTVIQGLLAIEVGADYLAPYYNRMENLNIDSNSVIRQLALAIDRQNS
                     PSKILAASFKNVAQVNNALAAGAHAVTAGADVFESAFAMPSIQKAVDDFSDDWFVTQN
                     SRSI"
     gene            18142..19230
                     /locus_tag="VQ540_000798"
     CDS             18142..19230
                     /locus_tag="VQ540_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol dehydrogenase"
                     /protein_id="HET2544625.1"
                     /translation="MRIFASPSRYIQGENALFENAKSILDLGNYPILLCDQLVYDIVG
                     KRFEDYLHRYGFHIVLALFNGEASDNEINRVVALAEKENCDSIIGLGGGKTIDSAKAI
                     ADLIEKPVIIAPTIASTDAPVSALSVIYTDEGAFDHYLFYSKNPDLVLVDTKVISQAP
                     KRLLASGIADGLATWVEARAVMQANGKTMLGQQQTLAGVAIAKKCEETLFADGLQAMA
                     ACEAKVVTPALENIVEANTLLSGLGFESGGLAAAHAIHNGFTALTGDIHHLTHGEKVA
                     YGTLVQLLLENRPKEELDKYIEFYKKIGMPTTLKEMHLDQVGYDDLIKVGKQATMEGE
                     TIHQMPFKISPSDVAQAIIAVDAYVNSK"
     gene            19685..22186
                     /locus_tag="VQ540_000799"
     CDS             19685..22186
                     /locus_tag="VQ540_000799"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014639013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HET2544626.1"
                     /translation="MSFYNHKEIEPKWQGYWAEHHTFKTGTDASKPKFYALDMFPYPS
                     GAGLHVGHPEGYTATDILSRYKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTA
                     ENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVE
                     ELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLNDLDELDWSESIKD
                     MQRNWIGKSTGANVTFKVKGTDKEFTVFTTRPDTLFGATFTVLAPEHELVDAITSTEQ
                     AEAVADYKHQASLKSDLARTDLAKEKTGVWTGAYAINPVNGKEIPIWIADYVLASYGT
                     GAVMAVPAHDQRDWEFAKQFDLPIVEVLEGGNVEEAAYTEDGLHVNSDFLDGLNKEDA
                     IAKIVAWLEEKGCGQEKVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLV
                     LPVTKDIRPSGTGESPLANLTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPH
                     NTEKLADEDLLKQWLPVDIYVGGAEHAVLHLLYARFWHKFLYDLGVVPTKEPFQKLFN
                     QGMILGTSYRDHRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDV
                     VEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLIRSKEIVAENNGALD
                     KVYNETVKAVTEQIDSLKFNTAIAQLMVFVNAANKEDKLYVDYAKGFIQLIAPFAPHL
                     AEELWQTVAATGESISYVTWPTWDESKLVEDEIEIVVQIKGKVRAKLMVAKDLSREEL
                     QEIALADEKVKAEIDGKEIVKVISVPNKLVNIVVK"
     gene            22380..23075
                     /locus_tag="VQ540_000800"
     CDS             22380..23075
                     /locus_tag="VQ540_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001144916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2544627.1"
                     /translation="MPVNEYGQMIGESMEGYTPGELPSIDFLEGRYARIEALSVEKHA
                     EDLLAVYGPDTPQEMWTYLFQEPVADMGELVSLLHQMLARKDRFYYAIIDKATGKALG
                     SFSLMRIDQNNRVIEVGAVTFSPELRGTRIGTEAQYLLARYVFEELNYRRYEWKCDAL
                     NLPSRRAAERLSFIYEGTFRQAVVYKGRTRDTDWLSMIDKDWPQVKDRLETWLRPENF
                     DKNGQQYKSLREL"
     gene            23087..23503
                     /locus_tag="VQ540_000801"
     CDS             23087..23503
                     /locus_tag="VQ540_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2544628.1"
                     /translation="MITIKKQEIVKLEDVLHLYQAVGWTNYTHQPEMLEQALSHSLVI
                     YLALDGDAVVGLIRLVGDGFSSVLVQDLIVLPIYQRQGIGSALMKEALEDYKDAYQVQ
                     LVTEETERTLGFYRSMGFEILSTYNCIGMTWMNRKK"
     gene            complement(24130..24222)
                     /locus_tag="VQ540_000802"
     CDS             complement(24130..24222)
                     /locus_tag="VQ540_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HET2544629.1"
                     /translation="MMELVLKTIIGPIVVGVVLRIVDKWLNKDK"
     gene            24383..25354
                     /gene="ruvB"
                     /locus_tag="VQ540_000803"
     CDS             24383..25354
                     /gene="ruvB"
                     /locus_tag="VQ540_000803"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000502070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HET2544630.1"
                     /translation="MGDEELVERTLRPQYLREYIGQDKVKDQLQIFIEAAKMRDEALD
                     HVLLFGPPGLGKTTMAFVIANELGVNLKQTSGPVIEKAGDLVAILNELEPGDVLFIDE
                     IHRLPMSVEEVLYSAMEDFYIDIMIGAGEGSRSVHLELPPFTLIGATTRAGMLSNPLR
                     ARFGITGHMEYYAHADLTEIVERTADIFEMEITHEAASELALRSRGTPRIANRLLKRV
                     RDFAQIMGNGVIDDIITDKALTMLDVDHEGLDYVDQKILRTMIEMYSGGPVGLGTLSV
                     NIAEERETVEDMYEPYLIQKGFIMRTRSGRVATAKAYEHLGYEYSEK"
     gene            25335..25907
                     /locus_tag="VQ540_000804"
     CDS             25335..25907
                     /locus_tag="VQ540_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001098890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase family protein"
                     /protein_id="HET2544631.1"
                     /translation="MNTVKNKQEILEAFRENPDMMAILTIIRDLGLKDSWLAAGSVRN
                     FIWNLLSDKSPFDHETDIDVIFFDPDFSYEETLLLEKKLREDFPQYQWELKNQVYMHQ
                     HSPHTASYTSSRDAMSKYPERCTAVGLRLNEESDFELYAPYGLEDILNFQVRPTPHFL
                     ENEDRMELYQTRLSKKNWQEKWKNLIFKNT"
     gene            26138..26896
                     /locus_tag="VQ540_000805"
     CDS             26138..26896
                     /locus_tag="VQ540_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HET2544632.1"
                     /translation="MFGFFKKDKAVEVEVPTQVPAHIGIIMDGNGRWAKKRMQPRVFG
                     HKAGMEALQTVTKAANKLGVKVITVYAFSTENWTRPDQEVKFIMNLPVEFYDNYVPEL
                     HANNVKIQMIGETDRLPKQTFEALTKAEELTKNNTGLILNFALNYGGRAEITQALKLI
                     SQDVLDAKINPGDITEELIGNYLFTQHLPKDLRDPDLIIRTSGELRLSNFLPWQGAYS
                     ELYFTDTLWPDFDEAALQEAILAYNRRHRRFGGV"
     gene            26905..27708
                     /locus_tag="VQ540_000806"
     CDS             26905..27708
                     /locus_tag="VQ540_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HET2544633.1"
                     /translation="MTQDLQKRTLFAGIALAIFLPILMIGGLLLQIAIGIIAMLAMHE
                     LLKMRGLETMTMEGLLTLFATFALTIPLENYLTFLPVDGNVVAYSVLISIMLGTTVFS
                     KSYTIEDAVFPLAMSFYVGFGFNALLDARVAGLDKALLALCIVWATDSGAYLVGMNYG
                     KRKLAPRVSPNKTLEGALGGILGAILVTIIFMIVDSTVALPYGIYKMSVFAIFFSIAG
                     QFGDLLESSIKRHFGVKDSGKFIPGHGGVLDRFDSMLLVFPIMHLFGLF"
     gene            27730..28989
                     /gene="rseP"
                     /locus_tag="VQ540_000807"
     CDS             27730..28989
                     /gene="rseP"
                     /locus_tag="VQ540_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HET2544634.1"
                     /translation="MLGILTFILVFGIIVVVHEFGHFYFAKKSGILVREFAIGMGPKI
                     FAHIGKDGTAYTIRILPLGGYVRMAGWGDDTTEIKTGTPVSLTLADDGKVKRINLSGK
                     KLDQTALPMQVTQFDFEDKLFIKGLVLEEEKTFAVDHDATVVEADGTEVRIAPLDVQY
                     QNATIWGKLITNFAGPMNNFILGVVVFWVLIFMQGGVRDVDTNQFHIMPQGALAKVGV
                     PETAQITKIGSHEVSNWESLIQAVETETKDKTAPTLDVTISEKGSDKQVTVTPEDSQG
                     RYLLGVQPGVKSDFLSMFVGGFTTAADSALRILSALKNLIFQPDLNKLGGPVAIFKAS
                     SDAAKNGIENILYFLAMISINIGIFNLIPIPALDGGKIVLNILEAIRRKPLKQEIETY
                     VTLAGVVIMVVLMIAVTWNDIMRLFFR"
     gene            29002..30855
                     /locus_tag="VQ540_000808"
     CDS             29002..30855
                     /locus_tag="VQ540_000808"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HET2544635.1"
                     /translation="MKQSKMPIPTLREMPSDAQVISHALMLRAGYVRQVSAGVYSYLP
                     LANRVIEKAKNIMRQEFEKIGAVEMLAPALLSAELWRESGRYETYGEDLYKLKNREKS
                     DFILGPTHEETFTAIVRDSVKSYKQLPLNLYQIQPKYRDEKRPRNGLLRTREFIMKDA
                     YSFHANYDSLDSVYDEYKAAYERIFTRSGLDFKAIIGDGGAMGGKDSQEFMAITSART
                     DLDRWVVLDKSVASFDEIPAEVQEEIKAELLKWIVSGEDTIAYSSESSYAANLEMATN
                     EYKPSNRVVAEEEVTRVATPDVKSIDEVAAFLNVPEEQTIKTLFYIADGELVAALLVG
                     NDQLNEVKLKNHLGADFFDVASEEEVANVVQAGFGSLGPVGLPENIKIIADRKVQDVR
                     NAVVGANEDGYHLTGVNPGRDFTAEYVDIREVREGEISPDGQGVLNFARGIEIGHIFK
                     LGTRYSASMGADVLDENGRAVPIIMGCYGIGVSRLLSAVMEQHARLFVNKTPKGEYRY
                     AWGINFPKELAPFDVHLITVNVKDEEAQALTEKLEASLMGAGYEVLTDDRNERVGVKF
                     SDSDLIGLPIRITVGKKAADGIVEVKIKATGDTIEVHADNVLETLEILSKK"
     gene            30955..32334
                     /gene="bglA"
                     /locus_tag="VQ540_000809"
     CDS             30955..32334
                     /gene="bglA"
                     /locus_tag="VQ540_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000943526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HET2544636.1"
                     /translation="MLRFPKDFVWGSSTSGPQTEGRVAGDGKGDNLWDYWFQVEPNRY
                     YNGIGSDKTSTFYENWERDIELLLETGHTVFRTSIQWSRIFPQGCGKVNPQGVDFYRK
                     VFEAIKAKGIRLLVNLYHFDLPFALQEDGDGWENKATVSAYEDYARFCFETYGDLVDQ
                     WITFNEPIVPVEFGYFYDAHYPHKVDAEAAVKVAYHTQLASSRAVKACHELLPDSKIG
                     IVLNLTPAYPRSQHPADVKAARIAALFQAQSFLDPSVLGTYPQELVEILHEHGLLPDA
                     TEEELELIHDNTVDFLGVNYYQPLRVMAPRFAKHPESPLLPEHFYEPYVMPGRKINSH
                     RGWEIYEQGIYDIAQNIKENYGNIEWMLTENGMGVEGEEKFRQDGMIQDDYRIDFVKG
                     HLRELHRAIEDGANCKGYLIWTFIDCWSWLNSYKNRYGLVELDLETQERRLKKSGHWF
                     KKLSDNNGF"
     gene            32526..34334
                     /gene="glmS"
                     /locus_tag="VQ540_000810"
     CDS             32526..34334
                     /gene="glmS"
                     /locus_tag="VQ540_000810"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014621492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HET2544637.1"
                     /translation="MCGIVGVVGNTNATDILIQGLEKLEYRGYDSAGIFVLDGADNHL
                     VKAVGRIAELSAKTAGVEGTTGIGHTRWATHGKPTEDNAHPHRSETERFVLVHNGVIE
                     NYLEIKEEYLAGHHFKGQTDTEIAVHLIGKFAEEDGLSVLEAFKKALHIIRGSYAFAL
                     IDSENPDVIYVAKNKSPLLIGLGEGYNMVCSDAMAMIRETNQYMEIHDQELVIVKADS
                     VEVQDYDGNRRERASYTAELDLSDIGKGTYPYYMLKEIDEQPTVMRKLIQAYTDEAGQ
                     VVVDPDIIKAVQDADRIYILAAGTSYHAGFASKKMLEELTDTPVELGISSEWGYGMPL
                     LSKKPLFIFISQSGETADSRQVLVKANEMGIPSLTVTNVPGSTLSREANYTMLLHAGP
                     EIAVASTKAYTAQIAALAFLAKAVGEANGNAKAQAFDLVHELSIVAQSIESTLSEKET
                     IEAKVRELLETTRNAFYIGRGQDYYVAMEASLKLKEISYIQCEGFAAGELKHGTIALI
                     EEGTPVLALLSDPVLANHTRGNIQEVAARGAKVLTIAEENVAKDTDDIVLTTVHPYLS
                     PISMVVPTQLVAYFATLHRGLDVDKPRNLAKSVTVE"
BASE COUNT        10494 a         5881 c         7579 g        10512 t
ORIGIN      
        1 aaaaagtatt gacaaatttg aaataaagcg tttttcgcac ttgcaaaaat ccgctacaaa
       61 tgttatactg agatagtctg acttataatt gttgtctctg tgtctagagg catcgaatcg
      121 aaatttatgg aggtgctttt gcgtggcaaa agacgatgtg attgaagttg aaggcaaagt
      181 agttgataca atgccgaatg caatgtttac ggttgaactt gaaaatggac atcagatttt
      241 agcaacagtt tctggtaaaa ttcgtaaaaa ctatattcgt attttagcgg gagatcgtgt
      301 tactgtcgaa atgagtccat atgacttgac acgtggacgt atcacttacc gctttaaata
      361 atcgaaaaac ttggagggat aagaaatgaa agtaagacca tcggtcaaac caatttgcga
      421 atactgtaaa gttattcgtc gtaatggtcg tgttatggta atttgcccag caaatccaaa
      481 acacaaacaa cgtcaaggat aagatagaaa ggagaaaaca tggctcgtat tgctggagtt
      541 gatattccaa atgacaaacg cgtagtaatc tcattgactt atgtttatgg tatcggactt
      601 gcaacatcta agaaaatttt ggctgctgct ggaatctcag aagatgttcg tgtacgtgat
      661 cttacatcag atcaagaaga tgctatccgt cgtgaagtgg atgcaatcaa agttgaaggt
      721 gaccttcgtc gtgaagtaaa cttgaacatc aaacgtttga tggaaatcgg ttcataccgt
      781 ggtatccgtc accgtcgtgg acttcctgtc cgtggacaaa atactaaaaa caacgctcgc
      841 actcgtaaag gtaaagctgt tgcgattgct ggtaagaaaa aataatatag gaggtaaaag
      901 tcttggctaa accaacacgt aaacgtcgtg tgaaaaagaa tatcgaatct ggtattgctc
      961 atattcacgc tacatttaat aacactattg ttatgattac tgatgtgcat ggtaatgcaa
     1021 ttgcttggtc atcagctggt gctcttggtt tcaaaggttc tcgtaaatct acaccattcg
     1081 ctgctcaaat ggcttctgaa gctgctgcta aatctgcaca agaacacggt cttaaatcag
     1141 ttgaagttac tgtaaaaggt ccaggttctg gtcgtgagtc agctattcgt gcgcttgctg
     1201 ccgctggtct tgaagtaaca gcaattcgtg atgtgactcc agtgccacac aatggtgctc
     1261 gtcctccaaa acgtcgccgt gtataatcat cgcattacac tgcttttcgt ttaagaggga
     1321 gtaactaaat gatcgagttt gaaaaaccaa atataacaaa aattgatgaa aataaagatt
     1381 atggcaagtt tgtaatcgaa ccacttgaac gtggctacgg tacaactctt ggtaactctc
     1441 ttcgtcgtgt acttctagct tctctaccag gagcagctgt gacatctatc aacattgatg
     1501 gtgtgttaca tgagtttgac acagttccag gtgttcgtga agacgtgatg caaatcattc
     1561 tgaacattaa aggaattgca gtgaaatcgt acgttgaaga cgaaaaaatc atcgaactgg
     1621 atgttgaagg tcctgctgaa gtaacagctg gtgacatttt gacagatagc gatattgaaa
     1681 ttgtaaatcc agatcattat ctctttacaa ttggtgaagg ttcttctcta aaagcgacta
     1741 tgactgttaa cagtggtcgt ggatatgtac ctgctgatga aaataaaaag gataatgcac
     1801 cagttggaac acttgctgta gattctattt atacaccagt tacaaaagtc aactatcaag
     1861 tggaacctgc tcgtgtaggt agcaatgatg gtttcgacaa attaaccctt gaaatcttga
     1921 caaatggaac aattattcca gaagatgctt tagggctttc agcacgtatt ttgacagaac
     1981 atcttgattt gtttacaaat cttactgaga ttgctaagtc aactgaagtg atgaaagaag
     2041 ctgatactga atctgacgac cgtattttag atcgtacgat tgaggaactg gacttgtctg
     2101 tgcgttcata caactgttta aaacgtgccg gtatcaatac tgtgcatgat ttgacagaaa
     2161 aatctgaagc agagatgatg aaagtacgaa atcttggacg caagagtttg gaagaagtga
     2221 aactcaaact cattgatttg ggtcttggat taaaagataa ataaaggagg aatacatggc
     2281 ttaccgtaaa ctaggacgca ctagctcaca acgtaaagca atgcttcgcg atttgacaac
     2341 tgaccttttg atcaacgaat caatcgtgac aactgaagct cgtgctaaag aaatccgtaa
     2401 aactgttgaa aaaatgatta ctctaggtaa acgtggtgat ttgcatgcac gtcgtcaagc
     2461 agctgctttc gtacgtaatg aaatcgcatc tgaaaactat gatgaagcaa ctgataagta
     2521 cacttctact acagcacttc aaaaattgtt ctcagaaatc gcacctcgtt atgctgaacg
     2581 taacggtgga tacactcgta tccttaaaac tgaaccacgt cgtggtgatg cagcgccaat
     2641 ggcgatcatc gaattagtat aaaatcatca attttgttga gtgttatgat gatggagtct
     2701 tgtgctctta gtctagctct ggtctaccgc taggatttcg gtcctagcgg gaacactcat
     2761 cataagttgg gatagtagac gcttgtttac gaaattgttt ttttcttaag aacaacttcg
     2821 taagcaggcg tttttgagta ttttcgttag aattatgcta tactatttga aaagaatcct
     2881 gtttaatgtt aaggtttctt attttaagaa gaattggagt ttacttatga aagccattat
     2941 aactgttgtt ggtaaagata aatctggaat tgttgcaggt gtttctggta aaattgcaga
     3001 attaggattg aatattgacg atatctctca aactgtcttg gatgaatatt ttacgatgat
     3061 ggctgttgta tctagtgatg aaaagcaaga ttttacctat cttcgtaatg aatttgaagc
     3121 ttttgggcaa actttgaatg taaaaatcaa tattcagagt gcagcgattt tcgaagctat
     3181 gtataatatc taggaggtca tcatggatat tagacaagtt actgaaacca tcgccatgat
     3241 tgaggagcaa aacttcgata ttagaaccat taccatgggg atttctcttt tggactgtat
     3301 cgatccagat atcaatcgtg ctgcggagaa aatctatcaa aaaattacga caaaggcggc
     3361 taatttagta gctgttggtg atgaaattgc ggctgagttg ggaattccta tcgttaataa
     3421 gcgtgtatcg gtgacaccta tttctctgat tggggcagcg acagatgcga cggactacgt
     3481 ggttctggca aaagcgcttg ataaggctgc gaaagagatt ggtgtggact ttattggtgg
     3541 tttttctgcc ttagtacaaa aaggttatca aaagggagat gagattctca tcaattccat
     3601 tcctcgcgct ttgactgaga cggataaggt ctgctcgtca gtcaatatcg gctcaaccaa
     3661 gtctggtatt aatatgacgg ctgtggcaga tatgggacga attatcaagg aaacggcaaa
     3721 tctttcagat atgggagcgg ctaagttggt tgtattcgct aatgctgttg aggacaatcc
     3781 atttatggcg ggtgcctttc atggtgttgg ggaagcagat gttatcatca atgtcggagt
     3841 ttctggtcct ggtgtggtga aacgtgcttt ggaaaaagtt cgtggacaga gctttgatgt
     3901 agtagccgaa acagttaaga aaactgcctt taaaatcact cgtatcggtc aattggttgg
     3961 tcaaatggcc agtgagagac tgggtgtgga gtttggtatt gtggacttga gtttggcacc
     4021 aacccctgcg attggagact ctgtggcacg tgtccttgag gaaatggggc tagaaacagt
     4081 tggcacgcat ggaacgacgg ttgccttggc cctcttgaac gaccaagtta aaaagggtgg
     4141 agtgatggcc tgcaaccaag tcggtggttt atctggcgcc tttatccctg tttctgagga
     4201 tgaaggaatg attgctgcag tgcaaaatgg ctctcttaat ttagaaaaac tagaagctat
     4261 gacggctatc tgttctgttg gattggatat gattgccatc ccagaagata cgcctgctga
     4321 aaccattgcg gctatgattg cggatgaagc agcaatcggt gttatcaaca tgaaaacaac
     4381 agctgttcgt atcattccca aaggaagaga aggcgatatg attgagtttg gtggtctatt
     4441 aggaactgca cctgttatga aggttaatgg ggcttcgtct gtcgacttca tctctcgcgg
     4501 tggacaaatc ccagcaccaa ttcatagttt taaaaattaa gaaaatagga gaaattttaa
     4561 gttctattta agattagatg tgtatactat aatcattaaa taaagacctc ctaatattat
     4621 ttgaaacaga taacactgaa ttagtttgaa tttgattttc atctaatatc tttatttaat
     4681 gaactcctaa actttttcat aataatctcc ttcaaaagtc gcctgtatgg gtggctttta
     4741 ttttatcatt catgatataa tagaagcaaa cggaggacgg aaaatggtaa aagtacgatt
     4801 gtatttggta cgtcatggca agaccatgtt taacacgatt ggtcgcgcgc aaggttggag
     4861 cgatactccc ttaactgctg aaggtgaacg agggattcaa gagttaggaa tcggtttgcg
     4921 agaatctgat ctacagtttg agcgcgctta ttcgagtgat tctggtcgta ccattcagac
     4981 catgggaatt atccttgaag aacttggctt gcaggggaaa atcccttatc gcatggacaa
     5041 gcgtatcaga gaatggtgtt tcggtagttt tgatggagcc tatgatggcg atcttttcat
     5101 gggcattatt cctcgtatct ttaatgtgga ccacgttcac caattgtctt atgctgaact
     5161 ggctgagggc ttggtagagg tcgatacagc tggttgggct gaaggctggg aaaaactcag
     5221 tggccgaatc aaggaaggct ttgaaatgat tgcaaaagaa atggaagatc aaggtggagg
     5281 taacgccctt gttgtcagcc atggaatgac tattggaacc attgtttatc tgattaatgg
     5341 catgcatccg catggtctag ataatggtag cgtgacgatt cttgaatatg aggacggtca
     5401 gtttagggtt gaagttgtcg gtgaccgtag ttaccgagag ctaggatgtg agaagatgga
     5461 agaaggctct atttaatcag tctagacttg cttgccatga gctagggatt tgataagaat
     5521 atcaagataa gaaaaaacag ccgagggcac tcctttcggc tgtttttgat gtggaaaact
     5581 aaagtgtaat gctattgctt ttagagattt tcataaacaa gagcaaggaa cctactgtta
     5641 gaacagtcag gatagttgac aaggctgcgg ctacaccgta atttcctctg agaacctctg
     5701 tataaatagc tacagtcatt gttcttgttt tgacattgta gaggaggata gaagtagaga
     5761 gttttgaaat cattgtgacc caagataaga tggctccaga aatgatacca gatagcatca
     5821 ttggagttgt aatcttagca aaggtattga gacgactact tcctaagctt tcagcagctt
     5881 cttcaatact tggtgctatt tgttgtaagc tagcaacaga tgagcgaata gtataaggta
     5941 atcttctgac agatagagac ataatcaaga tgaaagcagt ccctgtaatc ataagaaatc
     6001 cacttccaaa tagaccagta ttgaaggaag aaatgaaggc aatccctaga acggttcctg
     6061 gtacaatata aggtaccata ctgaggctgt caattaagtt tgtaaacaaa ttccgttttc
     6121 taacggctag gtaggagata aatgtcgcaa atagaacaac tagaactaag gcaatcaaag
     6181 ggatacgaat ggtattgaaa atagcagatc ccatacgatt gaaagctacc ttgtaactgt
     6241 ttggagaata acctttaaca gataccatac ctgatgtttt taggaaagag gtataaatta
     6301 agtagatttg aggtaaaaca gagataaaga taattccgta gactgttgca taaatggcag
     6361 ctatttttcc ttttgtagtt tttttaggct caattggatg gagcagattc atgctgaaac
     6421 tgtagcggtt tgcaatgtgt ttttggataa ggaaaattgc caaggcaatg ataatcgcca
     6481 taattgcaaa agcagaattt cctccaacct cgctaataaa ttgggtataa atcaggacag
     6541 ggaaagtccg atatccttcg tcaatcaaca taggcgttcc aaagtctgag aatgctctca
     6601 taaatacaag caaggagctg ctagtaaggt tggaactagg agaggtaaaa caaccgttac
     6661 gatacgctta aatccgaagg accccatgct ttcagctgct tcaagtagag aattgtcaat
     6721 actgttcatt gttccagcaa catatagaaa taccagtggg aatagttgca gtgtaaagac
     6781 aagtacaatt cctttgaatc cataaatatc gatagctgga agatgaaggg catttgtcaa
     6841 aaatttagtg atgacctcat ttcgtcccag caagagaatt caggagtagg ctcctacgaa
     6901 aggagctgac atggaagcaa tgataatcaa tatttgtaga aatttcttcc ccttgaagtc
     6961 atacatagag aagagataag ctaatagggt tcctacaact aaggaagtga tagtagcggt
     7021 aatggaaacc ttgaaactgt tgactagtgt ctcagagtag taggctttac taaagaaagt
     7081 gacaaaatta gctagtgaga attgtccttc atgtataagt gcttgcttga gcacggtaac
     7141 gataggataa acgagaaaga caagataggt aagaaagatg aagaaagagg aagctgtcca
     7201 aatatttagt tttttacatt ccatggttga ctccttttat caggttttgg gaaccatctg
     7261 cagaaaagat gtttaatttt tgcgtattga ttcgtagacg aatacgattg cctttttgta
     7321 gttcttcttc aaaagttgat tcttcactaa cttaaatttt tgaggcaaaa cctgtctcaa
     7381 tgaaatactc cgtatttagt ccaagataga cgctatcgct aatagttcct tcgatatctc
     7441 cagattcatc tttgataaac tcttcgggac gaatgcttac atgaatagct tgctcctcaa
     7501 cctgatcaag agctggcatt cgaagggcat agccatctga aaagacgata taagcgccgt
     7561 cgctccgttt ttcaagattg gcagggataa tatttgtgcg tccgataaag gttgccacaa
     7621 actcattagc tggtttatga tagagttatt ttggtcggcc gatttgttgg atcaccccat
     7681 ctttcataac agcaatttgg tctgaaatag ccatggcttc ttcttggtcg tgggttacat
     7741 aaacagttgt aattcccact tcgtgttgga tttctcggat ggcttgacgc atatccaagc
     7801 gaagtttggc ctccagatta ctaagtggct cgtccatgag gagaacactt ggattaaccg
     7861 ctaaggcgca tgccaaggtg acacgttgtt gttgtccacc actgagttta tcgggctttc
     7921 gatccgcata ttgagcaatt tgcatgagtt caagatactt gttggtctgt tgaatcaatt
     7981 cttcttttgg aaccttcttt tgcataagac caaaagcaac gttgtctcgg acagtcaaat
     8041 gtgggaaaat agcgtagttt tggaaaacca tcccgatatt gcgtttgctg ggttccatat
     8101 tattgatttt tgtatcatcg aagtaaaatt ctccaccttc gatactgttg aaacctgcaa
     8161 tcatacgaag aagggtcgtt ttcccacatc ctgaagctcc aagaagggta aagagacttc
     8221 cttttggaat tgtaatgttc aaattctcaa taacagggac atcgtggtag atttttttgg
     8281 cgttaataat ttcgatctca ctcatagtga acctctttta ctgtttagat tggatatctg
     8341 taaagacttc gttgtatttc ttaacgatat ctgatttatt cttgatgaca taatcataat
     8401 cttcagtgag tgttttgatt ttgtcaattg gtttcatgtt ttcgcttgtt ttagcatttt
     8461 tacgaacagg acggttagta gtggttgtac caagtgtatc ttgtacttct tgagagataa
     8521 taaaatcgat aaatttcttg gcattttcca tatttttaga ttttttaacg atagcagcac
     8581 tagcaggtag gaagacggtt ccttcttttg gatagactac cttaatgtta gctccgtcat
     8641 ttaagagttt aactgctgga tcttcataag agagactaac agtcatttct ccatcagcga
     8701 ctgctttata gacaccagat gaacttaaac cgattttata gtatattgaa actagaatag
     8761 tacacatcta cttctaaaac attgttagaa atcgatttga ctgtcctgat taatttgtcc
     8821 tgttcttatt tcattttact ataccatcaa taagtgtgaa aagatctttt acataagacc
     8881 aagccttatc atctttgtaa ccaccttgag cttgtagcat atttgttaat tgagcaaagg
     8941 cgctagaaga gtttgctggg tcagcagttg cgatttttcc ttttagttca ggtttgagaa
     9001 ggtcgctata tccttcgatg ttcatgcctt tagttaaatc agggtggacg attaaaacac
     9061 taccatctag tgtataagga gtagagaagc cagttgtgtt ttgatattct ttgataacat
     9121 tatcattttc ttttgaaata tagttttcaa agagttctcc gtgggtagca tattgtgtat
     9181 aagaaccacc aaagataata tcagctacag gaacttcttt ttctgactct agttttttga
     9241 aaagttctcc agtaccagct tgaatcagtt ctattttgat accatatttt tcttcaaagg
     9301 caggaatagt tgctccaatt aagccttctg agtttggtga ataaacgact agcgaaccac
     9361 cgtctccttt atcagatgaa ctgtcatcgg cagattcatt agaagaacaa gcagcataat
     9421 acatccattt ctttttcatg atggatacct ccgttgtgtt atttaagttt attttaaaac
     9481 aatgtaagcg tttttaaaac ctacaattct attctatagt gtattgaatc tataacagta
     9541 cacattgact gctaaaatat ttctataaat taatttgact ttcctgatag agatgttcac
     9601 atcttatttc aattcactat attagagtaa aattctctac aaaaaaaaag aatagcctat
     9661 tttactattt ttccgagtga tttcaattcc tttggggaaa tatggagata ctttttaaat
     9721 cctgacaaat ggttgtttct ttttctaaat cggtgatact gtatcggaga atgcgcgtga
     9781 ggtcacaaag gctgcgatag agcttctatg gagaatttct ttttggagag attttttaaa
     9841 ggaatgagac atccgctacc tccttggaag gtttttttgt gataagtata gcagtttaaa
     9901 aattctagag caaggtaaaa tagaaaaggt ttggctaaaa ttttttagct aaaccttttg
     9961 aaaagttaag tatgtattat agatgcttgt tatctgcaaa tagctagagc atttcaagga
    10021 aataaactag aaataacaat taatatggtg gttcagaaat accttttgat aatcaataag
    10081 atcttcagga tgaagtgcgt tgattccatc catttcatat ttccgattta ataaacgata
    10141 tttgttttca ccaaattgat gaaaagggag tagttgaact tggtcgatat ttaatgagtt
    10201 aaatagagta gcgaattttt ctgcatcctc taaactattg ttaaaattag gaataactgg
    10261 gattcttaaa acgatagttt tattttgtga aaaagcataa tgaatgtttt taataatcat
    10321 ttgattaaaa accccagtca cttttttatg ttttatagaa ttataatgtt ttaggtctgt
    10381 gtagataaaa tccacatatt gaattaaatc aataaatttt tcatgatcaa caaaggcagt
    10441 agtttcaatg gcagtgtgta tgtgatgttc tttagctgat tttaagatag ctttagcaaa
    10501 ttcaaactga gcaaatattt cacctcctga taaagttaaa cctccaccgg attcttcgta
    10561 aaattctttg tcttttaata cctctgtaat aatttcttct acagtctttt cttcaccgac
    10621 taaggtgaat ttctctcgtt gagcatcttt cattttttca ggtttcattc tttgagattc
    10681 aggattagaa caccatggac agcgcagagg acatcctttt aaaaaaacag ttgtacgaat
    10741 acccgggccg tcatgaattg aaaagtgttg aatattaaaa ataattcctt tagatatttc
    10801 cataagagtt cctcctcttc ataagtctat cctatcacaa aaacgaaaga aaaacaatta
    10861 cgaacgaaag gttaatttgt tgttttttgc tttttatttt ggtagaataa aacggaggtg
    10921 taaaatgaaa agattggaac aaattattaa attagtatca gaatatgaaa agatcgacgt
    10981 taatacatta tcggaaaaat taaatgtatc gaaagtaacg attagaaaag atttagataa
    11041 attagagtca aaaggtttat tacacagaga gcatggatat gctgtattaa atagtggaga
    11101 tgacttaaat gtacgtttgt caattaatta tgaaattaag agaaaaattg ttcaggaagc
    11161 agtaaaattg gtgtcagata atgaaacgat aatgatagaa tctggatcga cctgtgcttt
    11221 acttgctgag gaaatttgca agcaaaaaag aaatgttacg attgtaacaa attcattttt
    11281 tatagcaaat tttgtgagag cttatgattc atgtcgtatt attgttcttg gtggagagtt
    11341 tcagaaggat tcacaggtta ctgtgggacc tttattaaaa gaaatgatac agacttttca
    11401 tgtgcatcaa gcttttgttg ggacagatgg atacgataaa gagatgggct ttacaggaaa
    11461 agatttaatg cgcagtgagg tagttcaata tatttcagca gcgtcggata aagtcattgt
    11521 cctaactgac tcaagtaaat ttgataaaag gggtacagta agaagatttg ctttaagtca
    11581 agtctatgaa gtaataacag acgaaaaact ttctaaacaa aatatagcta cattagaaaa
    11641 tgctgggata atggttaagg tagtttcgta agaggttaag tgtatgaatc aagataggaa
    11701 taaactgctc tctaaaattg cttatctgta ttatattgaa aacttaaatc agtcacaaat
    11761 agcagcaaaa ttaggaattt atagaacctc tattagtaga atgttaacag aagcaaggaa
    11821 tgcaggaatt gttaaaattg aaatagagaa ttttgatacc aatatgttta agttggaaaa
    11881 ttatgtaaaa gaaaaatatg gtctggaaag tttagaaatt attccaaatg aatttgatga
    11941 taatccaaca attttatctg aaagaatttc tcaagttgca gcaggtgtcc ttaggaatct
    12001 aattgatgat aatatgaaaa ttggcttttc ttgggggaaa agtttaagta atttagtaga
    12061 tttaattcac agtaaaagtg tccgaaatgt tcacttctat cctctagcag gtggtcctag
    12121 tcacatacac gctaaatacc atgtgaatac actgatttat gaaatgtcta gaaaatttca
    12181 tggagagtgt acatttatga atgcaacgat tgtgcaagaa aataaattgt tagcagatgg
    12241 tattttgcaa tcaagatatt ttgaaaattt gaaaaatagt tggaaagatt tagatatagc
    12301 tgtagtcgga attggtgatt ttagcaataa aggaaagcat caatggttag acatgcttac
    12361 agaggatgac tttaaagaat tgaccaaagt taaaactgta ggagaaattt gttgtcgatt
    12421 ttttgattca aaaggtaaag aagtctatga aaacttacag gaaagaacga tagcaatctc
    12481 tttggaagat ttaaaaaata ttcctcaaag tttagctgtt gcttacggtg atacgaaagt
    12541 atcttcgatt ctttctgtct tgcgtgctaa tttagtaaat catttgatta cagacaaaaa
    12601 tacaatttta aaagttttgg aagaagatgg ggatttgact tttagagaga ttctaggtga
    12661 gtgaaaatga tagactgatt cagtttatcg tttttctttt tagttgattg cacatttgtg
    12721 cttatataaa caaaaatagt ttatctgttg tttttggatt gacaacttta ttatgtagtt
    12781 gtattctata gttacaaaag aaaattttaa aatttcaaat gaaaaaagct ttttacatag
    12841 tgaaatgagg aggaatttat ggaaattatt gttccagatc aaattatcat gggtttaatt
    12901 ttatatgctg gtgatgcgaa acaacatatt tataaagcgt tagattacat aaaaaatggt
    12961 acatgtgaac ggtgtgaaga agaaatccag ttagctgatg ccgccttatt agaagcccat
    13021 aatctacaaa caaaattctt ggcacaagaa gcgtctggta caaagacaga aattacagct
    13081 ctctttgttc attcacaaga tcatctcatg actagtatga cggagattaa tttaatcaaa
    13141 gaaattatta gtttgagaaa agaacttcat aaaaaataat actagagtat tatcattgtt
    13201 attaacatag aggaggaaaa cataatggtg aagattggtt tgttttgtgc agcaggtttt
    13261 tctactggta tgcttgtaaa taatatgaaa attgcagcgc aatctagtgg agttgaggca
    13321 gaaatagagg cgttttctca gtctaaatta gcggattatg cgccaaatat agatgttgca
    13381 ctattgggtc cacaagttgc ttatacatta gataaatcaa aagaaatttg tgataagtgt
    13441 gatgttccga tagctgttat tccgatgatg gactatggta tgttagatgg gaaaaaagta
    13501 ttagatttgg ccctatcttt gattagtggg taagaaaagg agatttatta tgtcaaagat
    13561 ggatgttcag aaaatcattg caccgatgat gaagtttgtg aatatgcgtg gcattatagc
    13621 tctaaaagat gggatgttag caattttgcc attgacagta gttggtagtt tgttcttgat
    13681 tatgggacaa ttgccgttcg aaggattaaa taagagcatt gctagtgttt ttggagctaa
    13741 ttggacagag ccgtttatgc aagtatattc aggaactttt gctattatgg gtctaatttc
    13801 ttgtttttca attgcctatt cttatgctaa gaatagcgga gtagaggctt taccagctgg
    13861 agttctatct gtatctgcat tctttatttt gctaagatca tcttatatcc ctaaacaagg
    13921 tgaggcgatt ggggacgcta ttagtaaagt ttggtttgga ggccaaggaa ttatcggtgc
    13981 tatcattata ggtttggtag taggaagtat ttataccttc tttataaaga gaaaaattgt
    14041 tattaagatg ccagaacaag ttccacaagc tattgccaaa cagtttgaag caatgattcc
    14101 agcatttgta attttcttat cttctatgat tgtatatatt ttagcgaagt cattgactaa
    14161 tggcggaaca ttcatagaaa tgatttattc tgctattcaa gttccgttgc aaggtttaac
    14221 tggatctttg tatggtgcta ttggaattgc attctttata tcatttttgt ggtggtttgg
    14281 tgttcatggg caatcggtag taaatggagt agtgacagct ctgcttttat ctaatcttga
    14341 cgctaataaa gctatgttag cctctgctaa tctatcatta gaaaatggtg cacatattgt
    14401 tactcaacaa tttttagatt catttttaat tctatcaggt tcagggatta cgtttggtct
    14461 tgtagttgcc atgctttttg cagcaaaatc aaaacaatac caaaccttag gaaaagttgc
    14521 agcttttcca gcaatattta acgtaaatga gccagttgta tttggatttc cgattgtcat
    14581 gaatccagtt atgtttgtac ctttcattct tgttcctgta cttgcagctg tgatagtata
    14641 tggagctatt gcaacaggtt tcatgcagcc attctcaggg gtaacattgc cttggagtac
    14701 accagctatt ttatcaggat ttttggtggg tggatggcaa ggagttatta ctcagctggt
    14761 gatattagcg atgtctacat tggtttattt tccattcttt aaagtacagg atcgtttagc
    14821 ttaccaaaat gaaatcaaac aatcttagag gtatttgtgt gttactgtta aactcacaca
    14881 tttgtgctaa aaattagaga gttaaaattt ttctagttaa aagcttgaaa atttctataa
    14941 aaatcggtat tatattttcg aaagaaataa aaatattttc gaaagaaagg tggttacgat
    15001 ggtaaataca gaagtagcaa gaacaacaat caagacagaa tattttggca gccttactga
    15061 aaggatgaac aaatatcgag aagatgtttt aaataaaaaa ccttatattg atgctgagag
    15121 agcagttcta gcaacacgcg cctatgaacg atacaaggaa caacctaatg tcctaaaacg
    15181 tgcatatatg ctgaaagaaa ttttggaaaa tatgactatc tatattgaag aagaatctat
    15241 gattgcggga aatcaagctt cttccaataa agatgctcct atttttccgg aatatacgct
    15301 agaatttgtt ctcaatgagt tggatctttt tgaaaagcgt gatggagatg ttttctatat
    15361 tacagaagaa acaaaagaac aacttagaag tattgctccg ttttgggaaa ataataattt
    15421 acgtgctaga gctggtgcct tattacctga agaagtgtct gtttatatgg aaacaggatt
    15481 cttcggtatg gaaggtaaga tgaattctgg agatgctcac ctagcagtta actatcagaa
    15541 acttttgcaa tttggtttaa gaggttttga agagcgggct cgtaaagcaa aagtagctct
    15601 agatttaaca gatccagcaa gtattgataa atatcatttt tacgactcta tatttatcgt
    15661 aatcgatgct attaaagtat atgcaaagcg ctttgttgct cttgctaaaa gtttagccga
    15721 aaatgcaaat cctaaacgta agaaagaatt acttgagatt gcagatattt gctctagagt
    15781 cccatatgaa ccggcaacta cttttgcaga agctattcaa tcagtttggt ttattcaatg
    15841 tattttacaa attgaatcta atggccactc tctttcatat ggccgttttg atcaatatat
    15901 gtatccatat atgaaggctg atttagaaag tggtaaagaa acagaagata gcattgttga
    15961 acgtctgaca aatctttgga ttaagacaat tacaatcaat aaggttcgca gtcaatcaca
    16021 tacattttct tcagcaggaa gtcctttata tcaaaatgtt acaattggtg gacagactcg
    16081 agataagaag gatgctgtta acccattatc ttatttggta ttaaaatcag ttgcacaaac
    16141 ccatctaccg caacctaatc taactgtacg ttaccatgca ggtttagatg ctcgtttcat
    16201 gaatgagtgt attgaagtga tgaaacttgg ttttggtatg cctgcattta ataatgatga
    16261 gattattatt ccttctttta ttgcaaaagg agtattggaa gatgatgctt atgattacag
    16321 tgccattgga tgtgttgaaa cggcagttcc agggaaatgg ggctatcgtt gcacaggtat
    16381 gagttatatg aacttcccta aggttctact tatcacgatg aatgatggaa ttgatccggc
    16441 ttcgggtaaa cggtttgcac caagctttgg tcattttaag gatatgaaga acttttctga
    16501 attagaaaat gcttgggata aaacactaag atatttgaca cgaatgagtg ttattgttga
    16561 aaattctatt gatttatcat tggaacgaga agttcctgat attctatgtt cagcattgac
    16621 tgatgattgt attggtcgtg gaaaacacct taaagaaggt ggagcagtat atgattatat
    16681 atcaggattg caagttggaa ttgcaaattt gtcggattca ttagctgcaa ttaaaaaatt
    16741 ggtgtttgag gaagaacgta taagcccaag tcagctttgg catgcactgg aaacagatta
    16801 tgccggagaa gaaggtaagg tcattcaaga aatgttgatt catgatgcac ctaagtatgg
    16861 taatgatgat gattatgctg acaaattggt tactgctgct tatgacattt atgttgatga
    16921 aattgctaaa tatcctaata cacgttatgg aagagggcct attggaggaa ttcgttattc
    16981 aggaacatct tctatctcag ccaacgtagg gcagggacgt ggaacattag caactccaga
    17041 tggacgcaac gcgggtacac cgttagcaga gggttgttca ccatcacata atatggatca
    17101 acacggccct acatctgttt taaaatctgt ttcaaaatta ccaacagatg aaatcgtagg
    17161 tggggttctc ttaaatcaga aagtaaatcc tcaaacgtta gccaaagaag aagataaatt
    17221 aaaactaatt gctttgttac gaacattctt taatcgttta catgggtacc atattcaata
    17281 caatgttgtt tccagagaga cgttgattga cgctcagaaa catcctgaaa aacacagaga
    17341 cttaattgtt cgtgttgcag gatactctgc attcttcaat gttctttcta aggcaaccca
    17401 agatgacatt ataggacgta ctgagcatac tttgtaaaat aaagaggttc tttttatgga
    17461 atttatgctt gacacattaa atttagatga gattaaaaag tggtctgaaa ttttgccgct
    17521 agctggggta acttcaaatc ccactattgc aaaaagagag ggttctatta atttttttga
    17581 acgaatcaaa gatgtaagag aattgattgg ctctacaccc tctattcatg ttcaggtgat
    17641 ttctcaagat tttgaaggca tcttaaagga tgctcatgaa attcgaagac aagcaggaga
    17701 tgatatattt atcaaagtac ctgttactcc agctggatta cgtgcaataa aggtgctaaa
    17761 aaaagagggc taccatatca ctgcaacagc tatttataca gttattcagg gattattagc
    17821 tatcgaagta ggagcggatt acctagctcc atattataat agaatggaaa atctgaacat
    17881 tgattcaaat tctgtcattc gtcaattagc tcttgctatt gatagacaga actctcctag
    17941 taagatttta gctgcatcct ttaaaaatgt agcacaagta aataatgctt tagctgcagg
    18001 tgcgcatgct gttacagcag gagcagatgt ttttgaatca gctttcgcca tgccatctat
    18061 ccaaaaggcg gttgatgatt tttctgacga ttggtttgtt actcaaaata gtcgttccat
    18121 ttagatagag aggaaataca tatgagaatt tttgctagtc cttctagata tattcagggg
    18181 gaaaatgcct tgtttgaaaa tgccaaatca attttggatt tgggaaatta ccctattcta
    18241 ttatgcgatc agttggttta tgatattgtt ggaaaacgat ttgaagatta tctacatagg
    18301 tatggtttcc atattgttct ggcgctattt aatggtgaag cttctgacaa tgaaatcaat
    18361 cgagttgttg ccttggctga gaaagaaaat tgtgatagta ttatcggtct tggtggggga
    18421 aagacgattg atagcgcaaa agctattgca gatttgattg aaaagcctgt tattattgct
    18481 ccaacaattg catcgaccga cgcacctgta tctgctttat ctgttattta tacagatgaa
    18541 ggtgcatttg atcattatct attttattct aaaaatccag atttagtttt ggttgataca
    18601 aaagttattt cacaagcccc taagcgttta ttagcgtctg gtattgcaga tggtttagca
    18661 acttgggttg aggcgcgtgc ggttatgcag gcaaatggaa aaactatgtt gggacaacag
    18721 caaacattgg ctggagttgc aattgcgaag aaatgtgaag aaacgctgtt tgcagatggt
    18781 ttacaggcta tggcagcttg tgaagctaaa gtggtgacac cagcattaga aaatattgtt
    18841 gaagctaata ctttattgag tggcctaggt tttgaaagtg gaggattagc tgcggcgcat
    18901 gcaattcata atggttttac tgcattgaca ggtgacattc atcatttaac acatggtgaa
    18961 aaagtagctt atggaacttt agtacaacta ttattggaaa atagacctaa agaagaactt
    19021 gataagtata ttgagtttta caaaaaaatt ggtatgccaa caactctaaa agaaatgcat
    19081 ttggatcaag ttggatatga tgatttaata aaagttggta aacaagcaac tatggagggt
    19141 gagacaattc atcagatgcc gtttaagatt tcgccttcag atgttgctca agctattatc
    19201 gctgtagatg cctatgtaaa ttcaaaataa acaataagga ctactgtttt ccaaatggta
    19261 gtcttttatt gatcctcgta ttgaattcta tagcagattg aaataagatg agaacaaatc
    19321 gattgggaaa gtaaaattaa tttctataag tattttagca attgtttcgt actatttcag
    19381 attcagtcca ctatacgttc ttcataaatc aaaaagcgac ataggttgtc ggctatttat
    19441 tgtgaataca ttaattagca ttccagtttt atcttcggtc taaaataagt attttgtgct
    19501 atacgagata agtttcttga cttactcctt gatttactgc ataacaatgg gataaaaagt
    19561 gggagataga gcaattcata gtcatcaaaa ttaatgagat acagtataca gtttttcctt
    19621 taaacacatt tcaaattccc tcaaaaatgg tataatagta acatcacaaa attggagaga
    19681 gaccatgagt ttttacaatc ataaagaaat tgagcctaag tggcagggct actgggcaga
    19741 acatcataca tttaagacag gaacagatgc atcaaaacct aagttttatg cgcttgatat
    19801 gttcccttat ccgtctggag ctggtctgca cgtaggacac ccagaaggtt atactgcaac
    19861 cgatatcctc agtcgttaca aacgtgcgca aggctacaat gtccttcacc caatgggttg
    19921 ggatgctttt ggtttgcctg cagagcaata cgctatggat actggtaatg acccagcaga
    19981 atttacagcg gaaaacattg ccaacttcaa acgtcaaatc aatgcgcttg gattttctta
    20041 tgactgggat cgtgaagtca acacaacaga tccaaactac tacaagtgga ctcaatggat
    20101 tttcaccaag ctttacgaaa aaggcttggc ctatgaagct gaagtgccag taaactgggt
    20161 tgaggaattg ggaactgcca ttgccaatga agaagtgctt cctgacggaa cttctgaacg
    20221 tggaggctat ccagttgtcc gcaaaccaat gcgccaatgg atgctcaaaa tcacggctta
    20281 cgcagagcgc ttgctcaatg acttagatga actagattgg tcagagtcta tcaaggatat
    20341 gcaacgcaac tggattggta aatcaactgg tgccaatgta actttcaaag taaaaggaac
    20401 agacaaggaa tttacagtct ttactactcg tccggacaca cttttcggtg cgactttcac
    20461 tgttttggct cctgaacatg aattagtaga tgccatcaca agcacagagc aagcagaagc
    20521 agtagcagac tacaaacacc aagccagcct taagtcagac ttggctcgta ccgaccttgc
    20581 caaagaaaaa actggtgtat ggactggtgc ttatgccatc aatcctgtca atggtaagga
    20641 aattccaatc tggattgcgg attacgttct tgctagctat ggtacaggtg cggtaatggc
    20701 tgtgcctgcc cacgatcaac gtgactggga atttgccaaa caatttgacc ttccaatcgt
    20761 cgaagtactt gaaggtggaa atgttgaaga agctgcctac acagaagatg gccttcacgt
    20821 taattcagac ttcctagatg gactcaacaa agaagacgct attgccaaga ttgtggcttg
    20881 gttggaagaa aaaggctgtg gacaagagaa ggtaacctac cgtctccgcg actggctctt
    20941 tagccgtcaa cgttactggg gtgagccaat cccaatcatt cattgggaag atggaacttc
    21001 aacagctgtc cctgaaagtg aattgccact tgttttgcct gtaaccaagg atatccgtcc
    21061 ctcaggtact ggtgaaagtc cactagctaa cttgacagac tggcttgaag tgactcgtga
    21121 agatggtgtc aaaggtcgtc gtgaaacaaa tactatgcca caatgggcag gttcaagctg
    21181 gtactacctc cgctatattg acccacacaa tactgagaaa ttggctgacg aggatctgct
    21241 caaacaatgg ttgccagtag atatctacgt gggtggtgcg gaacatgctg tacttcactt
    21301 gctttacgct cgtttctggc ataaattcct ctatgacctc ggtgttgttc caactaagga
    21361 accattccaa aaactcttta accaaggaat gattttggga acaagctatc gtgaccaccg
    21421 tggggctctt gtggcgactg acaaggttga aaaacgtgat ggttctttct tccatgtgga
    21481 aacaggggaa gagttggagc aagcgccagc caagatgtct aaatcgctca agaacgttgt
    21541 caacccagac gatgtggtgg aacaatacgg tgctgatacc cttcgtgtct atgaaatgtt
    21601 catgggacca ctcgatgctt cgattgcttg gtcagaagaa ggtctggaag gaagtcgtaa
    21661 gttccttgac cgtgtttacc gtttgattag aagtaaggaa attgttgcgg aaaacaatgg
    21721 cgctcttgac aaggtttaca acgaaactgt taaagctgtc acagagcaaa ttgattccct
    21781 caaattcaac acagccattg cccaacttat ggtctttgtc aatgcggcta acaaggaaga
    21841 caagctctat gttgactatg ccaaaggatt tatccaattg attgccccat ttgcacctca
    21901 cttggcagaa gaactctggc aaactgttgc tgcaacaggt gagtcaatct cttacgtgac
    21961 ttggccaaca tgggacgaaa gtaaactggt tgaagacgaa atcgaaatcg ttgtccaaat
    22021 caaaggtaaa gtccgtgcca aactcatggt cgctaaagac ctatcacgtg aagaattgca
    22081 agaaattgct ctagcggatg aaaaagtcaa agcagaaatt gacggtaagg aaatcgtgaa
    22141 agtgattagt gtaccaaata aattggttaa tattgttgta aaataaccaa tttatttgct
    22201 gatttccaac ctcaaacagt ttcccaaact gtttgagcca actaaactcg ttaatatcgt
    22261 tgtgaaataa ggtaggaatc cttcagagta gaatctggag gattttttga atcttcttat
    22321 gaaagtatgg tatactatgg gcaactataa agtttgaaaa gtgaaaaaag gagaaagcta
    22381 tgccagtaaa tgaatatggt caaatgattg gggagtcaat ggaaggttat acaccaggtg
    22441 aactgccttc tattgatttc ttagaagggc gttatgctag gatagaggct ctttcagtgg
    22501 aaaagcatgc ggaggatttg ctagctgttt atgggcctga tacgcctcag gagatgtgga
    22561 cctacctttt tcaggagcca gtagcagata tgggggagct ggttagcctt ttacatcaga
    22621 tgttggctcg taaggaccgt ttttactatg caatcataga caaggcgact ggtaaggctt
    22681 tgggatcttt ttctctcatg cgcattgacc agaataaccg agtaatagaa gtcggagcag
    22741 tcactttttc tccagagcta aggggtacac ggataggaac tgaagctcag tatctcctag
    22801 ctcgctatgt ttttgaggag ctaaactatc gtcgctacga gtggaaatgc gatgccttaa
    22861 atctgccatc cagacgagct gcggagcgtt tgagctttat ttatgaagga accttccgtc
    22921 aggcagtggt ttataaggga cgtacgagag atacggattg gttgtctatg attgataagg
    22981 actggcctca agtcaaagat cgtttggaaa catggttgcg tcctgaaaat tttgataaaa
    23041 atggacagca gtacaagagc ttgagagaac tttaagaggt gttgagatga ttactattaa
    23101 aaagcaagaa attgtcaagc tagaggatgt tttacatctc tatcaggctg tcggttggac
    23161 aaattatacc catcaaccag agatgctgga gcaggcctta tctcattcat tagtaattta
    23221 tctggcactt gatggtgatg ctgtggtggg cttgattcgt ttggttggag atggattctc
    23281 atcagtattg gttcaggatt taatcgtttt accaatctat cagcgtcaag gaattggtag
    23341 tgccttgatg aaagaggctt tagaggatta caaagatgcc tatcaagtcc agctggtgac
    23401 agaagagaca gaaagaacct tgggcttcta tcgttctatg ggctttgaaa tcttatccac
    23461 ctataattgt atagggatga cttggatgaa tcgtaaaaaa taacaaaact tgttttttct
    23521 taagcaaaat ttaaggatgg tctagtatta tatagtcatt aaataaagac ctcctaactt
    23581 tatttaataa aatcctaaac ttttcttttt cataataatc tcccttaact ccacccaatc
    23641 aggtggagtt ttttagctct atttcaggct tttggggact attctaaaaa taatttttcg
    23701 atatttttcg gtatttttcg gattttggtc ggggaattgg cggggacttt tttagcgaat
    23761 ataactaaga aataggtctg tggtcgcttc agctagttca aactcaattt gattgtaagt
    23821 gactgttaat tgaagaactg gaactactgt aataatgatt ttgcttgtct agtagtggcg
    23881 tattaaatga gaagtgacat gtaagattgt ctcttcgttt acgaaatcaa aatttctatg
    23941 aaattgatag aatccctaac gttctcttaa tcttaaccgt cttgtcgtac agcggttgaa
    24001 gaaaatgtaa acctttgaca aaattcgtga actatgggat aataaaaagg aattgagtac
    24061 tagttctata tcataggcta gaaaagaccc caagctcacg accaaataag cttgaggtct
    24121 tttttgacac tatttgtcct tgtttagcca tttatcgact atacgaagaa cgacaccgac
    24181 cacaattggt ccgatgatag ttttgagtac taattccatc atgggctatc tcacctcctt
    24241 tcgtaggcgg tgtagcagtg tcgtagaata ttataccaca taagtgctaa acttaggagt
    24301 cacccaatca ggtggctttt ttgtttgtgg cttggttttt tgatataata gagccatgag
    24361 tagaatttta gataatgaga taatggggga tgaggagtta gtagaacgca cgctccgtcc
    24421 tcagtattta cgtgaatata tcggacagga taaggtcaag gaccagctac aaatctttat
    24481 tgaagctgcc aaaatgcggg atgaagcgct ggatcatgtg ctcttatttg ggcctccagg
    24541 tctcgggaaa acgaccatgg cctttgttat tgccaacgaa ctgggagtca atcttaagca
    24601 gacgtcgggt ccagtcattg aaaaagccgg agatctggta gctattttga atgagttaga
    24661 gcctggggat gtacttttta ttgatgagat ccatcgtttg ccaatgtcag tggaagaggt
    24721 gctttatagt gctatggagg acttctacat agatattatg attggggctg gtgagggtag
    24781 tcgtagtgtt catttggagt taccaccttt taccttgatt ggtgcgacga ctcgggctgg
    24841 tatgctctcc aatccgctac gggcacgttt tgggattaca ggccatatgg agtattatgc
    24901 ccatgctgac ttgacagaaa ttgtcgagcg gacggcagat atttttgaga tggaaatcac
    24961 tcatgaggca gcatctgagt tggccctacg tagtcgtggg acccctcgta ttgccaatcg
    25021 tctcctcaag cgcgtgcgcg attttgccca gataatgggg aatggggtaa ttgatgatat
    25081 tattaccgat aaggctttga ctatgctgga tgttgaccat gaaggtttgg actatgtgga
    25141 tcaaaaaatc cttcgtacca tgattgagat gtacagtgga ggacctgttg gtctaggaac
    25201 tctttctgtg aatatcgccg aagagcgtga gacagttgaa gatatgtatg agccttactt
    25261 gattcaaaaa ggttttatca tgcggacacg gtctggacgg gtggcgactg ctaaggcata
    25321 tgagcactta ggttatgaat acagtgaaaa ataagcaaga aatcttagag gcttttagag
    25381 aaaatccaga tatgatggcc attctgacga tcatccgaga ccttggtctg aaagactcgt
    25441 ggttggcagc aggttctgtc agaaatttca tttggaatct tttgtcagac aaatcccctt
    25501 ttgatcatga aacagatata gatgtgattt tctttgatcc agatttttct tatgaggaaa
    25561 ccttattact ggagaaaaag ctgagagagg attttcctca gtaccagtgg gaattgaaaa
    25621 atcaggtcta tatgcatcag cacagtcctc acactgcttc ctataccagt tctcgtgatg
    25681 ctatgagtaa gtatccagaa cggtgtacgg cagttggact gcgcttgaat gaagaatcag
    25741 attttgaact ctatgcacct tatggtttgg aggatatttt gaattttcaa gttcgtccaa
    25801 ctcctcattt cttagaaaat gaagaccgaa tggaactcta tcaaacacgt ttatccaaga
    25861 aaaattggca ggagaaatgg aaaaatttga tttttaaaaa tacttaagga aactttaagc
    25921 tagggagtgt acactaagtt cataagttaa gaagacctta acttaaactc ctaaaacttt
    25981 ttcataataa tctccctata aaaataaagt cgcccaatca ggcggcttat ttttttgaaa
    26041 aatgggcatg gtgcctgaga ataaatagct tagtgataga agaaaatggg gaaatatggt
    26101 ataatgaaac gatagatttt tgaataggaa taagatcatg tttggatttt ttaagaaaga
    26161 taaggctgtg gaagtagagg ttccgacaca ggttcctgct catatcggca tcatcatgga
    26221 tggcaatggc cgttgggcta aaaaacgtat gcaaccgcga gtttttggac ataaggcggg
    26281 catggaagca ttgcaaaccg tgaccaaggc agccaacaaa ctgggcgtca aggttattac
    26341 ggtctatgct ttttctacgg aaaactggac ccgtccagat caggaagtca agtttatcat
    26401 gaacttgcca gtagagtttt atgataatta tgtcccggaa ctacatgcga ataatgttaa
    26461 gattcaaatg attggggaga cagaccgcct gcctaagcaa acctttgaag ctttaaccaa
    26521 ggctgaggaa ttgactaaga acaacacagg attgattctt aattttgctc ttaactatgg
    26581 tggacgtgct gagattacac aggcgcttaa gttgatttcc caggatgttt tagatgccaa
    26641 aatcaaccca ggtgacatca cagaggaatt gattggtaac tatctcttta ctcagcattt
    26701 gcctaaggac ttacgagacc cagacttgat tatccgtact agtggagaat tacgtttgag
    26761 caattttctt ccatggcagg gagcctatag tgagctttat tttacggaca ccttatggcc
    26821 tgattttgac gaagcggcct tgcaggaagc tattcttgcc tataatcgtc gtcatcgccg
    26881 atttggagga gtttaggagg aaatatgacc caggatttac agaaaagaac cttgtttgca
    26941 gggattgccc tggctatttt cctaccaatt ttaatgattg ggggcctctt gcttcagata
    27001 gcaatcggaa tcatagccat gctagccatg catgaacttt tgaagatgag aggtctagag
    27061 accatgacga tggagggcct cttgaccctc tttgcaacct ttgcattgac cattcccttg
    27121 gagaattacc tgactttttt gccagttgat gggaatgtgg ttgcctatag tgttttgatt
    27181 tcaatcatgt taggaacgac cgtttttagc aagtcttata cgattgagga tgcggttttc
    27241 cctcttgcta tgagcttcta cgtgggcttt ggatttaatg ctttactaga tgctcgtgtt
    27301 gcaggtttgg acaaggctct cttagccttg tgtatcgtct gggcgacaga cagtggtgcc
    27361 tatcttgttg ggatgaacta tgggaaacga aagttagcac caagggtatc gcctaataaa
    27421 acccttgagg gtgccttggg tggtatttta ggagcaattt tagtaaccat tatctttatg
    27481 atagttgaca gtacagttgc tcttccatat ggaatttaca agatgtcagt ctttgctatt
    27541 ttctttagca ttgctggaca atttggtgat ttactagaaa gttcgatcaa acgtcatttt
    27601 ggtgttaagg attctgggaa atttatccct ggacatggtg gtgttttgga tcgtttcgat
    27661 agtatgttgc ttgtatttcc aatcatgcac ttatttggac tcttttaatc aaaagacgga
    27721 ggaaacgcta tgctcggaat tttaaccttt attctggttt tcgggattat tgtagtggtg
    27781 cacgagttcg ggcacttcta ctttgccaag aaatcaggga ttttagtacg tgaatttgcc
    27841 atcggtatgg gacctaaaat ttttgctcac attggcaagg atggaacggc ctataccatt
    27901 cgaatcttgc ctctgggtgg ctatgtccgc atggccggtt ggggtgatga tacaactgaa
    27961 atcaagacag gaacgcctgt tagtttgaca cttgctgatg atggtaaggt taaacgcatc
    28021 aatctctcag gtaaaaaatt ggatcaaaca gccctcccta tgcaggtgac ccagtttgat
    28081 tttgaagaca agctctttat caaaggattg gttctggaag aagaaaaaac atttgcagtg
    28141 gatcacgatg caacggttgt ggaagcagat ggtactgagg ttcggattgc acctttagat
    28201 gttcaatatc aaaatgcgac tatctggggc aaactgatta ccaattttgc aggtcctatg
    28261 aacaatttta tcttaggtgt cgttgttttt tgggttttaa tctttatgca gggtggtgtc
    28321 agagatgttg ataccaatca gttccatatc atgccccaag gtgccttggc caaggtagga
    28381 gtaccagaaa cggcacaaat taccaagatt ggctcacatg aggttagcaa ctgggaaagc
    28441 ttgatccaag ctgtggaaac agaaaccaaa gataagacgg caccgacttt ggatgtgact
    28501 atttctgaaa aggggagtga caaacaagtc actgttacac ccgaagatag tcaaggtcgt
    28561 taccttctag gtgttcaacc gggggttaag tcagattttc tatccatgtt tgtaggtggt
    28621 tttacaactg ctgctgactc agctctccga attctctcag ctctgaaaaa tctgattttc
    28681 caaccggatt tgaacaagtt gggtggacct gttgctatct ttaaggcaag tagtgatgct
    28741 gctaaaaatg gaattgaaaa tatcttgtac ttcttggcaa tgatttccat caatattggg
    28801 atttttaatc ttattccgat tccagccttg gatggtggta agattgtgct caatatccta
    28861 gaagccatcc gccgcaaacc attgaaacaa gaaattgaaa cctatgtcac cttggccgga
    28921 gtggtcatca tggttgtctt gatgattgct gtgacttgga atgacattat gcgactcttt
    28981 tttagataat cgaggaatat tatgaaacaa agtaaaatgc ctatcccaac gcttcgcgaa
    29041 atgccaagcg atgctcaagt tatcagccat gctcttatgt tgcgtgctgg ttatgttcgc
    29101 caagtttcag caggtgttta ttcttatcta ccacttgcca atcgtgtgat tgaaaaagct
    29161 aaaaacatca tgcgccaaga attcgaaaag attggtgctg ttgagatgtt ggctccagcc
    29221 cttcttagtg cagaattgtg gcgtgaatca ggtcgttacg aaacctatgg tgaagacctt
    29281 tacaaactaa aaaaccgtga aaaatcagac tttatcttag gtccaactca cgaagaaacc
    29341 tttacagcta ttgtccgtga ttctgttaaa tcttacaagc aattgccact caacctttat
    29401 caaattcagc ccaagtatcg tgatgaaaaa cgcccacgta atggacttct tcgtacacgt
    29461 gagtttatca tgaaggatgc ttatagtttc cacgctaact atgatagttt ggatagtgtt
    29521 tatgatgagt acaaagcagc ctatgagcgt attttcactc gtagtggttt agacttcaag
    29581 gctattattg gtgacggtgg agccatgggt ggtaaggata gccaagaatt tatggccatt
    29641 acatctgctc gtacagacct tgaccgctgg gttgtcttgg acaagtcagt tgcctcattt
    29701 gacgaaattc ctgcagaagt gcaagaagaa atcaaggcag aattgctcaa atggatagtc
    29761 tctggtgaag ataccattgc ttactcaagt gagtctagct atgcagctaa cttagaaatg
    29821 gcaacaaacg agtacaaacc aagcaaccgt gttgtcgctg aagaagaagt tactcgtgtt
    29881 gcaacgccag atgttaaatc aattgatgaa gttgcagctt tcctcaatgt tccagaagaa
    29941 caaacgatta aaaccctctt ctacattgca gatggtgagc ttgttgcagc ccttctagtt
    30001 ggaaatgacc aactcaacga agtcaagttg aaaaaccact taggagcaga tttctttgac
    30061 gttgctagcg aagaagaagt ggcgaatgtt gttcaagcag gatttggttc acttggacca
    30121 gttggtttgc cagagaatat taaaattatt gcagatcgta aggtgcaaga tgttcgcaat
    30181 gcagttgtcg gtgctaacga agatggctac cacttgactg gtgtgaaccc aggccgtgat
    30241 tttactgcag aatatgtgga tatccgtgaa gttcgtgagg gtgaaatttc cccagatgga
    30301 caaggtgtcc ttaactttgc gcgtggtatt gagatcggtc atattttcaa actcggaact
    30361 cgctactcag caagcatggg agcagatgtc ttggatgaaa atggtcgtgc tgtgccaatc
    30421 atcatgggat gttacggtat cggtgtcagc cgtcttcttt cagcagtgat ggagcaacac
    30481 gctcgcctct ttgttaacaa aacgccaaaa ggtgaatacc gttacgcttg gggaatcaat
    30541 ttccctaaag aattggcacc atttgatgtg catttgatta ctgtcaatgt caaggatgaa
    30601 gaagcgcaag ccttgacaga aaaacttgaa gcaagcttga tgggagctgg ttatgaagtc
    30661 ttgacagatg accgtaacga acgtgtcggt gttaaattta gcgatagtga cttgattggt
    30721 cttccaatcc gtatcactgt tggtaaaaaa gcggccgatg gcattgtaga agttaagatc
    30781 aaggcaactg gtgacaccat tgaggttcat gcagataacg tgcttgaaac gcttgaaatc
    30841 ctaagcaaga aataaaaact ataatcagaa gaaaaacaag gaaaaaatgt aactagtttt
    30901 taccttgttt tttctgtata atgggagaaa tgagtagata aagaggtaaa tgttatgcta
    30961 agatttccaa aggattttgt ctggggatcc tctacttctg gaccgcagac agaaggacgt
    31021 gtagctggtg acggtaaggg agacaatctc tgggattact ggttccaagt ggagccaaat
    31081 cgttactata atgggattgg ttcagataag acatcgactt tttatgaaaa ttgggagcgg
    31141 gatattgagc ttttgttaga gactggtcac acagtctttc ggacttctat tcagtggtca
    31201 cggatttttc cacaaggctg tggaaaagtc aaccctcaag gtgtggattt ttatcgtaag
    31261 gtctttgagg ctattaaggc taaaggaatt cgtctgttag tcaatctcta tcattttgat
    31321 ttaccttttg cccttcaaga ggatggtgat ggttgggaaa ataaggcgac agtctcagcc
    31381 tatgaagact atgctcgttt ttgttttgag acttatggag atttagtgga tcaatggatt
    31441 acctttaacg agcccatcgt tcctgtagaa tttggttatt tttatgatgc ccattatcca
    31501 cataaggtgg atgcagaggc agctgttaag gtagcctatc atacacaatt ggccagcagc
    31561 cgggctgtta aggcttgcca tgaacttttg cctgattcca agattgggat tgtcctcaac
    31621 ttgacaccgg cttatccacg tagccagcat cctgctgatg tcaaggcagc tcgtattgcg
    31681 gccctttttc aggcccaatc tttcttagat ccatctgtct tggggactta tccacaggag
    31741 ttggtagaaa tcttgcatga acacggtctt ttacctgatg ctacagagga agagttggaa
    31801 ctcattcatg ataatacggt ggacttcctt ggtgtgaact actatcaacc tttgcgtgtt
    31861 atggctcctc gatttgctaa gcatccagag agtccactct taccagaaca tttttacgag
    31921 ccttatgtga tgcctggacg taaaatcaat tctcaccgtg gttgggagat ttatgagcaa
    31981 gggatttatg acatcgccca aaatatcaag gaaaattatg gcaatattga atggatgttg
    32041 actgagaatg gtatgggtgt tgaaggggaa gaaaaattcc gtcaagatgg aatgattcaa
    32101 gatgattacc gtattgactt tgtaaaaggt catcttcgtg aacttcaccg tgccattgaa
    32161 gatggtgcca actgtaaggg ctacttgatt tggaccttta ttgactgctg gtcatggctc
    32221 aacagctata aaaatcgcta tggtttggtc gaattagact tggaaacgca agaacgtcgt
    32281 ctgaagaaat caggccactg gttcaaaaaa ttaagcgata ataatggatt ttaaaaagga
    32341 ctctgactga ttatcccaat cggtcagagt tttttgctta caggagctta atttgaacta
    32401 taccaatttt tactcttgac aagtgaaaga aacaagtata tactgttttt gctgattcta
    32461 taaaagatga attagactat accaatttta aggagaaagc acagcttgcc tgtgtcgtat
    32521 atactatgtg tggaattgtt ggtgttgttg gaaacacaaa tgcaactgat attttgattc
    32581 aagggcttga aaagcttgaa taccgtggct atgattctgc gggaattttt gtcctagatg
    32641 gtgctgataa ccatttggtg aaggctgttg gtcgtatcgc agaattgtct gccaagacag
    32701 ctggtgttga gggaacaact ggtatcggac atactcgttg ggcaactcat gggaaaccaa
    32761 cggaagacaa tgctcaccca caccgctctg agacagaacg ttttgtcttg gttcacaatg
    32821 gggtgattga aaactacctt gaaattaaag aagaatacct tgctgggcac cacttcaaag
    32881 ggcaaacaga tacggaaatc gccgtacatt tgattggaaa atttgcggaa gaagacggtc
    32941 tctcagttct tgaagccttt aaaaaagctc ttcatattat ccgtggttca tatgcctttg
    33001 ccttgattga ctctgaaaat ccagatgtca tctatgtagc gaaaaacaaa tctccacttt
    33061 tgattggtct tggggaaggc tacaatatgg tctgctcaga tgctatggct atgattcgtg
    33121 aaaccaacca atacatggaa attcatgacc aagagttggt aatcgtcaag gctgatagcg
    33181 tggaagttca agactatgat ggaaatcgtc gtgagcgtgc tagctacact gctgaacttg
    33241 acttgtcaga tatcggtaag ggaacttacc cttactacat gctcaaggaa attgacgagc
    33301 aaccaactgt tatgcggaaa ctcatccaag cctacacaga tgaggctggt caagttgtcg
    33361 tagacccaga tatcattaag gctgttcaag acgcagaccg catctacatc cttgcagctg
    33421 gaacatctta ccatgcagga tttgcttcta agaagatgtt ggaagaattg acagatacac
    33481 cagttgaact tggaatctca tctgagtggg gctacggtat gccacttctc agcaagaaac
    33541 cactcttcat ctttatcagc caatctggtg aaacagcgga tagtcgtcaa gttttggtca
    33601 aggctaatga aatgggaatt ccaagcttaa cagtgacaaa tgttccaggt tcaaccctct
    33661 cacgtgaagc caactatacc atgctccttc acgcaggtcc tgaaattgcc gtggcatcaa
    33721 ctaaagccta tacagcgcaa atcgcagccc ttgccttcct tgcaaaagca gtcggagaag
    33781 caaatggtaa tgctaaagcg caagcctttg acctggttca tgaattgtca atcgtagctc
    33841 agtctattga atcaactctt tcagagaaag aaaccattga agccaaggtt cgtgaacttc
    33901 ttgaaacaac tcgtaacgcc ttttacatcg gacgtggtca agattattac gtagccatgg
    33961 aagcaagtct caaactcaaa gagatttctt atatccagtg tgaaggtttt gcggcaggag
    34021 aactcaagca cggaaccatt gccttgattg aagaaggaac gcctgttttg gctctcttgt
    34081 cagatccagt tcttgccaac catactcgtg gaaatatcca agaggtcgca gcccgtggtg
    34141 ccaaagtcct cactatcgca gaagagaatg tagccaaaga taccgacgat atcgtcctta
    34201 cgaccgtaca tccatacctc tcaccaattt caatggtcgt accaacgcaa ttagtcgctt
    34261 actttgcaac cctccaccgt ggcctcgatg tggacaaacc acgtaacctt gccaagtcag
    34321 taacggtaga ataagctaaa aaagtctagt tatctaggct ttttcttgtg agcaaattgg
    34381 ttgcttgtac tcaagattcg tgttatactc ttagaaaatc tcttcaaacc acgtcaccgt
    34441 cgccttgccg taggtatggt tactga
//
LOCUS       DAVBDR010000016        33324 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.016, whole genome shotgun sequence.
ACCESSION   DAVBDR010000016 DAVBDR010000000
VERSION     DAVBDR010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 33324)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33324)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33324
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.016"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            <1..327
                     /locus_tag="VQ540_000811"
     CDS             <1..327
                     /locus_tag="VQ540_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine motif-containing protein"
                     /protein_id="HET2544638.1"
                     /translation="KPQTEKPEEETPREEKPQSEKPESPKPTEEPEEESPEESEEPQV
                     ETEKVEEKMREAEDLLGKIQDPIIKSNAKETLTGLKNNLLFGTQDNNTIMAEAEKLLA
                     LLKESK"
     gene            749..979
                     /locus_tag="VQ540_000812"
     CDS             749..979
                     /locus_tag="VQ540_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HET2544639.1"
                     /translation="MESIGIGLVIVSHSKHIAEGVVELISKVAKDVPITYVGGTEGGG
                     IGTSFDQVDRVVSENPADTLLAFFDLGSAIKC"
     gene            1383..2096
                     /locus_tag="VQ540_000813"
     CDS             1383..2096
                     /locus_tag="VQ540_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000499426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HET2544640.1"
                     /translation="MFYKFLLFDLDHTLLDFDAAEDVALTQLLKEEGVADIQAYKDYY
                     VPMNKALWKDLELKKISKQELVNTRFSRLFAHFGQEKDGSFLAQRYQFYLAQQGQTLS
                     GAHDLLDSLIERDYNLYAATNGITAIQTGRLAQSGLAPYFNQVFISEQLQTQKPDALF
                     YEKIGQQIAGFSKEKTLMIGDSLTADIQGGNNAGIDTIWYNPHHLENHTQAQPTYEVY
                     SYQDLLDCLDKNILEKITF"
     gene            2154..2756
                     /locus_tag="VQ540_000814"
     CDS             2154..2756
                     /locus_tag="VQ540_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2544641.1"
                     /translation="MSEVDFNEAVNYEFTSDTCQLANSIYQSLFKFFDKKNFSGDLIF
                     TWKSPSLVKEGDYIGRRDSQVDNLRVIGNIFPNYLTNRKYSLNMNRNGCMGDFPHDFF
                     DIYLDHVAKYAYEQKVNNIKEYYPLKRAILHQENALYFRFFSNFDDFLEKNYLKTIWQ
                     VSKETPFSEMDFNMFKNISEKIIFERGSKMLNDLKSNYKK"
     gene            2892..3545
                     /locus_tag="VQ540_000815"
     CDS             2892..3545
                     /locus_tag="VQ540_000815"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HET2544642.1"
                     /translation="MEHSSWHALIKAQLPEGYFGKINQFMEQVYSQGIIYPPKEKVFQ
                     ALLTTLLEEVKVVILGQDPYHGPGQAQGLSFSVPDSIPAPPSLQNILKELSDDIGVKK
                     SHDLTAWAEQGVLLLNACLTVPAGQANGHAGQIWEPFTDAVIQVVNHLDRPVVFVLWG
                     AYARKKKALVTNPHHLIIESAHPSPLSVYRGFWGSKPFSKANAFLKETGQEPIDWLR"
     gene            3555..4019
                     /locus_tag="VQ540_000816"
     CDS             3555..4019
                     /locus_tag="VQ540_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003012002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HET2544643.1"
                     /translation="MPQLATICYIDNGKELLMLHRNKKPNDVHEGKWIGVGGKLERGE
                     TPQECAAREILEETGLKAKPVLKGVITFPEFTPDLDWYTYVFKVTEFEGDLIDCNEGT
                     LEWVPYDEVLSKPTWEGDHTFVEWLLEDKPFFSAKFVYDGDKLLDTQVDFYE"
     gene            4032..5300
                     /locus_tag="VQ540_000817"
     CDS             4032..5300
                     /locus_tag="VQ540_000817"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HET2544644.1"
                     /translation="MLLIKNGRVMDPKSGLDQVCDVLVQDGKIIKIAPEITEEGAETI
                     DATGLVVAPGLVDIHVHFREPGQTHKEDIHTGALAAAAGGFTTVVMMANTSPTISDVE
                     TLQAVLQSAAKEKINVKTVATITKNFNGKNLTDFKALLEAGAVGFSDDGIPLESSKIV
                     KEAMEEAKKLNTFISLHEEDPGLNGVLGFNENIAREHFHICGATGVAEYAMMARDVMI
                     AYATKAHVHIQHLSKEESVKVVEFAQGLGAEVTAEVAPQHFSKTEALLLTQGSNAKMN
                     PPLRLESDRRAVIEGLKSGVITVIATDHAPHHVDEKNVEDITKAPSGMTGLETSLSLG
                     LTYLVEAGELSLMELLEKMTYNPAKLYNFEAGYLAENGPADITIFDAKADRLVDSHFA
                     SKAANSPFIGETLKGQVKYTICKGQIVYQA"
     gene            5314..5574
                     /locus_tag="VQ540_000818"
     CDS             5314..5574
                     /locus_tag="VQ540_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2544645.1"
                     /translation="MNYFRKRRERQAKSNSGIYCPAANRSKIQYETKEKADHAVQYDN
                     GGLVRSYYCRTCACWHTTSKSNKPPLSLKNYGLKLFGLDKSE"
     gene            5585..6946
                     /gene="pdrM"
                     /locus_tag="VQ540_000819"
     CDS             5585..6946
                     /gene="pdrM"
                     /locus_tag="VQ540_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-coupled multidrug efflux MATE transporter
                     PdrM"
                     /protein_id="HET2544646.1"
                     /translation="MYKTKCLREKLVLFLKIFFPILIYQFANYSASFVDTAMTGQYNT
                     MDLAGVSMATSIWNPFFTFLTGIVSALVPIIGHHLGRGKKEEVASDFYQFIYLALGLS
                     VVLLGMVLFLAPTILNHIGLEAAVAAVAVRYLWFLSIGIIPLLLFSVIRSLLDSLGLT
                     KLSMYLMLLLLPLNSGFNYLLIYGAFGVPELGGAGAGLGTSLAYWVLLGISVLVLFKQ
                     EKLKALHLEKRIPLNMDKIKEGVRLGLPIGGTVFAEVAIFSVVGLIMAKFSSLIIASH
                     QSAMNFSSLMYAFPMSISSAMAIVVSYEVGAKRFDDAKTYIGLGRWTALIFAAFTLTF
                     LYIFRGNVASLYGNDPKFIDLTARFLTYSLFFQLADTFAAPLQGILRGYKDTVIPFYL
                     GLLGYWGVAIPVATLFDSLTDFGAYSYWIGLIISLIVSGALYRWRLTVIMKRFESLAK
                     SKR"
     gene            7100..8068
                     /locus_tag="VQ540_000820"
     CDS             7100..8068
                     /locus_tag="VQ540_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent dehydrogenase
                     E1 component subunit alpha"
                     /protein_id="HET2544647.1"
                     /translation="MSTLDKNLLLEMFRKMEEIRRMDLKIAQLVKKGKVPGMTHFSVG
                     EEAANVGAMLALNPDDLITSNHRGHGQAIAKGIDLNGMMAEILGKYTGTCKGKGGSMH
                     IADLDAGNLGANGIVGGGMGIAVGAALSQQMQNTGKIVVCFFGDGATNEGVFHEAVNM
                     ASIWNLPVIFYCINNGYGISADIKKMTNIEHIHQRSAAYGIPGMFIEDGNNVIDVYEG
                     FQKAVDHVRSGNGPVLIESVTYRWLGHSSSDPGKYRTREEVELWKQKDPIENLRNYLI
                     ENNIASAEELEEIQAQVKEAVEASVKFAEESPFPPLESAFEDIYAD"
     gene            8084..9076
                     /locus_tag="VQ540_000821"
     CDS             8084..9076
                     /locus_tag="VQ540_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000448722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HET2544648.1"
                     /translation="METKTMSFRDTIILAMSEEMRRDENVFLMGEDVGVFGGDFGTSV
                     GMLEEFGPERVRDCPISEAAISGAAAGAAMTGLRPIVDMTFMDFSVIAMDNIVNQAAK
                     TRYMFGGKGQVPMTVRCAAGNGVGSAAQHSQSLESWFTHIPGLKVVAPGTPADMKGLL
                     KSSIRDKNPVIILEYKSEFNQKGEVPVDPDYTIPLGVGEIKRQGTDVTVVTYGKMLRR
                     VVQAAEELAEEGISVEIVDPRTLVPLDKDIIINSVKKTGKVVLVNDAHKTSGYISEIS
                     AIISESEAFDYLDAPIRRCAGEDVPMPYAQNLENAMIPTVESIKDAIRKTYNKE"
     gene            9294..10337
                     /locus_tag="VQ540_000822"
     CDS             9294..10337
                     /locus_tag="VQ540_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide acetyltransferase"
                     /protein_id="HET2544649.1"
                     /translation="MADDKLRATPAARKLADDLGINLYDVSGSGANGRVHKEDVETYK
                     DTNVVRISPLAKRIALEHNIAWQEIQGTGHRGKIMKKDVLALLPENIENDSIKSPAQI
                     EKVEEVPDNVTPYGEIERIPMTPMRKVIAQRMVESYLTAPTFTLNYEVDMTEMLALRK
                     KVLEPIMEATGKKTTVTDLLSLAVVKTLMKHPYINASLTEDGKTIITHNYVNLAMAVG
                     MDNGLMTPVVYNAEKMSLSELVVAFKDVIGRTLDGKLAPSELQNSTFTISNLGMFGVQ
                     SFGPIINQPNSAILGVSSTIEKPVVVNGEIVIRPIMSLGLTIDHRVVDGMAGAKFMKD
                     LKELIETPISMLI"
     gene            10401..12086
                     /gene="lpdA"
                     /locus_tag="VQ540_000823"
     CDS             10401..12086
                     /gene="lpdA"
                     /locus_tag="VQ540_000823"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HET2544650.1"
                     /translation="MPKAGVDMTEGQIVQWNKKVGEFVKEGEILLEIMTDKVSMELEA
                     EEDGYLIAILKGDGETVPVTEIIGYLGEERENIPTAGAASPEASPVPVASTSNDDGKS
                     DDAFDIVVIGGGPAGYVAAIKAAQLGGKVALVEKSELGGTCLNRGCIPTKTYLHNAEI
                     IENIGHAANRGIVIENPNFTVDMEKLLETKSKVVNTLVGGVAGLLRSYGVTVHKGIGT
                     ITKDKNVLVNGSELLETKKIILAGGSKVSKINVPGMQSPLVMTSDDILEMNEVPESLV
                     IIGGGVVGIELGQAFMTFGSKVTVIEMMDRIVPAMDAEVSKNLRLILERKGMTILTGT
                     KLQEIIEENGQLRIKVEGKDDIIASKALLSIGRMPDLEGIGEVEFELDRGCIKVNEYM
                     ETSVPGIYAPGDINGTKMLAHAAFRMGEVSAENALKGNHAVAKLNLTPAAIYTLPEVA
                     AVGLTEEQAREKYDVAIGKFNFAANGRAIASDAAQGFVKVIADKKYGEIIGVHIIGPA
                     AAELINEASSIIEMEITVEEMLKTIHGHPTYSEVMYEAFADVLGMAIHSPKKK"
     gene            12150..13139
                     /locus_tag="VQ540_000824"
     CDS             12150..13139
                     /locus_tag="VQ540_000824"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000873976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HET2544651.1"
                     /translation="MKYIINHSNDTAFNIALEEYAFKHLLDEDQIFLLWINKPSIIVG
                     RHQNTIEEINRDYVRENGIEVVRRISGGGAVYHDLNNLNYTIISKEDENKAFDFKSFS
                     TPVINTLAQLGVKAEFTGRNDLEIDGKKFCGNAQAYINGRIMHHGCLLFDVDLSVLAN
                     ALKVSKDKFESKGVKSVRARVTNIINELPKKITVEKFRDLLLEYMKKEYPEMTEYVFS
                     EEELAEINHIKDTKFGTWDWNYGKSPEFNVRRGTKFTSGKVEVFANVTESKIQDIKIY
                     GDFFGIEDVAAVEDVLRGVKYEREDVLKALKTIDITRYFAGISREEIAEAVVG"
     gene            complement(13206..14276)
                     /gene="xerS"
                     /locus_tag="VQ540_000825"
     CDS             complement(13206..14276)
                     /gene="xerS"
                     /locus_tag="VQ540_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000817875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HET2544652.1"
                     /translation="MKREILLERIDKLKQLMPWYVLEYYQSKLAVPYSFTTLYEYLKE
                     YDRFFSWVLESGISNADKISDIPLSVLENMSKKDMESFILYLRERPLLNANTTKQGVS
                     QTTINRTLSALSSLYKYLTEEVENDQGEPYFYRNVMKKVSTKKKKETLAARAENIKQK
                     LFLGDETEGFLTYIDQEHPQQLSNRALSSFNKNKERDLAIIALLLASGVRLSEAVNLD
                     LRDLNLKMMVIDVTRKGGKRDSVNVAAFAKPYLENYLAIRNQRYKTEKTDTALFLTLY
                     RGVPNRIDASSVEKMVAKYSEDFKVRVTPHKLRHTLATRLYDATKSQVLVSHQLGHAS
                     TQVTDLYTHIVNDEQKNALDSL"
     gene            complement(14860..16410)
                     /locus_tag="VQ540_000826"
     CDS             complement(14860..16410)
                     /locus_tag="VQ540_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HET2544653.1"
                     /translation="MEEQSEIVRSKKEFAFASSTILSQVGRGIIVGLIVGIIVGSFRF
                     LIEKGFHLIQGVYQDQGYLVRNLFVLVLFYILICWLSAKLTRSEKDIKGSGIPQVEAE
                     LKGLMSLNWWGILWKKYVLGILAIASGLMLGREGPSIQLGAVGGKGIAKWLKSSPVEE
                     RSLIASGAAAGLAAAFNAPIAALLFVVEEVYHHFSRFFWVSTLAASIVANFVSLLMFG
                     LTPVLDMPDNIPPMTLDQYWIYLVMGIFLGFSGFLYEKAVLNVGRVYDLIGQKIHLDR
                     AYYPILAFIIIIPVGIFLPQIIGGGNQLVLSLTEQNFSFQVLLAYFLIRFIWSMISYG
                     SGLPGGIFLPILALGSLLGSLVGVICVNLGLVSQEQFPIFVILGMSGYFGAISKAPLT
                     AMILVTEMVGDIRNLMPLGLVTLVSYIIMDLLKGTPVYEAMLEKMLPEEVSSEGEVTL
                     IEIPVSDKIAGKQVHELNLPHNVLITTQVHNGKSQTVNGSTRMYLGDMIHLVIPKSEI
                     GKVKDLLL"
     gene            complement(16426..17205)
                     /locus_tag="VQ540_000827"
     CDS             complement(16426..17205)
                     /locus_tag="VQ540_000827"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HET2544654.1"
                     /translation="MATIKEIKELLVTVKELESPIFLDLEKDNRSGVQKEISKHKRAI
                     QAELDENLRLESMLSYEKELYKQGLTLIAGIDEVGRGPLAGPVVAAAVILPKNCKIKG
                     LNDSKKIPKKKHLEIFQVVQDQALSIGIGIIDNQVIDQVNIYEATKLAMQEAISQLSP
                     QPEHLLIDAMKLDLPISQTSIIKGDANSLSIAAASIVAKVTRDELMKEYDQQFPGYDF
                     ATNAGYGTAKHLEGLTKLGVTPIHRTSFEPVKSLVLGKKES"
     gene            complement(17192..18043)
                     /gene="ylqF"
                     /locus_tag="VQ540_000828"
     CDS             complement(17192..18043)
                     /gene="ylqF"
                     /locus_tag="VQ540_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HET2544655.1"
                     /translation="MATIQWFPGHMSKARRQVQENLKFVDFVTILVDARLPLSSQNPM
                     LTKIVGDKPKLLILNKADLADPAMTKEWRQYFESQGIQTLAINSKEQVTVKVVTDAAK
                     KLMADKIARQKERGIQIETLRTMIIGIPNAGKSTLMNRLAGKKIAVVGNKPGVTKGQQ
                     WLKTNKDLEILDTPGILWPKFEDETVALKLALTGAIKDQLLPMDEVTIFGINYFKEHY
                     PEKLAERFKQMKIEEEAPVIIMDMTRALGFRDDYDRFYSLFVKEVRDGKLGNYTLDTL
                     EGLDGND"
     gene            complement(18250..18426)
                     /locus_tag="VQ540_000829"
     CDS             complement(18250..18426)
                     /locus_tag="VQ540_000829"
                     /inference="COORDINATES: protein motif:HMM:NF012948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HET2544656.1"
                     /translation="MQAGIPTDNEVSYALIYQQETLPATGSSTSALTALGLLAVGSLV
                     LLVHNMTGTVFCSL"
     gene            complement(18478..24369)
                     /gene="iga"
                     /locus_tag="VQ540_000830"
     CDS             complement(18478..24369)
                     /gene="iga"
                     /locus_tag="VQ540_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunoglobulin A1 protease"
                     /protein_id="HET2544657.1"
                     /translation="MEKYFGEKQERFSFRKLSVGLVSATISSLFFMSVLASSSVDAQE
                     TAGVHYKYVADSELSSEEKKQLVYDIPTYVENDDETYYLVYKLNSQNQLAELPNTGSK
                     NERQALVAGASLAALGILIFAVSKKKVKNKTVLHLVLVAGMGNGVLVSVHALENHLLL
                     NYNTDYELTSGEKLPLPKEISGYTYIGYIKEGKTTSDFEVSNQEKSAATPTKQQKVDY
                     NVTPNFVDHPSTVQAIQEQTPVSSTKPTEVQVVEKPFSTELINPRKEEKQSSDSQEQL
                     AEHKNLETKKEEKISPKEKTGVNTLNPQDEVLSGQLNKPELLYREETIETKIDFQEEI
                     QENPDLAEGTVRVKQEGKLGKKVEIVRIFSVNKEEVSREIVSTSTTAPSPRIVEKGTK
                     KTQVIKEQPETGVEHKDVQSGSIVEPAIQPELPEAVVSDKGEPEVQPTLPEAVVTDKG
                     ETEVQPESPDTVVSDKGEPEQVAPLPEYKGNIEQVKPETPVEKTKEQGPEKTEEVPVK
                     PTEETPVNPNEGTTEGTSIQEAENPVQPAEESTTNSEKVSPDTSSENTGEVSSNPSDS
                     TTSVGESNKPEHNDSKNENSEKTVEEVPVNPNEGTVEGTSNQETEKPVQPAEETQTNS
                     GKIANENTGEVSNKPSDSKPPVEESNQPEKNGTATKPENSGNTTSENGQTEPEKKLEL
                     RNVSDIELYSQTNGTYRQHVSLDGIPENTDTYFVKVKSSAFKDVYIPVASITEEKRNG
                     QSVYKITAKAEKLQQELENKYVDNFTFYLDKKAKEENTNFTSFSNLVKAINQNPSGTY
                     HLAASLNANEVELGPDERSYIKDTFTGRLIGEKDGKNYAIYNLKKPLFENLSGATVEK
                     LSLKNVAISGKNDIGSLANEATNGTKIKQVHVDGVLAGERGVGGLLAKADQSSIAESS
                     FKGRIVNTYETTDAYNIGGLVGHLTGKNASIAKSKATVTISSNTNRSDQTVGGLAGLV
                     DQDAHIQNSYAEGDINNVKHFGKVAGVAGYLWDRTSGEEKHAGELTNVLSDVNVTNGN
                     AITGYHYTGMKVANTFSSKANRVFNVTLEKDEVVSKESFEERGTMLDASQIVSKKAEI
                     NPLTLPTVEPLSTSGKKDSDFSKIAHYQANRALVYKNIEKLLPFYNKSTIVKYGNLVK
                     ENSLLYQKELLSAVMMKDDQVITDIVSNKQTANKLLLHYNDHSSEKFDLKYQTDFANL
                     AEYNLGNTGLLYTPNQFLYDRDSIVKEVLPELQKLDYQSDAIRKTLGISPEVKLTELY
                     LEDQFSKTKQNLGDSLKKLLSADAGLASDNSVTRGYLVDKIKNNKEALLLGLTYLERW
                     YNFNYGQVNVKDLVMYHPDFFGKGNTSPLDTLIELGKSGFNNLLAKNNVDTYGISLAS
                     QHGTTDLFSTLEHYRKVFLPNTSNNDWFKSETKAYIVEEKSTIEEVKTKQGLAGTKYS
                     IGVYDRITSATWKYRNMVLPLLTLPERSVFVISTMSSLGFGAYDRYRSSDHKAGKALN
                     DFVEENARETAKRQRDHYDYWYRILDEQSREKLYRTILLYDAYKFGDDTTSGKATAEA
                     KFDSSNPAMKNFFGPVGNKVVHNQHGAYATGDGVYYMSYRMLDKDGAITYTHEMTHDS
                     DQDIYLGGYGRRNGLGPEFFAKGLLQAPDQPSDATITINSILKHSKSDSTEGSRLQVL
                     DPTERFQNAADLQNYVHNMFDLIYMMEYLEGQSIVNKLSVYQKMAALRKIENKYVKDP
                     ADGNEVYATNVVKELTEAEARNLNSFESLIDHNILSAREYQSGDYERNGYYTIKLFAP
                     IYSALSSEKGTPGDLMGRRIAYELLAAKGFKDGMVPYISNQYEEDAKQQGQTINLYGK
                     ERGLVTDELVLKKVFDGKYKTWAEFKTAMYQERVDQFGNLKQVTFKDPTKPWPSYGTK
                     TINNVDELQALMDQAVLKDAEGPRWSNYDPEIDSAVHKLKRAIFKAYLDQTNDFRSSI
                     FENKK"
     gene            complement(24578..25756)
                     /locus_tag="VQ540_000831"
     CDS             complement(24578..25756)
                     /locus_tag="VQ540_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2544658.1"
                     /translation="MTLPVRKSLHDAVLQASKADTWEQATKEWNEVSLIFNGIGRSNC
                     VCRNAIKYAYELFNGVTGQRLFPIGSDCVRHFHRLPLDQQLEEEEKLLRKVENLTRKA
                     QKKEKIKVNKSDFDERLLKWLWEKGVFKPNRGNQFAPERDYQLFLEVFQGGSWTKAEP
                     KKKARMEEVLEKCIKPFLLGKSDDQLYLVKLGKEKIDYEQELRIQAEKERKKRDKIAK
                     QYADNLVLAMGPAERAYQDYFGFTETLTQEERKWEKILFGKNRAERAIKAKQYQKELE
                     KDQRIASQDPIERKQKQTWILNSYFRELPEEKARFSRLLLEYRKSGEVPFSTEYLSDH
                     LIDFFYKMKAFEFEIAPEQVRDFLKKSLQEDHRSSAQGSWIEGILLNCLKPFLERLVI
                     "
     gene            complement(25926..29576)
                     /gene="addA"
                     /locus_tag="VQ540_000832"
     CDS             complement(25926..29576)
                     /gene="addA"
                     /locus_tag="VQ540_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HET2544659.1"
                     /translation="MKLIPFLSEEEIQKLQEAEANSSKEQKKTAEQIEAIYTSGQNIL
                     VSASAGSGKTFVMAERILDQLARGVEISQLFISTFTVKAATELKERLEKKISKKIQET
                     DDVDLKQHLGRQLADLPNAAIGTMDSFTQKFLGKHGYLLDIAPNFRILQNQSEQLLLE
                     NEVFHEVFEAHYQGKQKETFSHLLKNFAGRGKDERGLRQQVYKIYDFLQSTSNPQKWL
                     SESFLKGFEKADFTSEKEKLTEQIKQALWDLESFFRYHLDNDAKEFAKAAYLENVQLI
                     LDEICSLNQESDSQAYQAVLARVVAISKEKNGRALTNASRKADLKPLADAYNEERKTQ
                     FAKLGQLSDQITILDYQERYHQDTWKLAKTFQTFMSHFVEAYRQRKRQENAFEFADIS
                     HYTIEILENFPQVRESYQERFHEVMVDEYQDTNHIQERMLELLSNGHNRFMVGDIKQS
                     IYRFRQADPQIFNEKFQRYAQNPQEGKLILLKENFRSSSEVLSATNDVFERLMDQEVG
                     EINYDNKHQLVFANTKLTPNPDNKAEFLLYDKDDTGEEEESQTETKLTGEMRLVIKEI
                     LKLHQEKGVAFKEIALLTSSRSRNDQILLALSEYGIPVKTDGEQNNYLQSLEVQVMLD
                     TLRVIHNPLQDYALVALMKSPMFGFDEDELARLSLQKAEDKVHENLYEKLVNAQKMAS
                     SQKGLIHTALVEKLKQFMDILASWRLYAKTHSLYDLIWKIYNDRFYYDYVGALPNGPA
                     RQANLYALALRADQFEKSNFKGLSRFIRMIDQVLEAQHDLASVAVAPPKDAVELMTIH
                     KSKGLEFPYVFILNMDQDFNKQDSMSEVILSRQNGLGVKYIAKMETGAVEDHYPKTIK
                     LSIPSLTYRQNEEELQLASYSEQMRLLYVAMTRAEKKLYLVGKGSREKLESKEYPAAK
                     NGKLNSNTRLQARNFQDWLWAISKVFTKDKLNFSYRFIDEDQLTREAIGELETKSPLQ
                     DSSQADNRQSDTIKEALEMLKEVEVYNTLHRAAIELPSVQTPSQIKKFYEPVMDMEGV
                     EIAGQGQSVGKKISFDLPDFSTKEKVTGAEIGSATHELMQIIDLSQQLTLASLTETLK
                     QVQTSQAVRDKINLDKILAFFDTALGQEILANTDHLYREQPFSMLKRDQKSQEDFVVR
                     GILDGYLLYENKIVLFDYKTDRYDEPSQLVDRYRGQLALYEEALSRAYSIENIEKYLI
                     LLGKDEVQVVKV"
     gene            complement(29573..32848)
                     /gene="rexB"
                     /locus_tag="VQ540_000833"
     CDS             complement(29573..32848)
                     /gene="rexB"
                     /locus_tag="VQ540_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent nuclease subunit B"
                     /protein_id="HET2544660.1"
                     /translation="MKLLYTDIRTSLTEILTREAEELVAAGKRVFYIAPNSLSFEKER
                     AVLECLSQQASFSITVTRFAQMARYLVLNDLPVKTTLDDIGLGLAFYKCLAELDPKDL
                     RVYGAIKQDPQLIQQLIELYHEMTKSQMSFLDLENLTDEDKRADLLLIFEKVTAYLNQ
                     GQLAQGSQLSHLIEAIENDKVSSDFNQITLVIDGFTRFSAEEERVVDLLHGKGVEIVI
                     GAYASKKAYTSPFSEGNLYQASVKFLHHLASKYQTPAQDCSQTHEKMDSFDKASRLLE
                     SSYDFSELALDVDEKDRENLQIWSCLTQKEELELVARSIRQKLHENSDLSYKHFRILL
                     GDVASYQLSLKTIFDQYQIPFYLGRSEAMAHHPLTQFVESILALKRYRFRQEDLINLL
                     RTDLYTDLSQSDIDAFEQYIRYLGINGLPAFQQTFTKSHHGKFNLERLNVLRLRILAP
                     LETLFASRKQKAENLLQKWSVFLKEGAVTKQLQDLTTTLEAVEQERQAEVWKAFCHVL
                     EQFATVFAGSQVSLEDFLALLHSGMSLSQYRTIPATVDTVLVQSYDLIAPLTADFVYA
                     IGLTQDNLPKISQNTSLLTDEERQNLNQTTEEGVQLLIASSENLKKNRYTMLSLVNSA
                     RKQLFLSAPSLFNESESKESAYLQELIHFGFRRREKRMNHKGLSKEDMGSYHSLLSSL
                     VAYHQQGEMSDTEQDLTFVKVLSRVIGKKLDQQGLENPAIPISPSSKTLAKDTLQALY
                     PAKQEFYLSTSGLTEFYRNEYSYFLRYVLGLQEELRLRPDARSHGNFLHRIFERALQL
                     PNEDSFDQRLEQAIQETSQEREFEAIYQESLEAQFTKEVLLDVARTTGHILRHNPAIE
                     TIKEEANFGGKDQAFIQLDNGRSVFVRGKVDRIDRLKANGAIGVVDYKSSLTQFQFPH
                     FFNGLNSQLPTYLAALKREGEQNFFGAMYLEMAEPVQSLMAVKSLAGAVVEASKSMKY
                     QGLFLEKESSYLGEFYNKNKANQLTDEEFQLLLDYNAYLYKKAAEKILAGRFAINPYT
                     ENGRSIAPYVQQHQAITGFEANYHLGQARFLEKLDLADGKRLVGEKLKQAWLEKIREE
                     LNR"
     gene            complement(33048..33203)
                     /locus_tag="VQ540_000834"
                     /pseudo
     CDS             complement(33048..33203)
                     /locus_tag="VQ540_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
BASE COUNT         9515 a         6539 c         6861 g        10409 t
ORIGIN      
        1 aaacctcaga cagaaaaacc tgaggaagaa acccctcgag aagagaaacc gcaaagcgag
       61 aaaccagagt ctccaaaacc aacagaggaa ccagaagaag aatcaccaga ggaatcagaa
      121 gaacctcagg tcgagactga aaaggttgaa gaaaaaatga gagaggctga agatttactt
      181 ggaaaaatcc aggatccaat tatcaagtcc aatgccaaag agactctcac aggattaaaa
      241 aataatttac tatttggcac ccaggacaac aatactatta tggcagaagc tgaaaaacta
      301 ttggctttat taaaggagag taagtaaagg tagcagcatt ttctaactcc taaaaacagg
      361 ataggagaac gggaaaacga aaaatgagag cagaatgtga gttctagttc tcattttttt
      421 catgaaaatg tgcaaaatat agtagattga aactagaata gtatacctct acttctaaaa
      481 cattgttaga aatcgatttg actgtcctgt tcttatttca ttttactata tcttaacaga
      541 tagtgtaaat aaagataaac tatttactgg ctaattaatc agttaaacac tagttaagga
      601 gtaatgatga aaaaaagaac aatactatta ttgatggcca gtctgttagc tcttgtctta
      661 ggagcatgtg gtttcttgga catattgatc ctggatcatt ctcatcagga ttactcttta
      721 ctgctatttt agaaactggg gtggtttgat ggaaagtatt ggtattggtc ttgttatcgt
      781 ttcacattcc aaacacattg cagaaggtgt tgttgaactg attagtaaag tagctaaaga
      841 tgttccgatt acttatgtag gaggaaccga gggcggagga attggaacga gttttgatca
      901 agtagatagg gttgtttccg aaaatccagc agatacttta cttgcctttt ttgacctagg
      961 ttctgctata aaatgttaag taaatgattt caaaatcaga aagggattgc tttgggcagt
     1021 tcctttttaa tgtaaatgta aaaggagtag aatcatagtg tttctaaatt gtgaatcaat
     1081 caaaactgat tgtgatgggg ctattctagc tttagaatcc ttcaaaaatt aaaatttaag
     1141 gcaatcaatt acttggaaga gtatgaaagc atttagttta taggaattct aggcctagaa
     1201 ttacatatgt atttatgaag ataggggtgt tcgatagtta gtattgttct gttctgaaag
     1261 atttgagctg tcagttgtat agaaagtgtt cgaatttttt ttaagtgatt aaattagtta
     1321 attgtatgag gttctttatg atataatgtt cttaatgaat tttcagaaag gaaaacctca
     1381 aattgttcta caaatttcta ctcttcgacc tcgaccacac tcttcttgat tttgatgctg
     1441 ctgaggatgt ggctttgacc caacttctaa aagaagaagg agttgcggat attcaggctt
     1501 ataaagatta ttacgttcct atgaacaagg ctctctggaa agacttggag ctgaagaaaa
     1561 tcagtaaaca agagctggtt aacacgcgct tttctcgttt atttgctcat tttggacagg
     1621 aaaaagacgg tagttttctt gcccagcgtt accaatttta cctcgcccag cagggacaaa
     1681 cactatcggg cgctcatgat ctcttggaca gcctcattga gcgtgattat aacttgtatg
     1741 ctgcgacaaa tggcattact gccattcaga caggacgttt ggctcaatct ggtctagcac
     1801 cttatttcaa tcaagtcttt atctcagaac agttgcaaac tcaaaagccg gatgctctct
     1861 tttatgaaaa gattggccag caaattgctg gatttagtaa agaaaagacg ctgatgattg
     1921 gagattctct aaccgccgac attcaaggtg gcaataatgc ggggattgat actatctggt
     1981 ataatcctca tcacctcgaa aatcacacac aagcccagcc gacttacgaa gtctattctt
     2041 accaagactt gctggattgt ttagataaaa atattcttga aaagatcaca ttttaaagga
     2101 gacgagctaa tgactacaaa aaagctaata ttactattga agagtacatt gaaatgtctg
     2161 aagttgattt taatgaagct gttaattatg aatttacatc tgacacttgt caattagcaa
     2221 atagtattta tcaatctctt tttaagtttt ttgataagaa aaatttctct ggcgatttaa
     2281 tttttacttg gaaatctcca tcattagtca aagaagggga ttatattggg agaagggatt
     2341 cacaagtaga taatcttaga gtaataggaa atatatttcc gaattatctt actaatcgaa
     2401 aatatagcct caatatgaat cgtaatggct gtatgggaga ttttcctcat gacttttttg
     2461 atatatacct agatcatgta gcaaaatatg cctacgaaca aaaagttaat aatattaaag
     2521 agtattatcc tttaaaaaga gcgattttac accaagagaa tgcattgtat tttcgatttt
     2581 tttctaattt tgacgacttt ttagaaaaaa attatttaaa gactatatgg caagtttcta
     2641 aagaaactcc tttttctgaa atggatttta atatgtttaa aaatatttca gaaaagataa
     2701 tcttcgaaag aggtagtaaa atgcttaatg atttaaaaag taattataaa aaatagccag
     2761 tctttataaa ctgtattcac gtattcaaat cgtatatagt cgatttatta aatctttaga
     2821 taaactgtaa aaagtggttt ccatagccac tttttgctat aatagaggca gtaaaaatga
     2881 aggagtcggc tatggaacac tcgtcttggc atgctttgat taaggcgcaa ttacctgagg
     2941 gttatttcgg gaaaatcaat cagtttatgg agcaggtcta ttctcagggg attatttatc
     3001 cacccaagga aaaggttttt caggctctct tgacaacact gcttgaagaa gttaaggtgg
     3061 taattctagg gcaagacccc tatcacggac caggtcaagc gcagggcttg agtttttctg
     3121 tacctgactc tatcccagct ccaccatcct tgcaaaatat cttgaaagaa ttgtcagatg
     3181 atatcggagt taagaaatct catgatttga cagcttgggc tgagcaagga gtcttgcttc
     3241 ttaatgcttg tttgactgtt cctgctggac aggccaatgg tcatgctggt caaatctggg
     3301 agccttttac tgatgctgtg attcaggtgg tcaatcatct agatagacca gtcgtttttg
     3361 tactctgggg agcttatgca cgtaagaaga aggccttagt taccaatcct catcacttga
     3421 ttatcgaatc agcccatcca agtcctttgt cggtttatag aggattttgg ggttccaagc
     3481 ccttttccaa ggccaatgca ttcttaaaag agacaggaca agagccaatc gattggctta
     3541 gataaggaga aaatatgcct cagttagcga cgatttgcta cattgataat gggaaagaac
     3601 tgctcatgct ccatcgtaat aagaaaccca atgatgtcca tgaagggaaa tggattggtg
     3661 tgggtggtaa gctagagaga ggagagacgc cccaggaatg cgcggcgcgt gaaatccttg
     3721 aagaaacagg gctcaaagcc aagccagttc taaaaggtgt catcactttt cctgaattta
     3781 caccagattt agactggtac acctatgttt ttaaggtgac ggagtttgag ggcgacttga
     3841 ttgactgcaa tgaggggacg ctagaatggg ttccctatga cgaggttttg agcaagccga
     3901 cttgggaagg tgaccacacc tttgttgagt ggcttttaga ggataaaccc ttcttttcag
     3961 ccaagtttgt ttatgatggg gataaattgt tggataccca agttgatttc tatgaataaa
     4021 ggagaaagca gatgctacta atcaaaaatg gtcgtgtaat ggatcctaag tctggtttgg
     4081 atcaagtttg tgatgtctta gttcaagatg ggaaaattat caaaattgcg cctgagatca
     4141 cggaagaagg agcagaaacg attgatgcta ctggtcttgt ggttgctcct ggtttggtcg
     4201 atattcatgt gcatttccgt gaacctggtc aaacacataa agaagacatt catactggtg
     4261 ccctggcagc cgctgcaggt ggttttacta ctgtcgtcat gatggctaat accagtccaa
     4321 ccatttcaga cgtggagact ttgcaagcag ttctccagtc agctgccaaa gagaagatta
     4381 atgtcaagac agttgcgacc attactaaaa actttaatgg taaaaacttg actgacttta
     4441 aggcgctctt agaagctggt gcggttggtt tctctgatga cggtattccg cttgagagca
     4501 gtaagattgt caaggaagcc atggaggaag ccaaaaaact caataccttt atcagccttc
     4561 atgaggaaga tccaggtttg aacggtgttc ttggctttaa tgaaaatatt gctagagaac
     4621 atttccatat ctgcggtgct actggggtgg ctgagtacgc tatgatggcg cgtgatgtca
     4681 tgattgccta tgcaactaaa gcccatgttc acatccagca tttgtctaag gaagaaagtg
     4741 ttaaagtagt ggagtttgct caggggttag gtgcagaagt cacagcagaa gtagcgccac
     4801 agcatttctc taagacagaa gcacttcttt taacacaagg tagcaatgct aagatgaatc
     4861 caccgcttcg tttggaatca gaccgtcgtg ccgttatcga aggtctcaaa tcaggtgtca
     4921 tcacagttat tgcgactgac cacgcgcctc atcatgtaga tgaaaaaaat gttgaggata
     4981 ttaccaaagc gccatctggt atgactggct tagaaacatc cctgtctctc ggcttgacct
     5041 atttagtaga agctggtgag ttgagcttga tggaattact tgaaaaaatg acatacaacc
     5101 cagccaagct ttacaacttt gaagcaggtt acttggctga gaatggtcca gcagatatca
     5161 ctatttttga tgccaaggct gaccgccttg tggactccca ttttgcttcc aaagcagcta
     5221 attcaccatt catcggtgaa accttaaaag ggcaggttaa atataccatc tgtaagggac
     5281 aaatcgtcta tcaagcttga taggagttag aatatgaatt attttcgaaa acgtagggag
     5341 agacaagcga aatctaatag tggaatttac tgtcccgcag ctaatcgttc caaaattcaa
     5401 tatgaaacta aagaaaaagc tgaccatgcg gttcaatatg ataacggagg tttagttaga
     5461 agctattatt gtcgtacatg tgcgtgttgg catactactt caaaatctaa taaacctccg
     5521 ctaagtttga aaaactatgg tctgaaactc tttggtttag ataaatcaga atagaaagag
     5581 aagtatgtat aagacaaagt gtttacgaga gaagttagta ttatttttaa aaattttctt
     5641 cccaatcctg atctaccaat ttgccaatta ttctgcctct tttgttgata ctgcaatgac
     5701 aggtcaatac aacactatgg acttggctgg tgtatctatg gcaaccagta tctggaatcc
     5761 tttctttaca tttctaacag ggattgtgtc agccttggtg cctatcattg gtcaccatct
     5821 tggtcgaggc aaaaaggaag aagttgcgtc tgatttttac caatttattt atttggcctt
     5881 gggcctatct gtggtcttgc tggggatggt acttttcttg gcaccaacaa tcttgaatca
     5941 tattgggtta gaagcagcag tagcggcagt agcggttcgc tatctttggt ttttatctat
     6001 cgggattatc cccttgttgc tctttagcgt cattcgttcc ttgctggatt cgctgggctt
     6061 gaccaaactg tccatgtacc tcatgctttt gttactccct ctcaatagcg gatttaacta
     6121 tctcttgatt tacggtgcct ttggtgttcc agaactggga ggggctggtg ctggtttagg
     6181 aacatccttg gcctactggg tcttgcttgg gatttctgtt ctggttttat ttaaacagga
     6241 gaagctcaaa gccttacacc ttgagaaacg aattccactt aatatggata aaattaagga
     6301 aggagttcgt ttaggtctgc ctattggggg aactgtcttc gcggaagtgg ctatcttttc
     6361 agtggttggc ttgattatgg ctaagttttc gtccttgatt atagctagtc accagtcagc
     6421 tatgaacttt tcaagtctta tgtacgcctt tcctatgagt atctcatcgg ctatggctat
     6481 tgtcgtttcc tatgaagtgg gagccaagcg atttgatgat gcgaaaacct atattggtct
     6541 aggaagatgg actgccctca tttttgcggc cttcacctta accttccttt acatttttag
     6601 gggaaatgtg gccagtcttt atggtaacga cccaaaattt atcgatttga cagcgcgttt
     6661 tttaacttat agtcttttct tccagttagc agataccttt gcggcgccgc ttcagggaat
     6721 tttgcggggg tataaggata cagttattcc tttttacctt ggtttgcttg gttattgggg
     6781 cgtagcaatc cctgtggcta cgctatttga ttccctaaca gattttggag cttattctta
     6841 ctggatcggc ttgattatta gtttgattgt gagtggggcg ctctaccgtt ggcgtttaac
     6901 tgtgattatg aagagatttg aatctttagc aaaatccaaa cgctaaaaag tttgtgaaaa
     6961 aatattcttg ataagaaaat cccttgtttt cacggggttt tcttttttat tttgtgaaat
     7021 ttcttttaga aaaactttga cagtatttgc caaaaacggt aaaatagtaa ggtaagaaga
     7081 aagttagaaa ggcaagaaga tgtcaacttt agataaaaat cttttgctag aaatgttccg
     7141 taagatggaa gaaatccgtc gcatggactt aaaaattgca caattagtaa agaaagggaa
     7201 agtgccagga atgacgcact tttctgttgg tgaagaggca gctaacgtgg gggctatgtt
     7261 agctctcaat ccagatgatc tgattacctc aaaccaccgt ggacacgggc aagctattgc
     7321 taaagggatc gacctcaacg gaatgatggc tgaaatcctt ggtaaataca ctggaacctg
     7381 taaagggaaa ggtggatcta tgcatatcgc tgaccttgat gctgggaacc ttggtgccaa
     7441 tggtatcgta ggtggtggta tggggatcgc tgtcggtgca gccctcagtc agcaaatgca
     7501 aaataccggt aaaatcgttg tctgcttctt tggagatggt gcgaccaatg aaggtgtttt
     7561 ccacgaagca gtgaacatgg cttctatctg gaacctgcca gtcattttct attgcattaa
     7621 caacggttac ggtatctctg cggatatcaa gaaaatgacc aatatagaac atatccatca
     7681 acgtagcgcc gcttatggaa ttcctggaat gttcatcgaa gacggtaaca atgtcatcga
     7741 tgtctatgaa ggatttcaga aagctgtaga ccatgttcgc agtggcaatg gtccagtctt
     7801 gattgaaagt gtaacttatc gctggctcgg tcactcatca tctgaccctg gtaaatatcg
     7861 tacgcgtgaa gaagtggaat tgtggaaaca aaaagatcca atcgaaaacc tccgcaatta
     7921 ccttattgaa aataacattg caagtgccga agaattggaa gaaatccaag cgcaagtaaa
     7981 ggaagcagta gaagcttctg ttaaatttgc agaggaaagc ccattcccac cgcttgaatc
     8041 agcctttgaa gatatttacg cagactaagg agaaagagat aaaatggaaa caaaaacaat
     8101 gtccttccgt gacaccatta tccttgctat gtctgaggaa atgcgtcgcg atgaaaatgt
     8161 gttcttgatg ggagaagacg tcggtgtctt cggaggagac ttcggtactt ctgttggaat
     8221 gcttgaagaa tttggtccag aacgcgtccg tgactgtccg atttctgaag ctgccatctc
     8281 tggagcagca gcaggagcag ccatgacagg acttcgtcca atcgtcgata tgaccttcat
     8341 ggacttctct gttattgcca tggacaatat cgtcaaccaa gctgctaaaa cacgttacat
     8401 gtttggtggt aaaggtcagg ttccaatgac tgttcgttgt gcagctggta acggagttgg
     8461 ctctgccgcc cagcactcac aatctctaga gtcttggttt actcacattc caggacttaa
     8521 ggttgtggca cctggaacac ctgcggacat gaaaggcctg cttaagtctt ctatccgtga
     8581 taaaaaccca gttattatac ttgagtacaa gtcagaattt aaccaaaaag gggaagtgcc
     8641 agttgatcca gactacacaa ttccacttgg ggttggtgaa atcaaacgcc aaggaacgga
     8701 tgtaacagtt gttacttatg gaaaaatgct tcgccgtgtg gttcaagctg ctgaagaatt
     8761 agcagaagaa ggaatttcag ttgaaattgt tgacccacgt acccttgttc cgcttgataa
     8821 ggatatcatc ataaactcag tgaagaagac tggtaaggtt gttctggtca acgatgccca
     8881 caaaacaagt ggctatatca gtgaaatttc agctattatt tcagaatcag aagcatttga
     8941 ctatctagat gcaccaatcc gccgttgtgc aggagaagat gtgccgatgc cttatgcaca
     9001 aaacctagaa aatgcaatga ttccaacagt tgaaagtatc aaagatgcaa tccgaaaaac
     9061 ttataacaaa gaatagagtt acataagata agttatgtaa ataaaataaa gctgacgaga
     9121 aactttgtat cttttaggtg cagagctctt cgtcattaat atcttatatt cgagcacggg
     9181 ctaaaagctc ggaaaaaaga taaatctcct tggcttcatc gaagccatcg tcgatttcct
     9241 atttttcagt cgcttttgac gccctttgta tcataaatag aattggagag gtcatggctg
     9301 atgacaagct aagagcgact cctgcagcta gaaagttagc ggatgattta gggataaacc
     9361 tctacgacgt ttctggctca ggtgcaaacg gtcgtgtcca caaagaagac gtggaaactt
     9421 ataaagacac aaacgtggtt cgcatttcgc cacttgcaaa acgaattgcc ctcgaacata
     9481 acattgcttg gcaggaaatc caaggaaccg gtcatcgtgg taaaatcatg aagaaggatg
     9541 ttttggccct gcttcctgaa aatatcgaaa acgatagcat caaatctcct gctcagattg
     9601 aaaaagtgga agaagtccct gataacgtaa caccatatgg tgaaatcgag cgtattccaa
     9661 tgacaccaat gcgtaaggtt attgcccaac gcatggttga atcttacttg actgcgccaa
     9721 ccttcaccct caactatgaa gttgatatga ctgaaatgtt ggctcttcgt aagaaggttc
     9781 ttgagccaat catggaagca actgggaaga agactactgt aacagacctt ctttcgcttg
     9841 cagttgttaa gactcttatg aaacacccat acatcaacgc ttcattgaca gaagatggca
     9901 agactattat cactcacaac tatgtcaatc ttgccatggc agttgggatg gataatggat
     9961 tgatgacacc tgttgtttac aatgctgaga agatgagtct ttcagaacta gttgtagcct
    10021 ttaaggatgt tattggccgt accttggatg gtaaattggc tccaagtgag ttacaaaatt
    10081 caacattcac aatcagtaat ttgggaatgt ttggtgttca gtcctttggc ccgattatta
    10141 accaacccaa ctcagctatc cttggtgtca gttcgacaat cgagaagcca gttgtcgtca
    10201 atggtgaaat tgtgattcgc ccaatcatga gtttaggatt aaccattgac caccgtgtcg
    10261 tagatggtat ggctggtgct aagtttatga aggacttgaa agagttgatt gaaaccccaa
    10321 tctcaatgtt gatttaagag caagagtatt catttttaag atatagataa aggaaggaag
    10381 acatggcctt agaaataatt atgccaaaag ccggcgtgga tatgacagaa ggacaaatcg
    10441 tccaatggaa taaaaaagtc ggagaatttg taaaagaagg agaaatcctt ttggaaatca
    10501 tgactgataa agtcagcatg gaattggaag ccgaagaaga tgggtacttg attgccattc
    10561 tcaaaggaga tggtgaaact gtccctgtaa cggaaattat cggttacctt ggtgaagaaa
    10621 gggaaaacat cccaacagct ggagcagcat cgccagaagc tagccctgta cctgtagcaa
    10681 gtacctcaaa cgatgatggt aagagcgatg atgcttttga tatcgttgtg attggtggag
    10741 gtcctgctgg ttatgttgca gccattaaag ctgcccaact cggcggtaag gttgcccttg
    10801 ttgagaaatc tgaacttggt ggaacctgct taaaccgtgg atgtattcca accaagacct
    10861 accttcataa cgctgaaatt attgaaaata tcggtcatgc tgcaaatcgt ggtatcgtga
    10921 ttgaaaatcc taacttcact gttgatatgg aaaaactttt agaaactaaa tctaaagttg
    10981 ttaatactct tgttggtggt gttgcaggac ttcttcgtag ctacggagtt actgttcata
    11041 aaggaattgg tacaatcact aaagacaaga acgtcttggt aaatggttct gaattgcttg
    11101 aaaccaagaa aatcattctt gctggtggtt caaaagtcag caagatcaac gtccctggta
    11161 tgcaatctcc acttgtcatg actagtgatg acattcttga aatgaacgaa gtgccagaaa
    11221 gccttgttat catcggtggt ggagttgtcg gtatcgaact cggtcaggcc ttcatgacat
    11281 ttggttcaaa agtgactgtt atcgaaatga tggaccgtat agttccagct atggatgcgg
    11341 aagtttctaa gaaccttcgc ttgatccttg agcgtaaagg aatgaccatc ttgactggta
    11401 ctaaactgca agaaatcatt gaggaaaatg gtcaacttcg tatcaaggtt gaaggaaaag
    11461 acgatatcat cgcaagcaaa gctcttcttt caattggtcg tatgccagac cttgaaggta
    11521 ttggagaggt tgagtttgaa ttggatcgtg gttgtatcaa ggtcaacgaa tacatggaaa
    11581 cttcagttcc aggcatttat gcaccaggtg acatcaacgg tactaagatg ttggctcacg
    11641 cagctttccg catgggtgaa gtttccgctg aaaatgccct taaaggaaat catgcagttg
    11701 ccaaattgaa tttgactcct gcagccatct acactctccc tgaagtagca gcagtaggtt
    11761 tgacagaaga acaagcccgt gagaaatacg atgttgccat cggtaagttt aactttgctg
    11821 ctaacggtcg tgctattgca tctgacgcag ctcaaggttt cgtaaaagtt atcgctgata
    11881 agaaatacgg agaaatcatt ggtgtacaca ttattggtcc tgcagccgca gaattaataa
    11941 acgaagcatc aagcatcatc gaaatggaaa tcactgttga ggaaatgctg aagaccatcc
    12001 acggacaccc aacttactct gaagtgatgt atgaagcgtt tgcagatgtt ctaggaatgg
    12061 ccatccattc acctaagaaa aaataaaacg aagatagatt agactggaag gttatttcca
    12121 gtctctatca tataaagtaa agggatatca tgaaatacat tatcaatcat tcaaatgaca
    12181 ctgcttttaa tattgccttg gaagaatacg cctttaaaca ccttttggat gaggatcaaa
    12241 tcttcctact ttggattaac aagccatcta tcattgttgg tcgtcaccag aacactatcg
    12301 aagaaatcaa ccgtgattat gttcgcgaaa atggtattga ggtagttcgc cgtattagtg
    12361 gtggtggagc tgtttaccac gatttaaata acctcaacta cacgatcatc tccaaagaag
    12421 atgaaaataa ggcatttgac ttcaagagct tctcaactcc ggttatcaat accctggctc
    12481 aactcggggt taaagctgag ttcacaggtc gtaatgacct tgagattgat ggtaagaagt
    12541 tctgtggcaa tgcccaagcc tatatcaacg gccgtatcat gcaccacggt tgcttgctct
    12601 ttgacgttga tttgtcagtc ctcgcaaatg cccttaaggt ttcaaaagat aaatttgaat
    12661 caaaaggtgt gaaatccgtc cgtgcccgtg taaccaatat tatcaatgaa ttaccaaaaa
    12721 aaatcacagt cgaaaaattc cgtgatttac tcttggaata catgaaaaaa gagtacccag
    12781 agatgactga atacgtcttt tcagaagaag aattggccga aatcaatcac atcaaggata
    12841 ctaagtttgg aacttgggac tggaactatg gtaaatcacc tgaatttaac gtccgtcgtg
    12901 gaaccaaatt cactagtggt aaggttgaag tctttgctaa cgttactgaa tcaaaaatcc
    12961 aagacatcaa gatttatggt gacttctttg gtattgaaga cgttgctgca gtagaagatg
    13021 tccttcgtgg ggtgaaatac gaacgcgaag atgttcttaa ggcgctaaaa accattgata
    13081 tcacacgcta cttcgctggt attagccgtg aagaaatcgc tgaagcggta gttggataaa
    13141 tcaaaaaaag aagttggcca acttcttttt ttgatattta tttacataat ttaaaatacg
    13201 tgaaatcata aactatctag agcattcttt tgttcatcat taacaatatg ggtatagagg
    13261 tcagtgactt gtgtgctggc atgtcctagt tggtgactga ctaaaacttg tgatttagtc
    13321 gcatcataga gcctagttgc tagcgtatgg cgcagtttat ggggtgttac acgtacttta
    13381 aaatcctctg agtatttagc aaccattttc tcaacgctag aagcatcgat acgattagga
    13441 acacctctgt agagagttaa aaaaagggct gtatctgttt tttccgtttt atagcgttga
    13501 ttccgaatgg ccagataatt ctctaaataa ggtttagcaa aagcagcgac attgactgag
    13561 tcacgtttgc caccttttcg agtaacatca ataaccatca tttttagatt gagatctctt
    13621 agatctagat taacagcttc agataagcga acaccagatg ccaagagaag ggcaataatg
    13681 gctaaatctc gttctttatt tttgttgaat gatgagagag ctcgatttga aagctgttgt
    13741 gggtgctctt gatcgatata agttagaaaa ccttctgttt catcacctag aaagagtttt
    13801 tgcttgatat tttcagctct ggcagcaagg gtttctttct ttttcttggt tgaaactttt
    13861 ttcattacat tacgatagaa ataaggttcc ccctgatcgt tttcaacctc ctcggttaga
    13921 tacttgtaaa gactagaaag tgctgataag gttcgattga tagttgtctg tgaaacacct
    13981 tgttttgttg tattagcatt cagcaaggga cgttcacgta gataaaggat aaaggattcc
    14041 atgtctttct tagacatatt ttccaaaact gataaaggaa tatcggatat tttatcagcg
    14101 tttgaaatac cagactccaa aacccagctg aaaaatcggt catattcctt aaggtattcg
    14161 tacagggttg taaaactgta gggcacagcc agcttagatt ggtagtattc cagaacatac
    14221 cagggcatga gttgttttag tttgtcgatt cgttccagta aaatctcacg tttcatgtat
    14281 tttctccata agtaagtata ctagtagtat agcatagact tgtatatttt tcaagaaaat
    14341 tatagttttt cagaaagatg ttataggagt ttttcaaagt gataaaaaga cttagaccta
    14401 caaacaaaac agaataagga aaataataaa aatctcaccc actaaacttc tgttaatact
    14461 acataactga agagctatat aaggagctat gagatacaaa acacattgta taatagattg
    14521 aaactagaat agtacatctg gacttctaaa acattgctag aaattgattt gattgttctg
    14581 attgttttat cctatttcta tttcatttca ctatataatt gctattgttt tctttttcat
    14641 gattttaatc ttactgtaca gatttgatac agtaaactcc tttctagctt tatactttat
    14701 catttctaac ttaattatag tcttattttt aataaagttc aattatttat atgtaaaatt
    14761 cctcatcagt aaaaaataac cgatctcatt tctgagaatc ggttttctaa ataaatcaag
    14821 ctgagtattt acataacata aattatgtaa atactcatac tacaacaaca aatctttgac
    14881 ttttccaatt tcactttttg gaataaccag gtgaatcata tcacccagat acattctggt
    14941 tgagccgtta actgtttggc tcttgccatt atggacttga gttgtgatga ggacgttgtg
    15001 tggtaagttg agttcatgaa cttgtttccc agcaatttta tcagaaactg gtatttcgat
    15061 aagtgtaact tctccttcgc tagatacttc ttctggaagc attttttcca gcatggcttc
    15121 atagactggc gtacctttga gcaaatccat gataatataa gaaacaagag tgacaagacc
    15181 aagtggcatg aggttgcgaa tatctcctac catctcagtt acgaggatca tagcggttaa
    15241 gggagctttt gatatggctc caaaatagcc actcattcct agaatgacaa atatagggaa
    15301 ttgctcttga ctgacaagtc caagattgac acagataaca ccaactaagg aaccaagcaa
    15361 agaaccaaga gctaaaatgg ggaggaaaat tcctcctggc agtccacttc catagctaat
    15421 catactccaa ataaagcgga tcaaaaagta agctaataaa acttggaaac taaaattttg
    15481 ttcagttaaa gaaaggacaa gctgatttcc gccaccaatg atttgaggta agaagattcc
    15541 gactggtatg ataatgataa aagccaagat gggataataa gccctatcca aatggatttt
    15601 ttgaccaatc aagtcataaa ctcttccaac gtttaataca gctttctcat agagaaaacc
    15661 tgaaaatcca aggaaaattc ccatgacgag atatatccaa tactggtcta gggtcatggg
    15721 aggaatgtta tctggcatat ccaatactgg tgtcaaaccg aacatgagta gagacacaaa
    15781 gtttgctacg atgctggctg ctagagttga gacccagaaa aagcgcgaaa aatggtgata
    15841 gacttcttct acaacaaaga gaagtgctgc aataggagca ttaaaggctg cggctaaacc
    15901 tgctgcagct ccactggcaa tcaaggaacg ttcctctact ggactggatt tgagccactt
    15961 ggcaattcct ttaccaccaa ctgctccaag ttgaatgctg ggtccctctc gacccagcat
    16021 gagtccactg gcaatagcaa gaatacctag cacatatttt ttccaaagaa tgccccacca
    16081 gttgagggac atgaggcctt tcagttcggc ttcgacttga ggaattcctg agcctttaat
    16141 atctttttct gaccgtgtta gtttggcact gagccaacag atgagtatat aaaacaaaac
    16201 cagtacaaaa agattgcgca ctaagtaccc ttgatcttga taaactcctt gtatcaggtg
    16261 gaagcccttt tcaattaaga aacgaaagga tccgacgata attccaacga tgaggccgac
    16321 aatgattcct cgaccaactt gggatagtat agtgctggat gcaaaggcga attctttctt
    16381 agaacggact atttccgact gttcctccat ggtatttcct ttcaattaac tttctttttt
    16441 acctaaaacc agtgatttaa cgggttcaaa gctggttcgg tgaattgggg taactcctag
    16501 ttttgtgagg ccttccagat gtttagctgt gccatatcct gcattagtag cgaaatcata
    16561 gccagggaac tgctgatcgt attccttcat caattcatca cgtgttacct tggctactat
    16621 agatgctgct gcgatagaga gggagttggc atctcctttg ataatggagg tttgtgaaat
    16681 gggcaagtcc agtttcatgg catcaatcaa aaggtgctct ggttgagggc tgagctggga
    16741 gattgcttct tgcatggcta gtttggttgc ttcatagata ttgacttggt cgatgacctg
    16801 attatctatg ataccaattc caatcgacaa ggcttggtct tgaacgactt ggaaaatctc
    16861 cagatgtttc tttttaggaa ttttcttgct gtcgttgaga cctttaatct tacaattttt
    16921 aggtaaaata acggccgcag cgactacagg accagcaaga ggaccacgac caacctcatc
    16981 aatacctgca attaaggtca atccttgctt ataaagttct ttttcataag aaagcatgga
    17041 ttccaagcgc aaattttcat ctaattcagc ttgaatggct cttttatgct tgctgatttc
    17101 cttttgaact cctgagcgat tatccttttc aagatctaaa aaaatagggc tttctaactc
    17161 cttgactgtc acaaggagtt ctttgatttc tttaatcgtt gccatcgagg ccttccaatg
    17221 tatctaaggt atagttaccg agtttgccat cacggacttc cttcacgaag agactgtaaa
    17281 aacggtcata gtcatcacgg aaaccgaggg cgcgggtcat atccataata atcacaggcg
    17341 cttcttcttc aattttcatt tgtttgaagc gttcagccag cttttctgga taatgttctt
    17401 tgaaataatt gataccaaaa atggtaacct catccatagg aagcaactga tccttgatag
    17461 ctccagtcaa tgccaactta agtgcaacag tttcatcctc aaacttaggc cagagaatcc
    17521 ccggtgtatc caagatttcc agatctttat tggttttaag ccattgttga ccttttgtga
    17581 cccctggctt gtttccaaca acagcaatct ttttaccagc caaacggttc atcagagttg
    17641 atttaccagc gtttggaatc ccaataatca tggtacgcaa ggtttcaatc tgaatcccac
    17701 gttctttctg gcgagcaatc ttatcagcca tgagcttctt ggccgcatct gttacaactt
    17761 ttacagtcac ttgctctttg gagttgatag ctagcgtctg gattccttgt gattcaaaat
    17821 actgacgcca ttccttggtc attgctggat cagccaagtc ggccttgttt aaaatcaaga
    17881 gttttggttt atcaccaaca atcttggtta acataggatt ttgactagat agaggtaagc
    17941 gtgcatcaac taaaatcgtc acaaaatcaa caaattttaa attctcctgc acctgtcgac
    18001 gagctttaga catgtgacca ggaaaccatt gaatagtagc cattgagttt tttcctttca
    18061 tagcaaggat ttagatcccc tattttattt tactattgtt tgaacataga gagttttcaa
    18121 atgaatgatg tccaaacagt tcttgtttta tgacatagaa atctacttta tattatatca
    18181 tgccttcttt attttgtccg atgatagcct tttaccctat atagaaaaaa gccatcaaat
    18241 gatgactttt cagagggagc aaaaaactgt tcccgtcata ttatgaacca aaagaactaa
    18301 actaccaaca gctaataggc ctaaagctgt aagtgcagaa gttgatgaac ctgttgcagg
    18361 aagagtttcc tgctgataaa taagagcata acttacttca ttatcagtag gaattcctgc
    18421 ttgaatcttg gtttgttctt catcaccttt ttaaacttta tttcctaata gtaaacacta
    18481 ttttttattc tcaaaaattg aacttctaaa atcatttgtt tggtcaagat aggctttaaa
    18541 gattgctctc ttcaacttat gaacggcact gtcgatttct ggatcataat tactccaacg
    18601 tggaccttca gcatccttga gaacagcttg gtccatgagg gcttgcaatt catccacatt
    18661 attgatagtc tttgtgccat agcttggcca tggttttgtc ggatctttaa aggtcacctg
    18721 cttcaagttt ccaaactgat ccactcgttc ttggtacata gctgtcttaa attctgccca
    18781 agttttatac ttaccgtcaa ataccttttt caaaacaagc tcatcggtca ccaagccccg
    18841 ttctttacca taaagattga tagtttgccc ttgttgttta gcatcttctt cgtattggtt
    18901 tgagatataa ggtaccattc catccttaaa gcctttggca gccaaaagtt cgtacgcaat
    18961 cctacgtccc ataaggtccc ctggtgtgcc tttctcactg ctgagagctg aatagattgg
    19021 ggcaaagagt ttgatggtat agtagccatt tcgttcatag tcgccagact ggtactcacg
    19081 agctgataag atgttgtggt caatcaaact ttcaaaacta ttcaggtttc gggcctctgc
    19141 ttctgtcaat tctttgacta cgttagtggc ataaacctca tttccatctg ctggatcttt
    19201 cacatacttg ttctcaattt ttctgagagc cgccattttc tggtaaacac ttagtttatt
    19261 aacgattgac tgcccttcga gatattccat catgtagata aggtcaaaca tgttatggac
    19321 atagttctga agatctgctg cgttttggaa tctctctgtc ggatccaaga cttgaagacg
    19381 ggatccctct gtactatctg attttgagtg tttcaagata gaattaatgg taatggttgc
    19441 gtcacttggt tggtcagggg cttgcaataa gccttttgcg aagaactctg gtcccaagcc
    19501 atttcttcga ccatagccac caaggtaaat atcctgatcc gaatcatggg tcatttcatg
    19561 ggtataagta atggctccat ccttgtccag catgcggtaa gacatatagt agacgccgtc
    19621 ccctgtagcg taggctccat gctggttgtg tactacctta ttgccaactg gtccaaagaa
    19681 gttcttcata gctggattgg agctatcaaa cttagcctcc gctgtagctt ttcctgatgt
    19741 tgtgtcatcc ccaaacttat aggcatcata aaggagaatc gtacgataga gtttttcgcg
    19801 tgactgttca tctaaaatac gataccaata atcgtagtga tctcgctgac gtttggctgt
    19861 ttcacgcgca ttttcttcaa caaaatcatt gagagccttg cccgctttat ggtcactact
    19921 gcggtagcga tcataagctc caaatcctag actagacatg gtcgagatga caaatacgga
    19981 tctctctggc aaggtcagga gaggcaagac catattgcgg tatttccatg tggcactcgt
    20041 gatacgatca taaacaccga tagaatactt ggtgccagct aacccttgct tcgttttcac
    20101 ctcttcgata gtggattttt cttcgacaat gtaagcctta gtctctgatt taaaccagtc
    20161 attattgctt gtatttggta aaaagacttt tcggtaatgt tccagcgtgc taaacaaatc
    20221 tgtcgttcca tgttgactgg caagactgat accataagta tcgacattat tcttagctag
    20281 aagattgtta aagccagatt tacctaactc aatcagagta tctagtgggg aagtatttcc
    20341 tttaccaaag aagtctggat gatacataac taggtctttg acattcactt gaccatagtt
    20401 aaagttatac caacgttcta aataagttaa accgagtagc aaggcttcct tattattctt
    20461 gattttatct acaagatagc ctctggtgac tgagttatcg ctagctagac cggcatctgc
    20521 tgacaaaagt tttttcaagc tgtctcccag attttgtttt gttttggaga actggtcttc
    20581 taaatagagc tcggttaact taacttctgg agaaatacca agtgtctttc tgatagcatc
    20641 tgactggtaa tcaagcttct gcaactcagg caagacttcc ttaacaatag agtctcgatc
    20701 atataagaat tggttaggag tgtagagaag tcccgtatta cctagattat attctgctag
    20761 attggcaaaa tcagtctggt acttgagatc aaatttctca gatgaatggt cattatagtg
    20821 aagtaagagt ttgtttgcag tctgtttgtt ggaaacaata tctgtgatta cttggtcatc
    20881 cttcatcata actgcagata agagttcttt ttggtataag agactgttct ccttaaccag
    20941 gtttccgtat ttgacgatgg ttgacttatt ataaaaaggt aacaattttt caatgttctt
    21001 ataaaccaaa gcacggttag cttgataatg ggctatctta gaaaaatcac tgtctttctt
    21061 gccacttgtt gagaggggtt ccaccgttgg tagagtgaga ggatttattt ctgctttttt
    21121 gcttacaatt tgagaagcat ctagcattgt tcctctttct tcaaaggatt ccttgctgac
    21181 gacctcatcc ttctctaaag tgacattgaa aactctatta gccttactac taaatgtatt
    21241 agctaccttc attcctgtat agtggtatcc agtgatggca tttccgtttg ttacattgac
    21301 atcgctaaga acattggtca attcaccagc gtgtttttcc tcaccagaag ttcgatccca
    21361 caaatatcct gccacaccag cgactttacc aaagtgcttg acattattaa tatcaccttc
    21421 cgcataactg ttctgtatat gcgcatcttg gtctactaga cctgcaagac caccgacagt
    21481 ctgatctgac ctattggtgt ttgacgaaat ggttactgtc gctttggatt tagcaataga
    21541 cgcatttttt cctgttaaat gaccgaccag accgccaata ttgtaggcat cagtcgtttc
    21601 ataggtattg acaattcttc ccttgaaact gctctctgcg atgcttgatt ggtctgcctt
    21661 agccaacaaa ccaccgacac cacgttctcc agccagaaca ccatcaacat gaacttgttt
    21721 aatctttgtg ccattcgtag cttcatttgc tagtgaacca atatcatttt tccctgaaat
    21781 agcaacattt tttagactca gtttttctac tgtagcacca ctcaagtttt caaacagagg
    21841 ttttttcaaa ttatagatag cataattctt gccatctttt tcaccgatta aacgaccagt
    21901 aaaggtgtcc ttgatatagg atctttcatc aggaccaagc tccacttcgt tagcattcag
    21961 gctggccgct aaatgatagg ttccagaggg attttggttt atagctttga ccaggttgct
    22021 aaaggaagta aagtttgtat tttcctcttt agccttctta tcgaggtaga aggtgaaatt
    22081 gtcgacatat ttattttcta gttcttgctg gagtttctca gctttggctg tgattttata
    22141 aactgactgc ccatttcttt tctcttcagt tattgaagct actggtatat agacatcttt
    22201 aaatgctgaa gattttacct tgacaaagta agtatccgta ttctctggaa ttccatccaa
    22261 tgaaacatgt tgtctgtagg ttccattcgt ctgactatac aactcaatat cagaaacatt
    22321 tcttaattcg agttttttct ctggttctgt ttgtccattc tctgatgttg tattacctga
    22381 attttctggt tttgttgcag ttccgttttt ttctggttga tttgattctt caactggtgg
    22441 ttttgaatca ctaggtttat tggatacttc tccagtattt tcgttagcta ttttcccaga
    22501 gtttgtttgt gtttcttctg caggttgaac tggtttttct gtttcttgat ttgaggtacc
    22561 ttctactgtg ccttcatttg gatttactgg aacttcttct acagtttttt ctgaattttc
    22621 atttttagag tcattatgtt ctggtttatt tgattctcca actgaggttg tcgaatcact
    22681 aggattactg gacacttccc cagtattttc gctagatgta tctggtgata ctttctctga
    22741 attcgttgtt gattcttctg caggttgaac tggattttct gcttcttgaa ttgaggttcc
    22801 ttctgtagta ccttcatttg gatttactgg tgtttcttct gttggtttta ctggaacttc
    22861 ttcagttttt tctggacctt gttctttggt cttctcaacc ggagtttcag gttttacttg
    22921 ctcaatatta cccttatatt ctggcaatgg ggctacctgc tctggttcac ctttatcact
    22981 taccacagta tctggcgact ctggttgaac ctcagtctca cctttgtcgg tcacaactgc
    23041 ttcgggtaat gtcggttgaa cttctggttc gcctttatca cttactacag cttcgggcaa
    23101 ctcaggctga attgcgggtt caacaataga tccagactgt acgtccttat gttctacacc
    23161 agtctcaggt tgttccttta taacttgagt ttttttagta cctttttcga ctattcttgg
    23221 actaggcgca gtcgttgaag ttgaaacaat ttctcgcgaa acttcttcct tgtttacaga
    23281 gaatattctg acgatttcaa ctttcttacc taatttacct tcttgtttta ctcttacagt
    23341 tccttcagct aaatcaggat tttcttgaat ttcttcttga aaatctattt ttgtctctat
    23401 agtttcctca cgatataaga gttcaggttt gttcaattga cctgataaaa cttcatcctg
    23461 tggatttaat gtatttaccc cagtcttttc ttttggagaa atcttctcct ctttcttcgt
    23521 ttctagattc ttatgttcgg ctaattgttc ttgagaatct gaagattgtt tctcttcttt
    23581 tcttggattg attaattcag tagagaaagg tttttcaact acttgaactt ctgtcggctt
    23641 agttgaagaa acaggtgttt gttcctgaat agcttgtact gttgatggat ggtctacaaa
    23701 atttggtgta acattataat ccaccttttg ttgttttgta ggagtggctg ctgatttttc
    23761 ttgattactt acttcaaaat cagaagtcgt ttttccctct ttgatatatc caatataagt
    23821 gtaacctgaa atctctttag gaagaggtaa tttttctcca gaggtcaatt catagtccgt
    23881 attgtaattt agcaaaagat gattttctaa agcatggact gaaactaaga caccatttcc
    23941 cattcccgca accaatacta aatgtaatac cgttttattc ttaacctttt tcttggaaac
    24001 agcaaaaatt aaaattccca gagcagctaa gctagcacca gcaactaggg cttgcctctc
    24061 attcttgctt ccagtatttg gtaattccgc cagttgattt tgagaattta acttataaac
    24121 aagataataa gtttcatcat cattctccac gtatgtcgga atatcataga caagctgctt
    24181 cttttcttct gatgatagct ctgaatctgc cacatattta tagtgaactc ccgcagtttc
    24241 ttgagcatcc acagatgaac tagctaatac agacataaaa aataaacttg aaatcgttgc
    24301 agatacaagt cctactgata attttctaaa tgaaaaacgc tcttgttttt caccaaaata
    24361 cttttccatt attcctcctt gaaataaaat ttatatatgt tacaaagacc tttattatat
    24421 tagtgtatta tctattatct atagaaaagg cagtatacct taattatact cttaatttac
    24481 aaaaaagtct taaaattgag atgcgctttc atactttgtt ttatattatt tgggggtaca
    24541 ataacaccta ccatgaaatt tacacggtag gtgttactca tatcactaat cgttctaaaa
    24601 atggtttgag gcagttgagg agaattcctt ctatccagct tccttgtgct gatgagcgat
    24661 ggtcttcctg caggcttttt tttagaaaat ctcggacttg ttctggtgcg atttcaaatt
    24721 caaaggcttt cattttatag aaaaagtcga tgagatgatc tgacaggtat tcagttgaaa
    24781 agggtacttc accacttttt cgatattcta ataagagtct agaaaatcga gctttttctt
    24841 caggaagctc acgaaaatag gaattgagga tccaagtctg cttctgtttt ctttcaattg
    24901 gatcctgact ggcaattcgt tggtcttttt ccagctcttt ttggtattgt ttggccttga
    24961 tagctcgttc tgctctattt ttaccaaaaa gaattttttc ccacttgcgt tcttcttgag
    25021 tcagggtctc tgtaaagcca aagtaatctt gataagcacg ctctgcgggt cccatggcta
    25081 gaaccagatt gtctgcatat tgcttggcga ttttatccct cttcttgcgt tctttctctg
    25141 cctggatacg gagttcttgt tcgtagtcaa ttttctcctt gcctagcttg acaaggtaga
    25201 gttggtcatc cgatttccca agtaaaaagg gtttgataca cttttcaagg acttcttcca
    25261 tccgagcctt tttctttggt tccgccttgg tccaacttcc tccctgaaag acttctagga
    25321 aaagctggta gtctctctca ggcgcaaatt gattgccacg attgggtttg aaaacacctt
    25381 tttcccagag ccattttaga agtcgctcgt caaagtcact tttattgacc ttgatttttt
    25441 cctttttctg agcttttctg gttagatttt caacctttct gagcagtttt tcttcctctt
    25501 ccaattgctg gtcaaggggc aatcgatgaa aatgacgaac acagtcgcta ccaattggaa
    25561 agaggcgttg gcctgtgaca ccgttaaaga gttcataagc gtatttgatg gcatttcgac
    25621 agacacaatt gctacggcca ataccgttaa aaatcaagga aacttcattc cattccttgg
    25681 tagcttgttc ccaagtatcc gctttcgaag cctgtaaaac tgcatcgtgc agggattttc
    25741 taactggaag tgtcatgagg tctcctttct aatactcaat aaaaatcaaa gagcaaacta
    25801 gaaagctagc cgcagtcagc tcaaaacact gttttgaggt tgtagataga actgacgaag
    25861 tcagtaacca tatatacagc aaggcgaagc tgacgtggtt tgaagagatt ttcgaagagt
    25921 ataagttata cttttacaac ttgaacctcg tctttaccga gtaaaatcaa gtatttttca
    25981 atattttcaa tcgaataggc tcgtgataaa gcctcttcgt atagagctaa ctgaccacga
    26041 tagcggtcta cgagttgact tggttcatca tagcggtctg tcttgtagtc gaacagaaca
    26101 attttgtttt cgtaaagcag atagccatca aggataccac ggacaacaaa gtcttcctga
    26161 ctcttttggt ctcgtttgag catggagaaa ggttgctcgc gatagagatg gtcggtatta
    26221 gcaagaattt cctgaccgag tgctgtgtca aagaaagcaa gaattttatc aagattgatc
    26281 ttgtctctga cagcttggct agtttgaact tgtttgagtg tttctgttaa gctagcaagg
    26341 gttagttgct ggctgaggtc aattatctgc atgagttcgt gagtagcact accaatctca
    26401 gctccagtta ccttttcttt ggttgaaaaa tctggcaaat cgaagctgat tttcttgcct
    26461 actgactgac cttgaccagc aatctcgaca ccttccatat ccataactgg ttcgtagaat
    26521 ttcttgattt gacttggggt ttgaacacta ggaagttcaa tagctgcgcg gtgaagagta
    26581 ttataaactt ccacctcctt cagcatttcc agagcttctt tgatggtatc tgactgacga
    26641 ttgtctgctt gggagctatc ttggagagga ctcttggttt ccaactctcc gatagcttct
    26701 ctggtcaact gatcttcgtc aataaaacga taactaaagt tgagcttgtc cttagtaaac
    26761 actttactga tagcccaaag ccaatcttgg aaattccgtg cttgcagtct agtattgcta
    26821 tttagtttcc catttttggc tgctgggtat tccttggatt ccagcttttc acgagaaccc
    26881 ttgccgacaa gatagagctt tttctcagcc cgcgtcatag caacatacag caaacgcatc
    26941 tgctcagaat agcttgctag ctgtaattcc tcttcgttct gcctataggt cagactagga
    27001 atggagagtt tgatggtttt aggatagtgg tcttctactg cccctgtctc catcttggca
    27061 atatatttga caccaagacc attctgacga ctgagaatga cttctgacat agagtcttgc
    27121 ttgttgaaat cttgatccat attgaggata aagacgtaag gaaactccag ccctttactc
    27181 ttgtggatgg tcatgagctc tactgcatct tttggcggtg cgacggccac gcttgccaaa
    27241 tcgtgctggg cttctaagac ttggtcaatc atacgaataa aacgcgacaa acctttgaaa
    27301 ttgctctttt caaattgatc agcacgcagt gctagggcat agagattggc ctgcctagca
    27361 ggaccattcg gcaaagcccc aacatagtca taataaaaac ggtcgttgta aatcttccaa
    27421 atcaagtcat agagagagtg ggttttggca tacaagcgcc aagaagctag gatatccatg
    27481 aattgcttta gtttttcaac tagagctgtg tgaatcaagc ctttttgact acttgccatt
    27541 ttttgtgcat tgaccagttt ctcatagaga ttttcgtgga ctttatcctc tgctttctga
    27601 agggacaaac gtgctagctc atcctcatca aaaccaaaca ttggagactt cataagggca
    27661 accaaggcgt agtcttgcag gggattgtga atgacacgaa gagtgtctag catgacttgc
    27721 acttctaggg attggagata attgttttgc tctccgtcag ttttgacagg aatcccgtac
    27781 tcagacaggg cgaggagaat ctggtcatta cgactgcggc tggaggtcag aagggcaatt
    27841 tccttaaagg caacaccttt ttcttgatga agtttcagaa tctccttgat aactaagcgc
    27901 atttcgcctg ttagtttcgt ttctgtttga ctctcttctt cctcacctgt atcgtccttg
    27961 tcgtagagga gaaattctgc cttgttgtct ggattgggag tcagtttggt attggcaaaa
    28021 acaagctggt gcttgttatc atagttgatt tcaccgacct cttggtccat gagacgttca
    28081 aagacatcat tggttgctga cagcacttct gaactactac ggaaattttc cttgaggaga
    28141 atgagcttgc cttcttgggg attttgcgca tagcgttgga atttctcatt gaaaatctgc
    28201 gggtctgcct gacggaaacg atagatggat tgcttgatat ctcccaccat aaagcgattg
    28261 tggccattag acaacaattc cagcatccgt tcttgaatat ggttggtatc ctgatactca
    28321 tcgaccatga cttcatggaa gcgctcctga taagactcac gaacttgtgg gaaattctct
    28381 aaaatctcaa tggtgtaatg gctgatatca gcgaattcaa aggcattttc ctggcgtttg
    28441 cgctgacgat aagcctccac aaaatgactc ataaaggttt ggaaggtttt agctagtttc
    28501 catgtgtctt gatgataacg ttcttgatag tcgagaatgg ttatctggtc tgataattgt
    28561 cctagtttag caaactgggt ctttctctct tcgttgtagg catcagccag gggcttcaaa
    28621 tcagccttac gactggcatt agtcagagct cgaccgtttt tctccttaga gatggcgaca
    28681 acacgcgcaa gcactgcctg ataagcctga ctatcggact cctgatttag ggagcaaatt
    28741 tcatccagaa ttaactgaac attttctaaa taggcagcct ttgcaaactc cttggcatcg
    28801 ttatccagat ggtaacggaa aaagctttcc aaatcccaaa gggcttgttt gatttgctca
    28861 gtcagttttt ctttttcact ggtaaaatca gctttctcaa atcctttgag gaaagattca
    28921 ctcagccact tttgaggatt actggtggat tggaggaagt catagatttt atagacctgc
    28981 tggcgcagac cccgttcgtc cttgccacgc ccagcaaagt ttttcagcaa atgactaaag
    29041 gtctctttct gtttaccttg gtaatgcgct tcaaagacct catgaaagac ttcgttttcg
    29101 agaagaagtt gctcgctttg gttttgtaaa atacggaaat taggtgcaat atcaagcaga
    29161 taaccatgtt tgccaaggaa tttttgtgtg aaagagtcca tggttccgat ggcagcgttt
    29221 ggtaggtctg ccaactggcg tcccaagtgt tgtttgaggt cgacatcatc tgtttcttgg
    29281 attttcttgc tgattttttt ctctaaacgt tctttaagtt cagttgcagc cttgacggta
    29341 aaggttgaga taaagagttg agaaatttcg acaccacgcg ccaattggtc cagaatgcgc
    29401 tctgccatga caaaggtctt tccagaacca gccgatgctg agaccaggat attctgacca
    29461 gaagtgtaga tagcttcgat ttgctcggca gttttctttt gttccttgct cgaatttgct
    29521 tctgcttctt gcagtttttg aatctcctcc tcacttaaaa agggaataag cttcatcgat
    29581 tcaactcctc tcttattttt tcaagccaag cttgcttgag tttttctccg accagacgct
    29641 tgccatcagc taggtccaac ttttctagga aacgggcttg gcccagatgg taattggctt
    29701 caaagcctgt aatagcctga tgttgctgga cgtatggggc aatgcttctg ccattttcag
    29761 tataaggatt gatggcgaac cggcctgcta aaatcttctc agcagctttc ttgtaaagat
    29821 aggcattgta gtccagtagg agctgaaatt cctcatctgt cagttgattc gccttgtttt
    29881 tgttataaaa ttcgcctaaa taactgcttt ctttttccaa gaagagccct tggtatttca
    29941 tagatttgct ggcttctacc actgctcctg ccagactttt taccgccatc agagattgga
    30001 caggttcagc catttccaag tacatggcgc cgaaaaagtt ctgctcccct tctcttttta
    30061 gggcagcaag ataggttggt aactgagaat tgagcccatt aaagaaatga ggaaactgga
    30121 actgagtcag actggatttg tagtctacta ctcctatcgc tccattagct ttcaaacggt
    30181 caatccggtc caccttgcct cgtacaaaga cactgcgtcc attgtctaat tgaataaagg
    30241 cttggtcttt tccaccaaaa tttgcttctt ctttgattgt ttcgatggct ggattgtgtc
    30301 ggagaatatg tccagttgtc cgtgcaacat caagcaaaac ttccttggta aactgggctt
    30361 ccaaactttc ttgataaata gcttcaaatt cgcgttcttg actggtttct tgaatagctt
    30421 gttctagacg ttggtcaaag gaatcttcat taggcaactg caaggcgcgt tcaaagatac
    30481 gatgcaagaa attcccgtga ctacgggcat caggacgcaa acgtaattcc tcctgcaagc
    30541 ctaaaacgta gcgtaggaaa taactgtatt cattgcgata aaactctgtc aaacccgacg
    30601 tagacaggta aaactcctgt ttggcaggat agagagcttg caaggtgtcc ttggctaagg
    30661 tcttgctgct tggactgatt gggatggctg gattttccag accttgctga tctagttttt
    30721 tacctatgac acgcgacaga accttgacaa aagtcaaatc ttgctcagta tcgctcatct
    30781 caccctgctg gtgataggca accagactag acaaaagact gtgataggac cccatatcct
    30841 ccttagacag tcctttgtga ttcatcctct tctctctccg cctaaatcca aaatggatca
    30901 actcttgaag ataggcagat tccttacttt cactttcgtt aaaaaggctt ggagccgaca
    30961 agaacaactg cttacgagca gaattgacca aggaaagcat agtgtagcga tttttcttga
    31021 gattttcact gctggcaatc agtaattgaa cgccttcttc ggtcgtttgg tttaggtttt
    31081 gcctttcttc atctgtcaga agactggtgt tttgagaaat ttttggtaaa ttgtcctgag
    31141 ttagtccaat agcatagaca aagtcagcag tcaatggtgc aatcaaatcg taactctgca
    31201 ccagaacagt gtccactgtt gctggaatgg tacggtattg ggacaaactc attccagaat
    31261 ggagcaaggc taggaagtct tccagactaa cctgtgaacc agcaaaaaca gtcgcaaatt
    31321 gttctaaaac atggcagaaa gccttccaaa cttcggcttg tctttcctgt tctacagctt
    31381 ccaaagtggt tgtcaaatct tgtaactgct tggtcacagc tccttctttt agaaagacac
    31441 tccatttttg taggaggttt tcagcctttt gttttcggct ggcaaagagg gtttcaagag
    31501 gtgctaaaat tctcaggcgg aggacattca aacgctcaag attaaatttt ccatggtggg
    31561 atttggtgaa agtttgctga aaggctggca agccattgat accaagatag cggatatatt
    31621 gctcaaaagc atcaatatca gactgactga ggtcagtata caaatcagtt ctaagaagat
    31681 taatcaaatc ctcctgacga aaacggtaac gttttaaagc taaaatagac tcgacaaact
    31741 gagtcaaggg atgatgagcc atggcttcgc ttctaccaag ataaaaagga atctgatact
    31801 ggtcaaaaat ggttttgaga gataactggt aagaagctac atcccccaag agaatacgaa
    31861 aatgcttgta gctcaggtct gagttctcat gtaatttctg acgaatgcta cgggctacta
    31921 gctccaactc ctccttttgc gtcaaacaag accagatttg taaattttca cggtctttct
    31981 catcgacatc caaagcgagt tctgaaaagt cataagaaga ctccaacaaa cgagaggcct
    32041 tgtcaaaact atccatcttc tcatgagttt gagaacagtc ctgagcaggc gtttggtatt
    32101 tagaagccag atgatggaga aattttacgc tggcttggta gagattgccc tcgctaaaag
    32161 gactggtata ggctttctta ctagcataag ccccgataac aatctcaaca cctttgccgt
    32221 gaagtaagtc cacaacccgc tcttcctcag cagaaaaacg agtaaagccg tcaatgacca
    32281 aggtgatttg attaaaatca ctacttacct tgtcattctc aatagcctca atcaaatggg
    32341 acaactgact tccctgggct aactgacctt gattaagata ggctgttact ttctcaaaaa
    32401 tcaagagtaa atccgccctc ttatcctcat ctgttaaatt ctccaagtcc aaaaaactca
    32461 tctgagattt ggtcatctca tggtaaagct caattaactg ctggatcaat tgaggatcct
    32521 gcttaatagc gccataaaca cgcaagtcct tgggatcgag ttcggcaagg catttgtaaa
    32581 aggccaaccc aagaccgata tcatcaagag tagttttaac tggtaaatca ttcaagacca
    32641 gataacgagc catttgagca aagcgcgtga cggtaatcga aaaagaagcc tgctgggaca
    32701 agcattccag cacggcgcgt tccttttcaa aagaaagaga gttgggggca atgtagaaga
    32761 cccgcttgcc agctgcaact agctcttctg cctctcttgt tagaatttct gtcaaagaag
    32821 ttcgaatatc agtataaagt aatttcatct cagcctcgtt ggaatttttc atcaccctat
    32881 attataccat gattagcctc gtaaatctgt taaaatattt aggccatcct ttcttttctt
    32941 catcatctgc taaatcttaa atacttagct ttacttgtat tagatagaat aagtctggct
    33001 actgaaaatc acataataaa aaagcctcgg taacaaggct ttgagtttta tgattgtttc
    33061 ttaggtacgg aatacacttc aatgtgttgt cccagtatct taatgtcgac tggtagattg
    33121 tctgatttat cgccatcaac atcggactct aattcgatat cagaagaagt tttaatatta
    33181 cgtgccttta tatattcaat attcttgata gaatgattga actatagtaa attgaaacta
    33241 taatagtaca ccgtggatgc taaaatattt ctagaaatta atttgatttc cctaatcaag
    33301 ctgttcgtat cttatttcaa tcta
//
LOCUS       DAVBDR010000017        32573 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.017, whole genome shotgun sequence.
ACCESSION   DAVBDR010000017 DAVBDR010000000
VERSION     DAVBDR010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 32573)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32573)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32573
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.017"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            complement(299..988)
                     /gene="rplA"
                     /locus_tag="VQ540_000835"
     CDS             complement(299..988)
                     /gene="rplA"
                     /locus_tag="VQ540_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HET2544661.1"
                     /translation="MAKKSKQLRAALEKIDSTKAYSVEEAVALAKETNFAKFDATVEV
                     AYNLNIDVKKADQQIRGAMVLPNGTGKTSRVLVFARGAKAEEAKAAGADFVGEDDLVA
                     KINDGWLDFDVVIATPDMMGLVGRLGRVLGPRNLMPNPKTGTVTMDVAKAVEESKGGK
                     ITYRADRAGNVQAIIGKVSFEAEKLVENFKAFNETIQKAKPATAKGTYVTNLTITTTQ
                     GVGIKVDVNSL"
     gene            complement(1195..1620)
                     /gene="rplK"
                     /locus_tag="VQ540_000836"
     CDS             complement(1195..1620)
                     /gene="rplK"
                     /locus_tag="VQ540_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004226069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HET2544662.1"
                     /translation="MAKKVEKLVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGMIIPVVISVYEDKSFTFVTKTPPAAVLLKKAAGVEKGSGTPNKTKVATVTR
                     AQVQEIAETKMPDLNAANVESAVRMIEGTARSMGFTVID"
     gene            complement(1743..2459)
                     /locus_tag="VQ540_000837"
     CDS             complement(1743..2459)
                     /locus_tag="VQ540_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HET2544663.1"
                     /translation="MKKRYLVLTALLALSLAACSQEKAKNEDGAAKTEQTAKADGTVG
                     SKSQGAAQKKAEVVNKGDYYSIQGKYDEIIVANKHYPLSKDYNPGENPTAKAELVKLI
                     KAMQEAGFPISDHYSGFRSYETQTKLYQDYVNQDGKEAADRYSARPGYSEHQTGLAFD
                     VIGTNGDLVTEEKAAQWLLDHAADYGFVVRYLKGKEKETGYMAEEWHLRYVGKEAKEI
                     AASGLSLEEYFGFEGGDYVD"
     gene            complement(2462..2932)
                     /locus_tag="VQ540_000838"
     CDS             complement(2462..2932)
                     /locus_tag="VQ540_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HET2544664.1"
                     /translation="MCLICQRIELIKKGENPYFVKELETGYLVIGDHQYFAGYSLFLA
                     KEHVSELHHLEKKTRIRFLEEMSVVQEAVAKAFAAEKMNIELLGNGDAHLHWHLFPRR
                     RGDMNGYGLNGRGPVWWIPFEEMTAEICQSKPDEIKRLVERLSSEVDKLLEIKE"
     gene            complement(2934..3971)
                     /locus_tag="VQ540_000839"
     CDS             complement(2934..3971)
                     /locus_tag="VQ540_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HET2544665.1"
                     /translation="MNQTVEYIKELTAIASPTGFTREISNYLVKTLEGFGYQPVRTAK
                     GGVNVTIKGQNDEQHRYVTAHVDTLGAIVRAVKPDGRLKLDRIGGFPWNMIEGENCTV
                     HVASTGQKVLGTILIHQTSCHVYKDAGTAERTQDNMEVRLDVKVSNEKETRALGIEVG
                     DFISFDPRTVVTDTGFIKSRHLDDKVSAAMLLNLLRIYKKEKIELPVTTHFAFSVFEE
                     VGHGANSNIPAQVVEYLAVDMGAMGDDQQTNEYTVSICVKDASGPYHYDFRQHLVALA
                     KEQDIPFKLDIYPFYGSDASAAMSAGAEVKHALLGAGIESSHSYERTHIDSVVATERM
                     VDAYLKSALVD"
     gene            complement(4069..5394)
                     /gene="brnQ"
                     /locus_tag="VQ540_000840"
     CDS             complement(4069..5394)
                     /gene="brnQ"
                     /locus_tag="VQ540_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006152071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HET2544666.1"
                     /translation="MAKKGTLTGLLLFGIFFGAGNLIFPPSLGALSGEHFLPAIAGFV
                     FSGVGIAVLTLIIGTLNPKGYIYEISTKIAPWFATLYLSVLYLSIGPFFATPRTATTA
                     YEVGISPLLSDANKGLGLIVFTVLYFAAAYLISLNPSKILDRIGRILTPVFAILIVIL
                     VVLGAIKYGGTSPQAASAAYQASAFGTGFLEGYNTLDALASVAFSVIAVQTLKQLGFS
                     SKKEYISTIWVVGIVVALAFSALYIGLGFLGNHFPVPAEAMKGGTPGVYILSQATQEI
                     FGSTAQLFLAAMVTVTCFTTTVGLIVSTAEFFNERFPQISYKVYATAFTLIGFAIANL
                     GLDAIIKYSIPVLVILYPITIAIVMIVIVNKFVALSKPGMQLTIAVVTVIAIASVLGS
                     SFKVEFLANLVSVLPFAKASLPWLVPAIVGILLSLVLPNKQESDVFEME"
     gene            complement(5565..5657)
                     /locus_tag="VQ540_000841"
     CDS             complement(5565..5657)
                     /locus_tag="VQ540_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HET2544667.1"
                     /translation="MRSARACQFLLEQGYNVINVQGGMLAFEEL"
     gene            complement(5700..5852)
                     /locus_tag="VQ540_000842"
     CDS             complement(5700..5852)
                     /locus_tag="VQ540_000842"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HET2544668.1"
                     /translation="MKEIAFDAFYQLYQNDQLSLVDVREVDEFAALHLEGAHNLPLSQ
                     LADSYD"
     gene            complement(6012..6590)
                     /locus_tag="VQ540_000843"
     CDS             complement(6012..6590)
                     /locus_tag="VQ540_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase family protein"
                     /protein_id="HET2544669.1"
                     /translation="MSQIERIKQAIMADSQNASYTERGIEPLFAAPKTARINIIGQAP
                     GLKTQEAGLYWKDKSGDRLRDWLGVDEDTFYNSGYFAVLPMDFYFPGHGKSGDLPPCT
                     GFAEKWHPQLLQELPDIQLTLLIGQYAQAYYLQEKISGKVTERVKHYKDYLPAYFPLV
                     HPSPRNQIWMAKNPWFEAEVVPDLKKRIKTIL"
     gene            complement(6644..8044)
                     /gene="pepV"
                     /locus_tag="VQ540_000844"
     CDS             complement(6644..8044)
                     /gene="pepV"
                     /locus_tag="VQ540_000844"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HET2544670.1"
                     /translation="MIAIDFTAEVEKRKEDLLADLFSLLEINSERDDSKADAQHPFGP
                     GPVKALEKFLEIADRDGYPTKNVDNYAGHFEFGDGEEVLGIFAHMDVVPAGSGWDTDP
                     YTPTIKDGRLYARGASDDKGPTTACYYGLKIIKELGLPTSKKVRFIVGTDEESGWADM
                     DYYFEHVGLAKPDFGFSPDAEFPIINGEKGNITEYLHFAGENTGAARLHSFTGGLREN
                     MVPESATAVVSGDLTDLQAKLDAFVAEHKLRGELQEEAGQYKVTIIGKSAHGAMPASG
                     VNGATYLALFLSQFGFAGPAKDYLDIAGKILLNDHEGENLKIAHVDEKMGALSMNAGV
                     FRFDETSADNTIALNIRYPKGTSPEQIKSILENLPVASVSLSEHGHTPHYVPMEDPLV
                     QTLLNVYEKQTGLKGHEQVIGGGTFGRLLERGVAYGAMFPDSIDTMHQANEFIALDDL
                     FRAAAIYAEAIYELIK"
     gene            complement(8057..8662)
                     /locus_tag="VQ540_000845"
     CDS             complement(8057..8662)
                     /locus_tag="VQ540_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002924506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HET2544671.1"
                     /translation="MKFLELNKKRHATKHFTDKPVDLKDVRTAIEIATLAPSAHNSQP
                     WKFVVVREKNAELAKLAYGSNFEQVSSAPVTIALFTDTDLAKRARKIARVGGANNFSE
                     EQLQYFMKNLPAEFARYNEQQVSDYLALNAGLVAMNLVLALTDQGIGSNIILGFDKSK
                     VNEVLEIEDRFRPELLITVGYTDDKLEPSYRLPVDEIIEKR"
     gene            8833..9633
                     /locus_tag="VQ540_000846"
     CDS             8833..9633
                     /locus_tag="VQ540_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HET2544672.1"
                     /translation="MKKFSLLLAILPFLVACGNQATPKETSAQKTIVLATAGDVPPFD
                     YEDKGNLTGFDIEVLKAVDEKLSDYEIQFQRTAWESIFPGLDSGHYQAAANNLSYTKE
                     RAEKYLYSLPISNNPLVLVSNKKNPLTSLDQIAGKTTQEDTGTSNAQFINNWNQKHTD
                     NPATINFSGEDIGKRILDLANGEFDFLVFDKVSVQKIIKDRGLDLSVVDLPSADSPSN
                     YIIFSSDQKEFKEQFDKALKELYQDGTLEKLSNTYLGGSYLPDQSQLQ"
     gene            complement(9815..10648)
                     /locus_tag="VQ540_000847"
     CDS             complement(9815..10648)
                     /locus_tag="VQ540_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001015777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HET2544673.1"
                     /translation="MNHKIAILSDIHGNATALEAVIADAKTQGASEYWLMGDIFLPGS
                     GANDLVALLKELPITASVRGNWNDCVLEALDGQYGLEDPQEIQLMRMTQFLMERMDPA
                     TTVWLRSLPLLEKKEIAGLRFSISHNLPNKNYGGDLLVENDTEKFDQLLDAETDVAVY
                     GHVHKQLLRYGSQGQQIINPGSIGMPYFNWEALKNHRAQYAVIEVEDGELVNIQFRKV
                     AYDYEAELELAKSKGLPFIEMYEELRRDDNYQGHNLELLASLIEKHGYVEDVKNFFDF
                     L"
     gene            complement(10638..12485)
                     /gene="uvrC"
                     /locus_tag="VQ540_000848"
     CDS             complement(10638..12485)
                     /gene="uvrC"
                     /locus_tag="VQ540_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HET2544674.1"
                     /translation="MNNLIKSKLELLPTSPGCYIHKDKNGTIIYVGKAKNLRNRVRSY
                     FRGIHDTKTEALVSEIVDFEFIVTESNIEALLLEINLIKENKPKYNIMLKDDKSYPFI
                     KITNERYPRLIITRQVKKDGGLYFGPYPDVGAANEIKRLLDRIFPFRKCTNPPSKVCF
                     YYHIGQCMAHTICKKDEAYFKSMAQEVSDFLKGQDDKIIDDLKSKMAVAAQSMEFERA
                     AEYRDLIQAIGTLRTKQRVMAKDLQNRDVFGYYVDKGWMCVQVFFVRQGKLIERDVNL
                     FPYFNDPDEDFLTYVGQFYQEKSHLVPNEVLIPQDIDEEAVKALVDTKILKPQRGEKK
                     QLVNLAIKNARVSLEQKFNLLEKSVEKTQGAIENLGRLLQIPTPVRIESFDNSNIMGT
                     SPVSAMVVFVNGRPSKKDYRKYKIKTVVGPDDYASMREVIRRRYGRVQREALTPPDLI
                     VIDGGQGQVNIAKQVIQEELGLDIPIAGLQKNDKHQTHELLFGDPLEVVDLSRNSQEF
                     FLLQRIQDEVHRFAITFHRQLRSKNSFSSQLDGIDGLGPKRKQNLMRHFKSLTKIKEA
                     SVDEIVEVGVPRAVAEAVQRKLNPQETEILLQVAEERVDYQTEGNHNKP"
     gene            complement(12525..13226)
                     /locus_tag="VQ540_000849"
     CDS             complement(12525..13226)
                     /locus_tag="VQ540_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="matrixin family metalloprotease"
                     /protein_id="HET2544675.1"
                     /translation="MRWLFRLIGAFFSFVWRLFWRLVWIVVLLCVLAFGLLWYLNGDF
                     QGALKQAERSVKMGQQSIDQWEKTGQLPKLSQTDSHQHSEGRWAQASARIYLDPQMDS
                     RFQEAYLEAIQNWNQTGAFNFELVTESSKADITATEMNDGGTPVAGEAESQTNLLTGQ
                     FLSVTVRLNHYYLSNPYYGYSYERLVHTAEHELGHAIGLDHTDEKSVMQPAGSFYGIQ
                     EEDVANLRKIYETSE"
     gene            complement(13305..14537)
                     /gene="murN"
                     /locus_tag="VQ540_000850"
     CDS             complement(13305..14537)
                     /gene="murN"
                     /locus_tag="VQ540_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurN"
                     /protein_id="HET2544676.1"
                     /translation="MALTTLTKEEFQTYSDQVSSRSFMQSVQMGDLLEKRGARIVYLA
                     LKQEGEIQVAALVYSLPMLGGLHMELNSGPIYTQQDALPVFYAELKEYAKQNGVLELL
                     VKPYETYQTFDSQGNPIDAEKKSIIQGLTDLGYQFDGLTTGYPGGEPDWLYYKDLTEL
                     TEKSLLKSFSKKGKPLVKKAETFGIRLKKLKREELSIFKNITKETSERREYSDKSLEY
                     YEHFYDTFGEQAEFLIASLNFSEYMSKLQGEQSKLEENLDKLRLDLSKNPHSEKKQNQ
                     LREYSSQFETFEVRKAEARDLIEKYGEEDIVLAGSLFVYMPQETTYLFSGSYTEFNKF
                     YAPALLQKYVMLESIKRGIPKYNFLGIQGIFDGSDGVLRFKQNFNGYIVRKAGTFRYH
                     PSPLKYKAIQLLKKIVGR"
     gene            complement(14542..15762)
                     /gene="murM"
                     /locus_tag="VQ540_000851"
     CDS             complement(14542..15762)
                     /gene="murM"
                     /locus_tag="VQ540_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurM"
                     /protein_id="HET2544677.1"
                     /translation="MYRYQIGIPTLEYDQFVKEHELANVLQSSAWEEVKSNWQHEKFG
                     VYREEKLLATASILIRTLPLGYKMFYIPRGPILDYGDKELLNFAIQSIKSYARSKRAV
                     FVTFDPSICLSQSLINQEKTEFPENLAIIDSLQQMGVRWSGKTEEMGDTIQPRIQAKI
                     YKENFEEDKLSKSTKQAIRTARNKGLEIQYGGLELLDSFSELMKKTEKRKEIHLRNEA
                     YYKKLLDNFKDKAYITLATLDVSKRSQELEEQLAKNRALEETFTESTRTSKVEAQKKE
                     KERLLEELTFLQEYIDVGQARVPLAATLSLEFGTTSVNIYAGMDDDFKRYNAPILTWY
                     ETARYAFERGMVWQNLGGVENSLNGGLYHFKEKFNPTIEEYLGEFTMPTHPLYPLLRL
                     ALDFRKTLRKKHRK"
     gene            complement(15874..16653)
                     /locus_tag="VQ540_000852"
     CDS             complement(15874..16653)
                     /locus_tag="VQ540_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HET2544678.1"
                     /translation="MAVMKIEYYSQVLDMEWGVNVLYPDANRVEEPECEDIPVLYLLH
                     GMSGNHNSWLKRTNVERLLRGTNLIVVMPNTSNGWYTDTQYGFDYYTALAEELPQVLK
                     RFFPNMTSKREKTFIAGLSMGGYGCFKLALATNRFSHAASFSGALSFQNFSPESQNLG
                     SPAYWRGVFGEIRDWTTSPYSLESLAKKSDKKTKLWAWCGEQDFLYEANNLAVKNLKK
                     LGFDVTYSHSAGTHEWYYWEKQLEVFLTTLPIDFKLEERLT"
     gene            complement(16722..18383)
                     /locus_tag="VQ540_000853"
     CDS             complement(16722..18383)
                     /locus_tag="VQ540_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HET2544679.1"
                     /translation="MSNISLTTLGGVRENGKNMYIAEIGESIFVLNVGLKYPENEQLG
                     VDVVIPNMDYLFENSDRIAGVFLTHGHADAIGALPYLLAEAKVPVFGSELTIELAKLF
                     VKGNDAVKKFNDFHVIDENTEIDFGGTVVSFFPTTYSVPESLGIVLKTSEGSIVYTGD
                     FKFDQTASESYATDFARLAEIGRDGVLALLSDSANADSNIQVASESEVRDEITQTIAD
                     WEGRIIVAAVSSNLSRIQQIFDAADKTGRRIVLTGFDIENIVRTAIRLKKLSLANEIL
                     LIKPKDMSRFEDHELIILETGRMGEPINGLRKMSIGRHRYVEIKDGDLVYIATAPSIA
                     KEAFVARVENMIYQAGGVVKLITQSLHVSGHGNVRDLQLMINLLQPKYLFPVQGEYRE
                     LDAHAKAAMAVGMLPEHIFIPKKGTTMAYENGDFVPAGSVSAGDILIDGNAIGDVGNV
                     VLRDRKILSEDGIFIVAITVNRREKKIVARARVHTRGFVYLKKSRDILRESSELINQT
                     VEDYLQGDDFDWADLKGKVRDNLTKYLFDQTKRRPAILPVVMEAK"
     gene            complement(18558..20780)
                     /gene="recJ"
                     /locus_tag="VQ540_000854"
     CDS             complement(18558..20780)
                     /gene="recJ"
                     /locus_tag="VQ540_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001832038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HET2544680.1"
                     /translation="MITPTYEWQFALQVEDADFTKIAKKAGLGPEVARLLFERGIQDQ
                     ESLKKFLEPSLEDLHDAYLLHDMDKAVERIRQAIEEGENILVYGDYDADGMTSASIVK
                     ESLEQLGAECRVYLPNRFTDGYGPNASVYKYFIEQEGISLIVTVDNGVAGHEAIALAQ
                     SMGVDVIVTDHHSMPETLPDAYAIVHPEHPDADYPFKYLAGCGVAFKLACALLEEVQV
                     ELLDLVAIGTIADMVSLTDENRILVQYGLEMLGHTQRIGLQEMLDMAGIAANEVTEET
                     VGFQIAPRLNALGRLDDPNPAIDLLTGFDDEEAHEIALMIHQKNEERKEIVQSIYEEA
                     KTMVDPEKKVQVLAKEGWNPGVLGIVAGRLLEELGQTVIVLNIEDGRAKGSARSVEAV
                     DIFEALDPHRDLFIAFGGHAGAAGMTLEVEQLSDLSQVLEDYVREKGADAGGKNKLNL
                     DEELDLEALSLETVKSFERLAPFGMDNQKPIFYIKNFQVESARTMGAGNAHLKLKISK
                     GEASFEVVAFGQGRWATEFSQTKNLELAVKLSVNQWNGQTALQLMMVDARVEGVQLFN
                     IRGKNAVLPEGVPVLDFPGELPNLAASEAVVVKNIPEDITQLKTIFQEQHFSAVYFKN
                     DIDKTYYLTGYGTRDQFAKLYKTIYQFPEFDIRYKLKDLAAYLNIQQILLVKMIQVFE
                     ELGFVTIKDGVMTVNKEAPKREIGESQIYQNLKQTVKDQEMMALGTVQEIYDFLMEKE
                     "
     gene            21057..21815
                     /locus_tag="VQ540_000855"
                     /pseudo
     CDS             21057..21815
                     /locus_tag="VQ540_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398007.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
     gene            21855..22619
                     /locus_tag="VQ540_000856"
     CDS             21855..22619
                     /locus_tag="VQ540_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000624332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HET2544681.1"
                     /translation="MISLFGLAAAKPVQADTSIADIQKRGELVVGVKQDVPNFGYKDP
                     KTGTYSGIETDLAKMVADELKVKIRYVPVTAQTRGPLLDNEQVDMDIATFTITDERKK
                     LYNFTSPYYTDASGFLVNKSAKIKKIEDLNGKTIGVAQGSITQRLITELGKKKGLKFK
                     FVELGSYPELITSLHAHRIDAFSVDRSILSGYTSKRTELLDDSFKPSDYGIVTKKSNT
                     ELNDYLDNLVTKWSKDGSLQKLYDRYKLKPSSHTAD"
     gene            22632..23309
                     /locus_tag="VQ540_000857"
     CDS             22632..23309
                     /locus_tag="VQ540_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET2544682.1"
                     /translation="MIDLSSWTAYFQDFGQFFNGFLFTLALAIGSFILAMVLGIFFGA
                     MSTSKRPILRILAHIFVEFYQNTPLLVQFVIVFYGLPLISDHTIMIPIYWTAVLCMGL
                     YHGAYIAEVIRSGIQSIPSGQMEAALSQGFTYISAMRLIILPQTFRIILPPLTNQIVN
                     LIKNTSTVAIISGVDLMFVTKSWSALNGNYIPAFLGAALLYFALCFPVAQFGRKMEQA
                     NKKAYSL"
     gene            23319..23978
                     /locus_tag="VQ540_000858"
     CDS             23319..23978
                     /locus_tag="VQ540_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET2544683.1"
                     /translation="MESILEVLTPDNLVFIFKGFGLTLYISLIAIILSTIIGTVLAVM
                     RNGKNPVLRIISSIYIEFVRNVPNLLWIFTIFLVFKMKSTPAGITAFTLFTSAALAEI
                     IRGGLNTVDKGQYEAGMSQGFTSAQILYYIILPQAIRKMLPAIISQFVTVIKDTSLLY
                     SVIALQELFGASQILMGRYFEPEQVFSLCILIALIYFSFNLAISSLSHMLAKRWQQAA
                     E"
     gene            24273..25463
                     /locus_tag="VQ540_000859"
     CDS             24273..25463
                     /locus_tag="VQ540_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferric reductase-like transmembrane
                     domain-containing protein"
                     /protein_id="HET2544684.1"
                     /translation="MKSVKGLLFIIASFILTLLTWMNTSPQFMIPGLALTSLSLTFIL
                     ATRLPLLESWFHGLEKVYTVHKFTAFLSIILLIFHNFSMGGLWGSRLAAQFGNLAIYI
                     FASIILVAYLGKYIQYEAWRWIHRLVYLAYILGLFHIYMIMGNRLLTFNLLSFLVGSY
                     ALLGLLAGFYIIFLYQKISFPYLGKITHLKRLNHDTREIQIHLSRPFNYQSGQFAFLK
                     IFQEGFESAPHPFSISGGHGQTLYFTVKNSGDHTNNIYDNLQAGSKVTLDRAYGHMII
                     EEGRENQVWIAGGIGITPFISYIREHPILDKQVHFYYSFRGDENAVYLDLLRNYAQKN
                     PNFELHLIDSTKDGYLNFEQKEVPEHATVYMCGPISMMKALAKQIKKQNPKTELIYEG
                     FKFK"
     gene            complement(25784..26665)
                     /locus_tag="VQ540_000860"
     CDS             complement(25784..26665)
                     /locus_tag="VQ540_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HET2544685.1"
                     /translation="MAIVSAEKFVQAARDNGYAVGGFNTNNLEWTQAILRAAEAKKAP
                     VLIQTSMGAAKYMGGYKVARNLIANLVESMGITVPVAIHLDHGHYEDALECIEVGYTS
                     IMFDGSHLPVEENLKLAKEVVEKAHAKGISVEAEVGTIGGEEDGIIGKGELAPIEDAK
                     AMVETGIDFLAAGIGNIHGPYPVNWEGLDLDHLQKLTEALPGFPIVLHGGSGIPDEQI
                     QAAIKLGVAKVNVNTECQIAFANATRKFARDYEANEAEYDKKKLFDPRKFLADGVKAI
                     QASVEERIDVFGSEGKA"
     gene            complement(26806..28134)
                     /gene="vncS"
                     /locus_tag="VQ540_000861"
     CDS             complement(26806..28134)
                     /gene="vncS"
                     /locus_tag="VQ540_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase VncS"
                     /protein_id="HET2544686.1"
                     /translation="MKRTGLFAKIFIYTFSIFSVLVICLHLAIYFLFPSTYLSHRQET
                     IGQKATAIAQSLEGKDRQSIEQVLDLYSQTSDIKGTVKGEMTEDKLEVKDSLPLDTDR
                     QTTSLFIEEREVKTQDGATMILQFLASMDLQKEAEQISLQFLPYTLLASFLISLLVAY
                     IYARTIVAPILEIKRVTRRMMDLDSQVRLRVDSKDEIGNLKEQINSLYQHLLTVIADL
                     HEKNEAILQLEKMKVEFLRGASHELKTPLASLKILIENMRENIGRYKDRDQYLGVALG
                     IVDELNHHVLQILSLSSVQELRDDRETIDLLQMTQNLVKDYALLAKERELQIDNSLTH
                     QQAYLNPSVMKLILSNLISNAIKHSVPGGLVRIGEREGELFIENSCSSEEQEKLAQSF
                     SDNASRKVKGSGMGLFVVKSLLEHEKLAYRFEMEENRLTFFIDFPKVVQD"
     gene            complement(28131..28787)
                     /gene="vncR"
                     /locus_tag="VQ540_000862"
     CDS             complement(28131..28787)
                     /gene="vncR"
                     /locus_tag="VQ540_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor VncR"
                     /protein_id="HET2544687.1"
                     /translation="MKILIVEDEEMIREGVSDYLTDCGYETIEAADGQEALEQFSSYE
                     VALVLLDIQMPKLNGLEVLAEIRKTSQVPVLMLTAFQDEEYKMSAFASLADGYLEKPF
                     SLSLLKVRVDAIFKRYYDTGRIFSYKDTKVDFESYSASIAGQEVPINAKELEILDYLV
                     KNEGRALTRSQIIDAVWKATDEVPFDRVIDVYIKELRKKLDLDCILTVRNVGYKLERK
                     "
     gene            complement(28836..28919)
                     /gene="pep27"
                     /locus_tag="VQ540_000863"
     CDS             complement(28836..28919)
                     /gene="pep27"
                     /locus_tag="VQ540_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_198524447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative autolysis signal peptide Pep27"
                     /protein_id="HET2544688.1"
                     /translation="MRKEFHNVLSSGQLLADKRPARDYNRK"
     gene            complement(29099..30478)
                     /gene="vex3"
                     /locus_tag="VQ540_000864"
     CDS             complement(29099..30478)
                     /gene="vex3"
                     /locus_tag="VQ540_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit Vex3"
                     /protein_id="HET2544689.1"
                     /translation="MLHNAFAYVTRKFFKSIVIFLIILLMASLSLVGLSIKGATAKAS
                     QETFKNITNSFSMQINRRVNQGTPRGAGNIKGEDIKKITENKAIESYVKRINAIGDLT
                     GYDLIETPETKKNLTADRAKRFGSSLMITGVNDSSKEDKFVSGSYKLVEGEHLTNDDK
                     DKILLHKDLAAKHGWKVGDKVKLDSNIYDADNEKGAKETVEVTIKGLFDGHNKSAVTY
                     SQELYENTAITDIHTAAKLYGYTEDTAIYGDATFFVTADKNLDDVMKELNGISGINWK
                     SYTLVKSSSNYPALEQSISGMYKMANLLFWGSLSFSVLLLALLLSLWINARRKEVGIL
                     LSIGLKQASILGQFITESILIAIPALVSAYFLANYTARAIGNTVLANVTSGVAKQASK
                     AAQASNLGGGAEVDGFSKTLSSLDISIQTSDFIIIFVLALVLVVLVMALASSNLLRKQ
                     PKELLLDGE"
     gene            complement(30530..31177)
                     /gene="vex2"
                     /locus_tag="VQ540_000865"
     CDS             complement(30530..31177)
                     /gene="vex2"
                     /locus_tag="VQ540_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding subunit Vex2"
                     /protein_id="HET2544690.1"
                     /translation="MTLLQLQDVTYRYKNTAEAVLYQIDYNFEPGKFYSIIGESGAGK
                     STLLSLLAGLDSPVEGSILFQGEDIRKKGYSYHRMHHISLVFQNYNLIDYLSPLENIR
                     LVNKKASKDTLLELGLDESQIKRNVLQLSGGQQQRVAIARSLVSEAPVILADEPTGNL
                     DPKTAGDIVELLKSLAQKTGKCVIVVTHSKEVAQASDITLELKDKKLTETRNTSK"
     gene            complement(31190..32467)
                     /locus_tag="VQ540_000866"
     CDS             complement(31190..32467)
                     /locus_tag="VQ540_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2544691.1"
                     /translation="MNPIQRSWAYVSRKRLRSFILFLILLVLLAGISACLTLMKSNKT
                     VESNLYKSLNTSFSIKKIENGQTFKLSDLASVSKIKGLENVSPELETVAKLKDKEAVT
                     GEQSVERDDLSAADNNLVSLTALEDSSKDVTFTSSAFNLKEGRHLQKGDSKKILIHEE
                     LAKKNGLSLHDKIGLDAGQSESGKGQTVEFEIIGIFSGKKQEKFTGLSSDFSENQVFT
                     DYESSQTLLGNSEAQVSAARFYVENPKEMDGLMKQVENLALENQGYQVEKENKAFEQI
                     KDSVATFQTFLTIFLYGMLIAGAGALILVLSLWLRERVYEVGILLALGKGKSSIFLQF
                     CLEVVLVSLGALLPAFVAGNGITSYLLQTLLASGDQASLQDTLAKASSLSTSILSFAE
                     SYVFLVLLSCLSVALCFLFLFRKSPKEILSSIS"
BASE COUNT         9193 a         7465 c         6056 g         9859 t
ORIGIN      
        1 tgatcgattc gtcctactct tatttcattt tactataatt gatagtggtc gccccagcca
       61 gataccttat ccgctatata ggccttatta tcatgttcct gttcgtagag ccacgatttc
      121 gctatccctt cctctgacga ttcttatttc ctgcgtcaga cttgggaatc gctattgggt
      181 tcaccggtag caggtgccca ccgaggactt acacctcaga tatacgacat gcccgtcgta
      241 catcaaaaaa agttgagaca tagcgtcttc aactttttta cattacttta actactgatt
      301 aaagtgagtt tacgtcaact ttgataccaa caccttgagt agttgtgata gtcaagtttg
      361 ttacgtaagt tcctttagct gtagctggtt ttgctttttg gattgtttcg ttgaaagctt
      421 taaagttttc aaccaatttt tcagcttcaa atgatacttt accgatgatt gcttgaacgt
      481 tacctgcacg gtcagcacgg taagtgattt taccaccttt agactcttca actgctttag
      541 caacatccat tgttacagta ccagttttag ggtttggcat caagttacgt ggtccaagga
      601 cacgtccaag acgtccaaca agacccatca tatcaggtgt agcgataact acgtcgaagt
      661 ccaaccaacc gtcgttgatt ttagcaacaa ggtcatcttc accaacaaag tctgcaccag
      721 cagcttttgc ttcttcagct tttgcaccac gtgcgaaaac aagaacgcgt gaagttttac
      781 cagtaccgtt tggcaatacc attgctccac ggatttgttg atcagctttt ttaacgtcga
      841 tgttcaagtt gtaagcaact tctacagttg cgtcaaattt tgcaaagttt gtttcttttg
      901 caagtgctac agcttcttct acgctgtatg cttttgtgct gtcgattttc tcaagagcag
      961 cacgaagttg tttgcttttt ttagccattt tctattctcc ttgtaagtgg ttcaatcgat
     1021 tttcatctcc cacgtcactt ctcgaaatga tgaagtcttg cgggttttca gtctattaga
     1081 ttcttttcct acggccttaa gctcccttgc tgtacccaag tacaagcatc agtcacttgc
     1141 ctagtatgaa aagcaactaa tagactgctg tgagattttc tactgtgtta ttgattagtc
     1201 aataacagtg aatcccatag aacgagcagt accttcgatc atacgcactg cagactctac
     1261 gtttgctgcg ttcaaatctg gcatcttagt ttctgcaatt tcttgtactt gtgcacgagt
     1321 aactgtagca actttagttt tattaggtgt acctgatcct ttttcaacac ctgcagcttt
     1381 tttcaaaaga acagcagctg gtggtgtttt cgtaacgaaa gtaaatgatt tatcttcgta
     1441 aactgagata acaactggaa tgatcatacc agcttggtca gctgtacgag cgttgaactc
     1501 ttttgtgaat cccatgatgt tgataccagc ttgaccaaga gcaggtccaa ccggtggagc
     1561 tggtgtagct ttaccagcag ggatttgcaa ttttacaagt ttttcgactt ttttagccat
     1621 ttttaaatcc tcctttgtgg ttttggcggt aattagagat ttttacctcc cacaagtatg
     1681 tttttcacat acccatctat tatacactat ttatctggaa ttgcaagaga aaagtttatt
     1741 ttttaatcga cgtaatctcc accttcaaag ccgaaatact cttccaaact gaggccacta
     1801 gctgcaatct ctttagcctc ttttccgaca taacgaaggt gccattcctc agccatatag
     1861 cctgtttcct tttccttacc tttgagataa cgtacaacaa agccataatc agccgcatga
     1921 tccaagagcc attgggccgc tttttcttct gtcaccaaat caccatttgt cccaatcaca
     1981 tcaaaggcta aacctgtctg gtgctcgcta tagccaggac gggcagaata acggtcggca
     2041 gcttctttcc catcttgatt gacataatct tgatagagct tggtctgagt ttcataactt
     2101 ctaaagccac tgtaatgatc gctaatgggg aaacctgcct cttgcatagc tttgatgagc
     2161 ttgaccaact cagccttggc tgttggattt tcccctggat tgtagtcttt tgacaatgga
     2221 tagtgtttgt tggctacgat gatttcatcg tatttccctt gaatgctgta atagtctcct
     2281 ttgttaacca cttctgcttt tttctgggca gctccttgag acttacttcc tactgttcca
     2341 tcagctttag cagtttgctc tgtcttagct gctccatctt cattttttgc tttttcttgt
     2401 gaacaagctg ctagactcaa ggctagcaag gctgtcaaga caaggtatct ttttttcatc
     2461 tttactcctt tatttctaat agtttatcta cttctgatga taaacgttcg actaatcttt
     2521 taatctcatc aggttttgat tggcagattt ctgctgtcat ttcttcaaag ggaatccacc
     2581 atactggacc acgtccattg aggccataac cattcatatc acctcttcgt ctaggaaaca
     2641 gatgccaatg gagatgagca tcgccatttc ctagtagttc gatattcatt ttctcagcag
     2701 caaaggcctt ggcaactgcc tcttggacca cactcatttc ttctagaaaa cgtattctag
     2761 ttttcttttc taaatgatgc aattcgctga catgttcctt ggctagaaag agactatagc
     2821 ctgcaaaata ctggtggtct ccaatcacaa gatagcctgt ttccaactct ttgacaaaat
     2881 agggattttc tcccttcttg atgagctcaa ttctctggca aatcaaacac atattagtct
     2941 accaatgcac tcttaagata ggcatcgacc attcgttctg ttgcgaccac cgagtcaata
     3001 tgagtgcgct cataagaatg actagactcg atacccgcac caagaagggc atgcttgacc
     3061 tctgcccctg cagacatagc cgctgaagca tccgaaccat aaaatggata gatgtccagc
     3121 ttaaaaggaa tatcttgctc tttagccaag gcaaccaagt gttgacggaa gtcatagtga
     3181 taaggacctg aggcatcctt gacacagata gatactgtgt actcatttgt ctgctggtca
     3241 tctcccatag ctcccatatc cacagccaga tattctacta cctgagcagg aatgttagaa
     3301 ttagcaccat gtcctacttc ttcaaaaact gaaaaagcaa aatgagttgt tactggcaat
     3361 tcaatcttct ctttcttata aatacgaagc aggttgagca acatcgctgc gctgacctta
     3421 tcatccaaat gacgagactt gataaaacct gtatcagtca caacagttcg tggatcgaag
     3481 ctgataaaat caccgacctc aatcccaaga gcacgagttt ctttttcatt gcttactttt
     3541 acatccaaac gcacttccat attgtcctgc gtgcgttctg cagttcctgc atccttgtag
     3601 acatggcaag aagtttggtg gatgaggatg gttcctaata ccttttgacc tgtgctagcc
     3661 acatgaacgg tacagttttc accttcaatc atgttccaag gaaaaccacc gatacggtcc
     3721 aatttaagac gaccatctgg tttgacagca cgaacaatag cacccagtgt gtccacatgg
     3781 gcagtcacat agcgatgttg ctcatcattt tgacctttga tggtcacatt gacaccaccc
     3841 ttggctgtgc gaactggctg gtaaccaaaa ccttctagag tcttgactaa ataattcgaa
     3901 atttcacgag tgaagcccgt tggcgatgcg atggctgtca gttctttgat atattctact
     3961 gtttgattca tttcttcacc tctttcgcta cctattataa cacatttatc atcggataaa
     4021 aaaagaaaat cactcctgta gacttggcta caaaagtgat ttaagtgatt attccatttc
     4081 aaaaacatcg ctttcttgct tgtttggtag aaccaatgag agcaagattc caacaatggc
     4141 tggcaccaac catgggagag atgccttggc aaaaggaaga acgctaacaa gatttgcaag
     4201 aaactcaacc ttaaacgagc ttcctagtac gcttgcaatg gcaataactg taaccacagc
     4261 aattgtcaac tgcatacctg gttttgaaag ggcaacaaat ttgttgacaa tgacaatcat
     4321 aacgatagca atcgtgattg ggtacaagat aaccagtact ggaattgagt acttgataat
     4381 cgcatcaaga cccaaattgg caatagcaaa tccaatcaag gtaaaggctg tcgcataaac
     4441 cttgtagctg atttgtggga agcgctcatt aaagaactca gctgttgaca caatcaaacc
     4501 aacagtcgtt gtgaagcagg ttacggtaac catagctgca aggaagagtt gagctgttga
     4561 gccaaagatt tcttgagtgg cttgtgacaa gatgtaaaca cctggtgttc cacccttcat
     4621 cgcttcagct ggtactggga aatgatttcc aagaaaacct aaaccgatgt aaagagcgct
     4681 gaaggcaagg gcaacaacga taccaacaac ccaaatagtt gaaatgtatt ctttcttact
     4741 tgaaaatcca agttgtttca aggtttgaac tgcgattacg ctaaaggcca ctgaggcaag
     4801 ggcgtccaag gtattataac cttctaggaa acctgtacca aaggcagaag cttgataagc
     4861 agctgaagca gcttgaggac ttgttccacc atatttgata gctcccagaa cgaccaagat
     4921 aacaatcaaa attgcaaaga ctggcgttaa aatacgtcca atgcggtcta agatttttga
     4981 tggattaagc gaaatcaaat aggctgccgc aaaatacaga accgtaaata caatcaagcc
     5041 aagtccttta tttgcatccg acaaaagggg gctaatccct acttcgtaag ctgttgtagc
     5101 agtacgtggg gtagcaaaga atggaccgat tgacaagtaa agaactgaga ggtaaagagt
     5161 cgcaaaccaa ggcgctatct tcgttgaaat ctcgtagata tatcctttag gatttagcgt
     5221 tccaataata agggtcaaga cggcgatacc aacgcctgaa aagacaaaac ctgcgatggc
     5281 aggaagaaaa tgttctccag atagagcacc tagagaaggc ggaaaaatca agttccccgc
     5341 accaaaaaat attccaaaca ggagcaaacc tgttagggta ccttttttag ccataaaaat
     5401 ctccttcata tttataaaat actgatctag tataccacga ttaggagtct gaaaaaagca
     5461 tcacgaggca aatattaaat gttttcaatt ttcttaaaaa taagaattat ctaaaaataa
     5521 aactctccta cccagtccac accaagtagg agaaatgcaa aattttaaag ttcttcaaag
     5581 gctaacatgc caccctggac attgataaca ttataacctt gttctaatag gaattggcaa
     5641 gcacgcgccg atctcattcc agatttgcaa ataatataat gcaagcgatc tttgtccaat
     5701 taatcataac tatcagccaa ttgactaagc ggtaggttgt gggcaccttc taaatgaaga
     5761 gctgcaaact catccacttc tctcacatcc actagagaaa gctggtcgtt ttggtaaagc
     5821 tggtaaaatg cgtcaaaggc tatttctttc attctttttc ttctaatact cttcgaaaat
     5881 ctcttcaaac cacgtcagcg tcgccttacc gtgcgtatgt taccgacttc gtcagtttta
     5941 tctgcaactt caaagctgta ctttgagcag cctacgacta gcttcctagt ttgctctttg
     6001 attttcattg actataaaat ggttttaatt ctttttttca aatctggcac tacttctgcc
     6061 tcaaaccaag gatttttggc catccagatt tgatttcgtg gtgatgggtg aactagcgga
     6121 aaataggctg gcagatagtc tttatagtgt ttcaccctct ccgttacctt cccactgatt
     6181 ttctcctgta aatagtaggc ttgggcatat tgcccaatca agagggttaa ctgaatatca
     6241 ggcaattcct gtaagagctg cggatgccat ttttctgcaa aacctgtaca aggcggaaga
     6301 tcacccgact tgccatgtcc tggaaagtag aaatccatag gcaaaacagc aaaataacct
     6361 gaattgtaaa aggtatcttc atccacacct agccagtccc gcaaacggtc accactttta
     6421 tctttccagt aaaggcctgc ttcttgagtt ttaagtcccg gagcctgacc gatgatattg
     6481 atgcgagcag tttttggcgc tgcaaagaga ggctcaatgc cacgctctgt atagctggca
     6541 ttctgcgaat ccgccatgat agcctgtttg attctttcga tttgagacat ctactttccc
     6601 tccaaaaaga agtccaagca taagatctca gacttctatc gttttatttg atcaattcgt
     6661 aaatagcttc ggcataaatt gctgctgctc ggaagagatc gtccaaggca ataaattcat
     6721 tggcttggtg catggtatca attgagtctg ggaacatagc accataggca actccgcgct
     6781 ctaacaagcg accaaaggtt ccaccaccga tgacttgttc atgaccttta aggcctgttt
     6841 gtttttcata gacattcaac aaggtttgca caagtggatc ttccattggc acatagtgag
     6901 gggtatgacc atgttctgat agactgacag aagcaactgg caagttttct aggattgact
     6961 tgatttgttc tggacttgtt ccttttggat agcggatgtt aagggcaatg gtattatcag
     7021 cacttgtttc atcgaagcgg aagacgccgg cattcataga aagagcaccc atcttttcat
     7081 ccacatgagc aatcttgaga ttttcaccct catgatcgtt caagagaatt ttacctgcga
     7141 tgtcaaggta gtctttggct ggaccagcaa agccaaactg gctgaggaag agggcaaggt
     7201 aagttgcgcc attgacacct gaagcaggca tagcaccgtg ggctgattta ccaatgatcg
     7261 tcaccttgta ttggccagct tcttcttgga gttctcctct aagtttgtgt tctgcaacaa
     7321 aggcatctag tttagcttgc aagtctgtca agtcacctga aacgactgct gttgctgatt
     7381 ctggtaccat attttcacgt aaaccacctg taaagctgtg aagacgggct gcacctgtat
     7441 tttcacctgc aaagtggagg tattccgtga tgtttccttt ttcaccattg atgattggaa
     7501 attcagcatc tggtgagaaa ccaaagtctg gcttggcgag tcctacgtgc tcgaagtagt
     7561 agtccatatc tgcccagcct gattcttcgt ctgttccaac gatgaagcga actttcttag
     7621 aagttggaag gcccaattct ttgatgattt tcaaaccata gtagcaagct gttgtaggtc
     7681 ccttgtcatc tgaagcacca cgcgcataaa ggcgaccatc tttgatagtt ggtgtgtaag
     7741 ggtctgtgtc ccaaccgcta ccagctggaa ccacgtccat atgggcaaag attccgagaa
     7801 cttcttctcc atcaccaaac tcaaaatgtc ctgcatagtt atcaacattt ttagttggat
     7861 aaccatcacg gtctgcgatt tcaaggaatt tttccaaggc ttttactgga ccaggtccaa
     7921 atggatgttg ggcatcagcc ttgctatcat cacgttctga gttgatttcc aaaaggctaa
     7981 acaagtcagc caagaggtct tctttgcgtt tttctacttc tgctgtaaaa tcaattgcta
     8041 tcattttttc ttcttcctat cttttttcga tgatttcatc tactggcaag cggtagcttg
     8101 gttccaattt gtcgtctgtg taacccactg tgatcaagag ttctgggcgg aaacggtctt
     8161 caatttccaa aacctcattg acttttgatt tgtcaaaacc aaggataata ttggaaccaa
     8221 ttccttggtc tgtaagagcg agaaccaagt tcatagcaac caaacctgca ttgagtgcta
     8281 ggtagtcgct gacttgttgt tcattgtagc gtgcaaattc agctggcaaa tttttcatga
     8341 agtattgaag ttgttcttct gagaaattgt tagcaccacc aactcgggca atcttacgag
     8401 cgcgtttggc aaggtctgta tctgtaaata gggcaatggt tacaggtgct gatgatacct
     8461 gctcaaagtt tgaaccataa gccaactttg ccagttcagc atttttctca cgaacaacta
     8521 caaatttcca aggctggctg ttgtgggcgc ttggcgccaa ggttgcaatt tcgatagccg
     8581 tacgcacatc ttttagatca acaggcttat cagtgaaatg cttggtcgca tgacgttttt
     8641 tatttaattc aagaaatttc ataatcgatt tccttttcta attctactgc ttccattcta
     8701 ccataatttg aaagagcttg cagggatttt tcatgattaa gtttttctat cacagacata
     8761 aaagatatat attggtttat caggaaagtt tctgataaac tagcaagtac tttacatttg
     8821 aatggagaca gtatgaaaaa atttagccta ttactagcta tcctaccatt tttggttgcc
     8881 tgtgggaatc aagctacacc caaagagact agcgctcaaa agacaatcgt ccttgctaca
     8941 gctggcgacg tgccaccatt tgactacgaa gataaaggca atctgacagg cttcgatatc
     9001 gaagttctaa aggcagtaga tgaaaaactc agcgactacg agattcaatt tcaaagaacc
     9061 gcctgggaaa gtatcttccc aggacttgat tctggtcact atcaggctgc ggccaataat
     9121 ttgagttaca caaaagagcg tgctgaaaaa tacctttact cgcttccgat ttccaacaat
     9181 cccctcgtcc ttgtcagcaa caagaaaaat cctttgactt ctcttgacca gatcgctggt
     9241 aaaacaacac aagaggatac cggaacttct aacgctcaat tcatcaataa ctggaatcag
     9301 aaacacactg ataatcccgc tacaattaat ttttctggtg aggatattgg taaacgaatc
     9361 ctagaccttg ctaacggaga gtttgatttc ctagtttttg acaaggtatc cgttcaaaag
     9421 attatcaagg accgtggttt agacctctca gtcgttgatt taccttctgc agatagcccc
     9481 agcaattata tcattttctc aagcgaccaa aaagagttta aagagcaatt tgataaagca
     9541 ctcaaagaac tctatcaaga cggaaccctt gaaaaactca gcaataccta tctaggtggt
     9601 tcttacctcc cagatcaatc tcagttacaa taacactctt cgaaaatctc ttcaaaccac
     9661 gtcagcttta tctgcaacct caaagctgtg ctttgagcaa cctacggcta gcttcctagt
     9721 ttgctctttg attttcattg agtataagat atactaaaag cgattggacc agccaatcgc
     9781 ttttttagtt tgcattggct attttaggaa actcttacaa aaaatcaaaa aaattcttca
     9841 catcctctac atacccatgc ttttctatta agctggctaa aagttccaga ttgtgcccct
     9901 gatagttatc gtcacgacgc agttcttcat acatttcaat aaagggaagc cccttggact
     9961 tggccaattc taactcagcc tcgtaatcat aagcaacttt acgaaattgg atattgacca
    10021 attccccatc ttcaacttct atcacggcat actgggcacg gtgatttttt aacgcctccc
    10081 aattaaaata gggcatgcca atcgaccctg gattgatgat ttgttgccct tgacttccat
    10141 aacgaagcaa ctgcttgtga acatgaccat aaactgccac gtccgtttcc gcatctagca
    10201 gttggtcaaa tttctctgta tcattctcaa ctagcaagtc accaccatag ttcttatttg
    10261 gcaaattatg agagatagaa aagcgcagtc cagcaatttc tttcttttcc agcaaaggca
    10321 agcttcgtag ccagacagtc gttgcaggat ccattcgctc catcaaaaac tgagtcattc
    10381 gcatgagctg gatttcctgt gggtcttcta agccatattg cccatctaaa gcctcaagga
    10441 cacaatcatt ccaattgcct cgaacacttg ccgtgatagg aagttccttt aacagagcga
    10501 ccaagtcatt tgcacctgaa ccagggagga aaatgtctcc catgagccaa tattcactgg
    10561 ctccttgagt tttagcatct gcaatcactg cttctagcgc cgtcgcattg ccatgaatat
    10621 ctgataaaat tgcgatttta tggtttattg tggtttcctt ccgtttggta atctactctt
    10681 tcttccgcca cttgaagcaa gatttctgtt tcctgcgggt tcaactttct ttgcacagcc
    10741 tctgctactg ctcttggtac tccaacttcg acaatctcat ccacactggc ttccttgatt
    10801 ttggtcagag acttgaagtg cctcatgaga ttttgcttgc gtttaggtcc cagaccatca
    10861 atcccatcca attgagatga gaaagaattt ttggagcgca gttggcggtg gaaggtaatg
    10921 gcaaagcggt ggacctcatc ttgaatgcgt tggaggagga aaaattcctg agaattgcga
    10981 gacaagtcca ccacttccag cggatctcca aagagcaatt catgggtttg gtgcttatca
    11041 ttcttttgca gacctgcaat tggaatatcc aagcccagtt cttcttggat gacttgctta
    11101 gcaatattga cttgaccttg ccccccatca atcacaatca aatctggagg agtcaaagcc
    11161 tcacgctgta ctcgaccata gcgtcttcga atgacttctc tcatactagc atagtcgtcc
    11221 ggcccaacaa cggtttttat cttgtactta cggtaatctt ttttacttgg cctgccgtta
    11281 acaaagacca ccatggctga aacaggactg gtccccatga tgttggagtt atcgaaggac
    11341 tcgatgcgaa ctggagtcgg aatttggagc aaacgtccta gattttcaat agctccttgg
    11401 gtcttttcga ctgatttttc tagcaggtta aatttctgct ccagactaac acgtgcattt
    11461 tttatggcta gattgaccag ctgttttttc tctccacgtt ggggtttgag aatcttggta
    11521 tccaccaaag ccttgacagc ttcttcgtca atatcctgcg gaatcagtac ctcattggga
    11581 actaggtgag atttttcttg atagaattgt cccacatagg tcaagaaatc ctcatctgga
    11641 tcattgaagt aggggaagag attgacatcg cgctcgatga gcttgccctg acgaacaaag
    11701 aaaacctgca cacacatcca gcccttatcc acatagtagc caaagacatc gcgattttgg
    11761 agatccttag ccatgacccg ttgcttggtt cgaagcgttc caatagcctg aatcaggtca
    11821 cggtattccg ccgcacgttc aaactccata ctttgtgctg ctactgccat tttactcttg
    11881 agatcatcga tgattttgtc atcctgacct ttcagaaaat cagacacctc ctgagccata
    11941 gacttgaaat aagcctcatc cttcttacag atggtgtggg ccatacactg gccgatatgg
    12001 taataaaaac agaccttaga gggcgggttg gtacattttc gaaaagggaa aatcctatct
    12061 agaagtcgct tgatttcatt ggctgccccc acatctggat aagggccaaa ataaagacca
    12121 ccgtcctttt tgacctgacg agtaatgata agccgtggat agcgctcatt ggtgattttg
    12181 atgaaaggat aggacttgtc atccttgagc atgatattgt acttgggctt attttccttg
    12241 atcaagttga tttccagcag aagcgcctca atattggact cagtgacgat aaattcaaaa
    12301 tccacaattt cagacaccag agcctctgtc ttggtatcat gaattccacg aaaataggac
    12361 cgtactcgat tacgcagatt tttagccttt cctacataga taatggtgcc atttttatcc
    12421 ttatgaatgt agcaaccagg gctggtcggc aagagctcta gttttgattt aatcaagttg
    12481 ttcatagttc cattatagca aaaaaagtag ggaaagatag taccctactc actagtctca
    12541 tatatttttc ggaggtttgc aacatcctct tcctggatac cataaaagga acctgctggt
    12601 tgcatgacag acttctcatc tgtatggtcc aagccaatcg catgacctaa ctcatgttct
    12661 gccgtatgga caaggcgttc ataggagtag ccatagtatg gattggacaa ataataatga
    12721 ttcaaccgca ccgttacgga caagaattgc cctgttaaga gattagtttg actttccgcc
    12781 tctcctgcca caggagtgcc tccgtcgttc atctccgtag ccgtaatatc cgccttacta
    12841 gactcagtca cgagttcaaa gttaaaagca ccagtttgat tccagttctg gattgcttct
    12901 aaataagcct cttgaaagcg tgaatccatc tgcggatcca ggtaaatacg agcagaggcc
    12961 tgtgcccacc ttccttcaga atgctggtga ctatctgtct ggcttaactt aggcagttgc
    13021 cctgttttct cccattggtc aatactttgt tgacccattt ttactgaccg ttctgcttgc
    13081 tttagcgctc cttgaaaatc cccgttcaga taccagagaa gtccgaaagc aagcacacat
    13141 aagagcacaa ctatccaaac cagacgccaa aacaaacgcc acacaaaaga aaagaaagcc
    13201 cctatcaaac gaaaaagcca gcgcatgtct ctccaccttt ctagcaaata agaattattt
    13261 tactaaaaga agctaaaaga aatctaaata ctgacttttt catcttaacg tcctactatt
    13321 tttttgagta actggatagc tttgtatttt aaaggcgatg gatggtaacg gaaagtacct
    13381 gctttgcgta caatatagcc attaaaattc tgtttaaaac gcaaaacacc atcacttcca
    13441 tcaaaaatcc cttgaatgcc taggaagttg tatttaggta ttccacgttt tatgctttcc
    13501 aacataacat atttttgaag cagtgcaggg gcatagaact tattaaactc agtgtaggaa
    13561 ccactaaaga gataagtcgt ttcctgaggc atataaacaa ataaactccc agctaaaaca
    13621 atatcttctt ctccatattt ttcaatcaag tctcgcgctt ctgcttttcg aacttcaaac
    13681 gtttcaaatt gactagaata ttctctcagt tgattttgtt ttttctcaga atgaggattt
    13741 ttactcaaat caagtcgcaa cttgtccaag ttttcttcta gtttactttg ttcaccttgc
    13801 aatttgctca tatactccga aaaattcaag cttgctatga gaaactccgc ttgttctcca
    13861 aaagtatcat aaaaatgctc ataatattct aaacttttat cactatattc tctacgttca
    13921 gaggtttctt ttgttatatt cttaaaaatc gatagttctt cacgttttaa ctttttcaac
    13981 cgaatgccaa aggtttcagc ctttttcacc aagggtttac cctttttgct aaaactttta
    14041 agcaaactct tttcagttaa ttcagttaaa tctttatagt ataaccaatc tggttctcca
    14101 cctgggtaac ctgttgttaa gccatcaaat tgataaccta aatcagtcaa accttgaata
    14161 atactttttt tctcagcatc tattggatta ccttggctat caaaagtttg ataagtttca
    14221 taaggtttta caagcaactc taatacacca ttttgcttgg catattcttt taactctgca
    14281 taaaaaactg gaagagcatc ttgttgggta taaatcggcc ccgaattgag ttccatatgc
    14341 agaccaccca gcatgggcaa gctataaacc agagctgcaa cttgaatttc tccttcttgt
    14401 ttcaaagcaa gataaacaat tcgagcccct cttttttcta gcaaatcccc catctggaca
    14461 gattgcataa aggaacgaga agaaacctga tcagaataag tctgaaactc ttctttcgtg
    14521 agtgttgtta gtgccatata cttactttct atgttttttt cttaatgttt tacggaaatc
    14581 aagagcaagt cttaacagag gatagagagg atgagtgggc attgtaaatt cacccaagta
    14641 ttcttcaatc gttggattaa atttttcctt aaaatgataa agtccaccat tgagagagtt
    14701 ttcaacacca cctaaatttt gccagaccat acctcgctca aaggcatagc gagccgtttc
    14761 ataccatgtt aaaattggtg cattgtaacg tttaaaatca tcatccatac cagcatatat
    14821 attgacagag gtagtaccaa attccaaact caaagtagcc gctaaaggaa ctctcgcttg
    14881 acctacatct atatattcct gcaagaaggt caattcctct aacaaacgtt ctttttcctt
    14941 cttctgcgct tctacttttg aagttcgagt cgactcagta aaggtctctt ccaaggctct
    15001 atttttcgct aactgttctt ctaactcttg cgaacgttta gaaacatcca aggtggccaa
    15061 ggtgatatag gccttgtcct taaaattatc taacaatttt ttataatagg cttcattcct
    15121 caaatgaatc tcttttcgct tctcagtttt tttcatcaac tccgaaaatg aatctaatag
    15181 ttccagtcca ccatattgaa tctcaagccc tttgtttcgt gctgttcgaa tagcctgttt
    15241 tgttgacttg gaaagtttat cttcttcaaa attttccttg tatattttcg cctgaatacg
    15301 aggttgaatg gtgtctccca tttcctccgt ttttcctgac caccttactc ccatttgttg
    15361 caaactatca ataatagcca gattttcagg aaattctgtc ttttcctgat tgattaaact
    15421 ttgagatagg caaatacttg ggtcaaaagt cacaaaaacc gctctcttac tgcgagcata
    15481 ggacttaata gactgaatgg caaaattcaa gagttcttta tccccataat ccaatatagg
    15541 tcctcttggg atgtaaaaca ttttatagcc tagcggaaga gttctaatca aaatactagc
    15601 tgtcgccagt aatttttctt ccctgtaaac accaaacttc tcatgttgcc aattagactt
    15661 aacttcctcc caagcactac tttgtaatac attggctaat tcatgttctt tgacaaactg
    15721 atcatattct aatgtgggaa tgccaatttg ataacggtac atttcctact ctctttcctc
    15781 cagtatttta ttactattct actactttcg tttgaaaagt ctagtgaaaa catattttat
    15841 tttagttcta ctccccctat gctgaagttc aaactaagtc agtctctctt ctaatttgaa
    15901 atcaattggt agggttgtta aaaaaacttc caattgtttt tcccagtagt accactcgtg
    15961 agttccagcg ctatggctat aggtcacatc aaaacctagt tttttgagat ttttcactgc
    16021 gagattattg gcttcgtaca agaaatcctg ttcgccacac cacgcccaaa gtttggtctt
    16081 tttatccgat tttttagcca gactttcaag agaataggga ctagttgtcc agtctctaat
    16141 ctctccaaaa acacctctcc agtaggctgg acttcccaga ttttgacttt caggagaaaa
    16201 gttttgaaag ctgagggcac ctgaaaaact agctgcatga gaaaaacgat ttgtcgcaag
    16261 agccagtttg aagcagccgt aacctcccat agaaagacca gcgataaagg tcttttcacg
    16321 cttgctagtc atattaggga agaagcgttt cagaacctgt ggcaattcct ctgctagagc
    16381 cgtgtagtag tcaaaaccat actgggtatc ggtgtaccaa ccattgctgg tattgggcat
    16441 aacaacgatg agattagttc ctcgaagcaa gcgttctaca ttggtccgct taagccaact
    16501 attatgattt ccagacatcc cgtgcaaaag gtacaagacg ggaatatctt cacactctgg
    16561 ttcttccact cgattggcat cagggtagag gacattcacc ccccactcca tatccaatac
    16621 ttgtgagtaa tactcgattt tcattactgc catgattttc tccttctatt tttctataag
    16681 aaaaagccga aactcgactt tctctctgtt tatttcaacg attattttgc ttccatgact
    16741 actggtaaaa tagctggacg acgcttggtt tggtcaaaga gatacttggt caaattatct
    16801 cgaaccttcc ctttaagatc tgcccagtca aagtcatctc cttgaagata atcttctacc
    16861 gtttggttaa tcaattctga actttcacgg agaatatcgc gactcttctt gagataaaca
    16921 aatccgcgcg tatgaacacg agccctagcc acaattttct tctcacgacg gttgactgta
    16981 atagccacga tgaaaattcc atcctctgac aagatcttac ggtcacgaag aacaacattt
    17041 ccaacatcac caatggcatt cccatcaatc aagatatctc ctgctgaaac cgatccagct
    17101 ggaacaaagt ctccattctc gtaagccatg gtcgtcccct ttttaggaat gaagatgtgt
    17161 tctggcaaca tcccaactgc catggcagcc ttagcgtgag catccaactc acgatactcc
    17221 ccttggacag ggaagaggta cttaggttgc aaaagattga tcatcagctg caaatcacgc
    17281 acatttccgt gccctgatac atgtaaactt tgggtaatca atttgacaac cccacctgcc
    17341 tgataaatca tattttccac acgcgcaaca aaggcttctt tagcaataga cggagccgta
    17401 gcaatataga ccaggtcccc atccttgatt tctacataac gatggcgacc aatcgacatc
    17461 ttacgaagtc cattgatagg ttcacccata cgacctgtct caagaataat caactcatgg
    17521 tcttcaaagc gagacatatc tttaggctta atcaagagaa tttcgttggc taaagacaac
    17581 ttcttaagac gaatcgctgt gcggacgata ttttcaatat caaatcctgt caagacgata
    17641 cgtcgacctg ttttatccgc agcgtcaaaa atctgctgaa tacgagaaag attactggaa
    17701 acagctgcaa cgatgatacg accttcccag tcagcaatag tttgggtaat ttcatcccta
    17761 acttcacttt cactagccac ctgaatattg ctgtctgcat tggccgaatc actgaggaga
    17821 gccaggacgc cgtcacgacc aatctctgcc aaacgagcaa aatcagttgc ataagattca
    17881 ctagccgttt ggtcaaattt gaagtcacct gtataaacga tgcttccttc cgatgtcttc
    17941 aagacaattc ccagactctc tggaacggag taagtcgtag ggaagaagga aaccactgtc
    18001 ccaccaaaat caatctccgt attctcatca atgacatgga aatcattaaa tttcttaacg
    18061 gcatcatttc ctttgacaaa gagctttgcc aactcaatgg tcaactcaga cccaaataca
    18121 ggaactttag cctctgccaa gagataaggt agagcaccaa tggcatccgc atgcccgtgg
    18181 gtcaagaaaa ccccagcaat acggtcgcta ttttcaaaaa ggtaatccat gtttggaatc
    18241 accacatcga cccctaattg ttcattttca ggatatttta accctacatt caaaacaaaa
    18301 atggactctc caatttcagc aatgtacata ttttttccat tctcacgcac accaccaagt
    18361 gttgttaaac tgatattact catttttcct ccaaaatctt agtttatctt gattataggg
    18421 caattctacc ctcttattct aaaagttctg atactttcag ccgaatcttt tcctaccatt
    18481 ataccatttt tttgatgatt ttcaaaatga aggtctgttt tcaaaaaaga gttgatttcc
    18541 caactctttc ctaacttcta ctctttttcc atcaaaaaat cataaatttc ttgcaccgta
    18601 cccagcgcca tcatttcttg gtctttaacg gtttgtttga gattttggta aatttgactt
    18661 tctcctatct cccgctttgg cgcctcttta ttgactgtca tcacaccatc ttttatcgtc
    18721 acaaagccta gttcttcaaa tacttgaatc atcttgacca gcaagatttg ttgaatatta
    18781 agatatgcag ccaaatcttt cagcttgtag cgaatatcaa actctgggaa ctggtaaata
    18841 gtcttgtaca atttagcaaa ctgatctcta gtcccataac ctgtcagata ataggtcttg
    18901 tcaatatcat ttttgaaata gacagcagag aaatgctgtt cctgaaaaat ggtcttcagc
    18961 tgagtaatat cctctggaat gttttttacg acaacagctt cactagccgc aagatttggc
    19021 agttctccag gaaaatccaa gactggaaca ccttctggca agactgcatt ttttccacga
    19081 atgttaaaaa gttgaacacc ttccactcgc gcatccacca tcatcaactg gagggcagtt
    19141 tggccattcc attggttgac agacaattta accgctaact ctagattctt ggtttgagaa
    19201 aactctgtcg cccatctgcc ttgaccaaag gctaccactt caaaactcgc ctcacccttg
    19261 gaaattttca gctttagatg ggcattacct gcccccatag tacgagcact ttcgacctga
    19321 aaattcttga tataaaaaat aggtttctga ttatccattc caaaaggagc taaacgttca
    19381 aaacttttga ccgtttccaa gctaagtgcc tccaaatcca actcttcatc taggtttaac
    19441 ttattcttgc caccagcatc tgcacctttt tcacgaacat aatcttccaa aacctgagat
    19501 aaatctgaga gttgctcaac ttccagcgtc atacccgctg cacctgcatg acctccaaag
    19561 gcgatgaaga ggtctcgatg gggatccaga gcttcaaaaa tatcgaccgc ttccacacta
    19621 cgagcactgc ccttggcacg accgtcttct atattaagaa caatgactgt ctgtcccaat
    19681 tcttccaata aacgaccagc cacgattcct agaaccccag gattccagcc ttccttggcc
    19741 aagacctgaa ccttcttctc aggatccacc atggtcttgg cttcttcata gatagactga
    19801 acgatttcct tgcgctcttc gtttttctgg tgaatcataa gggcaatctc atgcgcttcc
    19861 tcatcatcaa atccagtcaa caaatcaatg gcaggattgg gatcatccaa gcggcccaag
    19921 gcattcaaac gaggagcaat ctggaaacca accgtttctt ctgttacttc gttggcagca
    19981 atcccagcca tgtccagcat ttcttgcaga ccaatgcgct gggtatgacc caacatttcc
    20041 agaccatatt gaactaagat acgattttca tccgtcagac tcaccatatc tgcaatagtt
    20101 ccaatagcga ccaaatcaag caattccact tgcacttctt ctaacagggc acaagccaac
    20161 ttgaaagcaa ctccacaacc agccaaatat ttaaaaggat aatccgcatc tggatgttca
    20221 ggatggacaa tagcataagc atctggcagg gtttcaggca tggaatgatg gtctgtcaca
    20281 atgacatcta ctcccataga ctgagccaat gcaatagcct catgaccagc aaccccattg
    20341 tccaccgtca caatcaagga aattccttct tgctcgataa agtatttata aacactagca
    20401 ttagggccat agccatcggt aaaacgattt ggcaggtaaa ctcggcactc agcaccaagt
    20461 tgttccaaac tttccttcac aatagaagcc gaagtcatgc catccgcatc atagtctcca
    20521 taaacgagaa tattttcccc ttcttcaata gcctgacgaa tccgctccac tgccttgtcc
    20581 atatcatgga gcagataagc atcatgtaag tcctccaagg aaggttctaa aaacttcttc
    20641 agactttctt ggtcctgaat ccctctctca aacaataacc gagccacctc aggacccagt
    20701 ccagccttct tggctatctt tgtaaaatcc gcatcttcta cctgcagggc aaactgccat
    20761 tcataagtag gtgttatcaa aaagacatcc actctttcta agaattctat tgcttcatta
    20821 taacatgatt tagacgtttt ctctatccag attgcttttt tataacattt tatagtatat
    20881 tgaaactaga atagtacacc tctacttcta aaatattgtt agaaatcgat ttgactgtcc
    20941 cgatcgattt gtcctgttct tatttcacta tagtgaattt tttcagatat ggtttgacaa
    21001 gaacattctt tcattgtaga atcgtgttat aaaatataac acaaaggaga tctctcatgg
    21061 ctttagtaga atttaaaaac gtcgaaaaat attacggaga ctaccacgca ctccgcaaca
    21121 tcaatctccg ttttgaaaaa ggacaagttg ttgtcctgct tggaccttct ggctctggga
    21181 agtccactct tatccgtacg atcaatggtt tagaggctgt tgacaaagga agtctcctag
    21241 tcaatgggca ccaagttgct ggtgccagcc agaaagattt ggtacctctt cgcaaggaag
    21301 tcggcatggt ttttcaacat tttaaccttt atccacacaa aacggtgtta gaaaacgtga
    21361 cacttgcgcc cattaaagtt ctaggaattg ataaaaaaga agctgaaaaa accgcccaaa
    21421 aatatctgga atttgtaaat atgtgagaca agaaagattc ctatcccgcc atgctatctg
    21481 gtggacaaaa acagcggatc gccatcgctc gtggtcttgc tatgcatccg gaactcctcc
    21541 tctttgatga accaacatct gctcttgatc ctgagactat cggagatgtt ctagcagtta
    21601 tgcagaaact ggcgcatgat gggatgaaca tgatcatcgt tacccacgaa atgggctttg
    21661 ctcgagaggt tgcggaccgc attatcttta tggccgacgg agaagtttta gtagatacga
    21721 cagatgtcga taactttttt gacaatccaa gcgaacctcg tgcccaacaa ttcctcagca
    21781 aaattatcaa ccacgaaagt gacaaagtca aataaggagg cgcctatgaa aaaaaattct
    21841 ttttatcagc attattgatt agccttttcg gccttgctgc tgccaaacca gtccaggctg
    21901 atactagtat cgcagacatt caaaaaagag gcgaactggt tgtcggtgtc aaacaagacg
    21961 ttcccaattt tggttacaaa gatcccaaga ccggtactta ttctggtatc gaaaccgact
    22021 tggccaagat ggtagctgat gaactcaagg tcaagattcg ctatgtgccg gttacagcac
    22081 aaacccgcgg cccccttcta gacaatgaac aggtcgatat ggatatcgcg acctttacca
    22141 tcacggacga acgcaaaaaa ctctacaact ttaccagtcc ctactacaca gacgcttctg
    22201 gatttttggt caataaatct gccaaaatca aaaagattga ggacctaaac ggcaaaacca
    22261 tcggagtcgc ccaaggttct atcacccaac gcctaattac tgaactgggt aaaaagaaag
    22321 gtctgaagtt taaattcgtc gaacttggtt cctacccaga attgattact tcccttcacg
    22381 ctcatcgtat cgatgccttt tccgttgacc gctctattct gtctggctac actagtaaac
    22441 gcacagaact actagatgat agtttcaagc catctgacta cggtattgtt accaagaaat
    22501 caaatacaga gctcaacgac tatcttgata acttggttac taaatggagc aaggatggta
    22561 gtttgcagaa actttatgac cgttacaagc tcaaaccatc tagccatact gcagattaag
    22621 gaggacaccc catgatagat ttatcatctt ggacagccta ttttcaggat tttggacaat
    22681 ttttcaatgg tttcctcttt actcttgccc tagcgattgg atcctttatc ctcgccatgg
    22741 tcttaggaat cttctttggt gccatgtcaa ccagtaaacg tccaatttta cgcattttag
    22801 ctcacatctt tgtggaattt taccaaaaca ctcccctctt ggtgcagttt gttattgttt
    22861 tttatggcct acctcttatc agtgaccata ctatcatgat tccaatttat tggacagctg
    22921 ttctctgcat gggactctat cacggcgctt atatcgctga ggttattcgt tcagggattc
    22981 agtctattcc tagtggtcag atggaggccg ccttgtcgca aggttttacc tatatcagtg
    23041 ccatgcgctt gattatcttg cctcagacct tccgcatcat tctccctcca ttgaccaacc
    23101 aaattgttaa cctcatcaag aacacctcta ctgtagctat catctctgga gtagacttga
    23161 tgtttgtgac taagtcttgg tcggctctca acggaaacta tatcccagcc tttttaggtg
    23221 ctgctcttct ctactttgct ctatgcttcc ctgttgccca gtttggtcgc aagatggagc
    23281 aagccaacaa aaaagcctat tcactttagg aggttactat ggaatctatt ttagaagttt
    23341 taaccccaga taacctagtc tttatcttta aaggatttgg cttgaccctc tatatttctc
    23401 tgattgccat catcctctct actatcatcg gtacggtgct agctgtcatg agaaatggca
    23461 aaaatcctgt cttacgcatt atttccagta tttatatcga gtttgtgcgc aacgttccca
    23521 accttctctg gatttttact atctttttgg tgttcaaaat gaaatccaca ccagcaggta
    23581 ttacagcctt tactctcttt acatcagcag ccttggctga gattattcga ggcggtctca
    23641 ataccgtaga caagggacag tacgaagcag gaatgtcaca aggcttcacc tcagcccaaa
    23701 tcctctacta catcattctc ccacaagcca tccgcaaaat gctaccagcc atcatttctc
    23761 agtttgttac cgtgattaag gataccagtc tcctctactc tgttatcgcc ctacaagaac
    23821 tctttggagc cagccaaatt ctcatgggcc gttatttcga accagagcag gtcttcagtc
    23881 tttgcatcct gattgccctc atctacttca gctttaacct agcaatttct agcctgtctc
    23941 atatgctagc caaacgttgg caacaagctg cagaataata ctcttcgaaa atctcttcaa
    24001 accacgtcag cttcaccttg ccgtatatat gttactgact tcgtcagttc tatccacaac
    24061 ctcaaaacgg tgttttgagc agcctgcggc tagcttccta gtttgctctt tgattttcat
    24121 taagtataaa cagccactct ccagttcaat tggagagttt tttgatgaga gtagatattt
    24181 atagacctca atttgacacc atacattttc tatgataaaa tgtaacaaat tcatttacaa
    24241 caaatcgaaa tctaaatgaa atggaatttt ctatgaaatc agtcaaagga ctactcttta
    24301 tcatagctag ttttatcttg actcttttga cttggatgaa cacttctccc caattcatga
    24361 ttccaggact agctttaaca agcctatctc tgacttttat cctagccact cgtctcccac
    24421 tactagaaag ctggtttcac ggtttggaga aggtctacac cgtccacaaa ttcacagcct
    24481 ttctctccat catcctacta atctttcata actttagtat gggcggtttg tggggctctc
    24541 gcttagctgc tcagtttggt aatcttgcca tctatatctt tgccagcatc atccttgtcg
    24601 cctatttagg caaatacatc caatacgaag cttggcgatg gattcaccgc ctggtttacc
    24661 tagcctatat tttaggactc tttcacatct acatgataat gggcaatcgt ctccttacat
    24721 ttaatcttct aagttttctt gttggtagct atgccctttt aggcttacta gctggttttt
    24781 atatcatttt tctatatcaa aagatttcct tcccctatct aggaaaaatt acccatctca
    24841 aacgcttaaa tcacgatact agagaaattc aaatccatct tagcagacct ttcaactatc
    24901 aatcaggaca atttgccttt ctaaagattt tccaagaagg ctttgaaagt gctccgcatc
    24961 ccttttctat ctcaggaggt catggtcaaa ctctttactt tactgttaaa aattcaggcg
    25021 accataccaa taatatctat gataatcttc aagccggcag caaagtaacc ctagacagag
    25081 cttacggaca catgatcata gaagaaggac gagaaaatca ggtttggatt gctggaggta
    25141 ttgggatcac ccccttcatc tcttacatcc gtgaacatcc tattttagat aaacaggttc
    25201 acttctacta tagcttccgt ggagatgaaa atgcagtcta cctagattta ctccgtaact
    25261 atgctcagaa aaatcctaat tttgaactcc atctaatcga cagtacgaaa gacggctatc
    25321 ttaattttga acaaaaagaa gtgcccgaac atgcaaccgt ctatatgtgt ggtcctattt
    25381 ctatgatgaa ggcacttgcc aaacagatta agaaacaaaa tccaaaaaca gagcttattt
    25441 acgaaggatt caagttcaaa taagtaatca tactctcctg ggatttccca ggagagtttt
    25501 ttatagccaa atgaaataaa accggaacga tggaattttg gcattcaaat caattgataa
    25561 gaatatttta tagtggagtg aaataggata cgaacaaatt gattaggaaa atcaaatgaa
    25621 tttatagaaa tcttttagca gttatgttgt cctattctag tttcaaaacg ctatagaagc
    25681 agcattgtgc tagtctagat tcagtttact atactaaaac gagtagcttg aaatcaaaaa
    25741 acccaccctc acaggcaggt tttatctgta ttattcagct agattatgct ttaccttctg
    25801 aaccgaatac gtcgatacgt tcttcaaccg atgcttggat agcttttaca ccgtcagcca
    25861 agaatttacg tgggtcgaag agttttttct tgtcgtattc tgcttcgttt gcttcgtagt
    25921 cacgagcaaa tttacgagtt gcgttagcga atgcgatttg gcattctgtg ttaacgttaa
    25981 ctttggcaac accaagtttg atagctgctt ggatttgctc atcaggaata cctgatccac
    26041 cgtgcaatac gattgggaat cctggaagag cttctgtcaa tttttgcaag tggtcaaggt
    26101 caagaccttc ccagtttact gggtaagggc cgtggatgtt accgatacca gctgccaaga
    26161 agtcgatacc agtttcaacc attgctttag cgtcttcgat tggagccaat tcacctttac
    26221 cgatgattcc gtcttcttca ccaccgatag taccaacttc agcttctact gagatacctt
    26281 tagcgtgtgc tttttcaaca acttctttag ccaatttaag gttttcttca actggaaggt
    26341 gtgaaccgtc aaacatgatt gaagtataac caacttcgat acactcaagt gcatcttcgt
    26401 agtgaccgtg gtcaaggtgg atagctactg gtacagtgat acccattgat tcaacaaggt
    26461 tagcgatcaa gttgcgagca actttgtaac cacccatgta tttagcagca cccattgaag
    26521 tttggatcaa aactggagct tttttagctt ctgctgcgcg caagatagct tgagtccact
    26581 caaggttgtt tgtgttaaat ccaccaactg cataaccgtt gtcacgggct gcttggacaa
    26641 atttttctgc tgaaacgatt gccattttat caggcctcct gtatattttt atgggtcatc
    26701 ccatttacat tgttcatttt atcacttttt gccaaaaaaa tctagttttt cccgcagttt
    26761 cgattgattt tcttctaact ccatctatgt aaaccctttc tctccctagt cttggacgac
    26821 ttttggaaaa tctataaaga aggttaaacg attctcctcc atctcgaaac gataagctaa
    26881 tttttcatgt tctaatagac tcttaaccac aaagagcccc ataccagacc ccttgacctt
    26941 gcgactggca ttgtcagaaa aagactgggc tagtttttct tgttcctctg agctacagct
    27001 attttcgata aaaagttctc cttctctttc tccaattcga actaagccac ctggaacaga
    27061 gtgcttaatg gcattgctga tgagattaga aagaatcaac ttcataactg atgggtttag
    27121 ataagcctgc tgatgggtca aactattgtc tatctggagc tctctttcct tggctagcaa
    27181 ggcataatct ttgaccagat tttgcgtcat ctggaggagg tcaattgttt ccctatcatc
    27241 tcgcaattcc tgcacagaag agagggaaag tatctgcaga acatggtgat tgagttcatc
    27301 cacaatcccc aaggcaactc ccagatactg gtctctatcc ttataacgac cgatattctc
    27361 tctcatattt tcgattagga ttttcaaact agccagcggt gttttcaatt catgagaagc
    27421 tcctcgtagg aattcgacct tcatcttctc cagctggaga atggcttcat tcttttcatg
    27481 caagtccgca ataacagtca agagatgctg gtagaggcta ttgatttgtt ccttgagatt
    27541 acctatctca tccttagaat ccacgcgcaa tcgcacttgg gaatccaggt ccatcatccg
    27601 acgggtcacc cgcttgattt ccaagatcgg tgcaacaata gtccgagcgt agatgtaggc
    27661 caccaagagg gaaatcagaa aggaggccag caaggtatag ggaagaaact ggagactgat
    27721 ttgctccgct tccttttgta aatccatgga agctagaaac tggagaatca tagtagcacc
    27781 gtcttgcgtt ttcacctcgc gctcctcaat aaagagagag gttgtctggc ggtctgtgtc
    27841 cagaggaaga ctgtccttga cttctaactt gtcctcggtc atctcacctt tgacggtccc
    27901 cttgatatca ctagtctggg aatacaagtc taacacttgc tcgatactct gcctatcttt
    27961 cccttctagg gactgggcaa tggctgttgc cttttgacca atggtttcct gacgatgact
    28021 cagataagtc gaaggaaaaa gaaaataaat agctaaatga aggcagataa ccagaacact
    28081 aaatatcgag aaggtataga taaatatctt tgcaaataaa cctgttcgtt tcattttcgc
    28141 tccaatttat aaccaacatt gcgcacagtg aggatacaat ccaagtctag ctttttccgc
    28201 aattccttga tataaacatc aataacacgg tcaaagggaa cctcatctgt cgctttccag
    28261 acggcatcga taatctgaga tcgagtcaag gcccggcctt catttttcac tagatagtcc
    28321 agaatttcca actctttggc attgataggc acttcttgac ctgcgatgct tgcactgtag
    28381 ctttcaaagt ccaccttggt atccttgtaa gaaaagattc gtcctgtatc gtagtagcgc
    28441 ttgaaaatcg cgtccaccct cacttttaaa agggagaggg agaaaggttt ttccagatag
    28501 ccatctgcca aagaggcaaa ggcactcatc ttgtattcct catcttgaaa agctgtcaac
    28561 atcaagacag gaacctgact ggttttacga atctcagcta ggacttctaa gccgttgagc
    28621 ttgggcatct ggatatccag taaaaccagg gccacctcat agctagaaaa ttgctccaga
    28681 gcttcctgac cgtccgctgc ctcaatagtt tcatagccac aatccgtcaa ataatcactg
    28741 accccctcac ggatcatctc ttcatcttct acaattaaaa ttttcatact ttaactgctc
    28801 tctatttttt atttttctta gaataaatac ctactctatt ttctattata gtctcttgct
    28861 ggccttttgt ctgcaagcaa ctgaccacta gataaaacgt tgtgaaattc ctttctcata
    28921 aattccataa ctttagtata ttatatttaa gcactaaagt acaaagaaag caactgaaag
    28981 caatgatttt caccactgct ttcggattta ttttgaattg ttaaatagcc attcctatcc
    29041 actattcttg aatagaaaca caagatgcaa tctttattct agactcattt tttcaaattt
    29101 attcaccatc cagcaagagc tcttttggtt gttttctaag gagattgctt gaagcaagcg
    29161 ccataacgag aaccactaga accaaggcaa ggacaaaaat gatgataaag tctgatgtct
    29221 gaatggaaat gtctaggctc gacaaggtct tgctaaagcc atctacttct gcaccaccac
    29281 caaggttaga ggcttgagcc gccttactag cctgtttggc aacacctgaa gtcacattgg
    29341 caaggacagt gtttccaatt gcacgggcag tgtaattagc taggaagtaa gcagaaacta
    29401 gagcagggat agcaatcaag atagattcgg tgatgaattg acccaagata cttgcctgct
    29461 tgaggccgat agagaggaga attcccactt ccttgcgacg ggcgttgatc caaaggctga
    29521 gcaagagggc aaggaggaga actgagaagc tcaagctacc ccagaagagg aggttggcca
    29581 tcttgtacat accagagata gattgctcaa gagctgggta gttagaggag ctcttgacga
    29641 gtgtgtagct cttccagttg ataccactga tgccattcaa ctctttcata acatcatcca
    29701 agttcttgtc tgctgttaca aagaaggttg cgtccccata aatggctgtg tcttctgtgt
    29761 atccataaag ttttgcagca gtgtgaatgt ctgtaatagc tgtgttttcg taaagttctt
    29821 gtgagtaggt tactgctgac ttattatgac catcaaagag tcccttgatt gtcacttcaa
    29881 ctgtttcctt ggctcctttt tcattatctg catcgtagat attagagtcc agtttaacct
    29941 tgtcccctac tttccagccg tgtttggctg ccaagtcctt gtgcaagagg attttatcct
    30001 tgtcgtcgtt ggttaagtgc tctccttcga ctagtttata agaaccagag acaaacttgt
    30061 cttctttaga ggagtcattg acacctgtaa tcatcaagct acttccaaaa cgcttggcac
    30121 gatcagcagt gagattcttc ttggtttctg gcgtttcaat caggtcatat ccagtcaaat
    30181 ctccgatagc gttgatacgt ttgacataag actcgatggc cttgttttcg gtgatttttt
    30241 tgatgtcttc acccttgata ttcccagcac cacgaggcgt tccttggttg acgcgacgat
    30301 tgatttgcat ggagaagcta ttagtgatat ttttaaaggt ctcctgagaa gccttggcag
    30361 tagctccctt gattgacaag ccgaccaaac tcaagctcgc catgaggaga ataatcagga
    30421 agatgacaat cgatttgaaa aacttccttg taacataggc aaatgcgttg tgtaacatag
    30481 attccctttc tagattttgt tttaatcatt ctatcaaaat aagctcaaat tatttactag
    30541 tattgcgcgt ttcagtcagt ttcttatcct ttaattcaag tgtaatatct gacgcttgtg
    30601 ccacttcttt actgtgagtt acgacaatca cacatttacc tgttttctgg gcaagtgatt
    30661 tgagtagttc gacaatatct ccagcagttt taggatccag atttcctgtt ggctcatcag
    30721 ctagaataac tggagcttct gagaccaaac tgcgagcaat ggcaacacgt tgctgttgac
    30781 cacctgataa ctggagaaca ttccgcttga tctggctttc atccaaacca agctcaagaa
    30841 gtgtatcctt gcttgccttt ttgttgacca agcggatatt ttccagcgga gaaagataat
    30901 ctatcaagtt ataattttga aagaccaggg aaatatggtg catgcgatgg taagaatagc
    30961 ccttcttacg aatatcctct ccttgaaaaa ggatagaacc ttcaacagga ctatctagac
    31021 cagcaagtag ggacaagagt gtggattttc ctgctcctga ctccccaata atactgtaaa
    31081 attttccagg ttcaaaatta taatcgatct gatataggac tgcttcagca gtattcttat
    31141 aacggtaggt aacatcttgt aattgtaata aagtcatgat ttctccttct taactaatag
    31201 atgataaaat ttctttcggt gattttctaa ataagaatag gaaacaaagg gctacagata
    31261 agcaactaag cagaactaga aaaacatagg attctgcaaa agataagatg ctagttgata
    31321 aactgcttgc tttggctagt gtatcttgta agcttgcctg atctccactt gctagtagag
    31381 tttggagtag ataacttgtg attccgtttc ctgcaacaaa tgctggaagc aaagctccaa
    31441 gagataccaa aactacctct aaacagaatt gtaggaagat cgagctcttg ccttttccaa
    31501 gtgcaagtaa aatccccact tcatagaccc gttctctcaa ccagagagac aaaaccagaa
    31561 ttaaggctcc agctcctgct atcaacatcc cataaaggaa gatggtcaag aaggtttgga
    31621 aagttgcaac tgagtctttg atttgttcaa aagccttgtt ttccttttcg acttggtagc
    31681 cttgattttc caaggccaag ttttctacct gcttcatgag tccgtccatt tccttaggat
    31741 tttctacata gaagcgtgct gcactgactt gagcttcact attgcccaaa agggtttggc
    31801 tactttcata gtctgtaaag acttgatttt cactgaagtc agaagacaag cctgtgaatt
    31861 tctcttgttt tttaccagaa aagatgccga taatctcaaa ctctactgtt tgtccttttc
    31921 cagattcaga ctgaccagca tccaagccaa tcttgtcatg aagtgaaaga ccgttcttct
    31981 tagccaattc ttcgtggata aggattttct tggaatcccc tttttgaagg tgtcgccctt
    32041 cttttagatt gaaagccgaa ctggtaaagg ttacatcctt ggatgaatcc tcaagagccg
    32101 ttaagctaac caagttattg tctgcagctg ataaatcatc acgctccacg ctctgctcac
    32161 cagtcactgc ttccttgtct tttagttttg cgaccgtctc aagttcagga gagacatttt
    32221 ccagcccctt aatcttgctt acagatgcta ggtctgacaa cttgaatgtc tgaccattct
    32281 ctatcttctt aatagaaaaa gatgtattga gtgatttata aagattgctt tctactgttt
    32341 tgttggactt catcagagtc aaacaggctg aaattccggc caataagacc aataaaatca
    32401 gaaataaaat aaaacttctc agtcgctttc tgctgacata agcccaagat ctttggattg
    32461 gattcatttg tcacctccat atttgtaaga ctattataaa acccaaatat gaaatgttta
    32521 tgaaatacga aaaaaaatat cgagtagggg ataatctcta gcccctctca cac
//
LOCUS       DAVBDR010000018        32366 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.018, whole genome shotgun sequence.
ACCESSION   DAVBDR010000018 DAVBDR010000000
VERSION     DAVBDR010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 32366)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32366)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32366
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.018"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            150..488
                     /locus_tag="VQ540_000867"
     CDS             150..488
                     /locus_tag="VQ540_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000176371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="HET2544692.1"
                     /translation="MTLTIHVYYKGDGDCAIKFAREMLESGLVAEIRCQKGNLKYEYF
                     LPIEKEGIILLIDQWINQEALDEHHQSNTMQKILDLRKKYHLQMQVERYIEDDSGMPE
                     SDKSFIDTGN"
     gene            678..2114
                     /locus_tag="VQ540_000868"
     CDS             678..2114
                     /locus_tag="VQ540_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HET2544693.1"
                     /translation="MTTFKDGFLWGGAVAAHQLEGGWQEGGKGISVADVMTAGRHGVA
                     REITLGVLEGKYYPNHEAIDFYHRYKEDIALFAEMGFKCFRTSIAWTRIFPKGDELEP
                     NEEGLQFYDNLFDECLKNGIEPVITLSHFEMPYHLVTEYGGWKNRKLIDFFARFAEVV
                     FKRYKDKVKYWMTFNEINNQANYQEDFAPFTNSGIVYEEGDNREAIMYQAAHYELVAS
                     ARAVKIGHEINPDFQIGCMIAMCPIYPVTCNPKDILMAMKAMQKRYYFADVHVLGKYP
                     EHIFKYWERKGISVDFTDQDKEDLLGGTVDYIGFSYYMSFAIDSHRENNPYFDYLETE
                     DLVKNNYVKASEWEWQIDPEGLRYALNWFTDHYHLPLFIVENGFGAIDQVAADGMVHD
                     DYRIEYLGAHIREMKKAVVEDGVDLMGYTPWGCIDLVSAGTGEMRKRYGFIYVDKDDN
                     GKGSYNRSPKKSFGWYKKVILSNGESVE"
     gene            2166..2405
                     /locus_tag="VQ540_000869"
     CDS             2166..2405
                     /locus_tag="VQ540_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000580385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SemiSWEET family sugar transporter"
                     /protein_id="HET2544694.1"
                     /translation="MIGSIAAILTTFAFLPQVFRVVKTKDTGSIALGMYVMQVIGIAL
                     WLAHGIRIGDLPLILANSVSFLLSGIILFYKLKYK"
     gene            2535..2849
                     /locus_tag="VQ540_000870"
     CDS             2535..2849
                     /locus_tag="VQ540_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003037418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIB"
                     /protein_id="HET2544695.1"
                     /translation="MAKALIICAAGMSSSLMAQKTTEFLKGKGKDIVVDAISATEGGK
                     AIAAAAFDLYLVSPQTKMYFKQFEEAGSKAGKPVVQIPPQAYIPIPMGIEKMANLILE
                     NI"
     gene            2967..4946
                     /locus_tag="VQ540_000871"
     CDS             2967..4946
                     /locus_tag="VQ540_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001101767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HET2544696.1"
                     /translation="MNVLNIKEKDILQFLIKNKERFVTSKELAEYLSCSDRTVRNVLK
                     LIEKTMIIQGVRLISKQGQGYQIFFENQGAYQEFRQTYELEEDYTKTAVSKGDDRLVF
                     ILNKLLFEQVPVLFDDLADELYVSRSTLSHDFRKIRVMLSEYNLSIESRANKGVYVSG
                     EERDKRRFIINYFLENQFFKTIHCYVKFNFFAQTVPLEEFARIVLDECQEANLKLSDF
                     VLQNLVVHIALSVIRLKSGFEIKNIDCQMTDDAIERKVAQRILSKVREVTNQEFPVQE
                     IDYITLHLLAKSQQCQKNQKNISEEVLKKSLFKTFQNLGLDDMYNFSSDFQLIEGLIT
                     HLMTLQVRLESRITLNNPLVDEIKQNYSDIFFMTREILANMDKFLEWTISDDEVAYVS
                     LHFLAAMERSKESTKFNILAICATGFGAAQMLRNRLETEFGKRVEVVDVIGYYELNQE
                     KLKGIDFIVSAVDLSNLYFQIPVFKVSVFLKSDEMEMIRKAMDQMQVSSYVQSSKINK
                     FENNSFRQYFSKENFLICTESDKVNLLEKMVESLSVGESNEFEQSLLYGIKQREELSS
                     VVFSEKIAVPHPIQPFGTEGKVSVAICKDSLLWDNQSSYVQLVFLLSPSIYGNEGLAT
                     VTKKIVSLTENDELQNQLISCNNFEDFISIFEKIK"
     gene            4956..5270
                     /locus_tag="VQ540_000872"
     CDS             4956..5270
                     /locus_tag="VQ540_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001070943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIA"
                     /protein_id="HET2544697.1"
                     /translation="MNQEELQVAAFEIILHSGNARSEIHEAFAKMREGSFDDAESKLN
                     QSNEIILEAHHAQTKLLQEYASGVEIKIEIIMVHAQDHLMTTMTLLEVAKEMLALYKK
                     VN"
     gene            5301..5807
                     /locus_tag="VQ540_000873"
     CDS             5301..5807
                     /locus_tag="VQ540_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2544698.1"
                     /translation="MDKKERQKIEQQRREMALTNTFFNRYLLLRYSIALFFFGNIYWL
                     LNQFINPSPIIIFPIMLIVFSILATVEQFKLYGNRKEKLGITLMFVRIQILISIGLLV
                     LTWTSWFKNLFPIFENNQVARLFVFVVLLLGLVLSLLDIRRIKKIYKRTDKAYQQFVQ
                     LEKNSLSL"
     gene            5887..7233
                     /gene="celB"
                     /locus_tag="VQ540_000874"
     CDS             5887..7233
                     /gene="celB"
                     /locus_tag="VQ540_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HET2544699.1"
                     /translation="MDQQNGLFGFLENHVMGPMGKLAQFKVVRAITAAGMAAVPFTIV
                     GSMFLVFSILPQAFSFWPIVADIFSASFDKFTSLYMVANYATMGSLSLYFVLSLAYEL
                     TKIYAEEEELNMNPLNGALLALMAFVMTVPQIIFDGGMMKTVTSLKEGAVIADGWAMG
                     NGVARFGTTGIFTAIIMAIVTVLIYRMCVKHNWVIKMPEAVPEGVSRGFTALVPGFVV
                     AFVVIFINGLLVAMGTDIFKVIAIPFGFVSNLTNSWIGLMIIYLLTQLLWIVGIHGAN
                     IVFAFVSPIALANMAENAAGGHFAVAGEFSNMFVIAGGSGATLGLCLYIAFASKSEQL
                     KAIGRASVVPALFNINEPLIFGLPIIYNPALAIPFILAPMVTATIYYVANSLNFIKPI
                     IAQVPWPTPVGIGAFLGTADLRAVLVALVCAFAAFLVYLPFIRVYDQKLVKEEQGI"
     gene            7613..7789
                     /locus_tag="VQ540_000875"
     CDS             7613..7789
                     /locus_tag="VQ540_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2544700.1"
                     /translation="MSLDIDKEKMTIMGIAFENRSVFKSVWYALSTNMIEGWRPTVSD
                     VEKLRDEALALGMT"
     gene            8199..10412
                     /locus_tag="VQ540_000876"
     CDS             8199..10412
                     /locus_tag="VQ540_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000688702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-xylosidase"
                     /protein_id="HET2544701.1"
                     /translation="MKIFKGEFYRISVLTDKLVRLEYSQTGSFEDRTTQLIYNRDFGQ
                     VSLDYIETSNVLDIMTDYFHLHFNKGEFNAENLFIELKGNFAVYGSRWYFGESIETLK
                     GTARTLDKADGAISLEDGIISRNGIALLDDSQGFIWDEQSGYIERENQIDLYFFAYGH
                     DYRGAIRDFYHLTGSTPLLPRYALGNWWSRYWPYTSDEYLDLIDRFETEKIPLSIGVL
                     DMDWHITDIPARFGSGWTGYSWNRNLIPNPEQLLQQLHDRKLKLSLNVHPADGIRAYE
                     EAYPQIAKRLGLNVELEEPAIFDFFNPSFREAYFKDVHYELEKQGVDFWWIDWQQGTQ
                     GMLDPLWLLNHYHYQDSCKNAEGGLILSRYAGPGSHRYPVGFSGDTIISWNSLRFQPY
                     FTATASNIGYSWWSHDIGGHMLGDYDEELQTRWLQFGVFSPITRLHSSRSPFNSKEPW
                     FFSETTSKIMKKYLRLRHQMIPYLYTMNVKTHEEGAPLISPIYYFYPENDESYNVPNQ
                     YFFGTELMVAPIVEKMDLTFQSAKVDVWFPEGEWYDFFSEKKYTGGVKLSVYRDISTT
                     PVFAKSGAIIPLVGSEIGMGVDLPEVVDWYVFPGKQHFFEMLEDQNGQRYKTRLSIDW
                     EMGMVELALQGDSSIVPSNRKHRIHFKGTNVSIIELPNKNDTAKFEWKDNKRTSLNDE
                     VFRLLKTASLPYELKDRLLNQFINAKNSHDLMNILHHQDKELRGRLLEMIFTSQN"
     gene            complement(10634..11110)
                     /locus_tag="VQ540_000877"
     CDS             complement(10634..11110)
                     /locus_tag="VQ540_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HET2544702.1"
                     /translation="MTSLYDFSVLNQNNQATPLDSYRGKVLLIVNTATGCGLTPQYQG
                     LQELYERYQDQGFEILDFPCNQFMGQAPGSAEEINAFCSLHFQTTFPRFAKIKVNGKE
                     ADPLYVWLKDQKSGPLGKRIEWNFAKFLIGRDGQVFERFSSKTDPKQIEEAIQTLL"
     gene            11333..14533
                     /locus_tag="VQ540_000878"
     CDS             11333..14533
                     /locus_tag="VQ540_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored hyaluronate lyase"
                     /protein_id="HET2544703.1"
                     /translation="MQTKTKKLIVSLSSLVLSGFLLNHYMTVGAEETTTNTIQQSQKE
                     VQYQQRDTKNLVENGDFGQTEDGSSPWTGSKAQGWSAWVDQKNSADASTRVIEAKDGA
                     ITISSHEKLRAAVHRMVPIEAKKKYKLRFKIKTDHKVGIAKVRIIEESDKDKRLWNSA
                     TTSGTKDWQTIEADYSPTLDVDKIKLELFYETGTGTVSFKDIELVEVADQPSEDYQTD
                     KQLEEKIDLPIGKKHVFSLADYTYKVENPDVASVKNGILEPLKEGTTNVIVSKDGKEV
                     KKIPLKILASVKDAYTDRLDDWNGIIAGNQYYDSKNEQMAKLNQELEGKVADSLSSIS
                     SQADRTYLWEKFSNYKMSANLTATYRKLEEMAKQVTNPSSRYYQDETVVRTVRDSMEW
                     MHKHVYNSEKSIVGNWWDYEIGTPRAINNTLSLMKEYFSDEEIKKYTDVIEKFVPDPE
                     HFRKTTDNPFKALGGNLVDMGRVKVIAGLLRKDDQEISSTIRSIEQVFKLVDQGEGFY
                     QDGSYIDHTNVAYTGAYGNVLIDGLSQLLPVIQKTKNPIDKDKMQTMYHWIDKSFAPL
                     LVNGELMDMSRGRSISRANSEGHVAAVEVLRGIHRIADMSEGETKQRLQSLVKTIVQS
                     DSYYDVFKNLKTYKDISLMQSLLSDAGVASVPRTSYLSAFNKMDKTAMYNAEKGFGFG
                     LSLFSSRTLNYEHMNKENKRGWYTSDGMFYLYNGDLSHYSDGYWPTVNPYKMPGTTET
                     DAKRADSDTGKVLPSAFVGTSKLDDANATATMDFTNWNQTLTAHKSWFMLKDKIAFLG
                     SNIQNTSTDTAATTIDQRKLESSNPYKVYVNDKEASLTEQEKDYPETQSVFLESSDSK
                     KNIGYFFFKKSSISMSKALQKGAWKDINEGQSDKEVENEFLTISQAHKQNGDSYGYML
                     IPNVGRATFNQMIKELERSLIENNETLQSVYDAKQGVWGIVKYDDSVSTISNQFQVLK
                     RGVYTIRKEGDEYKIAYYNPETQESAPDQEVFKKLEQAAQPQVQNSKEKEKSEEEKNH
                     SDQKNLPQTGEGQSILASLGFLLLGAFYLFRRGKNN"
     gene            14913..15298
                     /gene="tnpA"
                     /locus_tag="VQ540_000879"
                     /pseudo
     CDS             14913..15298
                     /gene="tnpA"
                     /locus_tag="VQ540_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005816675.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            complement(15677..16306)
                     /locus_tag="VQ540_000880"
     CDS             complement(15677..16306)
                     /locus_tag="VQ540_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HET2544704.1"
                     /translation="MTKSDTIIELKKQKIVAVIRGNTKEEGLQASIACIKGGIKAIEI
                     AYTNQYAGQIIKELVDLYQDDQSVCIGAGTVLDAVTARDAILAGANYVVSPSFHAETA
                     KMCNLYSTPYIPGCITLTEITTALEAGSEIIKLFPGSTLSPAYISAVKAPIPQVSVMV
                     TGGVGLNNIPQWFAAGADAVGIGGELNKLASQGNFDRISEIAQQYITLR"
     gene            complement(16316..17317)
                     /locus_tag="VQ540_000881"
     CDS             complement(16316..17317)
                     /locus_tag="VQ540_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HET2544705.1"
                     /translation="MTKILLFGEPLIRISPLDATSIGDHVASSTYFGGSEINIACNLQ
                     ALGISTKVFTALPANEIGDRFLTFLKQHQIDTSSICRLGDRIGLYYLENGFGCRQSEV
                     FYDRKHTSISQIRPNMLDMDSLFQGISHFHFSGITIAIGQEVRAILLLLLEEAKRRGI
                     VVSMDLNLRTKMISVLEAKYEFSKFARFTDYCFGIDPLMIDDQNLEMFPRDSASLEEV
                     ENRMRLLKEAYGFKAIFHTLRSSDEQDKNVYQAYALEERFEESVQLKTAVYQRIGSGD
                     AFISGALYQLLHHSSLKTTIDFAVASATLKCTLPGDHLSTSATSIENLLANAQDIIR"
     gene            complement(17348..17989)
                     /locus_tag="VQ540_000882"
     CDS             complement(17348..17989)
                     /locus_tag="VQ540_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RpiB/LacA/LacB family sugar-phosphate isomerase"
                     /protein_id="HET2544706.1"
                     /translation="MKIALINENSQASKNHIIYDSLKEATDKKDYQLFNYGMRGEEGE
                     SQLTYVQNGLMAAILLNTKAVDFVVTGCGTGVGAMLALNSFPGVVCGLAVDPTDAYLY
                     SQINGGNALSIPYAKGFGWGAELTLKLMFERLFAEEMGGGYPRERVIPEQRNARILNE
                     VKQITHNDLMTILKTIDQDFLKDTISGKYFQEYFFENCQDDEVAAYLKEVLAK"
     gene            complement(18008..18823)
                     /locus_tag="VQ540_000883"
     CDS             complement(18008..18823)
                     /locus_tag="VQ540_000883"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HET2544707.1"
                     /translation="MTNTSFSIEQFSLKGKIALITGASYGIGFAIAKSYAEAGATIVF
                     NDINQDLVNKGIEAYREVGIEAHGYVCDVTDEDGIQAMVKQIEQEVGVIDILVNNAGI
                     IRRVPMCEMSAADFRKVIDIDLNAPFIVSKAVIPSMIKKGHGKIINICSMMSELGRET
                     VSAYAAAKGGLKMLTRNIASEYGGANIQCNGIGPGYIATPQTAPLRELQEDGSRHPFD
                     QFIIAKTPAARWGNPEDLMGPAVFLASDASNFVNGHILYVDGGILAYIGKQPE"
     gene            19094..19522
                     /locus_tag="VQ540_000884"
     CDS             19094..19522
                     /locus_tag="VQ540_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET2544708.1"
                     /translation="MKIVLVGHGHFATGIYSSLQLIAGNQENVEAIDFVEGMSADELK
                     QKILLAISNEEEVLILSDLLGGSPFKVSSTIMGENPVKTMNVLSGLNLAMLMEAVFAR
                     MAHSFDEVVNKSVVAAQGGVVNGKELFSTDAEEEDFESGI"
     gene            19534..20724
                     /locus_tag="VQ540_000885"
     CDS             19534..20724
                     /locus_tag="VQ540_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003074342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HET2544709.1"
                     /translation="MIKKVTIEKIKSPERFLEVPLLTKEEVGQAIDKVIRQLELNLDY
                     FKEDFPTPATFDNVYPIMDNTEWTNGFWTGELWLAYEYSQQDAFKNIAHKNVLSFLDR
                     VNKRVELDHHDLGFLYTPSCMAEYKINGDGEAREATLKAADKLIERYQEKGGFIQAWG
                     DLGKKEHYRLIIDCLLNIQLLFFAYQETGDQKYYDIAESHFYASANNVIRDDASSFHT
                     FYFDPETGQPFKGVTRQGYSDDSCWARGQSWGVYGIPLTYRHLKDESCFDLFKGVTNY
                     FLNRLPKDHVSYWDLIFNDGSAQSRDSSATAIAVCGIHEMLKHLPEVDADKDIYKHAM
                     HAMLRSLIEHYANDQFTPGGTSLLHGVYSWHSGKGVDEGNIWGDYYYLEALIRFYKDW
                     NLYW"
     gene            20735..21226
                     /locus_tag="VQ540_000886"
     CDS             20735..21226
                     /locus_tag="VQ540_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000178618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HET2544710.1"
                     /translation="MTMPNIIMTRIDERLIHGQGQLWVKYLACNTVIVANDEVSTDKM
                     QQTLMKTVVPDSVAMRFFPLQKVIDIIHKANPAQTIFIVVKDVKDALTLVEGGVPIKE
                     INIGNIHNAPGKEQVTRSIFLGEEDKAALKELSQTHQVTFNTKTTPTGNDGAVQVNIM
                     DYI"
     gene            21241..22020
                     /locus_tag="VQ540_000887"
     CDS             21241..22020
                     /locus_tag="VQ540_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HET2544711.1"
                     /translation="MSINVFQAILIGLWTAFCFSGMLLGIYTNRCIVLSFGVGIILGD
                     LPTALAMGAIGELAYMGFGVGAGGTVPPNPIGPGIFGTLMAITSAGKVSPEAALALST
                     PIAVAIQFLQTFAYTVRAGAPETAMKHLKNHNLKKFKFTLNATIWLFAFIGFTLGCLG
                     ALSMDTLLKLVDYIPPVLLTGLTVAGKMLPAIGFAMILSVMAKKELIPFVLLGYVCAA
                     YLNIPTIGIAIVGTIFALIEFYNKPKTANHVVEEEAHDDWI"
     gene            22007..22825
                     /locus_tag="VQ540_000888"
     CDS             22007..22825
                     /locus_tag="VQ540_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HET2544712.1"
                     /translation="MTGSNKLTKRDYLKTSLRAFFCQNGFNYSNYQGLGYANVMYPAL
                     KKHYGEDQEGFYQALEENCEFYNTNPHFLPFITSLHLVMLENGRPAKETRSIKMALMG
                     PLAGIGDSLSQFCLAPLFSTIAASFAQEGLVVGPILFFLAMNTILTAIKLSTGLYGYK
                     LGTTVIDKLSEQMATISRIANIIGVTVIAGLAATSVKIMVPITFAAGEVKADAKQSIV
                     SIQGMLDKVAPALLPALFTLLVYYLIKEKKWTTYKLVILTVVIGIIGSWLKIIA"
     gene            22825..23118
                     /locus_tag="VQ540_000889"
     CDS             22825..23118
                     /locus_tag="VQ540_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000381741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HET2544713.1"
                     /translation="MDTTLFYGIVIVLAVSPLLLSSFHSIRQQKLLRKQTEQRQEYLA
                     SLTSGDEVLLLSGIHGKIISIKDDLVSLQIAKGVVIYVEKESVMGKTKELLFK"
     gene            23140..25041
                     /locus_tag="VQ540_000890"
     CDS             23140..25041
                     /locus_tag="VQ540_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alginate lyase family protein"
                     /protein_id="HET2544714.1"
                     /translation="MKEERRQFFERVDGNQCRDYILSHCSKDYEKVKSSLERLMDNRF
                     MFDSPWDMEPCSKIHQIQPMVWDQVFEDDPEWAYMLNRQEYLLQFMIGYVVEGDKDYI
                     QKCKFFLFDWIEQVREFSPQSLMTRTLDTGIRSFTWLKLLLLLLKFDMLEEKELEKIL
                     VSLEKQIDFMKSYYRAKYTLSNWGILQTIPMLAIYYFFSDKMDLEEAYHFASEELKQQ
                     IETQILGDGSQFEQSILYHVEVYKALLDLCLLLPDLQDSYRELLEKMATYIQMMTGLD
                     GRTLAFGDSDSTETTEILSLSAVVLNKEDLLNGLDVKVDLLSLLFLGREKVKRLQEFE
                     KRAWQPKSMIFEDSGHVCIKDEHRYLFFKNGPLGSAHSHSDENSFCLQYQGQPIFIDA
                     GRYSYREIYERYLLKSAWSHSTCIVDGKAPERITGSWEYEYYPHSLFCHHKEREGVHY
                     IEGAYWSAEPDLPYLHKRKILMLVEDVWLLVDDIRCQGQHEALTQFILDKDVTYQDGK
                     INQLRLWSEVDFDLEDTIISPKYNELERSNKLTKRQFFENQMLDYTIIAHESFEIIRH
                     SVYQTDDREVENALAFEVKNDETDKLILLLSEDICVGEKLCLVDGTKMRGKCLVYDKI
                     NERMIRLQC"
     gene            25101..26102
                     /locus_tag="VQ540_000891"
     CDS             25101..26102
                     /locus_tag="VQ540_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HET2544715.1"
                     /translation="MEKKLTIKDIAEMAQTSKTTVSFYLNGKYEKMSQETREKIEKVI
                     HETNYKPSIVARSLNSKRTKLIGVLIGDITNSFSNQIVKGIEDIASQNGYQVMIGNSN
                     YSQESEDRYIESMLLLGVDGFIIQPTSNFRKYSRIIDEKKKKMVFFDSQLYEHRTSWV
                     KTNNYDAVYDMTQSCIEKGYEHFLLITADTSRLSTRIERASGFVDALTDANMRHASLT
                     IEDKHTNLEQIKEFLQKEIDPDEKTLVFIPNCWALPLVFTVIKELNYNLPQVGLIGFD
                     NTEWTCFSSPSVSTLVQPSFEEGQQATKILIDQIEGRNQEERQQVLDCSVNWKESTF"
     gene            complement(26212..26547)
                     /locus_tag="VQ540_000892"
     CDS             complement(26212..26547)
                     /locus_tag="VQ540_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000838135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2544716.1"
                     /translation="MKSLARLLNIHVFISIFLFFALISGAVSHTVLLLLLLFLPALNK
                     GLEKIQSKRIPVLNAALFFLLISFPQLLTNPVQWKFSIFLVVTIISSLAYFYNFYQVV
                     KEVDQKQLI"
     gene            complement(26558..26800)
                     /locus_tag="VQ540_000893"
     CDS             complement(26558..26800)
                     /locus_tag="VQ540_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2544717.1"
                     /translation="MKKEKKQLRYPGLKAGSIYGTVIFFIIPLIDTLTSENPNFISSL
                     LNTKHIFKTILGAFFFGVMIHIVDSLRIARAKKDQD"
     gene            complement(26811..27353)
                     /locus_tag="VQ540_000894"
     CDS             complement(26811..27353)
                     /locus_tag="VQ540_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3278 domain-containing protein"
                     /protein_id="HET2544718.1"
                     /translation="MKKETFTEKLIKRTYGISGPLDEYKRREADSIGNQVFIVLFYLM
                     IFGNLIPLLLAYKYPQEVALIYPPLILVIALIAAGYVTYQMKKTGITVIEPDMLNEKE
                     SKQLHYPGLKAGLFFGLWMFFITPLLSILIDEGQDYFHSLLTIRNGVSSILGSIFFGA
                     SIQFLISRRIAKTKKNQDED"
     gene            complement(27369..27563)
                     /locus_tag="VQ540_000895"
     CDS             complement(27369..27563)
                     /locus_tag="VQ540_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001082472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET2544719.1"
                     /translation="MNRVKEFRKELGISQLELAKDIGVSRQTINMIENDKYNPTLELC
                     LNLARSLQTDLNSLFWEEDF"
     gene            27729..28679
                     /gene="rsmH"
                     /locus_tag="VQ540_000896"
     CDS             27729..28679
                     /gene="rsmH"
                     /locus_tag="VQ540_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HET2544720.1"
                     /translation="MTKEFHHVTVLLHETIDMLDVKPDGIYVDATLGGAGHSEYLLSK
                     LSEKGHLYAFDQDQNAIDNAQKRLAPYIEKGMVTFIKDNFRHLQARLREAGVQEIDGI
                     CYDLGVSSPQLDQRERGFSYKKDAPLDMRMNQDASLTAYEVVNHYDYHDLVRIFFKYG
                     EDKFSKQIARKIEQAREVKPIETTTELAEIIKLVKPAKELKKKGHPAKQIFQAIRIEV
                     NDELGAADESIQQAMDMLALDGRISVITFHSLEDRLTKQLFKEASTVEVPKGLPFIPD
                     DLKPKMELVSRKPILPSAEELEANNRSHSAKLRVARKIHK"
     gene            28691..29008
                     /gene="ftsL"
                     /locus_tag="VQ540_000897"
     CDS             28691..29008
                     /gene="ftsL"
                     /locus_tag="VQ540_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HET2544721.1"
                     /translation="MAEKMEKTGQILQMQLKRFSRVEKAFYFSIAVTTLIVAISIIFM
                     QTKLLQVQNDLTKINAQIEEKKTELDDAKQEVNELLRAERLKEIANSHDLQLNNENIR
                     IAE"
     gene            29012..31264
                     /gene="pbpX"
                     /locus_tag="VQ540_000898"
     CDS             29012..31264
                     /gene="pbpX"
                     /locus_tag="VQ540_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2X"
                     /protein_id="HET2544722.1"
                     /translation="MKWTKRVIRYATKNRKSPAENRRRVGKSLSLLSVFVFAIFLVNF
                     AVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDE
                     NYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNLKQVSFGAKGNGITY
                     ANMMSIKKELEAAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHENEDGSKSLLGTSG
                     MESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQRTMDGKDVYTTISSPLQSFMETQ
                     MDSFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEGITEDFVWRDILYQSNYE
                     PGSTMKVMMLAAAIDNNTFPGGEVFNSSELKIADATIRDWDVNEGLTGGRMMTFSQGF
                     AHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLPADNIVNIAQSSF
                     GQGISVTQTQMIRAFTAIANDGVMLEPKFISAVYDPNDQTARKSQKEIVGNPVSKDAA
                     SLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIADEKNGGYLVGLT
                     DYIFSAVSMSPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMKDSLNLQTTA
                     KALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVGTGTKIKNSSAEEGKNLAP
                     NQQVLILSDKVEEVPDMYGWTKETAETLAKWLNIELEFQGSGSTVQKQDVRANTAIKD
                     IKKITLTLGD"
     gene            31266..32246
                     /locus_tag="VQ540_000899"
     CDS             31266..32246
                     /locus_tag="VQ540_000899"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000470804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HET2544723.1"
                     /translation="MFISISAGIVTFLLTLVGIPAFIQFYRKAQITGQQMHEDVKQHQ
                     AKAGTPTMGGLVFLITSVLVAFFFALFSSQFSNNMGMILFILVLYGLVGFLDDFLKVF
                     RKINEGLNPKQKLALQLLGGVIFYLFYERGGDMLSVFGYQVHLGIFYIVFALFWLVGF
                     SNAVNLTDGVDGLASISVVISLSAYGVIAYVQGQMDILLVILAMIGGLLSFFIFNHKP
                     AKVFMGDVGSLALGGMLAAISMALHQEWTLLIIGIVYVFETTSVMMQVSYFKLTGGKR
                     IFRMTPVHHHFELGGLSGKGNPWSEWKVDFFFWGVGLLASLLTLAILYLM"
BASE COUNT        10195 a         5314 c         6970 g         9887 t
ORIGIN      
        1 atcgctataa gaaaaaatca ttttattggt ataaagaagt gattgaaagt aatggcgaaa
       61 cgttagataa ttagttcata aaaaacaagt ttagatcctc atctaaactt gtttttttaa
      121 aattgaagga tgattttgga ggatatgaga tgacattgac tattcatgta tattataaag
      181 gcgatggaga ttgtgcaata aagtttgcaa gagaaatgct tgaatctggg cttgtcgcag
      241 aaattagatg tcaaaaaggt aatttgaaat acgaatattt tttaccaatt gaaaaagagg
      301 gaattattct ccttattgat cagtggataa atcaagaagc tttagatgaa catcatcaat
      361 caaatacaat gcagaaaatc ttagatttaa gaaaaaaata tcacttgcag atgcaagttg
      421 aacgttatat agaagatgat tctgggatgc cagaaagcga taagtcgttt atagacacag
      481 ggaattagaa ttattgtgag agtttttgta gtttgaaagt attgaaaatc gtaaagatat
      541 cattacgaga atacaagaag atattgttct atttccatta aaaattactt ctttccttaa
      601 taataaggaa aaagaatacg ttttcatctt ttggtttgag gtttataata agaatatcaa
      661 agtcaggagg aaaaaagatg actactttta aagatggatt tttatggggt ggtgctgttg
      721 ctgctcatca acttgaaggc ggatggcaag aaggtggcaa aggaattagt gttgctgatg
      781 ttatgactgc tggtcgccat ggagtagctc gtgaaattac tttgggagtt ttagagggta
      841 aatattatcc aaatcatgag gcgatagatt tttatcatcg ttataaagaa gacatagcac
      901 tttttgctga aatgggattc aagtgcttcc gtacctctat tgcatggaca cgtatctttc
      961 caaaaggtga tgagttagag ccgaatgaag aaggattaca gttttatgat aatctttttg
     1021 atgaatgctt aaagaatggt attgaacctg tcatcactct atctcatttt gaaatgcctt
     1081 atcacttagt gaccgaatat ggtggttgga aaaataggaa attgattgat ttctttgctc
     1141 gttttgcaga agtcgtattt aaacgttaca aagataaggt taaatattgg atgactttca
     1201 atgaaatcaa taatcaagcg aattatcagg aagattttgc accatttact aactcaggta
     1261 ttgtatatga ggaaggtgat aatagagaag caattatgta tcaagcagca cattacgaat
     1321 tagttgcttc tgcacgagct gtaaaaattg gtcatgagat taatccagat tttcaaatag
     1381 gttgtatgat tgcgatgtgt ccaatttatc cagttacttg caatcctaag gatatcttaa
     1441 tggcaatgaa agctatgcag aagcgttatt attttgctga tgtgcatgtt ttaggtaaat
     1501 atcctgagca tattttcaag tattgggaac gaaaaggtat ttcagttgat tttactgacc
     1561 aggataaaga agatttactt ggtgggactg tagattacat tggtttcagt tactatatgt
     1621 cctttgctat agactctcat cgtgaaaata atccttattt tgattatctt gaaacagaag
     1681 atttagtgaa aaataattat gttaaggctt ctgaatggga gtggcaaatt gatccagaag
     1741 gtttacgtta tgcgttaaat tggtttacag accactatca cttaccactc tttattgttg
     1801 aaaatggttt tggagctata gatcaagttg cagcagatgg tatggtacat gatgattata
     1861 gaattgaata tctaggtgcc catattcgtg aaatgaaaaa ggctgtagtt gaagatggtg
     1921 ttgatttaat gggttatact ccatggggat gtattgattt ggtttcagct ggtaccggtg
     1981 aaatgcggaa acgttatggc tttatttatg tagataaaga tgacaatggg aagggaagtt
     2041 ataatcgttc cccgaaaaaa tcttttggct ggtataagaa agttatttta tctaacggtg
     2101 aatcagtaga atagtataaa caaactgaga ttattctcag tttgtttagc atattgagga
     2161 gacatatgat tggaagtatt gcagcaattt taacaacatt tgcattttta ccacaagttt
     2221 ttcgtgtagt taagacaaag gacacaggat ctattgctct aggtatgtat gttatgcaag
     2281 ttattggtat tgcattgtgg cttgctcatg gtattcgtat aggagacttg cctttgattt
     2341 tagcaaatag tgtttcattt ctactctcag gaataatttt attttataaa ttgaagtata
     2401 aataattttt ttccatatca tttaggaaaa tgagggaatt gtcattgaaa acgctttatt
     2461 ttataataaa aatagataac aaataagcca acttagcaca gctttgattg gatttaagaa
     2521 aaggagaaaa tattatggca aaagctttaa ttatttgtgc agcaggaatg tcttcatcac
     2581 ttatggcaca gaaaacaaca gagtttctaa aaggaaaagg gaaagatatt gtagttgatg
     2641 ctattagtgc tactgaagga gggaaagcta tcgcagcagc agcttttgat ttgtatcttg
     2701 tcagtcctca aacaaaaatg tactttaagc aatttgaaga ggctggttct aaagcaggaa
     2761 aaccagttgt acaaatacct cctcaagcct atattcctat tccaatggga attgaaaaaa
     2821 tggctaattt gattcttgag aatatttgat gaacacatga aatgtcaata aatatttaag
     2881 ttaagataaa ttgttttgag tttgatataa attgatttaa gtgtataata tgcttcaata
     2941 tatgaaaaca tacgttttag gagggaatga atgtgttaaa cattaaagag aaagatatcc
     3001 ttcaattttt aataaaaaat aaggaacgtt ttgttacaag caaagaactg gcagaatatt
     3061 tatcctgttc agatagaact gtccgtaatg tactgaaatt aattgagaag acaatgatta
     3121 ttcaaggagt ccggttgatt tcaaaacaag gtcaagggta tcaaatattt tttgagaatc
     3181 aaggcgctta ccaggagttt agacaaactt atgaactgga agaagactat acgaaaactg
     3241 cggtttcaaa aggtgatgat cgtttagtat ttatcttaaa taaattatta tttgagcaag
     3301 ttccagttct ttttgatgat ttagctgatg aactttacgt tagtcgttca acattatctc
     3361 atgatttcag aaagatacga gtgatgttat cagagtataa tttgtccatt gagagtaggg
     3421 cgaataaagg agtttatgtc tcaggcgagg aacgtgataa acgacgtttt atcataaatt
     3481 atttcctaga gaatcaattt tttaaaacaa tacattgcta tgtaaaattt aacttttttg
     3541 ctcaaactgt tccattagaa gaatttgcta gaattgtttt ggatgaatgc caagaggcca
     3601 acctaaaact atctgatttt gtactacaga atttagtagt tcacatagca ttgtctgtga
     3661 ttcgtttaaa atccggattt gaaataaaaa atatagactg tcagatgact gatgatgcaa
     3721 tagagagaaa ggttgctcaa agaattcttt ctaaagtaag agaagtaaca aatcaggaat
     3781 ttccagttca ggaaatagac tacattactt tgcatttgtt agctaagagt caacaatgtc
     3841 aaaaaaatca gaagaatatt tctgaagaag ttttaaaaaa atctttattt aaaacatttc
     3901 agaatttagg attagatgat atgtataact tttcttcaga tttccaacta attgaaggat
     3961 tgataactca tctaatgaca ctacaagtac gtttagaaag ccggattacc ttaaataacc
     4021 ctttggtaga tgaaattaaa cagaattata gtgatatatt ctttatgact agagaaattc
     4081 ttgcaaatat ggacaagttc ttggagtgga caatatcaga tgatgaagta gcatatgtaa
     4141 gtcttcactt tttagctgct atggaacgta gcaaagagag tactaagttt aatattcttg
     4201 ctatttgtgc aacaggattt ggtgcagccc aaatgttaag aaatcgtttg gaaacggagt
     4261 ttgggaagcg agtagaagtt gttgatgtaa taggctatta tgaattgaat caagaaaaac
     4321 ttaaaggaat agattttata gtgtcagctg ttgatttatc aaatctatat tttcaaattc
     4381 cagtttttaa agttagtgtg tttcttaaga gtgatgagat ggaaatgatt agaaaagcta
     4441 tggatcagat gcaagtttct agttatgtac aatcatcaaa gattaataaa tttgaaaaca
     4501 acagctttag acagtatttt agtaaagaaa attttttaat atgtactgaa tcagacaagg
     4561 taaatttact tgaaaagatg gttgagagtt tatctgttgg tgaatcaaat gagtttgaac
     4621 aatctttact ttatggaatt aaacagcgcg aagaattaag ttcagttgtt ttttctgaaa
     4681 aaattgcagt tccgcatcct attcagccct ttggtacaga gggaaaggtt tcggttgcaa
     4741 tctgtaaaga ttcgttactc tgggataatc aaagttcata tgtccagcta gtatttcttc
     4801 tatctccatc aatatatggg aacgaaggtt tggcaactgt gactaaaaag atagtctctc
     4861 tgacagagaa tgatgagttg caaaatcagc taatatcttg caataacttt gaagatttta
     4921 ttagcatatt tgagaagata aaataggagg ttcatatgaa tcaagaggaa ctgcaggttg
     4981 cagcatttga aattatcctg cattcgggaa atgcaaggtc agaaatacat gaagcatttg
     5041 caaaaatgag agaaggtagt tttgatgatg cagaaagtaa attaaatcaa tcaaatgaga
     5101 taattcttga agcgcatcat gcacaaacca aactcttgca agaatacgca agtggagtgg
     5161 aaattaaaat tgaaattatc atggtacatg ctcaagatca tttaatgacc actatgacat
     5221 tattagaagt agcaaaggaa atgttagctc tttataagaa agttaactaa atatgtgttg
     5281 ttatataagg aggaaatgat atggataaaa aagaacgaca aaagattgaa caacaacgtc
     5341 gagagatggc tctaactaat acttttttta atcgatatct tcttctacgt tattcaatag
     5401 cactcttctt ttttgggaat atttattggc ttttgaatca gtttattaat ccctcgccta
     5461 ttattatttt ccccattatg ctcatagtat tttctatttt agcaactgtt gaacaattta
     5521 aactctatgg aaataggaaa gaaaagttgg gaataacact aatgtttgtt agaatacaaa
     5581 tacttatttc aataggatta cttgttttaa cttggacaag ttggtttaag aatctttttc
     5641 cgatttttga aaataaccaa gtagcacgtt tatttgtttt tgtagttctt ctattaggtt
     5701 tagttctgag tttgttagac attagaagaa ttaaaaaaat ttataaacga acagataagg
     5761 cttatcaaca atttgtccaa ttggaaaaga actcacttag tttataatcc tgatctagta
     5821 taatttgtat ttgaaactag tctttagaaa gtaaaaatta ttatgtttta ttaaggaggt
     5881 ctatttatgg atcaacaaaa cgggttgttt ggttttcttg aaaaccatgt tatgggacca
     5941 atgggcaaac ttgctcagtt taaagtagtg cgtgctatca cggctgcagg tatggctgct
     6001 gtaccattta ctattgtagg atcaatgttt ttggtattca gtattttgcc acaagctttc
     6061 tcattttggc caattgtggc agatattttc tctgcttcat ttgataaatt cacatcactt
     6121 tacatggttg caaactatgc gactatgggt tctctatctc tttatttcgt tctatcactt
     6181 gcatatgaat tgacaaaaat ttatgcagag gaagaagaac tcaatatgaa tcctcttaat
     6241 ggtgccttgc tcgccttgat ggcttttgtc atgacagtac cgcaaatcat ttttgatggt
     6301 ggaatgatga agactgtgac aagtctaaaa gaaggtgcag taattgcaga tggatgggca
     6361 atgggaaatg gagtcgcacg ttttgggaca acagggattt ttaccgcaat cattatggca
     6421 attgtgactg ttcttattta tcgtatgtgt gttaaacata attgggttat taaaatgcct
     6481 gaagctgttc cagaaggagt ttctcgtgga tttaccgctt tggttccggg atttgttgtt
     6541 gcatttgttg ttatctttat caacggtctt cttgtagcaa tgggaacaga tatttttaaa
     6601 gtcattgcaa ttccatttgg ttttgtatcc aatctgacta attcgtggat tggtttaatg
     6661 attatttatc tattgactca actactttgg attgtaggta tccacggtgc gaacattgtt
     6721 tttgcatttg ttagtccaat tgctcttgct aacatggctg aaaatgctgc tggcgggcac
     6781 ttcgctgttg caggtgaatt ttctaatatg tttgtaattg caggtggttc tggtgcaact
     6841 ttaggactat gtttatatat tgcttttgcc tctaaatctg aacagcttaa agcaatagga
     6901 cgagcatctg tagttccagc cttatttaat attaatgaac cattaatttt tggattacct
     6961 attatctata atccagcctt ggctatacca tttattttag caccaatggt tactgctact
     7021 atttattacg tagcgaattc tctaaacttt attaagccaa ttatcgcaca ggttccatgg
     7081 ccaactccag tagggattgg agctttctta gggacagcag atcttcgagc tgtattagtt
     7141 gctctagtat gtgcatttgc agcattctta gtctatcttc cattcatccg tgtatatgat
     7201 caaaaattgg tgaaagaaga gcaaggtatc taataagtaa aaaagtatac tcgatgatag
     7261 aatccatata gtttaaataa tgagtgttaa tattagcagt gaagaggtct ttttaagata
     7321 ttcttctctg ctttttcata ttttttcgct atgtagggta tgaagcaaaa tagaaagtag
     7381 ttcgaatagt tgataaacag gaaactgctg ttatttaaaa aaaacaataa agtaaagtat
     7441 gttatcgtag aatacgatac aatagtaaaa aagcaaaaag aatgcgtttt atatttgggt
     7501 ttgaggttta taaaatagga taagcgtgct gaaaacttag atatgacaaa caaaataaaa
     7561 tttttaaaag ctacatagaa acatggtata atgtatctaa aggaggtagc atatgtcctt
     7621 agatatagat aaagaaaaga tgacaatcat gggaatagct tttgaaaaca gatccgtttt
     7681 taagagtgtt tggtatgctt taagtacaaa tatgattgaa ggatggcgac ctacggttag
     7741 tgatgttgaa aaattacgag atgaagctct tgctctgggg atgacttaat gaagcgcaac
     7801 tgttatgagt cttatgacta tgttgatccg gataatttat ataccgatcc gggttcttca
     7861 gttctaagaa ataagcagga aggaaaaaag cacgcgagct tgaatatcgt atgattgcta
     7921 gtaagagttt gaaattattt atcaatccta tcttagttaa tagtttaaaa gtagtttgtt
     7981 tcacaactgc ataagcttag aaaagttgaa aagtgataac tctttaataa actcttggtt
     8041 tgttaaaaga tattttgtcc actacatttt ttcaattgac tattatttgt catagatata
     8101 acagatagaa cagatagaac attgcattca gaataatgaa aaacgcatca aaaatggtgc
     8161 gttctgtttt tatgctacca taaaaggagg aaaacaaatt gaaaattttt aagggagagt
     8221 tttatcgaat ctctgtatta acagacaagc tagtaaggtt agaatactct caaactggaa
     8281 gttttgagga tagaacgaca caacttatct ataatagaga ttttggccaa gtttcgttag
     8341 attatatcga gacatcaaac gtactagata ttatgacgga ctattttcat ctgcacttta
     8401 ataaaggaga atttaacgcc gaaaatttat ttatagaatt aaaaggaaat tttgccgtat
     8461 atggtagtcg ctggtatttt ggtgaatcta ttgaaacgtt aaaaggaaca gctcggactc
     8521 tggataaggc agatggagca atctcgttag aagatggaat tattagccga aatggtatag
     8581 ccttattgga tgattctcaa ggatttattt gggatgaaca atctggttat attgagagag
     8641 aaaatcaaat tgacctgtat ttctttgcct atgggcatga ttatagagga gcaatcagag
     8701 acttttacca tttgactggt tcaacaccct tgttgccaag atatgcttta ggcaattggt
     8761 ggagtagata ttggccttat acgtcggatg aatacttgga tttaatagac agatttgaaa
     8821 cagagaaaat tccattatct atcggtgtgt tagatatgga ttggcatata actgacattc
     8881 cagctcgttt tggaagtggc tggacaggat atagttggaa tagaaactta ataccaaatc
     8941 cagaacagtt attgcaacaa cttcatgata gaaagttaaa actctcctta aatgtccatc
     9001 ctgctgatgg gatacgggct tatgaagaag cttatcctca aatcgcaaaa cggttggggt
     9061 taaatgtaga actagaagaa cctgctattt ttgatttttt taatccctct tttagggaag
     9121 cctactttaa agatgttcat tatgagctag aaaagcaggg agtagatttt tggtggattg
     9181 actggcaaca agggacacaa ggtatgctag atccactttg gcttttaaac cattatcact
     9241 atcaggatag ttgtaaaaat gcagaaggtg gtttgatttt atcaagatat gcaggtcctg
     9301 gtagtcaccg ctaccctgtt ggtttttcag gggatactat tattagttgg aattccttaa
     9361 ggtttcaacc ctattttaca gcgacagcat ctaatatcgg ttatagttgg tggagtcatg
     9421 atatcggtgg acatatgttg ggggattatg acgaagagct acaaactaga tggctacagt
     9481 ttggtgtttt tagtccgatt actcgattac atagttctag aagtcctttt aatagtaaag
     9541 aaccttggtt cttttcagaa acaacatcta agattatgaa gaaatacctt cgtttgagac
     9601 atcagatgat tccctatcta tataccatga atgtaaagac acatgaggaa ggtgccccat
     9661 taatcagtcc aatctattat ttctatccag agaatgatga gagctataat gttccaaacc
     9721 aatacttttt tggaacagaa ctgatggtgg ctcccattgt agaaaagatg gatttgacat
     9781 tccaatctgc aaaagtagat gtatggttcc ctgaaggtga atggtatgac ttcttttcag
     9841 agaaaaaata cacaggtggt gtgaagttaa gtgtttatag ggacatctcg actacgcctg
     9901 tgtttgcaaa aagtggtgca atcattccct tggttggttc tgagataggt atgggtgttg
     9961 atttacctga ggttgtagat tggtatgtat tcccagggaa acaacatttt tttgaaatgc
    10021 ttgaagatca aaatggtcaa agatataaaa caagattatc aatcgattgg gaaatgggaa
    10081 tggtagagtt agcattacaa ggagattcta gtatcgttcc aagcaataga aaacatagaa
    10141 ttcattttaa aggaacgaat gtgtctataa ttgaattgcc aaataagaat gatacagcta
    10201 aatttgaatg gaaagataat aaaaggacat ctttaaatga cgaagttttt agactactaa
    10261 agacagcttc tcttccatat gaattaaaag atagattgtt aaatcaattc atcaatgcga
    10321 aaaactctca tgacttaatg aatatcttgc atcatcagga taaggaattg agagggcgtt
    10381 tgttggaaat gatatttact agccaaaact aattgaaata attagaaagt catttgttta
    10441 gtgtatatga agattctgta tggtattcgt tatcactggt cacattgaaa atgtgaaata
    10501 agcacctaca acatagactt tacaacactt catgtttcat atcatggggt gtttttctat
    10561 ttaagtcaaa gcccatcaaa aaatctcact attcatcagg ttaaaggaaa cctaatcata
    10621 gtgagattgt gaattatagt agagtttgta tcgcctcttc aatttgtttt gggtctgttt
    10681 ttgaagaaaa gcgttcaaag acttgcccat ctcgaccgat gagaaactta gcgaaattcc
    10741 attcgattcg ttttcctagt gggccggatt tctggtcttt taaccagaca tagagagggt
    10801 ctgcttcctt accgttgacc ttaatcttgg caaaacgtgg gaaggtggtt tgaaaatgta
    10861 ggctacagaa ggcgttgatt tcctctgcgc tgccgggtgc ttgtcccata aactgattgc
    10921 aagggaaatc caatatttcg aagccctgat cttgatagcg ttcatagagt tcttgaagtc
    10981 cctggtactg gggcgttaaa ccacatccag tagcagtgtt gacaatcaag agaactttgc
    11041 cacgatagct atccaaggga gttgcttggt tgttttggtt caaaacggaa aaatcataaa
    11101 gtgaagtcat gagggcctct tttctttttc tacattgtaa cagtttttac ttttttcgtc
    11161 gagtcggatg gaagatattg ttgaagaata agccttcaat atgatagaaa ccgtttacaa
    11221 ataactttaa aaatggtatg atttaattaa accggtttac ttagttgcta taaatctcta
    11281 atttgagatt tagttcctat tgattttaca atatgtttat tggagtgtat acatgcaaac
    11341 aaaaacaaag aagctcattg tgagtttgtc ttcacttgtt ttatcaggat ttttattaaa
    11401 ccattatatg acagttggag cggaagaaac gactacgaat accattcagc aaagccagaa
    11461 ggaagttcag tatcagcaaa gggatacaaa aaatttagtt gaaaatggtg attttggtca
    11521 gacggaggac ggaagcagtc cgtggacagg aagcaaagct caggggtggt cagcttgggt
    11581 agaccagaag aatagtgcag atgcctcaac tcgagtcatt gaggctaagg atggggctat
    11641 cactatctca agccatgaga aattaagggc agcggttcac cgtatggttc ctattgaagc
    11701 taagaaaaag tataaactgc gtttcaagat taaaacagat cataaagtcg ggattgccaa
    11761 agttcgtatc attgaggaaa gtgataagga caagcgattg tggaattctg caacgacgtc
    11821 aggaacaaag gactggcaga ccattgaagc agactatagc ccgactttag atgttgataa
    11881 aatcaagctg gagttattct atgaaacagg aactgggact gtttccttta aggatattga
    11941 gctggtagag gtagcagacc agccttctga ggactatcaa acagataaac agcttgagga
    12001 aaagattgat ttaccaattg gaaaaaaaca tgttttttct cttgcggact atacttataa
    12061 ggtagaaaat cctgacgttg cttcagtcaa aaatggaatt ttagaacctc ttaaggaagg
    12121 gacaaccaat gtcattgtca gtaaagatgg caaggaagtg aaaaagattc ctttgaagat
    12181 tctagcctct gttaaggatg catacacaga ccgtttggat gactggaatg gcatcatcgc
    12241 tgggaatcaa tactatgatt ctaaaaatga acagatggcc aaattaaacc aggaattgga
    12301 aggaaaggta gctgatagcc tatctagtat ttcaagtcag gcggaccgca cctatttgtg
    12361 ggaaaaattt tcaaattata aaatgtctgc aaatctgact gccacttatc ggaaattgga
    12421 ggagatggcc aagcaagtga ccaatccttc ttctcgttat tatcaagatg aaactgtcgt
    12481 tcgaacagtc agggattcca tggaatggat gcataaacat gtctacaata gtgaaaagag
    12541 cattgttggg aactggtggg attatgaaat cggtacacct cgtgccatca acaatacctt
    12601 gtctctgatg aaagaatact tctctgatga ggaaattaaa aaatatacag atgtgattga
    12661 aaaatttgta ccagatcccg aacatttccg aaagacgact gataacccat ttaaggctct
    12721 aggtggaaac ttagttgata tgggaagagt aaaagtaata gctggtttac tgcgtaagga
    12781 tgatcaagaa atttcttcta ccattcgctc gattgagcaa gtgttcaagt tggtagacca
    12841 aggtgaaggt ttttatcaag atggatccta tatcgaccat accaatgttg cctatacggg
    12901 tgcttatggg aatgttttga ttgatggcct gtctcaactg ttgccagtca ttcaaaagac
    12961 caagaatcca atcgataaag ataaaatgca aaccatgtac cactggattg ataaatcgtt
    13021 tgctcctttg ctggtgaatg gagagctgat ggatatgagt cgtggacgct cgatcagtcg
    13081 tgcaaatagc gaggggcacg tggccgcagt agaagtacta agagggattc accgaatagc
    13141 ggatatgtct gaaggagaaa ccaaacaacg tttgcagagt cttgtgaaga ccattgttca
    13201 atcggatagt tattatgatg tctttaagaa tttgaagact tataaggata tcagtttgat
    13261 gcaatccttg ttaagtgatg caggagtcgc aagtgttcca agaacaagtt acctatctgc
    13321 ctttaacaag atggataaaa cagccatgta caatgcagag aaagggtttg gatttggctt
    13381 gtcactcttt tccagtcgta ccttgaatta cgaacacatg aacaaggaaa ataaacgtgg
    13441 ttggtatacg agtgatggga tgttctatct ttacaatggc gatttgagtc actatagcga
    13501 tggctactgg ccaacagtta atccatataa gatgcctggt acaacagaga cggatgctaa
    13561 gagagcggat agcgatacag gtaaagtttt accgtctgct ttcgttggaa cgagcaaact
    13621 agatgatgcc aatgcgacag caaccatgga tttcaccaac tggaatcaaa cattgactgc
    13681 tcataagagc tggtttatgc taaaggataa gatcgccttt ttaggaagca atatccaaaa
    13741 cacttcaaca gatactgctg caactacaat tgaccagaga aaactggaat caagtaatcc
    13801 atataaagtc tatgtcaatg ataaagaagc ctcccttaca gaacaagaaa aggattatcc
    13861 tgaaacccaa agtgtctttt tagaatcatc cgattcgaaa aagaatattg gttacttttt
    13921 ctttaagaag agttcaatca gtatgagtaa ggctttgcaa aagggagcct ggaaggatat
    13981 caatgaagga cagtcagaca aggaagttga aaatgaattt cttacgatta gtcaggctca
    14041 taagcaaaat ggagattctt atggctatat gctcatccct aacgtgggtc gtgccacctt
    14101 caatcaaatg ataaaagagt tagaaagaag cctcatcgaa aataacgaaa cccttcagtc
    14161 tgtttatgat gccaaacaag gagtttgggg cattgtgaaa tatgatgatt ctgtctctac
    14221 tatttccaac caattccaag ttttgaaacg tggagtctat accattcgaa aagaagggga
    14281 tgaatataag attgcctact ataatcctga aacccaggaa tcagctccag atcaggaagt
    14341 ctttaaaaag ctagagcaag cagctcagcc acaagtacag aattcaaaag aaaaggaaaa
    14401 atctgaagag gaaaagaacc attcggatca aaagaatctc cctcagacag gagaaggtca
    14461 gtcaatcttg gcaagtctag ggttcttgct acttggggcg ttttatttat tccgtagagg
    14521 aaagaacaac taatttgttc atcatctaga tgaattacat gaaactgtgg aaaatagaaa
    14581 aaatccgaag aaggccaaat atcttcggat ttttctttta aaaaaggata agttgatact
    14641 tatccttttt acttcattat gtgactatag cgttttgaaa ctagaatagg acatcataac
    14701 tgctaaaaga tttctataaa ttcatttgat tttcctaatc aatttattcg tatcctattt
    14761 cactctacta tattagtccg tctcgcacct cacggagcga gacaaaacaa ccacccgcta
    14821 tgcgggtgcg cgtcgaaggt tataccaaaa aaactccaaa cgcgatacaa taaaggtgtt
    14881 caatccactt gtaaagcgaa aggagaaaaa atatggcaca aaaggctcat agtttatctc
    14941 acacaaagtg gaggtgttct atcacattgt gttcacccct aagtatagac gaaaagtcat
    15001 ctataatcaa tatagaagta gtttaggcga aatatttcat cgcttgtgta gttataaagg
    15061 tgttgaaatg atcgagggtc acttaatgcc agaccatgta cacatgttag tcagtattcc
    15121 actaaggcta agtgtttcga gtttcatggg ttatttaaaa ggaaaaagtg cactcatgat
    15181 gtttgacaaa cacgccaatc tcaagtacaa gtttgggaat cggcatttct gggtggaagg
    15241 ttattatgta agtccagtag ggcttaatga agccacaatt aagaaatata gtcaagatta
    15301 aagaaattat ccagtggatg atttcttcac gagtatgaaa atttgagaac tagtaaagta
    15361 tgatatatag taaaatgaaa taagaacagg acaaaatcga tcaggacagt caaatcgatt
    15421 tttaacaatg ttttagaagt agaggtatac tattccagtt tcaatctact atagcactag
    15481 ataaattgag tgtaaaagaa tatgaggatc cctttaggga tagtggtaag taataccaaa
    15541 gtctcttaaa gaggcaagtg acgagtcaag agcaataagg cttgaacaac gtaaaagcca
    15601 gcgtctttag gcgctggctg atgatttggg cttatagctc tgggataaac cacccgttag
    15661 acgggtagtt atgattttat ctgagtgtaa tatactgttg ggcaatctcg ctgatgcggt
    15721 caaagttgcc ttgggaagcg agtttattga gttcgccacc aattccaacg gcatctgcac
    15781 cagcagcgaa ccattgaggg atgttgttta ggccgactcc tccggttacc attacggaaa
    15841 cttgtgggat cggtgccttg actgcagaga tatatgctgg actgagagta ctacctggga
    15901 agagtttgat gatttcacta ccggcttcaa gtgcagtcgt gatctctgtg agggtaatac
    15961 agcctggaat gtacggtgtg ctgtagagat tgcacatttt cgcagtttca gcatggaaag
    16021 atggagaaac aacgtaattt gctccagcta gaatggcatc tctagcagtt acggcatcaa
    16081 gcacagtacc tgcaccgata caaacactct gatcgtcctg atacaagtct acaagttcct
    16141 tgatgatttg tcctgcatac tgattggtat aggcgatttc aatagctttg ataccgccct
    16201 tgatacaagc aatcgaggct tgtagtcctt cttcctttgt atttcctcga atgacagcga
    16261 caattttctg tttttttagt tcaataatcg tatctgattt ggtcatgtaa ttctcctaac
    16321 gaatgatatc ttgtgcattt gccagtaaat tttcaatact agttgcggaa gtggagagat
    16381 ggtctcctgg aagagtgcat ttgagagttg cgctcgcaac tgcaaagtca atggtagttt
    16441 ttagggagga atgatggagt agttggtaaa gggcaccaga tataaaggca tccccgctac
    16501 caattcgttg atagactgca gtttttagtt ggacagactc ttcaaatcgt tcttccagag
    16561 cataggcttg atagacattt ttgtcttgct catcactaga tcggagggta tggaaaatgg
    16621 ccttgaaacc ataggcttct tttaaaagtc gcatgcgatt ttccacctct tctaggctag
    16681 cactgtctct tggaaacatc tctagatttt ggtcatcaat catgagagga tcaataccga
    16741 agcaatagtc agtaaaacgt gcaaacttag aaaattcata cttggcttct aggactgaaa
    16801 tcatctttgt tctcagattg agatccattg aaacgacaat tcctcggcgc ttggcttctt
    16861 ccaagagtag gagaaggatc gcacggacct cttgaccgat agctatggtg attccactaa
    16921 aatgaaaatg gctaatcccc tgaaagagag aatccatatc tagcatgttt ggccgaatct
    16981 ggctgatact cgtatgctta cgatcgtaga aaacttcact ttgacgacaa ccaaagccgt
    17041 tctccaaata gtagaggccg attcgatcgc caagccgaca gattgaactg gtatcgattt
    17101 ggtgctgttt caagaatgtg agaaaacgat ctccaatctc gttggcaggg agtgcggtaa
    17161 agactttcgt tgagataccc agggcttgca aattacaagc gatgttaatt tctgatccgc
    17221 caaaataagt cgaactggca acatgatcgc cgatactggt ggcatctaat ggtgagattc
    17281 gaattaatgg ttcgccaaac agtaatattt tcgtcatcca ttagttcctt tctggtttag
    17341 aatagcttta cttggctaat acttctttca aataagcagc gacttcatca tcttggcagt
    17401 tttcaaagaa gtattcttgg aagtatttgc cagagatggt gtctttgagg aagtcttggt
    17461 cgattgtttt aaggatggtc atcaaatcat tgtgggtgat ttgtttcacc tcgtttaaga
    17521 tacgagcgtt gcgttgttca gggattacac gttctcttgg gtagccaccg cccatttctt
    17581 cagcaaataa gcgttcaaac atcaatttga gggtcagttc tgccccccag ccaaatcctt
    17641 tggcataagg gatagacaag gcgttaccac cattgatttg agaataaagg taagcgtcag
    17701 ttgggtccac tgctagacca cagacaacac cagggaagct gtttaaagca agcatagccc
    17761 ctacacccgt accacagccg gtaacaacaa agtcaactgc ctttgtattt aaaaggatgg
    17821 cagccattag tccgttctgc acataagtta attgactttc tccttcttct ccacgcatac
    17881 catagttaaa taattggtag tcttttttat ctgtcgcttc ttttagacta tcgtaaataa
    17941 tgtgattctt gctagcttga ctattttcat tgattaatgc gattttcata agatcttctt
    18001 tctattttta ctcaggttgt tttccgatgt aggctaagat accgccatct acatatagga
    18061 tgtggccatt gacaaaattg ctggcatcac tagcgagaaa gacagcaggg cccatcaaat
    18121 cttcaggatt tccccaacgt gcagcaggtg tttttgcaat gatgaactgg tcaaatgggt
    18181 ggcgagaacc atcttcttgc aactcacgaa gaggtgctgt ttgaggagtg gcaatataac
    18241 ccggtccaat tccgttacat tggatattgg ctccaccgta ttcagacgca atgttgcggg
    18301 tcaacatttt caagccccct ttagcagcag cataagcgct aactgtttca cgtcccagtt
    18361 cgctcatcat cgaacaaata ttgataatct ttccatgccc tttctttatc atagaaggaa
    18421 taactgcctt tgaaacgata aatggtgcgt ttaagtcaat atcgatgacc ttacggaaat
    18481 cagcggcgct catttcgcac attggaactc ggcggataat accagcgtta ttaacgagga
    18541 tgtcaatgac accaacctct tgttcgattt gcttgaccat ggcttggata ccgtcctcgt
    18601 ctgtcacgtc acagacatat ccatgggctt cgatgccaac ttcacgataa gcttcaatcc
    18661 ctttattgac cagatcttga ttgatatcgt taaagacaat agtagcgccg gcttcagcgt
    18721 aggatttggc aatagcaaat ccaattccat aagaagcgcc ggtgatgaga gcaatttttc
    18781 cttttaaaga aaactgctca attgagaatg atgtatttgt catttgatac ttcctttcaa
    18841 atttgttaag acttctctat aaccaaatta tattctagca aaccggtttt gtcaataaat
    18901 aaatattttt atttataaaa agatttgttt tcctgaaaaa cggaatgttt tgaaatttct
    18961 gtttattaaa atggttaaaa agataatgaa agcgctaata tttttttaaa aaaactattg
    19021 acaagataaa aataaaggat tacaatgggg aatataaagt aaaccggtaa acctaaacaa
    19081 gaaaggagaa aagatgaaaa ttgtacttgt agggcatgga cattttgcta cagggattta
    19141 tagttcttta caattgattg caggtaatca agaaaatgtg gaggcgattg actttgtgga
    19201 aggaatgtca gcagatgaac tcaagcaaaa aatcttactt gcaatttcaa atgaagaaga
    19261 agttttaatc ctaagtgatc tcttgggagg atcgccattc aaggtttctt ctaccataat
    19321 gggagaaaat ccagtcaaaa caatgaatgt tctctcgggt ttgaacttag ccatgttaat
    19381 ggaagcagtc tttgctagaa tggctcatag ctttgatgag gttgttaata aatcagtagt
    19441 ggcggcccag ggcggagtcg taaatggtaa agaattgttt tcaacggatg cagaggaaga
    19501 agatttcgaa tcgggtattt aaagggtaaa agaatgataa aaaaggttac gattgaaaaa
    19561 ataaaatcgc ctgagcgctt cttagaagta ccacttctga cgaaagaaga agtcggccag
    19621 gcaatcgata aggttattcg gcagttagaa ctcaaccttg actatttcaa ggaagatttc
    19681 ccgacgccag ctacctttga taatgtctat ccaatcatgg ataacacgga atggaccaat
    19741 ggtttctgga caggagaact gtggttggct tatgaataca gtcaacagga tgcatttaaa
    19801 aacatcgctc ataaaaatgt tctttctttc ctggatcgtg tcaataagag agtagaattg
    19861 gatcaccatg atctcggctt cttgtacaca ccgtcttgta tggctgaata taagataaat
    19921 ggagatggag aggctagaga agcaaccttg aaagctgcag ataagttgat tgaacgctat
    19981 caagaaaaag gtggttttat tcaagcttgg ggagacttgg gcaagaaaga gcattaccgt
    20041 ttgattatcg actgcttgct caatatccaa ctcttattct ttgcttatca agaaacaggc
    20101 gatcaaaaat actacgatat tgcagaaagt catttctatg cttcagctaa taatgtaatc
    20161 cgtgatgacg cttcgtcctt ccacaccttc tattttgatc ctgagacagg tcaacccttt
    20221 aaaggtgtaa cgagacaagg gtatagtgat gattcatgct gggcacgtgg tcaatcatgg
    20281 ggagtctatg gtattccttt gacttatcgt cacttaaaag acgagtcctg ctttgacttg
    20341 tttaagggtg tgaccaatta tttcttgaat cgtctgccaa aagatcatgt gtcctattgg
    20401 gatttgattt ttaatgatgg tagtgctcaa tcacgagatt cttcagcaac agctatcgcc
    20461 gtctgtggga ttcatgaaat gctaaaacat ctcccagagg tggatgctga caaagatatt
    20521 tataaacatg ctatgcatgc catgcttcgt tccttgatcg aacattatgc aaatgatcaa
    20581 tttacccctg gtgggacaag tcttctccac ggtgtgtact catggcattc aggtaaagga
    20641 gtggatgaag gcaatatctg gggtgactac tattacctag aagcccttat ccgtttctac
    20701 aaagactgga acctatattg gtaggaggag aaatatgaca atgccaaata ttattatgac
    20761 ccgtatcgat gaacggttga ttcatggaca aggacaactt tgggtaaaat acctagcttg
    20821 taatacggtc attgttgcca atgacgaagt aagcacggac aagatgcaac aaactctgat
    20881 gaaaacagtt gtgccagact cagttgccat gcgtttcttc cctttgcaaa aggtgattga
    20941 tatcattcac aaggctaatc ctgctcaaac gatctttatc gttgtaaagg atgtaaagga
    21001 cgctttaacc ttggtagaag gtggtgtccc tatcaaagaa atcaatattg ggaacattca
    21061 caatgcccct ggtaaagagc aagtgacacg ctccatcttc ctgggtgaag aggacaaggc
    21121 agccctcaag gaattaagcc aaactcatca agtaacattt aatacgaaaa caactccaac
    21181 aggaaatgat ggagctgttc aagtcaacat tatggactat atttaaaaga ggagatcgtt
    21241 atgtcgatta atgtatttca agcgatttta attggattat ggacagcttt ctgttttagt
    21301 ggaatgctgt taggaattta caccaataga tgtattgttc tgtcatttgg tgtcggaatt
    21361 attctaggtg atctgcctac tgctcttgca atgggagcta ttggtgaatt ggcttatatg
    21421 ggattcggtg ttggtgctgg aggtactgtt ccaccaaacc caatcggacc tggtatcttt
    21481 ggtaccttga tggctatcac tagtgctggt aaagtcagtc cagaagcggc tcttgccctc
    21541 tctactccga ttgctgtggc gattcaattc ttacaaactt tcgcctacac tgtacgtgct
    21601 ggtgcgcctg aaacggcgat gaagcacttg aaaaaccata atttgaagaa attcaagttt
    21661 actctaaatg caacaatttg gttgtttgcc tttattggat ttaccttggg ttgcttgggt
    21721 gccctttcaa tggatacctt gttgaaactc gtagactaca ttccaccggt attacttaca
    21781 ggtttgacag ttgctggtaa aatgctccca gctatcggtt ttgcgatgat cttgtcagtg
    21841 atggctaaga aagagttgat tccctttgtc ttgttgggat atgtttgtgc agcttatcta
    21901 aacatcccaa caattggtat tgcaattgta ggtactatct ttgctttgat tgaattttat
    21961 aacaagccaa aaacagcgaa tcatgtggta gaggaggaag cacacgatga ctggatctaa
    22021 caaattaaca aaacgtgatt atcttaaaac gtctttgcgg gcattctttt gtcaaaatgg
    22081 atttaactat agtaactatc aagggttggg atatgccaat gtgatgtatc ctgctttgaa
    22141 aaaacactat ggagaggatc aggaaggttt ctaccaagcc ttggaagaaa actgtgaatt
    22201 ctataatacc aacccacact tcctgccttt tattaccagc ttgcatcttg taatgttgga
    22261 aaatggccgt ccggcaaaag aaacacgtag catcaagatg gccttgatgg gaccattggc
    22321 aggtattggg gattctcttt ctcaattctg tttagctcca ttgttctcaa ccatcgcagc
    22381 ttcgtttgct caagaaggct tggttgtcgg tccaatcttg ttcttccttg cgatgaatac
    22441 gattttaaca gcgattaaat tgtcaactgg tctgtatgga tacaaactag gaacaactgt
    22501 gattgataaa ctaagcgaac agatggcaac gatttctcgt attgccaata ttatcggtgt
    22561 aaccgtaatt gctggtttgg cagcgacatc tgttaagatt atggtgccga ttacctttgc
    22621 tgcaggggaa gttaaagcag acgctaaaca aagtatcgta agtattcagg gaatgcttga
    22681 taaggttgct ccagctcttc taccagccct atttacactt ttagtttact acttgatcaa
    22741 agaaaagaaa tggacaacat ataaactcgt tattttaaca gttgtcatcg gaattatcgg
    22801 aagctggctt aagattatag cttaatggat acaacattgt tttatggaat agtgattgtc
    22861 ttggcagtga gtcccctttt actgtcaagc tttcattcta ttcgtcagca aaagttgctt
    22921 cgcaaacaga cggagcaacg acaagagtat ttagcttctt taacatctgg tgatgaagtg
    22981 ttgttattgt ctggaattca tggaaaaatc atttctatca aagatgactt ggtctccttg
    23041 cagattgcaa aaggtgtggt catctatgta gaaaaggaaa gtgtaatggg aaagacaaaa
    23101 gaactgcttt ttaagtagtt ctttttctgg taatagataa tgaaagaaga aagaagacaa
    23161 ttttttgaaa gagtcgatgg aaaccaatgt cgtgattata tcttgtcgca ctgttcaaaa
    23221 gactatgaga aagtcaagag ttcccttgaa cgcttgatgg acaatcgttt tatgtttgat
    23281 agtccttggg atatggagcc ttgttcaaaa atccatcaaa tccagccgat ggtatgggat
    23341 caagtatttg aagatgatcc agaatgggct tatatgctca atcgacaaga atatctcttg
    23401 cagtttatga tagggtatgt ggtagaagga gataaggact atattcaaaa gtgcaagttc
    23461 tttctatttg attggattga gcaggtgaga gaattttctc ctcaatcctt gatgactaga
    23521 accttggata cgggtattcg ttcctttact tggttgaaac tactcttgct cctcttgaaa
    23581 tttgacatgc tagaggagaa agaactagag aaaattttgg tcagtctaga aaagcagatt
    23641 gactttatga aaagctacta tcgcgccaag tacaccctta gtaactgggg gattttacaa
    23701 acaattccga tgcttgctat ctattatttc ttttcagata agatggacct agaagaagct
    23761 taccattttg cttcagagga gttgaaacag caaattgaga cacagatttt aggagatgga
    23821 agccagtttg aacagtcgat tctctatcat gtagaggttt ataaagcctt gctggatttg
    23881 tgtctcttgc ttccagactt gcaagatagt taccgagagt tgctggaaaa gatggcgacc
    23941 tatattcaaa tgatgacagg cttagatgga cgaactttgg cttttggtga tagcgattct
    24001 acagaaacga cagaaatttt gagcctgtct gctgtggttt tgaacaagga agaccttctt
    24061 aacggtctgg atgttaaagt cgatttgctt agcctcttgt tcctggggcg agaaaaggtc
    24121 aagcgactgc aggaatttga aaagagagct tggcagccta agtccatgat ctttgaagac
    24181 tctggacatg tctgcattaa ggatgaacat cgttatctat ttttcaaaaa tggtccgcta
    24241 ggaagtgccc atagccatag tgacgagaat agtttttgct tacagtatca aggacaacct
    24301 attttcatag atgctgggcg ttattcttat cgggagatat atgaacgtta tctcttaaag
    24361 agtgcttgga gtcattcgac ctgcattgta gatgggaaag ctccggaaag aatcacggga
    24421 tcctgggaat atgaatacta tcctcactcc ctgttttgtc accataaaga aagggaggga
    24481 gtgcattata ttgaaggggc ttattggtca gcagaacctg atttgcctta tcttcacaag
    24541 agaaaaatcc tcatgttggt agaggatgtc tggctcttgg tggatgacat caggtgtcaa
    24601 ggtcagcatg aggcgttgac tcagtttatc cttgacaagg atgtgaccta tcaagatggg
    24661 aaaatcaatc agttgagact atggagtgaa gttgattttg atttggaaga taccatcatt
    24721 tctcctaaat acaatgagct tgaaagaagt aacaaactca ccaagcgcca attctttgag
    24781 aatcagatgc tggattatac catcattgcg catgagagtt ttgaaatcat ccgtcattct
    24841 gtctaccaga cagatgatcg tgaagtggaa aatgctctgg cttttgaagt gaaaaatgac
    24901 gaaacagaca agctgattct gttattaagc gaggatattt gtgtaggtga aaaattgtgc
    24961 ctcgttgacg gaacaaaaat gcgtggaaaa tgtctagtat atgataaaat aaatgagaga
    25021 atgattcgct tgcagtgcta gaaataggca ttttgaatag tgaatatgtt ataataagta
    25081 ttagtaggag gtgttttaga ttggagaaga aactgaccat aaaagacatt gcggaaatgg
    25141 ctcagacctc gaaaacaacc gtgtcatttt acctaaacgg gaaatatgaa aaaatgtccc
    25201 aagagacacg tgaaaagatt gaaaaagtta ttcatgaaac aaattacaaa ccgagcattg
    25261 ttgcgcgtag cttaaactcc aaacgaacaa aattaatcgg tgttttgatc ggtgatatta
    25321 ccaacagttt ctcaaaccaa attgttaagg gaattgagga tatcgccagc cagaatggct
    25381 accaggtaat gataggaaat agtaattaca gccaagagag tgaggaccgg tatattgaaa
    25441 gcatgcttct cttgggagta gacggcttta ttattcagcc gacctctaat ttccgaaaat
    25501 attctcgtat catcgatgag aaaaagaaga aaatggtctt ttttgatagt cagctctatg
    25561 aacaccggac tagctgggtt aaaaccaata actatgatgc cgtttatgac atgacccagt
    25621 cctgtatcga aaaaggttat gagcattttc tcttgattac agcggatacg agtcgtttga
    25681 gtactcggat tgagcgggca agtggttttg tggatgcttt aacagatgct aatatgcgtc
    25741 acgccagtct aaccattgaa gataagcata cgaatttgga acaaattaag gaatttttac
    25801 aaaaagaaat cgatcccgat gaaaaaactc tggtatttat ccctaactgt tgggccctac
    25861 ctctagtctt taccgttatc aaagagttga attataactt gccacaagtt gggttgattg
    25921 gttttgacaa tacggagtgg acttgctttt cttctccaag tgtttcgacg ctggttcagc
    25981 cctcctttga ggaaggacaa caggctacaa agattttgat tgatcagatt gaaggccgta
    26041 atcaagaaga aaggcaacaa gtcttggatt gtagtgtgaa ttggaaagag tcgactttct
    26101 aaaatgaagg aaaatgactt gcaatctctg ttaagaaata aaataatccc acctagaaca
    26161 agctaggtgg gattatttgc ttatgaaatg agaaattatg ggagcaagct cctaaatcaa
    26221 ctgtttttga tctacttctt taactacttg ataaaagtta tagaagtagg ccaaacttga
    26281 aatgatggtt acgactagga atattgaaaa tttccattgg acagggttgg ttaaaagttg
    26341 tggaaaggat atgaggagaa agaagagggc tgcgttgagg acaggtatcc gttttgattg
    26401 tattttctca agtcctttat tgagcgcagg aagaaagagg agtaggagta gtaaaactgt
    26461 atgagaaaca gctcctgaaa taagggcgaa gaaaaggaaa atactgataa aaacatgaat
    26521 gttcagtagt ctagctagtg atttcataag gcacctccta atcctggtct tttttagctc
    26581 ttgcaatacg aagtgagtcg acaatatgta tcatcactcc gaaaaagaaa gctcccagta
    26641 tagttttaaa aatatgtttt gtatttagaa gagaactgat aaaatttgga ttttcacttg
    26701 ttagggtatc aatgagtgga attataaaaa atatcactgt tccataaatc gaacctgctt
    26761 tcagaccagg ataacgtaac tgtttctttt cttttttcat gagtttcctc ctaatcctca
    26821 tcttgatttt tcttagtttt tgcaatgcga cgggagatga ggaactgtat gctcgctccg
    26881 aagaaaatag aaccgagaat acttgataca ccatttctta tagtgagaag agaatgaaaa
    26941 tagtcctgac cttcatctat gagtatactg agaagaggag ttataaaaaa catccataga
    27001 ccaaagaaca aacctgcttt cagacctggg tagtgtagtt gcttgctttc tttctcattc
    27061 agcatatctg gttcaatgac tgtgatgcct gtttttttca tttggtaggt gacatagcca
    27121 gcagcgatga gggcaatcac taaaatcaga ggaggataga ttagagccac ttcttgaggg
    27181 tatttatagg ctagaaggag tggaataaga tttccgaaaa tcatcagata aaagaggacg
    27241 ataaagactt ggttcccaat actatcggcc tcacgccgtt tgtattcgtc aaggggacca
    27301 gaaataccgt atgtgcgttt gatcagtttt tcagtgaagg tttctttttt catgagtttg
    27361 ctcctttttt aaaaatcttc ctcccaaaag agactgttga ggtcagtttg gaggctgcgg
    27421 gcgagattga gacagagttc caaggttgga ttgtacttgt cgttttcaat catattgata
    27481 gtctgtctcg agacaccgat atccttggcg agttcgagct gggaaatacc caattccttg
    27541 cgaaattctt tcacacgatt catctggtct cctttctgat ttatgtcgta tatatttgac
    27601 tatattatag tcttttaaac ataaagtgtc aagtatattt gacatatttt ttgaagaaat
    27661 agtagtctcc ttgtcctatt tgtctgacaa gtgcaagctg gtcggatttg tggtaaaata
    27721 gataagatat gacaaaagaa tttcatcatg taacggtctt actccacgaa acgattgata
    27781 tgcttgacgt aaaacctgac ggtatctacg ttgatgcgac tttgggtgga gcaggccata
    27841 gcgagtattt attaagtaaa ttaagtgaaa aaggccatct ctatgccttt gaccaggatc
    27901 agaatgccat tgacaatgcg caaaaacgct tggcacctta cattgagaag ggaatggtga
    27961 cctttatcaa ggataacttc cgtcatttac aggcacgttt gcgcgaagct ggtgttcagg
    28021 aaattgatgg aatttgttat gacttgggag tgtctagtcc tcaattggac cagcgtgagc
    28081 gtggtttttc ttataaaaag gatgcgccac tggacatgcg gatgaatcag gatgctagtc
    28141 tgacagccta tgaagtggtt aatcactatg actatcatga tttggttcgt attttcttca
    28201 aatacggtga ggataaattc tctaaacaga ttgcgcgtaa gattgagcaa gcgcgtgaag
    28261 tgaagccgat tgagacaacg actgagttag cagagattat caagttggtc aaacctgcca
    28321 aggaactcaa gaagaagggt catcctgcta agcagatttt ccaggctatt cgaattgaag
    28381 tcaatgatga actgggagcg gcagatgagt ccatccagca ggctatggat atgttggctc
    28441 tggatggtag aatttcagtg attacctttc attccttaga agaccgcttg accaagcaat
    28501 tgttcaagga agcttcaaca gttgaagttc caaaaggctt gcctttcatc ccagatgatc
    28561 tcaagcccaa gatggaattg gtgtcccgta agccaatctt gccaagtgcg gaagagttag
    28621 aagccaataa ccgctcgcac tcagccaagt tgcgcgtggc cagaaaaatt cacaagtaag
    28681 agggaaaaag atggcagaaa aaatggaaaa aacaggtcaa atactacaga tgcaacttaa
    28741 acggttttcg cgtgtggaaa aagcttttta cttttccatt gctgtaacca ctcttattgt
    28801 agccattagt attattttta tgcagaccaa gctcttgcaa gtgcagaatg atttgacaaa
    28861 aatcaatgcg cagatagagg aaaagaagac cgaattggac gatgccaagc aagaggtcaa
    28921 tgaactatta cgtgcagaac gtttgaaaga aattgccaat tcacacgatt tgcaattaaa
    28981 caatgaaaat attagaatag cggagtaaga tatgaagtgg acaaaaagag taatccgtta
    29041 tgcgaccaaa aatcggaaat cgccggctga aaacagacgc agagttggaa aaagtctgag
    29101 tttattatct gtctttgttt ttgccatttt tttagtcaat tttgcggtca ttattgggac
    29161 aggcactcgc tttggaacag atttagcgaa ggaagctaag aaggttcatc aaaccacccg
    29221 tacagttcct gccaaacgtg ggactattta tgaccgaaat ggagtcccga ttgctgagga
    29281 tgcaacctcc tataatgtct atgcggtcat tgatgagaac tataagtcag caacgggtaa
    29341 gattctttac gtagaaaaaa cacaatttaa caaggttgca gaggtctttc ataagtatct
    29401 ggacatggaa gaatcctatg taagagagca actctcgcaa cctaatctca agcaagtttc
    29461 ctttggagca aagggaaatg ggattaccta tgccaatatg atgtctatca aaaaagaatt
    29521 ggaagctgca gaggtcaagg ggattgattt tacaaccagt cccaatcgta gttacccaaa
    29581 cggacaattt gcttctagtt ttatcggcct agctcagctc catgaaaatg aagatggaag
    29641 caagagcttg ctgggaacct ctggaatgga gagttccttg aacagtattc ttgcagggac
    29701 agacggcatt attacctatg aaaaggatcg tctgggtaat attgtacccg gaacagaaca
    29761 agtttcccaa cgaacgatgg acggtaagga tgtttataca accatttcca gccccctcca
    29821 gtcctttatg gaaacccaga tggattcttt tcaagagaag gtaaaaggaa agtacatgac
    29881 agcgactttg gtcagtgcta aaacagggga aattctggca acaacgcaac gaccgacctt
    29941 tgatgcagat acaaaagaag gcattacaga ggactttgtt tggcgtgata tcctttacca
    30001 aagtaactat gagccaggtt ccactatgaa agtgatgatg ttggctgctg ctattgataa
    30061 taataccttt ccaggaggag aagtctttaa tagtagtgag ttaaaaattg cagatgccac
    30121 gattcgagat tgggacgtta atgaaggatt gactggtggc agaatgatga ctttttctca
    30181 aggttttgca cactcaagta acgttgggat gaccctcctt gagcaaaaga tgggagatgc
    30241 tacctggctt gattatctta atcgttttaa gtttggagtt ccgacccgtt tcggtttgac
    30301 ggatgagtat gctggtcagc ttcctgcgga taatattgtc aacattgcgc aaagctcatt
    30361 tggacaaggg atttcagtga cccagacgca aatgattcgt gcctttacag ctattgctaa
    30421 tgacggtgtc atgctggagc ctaaatttat tagtgccgtt tatgatccaa atgatcaaac
    30481 tgctcggaaa tctcaaaaag aaattgtggg aaatcctgtt tctaaagatg cagctagtct
    30541 aactcggact aacatggttt tggtagggac ggatccggtt tatggaacca tgtataacca
    30601 cagcacaggc aagccaactg taactgttcc tgggcaaaat gtagccctca agtctggtac
    30661 ggctcagatt gctgacgaga aaaatggtgg ttatctagtc gggttaaccg actatatttt
    30721 ctcggctgta tcgatgagtc cggctgaaaa tcctgatttt atcttgtatg tgacggtcca
    30781 acaacctgaa cattattcag gtattcagtt gggagaattt gccaatccta tcttggagcg
    30841 ggcttcagct atgaaagact ctctcaatct tcaaacaaca gctaaagctt tggagcaagt
    30901 aagtcaacaa agtccttatc ctatgcctag tgtcaaggat atttcacctg gtgatttagc
    30961 agaagaattg cgtcgcaatc ttgtacaacc catcgttgtg ggaacaggaa cgaagattaa
    31021 aaacagttct gctgaagaag ggaagaatct tgccccgaat cagcaagtcc ttatcttatc
    31081 tgataaagta gaggaagttc cagatatgta tggttggaca aaggagactg ctgagaccct
    31141 tgctaagtgg ctcaatatag aacttgaatt tcaaggttcg ggctctactg tgcagaagca
    31201 agatgttcgt gctaacacag ctatcaagga cattaaaaaa attacattaa ctttaggaga
    31261 ctaatatgtt tatttccatc agtgctggaa ttgtgacatt tttactaact ttagtaggaa
    31321 ttccggcctt tatccaattt tatagaaagg cgcaaattac aggccagcag atgcatgagg
    31381 atgtcaaaca gcatcaggca aaagctggga ctcctacaat gggaggtttg gttttcttga
    31441 ttacttctgt tttggttgct ttctttttcg ccctatttag tagccaattc agcaataata
    31501 tgggaatgat tttgttcatc ttggtcttgt atggcttggt cggattttta gatgactttc
    31561 tcaaggtctt tcgtaaaatc aatgaggggc ttaatcctaa gcaaaaatta gctcttcagc
    31621 ttctaggtgg agttatcttc tatcttttct atgagcgcgg tggcgatatg ctttctgtct
    31681 ttggttatca agtgcatcta gggattttct atattgtctt cgctcttttc tggctagtcg
    31741 gtttttcaaa cgcagtaaac ttgacagacg gtgttgacgg tttagctagt atttccgttg
    31801 tgattagttt gtctgcctat ggagttattg cctatgtgca aggtcagatg gatattcttc
    31861 tagtgattct tgccatgatt ggtggtttgc tcagtttttt catctttaac cataagcctg
    31921 ctaaggtctt tatgggtgat gtgggaagtt tggccctagg tgggatgctg gcagctatct
    31981 ctatggctct ccaccaagaa tggactctct tgattatcgg aattgtatat gtttttgaaa
    32041 caacttctgt tatgatgcaa gtcagttatt tcaaactgac aggtggtaaa cgtattttcc
    32101 gtatgacgcc tgtacatcac cattttgagc ttgggggatt gtctggtaaa ggaaatcctt
    32161 ggagcgagtg gaaggttgac ttcttctttt ggggagttgg gcttctagca agtctcctga
    32221 cccttgcaat tttgtatttg atgtaagaat ggcaccctga tgtttcaggg tgtttttgtg
    32281 tttaaataca caatgaaaat caaagaacaa actagaaagc taactttagg ctgctcaaaa
    32341 tatagtagat tgaaactaga atagta
//
LOCUS       DAVBDR010000019        31002 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.019, whole genome shotgun sequence.
ACCESSION   DAVBDR010000019 DAVBDR010000000
VERSION     DAVBDR010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 31002)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31002)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31002
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.019"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            complement(298..516)
                     /locus_tag="VQ540_000900"
     CDS             complement(298..516)
                     /locus_tag="VQ540_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001207345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET2544724.1"
                     /translation="MVLNYKPLWIQLAKKGLKKTDVIAMAGLTTNVMAQMGKDKPITF
                     KNLERICKALSCTPNDIISFEDNFSDEE"
     gene            complement(762..1040)
                     /locus_tag="VQ540_000901"
     CDS             complement(762..1040)
                     /locus_tag="VQ540_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2544725.1"
                     /translation="MKKDKEVYDKVCEYLSPHLNKDMEMLELACWFRVIIVIEANSYV
                     NIRSSRLLPKFKTQKINSWCAAYSIHFNNGYCKQHTNEFKDSLKSLIL"
     gene            complement(1254..2885)
                     /gene="rlmD"
                     /locus_tag="VQ540_000902"
     CDS             complement(1254..2885)
                     /gene="rlmD"
                     /locus_tag="VQ540_000902"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000914584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HET2544726.1"
                     /translation="MLKKNDIVEVEIVDLTHEGAGVAKVDGLVFFVENALPSEKILMR
                     VLKVNKKIGFGKVEKYLVQSLHRNQDLDLAYLRSGIADLGHLSYPEQLKFKTKQVKDS
                     LYKIAGIADVEVAETLGMEHPVKYRNKAQVPVRRVNGVLETGFFRKNSHNLMPLEDFF
                     IQDPVIDQVVVALRDLLRRFDLKPYDEKEQSGLIRNLVVRRGHYSGQIMVVLVTTRPK
                     VFRVDQLIEQVIKQFPEIVSVMQNINDQNTNAIFGKEWCTLYGQDYITDQMLGNDFQI
                     AGPAFYQVNTEMAEKLYQTAIDFAELKKDDVVIDAYSGIGTIGLSVAKHVKEVYGVEL
                     IPEAVENSQKNASLNKITNAHYVCDTAENAMKKWLKEGIQPTVILVDPPRKGLTESFI
                     KASAQTGADRIAYISCNVATMARDIKLYQELGYELKKVQPVDLFPQTHHVETVALLSK
                     LDVDKHISVEIELDEMDLTSAESKATYAQIKEYVWNKFELKVSTLYIAQIKKKCGIEL
                     REHYNKSKKDKQIIPQCTPEKEEAIMDALRHFKMI"
     gene            complement(2959..3933)
                     /locus_tag="VQ540_000903"
     CDS             complement(2959..3933)
                     /locus_tag="VQ540_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1002 domain-containing protein"
                     /protein_id="HET2544727.1"
                     /translation="MRKKLFLTSAAVLWAVTAMNSVHAATDVQKVIDETYVQPEYVLG
                     SSLSEDQKNQTLKKLGYNASTDTKELKTMTPDVYSKIMNVANDSSLQLYSSAKIQKLG
                     DKSPLEVKIETPENITKVTQDMYRNAAVTLGMEHAKITVAAPIPVTGESALAGIYYSL
                     EANGAKVPQANKDLAQEELKALSDINAENKDKSGYDANKLNVALADIKSGLAKAKESK
                     GNLTEEDVRKIVEDTLKNYKLDQVITGNQINIIINFALNLSKSDILSNADFTKTLNDL
                     KQSIVSQAGDSFKNINLNFDADKALEDGGNFLSSLWQALVNFFKSFGS"
     gene            complement(4007..4621)
                     /gene="pmp23"
                     /locus_tag="VQ540_000904"
     CDS             complement(4007..4621)
                     /gene="pmp23"
                     /locus_tag="VQ540_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000476388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall hydrolase Pmp23"
                     /protein_id="HET2544728.1"
                     /translation="MFKRIRRVLVLAVFLFAGYKAYRVHQDVKQVMTYQPMVREILSE
                     KDTPANEELVLAMIYTETKGKEGDVMQSSESASGSTNTINDNASSIRQGIQTLTGNLY
                     LAQKKGVDIWTAVQAYNFGPAYIDFIAQNGKENTLALAKQYSRETVAPLLGNTTGKTY
                     SYIHPISIFHGAELYVNGGNYYYSRQVRLNLYIIKCFTLFSTSG"
     gene            complement(4621..5595)
                     /locus_tag="VQ540_000905"
     CDS             complement(4621..5595)
                     /locus_tag="VQ540_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HET2544729.1"
                     /translation="MDIYIKKAIIHQFSPDDTELFLADKFLNITPKIEEYLRKKIEHV
                     YSDEAKTGIFEEENPFFNHITDDLLETSVTLANLWKEEFSISENLKTNDLIFVQFSKE
                     GVEHFAFLRIALRETLTHLGGEVDNPIKLTQNNLPGFGTGADEALVVNLQSRKYHLIE
                     KRIKYNGTFLNYFSDNLLAVAPKISPKKSIKELEKTAQRIAESFNTDDFQFQSKVKSA
                     IFNNLEESNELSPEKLANDLFDNNLTARLSFIDQVKEAVPEPVQFDEIDASRQLKKFE
                     NQKLSLSNGIELIVPNNVYQDAESVEFIQKENGTYSILIKNIEDIQSK"
     gene            complement(5603..6859)
                     /locus_tag="VQ540_000906"
     CDS             complement(5603..6859)
                     /locus_tag="VQ540_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HET2544730.1"
                     /translation="MIFDKDDFKAYDADLWNAIAKEEERQQNNIELIASENVVSKAVM
                     AAQGSILTNKYAEGYPGRRYYGGTDVVDVVETLAIERAKEIFGAKFANVQPHSGSQAN
                     CAAYMSLIEPGDTVMGMDLASGGHLTHGAPVSFSGQTYNFVSYSVDPETELLDFDAIL
                     KQAQEVKPKLIVAGASAYSQIIDFSKFREIADAVGAKLMVDMAHIAGLVAAGLHPSPV
                     PYAHITTTTTHKTLRGPRGGLILTNDEELAKKINSAIFPGIQGGPLEHVVAAKAVSFK
                     EVLDPAFKEYAANVIKNSKAMADVFLQDPDFRIISGGTENHLFLVDVTKVVENGKVAQ
                     NLLDEVNITLNKNSIPYETLSPFKTSGIRIGAAAITARGFGEEESRKVAELIIKTLKN
                     SENEAVLEEVRSAVKELTDAFPLYEE"
     gene            complement(6921..7352)
                     /locus_tag="VQ540_000907"
     CDS             complement(6921..7352)
                     /locus_tag="VQ540_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000942930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2544731.1"
                     /translation="MLRDLQETDVKAICDINQEALGYTFSPEETASQLARLSQDSHHF
                     LLGYEDAANHVLLGYVHAEVYESLYSKAGFNILALAVSPQAQGQGIGKSLLQGLEQEA
                     KRCGYGFIRLNSANHRLGAHAFYEKVGYTCDKMQKRFIRIF"
     gene            complement(7354..7956)
                     /locus_tag="VQ540_000908"
     CDS             complement(7354..7956)
                     /locus_tag="VQ540_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HET2544732.1"
                     /translation="MMDRIRQELENGGAVVLPTETVYGLFAKALDEKAVDHVYQLKRR
                     PRDKALNLNIASFEDILHFSKNQPTYLQKLVETFLPGPLTIILEANDRVPYWVNSDLA
                     TIGFRMPSHPITLDLIRETGPLIGPSANISGQASGVTFEQILKDFDQEVLGLEDDAFL
                     TGQDSTIVDLSGDKVKILRQGAIKREDILARLPEISFEEA"
     gene            complement(7940..8779)
                     /gene="prmC"
                     /locus_tag="VQ540_000909"
     CDS             complement(7940..8779)
                     /gene="prmC"
                     /locus_tag="VQ540_000909"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000761890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HET2544733.1"
                     /translation="MKLAQLFSNFEEELIRQGEEAESLSFVYRSLKNLSFTDFIFALQ
                     QEVTTEEEKQFVEDIYQQLAAHKPAQYIIGQADFYGMHLKVDERVLIPRPETEELVEL
                     ILTENLETNLSVLDIGTGSGAIALALAKNRPDWSVTAADVSQEALELASENASDQNLN
                     IFFKKSDCFAEISEKYDIIVSNPPYISREDESEVGLNVLHSEPHLALFADEDGLAIYC
                     RIAEDAKDYLKDGGKIYLEIGYKQGQSVPELFRKHLPEKKVRTLKDQFGQNRMVVVDD
                     GQD"
     gene            complement(8779..9858)
                     /gene="prfA"
                     /locus_tag="VQ540_000910"
     CDS             complement(8779..9858)
                     /gene="prfA"
                     /locus_tag="VQ540_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HET2544734.1"
                     /translation="MNIYDQLQAVEDRYEELGELLSDPDVVSDTKRFMELSKEEASNR
                     DTVIAYREYKQVLQNIVDAEEMIKESGGDADLEEMAKQELKDAKAEKEEYEEKLKILL
                     LPKDPNDDKNIILEIRGAAGGDEAALFAGDLLTMYQKYAEAQGWRFEVMEASMNGVGG
                     FKEVVAMVSGQSVYSKLKYESGAHRVQRVPVTESQGRVHTSTATVLVMPEVEEVEYDI
                     DPKDLRVDIYHASGAGGQNVNKVATAVRIVHLPTNIKVEMQEERTQQKNREKAMKIIR
                     ARVADHFAQIAQDEQDAERKSTIGTGDRSERIRTYNFPQNRVTDHRIGLTLQKLDTIL
                     SGKLDEVVDALVLYDQTQKLEELNK"
     gene            complement(9855..10445)
                     /locus_tag="VQ540_000911"
     CDS             complement(9855..10445)
                     /locus_tag="VQ540_000911"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000068157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HET2544735.1"
                     /translation="MAQLYYRYGTMNSGKTIEILKVAYNYEEQGKGVVIMTSALDTRD
                     GVGYVSSRIGMKRPALAIEETTDIFGYIRGLPEKPYCVLVDEAQFLKRHHVYDLARVV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLLADKIDEIKTICQYCKKKATMVLRTQDGL
                     PVYDGEQIQIGGNETYISVCRKHYFAPEINKENEEK"
     gene            10568..10750
                     /locus_tag="VQ540_000912"
     CDS             10568..10750
                     /locus_tag="VQ540_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005589823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HET2544736.1"
                     /translation="MPFVRIDLFEGRTLEQKKALAKEVTEAVVRNTGAPQSAVHVIIN
                     DMPEGTYFPQGEMRTK"
     gene            10887..12260
                     /gene="mnmE"
                     /locus_tag="VQ540_000913"
     CDS             10887..12260
                     /gene="mnmE"
                     /locus_tag="VQ540_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002906470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HET2544737.1"
                     /translation="MITREFDTIAAISTPLGEGAIGIVRLSGTDSFAIAQKIFKGKDL
                     NKVASHTLNYGHIIDPLTGKVMDEVMVGAMKSPKTFTREDIIEINTHGGIAVTNEILQ
                     LAIREGARLAEPGEFTKRAFLNGRVDLTQAEAVMDIIRAKTDKAMNIAVKQLDGSLSD
                     LINNIRQEILNTLAQVEVNIDYPEYDDVEEATTAVVREKTMEFEQLLTKLLRTARRGK
                     ILREGISTAIIGRPNVGKSSLLNNLLREDKAIVTDIAGTTRDVIEEYVNINGVPLKLI
                     DTAGIRETDDIVEQIGVERSKKALKEANLVLLVLNASEPLTAQDRQLLEISQDTNRII
                     LLNKTDLPETIETSKLPEDVIRISVLKNQNIDKIEERINNLFFENAGLIEQDATYLSN
                     ARHISLIEKAVESLQAVNQGLELGMPVDLLQVDLTRTWEILGEITGDAAPDELITQLF
                     SQFCLGK"
     gene            complement(12307..13242)
                     /gene="dapA"
                     /locus_tag="VQ540_000914"
     CDS             complement(12307..13242)
                     /gene="dapA"
                     /locus_tag="VQ540_000914"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HET2544738.1"
                     /translation="MSYQDLKECKIITAFITPFHEDGSINFDAIPALIEHLLAHHTDG
                     ILLAGTTAESPTLTHDEELELFAAVQKVVNGRVPLIAGVGTNDTRDSIEFVKEVAEFG
                     GFAAGLAIVPYYNKPSQEGMYQHFKTIADASDLPIIIYNIPGRVVVELTPETMLRLAD
                     HPNIIGVKECTSLANMAYLIEHKPEEFLIYTGEDGDAFHAMNLGADGVISVASHTNGD
                     EMHEMFTAIAESDMKKAAAIQRKFIPKVNALFSYPSPAPVKAILNYMGFEAGPTRLPL
                     VPAPEEDAKRIIKVVVDGDYEATKATVTGVLRPDY"
     gene            complement(13298..14374)
                     /locus_tag="VQ540_000915"
     CDS             complement(13298..14374)
                     /locus_tag="VQ540_000915"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000542485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HET2544739.1"
                     /translation="MGYTVAVVGATGAVGAQMIKMLEESTLPIDKIRYLASARSAGKS
                     LKFKDQDITIEETTETAFEGVDIALFSAGSSTSAKYAPYAVKAGVVVVDNTSYFRQNP
                     DVPLVVPEVNAHALDAHNGIIACPNCSTIQMMVALEPVRQKWGLDRIIVSTYQAVSGA
                     GMGAILETQRELREVLNDGVKPCDLHAEILPSGGDKKHYPIAFNALPQIDVFTDNDYT
                     YEEMKMTKETKKIMEDDSIAVSATCVRIPVLSAHSESVYIETKEVAPIEEVKAAIAAF
                     PGAVLEDDVAHQIYPQAINAVGSRDTFVGRIRKDLDAEKGIHMWVVSDNLLKGAAWNS
                     VQIAETLHERGLVRPTAELKFELK"
     gene            complement(14716..14788)
                     /locus_tag="VQ540_000916"
     tRNA            complement(14716..14788)
                     /locus_tag="VQ540_000916"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(14753..14755),aa:Thr,seq:ggt)
     gene            complement(14888..15397)
                     /locus_tag="VQ540_000917"
     CDS             complement(14888..15397)
                     /locus_tag="VQ540_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HET2544740.1"
                     /translation="MKKLTIRDIADIAIVAAIYVVLTVTPPLNAISYGAYQFRISEMM
                     NFMAFYNPKYIIGVTIGCMIANFFSFGLLDVFVGGGSTLVFLSLGVWLFAKYSKDYLF
                     NGLIRKDHFFFSILFSISMFTIAAELNIVAELPFFLTWFTTGIGEFASLIIGAIIIGK
                     IGRRIDLSK"
     regulatory      complement(15395..15491)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01054"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class II; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF01054"
     gene            15520..15951
                     /locus_tag="VQ540_000918"
     CDS             15520..15951
                     /locus_tag="VQ540_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HET2544741.1"
                     /translation="MKIPIQKFFNNEILAYLFFGLATTLVSILSRLVIYQLSHQELLA
                     TALANIIGILFAFITNDTIVFKQKKKNRLIRLVKFSLARLSTFLLDLFLTFLFVTQFP
                     HIIGQFVTENIDKINAIETIIAQIFIIIINYILSKAYIFRK"
     gene            16033..16410
                     /gene="mscL"
                     /locus_tag="VQ540_000919"
     CDS             16033..16410
                     /gene="mscL"
                     /locus_tag="VQ540_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HET2544742.1"
                     /translation="MLKNLKSFLLRGNVIDLAVGVVIASAFGAIVTSLVNDIITPLIL
                     NPALKAAKVERIAQLSWHGVGYGNFLSAIINFIFVGTALFFIIKGIEKAQKLTGIKKE
                     KTAEKKPTELEVLQEIKALLEKK"
     gene            complement(16452..17546)
                     /gene="hemH"
                     /locus_tag="VQ540_000920"
     CDS             complement(16452..17546)
                     /gene="hemH"
                     /locus_tag="VQ540_000920"
                     /EC_number="4.98.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrochelatase"
                     /protein_id="HET2544743.1"
                     /translation="MKKAILMMTFGSPEEISFEGVAEFFTNIRRGVRPQDHEIQTLYD
                     NYIRIGGTPLQRITREEVNLVKERLGEEYGIYFANKFSRPFIPDVIKQMETDGVEECI
                     CLILEPHYSFYSVMGYEKFLESKQIQFLVIKDWYQEEVLLNYWADEIAKILKEEVKQD
                     SFKVIFSAHSVPIFALDFGDPYIDQIFENSKLVAEKLGLSSEQYTNTWQSESDIGIPW
                     IKPDVLEYLREQTEHPDHYIFVPISFISEHIEVLFDNDVECYDLCQEFGVNYHRPPMP
                     NTDSRLIDALVNTVRVNENQEFKEFLPEEETFDELVPSDETKNILAESEDLQMPEFVK
                     KLIEKKGRENVKMPYLIKKMLEKAGKLPKE"
     gene            complement(17624..18456)
                     /gene="srtG2"
                     /locus_tag="VQ540_000921"
                     /pseudo
     CDS             complement(17624..18456)
                     /gene="srtG2"
                     /locus_tag="VQ540_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000218039.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PI-2 pilus system class B sortase SrtG2"
     gene            complement(18534..19532)
                     /gene="srtG1"
                     /locus_tag="VQ540_000922"
     CDS             complement(18534..19532)
                     /gene="srtG1"
                     /locus_tag="VQ540_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000851047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PI-2 pilus system class B sortase SrtG1"
                     /protein_id="HET2544744.1"
                     /translation="MKTKREKPKKSLSRRLVLAVDGVINHLLLIFAALIFLFGFYALW
                     DSNQVYSLASSSEYEAYRPVTTQQDELASFSGFSKLQELNPEVLGWINVYGTNIDYPL
                     VQAKDNEKYLNKDSKGEFAATGAIFLDARNNPKFEDFNTIIYGHHVENGVMFGDVAKF
                     ADQEFFDQHRYGSIYYNGVEKGLEIFEMLEVDAYDFNIYDPGIQGEDRQQAYLDHLLS
                     VAMHKRDISLSPSDRIILLSTCFLDVTNGRHIVVAKITDTVPKNTFHTKKSKPFPYSV
                     FDDSSLGRFLSSIPLWIWYLILFVLFLLLIFLLLVLYLILRRRRESKKNARSRPFY"
     gene            complement(19550..20746)
                     /gene="pitB"
                     /locus_tag="VQ540_000923"
     CDS             complement(19550..20746)
                     /gene="pitB"
                     /locus_tag="VQ540_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PI-2 pilus major pilin PitB"
                     /protein_id="HET2544745.1"
                     /translation="MKKTFFKKLFTASIAAITALSVFRGVPTFADDNSAITKANGENN
                     AVVKINKTLNIAEGITTPTATFTFKFTEKTGQSSNGAPYQTGVAIPDRNVEYNKNDHP
                     TADKIQKATEDIFSGVAYGHAGEYVYDVAEAKTGWQAITKNGKTIDAMRYDKRTYEMH
                     VIVKNKVNGGVYISSVYFKENNKSNAPKVEPSEQGVYNLFDNTYTKDASKEPNPDDPS
                     QVDPNAKALTITKKVDGASGDKTRDFQFHIKIQLPSTNKTAETPVTNIIVKHGSKSEV
                     LAVVTPADTVEYNFTLKDGETFTVEQLPAGSKYTVTETGVAGYTDSSIYTTNGAEQTS
                     QGQKNVDFTLTDILIGEKKNDNKVTNKIDDVTPTGLLIDNLPFILMIGLGLAGFVVLS
                     KKRREA"
     gene            complement(20791..21342)
                     /gene="sipA"
                     /locus_tag="VQ540_000924"
     CDS             complement(20791..21342)
                     /gene="sipA"
                     /locus_tag="VQ540_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PI-2 pilus system signal peptidase SipA"
                     /protein_id="HET2544746.1"
                     /translation="MLLKKKHKKPVTQVNRDKSPPSVWGDILYLVSKLLMVGFVLAIL
                     YFFVFGLLRYNDDGMKPALKDGDLVVYYRLDKRYSIGDLLVYSYKGKERVARVIATEG
                     STIDINENGLIINGSPQQEQDIYKETLLYKEGATFPMKVPAGQLFVLGDNRTTAVDSR
                     AFGTIPIQDTQGKVVTVIRRRGF"
     gene            complement(21342..23297)
                     /locus_tag="VQ540_000925"
     CDS             complement(21342..23297)
                     /locus_tag="VQ540_000925"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HET2544747.1"
                     /translation="MDAGIGTGTNINAGLTEAQRLLQSARAGAKKVVILLSDGEANMY
                     YESNSGRTIYNYYSNPNVGRMIDTPYWFTSGLERGMLNISSLIAPKIDGFYSIKFRYY
                     IGSNDSITSLKGYISGYNSGIPNEIFSANNENDLQQKFKEITDKILPLGVHHVTISDV
                     LSKYVQLLPGDASHLRVVKIKDGNEQELNDNQVTIETKKNEQGLVEVTAKFNPSYTLE
                     DDAKYVLKFTVTSSQEAFDAIAGDKTLTSDDAEEADATKLYSNKGAKVAYSYGIGTSR
                     TKIKDYSEKPTFKPSDPLTVPVEIEWKGVDGKSNPSANRPPSVELNLNQKKDGSIKDS
                     YRKVTSPVQTNSFTENTSFAKVAKGYDYELKAPDAPGYTVEVQKTGTKEKPSFKVIYR
                     QLPSLTVKKILEGEQSPNKSFTINVTFSDKDGKPINGKFGNTTVTNGKAQISLKNSQE
                     TALSYLPRDTHYKVEEVENSRTGYHVTYEKQEGTLSEDVQTIVTNHRLPTLSVTKKVT
                     GAFANLLQSFKITINVKDAQNKPLNGSYSAIVNNQKTTLQFTNGKATVDLKKDKTIKI
                     LDLPLNARYSIEEEASSSRGYQVSYDKKEGTLDANKSATVTNNKNSVPETGIDFLSST
                     LVLGVVLPLGGIFFIILLGHLVVNRRK"
     gene            complement(23427..23930)
                     /locus_tag="VQ540_000926"
     CDS             complement(23427..23930)
                     /locus_tag="VQ540_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001102795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adhesin"
                     /protein_id="HET2544748.1"
                     /translation="MNVQYDFKKIQYFTSSLVIFLAILFLCAPINSLRADSITEPQTT
                     LHKTITPISGQKDQYELSLDITSKLGTETQSEPLDVVLVADLSGSMEERDVWSYSSRR
                     YISRIEALKHTLKGVNGRQGLIDTILSNSQNRLSIVGFAGKIDNQYNDRYYNEYYLSY
                     QYGTWPN"
     gene            24289..25512
                     /gene="pepT"
                     /locus_tag="VQ540_000927"
     CDS             24289..25512
                     /gene="pepT"
                     /locus_tag="VQ540_000927"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000222045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HET2544749.1"
                     /translation="MTYPNLLDRFLTYVKVNTRSDEHSTTTPSTQSQVDFATNVLIPE
                     MKRVGLQNVYYLPNGFAIGTLPANDPSLTRKIGFISHMDTADFNAEGVNPQVIENYDG
                     GVIELGNSGFKLDPADFKSLEKYPRQTLITTDGTTLLGADDKSGIAEIMTAIEYLTAH
                     PEIKHCEIRVGFGPDEEIGVGANKFDAEDFDVDFAYTVDGGPLGELQYETFSAAGAEL
                     HFQGRNVHPGTAKGQMVNALQLAIDFHNQLPENDRPELTEGYQGFYHLMDVTGSVEEV
                     RASYIIRDFEKDAFEARKASMQSIADKMNEELGSDRVTLNLTDQYYNMKEVIEKDMTP
                     ITIAKAVMEDLGITPIIEPIRGGTDGSKISFMGIPTPNIFAGGENMHGRFEYVSLQTM
                     ERAVDTIIGIVAYKG"
     gene            complement(25548..26177)
                     /locus_tag="VQ540_000928"
     CDS             complement(25548..26177)
                     /locus_tag="VQ540_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2544750.1"
                     /translation="MNKANQLLEQIHEEGIRQSLAEEVENLKAATNKADADLDEVNSQ
                     VKDVLTRIASALQQEKENAEQDSQTLVLYQKLYDILMSLHSYLESNNGSDADFDKVDA
                     LLDQLSANSKDKTALLESTKAILVLNHQIQSKVSASEETSPARNAEANSDNTSAENQP
                     NATAESNIETASDENKPSNTRDSKPAESTSENETTESSTTTGNQEKPVE"
     gene            26142..26363
                     /locus_tag="VQ540_000929"
     CDS             26142..26363
                     /locus_tag="VQ540_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2544751.1"
                     /translation="MDLFQELICLVQKTFYFFLAICRRLLVAIYHVLLKQESYNPRLQ
                     GLTEIRNPDKTMFVQDAIRFAQQHGFNML"
     gene            complement(26634..26982)
                     /locus_tag="VQ540_000930"
                     /pseudo
     CDS             complement(26634..26982)
                     /locus_tag="VQ540_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669441.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
     gene            complement(27087..27647)
                     /locus_tag="VQ540_000931"
                     /pseudo
     CDS             complement(27087..27647)
                     /locus_tag="VQ540_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669441.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
     gene            complement(27873..30992)
                     /gene="phtE"
                     /locus_tag="VQ540_000932"
     CDS             complement(27873..30992)
                     /gene="phtE"
                     /locus_tag="VQ540_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtE"
                     /protein_id="HET2544752.1"
                     /translation="MKFSKKYIAAGSAVIVSLSLCAYALNQHRSQENKDNNRVSYVDG
                     SQSSQKSENLTPDQISQKEGIQAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDALFSE
                     ELLMKDPNYQLKDADIVNEVKGGYIIKVDGKYYVYLKDAAHADNVRTKDEINRQKQEH
                     VKDNEKVNSNVAVARSQGRYTTNDGYVFNPADIIEDTGNAYIVPHGGHYHYIPKSDLS
                     ASELAAAKAHLAGKNMQPSQLSYSSTASDNNTQSVAKGSTSKPANKSENLQSLLKELY
                     DSPSAQRYSESDGLVFDPAKIISRTPNGVAIPHGDHYHFIPYSKLSALEEKIARMVPI
                     SGTGSTVSTNAKPNEVVSSLGSLSSNPSSLTTSKELSSASDGYIFNPKDIVEETATAY
                     IVRHGDHFHYIPKSNQIGQPTLPNNSLATPSPSLPINPGTSHEKHEEDGYGFDANRII
                     AEDESGFVMSHGDHNHYFFKKDLTEEQIKAAQKHLEEVKTSHNGLDSLSSHEQDYPSN
                     AKEMKDLDKKIEEKIAGIMKQYGVKRESIVVNKEKNAIIYPHGDHHHADPIDEHKPVG
                     IGHSHSNYELFKPEEGVAKKEGNKVYTGEELTNVVNLLKNSTFNNQNFTLANGQKRVS
                     FSFPPELEKKLGINMLVKLITPDGKVLEKVSGKVFGEGVGNIANFELDQPYLPGQTFK
                     YTIASKDYPEVSYDGTFTVPTSLAYKMASQTIFYPFHAGDTYLRVNPQFAVPKGTDAL
                     VRVFDEFHGNAYLENNYKVGEIKLPIPKLNQGTTRTAGNKIPVTFMANAYLDNQSTYI
                     VEVPILEKENQTDKPSILPQFKRNKAQENSKLDEKVEEPKTSEKVEKEKLSETGNSTS
                     NSTLEEVPTVDPVQEKVAKFAESYGMKLENVLFNMDGTIELYLPSGEVIKKNMADFTG
                     EAPQGNGENKPSENGKVSTGTVENQPTENKPADSLPEAPNEKPVKPENSTDNGMLNPE
                     GNVGSDPMLDPALEEAPAVDPVQEKLEKFTASYGLGLDSVIFNMDGTIELRLPSGEVI
                     KKNLSDLIA"
BASE COUNT         8835 a         6360 c         5686 g        10121 t
ORIGIN      
        1 aaaaggatct agtttttatt tttagttaaa ttatgtctat atttttcatt aactcatcaa
       61 taaaaatttg tttgctaata tctctttctt ctgattttgt ttcaaggatt attgctacat
      121 cattcatatt tttaggtaaa taccaaccat ctggcttatc tgaatatccc ttgaagccta
      181 attgattaaa agtagttatt tgaccagtac cttgattgat gttttcttca acttcattaa
      241 agcctatact tctcttgcat aatccctaac ttgatcttct gtccttaaag tcattttcta
      301 ttcctcgtca ctaaaattat cttcaaaact aataatatca ttaggagtgc aagataaagc
      361 cttacatatt ctttctaaat tcttaaatgt aattggttta tcctttccca tttgtgccat
      421 aacatttgtt gtaagtcctg ccatagctat tacatctgtt ttctttagtc ctttttttgc
      481 taactgtatc cataatggtt tatagttaag taccataata tccctctttt tttcttcatt
      541 aaatttattt aattatagca taaatattga tttcattcaa tcttacattg atttagtgat
      601 ttgttttaga gaatttgttg tgttattccg tccttatttt gccataaatt gttttaagtg
      661 ggacctctta tccttaccat ttttacctcc taattttgag tataaaaaag acgatagagt
      721 ttttaatttc tatcgtctga gatttacata ttaaattttc atcacaaaat aagactcttt
      781 aaagaatctt taaattcatt ggtatgctgc ttacaatatc cattattaaa atggatacta
      841 taagcagcac accaactatt tattttttga gttttaaact ttggtagaag tcttgaactc
      901 cttatattta cataactatt tgcctctata actattatga cacgaaacca acaagcaagt
      961 tcaagcatct ccatatcttt attcaaatga ggactaagat attcacaaac tttatcataa
     1021 acctctttat cttttttcat aaaaggggca tacaacttag caaatttatc ctaaaatttt
     1081 ttgttgcctt tatcaatcat ttcaacgctc ctttaaatat aaaaataatc ctatcaatct
     1141 ttatattgag cctattttct aattgatacc ttgcaagaaa ggaataatag ctgttcctat
     1201 accaagtagg aatgtaataa atgcagaaag tcatatactg tcattctttt ctattaaatc
     1261 attttgaagt gtctcaaagc atccatgatg gcttcttctt tttcaggtgt acactgtgga
     1321 ataatttgtt tatccttttt agacttgttg taatgttctc gtaattctat tccacatttc
     1381 ttttttatct gtgcaatata taatgtcgaa acttttaatt caaatttatt ccaaacatat
     1441 tctttgattt gagcatatgt tgctttgctc tccgcacttg tcaaatccat ctcatccagc
     1501 tcaatttcaa cacttatgtg cttatcgaca tcgagtttgg acaaaagtgc taccgtctcg
     1561 acgtgatgcg tttgaggaaa tagatccacc ggctggactt tcttcaattc atatcccaat
     1621 tcttggtaga gtttgatatc acgcgccatg gttgcgacat tgcaggagat ataggcgatg
     1681 cgatcggctc ctgtttgggc gcttgctttg ataaagcttt ctgtcaagcc cttgcgtgga
     1741 ggatcaacca agataacggt tggttgaata ccttccttga gccatttctt catggcattt
     1801 tcagccgtgt cacagacata gtgggcatta gtaatcttgt tcaaagaagc attcttctgg
     1861 ctattctcaa ccgcttctgg aatcagttca acaccgtaga cttctttgac atgcttggcg
     1921 actgataaac caatggttcc aataccagaa taagcatcaa taaccacgtc atcttttttt
     1981 aactctgcaa agtcaatggc tgtttgatag agtttctccg ccatttcagt attgacttgg
     2041 taaaaggctg ggccagcgat ttggaagtca tttcccaaca tctggtccgt aatatagtct
     2101 tgaccataaa gagtgcacca ctccttacca aaaatcgcat tggtattctg gtcgttgata
     2161 ttttgcatga cagacacaat ctctgggaac tgcttgataa cttgttcaat caattggtca
     2221 acacgaaaaa cttttggacg agttgtcacc aaaacgacca tgatttgtcc tgaatagtga
     2281 ccacgacgca ccacaagatt ccgaatcaat ccagactgtt ccttttcgtc ataaggtttt
     2341 aaatcaaaac gacggagcag gtctcgaaga gctactacga cttggtcaat gacaggatcc
     2401 tggataaaga aatcttcaag gggcatgagg ttgtgcgaat tcttacggaa aaatcctgtt
     2461 tccaagacac cattcactcg acgaacgggc acctgcgcct tattgcgata cttgactgga
     2521 tgttccatac caagcgtttc agcaacttct acatctgcaa ttccagcaat cttgtagaga
     2581 ctgtccttga cttgcttggt tttaaacttg agctgttctg gataagaaag gtgtcctaaa
     2641 tccgcgattc ctgaacgcag gtaagccaaa tctagatctt gattacggtg tagtgactgg
     2701 acaaggtatt tttcaacttt tccaaagcca atctttttat tgaccttgag gacacgcatg
     2761 agaatttttt cactcggtaa agcattctct acaaaaaaga ccaaaccatc taccttggca
     2821 actcctgccc cttcatgggt caaatcaaca atttcaactt ctacaatatc atttttcttt
     2881 aacattcttt tctctttcta ttggccgaca aaaaagacgg caacgttacg attaccatcc
     2941 attataccat gaaatttctt aagaaccaaa actcttgaag aagttgacaa gggcttgcca
     3001 gagggagctt aagaagttac caccgtcctc tagcgcctta tccgcatcaa agttaaggtt
     3061 gatattttta aaactgtcgc cagcttgtga tacgatgctt tgtttaaggt catttagggt
     3121 tttagtgaaa tctgcattgc tgaggatatc actctttgag agattcaagg caaaattgat
     3181 gatgatattg atctggtttc ctgttatgac ctgatcaagt ttgtaatttt ttaaggtatc
     3241 ttcaacaatc ttgcggacat cttcttctgt cagatttccc ttgctttctt tagctttggc
     3301 gagtcctgac ttgatatcag ctagggcaac gtttaattta ttagcatcat agcctgattt
     3361 gtccttgttt tcagcattga tatctgacaa agcctttagc tcttcttgag ccaaatcttt
     3421 attggcttgc ggcaccttgg ctccattagc ttctagcgaa tagtagatcc cagccaaagc
     3481 actctcacct gtaactggaa taggggctgc tacagtgatt ttggcatgtt ccatacccag
     3541 cgttactgct gcgtttcggt acatatcctg agtcacctta gtgatatttt ctggtgtttc
     3601 aatcttgacc tcaagtggcg atttgtcacc tagcttttga atcttggctg atgaatacaa
     3661 ctgtaagcta gagtcattgg ccacattcat gattttagaa taaacatcag gtgtcatggt
     3721 cttgagttct ttggtatctg ttgaggcatt gtagcccagt tttttaagag tttgattttt
     3781 ttggtcttca gatagggagg aacctaggac atattcaggt tggacatagg tttcatcgat
     3841 aaccttttga acatctgttg ctgcatggac gctattcata gctgttactg cccacaagac
     3901 cgcagcactg gtcagaaaga gtttctttct catagggaat ttcctccttt acttttctag
     3961 agtaatatat ctatcttaaa gaaaacttat aacaaaaaca cctggtctag ccagatgttg
     4021 aaaagagagt gaaacatttg atgatgtaaa ggttaagtcg tacctgtcta gaataataat
     4081 agtttcctcc atttacatag agttcagcac cgtgaaaaat ggaaatgggg tgaatataac
     4141 tataagtctt tccagtcgta ttaccaagca agggggcaac agtctcacga gagtactgtt
     4201 tggctagagc caaggtattt tccttgccat tttgggcgat aaaatcgata taggcaggtc
     4261 caaaattata ggcttgaaca gctgtccaga tatctacccc cttcttctgc gccagataga
     4321 gattgcctgt cagagtttga atgccttgcc gaatgctaga ggcattatca ttgatggtgt
     4381 tggttgaacc acttgcagac tcactagact gcataacatc gccttctttt ccttttgttt
     4441 cagtataaat catagcaagc acaagctctt cgtttgctgg ggtgtctttt tcactcaaga
     4501 tttctcgcac catgggttga taggtcatga cttgtttgac atcttgatga acgcggtaag
     4561 ctttatagcc agcaaaaagg aagactgcta gtacaagcac tcttcgaatt cgtttaaaca
     4621 ttatttactt tggatatcct cgatattttt gattaagata gagtaggttc cattttcctt
     4681 ttggataaac tcaacagact cggcgtcttg atagacgtta ttgggaacga tgagctcaat
     4741 tccatttgat aaggagagtt tttggttttc aaatttcttt aattggcgac tggcatcaat
     4801 ttcatcaaat tgaacaggtt ctggtacggc ttctttgact tggtcaataa agctcaaacg
     4861 agccgtcaga ttgttgtcaa aaaggtcatt agccaatttc tcaggtgaca attcattgct
     4921 ttcttctagg ttgttgaaaa tcgctgattt gaccttggat tgaaattgaa aatcatctgt
     4981 gttaaaagat tcagcaattc tctgggctgt tttttccagt tccttgatag attttttagg
     5041 agaaatctta ggagcgacag caagaagatt atctgaaaaa tagttcaaaa aagtcccgtt
     5101 gtacttgatt cgtttttcaa tcaggtgata cttgcgactc tgaagattga ccaccaaggc
     5161 ctcgtcagca cccgttccaa atccaggcag gttattctga gtcagcttga ttggattatc
     5221 aacttctcct ccgaggtggg tcaaggtctc ccgcagggca attcgcaaga aagcgaaatg
     5281 ttctacacct tctttagaaa attgaacaaa aatcaagtca ttggtcttga gattttcaga
     5341 aatgctaaac tcctctttcc agagattagc cagcgttact gatgtctcca acaaatcgtc
     5401 tgtaatatga ttgaagaagg gattttcttc ttcgaaaatc ccagtcttgg cttcatctga
     5461 atacacatgt tcaatttttt tacgtaggta ttcttcgatt tttggagtaa tattgagaaa
     5521 cttatctgct aagaacagct cggtatcatc cggactgaac tggtgaataa tggctttctt
     5581 aatataaatg tccataaaag ttttattcct cgtataatgg gaaggcatct gtcaattctt
     5641 tgactgcact tctcacttct tctaatacag cctcattttc tgaattctta agggttttaa
     5701 tgatgagttc agccactttg cgactttctt cttcaccaaa tccacgtgca gtaatagctg
     5761 ctgctccgat acgaatccca cttgtcttga atggtgacaa ggtttcgtaa gggattgaat
     5821 ttttatttag ggtaatattg acttcatcca gcaagttttg agcaactttt ccgttttcta
     5881 caaccttagt cacatcaaca aggaagagat ggttttcagt tccacctgaa ataatacgga
     5941 aatcagggtc ttgcaagaag acatctgcca tagccttgct gttcttaatt acattggcag
     6001 catattcctt gaaggctgga tccaaaactt ctttgaagga aactgcctta gccgccacaa
     6061 catgctctaa aggaccgccc tgaatacctg ggaaaatagc tgaattgatt tttttagcaa
     6121 gttcttcgtc attggtcaaa atcaaaccac cacgaggtcc acgaagggtt ttgtgggtcg
     6181 ttgttgtagt gatatgagcg tatggcactg ggcttgggtg aagaccagct gcaaccaagc
     6241 cagcgatgtg ggccatatca accataagct tcgcaccgac agcatctgcg atttcacgga
     6301 attttgaaaa gtcaataatt tgagaatagg ctgaagcacc agctacaatc agttttggtt
     6361 ttacttcttg ggcttgtttc aagatagcat caaagtctaa gagttccgtt tcaggatcaa
     6421 cactataaga aacaaagttg taggtttgac cagagaagct aacaggagcc ccatgagtca
     6481 aatgaccacc tgatgccaaa tccattccca taaccgtatc acctggctca atcaaggaca
     6541 tgtaagccgc acagttggcc tgacttcctg agtgaggttg gacattggca aatttagcac
     6601 cgaaaatttc ttttgcgcgt tcaatagcaa gagtctctac aacgtctact acatcagttc
     6661 caccataata acggcgtcct gggtaaccct cggcatattt atttgtcaag atagaccctt
     6721 gagctgccat aacagccttg gaaactacgt tttccgaagc aattaactcg atattatttt
     6781 gttggcgttc ttcttctttg gcaatagcat tccagagatc agcatcatat gctttaaaat
     6841 catctttgtc aaaaatcata ggtcttctcc tttattgtgt gactagtcca ttagtttgat
     6901 tttacaataa gaaaatcaaa ctaaaagatg cgaataaacc gtttctgcat tttatcacaa
     6961 gtatagccaa ctttttcata aaatgcatga gcacccagac gatgattggc agaatttaag
     7021 cggataaacc cataaccaca tcttttggct tcttgttcca acccttgtag taaactttta
     7081 ccgatacctt gaccttgcgc ttgaggtgaa actgctaaag ctaagatatt aaatcctgct
     7141 ttggaataga gtgattcgta aacttcagcg tggacatatc caagtaagac atgattagct
     7201 gcatcctcat agccaagtag gaaatgatgg gaatcctgag acagtctagc tagttggcta
     7261 gccgtttcct ctggactaaa agtataaccc aaagcctctt ggttgatgtc acatatcgct
     7321 ttcacatctg tttcttgcaa atctcttagc atttcaagcc tcctcaaaag aaatctctgg
     7381 caaccgagca agaatatctt ctcgtttaat tgcgccttgg cgtaagattt tcaccttgtc
     7441 tccagacaaa tccacaatag ttgaatcctg tccagttaga aaagcatcgt cttccagacc
     7501 cagaacctct tggtcaaaat ccttcagaat ttgttcaaag gttacaccac ttgcctgacc
     7561 tgagatattg gcagacggcc caatcaaggg acctgtctct cgaattaaat ccagtgtgat
     7621 agggtgactg ggcatccgaa atccaatagt tgcaaggtca gaatttaccc aatagggaac
     7681 tcggtcattg gcttcgagaa taatggtcaa gggacctggc aaaaaggtct ctacaagttt
     7741 ttgtagataa gttggctgat tcttagaaaa gtgcaagata tcctcgaaag aggcgatatt
     7801 gagattgagt gccttatctc taggacgacg tttgagttgg taaacatggt caactgcttt
     7861 ttcatctaag gccttggcaa aaagaccata aacagtctct gtaggtagaa cgacagctcc
     7921 accattttcc aactcttgtc taatcctgtc catcatcaac cacaaccatc ctattttgac
     7981 caaattggtc tttgagtgtt cgaacttttt tttcaggaag atgttttcta aaaagttcgg
     8041 gaacactttg accttgcttg tatccaattt caaggtaaat cttaccacca tccttgagat
     8101 agtcttttgc atcttccgca attctacagt aaatagctag gccatcctcg tctgcaaaga
     8161 gagctagatg aggctccgaa tgcaaaacat tcaagcctac ctctgactca tcttcacgag
     8221 agatataggg tggattggat acaattatat catatttttc agaaatttct gcaaaacaat
     8281 cagatttttt aaaaaatata ttaagatttt gatcgctagc attctctgat gcaagctcta
     8341 aggcctcttg agaaacatct gctgctgtca ctgaccaatc tggtctattt tttgctagag
     8401 cgagagcaat agctccacta cctgttccaa tatccagaac tgagagattc gtctcaagat
     8461 tttcagttag aataagctcc actaactcct ctgtttctgg acgaggaatc aaaacccgtt
     8521 catccacctt taaatgcatt ccataaaaat ctgcctgtcc aatgatgtac tgagctggct
     8581 tgtgagctgc tagttgctgg taaatatctt ctacaaattg tttttcttcc tctgttgtca
     8641 cctcctgctg gagggcaaaa ataaagtctg taaaagatag atttttcaga ctacgataga
     8701 caaaagagag gctttccgct tcctctcctt gtcttatcaa ctcttcttca aaatttgaaa
     8761 ataattgagc taatttcatt atttgtttaa ttcttctagt ttttgtgttt ggtcataaag
     8821 caccaaggca tccacaactt cgtccaattt accagacaaa atcgtatcta gtttttggag
     8881 ggtcaagccg atacggtggt ctgtgacacg gttttgaggg aagttataag ttcggatccg
     8941 ttctgaacgg tcaccagtac cgattgtcga cttacgctca gcgtcttgtt catcctgagc
     9001 aatctgagca aagtggtcag cgacgcgtgc acggataatc ttcatagcct tctcacggtt
     9061 cttctgctgg gtacgttctt cctgcatctc aaccttgata ttggttggca agtgaacgat
     9121 acgaacggca gtcgcaacct tattgacgtt ctgtccacca gcacctgatg cgtggtaaat
     9181 atcaacacga agatcttttg gatcgatatc gtattctact tcttcgactt caggcatgac
     9241 aagaactgtg gcagttgagg tatgaacacg accttggctt tctgtcacgg ggacacgctg
     9301 cacacggtgg gcacctgatt cgtacttaag cttagagtat acagactgac ctgaaaccat
     9361 agcaaccact tctttaaacc caccgacacc attcatagag gcttccatga cttcaaagcg
     9421 ccagccttgg gcttccgcat acttttggta catagttagc aaatctccag cgaaaagtgc
     9481 cgcttcgtct ccaccagctg ctccacggat ttcaaggatg atattcttgt catcgtttgg
     9541 atcctttgga aggagcaaaa ttttcagttt ttcttcatat tcttcttttt cagccttggc
     9601 atctttgagt tcttgcttgg ccatttcttc caagtccgca tctccgcctg attccttaat
     9661 catctcttcg gcatcgacga tattttgaag gacttgttta tactcacggt aggctattac
     9721 ggtatcacga ttggaagctt cttcttttga aagctccata aaacgcttgg tgtctgaaac
     9781 gacatcaggg tcactcagca attctcctag ttcttcataa cggtcttcta cagcttgtag
     9841 ttgatcatag atgttcattt ttcttcattc tccttattga tttcaggggc aaaataatgt
     9901 ttacggcaaa ccgagatata ggtttcatta ccaccaattt ggatctgttc tccatcgtaa
     9961 acgggcagtc catcctgtgt tcgcaacacc atggtcgcct ttttcttgca atactgacag
    10021 atggtcttga tttcgtcaat cttgtctgct aaaagcaaga gatatttgga accttcgaac
    10081 aattcattgc gaaagtcatt tttcaagcca aaagccatga cgggtatgtc taactcgtcc
    10141 acaacacgag ctaggtcata aacatggtgg cgtttgagaa actgggcttc atcgaccaac
    10201 acacagtaag gtttttctgg taggcctcgg atatagccaa agatatccgt tgtttcctca
    10261 atcgcaaggg cagggcgttt catgccaatt cgactcgaca catagccaac accgtcacgc
    10321 gtatccagag ctgaagtcat aatcacaaca ccttttcctt gctcctcata gttataggcc
    10381 accttgagaa tctcgattgt ctttccagag ttcatggtcc cataacgata atacaactgt
    10441 gccatgtttc ttgcttcacg tccatttcta aatttttgct acattctagt atatcataat
    10501 tttcttaagc tttaaacggc aaaatgtggt aaaatggaag aaatcaaaac tagtggagga
    10561 agctattatg ccatttgtac gcatcgattt atttgaagga cgcacgctcg agcaaaagaa
    10621 agctcttgct aaggaagtaa cggaagcagt tgtccgcaac actggagccc ctcaatctgc
    10681 tgtccatgtc atcatcaacg acatgccaga aggaacttac ttcccacaag gggaaatgcg
    10741 tactaaataa gctagcttaa gcagaattgc ttaggctttt tcaatctcca agtagcattc
    10801 attgaagaaa tatcctaaat ttgttacaat ttgaaaagaa acttggagaa tttccaagaa
    10861 aagagctatt aattaaagga aacattatga ttacacgtga atttgatacc atcgctgcta
    10921 tctctactcc actaggtgaa ggggctattg gtattgtccg cctgagcgga acagacagtt
    10981 ttgctattgc gcaaaagatt tttaaaggaa aagacttgaa caaggttgcc agccacactc
    11041 tcaactacgg tcacattatt gatcctctga ctggtaaagt catggacgag gttatggttg
    11101 gggctatgaa gtctccaaag accttcactc gtgaggatat tatcgagatt aacacccacg
    11161 gtggtattgc ggtgaccaat gagattctcc agctagctat ccgtgaagga gctcggttgg
    11221 cagaacctgg tgaatttacc aaacgtgcct ttttaaacgg tcgcgtagat ttgacacagg
    11281 ccgaggcggt gatggatatc atccgcgcca agacagacaa ggccatgaac atcgcggtca
    11341 aacaacttga tggttccctt tctgatctta tcaataatat ccgtcaagaa atccttaaca
    11401 cacttgccca agttgaggtc aatatcgact atcctgagta tgacgatgtt gaggaagcca
    11461 ctactgctgt tgtccgagag aagacaatgg agtttgagca attactaacc aagctcctta
    11521 ggacagcacg tcgtggtaaa atccttcgtg aaggaatttc aacggctatc attggacgtc
    11581 ccaacgttgg gaaatcaagc cttctcaaca acctcttgcg tgaggacaag gctatcgtaa
    11641 ccgatatcgc tgggacaaca cgagatgtca tcgaagagta cgtcaacatc aatggtgtac
    11701 ctctcaaatt gattgataca gctggtattc gtgaaacgga tgatatagtg gaacaaatcg
    11761 gtgttgagcg ttcgaaaaaa gccctcaagg aagccaactt ggttctacta gtgctaaatg
    11821 ccagtgaacc actgactgcg caagacagac aacttcttga aattagccaa gataccaatc
    11881 gcattattct acttaataaa accgacctgc cagaaacgat tgaaacttcg aaactacctg
    11941 aagacgttat ccgtatttca gtccttaaaa accaaaacat cgacaagatt gaagagcgaa
    12001 tcaacaacct cttctttgaa aatgctggct tgattgagca agatgctact tacttgtcaa
    12061 acgcccgtca catttccctg attgaaaaag cagttgaaag cctacaagcc gttaatcaag
    12121 gtcttgagct ggggatgcca gttgatttgc ttcaagttga cttgactcgt acttgggaaa
    12181 tcctcggaga aatcactggg gatgctgctc cagatgaact catcacccaa ctctttagcc
    12241 aattctgttt aggaaaataa gaaaaatcca tgatccttca ttcggtcatg gattttattg
    12301 tctttattag taatctggtc ttaagacccc tgttacagtt gccttagttg cttcgtagtc
    12361 gccatctacg acaaccttga taatgcgttt ggcatcttct tctggtgctg gaacaagagg
    12421 tagacgagtg ggtccagctt caaatcccat atagttaaga attgccttaa ctggagcagg
    12481 acttggataa gagaagagag cattaacctt aggaatgaat ttacgctgaa ttgctgcggc
    12541 tttcttcata tcgctttctg caatggcagt aaacatctcg tgcatttcat ccccatttgt
    12601 atgagaggca acagaaataa ccccatccgc cccaaggttc atggcatgga aagcatctcc
    12661 atcctcacct gtataaatca agaactcttc aggcttgtgc tcaatcaagt aagccatatt
    12721 agccaagcta gtacattctt tgacaccgat aatatttgga tggtcagcca agcgaagcat
    12781 ggtttctgga gtcaattcga caactacacg ccctggaatg ttatagataa taattggtag
    12841 gtcagaagca tctgcaatag tcttaaagtg ctgatacatc ccttcttgag aaggtttgtt
    12901 gtagtaagga acaatagcaa gcccagctgc gaaaccacca aattccgcta cttctttgac
    12961 aaactcaata gagtcacgcg tatcattagt acctacaccc gcaatcaaag gaacgcgtcc
    13021 attgacaacc ttttgtacag ccgcaaacaa ctccaactcc tcatcgtggg tcaaagttgg
    13081 actctcagca gtcgttcctg cgagaagaat tccatccgta tgatgggcca ataaatgctc
    13141 aatcaaggct ggaatagcat caaagttaat agaaccatcc tcatgaaagg gggtaataaa
    13201 ggctgtaatg attttacatt cttttaaatc ttgataagac atgaaaacac ctctctattt
    13261 caaagaagga gttcatctga actcctaaac gatatgacta ttttaattca aatttcaatt
    13321 cggctgttgg acgaaccaat ccacgttcat gaagagtttc agcaatctga actgagttcc
    13381 aagcagcacc tttgagaagg ttatctgaaa caacccacat gtgaattcct ttttctgcat
    13441 ccaagtcttt acggatacga ccaacaaagg tatcacgcga accaactgca ttgatagctt
    13501 gaggatagat ttgatgagct acatcatctt caagaacagc acctgggaag gctgcgatag
    13561 ctgcttttac ttcttcgatt ggagccactt cttttgtttc gatataaaca gactcagagt
    13621 gagctgacaa gactggaata cgcacacatg ttgcagatac tgcaatgcta tcatcttcca
    13681 taattttctt agtttccttg gtcatcttca tctcttcgta cgtgtaatca ttatcagtga
    13741 aaacatcaat ttgtggaaga gcgttaaagg cgataggata atgtttcttg tcaccacctg
    13801 aaggcaaaat ttccgcatgc aaatcacatg gtttcacacc atcattcaag acttcacgaa
    13861 gttcacgttg tgtctcaaga attgctccca taccagcacc tgaaacggct tgataagttg
    13921 aaacaatgat acggtccaag ccccattttt ggcgaaccgg ctcaagagcc accatcattt
    13981 ggattgttga acaattaggg caggcaatga ttccgttgtg ggcatcaagt gcatgagcat
    14041 tgacctctgg aacaaccaaa ggaacatctg gattttgacg gaaataagat gtattatcca
    14101 ctactaccac gccagctttt actgcgtatg gtgcatactt agctgatgta gaactacctg
    14161 ctgaaaagag agcaatatca actccttcaa aagctgtttc agtcgtttct tcaattgtaa
    14221 tatcttgatc tttaaatttc aatgacttac ctgctgaacg tgcagaagca aggtaacgga
    14281 ttttatcgat tggaagtgtt gattcttcca acatttttat catctgagca ccgacagcac
    14341 ctgtcgcgcc gactacagca actgtatatc ccataaataa cctctttcgg aattttctaa
    14401 aaatttctat aatagaagta ttatactact ttttccatga attgcaaagc tttttcatca
    14461 ttttttggaa aataaaaatc ccagtcgcta gactagggac taagaggcat cttcatgtga
    14521 tgagcaggtt cacacaactc atcaaggtcc gctcctgcgt tatgacctcc ttatgctcaa
    14581 tagtagtccg aagactacct atcgactcat cgcatattct atattactag agatacttga
    14641 ttttgtcaat aagaaatttt ttcgatcgag tataacaaaa aactctcgta ttcaagagtt
    14701 tccctataca tatcatgcta attgccggga tcgaaccggc gacctcatcc ttaccatgga
    14761 tgcgctctgc caactgagct aaatcagctt acttaagaag tatactatat tcagaaaaac
    14821 ttgtcaagtt tccttagaaa ttttccatag gaaaaagcca ggtaagaact acctagctta
    14881 tcttcttcta tttacttaaa tcaattcgac gaccaatttt accaataata atcgccccaa
    14941 taatcaatga agcaaattca ccgattcctg ttgtaaacca agtaaggaag aatggtaatt
    15001 ctgctacaat atttaactct gcagcgatag taaacatgga aattgaaaag aggattgaaa
    15061 agaagaaatg atcttttcga atcaatccgt taaagaggta atccttgcta tattttgcaa
    15121 aaagccaaac acctaaactg aggaatacta aggttgaacc accaccaaca aagacatcta
    15181 gcagtccgaa gctaaagaaa ttagcaatca tacaaccgat ggtaactccg atgatgtact
    15241 taggattgta aaaagccata aagttcatca tttctgaaat acgaaactga taagcaccat
    15301 agctgatggc atttaggggc ggtgtgacag tcaaaacgac gtagatagca gcgacgattg
    15361 caatatctgc aatatcacga atagttaatt ttttcatctt ttctcctttg gcggttgccc
    15421 gcgtgtaata tgcttggtga aagaagctaa gcaccaaggg ttgctttatt caaccctact
    15481 agtatagcac aatagcctgc tttatgctat acttaacaca tgaaaattcc tattcaaaaa
    15541 ttttttaaca atgaaatctt agcctatctc ttttttggcc ttgcgacaac tctagtttcg
    15601 attctctcac gactagtcat ttatcaacta agtcatcagg aactcctggc tactgcccta
    15661 gcaaatatta tcggtatcct atttgccttt atcacaaatg atacgattgt atttaagcaa
    15721 aaaaagaaaa atagacttat ccgtttagtg aaattttctc ttgctcgcct ttctactttt
    15781 ctgttagact tgtttttaac ttttctcttt gtaacccaat ttcctcacat tatagggcaa
    15841 ttcgtaactg aaaacattga taagataaat gctattgaaa caataattgc acaaatattc
    15901 attattatca tcaattatat attgagcaag gcctatattt ttagaaaata atgctccatt
    15961 tatgagcctt ttaattgcct tctataatga tttaggatac aatgaaacac gaaacattga
    16021 aaggaaaaca gtatgttaaa aaatctaaaa tcgttcttgc ttcgaggaaa tgttattgac
    16081 cttgctgtcg gtgttgtaat tgcctctgct tttggtgcta tcgttacttc acttgtaaac
    16141 gacattatca ctcctcttat tttaaatccc gctttgaaag ctgctaaagt tgaacgtatc
    16201 gctcaacttt cttggcatgg agtcggctat ggtaacttct taagtgctat tatcaatttt
    16261 atctttgtgg gtaccgccct cttctttatt atcaagggca ttgaaaaagc acagaaactg
    16321 actggcataa agaaagaaaa aactgccgaa aaaaaaccaa ccgaattgga agtccttcaa
    16381 gaaataaaag ctctccttga gaaaaaataa tcgattaaaa ggatctagcg caaagctaaa
    16441 tccttttttc tttactcttt gggtaacttg cctgcttttt caagcatttt tttgatcaga
    16501 taaggcatct taacattctc ccgccctttt ttctcaatca gttttttcac aaattctggc
    16561 atttgtaaat cttcagattc agctaaaatg tttttcgtct cgtctgaagg aactaactca
    16621 tcaaaggtct cttcttctgg gagaaattcc ttaaactctt gattttcatt gactctaact
    16681 gtattgacca aagcatcaat caaacgagaa tctgtatttg gcattggtgg acgatggtag
    16741 tttaccccaa attcctggca taagtcataa cattctacat cattgtcaaa caagacctca
    16801 atatgctcac tgatgaaact aataggtaca aaaatataat ggtctggatg ttctgtctgt
    16861 tctctgagat actccaaaac atctggttta atccatggaa taccaatatc actctcactc
    16921 tgccaagtgt tggtatattg ttctgaactc aagcccagtt tttcagcgac tagcttgcta
    16981 ttttcgaaaa tttggtctat ataaggatca ccaaagtcca aggcaaaaat gggcacacta
    17041 tgggctgaaa agatgacttt aaagctgtct tgctttactt cttcttttaa aatcttagca
    17101 atttcatctg cccaatagtt taagagcact tcttcctgat accagtcctt aatgaccaaa
    17161 aattgaattt gtttgctttc taaaaatttt tcatagccca tgacagagta gaaagaataa
    17221 tggggctcca aaatcaagca gatacattct tcaacaccat cagtttccat ctgcttgatc
    17281 acgtctggaa taaagggacg agaaaatttg ttggcaaagt agataccgta ctcctcccct
    17341 aaacgttctt tgactaaatt gacctcctca cgtgtaatcc gctgcaaagg cgtcccaccg
    17401 atacgaatat agttgtcata gagagtctgg atttcgtggt cttggggtct aactccacga
    17461 cgaatgtttg taaagaattc tgctactcct tcaaaactaa tctcctctgg agatccaaag
    17521 gtcatcatta atatggcttt tttcatgtta tcatccttat gatattattt tctctatcca
    17581 ttctatcatg aaagaaaaaa atagtaaacg tttcctacgt ctactatttc ttttgctctt
    17641 ttgttttttt atctcgtctt ataattagga tgataaggac aagaagtaag aggacgataa
    17701 taaggagtag aaaggctaga atgtaaatcc aatgactggg aattccgtga tcgaaatacc
    17761 gtgttcctac tgcttcccca ctttcatcct gtgctacttt caccggtgca tccgttattt
    17821 tagctaaaag gatatgtcgt ccattagtta tgttaaggaa acatctcgct tgtacttggc
    17881 tttacttagc agatattgat agtaagcctg gtgttcctca tccttggaac tcaaggttcg
    17941 ataaatctcc gtgtcatagg catccacttc taaaatccca aaaatttcaa gaccacgttc
    18001 tcgaccattg tagtagatag aaccgtagcg atgctggtcg aagaattcct tatcagcaaa
    18061 tttcttaatc tcaccgaaca tagcccctga agccatagag tgtccgtaga tgatcgtatt
    18121 aaaatcagta aagttgggat taaagcgata gtcgagaaaa attgatccca ttatcgtata
    18181 atcgccaaag gcattgcggt caaggtattt gacattatcc tgactttgta gaagcggata
    18241 gtctaccttg gtcccatcaa ggctaatcca accgcaaaca tctttgttca agtgctgtag
    18301 ggtttcaaaa cctgtgctcg aagcatcctt ttcaatagga ttatagtgat catagtcact
    18361 tgcttctact actctctgcc aactaaaaag agctacaaaa acacagaaga ataccagaaa
    18421 tacgttttta aatcgcgctc ttttttgaac cgtcatcagc actcctttct atgcgagatt
    18481 tcttaaaagg aaaggaggcg ggacaaaacc gcctcttttc tattcaccct tagtcagtaa
    18541 aagggtctgc ttcttgcatt ttttttactc tctcttctac gacgtaggat caagtagagg
    18601 acaaggagta agaaaatcaa gagcaagaac aatacaaaca agataaggta ccaaatccat
    18661 agtgggattg atgagaggaa acgtccaaga gacgagtcat caaagacact gtatggaaat
    18721 ggttttgatt tttttgtatg gaaagtattt ttagggacgg tgtctgtaat ctttgcgact
    18781 acgatatgac gaccattggt cacatcgaga aaacaggtac tgagtaggat gatacgatca
    18841 ctcggtgaga gtgagatatc ccgcttgtgc atggcgactg agagcaggtg gtctagatag
    18901 gcctgctggc ggtcctcacc ctgtattcct ggatcataga tgttaaagtc ataggcatca
    18961 acctccaaca tctcaaagat ctcgagccct ttttccacac cattgtagta tatactaccg
    19021 taacgatgct ggtcaaaaaa ttcctgatca gcaaacttag ccacatcacc aaacatgacc
    19081 ccattttcta cgtggtgccc gtagataatg gtattaaagt cttcgaactt aggattattt
    19141 cgtgcatcga gaaagatagc gcctgtcgct gcaaactcac ctttggagtc cttgttgaga
    19201 tacttttcat tgtccttggc ttggactaag ggatagtcga tattggtgcc atagacattg
    19261 atccaaccga ggacttcggg attgagttct tggagtttgc tgaagcctga aaaactggcc
    19321 agctcatcct gttgcgtcgt gacaggtcga taagcttcgt actcacttga cgaagctaag
    19381 gagtagactt ggttggaatc ccaaagggcg tagaaaccaa agagaaagat caaagctgca
    19441 aaaatgagca gcaagtgatt gatcacccca tccacagcaa gaacgagacg cctagacaga
    19501 ctcttttttg gtttctcacg cttggttttc atcatctgcc cccagccgtt taggcttctc
    19561 tacgtttttt agacaagaca acaaatccag ccaaaccaag accaatcatc aaaatgaatg
    19621 gaaggttatc aatcaagaga ccagtaggag taacgtcgtc gattttgtta gtaactttgt
    19681 tgtcgttttt cttttcacct atgaggatat ctgttaatgt aaaatctaca tttttttgtc
    19741 cttgagatgt ttgttctgca ccatttgtag tataaattga tgaatctgta taacctgcta
    19801 ctccagtttc agttactgta tatttagaac ctgctggtag ttgttcaact gtaaatgttt
    19861 caccatcttt aagagtaaaa ttgtactcaa ctgtatctgc tggggtcact actgccaaca
    19921 cctctgactt agatccatgt tttactataa tattcgtaac aggggtttct gctgttttat
    19981 ttgtacttgg aagttgaatc ttgatatgga attggaaatc tcttgtttta tcccctgaag
    20041 ctccatcaac ttttttagta attgttaatg ctttcgcatt ggggtctact tgactcggat
    20101 catcaggatt aggctcctta cttgcgtctt tggtatatgt gttatcaaat aaattataaa
    20161 cgccttgttc acttggttct actttagggg cgttagattt attattttcc ttaaagtata
    20221 ctgatgaaat atagacacca ccatttactt tattcttaac aataacgtgc atttcatatg
    20281 tacgtttgtc gtatctcatg gcatcaattg ttttaccatt tttggtaatc gcctgccatc
    20341 cagtttttgc ttccgctaca tcataaacgt attcaccagc atggccataa gcaactcccg
    20401 aaaaaatgtc ttctgttgct ttttgaatct tatcagcagt tgggtgatca tttttattgt
    20461 attctacatt tctatctgga attgcaactc cggtttgata tggcgcaccg ttagaagatt
    20521 gtcctgtttt ttctgtaaac ttaaatgtaa atgtcgctgt tggtgttgtt attccctctg
    20581 caatattcaa cgttttatta atcttcacaa cagcattatt ttcaccattt gctttggtta
    20641 ttgctgaatt atcatccgca aaagtcggga cacctctgaa tacggacaaa gcggttatag
    20701 ctgcaatgct tgcagtgaat agctttttaa agaatgtttt tttcatgatt atttcttttg
    20761 tttttttatt ttcttttttc attatgatca tcaaaagcct cgtcttctaa tgactgttac
    20821 aactttgcct tgagtatcct gtatagggat ggttccaaaa gcacgactgt ctacagccgt
    20881 tgttcgattg tccccgagga caaaaagttg tcctgctggg actttcatcg ggaaggttgc
    20941 cccttcctta tagagcagcg tttctttgta gatatcttgc tcttgttgag gagaaccgtt
    21001 gatgatgaga ccattttcgt ttatatcgat tgtacttcct tcggttgcta tgacacgcgc
    21061 cactctttcc ttacctttat aactatagac tagcaaatca ccaatcgaat agcgtttatc
    21121 caacctataa tagacgacca agtcgccatc ttttaaggcg ggcttcatgc catcgtcatt
    21181 gtatcttaat aatccaaaga cgaaaaagta aaggatggct agtacaaatc caaccatcag
    21241 aagtttactg actaagtaaa ggatatctcc ccagacactc ggcggagact tatcccgatt
    21301 gacttgtgtt actggtttct tatgtttctt tttaagcagc atcacttcct cctattcacc
    21361 acaaggtgac caagtaagat gataaagaag atccctccta gaggaagaac gactccaagc
    21421 acgagagtgc tactcaagaa gtcaattccc gtttcaggta cgctgttttt attattcgtg
    21481 actgtcgcag acttatttgc atcaagagtt ccttcttttt tatcatagga cacctgatac
    21541 ccacgagacg aacttgcttc ttcttcgata ctataacgag catttagagg aaggtcgaga
    21601 atcttgatgg ttttatcttt ctttagatca actgtcgcct taccattggt gaattgtagc
    21661 gttgtttttt gattatttac tattgcacta tacgatccat tcaatggttt attttgcgca
    21721 tcctttacgt taatggtaat cttaaaggat tgcagaagat tagcaaaagc acctgtaact
    21781 ttttttgtga ctgaaagtgt cggaagtctg tggttggtga cgattgtttg aacatcctct
    21841 gacaaagtcc cctcttgttt ttcataggtg acatgatatc ccgttctaga gttctctact
    21901 tcttccacct tatagtgggt atcacgaggc agataactga gggcagtttc ctgactattt
    21961 ttgagagaaa tctgtgcttt cccgttagtc actgttgtat tcccaaactt gccgttaatc
    22021 ggcttgccat ccttatctga aaaggtaaca ttaattgtga aagatttatt aggtgattgt
    22081 tcaccttcta ggattttctt tacggtgaga cttggaagct gtcggtaaat aactttgaag
    22141 gatggtttct ctttcgtacc tgtcttttga acttcgactg tgtatcccgg agcgtctggt
    22201 gctttcagtt cgtagtcata tcccttagct acctttgcaa aactagtatt ttcagtaaaa
    22261 ctattcgttt gaactggact agtgaccttt cgataggaat cctttatact tccatctttc
    22321 ttttggttta agtttaattc gacactaggt ggacgatttg ctgatggatt tgattttcca
    22381 tccacacctt tccactcaat ctctacagga accgtcaatg gatctgacgg cttgaaagtg
    22441 ggcttctcag aatagtcttt tattttggta cgtgaggtcc caataccata ggaataggca
    22501 acttttgccc ccttgttgga gtagagttta gtagcatcgg cttcttcggc atcatcacta
    22561 gtaagtgtct tatcacccgc aatcgcatca aatgcctctt ggctagaggt gacagtaaac
    22621 ttgagaacgt acttggcgtc atcctccaaa gtgtaactcg gattaaactt ggctgttact
    22681 tccactaatc cctgttcgtt cttcttagtt tcaatcgtaa cttgattgtc attcagttct
    22741 tgctcgttac catccttgat tttgacgaca cgaaggtgtg aagcatcacc aggtaacagc
    22801 tgcacgtact tggacaagac atctgatata gttacatggt gtacgcctag aggtagaatt
    22861 ttatctgtga tttctttgaa tttttgttgc aagtcatttt cattattggc agaaaatatt
    22921 tcgttgggga ttccagaatt ataaccactg atatatcctt taagagatgt gatactatcg
    22981 tttgaaccta tataatatct gaatttgatt gaataaaagc catctatttt tggagctatt
    23041 aaactagata tattcagcat tcctctttct aaaccagagg taaaccaata tggagtatca
    23101 atcatacgtc ccacatttgg attagaataa tagttatata ttgttctccc actattagac
    23161 tcgtaataca tattagcttc gccatctgac agcagaataa ctactttttt tgccccagcc
    23221 cttgcacttt gcaacaatct ttgagcttca gttaacccag catttatatt tgtcccagtg
    23281 ccaatgcccg cgtccatacc ataagaacga ctagagtcag caattgttaa cgaactaaca
    23341 atattttttg agctattaga atccgtgctc caagatacta aagttttagc atcatcatat
    23401 gaagagatat ttgaatacca accagctcaa tttggccaag ttccatattg ataactcaga
    23461 taatattcat tataataacg gtcattatac tgattatcaa tctttccggc aaaaccaact
    23521 atagacagac ggttttggga attagaaaga attgtatcaa tgagcccctg acgaccattc
    23581 acacctttca gtgtatgttt tagtgcttca atcctactaa tgtatcgtct actagagtaa
    23641 gaccacacat ctcgctcttc catactccct gaaagatcgg caaccaagac tacatccaag
    23701 ggttctgact gggtctccgt tcccagttta gatgtgatat ccagtgacaa ctcatactgg
    23761 tctttttgcc ctgatatcgg agtaatcgtt ttgtgcagag ttgtctgagg ttcagttatt
    23821 gaatctgcac gtaaagaatt aattggtgca cacaaaaaaa gaatagcgag aaagataact
    23881 aaactactgg taaaatattg aatcttctta aaatcatatt gaacgttcat gctatctccc
    23941 ttgctagaat atgttttaat ctgatactat ataaatctga gacttccata agataattgt
    24001 ataataatat taacttcgtg tcaattaatg tgtttgaaaa catgttatta taaattacaa
    24061 aaaagtatga ttcttctttg tttttcaact ttttctgtgg taaaatggaa aaaatagtaa
    24121 aaaatttcat aaaataaaga tgcatatatt tattctaatc gctcgaaaat ttcttttgaa
    24181 agtcttctga atttgaatta ttatattttt tcaaaattca taaaatttct caaatcatat
    24241 ttttccgaag ttttgtattc tattttatga taaaaaagga gtttttttat gacttatcca
    24301 aatctcttgg accgcttctt aacctacgtt aaggtcaaca cgcgctctga tgaacactct
    24361 actactactc caagtacaca gagtcaggtt gacttcgcaa caaatgtcct aattcctgaa
    24421 atgaaacgtg ttggactgca aaatgtttac tatctaccga atggttttgc tattggaacc
    24481 ttgccagcca acgatccgtc tttaacacgt aagattggtt ttatatcgca catggatact
    24541 gctgatttta atgctgaagg agtcaatcca caggtaattg aaaactacga tggtggtgtg
    24601 attgaactag ggaattctgg tttcaaactc gatccagccg acttcaagag tcttgaaaaa
    24661 tatccaagac aaacactcat cacaacagat ggaacaacct tgctaggtgc tgatgacaag
    24721 tcaggaattg ctgaaattat gacagccatt gaatatctaa ctgctcatcc tgaaattaag
    24781 cactgtgaga ttcgtgttgg ttttggtcca gatgaagaaa tcggtgttgg tgccaataaa
    24841 tttgatgcag aagattttga tgtggatttt gcctacactg ttgatggtgg tccactaggt
    24901 gaacttcagt acgagacttt ctcagccgct ggtgctgaat tgcatttcca aggccgtaat
    24961 gtccaccctg gtactgccaa agggcagatg gtcaatgccc ttcagctagc aattgatttt
    25021 cataatcaac ttccagaaaa tgaccgacct gagttaactg aaggttacca aggtttttac
    25081 catctaatgg atgtgacagg tagtgttgag gaggtgcgtg caagctacat cattcgtgat
    25141 tttgaaaaag atgcctttga agcgcgtaaa gcatccatgc aatctatcgc tgataagatg
    25201 aatgaagaac ttgggagcga ccgtgtcact ctcaacttga cagaccagta ctacaatatg
    25261 aaagaagtca ttgaaaaaga tatgactcca attaccattg ctaaagccgt tatggaagat
    25321 ctaggtatca cgcctattat cgaaccaatc cggggtggaa cagacggctc taagatttcc
    25381 tttatgggaa tcccaactcc gaatatcttt gcaggtggcg aaaatatgca cggacgtttt
    25441 gaatacgtta gccttcagac tatggaacgt gcagttgata ccatcattgg catcgtagct
    25501 tataaaggct aaaaagacga ggtggctcag ctacttcgcc tttcttttta ttctactggt
    25561 ttttcttgat ttccagtagt tgtagaagat tctgttgttt cattttctga agttgattca
    25621 gcaggtttag aatctcttgt attgcttggt ttgttttcgt cgctagcagt ttcaatgtta
    25681 gattctgcag ttgcgtttgg ttggttctca gcactggtgt tatcactatt tgcttcagca
    25741 tttcttgctg gacttgtttc ttcacttgcg ctaacttttg actggatttg atgattcaaa
    25801 actagaatag cttttgtcga ttcaagtaaa gctgttttgt ctttactatt agcagaaagt
    25861 tgatctaata atgcatccac cttatcaaag tccgcatcag atccattatt actttctaaa
    25921 taagagtgaa gcgacatgag aatatcgtag agtttttgat agagtacaag tgtctgagaa
    25981 tcttgctcag cattttcctt ttcttgttga agggcgctag cgatacgagt caaaacatct
    26041 tttacctgac tgtttacttc atccaagtct gcatcagcct tgtttgtggc agcttttaga
    26101 ttttctactt cttctgccaa ggattgtctg attccttctt catggatttg ttccaagagt
    26161 tgatttgcct tgttcaaaag actttctact tcttccttgc tatctgtcgc agattattgg
    26221 ttgctatcta ccatgtactc ctaaaacagg agagttataa tccaagatta caaggcctta
    26281 cagaaataag aaatccagat aagacaatgt tcgtccaaga cgctattcgc ttcgcacagc
    26341 agcacggatt caatatgctt taattttaaa gtttaggtgt caagacctct ttttagtgtg
    26401 cccaaaattt agagaagtaa tcaatcaact aacttttatt tttttcaaac tttcagtaaa
    26461 ctgacctaaa gctaactcaa tctgtctttg tagatgcttc tgctatcagc tagaagttga
    26521 tctacttttg ccaagactgc cttctcatca aaagttccag gttgatagtt ggattgcagg
    26581 gatggaatct tgtttttcaa agccgcttca tatcccttag tttgaacctt gatgtagtga
    26641 ttgtggtcgc catgaggaat cacaaaacct tctgaatctt cacttataat tcgattggca
    26701 tcaaaaacca taaccatctt cttcctcatg gtggacatgt agtgacggat tacttaatac
    26761 agaactagaa gaacttccta cctcttccgt gttagagtgt gatgggggat tgttaagaga
    26821 tgacttagga atatagtgat agtgttcccc atgtcttact atataagcat cacctatatc
    26881 tctgacaata tcattagggt taaagacata tgtggctgct aattcacctg ccgacaagtc
    26941 actctcagga atgaaatgat agtgaccacc atgtggtact attagtagat tgaaatagaa
    27001 tatgagcaaa ttgataaggg gattttaaag taatttctaa caatgattta gaaactatga
    27061 tgtgctattc taaattcaac tcactatata taaccatcat cggtagtata acgtccctgt
    27121 aattttgcta cagatacttc tgcactagct cctttatcgt ctttaccatg ttcttgtttt
    27181 tggcgattga tttcatcttt tgttcgtaca ttttctgcat gagcttgatc tttaaggtaa
    27241 acataatact ttccatctac cttaataata tatcctccct taacctaact gacaatatct
    27301 tgatctttcg gctgatagtt gggggctttc attaatggct cttcactaaa gagcgcatca
    27361 aaaggaactt taccattata gtagtgataa tgatcgccat gagaagttac ataaccttga
    27421 tctgtaatct taataacaat ttgttttgct tgaattcctt ctttttgact aacctagtct
    27481 ggagtcaaat tttcagtctt cttagtgtct ttattactgt ttacatatga aacacgattt
    27541 ttatctgtat tggcctgtta gctatgttgg ttcagagcat aaacacacag acttaaggaa
    27601 aggataacaa cagatccagc tgctatatat ttctttttaa atttcataat tacctcattt
    27661 ctataattat ttatatgatg tcttcattat taaatgatta tagaaattaa ttaaccaatt
    27721 aattaactag taaatattcc acctcttttt aagttgtatg tcaagaaatt ttatatatta
    27781 ataataaaat gaaattctcc caaagtcaga gttttatttc taacttttga gagaacttca
    27841 tttttgattc agactttttc tactgctatt ccttacgcta tgagatcaga taaattcttt
    27901 tttatcactt ctccacttgg caatcttaat tcaatcgttc catccatatt gaatataaca
    27961 ctatctaagc ctaatccgta actagctgta aatttttcta atttttcttg tacaggatct
    28021 actgctggag cttcctctaa tgctggatct aacatagggt cactccccac attcccttct
    28081 ggattcaaca ttccattatc cgttgagttt tctggtttta caggtttttc gtttggtgcc
    28141 tctggtaaag aatctgctgg tttattttct gttggttggt tctcaactgt tccagtagat
    28201 acttttccat tttcagatgg tttattttca ccatttcctt gaggtgcttc tcctgtaaaa
    28261 tctgccatat tctttttaat gacttctccc gatggtaaat ataattcaat tgttccgtcc
    28321 atattaaaca agacattttc tagcttcatc ccataacttt cagcaaattt tgctactttt
    28381 tcttgtacag gatccactgt aggaacttct tctaacgttg aattactagt actattccca
    28441 gtttcagaaa gtttttcttt ttctaccttc tcactagtct ttggttcttc taccttttca
    28501 tcaagttttg agttttcttg tgctttattc cttttaaatt gtggtagaat acttggttta
    28561 tcagtttgat tttctttttc caagataggt acttccacaa tataagtcga ttgattgtcc
    28621 aaataagcat ttgccatgaa ggttacagga attttatttc cggccgttct ggttgttcct
    28681 tggtttaatt tcggaatcgg taatttgatt tcaccaactt tatagttatt ttctaaataa
    28741 gcatttccat gaaattcatc aaacactctg actaaagcat cagttccttt aggcactgca
    28801 aattgagggt tcactcttaa ataagtatcc cctgcatgga aaggatagaa aatcgtttga
    28861 ctggccattt tgtaagctaa agaggttgga actgtaaatg taccatcata acttacttct
    28921 ggataatctt ttgaagcgat agtatactta aatgtttgtc ctggtaaata aggttgatct
    28981 aattcaaagt ttgcaatatt ccctactcct tctccaaata ctttaccaga tactttctcc
    29041 aatacttttc catctggtgt tattaatttt actagcatat tgatacctaa ttttttctcc
    29101 aattcaggcg gaaaactaaa agaaacgcgt ttttgaccat tggctagagt aaagttttga
    29161 ttattaaacg tactattttt taacaaatta acaacattcg ttaattcttc tccagtataa
    29221 actttattcc cttctttttt agcaactcct tcttcgggtt taaacagttc atagttactg
    29281 tgagaatgac caattccaac cggtttatgt tcatcaatcg gatctgcatg atggtgatct
    29341 ccatgcggat aaataatcgc atttttttct ttattcacga caatactttc acgtttgaca
    29401 ccatattgtt tcataatgcc agcaattttt tcttcgattt ttttatctaa atctttcatt
    29461 tctttggcat tacttggata atcctgttca tgagatgaca aagaatctaa tccattatga
    29521 ctagttttaa cttcctctaa atgtttttgc gcagccttaa tttgctcttc tgtcaagtcc
    29581 ttcttgaaga aataatgatt gtggtctccg tgactcatga caaaacctga ttcatcttca
    29641 gcgataatac gattagcatc aaatccgtat ccatcttctt catgtttctc atgtgaagtt
    29701 cctggattga ttggaagaga tggagaaggt gttgctagac tattgtttgg aagagtcggt
    29761 tgcccaattt gatttgattt tggaatgtaa tggaaatgat caccatgtct tacaatataa
    29821 gctgtagccg tttcttcaac gatatctttt ggattaaaaa tataaccatc agatgctgaa
    29881 gagagctcct tacttgtcgt taaagaagaa ggattgcttg aaagactgcc tagactagac
    29941 actacttcat taggttttgc atttgtagaa actgtagaac cagttccact gataggcacc
    30001 attctggcaa tcttttcttc taaggcagaa agcttgctgt aaggaataaa gtggtaatgg
    30061 tcgccatgcg gaatcgcaac tccatttggt gtacgactga taatcttagc agggtcaaag
    30121 accaggccat ctgattcact gtaacgttgg gcgctaggtg aatcatagag ttccttcaaa
    30181 agactctgga gattttcaga tttatttgct ggcttgctag ttgatccttt tgctacagat
    30241 tgcgtgttat tgtcactagc tgttgaagaa tagcttaact gactcggttg catatttttt
    30301 ccagccagat gtgctttagc tgctgctaat tcactagcag ataaatcgct tttgggaatg
    30361 tagtgatagt gacctccatg aggaacgata taagcattac ccgtatcttc gataatatca
    30421 gctggattaa agacataacc atcatttgtc gtatatcgtc cctgagacct tgctacagca
    30481 acattagagt taaccttctc attatctttg acatgttctt gtttttgacg attgatttca
    30541 tctttagttc gaacattatc agcatgagct gcatctttca ggtagacata atattttcca
    30601 tcgaccttga tgatataacc acccttgact tcattgacaa tatcagcgtc tttaagttga
    30661 tagtttggat ccttcatcaa gagttcttca ctaaagaggg catcataagg aactttccca
    30721 ttatagtaat gatagtggtc accgtgtgac gttacatagc cctgatctgt aattttgatt
    30781 acaatttgct cggcctgaat tccttctttc tggctaatct ggtctggtgt caagttttca
    30841 cttttctgac ttgactggct gccatctaca taagagacac gattattgtc cttattttcc
    30901 tgcgaacgat gctggtttag tgcataggca catagactca aggatacgat aacagctgat
    30961 ccagctgcta tatatttttt actgaatttc ataaatccct ca
//
LOCUS       DAVBDR010000020        30742 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.020, whole genome shotgun sequence.
ACCESSION   DAVBDR010000020 DAVBDR010000000
VERSION     DAVBDR010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 30742)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30742)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30742
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.020"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            16..210
                     /locus_tag="VQ540_000933"
     CDS             16..210
                     /locus_tag="VQ540_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001244258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HET2544753.1"
                     /translation="MGAEAIRRNCERGAIFSGKIKHHEDSQFKGDHYVECYAVLDNTV
                     IARDRITVPIDPLCGKDFIE"
     gene            554..1888
                     /gene="trmFO"
                     /locus_tag="VQ540_000934"
     CDS             554..1888
                     /gene="trmFO"
                     /locus_tag="VQ540_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate--tRNA-(uracil(54)-
                     C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO"
                     /protein_id="HET2544754.1"
                     /translation="MSQSYINVIGAGLAGSEAAYQIAERGIPVKLYEMRGVKSTPQHK
                     TDNFAELVCSNSLRGDALTNAVGLLKEEMRRLGSVILESAEATRVPAGGALAVDRDGF
                     SQMVTEKVANHPLIEVVRDEITELPTDVITVIATGPLTSDALAEKIHALNDGDGFYFY
                     DAAAPIIDVNTIDMSKVYLKSRYDKGEAAYLNAPMTKQEFMDFHEALVNAEEAPLNSF
                     EKEKYFEGCMPIEVMAKRGIKTMLYGPMKPVGLEYPDDYTGPRDGEFKTPYAVVQLRQ
                     DNAAGSLYNIVGFQTHLKWGEQKRIFQMIPGLENAEFVRYGVMHRNSYMDSPNLLEQT
                     YRSKKQPNLFFAGQMTGVEGYVESAASGLVAGINAARLFKEESEAIFPETTAIGSLAH
                     YITHADSKHFQPMNVNFGIIKELEGERIRDKKARYEKIAERALADLEEFLTV"
     gene            1972..2709
                     /locus_tag="VQ540_000935"
     CDS             1972..2709
                     /locus_tag="VQ540_000935"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000013002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HET2544755.1"
                     /translation="MANPKYKRILIKLSGEALAGERGVGIDIQTVQTIAKEIQEVHSL
                     GIEIALVIGGGNLWRGEPAAEAGMDRVQADYTGMLGTVMNALVMADSLQQVGVDTRVQ
                     TAIAMQQVAEPYVRGRALRHLEKGRIVIFGAGIGSPYFSTDTTAALRAAEIEADAILM
                     AKNGVDGVYNADPKKDKTAVKFEELTHRDVINKGLRIMDSTASTLSMDNDIDLVVFNM
                     NQSGNIKRVVFGENIGTTVSNNIEEKE"
     gene            2718..3275
                     /gene="frr"
                     /locus_tag="VQ540_000936"
     CDS             2718..3275
                     /gene="frr"
                     /locus_tag="VQ540_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HET2544756.1"
                     /translation="MANAIIEKAKERMTQSHQSLAREFGGIRAGRANASLLDRIHVEY
                     YGVETPLNQIASITIPEARVLLVTPFDKSSLKDIERALNASDLGITPANDGSVIRLVV
                     PALTEETRRDLAKEVKKVGENAKVAVRNIRRDAMDEAKKQEKAKEITEDELKTLEKDI
                     QKVTDDAVKHIDDMTANKEKELLEV"
     gene            3335..4189
                     /gene="cvfB"
                     /locus_tag="VQ540_000937"
     CDS             3335..4189
                     /gene="cvfB"
                     /locus_tag="VQ540_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding virulence regulatory protein CvfB"
                     /protein_id="HET2544757.1"
                     /translation="MNTNLASFIVGLIIDENDRFYFVQKDGQTYALAKEEGQHTVGDT
                     VKGFAYTDMKQKLRLTSLEVTATQDQFGWGRVTEVRKDLGVFVDTGLPDKEIVVSLDI
                     LPELKELWPKKGDQLYIRLEVDKKDRIWGLLAYQEDFQRLARPAYNNMQNQNWPAIVY
                     RLKLSGTFVYLPENNMLGFIHPSERYAEPRLGQVLDARVIGFREVDRTLNLSLKPRSF
                     EMLENDAQMILTYLESNGGFMTLNDKSSPDDIKATFGISKGQFKKALGGLMKAGKIKQ
                     DQFGTELI"
     gene            4198..4413
                     /locus_tag="VQ540_000938"
     CDS             4198..4413
                     /locus_tag="VQ540_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HET2544758.1"
                     /translation="MRKSFYTWLMTERNPKSNNPKAILADLAFEEAAFPKHTDDFDEV
                     SRFLEEHASFSFNLGDFDSIWQEYLEH"
     gene            4499..5467
                     /locus_tag="VQ540_000939"
     CDS             4499..5467
                     /locus_tag="VQ540_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HET2544759.1"
                     /translation="MKEHSIDIQLSHPDDLFHLFGSNERHLRLMEEELDVVIHARTEI
                     VQVLGEESACEEARQVIQALMALVNRGMTVGTPDVVTAISMVKNDEIDKFVALYEEEI
                     IKDNTGKPIRVKTLGQKLYVDSVKQHDVTFGIGPAGTGKTFLAVTLAVTALKRGQVKR
                     IILTRPAVEAGESLGFLPGDLKEKVDPYLRPVYDALYQILGKDQTTRLMEREIIEIAP
                     LAYMRGRTLDDAFVILDEAQNTTIMQMKMFLTRLGFHSKMIVNGDISQIDLPRNVKSG
                     LIDAQEKLKNIHQIDFVHFSAKDVVRHPVVAQIIRAYEYSTEVAHD"
     gene            5647..6147
                     /locus_tag="VQ540_000940"
     CDS             5647..6147
                     /locus_tag="VQ540_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000566985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2544760.1"
                     /translation="MIDQLSKYYSCRILTEKDIPSILSLYESNPLYFQHCPPEPNFAT
                     VKEDMLCLPEGKAKADKFFVGFWNGSDLVAVMDFVYAYPDEETVFIGLFMVDQAYQRK
                     GIGSHIVTEALAYFAKNFRKARLAYVKGNPQSQHFWEKQGFKSIGCEVKQELYTVVIA
                     EQSLED"
     gene            6150..6410
                     /locus_tag="VQ540_000941"
                     /pseudo
     CDS             6150..6410
                     /locus_tag="VQ540_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003069408.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TfoX/Sxy family protein"
     gene            complement(6777..7888)
                     /gene="ald"
                     /locus_tag="VQ540_000942"
                     /pseudo
     CDS             complement(6777..7888)
                     /gene="ald"
                     /locus_tag="VQ540_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253293.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alanine dehydrogenase"
     gene            8065..8634
                     /locus_tag="VQ540_000943"
     CDS             8065..8634
                     /locus_tag="VQ540_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2544761.1"
                     /translation="MESIFVKFAQYPSIETERLLLRPVTLDDAEAMFDYASDKGNTRY
                     TFPTNQSLEETKNNIAQFYLANPLGRWGIELKDNGKFIGTIDLHKIDPVLKKAAIGYI
                     INKKYWNQGLTTEANRAVIELAFEKIGMNKLTALHDKANPASGKVMEKSGMRFSHAEP
                     YACMDQHEKGRIVTRVHYVLTKEDYFANK"
     gene            8702..9352
                     /locus_tag="VQ540_000944"
     CDS             8702..9352
                     /locus_tag="VQ540_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000387331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HET2544762.1"
                     /translation="MEAIIEKIKEYKIIVICTGLGLLVGGFFLLKPAPQTSVKETNLQ
                     AEVAAVSKDSSTGKEVNKEEKEEPVEQDLITVDVKGAVKSPGIYDLPVGSRVNDAVQK
                     AGGLTEQADSKSLNLAQKVSDEALVYVPTKGEEAVSQQTGSGTASSTSKEKKVNLNKA
                     SLEELKQVKGLGGKRAQDIIDHREANGKFKSVDELKKVSGIGAKTIEKLKDYVTVD"
     gene            9336..11576
                     /locus_tag="VQ540_000945"
     CDS             9336..11576
                     /locus_tag="VQ540_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HET2544763.1"
                     /translation="MLQWIKNFSIPLIYLSFLLLWLYYAIFSVSYFALLGFVFLLVCL
                     FIQFPWKSAGKVLVICGVFGFWFLFQTWQQSQVSQNLVDSVERVRILPDTIKVNGDSL
                     SFRGKSDGRAFQVYYKLQSEEEKEAFQALTDLHEIGLEGKLSEPEGQRNFGGFDYQGY
                     LKTQGIYQTLNIKRIQSLQKVGSWDIGENLSSLRRKAVVWIKMHFPDPMRNYMTGLLL
                     GHLDTDFEEMNELYSSLGIIHLFALSGMQVGFFMDGFKKLLLRLGLTQEKLKWLTYPF
                     SLIYAGLTGFSASVIRSLLQKLLAQHGVKGLDNFALTVLVLFIVMPNFFLTAGGVLSC
                     AYAFILTMTSKEGEGLKAVTSESLVISLGILPILSFYFAEFQPWSILLTFVFSFLFDL
                     VFLPLLSILFVLSFLYPVIQLNFIFEWLEGIIRLVSQVASRPLVFGQPNEWLLILLLI
                     SLALVYDLRKNIKKLTVLCLLITGLFLLTKHPLENEITMLDVGQGESIFLRDVTGKTI
                     LIDVGGKAESYKKIKKWQEKMTTSNAQRSLIPYLKSRGVAKIDQLILTNTDKEHVGDL
                     SEMTKAFHVGEILVSKDSLKQKEFVAELQATQTKVRSMIVGENLPIFGSQLEVLSPRK
                     MGDGGHDDTLVLYGKFLDKQFLFTGNLEEKGEKDLLKHYPDLKVNVLKASQHGNKKSS
                     SPAFLEKLKPELTLISVGKSNRMKLPHQETLTRLEGINSKVYRTDQQGAIRFKGLDSW
                     KIESVR"
     gene            11756..11944
                     /locus_tag="VQ540_000946"
     CDS             11756..11944
                     /locus_tag="VQ540_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2544764.1"
                     /translation="MTVTKSYKYDWNTVLEYSTNYHDHQYAWIPEWSRYYSYSEYKVG
                     GGWNYARYEVINYYTGGY"
     gene            11976..12563
                     /locus_tag="VQ540_000947"
     CDS             11976..12563
                     /locus_tag="VQ540_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000939891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2544765.1"
                     /translation="MLNLTHVTLKTRQVILQDADFTFKKGRIYGLLAINGSGKTTLFR
                     AMSKLLPLSSGHIAVPPSLFYYESVEWLDGNLSGMDYLRLIKNIWKSDLNLRDEIAYW
                     EMADYISLPIRKYSLGMKQRLVIAMYFLSQAKCWLMDEITNGLDEYYRQKFFDRLAQI
                     DRQEQLVLLSSHYKEELVDICDRVVTIHQGQIEEV"
     gene            12567..13742
                     /locus_tag="VQ540_000948"
     CDS             12567..13742
                     /locus_tag="VQ540_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2544766.1"
                     /translation="MKDVSLFLLKKVFKSRLNWIILALFVSVLGVTFYLNSQTANSHS
                     LESRLESRIAANERAINENEEKLSQMSDTSSEEYQFAKNNLDVQKNLLTRKTEILTLL
                     KEGRWKEAYYLQWKDEEKNYEFVSNDPTASSGLKMGVDRERKIYQALYPLNIKAHTLE
                     FPTHGIDQIVWILEVIIPSLFVVAIIFMLTQLFAERYQNHLDTAHLYPVSKVTFAISS
                     LGVGVGYVTVLFIGICGFSFLVGSLISGFGQLDYPYPIYSLVNQEVTIGKIQDVLFPG
                     LLLAFLAFIVIVEVVYLIAYFFKQKMPVLFLSLIGIVGLLFGIQTIQPLQRIAHLIPF
                     TYLRSVEILSGRLPKQIDNVDLNWSMGMVLLPCLIIFLLLGILFIERWGSSQKKRIF"
     misc_feature    13916..14047
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            14063..14593
                     /gene="infC"
                     /locus_tag="VQ540_000949"
     CDS             14063..14593
                     /gene="infC"
                     /locus_tag="VQ540_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000848185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HET2544767.1"
                     /translation="MKTIAKQDLFINDEIRVREVRLIGLEGEQLGIKPLSEAQALADN
                     ANVDLVLIQPQAKPPVAKIMDYGKFKFEYQKKQKEQRKKQSVVTVKEVRLSPTIDKGD
                     FDTKLRNARKFLEKGNKVKVSIRFKGRMITHKEIGAKVLAEFAEATQDIAIIEQRAKM
                     DGRQMFMQLAPATDKK"
     gene            14626..14826
                     /gene="rpmI"
                     /locus_tag="VQ540_000950"
     CDS             14626..14826
                     /gene="rpmI"
                     /locus_tag="VQ540_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HET2544768.1"
                     /translation="MPKQKTHRASAKRFKRTGSGGLKRFRAYTSHRFHGKTKKQRRHL
                     RKASMVHSGDYKRIKAMLTRLK"
     gene            14878..15237
                     /gene="rplT"
                     /locus_tag="VQ540_000951"
     CDS             14878..15237
                     /gene="rplT"
                     /locus_tag="VQ540_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019786714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HET2544769.1"
                     /translation="MARVKGGVVSRKRRKRILKLAKGYYGAKHILFRTAKEQVMNSYY
                     YAYRDRRQKKRDFRKLWITRINAAARMNGLSYSQLMHGLKLAEIEVNRKMLADLAVND
                     AVAFTALADAAKAKLGK"
     gene            15295..15675
                     /locus_tag="VQ540_000952"
     CDS             15295..15675
                     /locus_tag="VQ540_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HET2544770.1"
                     /translation="MASKMLHTCLRVENLEKSIAFYQDAFGFKELRRRDFPDHAFTIV
                     YLGLEGDDYELELTYNYDHGPYVVGDGFAHIALSTPDLEALHQEHSAKGYEVTEPNGL
                     PGTTPNYYFVKDPDGYKVEVIREK"
     gene            15925..16725
                     /locus_tag="VQ540_000953"
     CDS             15925..16725
                     /locus_tag="VQ540_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HET2544771.1"
                     /translation="MNPTCKKRLGVIRLETMKVVAQEEIAPAIFELVLEGEMVEAMRA
                     GQFLHLRVPDDAHLLRRPISISSIDKANKQCHLIYRIEGAGTAIFSTLSQGDTLDVMG
                     PQGNGFDLSDLDEQNQVLLVGGGIGVPPLLEVAKELHERGVKVVTVLGFANKDAVILK
                     TELAQYGQVFVTTDDGSYGIKGNVSVVINDLDSQFDAVYSCGAPGMMKYINQTFDDHP
                     RAYLSLESRMACGMGACYACVLKVPESETVNQRVCEDGPVFRTGTVVL"
     gene            16688..17674
                     /locus_tag="VQ540_000954"
     CDS             16688..17674
                     /locus_tag="VQ540_000954"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013193458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HET2544772.1"
                     /translation="MVLFSAQEQLYYKEKIMTTNRLQVSLPGLDLKNPIIPASGCFGF
                     GQEYAKYYDLNLLGSIMIKATTLEPRFGNPTPRVAETPAGMLNAIGLQNPGLEVVLAE
                     KLPWLEREYPNLPIIANVAGFSKQEYAAVSHGISKATNVKAIELNISCPNVDHCNHGL
                     LIGQDPDLAYDVVKAAVEASEVPVYVKLTPSVTDIVTVAKAAEDAGASGLTMINTLVG
                     MRFDLKTRKPILANGTGGMSGPAVFPVALKLIRQVAQTTDLPIIGMGGVDSAEAALEM
                     YLAGASAIGVGTANFTNPYACPDIIENLPKVMDKYGISSLEELRQEVKESLR"
     gene            17716..19617
                     /locus_tag="VQ540_000955"
     CDS             17716..19617
                     /locus_tag="VQ540_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HET2544773.1"
                     /translation="MNLGEFWYNKINKNRGRRLMKKVRFIFLALLFFLASPEGAMASD
                     GTWQGKQYLKEDGSQAANEWVFDTHYQSWFYIKADANYAENEWLKQGDDYFYLKSGGY
                     MAKSEWVEDKGAFYYLDQDGKMKRNAWVGTSYVGATGAKVIEDWVYDSQYDAWFYIKA
                     DGQHAEKEWLQIKGKDYYFKSGGYLLTSQWINQAYVNASGAKVQQGWLFDKQYQSWFY
                     IKENGNYADKEWIFENGHYYYLKSGGYMAANEWIWDKESWFYLKFDGKIAEKEWVYDS
                     HSQAWYYFKSGGYMTANEWIWDKESWFYLKSDGKMAEKEWVYDSHSQAWYYFKSGGYM
                     AKNETVDGYQLGSDGKWLGGKATNENAAYYQVVPVTANVYDSDGEKLSYISQGSVVWL
                     DKDRKSDDKRLAITISGLSGYMKTEDLQALDASKDFIPYYESDGHRFYHYVAQNASIP
                     VASHLSDMEVGKKYYSADGLHFDGFKLENPFLFKDLTEATNYSAEELDKVFSLLNINN
                     SLLENKGATFKEAEEHYHINALYLLAHSALESNWGRSKIAKDKNNFFGITAYDTTPYL
                     SAKTFDDVDKGILGATKWIKENYIDRGRTFLGNKASGMNVEYASDPYWGEKIASVMMK
                     INEKLGGKD"
     gene            complement(19678..21333)
                     /gene="pavA"
                     /locus_tag="VQ540_000956"
     CDS             complement(19678..21333)
                     /gene="pavA"
                     /locus_tag="VQ540_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_094859469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rqc2 family fibronectin-binding protein PavA"
                     /protein_id="HET2544774.1"
                     /translation="MSFDGFFLHHIVEELRSELVNGRIQKINQPFEQELVLQIRSNRQ
                     SHRLLLSAHPVFGRIQLTQTTFENPAQPSTFIMVLRKYLQGALIESIEQVENDRIVEI
                     TVSNKNEIGDHIQATLIIEIMGKHSNILLVDKSSHKILEVIKHVGFSQNSYRTLLPGS
                     TYIAPPSTKSLNPFTIKDEKLFEILQTQELTAKNLQSLFQGLGRDTANELERILVSEK
                     LSAFRNFFNQETKPCLTETSFSPVPFANQVGEPLANLSDLLDTYYKDKAERDRVKQQA
                     SELIRRVENELQKNRHKLKKQEKELLATDNAEEFRQKGELLTTFLHQVPNDQDQVILD
                     NYYTNQPIMIALDKALTPNQNAQRYFKRYQKLKEAVKYLTDLIEETKATILYLESVET
                     VLNQAGLEEIAEIREELIQTGFIRRRQREKIQKRKKLEQYLASDGKTIIYVGRNNLQN
                     EELTFKMARKEELWFHAKDIPGSHVVISGNLDPSDAVKTDAAELAAYFSQGRLSNLVQ
                     VDMIEVKKLNKPTGGKPGFVTYTGQKTLRVTPDSKKIASMKKS"
     gene            21438..21935
                     /gene="ybeY"
                     /locus_tag="VQ540_000957"
     CDS             21438..21935
                     /gene="ybeY"
                     /locus_tag="VQ540_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HET2544775.1"
                     /translation="MYIEMVDETGQVSKEMLQQTQEILEFAAQKLGKEDKEMAVTFVT
                     NERSHELNLGYRDTDRPTDVISLEYKPELEIAFDEEDLLENPELAEMMSEFDAYIGEL
                     FISIDKAHEQAEEYGHSFEREMGFLAVHGFLHINGYDHYTPEEEAEMFGLQEEILTAY
                     GLTRQ"
     gene            21916..22311
                     /locus_tag="VQ540_000958"
     CDS             21916..22311
                     /locus_tag="VQ540_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000378166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HET2544776.1"
                     /translation="MDSQDNKRKWKNRDLISSLEFAITGIFTAIKEERNMRKHAVTAL
                     VVILAGFGFQVSRIEWLFLLLSIFLVVAFEIINSAIENVVDLASHYHFSMLAKNAKDM
                     AAGAVLVVSLFAALTGALIFLPRIWDLLF"
     gene            22328..23227
                     /gene="era"
                     /locus_tag="VQ540_000959"
     CDS             22328..23227
                     /gene="era"
                     /locus_tag="VQ540_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HET2544777.1"
                     /translation="MTFKSGFVAILGRPNVGKSTFLNHVMGQKIAIMSDKAQTTRNKI
                     MGIYTTDKEQIVFIDTPGIHKPKTALGDFMVESAYSTLREVDTVLFMVPADEARGKGD
                     DMIIERLKAAKVPVILVVNKIDKVHPDQLLSQIDDFRNQMDFKEIVPISALQGNNVSR
                     LVDILSENLDEGFQYFPSDQITDHPDRFLVSEMVREKVLHLTREEIPHSVAVVVDSMK
                     RDEETDKVHIRATIMVERDSQKGIIIGKGGAMLKKIGSMARRDIELMLGDKVFLETWV
                     KVKKNWRDKKLDLADFGYNEREY"
     gene            23276..24100
                     /gene="mutM"
                     /locus_tag="VQ540_000960"
     CDS             23276..24100
                     /gene="mutM"
                     /locus_tag="VQ540_000960"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001114577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HET2544778.1"
                     /translation="MPELPEVETVCRCLEKLIIGKKISSIEIRYPKMIKTDLEEFQRE
                     LPSQIIESMGRRGKYLLFYLTDKVLISHLRMEGKYFYYPDQGPERKHAHVFFHFEDGG
                     TLVYEDVRKFGTMELLVPDLLDAYFISKKLGPEPSEQDFDLQVFQSALAKSKKPIKSH
                     LLDQTLVAGLGNIYVDEVLWRAQVHPARSSQTLTAEEATAIHDQTIAVLSQAVEKGGS
                     TIRTYTNAFGEDGSMQDFHQVYDKTGQGCVRCGTIIEKIQLGGRGTHFCPNCQRRD"
     gene            24100..24705
                     /locus_tag="VQ540_000961"
     CDS             24100..24705
                     /locus_tag="VQ540_000961"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HET2544779.1"
                     /translation="MGKIIGITGGIASGKSTVTNFLRQQGFQVVDADAVVHQLQKPGG
                     RLFEALVQHFWQEIILENGELNRPLLASLIFSNPDEREWSKQIQGEIIREELATLREQ
                     LAQTEEIFFMDIPLLFEQDYSDWFAETWLVYVDRDAQVERLMKRDQLSKDEAESRLAA
                     QWPLEKKKDLASQVLDNNGNQNQLLNQVHILLEGGRQDDRD"
     gene            24692..25891
                     /locus_tag="VQ540_000962"
     CDS             24692..25891
                     /locus_tag="VQ540_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HET2544780.1"
                     /translation="MTEINWKDNLRIAWFGNFLTGASISLVVPFMPIFVENLGVGSEQ
                     VAFYAGLAISVSAISAALFSPIWGILADKYGRKPMMIRAGLAMTITMGGLAFVPNIYW
                     LIFLRLLNGVFAGFVPNATALIASQVPKEKSGSALGTLSTGVVAGTLTGPFIGGFIAE
                     LFGIRTVFLLVGSFLFLAAILTICFIKEDFQPVAKEKAIPTKELFTSVKYPYLLLNLF
                     LTSFVIQFSAQSIGPILALYVRDLGQTENLLFVSGLIVSSMGFSSMMSAGVMGKLGDK
                     VGNHRLLVVAQFYSVIIYLLCANASSPLQLGLYRFLFGLGTGALIPGVNALLSKMTPK
                     AGISRVFAFNQVFFYLGGVVGPMAGSAVAGQFGYHAVFYATSLCVAFSCLFNLIQFRT
                     LLKVKEI"
     gene            25891..26040
                     /gene="rpmG"
                     /locus_tag="VQ540_000963"
     CDS             25891..26040
                     /gene="rpmG"
                     /locus_tag="VQ540_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HET2544781.1"
                     /translation="MRVKINLKCSSCGSINYLTSKNSKTHPDKIEVLKYCPKERKVTL
                     HLESK"
     gene            26080..26313
                     /gene="secG"
                     /locus_tag="VQ540_000964"
     CDS             26080..26313
                     /gene="secG"
                     /locus_tag="VQ540_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HET2544782.1"
                     /translation="MYNLLLTILLVLSVVIVIAIFMQPTKNQSSNVFDASSGDLFERS
                     KARGFEAVMQRLTGILVFFWLAIALALTVLSSR"
     gene            26415..28769
                     /gene="rnr"
                     /locus_tag="VQ540_000965"
     CDS             26415..28769
                     /gene="rnr"
                     /locus_tag="VQ540_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HET2544783.1"
                     /translation="MKDRIKEYLQDKGKVTVNDLAQALGKDSSKDFRELIKTLSLMER
                     KHQIRFEEDGSLTLEIKKKHEITLKGIFHAHKNGFGFVSLEGEEDDLFVGKNDVNYAI
                     DGDTVEVVIKKVADRNKGTAAEAKIIDILEHSLTTVVGQIVLDQEKPKYAGYIRSKNQ
                     KISQPIYVKKPALKLEGTEVLKVFIDKYPSKKHDFFVASVLDVVGHSTDVGIDVLEVL
                     ESMDIVSEFPEAVVKEAESVPDAPSQKDMEGRLDLRDEITFTIDGADAKDLDDAVHIK
                     ALKNGNLELGVHIADVSYYVTEGSALDKEALNRATSVYVTDRVVPMLPERLSNGICSL
                     NPQVDRLTQSAIMEIDKHGRVVNYTITQTVIKTSFRMTYSDVNDILAGDEEKRKEYHK
                     IVSSIELMAKLHETLENMRVKRGALNFDTNEAKILVDKQGKPVDIVLRQRGIAERMIE
                     SFMLMANETVAEHFSKLDLPFIYRIHEEPKAEKVQKFIDYASSFGLRIYGTASEISQE
                     ALQDIMRAVEGEPYADVLSMMLLRSMQQARYSEHNHGHYGLAADYYTHFTSPIRRYPD
                     LLVHRMIRDYGRSKEIAEHFEQVIPEIATQSSNRERRAIEAEREVEAMKKAEYMEEYV
                     GEEYDAVVSSIVKFGLFVELPNTVEGLIHITNLPEFYHFNERDLTLRGEKSGITFRVG
                     QQIRIRVERADKMTGEIDFSFVPSEFDVIEKGLKQSSHSGRGRGSNRRSDKKEDKRKS
                     GRSNDKRKHSQKDKKKKGKKPFYKEVAKKGAKHGKGRGKGRRTK"
     gene            28732..29199
                     /gene="smpB"
                     /locus_tag="VQ540_000966"
     CDS             28732..29199
                     /gene="smpB"
                     /locus_tag="VQ540_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HET2544784.1"
                     /translation="MAKGEGKVVAQNKKARHDYTIVDTLEAGMVLTGTEIKSVRAARI
                     NLKDGFAQVKNGEVWLSNVHIAPYEEGNIWNQEPERRRKLLLHKKQIQKLEQETKGTG
                     MTLVPLKVYIKDGYAKLLLGLAKGKHDYDKRESIKRREQNRDIARVMKAVNQR"
     gene            29215..30075
                     /gene="tehB"
                     /locus_tag="VQ540_000967"
     CDS             29215..30075
                     /gene="tehB"
                     /locus_tag="VQ540_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase TehB"
                     /protein_id="HET2544785.1"
                     /translation="MEKLVAYKRMPLWNKQTMPEDVQQKHNTKVGTWGKITVLKGALK
                     FIELTEEGEVLAEHLFEAGADNPMAQPQAWHRVEAATDDVEWYLEFYCKPEDYFAKKY
                     NTNPVHSEVLEAMQTVKQGKALDLGCGQGRNSLFLAQQDFDVTAVDQNGLALEILQSI
                     VEQEDLDMPVGLYDINSASIEQEYDFIVSTVVLMFLQADRIPAIIQNMQEKTSVGGYN
                     LIVCAMDTEDYPCSVNFPFTFKEGELADYYKDWELVKYNENPGHLHRRDENGNRIQLR
                     FATLLAKKIK"
     gene            30148..>30742
                     /gene="coiA"
                     /locus_tag="VQ540_000968"
     CDS             30148..>30742
                     /gene="coiA"
                     /locus_tag="VQ540_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000495911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HET2544786.1"
                     /translation="MFVARDARGELVNVLEDKLEKQAYTCPACGGQLHLRQGPSVRTH
                     FAHKSLKDCDFFFENESPEHLANKESLYHWLKKETKVQLEYPLSELKQIADVFVNGNL
                     ALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
                     YVWELDKEKQVLRLKYLIYQDLRGKLHYQIKEFSYGQG"
BASE COUNT         9132 a         5689 c         7052 g         8869 t
ORIGIN      
        1 tggaaagtaa gaaatattgg agctgaggcg attagaagaa attgtgagcg tggtgctatt
       61 ttttcaggta aaataaaaca tcacgaagat tctcagttta aaggagacca ctatgttgaa
      121 tgttatgctg ttttagataa tacggttata gcaagagata gaataacagt ccctatcgat
      181 ccgttatgtg gaaaagattt tatagagtag catataattg attcttaact ggaatactct
      241 ctatctcttt acatcaagaa aatgactaaa cagggaagtt tgccttcttc cctttttttg
      301 ttatactagt agaagaaaaa aatagaaaga tttgtgggag tgaaaaagtc cgggggactt
      361 tttcagcttg agccaagaaa ttcgagagcg aggaaagtcc gggggacttt ttcagcctga
      421 gccaagaaat tcgagagcga agtaagtcca atggactttt tcagcctgag ccaagaaact
      481 cgaaagctcg taagtctgat tggctttttc aatgtgaatc ttaacttcac actcccaaag
      541 aggtattagt gtcgtgtctc aatcttatat caatgttatc ggtgctggtt tggcaggttc
      601 tgaagcagct taccaaatcg cagagcgtgg tattccagtt aaactatatg aaatgcgtgg
      661 tgtcaagtcg actccccagc ataaaacaga caattttgct gagttggttt gttccaattc
      721 tttgcgtggg gatgctttga caaatgcagt tggtcttctc aaggaagaaa tgcgtcgctt
      781 gggttctgtt atcttggaat ctgctgaggc tacacgtgtt cctgcaggtg gtgcccttgc
      841 agtggaccgt gatggtttct ctcaaatggt gaccgaaaaa gttgccaacc accccttgat
      901 tgaagtggtt cgtgatgaaa ttacagaatt gccgacagat gttattacgg ttatcgctac
      961 tggtcctttg acaagtgatg ccttggctga aaagattcat gcccttaatg acggtgatgg
     1021 tttttatttc tacgatgcgg cagcgcctat tatcgatgtc aacactatcg atatgagcaa
     1081 ggtctacctc aaatcacgtt atgataaggg agaagcggcc tacctcaatg cccctatgac
     1141 caagcaagaa tttatggatt tccatgaagc tttggtcaat gcagaagaag caccgcttaa
     1201 ttcttttgaa aaagaaaagt actttgaagg ctgtatgcct atcgaagtca tggccaaacg
     1261 tggcattaaa actatgcttt atggccctat gaagccagtc ggtcttgagt acccagacga
     1321 ctatacagga cctcgtgatg gagaatttaa aacaccttat gcggttgtgc aacttcgtca
     1381 ggacaatgca gctggtagcc tctacaatat tgttggtttc cagacccacc tcaaatgggg
     1441 agaacaaaag cgtatcttcc aaatgattcc gggtcttgaa aatgcagagt ttgtccgtta
     1501 tggtgtcatg catcgcaatt cttacatgga ttcaccaaat cttcttgagc agacttaccg
     1561 ttctaagaaa caaccaaatc tcttctttgc tggtcagatg acgggggtgg aaggctatgt
     1621 tgagtcggcg gcttcaggct tagttgcggg aattaacgca gctcgtctct tcaaggaaga
     1681 aagcgaggct attttccccg agacgacagc gattggaagc ttagctcatt acattaccca
     1741 tgccgacagc aaacatttcc aaccaatgaa tgtcaatttt gggatcatca aggagttgga
     1801 aggcgagcgt atccgtgata agaaggctcg ttatgaaaaa attgcagagc gtgcccttgc
     1861 cgacttagag gaatttttga ctgtctaatt tttttgaaag aattgctcat gatactataa
     1921 aaatcttaga aattgtgata aaataggtag gatgaaagaa ggagagtgaa aatggcgaat
     1981 cccaagtata aacgtatttt aatcaagtta tcaggtgaag cccttgccgg tgaacgtggc
     2041 gtagggattg atatccaaac agttcaaaca atcgcaaaag agattcaaga agttcatagc
     2101 ttaggtatcg aaattgccct tgttattggt ggaggaaatc tctggcgtgg agaacctgca
     2161 gcagaagcag gtatggaccg tgttcaggca gattacactg gaatgcttgg gactgttatg
     2221 aatgctcttg tgatggcaga ttcattgcaa caagttgggg ttgatacgcg tgtacaaaca
     2281 gctattgcta tgcaacaagt ggcagagcct tatgtccgtg gacgtgccct tcgtcacctt
     2341 gaaaaaggcc gtatcgttat ctttggtgct ggaattggtt caccatactt ctcgacagat
     2401 acaacagcgg cccttcgtgc agctgaaatc gaagcggatg ccatcctcat ggctaaaaat
     2461 ggtgtcgatg gtgtttacaa tgccgatcct aagaaagata agacagctgt taagtttgaa
     2521 gaattgaccc accgtgacgt tatcaataaa ggtcttcgta tcatggactc aacagcttca
     2581 accctctcaa tggacaacga cattgacttg gttgtcttca acatgaacca atcaggcaac
     2641 atcaaacgtg tcgtatttgg tgaaaatatc ggaacaacag tttcaaataa tatcgaagaa
     2701 aaggaataag aaagaatatg gctaacgcaa ttattgaaaa agctaaagag agaatgaccc
     2761 agtctcacca atcacttgct cgtgaatttg gtggtatccg tgctggtcgt gccaatgcaa
     2821 gcttgcttga ccgtatacat gtagaatact atggagttga aactcctctt aaccaaatcg
     2881 cttcaattac gattccagaa gcgcgtgttt tgttggtaac accatttgac aagtcttcat
     2941 tgaaagacat cgaacgtgcc ttgaacgctt ctgatcttgg tatcacacca gctaatgacg
     3001 gttctgtgat tcgcttggtt gtcccagctc ttacagaaga gactcgtcgt gaccttgcta
     3061 aagaagtgaa gaaggtcggc gaaaatgcta aagtggctgt ccgcaatatc cgtcgcgatg
     3121 ctatggacga agctaagaaa caagaaaaag caaaagaaat cactgaagac gaattgaaga
     3181 ctcttgaaaa agacattcaa aaagtaacag acgatgctgt taaacacatc gacgatatga
     3241 ctgccaacaa agagaaagaa cttttggaag tctaaaaata aacagaaaaa ctcagttggc
     3301 attgctggct gagttttatt cgaaagaagg aaatatgaat acaaatcttg caagttttat
     3361 cgttggactg atcatcgatg aaaacgaccg tttttacttt gtgcaaaagg atggtcaaac
     3421 ctatgctctt gctaaggaag aaggccaaca tacagtaggg gatacggtca aaggttttgc
     3481 atacacggat atgaagcaaa aactccgcct gacaagctta gaagtgactg ccactcagga
     3541 ccaatttggt tggggacgtg tcacagaggt tcgtaaggac ttgggtgtct ttgtggatac
     3601 aggccttcct gacaaggaaa tcgttgtgtc actcgatatt ctccctgagc tcaaggaact
     3661 ctggcctaag aagggcgacc aactctacat ccgtcttgaa gtggataaga aagaccgtat
     3721 ctggggtctc ttggcttatc aagaagactt ccaacgtctt gctcgtcctg cctacaacaa
     3781 catgcagaac caaaactggc cagccattgt ttaccgtctc aagctatcag gaacttttgt
     3841 ttacctacca gaaaataata tgcttggttt tattcatcct agcgagcgtt acgcagagcc
     3901 acgtttgggg caagtattag atgcgcgcgt tattggtttc cgtgaagtgg accgcacttt
     3961 gaacctctcc ctcaaaccac gctcctttga aatgttggaa aacgatgctc agatgatttt
     4021 gacttatttg gaaagcaatg gcggtttcat gaccttaaat gacaagtcat ctccagacga
     4081 catcaaggca acctttggca tttctaaagg tcagttcaag aaagctttag gtggtcttat
     4141 gaaggctggt aaaatcaagc aggaccagtt tggtacagag ttgatttagg gaggcttatg
     4201 agaaaatcat tttacacttg gctcatgacc gagcgcaatc ctaaaagtaa caatcccaaa
     4261 gcaattttgg cagacctcgc ttttgaagag gcagcttttc caaaacatac agatgatttt
     4321 gatgaggtca gtcgcttttt ggaggagcat gccagtttct cttttaacct aggagatttt
     4381 gacagcattt ggcaggaata tctagaacac tagcatttat tcattgggtt tgggctagta
     4441 atttctccat ccctctgcta taataaaaag aaataaaagg attagagagg ttctttattt
     4501 gaaggaacat tcaatagaca ttcaactgag tcatccagat gacctgtttc atctttttgg
     4561 ttccaatgaa cgccatcttc gtttgatgga agaagagctt gatgttgtga ttcatgctcg
     4621 tacggagatt gtccaggttt tgggagaaga gtctgcttgc gaggaagccc gtcaggttat
     4681 tcaagctctc atggccttgg taaatcgtgg gatgaccgtt ggtacgccag atgtagtgac
     4741 ggctattagt atggtcaaaa atgatgaaat tgacaagttt gtcgcccttt acgaagaaga
     4801 aatcatcaag gataatactg ggaagcctat ccgcgtcaaa accttaggtc aaaaacttta
     4861 tgtggacagt gtcaaacagc atgatgtgac ctttggaatt gggccagcag gtacagggaa
     4921 gaccttcctt gcagtgacct tggcagtgac tgcccttaaa cgtgggcaag tcaagcgaat
     4981 tatcctaact cgtccagcgg tggaagcggg agagagtctt ggatttcttc cgggtgatct
     5041 taaggagaag gtggatcctt accttcgtcc tgtttacgat gccttgtatc aaattcttgg
     5101 gaaagaccaa acgactcgtc tcatggagcg tgaaattatc gaaattgcgc cccttgccta
     5161 tatgcgtggc cggaccttgg atgatgcctt tgtcattctc gatgaggcgc aaaacacgac
     5221 catcatgcag atgaagatgt tcttgacgcg tttaggcttt cattctaaga tgattgtcaa
     5281 tggagatatc agtcagattg acctgccacg taatgtcaag tccggtttga ttgatgctca
     5341 agagaaactc aagaacatcc atcagattga ctttgttcat ttttcagcca aggatgtggt
     5401 tcgccatcca gttgtcgctc agattatccg agcctatgaa tattctactg aagttgcaca
     5461 cgactgattt tgaggaagtt cgcctgcaaa agaatatact tttgagagag gaaaatccag
     5521 ttgtataggc taaaggtttg agacaacgat taggcacgat ggaaagaact tttatgtggc
     5581 tgatgacgat cagtgcatct tcctgtgtca taatcacagg gcacaagaaa gtaggaattt
     5641 gaaaagatga ttgaccaact atctaagtat tacagttgta ggatactaac tgaaaaggat
     5701 attccaagta ttttatcttt atatgaaagt aatcctctgt attttcagca ttgtccacca
     5761 gagccaaatt ttgcaactgt aaaagaggac atgctttgtc tacctgaagg taaagctaag
     5821 gctgataagt tttttgttgg attttggaat ggctctgacc ttgtggctgt tatggatttt
     5881 gtctatgcat atcctgatga ggagactgtt tttattggtt tgtttatggt tgatcaagcc
     5941 tatcagagga aagggattgg tagtcatatt gtgacagaag cactagctta ttttgctaag
     6001 aactttcgaa aggcacgttt ggcttatgtt aagggaaatc cgcaatctca gcatttttgg
     6061 gaaaagcagg gctttaaatc aattggatgc gaggttaagc aagaactcta tacggttgtt
     6121 atcgctgaac agagcctaga agattagaaa tggcatcaag taagaactat ttggaatttg
     6181 ttttggaaca attatcagga ttagatgatg tgacttaccg ttccatgatt ggggagtata
     6241 ttctttactt ccgcggcaag attattggcg gcatttatga cgatcgcttt ttagttaaac
     6301 ccgtgcaagc agtcttagat aagattgacc aatcttcttt tgagtttcca tacaaaggtg
     6361 ccaaagaaat gatttgagtg gaagaacttg ataataagat gtttctataa gacctgattt
     6421 tagctatgta taaccaactg ccaacgccca aacctaaaaa gaaaaagcaa gggtgaacga
     6481 agtaaaaaag aagtctgcta aggccctgtc tttgcacggg taaaatttta tatataaaaa
     6541 gaagctggga ctaaagagct cagcttcctt tggtttatat aattgtcatt acaagacgaa
     6601 gtggttgggc gaaactctgt tgactttatt caatttagag tttcttatgc acaattgagt
     6661 ctggaacgaa agtctccagt tgcaaagtat acagtacaat aaaccaacga tgtaatagct
     6721 gatgacacaa agcacagtgg gtaggacttg cgaagtcacc cttttctttt caaaatttat
     6781 actaaatcat tgatatcagt gtagtcacga ttaagtcctt gagcaactgg taggctagtc
     6841 aagtaacctt gataagtggt cacaccttga cgcaagcctt catcttcaga gattgcttgt
     6901 gcgaatcctt tgccagccaa agcttcgata taaggaagag tgacattggt tagggcgatg
     6961 gttgaagtgc gggcaaccgc accagggata ttggcaacgg catagtggag aacaccgtgt
     7021 ttttcataga cgggttcatc gtgcgttgtc acacggtcag ctgtttcgat aacgccacct
     7081 tggtcaacag caacgtcaac gatacagagc ctggacgcat ttgtttgacc atctcatctg
     7141 tcaccaattc cggtgctttt gcaccaggga tgagaatggc tccaatcacc acatcagcat
     7201 ctctcacact tgcttcaatg ttgaatgaat tagatataat agtttgaatt tgacttccaa
     7261 agacttcttc tagaactgag agacgcttgg cactaatatc taaaatagtc acttgagcac
     7321 caagaccaag ggcgatgcgg gcagcatgtg taccgacgac accatcaccg atgatagtta
     7381 cttttccttt tggaacacct ggtacaccac caagtagaac accagagcca ccagcttgct
     7441 tagtaaggaa gtgagctccg atttgaacag ccatacgacc tgcaacctca ctcataggaa
     7501 cgaggagcgg tagttgtcct tgattgtcac gaacagtttc ataggcaatt cctgttgttt
     7561 ttgctgctaa catagcatct gctaattctg gagcagcggc catgtgcaag taggtgaaga
     7621 gaagaagatc gtcgcgcaag taaccgtatt cagaacttaa aggttctttt actttcacaa
     7681 ccaactctgc tgcccaagct tcaccagcag tagcgacaat ctcagctcct tgcttttgat
     7741 agtcagcatc agtaaagcca gaaccgagac cagcatttgt ttcgataagg acacgatgac
     7801 cacgactaac taagctatga acacctgcag gtgtgagggc gacacggttt tcgttatttt
     7861 taatttcttt tgggattccg attaacattg agataaccta cctttcaatt gacggtcttg
     7921 ttttggttgt cacattccag ttcataaatc aaaaatgtga cggtttcatt gtatatgaaa
     7981 ccgcttcaaa aatcaagaaa aacttgtcat ccaaattttt ttatgctaga ctagtgaaaa
     8041 tcaagctcta atggagggaa aagtatggaa tcaatatttg tgaaatttgc ccagtatccg
     8101 tctatagaaa cggagcgttt attgcttaga cctgtaactt tggatgatgc ggaagcaatg
     8161 tttgactatg cctcggacaa gggtaataca cgttacactt ttccaaccaa tcaaagcttg
     8221 gaagaaacca agaataacat tgctcagttc tacttggcta atcccttggg acgttggggg
     8281 attgaattaa aagataacgg caagtttatc ggaactattg acttacacaa gattgatcct
     8341 gttcttaaga aggcagctat tggctacatt atcaataaaa agtattggaa tcaaggatta
     8401 acgacagaag ccaatcgtgc tgtgattgag ctagcttttg agaagatagg gatgaataag
     8461 ttgactgccc ttcacgataa ggctaatccc gcgtcaggaa aggtcatgga gaaatcaggc
     8521 atgcgttttt cccatgcaga accatatgct tgtatggacc agcatgaaaa aggccgaatc
     8581 gtgacaagag ttcattatgt cttgaccaag gaagactatt ttgcaaataa ataagcagtt
     8641 gaaaagaaat ttttcgactg ttttttcttc ctcttacgaa taatctaaga gaggagaaaa
     8701 tatggaagca attatcgaga aaatcaaaga gtataaaatc atcgtcatct gtactggtct
     8761 gggcttgctt gtaggaggat ttttcctgct aaagccagct ccacaaacat ctgtcaaaga
     8821 gacgaatttg caggctgaag ttgcagctgt ttccaaggac tcatcgaccg gaaaggaagt
     8881 gaacaaggaa gagaaggaag aaccagttga acaagatcta atcacagtag atgtcaaagg
     8941 tgctgtcaaa tcgccaggga tttatgactt gcctgtaggt agtcgagtca atgatgctgt
     9001 tcagaaggct ggtggcttga cagagcaagc agacagcaag tcgctcaatc tagctcagaa
     9061 agttagtgat gaggctctgg tttacgttcc tactaaggga gaagaagcag ttagtcaaca
     9121 gactggttcg gggacagctt cttcaacaag caaggaaaag aaggtcaatc tcaacaaggc
     9181 cagtctggaa gaactcaagc aggtcaaggg actgggagga aaacgagctc aggacattat
     9241 tgaccatcgt gaggcaaatg gcaagttcaa gtcagtagac gagctcaaga aggtctctgg
     9301 cattggtgcc aagaccatag aaaaacttaa agactatgtt acagtggatt aagaatttct
     9361 ctattcccct aatttacctg agttttctat tactatggct ttactacgcc attttctcag
     9421 tatcctattt tgctttgttg ggttttgttt ttctgctagt ctgcctcttt atccaatttc
     9481 cttggaaatc agcaggtaaa gttctagtga tttgtggagt ctttggcttc tggtttctgt
     9541 ttcaaacttg gcaacagagt caagtgagtc aaaatttggt ggattctgtt gaaagggtac
     9601 ggattttacc agacactatt aaggttaacg gtgacagtct gtcctttcgt ggtaagtctg
     9661 atggtcgtgc tttccaagtc tattataaac tccagtccga ggaggagaaa gaagcctttc
     9721 aagctttaac tgaccttcat gagataggac tagaagggaa gctttcggag ccagaagggc
     9781 agagaaattt tggtggcttt gactaccaag gctatctgaa gactcaggga atttaccaga
     9841 cactcaatat taaaagaatc cagtcactcc aaaaggttgg cagttgggat ataggtgaaa
     9901 acctgtccag tttacgtcga aaggctgtgg tttggattaa gatgcacttc ccagacccta
     9961 tgcgcaatta catgacagga ctcttgctag gacatctgga caccgatttt gaggagatga
    10021 atgagcttta ttccagttta ggaattattc acctttttgc cttgtcaggt atgcaggtag
    10081 ggtttttcat ggacggattt aagaaactac ttttacgatt gggcttgaca caagaaaagt
    10141 tgaagtggct gacttatccc ttttccctta tctatgcggg actaactgga ttttcagcat
    10201 cggttattcg cagtctcttg caaaagctac tggctcaaca tggggttaag ggcttggata
    10261 attttgcctt gacggtgctt gtcctcttta ttgtcatgcc aaactttttc ttgacagcag
    10321 gaggagtctt gtcctgtgct tatgctttta tcctgaccat gaccagcaaa gaaggggagg
    10381 ggctcaaggc tgttactagt gaaagtctag tcatctcctt gggcatattg cccattctat
    10441 ccttctattt tgcggaattt caaccttggt ctatcctttt gacctttgtc ttttcctttc
    10501 tttttgactt ggtcttctta ccgctcttgt ctatcttatt tgtcctttcc tttctctatc
    10561 cagtcattca gctgaacttt atctttgaat ggttagaggg cattattcgc ttggtctcgc
    10621 aggtggcaag tagaccgctt gtctttggac aacccaatga atggctttta atcctattgt
    10681 taatttcttt ggctttggtc tatgatttga ggaaaaacat taaaaagcta acggtattgt
    10741 gcttattgat tacagggctc tttctcctga ccaagcatcc actggaaaat gaaatcacca
    10801 tgctggatgt ggggcaagga gaaagtattt tcctacggga tgtaactggg aaaaccattc
    10861 tcatagatgt aggtggtaag gcagaatctt ataagaaaat caaaaaatgg caagaaaaga
    10921 tgacgaccag caatgcccag cgaagcttga taccctatct caaaagtcga ggagtagcta
    10981 agattgacca gctaattttg actaacacgg acaaggagca tgttggagat ttgtcagaga
    11041 tgaccaaggc tttccatgta ggggagattc tagtatcaaa agacagtctg aaacagaagg
    11101 aatttgtggc agaactacag gcgactcaaa caaaggtgcg tagtatgata gtaggggaga
    11161 acttacccat ttttggaagt cagttagaag ttctatctcc aaggaaaatg ggagatggag
    11221 gacacgatga taccctagtt ctgtatggga aattcttgga taagcaattt ctcttcacgg
    11281 gaaatttgga ggagaaagga gagaaggact tgctgaagca ctatccagac ttgaaagtaa
    11341 atgttttgaa agctagccaa catggcaata aaaaatcatc aagtccagcc tttctagaaa
    11401 aactcaaacc agagcttact cttatctcag ttggaaagag caatcgaatg aaactccccc
    11461 atcaggaaac attgacacga ctggaaggta tcaatagcaa agtttatcga actgaccagc
    11521 aaggagctat acgttttaag gggttggata gttggaaaat cgaaagtgtt cgataggaag
    11581 gataaatgtt gtagattagt gaaataaact aaaaatttgt tgcataataa tgataaaaac
    11641 ggcataatga aaacgtattc aatattgagg atataaaatc attaaaaatc agcaaaagtt
    11701 gttttagtta gttagtttat aatctattgg tcttcttcag tccagtgtat ctgctgtgac
    11761 agtcactaaa agttacaagt atgattggaa tacggttttg gaatatagta ccaactatca
    11821 cgaccatcag tatgcttgga ttccggaatg gtctcgttat tacagctatt ctgagtataa
    11881 agttggcgga ggctggaact acgctcgtta tgaggtcata aactactata ctggaggtta
    11941 ttaatcctta aagagtgaga aaaggagggc tggatatgtt aaatcttact catgttacct
    12001 taaaaacgcg acaagtcatc ttgcaagatg cggattttac ctttaaaaag ggtaggattt
    12061 atggccttct tgctatcaat ggctcgggaa agacgacact attccgagct atgagcaagt
    12121 tgcttcccct tagtagtgga cacatcgcag ttcctccttc tttgttttat tatgagagcg
    12181 ttgaatggct ggatggaaac ttaagtggga tggactacct tcgtctcata aaaaacatct
    12241 ggaagtcaga cctaaacttg agagatgaaa tcgcctactg ggaaatggct gactatatca
    12301 gtcttcccat ccgcaagtat tccttaggga tgaagcaacg cttggtgatt gctatgtatt
    12361 ttctcagtca ggccaaatgc tggctcatgg atgagattac aaatggctta gacgagtatt
    12421 atcgacagaa gttttttgat aggctagcac aaatcgatag acaagaacag ctggttcttt
    12481 taagttccca ctataaggaa gagttggttg atatctgcga tagagtagta accattcatc
    12541 aggggcagat agaagaggtt tagtttatga aagatgttag tctattttta ttgaaaaaag
    12601 ttttcaaaag tcgtttaaac tggattatct tagctttatt tgtatctgta ctcggtgtta
    12661 ccttttattt aaatagtcag actgcaaact cacacagctt ggagagcagg ttggaaagtc
    12721 gcattgcagc caacgagagg gctatcaatg aaaatgaaga gaaactctcc caaatgtctg
    12781 ataccagctc ggaggaatac cagtttgcta aaaataattt agacgtgcaa aaaaatcttt
    12841 tgacgcgaaa gacagaaatt ctaactttac taaaagaagg gcgctggaaa gaagcctact
    12901 atctgcagtg gaaagatgaa gagaagaatt atgaatttgt atcaaatgac ccgactgcta
    12961 gctctggctt aaaaatgggg gttgaccgcg aacggaagat ttaccaagcc ctgtatccct
    13021 tgaacataaa agcacatact ttggagtttc cgacccacgg gattgatcag attgtctgga
    13081 ttttagaggt tatcatccca agcttgtttg tggttgcgat tatttttatg ctaacacaac
    13141 tatttgcaga aagatatcaa aatcatctgg acacagctca cttatatcct gtttcaaaag
    13201 tgacatttgc aatatcctct cttggagttg gagtgggata tgtaactgtg ctgtttatcg
    13261 gaatctgtgg cttttctttt ctagtgggaa gtctgataag tggttttgga cagttagatt
    13321 atccctaccc aatttatagc ttagtgaatc aagaagtaac tattgggaaa atacaagatg
    13381 tattatttcc tggcttgctc ttagctttct tagcctttat cgtcattgtg gaagttgtgt
    13441 acttgattgc ttactttttc aagcaaaaaa tgcctgtcct ctttctttca ctcattggga
    13501 ttgttggctt attgtttggc atccaaacaa ttcagcctct tcaaaggatt gcacatctga
    13561 ttccctttac ttacttgcgt tcagtggaga ttttatctgg aagattacct aagcagattg
    13621 ataatgtcga tctaaattgg agcatgggaa tggtcttact tccttgcctg attatctttt
    13681 tgctattggg aattctattt attgaaagat ggggaagttc acagaaaaaa agaatttttt
    13741 aatagattct agctttccta taggtaggga aaataagtaa aaactaacat agagagggaa
    13801 tcaacttgat tctctctttt tgattcgaaa accaaaccaa aatacaaaca caaacttttc
    13861 aaaaaataac tttttatctt gacaagagct agaaaacttg gtatcatata aaagttgaga
    13921 aaagcagaag tgagagcttc tcgccttgtg acattaagtt gcctggccct acggatgaaa
    13981 agtttcgaag aaacgctatc ataacgtgcg ggcttgtata tttacgagtc cgctattgtt
    14041 tttctctaat aaaacaaaag aggtgaaaac catagcaaag caagacttat tcatcaatga
    14101 tgagattcgt gtacgtgaag ttcgcttgat tggtcttgaa ggagaacagc taggcatcaa
    14161 gccactcagt gaagcgcaag ctttggctga taacgctaat gttgacctag tattgattca
    14221 accccaagcc aaaccgcctg ttgcaaaaat tatggactac ggtaagttca aatttgagta
    14281 ccagaagaag caaaaagaac aacgtaaaaa acaaagcgtt gttactgtga aagaagttcg
    14341 tctaagtcca actattgaca agggtgactt tgatacaaaa cttcgtaatg cacgtaagtt
    14401 ccttgaaaaa ggaaataaag ttaaggtatc tattcgcttt aagggtcgta tgattaccca
    14461 taaagagatt ggtgcaaaag ttttagccga gtttgctgaa gcaactcaag atattgccat
    14521 catcgaacaa cgtgctaaaa tggatggacg tcaaatgttc atgcaattgg cgccagcgac
    14581 tgacaaaaaa taattgtcag aaagttaaat aaaggagaaa aaattatgcc aaaacaaaaa
    14641 acacaccgcg catcagctaa acgtttcaaa cgtacaggtt ctggtggact taaacgtttc
    14701 cgtgcttaca cttctcaccg tttccacgga aaaactaaga aacaacgtcg tcatcttcgt
    14761 aaagcatcta tggtgcattc aggagattac aaacgtatca aagcaatgct tactcgcttg
    14821 aaataatagc ttgactgtaa gtaaacaatt ctaggaaata tttggaggaa ataaaacatg
    14881 gcacgtgtta aaggtggcgt tgtatcacgc aaacgtcgta aacgtattct taaattagca
    14941 aaaggttact atggagctaa acacatcttg ttccgtactg caaaagaaca agtaatgaac
    15001 tcttactact atgcataccg tgaccgtcgt cagaaaaaac gtgacttccg caaattgtgg
    15061 atcactcgta tcaatgcggc agctcgtatg aacggacttt catactcaca attgatgcat
    15121 ggtttgaaat tggctgagat cgaagttaac cgtaaaatgc ttgctgactt ggctgttaac
    15181 gatgcagtag ctttcacagc tcttgcagat gcagctaaag caaaacttgg taaataacaa
    15241 ctgatgagac tggaacagga ttgtccagtc tttttaaaaa taaaggagaa aaatatggct
    15301 tcaaaaatgc tacacacttg cttacgagta gaaaatcttg aaaaatcaat cgcattttat
    15361 caagatgctt ttggttttaa agaattgcgt cgcagagatt ttccagacca tgccttcacg
    15421 attgtctatc taggtcttga gggtgatgac tatgagttgg agttgactta taactacgat
    15481 cacggtccgt atgtggttgg tgatgggttt gcccatatcg ccctcagtac acctgatctt
    15541 gaggcacttc atcaagaaca cagtgcaaaa ggctatgaag tgactgagcc aaatggtcta
    15601 ccaggaacta caccaaacta ttactttgtc aaagaccctg atggatataa ggtcgaagtc
    15661 attcgtgaaa aataatttcg tgcaagttaa gtagaatatt cgttttttac ttgacttttt
    15721 ttagctgaaa gagtatacta ataaaaattc aacctttaag gggagtccag agagactcac
    15781 aaggtgtcag ataaaagaat agtgcaattt tctagaggag actttttgag tgtgctctct
    15841 tgtgttgtac gattttaact gaggccttgc actagcaagg tcttttcttt atctggtccc
    15901 cttaaaattt aaggaggaaa agttatgaat cccacatgta agaagcgttt gggtgtcatt
    15961 cggttggaaa ccatgaaggt ggttgcacaa gaggaaatcg cgccagcaat ctttgaatta
    16021 gtcctagaag gagaaatggt tgaagccatg cgagcaggcc aatttcttca tctgcgtgta
    16081 ccagacgatg cccatctttt acgtcgtcct atttcaattt cgtctattga caaggcaaac
    16141 aagcagtgtc acctcattta tcggattgag ggagctggga ctgcaatttt ttcaacctta
    16201 agtcagggag acactcttga tgtgatgggg cctcagggaa atggttttga cttgtctgac
    16261 cttgatgagc agaatcaggt tctccttgtt ggtggtggga ttggtgttcc acccttgctt
    16321 gaggtggcca aggaattgca tgaacgtgga gtgaaagtag tgacagtcct cggttttgct
    16381 aataaggatg ctgttatttt gaaaacggaa ttggctcagt atggtcaggt ctttgtaacg
    16441 acagatgatg gttcttatgg catcaaggga aatgtttccg ttgttatcaa tgatttagat
    16501 agtcagtttg atgctgttta ctcgtgtggg gctccaggaa tgatgaagta tatcaatcaa
    16561 acctttgatg atcacccaag agcctattta tctctggaat ctcgtatggc ttgtgggatg
    16621 ggagcttgct atgcctgtgt tctaaaagta ccagaaagcg agacggtcaa ccaacgcgtc
    16681 tgtgaagatg gtcctgtttt ccgcacagga acagttgtat tataaggaga aaattatgac
    16741 tacaaatcga ttacaagtgt ctctacctgg tttggatttg aaaaatccga ttattccagc
    16801 atcaggttgt tttggctttg gacaagagta tgccaagtac tatgatttaa accttttagg
    16861 ttctattatg atcaaggcga caacccttga accacgtttt gggaacccaa ctccaagagt
    16921 agcagagacg cctgctggta tgctcaatgc aattggcttg caaaatcctg gtttagaggt
    16981 tgttttggct gaaaagctac cttggctgga aagagaatat ccaaatcttc ctattattgc
    17041 caatgtagct ggtttttcaa aacaagagta tgcagctgtt tctcatggga tttccaaggc
    17101 aactaatgta aaagctatcg agctcaatat ttcttgtccc aatgttgacc actgtaatca
    17161 tggacttttg attggtcaag atccagattt ggcttatgat gtggtgaaag cagctgtgga
    17221 agcctcagaa gtgccagttt atgtcaaatt aaccccgagt gtgaccgata tcgttactgt
    17281 cgcaaaagct gcagaagatg cgggagcaag tggcttgacc atgatcaata ctctggttgg
    17341 aatgcgcttt gacctcaaaa ccagaaaacc aatcttggcc aatggaacag gtggaatgtc
    17401 aggtccagca gtctttccag tagccctcaa actcatccgc caagtagccc aaacaacaga
    17461 cctgcctatc attggaatgg ggggagtgga ttcggctgaa gctgccctag aaatgtatct
    17521 ggctggggca tctgctatcg gagttggaac agctaacttt accaatcctt atgcctgccc
    17581 tgacatcatc gaaaatttac caaaagtcat ggataaatac ggtattagca gtctggaaga
    17641 actccgtcag gaagtaaaag agtctctgag gtaaactgca atcaatctgt tcttgatttt
    17701 ttattagttt gtaatatgaa tttaggagaa ttttggtaca ataaaataaa taagaacaga
    17761 ggaagaaggt taatgaagaa agtaagattt atttttttag ctctgctatt tttcttagct
    17821 agtccagagg gtgcaatggc tagtgatggt acttggcaag gaaaacagta tctgaaagaa
    17881 gatggcagtc aagcagcgaa tgagtgggtt tttgatactc attatcaatc ttggttctat
    17941 ataaaagcag atgctaacta tgctgaaaat gaatggctaa agcaaggtga cgactatttt
    18001 tacctcaaat ctggtggcta tatggccaaa tcagaatggg tagaagacaa gggagccttt
    18061 tattatcttg accaagatgg aaagatgaaa agaaatgctt gggtaggaac ttcctatgtt
    18121 ggtgcaacag gtgccaaagt aatagaagac tgggtctatg attctcaata cgatgcttgg
    18181 ttttatatca aagcagatgg acagcacgca gagaaagaat ggctccaaat taaagggaag
    18241 gactattatt tcaaatccgg tggttatcta ctaacaagtc agtggattaa tcaagcttat
    18301 gtgaatgcta gtggtgccaa agtacagcaa ggttggcttt ttgacaaaca ataccaatct
    18361 tggttttaca taaaagaaaa tggaaactat gctgataaag aatggatttt cgagaatggt
    18421 cactattatt atctaaaatc tggtggctac atggcagcca atgaatggat ttgggataag
    18481 gaatcttggt tttatctcaa atttgatggg aaaatagctg aaaaagaatg ggtctacgat
    18541 tctcatagtc aagcctggta ctacttcaaa tccggtggtt acatgacagc caatgaatgg
    18601 atttgggata aggaatcttg gttttacctc aagtctgatg gcaaaatggc tgaaaaagaa
    18661 tgggtctacg attctcatag tcaagcctgg tactacttca aatctggtgg ttacatggcg
    18721 aaaaatgaga cagtagatgg ttatcagctt ggaagcgatg gtaaatggct tggaggaaaa
    18781 gctacaaatg aaaatgctgc ttactatcaa gtagtgcctg ttacagccaa tgtttatgat
    18841 tcagatggtg aaaagctttc ctatatatcg caaggtagtg tcgtatggct agataaggat
    18901 agaaaaagtg atgacaagcg cttggctatt actatttctg gtttgtcagg ctatatgaaa
    18961 acagaagatt tacaagcgct agatgctagt aaggacttta tcccttatta tgagagtgat
    19021 ggccaccgtt tttatcacta tgtggctcag aatgctagta tcccagtagc ttctcatctt
    19081 tctgatatgg aagtaggcaa gaaatattat tcggcagatg gcctgcattt tgatggtttt
    19141 aagcttgaga atcccttcct tttcaaagat ttaacagagg ctacaaacta cagtgctgaa
    19201 gaattggata aggtatttag tttgctaaac attaacaata gccttttgga gaacaagggc
    19261 gctactttta aggaagccga agaacattac catatcaatg ctctttatct ccttgcccat
    19321 agtgccctag aaagtaactg gggaagaagt aaaattgcca aagataagaa taatttcttt
    19381 ggcattacag cctatgatac gaccccttac ctttctgcta agacatttga tgatgtggat
    19441 aagggaattt taggtgcaac caagtggatt aaggaaaatt atatcgatag gggaagaact
    19501 ttccttggaa acaaggcttc tggtatgaat gtggaatatg cttcagaccc ttattggggc
    19561 gaaaaaattg ctagtgtgat gatgaaaatc aatgagaagc taggtggcaa agattagtac
    19621 tataagtgaa tatgatttga gtgaatagta agttaaaaat cctgatttca agtaaaatca
    19681 ggattttttc atggatgcaa tttttttgga gtctggtgtg acgcggaggg tcttttgtcc
    19741 tgtgtaagtg acaaagccgg gttttccacc agttggttta ttgagttttt tgacttcaat
    19801 catatctacc tgcaccagat tcgacaggcg cccttgagag aagtaggcag ctaactctgc
    19861 tgcgtctgtc ttgactgcat cagatgggtc aagatttcct gagatgacaa catggcttcc
    19921 aggaatgtcc ttagcatgga accaaagttc ctccttgcgg gccattttaa aggtcaattc
    19981 ctcattttga agattgtttc gtccgacata gatgatggtt ttgccatcgc ttgctagata
    20041 ttgttctagt tttttgcgtt tctggatttt ctcccgttgt cttctgcgga taaaacctgt
    20101 ttgaatcaat tcttcacgga tttcagcgat ttcttccagt ccagcttggt tgaggacggt
    20161 ttctacactt tccagataga gaatagtggc tttggtttct tcaatcaaat cagtcaagta
    20221 tttgacagct tctttgagtt tctgataccg tttaaaatag cgttgggcat tctggttggg
    20281 agtcagagcc ttatcaagcg caatcatgat aggttggttg gtatagtagt tgtctaggat
    20341 aacctggtct tggtcgttag gcacttggtg gaggaaggtt gtcagcaatt ctcctttttg
    20401 acgaaattct tcagcgttgt ctgtcgccag taactctttt tcctgttttt tgagtttgtg
    20461 tcggtttttc tgaagttcat tttcaacacg acgaatcagt tcactggcct gctgtttgac
    20521 gcggtcgcgc tcagccttat ccttatagta ggtgtccaac aaatcagaaa gatttgcaag
    20581 aggctctccc acctgatttg caaaaggaac tggactgaag gaagtctcag tcaagcatgg
    20641 cttggtttct tgattgaaaa aatttcggaa agcggaaagt ttttcactaa ccagtatcct
    20701 ttccaattca tttgccgtat cgcgtcccag accttgaaag aggctttgaa gattttttgc
    20761 tgttagttct tgggtttgca ggatttcaaa gagcttttca tccttgatag taaaaggatt
    20821 gagagatttt gtacttggcg gagcgatata ggtcgatcct ggaagtaagg tgcggtagct
    20881 attttgtgaa aagccgacgt gtttgataac ttcgaggatt ttatgactgc ttttatcgac
    20941 cagtagaata ttactgtgtt tccccataat ttcgataatc aaggtagcct ggatatggtc
    21001 tccaatctcg tttttattgg aaactgtaat ttccacaata cggtcatttt ccacttgctc
    21061 aatcgactca atcagggccc cctgcaaata ctttctcaaa accatgataa aggtagaagg
    21121 ttgggctgga ttttcaaaag tcgtttgggt cagctgaatg cgtccaaaaa ctggatgggc
    21181 agaaaggagc aggcgatggc tttggcgatt gctgcggatt tgcaagacca actcttgttc
    21241 aaaaggctga ttgattttct ggatgcgacc attcactaat tcgcttcgca attcctcaac
    21301 tatgtggtgt aaaaaaaatc cgtcaaatga catcgttctc tccttgtgat tgtattccat
    21361 agtattatat caaaaaggta gaataaaatc atggaaatgt ggtataataa agccaagtaa
    21421 agagaaacga gaagcacatg tatattgaaa tggtagatga aactggtcaa gtttcaaaag
    21481 aaatgttgca acaaacccaa gaaattttgg aatttgcagc ccaaaaatta ggaaaagaag
    21541 acaaggagat ggcagtcact tttgtgacca atgagcgtag tcatgaactt aatctggggt
    21601 accgtgacac cgaccgtccg acagatgtca tcagccttga gtataaacca gaattggaaa
    21661 ttgcctttga cgaagaggat ttgcttgaaa atccagaatt ggcagagatg atgtctgagt
    21721 ttgatgccta tattggggaa ttgttcatct ctatcgataa ggctcatgag caggccgaag
    21781 aatatggtca cagctttgag cgtgagatgg gcttcttggc agtacacggc tttttacata
    21841 ttaacggcta tgatcactat actccggaag aagaagcgga gatgttcggt ttacaagaag
    21901 aaattttgac agcctatgga ctcacaagac aataaacgaa aatggaaaaa tcgtgacctg
    21961 atatccagtt tagaatttgc catcacaggg atttttactg ctatcaagga agaacgcaat
    22021 atgcgaaaac atgcagtgac ggctctagtg gtcatccttg caggttttgg ttttcaggtg
    22081 tcacgaatcg aatggctctt tctcctattg agcattttct tggtggtagc ctttgaaatt
    22141 atcaattctg ctatcgaaaa tgtggtggat ttggccagtc actatcactt ttccatgctg
    22201 gctaaaaatg ccaaggatat ggcggctggc gcggtattag tggtttctct ttttgcagcc
    22261 ttaacaggcg cattgatttt tctcccacga atctgggatt tattatttta aacagtaaga
    22321 ggaaattatg acttttaaat caggctttgt agccatttta ggacgtccca atgttgggaa
    22381 gtcaaccttt ttaaatcacg ttatggggca aaagattgcc atcatgagtg acaaggcgca
    22441 gacaacgcgc aataaaatca tgggaattta cacgactgat aaggagcaaa ttgtctttat
    22501 cgacacacca gggattcaca aacctaaaac agctctcgga gatttcatgg ttgagtctgc
    22561 ctacagtacc cttcgcgaag tggacactgt tcttttcatg gtgcctgctg atgaagcgcg
    22621 tggtaagggg gacgatatga ttatcgagcg tctcaaggct gccaaggttc ctgtgatttt
    22681 ggtggtgaat aaaatcgata aggtccatcc agaccagctc ttgtctcaga ttgatgactt
    22741 ccgtaatcaa atggacttta aggaaattgt tccaatctca gcccttcagg gaaataacgt
    22801 gtctcgtcta gtggatattt tgagtgaaaa tctggatgaa ggtttccaat atttcccgtc
    22861 tgatcaaatc acagaccatc cagaccgttt cttagtttca gaaatggttc gcgagaaagt
    22921 cttgcaccta actcgtgaag agattccgca ttctgtagca gtagttgttg actctatgaa
    22981 acgagacgaa gagacagaca aggttcacat ccgtgcaacc atcatggtcg agcgcgatag
    23041 ccaaaaaggg attatcatcg gtaaaggtgg cgctatgctt aagaaaatcg gtagcatggc
    23101 ccgtcgtgat atcgaactca tgctaggaga caaggtcttc ctagaaacct gggtcaaggt
    23161 caagaaaaac tggcgcgata aaaagctaga tttggctgac tttggctata atgaaagaga
    23221 atactaagta gaggtgggct catgcctgct tcttgttttt acagaaggag gacttatgcc
    23281 tgaattacct gaggttgaaa ccgtttgtcg ttgcttagaa aaattgatta taggaaagaa
    23341 gatttcgagt atagaaattc gctaccccaa gatgattaag acggatttgg aagagtttca
    23401 aagggaattg cctagtcaga ttatcgagtc aatgggacgt cgtggaaaat atttgctttt
    23461 ttatctgaca gacaaggttt tgatttccca tttgcggatg gagggcaagt atttttacta
    23521 tccagaccaa ggacctgaac gcaagcatgc ccatgttttc tttcattttg aagatggtgg
    23581 cacgcttgtt tatgaggatg ttcgcaagtt tggaaccatg gaactcttgg tgcctgacct
    23641 tttagacgcc tactttattt ctaaaaaatt aggtcctgaa ccaagcgaac aagactttga
    23701 tttacaggtc tttcaatctg cccttgccaa gtccaaaaag cctatcaaat cccatctcct
    23761 agaccagacc ttggtagctg gacttggcaa tatctatgtg gatgaggttc tctggcgagc
    23821 tcaggttcat ccagctagat cttcccagac tttgacagca gaagaagcga cagctattca
    23881 tgaccaaacc attgctgttt tgagccaggc tgttgaaaaa ggcggttcca ccattcggac
    23941 ctataccaat gcctttgggg aagatggaag catgcaggat tttcatcagg tctatgataa
    24001 gactggtcaa ggatgtgtac gctgtggtac catcattgag aaaattcaac taggtggacg
    24061 tggaacccac ttttgtccaa actgtcaaag gagggactga tgggaaaaat catcggaatc
    24121 actgggggaa ttgcctctgg taagtcaact gtgacaaatt ttctaagaca gcaaggcttt
    24181 caagtagtgg atgccgacgc agtcgtccac caactacaga aacctggtgg tcgtctgttt
    24241 gaggctctag tacagcactt ttggcaagaa atcattcttg aaaacggaga actcaatcgc
    24301 cctctcctag ctagtctcat cttttcaaat cctgatgaac gagaatggtc taagcaaatt
    24361 caaggggaga ttatccgtga ggaactggct actttgagag aacagttggc tcagacagaa
    24421 gagattttct tcatggatat tcccctactt tttgagcagg actacagcga ttggtttgct
    24481 gagacttggt tggtctatgt ggaccgagat gcccaagtag aacgcttaat gaaaagggac
    24541 cagttgtcca aagatgaagc tgagtctcgt ctggcagccc agtggccttt agaaaaaaag
    24601 aaagatttgg ccagccaggt tcttgataat aatggcaatc agaaccagct tcttaatcaa
    24661 gtgcatatcc ttcttgaggg aggtaggcaa gatgacagag attaactgga aggataatct
    24721 gcgcattgcc tggtttggta attttctgac aggagccagt atttctttgg ttgtaccttt
    24781 tatgcctatc ttcgtggaaa atctaggtgt agggagtgag caagtcgctt tttatgcagg
    24841 cttagcaatt tctgtctctg ctatttccgc ggcgctcttt tctcctattt ggggtattct
    24901 tgctgacaaa tacggccgaa aacccatgat gattcgggca ggtcttgcta tgactatcac
    24961 tatgggaggc ttggcctttg tcccaaatat ctattggtta atctttcttc gtttactaaa
    25021 cggtgtattt gcaggttttg ttcctaatgc aacggcactg atagccagtc aggttccaaa
    25081 ggagaaatca ggctctgcct taggtacttt gtctacaggc gtagttgcag gtactctaac
    25141 tggtcccttt attggtggct ttatcgcaga attatttggc attcgtacag ttttcttact
    25201 ggttggtagt tttctatttt tagctgctat tttgactatt tgctttatca aggaagattt
    25261 tcaaccagta gccaaggaaa aggctattcc aacaaaggaa ttatttacct cggttaaata
    25321 tccctatctt ttgctcaatc tctttttaac cagttttgtc atccaatttt cagctcaatc
    25381 gattggccct attttggctc tttatgtacg cgatttaggg cagacagaga atcttctttt
    25441 tgtctctggt ttgattgtgt ccagtatggg cttttccagc atgatgagtg caggagtcat
    25501 gggcaagcta ggtgacaagg tgggcaatca tcgtctcttg gttgtcgccc agttttattc
    25561 agtcatcatc tatctcctct gtgccaatgc ctctagcccc cttcaactag gactctatcg
    25621 tttcctcttt ggattgggaa ccggtgcctt gattcccggg gttaatgccc tactcagcaa
    25681 aatgactccc aaagccggca tttcgagggt ctttgccttc aatcaggtat tcttttatct
    25741 gggaggtgtt gttggtccca tggcaggttc tgcagtagca ggtcaatttg gctaccatgc
    25801 tgtcttttat gcgacgagcc tttgtgttgc ctttagttgt ctctttaacc tgattcaatt
    25861 tcgaacatta ttaaaagtaa aggaaatcta gtgcgagtaa aaattaatct caaatgctcc
    25921 tcttgtggca gtatcaatta cctaaccagt aaaaattcaa aaacccatcc agacaagatt
    25981 gaggttttaa agtattgtcc caaggaaaga aaagtaaccc tacatcttga atctaagtag
    26041 attttatggt aaaataatag ggattttaag gagtttgata tgtataacct attattaacc
    26101 attttattag tattatctgt tgtgattgtg attgcaattt tcatgcaacc aaccaaaaac
    26161 caatccagca atgtatttga tgccagttca ggtgatttgt ttgaacgtag taaagctcgc
    26221 ggttttgaag ctgtaatgca gcgtttgaca gggattttag tctttttctg gctagccatt
    26281 gccttagcat tgacggtatt atcaagtaga taagaaaata atgggcagga ctaggtcttt
    26341 gcctcttttt atttttaaag gatgtttgag aaggttttac agtaaaagaa aattaaaaaa
    26401 tctagaaaga aaatatgaaa gatagaataa aagaatattt acaagacaag ggaaaggtga
    26461 ctgttaatga tttggctcag gctttgggaa aagacagttc caaggatttt cgtgagttga
    26521 ttaaaacctt gtccttaatg gaaagaaagc accaaattcg ttttgaagaa gatggtagtc
    26581 tgacattaga aattaagaaa aaacatgaga ttaccctcaa ggggattttt catgcccata
    26641 aaaatggctt tggctttgtt agtctggaag gcgaggagga cgaccttttt gtagggaaaa
    26701 atgatgtcaa ctatgctatt gatggtgata ccgtcgaggt agtgattaag aaagtcgctg
    26761 accgcaataa gggaacagca gcagaagcca aaattattga tatcctagaa cacagtttga
    26821 caacagttgt cgggcaaatc gttctggatc aggaaaaacc taagtatgct ggctatattc
    26881 gttcaaaaaa tcagaaaatc agtcaaccga tttatgttaa gaaaccagcc ctaaaattag
    26941 aaggaacaga agttctcaaa gtctttatcg ataaataccc aagcaagaaa catgatttct
    27001 ttgtcgcgag tgttctcgat gtagtgggac actcaacgga tgtcggaatt gatgttcttg
    27061 aggtcttgga atcaatggac attgtatccg agtttccaga agctgttgtt aaggaagcag
    27121 aaagtgtgcc tgatgctccg tctcaaaagg atatggaagg tcgtctggat ctaagagatg
    27181 aaattacctt taccattgac ggtgcggatg ccaaggactt ggacgatgca gtgcatatca
    27241 aggctctgaa aaatggcaat ctggagcttg gggttcacat cgcagatgtt tcttattatg
    27301 tgaccgaggg gtctgccctt gacaaggaag cccttaaccg tgcgacttct gtttacgtga
    27361 cagaccgagt ggtgccaatg cttccagaac gactatcaaa tggcatctgc tctctcaatc
    27421 cccaagttga ccgcctgacc cagtctgcta ttatggagat tgataaacat ggtcgtgtgg
    27481 tcaactatac cattacacaa acagttatca agaccagttt tcgtatgacc tatagcgatg
    27541 tcaatgatat cctagctggc gatgaagaaa agagaaaaga atatcataaa attgtatcaa
    27601 gtatcgaact catggccaag cttcatgaaa ctttagaaaa catgcgtgtg aaacgtggag
    27661 ctctcaattt tgataccaat gaagcgaaga ttttagtgga taaacaaggt aagcctgttg
    27721 atatcgttct tcggcagcgt ggtattgccg agcggatgat tgagtctttt atgttgatgg
    27781 ctaatgaaac agttgccgaa catttcagca agttggattt gccttttatc tatcgaattc
    27841 acgaggagcc taaggctgaa aaggttcaga agtttattga ttatgcttcg agttttggct
    27901 tgcgcattta tggaactgcc agtgagatta gtcaggaggc acttcaagac atcatgcgtg
    27961 ctgttgaggg agaaccttat gcagatgtat tgtccatgat gcttcttcgc tctatgcagc
    28021 aggctcgtta ttcggagcac aatcacggcc actatggact agctgctgac tattatactc
    28081 actttaccag tccaattcgt cgttatccag accttcttgt tcaccgtatg attcgggatt
    28141 acggccgttc taaggaaata gcagagcatt ttgaacaagt gattccagag attgcgaccc
    28201 agtcttccaa ccgtgaacgt cgtgccatag aagctgagcg tgaagtcgaa gccatgaaaa
    28261 aggctgagta tatggaagaa tacgtgggtg aagagtatga tgcagttgta tcaagtattg
    28321 tcaaattcgg tctctttgtc gaattgccaa acacagttga aggcttgatt cacatcacta
    28381 atctacctga attttatcat ttcaatgagc gtgatttgac tcttcgtgga gaaaaatcag
    28441 gtatcacttt ccgagtgggt cagcagatcc gtatccgtgt tgaaagagcg gataaaatga
    28501 ctggagagat tgatttttca ttcgtaccta gtgagtttga tgtgattgaa aaaggcttga
    28561 aacagtctag tcatagtggc agagggcgtg gttcaaatcg tcgttcggat aagaaggaag
    28621 acaagagaaa atcaggacgc tcaaatgata agcgtaagca ttcacaaaaa gacaagaaga
    28681 aaaaaggaaa gaaacctttt tacaaggaag tagctaagaa aggagccaag catggcaaag
    28741 ggcgagggaa aggtcgtcgc acaaaataaa aaggcacgcc acgactatac aatcgtagat
    28801 acgctagagg cagggatggt cctgactgga actgaaatca agagtgtacg agctgctcga
    28861 attaatctca aggatggctt tgctcaagtg aaaaatggag aagtttggct gagcaatgtt
    28921 catatcgcgc cttacgaaga gggcaatatc tggaaccagg aaccagaacg tcgtcgtaaa
    28981 ctcctgctcc ataaaaagca aattcaaaaa ttggaacaag agaccaaagg gacaggaatg
    29041 accttagttc cccttaaggt ctatataaaa gatggctacg ctaagcttct tttaggactt
    29101 gccaaaggga agcatgacta tgacaaacgg gagtctatca aacgtcgtga gcaaaatcga
    29161 gatatcgcgc gtgtgatgaa agctgttaat cagcgataaa aagaggaatt gaaaatggaa
    29221 aaattagttg cctataaacg catgcctttg tggaataaac aaacaatgcc tgaagatgtt
    29281 cagcaaaagc acaatacaaa agttgggact tgggggaaaa ttactgtctt gaagggagct
    29341 ctcaagttta ttgaattgac agaagaaggg gaagttctag ctgaacacct ctttgaagca
    29401 ggggcagaca atccaatggc ccaacctcaa gcctggcacc gagtggaagc tgccacagat
    29461 gatgtggaat ggtacttgga attttattgt aaacctgagg attattttgc taaaaaatac
    29521 aataccaatc ctgttcattc agaggtccta gaggccatgc agacagtgaa acaagggaaa
    29581 gctttggatt tgggttgtgg tcaggggcgt aattctcttt ttctagccca gcaagatttt
    29641 gatgtgacgg ctgtagatca aaatggacta gctcttgaaa tcttgcaaag cattgtggag
    29701 caggaagatt tggacatgcc tgttggcctt tacgatatca attcagctag cattgaacaa
    29761 gaatatgatt ttatcgtttc aacagttgtt ctcatgtttc tacaagcgga ccgcattcca
    29821 gctattattc aaaatatgca ggagaaaacc agtgttggtg gttacaacct tatcgtttgt
    29881 gccatggaca cggaggatta tccttgctcg gttaatttcc cattcacctt taaagaagga
    29941 gaactggcag actattacaa ggattgggaa ttggttaagt acaatgaaaa tccaggccat
    30001 ttgcaccgtc gcgatgagaa tggcaatcgt attcaactac gctttgcgac cttactagct
    30061 aagaaaatca agtaaacaca catgaagatt aggaattttc ctgatctttt ttctttttta
    30121 cgaatgatat agaaaaggag ggaattcatg tttgttgcga gagatgctag gggagaattg
    30181 gtaaatgtgt tagaggataa acttgagaag caagcataca cctgcccagc ttgtggaggc
    30241 cagctccatt tgcgtcaagg accaagtgta cggacgcatt ttgcccataa atccttaaaa
    30301 gactgtgatt ttttctttga aaatgaaagt ccagaacacc tggccaataa ggaatccctc
    30361 tatcactggt tgaaaaaaga gacaaaggtt caattagagt acccgctttc agaacttaaa
    30421 cagattgcgg atgtatttgt aaatggcaat ctagctctag aagttcagtg tagtcccttg
    30481 cctcagaaag tccttaaaga gcgaagtgag ggatatcgta gtcagggtta ccaagtactg
    30541 tggttgctgg gtcaaaaact gtggctcaag gagcgtttga ctcgtctaca gcaaggtttt
    30601 ctttatttca gtcaaaacat gggcttttat gtttgggaat tagacaagga aaaacaagtt
    30661 ttaagactca aatacctgat ttaccaggat ctccgcggta aactccatta tcaaatcaag
    30721 gaattttcct atggtcaagg ta
//
LOCUS       DAVBDR010000021        30073 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.021, whole genome shotgun sequence.
ACCESSION   DAVBDR010000021 DAVBDR010000000
VERSION     DAVBDR010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 30073)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30073)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30073
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.021"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            51..1100
                     /locus_tag="VQ540_000969"
     CDS             51..1100
                     /locus_tag="VQ540_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="HET2544787.1"
                     /translation="MVELGISTFGEITELEGTGQTYSHAERIRQLVAEIELADKVGLD
                     VYGIGEHHRADFAVSAPEIVLAAGAVNTKKIRLTSAVSILSSMDPIRLFQQYATIDAL
                     SNGRAEIMAGRGSFTESFPLFGYDLKDYDSLFDEKLDLLQLVNEKTKLDWQGRLTQTI
                     AGKEVYPRPVQDKLPLWIATGGHVESTVKIAQAGLPIVYAIIGGNPRYFKKLIQAYRE
                     IGSEAVHADKDLKVGAHSWGWIAEDGEQAVKDYFHPTKQVVDAISKDRPHWQELRYEQ
                     YLEQVGSNGAMFVGNPDQVAEKLIRMIEDLGLDRFMLHLPLGSMPHDQVLRAIELFGT
                     QVAPKVRAYFAMKEA"
     gene            complement(1200..5042)
                     /gene="spuA"
                     /locus_tag="VQ540_000970"
     CDS             complement(1200..5042)
                     /gene="spuA"
                     /locus_tag="VQ540_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored pullulanase SpuA"
                     /protein_id="HET2544788.1"
                     /translation="MRKTPSHTEKKMVYSIRSLKNGTGSVLIGASLVLLAMATPTISS
                     DESTPTTNEPNNRNTTTLAQPLTDTAAGSGKNESDISSPGNANASLEKTEEKPAASPA
                     DPAPQTGQDRSSEPTTSTSPVTTETKAEEPIEDNYFRIHVKKLPEENKDAQGLWTWDD
                     VEKPSENWPNGALSFKDAKKDDYGYYLDVKLKGEQAKKISFLINNTAGKNLTGDKSVE
                     KLVPKMNEAWLDQDYKVFSYEPQPAGTVRVNYYRTDGNYDKKSLWYWGDVKNPSSAQW
                     PDGTDFTATGKYGRYIDIPLNEAAREFGFLLLDESKQGDDVKIRKENYKFTDLKNHSQ
                     IFLKDDDESIYTNPYYVHDIRMTGAQHVGTSSIESSFSTLVGAKKEDILKHSNITNHL
                     GNKVTITDVAIDEAGKKVTYSGDFSDTKHPYTVSYNSDQFTTKTSWRLKDETYSYDGK
                     LGADLKEEGKQVDLTLWSPSADKVSVVVYDKNDPDKVVGTVALEKGERGTWKQTLDST
                     NKLGITDFTGYYYQYQIERQGKTVLALDPYAKSLAAWNSDDSKIDDAHKVAKAAFVDP
                     AKLGPQDLTYGKIHNFKTREDAVIYEAHVRDFTSDPAIAKDLTKPFGTFEAFIEKLDY
                     LKDLGVTHIQLLPVLSYYFVNELKNHERLSDYASSNSNYNWGYDPQNYFSLTGMYSSD
                     PKNPEKRIAEFKNLINEIHKRGMGAILDVVYNHTAKVDLFEDLEPNYYHFMDADGTPR
                     TSFGGGRLGTTHHMTKRLLIDSIKYLVDTYKVDGFRFDMMGDHDAASIEEAYKAARAL
                     NPNLIMLGEGWRTYAGDENMPTKAADQDWMKHTDTVAVFSDDIRNNLKSGYPNEGQPA
                     FITGGKRDVNTIFKNLIAQPTNFEADSPGDVIQYIAAHDNLTLFDIIAQSIKKDPSKA
                     ENYAEIHRRLRLGNLMVLTAQGTPFIHSGQEYGRTKQFRDPAYKTPVAEDKVPNKSHL
                     LRDKDGNPFDYPYFIHDSYDSSDAVNKFDWTKATDGKAYPENVKSRDYMKGLIALRQS
                     TDAFRLKSLQDIKDRVHLITVPGQNGVEKEDVVIGYQITAPNGDIYAVFVNADEKARE
                     FNLGTAFAHLRNAEVLADENQAGSVGIANPKGLEWTEKGLKLNALTATVLRVSQNGTS
                     HESTAEEKPDSTPSKPEHQNEASHPEHQDPAPEARPDSTKPDTKVADAENKPSQATAD
                     SQAEQPAQEAQASSVKEAVRNESVENSSKKNIPATPDRQAELPNTGIKNENKLLFAGI
                     SLLALLGLGFLLKNKKEN"
     gene            5459..5872
                     /gene="rpsL"
                     /locus_tag="VQ540_000971"
     CDS             5459..5872
                     /gene="rpsL"
                     /locus_tag="VQ540_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HET2544789.1"
                     /translation="MPTINQLVRKPRKSKVEKSKSPALNVGYNSHKKVQTNVSSPQKR
                     GVATRVGTMTPKKPNSALRKFARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQGRSKYGTKRPKA"
     gene            5892..6362
                     /gene="rpsG"
                     /locus_tag="VQ540_000972"
     CDS             5892..6362
                     /gene="rpsG"
                     /locus_tag="VQ540_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HET2544790.1"
                     /translation="MSRKNRAPKRDVLPDPLYNSQLVTRLINRVMLDGKRGTAASIVY
                     GAFEQIKEATGNDALEVFETAMENIMPVLEVRARRVGGSNYQVPVEVRPERRTTLGLR
                     WLVTIARLRGEHTMQDRLAKEILDAANNTGAAVKKREDTHRMAEANRAFAHFRW"
     gene            6787..8868
                     /gene="fusA"
                     /locus_tag="VQ540_000973"
     CDS             6787..8868
                     /gene="fusA"
                     /locus_tag="VQ540_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HET2544791.1"
                     /translation="MAREFSLEKTRNIGIMAHVDAGKTTTTERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWNNHRVNIIDTPGHVDFTIEVQRSLRVLDGA
                     VTVLDSQSGVEPQTETVWRQATEYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGSEDDFRGIIDLIKMKAEIYTNDLGTDILEEDIPAEYLDQAQEYREKLIEAV
                     AETDEELMMKYLEGEEITNEELKAGIRKATINVEFFPVLCGSAFKNKGVQLMLDAVID
                     YLPSPLDIPAIKGINPDTDAEEIRPASDEEPFAALAFKIMTDPFVGRLTFFRVYSGVL
                     QSGSYVLNTSKGKRERIGRILQMHANSRQEIDTVYSGDIAAAVGLKDTTTGDSLTDEK
                     AKIILESINVPEPVIQLMVEPKSKADQDKMGIALQKLAEEDPTFRVETNVETGETVIS
                     GMGELHLDVLVDRMRREFKVEANVGAPQVSYRETFRASTQARGFFKRQSGGKGQFGDV
                     WIEFTPNEEGKGFEFENAIVGGVVPREFIPAVEKGLVESMANGVLAGYPMVDVKAKLY
                     DGSYHDVDSSETAFKIAASLSLKEAAKSAQPAILEPMMLVTITVPEENLGDVMGHVTA
                     RRGRVDGMEAHGNSQIVRAYVPLAEMFGYATVLRSASQGRGTFMMVFDHYEDVPKSVQ
                     EEIIKKNKGED"
     gene            8972..13363
                     /locus_tag="VQ540_000974"
     CDS             8972..13363
                     /locus_tag="VQ540_000974"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HET2544792.1"
                     /translation="MSNSFEILMNQLGMPAEMRQAPALAQANIERVVVHKISKVWEFH
                     FVFSNILPIEIFLELKKGLSEEFSKTGNKAVFEIKARSQEFSNQLLQSYYREAFSEGP
                     CASQGFKSLYQNLQVRAEGNQLFIEGSEAIDKEHFKKNHLPNLAKQLEKFGFPTFNCQ
                     VEKNDVLTQEQEEAFHAENEQIVQAANEEALRAMEQLEQMAPPPAEEKPAFDFQAKKA
                     AAKPKLDKAEITPMIEVTTEENRLVFEGVVFDVEQKVTRTGRVLINFKMTDYTSSFSM
                     QKWVKNEEEAQKFDLIKKNSWLRVRGNVEMNNFTRDLTMNVQDLQEVVHYERKDLMPE
                     GERRVEFHAHTNMSTMDALPEVEEIVATAAKWGHKAVAITDHGNVQSFPHGYKAAKKA
                     GIQLIYGMEANIVEDRVPIVYNEVEMDLSEATYVVFDVETTGLSAIYNDLIQVAASKM
                     YKGNVIAEFDEFINPGHPLSAFTTELTGITDDHVKNAKPLEQVLQEFQEFCKDTVLVA
                     HNATFDVGFMNANYERHDLPKISQPVIDTLEFARNLYPEYKRHGLGPLTKRFGVALEH
                     HHMANYDAEATGRLLFIFIKEVAEKHGVTDLARLNIDLISPDSYKKARIKHATIYVKN
                     QVGLKNIFKLVSLSNTKYFEGVPRIPRTVLDAHREGLILGSACSEGEVFDVVVSQGVD
                     AAVEVAKYYDFIEVMPPAIYAPLIAKEQVKDMEELQTIIKSLIEVGDRLGKPVLATGN
                     VHYIEPEEEIYREIIVRSLGQGAMINRTIGHGEHAQPAPLPKAHFRTTNEMLDEFAFL
                     GEELARKLVIENTNALAEIFESVEVVKGDLYTPFIDKAEETVAELTYKKAFEIYGNPL
                     PDIVDLRIEKELTSILGNGFAVIYLASQMLVQRSNERGYLVGSRGSVGSSFVATMIGI
                     TEVNPLSPHYVCGQCQYSEFITDGSYGSGFDMPHKDCPNCGHKLSKNGQDIPFETFLG
                     FDGDKVPDIDLNFSGEDQPSAHLDVRDIFGEEYAFRAGTVGTVAAKTAYGFVKGYERD
                     YGKFYRDAEVERLAQGAAGVKRTTGQHPGGIVVIPNYMDVYDFTPVQYPADDVTAEWQ
                     TTHFNFHDIDENVLKLDVLGHDDPTMIRKLQDLSGIDPNKIPMDDEGVMALFSGTDVL
                     GVTPEQIGTPTGMLGIPEFGTNFVRGMVDETHPTTFAELLQLSGLSHGTDVWLGNAQD
                     LIKQGIADLSTVIGCRDDIMVYLMHAGLEPKMAFTIMERVRKGLWLKISEEERNGYIE
                     AMKANKVPEWYIESCGKIKYMFPKAHAAAYVMMALRVAYFKVHHPIYYYCAYFSIRAK
                     AFDIKTMGAGLEVIKRRMEEISEKRKNNEASNVEIDLYTTLEIVNEMWERGFKFGKLD
                     LYRSQATEFLIDGDTLIPPFVAMDGLGENVAKQLVRAREEGEFLSKTELRKRGGLSST
                     LVEKMDEMGILGNMPEDNQLSLFDELF"
     gene            13465..13728
                     /locus_tag="VQ540_000975"
     CDS             13465..13728
                     /locus_tag="VQ540_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HET2544793.1"
                     /translation="MSKMSISIRLDSEVKEQAQQVFSNLGMDMTTAINIFLRQAIQYQ
                     GLPFDVRLDENRKLLQALTDLDQNRNMSQSFESVSDLMEDLRA"
     gene            13721..13999
                     /locus_tag="VQ540_000976"
     CDS             13721..13999
                     /locus_tag="VQ540_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013904578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system YafQ family
                     toxin"
                     /protein_id="HET2544794.1"
                     /translation="MLKIRYHKQFKKDFKLAMKRGLKAELLEEVLNFLVQEKEHPARY
                     RDHSLTASKHFQGVRECHTQPDWLLVYKVDKSELILNLLRTGSHSDLF"
     gene            14020..14172
                     /locus_tag="VQ540_000977"
     CDS             14020..14172
                     /locus_tag="VQ540_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2544795.1"
                     /translation="MKLRIFAEDKPAKKVFEYQLELADRTILLSTALLSGAIALAGIF
                     SALKEK"
     gene            14194..15435
                     /locus_tag="VQ540_000978"
     CDS             14194..15435
                     /locus_tag="VQ540_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000243957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HET2544796.1"
                     /translation="MVLPNFKENLGKYAKLLVANGINVQPGHTLALSIDVEQRELAHL
                     IVKEAYALGAHEVIVQWTDDVINREKFLHAPMERLDNVPEYKIAEMNYLLENKASRLG
                     VRSSDPGALNGVDADKLSASAKAMGLAMKPMRIATQSNKVSWTVAAAAGLEWAKKVFP
                     NAASDEEAVDFLWDQIFKTCRVYEADPVKAWEEHAAILKSKADMLNKEQFSALHYTAP
                     GTDLTLGLPKNHVWESAGAVNAQGEEFLPNMPTEEVFTAPDFRRADGYVTSTKPLSYN
                     GNIIEGIKVTFKDGQIVDITAEKGDQVMKDLVFKNAGARALGECALVPDPSPISQSGI
                     TFFNTLFDENASNHLAIGAAYATSVVDGAEMSEEELEAAGLNRSDVHVDFMIGSNQMD
                     IDGIREDGTRVPLFRNGNWAN"
     gene            15445..15675
                     /locus_tag="VQ540_000979"
     CDS             15445..15675
                     /locus_tag="VQ540_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000901571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HET2544797.1"
                     /translation="MLGSMFVGLLVGFLAGAMTNRGERMGCFGKMFLGWIGAFLGHLL
                     FGTWGPVLSGTAIIPAILGAMIVLAIFWRRGS"
     gene            15898..16620
                     /locus_tag="VQ540_000980"
     CDS             15898..16620
                     /locus_tag="VQ540_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HET2544798.1"
                     /translation="MRLDKFLVACAVGSRTEVKNLLKAGRVTVNGKKEKSAKLQIDEK
                     IDEIRFDGQVLEYEEFVYYMMNKPKGVISATEDPKHRTVLDLLDDLARSKEVFPVGRL
                     DIDTHGLLLLTNNGQLAHVLLSPKRHVDKTYQAQVKGIMTQEDVETFIKGIPLKDFTC
                     QPARLEILSTDAEKNQSQIRVTIAEGKFHQIKRMVGYCGKEVVDLQRLTMGTLVLDEN
                     LERGEWRRLTKEELEILRANII"
     gene            16837..18171
                     /gene="pepC"
                     /locus_tag="VQ540_000981"
     CDS             16837..18171
                     /gene="pepC"
                     /locus_tag="VQ540_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000991632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase C"
                     /protein_id="HET2544799.1"
                     /translation="MNAIQESFTDKLFANYEANVKYQAIENAASHNGIFAALECRQSH
                     VDNTPVFSLDLTKDKVTNQKASGRCWMFAALNTFRHKLISQYKLENFELSQAHTFFWD
                     KYEKSNWFLEQVIATSDQELTSRKVSFLLQTPQQDGGQWDMVVSLFEKYGVVPKSVYP
                     ESVSSSSSRELNAILNKLLRQDAQILRDLLVSGADQATVQAKKEDLLQEIFNFLAMSL
                     GLPPRKFDFAYRDKDNNYKSEKGITPQEFYKKYVNLPLEDYVSVINAPTADKPYGKSY
                     TVEMLGNVVGSRAVRYINVPMERLKELAIAQMQAGETVWFGSDVGQLSNRKAGILATD
                     VYDFESSMDIKLTQDKAGRLDYSESLMTHAMVLTGVDLDENGKSTKWKVENSWGDKVG
                     TDGYFVASDAWMDEYTYQIVVRKELLTAEEQAAYGAEPIVLAPWDPMGALAE"
     gene            complement(18227..19138)
                     /locus_tag="VQ540_000982"
     CDS             complement(18227..19138)
                     /locus_tag="VQ540_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HET2544800.1"
                     /translation="MTEKLQLTKSDRKKVWWRSTFLQGSWNFERMQNLGWAYTLIPAI
                     KKLYTKKEDQIAALERHLEFFNTHPYVAAPVMGVTLALEEERANGVEIDDAAIQGVKI
                     GMMGPLAGIGDPVFWFTVRPILGSLGASLALTGNILGPLLFFVAWNLIRMSFLWYVQE
                     IGYKAGSEITKDMSGGILQDITKGASILGMFILAVLVQRWVNIKFAFDVSKVQLDEKA
                     YIHWDKLPEGSKGIQEAFAQVGQGLSQTPEKVTTFQQNLDMLIPGLSGLLLTLLCMYL
                     LKKKVSPITIILALFAVGIVAHVLHIM"
     gene            complement(19162..19965)
                     /locus_tag="VQ540_000983"
     CDS             complement(19162..19965)
                     /locus_tag="VQ540_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HET2544801.1"
                     /translation="MSIISMVLVVVVAFFAGLEGILDQFQFHQPLVACTLIGLVTGHL
                     EAGIILGGSLQMIALGWSNIGAAIAPDAALASVAAAIIMVLGGDFTKTGIGVAQAVAI
                     PLAVAGLFLTMIVRTISVGLVHTADAAAKKGDFGAVERAHFIALLFQGLRIALPAALL
                     LMVPTETVQSILSAMPDWLKDGMAIGGGMVVAVGYAMVINMMATREVWPFFALGFVLA
                     AVSDITLIGFGAIGVAIALIYLHLSKTGGNGGGGAATSNDPIGDILEDY"
     gene            complement(19993..20982)
                     /gene="manX"
                     /locus_tag="VQ540_000984"
     CDS             complement(19993..20982)
                     /gene="manX"
                     /locus_tag="VQ540_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HET2544802.1"
                     /translation="MSIGIIIASHGEFAAGIHQSGSMIFGEQEKVQVVTFMPNEGPDD
                     LYAKFNNAVAAFDAEDEVLVLADLWSGSPFNQASRVMGENPERKFAIITGLNLPMLIQ
                     AYTERLMDAAAGVEKVAANIIKEAKDGIKALPEELNPVEEVASAAAAPVAQTAIPEGT
                     VIGDGKLKINLARLDTRLLHGQVATAWTPDSKANRIIVASDNVAKDDLRKELIKQAAP
                     GNVKANVVPIQKLIEISKDPRFGETHALILFETPQDALRAIEGGVPIKTLNVGSMAHS
                     TGKTLVNTVLSMDKEDVATFEKMRDLGVEFDVRKVPNDSKKDLFDLINKANVK"
     gene            complement(21215..22234)
                     /gene="adhP"
                     /locus_tag="VQ540_000985"
     CDS             complement(21215..22234)
                     /gene="adhP"
                     /locus_tag="VQ540_000985"
                     /EC_number="1.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase AdhP"
                     /protein_id="HET2544803.1"
                     /translation="MKAVVVNPESTGVAIEEKVLRPLETGEALVEVEYCGVCHTDLHV
                     AHGDFGQVPGRVLGHEGIGIVKEIAPDVKSLKVGDRVSVAWFFEGCGTCEYCTTGRET
                     LCRTVKNAGYSVDGGMAEQCIVTADYAVKVPDGLDPAQASSITCAGVTTYKAIKEAKV
                     EPGQWVVLYGAGGLGNLAVQYAKKVFNAHVIAVDINNDKLTLAKEVGADIVINGLEVE
                     DVAGLIKEKTDGGAHSAVVTAVSKVAFNQAVDSIRAGGRVVAVGLPSEMMELSIVKTV
                     LDGIQVIGSLVGTRKDLEEAFQFGAEGLVVPVVQKRPVEDAVAIFDEMEKGQIQGRMV
                     LDFTH"
     gene            complement(22573..23385)
                     /locus_tag="VQ540_000986"
     CDS             complement(22573..23385)
                     /locus_tag="VQ540_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HET2544804.1"
                     /translation="MTKKIIAVDLDGTLLNSDSQISDFTKRTIKKVAEKGHQVIITTG
                     RPYRMSKDFYRELGLDTPMINFNGSLTHLPDQVWDFEKCLTVDKKYLLDMVQRSEDIQ
                     ADFIAGEYRKKFYITNPNEEIANPKLFGVEAFQPEDQFQPELVTKDPNCILLQTRASD
                     KYALAKEMNAFYQHQLSINTWGGPLNILECTPKGVNKAFALDYLLKIMNRDKKDLIAF
                     GDEHNDTEMLAFAGKGYAMKNANPELLPYADEQISLTNDQDGVAKTLQDLFL"
     gene            23575..24993
                     /locus_tag="VQ540_000987"
     CDS             23575..24993
                     /locus_tag="VQ540_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HET2544805.1"
                     /translation="MDKLFKLKENGTDVRTEVLAGLTTFFAMSYILFVNPQILSQTGM
                     PAQGVFLATIIGAVAGTLMMAFYANLPYAQAPGMGLNAFFTFTVVFGLGYSWQEALAM
                     VFICGIISLIITLTNVRKMIIESIPNALRSAISAGIGVFLAYVGIKNAGLLKFTIDPG
                     NYTVVGEGADKAQATIAANSSAVPGLVSFNNPAVLVALAGLAITIFFVIKGIKGGIIL
                     SILTTTVLAIAVGLVDLSSIDFANNHVGAAFEDLKTIFGAALGSEGLGALVSDTARLP
                     ETLMAILAFSLTDIFDTIGTLIGTGEKVGIVATNGENHQSAKLDKALYSDLIGTTVGA
                     IAGTSNVTTYVESAAGIGAGGRTGLTALVVAICFAISSFFSPLLAIVPTAATAPILII
                     VGIMMLGSLKNIHWDDMSEAVPAFFTSIFMGFSYSITQGIAVGFLTYTLTKLVKGQVK
                     DVHAMIWILDALFILNYISMAL"
     gene            25046..25753
                     /locus_tag="VQ540_000988"
     CDS             25046..25753
                     /locus_tag="VQ540_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET2544806.1"
                     /translation="MKEKNMWKELLNRAGWILVFLLAVLLYQVPLVVTSILTLKEVAL
                     LQSGLIVTGLSIVVLALFIMGARKTKLASFNFSFFRAKDLARLGLSYLVIVGSNILGS
                     ILLQLSNETTTANQSQINDMVQNSSLISSFFLLALLAPICEEILCRGIVPKKIFRGKE
                     NLGFVVGTIVFALLHQPSNLPSLLIYGGMSTVLSWTAYKTQRLEMSILLHMIVNGIAF
                     CLLALVVIMSRTLGISV"
     gene            25848..26822
                     /gene="folP"
                     /locus_tag="VQ540_000989"
     CDS             25848..26822
                     /gene="folP"
                     /locus_tag="VQ540_000989"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HET2544807.1"
                     /translation="MMKILEGVTDMSSKANHAKTVICGIINVTPDSFSDGGQFFALEQ
                     ALQQARKLIAEGASMLDIGGESTRPGSSYVEIEEEIQRVVPVIKAIRKESDVLISIDT
                     WKSQVAEAALAAGANLVNDITGLMGDEKMAHVVAKAGAKVVIMFNPVMARPQHPSSLI
                     FPHFGFGQTFTEKELADFETLPIEDLMVAFFERALARAAEAGITPENILLDPGIGFGL
                     TKKENLLLLRDLDKLHQKGYPIFLGVSRKRFVINILEESGFEVNPETELGFRNRDTAS
                     AHVTSIAARQGVEVVRVHDVASHRMAVEIASAIRLADEAENLDLKQYK"
     gene            26824..28146
                     /locus_tag="VQ540_000990"
     CDS             26824..28146
                     /locus_tag="VQ540_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000658404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HET2544808.1"
                     /translation="MKEIENNQWIANYRTDQPHFGLERMVELLALRGNPHLKLKVLHI
                     GGTNGKGSTIAFLKKMLEKLGLRVGVFSSPYLIHYTDQISINGESISEARLEALMADY
                     QSLLEGEAVANLQGTTEFEIITALAYDYFASEQVDVAIMEVGMGGLLDSTNVCQPILT
                     GITTIGLDHVALLGDTLEAIAEQKAGIIKQGIPLVTGRIAPEALTVIDRIAEGKDAPR
                     LAYGTDYQVRHQESVVTGEVFDYTSAVRQGRFQTSLLGLYQIENAGMAIALLDTFCQE
                     DGRELASNDFLGQALEETSWPGRLEIVSRDPLMILDGAHNPHAIKALLVTLQERFADY
                     HKEILFTCIKTKALEDMLDLLGAMPDTELTLTHFADSRATDESVLKEAAKSRNLSYQD
                     WHDFLEQNLTDKKEEKQTVRIVTGSLYFLSQVRAYLMERKNENGYTKD"
     gene            28127..28681
                     /gene="folE"
                     /locus_tag="VQ540_000991"
     CDS             28127..28681
                     /gene="folE"
                     /locus_tag="VQ540_000991"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HET2544809.1"
                     /translation="MDTQKIEAAVKMIIEAVGENANREGLQETPARVARMYQEIFSGL
                     GQTAEEHLSKSFEIIDDNMVVEKDIFFHTMCEHHFLPFYGRAHIAYIPDGRVAGLSKL
                     ARTVEVYSKKPQIQERLNIEVADALMDYLGAKGAFVVIEAEHMCMSMRGVRKPGTATL
                     TTVARGLFETDKDLRDQAYRLMGL"
     gene            28724..29536
                     /gene="folK"
                     /locus_tag="VQ540_000992"
     CDS             28724..29536
                     /gene="folK"
                     /locus_tag="VQ540_000992"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HET2544810.1"
                     /translation="MDQLQIKDLEMFAYHGLFPSEKELGQKFVVSAILSYDMTKAATD
                     LDLTASVHYGELCQQWTTWFQETSEDLIETVAYKLVERTFEFYPLVQEMKLELKKPWA
                     PVHLSLDTCSVTIHRRKQRAFIALGSNMGDKQANLKQAIDKLRARGIYILKESSVLAT
                     EPWGGVEQDSFANQVVEVETWLPAQDLLETLLAIESELGRVREVHWGPRLIDLDLLFV
                     EDQILYTDDLILPHPYIAERLFVLESLQEIAPHFIHPTLKQPIRNLYDALKK"
     gene            complement(29581..29898)
                     /locus_tag="VQ540_000993"
     CDS             complement(29581..29898)
                     /locus_tag="VQ540_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HET2544811.1"
                     /translation="MAFTNTHMRSASFGIVTSLPDDIIDSFWYIIDHFLKNVFELEEE
                     LEFQLLNNQGKITFHFSSQHLPTAIDFDFNHPFDPRYPPRVLVLDMYGRETILLPEEN
                     DLF"
BASE COUNT         8526 a         5841 c         7006 g         8700 t
ORIGIN      
        1 ttagaataat ttttcaaatt gaaggacaga gatagacaag gagaatcaca atggtagaat
       61 tgggaatttc aacatttggg gaaataacgg agcttgaagg gactggacaa acttacagtc
      121 atgctgaacg cattcgccag ttggtggcag agattgagct ggctgacaag gttggtttgg
      181 acgtatatgg gattggcgag caccatcggg cggattttgc agtatcagcc ccagagattg
      241 tcctggccgc tggggcagtc aataccaaga aaatccgttt gaccagtgca gtcagcattc
      301 tgtcaagcat ggatccgatt cgtttgttcc aacagtatgc cactatcgat gctttgtcaa
      361 atggacgagc ggagattatg gctggaaggg gctctttcac ggaatctttc cctctgtttg
      421 gttatgactt gaaagactac gactctcttt ttgatgagaa attagacttg cttcagttag
      481 tcaatgaaaa gaccaagtta gactggcaag gtcgattgac tcaaacgatt gctggtaaag
      541 aagtttatcc tcgtccagtt caggacaaat tgcccttgtg gatagctaca ggtggtcatg
      601 tcgaatcaac agtgaagatt gctcaggctg gtctaccgat tgtatatgct attattggtg
      661 gtaatccacg ttattttaaa aagttgattc aggcttatcg tgagattgga agcgaagcgg
      721 tccatgctga caaagacttg aaagtgggag cccattcttg ggggtggatt gcggaagatg
      781 gtgagcaggc ggtgaaagat tatttccatc cgactaagca agtggtggat gctatttcca
      841 aagaccgtcc gcactggcag gaattgcgtt atgagcaata tttggagcag gtagggtcaa
      901 atggcgccat gtttgttggc aatccagatc aggtggccga aaaattgatt cgcatgatag
      961 aggatttagg attggaccgc ttcatgcttc atctaccgct tggttctatg cctcatgacc
     1021 aggttctgag agctattgaa ctcttcggaa cacaagttgc acccaaagta cgagcttatt
     1081 ttgctatgaa agaggcttaa taaaaaatcc taatcaagtt tattaggaca acaaatattg
     1141 tacgaaaatt aatcccccga gctataatgc ttgggggatt tttctatagg agggctagtt
     1201 tagttctctt ttttattttt tagtaagaaa ccgagaccaa ggagcgcaag gaggctgatt
     1261 cctgcaaata ggagtttgtt ttcgttttta attcctgtat ttggaagttc agcttgtcta
     1321 tctggggttg caggtatatt tttcttgcta gagttttcta ccgattcgtt tcgaaccgct
     1381 tcttttacag atgatgcttg tgcttcttgt gctggttgtt cagcttgtga atcagctgta
     1441 gcttggctag gtttattttc cgcatcagct actttggtat ctggtttagt agaatcaggt
     1501 ctagcttctg gagctggatc ttgatgttca gggtgagaag cttcattttg atgttcaggc
     1561 ttggaagggg ttgagtctgg tttctcttct gcagttgact catggctagt tccattttga
     1621 gagactcgaa gaacagtagc tgtaagggca ttcaatttca agcctttttc agtccattca
     1681 agtcctttcg ggttggcaat tccgactgat cctgcttggt tttcatctgc caaaacttcc
     1741 gcatttctta gatgtgcaaa ggcagttccc aaattaaatt cgcgagcttt ttcatccgca
     1801 ttgacaaaga ctgcgtagat atcgccgttt ggagcagtga tttgatagcc aatcactaca
     1861 tcctcttttt ccacaccatt ttggcctggg acagtgatga ggtggacacg gtctttgata
     1921 tcttgaagac tcttaagtcg gaaggcatct gtagattgac gaagggcaat caaacctttc
     1981 atatagtcac ggctcttgac attttcagga taagctttac catctgtagc cttagtccag
     2041 tcaaacttgt tgactgcatc actagaatcg taagagtcat ggatgaagta aggatagtca
     2101 aatgggttgc cgtccttatc acgcaacaag tgagatttgt ttggaacctt atcctctgct
     2161 actggagtct tgtaggctgg gtcacggaat tgtttagtac gtccatattc ctgaccggag
     2221 tggataaatg gagttccttg agctgtcaag accatgagat ttccaagtcg taaacgacgg
     2281 tggatttcag catagttctc agccttgctt gggtcttttt tgatagactg ggcaatgatg
     2341 tcaaagaggg tcaagttatc atgggctgcg atgtattgga tgacatctcc agggctgtca
     2401 gcttcaaagt tagttggttg agcaatgaga tttttaaaga tggtgttgac atcacgcttg
     2461 ccacctgtga taaaggcagg ttgaccttcg tttggataac cagatttgag gttgttacgg
     2521 atgtcatctg aaaagacagc gacagtatcg gtatgtttca tccaatcttg gtcagcagct
     2581 ttagtaggca tgttttcatc accggcatag gttctccaac cttcaccaag catgatgagg
     2641 tttggattga gggcgcgtgc agccttgtaa gcttcttcga tagaagcggc gtcatggtct
     2701 cccatcatat cgaaacggaa gccatccact ttgtaggtat caactaggta tttgatagag
     2761 tcaattagga gccgtttggt catatggtgg gttgtcccca agcgtccacc accaaagcta
     2821 gttcgaggtg tgccatcggc atccataaag tggtagtagt ttggttccaa atcttcaaag
     2881 agatcgactt tggctgtgtg gttataaacg acatctagga tagctcccat accacgtttg
     2941 tggatttcgt tgatgaggtt tttaaattct gcgattcgtt tttctggatt cttaggatcg
     3001 cttgagtaca taccagtcaa ggagaagtag ttttgagggt catatcccca gttgtagttg
     3061 ctgttgcttg aagcgtagtc agacaagcgt tcatggtttt tcaattcatt gacaaagtag
     3121 taagacaaga ctggaaggag ctggatatgg gttacaccca agtctttgag atagtctagt
     3181 ttttcaatga aggcttcaaa agtcccaaat ggtttggtca agtcttttgc aatggcagga
     3241 tctgaagtga aatcacgcac atgagcttcg tagataacgg cgtcttcacg agtcttgaaa
     3301 ttgtgaatct taccataagt caagtcttga ggtccgagtt tagctggatc tacaaaggcg
     3361 gctttagcca ctttatgggc atcgtcaatc ttggaatcgt cgctattcca agcagcaaga
     3421 gatttagcgt aaggatcgag tgcaagaaca gttttacctt gacgctcgat ttggtattga
     3481 taatagtagc cagtgaaatc tgtgattccg agtttgtttg tgctgtctag agtttgtttc
     3541 caagttcctc tttccccttt ttcaagagcg acagttccaa ctactttgtc agggtcattc
     3601 ttgtcgtaga caacaacaga aaccttatca gcacttggtg accaaagggt caaatcaact
     3661 tgttttcctt cttcttttag gtcagctccc agtttgccat catagctgta tgtctcatct
     3721 ttcaggcgcc agcttgtttt ggtagtgaat tggtcggaat tgtagctaac agtataagga
     3781 tgttttgtgt cagagaaatc tccgctgtag gtcactttct taccagcttc atcgattgca
     3841 acatcggtaa tagttacctt gtttcctagg tgattagtga tgttggagtg tttgaggata
     3901 tcttcttttt tagcaccgac aagtgttgaa aagctacttt caatgctaga agtgcctacg
     3961 tgttgggctc ctgtcatacg gatatcatgg acatagtatg gatttgtgta aatcgattca
     4021 tcatcgtctt ttaggaaaat ttggctatga tttttcaaat ctgtgaactt ataattttct
     4081 ttacggattt tcacgtcgtc tccttgtttg ctctcatcta gtaataaaaa tccaaattct
     4141 cttgcggctt cattaagagg aatgtcgata tagcggccat atttgcctgt agccgtaaag
     4201 tctgttccgt caggccattg agcgctactt ggatttttca catctcccca gtaccagaga
     4261 gatttcttgt catagttgcc atctgtgcgg tagtagttga cgcgaacagt tcctgcaggc
     4321 tgtggctcgt aagagaaaac cttgtaatct tggtctaacc aagcttcgtt catttttgga
     4381 actagttttt ctacagattt atcgccggtt agattttttc cagctgtatt gttgatgagg
     4441 aagctaattt tcttggcttg ttctcccttt aatttgacat ctaggtaata gccgtagtca
     4501 tctttcttgg catccttgaa ggacaaagct ccgtttggcc agttttcaga tggtttttca
     4561 acatcgtccc aagtccatag tccttgagca tccttgtttt cttcaggaag ttttttgaca
     4621 tggatacgga agtagttatc ttcgatgggc tcttctgcct tagtttcagt tgttactgga
     4681 ctagtagaag tagttggctc acttgaacga tcttgtccag tttgtggtgc tggatcggct
     4741 gggcttgcag caggtttttc ttctgttttc tctagggaag cgtttgcatt tccaggtgaa
     4801 gaaatatcac tttcgttctt accagagcca gctgctgtat cagtaagagg ttgggcaagg
     4861 gtggttgtat ttctgttgtt gggttcgtta gtggttggtg tactttcgtc ggatgagata
     4921 gttggtgtag ccatggcaag caagacaagg cttgcgccga taaggacaga accagttcca
     4981 tttttgaggg aacggatgct gtagaccatt tttttctcag tgtgagatgg tgtttttctc
     5041 ataatgattc tccaatcaat aaatttctat atcagtatag catgtagtaa aacaatatgc
     5101 aagcgttttc tttgatttgt gaaagaaatt cttacttttg agaagttttc cgtactattt
     5161 tatatatcag tataaatgac ggagataaaa atgtcacgta agccaagccg tgttattagg
     5221 aagatgatgt gttctcagct atttttattc agaaattgat ctctaacatt accaataaaa
     5281 aagaaaaata tcttgacaag caagggaaaa ttttgttaca ataatagacg gtacttttta
     5341 cttttggtct ctcaagagtg tacagggacg tgctgacaaa tgttgcaaaa gtacacacag
     5401 atgatatctg tcaccaagtg tatcatcacc aaaaataaaa aaacacagga gaatgtagat
     5461 gcctacaatt aaccaattgg ttcgcaaacc gcgtaaatca aaagtagaaa aatctaaatc
     5521 accagctttg aacgttggtt acaatagtca taaaaaagtt caaacaaacg tttcttcacc
     5581 acaaaaacgt ggtgttgcaa ctcgtgttgg aacaatgaca cctaaaaaac ctaactcagc
     5641 ccttcgtaaa ttcgctcgtg tacgtttgag caaccttatc gaagttactg cctacatccc
     5701 aggtatcgga cacaacttgc aagagcacag cgtggtgctt cttcgcggtg gacgtgtaaa
     5761 agaccttcca ggggtacgtt accatatcgt ccgtggtgca cttgatactg caggtgttaa
     5821 cgatcgtaaa caaggccgtt ctaaatacgg tactaaacgt ccaaaagcat aaggaaaggg
     5881 gataaagaga aatgagtcgt aaaaatagag ctccaaaacg tgacgtattg ccagatccgc
     5941 tatacaattc acaactagtt actcgtctta tcaaccgcgt tatgcttgat ggtaaacgtg
     6001 gtactgctgc ttcaatcgtt tacggtgctt ttgagcaaat caaagaagct actggcaacg
     6061 atgcacttga agtatttgaa acagctatgg aaaacatcat gcctgtactt gaagtacgtg
     6121 cacgtcgtgt tggtggttct aactaccaag tcccagttga agttcgtcca gaacgtcgta
     6181 caacacttgg acttcgttgg ttggtaacaa tcgctcgtct tcgtggtgaa cacacaatgc
     6241 aagaccgtct tgcaaaagaa atcttggatg ctgctaacaa cactggtgca gcagttaaga
     6301 aacgtgaaga tactcaccgt atggctgaag ctaaccgtgc attcgcacac ttccgttggt
     6361 aagataggat gcgaaagcgt taagaaagtc ccagagaaaa tagggaatcg aagcaggttg
     6421 cggttgcaac caatgagatt catctttttc tccagacttt tagcttgagc tcaactaaat
     6481 catgatgcta ggaacggtaa ggatgcaagg taaaaatagg aaactgacgc agtattcgac
     6541 gaatacaagg agttttatct ttttcacgca gcatcccgtt ccagctcaca tcggctaact
     6601 aactttagcc cgggttcaaa ttagctaaat cgattagtat tagctataac tcagcttacc
     6661 atctcgtaag ttgaaaccaa caatagcatg aaaacattga gaacgggtag gtcctgccta
     6721 tccgttttta ttaaaatcgt gttataatag aatagaaatc aaaaataaat aggagaaaca
     6781 aacctcatgg cacgcgaatt ttcacttgaa aaaactcgta atatcggtat catggctcac
     6841 gtcgatgccg gtaaaacaac aactactgag cgtattcttt actacactgg taaaatccac
     6901 aaaatcggtg aaactcacga aggtgcgtca caaatggact ggatggagca agagcaagaa
     6961 cgtggtatca cgatcacatc tgctgcgacg acagctcaat ggaacaacca ccgcgtaaac
     7021 atcatcgaca caccaggaca cgtggacttc acaatcgaag tacaacgttc tcttcgtgta
     7081 ttggatggtg cggttaccgt tcttgactca caatcaggtg ttgagcctca aactgaaaca
     7141 gtttggcgtc aagcaactga gtacggagtt ccacgtatcg tatttgccaa caaaatggac
     7201 aaaatcggtg ctgacttcct ttactctgta agcacacttc acgatcgtct tcaagcaaat
     7261 gcacacccaa tccaattgcc aatcggttct gaagatgact tccgtggtat cattgacttg
     7321 atcaagatga aagctgaaat ctatactaac gaccttggta cggatatcct tgaagaagac
     7381 atcccagctg aataccttga ccaagctcaa gaataccgtg aaaaattgat tgaagcagtt
     7441 gctgaaactg acgaagaatt gatgatgaaa tacctcgaag gtgaagaaat cactaacgaa
     7501 gaattgaaag ctggtatccg taaagcgact atcaacgttg aattcttccc agtattgtgt
     7561 ggttcagcct tcaaaaacaa aggtgttcaa ttgatgcttg atgcggttat cgactacctt
     7621 ccaagcccac ttgacatccc agcaatcaaa ggtattaacc cagatacaga cgctgaagaa
     7681 attcgtccag catctgacga agagccattt gcagctcttg ccttcaagat catgactgac
     7741 ccattcgtag gtcgtttgac attcttccgt gtttactcag gtgttcttca atcaggttca
     7801 tacgtattga atacttctaa aggtaaacgt gaacgtatcg gacgtatcct tcaaatgcac
     7861 gctaacagcc gtcaagaaat cgacactgtt tactcaggtg atatcgctgc tgccgttggt
     7921 ttgaaagata ctacaactgg tgactcattg acagatgaaa aagctaaaat catccttgag
     7981 tcaatcaacg ttccagaacc agttatccaa ttgatggttg agccaaaatc taaagctgac
     8041 caagacaaga tgggtatcgc ccttcaaaaa ttggctgaag aagatccaac attccgcgtt
     8101 gaaacaaacg ttgaaactgg tgaaacagtt atctcaggta tgggtgaact tcaccttgac
     8161 gtccttgttg atcgtatgcg tcgtgagttc aaagttgaag cgaacgtagg tgctcctcaa
     8221 gtatcttacc gtgaaacatt ccgcgcttct actcaagcac gtggattctt caaacgtcag
     8281 tctggtggta aaggtcaatt cggtgatgta tggattgaat ttactccaaa cgaagaaggt
     8341 aaaggattcg aattcgaaaa cgcaatcgtc ggtggtgtgg ttcctcgtga atttatccca
     8401 gcggttgaaa aaggtttggt agaatctatg gctaacggtg ttcttgcagg ttacccaatg
     8461 gttgacgtta aagctaagct ttatgatggt tcatatcacg atgtcgactc atctgaaact
     8521 gccttcaaga ttgcggcttc actttccctt aaagaagctg ctaaatcagc acaaccagct
     8581 atccttgaac caatgatgct tgtaacaatc actgttccag aagaaaacct tggtgatgtt
     8641 atgggtcacg taactgctcg tcgtggacgt gtagatggta tggaagcaca cggtaacagc
     8701 caaatcgttc gtgcttacgt tccacttgct gaaatgttcg gttacgcaac agttcttcgt
     8761 tctgcatctc aaggacgtgg tacattcatg atggtatttg accactacga agatgtacct
     8821 aagtcagtac aagaagaaat tattaagaaa aataaaggtg aagactaatc cgtcctcact
     8881 ctagaaggaa gtcacttagt ggcttccttt tgtctttaga aaatacctct aaatatggta
     8941 aaatagtaga agaataatgt gaggaaaatg aatgtcaaat agttttgaaa ttttgatgaa
     9001 tcaattgggg atgcctgctg aaatgagaca ggctcctgct ttagcacagg ccaatattga
     9061 gcgagttgtg gttcataaaa ttagtaaggt atgggagttt catttcgtat tttctaatat
     9121 tttaccgatt gaaatctttt tagaattaaa gaaaggtttg agcgaagaat tttctaagac
     9181 aggcaataaa gctgtttttg aaattaaggc tcggtctcaa gaattttcaa atcagctctt
     9241 gcagtcctac tatagggagg ctttctctga aggtccatgt gctagtcaag gttttaagtc
     9301 cctttatcaa aatttgcaag ttcgtgctga gggtaatcag ctatttattg aaggatctga
     9361 agcgattgat aaggaacatt ttaagaagaa tcatcttcct aatttagcca aacaacttga
     9421 aaagtttggt tttccaactt ttaactgtca agtcgagaag aatgatgtcc tgacccaaga
     9481 gcaggaagag gcctttcatg ctgaaaatga gcagattgtt caagctgcca atgaggaagc
     9541 gctccgtgct atggaacaac tggagcagat ggcacctcct ccagcggaag agaaaccagc
     9601 ctttgatttt caagcgaaaa aagctgcagc taaacccaag ctggataagg cggagattac
     9661 tcctatgatc gaagtgacga cagaggaaaa tcgtctggta tttgaagggg ttgtttttga
     9721 tgtggagcaa aaagtgacta gaacaggtcg tgttttaatc aactttaaaa tgacggacta
     9781 tacttcaagt ttttctatgc aaaagtgggt taaaaacgag gaagaggccc agaagtttga
     9841 cctcatcaag aagaattctt ggctccgagt tcgagggaat gtggagatga ataacttcac
     9901 acgcgatttg actatgaacg tacaggatct gcaggaagtt gttcactatg agcggaagga
     9961 tttgatgcca gaaggtgagc gtcgggttga gtttcatgct catactaaca tgtcgactat
    10021 ggatgctttg ccagaggtcg aagagattgt tgcaacagct gctaagtggg gacacaaggc
    10081 ggttgctatc acggaccatg ggaatgtcca gtcctttcca catggctata aggcggctaa
    10141 gaaagcggga atccagctga tctatgggat ggaagccaat atcgtggagg accgtgtccc
    10201 tatcgtctat aacgaagtgg agatggactt gtcagaagca acctacgtgg tctttgacgt
    10261 ggaaacgacg ggactttcag ctatctataa tgacttgatt caggttgcgg cttctaagat
    10321 gtacaagggg aatgttattg ctgaatttga tgaatttatc aatcctgggc atcccttgtc
    10381 agcctttact acagagttaa ctggaattac agatgatcat gtcaaaaatg ccaaaccact
    10441 agaacaagtt ttgcaagaat tccaagaatt ttgcaaggat acggtcctag ttgcccacaa
    10501 tgctaccttt gacgttggct ttatgaatgc taattatgag cggcatgatc ttccaaagat
    10561 tagtcagcca gttattgata cgctggagtt tgctagaaac ctctatcctg agtataaacg
    10621 ccatggtttg gggcctttga ccaagcgttt tggtgtggcc ttggaacatc accacatggc
    10681 caactacgat gcggaagcga ctggtcgtct gcttttcatc tttatcaaag aggtagcaga
    10741 aaaacatggt gtgaccgatt tagctagact caacattgat ctaatcagtc cagattctta
    10801 caaaaaagct cggatcaagc atgcgaccat ctatgtcaag aatcaggtag gtctaaaaaa
    10861 tatctttaag ctggtttcct tgtctaatac caagtatttt gaaggagtgc cacggattcc
    10921 gagaacggtt ctagatgccc atcgagaggg cttgatttta ggttcagcct gttcagaggg
    10981 tgaagttttt gacgtggtcg tttctcaagg tgtggatgcg gcggttgagg tggccaagta
    11041 ttatgatttt atcgaggtca tgccaccggc tatctatgca cccttgattg ccaaagagca
    11101 ggtcaaggat atggaggaac tccagaccat tatcaagagt ttgatagagg ttggagaccg
    11161 ccttggcaag cctgttctgg ctacgggaaa tgttcactat atcgaaccgg aagaagagat
    11221 ttatcgtgaa attatcgtcc gtagtttggg acagggtgcg atgattaatc gaactatcgg
    11281 tcatggtgaa catgcccaac cagcaccact tccaaaggct cattttcgaa cgactaatga
    11341 gatgttggat gaatttgcct ttttgggaga ggaactggct cgtaaactgg ttattgaaaa
    11401 caccaatgcc ttggcagaaa tatttgaatc cgttgaagtc gttaagggtg acttgtatac
    11461 gcctttcatc gacaaggctg aagaaacagt tgctgagttg acctataaga aagcttttga
    11521 gatttatgga aatccgctgc cagatattgt tgatttgcgg attgaaaaag aattaacatc
    11581 catactgggg aatggatttg ctgtgattta tctggcatcg cagatgctgg tgcaacgttc
    11641 taatgaacgg ggttatttgg ttggttctcg tgggtctgtc ggatctagtt tcgttgcgac
    11701 catgattggg attacggagg tcaatcctct ctctcctcac tatgtctgtg gtcagtgtca
    11761 gtacagtgag tttatcacag atggttcgta cggttcagga tttgatatgc cccataagga
    11821 ctgtccaaac tgtggtcaca aactcagtaa aaacggacag gatattccgt ttgagacctt
    11881 ccttggtttt gatggggata aggttcctga tattgacttg aacttctcgg gagaagatca
    11941 gcctagcgcc cacttggatg tgcgtgatat ctttggtgaa gaatatgcct tccgtgcggg
    12001 aacggttggt acggtagctg ccaagactgc ctatggattt gtcaagggtt acgagcgaga
    12061 ttatggcaag ttttatcgtg atgcagaagt agaacgcctc gctcaaggag cggcgggtgt
    12121 caagcggaca acaggccaac acccgggggg aatcgttgtt attccgaact acatggatgt
    12181 ctacgatttt acgcctgtcc agtatccagc agatgatgtc acggctgaat ggcagaccac
    12241 tcactttaac ttccacgata tcgatgagaa cgtcctcaaa ctcgatgtac tgggacatga
    12301 tgatccgacc atgattcgaa aacttcagga tttgtctggt attgacccta ataaaattcc
    12361 tatggatgac gaaggcgtga tggcactctt ttctgggact gatgtactag gggtaacacc
    12421 tgaacaaatt ggaacgccta cgggtatgtt ggggattcca gagtttggaa caaatttcgt
    12481 acgtggaatg gtagacgaaa cccatccgac aacctttgcg gaattgcttc agctgtctgg
    12541 tctgtcccac ggtactgacg tttggttggg gaatgctcag gatctgatta agcaaggaat
    12601 agcggaccta tcgactgtta tcggttgtcg ggacgacatc atggtttacc tcatgcatgc
    12661 gggtctggaa cctaagatgg cctttaccat tatggaacgg gtacgtaagg gtttgtggct
    12721 aaagatttca gaagaggaga gaaatggcta tatcgaagcc atgaaggcta ataaggtgcc
    12781 agagtggtat atcgaatcct gtgggaaaat taagtacatg ttccctaagg cccatgcggc
    12841 agcctacgtt atgatggcct tgcgtgtagc ttacttcaag gttcaccatc ctatttatta
    12901 ctactgtgct tacttctcca ttcgtgctaa ggcttttgat atcaagacca tgggtgcggg
    12961 cttggaggtc atcaagcgca gaatggaaga aatctctgaa aaacggaaga acaatgaagc
    13021 ctctaatgtg gaaatcgatc tctatacaac tcttgagatt gtcaatgaga tgtgggaacg
    13081 aggtttcaag tttggtaaat tagatctcta ccgtagtcag gcgacagagt tcctcatcga
    13141 cggggatacc cttatcccac catttgtagc aatggatggt ctgggagaga acgttgccaa
    13201 gcaactggtg cgggcgcgtg aagagggaga attcctctct aaaacagaac tacgcaagcg
    13261 tggtggactc tcatcaacct tggttgaaaa gatggatgag atgggtattc ttggaaatat
    13321 gccagaggat aaccagttga gtttgtttga tgagttgttt taaaaaattg cttaataatc
    13381 tattaaaaga ggctaacgta tatccaatag atttacatta gctttctttt ttgttaaaat
    13441 agtctatgga aagagggtga gagtatgtca aagatgagta taagcatccg tctggatagt
    13501 gaggttaagg agcaggccca acaggtgttt agtaatctgg gaatggatat gacaacagct
    13561 attaatattt tccttcgtca ggcaattcaa tatcagggat taccttttga tgttagacta
    13621 gacgaaaatc ggaagttgct ccaagcgtta acggatttag accaaaatcg taatatgagc
    13681 cagtcttttg aatcagtctc agatttgatg gaggacttac gtgcttaaga ttcgttatca
    13741 taaacagttt aaaaaagatt ttaagttggc tatgaagcgt ggtttgaagg cagaattatt
    13801 agaagaagtt ttgaattttc tggttcaaga aaaagaacat cctgccagat atcgtgatca
    13861 ttcattgacg gcatccaagc attttcaagg agttcgtgaa tgccataccc agccagattg
    13921 gcttttggtt tataaagtag acaagtcgga attgatttta aatttgctga ggacaggcag
    13981 tcacagtgat ttattttaat ctattttaag ggggttctca tgaaactaag aatatttgcg
    14041 gaagataagc cggctaagaa ggtatttgaa tatcaattag aacttgctga tcgtacaatt
    14101 cttctatcga cagcactctt gtcaggtgct attgctttag caggaatctt ttctgctttg
    14161 aaagaaaaat aaaaatagaa aagagaaaac agaatggttt taccaaattt taaagaaaat
    14221 ctaggaaaat atgcgaaatt gttggttgcg aacggaatta acgtgcaacc tggtcacact
    14281 ttggctctct ctattgatgt ggagcaacgt gaattggcac atctaatcgt gaaagaagct
    14341 tatgccttgg gtgcgcatga ggtcatcgtt cagtggacag atgatgtgat taaccgtgag
    14401 aaattcctcc atgccccgat ggagcgtttg gacaatgtgc cagaatacaa gattgctgag
    14461 atgaactatc ttttggagaa caaggctagc cgtcttgggg ttcgttcatc tgatccaggt
    14521 gccttgaacg gagtggacgc tgacaagctt tcagcttctg ctaaagctat gggacttgcc
    14581 atgaagccta tgcgtatcgc aactcaatct aacaaggtta gctggactgt agcagccgct
    14641 gctggacttg agtgggctaa gaaagtcttc ccaaatgctg cgagcgacga agaagcagtt
    14701 gatttccttt gggatcaaat cttcaaaact tgtcgtgtct acgaagcaga tcctgttaag
    14761 gcttgggagg aacatgcagc cattctcaag agcaaggccg atatgcttaa taaggagcaa
    14821 ttttcagccc ttcactacac agcgccagga acagatttaa cacttggttt gccaaagaac
    14881 cacgtttggg aatcagctgg tgctgtcaat gcacagggcg aagaattctt gccaaatatg
    14941 ccgacagaag aggtcttcac agcgcctgac ttccgtcgtg cagatggtta tgtcacttct
    15001 acaaaaccgc ttagctacaa cggaaatatc attgaaggca ttaaggtgac ctttaaggat
    15061 ggacaaatcg tagatatcac tgctgagaag ggtgatcagg ttatgaaaga ccttgtcttt
    15121 aaaaatgcgg gtgcgcgtgc cttgggtgaa tgtgccttgg taccagatcc aagtccaatt
    15181 tctcagtcag gcattacctt ttttaacacc cttttcgatg aaaatgcgtc aaaccacttg
    15241 gctatcggtg cagcctatgc gactagcgtt gttgatggag cggagatgag cgaagaggag
    15301 cttgaagctg cagggcttaa ccgttcagat gttcacgtag actttatgat tggttctaac
    15361 caaatggata tcgatggtat tcgtgaggat ggaacgcggg tacctctttt ccgtaatggg
    15421 aattgggcaa attaaggaga taatatgtta ggaagtatgt tcgttggtct cctagtggga
    15481 tttttagcag gtgctatgac caatcgtgga gagcgaatgg gatgttttgg aaaaatgttt
    15541 ctcggttgga tcggagcctt tctaggtcac ttgctctttg gaacttgggg gccagtttta
    15601 tcaggaacag ctattatccc agcgatttta ggagccatga ttgttttagc tattttttgg
    15661 agacgaggaa gttaatttcc taaatctgat actcaatgaa aatcaaagag caaactagga
    15721 aactagccgc aggttgctca aagcactgct ttgaggttgc agatagaact gacgaagtca
    15781 gtaacatata tacggcaagg cgacgttgac gcggtttgaa gagatttttg aagagtatga
    15841 aacgaaaagg aggttggtca ttgtactagc ctccttttga tatgatataa tagttctatg
    15901 agattagata aatttttagt tgcctgtgcg gtgggaagtc ggactgaggt caaaaacttg
    15961 ctcaaggctg ggcgcgtgac tgtaaatggt aaaaaagaaa aatcagctaa attgcagatt
    16021 gatgaaaaaa tagatgagat tcgctttgat gggcaagtgt tggagtatga agagtttgtc
    16081 tactacatga tgaacaagcc caaaggagtt atctcagcga ctgaggatcc caagcacaga
    16141 accgttctgg acttgttgga tgacttggcg cggagtaagg aagtttttcc agtaggacgc
    16201 ttggatattg acacgcatgg tcttttgctc ttgaccaata atggtcagct ggctcatgtt
    16261 cttctttcgc ccaagcgtca tgtggacaag acttatcagg ctcaggtcaa gggaattatg
    16321 acccaagaag atgtggagac atttatcaag ggcattccgc tcaaagactt tacctgtcag
    16381 cccgctagac tggagattct ttccacagat gcagaaaaga atcagagcca aatccgtgtg
    16441 accattgcag aagggaagtt tcatcagatc aagcgtatgg tgggctactg tggcaaggaa
    16501 gtggtggact tgcaacgatt gactatggga actttagtat tagatgagaa cctggaacga
    16561 ggggaatggc gtcgcttgac caaggaagaa ttagaaattc tccgcgctaa tattatttaa
    16621 tttagtttaa tactcaatga aaatcaaaga gcaaactagg aaactagccg caggctgtac
    16681 ttgagtacgg caaggcgacg ttgacgtggt ttgaagagat tttcgaagag tataaattcg
    16741 aaaaaggtga gggacaatgt cctcgccttt tatgtttttt agttgcttcc tttgtgaaaa
    16801 gagttataat agactgtaga ataaaaggag gaatctatga acgcgattca agaatcattt
    16861 actgataaac tatttgccaa ctatgaagca aatgtaaaat accaagcgat tgaaaatgct
    16921 gccagccaca acggaatttt tgcagctctg gaatgtcgcc aaagccatgt agacaacaca
    16981 cctgttttct cattggattt aaccaaggac aaggtcacta accagaaagc gtctggtcgt
    17041 tgctggatgt ttgcggctct caacaccttc cgccacaaac tcatctcgca atacaaattg
    17101 gagaactttg agttgtcaca agcccacact ttcttctggg ataagtatga gaaatcaaac
    17161 tggttcttgg agcaagtcat tgcgacttca gaccaagaat tgactagccg caaggttagc
    17221 ttcttactcc aaacacctca acaagatggc ggtcaatggg atatggtcgt ttccctcttt
    17281 gaaaaatacg gtgtcgtgcc taagtcagtt tatcctgagt ctgtttcatc tagcagcagt
    17341 cgtgagctaa atgcgatcct taataaattg cttcgtcaag atgctcaaat cttgcgtgat
    17401 ttgcttgttt ctggtgcaga tcaagcgact gttcaagcta agaaagaaga cctcttgcaa
    17461 gaaatcttta actttcttgc tatgtcatta ggacttccac cacgcaagtt tgactttgct
    17521 tatcgcgata aagataacaa ctataaaagt gaaaaaggaa tcacaccaca agagttttac
    17581 aagaaatatg tcaatcttcc tttagaagac tacgtttctg ttatcaatgc tccaactgct
    17641 gataaacctt acggaaaatc ttacacagtt gagatgttgg ggaatgtggt tggtagccgt
    17701 gcagttcgct acatcaacgt tccaatggag cgcttgaaag aattggcgat tgcccaaatg
    17761 caagcaggtg agactgtttg gtttggttct gatgtcggcc agctcagcaa ccgtaaggct
    17821 ggcatccttg cgacagatgt ttatgacttt gaatcaagca tggacattaa acttactcaa
    17881 gacaaggctg gacgtttgga ctatagcgaa agcttgatga cccacgccat ggtcttgaca
    17941 ggtgttgact tggacgaaaa tggtaaatca accaagtgga aggttgaaaa ctcatgggga
    18001 gacaaggtcg gtacagatgg ttactttgtt gcctcagacg cttggatgga cgaatacaca
    18061 taccaaatcg ttgttcgtaa ggaattgctg acagcagaag aacaagctgc ctatggagca
    18121 gaaccaatcg tacttgcacc atgggatcca atgggagcct tggctgaata aaagcataga
    18181 aaaaaggaat cagattttag aacctggttc ctttttagtt gcttgattac atgatgtgaa
    18241 gaacatgtgc cacaataccc actgcgaaga gggcaaggat aatagtgatt ggagatactt
    18301 ttttcttaag taagtacatg caaagtaaag taaggagtag tcctgataat ccaggaatca
    18361 acatatccaa gttttgttgg aaagtagtaa ctttttcagg agtttgagac aatccttgtc
    18421 ctacttgtgc gaatgcttct tggatacctt tagacccttc tggcaattta tcccaatgga
    18481 tataagcctt ttcatctagt tgaactttag aaacatcgaa agcaaattta atatttaccc
    18541 agcgttgaac aaggacagca agaatgaaca tcccaaggat agaagctcct ttagtgatat
    18601 cttgaaggat accaccagac atatctttag tgatttctga tccagccttg tatccaatct
    18661 cttgaacata ccacaagaat gacatacgaa tcaagttcca tgcaacaaag aagaggagtg
    18721 gccccaagat attgccagta agggcaagtg aagcaccgag agatccaagg attgggcgta
    18781 ctgtaaacca gaatactggg tcaccgatac cagcaagagg tcccatcata ccgattttaa
    18841 ccccttggat agcagcgtca tcgatttcca caccgttagc acgttcttct tcaagcgcaa
    18901 gagtaacccc catgactgga gcagctacgt atggatgagt gttgaagaac tcaaggtgac
    18961 gctcaagagc agcgatttga tcttcttttt tagtatagag ttttttgata gctggaatga
    19021 gtgtataagc ccagcccaag ttttgcatcc gttcaaagtt ccaagaccct tgtaagaagg
    19081 ttgaacgcca ccaaactttt ttacgatctg atttagttaa ttgaagtttt tcagtcatga
    19141 tgttttcagt cctttcttat cttagtagtc ttctaggata tcgccgattg ggtcgttaga
    19201 agttgcggct cctccgccac catttccacc agttttagaa aggtgaaggt agataagagc
    19261 gatagcaaca ccgatagcac cgaatccgat tagagtaata tctgacacag cagcaagaac
    19321 gaaaccaaga gcgaagaatg gccatacttc acgagttgcc atcatgttga taaccatggc
    19381 gtaaccaacg gcaacgacca taccaccacc gatagccata ccatctttga gccagtctgg
    19441 catggcacta aggatacttt gtacagtttc agttggtacc ataaggagaa gagctgcagg
    19501 aagcgcgata cgaagtcctt ggaaaagtag cgcaatgaaa tgagcacgct ccacagcgcc
    19561 gaagtcacct tttttagcgg cagcatcagc agtgtgaacc aatccaactg aaattgtacg
    19621 aacaatcata gttaagaata gaccagctac ggcaagaggg atagcaaccg cttgggcaac
    19681 accgatacca gtcttggtaa agtcaccacc aagaaccatg ataatggcag cagcgacaga
    19741 agcaagtgca gcatcaggag cgatagcagc accgatattt gaccaaccaa gggcaatcat
    19801 ttgaagcgat ccaccgagga taatccctgc ttccaagtga cctgttacaa gcccaataag
    19861 ggtacaggct acaagtggtt ggtgaaattg gaactggtcg aggatgcctt caagacctgc
    19921 aaagaaggct acaacgacta ctaaaaccat agaaataata gacatgttta aaatcctttc
    19981 ataaataatg gcttatttga cattggcttt gttaatcaag tcaaacaaat cttttttaga
    20041 atcatttggt actttacgga catcaaattc aacacccaag tcacgcattt tttcaaatgt
    20101 agcaacatct tctttgtcca tagacaaaac ggtattgacc aatgttttac ctgttgagtg
    20161 agccatagaa ccaacgttaa gagtcttgat tggcacgccg ccttcgatgg cacgaagggc
    20221 atcttgaggt gtttcaaaca agataagggc atgtgtttct ccaaaacgtg ggtcttttga
    20281 aatctcaatc agtttttgaa ttggaaccac gttagccttg acattacctg gagctgcttg
    20341 tttaatcaat tctttacgaa ggtcgtcttt agccacgtta tctgaagcaa cgatgatacg
    20401 atttgctttt gaatctggag tccaagcagt tgcaacctga ccgtgaagta gacgtgtgtc
    20461 aagacgggca agattgattt tcaatttacc gtctccgata acagttcctt ctgggatagc
    20521 agtttgggca actggagcag ctgcagcgct tgcaacttct tcaactggat ttagctcttc
    20581 tggaagagct ttgatgccat ctttggcttc tttaatgata ttagcagcga ctttttctac
    20641 acctgcagca gcgtccatga ggcgctctgt gtaggcttga atcaacatcg gtaagttaag
    20701 tcctgtgatg atggcaaact tacgctcagg attttctccc atcacgcgac tagcttggtt
    20761 aaatggagaa ccactccaaa ggtcagccaa aactagaacc tcatcttctg cgtcaaatgc
    20821 agcaacagcg ttattaaact tagcgtatag atcatcagga ccttcatttg gcataaaggt
    20881 cacaacttga accttttctt gttcaccaaa gatcatagat cctgactgat gaatacccgc
    20941 agcaaattcg ccgtggctcg caataatgat tccgatactc attattgtca ttcctccttt
    21001 tttgttttag ttttcattta agaaaacttt aagactgttt aagtataaac cgttttcata
    21061 aaaaaagcaa ctatttatca taaaaaatta aaaaattttt atttttgtat gttgatatgt
    21121 tgagtttttg aggagtaatc ttgaattctt atttaaaatt taatataaaa aagttggaag
    21181 aagcttccaa cttttaaaat aggtttctat taaattagtg ggtgaagtcg agtaccatac
    21241 gtccttggat ttggcctttt tccatttcgt cgaaaatggc aacagcatct tctactggac
    21301 gtttttgaac aactgggact accagacctt ctgcaccaaa ttggaaggct tcttctaagt
    21361 ctttacgagt tccgacaaga gaaccgatga cttggattcc atcgaggact gttttaacga
    21421 tgctgagttc catcatttca gaaggaagac caacagcgac gacgcgacca ccagcacgaa
    21481 tggagtcaac agcctggttg aaggcaactt tagacacagc agttacgaca gctgaatgag
    21541 ctcctccatc agttttttct ttaatgagtc cagctacatc ttcaacttcg aggccgttaa
    21601 tcacaatgtc agcgcctact tcttttgcaa gggtaagttt gtcattgttg atatcgactg
    21661 cgataacatg agcattgaat acttttttag cgtattgaac agcgaggtta ccaagtccac
    21721 cagcaccgta aagaacaacc cattggcctg gttcaacttt tgcttctttg atagctttat
    21781 aggttgttac tccagcacat gtgatagaag aagcttgggc tggatcaagt ccgtcaggaa
    21841 ctttgacagc atagtcagca gttacgatac attgttcagc cataccaccg tctactgagt
    21901 agccagcatt tttcactgta cggcaaaggg tttcgcgacc agttgtacag tattcgcaag
    21961 tgccacatcc ttcaaagaac caagcaacgc tgacgcggtc accgacttta aggcttttca
    22021 catctggagc aatctcttta acgataccga taccttcgtg cccaagaaca cgtcctggga
    22081 cttgaccaaa gtcaccatga gcaacgtgga ggtcggtgtg gcaaacgcca cagtattcaa
    22141 cttctacaag tgcttcccca gtttcaagtg gacggagtac tttttcttca atagcaacac
    22201 cagtgctttc tggatttaca acaacagctt tcatagctat cctccttgat attgaccgag
    22261 aacagggaca acgggactgg attgattttt tgtcaacaga gtcgagtgtg acgagctctc
    22321 ttgtatttat atgtgaagta tatcacaaaa ggaagccttt tccaaggttt tggagacaaa
    22381 aagtagaaca atcgattaac tggttgatga gactgtgaaa agagcacaaa gaccagcttg
    22441 caagctggtc atactcttcg aaaatctctt caaaccacgt cagcttcatc tacaacctca
    22501 aagcagtgct ttgagcaacc tacggctagc ttcctagttt gctctttgat tctcattgag
    22561 tatcagtata ggttataaga ataagtcttg tagggttttg gcaaccccat cttggtcgtt
    22621 ggtaagggaa atttgctcat ctgcataagg gagtagctct ggattggcat ttttcatggc
    22681 ataacccttc ccagcaaaag cgagcatttc ggtatcattg tgttcatctc caaaggcaat
    22741 caaatctttt ttgtcacgat tcattatctt gagcaagtag tccaaagcaa aggccttgtt
    22801 gacacctttt ggggtacatt caaggatatt gagcggacct ccccaggtat tgatagaaag
    22861 ttgatgctgg tagaaggcgt tcatttcttt tgccaaggca tatttgtcac tggctctggt
    22921 ctgcaagagg atacagttag ggtccttggt caccaattca ggctggaatt gatcttcagg
    22981 ctggaaagct tctacaccaa atagtttggg attggcaatt tcttcattgg gatttgtaat
    23041 gtagaatttt ttacgatatt ctccagcgat aaaatcggct tgaatgtcct ctgaacgttg
    23101 aaccatatct agcagatatt ttttgtctac agtcaaacac ttttcaaaat cccaaacttg
    23161 gtctggtaaa tgagtaaggg atccgttgaa gttaatcata ggagtgtcta agcccagttc
    23221 acggtaaaaa tcttttgaca tacggtaagg gcgacctgtc gtaataataa cctgatggcc
    23281 tttttcagca acttttttga tggttctttt ggtaaagtca gaaatttgac tgtctgagtt
    23341 gagcagggtt ccatccaggt caactgcaat aatttttttc gtcatatgga cctttctagt
    23401 gtgttttcag ataagatgtc ttctattata acagaaagca ggcagaaaag cagattccaa
    23461 acaaaaaatg aaattggatt aatttcttaa acaaatcaaa caaagacatt gaaaaagtga
    23521 atgataaatg atataattct attattgttc gtaaaaatta aaaggagatt gatgatggac
    23581 aaattattta aactaaaaga gaacggtaca gacgttcgta cagaggttct cgctggttta
    23641 acaactttct ttgcaatgag ctatattctc tttgtaaacc cacaaatact ttcacaaaca
    23701 ggaatgcctg ctcagggcgt cttcctagcg acgattattg gtgcagtagc gggtaccttg
    23761 atgatggctt tttatgctaa cttaccttat gcccaagcac caggtatggg actcaatgcc
    23821 ttctttacct ttacagttgt attcgggctt ggttattctt ggcaagaagc cctagctatg
    23881 gtcttcatct gtgggattat ttcattgatt attaccttga caaatgttcg taaaatgatc
    23941 attgaatcga ttcccaatgc tcttcgctca gctatttcag ctggtatcgg tgtcttcctt
    24001 gcctatgtag ggattaagaa tgctggactt ttgaaattca cgattgatcc aggcaactat
    24061 actgttgtag gagaaggggc tgacaaagct caagcaacga ttgcagcaaa ctcttcagca
    24121 gttccaggat tggtcagctt taataatcca gctgttttag tggctcttgc aggacttgcc
    24181 attactatct tctttgtcat caaagggatt aaagggggaa ttattctctc tatcttgaca
    24241 acaactgttc ttgctattgc agttggtttg gttgatttgt ctagtatcga ttttgctaat
    24301 aaccatgttg gtgcagcttt tgaagatttg aagacaatct ttggtgcagc tcttggttca
    24361 gaaggtttgg gagctttggt ttcagataca gctcgcttgc ctgaaactct gatggccatt
    24421 cttgccttct cattgacaga tatttttgac acaattggta ccttgatcgg tacaggtgaa
    24481 aaagttggta ttgtagcgac aaatggtgaa aatcaccaat cagccaaatt ggataaggct
    24541 ctttactctg atttgattgg aacgacagtc ggtgccattg caggtacttc aaacgtaacg
    24601 acttatgttg agtctgctgc tggtatcggt gcaggtggac gtactggttt gacagccttg
    24661 gttgtagcta tctgttttgc gatttcaagc ttctttagcc cacttctagc gatcgtacca
    24721 acagcggcta cagctccaat cttgattatc gttgggatta tgatgcttgg tagcttgaaa
    24781 aatatccatt gggatgatat gtctgaagca gttcctgcct tcttcacatc tatctttatg
    24841 ggattcagct actctatcac tcaagggatt gcagttggtt tcttgactta cactttgact
    24901 aagcttgtca aaggtcaagt taaagatgtt catgccatga tttggatttt ggatgccttg
    24961 tttatcctta actacatcag catggcctta taatagaatg acccaggggg atttcccccc
    25021 ttttttaata caaaggagat aggtgatgaa agagaaaaat atgtggaaag aattgttgaa
    25081 tcgtgcaggc tggattttgg tctttttact tgccgtcctt ttatatcagg ttcccctagt
    25141 ggttacctct attttgactt taaaagaagt agccctgcta cagtcagggc tgatagttac
    25201 tggcctttca attgtggttc tggctctatt tattatggga gctcgtaaaa ccaagttagc
    25261 tagttttaat ttttcttttt ttagagctaa agatttggca cgtttgggct tgagttattt
    25321 agttattgtc gggtcaaata tacttggttc tatcttgttg caactgtcaa atgagacgac
    25381 aacagctaac cagtctcaga ttaacgatat ggttcagaat agttctctga tttctagctt
    25441 cttcttgcta gccttgcttg ctccaatttg tgaggaaatc ttgtgccgtg ggattgttcc
    25501 taaaaagatt ttccgaggca aggagaactt gggatttgta gtcggtacga ttgtgtttgc
    25561 tttattgcat caaccaagta atttaccttc tttattgatt tatggaggta tgtcgacagt
    25621 tctatcttgg acggcctaca agacccaacg tttggaaatg tcgatcttgc ttcacatgat
    25681 tgttaatggg attgctttct gtttgttggc tcttgtggtg attatgagtc ggacattagg
    25741 aatttctgtg taaaagtttt tatgtaggaa ccgacctctt tctactaggg aaagatgaat
    25801 gcaatcgtgt ccatcttttt ctttttatgg taaaatagaa aaataatatg atgaaaatcc
    25861 ttgagggagt gaccgatatg tcaagtaaag ccaatcatgc aaagacagtt atttgcggaa
    25921 ttatcaatgt aaccccagac tccttttcgg acggtggtca attttttgct cttgagcagg
    25981 cactccagca ggctcgtaaa ttgatagcag aaggagccag tatgctcgat atcggcggag
    26041 aatcgactcg gccgggcagt agctatgttg agatagaaga ggaaatccag cgtgttgttc
    26101 cagtgatcaa agcgattcgc aaggaaagtg atgtccttat ttctatcgat acttggaaaa
    26161 gtcaggtggc agaggctgct ttggctgctg gtgccaatct agttaatgat atcactggtc
    26221 tcatgggcga tgaaaaaatg gcccatgtgg ttgctaaagc tggagcgaaa gtagtcatca
    26281 tgtttaatcc agtcatggct cgacctcaac atcctagttc gcttatcttc cctcattttg
    26341 gctttggtca aacctttaca gaaaaagagt tagctgactt tgaaacattg ccaatcgaag
    26401 acttgatggt ggctttcttt gaacgagcac tagcgagagc ggcagaagct ggtattacac
    26461 cagaaaatat cctgttggat ccaggaattg gctttggtct gaccaagaaa gaaaatctcc
    26521 tccttttacg ggacctggat aaactacatc agaagggcta tccaatcttt ctcggagtgt
    26581 cgcgcaagcg atttgtcatc aatatccttg aagaaagtgg gtttgaagtc aatcctgaga
    26641 cagagcttgg tttccgaaat cgggacacgg cttcggctca tgtaactagt atcgctgcga
    26701 gacagggtgt agaagtggtg cgcgtgcatg acgtagctag tcacaggatg gcagttgaaa
    26761 ttgcctctgc cattcgtctg gctgatgaag cggaaaattt agatttaaaa caatataaat
    26821 aagatgaaag aaattgaaaa caatcagtgg attgctaact accggacgga tcaaccgcat
    26881 tttggattgg aacgaatggt ggaactgtta gctttgcgtg gcaatcccca tctcaaactc
    26941 aaggtcctcc atatcggagg gactaacggc aagggctcga ctattgcttt tttgaaaaag
    27001 atgctagaaa agctagggct gagagttggc gtgtttagct cgccctatct cattcattac
    27061 acagaccaga ttagcatcaa tggggaatcg atctcagaag cgaggctaga agctctcatg
    27121 gcagactatc agtctttgct ggagggagaa gcggtcgcca atttacaggg cacaaccgag
    27181 tttgagatta tcacagccct ggcctatgac tactttgcct cagagcaagt agatgtggcc
    27241 atcatggaag ttggcatggg tggacttttg gatagtacca atgtctgtca gcccattttg
    27301 acaggaatta caactattgg cttggatcat gtggccctac ttggtgacac cttggaggcc
    27361 atagcagagc agaaggcagg tattatcaaa caagggatac ccttggtaac agggcgtatt
    27421 gctccagaag ccttgactgt gattgaccgc attgcggaag ggaaagatgc gccgagactt
    27481 gcctacggga cagattatca ggttcgtcat caagaaagtg tggtgacagg ggaagtcttt
    27541 gactatacaa gtgctgtcag acaaggtcgc ttccagacta gcctgcttgg tttgtaccaa
    27601 atagagaatg ctgggatggc catagcttta cttgatactt tttgtcaaga agatggtcga
    27661 gagctagcaa gcaatgactt tcttggtcaa gccttggaag aaacaagttg gccagggcgt
    27721 ttggaaatcg tgtcaagaga tcccttgatg attttggatg gagcccataa tccccatgct
    27781 atcaaggcct tgttggtaac cttgcaagaa cgttttgcgg attatcataa ggaaatcctc
    27841 ttcacttgta tcaaaaccaa agccttggag gatatgttgg acttgctggg agccatgcca
    27901 gataccgagc ttactctaac acattttgcg gatagtcggg cgacggatga aagcgtgctg
    27961 aaagaggcag ctaagtctag aaatctcagc taccaagatt ggcatgattt tctagagcag
    28021 aatttgacag ataaaaaaga agagaaacaa acagttagga ttgtcacagg ttccttgtat
    28081 ttcttgagcc aagtgagggc ctatctgatg gagaggaaga acgagaatgg atacacaaaa
    28141 gattgaagca gctgtaaaaa tgattatcga ggctgtagga gagaacgcta atcgcgaggg
    28201 cttgcaggaa acacctgctc gtgtagcccg tatgtatcaa gagatttttt caggtcttgg
    28261 tcaaacagca gaggaacatt tgtcaaaatc ctttgaaatt attgacgata atatggtggt
    28321 agaaaaggat atctttttcc ataccatgtg tgaacaccac ttcttgccat tttatggtag
    28381 agcgcacatt gcctacattc cagatggtcg tgtggcaggc ttgtctaagc tagcccgtac
    28441 ggttgaagtt tattcgaaaa aaccacaaat tcaagaacgt ttgaatatcg aagtggccga
    28501 tgccttgatg gactatctag gtgctaaagg agcctttgtt gtcattgagg cggaacatat
    28561 gtgtatgagt atgcgtggtg ttagaaaacc aggcactgca accttgacga cagtagctcg
    28621 tggtctattt gaaacagata aggacctccg cgaccaagct tatcgtttaa tggggctata
    28681 aaaagaatcc gcttcaagcg gatttttcta gaaaggaatc attatggatc aactgcagat
    28741 taaggatttg gaaatgtttg cctatcatgg tctttttcct agtgagaaag aattggggca
    28801 gaaatttgtc gtttcagcca tcctatccta tgatatgacc aaggcagcta cagacttgga
    28861 tttaacagcc tctgtccatt acggagaatt atgtcagcag tggacgactt ggtttcagga
    28921 aacgagtgaa gatttgattg aaacggtagc ctataaactg gtggaacgta cctttgagtt
    28981 ttatcctctt gtccaagaaa tgaagttgga actgaaaaaa ccttgggcac cggtgcattt
    29041 gtcactagat acttgctcgg taaccattca tcgccgcaag caacgagcct ttatcgccct
    29101 aggaagcaat atgggagata aacaagcaaa cttgaagcaa gccattgaca aactgcgagc
    29161 tcgtggcatc tatattctca aagagtccag tgtcttagcg acggagcctt ggggtggagt
    29221 ggagcaggat agctttgcca atcaagtggt tgaggtggaa acctggctac cagcacaaga
    29281 cttgttagaa accttgttag ccattgagtc agagctggga cgggtgagag aagtgcattg
    29341 gggacctcgt ttgattgatt tggacttgct ctttgtggag gaccagatcc tttatacaga
    29401 cgacctcata ttgcctcatc cttacatagc ggaacgcctt tttgtccttg agtccttaca
    29461 ggaaattgcg cctcatttta tccatccgac attaaaacaa ccgatccgca acttgtatga
    29521 tgctttgaaa aaatagaaaa actctagttt tcagttactt gcaactgaag gctagagttt
    29581 ttaaaatagg tcattttctt ctgggaggag gatagtttct ctaccgtaca tgtctaaaac
    29641 cagtactctt gggggataac gagggtcgaa aggatggtta aagtcaaaat caatggctgt
    29701 agggaggtgt tgacttgaaa agtggaaggt aatctttcct tggttattaa gcaattgaaa
    29761 ctcgagttct tcttccaatt caaagacatt ttttaagaaa tgatcgatga tataccaaaa
    29821 agagtcaatg atgtcatcgg gcaagctggt aacaatgcca aaactagcag accgcatgtg
    29881 ggtattggta aaagccatat ctctgtcccc tttcttttcc cttatcatac agcaaatagg
    29941 attaaaaatc aagaaaaggt gattttttga aaaggatttt aactacaggg aaaaataagg
    30001 aaaaaaattc ccaaaaatct accgaagtta ataggtaaat tcccaaatta acttgattat
    30061 ataactttca gtt
//
LOCUS       DAVBDR010000022        29757 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.022, whole genome shotgun sequence.
ACCESSION   DAVBDR010000022 DAVBDR010000000
VERSION     DAVBDR010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 29757)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29757)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29757
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.022"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            132..494
                     /locus_tag="VQ540_000994"
     CDS             132..494
                     /locus_tag="VQ540_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2544812.1"
                     /translation="MRLASESRQILDKLKDDVYNKLGYEVSYSSIVSQAVREYVPKKE
                     RIDWIKLKETAIPFSSLKQSNNWEYQTSLMLEKDVLILLSELQNFFLDVFQAKRIHRA
                     FCIRLCLRAQFLLSNNDS"
     gene            902..1201
                     /locus_tag="VQ540_000995"
     CDS             902..1201
                     /locus_tag="VQ540_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001081475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2544813.1"
                     /translation="MNRNVLNFLRTESAERVSLYIDKANRLEGDVTLLAPSSQDLEDI
                     KNAMFSNPNLELKVARLDVMKKIAYASTRNHYLTGATIFGDISKGTYNCDPKSYV"
     gene            complement(1296..1733)
                     /locus_tag="VQ540_000996"
     CDS             complement(1296..1733)
                     /locus_tag="VQ540_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2544814.1"
                     /translation="MKKLYRIHFIAIAVIDLLLFAFFITRLETSFEWLLLSGLIFFLA
                     QGLLLFLLVVRLKHQFAEIYPQINKKIRFYYLGVLTIDFLFFVLLAFISSQRFSSLMP
                     IITACHSTFYYMTADYLRENYPDFYDKHISNTYTILSISSFLV"
     gene            complement(1864..2498)
                     /locus_tag="VQ540_000997"
                     /pseudo
     CDS             complement(1864..2498)
                     /locus_tag="VQ540_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819460.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter"
     gene            complement(2708..3358)
                     /locus_tag="VQ540_000998"
     CDS             complement(2708..3358)
                     /locus_tag="VQ540_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000188500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HET2544815.1"
                     /translation="MTPNKEDYLKCIYEIGIDLHKITNKEIAARMQVSPPAVTEMIKR
                     MKSENLILKDKECGYLLTDLGLKLVSELYRKHRLIEVFLVHHLDYTSDQIHEEAEVLE
                     HTVSDLFVERLDKLLGFPKTCPHGGTIPAKGELLVEINNLPLADIKEAGAYRLTRMHD
                     SFDILHYLDKHSLHIGDQLQVKQFDGFSNTFTILSNDEDLQVNMDIAKQLYVEKIN"
     gene            3470..4312
                     /locus_tag="VQ540_000999"
     CDS             3470..4312
                     /locus_tag="VQ540_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HET2544816.1"
                     /translation="MTKIALLSDIHGNTTALEAVLADARQLGVDEYWLLGDILMPGTG
                     RRRILDLLDQLPITARVLGNWEDSLWHGVRKELDSTRPSQRYLLRQCQYVLEEISLEE
                     IEVLHNQPLQIHRQFGDLTVGISHHLPDKNWGRELIHTGKQEEFDRLVTHPPCDIAVY
                     GHIHQQLLRYGTGGQLIVNPGSIGQPFFLDAQLRKDLRAQYMILEFDDKGLVDMDFRR
                     VDYDVAAELQLAKDLRLPYFEVYYESLVNGIHHTHHQEFLRELAQKEGCDRELDDWLK
                     SGND"
     gene            4388..4825
                     /locus_tag="VQ540_001000"
     CDS             4388..4825
                     /locus_tag="VQ540_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HET2544817.1"
                     /translation="MQIPSRFTIATHMLIIIALEGKKSKVTSDFLAASVGVNPVIIRK
                     ILSQLKKAELISVARGTGGTDIVKDLKDISLLDVYQAVECLGKTGQLFSFHDNPNPNC
                     PVGAHIHDVLDQKLERIQLTMEAELGQTSLEKVVADAESQMKD"
     gene            4893..5195
                     /locus_tag="VQ540_001001"
     CDS             4893..5195
                     /locus_tag="VQ540_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000281600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2544818.1"
                     /translation="MYLVIGIVLAFIVSFWKDNRSLWNPVLFLLSLISSYFYLSYLFY
                     KNGYENVQLAFYVFAFVLLPFLLFLSGIFLIYNGVILLKREGRSKPHYLSMLFDFY"
     gene            complement(5286..6359)
                     /locus_tag="VQ540_001002"
     CDS             complement(5286..6359)
                     /locus_tag="VQ540_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2974 domain-containing protein"
                     /protein_id="HET2544819.1"
                     /translation="MANIFDYLKDVAYDSYYDLPLNELDILTLIEITYLSFDNLVSTL
                     PQRLLDLAPQVPREPTMLTSKNRLQLLDKLAQHKRFKNCKLSHFINDIDPELQKQFAA
                     MTYRVSLDTYLIVFRGTDDSIIGWKEDFHLTYMKEIPAQKHALRYLKNFFAHHPKQKV
                     ILAGHSKGGNLAIYAASQIEQSLQNQITAVYTFDAPGLHQELTQTAGYQRIMDRSKIF
                     IPQGSIIGMMLEIPAHKIIVQSTALGGIAQHDTFSWQIEDKHFVQLDKTNSDSQQVDT
                     TFKEWVATVPDEELQLYFDLFFGTILEAGISSINDLASLKALEYIHHLFVQAQSLTPE
                     ERETLGRLTQLLIDTRYQAWKNR"
     gene            6515..7192
                     /locus_tag="VQ540_001003"
     CDS             6515..7192
                     /locus_tag="VQ540_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000548969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET2544820.1"
                     /translation="MHKILLIEDDQVIRQQIGKMLSEWGFEVVLVEDFMEVLSLFVQS
                     EPHLVLMDIGLPLFNGYHWCQEIRKISKVPIMFLSSRDQAMDIVMAINMGADDFVTKP
                     FDQQVLLAKVQGLLRRSYEFGRDESLLEYAGVILNTKSMDLHYQGQVLNLTKNEFQIL
                     RVLFEHAGNIVARDDLMRELWNSDFFIDDNTLSVNVARLRKKLEEQGLVGFIETKKGI
                     GYGLKHA"
     gene            7185..8159
                     /locus_tag="VQ540_001004"
     CDS             7185..8159
                     /locus_tag="VQ540_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HET2544821.1"
                     /translation="MLDWKQFFLAYLRSRSRLFIYLLSLAFLVLLFQFLFASLGIYFL
                     YFFFLCCFVTILFFTWDILVEMQVYRQELLYGEREAKSPLEIALAEKLEAREMELYQQ
                     RSKAERKLTDLLDYYTLWVHQIKTPIAASQLLVAEVVDRQLKQQLEQEIFKIDSYTNL
                     VLQYLRLESFHDDLLLKQVQIEDLVKEIIRKYALFFIQKGLNVNLHDLDKEIVTDKKW
                     LLVVIEQIISNSLKYTKEGGLEIYMDDQELCIKDTGIGIKNSDVLRVFERGFSGYNGR
                     LTQQSSGLGLYLSKKISEELGHQIRIESEVGKGTTVRIQFAQVNLVLE"
     gene            complement(8208..10151)
                     /gene="thrS"
                     /locus_tag="VQ540_001005"
     CDS             complement(8208..10151)
                     /gene="thrS"
                     /locus_tag="VQ540_001005"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HET2544822.1"
                     /translation="MINITFPDGAIREFESGVTTFEIAQSISNSLAKKALAGKFNGKL
                     IDTTRAITEDGSIEIVTPDHGDALPILRHSAAHLFAQAARRLFPDIHLGVGPAIEDGF
                     YYDTDNTAGQISNEDLPRIEEEMQKIVKENFPSIREEVTKDEAREIFKNDPYKLELIE
                     EHSEDEGGLTIYRQGEYVDLCRGPHVPSTGRIQIFHLLHVAGAYWRGNSDNAMMQRIY
                     GTAWFDKKDLKNYLQMREEAKERDHRKLGKELDLFMISQEVGQGLPFWLPNGATIRRE
                     LERYIVNKELASGYQHVYTPPLASVELYKTSGHWDHYQEDMFPTMDMGDGEEFVLRPM
                     NCPHHIQVFKHHVHSYRELPIRIAEIGMMHRYEKSGALTGLQRVREMSLNDGHLFVTP
                     EQIQEEFQRALQLIIDVYEDFNLTDYRFRLSLRDPQDTHKYFDNDEMWENAQTMLRAA
                     LDEMGVDYFEAEGEAAFYGPKLDIQIKTALGKEETLSTIQLDFLLPERFDLKYIGADG
                     EDHRPVMIHRGVISTMERFTAILIENYKGAFPTWLAPHQVTLIPVSNEKHVDYAWEVA
                     KKLRDRGVRADVDERNEKMQFKIRASQTSKIPYQLIVGDKEMEDETVNVRRYGQKETQ
                     TVSVDNFVQAILADIANKSRVEK"
     gene            complement(10209..10385)
                     /locus_tag="VQ540_001006"
                     /pseudo
     CDS             complement(10209..10385)
                     /locus_tag="VQ540_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166032.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like protein"
     gene            complement(10392..10532)
                     /locus_tag="VQ540_001007"
     CDS             complement(10392..10532)
                     /locus_tag="VQ540_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000422774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like protein"
                     /protein_id="HET2544823.1"
                     /translation="MELQELVERSWAIRQAYHELEVKHHDFKWTVEEDLLALSNDIGN
                     FQ"
     gene            complement(10963..11163)
                     /locus_tag="VQ540_001008"
     CDS             complement(10963..11163)
                     /locus_tag="VQ540_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001826938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2544824.1"
                     /translation="MRRFYSHLPYYLVILFFYWPLYELFLLVVSDPLTLKGLYINNLL
                     FFTPMVILIVSLLYSYRFRFSL"
     gene            11402..11947
                     /locus_tag="VQ540_001009"
     CDS             11402..11947
                     /locus_tag="VQ540_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001852743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HET2544825.1"
                     /translation="MKLAVIAANGQAGKAIVEEAVKRGHEVTAIVRSENKSQAESIIK
                     KDLFELTKDDLTGFDAVISAFGAYTPDTLPLHSKSIELFNQLLAGTQTRFLVVGGSGS
                     LYIDETKTTRLLDTPDFPEEFKSLAKAQADELDLLRTKNNLNWAFVSPAVDFIPDGEK
                     TGNYILAGEIFTTNEKRNKPD"
     gene            12173..12442
                     /gene="rpsO"
                     /locus_tag="VQ540_001010"
     CDS             12173..12442
                     /gene="rpsO"
                     /locus_tag="VQ540_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HET2544826.1"
                     /translation="MAISKEKKNEIIAQYARHEGDTGSVEVQVAVLTWEINHLNEHIK
                     QHKKDHATYRGLMKKIGRRRNLLAYLRKNDVNRYRELINSLGLRR"
     gene            13258..13872
                     /locus_tag="VQ540_001011"
     CDS             13258..13872
                     /locus_tag="VQ540_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000531723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CadD family cadmium resistance transporter"
                     /protein_id="HET2544827.1"
                     /translation="MGQTIISAIGVYISTSIDYLIILIILFAQLSQNKQKWHIYAGQY
                     LGTGLLVGASLVAAYVVNFVPEEWMVGLLGLIPIYLGIRFAIVGEDAEEEEEEIIERL
                     EQSKANQLFWTVTLLTIASGGDNLGIYIPYFASLDWSQTLVALLVFVIGIIIFCEISR
                     VLSSIPLIFETIEKYERIIVPLVFILLGLYIMYENGTIETFLIV"
     gene            complement(14164..14913)
                     /locus_tag="VQ540_001012"
     CDS             complement(14164..14913)
                     /locus_tag="VQ540_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HET2544828.1"
                     /translation="MFYTYLRGLVVLLLWSINGNAHYHNTDKIPNQDENYILVAPHRT
                     WWDPVYMAFATKPKQFIFMAKKELFTNRIFGWWIRMCGAFPIDRENPSASAIKYPINV
                     LKKSDRSLIMFPSGSRHSNDVKGGAALIAKMAKVRIMPVTYTGPMTLKGLISRERVDM
                     NFGNPIDISDIKKMNDEGIETVANRIQTEFQRLDEETKQWHNDKKPNPLWWFIRIPAL
                     ILAIILAILTIIFSFIASFIWNPDKKREELA"
     gene            15046..17382
                     /locus_tag="VQ540_001013"
     CDS             15046..17382
                     /locus_tag="VQ540_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HET2544829.1"
                     /translation="MDKNKIMGLTQREIKERQAEGLVNDFTASASTSTWQIVKRNVFT
                     LFNALNFAIALALAFVQAWSNLVFFAVICFNAFSGIVTELRAKHMVDKLNLMTKEKVK
                     TIRDGQEVALNPEELVLGDVIRLSAGEQIPSDALVLEGFAEVNEAMLTGESDLVQKEV
                     DGLLLSGSFLASGSVLSQVHHVGADNYAAKLMLEAKTVKPINSRIMKSLDKLAGFTGK
                     IIIPFGLALLLEALLLKGLPLKSSVVNSSTALLGMLPKGIALLTITSLLTAVIKLGLK
                     KVLVQEMYSVETLARVDMLCLDKTGTITQGKMQVEAVLPLTETYGEEAVASILTSYMA
                     HSEDKNPTAQAIRQRFQGQVVYPMLSNLPFSSDRKWGAMELEGLGIVFLGAPEMLLDS
                     EVPEAREALERGSRVLVLALSQEKLDHHKPQKPSDIQALALLEILDPIREGAAETLNY
                     LRSQEVGLKIISGDNPVTVSSIAQKAGFADYHSYVDCSKITDEELIALAEETAIFGRV
                     SPHQKKLIIQTLKKAGHTTAMTGDGVNDILALREADCSIVMAEGDPATRQIANLVLLN
                     SDFNDVPEILFEGRRVVNNIAHIAPIFLIKTIYSFLLAVICIASALLGRSEWILIFPF
                     IPIQITMIDQFVEGFPPFVLTFERNIKPVEPNFLRKSMLRALPSALMVVFSVLFVKIF
                     GTSQGWSELEISTLLYYLLGSIGFLSVFRACMPFTLWRVLLIVWSVGGFLATALFPRI
                     QKLLEISTLTEQTLPVYGVMMLVFTVIFILTSRYQARK"
     gene            17484..18161
                     /locus_tag="VQ540_001014"
     CDS             17484..18161
                     /locus_tag="VQ540_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000624068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HET2544830.1"
                     /translation="MISKRLELVASFVSQGAILLDVGSDHAYLPIELVERGQIKSAIA
                     GEVVEGPYQSAVKNVEAHGLKEKIQVRLANGLAAFEETDQVSVITIAGMGGRLIARIL
                     EEGLGKLANVERLILQPNNREDDLRIWLQDHGFQIVAESILEEAGKFYEILVVEAGQM
                     KLSASDVRFGPFLSKEVSPVFVQKWQKEAEKLEFALGQIPEKNLEERQVLVDKIQAIK
                     EVLHVSK"
     gene            18148..18945
                     /locus_tag="VQ540_001015"
     CDS             18148..18945
                     /locus_tag="VQ540_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000881127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HET2544831.1"
                     /translation="MLASEVIHAYEAFCPQEFSMEGDSRGLQIGTLDKGIQRVMVALD
                     IREETVAEAIEKGVDLIIVKHAPIFRPIKDLLASRPQNQIYIDLIKHDIAVYVSHTNI
                     DIVENGLNDWFCQMLGIEETTYLQETGPERGIGRIGNIQPQTFWELAQQVKQVFDLDS
                     LRMVHYQENDLQKPISRVAICGGSGQSFYKDALAKGADVYITGDIYYHTAQDMLSDGL
                     LALDPGHYIEVLFVEKIAALLTQWKEKKGWELEILPSQASTNPFRHI"
     gene            18962..20065
                     /locus_tag="VQ540_001016"
     CDS             18962..20065
                     /locus_tag="VQ540_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HET2544832.1"
                     /translation="MKKVAIIGAGIVGATAAYYLSRESDLEVTVFDHEQGQATKAAAG
                     IISPWFSKRRNKAWYKMARLGADFYVDLLADLEKSGQKIDFYQRSGVFLLKKDESKLE
                     ELYQLALQRREESPLIGQLAILDQASANELFPGLQGFDRLLYASGGARVDGQLLVTRL
                     LEASHVKLVKEKVTLTPLASGYQIGEEEFEQVILATGAWLGDMLEPLGYEVDVRPQKG
                     QLRDYQLVQDMEAYPVVMPEGEWDLIPFAGGKLSLGATHENDMGFDLTVDETLLQQME
                     EATLTHYLILAEATSKSERVGIRAYTSDFSPFFGQVPDLTGVYAASGLGSSGLTTGPI
                     IGYHLAQLIQDKELTLDPENYPIENYVKRVKSE"
     gene            20072..20263
                     /locus_tag="VQ540_001017"
     CDS             20072..20263
                     /locus_tag="VQ540_001017"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2544833.1"
                     /translation="MKIKEQTRKLAAGYSKHCFEVVDRTDEVSSKHCFEVVDRTDEVS
                     NHTHGKATLTWFELDFRRV"
     gene            20366..21385
                     /gene="galE"
                     /locus_tag="VQ540_001018"
     CDS             20366..21385
                     /gene="galE"
                     /locus_tag="VQ540_001018"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HET2544834.1"
                     /translation="MQEKILVTGGAGFIGTHTVIELIQAGHQVVVVDNLVNSNRKSLE
                     VVERITGVEIPFYEADIRDTATLRDIFKQEEPTGVIHFAGLKAVGESTRIPLAYYDNN
                     IAGTVSLLKAIEENNCKNIIFSSSATVYGDPHTVPILEDFPLSVTNPYGRTKLMLEEI
                     LTDIYKADSEWNVVLLRYFNPIGAHESGDLGENPNGIPNNLLPYVTQVAVGKLEQVQV
                     FGDDYDTEDGTGVRDYIHVVDLAKGHVAALKKIQKGSGLNVYNLGTGKGYSVLEIIQN
                     MEKAVGRPIPYRIVERRPGDIAACYSDPAKAKAELGWEAELDITQMCEDAWRWQSKHP
                     NGFED"
     gene            21387..22340
                     /locus_tag="VQ540_001019"
     CDS             21387..22340
                     /locus_tag="VQ540_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HET2544835.1"
                     /translation="MMISIIVPCLNEEEVLPLFYQALEALLPDLETEIEYVFVDDGSS
                     DGTLELLKAYREQNPAVHYISFSRNFGKEAALYAGLQYATGDLVVVMDADLQDPPSML
                     FEMKNVLDKNVDLDCVGTRRTSREGEPFFRSFCAVLFYRLMQKISPVALPSGVRDFRM
                     MRRSVVDAILSLTESNRFSKGLFAWVGFKTYYLDYPNVERQAGKTSWSFRKLFFYSIE
                     GIINFSDFPLIIAFVAGLLSCFLSLLMTFFVVVRTLILGNPTSGWTSLMAVILFLGGI
                     QLLTIGILGKYISKIYLETKKRPLYLIKEKSDDRLKKIEFI"
     gene            22492..23157
                     /locus_tag="VQ540_001020"
     CDS             22492..23157
                     /locus_tag="VQ540_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000949235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2544836.1"
                     /translation="MLSKEDYTEEIGLIKKQNYVEAELYPIVADIIKPTLKDSLSKRY
                     VFGRQRRGLGQIYYGLSNFPDIVILDKTYENKSRKSIKIEEWKKLRGCVEVKNLNYSL
                     ITEEKIKSTISNSFEHITGEMEQLTGEMGQLIGDLLWYKKVIYTNGIEWRFLSLDDKE
                     EIDNTIVEVVNKRIETEEAGNSFDWWKNIKDLSFNYTDICLSKDCRQEWNEFVKRVKE
                     IEW"
     gene            23196..23297
                     /locus_tag="VQ540_001021"
                     /pseudo
     CDS             23196..23297
                     /locus_tag="VQ540_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677122.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group 2 glycosyl transferase"
     gene            complement(23348..23554)
                     /locus_tag="VQ540_001022"
     CDS             complement(23348..23554)
                     /locus_tag="VQ540_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HET2544837.1"
                     /translation="MKITLIPERCIACGLCQTYSDLFDYHDNGIVRFYDDPDQLEKEI
                     SPSQDVLEAVKNCPTRALIGNQEA"
     gene            23606..24082
                     /locus_tag="VQ540_001023"
     CDS             23606..24082
                     /locus_tag="VQ540_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM domain-containing protein"
                     /protein_id="HET2544838.1"
                     /translation="MAKEPWQEDIYDQEESRAERRHRNHGGADRMANRILTILASIFF
                     VIVVVMVIVLIYLSSGGSNRTAALKDFHDSDASVVQISSSSSSQPEQSSEPESTSSSS
                     EEAANPEGTIKVLAGEGEAAIAARAGISIAQLEALNPGHMATGSWFANPGDVIKIK"
     gene            24091..24762
                     /locus_tag="VQ540_001024"
     CDS             24091..24762
                     /locus_tag="VQ540_001024"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HET2544839.1"
                     /translation="MKTIQIAIDGPASSGKSTVAKIIAKDFGFTYLDTGAMYRAATYM
                     ALKNQLGVEEVEALLALLDQHPISFGRSETGDQLVFVGDVDITHPIRENEVTNHVSAI
                     AAIPEVREKLVSLQQEIAQQGGIVMDGRDIGTVVLPQAELKIFLVASVDERAERRYKE
                     NIAKGIETDFETLKKEIAARDYKDSHRETSPLKQAEDAVYLDTTGLNIQEVVEKIKAE
                     AEKRM"
     gene            24893..25231
                     /locus_tag="VQ540_001025"
     CDS             24893..25231
                     /locus_tag="VQ540_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002920966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HET2544840.1"
                     /translation="MNNLPNCPKCNSEYVYEDGALLVCPECAHEWNPAEVAEVEEGLV
                     AIDANGNKLADGDTVTLIKDLKVKGAPKDLKQGTRVKNIRIVEGDHNIDCKIDGFGAM
                     KLKSEFVRKI"
     gene            25234..25863
                     /locus_tag="VQ540_001026"
     CDS             25234..25863
                     /locus_tag="VQ540_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Pr6Pr family membrane protein"
                     /protein_id="HET2544841.1"
                     /translation="MSKHYKLVFYSRIFLFLAAFTGVYLEITKHGGFGMLLYYTVLSN
                     LLVTIFTLYLLKVMSRVGENWQRPSLLRLKGGVTMSIMITCVIYHFLLAPIATNFYTL
                     ENFLCHYIVPIWFLADTLFFDKQGQYKIWDPAVWTILPFLYMMFALFNGLVLKLNIPN
                     AKDNPFPYFFLNVNKGWNVVFKWCLIIFVAYMVAGFIFYFIKQIKRKSS"
     gene            26103..27254
                     /locus_tag="VQ540_001027"
     CDS             26103..27254
                     /locus_tag="VQ540_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HET2544842.1"
                     /translation="MKQFLERASILALSLVLITSFSISSALPAMFDYYQGYSKEQIEL
                     LVSLPSFGIMMMLLLNGFLEKIFPERLQISLGLLILSLSGTAPFWYQAYPFVFGTRLL
                     FGLGLGMINAKAISIISERYQGKRRIQMLGLRASAEVVGASLITLAVGQLLAFGWTAI
                     FLAYSAGFLVLPLYLLFVPYGKSKKEVKKRAKEASRLTREMKGLIFTLAIEAAVVVCT
                     NTAITIRIPSLMVERGLGDAQLSSFVLSIMQLIGIVAGVSFSFLISIFKEKLLLWSGI
                     TFGLGQIVIALSSSLWVVVAGSVLAGFAYSVVLTTVFQLVSERIPAKLLNQATSFAVL
                     GCSFGAFTTPFVLGAIGLLTHNGMLVFSILGGWLIVISIFVMYLLQKRA"
     gene            27567..28316
                     /gene="truA"
                     /locus_tag="VQ540_001028"
     CDS             27567..28316
                     /gene="truA"
                     /locus_tag="VQ540_001028"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HET2544843.1"
                     /translation="MTRYKATISYDGYAFAGFQRQPHARSVQEEIEKTLTRLNKGQAI
                     TVHGAGRTDSGVHALGQVIHFDLPYQMDEEKLRFALDTQSPEDIDVISIELVADDFHC
                     RYAKHSKTYEFTVDRGRPKNPMRRHYATHFPYPLDVERMQIAIKKLEGTHDFTGFTAS
                     GTSVEDKVRTITEASLIVDETGQFLTFTFSGNGFLYKQIRNMVGTLLKIGNNRMPVEQ
                     IDLILEKKDRQLAGPTAAPNGLYLKEIRYEE"
     gene            28306..29079
                     /locus_tag="VQ540_001029"
     CDS             28306..29079
                     /locus_tag="VQ540_001029"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HET2544844.1"
                     /translation="MKNNRILALSGNDIFSGGGLSADLATYTLNGLHGFVAVTCLTAL
                     TEKGFEVFPTDDTIFQHELDSLRDVEFGGIKIGLLPTVSVAEKALDFIKQRPGVPVVL
                     DPVLVCKETHDVAVSELCQELIRFFPYVSVITPNLPEAELLSGQEIKTLEDMKTAAQK
                     LHDLGAPAVIIKGGNRLSQDKAVDVFYDGQTFTILENPVIQGQNAGAGCTFASSIASH
                     LIKGDKLLPAVESSKAFVYRAIAQADQYGVRQYEANKNN"
     gene            29057..29518
                     /locus_tag="VQ540_001030"
     CDS             29057..29518
                     /locus_tag="VQ540_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HET2544845.1"
                     /translation="MKQTKTTKIALVSLLTALSVVLGYFLKIPTPTGILTLLDAGVFF
                     AAFYFGSREGAVVGGLASFLIDLLSGYPQWMFFSLVNHGLQGFFAGFKGKSQWLGLIL
                     ATIAMVGGYALGSTLMNGWAAALPEILPNFMQNMVGMIVGFILSQSIKKIK"
BASE COUNT         8718 a         5367 c         6692 g         8980 t
ORIGIN      
        1 taaattttta gattgtggaa tttttttcaa cttaattctt gatttttttt ctaaattgtt
       61 atatacttaa tttacgggat aacagaatcc cgtcagaaag gggtgataat atgggaaaag
      121 agaatgttag aatgcgttta gcgtctgaat ccagacagat attagataag cttaaagatg
      181 atgtttacaa taaattaggc tatgaagtaa gctattccag tattgttagt caagctgtta
      241 gagaatacgt tcctaaaaaa gaacgtatag attggataaa attaaaagag acagctatac
      301 ctttttcatc gttaaaacag agcaataatt gggagtacca gacatcactt atgttagaga
      361 aagatgtatt aatcttactg tctgaactac aaaatttttt cttagatgtc ttccaagcga
      421 aacgtataca tagggcattt tgtatacgtc tatgtttgag agcgcaattt ttattaagta
      481 ataatgattc ttaatactat caatattaat gcggagtgta atgctccgca aaaataaaac
      541 ctattacggg ataaaaacac tactttattt aggatggaaa taagaacgta ttttttacta
      601 atattgttta gaaaggagtt tctttatgac accagaagaa caaactgctt tggaatactt
      661 ttatgaggaa ctcgagagtt acggtgaaga tgagcaagga gaggtctttg atttgtatga
      721 taattaaatc atctccatag tttctgagaa taattgagaa actatactct aaatcatagg
      781 tttatgtaaa gctagatata cacaaaagga ggtacgaatg aagatgaaag ctagagcttc
      841 accgttgaat tgattttgtt tctagaaaaa atcaataatt agaaaaatac gaggtaaaaa
      901 aatgaataga aatgtactaa attttctgcg aacagaaagt gctgaaagag ttagtcttta
      961 tatagacaag gctaatagat tggagggcga tgtaactcta ctcgcaccta gttctcaaga
     1021 tttggaagat attaaaaatg ctatgttttc caatcctaat ctcgagctaa aagtagcgag
     1081 actggatgtg atgaagaaaa tagcatatgc ttctacaaga aatcattatt taacaggggc
     1141 tacgattttt ggggatattt cgaaaggaac atacaattgt gatcctaaaa gttatgtcta
     1201 atataaggga ggttaatccc tccccttgtt tttgaaaatc gaaaggaaaa gtataaaaat
     1261 gaaagttaat gaatatttct ggagaacgag ctgtcttata ctaaaaaaga agaaatcgat
     1321 aaaatagtat acgtgttaga gatgtgtttg tcgtaaaagt ctggatagtt ttctcttagg
     1381 tagtcagctg tcatataata aaaagtagaa tggcaagcag tgatgattgg cataagagat
     1441 gaaaaacgct gagaactaat gaaggctaag agaacaaaaa atagaaaatc aatggtgaga
     1501 acccctaaat agtagaagcg aatcttttta ttgatttgag gataaatctc agcgaattga
     1561 tgtttgagtc ggacgaccaa gagaaatagc aggagtcctt gagcaaggaa gaaaattaaa
     1621 ccagagagca agagccactc aaaagatgtc tcgagtctag tgataaaaaa tgcaaatagt
     1681 agcaaatcaa taactgcaat tgctataaaa tggattctat agagtttttt catgacaaga
     1741 cctccctctt ttatctaact tcattctact ctaaaagaat gggagttaca actaaaatga
     1801 taaaaatagc agaggggaga ttctcttaag ttggctagta ttctttattt gagtttcctt
     1861 ctattatcta acttcttcat cattccagac aaataaagct ccgattgcat tgaggatata
     1921 aaagatgtat ttaccgatat tggcgaagtt tccttgaata ccagcttttg tcagctgaac
     1981 gaaattgtaa atcaaccaaa agccccactg tccctcattg ccaatgcatt caaagcattg
     2041 gcaatgaggg acagtgcaaa ggcaatagtt gttacgtagg caaggagatt catcttgccc
     2101 ccatatccga tatagttggt cacaaaggca aagaggaagg cgatgatgga aatgatgatg
     2161 gccgccaatt ttacctgttt ttggctcatt tggttgggtc tgccttcttg cgaagctttc
     2221 catttcttta tagcaaaggt ataaatgagg aaggtgacgg gataggtaat gatggccgcc
     2281 ttatttccaa ggatataatc aatagcaccg gacaaaatgg tattaacaat accaaagtaa
     2341 ttttcccatt tgcttaattt ccccgtgaaa cgagtggaca acatggaaat cccaacgttg
     2401 gttacggaaa tcaatccaaa gggtacaaga gctgtccatg gtccccagtc tacaaattta
     2461 tcgaggcgtg agttgaggta accagatgca atcgcaatcc aacgaccaaa gcaaccccga
     2521 agaggtcaaa ctatttagat gtagcaaaaa tttttagtga ttttttcata ggttaaacta
     2581 cctttctttt tttcaaatat tctcccattt tttttcaaat attctaccac caaatgaaag
     2641 taaaataaaa tgatagaaat aaaaccctga aaataaaact ttcagggttg gtaggggact
     2701 tgagaaatta gttgattttc tcgacataga gttgttttgc aatgtccata ttcacttgta
     2761 aatcctcgtc gttactgagg atagtgaagg tattgctgaa gccatcaaac tgcttaactt
     2821 ggagctggtc accgatgtga agtgagtgct tgtccagata atggagaatg tcaaaactat
     2881 cgtgcatccg agtcaggcgg taggcgccag cttccttgat atcagctagt gggaggttat
     2941 tgatttcaac gaggagttct cccttggcag gaatagttcc tccgtggggg caggttttag
     3001 ggaaacctag cagtttatct agtctttcca cgaacaggtc agagacagtg tgttccaaga
     3061 cctcagcttc ctcgtgaatc tggtcacttg tatagtctaa atgatgaact agaaaaactt
     3121 caatcaagcg gtgcttacga tagagctcag agaccagttt gagaccgagg tcagtcagta
     3181 gatagccaca ttccttgtcc tttaggatga gattttcact tttcattcgt ttgatcattt
     3241 cagttacggc agggggagag acttgcatgc gagccgcaat ttccttgttg gtaatcttat
     3301 gcaggtctat gccaatttca taaatacatt ttagatagtc ttctttgttt ggggtcattc
     3361 gtttcctctt gtctaatatc tttatctagt atatcaaaaa aagctagatt tctctagctg
     3421 tgacttttta tgttatactt attgcaagag aaaaaacgag gagatggata tgacgaaaat
     3481 agctcttctt tcagatattc atggaaatac caccgccttg gaggctgttt tggcagatgc
     3541 tcggcagcta ggagtggatg aatactggct tttgggagat attctcatgc cagggacagg
     3601 gcgtagaagg attttggact tgttggatca actaccgatt acggctagag ttttgggaaa
     3661 ctgggaagac agtctttggc atggtgtccg taaggaattg gatagtactc gccctagtca
     3721 acgctatctc ttgcgccagt gccagtatgt tttagaggaa atttccctag aagaaattga
     3781 agtgctccac aatcaacctc ttcaaattca tcgtcagttt ggggatttga cagtgggaat
     3841 tagccatcat ctgcctgata agaactgggg gcgagagttg attcatactg gcaaacaaga
     3901 ggaatttgac cgcttggtga ctcatcctcc ctgtgatatt gctgtttatg gacacattca
     3961 ccagcagttg cttcgttacg ggactggtgg gcaattgatt gtcaatccgg gttcgattgg
     4021 ccaacctttc tttttggacg ctcagctacg gaaggacttg cgggcccagt atatgatttt
     4081 ggagtttgat gacaagggcc tggtagatat ggacttccga cgggtagatt acgatgtggc
     4141 agctgaattg cagctggcta aagacctgag acttccctat tttgaggttt actatgaaag
     4201 tctggtcaat gggatccacc atactcatca tcaggaattt ttgagagaat tggctcagaa
     4261 agagggttgc gatcgggagt tagacgactg gttgaaaagt ggtaacgatt gacattacaa
     4321 ctaaaaaggg tataataata gaaaaagaag agtagaggca gggtagcctc gtaaaaagga
     4381 gaagaggatg caaattccaa gtagatttac cattgcgact catatgctga taatcattgc
     4441 cctcgagggg aagaaaagca aggtgaccag tgattttctg gctgctagtg tcggggtcaa
     4501 tcctgtcatt atcagaaaga tcttgtccca gttgaagaag gcagagctga tttcagtagc
     4561 gcgtggaacg ggcggaacag atattgtcaa ggaccttaag gatattagtc ttttagatgt
     4621 ttatcaggcg gtcgaatgtc ttggtaagac aggtcaactc ttcagtttcc atgacaatcc
     4681 gaatccaaat tgccctgtag gagctcatat tcatgatgtt ttggatcaaa aattggagag
     4741 aattcagttg actatggagg cagaacttgg tcaaaccagt ctagaaaaag tcgtggccga
     4801 tgcagagagt cagatgaagg attaagaggg ataaatgccc tcttttttct ttggataatt
     4861 atgataaaat gtagctatta aaggagtaag aaatgtatct cgttatagga attgtattag
     4921 cctttatagt gtcattttgg aaggataata gaagtttgtg gaatccagta ttatttttat
     4981 tatccctcat ttcaagttat ttttatctat cctacctttt ttataaaaat ggatacgaga
     5041 atgttcagtt agctttttat gtatttgcct ttgtcttact tccttttttg ctttttctaa
     5101 gtggcatctt tttaatctat aatggggtca ttttgttgaa gcgagaggga cgttccaagc
     5161 cccattatct ctcaatgctc tttgattttt attgactatt agattctatt taaaaagact
     5221 tagaatgcac atgaaagtat gtattctagg tcttttgttt tgtatacatt taattttcaa
     5281 gagtattatc tatttttcca tgcctggtaa cgagtatcaa tcaataactg ggtaaggcga
     5341 cccaaggttt ctctttcttc tggagtgagg gattgagctt ggacaaagag atgatgaatg
     5401 tattcaagcg cctttaagga agccaagtca ttgatagagc taataccagc ctcaagaata
     5461 gtgccaaaga agaggtcgaa gtagagctga agttcttcgt cagggactgt ggccacccat
     5521 tctttaaagg ttgtgtctac ttgctggcta tcactgttgg tcttatccag ttggacgaag
     5581 tgcttgtcct caatctgcca actaaaggta tcgtgctggg cgatgccacc cagggcagta
     5641 ctctgaacga tgattttgtg agcaggaatt tccagcatca taccgataat ggaaccttgt
     5701 ggaatgaata tcttgcttct atccattatc ctttgataac ccgcagtctg tgtcaattct
     5761 tgatggagac caggtgcatc aaatgtataa actgctgtga tctgattttg caaactttgc
     5821 tcaatttggc tagcagcata gatagcgaga tttcctccct tggaatgccc agctagaata
     5881 accttttgct taggatgatg ggcaaaaaag ttctttaaat agcgaagggc gtgcttttga
     5941 gcaggaattt ccttcatata ggtcaggtgg aaatcttcct tccagccaat gatactgtca
     6001 tctgtcccac gaaagacaat cagataggta tcgaggctga cacgataagt catagccgca
     6061 aattgctttt gcagttcagg gtcgatgtcg ttgataaaat gggagagttt gcaatttttg
     6121 aagcgcttgt gttgagccaa tttatctaat aattgaaggc gatttttgct agtaagcatg
     6181 gtgggctctc ttggaacctg aggtgctaga tctaaaagac gttgaggaag tgtggagacc
     6241 agattatcaa aggagaggta ggtgatttct attaaggtta gaatgtctaa ctcattcaag
     6301 ggaaggtcgt aataagaatc atatgcgaca tctttcagat agtcaaaaat attggccata
     6361 agagctcctt tctttttatt tatcttagca aatttccctc aaattagcta gtagcatagc
     6421 ctgtttgcac tggctaaaaa caggctattt caaattcagt ttcagaccat ctagcatgga
     6481 aaaatctgtt ataataatgg aaaaggagaa gcgcatgcac aagattttat taatagaaga
     6541 tgatcaggtc attcgtcaac agattgggaa aatgctctct gaatggggat ttgaagtggt
     6601 cctggtagaa gactttatgg aagttttgag tctatttgtt cagtcggaac ctcatctggt
     6661 cctcatggat attggtttgc ccttgtttaa tggttatcac tggtgtcagg aaatccgcaa
     6721 gatttccaag gtacctatca tgtttctttc ttcgagagac caggctatgg atattgtcat
     6781 ggcaatcaat atgggggcgg atgactttgt gaccaagcct tttgaccagc aggttctttt
     6841 agctaaggtt cagggcttgt tgcgtcgttc ctatgagttt gggcgtgatg agagtttgct
     6901 ggaatatgct ggtgttatcc tcaataccaa atccatggat ttacattatc aagggcaagt
     6961 cttgaatttg accaagaatg aattccagat tttacgcgtg ttatttgagc atgcaggcaa
     7021 catcgtagca cgtgacgacc tgatgcggga actttggaac agtgactttt tcattgatga
     7081 taataccctc tctgtcaatg tggctcgttt gcgtaaaaag ttggaggagc agggattggt
     7141 aggatttatc gagaccaaga aaggaatagg gtacggattg aagcatgctt gattggaaac
     7201 aattttttct agcctatctg cgctcccgta gtcgtctttt tatctatctg ctttctttgg
     7261 catttcttgt cttactcttt cagtttttat ttgccagtct aggaatttac ttcctctact
     7321 ttttcttctt gtgttgcttt gtaaccatct tatttttcac ttgggacata ttggtggaaa
     7381 tgcaggtcta tcgccaggaa cttctctatg gagagaggga agccaagtct cctttggaaa
     7441 tagctttagc agaaaaatta gaagcgcgtg agatggaact ctatcagcag aggtcaaaag
     7501 cagaaagaaa actgacggat ttgctggatt actatacctt gtgggtccat cagataaaga
     7561 cccccattgc agccagtcaa ctcttagttg cagaagtggt cgaccgccaa ctgaagcagc
     7621 agctagaaca ggaaattttc aaaatcgact cttataccaa cctagtttta cagtacctgc
     7681 gtttagaaag tttccatgat gatttgctct taaagcaggt tcaaattgag gacttggtca
     7741 aggaaataat tcgtaaatat gctcttttct ttattcaaaa aggcttaaat gtcaatctac
     7801 atgaccttga taaagaaatc gtgacggata aaaagtggct gctagtggtt attgagcaaa
     7861 tcatctcaaa cagtctcaag tacaccaagg aaggtggtct ggagatttat atggatgacc
     7921 aagagctttg tatcaaagat acgggaatcg ggataaaaaa cagtgatgtc ctccgagtat
     7981 ttgaacgtgg cttttcagga tacaatggcc gtttgaccca gcagtcctct ggacttggcc
     8041 tttatctatc taagaaaatt tctgaagaac tggggcacca gattcgtatc gagtctgagg
     8101 tcggaaaagg aacgacagtg cggattcagt ttgctcaagt gaacttagtc cttgagtaaa
     8161 aatagatgag aaaaagcctc cagattggag gcttttatgc tagactctta tttctcaacg
     8221 cgtgatttgt tggcgatatc agctaggata gcttgaacaa aattatcaac tgagacagtt
     8281 tgtgtttctt tttggccgta gcgacgaacg ttgactgttt cgtcttccat ttctttgtct
     8341 ccaacaatta attggtaagg aatcttgctg gtttgtgaag cacggatctt gaactgcatt
     8401 ttttcattgc gctcatctac gtctgcacgg acaccgcggt cacggagttt cttggctact
     8461 tcccaagcgt agtccacgtg tttttcgtta gatactggga tgagggttac ttggtgtggt
     8521 gccagccatg ttgggaaggc ccccttgtag ttctcaatca agatagctgt gaagcgttcc
     8581 atagttgaga taaccccacg gtggatcatg actggacggt gatcttcgcc atcagctccg
     8641 atgtatttga ggtcgaagcg ttctggcaac aagaaatcaa gttggatagt agaaagggtt
     8701 tcttcttttc caagggcagt tttaatctgg atatccaatt ttggtccgta gaaggctgct
     8761 tcaccttcgg cttcaaagta gtccacgccc atttcatcaa gagctgcacg aagcatggtt
     8821 tgggcatttt cccacatctc atcgttatca aagtacttat gagtatcttg agggtcacga
     8881 agagagaggc ggaagcggta gtcagtcaag ttgaagtctt cataaacatc gataatcaac
     8941 tgaagggcac gttggaattc ttcttggatt tgttctggag taacgaatag gtgaccgtcg
     9001 ttgagtgaca tttcacgtac acgttgaagg ccagtgaggg caccagattt ttcgtaacgg
     9061 tgcatcatac cgatttcagc gatacggatt ggcaattcac ggtaagagtg aacatggtgt
     9121 ttgaaaactt ggatgtggtg cggacagttc attggacgaa ggacaaattc ttccccgtca
     9181 cccatgtcca tggttgggaa catgtcttct tggtaatgat cccagtgacc agaagtcttg
     9241 taaagctcaa cagaagcaag tggtggagtg tagacgtgtt ggtagccaga agccaactct
     9301 ttgtttacga tgtagcgttc caattcacga cggatagtcg caccatttgg caaccagaat
     9361 ggcaaacctt gtcccacttc ttgtgaaatc ataaagaggt caagctcttt accaagttta
     9421 cggtggtcac gttccttagc ttcttcacgc atttgaaggt agtttttcaa gtctttcttg
     9481 tcaaaccaag ctgtaccgta gatacgttgc atcatagcgt tgtcgctgtt tccacgccag
     9541 tacgcaccag ctacatggag aaggtggaag atttggatac gacctgttga tggaacgtga
     9601 ggtccacggc agaggtctac atattcaccc tgacgataga tagtcaaacc gccttcgtct
     9661 tctgagtgtt cttcaatcaa ttccaacttg taagggtcat ttttgaagat ttcacgtgcc
     9721 tcgtctttag tcacttcttc acgaatagat gggaagtttt ctttgacgat tttttgcatt
     9781 tcttcttcga tacgaggaag gtcttcgtta gagatttgac cagctgtgtt gtcagtatcg
     9841 tagtagaaac catcttcgat ggctggacca actcccaagt gaatgtctgg gaaaagacga
     9901 cgagctgctt gggcgaacaa gtgagctgct gagtgacgca agattggaag ggcatctccg
     9961 tgatcaggtg tcacaatttc gatgcttcca tcttcagtga tagcgcgagt agtgtcgatg
    10021 agtttgccgt tgaatttacc agccaaggct tttttagcta gggaattgct gatagattgg
    10081 gcaatttcaa aagttgttac gccagattcg aattcacgaa tagcgccatc tgggaaagta
    10141 atgttaatca tgatgttctc cttttttatt atttcatagt ttctaagcat tgatttttta
    10201 tcagcagact acttccaagt tctaacgttc aattgctttt ctttatcaga gaggaagttt
    10261 tccatttccg tcagaatatc tatatccaaa cgttgagaaa gttctaatag tcaccagata
    10321 ttttctgaaa gtttttgttc cagtgtgtag ggtgtttcat catagtagcg tccttgcttt
    10381 gtcatcacca gtcattggaa atttccaata tcattagata aagccaagag gtcttcttct
    10441 accgtccact tgaaatcatg atgcttaact tccagttcgt gataagcttg tcggattgcc
    10501 caactgcgct ccactaattc ttgcaactcc ataattagta tcctaataaa aaaatgcgac
    10561 atcctcgaaa ggacgtcgca acgtggttcc accttcattt atgtacctca aaagagaggg
    10621 acacctctga tcggctctaa cgtggccacc gttttatgtt ttcataaaaa actcaagagt
    10681 agtatcagtt tagacttcct atgcgtttcc agcaaccacg cactctctag tagaaaggga
    10741 ctaagtgact tgtctctatg gattattata gcatgattgt gagatttttc aaggattttg
    10801 tgaaagtttt ttgtttttca ttttttgtag aatatgcttg atgctaatac cagaatccat
    10861 gcccaccaga gcaactgttt catagattag caagtaaatt agtataaaca caccaaaggt
    10921 tatgatagta aagtaaaaga gcagtccgtt accaactaac catcaaagtg agaaacggaa
    10981 acggtagcta tagagtaacg atacaatcaa gattaccata ggtgtaaaga agagaagatt
    11041 gtttatatag agtcccttga gtgtaagggg gtcagaaaca actagcaaga acaactcata
    11101 aagtggccaa taaaagaata atatgaccag atagtagggg agatgggaat agaatctacg
    11161 catgataatc acctcgtttt aaaaaaacag acaacttaga tctcttgcta tgattattat
    11221 agtatgttta aaacaagaaa gtaaatttgt tgacaaagaa gatttttctt ttcactagaa
    11281 tcatggttag ttttcttggt agaaatattt tgataataat taagcaagac tattgacatt
    11341 gattattaag agtgtcacaa ttgttgtaac taaaataatt acaacaagag gggtataaaa
    11401 aatgaaacta gcagttattg cagcaaatgg acaagcgggg aaggcaattg ttgaagaagc
    11461 agtcaaacga ggacatgaag taacggctat tgttcgttct gaaaacaaaa gtcaagctga
    11521 gtctattatt aaaaaagatt tatttgagtt gacaaaagat gatcttactg gatttgatgc
    11581 tgttatttca gcgtttggtg cttatacacc agatacgcta ccgctccaca gcaaatcaat
    11641 cgaactattt aatcagcttc ttgctggaac acagacacgt tttctagttg tagggggatc
    11701 aggaagcctt tatatagatg aaacaaaaac gacacgactt ttagatacgc ctgattttcc
    11761 tgaagaattt aagtcactag caaaagctca agcggatgaa ttggatcttc ttcgtacaaa
    11821 aaataatctc aactgggctt ttgtcagtcc tgctgtagat tttattcccg atggtgaaaa
    11881 aacaggaaac tacattctag caggagaaat ttttactact aatgaaaaaa ggaataagcc
    11941 agattagtta tgcagattat gctattggat tggtagatga acttgaaaaa ggtcatcata
    12001 taaaagaacg tatctcttta cttgaaaaat aataactatg agagtattaa tgtttgacag
    12061 aaaatttaaa tcttggtaga atagggattg tcgtaaagac aaataacttc ttcttggtta
    12121 caggcatgcc aacctgtcac tcggatgaag ccaaataaaa aggagaaaca tcatggcaat
    12181 ctcaaaagag aaaaaaaatg aaatcatcgc acaatatgca cgtcacgaag gtgatacagg
    12241 ttcagtagag gttcaagttg ctgtccttac ttgggaaatc aaccacctta atgaacacat
    12301 caaacaacac aaaaaagacc acgctactta ccgtggattg atgaaaaaaa tcggtcgccg
    12361 tcgtaacttg cttgcatact tgcgtaaaaa cgacgttaac cgttaccgtg agttgatcaa
    12421 ctctctagga cttcgtcgct aattcaagat acaaaggctg tcaaaagcac aaagtaaaaa
    12481 taggaaaatt tacgaagaaa cttcagtttc taggagattt tatctttttt gccaagtgct
    12541 taggccgtgt tcaattgagc atatcttgat aatgaagcta ctctaaattg ggtagctttt
    12601 ttgtgttgtc accttacctc gatatactca agtataatct ttggttacgg ttcctagcac
    12661 tgtaaggtaa aataaaccag cttttctccc ttcggggaga ttttttttgt ttcactgaaa
    12721 gtttcgtacg atcttcgcct cgtcgcctag tctataaacg atttatctag caagaatcat
    12781 gatgctaagg gcgtcaaaaa tccgtatgaa aatagggaaa tgacacagtg ttcgatgagc
    12841 acaaggagtt tcatcttttt cactaggatt ttagcccgga ctcaaatcag ctctctgact
    12901 tcagagggct tttttattga ggttttatcg gtaacaattt tggagactac aaaaacctca
    12961 aacggtatca gctaattaca ccataaaggt gcgcagttac tcggcttttc aagccgagta
    13021 gttgtatgca agccccctag aagagcccac tctttacaaa gtaaagtata gtatgttata
    13081 ctttacatgg aagtagtcac tgaattccag ttagaaatta ctttgtaact acgttttgag
    13141 gaggagtaaa atgctttcct acgttcgata ttacccacta gcgatagcta aattaatgtg
    13201 tctgtgctct cctaaaatct gctgatttat tactgactaa tacaggagtt tttttttatg
    13261 ggacagacaa tcatatctgc tattggtgtt tatatttcca ccagtatcga ttatttaatt
    13321 attttaatta ttttatttgc acagctatca cagaataaac agaaatggca tatttatgcg
    13381 gggcaatatc taggcacagg cttacttgta ggggcgagtt tagttgctgc ttatgtcgtt
    13441 aatttcgtgc ctgaagaatg gatggttgga ttgcttggtt taatccctat ctatttaggg
    13501 attcgctttg caattgttgg agaagatgcg gaagaagaag aggaagaaat tattgaaaga
    13561 ttagaacaaa gcaaggcaaa tcaactgttt tggacagtta cattgctgac aattgcgtct
    13621 ggcggagata atttaggtat ctatatacct tattttgctt cgttagattg gtcacagacc
    13681 ctcgtggcct tgcttgtgtt tgtaatcggc ataattatct tttgcgagat tagtcgggtg
    13741 ttatcttcta ttccgttaat attcgagaca attgaaaaat acgagcgaat cattgtgccc
    13801 ttagtattca ttctacttgg actatacatc atgtatgaaa atggcacgat agagactttt
    13861 ctgatcgtgt agattttttt gtttcactag gattttagtc cgagctcaaa tcagctctct
    13921 gattttcaga gggctttttc attgagtata aatggacaat cttaaagtta ctctattgta
    13981 gagtggcttt tgatttgatt aggagattct tataaatata gtaaaatgaa ataagaatag
    14041 gacaaatcga tcaggacagt caaatcgatt tctaaaaatg ttttagaagt agaggtgtac
    14101 tattctagtt tcaatttgat atataaatga aaaccttagc tgtttggcca aggttcattt
    14161 cttctatgca agttcttctc ttttcttatc tgggttccag atgaagcttg cgataaagct
    14221 aaagatgatg gttaggatag cgagaataat agcaaggatg agggcaggga tgcggataaa
    14281 ccaccagagt ggatttggtt ttttatcatt gtgccattgt ttcgtttctt cgtccagacg
    14341 ttggaattct gtttgaatac gattggcgac tgtttcaatg ccttcatcat tcattttctt
    14401 gatatctgag atatcgattg gatttccaaa gttcatatcg acacgttcac ggctaatcaa
    14461 gcccttcaaa gtcatgggac cggtgtaggt aaccggcatg atacggacct tggccatttt
    14521 ggcaatcagt gctgcgcccc ccttgacatc gtttgagtgg cggctaccac ttggaaacat
    14581 gatgagagag cggtcacttt ttttgagaac gttgatagga tatttgatgg ctgaggcgct
    14641 gggattttca cggtcgatgg gaaaggcgcc acacatacga atccaccaac caaagatacg
    14701 gttggtaaag agttcttttt ttgccataaa gatgaactgt tttggcttgg tcgcaaaggc
    14761 catataaaca ggatcccacc aggtacggtg aggcgcaact aaaatataat tttcatcttg
    14821 attaggaatt ttatcagtat tatgatagtg agcattgcca ttgatggacc ataagagcaa
    14881 tacaactaat ccacgcaaat aagtataaaa catgcgatct ccttcgattg ttttcttgtt
    14941 attattatac cttatcaaag gagggctggc aaacttttcc cttgactaga tgcatatttg
    15001 ggatgaaatt agaattctgt taaaaaaaat gatataatag aatttatgga taaaaataag
    15061 attatgggat taacccaaag agaaatcaag gaaagacagg ctgagggttt ggtcaatgac
    15121 tttaccgcat cagccagtac cagcacttgg caaatcgtta aacgaaatgt ctttaccctt
    15181 tttaacgctt tgaactttgc cattgctttg gcccttgcct ttgtgcaggc ttggagcaat
    15241 ctggtcttct ttgctgttat ctgctttaac gctttttctg ggattgtgac cgagctacga
    15301 gccaaacaca tggtggacaa gctcaatctc atgaccaagg aaaaggtcaa aaccatccgt
    15361 gatggtcagg aagttgctct taatcctgaa gaattagtgc taggagatgt cattcgtttg
    15421 tctgcaggag agcagattcc tagtgatgcc ttggttttgg aaggctttgc ggaagtcaat
    15481 gaagccatgt taacgggaga aagtgatttg gtgcaaaagg aagttgacgg cttacttttg
    15541 tcaggaagtt tcctagccag tgggtcagtt ttatctcaag ttcaccatgt cggtgcagac
    15601 aactatgctg ccaaactcat gcttgaggct aagaccgtta aacccatcaa ctcccgtatc
    15661 atgaaatcgc tggacaagtt ggctggtttt actgggaaga ttatcattcc ctttggtctg
    15721 gctctcttgc tggaagcctt gcttttaaaa ggcctgcctc tcaagtcatc cgttgtaaac
    15781 tcgtcgacag ctcttttggg aatgttgcct aagggaattg cccttttgac cattacttcg
    15841 ctcttgactg cagtgattaa gttgggcttg aaaaaggtct tggtgcagga gatgtactct
    15901 gttgagacct tggcgcgcgt ggatatgctc tgtctggaca agacgggtac catcacccaa
    15961 ggaaagatgc aggtggaggc tgttcttcca ctgacggaaa cttatggtga agaggctgtt
    16021 gccagcatcc tgaccagcta tatggcccat agtgaggata aaaatccaac agctcaagcc
    16081 attcgccaga gattccaagg tcaagtagtc tatcctatgc tctctaatct tcccttctcc
    16141 agcgaccgca agtggggagc catggagtta gaaggtttgg gaatagtttt cttaggggca
    16201 cctgagatgt tgctggattc tgaggtccca gaagccagag aggccttgga gagaggatca
    16261 cgtgtcttgg tcttagctct cagtcaggag aaattagacc atcacaaacc acagaaacca
    16321 tctgatattc aggctctagc cttgctggaa atcttggatc ctattcgaga gggagcggca
    16381 gagacgctga actatctccg ttctcaggaa gtggggctca agattatctc tggtgacaat
    16441 ccagttacgg tatccagcat tgcccagaag gctggttttg cggactatca cagctatgtc
    16501 gattgttcaa aaatcacgga tgaggaattg attgctctgg cggaggagac agcgattttc
    16561 ggacgtgttt cccctcatca aaagaaactc attatccaaa cgctgaaaaa agcgggtcat
    16621 acaacagcta tgactgggga tggagttaat gatatcctgg ctcttcgtga ggcggattgt
    16681 tctatcgtaa tggcggaggg agacccggca acccgtcaga ttgccaacct ggttctcttg
    16741 aactcagact ttaatgatgt tcctgagatt ctttttgaag gtcgtcgtgt ggtcaataac
    16801 attgcccaca tcgctccgat tttcttgata aagaccatct attccttcct gttagcagtc
    16861 atctgtattg ccagtgcttt actaggtcgg tcagagtgga ttttgatttt ccccttcatt
    16921 ccgatccaga ttaccatgat tgaccagttt gtggaaggtt tcccaccatt cgttctgact
    16981 tttgagcgaa atatcaaacc tgttgagcca aatttcctca gaaaatccat gcttcgtgcc
    17041 ctaccaagtg ccctcatggt cgtgtttagc gttctttttg tgaaaatctt tggaacgagt
    17101 caaggttggt ctgagttaga aatctcaact ctcctctatt atctcttggg gtcaattggt
    17161 ttcttatccg tatttagagc ctgcatgcca ttcactctat ggcgagtcct cttgattgtc
    17221 tggtcagtag gaggcttcct agccacagct ctcttcccaa gaatccaaaa actgcttgaa
    17281 atttcaacct tgacagaaca aacgttgcct gtttatggtg tcatgatgtt ggtctttaca
    17341 gtgattttca tcctgactag tcgctatcaa gctagaaaat aaagaaagac tgcaatctgt
    17401 ggattgcagt ttttttaggt acaagattgc cagccgaaat gtggtataat aagaggtaat
    17461 agagttttgg aaagtgagag aagatgattt caaagagatt agaattggta gcttcctttg
    17521 tgtcacaggg ggctatttta ctagatgtgg gaagtgacca tgcttatctg cctatcgagt
    17581 tggttgagag aggccaaatc aaaagcgcta ttgcaggtga ggtggtggaa ggtccctatc
    17641 agtctgcggt taaaaatgtt gaggctcacg gcctaaagga gaaaatccaa gtccgtttag
    17701 ccaatggctt ggcagctttt gaagagactg accaagtgtc tgtcattacc attgctggca
    17761 tgggtggtcg tttgattgct aggattttag aagaaggttt ggggaagtta gctaatgtag
    17821 agcgtttgat cctccagccc aataatcgtg aagacgactt gcgtatctgg ctacaggatc
    17881 atggattcca gattgtagca gaaagcatct tagaagaagc tggaaagttt tatgagattt
    17941 tggtggtgga agcaggacaa atgaagctat cagccagtga tgttcgcttt ggtcccttct
    18001 tgtccaaaga agtcagtcca gtatttgtcc aaaaatggca aaaagaagct gagaagctag
    18061 agttcgctct cggacaaatc ccagaaaaaa atctggaaga acgtcaagtt ctagtagata
    18121 agattcaagc tatcaaggag gtgctccatg ttagcaagtg aagtgattca tgcttatgaa
    18181 gccttttgcc ctcaggaatt ttctatggag ggagacagcc gtggtctgca aattggcact
    18241 ttagacaagg gtatccaaag ggtcatggtt gccctcgata ttcgtgaaga gacagtggca
    18301 gaggccattg aaaagggtgt ggacttgatt atcgtcaagc acgcgcctat ctttcgtcct
    18361 atcaaggact tgcttgccag ccgtccgcaa aatcagattt acatcgacct gattaagcat
    18421 gacatcgcag tttatgtcag ccataccaat attgatatcg ttgaaaatgg gctcaatgac
    18481 tggttttgtc agatgctagg aatcgaggag acgacttatc tgcaggaaac aggtccagaa
    18541 cgtggaattg gacgtattgg gaatattcag cctcagacat tttgggaatt ggcccaacag
    18601 gtcaagcaag tctttgacct agatagcctt cgaatggtgc attatcaaga gaatgatttg
    18661 cagaagccta tttcaagagt agcaatttgt ggtggaagcg ggcagtcttt ctataaggat
    18721 gctttggcaa agggggcaga tgtctatatc actggtgata tctactacca tactgctcag
    18781 gatatgctgt ctgatggctt gttagcattg gatccaggtc actatatcga agtgcttttt
    18841 gtggaaaaaa tcgcagcact ccttactcaa tggaaagaga aaaaaggctg ggaactagag
    18901 attttaccta gtcaagcatc gaccaatcct ttccgtcata tctagttaga aagtgaagac
    18961 aatgaaaaaa gttgccatta ttggagcagg aattgtggga gcaacagctg cctactacct
    19021 ctcgagagaa agtgacctag aggtgaccgt ttttgaccat gagcaaggtc aagccaccaa
    19081 ggccgcagca ggaattatca gtccttggtt ttccaaacgc cgtaataaag cctggtacaa
    19141 gatggcgcgc ttgggggctg atttttatgt ggatttatta gctgatttag agaaatcagg
    19201 acaaaaaatc gacttttacc agcgttcggg agtctttctc ttgaaaaagg atgaatccaa
    19261 gttggaagaa ctttatcaac tggccctcca gcgcagagaa gaatctccct tgatagggca
    19321 attagccatt ctggaccaag cctcagctaa tgaattattc cctggtttgc agggatttga
    19381 ccgcctgctc tatgcttctg gtggagcgag agtagatggc caactcttgg taactcgtct
    19441 gctagaagcc agtcatgtca agctggtcaa agaaaaagtg actctgacac cgttagcatc
    19501 aggctaccag attggtgaag aggagtttga gcaggttatt ttggcgacgg gagcttggtt
    19561 gggggacatg ttagaaccct tgggttatga agtagatgtt cgtcctcaaa aaggacaact
    19621 acgagattat cagctggtcc aagacatgga agcttaccct gttgtcatgc cagaagggga
    19681 gtgggatttg attccttttg caggtgggaa attgtcctta ggcgctaccc acgaaaatga
    19741 catgggattt gatttgacgg tagatgaaac cttgctccaa caaatggagg aggccacctt
    19801 gactcactat ctgattttgg ctgaagctac ttcaaaatct gagcgtgttg gaatccgtgc
    19861 ctacaccagt gatttctctc ctttctttgg gcaggtgcct gacttaactg gtgtctatgc
    19921 agccagtgga ctaggttcat caggcctcac aactggtcct attattggtt accatttagc
    19981 tcaactgatc caagacaagg agttgacctt ggaccctgaa aactacccaa ttgaaaacta
    20041 tgtcaaacga gtaaaaagcg aataatactc aatgaaaatc aaagaacaaa ctaggaaact
    20101 agccgcgggt tactcaaagc actgctttga ggttgtggat agaactgacg aagtcagctc
    20161 aaaacactgt tttgaggttg tagatagaac tgacgaagtc agtaaccata cccatggcaa
    20221 ggcgacgttg acgtggtttg aattggattt tcgaagagta taagcatttt actgaaattt
    20281 tatcaggtag tttaggatgg caaatgacat tccctgtcaa aaatggtaaa ataagaaaaa
    20341 ataatctgag aatcgaggaa aaaagatgca agaaaagatt ttggtaactg gtggtgccgg
    20401 ttttattgga acccacactg ttattgaatt gatccaagca ggccatcaag ttgttgtggt
    20461 ggataatctt gtcaatagca atcgtaagag tttagaagtt gttgaaagaa tcacaggagt
    20521 tgagattcct ttctatgagg cagatattcg tgacacagct accctcagag atattttcaa
    20581 gcaggaagaa ccgactggtg tcattcactt tgctggtttg aaggctgttg gcgaatcaac
    20641 acgtatccct cttgcctact atgacaacaa tatcgctgga actgtcagcc ttttgaaagc
    20701 catagaagaa aacaactgta aaaacatcat cttcagttct tctgcgacag tttacgggga
    20761 tccgcacaca gtgcccatct tggaagattt cccactttca gtgaccaacc catacggtcg
    20821 tactaagctc atgctagagg aaattttgac tgatatttac aaagcagact cagaatggaa
    20881 tgttgtcttg cttcgttact ttaacccaat cggagcccat gagagtggtg atttgggaga
    20941 aaatccaaac ggtattccaa acaatctctt gccatatgtg actcaagtag ccgttggaaa
    21001 attagagcaa gtgcaagtgt ttggagacga ttacgatacg gaagatggaa caggtgttcg
    21061 tgactatatc cacgttgtcg atttggctaa gggtcacgtt gcagctttga aaaaaatcca
    21121 aaaaggttca ggactaaacg tttataacct tggaactggt aaaggttact cagttcttga
    21181 aattatccaa aacatggaaa aagcggtggg acgtcctatt ccttaccgta tcgtagaacg
    21241 tcgcccaggt gatatcgctg cctgctactc agacccagca aaagctaaag cagaactcgg
    21301 ttgggaagca gaactcgaca tcacccaaat gtgtgaagac gcatggcgtt ggcaaagcaa
    21361 gcatccaaat ggatttgaag actaagatga tgatttcaat catcgtccct tgtttaaacg
    21421 aagaggaagt acttcctctt ttttatcagg ctctggaagc tttacttcca gatttggaaa
    21481 cagaaatcga gtatgtcttt gtcgatgatg gatcaagtga tgggaccttg gaactcttaa
    21541 aggcctatcg ggagcaaaat ccggcagtcc attatatttc tttctctcga aattttggca
    21601 aagaagcagc cctttatgca ggcttgcaat atgcgacagg agatttggtg gtggtgatgg
    21661 atgcagacct ccaagatcct cctagtatgt tgtttgagat gaaaaatgta ctagacaaaa
    21721 atgtagactt ggactgcgtt gggacacgga gaactagtcg ggagggagaa cccttctttc
    21781 gcagtttctg tgctgttctc ttttatcgcc tcatgcaaaa aatcagccca gtggctctgc
    21841 cgtcgggtgt ccgtgatttt cgtatgatga gaaggtctgt agtcgatgcc attttaagct
    21901 tgaccgagtc caatcgtttt tcaaaggggc tcttcgcctg ggtgggtttc aaaacctact
    21961 atttggacta tccaaatgtc gaaaggcagg ctggcaagac cagttggagt tttaggaaac
    22021 tctttttcta ctccattgaa gggattatta atttttcaga ttttcccttg attatagcct
    22081 ttgtagctgg tctcctatct tgttttcttt ctctgctgat gacctttttt gttgtggttc
    22141 ggaccctcat tttgggcaat ccgacatctg gttggacctc tctgatggct gttattctct
    22201 ttcttggagg cattcaactc ttgaccattg ggattctcgg caagtatatc agtaagattt
    22261 atttagagac taaaaaaaga ccactttatc ttatcaaaga aaaaagtgat gataggctaa
    22321 aaaagataga atttatctga catagtcact ttttgttatt tgtaattctt ttagttcgga
    22381 gtttgggtga tttttaaaag aattagggat ttgaaatgat ttaaaaaatc tatgtagact
    22441 aaatttaaat tgtagtgact taataaataa aaaatttagg agtattatgt tatgctaagt
    22501 aaagaggatt atactgaaga aatcgggcta ataaagaaac aaaattatgt agaggctgaa
    22561 ttgtatccta tagttgctga tataattaag ccaactttaa aagatagttt atcaaaaaga
    22621 tatgtcttcg gaagacaaag aaggggtttg ggacaaattt attatggtct aagtaatttt
    22681 cctgatatag ttattttaga taagacttat gaaaacaaat ctaggaaaag tataaaaatt
    22741 gaagaatgga agaaacttcg aggatgcgtg gaagttaaga atttaaatta tagtttaatt
    22801 acagaggaaa aaatcaaatc aaccatatcg aacagttttg aacatataac tggagagatg
    22861 gaacaactaa ctggagagat gggacaactt attggagacc ttttatggta taaaaaagta
    22921 atttatacaa atggaattga atggagattt ctaagtttag atgacaagga agagatagat
    22981 aatacaattg ttgaagtagt taacaaaaga atagaaacag aagaagcggg aaattctttt
    23041 gattggtgga agaatattaa agatttatcg ttcaattata cggatatatg cctatctaaa
    23101 gattgtagac aagagtggaa tgaatttgta aaaagggtaa aggaaataga atggtagaag
    23161 tctattctca ttgagaaatt tagattttaa gttacagtaa gatttattta gagactaaaa
    23221 aaagaccact ttatcttatc aaagaaaaaa gtgaccttcc tgattttaca gaaaaaaata
    23281 aagtgaaaag actataattt tacatggaaa tgtgctaaac tagagggagt ggattatcgc
    23341 cattgattta ggcttcctgg tttccaatca gggcgcgagt tgggcaattt ttaacagcct
    23401 ctaagacatc ctgactagga gaaatttctt tttccagttg gtcagggtca tcgtaaaaac
    23461 gcacgattcc attatcgtgg taatcaaata aatcagaata agtttggcaa agcccacagg
    23521 cgatacatcg ttcaggtata agtgtgattt tcatgttcat atttatattg taataagaaa
    23581 agtaaaaaaa aacaaggagt aaggtatggc aaaagaaccg tggcaagaag atatctatga
    23641 tcaagaagaa tcaagagcag agcgtcggca tcgaaaccac ggaggggctg ataggatggc
    23701 taatcgtatt ttgacgatcc tagctagtat tttctttgta attgtggtgg tgatggtcat
    23761 cgttctcatc tatctatcat cggggggaag taatcgcaca gcagccttaa aagactttca
    23821 tgattctgat gcaagtgtag tacaaatctc atcttcaagc agttctcagc ctgagcagag
    23881 ttcagagcca gaatctactt ctagtagttc agaagaagct gctaatcctg aaggaacgat
    23941 taaagttctc gcaggagaag gggaagcagc tattgccgct cgtgcaggaa tctccattgc
    24001 tcagttagag gccttgaatc ctgggcacat ggctacagga tcttggtttg ctaatccagg
    24061 tgatgttata aaaataaaat aggagccgat atgaaaacaa ttcaaattgc tattgatggt
    24121 cctgcttcca gcggtaagag tacggtcgca aagattattg ctaaggattt tggattcacc
    24181 taccttgata caggagctat gtatcgtgca gcgacctata tggctcttaa gaaccaatta
    24241 ggagttgaag aagtcgaagc ccttctagcc ttgttggacc agcatccaat cagctttgga
    24301 cgttcagaaa ctggagacca gcttgttttt gtaggagatg tggatattac ccatcctatc
    24361 cgtgaaaatg aagtgaccaa tcatgtttct gctattgcag caattcctga agtgcgtgag
    24421 aaactggttt ctctccaaca agaaattgcc cagcaaggcg ggattgtcat ggatggtcgc
    24481 gatattggaa ctgttgtatt gccacaagca gaattgaaaa ttttcctagt agcttctgtt
    24541 gatgagagag cagagcgtcg ttacaaggaa aatattgcca agggaattga aacagacttt
    24601 gaaaccctaa aaaaggaaat tgctgcgcgt gactacaagg atagtcatcg tgagacttct
    24661 cctctcaaac aagcagagga tgctgtctac cttgatacaa ctggtttgaa cattcaagaa
    24721 gtagttgaaa aaatcaaagc agaagctgaa aaaagaatgt aaatgtagaa aagccgatag
    24781 attgatatcg gtttttttct aaatttgtca aaatgctgat tttagggtat aatagttgct
    24841 gttcgagaaa ttttgatttt caaagaatag tgaatgatga taaggagaaa ccatgaacaa
    24901 tttaccaaat tgtccaaaat gtaactcaga gtatgtctac gaagacggtg ccctactggt
    24961 ttgcccagag tgtgctcatg agtggaatcc tgctgaagtt gcagaagtag aagaaggtct
    25021 tgtcgctatc gatgccaacg gaaataaatt ggctgatggt gatacagtaa ctctcatcaa
    25081 ggacttgaaa gtaaaaggtg cgccaaaaga tttgaaacaa gggacgcgcg tgaaaaatat
    25141 ccgcatcgta gaaggcgacc acaatatcga ctgtaagatt gatggttttg gtgccatgaa
    25201 acttaaatca gagtttgtga ggaagattta agcatgtcaa aacactataa acttgtattt
    25261 tatagccgta tcttcttgtt tctagcggct tttacgggag tttatcttga aattactaag
    25321 catggtggtt ttgggatgct tctctattac acggttctgt ccaacctctt ggtaactatt
    25381 tttacccttt atcttctaaa ggttatgagc cgtgtaggtg aaaattggca aaggccaagt
    25441 ctcttgcgct taaaaggtgg ggtcaccatg agtatcatga ttacctgtgt gatttaccat
    25501 ttcctcttgg cgcccattgc gactaatttc tataccctag aaaatttcct ttgccactat
    25561 atcgttccca tctggttttt agcggatacc ctcttttttg acaaacaggg tcaatacaag
    25621 atttgggatc cagcagtgtg gaccatttta ccctttctgt atatgatgtt tgctcttttt
    25681 aatggcttgg ttctaaaact caatattcca aatgccaagg ataatccttt cccttacttc
    25741 tttttgaatg tgaacaaggg ttggaatgtt gtgtttaagt ggtgtctgat tatctttgtt
    25801 gcctatatgg tagcaggatt tattttctac tttatcaagc aaatcaagag aaagtcatcc
    25861 taatactctt cgaaaatctc ttcaaaccac gtcagtttcc atctgcaacc tcaaaacact
    25921 gttttgaaca acctgcggct agcttcctag tttgctcttt gattttcatt gagtataaga
    25981 tacaagggat tcattttcga atttaagaag gagtctacaa accaatgagg cttcttcttt
    26041 tcttgcttat ttgataacta tcaaaaaagt agaagattaa gagaaatata gaaagagatt
    26101 tcatgaaaca atttttagaa cgggccagca ttttggctct ctccctcgtt ttgattacct
    26161 ccttttccat ttcgagtgcc ctaccagcca tgtttgacta ttatcagggt tattctaagg
    26221 aacaaattga gctcttggtg agcttgcctt cctttggaat catgatgatg ttactgctaa
    26281 atggtttctt agaaaaaata tttcctgagc gcttacagat tagtttgggc ttgctgattt
    26341 tatcattgag cggtacagct cccttctggt accaagccta tccctttgtc tttggaacac
    26401 ggcttctctt tggtttgggt cttgggatga tcaatgccaa ggccatttct attatcagtg
    26461 aacgctacca aggaaaaagg cgaattcaga tgttagggct acgcgcttct gcagaggtcg
    26521 ttggagcttc tctcattacc ttggccgtcg gtcagttgtt ggcctttggt tggacagcta
    26581 tctttctagc ctatagtgct ggatttttgg tgctgcccct ttatctgctc tttgtccctt
    26641 atggaaaatc aaagaaagaa gtcaagaaaa gagcgaagga agcaagtcgt ttaactcgag
    26701 aaatgaaagg cttgattttt accttagcta tcgaagcggc agttgtagtt tgtaccaata
    26761 cagctattac catccgtatt ccaagtttga tggtggaaag aggattgggg gatgcccagt
    26821 tatctagttt tgttcttagt atcatgcagt tgatcgggat tgtggctggg gtgagttttt
    26881 ctttcttgat ttctatcttt aaagagaaac tgctcctctg gtctggtatt acctttggct
    26941 tggggcaaat cgtgattgcc ttgtcttcat ccttgtgggt ggtagtagca ggaagtgttc
    27001 tggctggatt tgcctatagt gtagtcttga cgacggtctt tcaacttgtc tctgaacgaa
    27061 ttccagctaa actcctcaat caagcaactt catttgctgt attaggctgt agtttcggag
    27121 cctttacgac cccatttgtt ctaggtgcaa ttggcttact aactcacaat gggatgttgg
    27181 tctttagtat cttaggaggt tggttgattg taatctctat ctttgtcatg tacctacttc
    27241 agaagagagc ttaggattga ttcctaagtt tttcttttga tactcaatga aaatcaaaga
    27301 gcatagttga ttgagtttgg aatagtacgc tgtagctgct aaaatatttc tagaaattaa
    27361 tttgactttt ctaatagagt tattcatatc ttatttcaat ctactataga aagctagccg
    27421 caggttgctc aaaatagtgt tttgaggttg cagatggaaa ctgacgtggt ttgaagagat
    27481 tttcgaagag tatgagattt ttatacccat acaatatttg ttttaggtcc ttgtttacag
    27541 actaatttct tgataaaata gaggttatga cgagatataa agcaactatt tcctatgatg
    27601 gttatgcctt tgctggcttt cagcgccagc ctcatgcgcg tagcgttcag gaagaaattg
    27661 aaaaaacctt gaccagatta aataaagggc aagccattac tgttcacggt gctggtagga
    27721 cagatagtgg ggttcatgcc ctgggacagg tcattcattt tgacctgcct tatcagatgg
    27781 atgaggagaa actccgtttt gccttggata cccagtctcc tgaagatatt gatgtgattt
    27841 cgattgagct tgtggcagat gattttcatt gccgttatgc caagcatagc aagacctatg
    27901 agtttactgt ggatagagga cgtcccaaaa atccgatgcg ccgtcactat gccacccact
    27961 ttccctaccc actcgatgtg gaacgaatgc agattgcaat caaaaagcta gagggaaccc
    28021 atgattttac cggttttaca gcctctggga ctagtgtaga ggataaggtt cgcaccatca
    28081 cagaagctag tttaatagtc gatgagacag gacaattttt gacctttacc ttttcaggaa
    28141 atggtttctt gtataaacag attcgcaata tggtggggac tcttctcaaa atcggtaaca
    28201 accgcatgcc agtagagcag attgatctca tcttggagaa gaaggacagg caacttgcag
    28261 gtcccactgc agcaccaaat ggtttgtatt taaaggagat tcgttatgaa gaataatcgt
    28321 attttagcac tttctggaaa tgatattttt agtggtggtg gactgtcagc tgatttggct
    28381 acctatacct tgaacggctt gcatgggttt gtagcagtga cttgtttgac agccttgaca
    28441 gaaaaaggat ttgaagtctt tccaactgat gataccattt ttcaacatga attagatagc
    28501 ttgcgtgatg tggaatttgg gggaattaag attggtcttc tccctactgt cagtgtggct
    28561 gagaaggcct tggactttat caaacaacgc ccaggagtac ctgtggtgtt ggatcctgtc
    28621 ttggtctgca aggaaacgca tgatgtagct gtcagtgagc tctgccaaga gttgattcgc
    28681 tttttccctt atgtcagtgt gattacgcct aatctcccag aagcagaatt attatccggt
    28741 caggaaatta aaaccttgga agacatgaaa actgcagcgc agaaattgca tgatttagga
    28801 gcgccagcag tcattatcaa gggaggcaat cgtcttagtc aggacaaggc tgtggatgtc
    28861 ttttatgatg gacagacctt tactatccta gaaaatccag ttatccaagg ccaaaatgct
    28921 ggtgcaggtt gtacctttgc ctctagcatt gccagtcact tgattaaagg tgataaactt
    28981 ttgccagcag tagaaagctc taaggctttc gtttatcgtg ctattgcaca agcagatcag
    29041 tatggagtaa gacaatatga agcaaacaaa aacaactaaa atcgcccttg tatccctatt
    29101 aaccgccctt tctgtggttc taggttattt cttaaaaatc ccaacaccta caggaattct
    29161 aactctttta gatgctggtg tcttctttgc ggccttttac tttggtagtc gtgaaggagc
    29221 ggtagtcgga ggactagcaa gtttcttgat tgacctctta tcaggctacc ctcagtggat
    29281 gttctttagc ttggtcaacc atggcttgca gggatttttc gcaggattta aaggaaaaag
    29341 tcagtggtta ggccttattt tagcaactat tgccatggta ggaggctacg ccttgggttc
    29401 tactttgatg aatggctggg cagcagccct cccagaaatt ctaccaaatt tcatgcaaaa
    29461 tatggtaggg atgattgtag gatttattct tagtcaaagt atcaagaaga ttaagtaata
    29521 ctcttcgaaa atctcttcaa accacgtcag cttccatctg caacctcaaa acactgtttt
    29581 gagcagcctg aggctagctt tctagtttgc actttgattt tcattgagta taaagaggtt
    29641 gagtaaaaag tatttcaaat aagaaaaacg catagtatca ggtgttgaat gaactgcccc
    29701 ccaaaaagtt agacagaaaa aatctaactt tttggggtgt ttttattatg aaattaa
//
LOCUS       DAVBDR010000023        28559 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.023, whole genome shotgun sequence.
ACCESSION   DAVBDR010000023 DAVBDR010000000
VERSION     DAVBDR010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 28559)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28559)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28559
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.023"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            complement(424..2151)
                     /gene="ezrA"
                     /locus_tag="VQ540_001031"
     CDS             complement(424..2151)
                     /gene="ezrA"
                     /locus_tag="VQ540_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HET2544846.1"
                     /translation="MSNGQLIYLMVAIAVILVLAYVVAIFLRKRNEGRLEALEERKEE
                     LYNLPVNDEVEAVKNMHLIGQSQVAFREWNQKWVDLSLNSFADIENNLFEAEGYNHSF
                     RFLKASHQIDQIESQITLIEEDIAAIRNALADLEKQESKNSGRVLHALDLFEELQHRV
                     AENSEQYGQALDEIEKQLENIQSEFSQFVTLNSSGDPVEAAVILDNTENHILALSHIV
                     DRVPALVTTLSTELPDQLQDLEAGYRKLIDANYHFVETDIEARFHLLYEAFKKNQENI
                     RQLELDNAEYENGQAQEEINALYDIFTREIAAQKVVENLLATLPTYLQHMKENNTLLG
                     EDIARLNKTYLLPETAASHVRRIQTELESFEAAIVEVTSNQEEPTQAYSVLEENLEDL
                     QTQLKDIEDEQISVSERLTQIEKDDINARQKANVYVNRLHTIKRYMEKRNLPGIPQTF
                     LKLFFTASNNTEDLMVELEQKMINIESVTRVLEIATNDMEALETETYNIVQYATLTEQ
                     LLQYSNRYRSFDERIQEAFNEALDIFEKEFDYHASFDKISQALEVAEPGVTNRFVTSY
                     EKTRETIRF"
     gene            complement(2233..4179)
                     /gene="gyrB"
                     /locus_tag="VQ540_001032"
     CDS             complement(2233..4179)
                     /gene="gyrB"
                     /locus_tag="VQ540_001032"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002283665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HET2544847.1"
                     /translation="MTEEIKNLQAQDYDASQIQVLEGLEAVRMRPGMYIGSTSKEGLH
                     HLVWEIVDNSIDEALAGFASHIQVFIEPDDSITVVDDGRGIPVDIQEKTGRPAVETVF
                     TVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVHVHKNGKIHYQEYRRGHVVAD
                     LEVVGDTDRTGTTVHFIPDPKIFTETTTFDFDKLNKRIQELAFLNRGLQISITDKRQG
                     LEQTKHYHYEGGIASYVEYINENKDVIFDTPIYTDGEMDDITVEVAMQYTTGYHENVM
                     SFANNIHTHEGGTHEQGFRTALTRVINDYARKNKLLKDNEDNLTGEDVREGLTAVISV
                     KHPNPQFEGQTKTKLGNSEVVKITNRLFSEAFSDFLMENPQIAKRIVEKGILAAKARV
                     AAKRAREVTRKKSGLEISNLPGKLADCSSNNPAETELFIVEGDSAGGSAKSGRNREFQ
                     AILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGAEFDVSKARYQKLVLMTDAD
                     VDGAHIRTLLLTLIYRYMKPILEAGYVYIAQPPIYGVKVGSEIKEYIQPGADQEIKLQ
                     EALARYSEGRTKPTIQRYKGLGEMDDHQLWETTMDPEHRLMARVSVDDAAEADKIFDM
                     LMGDRVEPRREFIEENAVYSTLDV"
     gene            complement(4194..4757)
                     /locus_tag="VQ540_001033"
     CDS             complement(4194..4757)
                     /locus_tag="VQ540_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HET2544848.1"
                     /translation="MKYHDYIWDLGGTLLDNYETSTAAFVETLALYGITQDHDSVYQA
                     LKVSTPFAIETFAPNLENFLEKYKENEARELEHPILFEGVSDLLEDILNQGGRHFLVS
                     HRNDQVLEILEKTSIAAYFTEVVTSSSGFKRKPNPESMLYLREKYQISSGLVIGDRPI
                     DIEAGQAAGLDTHLFTSIVNLRQVLDI"
     gene            complement(4842..5396)
                     /locus_tag="VQ540_001034"
     CDS             complement(4842..5396)
                     /locus_tag="VQ540_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DJ-1/PfpI family protein"
                     /protein_id="HET2544849.1"
                     /translation="MVKVAVMLAQGFEEIEALTVVDVLRRANITCDMVGFEEQVTGSH
                     AIQVRADHVFDGDLSDYDMIVLPGGMPGSAHLRDNQTLIQELQSFEQEGKKLAAICAA
                     PIALNQAEILKNKRYTCYDGVQEQILDGHYVKETVVVDGQLTTSRGPSTALAFAYELV
                     EQLGGDAESLRTGMLYRDVFGKNQ"
     gene            complement(5407..6630)
                     /locus_tag="VQ540_001035"
     CDS             complement(5407..6630)
                     /locus_tag="VQ540_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HET2544850.1"
                     /translation="MKRSLDSRVDYSLLLPVFFLLVIGVVAIYIAVSHDYPNNILPIL
                     GQQVAWIALGLVIGFVVMLFNTEFLWKVTPFLYILGLGLMILPIVFYNPSLVASTGAK
                     NWVSINGITLFQPSEFMKISYILMLARVIVQFTKKHKEWRRTVSLDFLLIFWMILFTI
                     PVLVLLALQSDLGTALVFVAIFSGIVLLSGVSWKIIIPVFVTAVTGVAGFLAIFISKD
                     GRAFLHQIGMPTYQINRILAWLNPFEFAQTTTYQQAQGQIAIGSGGLFGQGFNASNLL
                     IPVRESDMIFTVIAEDFGFIGSVLVIALYLMLIYRMLKITLKSNNQFYTYISTGLIMM
                     LLFHIFENIGAVTGLLPLTGIPLPFISQGGSAIISNLIGVGLLLSMSYQTNLAEEKSG
                     KVPFKRKKVVLKQIK"
     gene            complement(6667..9117)
                     /locus_tag="VQ540_001036"
     CDS             complement(6667..9117)
                     /locus_tag="VQ540_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DnaQ family
                     exonuclease/ATP-dependent helicase"
                     /protein_id="HET2544851.1"
                     /translation="MKTIGNRYVVVDLEATSTGSKAKIIQVGIVVIEDGEIVDHYTTD
                     VNPHEPLDAHIKELTGLTDQRLAQAPDFSQVARKIFDLVEDGIFVAHNVQFDANLLAE
                     NLFFEGYELRNPRVDTVELAQVFFPELEKYSLPILCRELGIPLKHAHTALSDAQATAE
                     LLLFLREKMTQLPKGLLERLLEMADALLYESYLVIEETYRNQSILSSPDLVQVQGLYF
                     KKTAASLEPRKLSQDFSKNISLLNLEVREEQESFAKEVGLLLKDEPVSLIQAPTGIGK
                     TYGYLLPALSQSKERQIVLSVPTKILQNQIMEEEGKRLKEVFHTDIHSLKGPQNYLKL
                     DAFYHSLQENDENRLFRRFKMQVLVWLTETETGDLDEIGQLYRYQHFLADLRHDGNLS
                     SQSLFVTEDFWKRSQERAETCKLLVTNHAYLVTRLEDNPEFVSDRLLIIDEVQKILLA
                     LENLLQETYDIQSIIDLIDKALVGEENRVQQRILESIRFECLYLIEQFQSGKSRKNIL
                     DSLDNLHQYFSELEVEGFDELVRYFTAEGDYWLEVTETSQKKIQISSTKSGRTLLSSL
                     LPESCQAMGVSATLEISQRVSLADLLGYPEAKFVKIESRGKQEQEVVMVKDFPLVTET
                     SLEVYAREVAALLVEIQAFQQPILVLFTAKDMLLAVSDLLTVSHLAQYKNGDVHQLKK
                     RFEKGEQQILLGAASFWEGVDFSSHPFVIQVVPRLPFQNPQEPLTKKINQELNQEGKN
                     AFYDYQLPMAIIRLKQALGRSMRREYQRSLTLILDRRIIGKRYGKQIVASLAEEATVK
                     TISRSEVDEAIDRFFNEL"
     gene            complement(9316..10245)
                     /locus_tag="VQ540_001037"
     CDS             complement(9316..10245)
                     /locus_tag="VQ540_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006154193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HET2544852.1"
                     /translation="MEKIVITATAESIEQVEQLLEAGVDRIYVGEKDFGLRLPTTFSY
                     DQLREIAKLVHDAGKELLVAVNALMHQDMMDRIKPFLDFLEEIKTDYITIGDAGVFYV
                     VNRDGYSFKTIYDASTMVTSSRQINFWGQKAGASEAVLAREIPSAELFKMPEILEIPA
                     EVLVYGASVIHHSKRPLLQNYYNFTHIDDEKTHKRDLFLAEPSDPESHYSIFEDNHGT
                     HIFANNDLDLMIKLTELVEHGFTRWKLEGLYTPGQNFVEIAKLFIQARSLIQEGNFSH
                     DQAFLLDEEVRKLHPKNRFLDTGFYDYDPDMVK"
     gene            10385..10672
                     /locus_tag="VQ540_001038"
     CDS             10385..10672
                     /locus_tag="VQ540_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3270 domain-containing protein"
                     /protein_id="HET2544853.1"
                     /translation="MPVRKLQSYEVDYQEELNQQLPHYQAYTPEAQSDANLKEILFFI
                     NIAVFCICIAIFSFIFLALKLSTALAFAAAIGFSLLVLKVQRSIIKRKRRR"
     gene            complement(10706..12040)
                     /gene="ciaH"
                     /locus_tag="VQ540_001039"
     CDS             complement(10706..12040)
                     /gene="ciaH"
                     /locus_tag="VQ540_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000491790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     CiaH"
                     /protein_id="HET2544854.1"
                     /translation="MFSKLKKTWYADDFSYFIRNFGVFTLIFSTMTLIILQVMHSSLY
                     TSVDDKLHGLSENPQAVIQLAINRATEEIKDLENARADASKVEIKPNVSSNTEVILFD
                     KDFTQLLSGNRFLGLDKIKLEKKELGHIYQIQVFNSYGQEEIYRVILMETNISSVSTN
                     IKYAAVLINTSQLEQASQKHEQLIVVVMASFWILSLLASLYLARVSVRPLLESMQKQQ
                     SFVENASHELRTPLAVLQNRLETLFRKPEATIMDVSESIASSLEEVRNMRFLTTSLLN
                     LARRDDGIKPELAEVPTSFFNTTFTNYEMIASENNRVFRFENRIHRTIVTDQLLLKQL
                     MTILFDNAVKYTEEDGEIDFLISATDRNLYLLVSDNGIGISTEDKKKIFDRFYRVDKA
                     RTRQKGGFGLGLSLAKQIVDALKGTVTVKDNKPKGTIFEVKIAIQTPSKKKK"
     gene            complement(12030..12704)
                     /gene="ciaR"
                     /locus_tag="VQ540_001040"
     CDS             complement(12030..12704)
                     /gene="ciaR"
                     /locus_tag="VQ540_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CiaR"
                     /protein_id="HET2544855.1"
                     /translation="MIKILLVEDDLGLSNSVFDFLDDFADVMQVFDGEEGLYEAESGV
                     YDLILLDLMLPEKNGFQVLKELREKGITTPVLIMTAKESLDDKGHGFELGADDYLTKP
                     FYLEELKMRIQALLKRSGKFNENTLTYGNIVVNLSTNTVKVEDTPVELLGKEFDLLVY
                     FLQNQNVILPKTQIFDRLWGFDSDTTISVVEVYVSKVRKKLKGTTFAENLQTLRSVGY
                     LLKDVQ"
     gene            complement(12813..15359)
                     /locus_tag="VQ540_001041"
     CDS             complement(12813..15359)
                     /locus_tag="VQ540_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001149089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M1 family metallopeptidase"
                     /protein_id="HET2544856.1"
                     /translation="MQAVEHFIKQFVPEHYDLFLDLSRETKTFSGKVTITGQAQSDRI
                     SLHQKDLEITSVEVAGQARPFTVDHDNEALHIELAEAGQVELVLAFSGKITDNMTGIY
                     PSYYTVDGVKKEVLSTQFESHFAREAFPCVDEPEAKATFDLSLRFDQAEGELALSNMP
                     EIDVENRKETGIWKFETTPRMSSYLLAFVAGDLQGVTAKTKNGTLVGVYSTKAHPLSN
                     LDFSLDIAVRSIEFYEDYYGVKYPIPQSLHIALPDFSAGAMENWGLVTYREVYLVVDE
                     NSTFASRQQVALVVAHELAHQWFGNLVTMKWWDDLWLNESFANMMEYVCVDTIEPSWN
                     IFEDFQTGGVPLALERDATDGVQSVHVEVKHPDEINTLFDGAIVYAKGSRLMHMLRRW
                     LGDADFAKGLHAYFEKHQYSNTIGSDLWDALGQASGRDVAAFMDSWLEQPGYPVLTVK
                     VENDVLKISQKQFFIGENEDKNRLWVVPLNSNWKGLPDTLETESIEIPGYAALLAENE
                     GALRLNTENTAHYITDYQGDLLEAVLAELETLDNTSKLQIVQERRLLAEAGHIAYADL
                     LPVLDKLAKEESYLVVSAVSQVISALERFIDEGTDAETAFKGLVAKLARHNYDRLGFE
                     AKDGESDEDELVRQLAVSMMIRSNDAEASQVASQIFATHKENLAGLPAAIRSQVLINE
                     MKHHETKDLLALYLDTYTHATDAVFKRQLAAALAYSTDADNIQNLITSWKDKFVVKPQ
                     DLSAWYYQFLAHQATQKTAWSWARENWAWIKAALGGDMSFDSFVILPAHVFKTQQRLA
                     EYKEFFEPQLSDLALSRNIGMGIKEIAARVDLISREKAAVEAVVLQYGNA"
     gene            complement(15483..15923)
                     /locus_tag="VQ540_001042"
     CDS             complement(15483..15923)
                     /locus_tag="VQ540_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HET2544857.1"
                     /translation="MIPQEMWNKYKQINPLIGDEIDAWAFGVEPDLLADLVFKGEKTA
                     TASAYDLYVLEDEPLPQVGTFDVILDSQNQSVCIVEITKVSVELFNQVSAQHAFKEGE
                     GDKSLAYWRQVHEDFFTDCLGEVGLTFTPESKVVLEEFRKVYPL"
     gene            complement(15898..16767)
                     /locus_tag="VQ540_001043"
     CDS             complement(15898..16767)
                     /locus_tag="VQ540_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PEP-utilizing enzyme, TIM barrel domain protein"
                     /protein_id="HET2544858.1"
                     /translation="MRNQLALSGEKILEKIYPQLFHHVGMIRGEYLLRELNQNIILAS
                     CQQFVKDYLETICSLYSDEEVWYRFTELTNTEANCLVGTKEFFDEGHPLFGYRGTRRL
                     LACLDEFQAEAHVVTEVYQTNPNLSVIFPFVNDADQLKQAITVLRQYGFTGKVGTMIE
                     LPSAYFDLSSILETGISKIVVGMNDLTSFVFATMRNSQWHDLESPIMLDMLRDMQDKA
                     RKNKINFAVAGYLNTSFIQKMNQLGIKCIIHYSSIPEIFDLEIDHPDHLKHIKEESKK
                     LQRSTHDTARNVE"
     gene            complement(16809..17537)
                     /locus_tag="VQ540_001044"
     CDS             complement(16809..17537)
                     /locus_tag="VQ540_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2544859.1"
                     /translation="MELFKTWKKNMVLYGLKSQIGTVYRNNDRTTSFYDVGNFLYLAG
                     ELDSRFWEDFVRKYGLDYKIIISENTNWQDFLHRKVGLNSFTRYSFKDKANFQVEFLN
                     NLVTHLEEGYNIVPIDNHIYNCFSTEEWSQDLQGDFESYQDFVLKGGFGFVILKNNEL
                     IAGISSGLVYRKAVEVEVATRPNEQGNGFAKKLGAAMILESLNRDMFPLWDAHNEASK
                     KVAEFLGYELSEPYEAFELEEILI"
     gene            complement(17545..18024)
                     /locus_tag="VQ540_001045"
     CDS             complement(17545..18024)
                     /locus_tag="VQ540_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HET2544860.1"
                     /translation="MEIKKHFGVYAVCLENGKLLCIEKTRGPYQHRYDLPGGSQQLGE
                     GLTETLTREVMEETGFTVRSYSNPRIYDVFVREELTNFMVDHVMALYDVEMNESAPQV
                     TTSEAVSDGANDSLGYIWMDIQEITEENASPLVLKVKSELLGFPELDKTSYMNWKVK"
     gene            complement(18035..18733)
                     /locus_tag="VQ540_001046"
     CDS             complement(18035..18733)
                     /locus_tag="VQ540_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HET2544861.1"
                     /translation="MTKRVLITGVSSGIGLAQARLFLEKGYQVYGVDQGEKPLLEGDF
                     HFLQRDLTLDLEPIFDWCPQVDVLCNTAGVLDDYKPLLEQTAQDIQEIFEINYIIPVE
                     LTRYYLTQMLENKKGIIINMCSIASSLAGGGGHAYTSSKHALAGFTKQLALDYAEAGI
                     QVFGIAPGAVKTAMTAADFEPGGLADWVASETPIKRWIEPEEIAELSLFLASGKASAM
                     QGQILTIDGGWSLK"
     gene            complement(18726..18992)
                     /locus_tag="VQ540_001047"
     CDS             complement(18726..18992)
                     /locus_tag="VQ540_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HET2544862.1"
                     /translation="MKNVELKEKNMTFEEILPGLKAKRKYVRTGWGGAENYVQLFDTI
                     EQNGLALEMTPYFLINVSGEGEGFSMWSPTVCDVLATDWVEVHD"
     gene            complement(19058..19984)
                     /locus_tag="VQ540_001048"
     CDS             complement(19058..19984)
                     /locus_tag="VQ540_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase family oxidoreductase"
                     /protein_id="HET2544863.1"
                     /translation="MRYITLGQDDKELSEIVLGMMRIKDKSVKEVEELVETALSVGIN
                     AFDLADIYGRGRCEELLGLVLKNRPDLREKMWIQSKCGIRIEEFTYFDFSKDYIIKSV
                     DGILQRLKIDHLDSLLLHRPDALMESDQVAEAFNLLYKQGKVRDFGVSNQNPMMMELL
                     KKDVKQPLAVNQLQLSAAFTPGFESAFHVNMEDSQAAMRDGSIFEYCQLHDVVIQAWS
                     VLQFGYFKGNFVGNEKFQALNQVLDRLAIKYGVTSSTIAISWILRYPAKMQAVVGTTN
                     PKHLREVSRAANFSLTRKEWYEIYLAAGNNLP"
     gene            complement(20059..20874)
                     /locus_tag="VQ540_001049"
     CDS             complement(20059..20874)
                     /locus_tag="VQ540_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2544864.1"
                     /translation="MKKMKYYEETSALLHEFSEENQKYFEELWESFNLAGFLYDEDYL
                     REQIYLMMLDFSEAERDGMSAEDYLGKNPKKIMKEILKGAPRSSIKESLLTPILVLAV
                     LRYYQLLSDFSKGPLLTVNLLTFLGQLLIFLIGFGLVATILRRSLVQDSPKMKIGTYI
                     VVGTIVLLVVLGYVGMASFIQEGAFYIPAPWDSLSVFTISLVIGIWNWKEAVFRPFVS
                     MIIAHLVVGSLLRYYEWMGISNVFLTKVIPLAVLFIGIFVLFRGFKKIKWSEV"
     gene            complement(20878..21198)
                     /locus_tag="VQ540_001050"
     CDS             complement(20878..21198)
                     /locus_tag="VQ540_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HET2544865.1"
                     /translation="MKETQLLKGVLEGCVLDMIGQKERYGYELVQTLREAGFDTIVPG
                     TIYPLLQKLEKNQWIRGDMRPSPDGPDRKYFSLTKEGEERVSVFWQQWDDLSQKVEGI
                     KNGG"
     gene            complement(21495..21575)
                     /locus_tag="VQ540_001051"
                     /pseudo
     CDS             complement(21495..21575)
                     /locus_tag="VQ540_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(21619..23616)
                     /gene="metG"
                     /locus_tag="VQ540_001052"
     CDS             complement(21619..23616)
                     /gene="metG"
                     /locus_tag="VQ540_001052"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HET2544866.1"
                     /translation="MSEKNFYITTPIYYPSGKLHIGSAYTTIACDVLARYKRLMGYDV
                     FYLTGLDEHGQKIQQKAEEAGITPQAYVDGMAVGVKELWQLLDISYDKFIRTTDDYHE
                     KVVAQVFERLLAQDDIYLGEYSGWYSVSDEEFFTESQLAEVFRDEAGNVTGGIAPSGH
                     EVEWVSEESYFLRLSKYQDRLVEFFKAHPEFITPDGRLNEMLRNFIEPGLEDLAVSRT
                     TFTWGVPVPSNPKHVVYVWIDALLNYATALGYAQDEHGNFDKFWNGTVFHMVGKDILR
                     FHSIYWPILLMMLDVKLPDRLIAHGWFVMKDGKMSKSKGNVVYPEMLVERYGLDPLRY
                     YLMRNLPVGSDGTFTPEDYVGRINYELANDLGNLLNRTVSMINKYFDGQIPAYVEGVT
                     EFDHVLAEVAEQSIADFHTHMEAVDYPRALEAVWTLISRTNKYIDETAPWVLAKDEAL
                     RDQLASVMSHLAASIRVVAHLIEPFMMETSRAVLTQLGLEEVSSLENLSLADFPADVT
                     VVAKGTPIFPRLNMEEEIAYIKEQMEGNKPAVEKEWNPDEVELKLNKDEIKFEDFDKV
                     EIRVAEVKEVSKVEGSDKLLQFRLDAGDGEDRQILSGIAKYYPNEQELVGKKVQIVAN
                     LKPRKMMKKYVSQGMILSAEYDGKLTLLTVDPAVPNGSVIG"
     gene            complement(23740..24999)
                     /locus_tag="VQ540_001053"
     CDS             complement(23740..24999)
                     /locus_tag="VQ540_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2544867.1"
                     /translation="MQNLKFAFSSIMAHKMRSLLTMIGIIIGVSSVVVIMALGDSLSR
                     QVNKDMTKSQKNISVFFSPKKSKDGSFTQKQSAFTVSGKEEEVPVEPPKPQESWVQEA
                     AKLKGVDSYYVTNSTNAILTYQDKKVENANLTGGNRTYMDAVKNEIIAGRSLREQDFK
                     EFASVILLDEELSISLFESPQEAINKVVEVNGFSYRVIGVYTSPEAKKSKIYGFGGLP
                     ITTNISLAANFNIDEIASIVFRVNDTSLTPTLGPELARKMTELAGLQQGEYQVADESV
                     VFAEIQQSFSFMTTIISSIAGISLFVGGTGVMNIMLVSVTERTREIGLRKALGATRAN
                     ILIQFLIESMILTLLGGLIGLTIASGLTALAGLLLQGLIEGIEVGVSIPVALFSLAVS
                     ASVGMIFGVLPANKASKLDPIEALRYE"
     gene            complement(25001..25702)
                     /locus_tag="VQ540_001054"
     CDS             complement(25001..25702)
                     /locus_tag="VQ540_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2544868.1"
                     /translation="MKQLISLKNIFRSYRNGDQELQVLKNINLEVNEGEFVAIMGPSG
                     SGKSTLMNTIGMLDTPTSGEYYLEGQEVAGLGEKQLAKVRNQQIGFVFQQFFLLSKLN
                     ALQNVELPLIYAGVSSSKRRKLAEEYLDKVELTERSHHLPSELSGGQKQRVAIARALV
                     NNPSIILADEPTGALDTKTGNQIMQLLVDLNKEGKTIIMVTHEPEIAAYAKRQIVIRD
                     GVISSDSAQLGKEEN"
     gene            complement(25686..26885)
                     /locus_tag="VQ540_001055"
     CDS             complement(25686..26885)
                     /locus_tag="VQ540_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HET2544869.1"
                     /translation="MKKKNGKAKKWQLYAAIGAASVVVLGAGGILLFRQPSQTAVKDE
                     PTHLVVAKEGSVASSVLLSGTVTAKNEQYVYFDASKGDLDEILVSVGDKVSEGQALVK
                     YSSSEAQAAYDSASRAVAKADRHINELNQARNEAASAQAPQLPAPVGGEDATVQSPTP
                     VAGNSVASIDAQLGDARDARADAAAQLSKAQSQLDATTVLSTLEGTVVEVNSNVSKSP
                     TGASQVMVHIVSNENLQVKGELSEYNLANLSVGQEVSFTSKVYPDKKWTGKLSYISDY
                     PKNNGEAASPAAGNNTGSKYPYTIDVTGEVGDLKQGFSVNIEVKSKTKAILIPVSSLV
                     MDDSKNYVWIVDEQQKAKKVEVSLGNADAENQEITSGLTNGAKVISNPTSSLEEGKEV
                     KADEATN"
     gene            27171..28517
                     /gene="gor"
                     /locus_tag="VQ540_001056"
     CDS             27171..28517
                     /gene="gor"
                     /locus_tag="VQ540_001056"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HET2544870.1"
                     /translation="MREYDIIAIGGGSGGIATMNRAGEHGAKAAVIEEKKLGGTCVNV
                     GCVPKKIMWYGAQIAETFHQFGEDYGFKTTDLNFDFATLRRNREAYIDRARSSYDGSF
                     KRNGVDLIEGHAEFVDSHTVSVNGELIRAKHIVIATGAHPSIPNIPGAELGGSSDDVF
                     AWEELPESIAILGAGYIAVELAGVLHTFGVKTDLFVRRDRPLRGFDSYIVEGLVKEME
                     RTNLPLHTHKVPVKLEKTTDGITIHFEDGTSHTASQVIWATGRRPNVKGLQLEKAGVT
                     LNERGFIQVDEYQNTVVEGIYALGDVTGEKELTPVAIKAGRTLSERLFNGKTTAKMDY
                     STIPTVVFSHPAIGTVGLTEEQAIKEYGQDQIKVYKSSFASMYSACTRNRQESRFKLI
                     TAGSEEKVVGLHGIGYGVDEMIQGFAVAIKMGATKADFDATVAIHPTASEEFVTMR"
BASE COUNT         8539 a         6285 c         5101 g         8634 t
ORIGIN      
        1 tagaggccta tttaccgtgg actaaagttg tacaagaaaa gtgcaaataa gaaatctcca
       61 gattaggaac tatccgtgag ttctctagtc tggagatttt tcaatagact tcgttattgg
      121 acggttacca agttacttca aagtacagat ttgaagctgc agataagact gacgaaatca
      181 ctttaatact aaatgaaaat caaaaagcaa actaagaagc tagcctcagg ctgtacttga
      241 gtacggtaag gcgacgctga cgtgatttga agagattttc gaagagtata aaacactgtt
      301 ttgaagtggt ggataaatcg gctgggtaaa aactcaatct caggagaaaa tgaagtaaat
      361 ctccccacaa ctatagaaaa agatttgatt ctgctcctca cacaataaaa tctttttctt
      421 ttattaaaaa cgaatcgttt cacgtgtttt ctcatatgag gtaacaaagc gattggttac
      481 accaggctct gccacttcca atgcttgaga aatcttgtca aatgaagcgt gataatcaaa
      541 ttctttttca aaaatatcta aagcttcgtt aaatgcttct tgaatgcgtt catcaaatga
      601 gcgatagcgg ttagaatatt gcaagagttg ctctgtcaaa gttgcatatt gtacaatatt
      661 ataagtttcc gtttctaaag cttccatatc attcgttgca atttcaagaa ctcgggtaac
      721 agattcaatg ttaatcattt tttgttctaa ctcaaccatt aaatcctcgg tattattgct
      781 tgccgtaaag aataacttca agaaagtttg tggaatacct ggcagattgc gtttttccat
      841 gtatcgcttg atagtatgga gacgattgac ataaacattg gccttttgac gtgcattaat
      901 atcatctttc tcaatttgtg tcaggcgctc actaactgaa atttgctcat cttcaatatc
      961 ttttagttga gtttgtaaat cctcaagatt ttcttcaaga actgaataag cttgggttgg
     1021 ttcttcttga tttgaagtta cctcaacaat agctgcctca aaactctcta attctgtctg
     1081 aatacgacga acatggcttg cagctgtctc aggaagtaaa taggtcttgt tcaaacgtgc
     1141 aatatcttct cccaataaag tattattctc tttcatatgt tgaaggtaag ttggaagagt
     1201 tgcaagtaga ttttccacta ctttctgagc agcaatttct cgagtaaaaa tatcatacaa
     1261 ggcattgatt tcctcttgtg cctgtccatt ctcatattcg gcattatcca attccaactg
     1321 acgaatattc tcttggtttt tcttgaatgc ttcataaagc aagtggaaac gcgcttcaat
     1381 atccgtttca acaaaatgat aattagcatc aattagttta cgataaccgg cttccaaatc
     1441 ctgtaattga tctggcaatt ctgtagaaag cgtcgtaacc aaggctggaa cacgatccac
     1501 aatatgactt aaggccaaaa tgtgattttc tgtattatcc aaaatcactg cggcttccac
     1561 agggtcaccc gatgaattca aggttacaaa ttgtgaaaat tcagattgga tattttctaa
     1621 ttgtttttca atttcatcca aggcttgacc atactgttct gaattttcag caactctatg
     1681 ctgaagttcc tcaaataaat ccaaagcatg aagaacacga ccactatttt tagattcttg
     1741 cttctctaag tctgccaaag cattgcgaat tgccgcaata tcttcttcaa tcaaagtaat
     1801 ttgactctca atttggtcaa tttgatgact ggccttgaga aaacgaaatg aatggttata
     1861 accttctgct tcaaagagat tattttcaat atcggcaaaa gagttgagag ataaatcgac
     1921 ccatttttga ttccattcac ggaaagccac ttgactttgt ccaatcaagt gcatattttt
     1981 tacagcttct acttcatcat ttactggaag attgtatagt tcttcttttc tttcttctag
     2041 cgcctctaat ctcccctcgt ttcgcttacg tagaaagatt gccactacat aagccagaac
     2101 taaaatgact gcaattgcaa ccattaaata aattagttgt ccattagaca tatcaaactc
     2161 cttttttact tgaaacaatc gtaacgatta tatcatattt tttagaccaa gggaactact
     2221 tctccctatt ttttagacat caagtgtact atagacagca ttttcttcga taaactcacg
     2281 acgaggctct actcgatccc ccatcaacat atcaaagatt ttatctgctt ctgcagcatc
     2341 atctacagaa actctagcca tcaagcgatg ttcgggatcc atggttgttt cccacagctg
     2401 atgatcgtcc atttcaccta gccccttata acgctgaata gtcggtttgg tacgaccttc
     2461 actataacgg gctaaagctt cttggagttt gatttcttga tctgcacccg gctggatata
     2521 ttctttaatc tcgcttccaa ccttgacacc atagattggt ggttgggcaa tataaacata
     2581 accagcttct aggattggtt tcatataacg ataaatcaag gttaaaagaa gggtacgaat
     2641 atgggctcca tcgacatcgg catcggtcat caaaacgagt ttttggtaac gggctttcga
     2701 aacatcaaat tctgcgccaa atcctgttcc catggctgtg aaaagactac gaatttcttc
     2761 gttagctaga atcttatcca tacttgcttt ttcaacgttc aaaatcttac cgcgaattgg
     2821 aaggatagcc tgaaactcac ggttacgacc agatttggct gatccaccag ctgagtctcc
     2881 ttcgacgatg aagagttctg tttcagcagg gttattagaa gaacagtctg ctagtttccc
     2941 tggaaggttg gaaatttcca aaccagattt tttacgtgtg acttcacgcg cacgcttggc
     3001 agccacacga gccttggcag ctaaaatccc tttttccacg atacgtttgg caatctgtgg
     3061 attttccatg aggaaatcgg agaaggcttc actgaagagg cgattggtaa tcttgaccac
     3121 ttcgctattt cccaatttgg tcttggtttg tccttcaaac tgtggatttg ggtgtttaac
     3181 tgagataact gcagttaatc cttcgcgaac atcttcccct gttaaattat cttcattgtc
     3241 tttcagtaac ttattcttac gagcataatc attgataaca cgagtcagtg ccgtacggaa
     3301 accttgttca tgcgttccac cttcatgggt atgaatatta ttggcgaaac tcatgacatt
     3361 ttcatggtaa cctgttgtgt actgcatggc tacctcaact gtgatatcat ccatctcacc
     3421 gtctgtatag attggtgtat caaagattac atccttgttc tcgttgatat attcaacgta
     3481 actagcaatc ccaccttcat aatgataatg cttggtttgt tccaaacctt ggcgcttatc
     3541 agtgatagaa atttgaagac cgcgatttag aaaggccaac tcttgaatcc gtttatttaa
     3601 tttatcaaaa tcaaaggttg ttgtttcagt aaagattttt gggtccggta tgaagtgaac
     3661 cgttgttcca gttctatctg tatccccaac cacctcaagg tctgcaacaa catgaccacg
     3721 acggtattct tggtaatgaa tcttaccgtt tttatggaca tgaacgtcta attgagtgga
     3781 aagggcatta actactgacg accccacccc gtgaagacca cctgaaacct tgtatccacc
     3841 accgccgaac tttcctccag catgaaggac tgtaaagacg gtctcaacag caggacggcc
     3901 tgttttttcc tgaatatcga ctgggatacc acgcccatca tccacaacag taatcgaatc
     3961 atctggctca ataaaaactt gaatatggct ggcaaatcct gccaaggcct cgtcaattga
     4021 gttatcaaca atttcccaga ctagatggtg aagaccttct tttgaggttg atccaatgta
     4081 catccctgga cgcatacgaa cagcctctaa gccctctaaa acttgaattt gactggcatc
     4141 ataatcctgt gcctgcagat ttttgatttc ttctgtcatc ttattccttt ttcttatatg
     4201 tctaatactt gtcttaaatt cacgatactg gtaaacaagt gggtatcaag tcctgcagct
     4261 tgacctgctt cgatatcaat cggccgatca ccaatgacaa gaccagagct aatctgatac
     4321 ttttctctta aataaagcat ggattcggga tttggctttc tcttaaagcc tgagctagaa
     4381 gtcaccactt ctgtaaaata agctgctata gaggtttttt ctaaaatttc caaaacctga
     4441 tcatttcgat gagagaccaa aaaatgacgg ccaccttgat ttaaaatgtc ttccaatagg
     4501 tcagaaactc cttcaaataa aatcgggtgt tcaagctctc tggcttcatt ttccttgtac
     4561 ttttctaaaa aattctctaa attgggagcg aatgtctcaa tcgcaaaagg agtagaaacc
     4621 tttaaagctt gatagacact gtcatggtct tgtgtgatac catacagtgc caatgtttca
     4681 acaaatgcag ctgttgaagt ttcataatta tccagtaaag ttccacctaa atcccagatg
     4741 taatcgtgat atttcatacc cttcattata gcattttttt atgaaaaaag cgatgatttc
     4801 cctgagtttt ccacataaaa aacgagagaa taactcccgt tttactgatt tttaccaaag
     4861 acatctcgat agagcattcc tgttcgtaaa ctctctgcgt cccctcctag ttgctccacc
     4921 aactcgtagg caaaggcaag ggctgttgaa ggaccccgac tggttgtcaa ctgaccatct
     4981 accactactg tttccttgac gtagtgacca tcaaggattt gctcttgaac gccgtcataa
     5041 caagtgtatc gcttattttt caatatctct gcttgattga gggcaattgg tgccgcacaa
     5101 atggctgcta gtttcttccc ttcttgctcg aagctttgca attcttgaat caaggtctga
     5161 ttatcacgta aatgtgcaga accaggcata cctccaggaa gaacaatcat atcatagtct
     5221 gataaatctc catcaaagac atgatctgct cttacttgga ttgcatgcga acccgttact
     5281 tgctcttcaa aaccaaccat atcacatgtg atattggctc gacgcaagac atctacaact
     5341 gtcaaggctt caatttcttc aaagccctga gctaacataa ctgctacttt taccatgatt
     5401 ttctccttat ttaatttgtt ttaatacaac ctttttccgt ttgaatggga cttttccgct
     5461 cttttcttca gctagattag tctggtaact catcgataaa agcaaaccaa caccaatcag
     5521 attactgata atagctgatc ccccttgcga aatgaaaggc aagggaatcc ccgtcaaagg
     5581 aagtagtcca gtcacagcac cgatattctc aaagatgtgg aagagcaaca tcataatcaa
     5641 acctgtggaa atataagtgt agaactggtt atttgattta agagtaatct tcaacatacg
     5701 gtaaatcaac atgagataga gggcaataac caggacagag ccaataaagc caaaatcttc
     5761 tgcaataacc gtaaaaatca tatctgactc tcgaactggg ataagcagat tcgaagcatt
     5821 aaatccctga ccaaataagc caccactccc aatggcaatc tgcccttgag cctgctggta
     5881 agtcgttgtt tgggcaaact caaagggatt gagccaagcc aaaatccgat tgatttggta
     5941 ggtcggcatt ccaatctggt gaagaaaagc tcgtccgtcc ttgctaataa agatagctaa
     6001 gaaaccagca actcctgtta cagcagtcac aaatactggg ataataattt tccaagaaac
     6061 ccctgataat aaaacgattc ctgagaaaat ggctacaaaa accaaagccg tccccaagtc
     6121 actttgaagt gctaaaagaa ctaggactgg aatggtaaag agaatcatcc agaaaattaa
     6181 caaaaagtcc agcgaaaccg tgcgtctcca ttccttatgt ttctttgtaa attggacaat
     6241 gacacgagcc aacatgagga tataggatat cttcataaat tctgacggtt gaaatagggt
     6301 aattccattt attgataccc agtttttggc acccgttgat gcaactaagc ttggattata
     6361 aaatacaatc ggcaagatca taagtcccaa gcctaaaata tatagaaagg gggtcacctt
     6421 ccaaagaaat tctgtattaa agagcatgac cacaaaacca atcacaagcc ccaaggcaat
     6481 ccaggcgacc tgctgcccta aaatgggcag aatattattg ggataatcat gactaacggc
     6541 tatatagata gccaccacac cgatgaccag tagaaaaaat actggcaaga gcaaactata
     6601 atcgactcta gagtcgagag aacgtttcat atatactaac cttatacttt catacaatac
     6661 tatttatcaa agttcattaa aaaatctatc aatagcctcg tcaacttcgg atcgagagat
     6721 ggttttaaca gtcgcttctt ctgctagaga tgctactatt tgtttgccgt atcgttttcc
     6781 gatgattctc ctatccaaaa taagagttaa ggaacgttgg tattcacgtc tcatacttct
     6841 tcccaaagcc tgttttaaac gaataatggc cattggcaat tgataatcat aaaaggcatt
     6901 tttcccttct tgattcagtt cttgattaat ctttttcgtc aagggttctt gaggattttg
     6961 gaaaggaagc ctcggtacaa cttgaatcac aaaaggatgg cttgaaaaat caactccctc
     7021 ccagaaactt gctgcaccaa gcaagatttg ttgttcacct ttttcaaagc gtttctttag
     7081 ctgatgaaca tccccatttt tatactgggc caagtggcta actgtaagta aatccgatac
     7141 tgctagaagc atgtctttag cggtaaagag aaccaaaatc ggttgctgga aagcttgaat
     7201 ttccactagt aaagcagcta cctctctggc atagacttct aaggaggttt ctgttaccag
     7261 agggaaatct ttgaccataa ccacttcttg ttcctgtttt ccccgagatt caatcttgac
     7321 aaatttggct tcaggatagc ctaaaaggtc tgccaaagaa accctctgac taatctcaag
     7381 agtagccgat actcccatgg cttggcaact ctcaggaagt aaagaggaca gaagagtacg
     7441 gcctgatttt gtagaagaaa tctgaatttt cttttgactc gtttcagtta cttcaagcca
     7501 gtaatcacct tcagctgtaa aatagcgaac cagctcatca aagccttcta cttctaattc
     7561 tgaaaaatac tgatggagat tgtccagaga atctaagata tttttcctag atttaccaga
     7621 ctgaaattgt tctatcaagt agagacactc aaagcgaata ctttctagta tccgttgttg
     7681 aaccctgttt tcttctccta ctaaagcctt atcaattaaa tcgataatag attgtatatc
     7741 gtaggtctct tgaagcagat tttctagagc taacaaaatc ttttggactt catcaataat
     7801 cagtaaacgg tcactgacaa attcaggatt atcttcaagt ctggtcacga gataggcatg
     7861 attagtcact aaaagcttgc aagtctctgc cctttcttga ctacgtttcc aaaaatcttc
     7921 cgtcacaaat aagctctggg atgataaatt cccatcatga cgaaggtctg ctagaaaatg
     7981 ttggtaacga tagagttgcc cgatttcatc caaatctcct gtctctgtct cagtaagcca
     8041 gaccaagact tgcattttaa agcgtctaaa taagcgattt tcatcatttt cctgcaagga
     8101 atgataaaag gcatccaact tcagataatt ttgtggtccc tttaagctat gaatatctgt
     8161 atggaacact tccttgaggc gtttaccttc ttcttccatg atttgatttt gaagaatctt
     8221 tgtcggaaca ctaagaacaa tttgtcgctc tttggattga gataaagcgg gtaagagata
     8281 gccataggtt ttcccaatcc ctgtcggcgc ttgaatcaga gagacaggtt catctttcaa
     8341 tagcaagcca acctctttag caaaactttc ttgttcctcc ctcacttcaa ggttcaacag
     8401 agaaatattt ttagaaaagt cttgagatag ttttcgtggc tccagagaag ctgccgtttt
     8461 cttaaaatac agaccttgaa cttggaccaa gtctggagaa ctcaggatag attggttgcg
     8521 ataagtttcc tcaataacca ggtaggactc atataggaga gcgtcagcca tttccagcaa
     8581 gcgttccaag agacctttag gaagctgagt catcttttcc cgtaaaaaaa gaagtaattc
     8641 tgctgtagct tgggcatctg aaagggctgt gtgtgcgtgt ttaagaggaa ttcctaattc
     8701 tcgacacaaa atcggcaagc tatatttttc cagttcaggg aaaaagacct gggccaattc
     8761 gaccgtatca acacgagggt ttcttagctc atagccttca aaaaataaat tttccgccaa
     8821 gagattagca tcaaactgaa cattatgggc tacaaaaatc ccatcctcca ccaagtcaaa
     8881 tatttttctg gcaacttgcg aaaaatcagg tgcttgcgcc agacgttggt ctgtcaatcc
     8941 tgtcagttct ttgatatgag catccaaggg ttcatgtgga ttgacatccg tcgtatagtg
     9001 atcgacgatt tctccgtcct caatcacgac aattcccact tggataattt tagccttact
     9061 acctgtgcta gttgcctcta aatccaccac aacatagcga ttaccaatcg ttttcattat
     9121 aaaaaattat accaaaaaaa gggccatttg gcacctgcaa acataggata attttcaaac
     9181 tcaagaacac tacttttctt aaaaatccca tcgaatagag cattctagcc tgctgatttt
     9241 ttaaaatagt gaagaaatac gaaaaattga gagaagaaat gttttcatct tccttctctc
     9301 aacgaatcat gtattttatt taaccatgtc aggatcgtag tcataaaatc ctgtatcaag
     9361 gaaacggttt ttagggtgaa gtttacgaac ttcttcatcc agcaagaagg cttggtcatg
     9421 gctaaagttg ccctcttgaa tcaagctacg cgcttggata aagagttttg caatctcaac
     9481 aaagttctga ccaggagtgt agagcccttc tagtttccag cgagtaaagc catgctccac
     9541 caattctgtt aatttgatca tcaaatcaag gtcattgttg gcaaagatat gggtcccatg
     9601 attatcttca aaaatggaat agtggctctc tggatcactt ggctcagcca agaagaggtc
     9661 acgtttatgc gtcttttcat catcgatatg tgtaaagtta tagtagtttt gcaagagtgg
     9721 acgtttagaa tgatggatga cgctagcacc gtaaaccaaa acttcagcag gaatttccaa
     9781 aatctctggc attttgaaaa gttcagctga tggaatttca cgcgccaaaa cagcctcaga
     9841 tgcgccagcc ttttgtcccc agaagttaat ctgacgactg ctagttacca tggttgaagc
     9901 atcgtagatg gtcttaaatg aataaccatc gcggttaact acgtaaaaga cgcctgcatc
     9961 cccaatcgta atatagtctg tcttgatttc ttccaagaag tctaagaaag gcttgatacg
    10021 gtccatcata tcttggtgca tgagagcatt gaccgcaacg agcaattcct taccagcatc
    10081 atgaaccaac ttagcgattt cacgtaattg gtcataacta aaggtcgttg gcagacgaag
    10141 gccaaaatct ttctcaccga catagatacg gtctacgcca gcttcgagta gttgttcaac
    10201 ttgttcaata ctttcagcag ttgctgtaat gacaatcttt tccataagaa aaattatacc
    10261 acatttctcc aaaatcatcc atgctttgaa aatgaaaagg gactttattc tttttgtaac
    10321 ctttctgtaa taattctctg ccgaaaaaat gataaaatag gtatgtactg ttaaggagag
    10381 aattatgccc gtaagaaaat tacaatccta tgaggtagac tatcaagaag aattaaacca
    10441 gcagcttcct cattaccaag cttatacacc tgaagcgcaa tctgatgcca atctcaagga
    10501 aatcctattt tttattaata tcgctgtttt ttgtatctgt attgctatct ttagttttat
    10561 ctttttagca ttaaaattat caactgctct tgcctttgcc gcagcaatcg gattcagctt
    10621 acttgtttta aaagttcaac ggtctattat caaacgaaaa cgtagaagat aaatccaaaa
    10681 tatcgcccca gttggagcga tatttttatt ttttcttttt agatggtgtc tgaatggcaa
    10741 tcttcacttc aaagattgtt cccttgggtt tattatcttt gacagtaaca gttcctttta
    10801 gagcatctac aatttgcttg gctagggata atcctaaacc aaaaccacct ttttgccgag
    10861 ttctagcctt gtctactcga taaaaacggt caaaaatttt ctttttatct tctgtcgaaa
    10921 taccgattcc attatcagaa acaagtaaat aaagattgcg atcggtcgcc gagataagaa
    10981 aatcaatttc accatcctcc tcagtatact tgacggcatt atcgaaaaga atggtcatca
    11041 gttgtttcag aagaagctga tctgtgacaa ttgttcgatg gatacgattt tcaaaacgga
    11101 agacacgatt attttccgaa gcaatcatct cgtagtttgt gaaagttgta ttaaaaaagc
    11161 tagttggaac ttctgcaagc tccggcttaa tcccatcatc tctccgagct aagttcagca
    11221 agcttgtcgt taaaaaacgc atatttcgga cttcttccaa actcgatgca atgctttcgc
    11281 tcacatccat aatggtagct tctggcttac gaaaaagggt ctctaagcga ttttgcaaaa
    11341 ctgcgagtgg agttcgtaac tcatgactgg cattttccac aaaagactgt tgcttctgca
    11401 tactctcaag caggggccta acactgaccc tagctagata gagactggca agtaaagaca
    11461 aaatccagaa actagccatc acgaccacaa tcaattgctc atgcttttga ctagcctgtt
    11521 ccaactgact ggtattaatc aagacagcag catacttgat attggttgaa accgaactaa
    11581 tattggtctc catcaaaatc acacgataga tttcttcctg cccatagcta ttaaaaacct
    11641 gaatctggta gatatgtcct agttctttct tttctaactt aatcttatcc aagcccaaaa
    11701 atcgatttcc agaaagaagt tgagtaaagt ctttatcaaa gagaatgact tccgtattgg
    11761 aactgacatt aggttttatt tctactttac tagcgtccgc cctagcattt tctaaatctt
    11821 taatctcttc tgttgcccta tttatagcca gctgaataac tgcttgagga ttttcactca
    11881 gtccatgaag cttatcgtcc accgaagtat aaagactcga atgcatgact tgtaaaataa
    11941 tcagagtcat tgtagaaaaa atcagggtga agacaccgaa gttgcggata aaataactaa
    12001 agtcatccgc ataccatgtt tttttaagtt tactgaacat cttttaaaag atacccaaca
    12061 ctacgcaaag tttgcaaatt ctctgcaaaa gtggttccct ttaatttctt acggactttt
    12121 gaaacataga cttcgacaac cgaaatcgtt gtatcactat caaatcccca tagacggtca
    12181 aaaatctgcg tcttaggcaa aatcacattt tgattttgaa ggaaataaac tagtaaatcg
    12241 aactctttcc ccagcaattc gacaggagta tcttcaactt taacggtatt ggttgataaa
    12301 ttaaccacga tattcccata agtcaaggtg ttttcattaa acttccctga acgtttgaga
    12361 agggcctgaa tccgcatttt aagttcttct aggtagaaag gtttggtcag ataatcatcc
    12421 gctcccagtt caaatccatg tcccttgtca tccaaacttt ccttggcagt cataatcaga
    12481 actggtgtcg taattccctt ttcacgcaat tcttttaaga cttggaaacc atttttttct
    12541 ggcaacatca aatccagcaa aatcaagtca tagacaccac tctcagcttc gtagagacct
    12601 tcttctccat caaatacctg cataacatcc gcaaaatcgt ctaaaaagtc aaatactgaa
    12661 tttgacagac ctaggtcatc ctcaaccaat aagattttta tcatgagaaa ctcctcctta
    12721 ttaaaactat tataccaaat ttgccttaaa aaaaactcaa ctctctgcat tttacatgag
    12781 atagctgagt tttcttttta ttttaggctt atttatgcat ttccgtattg aagaacaact
    12841 gcttcgactg cagctttttc acggctaatc aagtcaacac gcgctgcaat ttccttgatt
    12901 cccataccga tgttacggct aagagcaagg tcagaaagtt gcggctcaaa gaactccttg
    12961 tattccgcca agcgttgctg agtcttaaat acatgagcag gaaggataac aaagctatca
    13021 aagctcatat ctcctccaag ggctgcctta atccaagccc agttttcacg cgcccaagac
    13081 caagctgttt tctgagttgc ttgatgagct aggaattggt aataccaagc agacaagtcc
    13141 tgtggtttga ccacaaattt gtccttccaa gaagtaatca agttttggat attatccgca
    13201 tctgtactgt atgcaagagc tgctgccaac tggcgtttaa agacagcatc tgttgcgtga
    13261 gtataagtat caagataaag tgctaacaag tctttagtct catgatgttt catctcatta
    13321 atcagaactt gtgaacgaat agctgctggg agtcctgcaa gattctcctt gtgtgttgcg
    13381 aagatttggc tagcgacttg actagcttct gcatcatttg agcgaatcat catcgaaaca
    13441 gccagctgac gaaccaattc atcctcatct gattctccgt ctttagcttc aaaaccaaga
    13501 cggtcatagt tatgacgagc caatttagca accagtcctt tgaaggctgt ttcagcatcc
    13561 gttccttcat caataaagcg ctcaagggct gaaatcactt gagaaacagc tgaaaccacc
    13621 agataagact cttccttagc aagtttatca agaactggaa gcaagtctgc ataagcaatg
    13681 tgccctgcct cagccaacaa acgacgttct tgaacaattt gcagtttgct tgtgttatca
    13741 agtgtctcta gctcagcaag aacagcttct aacaagtctc cttgatagtc ggtaatatag
    13801 tgggcagtat tttcagtgtt gagacgaaga gctccttcat tttcagcaag aagagctgcg
    13861 tagccaggga tttcgatact ttcagtttcg agtgtatcag gcaagccttt ccagttgcta
    13921 ttgaggggca ccacccagag acggttcttg tcttcgttct caccgatgaa gaattgtttt
    13981 tgtgaaatct tcaagacatc attttcaact ttaacagtaa gaactgggta accaggctgt
    14041 tccaaccaag aatccatgaa ggctgcgaca tcacgtcctg acgcttgacc aagggcatcc
    14101 caaaggtcac taccaatggt gttgctgtat tggtgttttt caaagtaggc gtgcaaacct
    14161 ttagcaaaat cagcatctcc tagccaacgg cgaagcatgt gcatgagacg gcttcctttg
    14221 gcatagacga tagcgccgtc aaagagtgta ttgatttcat ctggatgttt aacttcgacg
    14281 tggacagact gaacgccatc agtagcgtca cgttcaagag caagaggtac tccacctgtt
    14341 tggaaatctt caaagatatt ccagcttggt tcgatggtat ccacacagac gtattccatc
    14401 atattagcga aactttcatt gagccaaagg tcatcccacc atttcatagt cacgaggttc
    14461 ccaaaccatt ggtgagccaa ttcatgggcc acaacaaggg caacttgttg acggctagca
    14521 aatgtagagt tctcatcgac aaccaagtaa acttcacggt aggtcacaag accccagttt
    14581 tccatagcac cagctgagaa gtcaggaagg gcgatgtgga gagattgagg aattgggtac
    14641 ttaactccat agtaatcttc gtaaaactcg atagagcgaa cagcgatatc cagtgagaaa
    14701 tcaagatttg aaagtggatg tgctttggtt gagtagacac ctaccagggt accattttta
    14761 gttttagcgg tcaccccttg caaatcacca gcaacaaagg ccaacaagta agaagacatg
    14821 cgaggtgttg tctcaaactt ccagatacct gtttccttac ggttttcaac atcgatttct
    14881 ggcatgtttg acaaggccaa ttcaccttct gcttggtcaa agcgaagaga gaggtcaaaa
    14941 gttgctttgg cttcaggctc atccacacat gggaaagctt cgcgcgcaaa atggctctcg
    15001 aactgagtag acaagacctc cttcttgact ccatcaactg tataataaga agggtaaatc
    15061 cctgtcatgt tgtctgtaat tttaccagaa aaggcaagaa ccaattcaac ttgaccagcc
    15121 tcagccaatt cgatatgaag ggcttcattg tcatggtcaa ctgtaaatgg acgagcttga
    15181 cctgcaactt ctacagaggt gatttccaag tctttttggt ggagggagat gcggtcactc
    15241 tgtgcttgac cagtgatggt cactttccca gaaaaagtct tggtctcacg actcaaatct
    15301 aaaaataaat cataatgttc aggaacaaat tgcttaataa aatgttcaac tgcttgcata
    15361 gttttctcct attctaagtt taagagctac tgctcttctt caaacaaact tattatatca
    15421 tattttgctt gagaaaaaag gattggacag cgatttccaa aactttcttc cttctaaata
    15481 gtctacagtg ggtagacctt gcgaaattct tctaaaacaa ccttgctttc aggtgtaaaa
    15541 gtcagcccta cttcacccaa acagtctgtg aaaaagtcct catgaacctg gcgccaatag
    15601 gcaagtgatt tgtctccctc accttcctta aaggcatgtt gcgcagaaac ttgattgaag
    15661 agttcaacag aaacctttgt aatttcgaca atgcagacag actgattttg actatctaaa
    15721 atgacatcga aggtccctac ttggggaagt ggttcgtctt ctagtacata gaggtcatag
    15781 gctgatgctg ttgctgtctt ttctccttta aacaccaaat ccgctaaaag gtctggttca
    15841 actccaaaag cccaagcatc gatttcatct ccgatcaaag gattgatttg cttgtattta
    15901 ttccacattt cttgcggtat catgggtact cctttgtaat tttttacttt cttcttttat
    15961 gtgtttaaga tgatctggat ggtcaatctc taaatcaaaa atctctggaa tagaactgta
    16021 gtggataatg cacttgatac ccaactgatt cattttttgt atgaaagaag tattcagata
    16081 gcctgctaca gcaaaattaa tcttgttctt tcttgcttta tcctgcatat ctcttagcat
    16141 atctaacatt attggacttt ccagatcatg ccattgactg tttctcatag tcgcaaaaac
    16201 aaaggaagtc aaatcattca ttccaactac aatctttgaa atgcccgttt ccagtatact
    16261 agataagtca aaatacgctg acggtaattc aatcatcgtt ccgactttcc cagtaaagcc
    16321 atactgacgc aatactgtaa tagcttgttt taattggtcg gcatcattga caaaaggaaa
    16381 gataacagat agattggggt tggtttgata aacttctgta acgacatgtg cttcagcctg
    16441 aaattcatcc aaacacgcca gtaaacgcct ggttcctcta tagccaaaca agggatgccc
    16501 ttcgtcaaaa aactctttag tccccactaa acaattggct tctgtattcg ttaattcagt
    16561 aaaacgatac caaacttctt catctgagta cagggagcag atagtctcta gataatcttt
    16621 tacaaattgc tgacaacttg ctaatatgat gttttgatta agctctctca acaaatattc
    16681 cccacgaatc atgccgacgt ggtgaaatag ttgaggataa attttttcaa gaattttttc
    16741 gccactaagg gcaagttgat ttctcatagc cattcacctc gtcttaaaag atacaatatc
    16801 atatataatt atatcaaaat ttcctctagt tcaaaagctt cataaggttc agataactca
    16861 tatcctaaaa attctgctac ttttttggaa gcctcattat gagcatccca aagtggaaac
    16921 atatctctat ttaaactctc tagaatcatt gcagcaccaa gctttttagc aaatccattt
    16981 ccttgttcgt ttggtctagt tgcaacttcc acttcaactg ctttacggta aactaaccct
    17041 gaggaaatcc cagcaatcag ttcattattt ttaagaatca caaagccaaa tccacctttt
    17101 aaaacaaaat cctgatagga ctcaaaatcc ccctgtaaat cctgtgacca ttcttccgta
    17161 gaaaagcagt tataaatatg attatcaata ggcacaatat tgtaaccttc ctctaaatga
    17221 gtaactagat tatttaaaaa ttcaacttga aaatttgcct tatctttaaa agaatagcga
    17281 gtaaaagaat ttagccccac ttttcgatgc agaaaatctt gccaattagt attttctgaa
    17341 ataataatct tataatctaa accatatttt ctaacaaaat cttcccaaaa tctggaatcc
    17401 aactcccctg ctaggtatag aaaattccca acatcataaa agcttgttgt cctatcattg
    17461 tttcggtaga cagttccaat ttgagattta agaccataga gaaccatatt tttcttccat
    17521 gttttaaata gttccattat ccctctactt caccttccaa ttcatgtaag aagtcttgtc
    17581 cagttctgga aatcctaata attcagactt aaccttcaag actaatggcg atgcattttc
    17641 ttctgtaatc tcttgaatat ccatccaaat atatccaagt gaatcattcg caccatcaga
    17701 cacagcttcc gaagtcgtaa cttgaggtgc actctcattc atttcaacat catacaaggc
    17761 catgacatgg tcaaccataa aatttgttaa ctcttctctg acgaaaacat cgtagattcg
    17821 aggattagag tagcttctaa cagtaaatcc cgtctcttcc ataacttctc tagtcagcgt
    17881 ttccgtcagt ccttcaccaa gttgctgact gcctccaggt agatcatacc gatgttgata
    17941 agggcctctc gttttttcaa tgcagagtaa cttcccattt tctaagcaaa cagcgtagac
    18001 tccaaagtgt tttttgattt ccatccaact cctcctactt caaagaccag ccaccatcta
    18061 ttgtcaagat ttgtccttgc atggcgctcg cttttccact tgctaaaaaa agactaagct
    18121 ctgctatttc ctctggctca atccagcgct tgattggagt ttcactagcc acccagtcag
    18181 ccaaaccacc tggttcaaaa tccgcagcgg tcatagctgt cttgactgct cctggagcga
    18241 taccaaagac ctgaatccca gcttcagcat agtctagagc caactgcttg gtgaagccag
    18301 ccaaggcatg cttggatgaa gtataggcgt gaccacctcc acctgctagg ctagaagcaa
    18361 tggaacacat attgatgatg attccctttt tattttccag catttgtgtc aaataatacc
    18421 gagtcaactc tactggaata atgtagttga tttcaaaaat ctcttgaatg tcctgcgccg
    18481 tttgttccaa cagtggtttg taatcatcca aaactccagc agtattacac aaaacatcca
    18541 cctgagggca ccagtcaaaa ataggttcca agtccaaggt caaatctctc tgtaaaaagt
    18601 gaaaatcacc ctctaagagt ggcttttcac cttggtcaac tccataaact tgatagccct
    18661 tctctaaaaa gaggcgagct tgagccaatc cgatccctga actcactcct gtaatgagta
    18721 cacgtttagt catgcacttc tacccaatcc gttgccaaaa catcacaaac tgtcgggctc
    18781 cacatggaaa aaccttctcc ttcgccagaa acgttgatta ggaaataagg tgtcatttca
    18841 agtgcaagcc cattttgctc gatggtatca aagagttgga catagttttc cgcacctccc
    18901 caaccagttc gtacatattt tctcttagcc tttaacccag gcaggatctc ttcaaatgtc
    18961 atgtttttct cctttaattc tacattcttc atttaattat agcaaaaaac cgctttatac
    19021 ggctttttga atgtgagtta ttcaaacctg ctactactta cggcaaatta ttccctgcag
    19081 caagataaat ttcataccat tcttttcttg ttaagctaaa gtttgccgct cggctaactt
    19141 ctctcaagtg cttaggattt gttgtaccta cgactgcctg catttttgct ggataacgca
    19201 atatccaaga aatggcaata gttgaagagg ttactccata tttaatagct aaacgatcaa
    19261 gtacttgatt taaagcttga aatttctcat ttccaacaaa attcccttta aaatacccga
    19321 attgtaagac agaccatgct tgaatgacca catcgtgtaa ttggcaatat tcaaaaatgc
    19381 tgccatctcg catagctgct tgactatctt ccatattaac atgaaaagct gattcaaatc
    19441 ctggagtaaa agccgcactc aattgtagct gattaacagc taacggctgc ttgacatctt
    19501 ttttaagcaa ctccatcatc ataggatttt gattagaaac tccaaaatct cgaactttac
    19561 cttgtttata aaggagatta aaggcttctg ctacttggtc agattccatc aaagcatctg
    19621 gtcgatgaag gagcaagcta tctagatgat caatcttcaa tctttgcaaa ataccgtcta
    19681 ctgattttat aatatagtcc ttagaaaaat caaaataggt aaattcttca atgcgaatgc
    19741 cacatttgga ctgaatccac atcttttctc ttaaatctgg acgatttttt aggacaagac
    19801 ctaacagttc ttcacaacga ccacgaccat aaatatcagc caagtcgaag gcattgattc
    19861 caacagaaag tgctgtttct acaagctctt caacttcttt tacagactta tcttttattc
    19921 tcatcattcc gagaacaatt tctgataatt ctttgtcatc ttgaccaaga gttatgtatc
    19981 tcatcaaatt tttctccttt aatttctaac attcttccct tcattataac aaaaaaccgc
    20041 tttgcaacgg ctttttgact atacttcact ccattttatc ttcttaaacc cacggaacaa
    20101 gacaaagatt ccaataaaga ggacagctaa aggaataact tttgtaagga aaacatttga
    20161 aattcccatc cactcataat aacggagcag agaacccacc acaagatggg caataatcat
    20221 actgacaaat ggacgaaaga ccgcttcttt ccaattccaa ataccgataa ctagcgaaat
    20281 cgtaaagaca gacaaactat cccagggagc cggaatataa aaggctcctt cttgtatgaa
    20341 gcttgccatt cctacatatc ctaaaacaac tagaagaact atagtcccaa caacaatgta
    20401 agtgccaatt ttcattttag gagaatcttg gactaaactt cttcgtaaaa ttgtggccac
    20461 aagtccaaat ccaatcagaa aaataagaag ttgccctaaa aatgtgagca aattgactgt
    20521 taagagagga cctttagaaa aatcacttag tagttgataa taacgtaata cagccaggac
    20581 aagaattggc gtcaaaaggg actctttgat agaactgcga ggtgctccct tgagaatctc
    20641 tttcattatt tttttaggat tcttacctag ataatcctct gcactcatgc catctcgttc
    20701 tgcttctgag aaatctagca tcatcaaata gatctgctct ctgagatagt cttcatcata
    20761 gagaaatcca gcaagattaa aactttccca caactcctca aaatactttt gattctcctc
    20821 agaaaactca tgtagcaaag cgcttgtttc ttcgtaatac ttcattttct tcatggttta
    20881 acccccattc ttaatccctt ctactttttg actcaaatcg tcccattgct gccaaaagac
    20941 tgagacacgc tcttctcctt ctttcgttaa tgaaaaatac ttccgatctg gaccatctgg
    21001 cgacgggcgc atgtcgcctc ttatccattg atttttttct aacttttgca acaaaggata
    21061 aatagttcct ggaacgatag tatcaaatcc agcctctcgc aaagtctgaa ccaactcata
    21121 accataccgc tctttttgac caatcatatc caagacacaa ccttcaagaa caccttttaa
    21181 tagctgagtt tctttcatca cttctccctt ctaatctatt ttgtaatacc tactagtaac
    21241 ttcacctata gtatattact tctacactag tttgtaaagc ataatagtta atactcttcg
    21301 aaaatctctt caaaccacgt cagcgtcgcc ctaccgtatg tatggttact gacttcgtca
    21361 gtttcatcta caacctcaaa acagtgtttt gagctgactt cgtcagtttc atctacaacc
    21421 tcaaaacagt gttttgagct gacttcgtca gtttcatcta caacctcaaa aacatgtttt
    21481 gagctgactt cgtcagttct atctacaacc tcaaaacagt gttttgagca acctgcggct
    21541 agcttcctag tttgctcttt gattttcatt gagtataaat aaaaaaacag aactagtctg
    21601 aactagtcct gtctactttt acccaatcac acttccattt ggtacagctg gatcaactgt
    21661 gagaagggtt aatttgccat catattcagc tgatagaatc ataccctggc tgacatattt
    21721 tttcatcatt ttacgtggtt tgaggttagc aacgatttga actttcttgc cgaccaattc
    21781 ttgttcattt ggatagtatt ttgcaattcc tgaaagaatc tgacgatctt ctccatcacc
    21841 agcatccaag cggaattgaa gcaacttatc tgaaccttct actttagaca cttctttgac
    21901 ttctgcgaca cggatttcaa ccttgtcaaa gtcttcaaac ttgatttcat ccttgtttag
    21961 tttgagctca acttcgtccg gattccattc tttttcgact gctggtttat tgccttccat
    22021 ttgttccttg atataggcga tttcttcttc catatttaga cgtggaaaga taggtgttcc
    22081 tttggcaact acagtcacat ctgctgggaa gtcagccaaa ctcaagtttt caagactaga
    22141 aacttcttcc aaaccaagtt gagtcaaaac tgcacgacta gtttccatca taaatggttc
    22201 aatcaagtga gcaactacac gaatgctggc tgccaagtgg ctcatgacac ttgccaattg
    22261 gtcacgaaga gcttcatcct tggccaagac ccatggtgcg gtctcatcga tgtatttatt
    22321 ggtacgagag atcagagtcc agactgcttc aagcgcacgt ggatagtcaa ctgcttccat
    22381 gtgtgtatgg aagtctgcga ttgattgttc tgcaacctca gcaagaacat gatcaaattc
    22441 agtcacacct tctacatagg cagggatttg tccatcaaag tacttattaa tcatggaaac
    22501 cgtacggtta aggaggttcc caaggtcatt agccaattca tagttgatac ggccgacata
    22561 gtcttcagga gtaaaggttc cgtctgaacc aactggaagg ttacgcatga ggtagtaacg
    22621 aagtggatct agtccataac gctctaccaa catttcaggg taaacgacat tcccttttga
    22681 cttagacatt tttccgtctt tcatgacaaa ccaaccatgg gcaatcaaac gatcaggtaa
    22741 tttaacatcc aacatcataa gaaggattgg ccagtagata gagtggaagc gaaggatatc
    22801 ttttcctacc atatggaaga ctgttccatt ccagaacttg tcaaagttac catgttcgtc
    22861 ttgagcgtag ccaagagctg tcgcatagtt aagaagggca tcaatccaaa cgtagacaac
    22921 gtgttttgga tttgatggga caggcactcc ccatgtaaag gttgtacgag ataccgccaa
    22981 atcttccaag cctggctcga tgaagttgcg tagcatttca ttaaggcgac catctggcgt
    23041 gataaattca ggatgagctt tgaaaaattc gaccaaacgg tcttggtatt tgctaaggcg
    23101 aaggaagtat gattcttcag aaacccattc aacctcatga cctgatggag caataccacc
    23161 agtcacattt ccagcttcat cacggaaaac ttctgccagc tggctttctg taaagaattc
    23221 ttcgtctgat actgaatacc aaccagagta ttcacccaag tagatatcat cttgagcaag
    23281 taagcgttca aagacctgtg cgacaacttt ttcatggtag tcatcggttg tacggataaa
    23341 tttatcgtat gagatatcta gtaattgcca gagttcttta actccaaccg ccattccatc
    23401 aacataggct tgaggtgtaa taccagcttc ttccgctttc tgctggattt tctgaccatg
    23461 ttcatcaaga cctgtcagat aaaatacatc gtagcccatc aggcgtttgt aacgtgctag
    23521 gacatcacat gcgatagttg tgtaggcaga accgatatga agtttcccag atggatagta
    23581 aatcggcgtt gtaatataaa aatttttttc agacataatt tttcctttcc aggcaaatga
    23641 aacctgtttt tctaacactt cattatatca catttttaat gaatttcgat agggaaatcc
    23701 atacaaaaac aagatagacg agtgtccatc ttgttgatct cattcataac gaagggcttc
    23761 aattggatca agtttcgatg ccttgttggc tggcaagact ccaaaaatca taccaacact
    23821 agccgaaact gcaagactaa atagggcaac tgggattgat actccaactt ctataccttc
    23881 tattaaacct tgcagtaaca aacctgctaa ggcagttaaa ccacttgcaa ttgtcaagcc
    23941 aattaagcca cctaacaagg tcaaaatcat ggattcaatc aaaaactgaa ttaaaatatt
    24001 ggcacgtgtt gcacccaaag ctttacgaag accaatctca cgagtgcgct ctgtcaccga
    24061 aaccagcatg atgttcatga caccagttcc tccaacaaag agagaaatcc ctgcgatgga
    24121 actaataatc gtcgtcataa aactaaacga ttgttgaatt tctgcaaata caacggactc
    24181 atctgccacc tggtattctc cctgttgtaa gcctgcaagc tctgtcattt ttcgtgccag
    24241 ttctggaccc agagttgggg ttaaactggt atcattcact cgaaagacaa tactagctat
    24301 ttcatctata ttaaaattcg cagcaaggga gatattggta gtaataggca agccaccaaa
    24361 cccatatatt tttgactttt tagcctccgg actagtataa accccaatga cccggtaact
    24421 aaatccattg acttctacaa ccttgttaat agcctcttga ggagattcaa ataaactaat
    24481 ggacaattcc tcatctagca aaataacact tgcaaactct ttgaaatctt gctctctcag
    24541 actacgacct gcaataattt cattcttaac agcgtccatg taagttctgt ttccacctgt
    24601 caaattagca ttctcaacct ttttatcttg ataggtcaag atggcattcg ttgaattggt
    24661 tacatagtaa ctatccactc ccttcagttt agctgcctct tgaacccagg attcttgcgg
    24721 ttttggcggt tcaacaggaa cttcctcttc ctttccagaa accgtaaaag ctgattgttt
    24781 ctgagtaaaa gacccatctt tacttttttt aggagagaaa aagacgctaa tatttttctg
    24841 agatttagtc atatctttat tgacttgacg agatagggaa tcacccaaag ccataatcac
    24901 aacaactgat gaaacaccga taataatccc aatcatagta agcaaagaac gcatcttgtg
    24961 agccatgata gatgaaaagg caaatttcag attctgcatc ttagttttcc tcctttccta
    25021 actgagcact gtcagacgaa atgaccccat cccgaatgac aatctgacgt ttggcatagg
    25081 cagcaatctc aggctcatgc gttaccatga taatggtttt tccttcttta ttcaaatcaa
    25141 ccaataattg cataatttgg ttacctgttt tggtatccaa ggctcctgtc ggttcatccg
    25201 ctaggataat agaaggattg tttaccaagg cacgcgcaat ggctacacgt tgcttttgac
    25261 caccagataa ttctgaaggt aaatggtgac tacgttctgt caattcaacc ttgtctaaat
    25321 attcctcagc caacttgcga cgttttgaag acgaaactcc tgcgtaaatc aagggcaatt
    25381 ctacattttg cagagcattg agcttcgata gaagaaagaa ctgctgaaag acaaaaccga
    25441 tttgttggtt acggacctta gctagttgtt tttcaccaag cccagccact tcttgacctt
    25501 caagataata ttctccactg gttggtgtat ccaacatgcc aatcgtattc atcagagtgg
    25561 acttaccaga cccagatggt cccatgatgg ctacaaattc accctcattc acttctagat
    25621 tgatattttt gagaacctgc agttcttggt caccattacg gtaacttctg aagatatttt
    25681 ttagactaat tagttgcttc atcagccttc acctcttttc cttcttccaa ggaagatgtt
    25741 ggattactga tgaccttagc accgttcgtt aaaccagaag tgatttcttg attttctgcg
    25801 tcagcatttc ccaatgaaac ctcaactttt ttagcctttt gttgttcatc cacaatccag
    25861 acataatttt tactatcatc cattactaga ctgctaacag gaataagaat agccttagtt
    25921 ttgcttttaa cctcaatgtt gacagaaaaa ccttgtttca aatcaccaac ctcgcctgtc
    25981 acatcaatag tataagggta tttagaacct gtattattcc cggctgctgg actagctgct
    26041 tcaccattgt ttttaggata gtcagaaata tagcttaatt tcccagtcca ttttttatca
    26101 ggatacactt tagaagtaaa gcttacttct tgacctacag aaaggttggc tagattgtac
    26161 tcagacaatt ctcccttgac ttgtaaattt tcattgctga caatatgaac cataacttga
    26221 ctcgcccctg ttggagattt agaaacattg ctattgactt cgactacagt tccctctagg
    26281 gtactgagaa cagttgttgc atccaattga ctttgagcct tgcttaattg cgctgcagca
    26341 tctgcacgcg catcacgggc atcacccaat tgagcatcaa tagaagcaac agaatttcca
    26401 gccactggag ttgggctttg caccgttgca tcttctcctc ctactggcgc tggtaactgt
    26461 ggagcctgag ctgaagcggc ttcatttcgt gcttgattga gttcattgat atgacgatct
    26521 gccttagcta ctgctcgact agctgaatca taggccgcct gcgcttctga actactgtac
    26581 ttgactaaag cctgcccttc gctgacctta tcgcccacag aaacaaggat ttcatctaaa
    26641 tcacccttac tagcatcaaa ataaacatat tgttcatttt ttgctgttac tgtccctgac
    26701 aataaaacag aggatgccac gcttccttcc ttggcaacaa caagatgagt aggctcatct
    26761 tttacagcag tctgagaagg ttgtctaaaa agtaaaatcc ccccggcacc caatacaact
    26821 acactcgcag caccgattgc tgcatacagt tgccactttt tagctttacc attctttttc
    26881 ttcataatga aactcctttt cttttttaca atactttgct attataccaa atttccctcc
    26941 agcaaacaat gcagttcaga tggaaataat ggcagttcag gattaaacaa tcgttcggaa
    27001 ttttgctttt ctattgtact agatatataa tacactatct tgacttattt ggcaagcttt
    27061 tttgcaattt tttgtgcgta gcagattttt gcaatcaaat caaaaaaaga ataaaatata
    27121 actatcaaaa aagacactct actatttaaa agattacaaa ggagttttca atgagagaat
    27181 atgatatcat tgctatcggt ggaggtagcg gaggaatcgc taccatgaac cgtgctggtg
    27241 aacatggagc caaagcagcc gttattgagg aaaagaaatt aggtggaacc tgtgtcaacg
    27301 tcggttgtgt tcctaaaaaa atcatgtggt acggggcgca aatcgctgag actttccatc
    27361 aatttggaga agactacggc tttaagacta ctgatcttaa ctttgacttt gcaaccctac
    27421 gtcgcaatcg tgaagcctac attgatcgcg ctcgttcttc ttatgatggt agttttaaac
    27481 gcaacggtgt agacttgatt gaaggtcatg ctgaatttgt agattctcat actgtaagcg
    27541 taaatggtga actgattcgt gctaaacata tcgtgattgc tacaggtgcc catccaagta
    27601 ttcctaatat tcctggtgct gagctaggtg gctcttctga tgatgtattt gcctgggaag
    27661 aacttccaga gtcaattgcc attctaggcg ctggttatat cgccgttgaa ttagctggcg
    27721 tactccacac ttttggtgtc aagacagatc tctttgttcg ccgcgatcgt cctttacgtg
    27781 gttttgattc ctacatcgtt gaaggtttgg tcaaggaaat ggaaagaaca aacttaccac
    27841 ttcacactca caaagtccct gtcaagttag aaaaaactac tgacggcatt accattcatt
    27901 tcgaagatgg tactagtcac acagctagcc aagttatctg ggctacaggt cgccgtccaa
    27961 acgttaaggg cttgcaactt gaaaaagctg gagtgactct gaacgaacgt ggctttatcc
    28021 aagtggatga ataccaaaat actgttgttg agggaatcta tgctctaggt gatgtaacgg
    28081 gcgagaaaga actgactcca gttgcaatca aggccggacg taccctatct gaacgtctct
    28141 ttaacggaaa aactactgca aaaatggatt actcaactat tccaactgtt gtcttttcac
    28201 accctgctat cggaactgtt ggtttgacag aagagcaagc tattaaagaa tacggtcaag
    28261 accaaatcaa ggtttataaa tcaagctttg catctatgta ctctgcttgc actcgcaacc
    28321 gtcaagaatc ccgtttcaaa ctcataacag ctggttcaga agaaaaagtt gtcggacttc
    28381 atggaattgg ctacggcgtt gatgaaatga ttcagggatt tgccgttgct atcaaaatgg
    28441 gagcaaccaa ggctgacttt gatgcaactg tggcaattca cccaactgca tctgaagaat
    28501 ttgtaaccat gcgttaatcg aaacaaaaga agctgatata aatatgtctg cttcttttt
//
LOCUS       DAVBDR010000024        28449 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.024, whole genome shotgun sequence.
ACCESSION   DAVBDR010000024 DAVBDR010000000
VERSION     DAVBDR010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 28449)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28449)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28449
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.024"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            418..1371
                     /locus_tag="VQ540_001057"
     CDS             418..1371
                     /locus_tag="VQ540_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000345081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HET2544871.1"
                     /translation="MDFEKIEQAYTYLLENVQVIQSDLATNFYDALVEQNSIYLDGET
                     ELNQVKDNNQALKRLALRKEEWLKTYQFLLMKAGQTEPLQANHQFTPDAIALLLVFIV
                     EELFKEEEITILEMGSGMGILGATFLISLDKKVDYLGMEVDDLLIDLAASMADVIGLQ
                     AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYAHHLLMEQGL
                     KYLKSDGYAIFLAPSDLLTSPQSDLLKEWLKEEASLVAMISLPENLFANAKQSKTIFI
                     LQKKSEIAVEPFVYPLASLQDASVLMKFKENFQKWTQGTEI"
     gene            1422..2612
                     /locus_tag="VQ540_001058"
     CDS             1422..2612
                     /locus_tag="VQ540_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HET2544872.1"
                     /translation="MTKTIAINAGSSSLKWQLYLMPEEKVLAKGLIERIGLKDSISTV
                     KFDGRSEQQILDIENHTQAVKILLDDLIRFDIIKAYDEITGVGHRVVAGGEYFKESTV
                     VEGDVLEKVEELSLLAPLHNPANAAGVRAFKELLPDITSVVVFDTSFHTSMPEKAYRY
                     PLPTKYYTENKVRKYGAHGTSHQFVAGEAAKLLGRPLEDLKLITCHIGNGGSITAVKA
                     GKSVDTSMGFTPLGGIMMGTRTGDIDPAIIPYLMQYTEDFNTPEDISRVLNRESGLLG
                     VSANSSDMRDIEAAVAEGNHEASLAYEMYVDRIQKHIGQYLAVLNGTDAIVFTAGVGE
                     NAENFRRDVISGISWFGCDVDDEKNVFGVTGDISTEAAKIRVLVIPTDEELVIARDVE
                     RLKK"
     gene            2761..3132
                     /gene="rnpA"
                     /locus_tag="VQ540_001059"
     CDS             2761..3132
                     /gene="rnpA"
                     /locus_tag="VQ540_001059"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HET2544873.1"
                     /translation="MKKNFRVKREKDFKAIFKEGTSFANRKFVVYQLENQKNHFRVGL
                     SVSKKLGNAVTRNQIKRRIRHIIQNAKGSLVEDVDFVVIARKGVETLGYAEMEKNLLH
                     VLKLSKIYREGNGSEKETKVD"
     gene            3107..3931
                     /locus_tag="VQ540_001060"
     CDS             3107..3931
                     /locus_tag="VQ540_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HET2544874.1"
                     /translation="MKKKLKLTSLLGLSLLIMTACATNGVTSDITAESADFWSKLVYF
                     FAKIIRFLSFDISIGVGIILFTVLIRTVLLPVFQVQMVASRKMQEAQPRIKALREQYP
                     GRDMESRTKLEQEMRKVFKEMGVRQSDSLWPILIQMPVILALFQALSRVDFLKTGHFL
                     WINLGSVDTTLVLPILAAVFTFLSTWLSNKALSERNGATTAMMYGIPVLIFIFAVYAP
                     GGVALYWTVSNAYQVLQTYFLNNPFKIIAEREAVVQAQKDLENRKRKAKKKAQKTK"
     gene            3950..4936
                     /locus_tag="VQ540_001061"
     CDS             3950..4936
                     /locus_tag="VQ540_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein jag"
                     /protein_id="HET2544875.1"
                     /translation="MVVFTGSTVEEAIQKGLKELDIPRMKAHIKVISREKKGFLGLFG
                     KKPAQVDIEAISETTVVKANQQVVKGVPKKINDLNEPVKTVSEETVDLGHVVDAIKKI
                     EEEGQGISDEVKAEILKHERHASTILEETGHIEILNELQIEEAMREEAGADDLETEQD
                     QTENQDLKEMGLKVEQSYDIAQVATDVTAYVQAIVDDMDVEATLSNDYNRRSINLQID
                     TNEPGRIIGYHGKVLKALQLLAQNYLYNRYSKTFYVTINVNDYVEHRAEVLQTYAQKL
                     AIRVLEEGRSHQTDPMSNSERKIIHRIISRMDGVTSYSEGDEPNRYVVVDTE"
     gene            4987..5610
                     /locus_tag="VQ540_001062"
     CDS             4987..5610
                     /locus_tag="VQ540_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P"
                     /protein_id="HET2544876.1"
                     /translation="MLNKIRDYLDFAGLQYRNPDKAGAEREKMLAFRHKGQEARKAFT
                     ELAKAFQASHPGWQLQQTSQWMNQAQRLRPHFWVYLQRDEQVTEPMMALRLYGTSTDF
                     GISLEVSFIERKKDEQTLGKQAKVLDIPTVKGIYYLTYSNGQSQRWEANEEKRRTLRE
                     KVRSQEVRKVLVKVDVPMTENSSEEEIVEGLLKSYSKILPYYLATRK"
     gene            5741..7198
                     /locus_tag="VQ540_001063"
     CDS             5741..7198
                     /locus_tag="VQ540_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HET2544877.1"
                     /translation="MEVVSSVLNWFSSNILQNPAFFVGLLVLIGYALLKKPAHDVFSG
                     FVKATVGYMLLNVGAGGLVTTFRPILAALNYKFQIGAAVIDPYFGLAAANNKIAAEFP
                     DFVGTATTALLIGFGINILLVALRKITKVRTLFITGHIMVQQAATVSLMVLFLVPQLR
                     NAYGTAAIGIICGLYWAVSSNMTVEATQRLTGGGGFAIGHQQQFAIWFVDKVAGRFGK
                     KEESLDNLKLPKFLSIFHDTVVASATLMLVFFGAILLILGPDIMSNKEVITSGTLFNP
                     AKQDFFMYIIQTAFTFSVYLFVLMQGVRMFVSELTNAFQGISNKLLPGSFPAVDVAAS
                     YGFGSPNAVLSGFTFGLIGQLITIVLLIVFKNPILIITGFVPVFFDNAAIAVYADKRG
                     GWKAAVILSFISGVLQVALGALCVALLDLASYGGYHGNIDFEFPWLGFGYIFKYLGIV
                     GYVLVCLFLLVIPQLQFAKAKDKEKYYNGEVQEEA"
     gene            7221..7502
                     /locus_tag="VQ540_001064"
     CDS             7221..7502
                     /locus_tag="VQ540_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET2544878.1"
                     /translation="MVKVLAACGNGMGSSMVIKMKVENALRKLNQTDFTVNSCSVGEA
                     KGLAVGYDIVIASLHLIQELEGRTNGKLIGLDNLMDDKEITEKLSQALQ"
     gene            7579..8064
                     /locus_tag="VQ540_001065"
     CDS             7579..8064
                     /locus_tag="VQ540_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET2544879.1"
                     /translation="MNLKQALIDNDSIRLGLEANNWKEAVKVAVDPLIESGAILPEYY
                     DAIIESTEEYGPYYILMPGMAMPHARPEAGVQSDAFSLITLQNPVVFSDGKEVSVLLA
                     LAATSSKIHTSVAIPQIIALFELEDSIARLQACQTKEDVLAMIEESKDSPYLEGLDLE
                     S"
     gene            8081..8746
                     /locus_tag="VQ540_001066"
     CDS             8081..8746
                     /locus_tag="VQ540_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HET2544880.1"
                     /translation="MTKRIPNLQVALDHSDLQGAIKAAVSVGQEVDIIEAGTVCLLQV
                     GSELAEVLRSLFPDKIIVADTKCADAGGTVAKNNAVRGADWMTCICCATIPTMEAALK
                     AIKTERGERGEIQIELYGDWTFEQAQLWLDAGISQAIYHQSRDALLAGETWGEKDLNK
                     VKKLIDMGFRVSVTGGLDVDTLKLFEGVDVFTFIAGRGITEAADPAGAARAFKDEIKR
                     IWG"
     gene            8750..9613
                     /locus_tag="VQ540_001067"
     CDS             8750..9613
                     /locus_tag="VQ540_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000252119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HET2544881.1"
                     /translation="MVRPIGIYEKATPTHFTWLERLNFAKELGFDFVEMSIDERDERL
                     ARLDWSKEERLEVVKEIYETGVRIPSICFSGHRRYPLGSKDPVLEEKSLELMKKCIEL
                     AQDLGVRTIQLAGYDVYYEEKSPQTRQRFIKNLRKACDWAEEAQVVLAIEIMDDPFIN
                     SIEKYLAIEKEIDSPFLFVYPDIGNVSAWHNDIYSEFYLGHHAIAALHLKDTYAVTES
                     SRGQFRDVPFGQGCVKWEEAFDILKETNYNGPFLIEMWSENCETVEETRAAIQEAQAF
                     LYPLIKKAGLM"
     gene            9615..10319
                     /locus_tag="VQ540_001068"
     CDS             9615..10319
                     /locus_tag="VQ540_001068"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HET2544882.1"
                     /translation="MNQVINAMRKRVCDANQSLPKHGLVKFTWGNVSEVNRELGVIVI
                     KPSGVDYDELTPENMVVTDLDGKILEGDLRPSSDLPTHVQLYKAWSEIGSVVHTHSTE
                     AVAWAQAGRDIPFYGTTHADYFYGSIPCARSLTKDEVEVAYEKDTGLVIVEEFEHRGL
                     NPVEVPGIVVRNHGPFTWGKNPENAVYHSVVLEEVSKMNRFTEQINPRVGPAPQYILE
                     KHYQRKHGPNAYYGQK"
     gene            10498..12171
                     /locus_tag="VQ540_001069"
     CDS             10498..12171
                     /locus_tag="VQ540_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HET2544883.1"
                     /translation="MVLDKASCDLLQYLMDQETSKTIMAISKDLKESRRKIYYHIDKI
                     NAALGDEALHIISIPRIGIHLTEEQRDACCKLLSEVDSYDYIMSAHERMMIMLLWIGI
                     SKERITIEKLIELTEVSRNTVLNDLNSIRYQLTLEQYQVILQVSKSQGYHLHAHPLNK
                     IQYLQSLLYHIFMEENATFVSILEDKMKERLDDECLLSVEMNQFFKEQVPLVEQDLGK
                     KINHHEITFMLQVLPYLLLSCHNVEQYQERHQDIEKEFSLIRKRIEYQVSKKLGERLF
                     QKFEISLSGLEVSLVAVLLLSYRKDLDIHAESDDFRQLKLALEEFIWYFESQIRMEIE
                     NKDDLLRNLMIHCKALLFRKTYGIFSKNPLTKQIRSKYGELFLVTRKSAEILEGAWFI
                     RLTDDDIAYLTIHIGGFLKYTPSSQKNMKKVYLVCDEGVAVSRLLLKQCKLYFPNEQI
                     DTVFTTEQFKSVEDIAQVDVVITTNDDLDSRFPILRVNPILEAEDILKMLDYLKHNIF
                     RNKSKSFSENLSSLISSYIVDSKLASKFQEEVQTLINQEIVVQAFLEDI"
     gene            12283..13374
                     /gene="ulaG"
                     /locus_tag="VQ540_001070"
     CDS             12283..13374
                     /gene="ulaG"
                     /locus_tag="VQ540_001070"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HET2544884.1"
                     /translation="MPNVKEITRESWILATFPEWGTWLNEEIEEEVVPEGNFAMWWLG
                     NCGTWIKTPAGANVVMDLWSNRGKSTKKVKDMVRGHQMANMAGVRKLQPNLRVQPMVI
                     DPFAINELDYYLVSHFHSDHIDPYTAAAILNNPKLEHVKFIGPYHCGRIWEGWGVPKE
                     RIIVVKPGDTIELKDMKIHAVESFDRTCLVTLPVNGADETGGELAGLAVTDEEMAQKA
                     VNYIFETPGGTIYHGADSHFSNYFAKHGKDFKIDVALNNYGENPVGIQDKMTSIDLLR
                     MAENLRTKVIIPVHYDIWSNFMASTNEILELWKMRKDRLQYDFHPFIWEVGGKYTYPQ
                     DQHLVEYHHPRGFDDCFEQDSNIQFKALL"
     gene            13488..15464
                     /gene="tkt"
                     /locus_tag="VQ540_001071"
     CDS             13488..15464
                     /gene="tkt"
                     /locus_tag="VQ540_001071"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HET2544885.1"
                     /translation="MSNLSVNAIRFLGIDAINKANSGHPGVVMGAAPMAYSLFTKQLH
                     INPAQPNWINRDRFILSAGHGSMLLYALLHLSGFEDVSMDEIKSFRQWGSKTPGHPEF
                     GHTAGIDATTGPLGQGISTATGFAQAERFLAAKYNREGYNIFDHYTYVICGDGDLMEG
                     VSSEAASYAGLQKLDKLVVLYDSNDINLDGETKDSFTESVRDRYNAYGWHTALVENGT
                     DLEAIHAAIETAKASGKPSLIEVKTVIGYGSPNKQGTNAVHGAPLGADETASTRQALG
                     WDYEPFEIPEQVYADFKEHVADRGASAYQAWTKLVTDYKEAHPELAAEVEAIIDGRDP
                     VEVTPADFPALENGFSQATRNSSQDALNVVAAKLPTFLGGSADLAHSNMTYIKTDGLQ
                     DDANRLNRNIQFGVREFAMGTILNGMALHGGLRVYGGTFFVFSDYVKAAVRLSALQGL
                     PVTYVFTHDSIAVGEDGPTHEPVEHLAGLRAMPNLNVFRPADARETQAAWYLAVTSEK
                     TPTALVLTRQNLTVEDGTDFDKVAKGAYVVYENAADFDTILIATGSEVNLAVSAAKEL
                     ASQGEKIRVVSMPSTDVFDKQDAAYKEEILPNAVRRRVAVEMGASQNWYKYVGLDGAV
                     LGIDTFGASAPAPKVLAEYGFTVENLVKVVRNLK"
     gene            15581..15880
                     /gene="yajC"
                     /locus_tag="VQ540_001072"
     CDS             15581..15880
                     /gene="yajC"
                     /locus_tag="VQ540_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HET2544886.1"
                     /translation="MNPNITFLIMLVGMMALMFFMQRSQKKQAQKRMESLNKLQKGYE
                     VITIGGLYGTVDEVDTEKGTIVLDVEGVYLTFELAAIKTVLPLKETASLEGAIEK"
     gene            15927..16355
                     /locus_tag="VQ540_001073"
     CDS             15927..16355
                     /locus_tag="VQ540_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HET2544887.1"
                     /translation="MKKLVFVCLGNICRSPMAEFVMKSMTDNYEIQSRATSSWEHGNP
                     IHKGTQGIFQEYEIPYDKNKTSLQISKEDFEAFDYIIGMDASNISDLRQMCPVDCQDK
                     IYSFSSESVPDPWYTGDFEETYRRVQEGCQAWLERLEKES"
     gene            16357..16767
                     /locus_tag="VQ540_001074"
     CDS             16357..16767
                     /locus_tag="VQ540_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000427064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2544888.1"
                     /translation="MENLTNFYEKYRVYLTRPRLELLAVVTIVFCAVLVFFLNIPGKG
                     VLKLDNGTIVYDGSLVRGKMNGQGTITFQNGDQYTGGFNNGAFNGKGTFQSKEGWTYE
                     GDFVNGQAEGKGKLTTEQEVVYEGTFKQGVFQQK"
     gene            17067..19718
                     /gene="adhE"
                     /locus_tag="VQ540_001075"
                     /gene_synonym="adhC"
     CDS             17067..19718
                     /gene="adhE"
                     /locus_tag="VQ540_001075"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HET2544889.1"
                     /translation="MADKKTVTPEEKKLVAEKHVDELVQKALVALEEMRKLDQEQVDY
                     IVAKASVAALDAHGELALHAFEETGRGVFEDKATKNLFACEHVVNNMRHTKTVGVIEE
                     DDVTGLTLIAEPVGVVCGITPTTNPTSTAIFKSLISLKTRNPIVFAFHPSAQESSAHA
                     ARIVRDAAIAAGAPENCVQWITEPSMEATSALMNHEGIATILATGGNAMVKAAYSCGK
                     PALGVGAGNVPAYVEKSANIRQAAHDIVMSKSFDNGMVCASEQAVIIDKEIYDEFVAE
                     FKSYHTYFVNKKEKALLEEFCFGVKANSKNCAGAKLNADIVGKPATWIAEQAGFTVPE
                     GTNILAAECKEVGENEPLTREKLSPVIAVLKSESREDGITKARQMVEFNGLGHSAAIH
                     TADEELTKEFGKAVKAIRVICNSPSTFGGIGDVYNAFLPSLTLGCGSYGRNSVGDNVS
                     AINLLNIKKVGRRRNNMQWMKLPSKTYFERDSIQYLQKCRDVERVMIVTDHAMVELGF
                     LDRIIEQLDLRRNKVVYQIFADVEPDPDITTVNRGTEIMRAFKPDTIIALGGGSPMDA
                     AKVMWLFYEQPEVDFRDLVQKFMDIRKRAFKFPLLGKKTKFIAIPTTSGTGSEVTPFA
                     VISDKANNRKYPIADYSLTPTVAIVDPALVLTVPGFVAADTGMDVLTHATEAYVSQMA
                     SDYTDGLALQAIKLVFENLESSVKNADFHSREKMHNASTIAGMAFANAFLGISHSMAH
                     KIGAQFHTIHGRTNAILLPYVIRYNGTRPAKTATWPKYNYYRADEKYQDIARMLGLPA
                     STPEEGVESYAKAVYELGERIGIQMNFRDQGIDEKEWKEHSRELAFLAYEDQCSPANP
                     RLPMVDHMQEIIEDAYYGYKERPGRRK"
     gene            complement(20703..21011)
                     /locus_tag="VQ540_001076"
     CDS             complement(20703..21011)
                     /locus_tag="VQ540_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000134125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HET2544890.1"
                     /translation="MTEEMEYICFQLIANSGAAKSSFIEAIQLAKAGNLKEAKIKVEE
                     AEDSLVEAHKIHSNLIQKEATGEKIGFSLLFMHAEDQMASTEIIQLLSKEFIDLYQNK
                     "
     gene            complement(21008..21316)
                     /locus_tag="VQ540_001077"
     CDS             complement(21008..21316)
                     /locus_tag="VQ540_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET2544891.1"
                     /translation="MKQILLVCNAGMSTSMLVKKMQQSATERGIEISIQAKSMTEAKK
                     NIHEADVILIGPQIRYELLAVKEIAGNIPVDTIDMRDYGMMNGAKVLEQALAWIGEIR
                     "
     gene            complement(21321..22616)
                     /locus_tag="VQ540_001078"
     CDS             complement(21321..22616)
                     /locus_tag="VQ540_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000798148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HET2544892.1"
                     /translation="MKNSKFIDQFATFAGKLGNQIHLKTLRDAFVTVMPLYILAGLIV
                     LLNNTVFKWIFQGDTLTKFQYWGITIANGTLSISGMIIAVMVGYFLAKNRDFENPSAA
                     SMLSLVSLIVMMPNTVSVVPDGAKDAVNISGVLSFNNTGTGAMFAGVIVAIIATELFI
                     ELSNVKALQMNLGENIPPAVSRSFSVLLPVMTVISLFGIVSALLFNITGMNLISIITI
                     FIQEPIRHIGTSLIGVIIIYSLGNMLWLFGIHQAVIYSAILEPLLLINITENITAANN
                     GQAIPHIINLSQIQTFALMGGSGSTLCLLIATFLVSRNAVSKNVAKLSFGPGIFNINE
                     PVLFGYPIVYNISLAIPFITVPVLGILISYLATVTGFMSPAFIQVPWTTPVFLNAWLA
                     TAGDVRAVLVQFIIFALGVLLYIPFIKVNDKVVEQEMEG"
     gene            complement(22634..24043)
                     /locus_tag="VQ540_001079"
     CDS             complement(22634..24043)
                     /locus_tag="VQ540_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HET2544893.1"
                     /translation="MKKKLVFPNLFWWGAASSGPQTEGQYGKVHENVMDYWFKTHPED
                     FFDNVGPLVASNFFHTYTEDFHLMKEIGVNSFRTSIQWSRLIKNLETGEPDPKGIAFY
                     NAIIEEAKKNQMDLVMNLHHFDLPVELLQKYGGWESKHVVELFVKFAKTAFTCFGDKV
                     HYWTTFNEPMVIPEAGYLYAFHYPNLKGKGKEAVQVIYNLNLASAKVIQLYRSLGLDG
                     KIGIILNLTPAYPRSNSPEDLEASRFTEDFFNKVFLNPAVKGTFPERLVKQLERDGVL
                     WSHTEKELQLMKSNTVDFLGVNYYHPKRVQAQANPEEYQTPWMPDQYFKEYEWPERRM
                     NPYRGWEIFPKAIYDIAMIVKEEYGNIPWFISENGMGVENEARFIDENGVIDDVYRIE
                     FYEEHLRWLHKAIEEGSLCFGYHAWTAFDCWSWNNAYKNRYGFISVDLETQKRTIKSS
                     GRWYRKVSDNNGFEVEIEE"
     gene            24201..24929
                     /locus_tag="VQ540_001080"
     CDS             24201..24929
                     /locus_tag="VQ540_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HET2544894.1"
                     /translation="MSTKYLFIYNEIREKILCNKYTMNEQLPDEMTLAKQFACSRMTI
                     KKALDLLVSEGLIFRKRGQGTFVLSRGSSKRKLIVPERDIRGLTKISEDAHSTIDSRI
                     IHFKLEFANEFLAEKLQVALQSPVYNIYRLRIIDGKPYVLEQTYMSTDVIPGITEDIL
                     QKSIYNYIEGKLGLHIASATKILRASSSSENEQHYLQLLPTEPVFEVEQVAYLDNGTP
                     FEYSISRHRYDLFEFNSFALRHSS"
     gene            25389..25583
                     /locus_tag="VQ540_001081"
     CDS             25389..25583
                     /locus_tag="VQ540_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET2544895.1"
                     /translation="MKGKEYENRTVSFAISSKGEKMKVENISYRVDHRILFDNISFDT
                     SSSDVTLITGKNGTGKSTLL"
     gene            complement(25949..27259)
                     /locus_tag="VQ540_001082"
     CDS             complement(25949..27259)
                     /locus_tag="VQ540_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HET2544896.1"
                     /translation="MIHLIMISAIALAIGIGYRTKINIGLLAIAFSYLIATTLMGLSP
                     KELLHFWPTSLFFTIFSVSLFYNFAITNGTLDVLAQHILYRTRTYPNALYMILYLMAT
                     LLSALGAGFFTTMAVCCPLAITLCQKADKHPLIGAQAVNWGASGGANLITSSSGIVFQ
                     GLFKQMGWEEQAFSLGNHIFIVSIIYPLIVLLLLSCYSHYSKGRTNSSLTIDQPPLLS
                     KVQRQTTLLMISSMVLVWLFPLLHLIFPNIAWIATYRKTFDIGFVSILMVCLALRLKL
                     GKQEAILAKVPWATIIMLCGMSLLMSLAVKSGLVTLIGHLMTTSIPHFWLPLFFCVIA
                     GVMSLFSSTLSVVAPALFPIIAIISAQNPQIDIHLLTTATVIGALSTNISPFSSAGSL
                     IQLSLPNIEERGLAFKKQIILGVPISLSLGLLTTWILILLASLS"
     gene            27496..28368
                     /locus_tag="VQ540_001083"
     CDS             27496..28368
                     /locus_tag="VQ540_001083"
                     /EC_number="2.4.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylating nicotinate-nucleotide
                     diphosphorylase"
                     /protein_id="HET2544897.1"
                     /translation="MSIISTDLTPFQIDDTLKAALREDVHSEDYSTNAIFDHHGQAKV
                     SLFAKEAGVLAGLTVFQRVFTLFDAEVTFQNPHQFKDGDRLTSGDLVLEIIGSVRSLL
                     TCERVALNFLQHLSGIASMTAAYVEALGDDCIKVFDTRKTTPNLRLFEKYAVRVGGGY
                     NHRFNLSDAILLKDNHIAAVGSVQKAIAQARAYAPFVKMVEVEVESLAAAEEAAAAGA
                     DIIMLDNMSLEQIEQAITLIAGRSRIECSGNIDMTTISRFRGLAIDYVSSGSLTHSAK
                     SLDFSMKGLTYLDV"
BASE COUNT         8920 a         5065 c         5928 g         8536 t
ORIGIN      
        1 aaaagtcgtg cgctgaacac caacaagacg cttaaattgt gcattggtta gttgtttact
       61 ttcttcataa attttattgt atcatatttt tgtttcacag gaagtctaat aaataaaaat
      121 tctttaaaat tttgttggga aaatgggaaa agatataaat ggaaacttag tataacactt
      181 ggaaaactct gtaaaaatag taagtcaatt catgtcccgt tttttctcta gggaagttgg
      241 gcggctatat ttatatgacc atttgtcgta ataaacatcc ctaccaaggg tcaatagaaa
      301 taaattcaac gaaacttttg ctgtcagatt tagatgccca atttgtcatt tatactcttt
      361 catataggac tttctataag gatggaaaaa agaagggaaa tttgataaga taggaatatg
      421 gattttgaaa aaattgaaca agcttatacc tatttactag agaatgtcca agtcatccaa
      481 agtgatttgg cgaccaactt ttatgacgcc ttggtggagc aaaacagcat ctatctggat
      541 ggtgaaactg agctaaacca ggtcaaagac aacaatcagg cccttaagcg tttagcacta
      601 cgcaaagaag aatggctcaa gacctaccag tttctcttga tgaaggctgg gcaaacagaa
      661 cccttgcagg ccaatcacca gtttacaccg gatgctattg ctttgctttt ggtgtttatt
      721 gtggaagagt tgtttaaaga ggaggaaatt actatcctcg aaatgggttc tgggatggga
      781 attctaggcg ctactttctt gatctcgctt gataaaaagg tggattactt gggaatggaa
      841 gtggatgatt tgctgattga tctggcagct agcatggcag atgtaattgg tttgcaggct
      901 ggctttgtcc aaggagatgc cgttcgtcca caaatgctca aagaaagcga tgtggtcatc
      961 agtgacttgc ctgttggcta ttatcctgat gatgccgttg cgtcgcgcca tcaagttgct
     1021 tctagccaag aacatactta cgcccatcac ttgctcatgg aacaagggct taagtacctc
     1081 aagtcagacg gatacgctat ttttctagct ccgagtgatt tgttgaccag tcctcaaagt
     1141 gatttgttaa aagaatggct gaaagaagag gcgagtctgg ttgctatgat tagtctgcct
     1201 gaaaatctct ttgctaatgc taaacaatct aagactattt ttatcctaca gaagaaaagt
     1261 gaaatagcag tggagccttt tgtttatcca cttgctagct tgcaagatgc aagtgtttta
     1321 atgaaattta aagaaaattt tcaaaaatgg actcaaggta ctgaaatata aaatagattt
     1381 tgttataata gttgaaaacg cttaaaaagg ggtatcatgt tatgacaaaa acaattgcaa
     1441 tcaatgcagg aagttcaagt ttgaaatggc aattatactt aatgccagag gaaaaagtgt
     1501 tagccaaagg tttgattgaa cgtatcggtt tgaaagattc aatttcaact gtaaaatttg
     1561 acggccgttc tgaacaacaa attttggata tcgaaaatca tacacaagct gttaaaattt
     1621 tattggatga cttgattcgt ttcgatatta tcaaggctta tgacgagatt acaggtgttg
     1681 gccaccgtgt tgtagcaggt ggagaatatt tcaaagaatc aacagttgtt gagggagatg
     1741 ttttagaaaa agttgaagag ttgagtttgt tggctcctct acacaacccg gccaatgcag
     1801 caggtgttcg tgctttcaag gaattgttgc cagacattac cagtgtagtt gtttttgata
     1861 cttccttcca cacaagtatg ccagagaaag cttatcgcta ccctctacca acaaaatatt
     1921 acacagaaaa caaggttcgt aaatacggtg ctcatggtac aagtcaccag tttgtagcag
     1981 gagaagctgc aaaactcttg ggacgtccat tagaagactt gaagttaatt acctgtcata
     2041 ttggtaacgg aggctcaatt acagctgtga aagccggcaa atctgtagac acttctatgg
     2101 ggttcactcc tcttggtggt attatgatgg gaacgcgtac aggggatatt gatccagcta
     2161 tcattcctta tttaatgcaa tatacagagg attttaacac accagaagat atcagtcgtg
     2221 ttcttaaccg tgaatcaggt cttttgggag tttctgctaa ttctagcgat atgcgcgata
     2281 tagaagcagc tgtagcagaa gggaatcacg aggctagctt ggcttatgaa atgtatgttg
     2341 accgtatcca aaaacatatc ggtcagtacc ttgcagtgct aaatggaaca gatgccattg
     2401 ttttcacagc aggtgtcggt gaaaatgcag agaatttccg tcgtgatgta atctcaggga
     2461 tttcgtggtt tggttgtgat gttgatgatg aaaagaatgt ctttggcgtt acaggagaca
     2521 tctcaacaga ggcagctaaa atccgtgtct tggttattcc aacagatgaa gaattagtca
     2581 ttgcccgtga cgttgaacgc ttgaaaaaat aagtgaaact aaaaaaatat tcaatacaag
     2641 gagttgggaa agttattttt ccagcttctt tttctgatga aattgtccaa aaccttgcta
     2701 tgattggctt ttttgaaaaa tatggtataa tagtagtaat ttaatagatg gagttgagtt
     2761 ttgaagaaaa actttcgtgt aaaaagagag aaagatttta aggcgatttt caaggagggg
     2821 acaagttttg ctaatcgcaa atttgtggtc taccaattag aaaaccagaa aaaccatttt
     2881 cgagtaggtc tatcagttag caaaaaactg gggaatgccg tcactagaaa tcaaattaag
     2941 cgacggattc ggcatattat ccagaatgca aaagggagtc tggtagaaga tgtcgacttt
     3001 gttgtcattg ctcgaaaagg agtcgaaacc ttgggatacg cagagatgga gaaaaatcta
     3061 ctccatgtat taaaattatc aaagatttac cgggaaggaa atgggagtga aaaagaaact
     3121 aaagttgact agtttgctag gactgtctct gttaatcatg acagcctgtg cgactaatgg
     3181 ggtaactagc gatattacag ccgaatcggc tgatttttgg agtaaattgg tttacttctt
     3241 tgcgaaaatc attcgctttt tatcgtttga tattagtatc ggagtgggga ttattctctt
     3301 tacggtcttg attcgtacag tcctcttgcc agtctttcag gtgcaaatgg tggcttctag
     3361 gaaaatgcag gaagctcagc cacgcattaa ggcgcttcga gaacaatatc caggtcgaga
     3421 tatggaaagc agaaccaaac tagagcagga aatgcgtaaa gtatttaaag aaatgggtgt
     3481 cagacagtca gattctcttt ggccgatttt gattcagatg ccggttattt tggccttgtt
     3541 ccaagcccta tcaagagttg actttttaaa gacaggtcat ttcttatgga ttaaccttgg
     3601 tagtgtggat acaacccttg ttcttccgat tttagcagca gtattcacct ttttaagtac
     3661 ttggttgtcc aacaaagctt tgtctgagcg aaatggcgct acgactgcga tgatgtatgg
     3721 gattccagtc ttgattttta tctttgcagt ttatgcgcca ggtggagtcg ccctatactg
     3781 gacagtgtct aatgcttatc aagtcttgca aacctatttc ttgaataatc cattcaagat
     3841 tatcgcagag cgcgaggccg tagtacaggc acaaaaagat ttggaaaata gaaaaagaaa
     3901 agccaagaaa aaggctcaga aaacgaaata aataaggagg aatctggtaa tggtagtatt
     3961 tacaggttca actgttgaag aagcaatcca gaaaggattg aaagaattag atattccaag
     4021 aatgaaggct catatcaaag tcatttctag ggagaaaaaa ggctttcttg gtctatttgg
     4081 taaaaaacca gcccaagtgg atattgaagc gattagtgaa acgactgttg tcaaagcaaa
     4141 tcaacaggta gtaaaaggcg ttccgaaaaa aatcaatgat ttgaacgagc ctgtgaagac
     4201 ggttagtgaa gaaaccgttg accttggtca tgtggttgat gctattaaaa aaatagagga
     4261 agaaggtcaa ggtatttctg atgaagtcaa ggctgaaatc ttaaaacatg aaagacatgc
     4321 cagcactatc ttagaagaaa ctggtcacat tgagatttta aatgaacttc aaatcgagga
     4381 agcgatgagg gaagaagcag gcgctgatga ccttgaaact gagcaagatc aaactgaaaa
     4441 tcaagacttg aaagagatgg gcttgaaggt cgagcaaagt tatgatattg cccaggtggc
     4501 tacggatgtg actgcctatg ttcaagcgat tgtggatgac atggatgttg aagctacact
     4561 ttcaaatgat tataaccgtc gtagcatcaa tctacaaatt gacaccaacg aaccaggtcg
     4621 tattatcggc taccatggta aagtcttgaa ggccttgcaa ctgttggctc aaaattatct
     4681 ttacaaccgc tattccaaaa ccttctacgt tacaatcaat gtcaatgatt atgtcgaaca
     4741 ccgtgcagaa gtcttgcaga cctatgcgca aaaattggcg attcgtgttt tagaagaagg
     4801 acgtagtcat caaacagatc caatgtcgaa tagtgaacgc aagattatcc accgtattat
     4861 ttcacgtatg gatggcgtga ccagttactc tgaaggtgat gagccaaatc gctatgtcgt
     4921 tgtagataca gaataagtaa aatcagggtt gacctgattt tttgctagct agaggaggtt
     4981 aaactaatgt tgaataagat aagagactat ttagactttg ctggtttgca gtaccgtaat
     5041 cctgataaag cgggagcaga gcgagagaag atgctggcat tccgccacaa aggacaagag
     5101 gcccgaaagg cttttacaga actggccaaa gcctttcaag caagccatcc aggatggcaa
     5161 ctccaacaga ctagtcagtg gatgaatcag gcccagcgtt tgagaccaca tttttgggtt
     5221 tatctacaga gagacgaaca agtgacagaa cctatgatgg ccttacgttt gtatgggaca
     5281 tctactgact ttggaatttc tttggaagtc agtttcatcg aacgtaagaa ggatgagcaa
     5341 acactgggca agcaggccaa agttttagac attccaaccg ttaaagggat ttattatcta
     5401 acctactcta atggtcaaag tcaacggtgg gaggcgaatg aagaaaagcg tcgtacttta
     5461 cgcgagaagg tgagaagtca agaagttcga aaagttttag tgaaggtaga tgttcctatg
     5521 acagaaaatt cgtctgaaga agaaatcgta gaaggcttat tgaagtctta ttctaaaatt
     5581 cttccctatt atctagctac gagaaaataa gataatttgt aaaacatcat aaatcataca
     5641 gtccaagagt gaacagtccg ctgtgtaatt cttggtcttt ttgtttgcgc tttcgcatta
     5701 tataataaac ttacaaaaac aattcaaaag gagaacaatt atggaagtcg tttcaagtgt
     5761 tctaaattgg ttttctagca atattttgca gaatcccgca tttttcgtag gtttattggt
     5821 gttgatagga tatgcacttt tgaaaaaacc tgcccatgac gttttttcag ggtttgttaa
     5881 agcaacagta gggtatatgt tgcttaacgt gggtgctggt ggtttggtta caacctttcg
     5941 tccaatctta gcagctctta actacaaatt ccaaattggt gcagcggtta tcgaccctta
     6001 ctttggactt gctgcagcaa acaacaaaat tgcagcagag tttccagatt ttgttggaac
     6061 tgcaactaca gctctattga ttggttttgg aataaatatc ttgctcgtag ctcttcgaaa
     6121 gattacgaag gtaagaaccc tctttattac tggtcacatc atggtacaac aagctgcaac
     6181 agtatctctt atggttctat tcttagtacc acaattgcgc aatgcttacg gtacagcagc
     6241 gattggtatc atctgtggac tttactgggc agttagttca aatatgactg ttgaggcaac
     6301 tcaacgcttg actggtggtg gcggatttgc gattggtcac caacagcaat ttgcaatctg
     6361 gtttgtagat aaagtagcag gacgctttgg taagaaagaa gaaagtttag acaatcttaa
     6421 attacctaag ttcctctcaa tcttccacga tacagttgtt gcatctgcta ccttgatgct
     6481 cgtattcttc ggagccattc ttttaatctt gggtccagac attatgtcta ataaagaagt
     6541 catcacttca ggaactctat tcaatcctgc taaacaagat ttctttatgt acattatcca
     6601 aacagccttt accttctcag tttacttgtt cgttttgatg caaggtgtcc gaatgttcgt
     6661 atctgagttg acaaacgcct tccaaggtat ttcaaacaaa ttgttgccag gttcattccc
     6721 agcggttgac gttgcagctt cttatggatt tggttctcca aatgctgtct tgtcaggatt
     6781 tacctttggt ttgattggtc aattgattac aattgttttg ctcatcgtct ttaaaaatcc
     6841 gattcttatt attacaggat ttgtaccagt gttctttgac aatgcagcca ttgcggtcta
     6901 cgctgataaa cgcggcggat ggaaagcggc tgttatcctt tcctttatat caggtgtcct
     6961 tcaagttgct ctaggagctc tttgtgtggc ccttctcgat ttggcatctt atggtggcta
     7021 ccatggaaat atcgactttg aattcccatg gcttggattt ggatatatct tcaaatacct
     7081 tggtattgtt ggttatgtac ttgtgtgtct cttcttgctt gttattcctc aacttcaatt
     7141 tgccaaagca aaagataaag agaaatatta caacggtgaa gttcaagaag aagcttagta
     7201 tctagaaaag gagaaataaa atggttaaag tattagcagc gtgcggaaat ggaatgggtt
     7261 catcaatggt tatcaagatg aaggttgaaa atgctctccg taagcttaat caaacagatt
     7321 ttacagtcaa ttcatgcagt gtcggtgaag ctaaaggttt agcagtagga tatgacattg
     7381 taatcgcttc tcttcatttg attcaagaat tggaagggcg aactaatggg aagttaattg
     7441 ggcttgataa cttgatggat gataaagaaa tcaccgaaaa actcagtcaa gcactacagt
     7501 aaaaggttgg agggggctgg acagaaactg agagttatcg tttctgtcca gccccctctt
     7561 taaataaagg aggcagatat gaatttaaaa caagctttaa ttgacaatga ctcgatccga
     7621 ctaggtttag aggctaacaa ttggaaagaa gcagtcaagg tagcagtaga tcccttgatt
     7681 gaaagtgggg caattttgcc agagtattac gatgctatca ttgaatcgac tgaagagtat
     7741 gggccttact atatcttgat gccaggtatg gctatgcccc acgctagacc tgaagctggt
     7801 gtgcaaagtg atgccttttc attgattacc ttacaaaatc ctgttgtatt ttcagatggg
     7861 aaagaggtat ctgttttgtt ggcactagca gcaacaagtt caaaaattca cacaagtgta
     7921 gccattccac aaattattgc cctgtttgaa ttagaagatt ctattgcacg tttacaggct
     7981 tgccagacta aagaagatgt cttggctatg attgaagaat ctaaggatag cccttatctc
     8041 gaaggattgg atttggaaag ttagaaagag gaataaagaa atgacaaaaa gaatacctaa
     8101 tttacaagtt gcattagacc attcagactt gcaaggagcg attaaagcag ctgtttctgt
     8161 tggtcaggaa gtagatatta tcgaagctgg aactgtttgc ttgcttcaag ttggaagtga
     8221 actggctgaa gtcttgcgta gccttttccc agataagatt attgtggcag acacaaaatg
     8281 tgctgatgct ggtggaacag ttgctaaaaa taatgcggtt cgtggagcag actggatgac
     8341 ttgtatctgt tgtgcaacca tccctactat ggaagcagct ctaaaggcta tcaagactga
     8401 acgaggagaa cgaggcgaaa tccagatcga gctttatggc gattggactt ttgaacaagc
     8461 tcagctttgg ctagatgcag gtatctcaca agctatttat caccaatctc gtgatgctct
     8521 tcttgctggt gaaacttggg gtgaaaaaga ccttaataag gttaaaaaac tcattgacat
     8581 gggcttccgt gtatctgtaa caggtggtct agatgtagat actctcaaac tctttgaagg
     8641 tgttgatgtc tttaccttta tcgcaggtcg tggaattaca gaggctgcgg atccagcagg
     8701 agcagcgcgt gccttcaagg atgaaatcaa acgaatttgg gggtaaatca tggtacgtcc
     8761 aattggaatt tatgaaaagg caaccccaac acactttact tggctagaac gtttaaattt
     8821 tgccaaggag ttaggctttg attttgtcga gatgtctatt gacgaacgtg acgagcgttt
     8881 agcaagactt gactggagta aggaagaacg cttggaagtt gtcaaagaaa tctatgaaac
     8941 tggtgttcgt attccttcta tctgtttttc aggccatcgt cgctacccat tgggttcaaa
     9001 agatccagtt ctagaggaaa aatctctaga actcatgaaa aaatgtatcg aattagctca
     9061 agacttggga gttcgtacga ttcaattagc tggttacgat gtttactatg aggaaaagtc
     9121 accccagaca cgccaacgtt ttatcaaaaa tttgagaaaa gcctgtgact gggctgaaga
     9181 agctcaggtg gtacttgcta ttgaaattat ggatgatcct ttcatcaata gcatcgaaaa
     9241 atatttggct atagaaaaag agattgactc tcccttcctc tttgtatatc cagatattgg
     9301 taatgtgtct gcatggcata atgatatcta tagtgagttt tatcttggtc atcatgccat
     9361 cgcagctctc catctcaagg atacttatgc agtgacagaa agttcaaggg gccagttccg
     9421 agatgtacct tttgggcaag gttgtgtcaa atgggaagaa gctttcgata ttttaaagga
     9481 aaccaattat aatggacctt tcctaatcga aatgtggtct gaaaattgtg aaacagtaga
     9541 agaaacacgc gcagccattc aagaggcgca agcttttctc tatccactca ttaagaaagc
     9601 aggtttgatg taagatgaat caagtaatca atgctatgcg taaacgagtc tgtgatgcca
     9661 atcaatcatt gccaaaacat ggacttgtca aatttacctg ggggaatgta tctgaagtca
     9721 atcgcgaact cggtgtcatt gttatcaaac catcaggcgt ggattatgac gaattgacac
     9781 ctgaaaacat ggtagtgact gatctagatg gtaagatcct agaaggggat ttaagaccat
     9841 cttccgacct cccaactcat gtgcaattat ataaggcttg gtcagaaatt ggtagtgtgg
     9901 ttcacaccca ttcgacagaa gctgttgctt gggctcaggc aggtcgtgat attcctttct
     9961 acggaacaac ccatgcagat tatttctacg gttcaatccc ttgcgcccgt agtttgacca
    10021 aggacgaagt agaagtggcc tatgaaaaag atactggcct ggttatcgta gaagagtttg
    10081 aacatcgcgg acttaacccg gttgaagtac caggaattgt tgtacgcaat cacggtccat
    10141 tcacctgggg caaaaatcca gagaatgctg tttatcactc tgtcgtacta gaggaagtat
    10201 caaagatgaa tcgctttaca gaacaaatca atccaagagt tggacctgct ccccagtaca
    10261 tactagaaaa acactaccaa cgtaaacatg gaccaaatgc ttattatggt caaaagtaag
    10321 aacgatgaag gaggagaaaa agataaattt agctcctctt tttacatttg atttttattg
    10381 agagtaaagt tggagttgaa gtaattttaa aagatttttt agaaatagcg cttgatatat
    10441 atatggtaaa ataaaaagaa ttgctgtgat atcaatagat ttgggggatt ttttaatatg
    10501 gtactggata aggcaagttg tgatttgctt caatatttga tggatcaaga aacgtccaaa
    10561 acgattatgg cgatttcgaa agatttgaaa gagtcaagaa ggaaaattta ttatcacatt
    10621 gacaaaatca atgctgctct gggtgacgag gcgcttcaca tcattagtat tccacgaatt
    10681 ggtattcact taacggaaga gcagagagat gcttgttgta aactattatc ggaagtagat
    10741 tcgtacgatt atatcatgag tgcgcatgaa cgtatgatga taatgttact atggataggt
    10801 atttctaaag aacgtattac gattgaaaaa ttgatagagt taacagaggt atctaggaat
    10861 actgttctca atgatttgaa tagtattcgt tatcaactaa ctttggaaca atatcaggtg
    10921 atcttgcaag tgagcaagtc acagggatac caccttcatg cccaccctct taataaaatt
    10981 cagtatcttc aatcgcttct atatcatatt tttatggaag aaaatgccac ttttgtatct
    11041 attttagaag ataagatgaa agagaggtta gatgatgagt gtttgctttc tgttgaaatg
    11101 aaccaatttt ttaaggaaca ggttccttta gttgaacaag atttagggaa gaaaataaac
    11161 catcatgaaa taacttttat gttgcaggtt ctaccttatt tgctgttaag ctgtcataat
    11221 gttgaacagt atcaagaaag acatcaggat atagagaaag aattttcttt gataagaaaa
    11281 agaatagagt atcaggtgtc taagaaatta ggagaacggt tgtttcaaaa gtttgaaatt
    11341 tctttgtcag gacttgaagt ttctcttgta gctgttctcc tcctctccta tcgtaaagat
    11401 ttggatattc atgcagaaag tgatgatttt cggcaattaa aacttgcttt agaagaattt
    11461 atctggtatt ttgaatcaca aatccgaatg gagattgaga acaaggatga tttgttacga
    11521 aatttgatga tccactgtaa agccttgtta tttagaaaga cttacggtat tttttctaaa
    11581 aatcctctaa caaaacaaat tcgatccaag tatggagaat tatttttagt cactagaaaa
    11641 tctgcggaaa ttttagaagg agcatggttt attcggctaa cagacgatga tattgcctat
    11701 ttgacgattc atattggagg atttttaaaa tatacaccat catctcaaaa aaatatgaaa
    11761 aaagtttatc tcgtttgtga tgaaggtgtt gcggtttcga gacttttgct gaaacaatgc
    11821 aaactttatt ttccaaatga gcaaattgac actgtattta caacagaaca atttaagagt
    11881 gtggaagata ttgcacaagt tgatgtagtg attactacta atgatgattt ggatagcaga
    11941 tttccgattt taagggttaa tcctatcctt gaagcagaag atattttgaa aatgctagac
    12001 tatcttaaac acaatatatt tcgtaataag agcaaaagtt tcagtgaaaa tctttctagt
    12061 cttatttcgt cttatattgt agacagcaag ttggctagta agttccaaga agaggttcaa
    12121 acacttataa atcaagaaat agtagttcaa gcttttttgg aagatatttg aaggacagtc
    12181 caatgatgaa cacaaacctg tgtttttctt ggtctttttt agtgttttga agggtggtat
    12241 actaatctca aagataacaa ttatatccaa aggaggcaac atatgccaaa cgtcaaagaa
    12301 attacaagag agtcatggat tttagccact ttcccagagt ggggaacatg gttgaacgaa
    12361 gaaatcgaag aagaagtcgt acctgaaggc aactttgcca tgtggtggct aggcaactgt
    12421 ggtacttgga ttaagacacc agctggtgct aacgttgtca tggacctttg gtcaaaccgt
    12481 ggaaaatcaa ccaaaaaagt gaaagatatg gttcgtgggc accaaatggc aaatatggca
    12541 ggtgttcgta agctgcaacc aaacttgcgt gttcagccaa tggttatcga tccatttgct
    12601 atcaacgaac tagactatta cttagtttca cacttccaca gtgatcatat cgacccatac
    12661 acagctgcag caattctcaa taatcctaag ttagagcatg ttaagtttat cggtccttac
    12721 cactgtggac gaatctggga aggatggggt gttccaaaag aacgtatcat cgttgttaaa
    12781 ccaggtgaca ctatcgaatt aaaagatatg aagattcatg cagtagaatc atttgaccgt
    12841 acttgcttgg taactctccc agtgaacggt gctgatgaga caggcggtga acttgctggc
    12901 ttggctgtta cagatgaaga aatggctcaa aaggctgtta actatatctt tgaaacacca
    12961 ggtggaacca tctatcatgg tgcagattct cacttctcaa actattttgc aaaacatggt
    13021 aaagacttta aaattgatgt tgctttgaat aactatggtg aaaatccggt aggtatccaa
    13081 gacaaaatga catctatcga ccttcttcgt atggcagaaa atctgcgtac caaagtcatt
    13141 atcccagttc actatgatat ctggtctaac ttcatggctt ctactaatga gattctagaa
    13201 ctttggaaaa tgcgaaaaga tcgcttgcaa tacgatttcc atccatttat ctgggaagtt
    13261 ggcggtaagt acacttatcc tcaagatcaa cacttagtag aataccatca tccacgtggt
    13321 tttgatgatt gttttgaaca agactctaac attcaattta aagctttgct ataatataaa
    13381 aatattcttt ggaggttatc cgtatgttgc atgatacgga taattttcat ataatagtaa
    13441 aatagaatgt gtgattcaat aatcacctca aatagaaagg aaattctatg tcaaatctat
    13501 ctgttaatgc aattcgtttt ctaggtattg acgccattaa taaagccaac tcaggtcatc
    13561 caggtgtggt tatgggagcg gctccgatgg cttacagcct ctttacaaaa caacttcata
    13621 tcaatccagc tcaaccaaac tggattaacc gcgaccgctt tattctttca gcaggtcatg
    13681 gttcaatgct cctttatgct cttcttcacc tttctggttt tgaagatgtc agcatggatg
    13741 agattaagag tttccgtcaa tggggttcaa aaacaccagg tcacccagaa tttggtcata
    13801 cggcagggat tgatgctacg acaggtcctc tagggcaagg gatttcaact gctactggtt
    13861 ttgcccaagc agaacgtttc ttggcagcca aatataaccg tgaaggttac aatatctttg
    13921 accactatac ttacgttatc tgtggagacg gagacttgat ggaaggtgtc tcaagcgagg
    13981 cagcttcata cgcaggcttg caaaaacttg ataagttggt tgttctttat gattcaaatg
    14041 atatcaactt ggatggtgag acaaaggatt cctttacaga aagtgttcgt gaccgttaca
    14101 atgcctacgg ttggcatact gccttggttg aaaatggaac agacttggaa gccatccatg
    14161 ctgctatcga aacagcaaaa gcttcaggca agccatcttt gattgaagtg aagacggtta
    14221 ttggatacgg ttctccaaac aaacaaggaa ctaatgctgt acacggcgcc cctcttggag
    14281 cagatgaaac tgcatcaact cgtcaagccc tcggttggga ctacgaacca tttgaaattc
    14341 cagaacaagt atatgctgat ttcaaagaac atgttgcaga ccgtggcgca tcagcttatc
    14401 aagcttggac taaattagtt acagattata aagaagctca tccagaactg gctgcagaag
    14461 tagaagccat catcgacgga cgtgatccag tcgaagtgac tccagcagac ttcccagctt
    14521 tagaaaatgg tttttctcaa gcaactcgta attcaagtca agatgccttg aatgttgtgg
    14581 cagctaaatt accaaccttt ctaggtggat cagctgacct tgctcactca aacatgactt
    14641 atatcaagac ggatggactt caagacgatg ccaatcgctt gaatcgtaac attcagtttg
    14701 gtgttcgtga atttgcaatg ggaacaatct tgaacgggat ggcccttcat ggtggacttc
    14761 gtgtatacgg tggaactttc ttcgtcttct ctgactatgt gaaggcagct gtccgcttgt
    14821 cagccttaca aggacttcct gtgacttatg tctttaccca tgattcaatc gcagttgggg
    14881 aagatggtcc gactcatgaa ccagttgagc atttagcagg tcttcgtgct atgccaaatc
    14941 taaatgtttt ccgtccagca gatgcgcgtg aaacgcaagc agcttggtac cttgcagtga
    15001 caagtgagaa aacaccaact gcccttgtct tgacacgtca aaatttgact gttgaagatg
    15061 gaacagactt cgacaaggtt gctaaaggtg cttatgttgt atatgaaaat gcagccgact
    15121 ttgataccat cttgattgcg acaggttcag aggttaatct tgctgtctca gctgctaaag
    15181 aattggctag tcaaggcgaa aaaatccgcg tagtcagcat gccatctaca gatgtctttg
    15241 ataaacaaga tgcagcttac aaggaagaaa ttcttccaaa tgcagtccgc cgtcgtgttg
    15301 cagtcgaaat gggtgcaagt caaaactggt acaaatatgt tggtctcgat ggtgccgttc
    15361 taggtattga taccttcgga gcctctgccc cagcaccaaa agtattggca gaatatggct
    15421 ttactgtaga aaatcttgta aaagttgttc gaaacttgaa ataatcctaa aaatcagggc
    15481 gtaagctctg gtttttctta ccagaaaagt aaggtacaat cttgtaaaag tagctgaaat
    15541 ttgatatagt agtcctatgt aaaagacaaa ggagaaaaca atgaatccaa atattacttt
    15601 tttaatcatg cttgtaggta tgatggcctt gatgttcttt atgcaacgtt ctcaaaagaa
    15661 acaagctcaa aagcgtatgg aaagcttaaa taaactacaa aaaggctatg aagtgattac
    15721 aatcggtgga ctttatggaa cagtcgatga agtagatacg gagaagggaa caatagttct
    15781 tgacgtagag ggagtttact tgacttttga actagctgct atcaagacag tattaccgct
    15841 gaaagaaaca gcttcactag aaggcgcaat tgaaaaataa gacgggatca cgaactcccg
    15901 tttttctata aaagaaagga aatgggatga aaaaattagt ctttgtctgt ctgggaaata
    15961 tttgccgtag ccctatggcc gagtttgtta tgaaatcaat gacagataac tacgaaatcc
    16021 aaagtcgagc aacttcctct tgggaacatg gcaatccgat tcataagggg actcagggaa
    16081 tttttcaaga gtatgagatt ccttatgaca agaacaagac atcgcttcag attagtaagg
    16141 aagattttga agcctttgat tatattatcg gaatggacgc ttcaaatatt tctgacttac
    16201 gtcagatgtg tccagtagac tgtcaagata agatttactc attttcatct gaaagtgttc
    16261 cagacccttg gtatacagga gattttgaag aaacctatcg acgtgttcaa gagggctgtc
    16321 aagcttggtt agaacgttta gaaaaggaga gttaaggtgg aaaatcttac gaatttttac
    16381 gaaaagtatc gtgtctatct gactcgtcca cgtttagagc ttttggcagt agttaccatt
    16441 gttttctgtg ctgtactcgt cttttttcta aatattccag gaaaaggtgt cttaaaactc
    16501 gataatggaa cgattgttta tgatggcagt cttgtccgcg gtaaaatgaa tggccaaggt
    16561 accattacct tccaaaatgg agaccaatat acaggtggct tcaacaatgg agccttcaac
    16621 ggaaaaggta cctttcaatc taaagaaggc tggacctacg aaggtgattt tgtaaatggt
    16681 caggctgaag gaaaagggaa actaacaaca gaacaagaag tcgtttatga aggaactttt
    16741 aaacaaggcg tttttcaaca aaaataaagc ctccttatca aaggaggtat tattagaatc
    16801 gcaaggtaag cgcttacctg caaatccctt tctttccaaa tccctcttcc aagcaagttt
    16861 gtgaaataaa aaatatttga aataaatttc acaaacttca aagataaaac ctgataagaa
    16921 aagaaaatga gaaaagtttc acaagagttt aaaaattctt tgtgaaatgt ttatgaaact
    16981 gtttacaaag ttgaaataat gcgttataat aaacttgtga aaaaattaac aaaggatatc
    17041 gttccttgaa agctatggag gaaaatatgg ctgataaaaa aactgtgaca ccagaggaaa
    17101 agaaactcgt tgctgaaaaa cacgtagatg agttggttca aaaagctcta gttgcccttg
    17161 aagaaatgcg taaattggat caagaacaag ttgactacat cgttgccaaa gcatcagtag
    17221 cagctttgga tgcccacgga gaattggctt tacatgcctt tgaagaaaca ggacgtggtg
    17281 tatttgaaga taaagcaact aagaacttgt ttgcttgtga acacgtggta aacaacatgc
    17341 gtcacactaa aacagttggc gttatcgaag aagatgatgt aacaggattg accctgattg
    17401 ctgaaccagt tggtgttgtt tgtggtatca ctccaacaac aaacccaaca tcaacagcga
    17461 tcttcaaatc attgatttca ttgaagacac gtaatccaat cgtctttgcc ttccatccat
    17521 cagctcaaga atcatcagct catgcagctc gtatcgtccg cgatgcagct atcgcagctg
    17581 gtgctcctga aaactgtgta cagtggatca ctgaaccatc tatggaagca actagtgccc
    17641 ttatgaacca cgaaggtatt gcaacaatcc ttgcaacagg tggtaatgcc atggttaaag
    17701 ccgcatactc atgtggtaaa ccagctcttg gggtaggtgc cggaaacgtt ccagcttatg
    17761 ttgaaaaatc agcaaacatt cgtcaagcag cacacgatat cgtcatgtct aaatcatttg
    17821 ataacggtat ggtctgtgca tctgaacaag cagttatcat tgataaagaa atttacgatg
    17881 aatttgtagc agagttcaaa tcttaccaca cttactttgt aaacaaaaaa gaaaaagctc
    17941 ttcttgaaga gttctgcttc ggcgtcaaag caaacagcaa aaactgtgct ggtgcaaaat
    18001 tgaacgctga catcgttggt aaaccagcaa cttggattgc agaacaagca ggatttacag
    18061 ttccagaagg aacaaacatt cttgctgcag aatgtaaaga agttggcgaa aatgagccat
    18121 tgactcgtga aaaattgtca ccagttattg cagttttgaa atctgaaagc cgtgaagatg
    18181 gtattactaa ggctcgtcaa atggttgaat ttaacggtct tggacactca gcagctatcc
    18241 acacagctga cgaagaattg actaaagaat ttggtaaagc tgttaaagct attcgtgtta
    18301 tctgtaactc accttctact tttggtggta tcggggacgt ttacaatgcc ttcttgccat
    18361 cattgacact tggatgtggt tcttacggac gcaactcagt tggggataac gttagtgcca
    18421 ttaacctctt gaatatcaaa aaagtcggaa gacggagaaa taacatgcaa tggatgaaac
    18481 ttccttcaaa aacatacttt gaacgtgatt caattcaata ccttcaaaaa tgtcgtgacg
    18541 ttgaacgtgt catgatcgtt actgaccatg ccatggtaga gcttggtttc cttgatcgta
    18601 tcatcgaaca actggacctt cgtcgcaata aggttgttta ccaaatcttt gcggatgtag
    18661 aaccggatcc agatatcaca actgtaaacc gtggtactga gattatgcgt gccttcaaac
    18721 cagataccat catcgcactc ggtggtgggt ctccaatgga tgctgccaaa gtaatgtggc
    18781 tcttctacga gcaaccagaa gtggacttcc gtgaccttgt ccaaaaattc atggatatcc
    18841 gtaaacgtgc cttcaagttc ccattgcttg gtaagaagac taaattcatc gcgattccaa
    18901 ctacatctgg tacaggatct gaagtaacac catttgccgt tatctctgat aaagcaaaca
    18961 accgtaaata cccaatcgct gactactcat tgacaccaac tgtggcaatc gtagatcctg
    19021 ctttggtatt gacagttcca ggatttgttg ctgctgatac tggtatggac gtattgactc
    19081 acgcgacaga agcatacgta tcacaaatgg ctagtgacta cactgatggt ttagcacttc
    19141 aagccattaa attggtcttt gaaaatctcg aaagctcagt taagaatgca gacttccact
    19201 cacgtgagaa aatgcataac gcttcaacaa tcgctggtat ggcctttgcc aatgccttcc
    19261 taggtatttc tcactcaatg gcccataaga ttggtgcgca attccacaca atccacggtc
    19321 gtacaaatgc tatcttgctt ccatacgtta tccgttacaa cggtacacgt ccagctaaga
    19381 cagcaacatg gcctaagtac aactactacc gtgcagatga aaaataccaa gatatcgcac
    19441 gcatgcttgg acttccagct tctactccag aagaaggggt tgaatcttac gcaaaagctg
    19501 tctacgaact cggtgaacgt attgggatcc aaatgaattt tagagaccaa ggaattgacg
    19561 aaaaagaatg gaaagaacat tctcgtgaat tagccttcct ggcttatgaa gaccaatgtt
    19621 caccagctaa cccacgtctt ccaatggtag accatatgca agaaatcatc gaagatgcat
    19681 actatggcta caaagaaaga ccaggacgcc gtaaataatt gtttatcagt ctagaagcaa
    19741 gacaaaaact caatttgagg gaaagatcca gtaatttttc tatgataaaa ggcatcctat
    19801 caaggttttt gaacacctga taggatgcct ttttatgata ttgaggcctt tttgcccttt
    19861 ttgaaaaact agaatagaaa caaaatatat aatagattga aactggaata gtacacttct
    19921 gcttctaaaa cattgttaga attcgatttg actgtcctga tcgatttgtc ctattcctat
    19981 ttcattttac tatataaaaa atatagtata gtagactgaa tctaaaatag tacgaaacaa
    20041 ttgctaaaac atttatagaa attaatttta ctttcctgat agagttgttc acatcttatt
    20101 tcaattcact atagtttaat ttaagagtag tatttactaa ggcccaatta aaatcaaaga
    20161 gcaaactaga aaacgagtgc cattcagctc aaaacactga tttgagattg cagataagac
    20221 tagcccctca ttaacaggtt tacgataaaa cgatgacaag gtgtgttgct ttttgatttc
    20281 taaagagtat aatgatagat ctctataaaa taagtgcgaa ggaaatgagc ttttatagtc
    20341 ctttcgtttt aaaatactat ctcagatgtt cttatatcga caagaagttt ttgagtcatt
    20401 ccctcatcat acatattaaa taaatagtgg ctcattcaat tttttactag aataataagc
    20461 tagtatagta aactgaaata agatataaac aaataaattg gagcttaaca tctatttcca
    20521 gcaatttttt agaaactgca gtggactatt ctaaattcaa cacattataa aaactagagt
    20581 aaaagaaaag gattggatct tgtgtaatgc aggatctaat cctttcaatc attttgtcca
    20641 acttttggag gttcctacaa tgtagccgtc attaataaag acagatggga acgacagtgt
    20701 tcctatttat tttgatagag atcgatgaat tctttagata gcaactgaat aatctctgtt
    20761 gaagccattt ggtcttctgc atgcataaat agcaaggaga atcctatttt ttctccagta
    20821 gcttcttttt gtatgagatt agagtgaatc ttgtgcgctt ctactaagga gtcttccgct
    20881 tcttcaactt taattttcgc ttcttttaaa tttcctgcct tagctagttg gatggcttca
    20941 ataaaggatg atttggctgc tccactattg gcaatgagct gaaaacagat atattccatt
    21001 tcttctgtca tcttatttct cctatccatg caagtgcttg ttccagaact tttgctccat
    21061 tcatcattcc gtaatcccgc atatcaatgg tatctacagg gatatttcct gcaatttctt
    21121 tcacagcaag taactcataa cgaatttgtg gcccaattag aatgacatct gcttcatgga
    21181 tattcttttt cgcttctgtc attgattttg cttggataga aatttcaatc ccacgttcag
    21241 tcgcactttg ttgcattttt ttaacaagca tacttgtcga cattcccgca ttacatacta
    21301 ataaaatttg tttcataatc ttaaccttcc atttcttgct caacaacttt gtcattaact
    21361 ttgataaatg gaatgtatag aagaactcca agtgcaaaga tgatgaattg aactagaact
    21421 gctctcacgt cccctgctgt tgctaaccat gcatttaaga atactggtgt agtccaagga
    21481 acttgtataa atgcaggact catgaatcct gtaactgttg ctaagtagct gattaaaata
    21541 ccaaggactg gaactgtgat aaatggaata gctaatgaaa tgttataaac gattgggtaa
    21601 ccgaataata ctggttcatt gatattgaag ataccaggtc caaaagataa tttagccacg
    21661 tttttagaaa cagcattgcg actcactaag aatgttgcta ttaataaaca taatgtagat
    21721 ccactaccac ccattaaagc gaatgtttgt atttgtgata agttgatgat gtgtggaatg
    21781 gcttgtccat tatttgctgc agtgatgttt tcagtaatgt taattaatag taatggttct
    21841 aggatggcac tgtaaataac tgcttggtga ataccaaata gccataacat atttcctaaa
    21901 gagtaaataa taatgacccc gattaagctt gtaccaatat gacgaattgg ttcttgaata
    21961 aagattgtaa tgattgagat taagttcatt ccagttatat tgaataataa tgctgaaaca
    22021 atcccaaata aggagatgac agtcatgact ggaagtaata cgctaaatga tctactaaca
    22081 gctggtggaa tattttcacc aaggttcatt tgtaaagctt taacgtttga taattcaatg
    22141 aataattctg ttgcaataat cgctacgata accccggcga acattgcgcc tgtacctgtg
    22201 ttgttgaatg aaagaacacc tgaaatgttt acagcatctt ttgctccgtc aggaactaca
    22261 gaaactgtat ttggcatcat cacaattaaa gaaactaatg atagcattga tgctgctgac
    22321 gggttttcga aatctctgtt tttagctaag aaataaccaa ccattacagc aataatcata
    22381 cctgaaatac ttaaagtacc gtttgcaatt gttattcccc aatattggaa ttttgttaat
    22441 gtatcccctt ggaaaatcca cttaaatacc gtgttgttca aaagaacgat taaacctgcc
    22501 aaaatatata atggcattac tgttacgaat gcatctctta gggtttttaa atgaatttgg
    22561 ttccctagtt taccagcaaa ggtggcaaat tgatctataa attttgagtt tttcatctga
    22621 atatctcctc tctttactcc tcaatttcta cttcaaaacc gttattgtca cttactttgc
    22681 gataccatct tcctgagctc ttgatggttc tcttttgcgt ttctaaatca acggagataa
    22741 atccgtaacg attcttatat gcattattcc aagaccagca atcaaatgcg gtccaagcgt
    22801 ggtatccaaa acagagactt ccctcttcaa tggctttatg tagccatctt aaatgttctt
    22861 cataaaattc aatacgatac acgtcatcga taactccatt ttcatcgata aaccgtgctt
    22921 cgttttcaac acccattccg ttctcactga taaaccatgg gatattacca tattcttcct
    22981 tcacaatcat agcaatatca taaatggctt tcggaaaaat ttcccaacca cgatatggat
    23041 tcatgcgacg ctccggccat tcatactctt tgaagtattg gtctggcatc cagggcgtct
    23101 gatattcctc aggatttgct tgtgcttgaa cacgttttgg atggtagtag tttactccaa
    23161 gaaaatcaac cgtatttgat ttcatcagtt gaagctcttt ttcggtatga ctccataaca
    23221 cgccatctct ctctagctgt tttaccaatc tttctgggaa agttccttta acagctggat
    23281 tcaagaagac tttgttaaag aagtcttctg taaatcgact tgcttctaag tcttctggag
    23341 aattacttct tggataagca ggtgtcaagt ttaaaataat cccaatcttt ccatcaagtc
    23401 ctaatgagcg atatagttga atcacttttg cactagcaag gtttagatta tagatgactt
    23461 gtacggcctc ttttcccttt ccttttagat ttggataatg gaaagcatat aagtatcctg
    23521 cttctggaat gaccattggc tcattgaaag ttgtccagta atgaacctta tctccaaagc
    23581 atgtgaaagc agtcttggca aacttcacga ataactccac tacatgtttg ctttcccaac
    23641 caccgtattt ttgaagaagt tccactggta aatcaaaatg atgtaaattc atcacaagat
    23701 ccatctggtt ctttttagct tcttcaatga tggcattgta gaaagcaata ccttttggat
    23761 caggctcacc tgtctctaaa ttcttgatga gtcgactcca ttggatggaa gtgcggaaag
    23821 aattaactcc aatttccttc atcaagtgga aatcttcggt gtaagtatga aaaaagttac
    23881 tggctacaag aggtccgaca ttatcgaaaa aatcttctgg atgcgttttg aaccagtagt
    23941 ccatcacatt ttcatgtact tttccatatt gaccttctgt ctgaggtccg ctagaagcag
    24001 ctccccacca aaacagatta ggaaatacta actttttttt catgctcaac ctcctttcta
    24061 ttatgctata cataaagtat agcataattt taaaatttgt ctagacattt ttaaaaattg
    24121 ttgatacata tattgtgttt gcctcatttc ttgaactttg ttatactact attagaatat
    24181 tatagagaga accagattaa atgagtacaa aatatttatt tatttacaat gagattcgtg
    24241 aaaagattct ctgtaataaa tataccatga acgaacaatt gcctgatgaa atgacattag
    24301 ctaaacagtt tgcctgtagt cgaatgacga tcaaaaaagc tttagacttg ttagtttctg
    24361 agggcttaat ttttagaaaa cgtgggcagg gaacctttgt tctctctcgt ggcagctcaa
    24421 aaagaaaatt aatcgttcca gaaagagata tccggggact gacaaaaata tctgaagatg
    24481 ctcattctac aattgactcg aggattattc acttcaaatt agaatttgca aatgaatttt
    24541 tagcagaaaa actacaggtc gctttgcaga gtccagttta taatatttac cgcctgcgta
    24601 ttattgacgg taaaccttat gttctggaac aaacttatat gagtaccgat gttattccag
    24661 gtattactga agatatttta caaaaatcga tttacaatta cattgaagga aagttaggat
    24721 tgcatattgc cagtgctaca aaaatcttgc gagcttcttc tagttcagaa aatgagcaac
    24781 attacttgca gctccttcca acagaaccgg tatttgaagt agaacaagtg gcttatttgg
    24841 ataacggaac tccgtttgag tactcgatta gtcgtcatcg ctatgattta tttgaattta
    24901 attcttttgc attacgacat tcctcctagg agaaaatgtg aaaatgaagc caatctttta
    24961 caggctctag tttaagaaaa atttaaaaca gggcaagaag gtcccatcta tgcttaaatg
    25021 gtttctcttt tctaaataag atggctttaa aagagtgatc gttttatcca tcatgttgaa
    25081 aaatatcttc gtatagctta tagagtaggt actgaaattg ttcacctgat ctacttctta
    25141 tagttattta gttttaaata gtgtttcaaa cattcttaca ctgacgagaa gtttttgagt
    25201 cttttcttgt aacacatata gtatactgag gttagaatag tagactgtga cttctaacaa
    25261 attgctagaa atgaatttca atctcccaat ttatttgctt atatattatt ttaatatatt
    25321 aaataaattc tggatcataa tcatttaaaa aaattttatt tttttatttt tcattacgaa
    25381 taatatagat gaaggggaaa gagtatgaaa acagaactgt ttcttttgct attagttcaa
    25441 aaggagaaaa aatgaaagta gaaaatattt cgtatagggt ggatcatcgt atattgtttg
    25501 ataatatttc ttttgatact tcgagttcag acgtgacatt aattactggt aaaaatggta
    25561 caggaaagtc aactttacta tagtggattg aaactagaat agtacacatc tacttctaaa
    25621 atattgttag aaatcgattt gactatcctg atctatttgt cctgttctta tttcatttca
    25681 ctatatctca aattgagtat gacgaagtgc gctcccatgt cctgggaacg cactttcttc
    25741 atatttttca tattcttgaa tccatcgata aagactattg ggatgaattt ttaaagttga
    25801 actaatcatt tttacaggat gaggtttaca gcagagagtt tgaaggcttt atcaaaggtt
    25861 tttcttggca taatgacttt tcctcgtttc cacttaattt tgtgtctact ttattatacc
    25921 aagtccaccc ttaagttaga taataaatct aacttaagga agctagaagg atgagaatcc
    25981 aggtggtcaa gagtcccaaa cttaagctga ttgggacacc cagaataatt tgctttttga
    26041 aggcaaggcc acgttcctct atattgggaa gtgagagttg aatgagagaa ccagctgatg
    26101 aaaagggtga gatattagta gatagagcgc caataacggt ggctgttgtg agtaagtgaa
    26161 tatcaatctg gggattttga gcactgatga tagcaatgat gggaaagagg gctggagcta
    26221 caacggatag ggtggaacta aagagtgaca tcaccccggc tatcacacaa aagaacagag
    26281 gtaaccagaa atgaggaatg gatgttgtca tgaggtgccc tatcagtgtg actaaacctg
    26341 acttgaccgc tagagacatt agtaagctca tgccgcagag catgataatt gtagcccagg
    26401 gaactttagc caaaatggct tcttgcttcc ctaatttgag ccttaaggcg aggcagacca
    26461 tgagtattga gacaaagcca atatcaaatg tttttcgata agtagctatc caggcgatgt
    26521 ttgggaaaat gagatgcaac aagggaaaaa gccaaaccaa aaccatgctg ctgatcatga
    26581 gcaaggtggt ttgtctttga accttgctga ggagtggtgg ttggtcaata gtcaaggatg
    26641 agtttgttct tcccttacta tagtgactgt aacaggataa taaaagcaag acaatgagtg
    26701 ggtagataat gctgacgata aagatatgat tgccaagtga aaaagcttgc tcttcccatc
    26761 ccatttgctt aaacaggcct tgaaagacaa tgcctgagct actggttatc aaattagccc
    26821 ctcctgaagc tccccaattg acggcttgag ctccaatcaa agggtgtttg tccgcttttt
    26881 gacagagagt aatcgctaga ggacagcaaa cggccatagt agtgaaaaat ccagcaccta
    26941 aagcagacaa aagggttgcc atcaggtata aaatcatgta gagggcgtta gggtaggtgc
    27001 gtgtgcggta gagaatgtgt tgagccaaaa catcaagagt accgttagtt attgcaaagt
    27061 tataaaagag agagacgcta aaaatggtaa aaaagagtga ggttggccaa aaatgaagaa
    27121 gttctttggg gcttaatccc atgagagtgg ttgcgatgag gtaagaaaaa gcaatagcca
    27181 gcaggccaat attgattttg gtgcggtaac caattccaat ggctagagca atggcgctaa
    27241 tcattattaa atgaatcatt gaattgtcct ttcagttaga atatggaaat aggttggcaa
    27301 ttttggcgct caaaagacca cctgtttcct attggtactt gactattata cacaaaaaaa
    27361 atacaattgt cttgacaatt gtattgacac ttgttagaat taaaaatgag gtattcaggc
    27421 ttgtgatttc ctatggaagt taatagtgat tgcctctaat gcttacaagt gatattaaaa
    27481 atagaggacc tagtgatgtc aatcatttca actgatttaa ccccttttca aatagatgat
    27541 acattgaaag cagccttgcg agaagatgtt cattccgaag attacagtac caatgccatt
    27601 tttgatcatc atggccaagc caaggtgtcg ctttttgcca aggaagctgg tgttttagcg
    27661 gggctaaccg tttttcaaag ggtttttacc ctatttgatg ccgaggtgac cttccagaat
    27721 cctcatcaat ttaaggatgg ggatcgtttg actagtggcg atttggtttt agaaatcata
    27781 ggctcggtga gaagtctctt aacatgtgaa cgcgttgcct tgaatttttt acaacattta
    27841 tcagggattg cttcgatgac agctgcttat gtagaagcct taggcgatga ttgcattaag
    27901 gtatttgata ctcgaaaaac tactcctaat ttacgtcttt ttgagaaata tgcagtgaga
    27961 gttggcggtg gctataatca tcgctttaat ttatcagatg ctatcctgct aaaagacaat
    28021 cacattgcgg cagtaggtag tgttcaaaag gcaattgctc aagcgcgtgc ctatgcccct
    28081 tttgtgaaaa tggtcgaggt ggaagtggaa agccttgctg ctgccgaaga agctgcggcg
    28141 gcgggtgctg atattatcat gttggataat atgtcattgg aacagattga acaggccatt
    28201 accctaattg caggacgttc tcggattgaa tgttctggaa atattgatat gaccactatt
    28261 agccgttttc gtggtttagc gattgattac gtctccagtg gtagtttaac ccatagtgct
    28321 aagagtcttg atttttccat gaaggggtta acctaccttg atgtctaagt tgtaaaataa
    28381 actaactttt taaaggatgt ctttcctcta gaacgagttt tatgtcagat agtttaaacg
    28441 cctcttcaa
//
LOCUS       DAVBDR010000025        25876 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.025, whole genome shotgun sequence.
ACCESSION   DAVBDR010000025 DAVBDR010000000
VERSION     DAVBDR010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25876)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25876)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25876
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.025"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            complement(146..397)
                     /locus_tag="VQ540_001084"
     CDS             complement(146..397)
                     /locus_tag="VQ540_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2544898.1"
                     /translation="MPKTKTLAELADVILWSFDFANDHAHAFFMDNVEWSHADSYFLS
                     FVSDDVEERYIENVYLDSLSVKQKFKFIFDFGDEWRFEC"
     gene            complement(687..2567)
                     /locus_tag="VQ540_001085"
     CDS             complement(687..2567)
                     /locus_tag="VQ540_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HET2544899.1"
                     /translation="MVRFTGLSPKQTQAIEVLKGHISLPDVEVAVTQSDQASISIQGE
                     EGHYQLTYRKPHQLYRALSLLVTVLAEADKVEIEEQAAYEDLAYMVDCSRNAVLNVAS
                     AKQMIEVLALMGYSTFELYMEDTYQIEGQPYFGYFRGAYSAEELQEIEAYAQQFDMTF
                     VPCIQTLAHLSAFVKWGVKEVQELRDVEDILLIGEEKVYDLIDGMFATLSKLKTRKVN
                     IGMDEAHLVGLGRYLILNGVVDRSLLMCQHLERVLDIADKYGFHCQMWSDMFFKLMSA
                     DGQYDRDVEIPEETRVYLDRLKDRVTLVYWDYYQDSEEKYNRNFRNHHKISHDLAFAG
                     GAWKWIGFTPHNHFSRLVAIEANKACRANQIKEVIVTGWGDNGGETAQFSILPSLQIW
                     AELSYRNDLDGLSAHFKTNTGLTVEDFMQIDLANLLPDLPGNLSGINPNRYVFYQDIL
                     CPILDQHMTPEQDKPHFAQAAETLANIKEKAGNYAYLFETQAQLNAILSSKVDVGRRI
                     RQAYQADDKESLQQIARQELPELRSQIEDFHALFSHQWLKENKVFGLDTVDIRMGGLL
                     QRIKRAESRIEVYLAGQLDRIDELEVEILPFTDFYADKDFAATTANQWHTIATASTIY
                     TT"
     gene            complement(2561..3430)
                     /locus_tag="VQ540_001086"
     CDS             complement(2561..3430)
                     /locus_tag="VQ540_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HET2544900.1"
                     /translation="MTIATIDIGGTGIKFASLTPDGKILDKTSISTPENLEDLLAWLD
                     QRLSEQDYSGIAMSVPGAVNQETGVIDGFSAVPYIHGFSWYEALSSYQLPVHLENDAN
                     CVGLSELLAHPDLENAACVVIGTGIGGAMIINGRLHRGRHGLGGEFGYMTTLAPAEKL
                     NNWSQLASTGNMVRYVIEKSGHTDWDGRKIYQEAAAGNILCQEAIERMNRNLAQGLLN
                     IQYLIDPDVISLGGSISQNPDFIQDVKKAVDNFVDTYEEYTVAPVIQACTYHADANLY
                     GALVNWLQEEKQW"
     gene            complement(3514..6159)
                     /locus_tag="VQ540_001087"
     CDS             complement(3514..6159)
                     /locus_tag="VQ540_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000432759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HET2544901.1"
                     /translation="MENVVVHIISHSHWDREWYLPFESHRMQLVELFDNLFDLFENDP
                     EFKSFHLDGQTIVLDDYLQIRPENRDKVQRYIDEGKLKIGPFYILQDDYLISSEANVR
                     NTLIGQQEAAKWGKSTQIGYFPDTFGNMGQAPQILQKSGIHVAAFGRGVKPIGFDNQV
                     LEDERFTSQFSEMYWQGVDGSRVLGILFANWYSNGNEIPVDKDEALTFWKQKLSDVRA
                     YASTNQWLMMNGCDHQPVQKNLSEAIRVANELFPDVIFVHSSFDEYVQAVEGALPEHL
                     STVTGELTSQETDGWYTLANTSSSRIYLKQAFQENSNLLEQVVEPLTIITGGHNHKDQ
                     LTYAWKTLLQNAPHDSICGCSVDEVHREMETRFAKVNQVGNFVKSNLLNEWKGKIATD
                     KAQSDYLFTVINTGLHDKVDTVSTVIDVATCDFKELHPTEGYKKMAALILPSYRVEDL
                     DGRPVEATIEDLGANFEYDLPKDKFRQARIARQVRVTIPVHLAPLSWTTFQLLEGKQE
                     HREGIYQNGVIDTPFVTVSVDDNITVYDKTTHEAYEDFIRFEDRGDIGNEYIYFQPKG
                     TEPIFAELKGHEVLENTDRYAKILLKHELTVPVSADEKLEEEQQGIIEFMKREAGRSE
                     ELTNIPLETELIVFVDNPQIRFKTRFTNTAKDHRIRLLVKTHNTRPSNDSESIYEVVT
                     RPNKPAASWENPENPQHQQAFVSLYDDEKGVTVSNKGLNEYEILGDNTIAVTILRASG
                     ELGDWGYFPTPEAQCLREFEVEFALECHQAQERFSAFRRAKALQTPFTSLQLARQEGS
                     VVATGSLLSHSVLSIPQVCPTAFKVAENEEGYVFRYYNMSQENVHISEHQQTILDLLE
                     RPYPVHSGPLDPQEIRTEFIKKEEI"
     gene            complement(6250..7530)
                     /locus_tag="VQ540_001088"
     CDS             complement(6250..7530)
                     /locus_tag="VQ540_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HET2544902.1"
                     /translation="MIYSKEIVREWLDEVAERAKDHPEWVDVFERCYTDTLDNTVEIL
                     EDGSTFVLTGDIPAMWLRDSTAQLRPYLHVAKRDALLRQTIAGLVKRQMTLVLKDPYA
                     NSFNIEENWKGHHETDHTDLNGWIWERKYEVDSLCYPLQLAYLLWKETGETSQFDETF
                     VAATKEILHLWTVEQDHKNSPYRFVRDTDRKEDTLVNDGFGPDFAVTGMTWSAFRPSD
                     DCCQYSYLIPSNMFAVVVLGYVQEIFAALNLADSQSVIADAKRLQDEIQEGIENYAYT
                     TNSKGEKIYAFEVDGLGNASIMDDPNVPSLLAAPYLGYCSIDDEVYQATRRTILSSEN
                     PYFYQGEYASGLGSSHTFYRYIWPIALSIQGLTTRDKAEKKFLLDQLVACDGGTGVMH
                     ESFHVDDPTLYSREWFSWANMMFCELVLDYLDIR"
     gene            7701..9785
                     /locus_tag="VQ540_001089"
     CDS             7701..9785
                     /locus_tag="VQ540_001089"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000803403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HET2544903.1"
                     /translation="MKPLLETIDTRFGTASKHAFSRGNTLPYTGVPFGMNYFVPQTSD
                     QDGSWFFDPHLPIFQGIRLTHQPSPWIGDYSWLLLTPVTSQLGGDSLFHRQSSYDIDK
                     ACFQPHYLKLFSLRYQIETQLTPTCYGASIRLNQKQGKALSLYLHAADELTVEQVDKR
                     TLALRQEGKTETNKNSLTMFTALQMNTDILAISQEAGDWRIDLASSQTEMQLATSFIS
                     PSQALINLPQEDFDSCKTSAQADWENLLHRFDIIETGEADRTFFDHCLYRLFLFPQTF
                     YEVDESGKAIHMDLATGTVKPGVLFSNNGFWDTFRTTFPLFALIIPEHYQRFLEGFLN
                     SYRDTGFLPKWLAPDERGMMPGTLLDGIIADSACKDMAPDLEGELFQAMLETASKADP
                     LGINGRHGLAQYQELGYLSTDHHESVSHTLDYAYSDFCIASCAKKLENIEIAETYKAA
                     SQNYRQLFDAETGYMRARDNQGNFHPDFSPYSWGRDYAECSAIQATLGVLHDIPGLIQ
                     LMGGKETFSNYLLKACQDAPLFETTGYGYEIHEMSEMATAPFGQIAISNQPSFHIPYL
                     FRYSDYPDYTALLIKTLRQKAFHPSWEAYPGDEDNGSLSAWYIWSALGFYPTCPGKPS
                     YDLGIPLFDHLRVYLAKENKWLDIHTEQNHSHFNFVKECRLDKTLVSTIQHQDLLKAE
                     QLTFTLSWLPNH"
     gene            complement(9825..11504)
                     /locus_tag="VQ540_001090"
     CDS             complement(9825..11504)
                     /locus_tag="VQ540_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000721501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-fucosidase"
                     /protein_id="HET2544904.1"
                     /translation="MKKIKPHGPLPSQTQLAYLGDELAAFIHFGPNTFYDQEWGTGQE
                     DPERFNPSQLDAREWVRVLKETGFKKLILVVKHHDGFVLYPTAHTDYSVKVSPWRRGK
                     GDLLLEVSQAATEFDMDMGVYLSPWDAHSPLYHVDREADYNAYYLAQLKEILSNPNYG
                     NAGKFAEVWMDGARGEGAQKVNYEFEKWFETIRDLQGDCLIFSTEGTSIRWIGNERGY
                     AGDPLWQKVNLDKLGTEAELNYLQHGDPSGTIFSIGEADVSIRPGWFYHEDQDPKSLE
                     ELVEIYFHSVGRGTPLLLNIPPNQAGLFDAKDIERLYEFATYRNELYKEDLALGAEVS
                     GPALSADFDCRHLTDGLETSSWASDADLPIQLELDLGSPKTFDVIELREDLKLGQRIA
                     AFHVQVEVDGVWQEFGRGFTVGHKRLLRGPLVEAQKVRVMITEAQSIPVLTKISLYKT
                     PGLSKKEVVQELAFAEKSLAVAKGETLHFRIERSESSSSLEAKISIQPGTGVHGVAYQ
                     DEIYVLAFQAGETEKRLTLPTLYFAGDKTLDFYLNLTVDGQLVDQLQVQVS"
     gene            12259..13488
                     /gene="arcA"
                     /locus_tag="VQ540_001091"
     CDS             12259..13488
                     /gene="arcA"
                     /locus_tag="VQ540_001091"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000094613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HET2544905.1"
                     /translation="MSSHPIQVFSEIGKLKKVMLHRPGKELENLLPDYLERLLFDDIP
                     FLEDAQKEHDAFAQALRDEGIEVLYLEQLAAESLTSPEIRDQFIEEYLDEANIRDRQT
                     KVAIRELLHGIKDNQELVEKTMAGIQKVELPEIPDEAKDLTDLVESDYPFAIDPMPNL
                     YFTRDPFATIGNAVSLNHMFADTRNRETLYGKYIFKYHPIYGGKVDLVYNREEDTRIE
                     GGDELILSKDVLAVGISQRTDAASIEKLLVNIFKKNVGFKKVLAFEFANNRKFMHLDT
                     VFTMVDYDKFTIHPEIEGNLHVYSVTYENEKLKIVEEKGDLAELLAQNLGVEKVHLIR
                     CGGGNIVAAAREQWNDGSNTLTIAPGVVVVYDRNTVTNKILEEYGLRLIKIRGSELVR
                     GRGGPRCMSMPFEREEV"
     gene            13546..14562
                     /gene="argF"
                     /locus_tag="VQ540_001092"
     CDS             13546..14562
                     /gene="argF"
                     /locus_tag="VQ540_001092"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HET2544906.1"
                     /translation="MTNSVFQGRSFLAEKDFTRAELEYLIGLSAHLKDLKKRNIQHHY
                     LAGKNIALLFEKTSTRTRAAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQRMVEELAEFSGVPVWNGLTDEWHPTQMLADYLTVQENFGRLEGLTLV
                     YCGDGRNNVANSLLVTGAILGVNVHIFSPKELFPEKEIVELAEGFAKESGAHVLITED
                     ADEAVKDADVLYTDVWVSMGEEDKFAERVALLKPYQVNMDLVKKAGNENLIFLHCLPA
                     FHDTHTVYGKDVAEKFGVEEMEVTDEVFRSKYARHFDQAENRMHTIKAVMAATLGNLY
                     IPKV"
     gene            14727..15674
                     /gene="arcC"
                     /locus_tag="VQ540_001093"
     CDS             14727..15674
                     /gene="arcC"
                     /locus_tag="VQ540_001093"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003025409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HET2544907.1"
                     /translation="MANRKIVVALGGNAILSSDPSAKAQQEALVETAKHLVKLIKNGD
                     DLIITHGNGPQVGNLLLQHLASDSEKNPAFPLDSLVAMTEGSIGFWLKNALQNALLDE
                     GIEKNVASVVTQVIVDKNDPAFVNLSKPIGPFYSEEEAKAEAEKSGATFKEDAGRGWR
                     KVVASPKPVDIKEIETIRTLLNNGQVVVAAGGGGIPVVKENNGHLTGVEAVIDKDFAS
                     QRLAELVDADLFIVLTGVDYVFVNYNKPNQEKLEHVNVAQLEEYIKQDQFAPGSMLPK
                     VEAAIAFVNGRPEGKAVITSLENLGALIESESGTIIEKG"
     gene            15883..17394
                     /locus_tag="VQ540_001094"
     CDS             15883..17394
                     /locus_tag="VQ540_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004191872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HET2544908.1"
                     /translation="MSEKAKKGFKMPSSYTVLLIIIAIMAVLTWFIPAGAFIEGIYEA
                     QPQNPQGIWDVLMAPIRAMLGTHPEEGSLIKETSAAIDVAFFILMVGGFLGIVNKTGA
                     LDVGIASIVKKYKGREKMLILVLMPLFALGGTTYGMGEETMAFYPLLVPVMMAVGFDS
                     LTGVAIILLGSQIGCLASTLNPFATGIASATAGVGTGDGIVLRLIFWVTLTALSTWFV
                     YRYADKIQKDPTKSLVYSTRKEDLKHFNVEESSSVESTLSSKQKSVLFLFVLTFILMV
                     LSFIPWTDLGVTIFDDFNTWLTGLPVIGNIVGSSTSALGTWYFPEGAMLFAFMGILIG
                     VIYGLKEDKIISSFMNGAADLLSVALIVAIARGIQVIMNDGMITDTILNWGKEGLSGL
                     SSQVFIVVTYIFYLPMSFLIPSSSGLASATMGIMAPLGEFVNVRPSLIITAYQSASGV
                     LNLIAPTSGIVMGALALGRINIGTWWKFMGKLVVAIIVVTIALLLLGTFLPFL"
     gene            17416..18747
                     /locus_tag="VQ540_001095"
     CDS             17416..18747
                     /locus_tag="VQ540_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000686986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase"
                     /protein_id="HET2544909.1"
                     /translation="MKIDITNQVKDEFLISLKTLISYPSVLNEGENGTPFGQAIQDVL
                     EKTLEICRDIGFTTYLDPKGYYGYAEIGQGAELLAILCHLDVVPSGDEADWQTPPFEA
                     TIKDGWVFGRGVQDDKGPSLAALYAVKSLLDQGIQFKKRVRFIFGTDEETLWRCMARY
                     NTIEEQASMGFAPDSSFPLTYAEKGLLQVKLHGPGSDQLELEVGGAFNVVPDKANYQG
                     PLYEQVCNGLKEAGYDYQSTEQTVTVLGVPKHAKDASQGINAVIRLATILAPLQEHPA
                     LSFLATQAGQDGTGRQIFGDIADEPSGHLSFNVAGLMINHERSEIRIDIRTPVLADKE
                     ELVELLTRCAQNYQLRYEEFDYLAPLYVAEDSKLVSTLMQIYQEKTGDNSPAISSGGA
                     TFARTMPNCVAFGALFPGAKQTEHQANECAVLEDLYRAMDIYAEAVYRLAT"
     gene            complement(19153..19443)
                     /locus_tag="VQ540_001096"
     CDS             complement(19153..19443)
                     /locus_tag="VQ540_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000501069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2544910.1"
                     /translation="MGALGYYEGFVPYVSNQYKNQAEEEGKPLSDKYIFEKILGKTYA
                     AFKKDQINERVEKLGKLKPITINYNGKSEVIDSKEKLQELMNKAVKDEVAQI"
     gene            complement(19431..19682)
                     /locus_tag="VQ540_001097"
     CDS             complement(19431..19682)
                     /locus_tag="VQ540_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657761.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HET2544911.1"
                     /translation="MKEFQFERKQRFSLRKYAIGACSVLLGTSLFFAGMGDQPVQDTE
                     TSSALISSHYLDEQDLSEKLKSELQWFELENKLLNLWEH"
     gene            complement(20081..20965)
                     /locus_tag="VQ540_001098"
     CDS             complement(20081..20965)
                     /locus_tag="VQ540_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HET2544912.1"
                     /translation="MIFLIVCVLLLVIVTLSTVYVVRQQSVAIIERFGKYQKVANSGI
                     HIRLPFGIDSIAARIQLRLLQSDIVVETKTKDNVFVMMNVATQYRVNEQSVTDAYYKL
                     IRPESQIKSYIEDALRSSVPKLTLDELFEKKDEIALEVQHQVAEEMTTYGYIIVKTLI
                     TKVEPDAEVKQSMNEINAAQRKRVAAQELAEADKIKIVTAAEAEAEKDRLHGVGIAQQ
                     RKAIVDGLAESITELKEANVGMTEEQIMSILLTNQYLDTLNTFASKGNQTIFLPNTPN
                     GVDDIRTQILSALRAEKK"
     gene            complement(21110..22261)
                     /locus_tag="VQ540_001099"
     CDS             complement(21110..22261)
                     /locus_tag="VQ540_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HET2544913.1"
                     /translation="MAIFYVPAVNLIGKGVVNEVGPYIKELGYKKALLVTDKYIEGSD
                     ILPKTLKPLDTEGIEYVIFSDVEPNPTCKNVTDGVAALQEHRCDFIISLGGGSPQDAA
                     SCISIMATNGGKPQDYEGLHKSAKKGLPVVAINTTAGTSAEITINYVITDEERKVKMV
                     MVDKNSLALISVNDPELMLSKPQALTAATGMDALTHAVEALVTPGAYDVTKKLSIGAI
                     ELIKEYLPRAVENGHDIEAREGMVNAIFLGGMSFNNAGLGYVHSMAHQLGAVYNLPHG
                     VCCAMLLPVIEHENAKRVPEAFRNVAKALGLHVEGKSDQECADYAIVEIEKLSETVGI
                     PKKLTELGIEEKDFDFEYLSKNALIDACAPGNPFMPTLEETIAFYKELF"
     gene            complement(22407..24173)
                     /locus_tag="VQ540_001100"
     CDS             complement(22407..24173)
                     /locus_tag="VQ540_001100"
                     /EC_number="5.3.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fucose isomerase"
                     /protein_id="HET2544914.1"
                     /translation="MIQHPRIGIRPTIDGRRQGVRESLEVQTMNMAKSVADLISSTLK
                     YPDGEPVECVISPSTIGRVPEAAASHELFKKSNVCATITVTPCWCYGSETMDMSPDIP
                     HAIWGFNGTERPGAVYLAAVLASHAQKGIPAFGIYGRDVQEANDTDIPEDVKEKLLRY
                     ARAALATGLMRDTAYLSMGSVSMGIGGSIVNPDFFQEYLGMRNESVDMTEFTRRMDRG
                     IYDPEEFERAMVWVKEHIKEGVDRNREDLILSKEEKEKQWEFVIKMFMIGRDLMVGNP
                     RLAELGFEEEAVGHHALVAGFQGQRQWTDHFPNGDFMETFLNTQFDWNGIRKPFVFAT
                     ENDSLNGVSMLFNYLLTNTPQIFADVRTYWSPEAVKRVTGHTLEGCAAAGFLHLINSG
                     SCTLDGTGQATRDGKPVMKPFWELEESEVQAMLENTDFPPANREYFRGGGFSTRFLTK
                     GDMPVTMVRLNLLKGVGPVLQIAEGYTLELPEDVHHTLDNRTDSGWPTTWFAPRLTGK
                     GAFKSVYDVMNNWGANHGAITYGHIGADLITLASMLRIPVNMHNVPEEDIFRPKNWSL
                     FGTEDLESADYRACQLLGPLHK"
     gene            complement(24230..>25876)
                     /locus_tag="VQ540_001101"
     CDS             complement(24230..>25876)
                     /locus_tag="VQ540_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001031112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="discoidin domain-containing protein"
                     /protein_id="HET2544915.1"
                     /translation="NYRTDKTAMWALSGNFDASKSWKKEELELANWISKNYSINPVDN
                     DFRTTTLTLKGHTGHKPQINISGDKNHYTYTENWDENTHVYTITVNHNGMVEMSINTE
                     GTGPVPFPTPDKFNDGNLNIAYAKPTTQSSVDYNGDPNRAVDGNRNGNFNSGSVTHTR
                     ADNPSWWEVDLKKMDKVGLVKIYNRTDAETQRLSNFDVILYDNNRNEVAKKHVNNLSG
                     ESVSLDFKEKGARYIKVKLLTSGVPLSLAEVEVFRESDGKQSEEDIDKITEDKVVSTN
                     KVATQSSTNYEGVAALAVDGNKDGDYGHHSVTHTKADSNAWWQVDLGEEFTVSKVDIY
                     NRTDAEPQRLSNFDVIFLSSSGEEVFRRHFDKVVDGLLSLKVPSVGAKLVKIELKSAA
                     IPLSLAEVEAYGSKRTPKKLSNIALTKETRQSSTDYNGFSRLAVDGNKNGDYGHHSVT
                     HTKGDSPSWWEIDLAQTEELEKLIIYNRTDAEIQRLSNFDIIIYDSNNHEVFKQHIDS
                     LESNNLSIDLKGLKGKKVRISLRNAGIPLSLAEVEVYTYK"
BASE COUNT         7331 a         5790 c         5047 g         7708 t
ORIGIN      
        1 tgaaatacta agcctacaca gactgatttc aattttacca ttcttcatag tcaaaaccat
       61 cataatctgg atattgttct ggcaacgttc caaccgaacg tacgagataa gcttcttcgt
      121 cctctgtctc gatttctctc agcacttagc attcaaaacg ccattcatca ccgaagtcga
      181 aaataaactt aaatttttgt ttgacactta ggctatccag atagacattt tctatgtaac
      241 gttcttcaac atcgtcacta acaaagctaa gaaagtaaga atctgcatga ctccactcaa
      301 cattatccat gaaaaatgca tgagcatgat catttgcaaa atcgaaactc cataaaatca
      361 catctgctag ttccgctaac gtttttgttt ttggaatcta tatatgtcgg tagcaacctt
      421 ttttaatttg acggaaatga tccaagcttc tacagatgct ggcttttcag cttctatttc
      481 ttgttttact aattttaact gtagcatttg aaaccagata attcttctgt ttcacgcgaa
      541 acaccctgcg ccaagcaagg tgttcttgtt tttatactca atgaaaatca aagagcaaac
      601 taggaagcta gctgcaggct gctcaaaaca ctgttttgag gttgtagatg gaagctgacg
      661 tggtttgaag agattttcga agagtattaa gtcgtataaa tcgtcgaagc tgtcgcaatg
      721 gtatgccact ggttagctgt agttgctgcg aaatccttgt ctgcgtagaa gtcagtaaat
      781 ggtaggattt caacttccag ctcgtcgatg cggtcaagct ggccagccag ataaacctcg
      841 atacggcttt ctgctcgttt gatgcgttgc aagagtccgc ccatacggat gtcaactgta
      901 tccaaaccaa agaccttgtt ttctttcagc cattggtgac taaagagggc atggaagtct
      961 tcaatttggc ttctaagttc tggtaattct tgtctggcga tttgttgtaa actttcttta
     1021 tcatccgctt ggtaggcctg acgaatgcgt cgtcccacat ctactttgct acttaaaata
     1081 gcattcaact gggcctgagt ttcaaagaga taagcatagt ttccagcttt ttctttaatg
     1141 ttagcaagcg tctcagcagc ctgagcgaag tgcggtttgt cctgttcagg tgtcatgtgt
     1201 tgatcaagaa tcggacaaag aatatcctga taaaaaacat agcggttggg attgataccg
     1261 ctgagattgc ctggtaggtc tggtaagagg ttggcaaggt caatctgcat aaaatcctca
     1321 accgttagac cagtattggt cttgaagtgc gcagacaaac catctaggtc attgcgatag
     1381 ctgagttctg cccagatttg caagcttggt aggatagaga actgggcagt ttcaccacca
     1441 ttgtctcccc aacccgttac gatgacttct ttaatctgat tggcacggca ggctttatta
     1501 gcctcgatag ccactagacg gctaaaatgg ttgtgaggtg taaagccaat ccacttccaa
     1561 gctccccctg caaatgcaag gtcatggcta atcttgtgat gattgcggaa attacggttg
     1621 tatttttcct cgctatcctg ataataatcc cagtaaacca gagtcacacg gtctttgaga
     1681 cggtctaggt agacacgagt ttcctctgga atttccacat cacggtcgta ctggccatcc
     1741 gctgacatga gtttgaagaa catatcactc cacatctggc agtggaaacc atatttgtca
     1801 gcaatatcca gcacgcgctc caagtgttgg cacatgagga gactacgatc cacaacaccg
     1861 ttcaaaatca ggtagcgtcc caaaccaacc aagtgggctt cgtccatccc gatattgacc
     1921 ttgcgagtct tcagtttaga caacgtggca aacatgccat caatcaggtc ataaaccttt
     1981 tcttcgccaa tgagaagaat gtcctctaca tcacggagct cctgcacttc cttgacaccc
     2041 catttgacaa aggccgacaa gtgggccaag gtctggatgc atggtacaaa ggtcatgtca
     2101 aactgttgag cataggcttc gatttcctgc aactcctctg ctgaataagc tccacggaaa
     2161 tagccaaagt aaggctgccc ttcaatctgg taagtgtctt ccatgtaaag ttcaaaggtt
     2221 gagtagccca tgagagccaa gacctcaatc atctgcttgg cagaagccac attcagcacc
     2281 gcatttcgag aacagtcaac catgtaagcc aaatcttcgt aagctgcttg ttcctcaatc
     2341 tctactttat cagcttctgc tagaactgtt accaacaagg ataaggcacg ataaagttgg
     2401 tgaggtttgc ggtaggtcaa ttgatagtga ccttcctcac cctggataga gatagaggct
     2461 tggtcagact gagtgacagc cacttccaca tctggtagag aaatatgacc ttttaaaacc
     2521 tcaatagctt gcgtttgttt gggactaagt cctgtaaatc ttaccattgc ttttcctcct
     2581 gtagccagtt gacaagagca ccgtagagat tggcatctgc gtgataggtg caggcctgga
     2641 taactggtgc gaccgtgtat tcttcgtagg tatcgacaaa gttatcaaca gccttcttga
     2701 catcttggat aaaatctgga ttttgactga tagagccacc cagactgatg acatctggat
     2761 cgatcagata ctggatattg agcaagcctt gcgccagatt gcggttcatg cgctcaatgg
     2821 cttcttgaca aaggatatta ccagctgcgg cctcttggta aatcttgcga ccgtcccaat
     2881 cagtatgacc agatttttca atcacgtatc gtaccatatt cccagttgat gctagttgcg
     2941 accagttatt aagtttttca gcaggggcaa gggttgtcat gtagccaaat tctccaccca
     3001 agccgtggcg acctcgatga agtctaccat tgataatcat ggctccgcca atccctgtcc
     3061 caatcacgac acaggctgca ttttcaagat ctggatgagc tagtagttca ctgagtccaa
     3121 cgcagttggc atcattttct aaatggacag gtagctgata agagctaagc gcctcatacc
     3181 aagaaaagcc atggatgtag ggcaccgcac tgaagccatc aatcacacct gtctcttgat
     3241 tgactgcacc tggaacgctc atagcaatcc cactgtaatc ctgttctgac aagcgttgat
     3301 ctagccacgc tagtaaatcc tccaagtttt caggcgttga aatacttgtc ttatccagta
     3361 ttttcccatc aggagtcaga ctggcaaact taatcccagt ccctccgata tcaatcgttg
     3421 caatggtcat tgtttttacc ataaaaaggg gcgaatcagc agttagttct tactttttcg
     3481 cccctccttt cttttgatgt ttactttttg aaattaaatt tcttcttttt tgatgaattc
     3541 tgtacgaatc tcttgtggat ccaatggtcc tgaatgaact ggatatggtc gctcaagtaa
     3601 gtcaagaatg gtttgttgat gttctgatat gtgcacattt tcttgactca tattatagta
     3661 acggaagaca tagccttctt cattttccgc cactttaaag gctgttggac aaacttgcgg
     3721 tatgctgaga acagaatggc tcaagaggct accagtcgca accacgcttc cttcctgtct
     3781 agcaagctga aggctggtaa acggtgtctg caaggctttg gcacgacgga aagctgaaaa
     3841 gcgttcttgg gcttggtggc attcaagtgc aaactcgact tcaaactcac gcaagcattg
     3901 tgcttctggc gttgggaagt agccccagtc acctagctca cctgatgcac gcaaaatggt
     3961 cacggcaatg gtgttatccc caaggatttc gtattcattc aatcccttat tggatacagt
     4021 cacccctttt tcatcgtcat acagactgac aaaagcttgt tggtgttgag gattttcagg
     4081 attttcccat gaagcagctg gtttgtttgg tcgtgtcacc acctcataga tactttcaga
     4141 atcattgctt ggacgcgtgt tatgagtctt gaccaagaga cggatacggt gatccttggc
     4201 agtgttagta aagcgagtct tgaagcggat ttgtggattg tcaacaaaga caatcaactc
     4261 agtttccaga ggaatgtttg tcaattcttc tgaccgtcca gcctcacgct tcataaactc
     4321 gatgatacct tgttgctctt cttctagctt ttcatccgca ctgacaggca cggtcaattc
     4381 atgtttgagc aagattttag catagcgatc tgtgttttcc aagacctcgt ggcccttaag
     4441 ctctgcaaag attggctctg ttccttttgg ttggaaatag atatactcgt ttccgatgtc
     4501 cccacggtct tcgaagcgga taaagtcttc ataggcttcg tgagttgtct tgtcatatac
     4561 tgtgatattg tcatccacac tcaccgttac gaatggtgta tcaatcactc cgttttggta
     4621 aataccctca cggtgttctt gttttccttc cagcaattgg aaggttgtcc aagaaagcgg
     4681 cgctaggtga actggaatgg tcacgcgcac ttgtcgagca atacgagctt ggcggaactt
     4741 gtcttttggt aaatcgtact caaaattagc tccgaggtct tcgattgtag cctctacagg
     4801 acgaccatcc aagtcctcca cacggtaact tggtaagata agagcagcca tctttttgta
     4861 gccttctgtt gggtgcaatt ccttgaaatc acaagtcgcc acatcaatca ctgtgctgac
     4921 agtatcgacc ttatcatgca agcctgtgtt aatgacagta aagagatagt cactttgagc
     4981 cttatccgta gcaattttac ccttccactc gttgagcaag ttacttttaa caaagtttcc
     5041 tacttggttg accttggcaa aacgcgtttc catctcgcgg tgaacttcgt ccacgctaca
     5101 gccacagata ctatcatgtg gcgcattctg caaaagtgtt ttccaagcat aggtcaactg
     5161 gtccttgtgg ttgtgtccac cagtgataat agtcaagggt tctaccactt gctctaggag
     5221 gttgctattt tcttggaagg cttgttttag gtaaatgcgg gatgaagaag tgttggcaag
     5281 tgtgtaccag ccatctgttt cctgactggt caactcgcct gtaacagttg ataagtgttc
     5341 aggaagcgca ccttctacag cttgaacata ttcatcaaaa gaactatgaa caaagattac
     5401 atccgggaag agttcatttg ccacacgaat ggcttcgctc agatttttct gtacaggctg
     5461 gtggtcacag ccgttcatca tcaaccattg gttggtcgaa gcgtaggcac gcacatctga
     5521 caatttttgt ttccagaagg tcaaggcctc atctttgtca actgggattt cattcccatt
     5581 actgtaccag ttggcaaaga gaatacctaa aacacgacta ccatccacac cctgccagta
     5641 catttctgaa aactgggatg taaaccgctc atcttcaagg acttggttgt caaatccaat
     5701 cggcttcaca ccacgaccaa aggctgccac gtgaatacct gatttttgaa ggatttgagg
     5761 agcttgtccc atatttccaa aggtatctgg aaagtagcca atctgggttg atttacccca
     5821 tttggcagct tcttgttgac caatcaaggt attgcggaca ttggcttcac tggagatcaa
     5881 gtagtcatcc tgcaagatgt aaaagggacc aattttaagt ttgccctcgt caatgtagcg
     5941 ttggaccttg tcgcgatttt cagggcgaat ttgtaagtag tcatcaagga caatagtttg
     6001 tccatccaag tggaaactct tgaactcagg gtcattttca aagagatcaa agagattgtc
     6061 aaacaattcc accaactgca tacgatggct ttcaaaaggc aagtaccact cacgatccca
     6121 gtgactatgt gagataatat gtacaacaac attttccatg aagtaaaacc tcattctaaa
     6181 tttaaatttt aacgttttaa atgtaaactt gtgattctga taagaatcgg ttgagctaaa
     6241 gcgagcccct tagcggatat ccaagtaatc caagaccaac tcacagaaca tcatgttagc
     6301 ccaggagaac cattcacgag agtagagggt cggatcatct acgtggaagc tttcgtgcat
     6361 gacacctgta ccaccatcgc aggcaaccag ctgatccagc aagaattttt tctctgcctt
     6421 atctcttgtt gtcaatcctt ggatagaaag ggcgattggc cagatatagc gatagaaggt
     6481 atgagaactt ccgagaccgc tagcgtattc tccttggtag aagtatggat tttcagagct
     6541 cagaatggta cggcgagtgg cttgatacac ttcatcatcg atcgaacagt agcccagata
     6601 gggcgcagct agtagacttg gtacatttgg atcatccatg atgctggcat ttcctaggcc
     6661 atctacttca aaagcgtaaa tcttttcgcc cttgctgttg gtggtgtaag cgtagttttc
     6721 gattccttct tggatttcat cctgaagacg cttggcatca gcaataacac tctggctatc
     6781 agctaggttt aatgctgcga agatttcttg cacataaccc aagactacta cagcaaacat
     6841 atttgacgga atcaagtaac tatactggca acagtcatca ctcggacgaa aagctgacca
     6901 agtcatacct gtcactgcaa agtcaggtcc aaagccatca tttaccaagg tgtcttcctt
     6961 acggtccgta tctcggacaa aacgataagg agagttcttg tggtcttgtt caactgtcca
     7021 tagatggaga atttccttag tcgctgcgac aaaagtttca tcaaactgac tagtctcgcc
     7081 agtctctttc cagaggagat aagccaactg caaaggatag caaagcgaat ccacctcata
     7141 cttgcgctcc cagatccagc cgttaaggtc tgtgtggtca gtctcgtggt gccctttcca
     7201 gttctcctca atgttgaagg agttagcata gggatccttg agtaccaagg tcatctgacg
     7261 tttgaccaaa cctgcaatgg tctgacgcag gagggcatct cttttagcta catgaaggta
     7321 gggtctgagt tgggctgtcg aatctcgaag ccacatggca ggaatatccc cagtcaagac
     7381 aaaagttgaa ccatcttcta agatttcaac cgtattgtcc aaggtatcgg tgtagcaacg
     7441 ctcaaagaca tcaacccact ctggatggtc cttggcccgc tctgctactt catctagcca
     7501 ttctctaaca atttctttcg aataaatcat cgtgcaattc cctctttcaa acaagtttca
     7561 tgttcagtat atagcttttg agacagaaaa tacatacaca aatgatagtc atttttctac
     7621 aaaatagtta tctttaaaac tccttttcta aaggccctct ttttctgata taatgtagaa
     7681 aaacagctaa aggaaagact atgaaaccac tacttgaaac catcgatacc cgctttggta
     7741 ctgctagcaa gcatgccttc tctcggggaa ataccctgcc atacacaggc gtgccttttg
     7801 ggatgaatta ctttgtgccc cagaccagtg accaggatgg atcttggttt tttgatccgc
     7861 atctgcctat ctttcagggg attcgattaa ctcaccagcc cagtccttgg attggggact
     7921 actcttggct ccttctgaca cctgtcacca gtcaactggg gggagacagc ctctttcacc
     7981 gccagtcttc ttatgatata gataaagctt gcttccagcc tcactatttg aagctctttt
     8041 ctctgcgtta tcagattgaa acccagctca caccgacttg ctatggtgct tctattcgtt
     8101 tgaatcaaaa gcaaggcaaa gccctctccc tctatcttca cgcagcagat gaactgacag
     8161 tagagcaagt agataagcgg actcttgccc tgcgacaaga aggtaaaact gaaactaaca
     8221 aaaattcgct aacgatgttc actgccctgc aaatgaacac ggatattctt gctatcagcc
     8281 aagaagctgg ggactggcga attgacttag caagtagtca aaccgagatg caactagcca
     8341 cttctttcat ctctccttct caagctctaa tcaatctacc tcaagaagat tttgatagct
     8401 gtaaaacaag tgcccaagcg gattgggaaa atctcctcca tcgttttgac attatagaga
     8461 caggagaggc tgaccgaacc ttctttgacc actgcctcta cagactcttc ctcttcccac
     8521 agacttttta tgaggttgat gagtcaggga aagccatcca catggatctg gctactggta
     8581 ctgtcaagcc tggtgtcctc tttagcaaca atggtttctg ggataccttc cgcaccacct
     8641 tccccctctt tgcccttatc ataccggagc actatcaacg ctttttagaa ggtttcctca
     8701 atagctaccg cgatactggt ttccttccaa aatggctggc tccagatgaa cggggtatga
     8761 tgccaggtac actgctagat ggcattatcg cagatagcgc ctgtaaggac atggcccccg
     8821 acctagaagg agaactcttc caagccatgc tcgaaacagc cagcaaagcc gaccctctcg
     8881 gcatcaatgg ccgccacgga ctagcccaat accaagaact aggttacctc tctaccgacc
     8941 accacgaaag tgttagccat actctagact atgcctatag tgacttttgt atcgccagct
     9001 gtgccaaaaa actagagaac atagaaatcg ctgaaaccta caaggctgct tcacaaaatt
     9061 accgccagct atttgacgct gagacaggtt acatgcgagc acgagacaat caaggaaact
     9121 ttcaccctga cttctctcct tatagttggg ggcgagacta cgctgaatgc tctgccattc
     9181 aagctacttt aggcgttctc cacgacatcc ctggcttaat ccaactgatg ggtggaaaag
     9241 aaacctttag caactatctt ttgaaagcct gtcaagatgc tcccctcttt gaaacaacag
     9301 gctatggtta cgaaattcac gaaatgagcg agatggctac tgctcctttt ggacaaatag
     9361 ccatttccaa ccagcctagt ttccacattc cttatctctt ccgctacagc gattaccctg
     9421 actacactgc ccttcttatc aagacgctcc gtcagaaagc ttttcaccca agttgggaag
     9481 cctatcctgg agatgaagac aatggtagtc tctctgcttg gtacatctgg tcagctctcg
     9541 gattttatcc aacctgtcca ggaaaaccaa gctatgatct cggaatccct ctctttgacc
     9601 atctacgagt ctacctagct aaagaaaata aatggctaga tattcatact gagcaaaacc
     9661 acagccattt taactttgtc aaagaatgcc gactggacaa aacactcgta tcaactattc
     9721 aacaccaaga cctcctaaaa gctgaacaac taactttcac cctcagctgg ctaccaaatc
     9781 actaataacc aaaagaacct ttgcatcgcg caaaggttct tcttttatga aacttggact
     9841 tgaagttgat ccacaagctg accatccacc gttaggttca gatagaaatc caaggtttta
     9901 tctcctgcga aatacaaggt tggtagcgtc agcctttttt cagtctcacc agcttgaaac
     9961 gcaaggacat aaatctcgtc ctgataggcg acaccatgga cacctgtccc cggttgaatc
    10021 gaaatcttag cctctaaaga ggagctactt tcactacgtt caatcctaaa atgaagagtc
    10081 tctccctttg ccacagctag gcttttttct gcaaatgcta gttcctgaac aacttctttt
    10141 tttgataacc caggagtttt ataaagggaa atcttggtca atacagggat agattgtgcc
    10201 tcggtaatca tcacgcgcac cttttgtgcc tctactagcg gacctcgcaa gaggcgctta
    10261 tgaccaactg tgaagcccct gccaaactcc tgccagacac catccacctc tacttgcaca
    10321 tgaaaagcag cgattcgttg ccctagcttc aaatcttctc ttaactcaat tacatcaaaa
    10381 gttttaggag aacctaaatc gagttctaac tggatgggca agtctgcatc gcttgcccaa
    10441 gagctggtct caaggccgtc tgtcaaatgg cgacaatcaa agtctgcgga aagagctgga
    10501 ccagatacct cagctcccag agccaaatct tctttataga gctcattgcg ataggtcgca
    10561 aattcataaa gtcgttcaat atcctttgca tcaaagagcc cagcttgatt cggcggaata
    10621 ttaagcaaga gtggagttcc tcgccctact gagtgaaagt agatttcgac caactcctcg
    10681 agagacttag gatcctgatc ctcatggtag aaccagcctg gacggatgga aacatctgcc
    10741 tctccgattg aaaaaatcgt gcccgaggga tccccgtgct gaagatagtt cagctctgct
    10801 tctgttccta gtttatcaag attcaccttt tgccacagtg gatcacctgc ataccctcgt
    10861 tcattgccaa tccagcggat actggtgcct tctgttgaaa aaatcaagca atcgccctgc
    10921 aggtcacgaa tggtttcaaa ccatttttca aattcataat taaccttttg cgcgccctct
    10981 cctctggcac catccatcca aacctcagcg aacttaccag cattcccata gttaggattt
    11041 gataagattt ccttcaactg agccagataa taggcattgt agtccgcttc tcggtccaca
    11101 tgatagaggg gactatgggc atcccacggt gacaggtaga cccccatatc catatcaaac
    11161 tctgtggcag cttgggatac ttcaaggagc aagtcgccct ttcctctcct ccaaggactg
    11221 accttaaccg aataatctgt gtgagctgtc ggataaagga caaagccatc gtggtgcttg
    11281 accaccaaaa tcaacttttt gaagcccgtt tccttgagca cacgaaccca ctcacgcgca
    11341 tccaactgac tcgggttaaa gcgctcagga tcctcctgtc cagtccccca ttcttggtca
    11401 taaaaggtat taggaccgaa gtggataaaa gctgctagtt catctcccag ataagctagc
    11461 tgagtctgac ttggtaacgg tccatgcggt ttgattttct tcatcgttat atatctcctt
    11521 cttttgcaac ttctcttgtt cacaaggtta tccacaggtt gtggataata aaccatgatc
    11581 taacagccag ctctttccaa ctccaactgg taggctcagg atttttctcc tcaatgttcc
    11641 ctcttcaaac agctctgtca tatggttctg ctaacacctc tcagaatgct actctccata
    11701 attattctca ggcttctttc aggtcattgt gtgaagacca ttcactctcc agacttttcc
    11761 acagattgtg aataagtgat tattctaagc tatcacctcg tcgactataa caaaaaataa
    11821 aaagagggtc aataagataa ttatctcttc ctaaatactc agaaaagatt ctataatttg
    11881 tacaattgaa caagaaatgc ttctccaaaa tctatcttca aaagaatgtt gcatcttttt
    11941 atcctttcac acaaacattt ctctttatac agatccaagt gataaccaga tgataattgg
    12001 acactttttg gtcatttgta tattttttga aaaatttttt aaaaaaattt tatatccttt
    12061 ttatagaagt ttatgcattt gtatctatgt attctatcct atgttatgta taataacata
    12121 aaattgtgct aaacatcata atttatatta ttttccgaga aattatagcc attgacatta
    12181 cctaggaatt gcgttataac atacatgtaa gcggtaccca aaatggtgcc aagtcaaaat
    12241 ttttaaggag gaaaatacat gtcttctcat ccaattcagg tcttctcaga aattgggaaa
    12301 ctgaaaaaag ttatgttgca ccgtccaggc aaggagttag aaaacttgtt gccggactat
    12361 cttgaaaggc ttctttttga tgatattcct ttcttggaag atgctcaaaa agaacatgat
    12421 gcatttgccc aagctcttcg cgatgaagga attgaggttc tctacctaga acaactcgct
    12481 gctgaatcat tgacctctcc agaaatccgc gatcaattta tcgaggaata cttagacgaa
    12541 gccaacatcc gtgatcgtca aaccaaggtt gctattcgtg aattacttca cggcatcaag
    12601 gacaaccaag aattggttga aaaaacaatg gctgggattc aaaaagttga attgccagaa
    12661 attcctgacg aagctaaaga tctaactgac ttagttgaat cagattatcc atttgcaatt
    12721 gacccgatgc caaacctcta tttcactcgc gacccatttg caacaattgg aaacgccgta
    12781 tcgcttaacc acatgtttgc agatactcgt aaccgtgaaa cactctacgg taagtatatc
    12841 ttcaaatacc acccaatcta tggcggaaaa gtggatttgg tctacaaccg tgaagaagat
    12901 acgcgtatcg aaggtggaga cgagctaatt ctttctaaag acgtccttgc agtaggtatc
    12961 tctcaacgta cagacgcagc ttctatcgaa aaacttttgg tcaacatctt caagaaaaat
    13021 gttggcttca agaaagtttt ggcctttgaa tttgctaaca accgtaaatt catgcacttg
    13081 gatactgtct tcactatggt agactatgac aagttcacta ttcacccaga aatcgaaggc
    13141 aaccttcacg tttactcagt tacttacgaa aacgaaaaac ttaaaattgt tgaagagaaa
    13201 ggtgacttag ctgaacttct tgctcaaaac cttggtgtag aaaaagttca tttgattcgt
    13261 tgcggtggtg gcaatatcgt agcagctgcg cgtgaacaat ggaacgacgg ttctaacact
    13321 ttgaccatcg cacctggtgt ggtagttgtt tatgaccgca ataccgtgac caataagatt
    13381 ttggaagaat acgggcttcg cttgattaag attcgcggaa gtgaattggt tcggggccgt
    13441 ggtggacctc gttgtatgtc tatgccattt gaacgtgaag aagtgtaatc gctgttcggt
    13501 attcgtcaat agaaaatgta aaaaatagaa agaggaaata ataaaatgac aaattcagta
    13561 ttccaaggac gcagcttctt agcagaaaaa gactttaccc gtgcagagtt agaatacctt
    13621 attggtcttt cagctcactt gaaagatttg aaaaaacgca atattcaaca ccactacctt
    13681 gctggcaaga atatcgctct cctatttgaa aaaacatcta ctcgtactcg tgcagccttt
    13741 acaactgcgg ctatcgacct tggtgctcac ccagaatacc tcggagcaaa tgatattcag
    13801 ttgggtaaaa aagaatctac tgaagatact gctaaagtat tgggacgtat gtttgacggg
    13861 attgaattcc gcggattcag ccaacgtatg gttgaagaat tggcagaatt ctcaggcgtt
    13921 ccagtatgga acggtctaac tgacgaatgg cacccaactc aaatgctcgc tgactacttg
    13981 actgttcaag aaaacttcgg tcgcttggaa ggcttgacat tggtatactg tggtgatgga
    14041 cgtaacaacg ttgccaacag cttgctcgta acaggtgcta tccttggtgt caatgttcac
    14101 atcttctcac caaaagaact cttcccagaa aaagaaatcg ttgaattggc agaaggattt
    14161 gctaaagaaa gtggcgcaca tgttctcatc actgaagatg ctgatgaagc agttaaagat
    14221 gcagacgttc tttacacaga cgtttgggta tcaatgggtg aagaagacaa attcgcagaa
    14281 cgtgtagctc ttcttaaacc ttaccaagtc aatatggact tagttaaaaa agcaggcaat
    14341 gaaaacttga tcttcctaca ctgcttgcca gcattccacg atactcacac tgtttatggt
    14401 aaagacgttg ctgaaaaatt tggtgtagaa gaaatggaag taacagacga agtcttccgc
    14461 agcaagtacg ctcgccactt cgatcaagca gaaaaccgta tgcacactat caaagctgtt
    14521 atggctgcta cacttggtaa cctttatatt cctaaagtat aattttagat aataaaccgt
    14581 ctaccaacag ctatgagggc tgcgactaat agctttagtc cggtcctctt ttatgtaatg
    14641 gtaatctatt atttcttata aaatatgtga aaaatcatta aattgaaatc taaacgcatt
    14701 ctattgagtg tgataaagga gaatttatgg caaatcgtaa aattgtagta gctttgggag
    14761 gaaatgcgat tctttcttct gacccatcag caaaggctca acaagaagct ttagttgaaa
    14821 cagctaagca tcttgtaaaa ttgattaaaa atggagatga tttgattatc actcacggta
    14881 atggacctca agttgggaat ctcttgctcc aacatttggc atcagactct gaaaagaacc
    14941 ctgccttccc actcgactca cttgtcgcta tgacagaagg tagcatcggt ttctggttga
    15001 aaaatgcttt gcaaaatgct ctcttggatg aaggcatcga aaaaaatgtt gcctctgttg
    15061 taacgcaagt tatcgtagat aaaaatgatc cagcttttgt taacttgagt aaaccaatcg
    15121 gtcctttcta ttcagaagaa gaagcaaaag cagaagccga aaagagcgga gcgactttca
    15181 aggaagatgc tggccgtggc tggcgtaagg tcgttgcctc accaaaacct gttgacatca
    15241 aagaaattga aaccatccgt actcttttaa ataatggtca agtcgtcgta gctgcaggtg
    15301 gtggcggtat tcccgtcgtc aaagaaaaca atggacattt gactggtgtc gaagcggtta
    15361 ttgataaaga cttcgcttcc caacgtttgg cagaattggt tgatgcagac ctcttcatcg
    15421 ttttgacagg tgtagattat gtatttgtta actacaacaa gccaaaccag gaaaaattgg
    15481 aacatgtgaa tgttgcccag ctggaagaat atatcaaaca agatcagttt gcaccaggta
    15541 gcatgcttcc aaaagtagaa gcagctatcg cttttgtcaa tggtcgtcca gaaggaaaag
    15601 cagttattac ttcccttgaa aatctaggcg ccttgattga atctgaaagc ggaacaatta
    15661 ttgaaaaagg ataagttgtt ttactaataa gatgtattct atttctagta tctttatatc
    15721 aaattagaaa ttattcttga aaacatgtac aatatttcaa aagatactag ttttagactt
    15781 taatatggta aaacaaatat aaatagaaag cgttttcttg aatgtttatt taagaaagta
    15841 gttggttttt tacactttgt tagacatcag gaggaaaaac aaatgagtga aaaagctaaa
    15901 aaagggttta agatgccttc atcttacacc gtattattga taatcattgc tattatggcc
    15961 gtgctaactt ggtttatccc tgcgggggcc tttatagaag gtatttacga ggctcagcct
    16021 caaaatccac aagggatttg ggatgtcctc atggcaccga ttcgggctat gctaggtact
    16081 catccagagg aaggttcgct cattaaagaa acgagcgcag cgattgatgt agccttcttc
    16141 atccttatgg ttggtggttt ccttggcatt gtcaacaaaa ctggtgctct tgacgtaggg
    16201 attgcctcta tcgtgaagaa gtataagggc cgcgaaaaaa tgttaatttt ggtattgatg
    16261 cctttgtttg ccctcggtgg tacaacttat ggtatgggtg aagaaacaat ggccttctat
    16321 ccactccttg tgccagttat gatggccgtt ggttttgata gcctgactgg tgttgcaatt
    16381 attttgctcg gttctcaaat cggctgtttg gcatctactc tgaatccatt tgcgacaggt
    16441 attgcttcag cgactgcggg agttggtaca ggggacggta tcgtacttcg tctgatcttc
    16501 tgggttacct tgactgctct tagtacttgg tttgtttacc gttatgcgga taagattcaa
    16561 aaagatccga ctaagtcact ggtttatagt actcgcaaag aagatttgaa acactttaac
    16621 gtagaagaat cttcatctgt agaatctaca cttagcagca aacaaaaatc agttctcttc
    16681 ttatttgtgt tgacattcat cttgatggta ttgagcttca ttccatggac agaccttggc
    16741 gttaccattt ttgatgactt taatacttgg ttgactggtc ttccagttat tggtaatatt
    16801 gtcggttcat ctacttctgc actaggtact tggtacttcc cagaaggcgc aatgctcttt
    16861 gcctttatgg gtatcctgat tggtgttatt tatggtctta aagaagataa gattatctct
    16921 tccttcatga atggtgctgc tgacttgctc agtgttgcct tgatcgtagc gattgctcgt
    16981 ggtattcaag ttatcatgaa cgacggtatg attaccgata caatcctcaa ctggggtaaa
    17041 gaaggcttga gcggtctatc ttcacaagtc tttatcgttg taacttatat cttctatcta
    17101 cctatgtcat tcttgatccc atcttcatct ggtcttgcca gcgcaactat gggtatcatg
    17161 gctccacttg gagaatttgt aaatgtccgt cctagcttga ttatcactgc ttaccaatct
    17221 gcttcaggtg tcttgaactt gattgcacca acatctggta ttgtgatggg agctcttgca
    17281 cttggacgta tcaacattgg tacttggtgg aaattcatgg gcaaactcgt agtcgctatt
    17341 attgtagtga ccatcgccct tcttctcctt ggaaccttcc ttccattcct ataaaatagt
    17401 gagtgaggtg attccatgaa aatagatata acaaatcaag ttaaagatga atttcttata
    17461 tcattaaaaa ccttgatttc ctatccttca gtactcaatg aaggagaaaa tggaacacct
    17521 tttggacaag caatccaaga tgtcctagaa aaaactttag agatttgtcg agacataggt
    17581 ttcactacct atcttgaccc taaaggttat tacggatatg cagaaatcgg tcagggagca
    17641 gagcttctgg ccattctctg tcatttggat gttgttccat caggtgatga agcagattgg
    17701 cagacaccgc catttgaagc aactatcaaa gacggctggg tattcggacg tggtgtccaa
    17761 gatgataaag gcccttcgct cgcagctctc tatgcagtaa aaagcttgct ggaccaaggt
    17821 attcagttca aaaagcgcgt acgctttatc tttggtaccg atgaggaaac cctctggcgc
    17881 tgcatggcac gctacaatac catcgaagaa caggccagta tgggctttgc acctgactca
    17941 tcttttcctc tgacctatgc tgaaaaaggg cttctacagg tcaaacttca tggccctgga
    18001 tcggatcaac tagagcttga agtaggaggc gcctttaacg ttgtaccaga caaggccaac
    18061 taccaaggtc ccctctatga acaggtttgt aacggtctca aagaagctgg ttatgattac
    18121 caatccactg aacaaaccgt aacggttctc ggagtgccaa agcatgctaa ggatgctagt
    18181 caaggtatca atgctgtcat ccgactagct accattcttg ctcctctcca agaacaccct
    18241 gctctcagtt ttcttgcaac acaagcaggt caagacggca caggaagaca aatctttggt
    18301 gatatagcag atgaaccttc tggtcaccta tcctttaatg tcgcaggtct catgatcaat
    18361 catgaacgtt ctgaaatccg tattgacatt cggactcctg tcttagctga caaggaagaa
    18421 ctagtagagt tgcttacaag atgtgcacaa aactaccaac tccgctacga agagtttgac
    18481 tatctagcgc ctctatacgt cgcagaagac agtaaactcg ttagcacact gatgcaaatc
    18541 taccaagaaa agactggcga taacagtcct gctatttcat ccggtggtgc cacttttgct
    18601 cgcaccatgc caaattgtgt agccttcggc gccttattcc caggagcgaa gcagacagaa
    18661 catcaggcaa atgaatgtgc cgttctagaa gatttgtacc gtgctatgga tatttatgcc
    18721 gaagccgtct atcgacttgc aacttaatca ggcaactgtt tctaccaaaa aaaatcgacc
    18781 gattaatgaa ctgcacccca aaagttagac agaataaatc taacttttgg ggtgttttat
    18841 tatgaaattg agttatgaag ataaagttca gatctatgaa ctaagaaagc aaggacaaag
    18901 cttcaaacag ctttcaaaaa gatttggtgt ggatgtttct ggtctaaagt catctgaatc
    18961 tttgagatga gctttataaa tcgctttttt cagtttttgc actggtgttt cgataaactc
    19021 aaacttttta gccgtggtat tgcctgattt tatagtatat tgaaactaga atagtacacc
    19081 tctacttcta aaacattttt agaaatcgat ttgactgtcc tgaacgattt gtcctgttct
    19141 tatttcattt tactatattt gagccacttc gtctttaacg gctttattca taagctcttg
    19201 taatttttct ttactatcaa ttacttctga ttttccgttg taatttattg taataggttt
    19261 taacttacct aatttctcga cacgctcatt aatttgatct tttttgaagg ctgcatatgt
    19321 ttttcctaag attttttcga aaatatattt atcagatagc ggtttgcctt cttcttcagc
    19381 ttggtttttg tattgatttg aaacataagg aacaaatcct tcatagtaac ctaatgctcc
    19441 cataagttca aaagcttgtt ttctaattca aaccattgca actcagattt cagcttttca
    19501 gataaatcct gctcatccaa ataatgactt gaaattagtg ctgaactcgt ttctgtatcc
    19561 tgtacaggct gatcacccat accagcaaaa aataaactcg ttcctagcaa gaccgaacaa
    19621 gctcctattg catatttcct caaagaaaaa cgctgctttc tctcaaattg aaattctttc
    19681 atcccatctc ccatcattca ttattactgt atattttgta tatcagaaat agtttgtatt
    19741 cacaaatctt tctagttatt cccttatcat tcctaattaa gggaggtaac atacaataat
    19801 ttttagttaa atgtatatct atgttttttg tttttcttaa taaacgcaat acaaaaagag
    19861 cctgttgcca agctctttgt actcaatgaa aatcaaatag caaactagga aactagccac
    19921 aggttgctca aaacaccgtt ttgaggtagt agataagact gacgaagtca gctcaaaaca
    19981 ctgttttgag gttgcagata gaactgacaa agtcagtaac atctatacgg caaggcgacg
    20041 ctgacgtggt ttgaagagat tttcgaagag tattagtcta ttatttcttc tcagcgcgaa
    20101 gggctgacaa gatttgtgtt cggatatcat ccacaccatt tggcgtattt ggtaaaaaga
    20161 tggtttgatt tcctttagag gcaaaggtat tcaaggtatc caaatactgg ttggtcaaga
    20221 ggatagacat gatttgttct tctgtcatgc caacattggc ttccttgagt tcggtgatag
    20281 actctgccaa tccatccaca atcgccttac gttgttgggc aatccccaca ccatgaaggc
    20341 ggtctttttc tgcttctgct tcagctgcag tgacaatttt aatcttgtca gcttccgcca
    20401 attcttgtgc tgcgacccgc ttacgttgcg ccgcattgat ttcattcatg gattgcttaa
    20461 cttctgcatc cggttcgact ttggtaatca aggttttcac gataatgtag ccgtaagtgg
    20521 tcatttcttc tgctacttgg tgttgaactt caagggcaat ctcatctttt ttctcaaaca
    20581 attcatccaa ggttaatttt ggaacagaag agcgaagagc atcttcgata taagatttaa
    20641 tctgagattc tggacgtatg agtttatagt aagcatctgt cacgctctgc tcgttgacac
    20701 ggtactgagt cgctacattc atcataacga acacattgtc cttggtctta gtctcaacca
    20761 caatatcact ttgcaacaag cgcaactgaa tccgtgctgc aatcgagtca atcccaaaag
    20821 gcaagcgaat atgaataccg ctattagcaa ccttttggta tttcccaaag cgttcaataa
    20881 tcgccaccga ctgctgacga accacataaa ctgtactcag tgtgactatc accaatagga
    20941 gcacacaaac aatcagaaaa atcatgaaaa atattgccat aatggaacct ccacaagtat
    21001 ttttctagta ttatagcaca tttaaagaag gctgtgccgt ttttactgcg atttttcctg
    21061 aaatgtcaat aattagaggt gaattgtcct attgtcgtcc aatctcttgc taaaataact
    21121 ctttataaaa ggcaatcgtt tcttctaagg ttggcataaa tggatttcct ggtgcgcagg
    21181 catcaatcaa ggcattctta gaaaggtatt caaagtcgaa atctttttct tcaataccaa
    21241 gttcagtcag tttcttagga atacctactg tctcagaaag cttctcaatc tcaacaatcg
    21301 cataatcggc acattcttga tctgatttac cttctacatg aagtcccaag gctttggcaa
    21361 cattgcggaa agcttctggt acacgtttag cattttcatg ttctataact ggtagcaaca
    21421 tggcacagca aacaccatgt ggcaaattat atactgcacc gagttggtga gccattgagt
    21481 gaacataacc aagaccagca ttattaaagc tcataccacc aaggaagatg gcattgacca
    21541 taccttcacg cgcttcaata tcatgtccat tttctacagc acgaggaaga tattccttga
    21601 taagctcaat agcaccaata gacagtttct tggttacatc ataagcacca ggtgttacca
    21661 aagcttcaac agcgtgagtc agagcatcca taccagtagc agcagtcaag gcttgaggtt
    21721 tggaaagcat gagttcaggg tcattgacag aaatcaaggc aaggctattc ttgtcaacca
    21781 ttaccatctt aaccttgcgt tcttcatcag taatcacata gttaatagtg atttctgctg
    21841 atgtacctgc cgttgtattg atagccacaa ccggcaagcc ttttttagca gacttatgaa
    21901 gcccttcata atcctgtggt tttccaccat ttgtagccat gatagaaata caactagctg
    21961 catcctgtgg agaacccccg ccaagactga tgataaaatc acatctatgt tcttgcaaag
    22021 cagctacccc atctgtgaca tttttacaag tagggtttgg ctctacatcg ctaaagatga
    22081 catattcgat tccttctgta tccagtggtt ttaaagtctt aggtaaaata tcactgcctt
    22141 cgatgtactt atctgtcacc aaaagtgcct ttttatagcc aagttccttg atataaggac
    22201 ccacttcatt tacaacacct tttccaataa ggttgactgc cggaacataa aatatagcca
    22261 tataattttc ctcctgcgcc tccgcgctat ctatttaaca tcattatatt actttttgta
    22321 ttcgttttca attatttgtg aattgtttaa caaatctttt taaaaggata ggagggacgt
    22381 aagttcacct cctatataaa caagttttat ttatgtagtg gtcccaacaa ctgacatgca
    22441 cgatagtctg ctgattctag atcttctgtt ccaaataagg accaattttt aggtctaaag
    22501 atatcttcct caggtacatt atgcatattg acaggaattc tcaacataga agccaaggta
    22561 atcaagtctg ctccaatgtg tccatatgtt atggctccgt gattagctcc ccaattattc
    22621 atgacgtcat agacagactt gaaagcacct tttcctgtca aacgtggagc aaaccaagta
    22681 gttggccatc ctgaatctgt acgattatct aaagtatggt gaacatcttc aggaagttca
    22741 agtgtgtaac cttctgcaat ttgtagcact ggaccaaccc cttttagaag attgagacgt
    22801 accattgtta ctggcatatc ccccttcgtc aagaaacgag ttgagaatcc tcctccacgg
    22861 aagtactcgc ggtttgctgg tgggaagtct gtattttcaa gcatagcctg tacttcactt
    22921 tcttccaact cccagaatgg tttcataaca ggtttgccat ctcgagtagc ttgacctgta
    22981 ccatccaatg tacaagaacc agagttgatt agatgtaaga agccagctgc agcacaaccc
    23041 tctaaagtat gtcccgttac acgtttaaca gcctctggac tccaataagt gcgcacatca
    23101 gcaaagattt gtggagtatt tgttaataga taattaaaga gcatagacac accatttagt
    23161 gaatcattct ctgtcgcaaa tacaaatggt tttcgaatac cattccagtc aaactgagta
    23221 ttgaggaaag tttccataaa atctccattt ggaaaatggt ctgtccactg acgttgacct
    23281 tggaaaccag ctactaaagc atggtgacca accgcttctt cctcaaaacc aagttcagca
    23341 agccttgggt taccaaccat taagtcacgt ccaatcatga acatcttaat aacaaattcc
    23401 cattgttttt ctttctcttc tttagaaaga atcaaatcct cacgatttcg gtcaacccct
    23461 tctttgatat gttcttttac ccaaaccata gcacgttcga actcttctgg gtcataaata
    23521 ccacggtcca tacggcgcgt gaactccgtc atatctaccg attcatttcg cattcctaag
    23581 tattcttgga agaaatctgg atttacaata gaaccgccaa tccccatcga aacactaccc
    23641 attgataggt aagcagtgtc tctcatcaag ccagttgcaa gagctgcacg cgcataacgt
    23701 aaaagttttt ctttgacatc ttctggaata tctgtatcat tagcttcctg aacatctcta
    23761 ccataaatcc caaaggctgg aatccctttt tgagcatgtg aagctagtac agctgcaaga
    23821 tagacagctc ctgggcgttc tgtcccatta aatccccaaa tagcatgagg aatatctgga
    23881 gacatatcca tagtttcact accataacac cagcatggtg taactgtaat tgttgcgcaa
    23941 acatttgatt ttttaaacaa ctcatgggaa gctgcagcct ctggaacacg accaatggta
    24001 gatggagaaa tcacacattc cacaggttcc ccatctggat atttcaatgt gcttgaaatc
    24061 aaatctgcca cacttttagc catgttcatt gtttgtactt caagtgattc gcgtacacct
    24121 tgacgacgac catcaatagt cggacgaatc ccaatacgtg gatgttgaat catactattt
    24181 tcctcttatt tttctgtttc tttcatacta ccgatgataa tttttaaaat tacttataag
    24241 tataaacctc tacctctgcc aaacttaaag gaattcctgc gtttctcaaa gaaattctaa
    24301 ccttttttcc cttcagccct tttaagtcta tggatagatt attgctttct aaactgtcaa
    24361 tatgttgttt aaaaacttca tgattatttg aatcatatat aataatatca aaatttgata
    24421 atctctgaat ttcagcatct gttctattat aaataattaa cttttctaat tcttcggttt
    24481 gtgctaaatc tatctcccac catgaaggag aatctccttt ggtatgagtc actgaatgat
    24541 gaccataatc tccgttttta tttccatcaa ctgctagacg agaaaaacca ttgtaatccg
    24601 ttgaactctg tcgagtttct ttggttaatg caatattaga aagtttcttc ggagttctct
    24661 ttgaaccata ggcttcaact tccgctaaac ttaacggaat agctgctgat tttaattcta
    24721 ttttgactag cttagcccct acagaaggta cttttaaaga taacaaacca tcaactactt
    24781 tatcaaaatg tcttctaaaa acttcttctc ctgatgaaga tagaaaaata acatcaaaat
    24841 tagataaacg ctgaggttcg gcatctgttc tattataaat atcaacttta gaaaccgtaa
    24901 actcttctcc cagatcgacc tgccaccaag cgttagaatc tgccttagta tgagtcaccg
    24961 aatgatgtcc gtaatctcca tctttattac catcaactgc taaagcagct acaccctcat
    25021 aattggttga actttgagta gctaccttat ttgtagagac tactttatct tctgttattt
    25081 tatctatatc ctcttcagat tgcttaccat ctgattctct aaaaacctct acttctgcta
    25141 aactcaaagg cactccactc gttagtaatt taactttaat ataccttgct cctttttctt
    25201 tgaaatctag actaacagat tcacccgaca aattattaac atgtttctta gcaacttcgt
    25261 ttctattatt gtcatataga atcacatcaa aattagatag acgttgagtc tcagcatctg
    25321 tgcgattata aattttaaca agcccaactt tatccatttt tttcaaatcg acttcccacc
    25381 aagagggatt atctgcccta gtgtgtgtta ccgaaccaga gttaaaatta ccatttctgt
    25441 taccatccac agctctatta gggtctccat tgtaatctac agaactttgt gttgttggtt
    25501 ttgcatatgc tatattcaaa ttaccatcat taaatttatc tggtgttggg aaagggactg
    25561 ggcctgtccc ttcagtattt atagacatct ctaccattcc attatgatta accgtaatgg
    25621 tataaacatg ggtattctca tcccaatttt ctgtataagt ataatgattt ttatcgccac
    25681 ttatatttat ctgaggttta tgaccagtat gcccttttaa tgtaagtgtt gttgtcctaa
    25741 agtcattatc tacaggattg atggaataat ttttgcttat ccagttcgct aactctaatt
    25801 cttctttctt ccaacttttt gatgcatcaa aatttcctga taatgcccac atagctgtct
    25861 tatctgtcct gtaatt
//
LOCUS       DAVBDR010000026        24327 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.026, whole genome shotgun sequence.
ACCESSION   DAVBDR010000026 DAVBDR010000000
VERSION     DAVBDR010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 24327)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24327)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24327
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.026"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            complement(<1..618)
                     /locus_tag="VQ540_001102"
     CDS             complement(<1..618)
                     /locus_tag="VQ540_001102"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HET2544916.1"
                     /translation="MNLLIMGLPGAGKGTQAAKIVEQFHVAHISTGDMFRAAMANQTE
                     MGVLAKSYIDKGELVPDEVTNGIVKERLSQDDIKETGFLLDGYPRTIEQAHALDKTLA
                     ELGIELEGIINIEVNPDSLLERLSGRIIHRVTGETFHKVFNPPVDYKEEDYYQREDDK
                     PETVKRRLDVNIAQGEPIIAHYRAKGLVHDIEGNQDINDVFSDIEK"
     gene            complement(769..2079)
                     /gene="secY"
                     /locus_tag="VQ540_001103"
     CDS             complement(769..2079)
                     /gene="secY"
                     /locus_tag="VQ540_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HET2544917.1"
                     /translation="MFFKLLREALKVKQVRSKILFTIFIVLVFRIGTSITVPGVNANS
                     LNALSGLSFLNMLSLVSGNALKNFSIFALGVSPYITASIVVQLLQMDILPKFVEWGKQ
                     GEVGRRKLNQATRYIALVLAFVQSIGITAGFNTLAGAQLIKTALTPQVFLTIGIILTA
                     GSMIVTWLGEQITDKGYGNGVSMIIFAGIVSSIPEMIQGIYVDYFVNVPSSRITSSII
                     FVIILIITVLLIIYFTTYVQQAEYKIPIQYTKVAQGAPSSSYLPLKVNPAGVIPVIFA
                     SSITAAPAAILQFLSATGHDWAWVRVAQEMLATTSPTGIAMYALLIILFTFFYTFVQI
                     NPEKAAESLQKSGAYIHGVRPGKGTEEYMSKLLRRLATVGSLFLGVISILPIAAKDVF
                     GLSDVVAFGGTSLLIIISTGIEGIKQLEGYLLKRKYVGFMDRTE"
     gene            complement(2092..2532)
                     /gene="rplO"
                     /locus_tag="VQ540_001104"
     CDS             complement(2092..2532)
                     /gene="rplO"
                     /locus_tag="VQ540_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004225266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HET2544918.1"
                     /translation="MKLHELKPAEGSRKVRNRVGRGTSSGNGKTSGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNINAKEYAIVNLDQLNVFEDGAEVTPVVLIEAGIV
                     KAEKSGIKILGNGELTKKLTVKAAKFSKSAEEAITAKGGSVEVI"
     gene            complement(2677..2901)
                     /gene="rpmD"
                     /locus_tag="VQ540_001105"
     CDS             complement(2677..2901)
                     /gene="rpmD"
                     /locus_tag="VQ540_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012386624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HET2544919.1"
                     /translation="MVFQFLIWHKKGDKMAQIKITLTKSPIGRIPSQRKTVVALGLGK
                     LNSSVIKEDNAAIRGMITAVSHLVTVEEVN"
     gene            complement(2873..3367)
                     /gene="rpsE"
                     /locus_tag="VQ540_001106"
     CDS             complement(2873..3367)
                     /gene="rpsE"
                     /locus_tag="VQ540_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HET2544920.1"
                     /translation="MAFKDNAVELEERVVAVNRVTKVVKGGRRLRFAALVVVGDHNGR
                     VGFGTGKAQEVPEAIRKAVDDAKKNLIEVPMVGTTIPHEVLSEFGGAKVLLKPAVEGS
                     GVAAGGAVRAVVELAGVADITSKSLGSNTPINIVRATVEGLKQLKRAEEIAALRGISV
                     SDLA"
     gene            complement(3385..3741)
                     /gene="rplR"
                     /locus_tag="VQ540_001107"
     CDS             complement(3385..3741)
                     /gene="rplR"
                     /locus_tag="VQ540_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HET2544921.1"
                     /translation="MISKPDKNKLRQKRHRRVRGKLSGTADRPRLNVFRSNTGIYAQV
                     IDDVAGVTLASASTLDKEVSKGTKTEQAVAVGKLVAERANAKGISEVVFDRGGYLYHG
                     RVKALADAARENGLKF"
     gene            complement(3825..4361)
                     /gene="rplF"
                     /locus_tag="VQ540_001108"
     CDS             complement(3825..4361)
                     /gene="rplF"
                     /locus_tag="VQ540_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HET2544922.1"
                     /translation="MSRIGNKVIVLPAGVELANNDNVVTVKGPKGELTREFSKDIEIR
                     VEGTEITLHRPNDSKEMKTIHGTTRALLNNMVVGVSEGFKKELEMRGVGYRAQLQGSK
                     LVLAVGKSHPDEVEAPEGITFELPNPTTIVVSGISKEVVGQTAAYVRSLRSPEPYKGK
                     GIRYVGEFVRRKEGKTGK"
     gene            complement(4553..4951)
                     /gene="rpsH"
                     /locus_tag="VQ540_001109"
     CDS             complement(4553..4951)
                     /gene="rpsH"
                     /locus_tag="VQ540_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009754342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HET2544923.1"
                     /translation="MVMTDPIADFLTRIRNANQAKHEVLEVPASNIKKGIAEILKREG
                     FVKNVEIIEDDKQGVIRVFLKYGPNGEKVITNLKRVSKPGLRVYKKREDLPKVLNGLG
                     IAILSTSEGLLTDKEARQKNVGGEVIAYVW"
     gene            complement(5236..5505)
                     /gene="rpsN"
                     /locus_tag="VQ540_001110"
     CDS             complement(5236..5505)
                     /gene="rpsN"
                     /locus_tag="VQ540_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HET2544924.1"
                     /translation="MAKKSMVAREAKRQKIVDRYAEKRAALKAAGDYEGLSKLPRNAS
                     PTRLHNRCRVTGRPHSVYRKFGLSRIAFRELAHKGQIPGVTKASW"
     gene            complement(5523..6065)
                     /gene="rplE"
                     /locus_tag="VQ540_001111"
     CDS             complement(5523..6065)
                     /gene="rplE"
                     /locus_tag="VQ540_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HET2544925.1"
                     /translation="MANRLKEKYLNEVVPALTEQFNYSSVMAVPKVDKIVLNMGVGEA
                     VSNAKSLEKAAEELALISGQKPLITKAKKSIAGFRLREGVAIGAKVTLRGERMYEFLD
                     KLVSVSLPRVRDFHGVPTKSFDGRGNYTLGVKEQLIFPEINFDDVDKTRGLDIVIVTT
                     ANTDEESRALLTGLGMPFAK"
     gene            complement(6089..6394)
                     /gene="rplX"
                     /locus_tag="VQ540_001112"
     CDS             complement(6089..6394)
                     /gene="rplX"
                     /locus_tag="VQ540_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HET2544926.1"
                     /translation="MFVKKGDKVRVIAGKDKGTEAVVLTALPKVNKVIVEGVNIVKKH
                     QRPTNELPQGGIIEKEAAIHVSNVQVLDKNGVAGRVGYKFVDGKKVRYNKKSGEVLD"
     gene            complement(6472..6840)
                     /gene="rplN"
                     /locus_tag="VQ540_001113"
     CDS             complement(6472..6840)
                     /gene="rplN"
                     /locus_tag="VQ540_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HET2544927.1"
                     /translation="MIQTETRLKVADNSGAREILTIKVLGGSGRKFANIGDVIVASVK
                     QATPGGAVKKGDVVKAVIVRTKSGARRADGSYIKFDENAAVIIREDKTPRGTRIFGPV
                     ARELREGGFMKIVSLAPEVL"
     gene            complement(6866..7126)
                     /gene="rpsQ"
                     /locus_tag="VQ540_001114"
     CDS             complement(6866..7126)
                     /gene="rpsQ"
                     /locus_tag="VQ540_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HET2544928.1"
                     /translation="MERNNRKVLVGRVVSDKMDKTITVVVETKRNHPVYGKRINYSKK
                     YKAHDENNVAKEGDIVRIMETRPLSATKRFRLVEVVEEAVII"
     gene            complement(7151..7357)
                     /locus_tag="VQ540_001115"
     CDS             complement(7151..7357)
                     /locus_tag="VQ540_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HET2544929.1"
                     /translation="MKLNEVKEFVKELRGLSQEELAKRENELKKELFELRFQAATGQL
                     EQTARLKEVKKQIARIKTVQSEAK"
     gene            complement(7367..7780)
                     /gene="rplP"
                     /locus_tag="VQ540_001116"
     CDS             complement(7367..7780)
                     /gene="rplP"
                     /locus_tag="VQ540_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003029477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HET2544930.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQATTSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKV
                     MFEIAGVSEEIAREALRLASHKLPVKCKFVKREAE"
     gene            complement(7784..8437)
                     /gene="rpsC"
                     /locus_tag="VQ540_001117"
     CDS             complement(7784..8437)
                     /gene="rpsC"
                     /locus_tag="VQ540_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HET2544931.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYADYLHEDLAIRKFVQK
                     ELADAAVSTIEIERAVNKVNVSLHTAKPGMVIGKGGANVDALRAKLNKLTGKQVHINI
                     IEIKQPDLDAHLVGEGIARQLEQRVAFRRAQKQAIQRAMRAGAKGIKTQVSGRLNGAD
                     IARAEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEVLPARKNTKGGK"
     gene            complement(8450..8794)
                     /gene="rplV"
                     /locus_tag="VQ540_001118"
     CDS             complement(8450..8794)
                     /gene="rplV"
                     /locus_tag="VQ540_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HET2544932.1"
                     /translation="MAEITSAKAMARTVRVSPRKSRLVLDNIRGKSVADAIAILTFTP
                     NKAAEIILKVLNSAVANAENNFGLDKANLVVSEAFANEGPTMKRFRPRAKGSASPINK
                     RTAHITVAVAEK"
     gene            complement(8806..9087)
                     /gene="rpsS"
                     /locus_tag="VQ540_001119"
     CDS             complement(8806..9087)
                     /gene="rpsS"
                     /locus_tag="VQ540_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HET2544933.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQANDEKKKVIKTWSRRSTIFPSF
                     IGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYKGHAADDKKTRRK"
     gene            complement(9191..10024)
                     /gene="rplB"
                     /locus_tag="VQ540_001120"
     CDS             complement(9191..10024)
                     /gene="rplB"
                     /locus_tag="VQ540_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019790357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HET2544934.1"
                     /translation="MGIRVYKPTTNGRRNMTSLDFAEITTSTPEKSLLVALKSKAGRN
                     NNGRITVRHQGGGHKRFYRLVDFKRNKDNVEAVVKTIEYDPNRSANIALVHYTDGVKA
                     YIIAPKGLEVGQRIVSGPEADIKVGNALPLANIPVGTLIHNIELKPGRGGELVRAAGA
                     SAQVLGSEGKYVLVRLQSGEVRMILGTCRATVGVVGNEQHGLVNLGKAGRSRWKGIRP
                     TVRGSVMNPNDHPHGGGEGKAPVGRKAPSTPWGKPALGLKTRNKKAKSDKLIVRRRNE
                     K"
     gene            complement(10042..10338)
                     /locus_tag="VQ540_001121"
     CDS             complement(10042..10338)
                     /locus_tag="VQ540_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HET2544935.1"
                     /translation="MNLYDVIKKPVITESSMAQLEAGKYVFEVDTRAHKLLIKQAVEA
                     AFEGVKVANVNTINVKPKAKRVGRYTGFTNKTKKAIITLTADSKAIELFAAEAE"
     gene            complement(10338..10961)
                     /gene="rplD"
                     /locus_tag="VQ540_001122"
     CDS             complement(10338..10961)
                     /gene="rplD"
                     /locus_tag="VQ540_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HET2544936.1"
                     /translation="MANVTLFDQTGKEAGQVVLSDAVFGIEPNESVVFDVIISQRASL
                     RQGTHAVKNRSAVSGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYGYKLP
                     QKVRRLALKSVYSEKVAENKFVAVDALSFTAPKTAEFAKVLAALSIDSKVLVILEEGN
                     EFAALSARNLPNVKVATATTASVLDIANSDKLLVTQAAISKIEEVLA"
     gene            complement(10986..11612)
                     /gene="rplC"
                     /locus_tag="VQ540_001123"
     CDS             complement(10986..11612)
                     /gene="rplC"
                     /locus_tag="VQ540_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HET2544937.1"
                     /translation="MTKGILGKKVGMTQIFTEAGELIPVTVIEATPNVVLQVKTVETD
                     GYNAIQVGFDDKREVLSNKPAKGHVAKANTAPKRFIREFKNVEGLEVGAEITVETFAA
                     GDVVDVTGTSKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKGKNLAG
                     RMGGDRVTIQNLEVVQVVPEKNVILIKGNVPGAKKSLITIKSAVKAGK"
     gene            complement(11828..12136)
                     /gene="rpsJ"
                     /locus_tag="VQ540_001124"
     CDS             complement(11828..12136)
                     /gene="rpsJ"
                     /locus_tag="VQ540_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HET2544938.1"
                     /translation="MANKKIRIRLKAYEHRTLDTAAAKIVESATRTGAQVAGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTQKTVDALMKLDLPSGVNVEIKL
                     "
     gene            complement(12402..13019)
                     /locus_tag="VQ540_001125"
     CDS             complement(12402..13019)
                     /locus_tag="VQ540_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribulokinase"
                     /protein_id="HET2544939.1"
                     /translation="MKKKDLVDQLVSEIETGKVRTLGIYGHGASGKSTFAQELYQALD
                     STTVNLLETDPYITSGRYLVVPKDAPNQKVTASLPVAHELESLQRDILALQAGMDVLT
                     IEEPWKASEVLSGAKPILIVEGMSVGFLPKELFEKTICFYTDEETELKRRLARDTTVR
                     NRDASFILASHQMRREQYLRYYKETESKADILVDQSEDKFDVKRT"
     gene            complement(13016..13606)
                     /gene="nrdG"
                     /locus_tag="VQ540_001126"
     CDS             complement(13016..13606)
                     /gene="nrdG"
                     /locus_tag="VQ540_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001064213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HET2544940.1"
                     /translation="MNNPKPQEWKSEELSQGRIIDYKAFNFVDGEGVRNSLYVAGCMF
                     HCEGCYNVATWSFNAGIPYTAELEEQIMADLAQPYVQGLTLLGGEPFLNTGILLPLVK
                     RIRKELPDKDIWSWTGYTWEEMMLETPDKLELLSLIDILVDGRYDRTKRNLMLQFRGS
                     SNQRIIDVQKSLKSGQVVIWDKLNDGKEIYEQVKRE"
     gene            complement(13599..14105)
                     /locus_tag="VQ540_001127"
     CDS             complement(13599..14105)
                     /locus_tag="VQ540_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000423399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2544941.1"
                     /translation="MELRRPRLADKKAVLDMMTEFEKSQSAHDGGFWDVEDFSYEEWL
                     EGNRNKEMGIWLPENRVPSIQFVLFGESGCALGFLNLRLRLNEGLLNYAGHIGYSIRP
                     SERGKGYAKETLRQGLQVAKEKNIKKALVTCSVNNPASRAVILANGGIFEDARNGVER
                     YWIEVANE"
     gene            complement(14149..14289)
                     /locus_tag="VQ540_001128"
     CDS             complement(14149..14289)
                     /locus_tag="VQ540_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2544942.1"
                     /translation="MGKYQLDDKGRAQVTRYHEKHSKGGAGKKERLLSFREQFLNKNK
                     KK"
     gene            complement(14301..16508)
                     /gene="nrdD"
                     /locus_tag="VQ540_001129"
     CDS             complement(14301..16508)
                     /gene="nrdD"
                     /locus_tag="VQ540_001129"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004239081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HET2544943.1"
                     /translation="MIALEEKITILPTLFVEKRDGRRVVFDVDKIDKALHKAADKVMD
                     VTPLVEKRLNDLTERIITEIHSRFPQGIKIYEIQNIVEHELLEAKEYALAEEYITYRT
                     QRDFERSKATDINFSIHKLLNKDQTVVNENANKDSDVFNTQRDLTAGIVGKSIGLQML
                     PKHVANAHQKGDIHYHDLDYSPYTPMTNCCLIDFKGMLENGFKIGNAEVESPKSIQTA
                     TAQISQIIANVASSQYGGCSADRIDEILAPYAEKNYQKHLKDAEEWVLPEKREDYAWK
                     KTQKDIYDAMQSLEYEINTLFTSNGQTPFTSLGFGLGTSRFEREIQKAILNIRIKGLG
                     SEHRTAIFPKLIFTLKRGLNLEEGTPNYDIKQLALECATKRMYPDVLSYDKIVDLTGS
                     FKVPMGCRSFLQGWKDENGVEVNSGRMNLGVVTVNLPRIALESEGDMNKFWEIFNERM
                     NIAEDALVYRVERTKEATPANAPILYQYGAFGHRLGKEESVDQLFKNCRATVSLGYIG
                     LYEVATVFFGNSWESNPDAKEFTLDIIHDMKRRVEEWSDQYGYHFSIYSTPSESLTDR
                     FCRLDIDKFGSIPDITDKEYYTNSFHYDVRKNPTPFEKLDFEKVYPEAGASGGFIHYC
                     EYPVLQQNPKALEAVWDYAYDRVGYLGTNTPIDRCYKCDFEGDFEPTERGFACPNCGN
                     SDPKTVDVVKRTCGYLGNPQARPMVNGRHKEIAARVKHMNGSTIKIAGHQVTN"
     gene            complement(16628..18166)
                     /locus_tag="VQ540_001130"
     CDS             complement(16628..18166)
                     /locus_tag="VQ540_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
                     /protein_id="HET2544944.1"
                     /translation="MSVYGRVEEVHKENREPLEYQIEQESHHRESSRLPLVKILLWST
                     LVTGITLGVPLLLDLMSAQEVQDFYAGWALHQTGKIYSDYYGSQGLLYYLLTYVSQGG
                     FFFAIFEWLALVAGGFFLFRSADTLTEQGDQAGHLVTIFYMLVTGLAFGGGYATLLAL
                     PFLFAAFSLVAAYLSNPSHDKGFVRIGLALAGGFFFAPLSSLLFIAVVSLGLLVFNLG
                     HRRFAHGFYQFLAVALGFSLVFYPTAYYSAATGSFGDAISGIRYPIDSIRFDFTSKIL
                     ENMFFYGLLSLGLGFVVCIFLGLFQSKPFKLYVISVPASLVVILGLILLFFSQEPLHA
                     SYLMVVFPVFLLLLVTNIKSQQRGRSARRSRRETPVSLWSRFFKGNLYLLVFGFVYLL
                     SVPFLMKFVLYPVPYQERNRLADLVKEETNTEDAIYAWDDTATLYRKSERLSPSAILS
                     PLHYTATEENRNKLLNDLKEKQPKVIVVNDKVVVWSEVETLLKENYQQVKTDYSEFKV
                     YKIK"
     gene            complement(18203..18346)
                     /locus_tag="VQ540_001131"
     CDS             complement(18203..18346)
                     /locus_tag="VQ540_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000956126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2544945.1"
                     /translation="MLTKEEVNDMIEFKQTHLHRFREIETFVKLCKKSLKQPSQADNP
                     RTF"
     gene            complement(18424..19956)
                     /gene="cls"
                     /locus_tag="VQ540_001132"
     CDS             complement(18424..19956)
                     /gene="cls"
                     /locus_tag="VQ540_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000877342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HET2544946.1"
                     /translation="MKYRKFQLLMSKYGFSLSIMLLELCLVFGLFLYLGRMAPILWIT
                     VLILLSIITIISIVNRNTTPENKVTWLLVAFVPVFGPLLYLMFGERRLSKKEIKQLKK
                     LGSMHFQEANSQLLKEKLKESDKAAYGVIKSLLSMDTNADIYDQTASTFFPNGEAMWK
                     KMVEDLKKAEKFIFLEYYIIEEGLMWNRILDILEQKVAQGVEVKMLYDDIGCMATLTG
                     DYAHRLRQLGIEAHKFNKVIPRLTVAYNNRDHRKILIVDGQIAYTGGVNLADEYINHV
                     ERFGYWKDSGIRLDGLAVKALTRLFLTTWYINRGEISDFDQYHLENHSIPSDGLTIPY
                     GSGPKPIFRAQVGKKVYQSLINQATESVYITTPYLIIDYDLTETIKNAAMRGVDVRII
                     TPYIPDKKFIQLVTRGAYPDLLSAGVRIYEYSPGFIHSKQMLVDEDFAVVGTINLDYR
                     SLVHHYENAVLLYKTPSIREIARDFRNIFADSQEVYPHSIKTSWYQKLVKEIAQLFAP
                     IL"
     gene            complement(20102..20659)
                     /locus_tag="VQ540_001133"
     CDS             complement(20102..20659)
                     /locus_tag="VQ540_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipocalin/fatty acid-binding family protein"
                     /protein_id="HET2544947.1"
                     /translation="MTPLFELVILGELLVRENFSKLVAERKFIMKLKRFTLSLASLAS
                     FSLLVACSQRAQQVQQPVAQQQVQQPAQQPAQQNTNTANAGGNQNQAAPVQNQPVAQP
                     TDIDGTYTGQDDGDRITLVVTGTTGTWTELESDGDQKVKQVTFDSANQRMIIGDDVKI
                     YTVNGNQIVVDDMDRDPSDQIVLTK"
     gene            complement(20656..21906)
                     /locus_tag="VQ540_001134"
     CDS             complement(20656..21906)
                     /locus_tag="VQ540_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000464354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HET2544948.1"
                     /translation="MFEVEEWLHSRIGLNFRSGLGRIQQAVDLLGNPEQSYPIIHVTG
                     TNGKGSTIAFMRELFMGHGKKVATFTSPHIVSINDRICINGQPIADADFIRLADQVKE
                     MEKTLLQTPDQLSFFEMLTLVAFLYFREQEVDLVLLEVGIGGLLDTTNVVTGELAVIT
                     SIGLDHQETLGDSLEAIAEQKAGIFKAGKKAVIAKLPPEARLVCQKKAESLAVNLYQA
                     GQDFLMLNGDFSSSLLNFSQLNIGLEGVYQQENAALALQTFLLFMGEGKEAVDEQAVR
                     KALEQTHWAGRLERIRPQIYLDGAHNLPALTRLVEFIKEKEQEGYRPQILFGALKRKD
                     YQGMLGYLTEKLPQVELKVTGFDYQGALDERDVTGYDIVSSCREFISSFEERADAQDL
                     LFVTGSLYFISEVRGYLLDREQIN"
     gene            complement(22114..22419)
                     /locus_tag="VQ540_001135"
     CDS             complement(22114..22419)
                     /locus_tag="VQ540_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HET2544949.1"
                     /translation="MSHDHNHDHEERELITLVDEQGNETLFEILLTIDGKEEFGKNYV
                     LLVPVNAEEDEDGQVEIQAYSFIENEDGTEGELQPIPEDSEDEWNMIEEVFNSFMEE"
     gene            complement(22435..22854)
                     /gene="ruvX"
                     /locus_tag="VQ540_001136"
     CDS             complement(22435..22854)
                     /gene="ruvX"
                     /locus_tag="VQ540_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HET2544950.1"
                     /translation="MRIMGLDVGSKTVGVAISDPLGFTAQGLEIIQINEEQGQFGFDR
                     VKELVDTYKVERFVVGLPKNMNNTSGPRVEASQAYGAKLEEFFGLPLDYQDERLTTVA
                     AERMLIEQADISRNKRKKVIDKLAAQLILQNYLDRKF"
     gene            complement(22858..23124)
                     /locus_tag="VQ540_001137"
     CDS             complement(22858..23124)
                     /locus_tag="VQ540_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HET2544951.1"
                     /translation="MGFTEETVRFKLDDSNKKEISETLTDVYASLNDKGYNPINQIVG
                     YVLSGDPAYVPRYNNARNQIRKYERDEIVEELVRYYLKGQGVDL"
     gene            complement(23211..23780)
                     /locus_tag="VQ540_001138"
     CDS             complement(23211..23780)
                     /locus_tag="VQ540_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HET2544952.1"
                     /translation="MKKIVLVSLAFLFVLVGCGQKKETGPATKTEKDTLQSALPVIEN
                     AEKNTVVTKTLVLPKSDDGSQQTQTITYKDKTFLSLTIQQKRPVSDELKTYIDQHGVE
                     ETQKALLEAEEKDKSIIEARKLAGFKLETKLLSATELQTTTSFDFQVLDVKKASQLEH
                     LKNIGLENLLKNEPSKYISDRLANGATEQ"
     gene            complement(23846..24244)
                     /gene="spx"
                     /locus_tag="VQ540_001139"
     CDS             complement(23846..24244)
                     /gene="spx"
                     /locus_tag="VQ540_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HET2544953.1"
                     /translation="MIKIYTVSSCTSCKKAKTWLNAHQLSYKEQNLGKEGITREELLD
                     ILTKTDNGIASIVSSKNRYAKALGVDIEDLSVNEVLNLIMETPRILKSPILVDEKRLQ
                     VGYKEDDIRAFLPRSVRNVENAEARLRAAL"
BASE COUNT         6740 a         5398 c         4560 g         7629 t
ORIGIN      
        1 tttttcaata tctgagaaga catcattgat atcttgatta ccttcgatgt catgaaccaa
       61 acctttggca cggtagtgag caatgattgg ttctccttga gcaatattaa catccaaacg
      121 acgttttact gtctcaggct tatcatcttc acgttggtag taatcttctt ctttatagtc
      181 aactggtggg ttaaagacct tgtggaaagt ttctccagtt acgcggtgga tgatacggcc
      241 actcaaacgt tccaagaggc tgtcagggtt cacttcaata ttgataatac cttctagttc
      301 aatgccaagt tcagccaatg ttttgtccaa ggcatgagct tgttcaattg tacgtgggta
      361 accatccaat aagaatcctg tttctttaat atcatcttgt gaaaggcgtt cttttacgat
      421 tccatttgta acttcgtcag gaaccaattc acccttgtca atatatgact tagcaagaac
      481 acccatttca gtttgatttg ccattgcagc gcggaacata tcacctgttg agatatgtgc
      541 aacatggaat tgttctacga tttttgctgc ttgagttccc ttacctgcac caggtaagcc
      601 cataatcaaa agattcatga tttgatctcc ttattttatt tttaaataga agcaaaaagt
      661 cttttcaccc ctatttaaaa acaaaataga agaggggaga tccaactctt acaaatgtca
      721 gagtttaaac ctccactccc tcagtattta ctgattcagt aaatactttt attctgttct
      781 gtccatgaaa ccaacatact tacgtttcaa taggtaacct tccaattgct tgattccttc
      841 gatacctgta gagataatga tcaagagact tgttccacca aaggcaacaa catcagaaag
      901 accaaataca tctttagctg caatcggtaa aatggaaatc acaccaagga agagggaacc
      961 aacagttgca agacgacgaa gaagtttaga catatattct tctgtacctt taccaggacg
     1021 aactccatgg atataggcac cactcttttg taggctctct gctgcttttt caggattaat
     1081 ctgtacaaac gtatagaaga atgtaaagag aataatcaac aaagcataca tggcaatacc
     1141 agttggagaa gtagttgcca acatctcttg tgctaccctt acccaagccc aatcatgacc
     1201 tgtggcactc aaaaactgaa gaatagccgc aggcgctgca gtaatcgaac tggcaaagat
     1261 aacagggata actccagcag ggtttacctt taacggaagg taagagctag atggagcacc
     1321 ttgtgcaacc ttagtatatt ggattggaat tttgtattct gcttgttgaa cataagttgt
     1381 aaagtaaata atcaacaata cagtaataat caaaatgatt acgaaaatga tagatgaagt
     1441 gatacggcta cttgggacgt tcacaaagta gtccacatag atgccctgaa tcatctctgg
     1501 aattgaggaa acaatcccgg caaagataat catggaaaca ccgtttccgt atcccttatc
     1561 tgtaatttgc tcacccaacc aagtgacaat catactacca gctgttaaga tgataccaat
     1621 cgtcagaaaa acttgtggag ttaaagcagt tttaatcaat tgagctccag ccaaggtatt
     1681 aaaaccagct gtaatcccga tagattgcac aaaagcgaga actagagcaa tataacgagt
     1741 agcttgattc aattttcttc gacctacttc cccttgttta ccccactcta caaacttggg
     1801 taaaatatcc atttgcaaga gttggacaac aatagaagcg gtgatatagg gactaactcc
     1861 tagggcaaaa atcgaaaagt tttttagggc attccccgac accaagctca acatgtttaa
     1921 gaaggataat ccacttaaag cattcaagct attggcattc acaccaggaa ctgtaatgct
     1981 agttccgata cgaaagacca aaacgataaa aattgtaaat aaaatttttg atcgaacctg
     2041 cttgacttta agagcttctc ttaataattt aaaaaacata ggtcacctct cttagatgac
     2101 ttctactgaa ccacctttag cagtgatagc ttcttcagct gatttagaga atttagctgc
     2161 tttcacagtc aatttcttag tcaactcacc gttaccaaga attttaatac ctgacttttc
     2221 agctttaaca attcctgctt cgataagaac aactggagtt acttcagcac catcttcaaa
     2281 gacgttcaat tggtcaaggt tcacaattgc gtattcttta gcgttgatgt tagtgaatcc
     2341 acgttttgga agacgacgga acaatggagt ttgtccacct tcaaaaccaa ggcgaactcc
     2401 gccaccgcta cgagcttttt gacctttttg accacgacca gatgttttac cgttacctga
     2461 tgaagtacca cgaccaacgc ggttacgtac tttacgagaa ccttctgcag gtttcaattc
     2521 atgaagtttc atttttattt tctcctcttt tgtaaaatgc tagcgccgat aagggagaaa
     2581 aggttgtctc ccccatcaac tcgcctatac gatgtcatca tagatgacta tatctagttt
     2641 taggggatgg tacagtgcac atcccctaaa acttcattag tttacttctt caactgttac
     2701 taagtgagat actgctgtaa tcataccacg gatagcagcg ttatcttctt taataacaga
     2761 gctgttcaat ttgccaagtc caagtgctac aacagtttta cgttgtgatg gaatgcgtcc
     2821 gattggagac ttagtcaaag taattttaat ttgagccatt ttatcccctt tcttatgcca
     2881 aatcagaaac tgaaatacca cgaagggcag caatttcttc agcgcgtttc aattgtttca
     2941 aaccttcaac agttgcacga acaatgttga ttggagtgtt agaaccaagt gatttagatg
     3001 taatatctgc cacacctgcc aattccacaa cggcacgaac tgcaccacca gcggcaactc
     3061 cagaaccttc tacagcaggt ttcaacaata ctttagctcc accgaattct gaaagaactt
     3121 cgtgtgggat tgttgttcca accataggaa cttcgatcaa gtttttctta gcatcatcta
     3181 ctgctttacg gattgcttct ggaacttctt gagctttacc agtaccaaat cctacgcgac
     3241 cattgtggtc accaacaaca acaagagctg cgaaacgaag acgacgtcca cctttaacaa
     3301 cttttgtaac acggttgaca gcaactacgc gttcttctaa ttcaactgca ttgtctttaa
     3361 atgccatttt ctagtgtcct cctattagaa tttcaatccg ttttcacgag ctgcatcagc
     3421 caaagctttc acacgtccgt gatatagata tccaccgcgg tcgaacacca cttctgaaat
     3481 acctttagcg tttgcacgtt ctgcaacgag tttaccgaca gcaacggctt gttcagtttt
     3541 agttcctttt gaaacttctt tatcaagagt tgaagcactt gcgagcgtta cacccgctac
     3601 gtcatcaatc acttgagcgt agatgcctgt attagaacgg aatacgttca aacgtgggcg
     3661 atcagcagtt ccagagagtt ttccgcgaac gcgacggtgg cgtttttggc ggagtttgtt
     3721 tttatctggt tttgaaatca cagttttcac ctctttagtt ttaaatcgtg tgctatgcac
     3781 aaagttggaa aataggttgg tggttgatga tcaaccactc aacattattt acctgtttta
     3841 ccttctttac ggcgaacgaa ttcaccaacg taacggatac ctttaccttt atatggttct
     3901 ggtgaacgaa ggctacgtac gtaagcagct gtttgaccaa ctacttcttt tgaaattccg
     3961 ctaacaacga ttgttgttgg gtttggaagt tcaaaagtaa ttccttctgg agcttcaact
     4021 tcgtctggat gagatttacc aacagccaaa acaagtttag atccttgaag ctgtgcacgg
     4081 taaccaaccc cacgcatttc aagttctttc ttgaatcctt ctgatacacc aacaaccatg
     4141 ttgttcaaaa gggcacgagt agttccgtgg atagttttca tttcttttga atcgtttgga
     4201 cggtgaagag ttatttcagt accttccaca cggatttcaa tatcttttga gaactcacga
     4261 gtaagttctc ctttaggtcc ttttacagtt acaacgttgt cattgttagc gagttcaaca
     4321 ccagcaggca acacgataac tttattacca atacgtgaca tgtttatttt ctcctgttaa
     4381 attgtcaggc cagaacggcc agttttcacg gggttcagat acttatttag ttcaagagct
     4441 gaactgaaca cgctctaaga actgtgcaaa atagataagt tggcttgttt gtaaacaaac
     4501 ttctccaact tcctaatttt gctttgttct ttacgagctt tgtatcttga ttttaccaaa
     4561 cgtaagcgat aacctcacca ccaacattct tttggcgtgc ttctttatca gtaagcaaac
     4621 cttcagaagt tgaaaggatg gcaattccaa gtccgttaag aacttttgga aggtcttcac
     4681 gttttttgta gacacgaagt cctggtttag aaacacgttt caagttagtg ataactttct
     4741 caccatttgg tccgtattta agaaatacac ggatgacgcc ttgtttgtca tcttcaatga
     4801 tttcaacgtt ttttacaaaa ccttcgcgtt taaggatttc agcaatccct tttttgatgt
     4861 ttgatgcagg tacttcaagt acttcgtgtt tagcttggtt agcattacga atacgagtta
     4921 ggaagtctgc gattgggtca gtcataacca ttttgttttt ctcctcttac tagtagtttg
     4981 caagttgcac ttgctagtta atacatgata caaagagcgt aacagcacga gcaaaaatag
     5041 acaatttaat gcagaagcaa tgctccaaag caaattggtc ttttttgcca aagctgtagc
     5101 tcgtgttcaa attggcaagc ccaattgaac ccgggctaaa ctctgtgtga aaaagataaa
     5161 ctttcctaga aactttagtt tcttcgtcaa gtttcctatt tttacttgga gttttgacgc
     5221 tcttgatatc ttaaattacc aagatgcttt tgttacacca ggaatttgac ctttatgcgc
     5281 aagttcgcga aaagcgatac gactcagacc aaatttgcgg taaactgaat gtgggcgccc
     5341 cgtaactcta caacgattat gtaaacgagt cggtgaggcg ttgcgaggta atttagataa
     5401 accttcgtag tcccctgccg cctttaatgc agcacgtttt tcagcataac ggtcaacaat
     5461 tttttggcgt ttagcctctc tagctaccat tgatttttta gccattagat ttacctccta
     5521 tattattttg caaaaggcat tccaaggcct gtaagcaatg cacgtgactc ttcgtcagtg
     5581 ttagcagttg ttacgataac gatgtcaaga ccacgagttt tgtcaacgtc atcgaagttg
     5641 atttctggga agattaattg ttctttcaca ccaagtgtgt agttcccgcg tccatcaaat
     5701 gattttgttg gaacaccgtg gaagtcacgt acacgtggaa gtgaaactga taccaattta
     5761 tccaagaatt cgtacatacg ttcaccacga agggtaactt ttgcaccgat cgcaacacct
     5821 tcacgaagac ggaagccggc gattgatttt ttagctttag tgataagtgg tttttgacct
     5881 gagataagtg ccaattcttc agcagctttt tcaaggcttt tagcgtttga tacagcttca
     5941 ccaacaccca tgttcaaaac aatcttatct actttaggca cagccatcac tgatgagtag
     6001 ttgaattgtt ctgtcaaagc aggaactact tcattaagat atttttcttt taaacgattt
     6061 gccattatac ttctcctttc cttcgtgatt aatcaagcac ttcgcctgat tttttgttgt
     6121 agcgaacttt tttaccgtct acaaatttgt aaccaacacg accagctaca ccatttttgt
     6181 ccaaaacttg aacgtttgat acgtggatag ctgcttcttt ctcgatgata ccaccttgag
     6241 gaagctcgtt agttggacgt tggtgtttct taacaatgtt aacaccttca acgataactt
     6301 tgtttacttt tggaagggca gtaaggacaa cagcttctgt tcccttatct ttaccagcga
     6361 ttacgcgaac tttgtcgcct ttttttacaa acattaggtt tctccttgat ttttcttacg
     6421 cccataaggg caccctagct tgaagctagg ggactagttt gttcctaaaa attaaagtac
     6481 ttctggagca agtgacacga tcttcatgaa gccaccttca cgcaattcac gtgcaactgg
     6541 gccaaagata cgtgttccgc gaggagtttt gtcttcacgg atgataactg ctgcgttttc
     6601 gtcaaatttg atgtatgaac catcagcacg acgagcacct gatttagtac gaacgataac
     6661 tgctttaaca acgtcacctt ttttaaccgc accaccagga gtagcttgtt ttacagatgc
     6721 cacgataaca tcaccgatgt ttgcaaattt acgtcctgaa ccaccaagaa ctttgatagt
     6781 caagatttcg cgagcaccgc tgttgtctgc gactttcaaa cgagtttctg tttgaatcat
     6841 ttcagttttc tcctttcagg tttgattaga tgatgaccgc ttcttcaaca acttctacaa
     6901 gacggaaacg ttttgtagct gaaagcgggc gagtttccat gatacgtacg atatcgcctt
     6961 ctttggcaac attgttttca tcatgagctt tgtatttttt agagtagtta atacgtttac
     7021 catagactgg gtggttacgt tttgtttcaa ctacaactgt gattgtcttg tccattttgt
     7081 cagatacaac acgtccaaca agaactttac gattattgcg ttccattgaa atttctcctt
     7141 ccctagtcta ttatttcgct tcagattgaa ctgttttgat acgagcgatt tgttttttaa
     7201 cttctttcaa gcgagctgtt tgttccaatt gaccagtagc agcttggaaa cgaagttcaa
     7261 acaattcttt tttcaattcg ttttcgcgct tcgcgagttc ttcttgagaa agaccacgaa
     7321 gttctttaac aaattctttt acttcattaa gtttcatgcc ttctccttat tctgcttcac
     7381 gttttacgaa tttacattta actggcaatt tgtggctagc aagtcgaagc gcttcacgtg
     7441 caatctcttc agatacacca gcgatttcga acatcacttt accacgttta actggtgcta
     7501 cccaaccttc aggtgcccct ttaccagatc ccatacgcac accgatagct ttagcagtgt
     7561 atgatttgtg tgggaagatt ttaatccaaa ctttaccacc acgtttcatg taacgagtca
     7621 tggcgatacg agcagcttcg atttggcggt tagtgatcca gtggctagtt gtagcttgaa
     7681 gaccgtattc accgaatgct acttcttttc caccttttgc ttcaccgcgc atttttccac
     7741 ggaactcacg acggtgttta acacgtttag gtactaacat tggttattta cctcctttag
     7801 tgtttttacg agctggaaga acttcaccac ggtagatcca tactttaaca ccaagtttac
     7861 cgtatgtagt atctgcttct tcccaagcgt aatcgatatc tgcacgaagt gtgtgaagcg
     7921 gaacagttcc ttcagagtat ccttcagcac gggcgatatc tgcaccgttc aaacgacctg
     7981 atacttgagt tttgattcct ttagctccag cacgcattgc acgttggatt gcttgttttt
     8041 gtgcacgacg gaaagcaaca cgttgctcca attgacgagc aattccttca cctacaaggt
     8101 gagcatccaa atcaggttgt ttgatttcga tgatgttgat gtgtacttgt tttccagtca
     8161 atttgttaag ttttgcacgg agtgcatcaa cgttagcacc acctttaccg ataaccatac
     8221 ctggtttagc agtgtgaagt gaaacgttaa ctttgtttac tgcgcgttcg atttcaatag
     8281 ttgaaactgc tgcgtcagca agttcttttt gaacgaattt acggattgca agatcttcat
     8341 gaaggtaatc cgcgtattct ttttcagcat accatttggc atcccaatca cggatgatgc
     8401 cgacacgcat accaattgga tgtacttttt gacccacgat tttacctcct tatttttctg
     8461 caacagctac agtgatgtga gctgtacgtt tgttgattgg tgaagctgaa cctttcgcac
     8521 gtggacggaa acgtttcata gttggtcctt cgtttgcgaa tgcttcagat actaccaaat
     8581 tagctttatc caaaccaaag ttgttttcag cgttagctac agctgagttc aaaactttca
     8641 agatgatttc agcagctttg tttggagtga atgtcaagat tgcgattgca tcggctacgc
     8701 ttttaccacg gatgttatca agaacaagac gtgatttacg aggtgaaaca cgtactgtac
     8761 gagccattgc tttagctgaa gtaatttctg ccatttatgt tctccttatt ttctacgtgt
     8821 tttcttgtcg tctgcagcgt gacctttgta agtacgagtt ggtgcaaatt caccaagttt
     8881 gtggcctacc atgtcttctt ggatgtaaac aggtacgtgt ttacgtccgt cataaactgc
     8941 aatagtgtaa ccaatgaaac ttgggaagat cgttgaacga cgtgaccaag ttttaataac
     9001 ttttttcttt tcgtcgttag cttgagcttc aacttttttc atcaaatgct catcgacgaa
     9061 aggtcctttt ttaagactgc gtcccatttt tatattttct cctttaaatg ttgtaccaca
     9121 gcggcttgca ctcctatgga gcgctaccga gctggcggat ttactagttg cttaagcgac
     9181 tagtttaata ttatttctcg ttgcgacgac gaacgataag tttgtcagat ttcgctttct
     9241 tgttacgagt tttaagacca agagcaggtt tgccccatgg agtagatggt gctttacgac
     9301 caactggtgc tttaccttca ccaccaccgt gtgggtgatc gttagggttc attacagaac
     9361 cacgaactgt tgggcggata cctttccaac ggctacgtcc tgctttacca aggtttacaa
     9421 gtccatgttg ttcgtttccg acaacaccaa ctgtagcacg gcaagttcca agaatcatac
     9481 gaacttcacc tgattgaaga cgaacaagaa catatttacc ttcagaaccc aatacttgag
     9541 cagatgcacc agcagcacgt accaattcac caccacgacc tggtttcaac tcgatgttgt
     9601 gaatcaaagt accaactggg atgttagcaa gtggaagagc gtttccgact ttgatatctg
     9661 cttctggacc tgaaacgata cgttgaccta cttcaagacc ttttggagcg atgatgtatg
     9721 ctttcacacc gtcagtgtag tgtacaagag cgatgtttgc agaacggttt ggatcgtact
     9781 cgattgtttt aacaactgct tcaacgttgt ctttattacg tttgaagtca accaaacggt
     9841 aaaaacgttt gtgtccacca ccttggtgac gaactgtgat acgaccgttg ttgttacgac
     9901 cagccttgct cttcaatgca acaagcaatg atttttcagg agtgcttgtt gtgatttcag
     9961 cgaaatccaa agaagtcata ttacggcgac cgtttgttgt tggtttataa acacgaattc
    10021 ccacgatatt tcctccttag attattcagc ttcagcagca aacaactcga ttgctttaga
    10081 atcagctgta agtgtgatga tagctttttt agttttgtta gtaaaaccag tgtaacgtcc
    10141 aacacgttta gcttttggtt ttacgttgat tgtgttaaca ttggcaactt taacaccttc
    10201 gaaagcagct tcaacagctt gcttgatcaa aagtttgtgt gcacgagtgt caacttcaaa
    10261 tacatatttt cctgcttcaa gttgagccat tgagctttca gtgatgacag gttttttgat
    10321 aacatcatac aaattcatta tgcaagaacc tcctcgattt tagagatagc tgcttgtgtg
    10381 acaagaagtt tgtcgctatt tgcgatgtca agaacacttg cagttgtagc agttgcaact
    10441 ttcacgtttg gaaggttacg agctgaaaga gctgcgaatt catttccttc ttcaaggata
    10501 acaagaactt tagaatcgat gctcaatgct gcaagaactt ttgcaaattc agcagttttt
    10561 ggagctgtaa atgaaagagc gtctacagct acgaatttgt tttcagcaac tttttcagag
    10621 taaactgatt taagagctag gcgacgaact ttttgtggaa gtttgtagcc gtatgaacgt
    10681 ggagttggtc cgaagacaac accaccacca cgccattgtg gtgagcggat agaaccttga
    10741 cgagcacgtc cagttccttt ttgacgccat ggtttgcgtc caccacctga tactgcagag
    10801 cggtttttaa cagcgtgtgt tccttgacga aggcttgcgc gttggctgat gattacatca
    10861 aacacaactg attcatttgg ttcgatacca aatactgcat cgctaagaac aacttggcca
    10921 gcttctttac cagtttggtc aaataatgtt acgtttgcca ttgtgactga tttccccttt
    10981 ctttattatt taccagcttt aactgctgat ttgatagtga taagagattt cttagcacct
    11041 ggtacgttac ctttgataag gataacgttc ttttctggaa caacttgtac aacttcaagg
    11101 ttttgaattg ttacgcggtc gccacccata cgccctgcaa ggtttttacc tttgaatacg
    11161 cggttaggtg caacaggtcc catagaacct ggacgacggt ggtaacgaga accgtgagcc
    11221 attggtccac gtgattgtcc gtggcgtttg ataacacctt ggaaaccttt acctttagaa
    11281 gtaccagtta cgtcaacaac gtctccagct gcgaatgttt caactgtaat ttcagcacca
    11341 acttccaagc cttcaacgtt tttgaattca cgaatgaagc gcttaggagc cgtgttagct
    11401 ttcgctacat gtcctttagc aggtttgttg ctcaatactt cgcgtttgtc atcgaaacca
    11461 acttggatag cgttgtatcc gtctgtttca acagttttaa cttgaagaac aacgtttgga
    11521 gttgcttcaa taactgttac agggatcaat tcgccagctt cagtgaagat ttgagtcatt
    11581 cccacttttt tccctaagat tccttttgtc atgagaaaat agttcctttt ctatattttt
    11641 attcaaaaag tttttaacga gcgtttttta tgctcaagtc taagatacaa agggcgtcaa
    11701 actcaacgtg aaaataggaa actgacacag tgtctagcag acgcgaggaa gtttatcttt
    11761 ttcacaccga gtttagcccg tgttcaatta gattgaaaca ccagcctctg ctcttttata
    11821 ttttagatta aagtttgatt tctacgttta caccacttgg aagatccaat ttcatcaagg
    11881 catcaactgt tttttgagtt gggttaacga tatcgatcaa acgtttgtgt gtacgcattt
    11941 caaattgttc gcgagagtct ttgtatttgt gagtcgcacg aatgattgtg tagaggctac
    12001 gttcagttgg aagtgggatt ggacccgcaa cttgtgcacc tgtacgagta gctgattcta
    12061 cgatttttgc agccgctgtg tcaagcgtac ggtgttcgta agctttcaaa cggatacgga
    12121 tttttttgtt tgccatcttt ttctcctttt cgtctattta agataatagg ctagctccac
    12181 aagaaaaccg acgcggtgtt gcgtggcaat gcaaccgagc gtgtcgcaac ctcttgcatc
    12241 aaaactaagg ctgtaattta cagcaccata atagaataac acaaatcccc tgcgattgca
    12301 agggatttgt taggtttttt cgttttttgg ggatgaaact gttttcctac tttttctttc
    12361 taaaattagg gattttcttc tatatttctt ctatacataa gttaagtcct cttgacatca
    12421 aatttatctt ctgattggtc cactaagata tccgccttag actcagtttc tttatagtat
    12481 cgcagatact gctcccgtct catctgatgg ctagccaata taaaggatgc atcgcgattt
    12541 ctcacagtcg tatctctagc aaggcgtcgc tttaattcgg tctcctcatc cgtgtagaaa
    12601 cagatggttt tttcaaagag ttccttgggt agaaagccaa cagacatccc ttcgacaatc
    12661 aaaattggtt tggctccaga caagacctca ctagccttcc aaggttcttc aattgtcaag
    12721 acatccatac ccgcctgcaa ggcaaggata tctctctgca aactctccag ttcatgcgcc
    12781 actggcagac tggctgtcac cttttgattc ggcgcgtcct tgggtactac caaatagcgt
    12841 ccggaggtga tatagggatc tgtttctagc aaatttactg tagtagaatc taaagcttgg
    12901 tacaattcct gtgcaaaggt tgatttacct gaagctccat gaccgtatat tcccagtgtc
    12961 ctgactttcc ccgtctcgat ctctgagact agttggtcta ctaagtcttt tttcttcatt
    13021 ctctcttcac ctgttcatag atttcttttc cgtcattgag cttgtcccaa atcactactt
    13081 gcccactttt gagcgatttt tgcacatcga taattcgttg gttagacgaa cctcgaaact
    13141 ggagcataag atttctctta gttcgatcat atcttccatc gacaagaatg tcaatcagtg
    13201 acaagagttc cagtttatct ggagtttcca acatcatttc ttcccaagtg tagcccgtcc
    13261 aggaccagat gtccttgtct ggcaattcct tccgaatccg cttaacaagt ggcaagagaa
    13321 tcccagtatt aagaaaaggc tcccctccta gtaaggttaa cccctgaaca taaggctggg
    13381 caagatctgc cataatctgt tcttccaact cagctgtata gggaatgcct gcattgaagg
    13441 accaggtcgc tacattataa cacccctcgc agtgaaacat acagcctgct acatagagag
    13501 agttacgcac gccttcgcca tcaacaaagt taaaggcctt gtagtcaatg atacgacctt
    13561 gactaagttc ctcgcttttc cattcttgtg gttttggatt attcattcgc tacctctatc
    13621 caataacgct cgactccatt gcgagcatcc tcaaatattc caccatttgc tagaatgact
    13681 gctctgctag caggattatt cacgctacag gtcaccagag ctttcttgat gttcttttcc
    13741 ttagcaactt gcaagccctg acggagagtc tcttttgcat aacccttgcc tctttcagat
    13801 ggacggatgg agtagccaat gtggccagca taattcagta acccctcatt cagtctcaat
    13861 cgcagattca aaaatcctag agcacaacct gattcaccaa acaatacgaa ctgtatcgat
    13921 ggaacgcgat tttcaggtag ccatattccc atttctttat tacggttacc ttctagccac
    13981 tcctcgtaag aaaaatcctc aacatcccaa aatcctccat catgggctga ttggctcttt
    14041 tcaaactctg tcatcatatc taaaacagct ttcttatccg ctaatcttgg tctgcgtaat
    14101 tccatcctta cctcccacta tgagaaaagc gagagctggc tctcactttt attttttctt
    14161 gttcttgttt aaaaattgtt ctctgaagct aagcaagcgt tctttcttac cagctccacc
    14221 tttagagtgt ttctcgtgat aacgggtcac ttgtgcgcgc cccttatcgt ctagttgata
    14281 ttttcccatt tcatttcttt ctaatttgtt acttgatgcc cagctatttt aatcgttgaa
    14341 ccattcatat gtttgacacg cgcagcgatt tccttgtgac gcccgttgac catcggtctt
    14401 gcttgaggat tacctaggta gccacaagtt cgcttcacca catctactgt tttagggtcg
    14461 ctattgccac agtttggaca agcaaaccct ctctcagttg gttcaaaatc cccttcaaag
    14521 tcacacttgt agcaacggtc aatcggagta ttggtgccta gatagcctac acggtcataa
    14581 gcataatccc agacagcttc caaggccttt ggattttgct gaaggactgg atactcacaa
    14641 taatggatga aaccacctga cgcacctgct tctggataga ctttctcaaa gtccaatttt
    14701 tcaaacggtg ttggattttt acgaacatcg tagtggaaag agttggtgta gtattccttg
    14761 tctgtgatat caggaataga gccaaacttg tctatatcta gtcggcagaa acggtctgtc
    14821 agactttcgg atggtgttga gtagatagag aaatggtagc catattggtc tgaccactct
    14881 tctacacggc gtttcatatc gtgaatgatg tctagcgtga attccttagc atctggatta
    14941 ctttcccagc tgttaccaaa gaaaactgtc gctacttcat acaagccgat atagcccagc
    15001 gaaacggtcg cacgacaatt cttaaagagc tggtcaacac tttcttcttt acctagacga
    15061 tggccaaaag caccgtactg ataaaggata ggagcattcg ctggtgtcgc ctctttagtg
    15121 cgttcgacac ggtaaacaag agcatcttct gcgatattca ttcgctcgtt gaagatttcc
    15181 cagaacttat tcatatcacc ttcagactca agagcaatac gaggcagatt aaccgtcaca
    15241 acacccagat tcatgcgacc tgaattgact tctacaccat tttcatcctt ccatccttgg
    15301 aggaaagaac ggcaacccat aggcaccttg aaggatcctg tcaagtcaac aatcttatcg
    15361 taagataaaa catctggata catccgtttg gttgcacact caagagccaa ctgcttgatg
    15421 tcgtagttgg gagttccttc ctctaaatta aggcctcttt tcagagtgaa aataagttta
    15481 ggaaagatag ccgtacggtg ttctgaacca agacccttga tgcgaatgtt taaaatagct
    15541 ttttgaattt ctcgttcaaa acgactggtt cccagaccaa aacctagcga agtaaaaggt
    15601 gtttgtccat ttgaagtgaa gagagtattg atttcatact caagagattg catggcatcg
    15661 tagatgtcct tttgcgtttt cttccaagcg taatcttccc gtttttcagg caatacccac
    15721 tcttctgcat ctttgagatg tttttgatag ttcttctctg cataaggcgc caaaatttca
    15781 tcgatacggt cagctgaaca gccaccgtac tggctagaag caacgttggc aatgatttga
    15841 gaaatctgtg ctgtcgcagt ctggatagac ttgggactct ctacctctgc atttccaatc
    15901 ttaaaaccat tttccaacat acccttaaaa tcaatcaaac agcagttggt cataggggta
    15961 tagggactgt agtccaaatc gtgatagtgg atatccccct tttggtgggc attggctacg
    16021 tgcttaggaa gcatttgcag tccgattgat ttcccaacaa tccctgctgt caaatcacgc
    16081 tgagtgttaa agacatcact gtctttatta gcattttcat tgacaactgt ctggtctttg
    16141 ttgagaagtt tatgaatact aaagttgata tccgtcgctt ttgagcgctc aaaatccctc
    16201 tgtgtccgat aagtaatata ctcctcagcc agcgcatatt ctttggcttc aaggagttca
    16261 tgttctacga tattttgaat ttcgtaaatc ttaattccct gtggaaagcg actatgaatt
    16321 tctgtaataa ttctctcagt cagatcattg aggcgttttt caaccagggg tgtcacatcc
    16381 ataaccttgt cagctgcctt gtggagagcc ttgtcaatct tgtccacatc aaatacaaca
    16441 cgtctcccat ctcgtttctc gacgaagaga gttggcaaaa ttgtaatttt ttcttctagt
    16501 gcaatcatat gcatgctctt ttctaaaatg ttctttctaa aaagtattat accactctaa
    16561 aaagaaaaat caatatcttg tgttaaaaat cctaaaattt ttaaaaatac acaagatatt
    16621 gatttggtta tttaatttta tagactttaa actctgagta atcagtcttt acttgttggt
    16681 aattttcttt taaaagtgtt tccacttcag accagactac caccttgtca tttaccacaa
    16741 tcaccttagg ttgtttttct ttcaagtcat taagtaactt attacgattt tcctcagttg
    16801 ctgtatagtg caacggggac aaaatcgccg atggcgacaa gcgctcactc ttacgataaa
    16861 gagtcgcagt atcatcccat gcatagatag catcttccgt atttgtctcc tcttttacca
    16921 aatcagcaag acgattacgt tcttgataag gtactggata aaggacaaac ttcatcaaaa
    16981 aaggaacaga caaaagatag acaaacccaa aaactagcag atatagattt cctttgaaga
    17041 aacgactcca taggctaact ggcgtttctc ttcggcttct tctagcacta cgccccctct
    17101 gttgactctt gatattggtt accaataaaa gtaggaaaac agggaagacg accatcaaat
    17161 aagaagcgtg cagaggctct tgtgaaaaga aaagtaaaat caaacctaaa attaccacaa
    17221 gacttgcagg aaccgaaatg acgtatagtt taaagggttt ggattgaaag agacctaaaa
    17281 agatacaaac cacaaatccc aaaccaaggg acaacaagcc ataaaaaaac atattctcta
    17341 aaattttaga agtaaaatca aagcgaatac tgtcaatagg ataacgaata ccactaatcg
    17401 catccccaaa acttcctgtt gcagcactat agtaggcagt tggataaaag acaagtgaaa
    17461 aacctaaagc cactgcaaga aactgataaa acccatgcgc aaagcgtcta tgcccaaggt
    17521 taaagaccaa caagcctaaa ctcactacag caataaacag gagtgatgat aagggagcaa
    17581 agaaaaatcc gcctgccaaa gctaacccaa tccgtacaaa tcccttatca tggcttggat
    17641 tgcttaggta agccgcaact aaactaaagg ctgcgaataa gaaaggaagc gctaaaagag
    17701 tcgcatagcc tccaccaaaa gcaagacctg taactagcat gtaaaaaata gtcaccagat
    17761 gtccagcttg gtctccttgc tctgtcaagg tgtccgctga tctaaaaagg aaaaatcctc
    17821 ctgctaccaa ggctaaccac tcaaagatgg caaagaaaaa tccgccctga ctcacgtaag
    17881 tcagcaaata ataaagcaaa ccttgacttc cataatagtc gctgtaaatc ttccctgtct
    17941 gatgaagcgc ccaacctgca taaaaatcct gcacttcttg tgcactcatt aagtcgagta
    18001 atagcggtac tcctagagtt atccccgtta caagcgtact ccatagtaaa attttcacca
    18061 aaggaagacg acttgattca cgatgatgcg attcttgctc gatttggtat tctagaggtt
    18121 cacgattctc cttatgaact tcttctactc taccatacac actcatatcg tttctcctgt
    18181 tcaatttatc tgtcttagta tatcaaaaag tcctaggatt gtcagcttgc gatggctgtt
    18241 tgagtgattt tttgcatagt ttcacaaagg tttcaatttc ccgaaagcgg tgtaaatgtg
    18301 tctgtttgaa ctcaatcata tcattcactt cttccttagt tagcatgaat tcccctcctc
    18361 tttctttcta ttcgtaaaag acaagaaaaa taggtcgggt ttgtatccta agttctagat
    18421 ttcttataag ataggggcga atagctgggc gatttctttt acaagctttt gataccagct
    18481 cgttttgata gaatgaggat agacttcctg agaatctgca aatatatttc gaaaatctcg
    18541 ggcgatttcc cttatagaag gagttttata gagtaagact gcattttcat aatggtgtac
    18601 caagctccgg tagtcgagat tgattgtccc caccaccgca aaatcttcgt ctaccaacat
    18661 ctgcttacta tgaataaaac ctggactata ctcataaatc cgaacaccag cagaaagaag
    18721 gtcgggataa gctcctctcg tgactaactg aatgaacttc ttatctggta tgtaaggggt
    18781 gataattcga acatcgaccc ctctcatagc tgcatttttg attgtctctg ttaaatcata
    18841 atctataatc aaataaggtg tcgtaatata gaccgattcc gttgcttgat tgattaaact
    18901 ctgataaact tttttcccta cctgcgctcg aaaaattggc ttgggtccac ttccgtatgg
    18961 aatggttaaa ccgtcactcg ggatagaatg attttctaaa tgatattgat caaaatcact
    19021 aatttctcct cgattaatgt accaagtggt caaaaataag cgtgtcaggg cttttactgc
    19081 tagtccgtct aagcgaattc cactatcctt ccaataacca aatctctcga cgtggttaat
    19141 gtactcatct gccagattga ccccaccagt ataggctatc tgaccatcaa caatcaatat
    19201 ttttctatga tctctgttat tataagccac tgtcaaacga ggaataactt tattgaattt
    19261 atgggcctcg atgcccagct gacgaagtcg atgtgcataa tctcctgtta aagtagccat
    19321 acagccgata tcatcataga gcatcttaac ctctacaccc tgagctacct tttgctctag
    19381 tatatctagt atgcgattcc acatcaaacc ttcttctata atgtaatatt ccaagaaaat
    19441 aaatttctca gcctttttaa gatcttctac catctttttc cacatagctt ctccgttagg
    19501 aaaaaatgta gaggcagttt gatcatagat gtcagcattg gtatccatac tcaataagga
    19561 cttgatgact ccataagctg ccttgtcact ttcttttaat ttctctttta gtagctggct
    19621 atttgcttct tggaaatgca tagagcctag cttcttcagt tgtttgattt cttttttgga
    19681 caatcgcctt tcaccaaaca tcagatagag taagggacca aatactggca caaaggctac
    19741 taacaaccag gttaccttat tctcaggagt cgtattacgg ttgactatcg aaatgattgt
    19801 gatgatactc agtagaatga ggacagtaat ccataaaatg ggagccatgc gtcctaaata
    19861 aagaaagaga ccaaaaacaa gacaaagttc aagtagcata atcgaaagac taaagccata
    19921 cttggacatc aataattgaa atttcctata tttcatatcc cctccttgat agtttgaatg
    19981 ctaaaaacaa gtaattgata ctagtataac gcaggtattc ggtagaaggc aagtatttat
    20041 gattattttc taggtaaaag taaaaaggct gaaaaatcca gccctttcta cttgcatagt
    20101 cttatttagt taaaacgatt tggtccgatg ggtctctatc catatcatct acgacgattt
    20161 gattaccgtt tacagtgtaa attttgacat catcgccaat aatcatgcgt tgatttgctg
    20221 aatcaaatgt aacctgtttg actttctgat ccccgtcaga ttcgagctca gtccatgtac
    20281 cagtcgttcc agttaccact aaagtgatac ggtctccgtc atcctgacca gtataagtcc
    20341 catcaatatc ggtcggttga gcaacaggtt ggttttgtac tggagccgct tgattttggt
    20401 tacctcctgc atttgcagta ttggtattct gttgagcagg ttgttgagca ggctgttgga
    20461 cctgctgctg agcaacaggc tgttgaacct gttgagctct ttgtgaacaa gctactaaga
    20521 gactaaaact tgctagagaa gcaagagaaa gtgtgaatct ttttaatttc atgatgaatt
    20581 tcctttctgc taccaattta gagaaatttt ctctaaccag caattcccct agtataacaa
    20641 gttcaaacaa gggggtcaat ttatctgctc acggtccagc aggtagcccc gtacttctga
    20701 gataaaatag agagaccctg taacgaacag caagtcttga gcgtctgccc tttcttcgaa
    20761 actgctgata aattctcggc aagaagaaac tatatcgtaa cctgtcacat ccctttcgtc
    20821 caaagccccc tgatagtcaa agccggtcac cttgagttcc acctgaggca atttttcagt
    20881 caggtaacct aacatccctt gataatcctt ccgtttcaag gctccaaaaa ggatttgagg
    20941 tcgatagcct tcctgctctt tttctttgat aaactcaacc aagcgagtca aggcagggag
    21001 gttatgagca ccatccaagt aaatctgtgg gcgaatacgc tccaagcgac cagcccaatg
    21061 ggtctgttcc aaggcctttc ttacagcctg ttcatcaaca gcttcctttc cttctcccat
    21121 aaaaagaaga aaagtttgca acgccaaggc tgcattctcc tgctgataga ctccttctaa
    21181 gcctatgttc agctgtgaaa aatttagtaa agagcttgaa aaatcaccat tcagcattaa
    21241 aaaatcttga cctgcctgat aaaggttaac agctaaagat tcggcttttt tctgacagac
    21301 aagcctagct tctggaggca atttcgcaat cactgccttc ttaccagcct tgaaaatacc
    21361 agctttctgc tctgcaattg cttctagact atcacccaag gtttcttgat ggtcaagccc
    21421 aatggaggtg atgacagcaa gctctccagt taccacattg gtcgtgtcaa gtaagccacc
    21481 aattcccact tctaataaaa ccaaatccac ctcttgctcc ctaaaataaa gaaaagcaac
    21541 caaggtcagc atttcaaaaa aggacaactg gtcaggagtt tgcagaagcg ttttctccat
    21601 ctccttgacc tgatcagcca aacggataaa gtctgcgtct gctataggtt gcccattaat
    21661 gcagattcgg tcattgatag agacgatatg aggggaggta aaggtcgcaa cttttttgcc
    21721 atgccccata aataattccc tcataaaagc aatggtagat cctttcccat tagtccctgt
    21781 tacgtggata atagggtaag actgctcagg atttcctaac aaatccaccg cttgctgtat
    21841 tcggcccaaa cctgatcgaa aattcaaacc aatccgacta tgaagccatt cttctacttc
    21901 aaacatacac atctccttga caaaagtcca atcaattatc gcattaaagt atggttacta
    21961 ataaaaacaa ggccaggatt ttcgtcccga cctcttacct ggttagctaa taactagcca
    22021 ctatgaatgt gaatatgggc taaaaacatc cactagatgt tccaactctt ccccatttct
    22081 gggagttggg ctgatacagt ctcccagact gtatcactcc tccataaagc tgttgaagac
    22141 ttcttcaatc atgttccatt cgtcttctga gtcttctggg attggttgca attcgccttc
    22201 tgttccatct tcattttcaa tgaatgagta agcttggatt tcaacttgtc cgtcttcgtc
    22261 ttcttctgcg ttaactggta ctagaagaac atagttttta ccaaattctt cttttccatc
    22321 aattgtcaaa aggatttcaa acaaggtttc atttccttgc tcatctacta gtgtgattag
    22381 ttcacgttct tcgtggtcgt ggttatgatc gtgtgacata gcctctcctt tatattaaaa
    22441 ttttctatct aaataatttt gtaaaatcag ctgagctgct aacttatcaa tgactttctt
    22501 gcgcttattg cgactgatat ctgcttgttc aatcaacatg cgctcagcag ccactgttgt
    22561 caagcgttca tcctgatagt ctaatggtaa accaaaaaac tcttctagct ttgctccgta
    22621 ggcttgacta gcttctacgc gcggtccact tgtattgttc atgtttttag gcaagcccac
    22681 tacaaatcgt tccaccttgt aagtatcaac caattcctta acgcggtcaa aaccaaattg
    22741 gccttgttct tcatttatct ggatgatttc aagcccttga gctgtaaaac caagcggatc
    22801 gctaatcgcc acccctaccg tttttgaacc gacgtccaat cccataattc tcataggtta
    22861 tagatcgact ccttgtcctt tgaggtagta gcgaaccaat tcctcaacga tttcatcacg
    22921 ctcatactta cggatttgat ttcgtgcatt attataacga ggaacgtagg cagggtctcc
    22981 actcaatacg taacctacga tttggttaat tgggttgtaa cccttatcgt tcaacgaagc
    23041 ataaacatct gtcaaagttt cgctaatttc ttttttattg gaatcgtcca atttaaaacg
    23101 tactgtttct tcagtaaatc ccattctaac accctctttc cttagaatag taccattata
    23161 gcataattcc ttaccttcta caattcaggc agtctattta tttggatttt ctattgttct
    23221 gtcgcgccat ttgccaatct atctgaaata tatttgcttg gttcattttt caaaagattt
    23281 tccaaaccaa tattcttcag atgttccaac tgggaagcct tcttgacatc cagaacttga
    23341 aaatcaaaac tagtcgttgt ttgaagttcc gttgcgctca atagttttgt ttcaagtttg
    23401 aaacctgcca atttacgagc ttcaatgata gacttatcct tctcctccgc ttcaagaaga
    23461 gctttttgag tttcctccac tccatgttgg tcaatataag tcttcaactc atcagagact
    23521 ggacgttttt gttggatagt tagactcaaa aaagtcttgt ccttgtatgt aatggtttgt
    23581 gtctgctggc taccatcatc tgacttgggc aagaccaaag tcttagttac aactgtattc
    23641 ttctcagcat tttcaataac tggcaatgcc gactgaagcg tatctttttc tgtttttgta
    23701 gctggtccag tttctttttt ctgtccgcaa ccaaccagga caaaaaggaa agctagacta
    23761 acaagaacta tttttttcat ttctttcttc tttctttttg aaattaaaat agaataagac
    23821 tgggaagtgc tcccagcctt gatgtttata gagctgcacg caaacgtgct tctgcatttt
    23881 ctacattacg gacagagcgt ggtaggaagg cacgaatatc gtcttccttg tagccaactt
    23941 gcaggcgttt ttcatctaca aggattgggc tctttaaaat tctcggtgtt tccataatca
    24001 gattgagaac ttcattgaca ctcaaatctt caatatccac tccaagggct ttggcatagc
    24061 gatttttaga cgaaacgatg ctggctattc cgttatctgt tttggttaga atatccagta
    24121 attcttctct cgtaattcct tctttaccaa ggttttgttc tttataactt aactggtggg
    24181 cattgagcca ggtttttgct tttttacagc tagtacaact tgagactgta taaattttaa
    24241 tcatgtacct acccctttcg ctacatgtta ctatcagttt agtctattat accataaaaa
    24301 acatccgact tgcgacctat ttttaat
//
LOCUS       DAVBDR010000027        24188 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.027, whole genome shotgun sequence.
ACCESSION   DAVBDR010000027 DAVBDR010000000
VERSION     DAVBDR010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 24188)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24188)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24188
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.027"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            <1..271
                     /locus_tag="VQ540_001140"
     CDS             <1..271
                     /locus_tag="VQ540_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2544954.1"
                     /translation="FEAWFQKFLLPTLTTPSAIIMDNARFHRMGKLELLCEEFGHKLL
                     PLPPYSPEYNPIEKTWAHIKKHLKKVLPSCCNTFYEALLSCSCFN"
     gene            complement(478..2736)
                     /locus_tag="VQ540_001141"
     CDS             complement(478..2736)
                     /locus_tag="VQ540_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HET2544955.1"
                     /translation="MLCQNCKINDSTIHLYTNLNGKQKQIDLCQNCYKIIKTDPNNSL
                     FKGMTDLNNRDFDPFGDFFNDLNNFRPSSNTPPIPPTQSGGGYGGNGGYGSQNRGSAQ
                     TPPPSQEKGLLEEFGINVTEIARRGDIDPVIGRDDEIIRVIEILNRRTKNNPVLIGEP
                     GVGKTAVVEGLAQKIVDGDVPHKLQGKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEI
                     RKREDIILFIDEIHEIVGAGSASDGNMDAGNILKPALARGELQLVGATTLNEYRIIEK
                     DAALERRMQPVKVDEPTVDETITILKGIQKKYEDYHHVQYTDAAIEAAATLSNRYIQD
                     RFLPDKAIDLLDEAGSKMNLTLNFVDPKVIDQRLIEAENLKSQATREEDFEKAAYFRD
                     QIAKYKEMQKKKITDQDTPIISEKTIEHIIEQKTNIPVGDLKEKEQSQLIHLAEDLKS
                     HVIGQDDAVDKIAKAIRRNRVGLGTPNRPIGSFLFVGPTGVGKTELSKQLAIELFGSA
                     DSMIRFDMSEYMEKHSVAKLVGAPPGYVGYDEAGQLTEKVRHNPYSLILLDEVEKAHP
                     DVMHMFLQVLDDGRLTDGQGRTVSFKDAIIIMTSNAGTGKTEASVGFGAAREGRTNSV
                     LGELGNFFSPEFMNRFDGIIEFKALSKDNLLQIVELMLADVNKRLSSNNIRLDVTDKV
                     KEKLVDLGYDPKMGARPLRRTIQDYIEDTITDYYLENPSEKDLKAVMTSKGNIQIKSA
                     KKAEVKSSEKEK"
     gene            complement(2965..3195)
                     /locus_tag="VQ540_001142"
     CDS             complement(2965..3195)
                     /locus_tag="VQ540_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HET2544956.1"
                     /translation="MESHLVRIINRLEAMANDGGNLKRNFEREGVVVAEVAYSHDEEN
                     GPIFTLRDVEDRETYTFDSIDLIAMEIYELLY"
     gene            3385..4068
                     /locus_tag="VQ540_001143"
     CDS             3385..4068
                     /locus_tag="VQ540_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001011621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET2544957.1"
                     /translation="MNFSFLPKYLPYFNYGAVVTILISICVIFLGTILGVVLAFGQRS
                     KFKPLVWLANLYVWIFRGTPMMVQIMIAFALMHINAPTIQIGILGVDFSRLIPGILII
                     SMNSGAYVSEIVRAGINAVPKGQLEAAYSLGIRPKNAMRYVILPQAVKNILPALGNEF
                     ITIIKDSSLLSAIGVMELWNGATTVSTTTYLPLTPLLFAAFYYLIMTSILTVALKAFE
                     KHMGQGDKK"
     gene            4068..4802
                     /locus_tag="VQ540_001144"
     CDS             4068..4802
                     /locus_tag="VQ540_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HET2544958.1"
                     /translation="MTETLIKIENLHKSFGKNEVLKGINLEIKRGEVVVIIGPSGSGK
                     STLLRSMNLLEEATKGKVIFEGVDITDKKNDLFAMREKMGMVFQQFNLFPNMTVMENI
                     TLSPIKTKGESREVAEKRAQELLEKVGLPDKADAYPQSLSGGQQQRIAIARGLAMEPD
                     VLLFDEPTSALDPEMVGEVLAVMQDIAKSGMTMVIVTHEMGFAREVADRVIFMADGVV
                     VEDGTPEQIFEQTQEQRTKDFLSKVL"
     gene            4956..5813
                     /locus_tag="VQ540_001145"
     CDS             4956..5813
                     /locus_tag="VQ540_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000192112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HET2544959.1"
                     /translation="MTQIIDGKALAAKLQGQLAEKTAKLKEETALVPGLVVILVGDNP
                     ASQVYVRNKERSALAAGYRSEVVRVPETITQEELLDLIAKYNQDPAWHGILVQLPLPK
                     HIDEEAVLLAIDPEKDVDGFHPLNMGRLWSGHPVMIPSTPAGIMEMFHEYGIDLEGKN
                     AVVIGRSNIVGKPMAQLLLAKNATVTLTHSRTHNLAKVAAKADILVVAIGRAKFVTAD
                     FVKPGAVVIDVGMNRDENGKLCGDVDYEAVAPLASHITPVPGGVGPMTITMLMEQTYQ
                     AALRTLDRK"
     gene            5955..6827
                     /locus_tag="VQ540_001146"
     CDS             5955..6827
                     /locus_tag="VQ540_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000864675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HET2544960.1"
                     /translation="MKVINQTLLEKVIIERSRSSHKGDYGRLLLLGGTYPYGGAIIMA
                     ALAAVKSGAGLMTVGTDRENIPALHSHLPEPMAFSLQDQQLLKEQLEKAEVILLGPGL
                     GDNAFGEDLVKQVFAGLKQNQILIVDGGALTILARTSLSFPSSQLILTPHQKEWEKLS
                     GITIEKQKEDATASVLTSFPQGTILVEKGPATRIWEVGQSDYYQLQVGGPYQATGGMG
                     DTLAGMIAGFVGQFRQASLYERVAVATHLHSAIAQELSQENYVVLPTEISRYLPKIMK
                     IICQQERVSKDKLV"
     gene            7109..7792
                     /gene="rpiA"
                     /locus_tag="VQ540_001147"
     CDS             7109..7792
                     /gene="rpiA"
                     /locus_tag="VQ540_001147"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HET2544961.1"
                     /translation="MENLKKMAGIKAAEFVSDGMVVGLGTGSTAYYFVEEIGRRIKEE
                     GLQITAVTTSSVTTKQAEGLNIPLKSIDQVDFVDVTVDGADEVDSQFNGIKGGGGALL
                     MEKVVATPSKEYIWVVDESKLVEKLGAFKLPVEVVQYGAEQVFRHFERAGYKPSFREK
                     DGQRFVTDMQNFIIDLALDVIENPIAFGQELDHVVGVVEHGLFNQMVDKVIVAGRDGV
                     QISTSKKGK"
     gene            7806..9017
                     /locus_tag="VQ540_001148"
     CDS             7806..9017
                     /locus_tag="VQ540_001148"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HET2544962.1"
                     /translation="MSKFNRIHLVVLDSVGIGAAPDANNFVNAGVPDGASDTLGHISK
                     TVGLNVPNMAKIGLGNIPRETPLKTVAAESNPTGYATKLEEVSLGKDTMTGHWEIMGL
                     NITEPFDTFWNGFPEEILTKIEEFSGRKVIREANKPYSGTAVIDDFGPRQMETGELII
                     YTSADPVLQIAAHEDIIPLDELYRICEYARSITLERPALLGRIIARPYVGEPGNFTRT
                     ANRRDLAVSPFSPTVLDKLNEAGIDTYAVGKINDIFNGAGINHDMGHNKSNSHGIDTL
                     LKTMGLAEFEKGFSFTNLVDFDALYGHRRNAHGYRDCLHEFDERLPEIIAAMRENDLL
                     LITADHGNDPTYAGTDHTREYIPLLAYSPAFKGNGLIPVGHFADISATVADNFGVETA
                     MIGESFLDKLV"
     gene            9019..9561
                     /locus_tag="VQ540_001149"
     CDS             9019..9561
                     /locus_tag="VQ540_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1697 domain-containing protein"
                     /protein_id="HET2544963.1"
                     /translation="MTRYALLVRGINVGGKNKVVMAELRQELTNLGLEKVESYINSGN
                     IFFTSIDSKAQLVEKLETFFAVHYPFIQSFSLLSLEDFEAELENLPAWWSRDLARKDF
                     LFYTEGLDVDQVIATVESLELKDEVLYFGKLGIFWGKFSEESYSKTAYHKYLLKVPFY
                     RHITIRNAKTFDKIGQMLKK"
     gene            9577..10386
                     /locus_tag="VQ540_001150"
     CDS             9577..10386
                     /locus_tag="VQ540_001150"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HET2544964.1"
                     /translation="MTFLNKIHETATFLKEKGIAAPEFGLILGSGLGELAEEIENPVV
                     VDYAEIPNWGRSTVVGHAGKLVYGELAGRKVLALQGRFHFYEGNPLEVVTFPVRVMKV
                     LGCEGVIVTNAAGGIGFGPGTLMAISDHINMTGQNPLMGENLDDFGPRFPDMSRAYTP
                     EYRATAHEVAKKLNIKLDEGVYIGVTGPTYETPAEIRSYKTLGADAVGMSTVPEVIVA
                     AHSGLKVLGISCITNFAAGFQEELNHEEVVEVTERVKGDFKGLLKAILAEL"
     gene            10862..11842
                     /locus_tag="VQ540_001151"
                     /pseudo
     CDS             10862..11842
                     /locus_tag="VQ540_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855254.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="discoidin domain-containing protein"
     gene            11867..12379
                     /locus_tag="VQ540_001152"
     CDS             11867..12379
                     /locus_tag="VQ540_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001275913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin"
                     /protein_id="HET2544965.1"
                     /translation="MSAQITINHKKARYVRIELEGYNALSLAEVEVFRFIATNAETAT
                     QVSKPVQPISQTPVKDKTLTIQHSGAYIARYSITWEEVPVDKDGNQVVRSHSWEGNGR
                     NQTAGFVLNLPIKENMRNLRVKIEKKTGLLWNRWQTIYENRPISAQPHRKITHWGTTL
                     NSKVSDDDVL"
     gene            13026..13736
                     /gene="deoD"
                     /locus_tag="VQ540_001153"
     CDS             13026..13736
                     /gene="deoD"
                     /locus_tag="VQ540_001153"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HET2544966.1"
                     /translation="MSIHIAAQQGEIADKILLPGDPLRAKFIAENFLDDAVCFNEVRN
                     MFGYTGTYKGHCVSVMGTGMGMPSISIYARELIVDYGVKKLIRVGTAGSLNEEVHVRE
                     LVLAQAAATNSNIVRNDWPQYDFPQIASFDLLDKAYHIAKKLGMTTHVGNVLSSDVFY
                     SNYFEKNIELGKWGVKAVEMEAAALYYLAAQYHVDALAIMTISDSLVNPDEDTTAEER
                     QNTFTDMMKVGLETLIAE"
     gene            complement(13759..14283)
                     /locus_tag="VQ540_001154"
     CDS             complement(13759..14283)
                     /locus_tag="VQ540_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000684222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topology modulation protein"
                     /protein_id="HET2544967.1"
                     /translation="MKIAIIGYSGSGKSTIAEKLSNYYSIPKLHMDTLQFQPGWQDSD
                     CEWMLTEIKNFLTKHKAWVIDGNYSWCYYQERMQEADQIIFLNFSPLTCLFRAFKRYL
                     KYRGKVRESMAADCPERFEWEFIRWILWDGRSKTQKENYQKLCQEYSHKVTILRNQRE
                     LDQFLDKKRKSYNS"
     gene            complement(14336..14572)
                     /locus_tag="VQ540_001155"
     CDS             complement(14336..14572)
                     /locus_tag="VQ540_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001274003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HET2544968.1"
                     /translation="MANIKSAIKRAELNVKQNEKNSAQKSAMRTAIKAFEANPSEELF
                     RAASSAIDKAETKGLIHKNKASRDKARLSAKLAK"
     gene            complement(14640..15560)
                     /locus_tag="VQ540_001156"
     CDS             complement(14640..15560)
                     /locus_tag="VQ540_001156"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HET2544969.1"
                     /translation="MTNEFLHFEKISRQTWQSLHRKTTPPLTEEELESIKSFNDQISL
                     QDVTDIYLPLAHLIQIYKRTKEDLAFSKGIFLQRESKSQPFIIGVSGSVAVGKSTTSR
                     LLQILLSRTFTDATVELVTTDGFLYPNQTLIEQGILNRKGFPESYDMEALLNFLDRIK
                     NGQDVDIPVYSHEVYDIVPEKKQSVKAADFVIVEGINVFQNPQNDRLYITDFFDFSIY
                     VDAGVDDIESWYLDRFLKMLSLAQNDPDSYYYRFTQMPIGEVESFAHQVWISINLTNL
                     QNYIEPTRNRAEVILHKSKNHEIDEIYLKK"
     gene            15750..16154
                     /locus_tag="VQ540_001157"
     CDS             15750..16154
                     /locus_tag="VQ540_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2544970.1"
                     /translation="MKILKRYILELCFILSFALPFIKGTNADNGRCFVETYYGFTFLM
                     EHAIVTAVFIYSFLIAFLLKKRWAKWIAAGSYCFLVLWIATEGYFFRMSLEDLIRLWT
                     SLEILTQTYQLGFYLNILLGILLIIKYFKVKQ"
     gene            16370..16951
                     /locus_tag="VQ540_001158"
     CDS             16370..16951
                     /locus_tag="VQ540_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HET2544971.1"
                     /translation="MYYAENPDAAHDIHELRVDLLGQKMTFLTDAGVFSKKMVDFGSQ
                     LLLKCLDVNQGETVLDVGCGYGPLGLSLVKVYGVQATMVDINTRALDLARRNAEKNNA
                     KATIFQSNIYEQVEGHFDHVISNPPIRAGKQVVHEIIEKSKDFLETGGDLTIVIQKKQ
                     GAPSAKSKMEDVFGNCEILKKDKGYYILRSVKE"
     gene            16948..18225
                     /locus_tag="VQ540_001159"
     CDS             16948..18225
                     /locus_tag="VQ540_001159"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001202959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HET2544972.1"
                     /translation="MRAVDLIQKKRDGQELTSSEIEWLVEGYVSGTVPDYQMSAFAMA
                     VYFKGMTTREISDLTMNMVKTGQEFDLSAIDGVKVDKHSTGGVGDKVTLILAPLVASF
                     GVPVAKMSGRGLGHTGGTIDKLESIRGYQVERSQEDFIRQVQDIGVSVIGQSDQLVKA
                     DKLLYALRDVTATVDTIPLIASSVMSKKIAAGADAILLDVTVGEGAFMKTVDEARELA
                     QTMVDLGKVVGRKTVAVITDMSQPLGRAIGNRLEILEALEILQGQGRQDITHFICELA
                     QIMLGLANVNKTVEEVHQHLENGQALAKFEEMVQAQGGDLEDLYRPVNVAHVVEIPAQ
                     ETGVISALPAMDFGLYAMRLGAGRAVKSDALDYETGIVFEKKIGDSVQKGEIVAKVYT
                     NEKIPPQLVTDFQKCVKISDEVKKIREIVEIIS"
     gene            18243..18905
                     /gene="deoC"
                     /locus_tag="VQ540_001160"
     CDS             18243..18905
                     /gene="deoC"
                     /locus_tag="VQ540_001160"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HET2544973.1"
                     /translation="MKLNKYIDHTLLKQDAKKKQIDSLLSEAREYDFASVCVNPTWVE
                     HAKKGLEGTDVKVCTVVGFPLGATTSAVKAFETKEAIQNGADEIDMVINVGALKSGNL
                     ALVESDIRAVVEASGDKLVKVIIEACLLTDQEKIVVCQLAQKAGADFVKTSTGFSTGG
                     ATIADVTLMRETVGSDMGVKAAGGARSYADALAFVEAGATRIGTSAGVAILKGELADG
                     DY"
     gene            18892..19281
                     /locus_tag="VQ540_001161"
     CDS             18892..19281
                     /locus_tag="VQ540_001161"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HET2544974.1"
                     /translation="MATTELIELAIETSKHAYVPYSHFPIGAVLVAKDGSVYTGVNIE
                     NASYPLTNCGERTAIFKAISEGQREFSELIVYGQTEKPISPCGACRQVMAEFFEQDLK
                     VTLVAKDKSTVEMTVGELLPYSFTDLN"
     gene            19371..20423
                     /locus_tag="VQ540_001162"
     CDS             19371..20423
                     /locus_tag="VQ540_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family protein"
                     /protein_id="HET2544975.1"
                     /translation="MNKKQWLGLGLVAVAAVGLAACGNRSSRNAASSSDVKTKAAIVT
                     DTGGVDDKSFNQSAWEGLQAWGKEHNLSKDNGFTYFQSTSEADYANNLQQAAGSYNLI
                     FGVGFALNNAVKDAAKEHTDLNYVLIDDVIKDQKNVASVTFADNESGYLAGVAAAKTT
                     KTKQVGFVGGIESEVISRFEAGFKAGVASVDPSIKVQVDYAGSFGDAAKGKTIAAAQY
                     AAGADIVYQVAGGTGAGVFAEAKSLNESRPENEKVWVIGVDRDQEAEGKYTSKDGKES
                     NFVLVSTLKQVGTTVKDISNKAEKGEFPGGQVIVYSLKDKGVDLAVTNLSEEGKKAVE
                     DAKAKILDGSVKVPEK"
     gene            20567..22102
                     /locus_tag="VQ540_001163"
     CDS             20567..22102
                     /locus_tag="VQ540_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000929819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2544976.1"
                     /translation="MAHENVIEMRDITKVFGGFVANDKINLHLRKGEIHALLGENGAG
                     KSTLMNMLAGLLEPTSGEIAVNGQVVNLDSPSKAASLGIGMVHQHFMLVEAFTVAENI
                     ILGSELTKNGVLDIAGASKEIKALSERYGLAVDPSAKVADISVGAQQRVEILKTLYRG
                     ADILIFDEPTAVLTPSEIDELMAIMKNLVKEGKSIILITHKLDEIRAVSDRVTVIRRG
                     KSIETVEIAGATNADLAEMMVGRSVSFKTEKQASKPKEVVLSIKDLVVNENRGVPAVK
                     NLSLDVRAGEIVGIAGIDGNGQSELIQAITGLRKVESGSIELKGDSIVGLHPRQITEL
                     SVGHVPEDRHRDGLILEMMISENIALQTYYKEPHSKNGILNYSNITSYAKKLMEEFDV
                     RAASELVPAAALSGGNQQKAIIAREIDRDPDLLIVSQPTRGLDVGAIEYIHKRLIEER
                     DNGKAVLVVSFELDEILNVSDRIAVIHDGKIQGIVSPETTNKQELGVLMAGGNLGKEK
                     SDV"
     gene            22095..23153
                     /locus_tag="VQ540_001164"
     CDS             22095..23153
                     /locus_tag="VQ540_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2544977.1"
                     /translation="MSKKLQQISVPLISVFLGILLGAIVMWIFGYDAIWGYEELFYTA
                     FGSLRGIGEIFRAMGPLVLIGLGFAVASRAGFFNVGLPGQALAGWILSGWFALSHPDM
                     PRPLMILATIVIALIAGGIVGAIPGILRAYLGTSEVIVTIMMNYIVLYVGNAFIHAFP
                     KDFMQSTDSTIRVGANATYQTPWLAELTGNSRMNIGIFFAIIAVAVIWFMLKKTTLGF
                     EIRAVGLNPHASEYAGISAKRTIILSMIISGALAGLGGAVEGLGTFQNVYVQGSSLAI
                     GFNGMAVSLLAANSPIGILFAAFLFGVLQVGAPGMNAAQVPSELVSIVTASIIFFVSV
                     HYLIERFVKPKKQVKGGK"
     gene            23156..24112
                     /locus_tag="VQ540_001165"
     CDS             23156..24112
                     /locus_tag="VQ540_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2544978.1"
                     /translation="MSIITLLPLLVSSMLIYSAPLIFTSIGGVFSERGGVVNVGLEGI
                     MVMGAFSGVVFNLEFAEQFGAATPWLSLLVAGLVGSVFSIIHAAATVHFRADHVVSGT
                     VLNLMAPALAVFLVKVLYNKGQTDNLSQTFGRFDFPVLANIPVIGDIFFKSTSLLGYL
                     AIAFSFLAWFILFKTQFGLRLRSVGEHPQAADTLGINVYKMRYLGIIISGFLGGIGGA
                     IYAQSISVNFSVTTIVGPGFIALAAMIFGKWNPIGAMLSSLFFGLSQSLAVIGSQLPF
                     LQGVPAVYLQIAPYVLTILVLAAFFGKAVAPKADGINYIKSK"
BASE COUNT         7028 a         4376 c         5497 g         7287 t
ORIGIN      
        1 ttttgaagca tggtttcaga agtttctctt accaacatta accacaccat cggctattat
       61 tatggataat gcaagattcc atagaatggg gaagctagaa cttttatgcg aagagtttgg
      121 gcataaactt ttacctcttc ctccctactc acctgagtac aatcctattg agaaaacatg
      181 ggctcatatc aaaaagcacc tcaaaaaggt attaccaagt tgttgcaata ccttttacga
      241 ggctcttttg tcctgctctt gtttcaattg actatagcag attgaaataa gatgagaaca
      301 aatcgattgg gaaagtaaaa ttaatttcta taaatgtttt agcaattgtt tcgtactatt
      361 tcagattcag tctactatat atcataatgg acaaagggca agctgtcaag aaattacagt
      421 tattttagta aaaaaagaag cagaaaaatt taattttcta ctccttttct ataggattta
      481 tttttctttt tcagaacttt taacttcagc ttttttggca gatttaatct gaatgtttcc
      541 cttgctagtc ataactgctt tgagatcttt ttcgcttgga ttttcaaggt agtagtcagt
      601 gattgtgtcc tcaatatagt cttgaatagt ccgacgaagt gggcgtgctc ccatttttgg
      661 atcataacct aggtcaacca acttttcctt gaccttgtca gttacatcca aacgaatgtt
      721 gttgctagag aggcgcttgt taacatctgc tagcatgagc tcgacaatct gaaggaggtt
      781 atccttgctg agagccttaa attcgataat gccatcaaaa cggttcataa actctgggct
      841 aaagaagtta ccgagttcac cgaggacaga attggtacgt ccttctctag cagcaccaaa
      901 tccaacgcta gcttcggtct ttcctgtacc tgcatttgag gtcatgataa tgatggcatc
      961 cttgaagcta acggtgcgtc cttgcccgtc tgtcaaacga ccatcgtcca agacttgaag
     1021 aaacatgtgc ataacatctg ggtgagcttt ttccacttca tcgagaagga tgagagaata
     1081 tggattgtgg cgaacttttt cagttaattg accagcctca tcatagccaa cataacctgg
     1141 aggagcgccg accaacttag ccacactatg tttttccatg tattcactca tatcaaagcg
     1201 aatcatacta tcagcagaac caaaaagttc gatagccagt tgtttggaaa gttctgtctt
     1261 accgacacca gttggcccaa cgaagaggaa gcttccgatt gggcggttag gggtaccaag
     1321 tccgacacga ttacggcgaa tagccttggc aatcttatcg actgcatcat cttggccaat
     1381 aacatgagac ttgagatctt cggctagatg gatgagttga gattgttctt tctctttcaa
     1441 atcaccaaca gggatattgg ttttctgctc gataatgtgc tcaatagttt tctcgctgat
     1501 gataggagta tcctggtctg tgatcttttt cttttgcatt tccttatact tggcaatctg
     1561 gtcgcggaag taggccgcct tctcaaaatc ttcttctcgt gtagcttgag acttgagatt
     1621 ttcagcctca atcaagcgct gatcaattac tttaggatcc acaaaattca aggtcaagtt
     1681 catcttagaa ccagcttcat ctaggaggtc aatggccttg tcaggcaaga agcgatcttg
     1741 gatgtagcga ttggaaagag ttgcagctgc ttcaatcgca gcatctgtat attgaacgtg
     1801 gtggtaatct tcgtatttct tttgaatccc tttgagaata gtgattgttt cgtccaccgt
     1861 tggttcatcg actttaacag gctgcatacg acgctcgagg gcagcatcct tttcaatgat
     1921 acggtattca ttgagggtag tagcaccgac tagttgcagt tctccacgag caagggctgg
     1981 cttgaggata tttcctgcgt ccatattacc atcactcgca gaaccagcac caacaatttc
     2041 atggatttca tcgataaaga ggatgatgtc ttcacgtttg cgaatttctt ccatgagttt
     2101 ttgcatgcgt tcttcaaatt gtcctcgaat ccccgttcct tgaactaagc taaccacatc
     2161 cagacggatg acttgtttac cttggagttt atgtggcaca tcgccatcga caattttctg
     2221 agctagacct tcgacaacgg ccgtttttcc gacaccaggt tcaccgataa ggacaggatt
     2281 attcttggtt ctacgattga gaatctcgat gacacggata atctcatcgt cgcgcccaat
     2341 aacggggtca atgtctccac gacgggcaat ttcagttaca ttaataccaa attcttccag
     2401 caggcctttt tcttggctag gtggcggagt ttgagcagat ccacgatttt gggaaccata
     2461 accgccgttt ccaccgtaac ctccacctga ttgggttggg ggaataggag gagtattgct
     2521 agaaggtctg aaattgttta gatcattgaa gaaatcacca aagggatcga agtcacgatt
     2581 gttcagatcc gtcatacctt tgaagaggct attgttagga tctgttttga taatcttata
     2641 gcagttttga cagaggtcaa tttgtttttg ttttccattg agattggtgt aaagatgaat
     2701 tgttgagtcg ttaattttac agttttgaca aagcatacat ctacctcatt tctttcttta
     2761 gcctgacttg tttaaaggtc aaaaatagtc aaattctata ctctcattat aacaggattg
     2821 gggtgtaaag caagtaaaaa gattgaagct ttgagaagtt gttacaatga aaatttttgt
     2881 gaatttggac tataaaaaaa tcctatttgt gagacaaaaa ggattttact tagacatgca
     2941 gggacaatcc cagcttgttt tagattagta gagaagttcg taaatttcca ttgcgattaa
     3001 gtcaatgcta tcaaacgtat acgtttcgcg atcttctacg tcacgaaggg taaagattgg
     3061 gccgttttct tcgtcgtggc tgtacgcaac ttctgcaaca acaactcctt cgcgttcaaa
     3121 attacgtttt aaatttccgc catcgtttgc cattgcttca aggcggttga tgattctaac
     3181 caaatgtgat tccattttga ttctccttca tttcttatcg ttactatttt accataaagg
     3241 aggccaactt gactagaaaa aactaagatt tctcgctaat tctgctagtt taaagatttt
     3301 taaataaatt ggataaaaaa tttaaatttt aattcaaaac atgttataat catacagtat
     3361 tctattttag aaagcagtgt gactatgaat ttttcttttt tacctaagta tttaccttat
     3421 tttaactatg gggctgttgt gacgattctt atttctatct gtgttatctt tttgggaact
     3481 attttgggtg ttgtcttggc ttttgggcaa cgttcaaagt ttaaaccgct tgtttggttg
     3541 gccaacttgt acgtttggat tttccgtggg acaccgatga tggttcaaat tatgattgcc
     3601 tttgctctta tgcatatcaa tgctccgact attcagattg gaattttagg tgttgatttt
     3661 tcgcgtctga ttccagggat tttgattatc tctatgaata gtggtgctta tgtttcggag
     3721 attgttcgtg ccggaatcaa tgcggttcca aaaggtcagc tagaggcggc ttattcgcta
     3781 gggattcgtc ctaaaaatgc gatgcgttat gtgattttgc cacaagcagt caaaaatatc
     3841 ttgccagcat tggggaacga atttatcacc attatcaagg acagctccct cttatcagct
     3901 attggggtca tggagttgtg gaatggggct acaacagttt ctacaacaac ctatctacct
     3961 ttaacaccac ttttatttgc agcattttac tacttgatta tgacctctat tctgacagta
     4021 gccttgaaag cttttgaaaa acatatggga caaggagata agaaataatg acagaaacct
     4081 tgataaaaat tgaaaattta cataaatctt ttggaaagaa tgaagtattg aagggcatca
     4141 acctcgagat taaaagagga gaagttgtcg ttatcatcgg tccttcaggg agtgggaaat
     4201 ctaccttgct tcgctctatg aatttgttgg aggaagcaac caaggggaag gttatctttg
     4261 agggagtcga tattacggac aagaagaatg acctgtttgc catgcgtgag aagatgggca
     4321 tggttttcca acaatttaac ctctttccta atatgactgt gatggaaaat attaccttgt
     4381 cacctatcaa gactaaaggt gaaagcaggg aagttgctga gaagagagcc caagagcttt
     4441 tggaaaaagt tggtttgcca gataaggcag acgcttatcc acagagtctg tcgggtgggc
     4501 aacaacaacg gattgccatc gcgcgtgggt tggctatgga accagatgtt ttgctctttg
     4561 acgaaccaac ttcagccttg gatcctgaaa tggtaggtga ggtattggct gttatgcaag
     4621 acattgccaa gtcagggatg actatggtta tcgtaacaca tgagatggga tttgcccgtg
     4681 aggtggcaga tcgtgttatc tttatggcag acggtgtggt tgttgaagat gggacacctg
     4741 agcagatttt tgaacaaacc caagaacaac ggactaaaga tttcttgagt aaggttttat
     4801 aatctatttt aaaatttcaa gacaagatta gtgaaaagtt caaccagagc tttttcttat
     4861 agtttgaaac tataggataa cctaggaaag aagtgttaga gggcactagc agtttttggt
     4921 ataatggaag atatttgaaa gaaaagagaa gtgatatgac acagattatt gatgggaaag
     4981 ctttagcggc caaattgcag gggcagttgg ctgaaaagac tgcaaaatta aaggaggaaa
     5041 cagctctagt gcctggtttg gtagtgattt tggttgggga taatccagcc agccaagtct
     5101 acgttcgcaa caaggagagg tcagctcttg cggctggtta ccgtagcgaa gtagtgcgag
     5161 ttccagagac cattactcaa gaggaattgt tagacctgat tgctaaatat aatcaggatc
     5221 cagcttggca tgggattttg gtccagttgc cattaccaaa acatatcgat gaagaggcgg
     5281 ttttattagc cattgaccca gaaaaggatg tggatggttt ccatccccta aacatgggac
     5341 gtctttggtc tggacatcca gtcatgattc cctcgacacc tgcaggaatt atggaaatgt
     5401 ttcatgaata tgggattgac ttggaaggta aaaatgcggt cgtaatcggt cgttcaaata
     5461 tcgttggaaa acctatggct cagcttcttt tggctaaaaa tgcgacagta accttgaccc
     5521 actcacgaac tcataatctt gccaaggtgg ctgctaaagc agatattctt gtagtcgcaa
     5581 tcggccgcgc caagtttgtg actgctgact ttgtcaaacc aggtgcggtt gtcattgacg
     5641 ttgggatgaa tcgagatgaa aatgggaagc tctgtggaga tgttgattat gaggcagttg
     5701 caccacttgc tagccatatc acgccagtcc ctggaggtgt cggtcctatg accattacca
     5761 tgctgatgga gcaaacttat caagcagcac ttcggacatt ggatagaaaa taagagaagc
     5821 attcgattaa tagagtgtat tttctatagc tatatctaaa atggcagaaa tgaatattaa
     5881 attttagata taagattaca aaaggaggtc tgcgtctcct ttttattgta taataaaagt
     5941 gagaggaaaa aaggatgaaa gtgattaatc aaaccttatt agaaaaagtt attattgaac
     6001 gttctcgttc aagtcataaa ggagattatg gtcgtctgct gctgcttggt ggtacttatc
     6061 cttatggagg tgccatcatc atggctgctt tagcagctgt aaaaagcggt gcaggattga
     6121 tgaccgttgg aacggacagg gaaaatatcc cggctctgca cagccattta cctgagccta
     6181 tggccttttc tcttcaagac cagcaattgt taaaagagca attggagaag gcagaagtta
     6241 tcttgctggg gcctggttta ggagacaatg cttttggaga agatttagtt aaacaggtct
     6301 ttgctggctt aaaacagaat cagattttga ttgtagacgg aggtgccttg accattcttg
     6361 ctaggacaag tttgtcattt ccctcaagcc agcttatcct aactcctcac caaaaagaat
     6421 gggaaaaatt atctggaatt acgattgaaa agcaaaagga agatgcaacg gctagtgttc
     6481 tgacttcctt ccctcaagga acaattttgg tggagaaagg cccagctact cgtatttggg
     6541 aagttggcca atctgattat taccagttac aggttggtgg tccttatcag gcgactgggg
     6601 gaatgggaga tactctggct gggatgatcg caggatttgt aggccaattc cgacaggcca
     6661 gtctctacga gcgtgtggca gtagcgaccc atcttcattc agccatagcc caagaactat
     6721 ctcaagaaaa ttatgtggtc ttaccgacgg aaatcagcag gtatcttccc aaaataatga
     6781 aaattatttg tcaacaagag agggtaagca aagataaact tgtttaaaat agacagataa
     6841 atctacttcc ttctcttaat ttatgattct tgaaatgcgc ctgctttaag gctaaactag
     6901 acgtatcaaa gttaagagtt tgtttttgta actggaaaga gatgaacaaa tcaaatacat
     6961 aaaagataaa ctcattttta ttcgttttgt aaaaataaaa tgcatatttt taaagaaaga
     7021 ttgatgaaaa atgtagattt gatgttttta cttgaataaa aagcggtttc atagtaaaat
     7081 aagaactgag aatgatggag gtaaatcggt ggaaaatctg aagaaaatgg caggtatcaa
     7141 ggctgctgag ttcgtgagcg atggaatggt cgttggactt ggaacaggct cgactgccta
     7201 ttattttgtc gaagaaatcg gtcgtcgtat caaggaagaa ggattgcaga ttacagctgt
     7261 aacaacttct agtgtgacca ctaaacaggc agaaggcctt aatatcccgc tcaagtctat
     7321 tgaccaagta gactttgtcg atgtgacggt tgatggcgcg gatgaagtgg atagtcagtt
     7381 taatggaatc aaaggcggtg gtggtgccct tctcatggaa aaggtggtcg caacaccatc
     7441 aaaagaatac atttgggtgg tggatgaaag caagctggtc gaaaaactag gtgcttttaa
     7501 attgccagta gaagtggttc agtatggtgc agagcaggtc tttcgtcatt ttgaacgagc
     7561 tggctacaaa ccaagtttcc gtgaaaaaga cggtcaacgt tttgtgacgg atatgcagaa
     7621 ttttatcatt gacctcgcct tggatgtcat tgaaaatcca attgcttttg gacaagaatt
     7681 ggaccatgtc gttggtgttg tggagcatgg tttattcaac caaatggtgg ataaggtaat
     7741 cgttgctgga cgagatggag ttcagatttc aacttcaaaa aaaggaaaat agaagggggc
     7801 ataagatgtc taaatttaat cgtattcatt tggtggtact ggattctgta ggaatcggtg
     7861 cagcaccaga tgctaataac tttgtcaatg caggggttcc agatggagct tctgacacac
     7921 tgggacacat ttcaaaaaca gttggtttga atgtcccaaa catggctaaa ataggtcttg
     7981 gaaatattcc tcgtgaaact cctcttaaga ctgtagcagc tgaaagcaat ccaactggat
     8041 atgcaacaaa attagaggaa gtatctcttg gtaaggatac tatgactgga cactgggaaa
     8101 tcatgggact caacattact gagcctttcg atactttctg gaacggattc ccagaagaaa
     8161 tcctgacaaa aatcgaagaa ttctcaggac gcaaggttat tcgtgaagcc aacaaacctt
     8221 attcaggaac ggctgttatc gatgattttg gaccacgtca gatggaaact ggagagttga
     8281 ttatctatac ttcagctgac cctgttttgc agattgctgc ccacgaagac attattcctt
     8341 tggatgaatt gtaccgtatc tgtgaatacg ctcgttcgat tacccttgag cgtcctgccc
     8401 ttcttggtcg catcattgct cgcccttatg taggtgaacc aggtaacttc actcgtacgg
     8461 caaaccgtcg tgacttggct gtatctccat tttccccaac tgttttggat aaattgaatg
     8521 aggctggtat cgatacttat gctgtgggta aaatcaacga tatctttaac ggtgctggta
     8581 tcaaccatga catgggtcac aacaagtcaa atagtcatgg aattgataca ctattgaaga
     8641 ctatgggact tgctgagttt gaaaaaggat tctcattcac aaacctagtt gactttgatg
     8701 ccctttacgg ccatcgtcgt aatgctcacg gttaccgtga ttgcttgcat gagtttgatg
     8761 aacgcttacc tgaaattatc gcagctatga gagagaatga ccttctcttg attactgcgg
     8821 accatggaaa tgacccaacg tatgcaggaa cggatcacac tcgggaatat attccattgt
     8881 tggcctatag ccctgccttt aaaggaaatg gtctcattcc agtaggacat tttgcagata
     8941 tttcagcgac tgttgccgat aactttggtg tggaaactgc tatgattggg gaaagtttct
     9001 tagataaatt ggtataagat gacgcgctat gctttgctgg tgagaggtat caatgttggt
     9061 ggtaagaata aggtcgtcat ggcggagctt cgtcaagaat tgacaaactt gggactggaa
     9121 aaggttgaga gctacatcaa tagtggcaat attttcttta cttcgataga ttccaaagcc
     9181 caattggttg aaaagctaga gactttcttt gcagtccatt atccatttat tcagagcttt
     9241 tctttactga gtctagagga ctttgaggcg gaacttgaaa atctaccagc ttggtggagc
     9301 agagacttgg cacgaaaaga ttttctcttt tacactgagg gtttggatgt ggaccaagtc
     9361 atcgcgacag ttgaaagttt agagctgaaa gatgaagtgc tttattttgg aaaacttggg
     9421 attttctggg ggaaattttc tgaagaatcc tattctaaga ctgcctatca taagtacttg
     9481 ctgaaggtgc ctttctaccg ccacattact attcgtaatg ctaaaacctt tgacaaaatt
     9541 ggtcaaatgc taaaaaaata ataaaggaga cacacaatga catttttaaa caaaatccat
     9601 gaaactgcta ctttcctgaa agaaaaggga attgcagccc ctgagttcgg tctaatcctt
     9661 ggatcaggac ttggagaatt ggcagaagaa atcgaaaatc cagttgtagt agactatgct
     9721 gagattccaa actggggccg ttcaacagta gtcggtcatg ctggtaaatt ggtatatggt
     9781 gaactggcag gtcgcaaggt cttggctctt caagggcgtt tccatttcta tgaagggaat
     9841 cctctggaag tggtgacttt cccagttcgt gtgatgaaag ttcttggatg tgaaggtgtt
     9901 attgtaacca atgcagctgg cggtatcgga tttggtcctg gtaccttgat ggctatctca
     9961 gaccatatca acatgacggg gcaaaatcca ttgatgggtg aaaacttgga tgactttggc
    10021 ccacgtttcc cagatatgtc tagggcctac acaccagaat accgtgccac tgcccatgaa
    10081 gtggctaaaa aacttaatat caagcttgat gaaggtgtct atatcggagt tactggtccg
    10141 acttatgaaa caccagcaga aattcgttcc tataagacac tgggagcaga tgcagttggt
    10201 atgtctacgg ttcctgaagt tatcgtggca gcccactctg gcttgaaagt tctgggaatt
    10261 tcatgtatca ctaactttgc ggccggtttc caagaagaac tcaatcacga agaagttgta
    10321 gaagtgactg aacgtgttaa aggtgatttc aaaggcttgc ttaaagcgat tcttgctgaa
    10381 ttgtaagaaa aaagatttaa aagggggagt gcctctgttt tttcaggatt gactgcctat
    10441 ccggattaaa gaagaaacag aggaatacta tgagcttctt cctgctctta taactgaaag
    10501 aagcggaaga ataggtatgt ctgatctgat agccagcatt gtgaaagaca agattctagg
    10561 atactagcat tagcttccta gccaagcaga ctagtatgat aaggagagat gagaatgaat
    10621 tgactttctg aatttctcag tcttatcata tatagcacaa tgagatttcg cttgagtctg
    10681 cttgtaaata aacgaaaaga aagataagaa ataatgaaaa ttggtcaacg aattatgcgc
    10741 tttggcataa aaaattaagt atcggagttg tatctgttgt agtcggcttt gatttctagc
    10801 tccagctgga atttcagcca atgaagtaaa gcaagatgta acatctgaag tggtaatagg
    10861 tgtgctagat tctaaggagg aattgaaaga gtcagaaaat gatgctccaa aactagaaac
    10921 tcctcttaga gaggagccaa gactagctcc tcaaacgctt ccggaagcaa gtgaagttct
    10981 tgaaaacaaa agggaagagt caaaagtaga gataacataa ccagctcaag cggatgatat
    11041 ccgcaaggtt gttggggaat tagccaagga tataagtatt actaagttgt atatgacagg
    11101 tcattctctt ggatgttacc tagctcagat tgcagcggtt gaagcttacc aaaaatatcc
    11161 tgatttttat aaccatgtat tgaggaaagt gacaactttc agtgctccta aagtgattac
    11221 ttccagaact gtttggaatg ctaagaatgg tttctgggat gttggtttgg aaagtcgtaa
    11281 attagctgtt agtggaaaaa ttaagcatta tgtggttgat aatgacaatg ttgtgactcc
    11341 cttgattcat aataatcgtg atattgttac atttacaggt aattcacgct ttaaacaccg
    11401 ttctcgtggc tattttgaaa gtccaatgaa tgatattcct aactttaata ttggtaaaca
    11461 agctaccttg gataaacatg gttatcgtga tccgaaattg gataaagtgc gattctttaa
    11521 gaaacaggct ctgcctcgat cttctagtca accaagcgct gaaccaatgg aaaatattgc
    11581 cttaggaaaa caggttactc aaagttcgac agctttcgga ggagatgcta gaagagctgt
    11641 ggatggcaaa gtcgatggta actatggtca caattctgtc actcatacaa acttccaatc
    11701 taagccttgg tggcaagtag atttggctaa agaagaaacc attcgccaaa tcaatattta
    11761 caaccgaaca gacactgccc aggatagatt ggcaaacttt gatgtcattc ttttagacag
    11821 ttctggtaaa gaaattgagt gaaaacgtat aatatctcct aaagatgtgt cagcacaaat
    11881 tacgattaac cataaaaaag cgcgctatgt tcggattgag ctagaaggct ataatgccct
    11941 cagtcttgca gaagttgaag ttttccgctt tatagctacg aatgctgaaa cggcgacaca
    12001 agtttctaag ccagttcaac caatcagtca gactcctgtg aaagataaaa cattgacaat
    12061 tcaacacagt ggagcttaca ttgcccgcta ctccataact tgggaagaag ttccagtaga
    12121 taaagatgga aaccaagttg ttcgtagtca ttcttgggaa ggaaacggtc gcaaccagac
    12181 tgcgggtttt gtcctcaacc tcccaatcaa agaaaatatg agaaatctgc gagttaagat
    12241 tgagaaaaag acgggcctac tatggaatag atggcaaaca atctatgaaa acagaccaat
    12301 ttcagctcaa ccccaccgta aaattaccca ttggggtacg acattgaatt ccaaggtgag
    12361 tgacgatgat gtcttgtaat ctgatggtac aatgacagtt agtttgtcta gtttataaga
    12421 aagtactacc tgagcttgaa tagaactcag gtagctctct gtgaaagaac aaaattaata
    12481 ctcaatgaaa atcaaagagc aaactaggaa actagccgca ggttgctcaa agcactgctt
    12541 tgaggttgta gataagactg acgaagtcag tcacatatat aatccaaggc gacgttgacg
    12601 tggtttgaag agattttcga agagtataaa cagaaaggta gagcgcgtgt tctaatttga
    12661 acacgagtag aaaacttttc taaaaacaaa aacgaaagga tgggtaaact gtattcgctg
    12721 aactgaatac gggcgactct cctctaaatc aaaattaaga aaggaattga ccccacccta
    12781 aaagtagtgg gaaaaagata gttggtctag cgagcatcgc tcactgcgcc caactcctat
    12841 tttcccttcg ctttttgatg ggtttggtat ctttctcaat ataaaataaa gaaaggtaga
    12901 gcgtgtgttt tgatttgaac acgagcggaa aactcggaaa atagataatc tgactgaaaa
    12961 atcaggattt ctcgtcaggt tcctaatttt cagtcgtttt cttctcgctc tttgtatcat
    13021 aaattatgtc tatccatatt gctgctcagc agggtgaaat tgctgataaa attcttcttc
    13081 ctggggatcc tcttcgtgct aagtttattg cggagaattt ccttgatgat gctgtttgtt
    13141 ttaacgaagt gcgtaacatg tttggttaca ctggtactta caagggtcac tgtgtatctg
    13201 tcatgggaac tgggatggga atgccatcta tttcgattta tgcgcgtgag ttaatcgtag
    13261 actacggtgt gaagaaattg attcgtgtgg gaactgcagg ttctttgaat gaagaggttc
    13321 atgttcgtga attagttttg gcgcaggcgg ctgcaaccaa ctcaaacatc gttcgtaatg
    13381 actggccaca gtacgatttt ccacaaattg ctagctttga tttgcttgat aaagcctacc
    13441 atatcgccaa aaaacttggt atgactactc acgttgggaa cgttttgtca tctgatgtct
    13501 tttactcaaa ttactttgaa aagaatatcg agcttggtaa atggggagtc aaggctgtgg
    13561 aaatggaagc agcagctctt tactatcttg ctgcccaata ccatgttgat gcgctagcta
    13621 tcatgaccat ctctgatagc ttggtcaatc cagacgaaga cacaactgca gaagaacgtc
    13681 aaaatacctt cactgatatg atgaaggttg gtttggaaac cttgattgca gaataattat
    13741 agccaaaaag gaagcccttt atgaattgta ggacttcctt ttcttatcca gaaattgatc
    13801 tagctctctc tgatttcgaa gaatagtgac tttatgtgaa tattcttggc aaagtttttg
    13861 gtaattttct ttttgagttt tgctacgccc atcccaaaga atccatctga taaactccca
    13921 ctcaaagcgt tcagggcaat ctgccgccat actttctctg acttttccac ggtatttaag
    13981 ataacgctta aaggctctaa agagacaggt caatggcgaa aaattgagaa agatgatttg
    14041 gtcagcttct tgcattcgtt cttggtagta gcaccaagaa taattaccat cgatgaccca
    14101 agctttatgc ttggtgagaa agttttttat ctcggttaac atccattcgc agtcactgtc
    14161 ttgccaacca ggttgaaatt ggagtgtgtc catgtgcagt tttggaatgg agtagtagtt
    14221 agataacttt tctgctatag ttgacttacc agaaccagaa tatccgataa ttgcgatttt
    14281 cattttctac tttttcctat ttggagacaa aaaaacagcc tctatggact gtttcttatt
    14341 tagcaagttt agctgaaaga cgagctttat cgcggcttgc tttgtttttg tgaatcaaac
    14401 ctttagtttc tgctttatcg atagctgagc tagcagcacg gaaaagttct tcagatgggt
    14461 ttgcttcgaa agcttttata gcagtacgca tagctgattt ttgagctgag ttcttttcgt
    14521 tttgtttaac gttcaattca gcgcgtttga tagctgattt aatgtttgcc aatgttctta
    14581 cctccatatt tactaactat accattatat atgaaaactt acgttttgac aagggaaaat
    14641 tactttttta agtaaatttc atcgatttca tggttcttgc ttttatgaag aatcacttct
    14701 gcacgatttc tggttggttc aatataattt tgcagatttg tgagattgat actgatccag
    14761 acctgatggg caaaggactc cacttcccca atcggcatct gagtaaaacg ataatagtag
    14821 ctatcagggt cgttttgggc taggctcagc attttcaaga aacggtccag ataccaactt
    14881 tcaatatcat ccactccagc atctacatag atggaaaagt caaagaagtc agtgatatag
    14941 agacgatcgt tttgtggatt ttgaaagaca ttaattccct caacaattac aaaatcagca
    15001 gctttgacac tttgtttctt ttcgggtacg atgtcgtaaa cttcatgaga atagacagga
    15061 atatctacat cttgtccatt tttgatgcgg tccaagaagt tgagaagagc ttccatatca
    15121 tagctttcag gaaatccttt acgatttaaa atcccctgct caatcaaggt ttgattggga
    15181 tagagaaaac catcagttgt aaccaactca accgtagcat ctgtaaacgt acgggacagt
    15241 aggatttgaa gtaggcgact ggttgtggat tttccaacgg caacactccc agaaacccca
    15301 ataataaaag gttgagattt actttcacgt tggaggaaaa ttccttttga aaaggctaaa
    15361 tcttccttag ttcgcttgta aatctgaatc agatgagcca aggggagata gatatctgta
    15421 acgtcttgga gactgatttg gtcattaaaa ctcttgatag attccaattc ttcttctgtc
    15481 aaaggaggtg ttgtctttcg atgtaaagat tgccaagtct ggcggctgat tttttcaaaa
    15541 tgtaaaaatt cgttggtcat ttgttttccc ctagatattt tgtctatcat accataaaaa
    15601 gctaaaaaaa taaagcggtt tcttgaatgt ggtaagtcaa tggtatatag tataagtgat
    15661 caatttattg atgaaatagg agatagattc tactgattta taagcttata aagggggctt
    15721 tttagttcac aacttatagg aggtgtacta tgaaaatctt aaaacgttac atattggaac
    15781 tctgttttat tttaagtttt gctttacctt ttataaaagg aaccaatgca gataatggta
    15841 gatgctttgt ggaaacctat tacggtttta cttttttgat ggaacatgct attgtaacag
    15901 ctgtctttat ctattcgttt ttaattgctt tcttactaaa aaaacgatgg gcgaaatgga
    15961 ttgctgctgg tagttattgc tttttagtcc tatggattgc gacagagggt tatttcttcc
    16021 gcatgtcact agaagatttg atacgacttt ggacaagttt ggaaatcctg acacaaacgt
    16081 atcagttggg cttttatcta aacattttgt taggaatttt gttgataata aagtatttta
    16141 aggttaagca atagaaataa taatctgcct gattatagat gataaacttt ttgtttttat
    16201 ctggactgtg atatttatag ttctaaatgg tttattattt ataagtgttg aaagagattg
    16261 aagaaaatgg cttcgtgact tgctttcttc ggtctttttc gttttattat caatttgtaa
    16321 acgatttaca atttgagtca aattatggta aaatagtgtc atgagtaaaa tgtattatgc
    16381 agaaaatcct gacgctgctc acgacattca tgagttgaga gtggacttgt tgggacaaaa
    16441 aatgactttt ttgacagatg cgggtgtttt tagcaagaaa atggttgact ttggaagtca
    16501 actcttgctc aagtgtctgg atgtcaacca aggagagaca gtcctagatg taggctgtgg
    16561 ttatggtcca ttaggtttgt ccttggtcaa ggtttacgga gttcaggcga ccatggttga
    16621 tattaacact cgtgccttgg atttagctcg gagaaatgct gaaaaaaata atgcaaaagc
    16681 gacgattttc cagtccaaca tctatgaaca agttgaagga cattttgatc atgtcatttc
    16741 caatcctcct atccgtgcgg gcaagcaagt cgttcatgaa atcattgaga aaagtaaaga
    16801 tttcttggaa actggtgggg atttgacaat cgtcatccag aaaaaacaag gggctccaag
    16861 tgctaagtcc aagatggagg atgtgtttgg taattgtgaa atccttaaaa aagacaaagg
    16921 atactatatc cttagaagtg tgaaagaatg agagcagttg atttaataca aaaaaaacga
    16981 gacggtcaag aactgacttc aagtgaaatt gaatggctgg tagaaggcta tgtgtcagga
    17041 actgttcctg attatcagat gtctgccttt gctatggctg tttattttaa aggaatgacg
    17101 actcgtgaaa tttctgattt aacgatgaat atggttaaga ctgggcaaga gtttgacctg
    17161 tcagccattg atggtgtgaa agttgacaag cattctactg gtggtgtcgg cgataaggta
    17221 accttgattt tagctcctct tgttgctagc ttcggtgtgc ctgtagcaaa aatgagtggt
    17281 cgtggtcttg gccatacagg cggaacaatt gataaattgg agtccattag gggctatcaa
    17341 gtagaacgta gtcaagagga ttttattcgt caggttcagg atattggagt atctgtcatt
    17401 gggcaatcag accagctggt caaagcagat aagcttctct atgcccttcg tgatgtgacc
    17461 gcaactgtcg acacgattcc tttgattgcg agttcggtga tgagcaagaa aattgcggca
    17521 ggggcggatg ctattttgct agacgtgact gtcggtgagg gtgccttcat gaagacggtt
    17581 gatgaggcgc gtgagttggc tcaaactatg gtagatcttg gtaaggttgt tggacggaag
    17641 acagtagcag tgattacgga tatgagccag cctttgggac gagcgattgg aaatcgtctg
    17701 gaaatacttg aagcattgga gattttgcaa ggtcaaggac gtcaggatat tacccacttt
    17761 atttgtgaat tggctcaaat tatgcttggt ttggcaaatg ttaacaagac tgttgaagaa
    17821 gttcaccaac atcttgagaa tggtcaagca ctggctaagt ttgaggaaat ggtgcaagcc
    17881 caaggtggag acttggaaga cctctatcgt cctgtaaatg tagctcatgt ggtggaaatc
    17941 cctgctcagg aaacgggtgt catttcagct cttccagcta tggactttgg tctttatgcc
    18001 atgaggctgg gggctggtcg tgcagttaag tctgatgcct tggactatga aacaggaatt
    18061 gtttttgaaa agaagattgg agactccgtt caaaagggtg aaattgttgc aaaagtatac
    18121 acaaatgaaa aaattccacc tcaactagtt acagatttcc aaaaatgtgt taaaataagt
    18181 gatgaagtga aaaaaatccg tgaaattgta gaaatcatct cctaaatgga gggaaaaccg
    18241 aaatgaaatt aaataaatat atagatcata cgcttttaaa acaagatgca aagaaaaaac
    18301 aaattgatag tttgttgtct gaggctagag agtatgactt tgccagtgtt tgcgttaatc
    18361 cgacctgggt tgaacatgct aaaaaaggac ttgaaggcac agatgttaag gtttgcacgg
    18421 tagtaggttt ccctttggga gcaacaactt cagccgtgaa agcatttgag acaaaagaag
    18481 ctatccaaaa tggtgcagat gagattgata tggtgatcaa tgttggagct ctcaaatcag
    18541 gtaatttagc cttggttgag tcagatattc gcgcagtagt ggaagcaagt ggtgataagt
    18601 tagtgaaagt cattattgaa gcttgccttc tgacagacca agaaaaaatt gttgtttgcc
    18661 aattggccca aaaagctggg gctgactttg ttaaaacatc tactggtttt tcaactggtg
    18721 gtgctacgat agcagatgtt acattaatgc gtgaaacagt tggatctgat atgggagtca
    18781 aggctgctgg tggagctcgt tcttatgcag atgctcttgc ctttgtcgaa gcaggtgcga
    18841 cccgtatcgg aacgtcagct ggggtagcta ttttaaaagg agaattggca gatggcgact
    18901 actgagttga ttgaactggc aattgaaacc agcaaacatg cctatgtccc ctattctcac
    18961 tttcctatcg gagcagtttt agtagccaaa gacggaagtg tttacacggg agtgaatatc
    19021 gaaaatgcta gctatccttt gaccaattgc ggtgagagaa cagctatttt taaggctata
    19081 tctgaaggcc aaagagaatt ttcagaattg attgtctatg gtcaaactga aaaaccgatc
    19141 tcgccatgtg gtgcttgtcg ccaagtgatg gctgaatttt ttgaacaaga tctaaaagtg
    19201 accttagtcg caaaagataa atcgacggtc gagatgacgg tcggggaatt acttccatac
    19261 tcttttacag acttaaacta gtctgagtcg ctctctgagt ggcacggtcc ttgtggccaa
    19321 ccaatccata cttgcaacat cgttgcacat cttatttagg aggttcagta atgaacaaga
    19381 aacaatggct aggtcttggc ctagttgcag tggcagcagt tggacttgct gcatgtggta
    19441 accgctcttc tcgtaacgca gcttcatctt ctgatgtgaa gacaaaagca gcaatcgtca
    19501 ctgatactgg tggtgttgat gacaaatcat tcaaccaatc agcttgggaa ggtttgcagg
    19561 cttggggtaa agaacacaat ctttcaaaag ataacggttt cacttacttc caatcaacaa
    19621 gtgaagctga ctacgctaac aacttgcaac aagcggctgg aagttacaac ctaatcttcg
    19681 gtgttggttt tgcccttaat aatgcagtta aagatgcagc aaaagaacac actgacttga
    19741 actatgtctt gattgatgat gtgattaaag accaaaagaa tgttgcgagc gtaactttcg
    19801 ctgataatga gtcaggttac cttgcaggtg tggctgcagc aaaaacaact aagacaaaac
    19861 aagttggttt tgtaggtggt atcgaatctg aagttatctc tcgttttgaa gcaggattca
    19921 aggctggtgt tgcgtcagta gacccatcta tcaaagtcca agttgactac gctggttcat
    19981 ttggtgatgc ggctaaaggt aaaacaattg cagccgcaca atacgcagcc ggtgcagata
    20041 ttgtttacca agtagctggt ggtacaggtg caggtgtctt tgcagaggca aaatctctca
    20101 acgaaagccg tcctgaaaat gaaaaagttt gggttatcgg tgttgatcgt gaccaagaag
    20161 cagaaggtaa atacacttct aaagatggca aagaatcaaa ctttgttctt gtatctactt
    20221 tgaaacaagt tggtacaact gtaaaagata tttctaacaa ggcagaaaaa ggagaattcc
    20281 ctggcggtca agtgatcgtt tactcattga aggataaagg ggttgacttg gcagtaacaa
    20341 acctttcaga agaaggtaaa aaagctgtcg aagatgcaaa agctaaaatc cttgatggaa
    20401 gcgtaaaagt tcctgaaaaa taatggatgg aagtcatttc ttaggaagcg gccaagggcc
    20461 gcttttttaa gagttgagac aaagtcattt tgtctcagta aagcttgcta ctagacaaac
    20521 tagcaagttt tattgaaata aaataagact ctgaaaggaa gagcacatgg cacacgaaaa
    20581 tgtcattgag atgcgtgata ttaccaaggt gtttggtgga tttgttgcca acgacaaaat
    20641 caacttgcac ctacgaaaag gtgaaattca tgcactttta ggagaaaatg gggctggtaa
    20701 gtccacgcta atgaacatgt tagcaggcct tcttgaacca actagtggtg aaatcgcggt
    20761 caacggtcaa gttgtcaatc tcgactcccc atctaaagca gctagcttgg gaatcgggat
    20821 ggttcaccag cactttatgt tggttgaagc cttcacagtg gctgaaaaca tcattttagg
    20881 tagtgaattg actaaaaatg gtgtgctaga tatcgctgga gctagcaaag aaatcaaggc
    20941 tctttctgaa cgttatggct tagctgttga cccttctgcc aaggtagcag atatctcagt
    21001 tggagcccaa caacgtgtag aaattttaaa aacactttat cggggggctg atatccttat
    21061 ctttgacgaa ccaacggctg ttttgactcc atcagaaatt gatgagttga tggctattat
    21121 gaaaaatctt gtcaaagaag gaaaatcaat tatcttgatt acccacaaat tggatgaaat
    21181 tcgcgcagtt tctgaccgtg ttacagttat ccgtcgtggg aaatcaattg aaaccgttga
    21241 aattgcaggg gctaccaatg ctgatttggc ggaaatgatg gtaggacgtt ctgtttcctt
    21301 taaaacagag aagcaagcct ctaaaccaaa agaagtggtt ttgtctatca aagatttggt
    21361 ggtcaatgaa aaccgtggtg ttccagctgt taaaaatctg tccttggatg ttcgtgctgg
    21421 agagattgtt ggtattgcgg ggattgatgg aaatggtcag tctgaactga ttcaagccat
    21481 tacaggtctt cgtaaggttg aatctggtag cattgagcta aaaggagatt caattgtagg
    21541 cttgcaccca cgtcagatta cagaactaag tgttgggcac gttccagaag accgtcaccg
    21601 tgatggcttg attttggaaa tgatgatatc tgaaaatatt gcccttcaaa cctactataa
    21661 agaaccacat agtaaaaatg gaattttgaa ttattcaaat attacttctt atgctaaaaa
    21721 gctgatggaa gagtttgatg ttcgcgctgc cagtgaatta gttcctgcag ctgcactctc
    21781 aggaggaaat caacaaaaag caattattgc tcgtgaaatt gatcgagatc ctgatctcct
    21841 tatcgttagc cagccaactc gtgggttgga tgtcggtgcc attgagtata tccacaaacg
    21901 cttgattgaa gagcgtgata atggcaaggc tgtccttgtt gtcagctttg aattggatga
    21961 gattttaaac gtctcagacc gtattgccgt tatccacgat ggtaagattc aaggtattgt
    22021 atcaccagaa acaaccaata aacaagaact tggtgtcttg atggctggtg gaaacttggg
    22081 aaaggagaag agtgatgtct aaaaaattac aacaaatttc ggttcccttg atttctgtat
    22141 ttctaggaat tttactcgga gccattgtca tgtggatctt cggttatgat gctatttggg
    22201 gctacgaaga attgttctat acagcctttg gcagtctgcg tgggattgga gaaatcttcc
    22261 gtgctatggg tcctctggtc ttgattggtc ttggttttgc ggttgccagt cgagctggtt
    22321 tctttaacgt cggacttcct ggtcaggctt tggcaggttg gattctcagt ggttggtttg
    22381 cgctgtcgca tccagatatg ccccgtccct tgatgattct agcaaccatc gtgattgcct
    22441 tgattgctgg tgggattgtc ggagcgattc caggtattct tagggcctat ctagggacgt
    22501 cagaggttat tgtaaccatc atgatgaact acattgtctt gtatgtaggg aatgccttta
    22561 tccatgcttt ccctaaagac ttcatgcaaa gtacagattc gaccattcgt gttggggcta
    22621 atgcaaccta tcagacacct tggttggctg agttgactgg taactcacgg atgaatattg
    22681 gtattttctt tgccatcatt gccgttgcag ttatttggtt catgctcaag aaaacaactc
    22741 ttggttttga aatccgtgca gttggtctta atccacatgc ttcagaatat gctggtattt
    22801 ctgccaagcg gactattatc ctatctatga ttatttcagg tgccttggca ggtcttggtg
    22861 gagctgttga aggtttggga accttccaga acgtctatgt tcaaggttcg tcattagcta
    22921 tcggatttaa cggaatggcg gttagtttgc ttgcggccaa ctcaccaatt ggtatactct
    22981 ttgcagcctt cctatttggc gttctccaag ttggggctcc tggtatgaat gcggcgcagg
    23041 taccatctga gcttgtcagc attgtaacag cgtctattat cttctttgtc agtgttcatt
    23101 accttatcga acgctttgtc aaaccgaaaa aacaagttaa aggaggtaag taaagatgtc
    23161 tattataacc ttgctccccc tcttggtgtc ttctatgctg atttactcag cacctctcat
    23221 ctttacaagt atcggtggtg ttttctctga acgtggtggt gtggtaaacg ttggccttga
    23281 aggaattatg gttatgggtg ccttttctgg agttgtcttt aaccttgaat ttgcagaaca
    23341 atttggagca gcaactccat ggctatcctt gcttgtagca ggattggttg gtagtgtttt
    23401 ctctatcatc cacgcagcag cgacggttca tttccgtgca gaccatgttg tcagcggtac
    23461 ggtattgaac ttgatggcgc ctgccttggc tgttttctta gttaaagttc tttataacaa
    23521 aggacaaacc gacaacctaa gtcaaacttt tggacgcttt gatttcccag tcttggcaaa
    23581 tatcccagtg attggtgata tcttcttcaa gtcaactagt ctacttggtt atctggcgat
    23641 tgccttctca ttccttgctt ggtttattct ctttaagact caatttggtc ttcgtctccg
    23701 ctctgtcggt gaacatcctc aagcagcgga taccttggga atcaacgtct acaagatgag
    23761 atatttaggg attattattt caggttttct aggtggaatt ggcggagcga tttatgcgca
    23821 atcaatctca gttaacttct cagtgacaac tattgttgga cctggattta tcgcccttgc
    23881 tgcgatgatc tttgggaaat ggaatccaat cggtgctatg ctttctagtc tcttctttgg
    23941 actttcacaa agtttggctg ttatcggttc tcaattgccg ttcctacaag gagtgccagc
    24001 ggtttatctt caaattgcac cttatgtttt gacaattctt gtcttagcag ccttctttgg
    24061 aaaagcagtc gcaccaaaag cagatggtat caactacatc aaatcaaaat aagcatacaa
    24121 aaaaacgtca gtccaatgac tgaactgccc cccaaaagtt agacagaaaa aatctaactt
    24181 ttggggtg
//
LOCUS       DAVBDR010000028        23023 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.028, whole genome shotgun sequence.
ACCESSION   DAVBDR010000028 DAVBDR010000000
VERSION     DAVBDR010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 23023)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23023)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23023
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.028"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            complement(<1..337)
                     /locus_tag="VQ540_001166"
     CDS             complement(<1..337)
                     /locus_tag="VQ540_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002202361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2544979.1"
                     /translation="MDSASIIAHTIHQKFNLKVPNYRQEEDWARMGLPITRKEIANWH
                     IKASQYYLESLYNLLREKLLEQPLLHADETSYRVLESDSQLTYYWTFLSGKSEKQGIT
                     LYHHDQCRSG"
     gene            complement(345..650)
                     /locus_tag="VQ540_001167"
     CDS             complement(345..650)
                     /locus_tag="VQ540_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase zinc-finger binding
                     domain-containing protein"
                     /protein_id="HET2544980.1"
                     /translation="MFPVETEEITYKRKKSKGKRQALLAQFDSEEVHHQVEESICSDC
                     QGDLKEIGATLQRQELVFIPAQLKRIDHIQHAYKCQACSDKNPSDKIVKAPIPKAPL"
     gene            complement(637..831)
                     /locus_tag="VQ540_001168"
     CDS             complement(637..831)
                     /locus_tag="VQ540_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2544981.1"
                     /translation="MKIIQQQSATIDSLTNALALLREQVAYLTQKLYGKSSEKSVCPS
                     GQLNLFEEESPSEKDGDVPS"
     gene            complement(907..1247)
                     /gene="tnpB"
                     /locus_tag="VQ540_001169"
                     /pseudo
     CDS             complement(907..1247)
                     /gene="tnpB"
                     /locus_tag="VQ540_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
     gene            complement(1228..1413)
                     /locus_tag="VQ540_001170"
     CDS             complement(1228..1413)
                     /locus_tag="VQ540_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001136123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2544982.1"
                     /translation="MPQPIVPVEIPQSRPFDSKKRNDILLKIRIGKLEVSFFQSLNLE
                     MVEQLLDKVLLYDNSSI"
     gene            complement(1717..3279)
                     /gene="guaA"
                     /locus_tag="VQ540_001171"
     CDS             complement(1717..3279)
                     /gene="guaA"
                     /locus_tag="VQ540_001171"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HET2544983.1"
                     /translation="MSNISTDLQDVEKIIVLDYGSQYNQLISRRIREIGVFSELKSHK
                     ISAAEVREVNPVGIILSGGPNSVYEDGSFDIDPEIFELGIPILGICYGMQLLTHKLGG
                     KVVPAGDAGNREYGQSTLTHTPSALFESTPDEQTVLMSHGDAVTEIPADFVRTGTSAD
                     CPYAAIENPDKHIYGIQFHPEVRHSVYGNDILRNFALNICKAKGDWSMDNFIDMQIKK
                     IRETVGDKRVLLGLSGGVDSSVVGVLLQKAIGDQLICIFVDHGLLRKGEADQVMDMLG
                     GKFGLNIVKADAAKRFLDKLAGVSDPEQKRKIIGNEFVYVFDDEASKLKDVKFLAQGT
                     LYTDVIESGTDTAQTIKSHHNVGGLPEDMQFELIEPLNTLYKDEVRALGTELGMPDHI
                     VWRQPFPGPGLAIRVMGEITEEKLETVRESDAILREEIAKAGLDRDIWQYFTVNTGVR
                     SVGVMGDGRTYDYTIAIRAITSIDGMTADFAKIPWEVLQKISVRIVNEVDHVNRIVYD
                     ITSKPPATVEWE"
     gene            3421..4119
                     /locus_tag="VQ540_001172"
     CDS             3421..4119
                     /locus_tag="VQ540_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000936186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HET2544984.1"
                     /translation="MLPAYMKIHDQIKKDIDEHRWAIGERLPSERDLAEQFAVSRMTL
                     RQAVSLLVEEGVLERRVGSGTFVSSTRVQEKMRGTTSFTEIVKSQGKVPSSQLISYKK
                     TIPNEQEVAKLGIFPTDNIIRMERVRYADQVPLVYEVASIPEKFIKDFKKEEITSHFF
                     QTLQKHGYRIGKSQQTIYARLAKEKIAHYLEVEKGHAILGLTQVSYLEDGTAFEYVKS
                     QYVGERFEFYLENN"
     gene            complement(4162..5058)
                     /locus_tag="VQ540_001173"
     CDS             complement(4162..5058)
                     /locus_tag="VQ540_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HET2544985.1"
                     /translation="MSNSLKGTLLTVVAGIAWGLSGTSGQYLMAHGISALVLTNLRLL
                     IAGGILMLLAYATAKDKILVFLKDRKSLLSLLIFALIGLFLNQFAYLSAIQETNAGTA
                     TVLQYVCPVGILIYSCIKDRVAPTLGEIVSIIFAIGGTFLIATHGQLDQLSMTPAGLF
                     WGLFSALTYALYIILPIALIKKWGSSLLIGVGMVIAGLVALPFTGVLQADIPTSLDFL
                     LAFAGIILIGTVFAYTAFLKGASLIGPVKSSLLASIEPISAIFFAFLIMNEQFYPIDF
                     LGMAMILFAVTLISLKDLFLEK"
     gene            complement(5067..6002)
                     /locus_tag="VQ540_001174"
     CDS             complement(5067..6002)
                     /locus_tag="VQ540_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HET2544986.1"
                     /translation="MKWTKIIKKIEEQIEAGIYPGASFAYFKDNQWTEFYLGQSDPEH
                     GLQTEAGLVYDLASVSKVVGVGTVCTFLWEIGQLDIDRLVIDFLPESDYPDITIRQLL
                     THATDLDPFIPNRDLLTAPELKEAMFHLNRRSQPAFLYSDVHFLLLGFILERIFNQDL
                     DVILKDQVWKPWGMTETKFGPVELAVPTVRGVEAGIVHDPKARLLGRHAGSAGLFSTI
                     KDLQIFLEHYLADDFARDLNQNFSPLDDKERSLAWNLEGDWLDHTGYTGTFIMWNRQK
                     QEATIFLSNRTYEKDERAQWILDRNQVMNLIRKEE"
     gene            complement(5999..6724)
                     /locus_tag="VQ540_001175"
     CDS             complement(5999..6724)
                     /locus_tag="VQ540_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001102210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CppA family protein"
                     /protein_id="HET2544987.1"
                     /translation="MNVNQIVRIIPTLKANNRKLNETFYIETLGMKALLEESAFLSLG
                     DQTGLEKLVLEEAPSMRTRKVEGRKKLARLIVKVENPLEIEGILSKTDSIHRLYKGQN
                     GYAFEIFSPEDDLILIHAEDDRASLVEVGEKPEFQTDLASISLSKFEISMELHLPTDI
                     ESFLESSEIGASLDFIPAQGQDLTVDNTVTWDLSMLKFLVNELDIASLRQKFESTEYF
                     IPKSEKFFLGKDRNNVELWFEEV"
     gene            complement(6808..7443)
                     /locus_tag="VQ540_001176"
     CDS             complement(6808..7443)
                     /locus_tag="VQ540_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-alkyl-2-acetylglycerophosphocholine esterase"
                     /protein_id="HET2544988.1"
                     /translation="MAVQLLENWLLKEQEKIQTKYRHLNHISVVEPNILFIGDSIVEY
                     YPLQELFGTSKTIVNRGIRGYQTGLLLENLDAHLYGGAVDKIFLLIGTNDIGKDVPVN
                     EALNNLEAIIQSVARDYPLTEIKLLSILPVNEGEEYQQAVYIRSNEKIQNWNQAYQEL
                     ASAYMQVEFVPVFDCLTDQAGQLKKEYTTDGLHLSIAGYQALSKSLKDYLY"
     gene            complement(7445..8272)
                     /locus_tag="VQ540_001177"
     CDS             complement(7445..8272)
                     /locus_tag="VQ540_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HET2544989.1"
                     /translation="MMIKVIATDMDGTLLDARGQLDLPRLEKILDQLDQRGIRFVIAT
                     GNEIHRMRQLLSPLVDRVVLVVANGARIFENNELIQAQTWDDAIVNKALAHFKGRACQ
                     DQFVVTGMKGDFVKEGTIFTDLESFMTPEMIEKFYQRMQFVDELTSDLFGGVLKMSMV
                     VGEERLSSVLEEINALFDGRVRAVSSGYGCIDILQAGIHKAWGLEELLKRWDLKSQEI
                     MAFGDSENDVEMLEMAGIAYAMENADEKAKAVATALAPANSQGGVYQVLENWLEKGE"
     gene            complement(8294..8630)
                     /locus_tag="VQ540_001178"
                     /pseudo
     CDS             complement(8294..8630)
                     /locus_tag="VQ540_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398793.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="poly-gamma-glutamate biosynthesis protein"
     gene            complement(8631..9347)
                     /locus_tag="VQ540_001179"
     CDS             complement(8631..9347)
                     /locus_tag="VQ540_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CapA family protein"
                     /protein_id="HET2544990.1"
                     /translation="MAHGDLLYHDGLFFSAKKEDGTYDFHENFEYVTPWLKQADLAIG
                     DFEGTINKDHYLAGYLLFNAPVEVMDAIKEAGYHVLDLAHNHILDSQIEGVISMADII
                     EKAGITPIGVYTHEPRDQAPLVIKEVNAIKVALLAYSYGFNGIEQYIFQEDYNRYLSD
                     LNEDKIKAEVERAEKEADITIIMPQMGVEYRLEPTEEQKALYHKMIDWGADIIFGGHP
                     HVVEPSKTVEKDGDKKLIIY"
     gene            9870..10481
                     /locus_tag="VQ540_001180"
     CDS             9870..10481
                     /locus_tag="VQ540_001180"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HET2544991.1"
                     /translation="MSAIERITKAAHLIDMNDIIREGNPTLRAIAEEVTFPLSDQEII
                     LGEKMMQFLKHSQDPVMAEKMGLRGGVGLAAPQLDISKRIIAVLVPNIVEEGETPQEA
                     YDLEGIMYNPKIVSHSVQDAALGEGEGCLSVDRNVPGYVVRHARVTVDYFDKDGEKHR
                     IKLKGYNSIVVQHEIDHINGIMFYDRINEKDPFAVKDGLLILE"
     gene            10526..11254
                     /gene="rlmB"
                     /locus_tag="VQ540_001181"
     CDS             10526..11254
                     /gene="rlmB"
                     /locus_tag="VQ540_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HET2544992.1"
                     /translation="MKTNDIVYGVHAVTEALLANTGNKLYLQEDLRGKNVEKVKELAT
                     EKKVSISWTSKKSLSEMTEGAVHQGFVLRVSEFAYSELDYILAKTRQEENPLLLILDG
                     LTDPHNLGSILRTADATNVSGVIIPKHRAVGVTPVVAKTATGAIEHVPIARVTNLSQT
                     LDKLKDEGFWTFGTDMNGTPCHKWNTKGKIALIIGNEGKGISSNIKKQVDEMITIPMN
                     GHVQSLNASVAAAILMYEVFLNRL"
     gene            complement(11293..12204)
                     /gene="trxB"
                     /locus_tag="VQ540_001182"
     CDS             complement(11293..12204)
                     /gene="trxB"
                     /locus_tag="VQ540_001182"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HET2544993.1"
                     /translation="MYDTIIIGAGPAGMTAALYAARSNLKVALIEGGLPGGQMNNTSD
                     IENYPGYANISGPELAEKMFEPLENLGVEHIYGYVENVEDHGDFKKVMTDDQTYETRT
                     VIVATGSKHRPLGVPGEEELNSRGVSYCAVCDGAFFRDQDLLVVGGGDSAVEEALFLT
                     RFAKTVTIVHRRDQLRAQKVLQDRAFANEKISFIWDSVVKEIKGENRVESVVFENVKT
                     GQVTEQAFGGVFIYVGLDPLSDFVKELNIQDQAGWIVTDSHMKTAVDGIFAVGDVRLK
                     DLRQVTTAVGDGAIAGQEAYKFITEHS"
     gene            complement(12270..12494)
                     /locus_tag="VQ540_001183"
     CDS             complement(12270..12494)
                     /locus_tag="VQ540_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4059 family protein"
                     /protein_id="HET2544994.1"
                     /translation="MLLQLFSLYFESLILTTILVLIFLGIWIGLRAMSGVDKTARARQ
                     AHLYDMIMIGVLVVPVLSFAVMSLILVFKA"
     gene            complement(12572..13315)
                     /locus_tag="VQ540_001184"
     CDS             complement(12572..13315)
                     /locus_tag="VQ540_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HET2544995.1"
                     /translation="MIKISNLSKSFSGQTVLDHLNLDIQKGEVVALIGSSGAGKSTFL
                     RSLNYLETPDSGSIQIDGFSVDFSKITQEEILALRRKLSMVFQQFNLFERRTALDNVK
                     EGLVVVKKLSDQEATKIAKEELAKVGLSDRENHYPRHLSGGQKQRVALARALAMKPDV
                     LLLDEPTSALDPELVGEVEKSIADAAKSGQTMILVSHDMSFVAQVADKILLLDKGKII
                     ESGTPDEIIHTPKEERTKEFFASYKRTYI"
     gene            complement(13315..14115)
                     /locus_tag="VQ540_001185"
     CDS             complement(13315..14115)
                     /locus_tag="VQ540_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001103446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET2544996.1"
                     /translation="MNVTTILASDWYQNLMQLIPDGKLFSLRSVFDGIPRIVQQLPTT
                     IMLTIGGALFGLVLALLFAIVKINRVKILYPLQAFFVSFLKGTPILVQLMLTYYGIPL
                     ALKALNQQWGTGLNINAIPAAAFAIVAFAFNEAAYASETIRAAILSVNPGEIEAARSL
                     GMTRAQVYRRVIIPNAAVVATPTLINSLIGLTKGTSLAFSAGVVEVFAQAQILGGADY
                     RYFERFISVALVYWVVNIGIESLGRFIERKMAISAPDTVQTDVKGDLR"
     gene            complement(14273..14629)
                     /locus_tag="VQ540_001186"
     CDS             complement(14273..14629)
                     /locus_tag="VQ540_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HET2544997.1"
                     /translation="MLEFIEYPKCSTCKKAKQELNQLGVDYKAVHIVEETPSQEVILN
                     WLETSGFELKQFFNTSGIKYRELGLKDKVGSLSNQEAAELLASDGMLLKRPILVENGT
                     VKQIGYRKSYEELGLK"
     gene            complement(14642..15154)
                     /locus_tag="VQ540_001187"
     CDS             complement(14642..15154)
                     /locus_tag="VQ540_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001170346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HET2544998.1"
                     /translation="MQKKYVKILYSSPIGILSLVADDHYLYGIWVQEQKHFERGLGDE
                     TIEEVVSHPILDPVIACLDDYFKGKPQDLSNLLLAPIGTNFEKRVWDYLQGIPYGQTV
                     TYGQIAQDLQVASAQAIGGAVGRNPWSILVPCHRVLGAGKRLTGYAAGVEKKAWLLEH
                     EGVDFKDINK"
     gene            complement(15154..15648)
                     /locus_tag="VQ540_001188"
     CDS             complement(15154..15648)
                     /locus_tag="VQ540_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2544999.1"
                     /translation="MEIRLAFPNEVDAIMQVMEDAKKCLADAGSDQWQNGYPNADVII
                     DDIISGQAYVALEEGELLAYAAVTKSPEEAYEAIYEGNWQAGESEYLVFHRIAVAADV
                     QGKGVAQTFLEGLIEGFDYLDFRSDTHAENKVMQHIFEKLGFKQVGKVPVDGERLAYQ
                     KLKK"
     gene            15783..16229
                     /locus_tag="VQ540_001189"
     CDS             15783..16229
                     /locus_tag="VQ540_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HET2545000.1"
                     /translation="MKTTFSYPKWAEIPNIDLYLDQVLLYVNQVCAPISPNKDKGLTA
                     SMVNNYVKNGYLTKPDKKKYQRQQIARLIAITTLKSVFSIQEIAQTLNTLQTQASSDQ
                     LYDAFVDYMNQGIDPANPIIQTSCQTVKLYHQTLDLIDHTQEEVIQ"
     gene            16226..16873
                     /locus_tag="VQ540_001190"
     CDS             16226..16873
                     /locus_tag="VQ540_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001097995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HET2545001.1"
                     /translation="MNTSLKLSKQLSFGEEIANSVTHAVGAVIMLILLPISSIYSYEA
                     HGFLSSIGVSIFVISLFLMFLSSTIYHSMAYGSTHKYVLRIIDHSMIYVAIAGSYTPV
                     VLTLMNNWFGYLIIVIQWGTTIFGILYKIFAKKVNEKFSLALYLIMGWLVLAIIPAII
                     SQTTPVFWSLMVTGGLCYTVGAGFYAKKKPYFHMIWHLFILAASALQYIAIVYYM"
     gene            complement(16894..17475)
                     /gene="pdxT"
                     /locus_tag="VQ540_001191"
     CDS             complement(16894..17475)
                     /gene="pdxT"
                     /locus_tag="VQ540_001191"
                     /EC_number="3.5.1.2"
                     /EC_number="4.3.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase glutaminase
                     subunit PdxT"
                     /protein_id="HET2545002.1"
                     /translation="MKIGILALQGAFAEHAKVLDQLGVESVELRNLDDFQQDQSDLSG
                     LILPGGESTTMGKLLRDQNMLLPIREAILSGLPVFGTCAGLILLAKEITSQKESHLGT
                     MDMVVERNAYGRQLGSFYTEAECKGVGKIPMTFIRGPIISSVGEGVEILATVNNQIVA
                     AQEKNMLVSSFHPELTDDVRLHQYFINMCKEKS"
     gene            complement(17476..18351)
                     /gene="pdxS"
                     /locus_tag="VQ540_001192"
     CDS             complement(17476..18351)
                     /gene="pdxS"
                     /locus_tag="VQ540_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012054698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase lyase subunit
                     PdxS"
                     /protein_id="HET2545003.1"
                     /translation="MTENRYELNKNLAQMLKGGVIMDVQNPEQARIAEAAGAAAVMAL
                     ERIPADIRAAGGVSRMSDPKMIKEIQEAVSIPVMAKVRIGHFVEAQILEAIEIDYIDE
                     SEVLSPADDRFHVDKKEFQVPFVCGAKDLGEALRRIAEGASMIRTKGEPGTGDIVQAV
                     RHMRMMNQEIRRIQNLREDELYVAAKDLQVPVELVQYVHEHGKLPVVNFAAGGVATPA
                     DAALMMQLGAEGVFVGSGIFKSGDPVKRASAIVKAVTNFRNPQILAQISEDLGEAMVG
                     INENEIQILMAERGK"
     gene            complement(18503..19882)
                     /locus_tag="VQ540_001193"
     CDS             complement(18503..19882)
                     /locus_tag="VQ540_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HET2545004.1"
                     /translation="MSKIVVVGANHAGTACINTMLDNFGNENEIVVFDQNSNISFLGC
                     GMALWIGEQIDGAEGLFYSDKDKLEAKGAKVYMNSPVLSIDYDNKVVTAEVEGKEHKE
                     SYEKLIFATGSTPILPPIEGVEIVKGNREFKATLENVQFVKLYQNAEEVINKLSDKSQ
                     HLDRIAVVGGGYIGVELAEAFERLGKEVVLVDIVDTVLNGYYDKDFTQMMAKNLEDHN
                     IRLALGQTVKAIEGDGKVERLITDKESFDVDMVILAVGFRPNTALADGKIELFRNGAF
                     LVDKKQETSIPGVYAVGDCATVYDNARKDTSYIALASNAVRTGIVGAYNACGHELEGI
                     GVQGSNGISIYGLHMVSTGLTLEKAKAAGYNATETGFNDLQKPEFMKHDNHEVAIKIV
                     FDKDSREILGAQMVSHDIAISMGIHMFSLAIQEHVTIDKLALTDLFFLPHFNKPYNYI
                     TMAALTAEK"
     gene            20177..21100
                     /locus_tag="VQ540_001194"
     CDS             20177..21100
                     /locus_tag="VQ540_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HET2545005.1"
                     /translation="MTLRSHSERLMGTTITISLVDEQADIFLQKSFDLLKELEYRFNA
                     NSQESELMEINYQAGISPVTVHPDLFELISLGLEHSLALSSHLNISIGPLIQTWRIGF
                     SDAKVAQPQEIESVLPLINPHGIELDSSTSTVFLKQKGMKIDLGCLAKGYSADKVAQF
                     LRKEGVTSALINLGGNILTIGKNQARGDNPWQIGIQDPANPRGNHLMTIPVVNKSVVT
                     SGIYERHLTVDGQDYHHIFDSQTGYPVETELASLTIISDKSVDGEIWTTRLFGERPAS
                     ILWQVESLEGIEVILIDKEGHLSCSSGIPTL"
     gene            21160..21765
                     /locus_tag="VQ540_001195"
     CDS             21160..21765
                     /locus_tag="VQ540_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HET2545006.1"
                     /translation="MLKLIAIVGTNSKRSTNRQLLQYMQKHFADKAEIELVEIKTIPV
                     FNKPADKQVPAEILEIAAKIEEADGVIIGTPEYDHSIPAVLMSALAWLSYGIYPLLNK
                     PIMITGASYGTLGSSRAQLQLRQILNAPEIKANVLPDEFLLTHSLQAFNPSGDLVDLD
                     VIKKLDAIFDDFRIFVKITEKLRNAQELLRKDAEDFDWENL"
     gene            21783..>23023
                     /locus_tag="VQ540_001196"
     CDS             21783..>23023
                     /locus_tag="VQ540_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000673688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HET2545007.1"
                     /translation="MKFVGLVGSNYDQSYNRKLLEFIRRNFKFKFELEVLEIDEVPMF
                     NQDEKWDESFQLRFLYNKITRADGVIIATPEHNHTISASLKSVLEWLSYEVHPFENKP
                     VMIVGASYYDQGTSRAQVHLRKILDAPGVNAYTLPGNEFLLGKAKEAFDNNGNITNEG
                     TVKFLETCLDNFVKYVGVVSKLKKPKPIESEDLDCGKPIATTITEVDPDDPEWVEKVA
                     AITGAVSGDTYVKLDHGILTVNQIDMFLKAMPFELTYADDNNQFLYYNNAHQDPDTMF
                     AKRVPPQSGSRMSTVHGSLPPARMKNVEWVIGTLRNGNQEYVRTIVPGSPAGVINTHN
                     YQAMYYPDGSYAGINEIVFNFQPWLDWYLKETGQRLVGGSGPFAPAAGGHGDADATSG
                     ASDSGDAGGHGGDADATAGAS"
BASE COUNT         6846 a         5158 c         4197 g         6822 t
ORIGIN      
        1 aaccacttcg acactgatca tggtggtaaa gcgtaatccc ttgtttctct gatttacctg
       61 acaaaaaagt ccaatagtaa gtcagctgac tatcactttc taagacccga taagaggttt
      121 catctgcatg aagaagaggt tgttctaaca acttttctcg taaaaggtta taaagggact
      181 ctaaatagta ttgactcgcc ttgatatgcc aattagcaat ttccttacgt gtgattggta
      241 aacccatcct agcccaatct tcttcttggc gataattagg taccttcaga ttaaacttct
      301 gatggatggt gtgagcgata atagaagctg agtcaatagt ctcgttataa aggggcttta
      361 ggaataggag ctttcacaat tttatcactc ggatttttat cactgcatgc ttggcatttg
      421 taagcgtgtt ggatatgatc tatgcgtttt aattgcgcag gaataaagac taattcttgt
      481 cgttgaaggg ttgctccaat ctcttttaga tctccctgac aatcagagca aatgctctct
      541 tctacttgat gatgaacttc ttctgaatca aattgggcaa gaagagcttg gcgtttccct
      601 ttagatttct tacgtttgta ggtaatttcc tctgtttcaa ctgggaacat ctccatcttt
      661 ctcagatgga gactcttcct caaaaaggtt gagttgtcca gaggggcaaa cacttttctc
      721 agaggatttt ccatagagct tttgagtcag ataagccact tgttcacgaa gaagggcaag
      781 tgcattggtg agactatcaa ttgtagcact ctgttgttga atgattttca atcttcttcc
      841 atgggcttcc cctccttgtt ttctaccttt attatactaa aaagaaagtc ctcatttcaa
      901 tagaaatcac gactttctga tggatttatt tttggagtga tagaaaagtc cttcataagc
      961 cagtctactt gttcagatgt gagagctttg acatcctttt ctgtactggg ccaagtcagt
     1021 ctgccgttcc caaagcgttt atatagtagc caaaatcctt gaccatccca gtaaagggct
     1081 ttaaagcggt atttacgtcc accacaaaag agaaaaactt gacctgagaa aggatctaat
     1141 tcaaagtggg ttttaaccag ataagccagt gaatcaatgc cttgcctcat atccgttttc
     1201 ccacatacga gatagacctg ccctaggcta gatagatgaa ttgtcataga gcaacacctt
     1261 atccaaaagc tgttctacca tttcgagatt gagagattga aaaaaactta cttcaagctt
     1321 gccaatacga attttaagca gaatatcatt tctcttttta gaatcaaaag gacgagattg
     1381 tggaatctct acaggaacaa taggttgtgg cattaaaata tcctccaata gttttacttt
     1441 actaatagta tacaggagga actccatgaa tgatagatac cttgttatga cgcgattact
     1501 atattagaaa gttggctctc taattaaatt aattctcatt atatatatca aaagaccgca
     1561 gcttgaaaac tacggtctaa ttttttgtcc aaatgtaaac cacttggaac tattattcaa
     1621 tttattcttt ttagtaaatg ttcccgtttt aatcccagtt acagttttta atcctctgta
     1681 accgttgatt ttacaaagct tttaattttt ttgcgattat tcccactcaa ctgttgcagg
     1741 tggtttactt gtaatatcgt agacgatacg gttaacatga tccacttcat ttacgatacg
     1801 tactgagatt ttttgaagta cttcccatgg aattttggca aaatcagcag tcataccatc
     1861 gatagaagtg atagcacgga ttgcaatcgt gtagtcatat gtacgaccgt cacccataac
     1921 accgactgaa cgaacgcctg tgttaacagt gaagtattgc caaatatcgc ggtcaagtcc
     1981 agctttagcg atttcttcac gaagaatagc gtctgattca cgaacggttt caagtttctc
     2041 ttcagtgatt tcacccatga cacggatagc aagtcctggt cctgggaatg gttggcgcca
     2101 tacgatatgg tctggcatac caagctctgt accaagagca cgaacttcat ccttgtaaag
     2161 agtattgagt ggttcaatca attcaaactg catatcttct ggaagaccac ccacgttgtg
     2221 gtgtgacttg atagtttgag ctgtatccgt accagactcg ataacatctg tatataaagt
     2281 accttgagca aggaatttca catctttgag cttgcttgct tcgtcatcga atacatagac
     2341 aaactcgtta ccgatgattt tacgtttttg ttcaggatca gaaacgccag caagtttgtc
     2401 aaggaaacgt ttagcagcgt ctgctttgac gatattcaaa ccaaacttac caccgagcat
     2461 gtccataact tgatcagctt cgcctttacg aagaagaccg tggtctacga agatacagat
     2521 caattgatcg ccaatcgctt tttggagaag aaccccaacg acagatgagt caacaccacc
     2581 tgatagacca agaaggacac gtttatcacc gacggtttca cgaatttttt tgatctgcat
     2641 gtcaatgaaa ttatccattg accagtcacc tttagcctta caaatgttaa gggcaaagtt
     2701 acgaaggata tcatttccgt atacagaatg acgaacttct gggtggaatt ggataccgta
     2761 aatgtgttta tctgggtttt cgatggctgc gtatgggcag tcagctgatg tacctgtacg
     2821 aacaaagtca gcaggaatct cagtaaccgc atcaccatgg ctcatcaaaa cagtctgttc
     2881 atcaggtgtt gattcaaaaa gcgctgatgg tgtgtgagtt agggttgatt gaccgtattc
     2941 acgatttcca gcatcacctg caggaacaac ttttcctcca agtttatggg tcaataactg
     3001 cataccataa cagattccca aaattggaat tccgagttcg aagatttctg ggtcaatatc
     3061 aaatgaacca tcttcatata cagaatttgg accacctgat agaataattc ctacaggatt
     3121 gacttcacga acttcagcag ctgaaatttt atggcttttt agttctgaaa aaacaccaat
     3181 ctcacggata cggcgtgaaa tcagctggtt gtactggcta ccatagtcca atacgatgat
     3241 tttttctaca tcttgcaaat cagttgaaat gttgctcatc tttttccttt ctcaaaagaa
     3301 atatcttttc tcaatattct atcacaaata agggcgaatt accaactaaa caaggcgaag
     3361 tttgactttt tctagtttat tggggtacaa tagagaaaag atagaaatga agtgaaaaat
     3421 atgctacctg cttatatgaa aatccatgat cagataaaaa aggatattga cgagcaccgt
     3481 tgggctattg gtgagaggct tcccagtgaa agagatttag ctgagcagtt tgcggtcagt
     3541 cgcatgaccc tccgccaagc cgtatctcta ttagtcgaag aaggcgtctt agagcgccgt
     3601 gtaggaagcg gcacctttgt ttccagtact cgagtacaag aaaagatgcg agggacaacc
     3661 agttttactg aaattgtcaa atcccaaggt aaagttccct ctagccagct catttcctac
     3721 aaaaaaacca ttcccaatga gcaagaagtt gccaagctag gaatttttcc aacggacaat
     3781 attatccgaa tggagcgggt ccgctatgcc gaccaagttc ccctagttta tgaagttgct
     3841 tctattcctg aaaaattcat taaggacttt aaaaaagaag aaatcacaag tcatttcttc
     3901 caaaccttgc aaaaacatgg ctatcgtatc ggcaaatctc aacagaccat ctatgctcgc
     3961 cttgctaaag aaaagattgc ccactatttg gaagttgaaa aaggacatgc tattcttgga
     4021 ttgacccagg tttcctacct agaagatggt actgcttttg aatacgtaaa aagtcaatat
     4081 gtaggcgaac gctttgaatt ttatcttgaa aataattaga ttaccacgca aaaactctct
     4141 gtcacggaca aagagtcttt tttatttttc taagaataaa tctttcaaag aaatcaaagt
     4201 tacagcaaac aatatcattg ccataccaag aaaatcaatg ggataaaatt gttcattcat
     4261 tattaagaag gcaaagaaaa tcgccgatat tggctcaatt gaagccaaca agcttgactt
     4321 gaccggtcct atcagactgg ctcctttaag gaaagctgta taggcaaaga cagtcccgat
     4381 aaggataatg cctgcaaacg caaggagaaa atcaagacta gtcgggatat cggcctgtag
     4441 aacccctgta aaaggaaggg cgaccaaacc tgctatgacc attcccacac caatgagcaa
     4501 gctgctcccc cactttttaa tcaaggctat gggtaaaatg atatacagag cataagtcaa
     4561 ggcagaaaag agaccccaga acagaccagc aggtgtcatg gataactggt ccaactgccc
     4621 atgtgttgcg atcaggaagg ttcctccgat ggcgaatatg atggaaacta tctctcccag
     4681 tgtcggtgcc accctatcct tgatacagct ataaattaaa attccgacag gacaaacata
     4741 ctgaagcacc gtcgctgttc ccgcattggt ctcctgaata gcagacagat aggcgaattg
     4801 gttgagaaaa agaccaatca gagcaaaaat aagaagagac agcaaactct ttctatcctt
     4861 taaaaagacc agtattttat cctttgcagt agcataagcc aagagcatga gaattccacc
     4921 agcgattaaa agacgcaagt tggtcaagac cagagccgaa attccgtgtg ccattaggta
     4981 ttggccactc gttcctgaca acccccaagc aataccagcc acaactgtta gtaaagtccc
     5041 ttttaaacta tttgacatgt ctctccttac tcttctttgc gaatcaagtt catcacttga
     5101 ttgcggtcta atatccattg agctctctcg tccttttcat aggtacgatt cgataggaaa
     5161 atagtggctt cttgcttctg acgattccac atgataaagg tacctgtata gcccgtatgg
     5221 tctagccaat ctccttccaa attccatgct aaagaacgtt ccttgtcatc caaaggagaa
     5281 aaattttgat ttaagtctct tgcaaaatca tctgctaaat agtgttctaa aaagatttgt
     5341 aaatccttta tagtcgaaaa taaaccagca ctcccagcat gtctacccag gagacgagcc
     5401 ttgggatcat gcactatgcc tgcctctaca cctctaactg ttggaacagc aagctcaact
     5461 ggcccaaact tggtttccgt cattccccaa ggtttccaga cttgatcctt taaaatcaca
     5521 tccaaatctt gattaaaaat tctttccaaa ataaagccca acagcaaaaa atggacatcc
     5581 gaataaagaa aggctggctg acttcgtctg ttgagatgaa acatcgcttc ctttaattca
     5641 ggggctgtta aaagatcacg attaggaata aaaggatcaa ggtctgttgc atgagtcaag
     5701 agctggcgaa tagtgatgtc tggataatca ctctcaggta aaaaatctat taccagtcta
     5761 tcaatatcta attgacctat ttcccacaag aaggtacaaa ctgtgccaac cccaacaacc
     5821 ttgctgacac tagctagatc ataaactagt cctgcctcag tctgcaagcc atgctctggg
     5881 tcactctggc ctaaatagaa ctctgtccat tgattgtcct taaaatacgc aaaagaggct
     5941 ccgggataaa ttcctgcctc gatttgttct tctatttttt taataatctt ggtccacttc
     6001 atacttcttc aaaccacaat tcaacattat ttctatcttt accaaggaag aatttttcag
     6061 acttaggaat aaaatattca gtagactcaa acttctggcg aagacttgct atgtctaatt
     6121 cattgaccaa gaacttgagc atagataagt cccaggtaac cgtattgtcc acagtcaaat
     6181 cctgcccctg agctggaata aaatcaaggg atgccccaat ttcagatgat tccaagaaac
     6241 tttcgatatc agttgggaga tgtaattcca tagaaatctc aaatttactt aaagaaattg
     6301 atgccaaatc tgtttgaaat tcaggctttt ctcctacttc tactagactt gctctgtcat
     6361 cttccgcatg aatcaaaatc aaatcatctt ctggtgagaa aatttcaaaa gcgtagccat
     6421 tttgaccttt atataatcga tgaatcgaat ctgttttaga taagattcct tcaatttcta
     6481 agggattttc caccttgaca atcaatctag ctagtttttt tcttccctct accttacgag
     6541 tacgcatact gggagcttct tctaaaacca gcttttcaag acccgtttgg tcacctagtg
     6601 acagaaaggc cgattcttct aacaaggcct tcattccaag ggtttcaata taaaatgttt
     6661 catttaattt tctattatta gcttttaaag taggaataat ccgtacaatc tgatttacat
     6721 tcataaattc ctccgtcact ttttatttta aaggatttta gaatttttta caagatatta
     6781 tgctcaaatt taacattatt tagctattta gtaaagatag tctttcaagg attttgacaa
     6841 agcctgataa ccagcaatac tgaggtgcag tccatcagtt gtatattctt ttttgagttg
     6901 gcctgcttgg tctgtcaaac aatcaaatac tggcacaaat tccacctgca tataggcaga
     6961 tgcaagctct tgataggctt gattccagtt ctgaattttt tcattcgagc ggatatagac
     7021 tgcctgctgg tactcctctc cctcattgac aggcaaaatg gaaagcaatt taatctctgt
     7081 caatggataa tcgcgagcaa cggattgaat gatagcttcg agattattga gagcctcatt
     7141 cacaggaaca tcctttccga tatcatttgt cccaatcaga agaaaaattt tatctactgc
     7201 tccaccatat agatgagcat caagattctc tagtaacagt cctgtctgat agccacgaat
     7261 tcctcgattg acaatcgtct ttgaagtccc aaatagctcc tgtagaggat aatactcgac
     7321 aatggaatcc ccaataaaaa gaatgtttgg ttctacaaca gaaatgtgat ttaggtgacg
     7381 atacttagtt tgaatttttt cttgttcctt taggagccaa ttttctaata actgtactgc
     7441 cacttcattc tcctttttct aaccagtttt ccaagacttg ataaactcct ccttggctgt
     7501 tggctggtgc tagagcagtc gccacagctt tggctttctc atcagcattt tccatcgcat
     7561 aggcaattcc agccatttca agcatttcaa catcattttc actatcacca aaagccatga
     7621 tttcttggga tttcaagtcc cagcgcttga gtaattcctc caagccccat gctttatgaa
     7681 tcccagcttg gaggatatca atgcaaccat agccactgga tacagctcgg acacggccat
     7741 caaagagagc attgatttct tccaaaaccg aactcaaacg ttcctcacca acaaccatgc
     7801 tcatcttgag cacaccacca aagaggtcag atgttaattc atccacaaat tgcatccgtt
     7861 ggtagaattt ttcaatcatt tctggagtca taaaactttc aagatctgta aaaatcgtac
     7921 cttccttgac aaaatcaccc ttcatccccg ttacaacaaa ctggtcctga cacgctcgac
     7981 ccttgaaatg agccaaagcc ttgttgacaa tggcgtcatc ccatgtctga gcctgaatca
     8041 attcattgtt ttcaaaaata cgagcgccat tagcaacaac cagaaccact cgatccacca
     8101 agggactcag tagttgtctc atgcggtgaa tttcattgcc cgtcgcaatg acaaaacgaa
     8161 tgcccctttg atccaactga tctaaaatct tttccaatcg tgggagatca agctgacccc
     8221 tagcatccag caaggtccca tccatatctg tcgcaattac cttaatcatc atttactttc
     8281 ctctggattc aagctaatac cacttcaatc ccacatgttc attcatttct ttataggctg
     8341 tatcaattcg ttccttagtc gcttcatcta actggtcacg atgactgcca cccctctata
     8401 aaatcttcca aaatataagt ttggtaatga tacaagggat atccttctgg tgaaaaggtt
     8461 ccctttggtg ttcgattgac ccaagtagga tgagctttag ctgttccgat agttgttttt
     8521 ccatccttct tcttgatggt gacatccatg agaacaccac gttcagtcca cttagcattc
     8581 tcttcatctc ccatagattc aatccgttga ttggaaatga agttccccat ttaatagata
     8641 atgagtttct tatctccatc tttttcaacc gttttagatg gttcaacaac gtgaggatgc
     8701 cctccaaaga taatatccgc tccccaatcg atcatcttgt gataaagagc tttttgttct
     8761 tcagttggtt ccaatcgata ctcaacaccc atctgaggca tgataatggt gatatctgct
     8821 tccttctctg cccgttcgac ttcagccttt atcttatctt cgtttaaatc tgaaagataa
     8881 cgattatagt cttcctgaaa aatatactgc tcaattccat tgaaaccata ggaataggct
     8941 aacaatgcaa ccttgatagc attcacttcc ttaatgacca gcggagcctg atcacgtggt
     9001 tcgtgcgtat aaactccgat tggagtgatt ccagctttct caataatatc ggccattgaa
     9061 ataactccct caatttgcga atccaaaata tgattatgag ctaaatccag cacatgataa
     9121 cctgcttcct taatagcatc cataacttca acaggagcat taaagagaag ataacccgct
     9181 aaataatgat ccttattaat ggttccttca aaatcaccaa tagctaaatc tgcttgcttg
     9241 agccaaggag tcacatactc aaaattttca tgaaagtcat aggtaccgtc ttctttttta
     9301 gctgaaaaga aaagtccatc gtggtagagc aaatccccgt gggccataat tctggcagtt
     9361 ttttcctctt cctactcctg agacttttgc ttagtcccct cttgagaaat agtatctcgt
     9421 ttttgactag tcaagggatt ccttggaagc tttcaaacaa caagaccaag cccattgata
     9481 aaccaactgc tagcaagagt atcgccacaa atcccttatt gctccacttg cgataactcc
     9541 taaaaagttt accaagccct tcataaaacg aaaagctaaa ccaccctgat ttcgattttg
     9601 tcttctttgt atcttcattc tccctacttt cttatgcaag ccttttcttt ttattatatc
     9661 acagataagt atttctttca caattgaatt gaacttccca tctattttct ataaatccta
     9721 aatgccataa tgctttcaat tcttgtcatt ttgtgatatc atgtagaggt aatgaaagga
     9781 aatgaactaa tccacagtgg cttattccaa gtataccact tgggctttgg cagtagttaa
     9841 ctgcactaaa cataatataa ggagagaaaa tgtctgcaat agaacgtatt acaaaagctg
     9901 ctcacttaat tgatatgaac gatattatcc gtgaagggaa tcctactcta cgcgcgattg
     9961 ctgaggaagt cactttcccc ctatctgacc aggaaatcat cctaggcgaa aagatgatgc
    10021 aattccttaa acattcccaa gatcctgtca tggctgaaaa aatgggactc cgcggtggtg
    10081 ttggactggc tgctccccag ttagatatct caaaacgcat tatcgctgtt ttggtaccta
    10141 atattgttga agaaggcgaa actccacagg aagcctacga tttggaaggc attatgtaca
    10201 atccaaaaat cgtctctcac tctgttcaag atgctgctct tggcgaagga gaaggttgcc
    10261 tgtctgttga ccgtaacgtg cctggctatg ttgttcgcca tgcccgcgtt actgttgact
    10321 actttgacaa agatggagaa aaacaccgta tcaaactcaa aggctacaac tccattgttg
    10381 ttcagcatga aattgaccac attaacggta tcatgtttta cgatcgcatc aatgaaaaag
    10441 acccatttgc agttaaagat ggtttactga ttcttgaata aagaaaatcc cgttgcaaga
    10501 cggggttttg tgttataata gaggcatgaa aacaaatgat attgtctatg gtgtccacgc
    10561 cgttaccgaa gccctccttg caaatacagg aaacaaactc tacctccaag aagatctccg
    10621 aggtaagaat gttgagaaag tcaaggaact agctacagaa aagaaggtgt ccatttcttg
    10681 gacatcaaaa aaatctctct ctgagatgac tgaaggtgct gttcatcaag gttttgttct
    10741 acgagtgtct gaatttgcct atagcgagct agattacatc cttgcaaaaa cacgccaaga
    10801 agaaaatcca cttctattga ttctagatgg tctaaccgat ccccataatc tgggttctat
    10861 cttgcgaaca gccgatgcga ccaatgtttc aggtgtcatc attcccaagc accgtgctgt
    10921 cggagtaact cctgtcgttg ccaaaacagc cacaggtgct attgaacacg ttccaattgc
    10981 ccgagtgaca aacctcagtc aaaccttaga taaactcaag gatgaaggct tctggacctt
    11041 tggaacggat atgaacggta ctccttgcca caagtggaat acaaaaggga aaatcgccct
    11101 catcatcgga aatgaaggaa aaggcatctc tagcaacatc aaaaaacagg tcgatgaaat
    11161 gattaccatt ccgatgaatg gacatgttca aagcctcaat gccagtgttg ctgcagccat
    11221 tctcatgtac gaagtttttc taaatagact ataaaaaagt ttccagtcat ctgattggaa
    11281 acttttttat gattaactat gttctgtgat aaacttgtag gcttcttgac cagcgatagc
    11341 tccatctcca actgctgttg ttacttggcg aaggtctttc aagcgaacat ctccaactgc
    11401 aaagataccg tcgactgcag tcttcatgtg gctatctgtc acaatccagc ctgcctgatc
    11461 ttggatattc aattctttaa caaaatcgct aagagggtcc aaaccaacat agataaagac
    11521 accaccgaag gcttgctctg tcacttgacc tgttttcaca ttttcaaaaa cgacagattc
    11581 tactctgttt tcacccttga tttccttcac tacagaatcc cagataaagc tgattttttc
    11641 attcgcaaag gcgcgatctt gtaaaacctt ttgggcacga agttggtcac gacggtgaac
    11701 aatggtaaca gtcttagcaa aacgagtcaa gaagagggct tcttcaacag ctgaatctcc
    11761 accaccaact accaataaat cttggtcacg gaagaaagca ccatcacaca cagcacagta
    11821 agaaacacca cgactgttca gttcttcttc tccaggcact cccaaaggac ggtgtttaga
    11881 accagttgct acgataactg tacgtgtttc atatgtttgg tcatcagtca tcactttctt
    11941 aaaatcacca tggtcttcga cattttcaac ataaccataa atgtgctcaa caccaagatt
    12001 ttcaagtggt tcaaacatct tttcagccaa ttcaggtcca ctaatattag cgtatcctgg
    12061 gtaattttcg atatcagatg tattattcat ctgaccacct ggcagaccac cttcaatcaa
    12121 agctactttt agattgcttc gagcagcata caaggccgca gtcatccctg caggtccagc
    12181 accgataata atagtatcgt acatatagat tccttctttc ttgttgtaac tatctttatt
    12241 ctaactcttt cttgtcaatc acgcaaggat tatgccttga aaacaagaat taaactcata
    12301 accgcaaagg ataatactgg gacaaccaag actccaatca taatcatatc atagagatgg
    12361 gcttggcgag ccctggctgt cttatcaact cccgacatgg ctctcagacc aatccaaatc
    12421 cctaaaaaaa tcagaacaag gatggtggtc aagatcaaac tctcgaaata taaagaaaat
    12481 agttgcagta gcatgatttc tctcatttct atctttttta aagagtaaac tcagctagtc
    12541 caactaactg agttttcctt tatctattat atcaaatata agtccgtttg taactagcga
    12601 agaattcttt tgtccgctct tctttagggg tgtggataat ctcatccgga gttccagact
    12661 cgatgatttt ccccttatct aataagagaa ttttatccgc aacttgggct acaaaggaca
    12721 tgtcatgact gaccaaaatc atggtctgac ctgacttagc agcatctgca atagactttt
    12781 ctacttcacc gaccaattct gggtcaaggg ctgaagttgg ttcgtctaag agcaaaacat
    12841 ctggtttcat agcaagcgca cgcgctaggg caacccgttg cttctgtcca cctgataaat
    12901 ggcgaggata atggttttca cggtccgaaa gcccaacctt agccaactct tccttggcaa
    12961 tcttagtcgc ttcttggtca gataatttct tgacaacaac caagccttct ttcacattat
    13021 caagtgctgt tcgacgttca aataaattaa actgttggaa aaccatagac aacttacggc
    13081 gtagggcaag gatttcttct tgagtgattt tagaaaaatc aactgaaaaa ccatcaatct
    13141 gaatagagcc actgtcaggt gtttcaagat aattgagact gcgaagaaag gttgattttc
    13201 cagctcctga agaaccaatc aaggctacaa cttccccttt ttgaatatcc aagttcagat
    13261 gatccaagac agtctgtcct gaaaaggatt tgcttaaatt cgaaatctta atcattaacg
    13321 aaggtctcct ttcacatctg tttgcactgt atcaggtgca gaaatagcca tttttctctc
    13381 gatgaaacga ccgaggcttt caattccgat attgactacc caataaacaa gggcaacaga
    13441 gatgaagcgt tcaaaatagc gataatcagc tccacctaga atctgagctt gggcaaagac
    13501 ttccacaaca cccgcactaa aagctagaga tgttcccttg gtcaaaccga tgagggaatt
    13561 aatcaaggtt ggagtagcta ccaccgctgc attaggaata atcactcgtc gataaacttg
    13621 cgctcgggtc atacccagac tgcgcgccgc ctcaatctca ccaggattaa ctgagagaat
    13681 ggctgcacga atggtttcac tagcataagc tgcctcatta aaggcaaaag cgacaatcgc
    13741 aaaagctgca gctggaatcg cattgatatt gagaccagtt ccccattgct gattgagggc
    13801 tttcaaagcc aaagggattc cgtagtaggt caacatgagt tgcaccaaaa tcggtgtccc
    13861 ttttaagaaa ctaacaaaga aggcctgcaa gggatataaa atcttgacac gattgatctt
    13921 cacaatggca aaaagaagcg ccaaaaccaa gccaaaaagg gcaccaccaa ttgtcaacat
    13981 aattgttgtt ggaagttgtt ggacaattct agggattcca tcaaagaccg aacgtaggct
    14041 aaacagcttg ccatccggaa tcaattgcat caagttttgg taccaatctg atgctaaaat
    14101 cgttgtaaca ttcataaaaa catcctcttc tgataatgat tcattctacc atgcttctgc
    14161 cgtcaatgaa attatttgct acggtcagat acagactttg tctacctact agtttatcat
    14221 actttgaaac agggaagtta tatattttat ctatcaaaga gatagataaa aactatttca
    14281 gtcccagttc ttcataagat tttcgataac cgatttgctt aacagttcca ttttctacta
    14341 aaatgggccg ttttaacaac ataccgtcac ttgctagcaa ctcagccgct tcttggtttg
    14401 acaaacttcc taccttatct tttagcccta attcacggta tttgatacca ctggtgttga
    14461 aaaattgctt caattcaaat cctgaggttt ctagccaatt caaaatgact tcttggctag
    14521 gtgtttcttc cacgatatgg acggctttat agtccacacc taattgattt aattcttgtt
    14581 ttgctttttt acaagttgaa catttggggt attcgataaa ttctaacatg tgcttctcct
    14641 tctatttgtt tatatcttta aaatctacgc cttcatgctc caagagccaa gctttctttt
    14701 ccactcctgc agcatagcct gtcagacgct tgcctgctcc caacacacga tgacaaggta
    14761 ctaggataga ccaaggattg cgtcccactg ctccaccaat tgcttgagca gaagccactt
    14821 gcaggtcttg agcaatttgt ccataggtca ctgtctgacc ataaggaatg ccctgtaaat
    14881 agtcccaaac tctcttttca aaattcgttc cgattggcgc caagagcaag ttggataaat
    14941 cctgaggctt gcctttaaag taatcatcta agcaagcaat aactgggtct aaaataggat
    15001 gactaacaac ttcttctatc gtttcatctc ctagtcccct ctcaaaatgc ttctgctcct
    15061 gaacccaaat tccatacaaa taatggtcat cagctacaag tgatagaata ccaattggtg
    15121 aggagtagag tatttttaca tacttctttt gcattatttc tttaattttt gataggccaa
    15181 gcgttcgcca tctactggca ccttaccaac ttgtttaaaa ccaagttttt caaaaatatg
    15241 ttgcataacc ttgttttcag catgcgtatc tgagcgaaaa tcaagataat caaaaccttc
    15301 aatcaagccc tctaagaagg tttgagcaac tccttttccc tgcacatctg ctgccacagc
    15361 aatacggtga aagactagat actctgactc tccagcttgc cagtttccct cataaatagc
    15421 ttcataggcc tcctctggac tcttggtcac agcagcatag gctagcagtt ctccctcttc
    15481 caaggctacg taggcttgcc ctgagatgat atcatcgata ataacatctg catttggata
    15541 gccattttgc cactggtcac taccagcatc tgctaaacat tttttggcat cctccatcac
    15601 ctgcatgatg gcatctactt catttggaaa agctaaacga atttccatct tttttcctca
    15661 tttctgacta gtttctccca tcatagcata atttaagtat ttctacaagc agttaaaact
    15721 tgactttgtg tttttgttat tttataatct agttatcaaa actatataaa aaggagttga
    15781 aaatgaaaac taccttttcc tacccaaaat gggcagaaat tccaaacatt gacctctatc
    15841 tggaccaggt tttgctctat gtcaatcagg tctgcgcccc tatctctcct aataaagaca
    15901 agggcctaac agcatctatg gtcaacaatt atgtgaaaaa tggttacctg acaaagcctg
    15961 acaaaaaaaa ataccaacgc caacagattg cccgtttgat tgctatcaca accctcaagt
    16021 ctgtattttc tattcaagaa atagcccaga cacttaatac tctacaaact caagcaagtt
    16081 cagaccaact ctacgatgct tttgtggact acatgaacca aggaattgac ccagctaacc
    16141 ctattatcca aaccagctgc caaaccgtca aactctatca tcaaactcta gacttaatcg
    16201 atcatactca agaggaggta atccaatgaa cactagtctt aaactcagca aacaactcag
    16261 ttttggagag gagattgcta atagcgtgac ccatgctgtg ggtgcagtca tcatgcttat
    16321 cttgctgcct atttcatcca tctatagtta tgaagcacac ggatttttat cctctatcgg
    16381 cgtttccatt ttcgtcatca gtctctttct catgttccta tcatccacca tttatcactc
    16441 tatggcctat ggttcgaccc acaaatatgt tttgcgaatc attgaccatt ctatgattta
    16501 cgttgccatt gccggctcat acacgcccgt tgtcttgacc ttgatgaata actggtttgg
    16561 ctatctgatt attgtcatcc aatggggaac gaccatcttt ggtattctct ataaaatctt
    16621 tgctaaaaag gtcaatgaga aatttagcct tgctctttac ctgattatgg gctggttggt
    16681 tctggctatc attcctgcca ttatcagtca aacgacaccc gttttctgga gtctcatggt
    16741 aactggcgga ctctgttata cagttggagc tggattttat gccaagaaaa aaccttattt
    16801 ccacatgatt tggcatctct ttatcctagc tgcgtccgca cttcaataca tcgctattgt
    16861 ttattacatg taaaaaagtt gagaaattca atctcaactt ttttctttac acatattgat
    16921 aaagtactgg tgcaagcgca catcatcagt caattctgga tgaaaagaac ttaccaacat
    16981 atttttttct tgggctgcaa caatttgatt gttcactgtt gctagaattt ctacaccctc
    17041 accaacacta ctgataatcg gaccacggat aaaggtcatt ggaatcttgc caactccctt
    17101 acattctgct tccgtgtaga aacttcctaa ttggcgccca taagcattac gctcgaccac
    17161 catatccata gttcctagat gactctcttt ctgagaagtg atttccttag ccagcaaaat
    17221 taagcccgca caggtcccaa acactggtaa gccagataga atggcttctc ggatgggaag
    17281 tagcatgttc tggtcacgta agagcttgcc catggttgta gactcaccac caggcaaaat
    17341 caaacccgac aagtcactct gatcttgctg aaaatcatct agatttctga gttctacact
    17401 ctcgacacct aattgatcta gcacttttgc atgttctgca aaggcccctt gcaaggccaa
    17461 tattccaatt ttcatctatt ttcctcgttc agccatgaga atttggattt cattttcatt
    17521 aataccaacc atggcttctc ctaaatcttc agagatttga gctaggattt gaggattacg
    17581 gaagttagtc acagccttaa caatggcact cgctcgttta acaggatctc ctgacttgaa
    17641 aatacctgaa ccgacaaaga ccccctctgc ccctaattgc atcattaacg cagcatctgc
    17701 tggcgttgca acacctccag cagcgaaatt tacaactggc aattttccat gttcatgaac
    17761 atattggacc aattctacag ggacttgcaa atccttggca gcaacataaa gctcgtcctc
    17821 acgtaagttt tgaatgcggc gaatttcctg attcatcata cgcatatgac gaacagcttg
    17881 gacgatatcc cctgtccctg gttctccttt ggtacgaatc atggaagcac cttcagcgat
    17941 acgacgcaag gcttcaccca aatccttagc accacagaca aaaggaactt ggaattcttt
    18001 cttgtccaca tggaaacggt catcagctgg agatagaact tcactctcgt cgatataatc
    18061 aatttcaata gcctctaaaa tctgagcttc aacaaaatgc ccgattctga ccttagccat
    18121 tactggaata ctaaccgctt cttggatttc cttaatcatc tttgggtcgc tcatgcggga
    18181 aactcctcca gctgcacgaa tatcagccgg aattcgttcc aaggccatca cagctgccgc
    18241 accagcagct tctgcgatac gagcctgttc aggattctgc acatccataa taacaccacc
    18301 cttgagcatc tgtgccaagt ttttatttag ttcataacga ttttcagtca tttgttttat
    18361 cctcatcatt tgtattggta gctacctttt cattttaagt cagaacagaa tgaagcacaa
    18421 gataaaaaaa ctataattgt atggggacag attggctaaa aactatctga ccttaactta
    18481 aggccagata gctcattcat ttttattttt cagccgtaag ggcagccatt gtgatgtagt
    18541 tgtatggttt attgaagtgt ggcaagaaga agaggtctgt caatgccaat ttatcaattg
    18601 tcacatgctc ttggatagca agtgagaaca tgtggattcc catgctaatt gcaatatcat
    18661 gtgaaaccat ttgggcacca agaatttcac ggctatcttt gtcaaagaca atcttaattg
    18721 ctacttcatg gttgtcatgt ttcatgaatt ctggtttttg aagatcgtta aagcctgttt
    18781 cagttgcgtt gtaaccagca gctttcgctt tttcaagagt caaaccagtt gaaaccatgt
    18841 gaagaccgta gattgagata ccatttgaac cttgaacacc gattccttcc aattcatgtc
    18901 cacaagcgtt gtaggcacca acgataccag tgcgaacagc atttgaagca agagcgatat
    18961 agcttgtatc tttacgagca ttgtcataaa cagtcgcaca gtcaccaaca gcgtaaacgc
    19021 ctgggataga tgtttcttgt ttcttgtcta caaggaaggc accgttgcgg aagagttcga
    19081 tcttaccatc agcaagggct gtgtttggac ggaaaccaac tgcaaggata accatatcca
    19141 cgtcaaagct ttctttgtca gtaatcaagc gttcaacttt accatcacct tcgattgctt
    19201 taacagtttg acctagagcc aagcggatgt tgtgatcttc caagttcttc gccatcattt
    19261 gtgtgaagtc tttgtcatag taaccgttca agacagtatc aacgatatca acaaggacaa
    19321 cttcttttcc aagacgttca aaggcttcag caagttcaac accgatgtaa ccaccaccaa
    19381 caacggcgat acggtcgaga tgttggctct tgtcagaaag tttattgata acttcttcag
    19441 cattttggta caatttcacg aattgtacgt tttcaagagt tgctttaaat tcgcggtttc
    19501 ctttaacaat ttcaacacct tcgattggtg gcaagattgg tgtagaacct gtagcgaaaa
    19561 tcaatttctc gtatgattct ttgtgttctt ttccttcaac ttctgctgta accactttgt
    19621 tatcatagtc gattgaaaga actggtgaat tcatataaac cttagcacct ttagcttcta
    19681 atttgtcttt atcagaatag aacaagcctt cagcaccgtc aatttgttca ccaatccaaa
    19741 gagccattcc acatcctagg aaagagatgt tagagttttg gtcaaataca acaatttcgt
    19801 tctcatttcc aaaattatcc aacatggtat tgatacatgc tgtaccagcg tggttagcac
    19861 cgactacaac gattttactc ataaaaaatt tcctgccttc attctaaatt tactttacta
    19921 gtataccatt taccgttagc gtttacaagg gggggactat tatttcagca ttttttatca
    19981 aaaataattc cccatttatc ctgttttcaa gcctcatgaa ttttatgagc atatttcttg
    20041 actttttcca aattttgttt gtgaaaattc taactttatg gtattataat aacatgaaaa
    20101 taaaatgtaa gggcttcaat ttagatgatt atttgatatt gcaacttatt ttctataaga
    20161 gaaaggagtt ggtagcttga ctcttcgttc acattctgaa cggctaatgg ggactactat
    20221 cactatttca ttagtggatg agcaagccga tatctttctc caaaaatcct ttgacttgct
    20281 caaagagctt gaataccgct tcaacgccaa tagtcaagaa tctgagttga tggaaatcaa
    20341 ttatcaagca ggaatatccc ccgtcacagt tcatccagac ctgtttgagc tgatttcact
    20401 tgggttagag catagcctag cgctctctag ccacctcaat atcagcattg gtcccttaat
    20461 tcaaacctgg cgtatcggtt tttcagatgc caaggtcgcc cagcctcaag aaattgaatc
    20521 ggtgctgcct ctaatcaatc ctcatggtat cgagttagat tcttctactt ctactgtgtt
    20581 tttaaaacag aaaggaatga agatcgatct aggttgttta gccaaaggat acagtgcgga
    20641 taaggttgcc caatttctta ggaaagaggg ggtgacttct gccttgatca atctgggagg
    20701 gaatatcctg accattggaa aaaatcaggc aagaggggat aacccatggc aaatcgggat
    20761 tcaagaccca gccaatccta ggggaaatca tttaatgacc atccctgttg tcaataaatc
    20821 tgtcgtgact tcaggcattt atgaacgtca cctgaccgtc gatggacaag attaccatca
    20881 catttttgac agtcaaacag gatatcctgt tgaaacggaa ctagcgagtc taacaatcat
    20941 ctctgataaa tcagtcgatg gcgaaatctg gacgactcga ctctttggag aaagacctgc
    21001 ttctatcctc tggcaagtcg aaagtttgga gggcatcgaa gtcatcctca tcgataaaga
    21061 aggccaccta agctgttctt caggaattcc tactctatag agacaactgt ttcaatggaa
    21121 ttttaaaatt gtattatgta aaaagagaaa ggaaatatca tgttaaaact tattgctatt
    21181 gttggaacaa attcaaaacg ttctacaaac cgtcaattgc ttcaatacat gcaaaaacac
    21241 tttgctgaca aagctgaaat tgaacttgtt gaaatcaaga ccattcctgt cttcaacaaa
    21301 ccagctgaca agcaagtacc tgctgaaata ttggaaattg ctgctaaaat cgaagaggca
    21361 gatggcgtta ttatcggtac tcctgagtat gatcactcta ttccagctgt tttgatgagc
    21421 gctcttgctt ggttgtctta tggtatttac ccacttttga acaaaccaat catgattaca
    21481 ggtgcttctt acggtacgct tggttcatct cgtgcccaat tgcaacttcg tcaaatcttg
    21541 aatgctcctg aaatcaaggc aaatgttctt ccagatgaat tcttgctcac acactctctt
    21601 caagcattta acccaagtgg cgacttggtt gaccttgatg ttatcaagaa attggatgcc
    21661 atctttgatg acttccgtat cttcgtgaag attactgaga aattgcgcaa tgcgcaagaa
    21721 ttgcttcgca aagatgctga agactttgac tgggaaaatt tgtaagatag gagaccgaaa
    21781 gaatgaaatt tgttggactt gttggatcaa actacgatca atcatataac cgcaaactct
    21841 tggaatttat ccgtcgcaat ttcaaattca aatttgaatt agaagtactt gaaatcgacg
    21901 aagttccaat gtttaaccaa gacgaaaaat gggacgaaag cttccaattg cgtttcttgt
    21961 ataacaagat tacacgtgct gatggtgtca ttatcgccac tcctgagcac aaccacacta
    22021 tctcagcttc actcaaatct gtacttgaat ggctttcata cgaagttcat ccatttgaaa
    22081 acaagcctgt tatgattgtg ggtgcatcat actatgacca aggaacatca cgtgctcaag
    22141 ttcaccttcg taaaatcctt gatgctccag gtgttaatgc ctacacgctt ccaggtaacg
    22201 aattccttct tggtaaagct aaggaagctt ttgataacaa cggaaatatc accaacgaag
    22261 gcactgttaa attccttgaa acttgcttag ataactttgt taaatacgta ggagtcgttt
    22321 cgaaattgaa aaaaccaaaa ccaatcgaat cagaagactt ggattgtgga aaaccaatcg
    22381 ctacaaccat cacagaagtt gaccctgacg atccagaatg ggtagaaaaa gttgcagcaa
    22441 tcactggtgc tgtttctggt gatacctatg tcaaattgga ccacggtatc ctaacagtta
    22501 accaaattga tatgttcttg aaagctatgc catttgaatt gacatacgct gacgacaaca
    22561 accaattcct ctactacaac aacgctcacc aagatccaga cactatgttc gctaaacgtg
    22621 taccacctca atcaggtagc cgtatgtcga ctgttcatgg ttctcttcca ccagcacgta
    22681 tgaagaacgt agagtgggtt atcggaacac ttcgcaacgg aaaccaagaa tacgtccgta
    22741 cgatcgttcc aggttctcct gcaggtgtta tcaacactca caactaccaa gcaatgtact
    22801 atcctgatgg atcatacgct ggtatcaatg aaatcgtctt taacttccaa ccatggcttg
    22861 actggtacct aaaagagact ggtcaacgtt tggtgggtgg tagcggacca tttgctcctg
    22921 ctgccggagg tcatggagac gccgatgcta cttctggcgc ttctgattca ggggatgctg
    22981 gaggccacgg tggtgacgca gacgctacag ccggtgcaag tta
//
LOCUS       DAVBDR010000029        22953 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.029, whole genome shotgun sequence.
ACCESSION   DAVBDR010000029 DAVBDR010000000
VERSION     DAVBDR010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22953)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22953)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22953
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.029"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            complement(76..525)
                     /locus_tag="VQ540_001197"
     CDS             complement(76..525)
                     /locus_tag="VQ540_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HET2545008.1"
                     /translation="MTLTTFLLQAVASFLAIITFLIVLNVQRSMLLPGGILGMTVWLI
                     YLLLKEPTNVIVATFIAAIIGSCVSQILSILYKTPAVVFILAILAPLVPGYLSYRTTA
                     FFVTGDYNKALASATLVVMLALVISIGMASGTVILRLYHYIKTHRVS"
     gene            complement(527..1285)
                     /locus_tag="VQ540_001198"
     CDS             complement(527..1285)
                     /locus_tag="VQ540_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HET2545009.1"
                     /translation="MEESKELNAVIDVIMLAGTILLKSGSEIHRVEDTMIRIAHSQGI
                     VDCNVLAMPAAIFFSIENTNISRMKRVTSSSYNIEKVCDVNQISRQLVGGQIDLETAF
                     KQLTALQAQPLPYTKLQVTLAATFSAPFFSVMFSGNIYDALGAGVATLFGFAFSLYVE
                     KFIRIPFVTAFAGAFVFGIIAQFWARYTGFPSTADLIIAGAVMPFVPGIALTNAVRDI
                     MTNHINSGMSKMFESLLITLALGAGTSVALVLMN"
     gene            complement(1400..3379)
                     /gene="pknB"
                     /locus_tag="VQ540_001199"
     CDS             complement(1400..3379)
                     /gene="pknB"
                     /locus_tag="VQ540_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HET2545010.1"
                     /translation="MIQIGKIFAGRYRIVKQIGRGGMADVYLAKDLILDGEEVAVKVL
                     RTNYQTDPIAVARFQREARAMADLDHPHIVRITDIGEEDGQQYLAMEYVAGLDLKRYI
                     KEHYPLSNEEAVRIMGQILLAMRLAHTRGIVHRDLKPQNILLTPDGTAKVTDFGIAVA
                     FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAV
                     TIALQHFQKPLPSVIAENPSVPQALENVIIKATAKKLTNRYRSVSEMYVDLSSSLSYN
                     RRNESKLIFDETSKADTKTLPKVSQSTLTSIPKVQAQTEHKSIKNPSQAVTEETYQPQ
                     APKKHRFKMRYLILLASLVLVAASLIWILSRTPATIAIPDVAGQTVAEAKATLKKANF
                     EIGEEKTEASEKVEEGRIIRTDPGAGTGRKEGTKINLVVSSGKQSFQISNYVGRKSSD
                     VIAELKEKKVPDNLIKIEEEESNESEAGTVLKQSLPEGTTYDLSKATQIVLTVAKKAT
                     TIQLGNYIGRNSTEVISELKQKKVPENLIKIEEEESSESEPGTIMKQSPGAGTTYDVS
                     KPTQIVLTVAKKVTSVAMPSYIGSSLEFTKNNLIQIVGIKEANIEVVEVTTAPAGSVE
                     GMVVEQSPRAGEKVDLNKTRVKISIYKPKTTSATP"
     gene            complement(3376..4116)
                     /locus_tag="VQ540_001200"
     CDS             complement(3376..4116)
                     /locus_tag="VQ540_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HET2545011.1"
                     /translation="MEISLLTDVGQKRTNNQDYVNHYVNRAGRTMIILADGMGGHRAG
                     NIASEMAVTDLGVAWVDTQIDTVNEVREWFAHYLEIENQKIHQLGQDEAYRGMGTTLE
                     VLAIIDNQAIYAHIGDSRIGLIRGEEYHQLTSDHSLVNELLKAGQLTPEEAEAHPQKN
                     IITQSIGQKDEIQPDFGTVILESGDYLLLNSDGLTNMISGSEIRDIVTSDIPLADKTE
                     TLVRFANNAGGLDNITVALVFMNEEDAE"
     gene            complement(4131..5444)
                     /gene="rsmB"
                     /locus_tag="VQ540_001201"
     CDS             complement(4131..5444)
                     /gene="rsmB"
                     /locus_tag="VQ540_001201"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HET2545012.1"
                     /translation="MTKVETARSLALAVLEDVFVNQAYSNIALNKHLKGSQLSAADKG
                     LVTELVYGTVARKLTLEWYLSHFIEDRDQLDSWLYVLLLMSAYQLRYLDKIPDHAVVN
                     EAVELAKLRKKGSEKLVNAVLRRILREGWPDIASIKRKNKRDSIAYSLPVWLVAKLKE
                     EYGEERAKAIFESLLVRNKASIRVTDLSRKEEIQALLEANNSLLATTGLVKEQGHFAG
                     HNLFADGAITIQDESSQLVAPTLDLQGDERVLDACAAPGGKTAHIASYLTTGQVTALD
                     LYDHKLDLIQENAQRLGVEDRVQTQKLDARKVHEFFDQDSFDKILVDAPCSGIGLLRR
                     KPDIKYNKETADFASLQEIQLEILGSVCQILGKGGIITYSTCTIVSEENFQVVKAFLE
                     SHPEFEQVKLEHECKDIMKDGCILITPELYGSDGFFISQFRKISD"
     gene            complement(5437..6372)
                     /locus_tag="VQ540_001202"
     CDS             complement(5437..6372)
                     /locus_tag="VQ540_001202"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HET2545013.1"
                     /translation="MTKLIFMGTPDFSATVLKGLLTDDRYEILAVVTQPDRAVGRKKV
                     IQETPVKQAAKEAGLSIYQPEKLSGSPEMEELMKLGADGIVTAAFGQFLPSKLLDSMD
                     FAVNVHASLLPRHRGGAPIHYALIQGDEEAGVTIMEMVKEMDAGDMISRRSIPITDED
                     NVGTLFEKLALVGRDLLLDTLPAYIAGDIKPEPQDTSQVTFSPNIKPEEEKLDWNKTN
                     RQLFNQIRGMNPWPVAHTFLKGDRFKIYEALPVEGQGNPGEILSIGKKELIVATAEGA
                     LSLKQVQPAGKPKMDIASFLNGVGRTLTVGERFGD"
     gene            complement(6385..8781)
                     /locus_tag="VQ540_001203"
     CDS             complement(6385..8781)
                     /locus_tag="VQ540_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001162119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HET2545014.1"
                     /translation="MALAKIIVDVPLMQTDQPYSYRIPEEFEGMLEVGMRVHVPFGKG
                     NRLIQGIVLGLKSQSDGEEMEQDLKDIAEVLDFSPVLTPEQLWLAEELRKSVFSYKIS
                     ILKAMLPGFLNSSYDKILYPLEGLSQEERVRLFGSEDSLAFSSLDLAKQAEMMRLTRK
                     GLLGLEYQAVDQKKVKTQSWYEVDHAQLEGVEISTRAKKKLELRDYLLSHPESASLAS
                     LLESYSREQVNFFVDQGTVTIVQKEVQRSAAYFEGIEASRPLELNPEQRQARDAVVSS
                     IGSSQPPFLLQGITGSGKTEVYLQIIQGALDKGKTAILLVPEISLTPQMTERFIARFG
                     DKVAILHSGLSNGEKYDEWRKVERGDAQVVVGARSAIFAPLKNLGVMIIDEEHEAAYK
                     QDSNPRYHAREVAILRAQYNQATLVLGSATPSLESRARAGKGVYQHLRLTQRANPLAT
                     IPEVQVIDFRDYIGQNETSNFTPPLLEAIQDRLVKKEQVVLMLNRRGYSSFVMCRECG
                     TVDTCPNCDISLTLHMDTKTMNCHYCGFSKDIPQVCPNCKSRSIRYYGTGTQKAYDEL
                     AELFPQARILRMDVDTTRKKGSHQALLDQFGRGEADILLGTQMIAKGLDFPNVTLVGV
                     LNADTALNLPDFRSSERTFQLLTQVAGRAGRAEKAGQVLIQSYNSQHYAIRFAKDQDY
                     EGFYAYEMGIRRQLGYPPYYFTIGITLSHKKEEEVFKRAYEVMNILRSGLSETSPILG
                     PTPKPIARTHNLYHYQILIKYRLEDELGPTLNQVLALTQERENSELRLSIDHEPQQFL
                     "
     gene            complement(8847..9161)
                     /locus_tag="VQ540_001204"
     CDS             complement(8847..9161)
                     /locus_tag="VQ540_001204"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HET2545015.1"
                     /translation="MMLKPSIDTLLDKVPSKYSLVILEAKRAHELEAGAPATQGFKSE
                     KSTLRALEEIESGNVTIHPDPEGKREAVRRRIEEEKRRKEEEEKKIKEQIAKEKEDGE
                     KI"
     gene            complement(9186..9812)
                     /gene="gmk"
                     /locus_tag="VQ540_001205"
     CDS             complement(9186..9812)
                     /gene="gmk"
                     /locus_tag="VQ540_001205"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HET2545016.1"
                     /translation="MADRGLLIVFSGPSGVGKGTVRREIFESSENQFQYSVSMTTRAQ
                     RPGEVDGVDYFFRTREEFEELIRQGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLE
                     IEVQGALQVKKKVPDAVFIFLTPPDLDELQDRLVGRGTDSAEVIAQRIEKAKEEIALM
                     REYDYAIVNDQVPLAAERVKCVIEAEHFCVDRVIGHYQEMLPKSPTTR"
     gene            complement(9942..11555)
                     /locus_tag="VQ540_001206"
     CDS             complement(9942..11555)
                     /locus_tag="VQ540_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HET2545017.1"
                     /translation="MEIMSLAIAVFAVIIGLVIGYVSISAKMKSSQEAAELMLLNAEQ
                     EATNLRGQAEREADLLVNEAKRESKSLKKEALLEAKEEARKYREEVDAEFKSERQELK
                     QIESRLTERATSLDRKDDNLTSKEQTLEQKEQSISDRAKNLDAREEQLEEVERQKEAE
                     LERIGALSQAEARDIILAQTEENLTREIASRIREAEQEVKERSDKMAKDILVQAMQRI
                     AGEYVAESTNSTVHLPDDTMKGRIIGREGRNIRTFESLTGVDVIIDDTPEVVTLSGFD
                     PIRREIARMTMEMLLKDGRIHPARIEELVEKNRQEIDNKIREYGEAAAYEIGAPNLHP
                     DLMKIMGRLQFRTSYGQNVLRHSIEVAKLAGIMASELGENAALARRAGFLHDIGKAID
                     HEVEGSHVEIGMELARKYKEPPVVVNTIASHHGDVEAESVIAVIVAAADALSAARPGA
                     RSESLESYIKRLHDLEEIANGFEGVQTSFALQAGREIRIMVNPGKIKDDKVTILAHKV
                     RKKIENNLDYPGNIKVTVIRELRAVDYAK"
     gene            complement(11746..12000)
                     /locus_tag="VQ540_001207"
                     /pseudo
     CDS             complement(11746..12000)
                     /locus_tag="VQ540_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006152757.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
     gene            complement(12004..12258)
                     /locus_tag="VQ540_001208"
     CDS             complement(12004..12258)
                     /locus_tag="VQ540_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HET2545018.1"
                     /translation="MEAVLYSTFRNHLKDYMKKVNDEFEPLTVVNKNPDEDIVVLSKS
                     EWDSIQETLRIAQNKELSDKVLRGMAQVRAGSTQVHVIEE"
     gene            complement(12496..13593)
                     /locus_tag="VQ540_001209"
     CDS             complement(12496..13593)
                     /locus_tag="VQ540_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000156376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HET2545019.1"
                     /translation="MTITGIIAEFNPFHNGHKYLLDQAEGLKIVAMSGNFMQRGEPAI
                     VDKWTRAQMALENGADLVVELPFLVSVQAADFFGQGAVDILDRLGIDSLVFGTEEVLD
                     YQKIADLYTEKGAEMEKFVKNLPDSLSYPQKTQAMWKEFAGLDFSGNTPNHVLALAYA
                     KAVAGRNIKLHPIQRQGAGYHSVNKDVDFASATALRQHQKDQDFLERFMPSVALFEQA
                     SKVIWEDYFPLLRYQILSNPDLTTIYQVNQEMAVRIKEAIKTAQSVEELVELVTTKRY
                     TKARVRRLLTYILVQARENVLPEAIHVLGFTEKVRQHLKSLKGQVNLVSRIGKEPWDA
                     MTQKADQIYQLGKPSIAEQNFGRVPIRIETN"
     gene            complement(13603..14343)
                     /locus_tag="VQ540_001210"
     CDS             complement(13603..14343)
                     /locus_tag="VQ540_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001823113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HET2545020.1"
                     /translation="MATYETFAAVYDAVMDDSLYDKWTNFSLRHLPKTKERKKLLELA
                     CGTGIQSVRFSQAGFDVTGLDLSADMLKIAEKRATSAKQKIAFIEGNMLNLSKAGKYD
                     FVTCYSDSICYMQDEVEVGDVFKDVYNALNEEGVFIFDVHSTYQTDEVFPGYSYHENA
                     EDFAMLWDTYEDEVPHSIVHELTFFIKEADGSFSRHDEVHEERTYEILTYDILLEQAG
                     FKSFKLYADFEDKEPTETSTRWFFVAQK"
     gene            complement(14663..15016)
                     /gene="rsfS"
                     /locus_tag="VQ540_001211"
     CDS             complement(14663..15016)
                     /gene="rsfS"
                     /locus_tag="VQ540_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HET2545021.1"
                     /translation="MNEKELLELVVKAADEKRAEDILALDVQDLTSVTDYFVITSSMN
                     SRQLDAIAANIREKVAQAGFKGSHVEGDAAGGWVLLDLGAVVVHIFSEEMRAHYNLEK
                     LWHEANSVDISEALA"
     gene            complement(15029..15529)
                     /locus_tag="VQ540_001212"
     CDS             complement(15029..15529)
                     /locus_tag="VQ540_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HET2545022.1"
                     /translation="MKTAFIIIDVQNILVETGFQTKSLLGKISYLQNQARSKNIEIIY
                     VQHIENSEAQTSEDWQLSALLNRKPAEKVFQKKYNSIFKETGLKEYLDKQGIEKLVLC
                     GMQTEYCVDTSVKVAFEYGYQLIVPEGAVTTFDGDDIPAETINEFYEDIWEERFADVL
                     DYKHIF"
     gene            complement(15530..16123)
                     /gene="yqeK"
                     /locus_tag="VQ540_001213"
     CDS             complement(15530..16123)
                     /gene="yqeK"
                     /locus_tag="VQ540_001213"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HET2545023.1"
                     /translation="MSYQDYINCSREALLEKMAEFLPEKRLTHCLGVERAAMELAQRF
                     GVDVEKASLAGLLHDYAKKLSNQEFLALIDRYQLDPDLKNWGNNVWHGMVGIYKIQED
                     LDLHDSEILRAIEVHTVGAGQMTDLDKVIYVADYIEHNRAFPGVDVAREIANLSLNKA
                     VAYETARTVEYLAHQGFPIYPQTLETYNAFVHYLKEN"
     gene            complement(16123..16752)
                     /locus_tag="VQ540_001214"
     CDS             complement(16123..16752)
                     /locus_tag="VQ540_001214"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HET2545024.1"
                     /translation="MTIELLTPFTKVELEPEIKEKKRKQVGILGGNFNPVHNAHLIVA
                     DQVRQQLGLDQVLLMPEYQPPHVDKKETIPEHHRLKMLELAIEGIDGLVIETIELERK
                     GISYTYDTMKILTEKNPDTDYYFIIGADMVDYLPKWYRIDELVDMVQFVGVQRPRYKV
                     GTSYPVIWVDVPLMDISSSMVRDFLAQGRKPNFLLPQPVLDYIEKEGLY"
     gene            complement(16804..17115)
                     /gene="yhbY"
                     /locus_tag="VQ540_001215"
     CDS             complement(16804..17115)
                     /gene="yhbY"
                     /locus_tag="VQ540_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HET2545025.1"
                     /translation="MSLASKQRAFLNSQAHTLKPIIQIGKNGLNDQIKTSVRQALDAR
                     ELIKVTLLQNTDENIHEVAEILEEEIGVDTVQKIGRILILFKQSSKKENRKISKKVKE
                     I"
     gene            complement(17329..18435)
                     /gene="yqeH"
                     /locus_tag="VQ540_001216"
     CDS             complement(17329..18435)
                     /gene="yqeH"
                     /locus_tag="VQ540_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000391231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HET2545026.1"
                     /translation="MEEILCIGCGATIQTTDKAGLGFTPQSALEKGLETGEVYCQRCF
                     RLRHYNEITDVQLTNDDFLKLLHEVGDSDALVVNVIDIFDFNGSVIPGLPRFVSGNDV
                     LLVGNKKDILPKSVKSGKISQWLMKRAHEEGLRPVDVVLTSAQNKHAIKEVIDKIEHY
                     RKGRDVYVVGVTNVGKSTLINAIIQEITGDQNVITTSRFPGTTLDKIEIPLDDGSYIY
                     DTPGIIHRHQMAHYLTAKNLKYVSPKKEIKPKTYQLNPEQTLFLGGLGRFDFIAGEKQ
                     GFTAFFDNELKLHRSKLEGASAFYDKHLGTLLTPPNSKEKEDFPRLVQHVFTIKDKTD
                     LVISGLGWIRVTGTAKVAVWAPEGVAVATRKAII"
     gene            complement(18438..19028)
                     /locus_tag="VQ540_001217"
     CDS             complement(18438..19028)
                     /locus_tag="VQ540_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HET2545027.1"
                     /translation="MDCFILVTKENCEKKLRKGARMAIENYIPDFAVEAVYDLTVPSL
                     QAQGIKAVLVDLDNTLIAWNNPDGTPEMKQWLHDLRDAGIGIIVVSNNTKKRVQRAVE
                     KFGIDYVYWALKPFTFGIDRAMKEFHYDKKEVVMVGDQLMTDIRAAHRAGIRSILVKP
                     LVQHDSIKTQINRTRERRVMRKITEKYGPITYKKGI"
     gene            complement(18980..19888)
                     /locus_tag="VQ540_001218"
     CDS             complement(18980..19888)
                     /locus_tag="VQ540_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HET2545028.1"
                     /translation="MVLEKQLGHGCTWIDLDLGKLNKLEDLSEIYGLDKETIEYALDR
                     NERAHMDYHRESGTVTFIYNVLDVKKDKAYYETFPMTFIVEHRRLITISNTKNAYVIE
                     QMTRYLESHDTLSIYKFLFASLEIISNAYYPVIEQMDKSRDEVNDLLRQRTTKKNLFA
                     LSDLETGMVYLTAAAKQNRILLEHIQGHALYRSFDEIEREQFDDAMIEAHQLVSMTDL
                     ISQILQQLSASYNNILNNNLNDNLTTLTIISVLLAVLAVVTGFFGMNVPLPLTDEPHA
                     WLYISLASAGLWIVLSLLLRKIAKKS"
     gene            complement(19945..20505)
                     /locus_tag="VQ540_001219"
     CDS             complement(19945..20505)
                     /locus_tag="VQ540_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel"
                     /protein_id="HET2545029.1"
                     /translation="MQKFIQAYIEKLDVTTIIENILTKVISLLLLLIVFYIAKKMLHT
                     MVQRIVKPSLKMSRHDVGRQKTISRLLENVFNYTLYFFLLYCILSILGLPVSSLLAGA
                     GIAGVAIGMGAQGFLSDVINGFFILFERQLDVGDEVVLTNGPITVSGKVVSVGIRTTQ
                     LRSEEQALHFVPNRNITVVSNFSRTD"
     gene            20644..21853
                     /gene="sstT"
                     /locus_tag="VQ540_001220"
                     /pseudo
     CDS             20644..21853
                     /gene="sstT"
                     /locus_tag="VQ540_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000713440.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
     gene            21921..22874
                     /locus_tag="VQ540_001221"
     CDS             21921..22874
                     /locus_tag="VQ540_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HET2545030.1"
                     /translation="MSISQRTTKLILATCLACLFAYFLNLSSAVSAGIIALLSLSDTR
                     RSTLKLARNRLFSMLLALAIGVLAFHLSGFHIWSLGLYLAFYVPLAYKMGWEIGITPS
                     TVLVSHLLVQESTSPDLLVNEFLLFAIGTGFALLVNLYMPSREEEIQHYHTLVEEKLK
                     DILQRFKYYLSRGDGRNRAQLVAELDTLLKEALRLVYLDHSDHLFHQTDYHIHYFEMR
                     QRQSRILRNMAQQINTCHLAASESLILAQLFSKIAGQLSQTNPASDLLDEIERYLEVF
                     RNRSLPKTREEFETRATLLQLLREAKTFIQVKVDFYQKYRQ"
BASE COUNT         6155 a         5410 c         4537 g         6851 t
ORIGIN      
        1 tattctcgca catatagaaa gcgttgttaa tttatttatc tcatttttca gaaaattctt
       61 ttatttctgt aaagtctacg atactcgatg tgtttttata taatgataca gtctgagaat
      121 cactgttccg ctagccattc caatagagat taccaaagcc aacatgacaa ccaaggtcgc
      181 acttgccagt gctttattat agtcccctgt cacaaaaaag gcagttgttc ggtaggagag
      241 ataacctgga accagcggtg ccaaaatggc caagataaag accacagcag gtgtcttata
      301 aagaatactt aaaatctggc tgacacaaga accaataatg gctgcaatga aggtagctac
      361 aatgacattg gtcggttcct tgagcaagag atagattagc cagacagtca tgcccaaaat
      421 ccctccaggt aagagcatag accgttgcac attgagtacg attaaaaaag tgataatggc
      481 aagaaaactt gctactgctt gtaataaaaa ggttgttagt gtcatattag ttcatcaata
      541 ccaaggcgac agaagttcct gcccctaaag cgagggtaat gagcagggat tcaaacatct
      601 tactcatacc agagtttatg tggttggtca taatatcacg gaccgcattg gtcaaggcaa
      661 tacctggtac aaacggcatg accgcaccag ctataatcaa atctgccgtt gaaggaaaac
      721 ctgtgtagcg agcccaaaac tgggcaatta tcccaaagac aaaggctcca gcaaaggctg
      781 tcacaaaggg aattcggata aatttttcca catagaggga aaaggcaaaa ccaaataagg
      841 tcgccactcc tgccccaagt gcgtcgtaga tatttccgct aaacataact gaaaagaaag
      901 gagcactaaa ggtcgcagcc agagttacct gcaacttagt atagggaagg ggttgagctt
      961 gcaaggccgt caattgctta aaggctgttt ctaagtcaat ctgcccccca actagctgac
     1021 gagaaatctg gttcacatcg cagacttttt cgatgttata agaagaggag gtcacgcgct
     1081 tcatgcgcga aatattggta ttttcaatag agaaaaagat agcggcaggc atggcaagga
     1141 cattgcaatc cacaatcccc tgcgaatgcg cgattcgaat catggtatct tctacacgat
     1201 ggatttctga gccactttta aggagaatag tccccgctag cataatcaca tcaatgacgg
     1261 catttaattc ttttgattct tccatgcttt cctcctttta tcaactccct ctattctatc
     1321 acaaatccgg actcaaaaaa aatctttgcc atgaaatcat gacaaagatt gattactcat
     1381 tttgattatc catctgcttt taaggagtag ctgaagttgt tttaggtttg tagattgaaa
     1441 tcttgactct agtcttattg aggtctacct tttcacctgc tctaggactt tgttcaacaa
     1501 ccatgccttc tacactacct gcaggcgctg tcgtcacttc tacaacttct atattagctt
     1561 ccttaatccc aacaatttga atcaaattgt tcttagtaaa ctccaagctg gaaccaatgt
     1621 aactcggcat ggcaacactt gtaacttttt tagctactgt caagacaatt tgagtaggtt
     1681 tactcacatc ataagtcgtt ccggcacctg gactttgttt cataatcgtt cctggttcgc
     1741 tttcgctgga ctcttcttcc tctatcttaa tcaaattctc aggaaccttc ttctgcttga
     1801 gttctgagat tacttctgta gagttccgtc caatatagtt ccctaattga atcgtcgtag
     1861 cttttttagc tactgtcaaa acaatttgag ttgccttgct caagtcatag gtcgtacctt
     1921 ctggtagact ttgcttcagg accgttccag cctcactctc attcgactct tcttcctcaa
     1981 ttttaatcaa attatctgga acttttttct cttttaattc cgcgataaca tcagaagatt
     2041 tccggccgac ataattacta atttggaagg attgtttgcc tgatgagaca accagattga
     2101 ttttcgttcc ttcttttcga ccagttccag cgccaggatc tgtacggata atccgccctt
     2161 cttccacctt ttcactagcc tctgtcttct cctcaccaat ctcaaaattg gcttttttga
     2221 gcgttgcctt ggcctctgca actgtctgac ctgccacatc tggaatggca atggttgcag
     2281 gagttctgga tagtatccaa ataagagaag ctgccaccaa tacaaggctg gccaacaaaa
     2341 tcaggtaacg catcttaaat ctatgttttt tcggtgcttg tggttggtaa gtttcctctg
     2401 tcacagcctg gcttgggttt ttgattgatt tgtgttctgt ctgcgcttga accttaggaa
     2461 tagatgtcaa ggtactctga gaaaccttcg gcaaggtctt ggtatctgcc ttgctcgttt
     2521 catcaaagat taacttactt tcatttctac gattgtagga caagctacta gacaagtcca
     2581 catacatctc tgaaaccgag cggtagcgat tggtcaactt tttagcagtt gccttgataa
     2641 taacattttc taaagcctga ggtacagatg gattttctgc aataacggac ggcaggggtt
     2701 tctggaaatg ctggagggca atggtcaccg cgctatcccc gtcataaggg atatggcctg
     2761 tcaacatctc atagaaaata atccccatgg catagatatc actctgcaca gtcgccttcg
     2821 aaccacgcgc ctgctctggt gacaagtaat gaactgagcc caacatcgag ttagtctggg
     2881 tcagacttgt ctctgcaaag gctacagcaa tcccaaagtc tgtgaccttg gcagtcccat
     2941 ctggtgtcaa aaggatattt tgaggtttca agtccctgtg aacaattcct cgagtatggg
     3001 ccaagcgcat agccaagaga atttgtccca tgatacggac tgcttcttca ttagaaagag
     3061 gataatgttc cttgatatag cgtttgaggt ccagtccagc cacatactcc atagctaggt
     3121 actgttgacc gtcttcctcg ccaatatctg ttatccgaac gatatgagga tggtctagat
     3181 ctgccatagc tctcgcttca cgctgaaaac gagctacagc tatcgggtcc gtctggtagt
     3241 tggtcctcag aaccttcact gccacttctt ccccatctaa gattaagtct ttggctaggt
     3301 agacatccgc catgcctcct cgaccaatct gtttgacaat ccgatagcgt ccggcaaaaa
     3361 tcttgccgat ttggatcatt ctgcatcctc ctcgttcata aaaacaaggg caaccgtaat
     3421 gttgtctaaa cctcctgcat tgttagcaaa acgaacaagt gtctccgttt tatctgctaa
     3481 aggaatatca ctggttacaa tatcacgaat ctcactgcct gaaatcatgt tggtcaagcc
     3541 gtcactattg agcaagagat agtcacctga ctcaaggata actgtcccaa aatcaggctg
     3601 aatttcatct ttttgcccaa tagactgggt gataatattt ttttgcggat gagcttctgc
     3661 ctcttctggt gtcaattgac cagccttgag caattcatta accaaggaat gatcgctcgt
     3721 caactgatgg tattcttctc cacgaatcaa gccgatacgc gaatcaccaa tatgagcata
     3781 gatagcctga ttatcaataa tagcaaggac ttccaaagta gttcccatgc ctctgtaagc
     3841 ttcatcctga ccaagctggt gaatcttttg attttcaatt tctaggtaat gggcgaacca
     3901 ttcacgcact tcattgactg tatcgatctg ggtatcaacc caagctacac ccaggtctgt
     3961 gaccgccatt tcactagcga tattccctgc acgatgacct cccatcccat cagctaaaat
     4021 aatcatggta cgtccagctc tattgacata gtggttgaca tagtcttggt tatttgttcg
     4081 tttctgacca acatctgtta ataatgaaat ttccatgtgt cagttccttc ctaatccgat
     4141 atcttgcgaa attgactgat gaagaatcca tcacttccat acaattcagg tgtaatgagg
     4201 atacagccgt ctttcatgat atccttacat tcatgttcta gttttacctg ctcgaactcg
     4261 ggatgactct ctaaaaaggc cttaacgact tgaaaattct cctctgagac gatagtgcag
     4321 gtgctataag ttattatacc acctttgcct agtatttgac aaacactacc taatatttct
     4381 aactgaattt cctgcaagga cgcgaaatct gccgtttctt tattgtattt gatatctggt
     4441 tttcggcgca aaagaccgat tcctgaacaa ggagcatcca ccaaaatctt atcaaaggaa
     4501 tcctggtcaa aaaactcatg cacctttctg gcatccaatt tttgagtttg aacccgatct
     4561 tcaactccca gacgttgggc attttcttga attaaatcca acttgtggtc gtacaagtcc
     4621 agagcagtaa cctgacctgt cgtaagataa gaggctatat gggctgtttt cccacctgga
     4681 gccgcacagg catcaagcac tcgctcatca ccttgtaaat caagcgtcgg agcaaccaac
     4741 tgactggact cgtcttggat ggtaatggct ccatccgcaa acaaattatg ccctgcaaaa
     4801 tgcccctgct ccttaaccag accagtggtt gctaaaaggg aattattcgc ctccaacaag
     4861 gcttggattt cctcttttcg acttaggtct gttacacgaa tactggcttt gtttcgcact
     4921 aacaggcttt caaagatggc ttttgctctc tcctctccgt attcttcctt gagtttggca
     4981 actagccaaa ctgggagaga ataggcaatg gagtcacgct tgttttttcg cttgatgcta
     5041 gcaatatctg gccagccttc acgcaagata cggcgaagga cagcgttgac caatttttca
     5101 ctgccttttt tacggagttt ggccaattcc actgcttcat tgaccacagc atgatctgga
     5161 atcttgtcca aatagcggag ttggtaggca ctcatgagaa gaaggacata gagccagctg
     5221 tctaactggt ctctgtcttc gataaagtgg gataggtacc attccagagt cagtttacgg
     5281 gctaccgttc catagactag ctcggtcact aagcccttgt ctgctgcaga gagctgactc
     5341 cccttgaggt gtttatttaa ggcaatattt gaatatgctt gattcacaaa aacatcctct
     5401 agcactgcta gagctaaact tctagccgtt tctactttag tcaccaaatc gttctcctac
     5461 agtcaatgta cgtccaactc cattgaggaa ggaagcaatg tccatcttag gcttaccagc
     5521 tggctgcact tgtttgaggg atagagcccc ttcagccgtt gcgacaatca attctttctt
     5581 gccgatagag agaatctcac ctggatttcc ctgaccttct actggtaggg cttcataaat
     5641 cttaaagcgg tcgcccttaa ggaaagtatg ggcaacaggc caggggttca ttccacgaat
     5701 ttggttaaag agttgacgat tggttttgtt ccagtccagt ttttcttcct ctggctttat
     5761 atttggagag aaggtaacct gactcgtatc ctgcggttca ggtttgatat caccagcaat
     5821 ataggcaggc agagtgtcca aaagcaaatc acgaccaact agcgccaatt tttcaaacaa
     5881 ggtgccaaca ttgtcctcat ctgtgatcgg aatgctgcga cgagaaatca tatctcctgc
     5941 atccatttcc ttaaccattt ccatgatggt cacaccagct tcctcatccc cttgaatcaa
     6001 ggcataatgg ataggcgcac caccacggtg tctaggaagg agggaggcat gaacgttgac
     6061 agcaaagtcc atgctatcaa ggagtttgct tgggagaaac tgcccaaaag cagcagtcac
     6121 aattccatct gctcctagct tcataagttc ttccatctct ggacttccag ataatttttc
     6181 aggttggtag atagatagtc ctgcttcctt ggcagcctgc ttgactgggg tttcttggat
     6241 aactttttta cgaccaacag cacggtctgg ctgggtcaca acggctagaa tttcgtaacg
     6301 gtcatctgtc aaaagtcctt ttaagactgt tgctgaaaag tcgggggtcc ccataaagat
     6361 tagttttgtc atatcttctc cttcttataa aaattgctgc ggctcatggt caatgctgag
     6421 acggagctca ctattttccc gttcttgagt caaggccaag acctggttga gggtcggccc
     6481 cagctcatct tctaaacggt atttaattaa aatctggtaa tgatagaggt tgtgggtacg
     6541 ggcaatcggt tttggcgttg gccccagaat gggactggtc tctgacaagc ctgaccgcaa
     6601 aatgttcatg acttcatagg cacgtttgaa aacctcttct tctttcttgt gagaaagggt
     6661 aataccaatc gtgaaatagt aaggtggata gccgagttgt cgtctgattc ccatttcata
     6721 ggcataaaag ccttcgtaat cttgatcctt ggcaaatcga atagcatagt gctgcgaatt
     6781 gtaggactgt atcaagactt gacctgcttt ttcagcccga cctgctcgac ctgccacctg
     6841 agtcaagagc tggaaggttc tctcagaaga acggaaatca ggcagattca aggccgtatc
     6901 cgcatttaga actccgacta gggtaacatt gggaaaatcc aaaccctttg caatcatctg
     6961 agtaccaagt aaaatatccg cttcccctcg cccaaactgg tcaagcaagg cttggtgact
     7021 acctttcttt cgagtcgtat ccacatccat cctcaaaatg cgagcttggg gaaagagttc
     7081 tgctagctca tcataagcct tctgagttcc cgtcccatag taacgaatac tgcggctctt
     7141 acagttagga cagacctgag gaatatcctt cgagaaacca caataatggc agttcatagt
     7201 cttggtatcc atatgcaagg tcagagaaat atcgcagttg ggacaagtat ccaccgtccc
     7261 acactcccga cacatgacaa agctagaata accacggcga ttgagcatga gaaccacctg
     7321 ctctttttta accagacggt cttggatagc ctctagcaaa ggaggcgtaa agtttgacgt
     7381 ctcattttgt ccgatatagt ctcgaaagtc aatcacttga acctcaggga ttgtagccaa
     7441 aggattggca cgttgggtta gacgtaagtg ttgatagacg cctttgccag cacgtgcccg
     7501 gctctctaag ctcggcgttg cagatccaag taccagagtt gcttgattat actgagcccg
     7561 taaaatagct acctctctgg catggtaacg gggattgctg tcctgcttat aagccgcttc
     7621 atgctcttca tcaataatca tgacacccag atttttcaga ggagcaaaga tagcagatct
     7681 ggcaccaaca acaacttggg catcgccacg ctccaccttg cgccattcat catacttttc
     7741 gccattggat aatcctgagt gaagaatggc taccttgtcc ccaaaacgtg ctataaaacg
     7801 ctcggtcatc tgaggagtca aggaaatctc aggtaccagc aaaatagctg tcttaccctt
     7861 atccagggca ccttggataa tctgcaagta aacctcggtc ttcccacttc ctgtaatccc
     7921 ttgaagtaga aagggaggtt gagaactgcc aatagaactc acaaccgcat cacgcgcctg
     7981 tctttgttct ggatttaact ccaaaggtct acttgcttca attccttcaa aataagcagc
     8041 cgagcgttga acttcctttt ggactatggt aacagtacct tgatccacaa agaagttgac
     8101 ttgctctcgc gagtaggact ctaacaagct agccaaggaa gcgctctctg gatgagacag
     8161 cagataatct ctcagttcca actttttctt ggcacgtgta gaaatctcaa caccttctaa
     8221 ttgggcatgg tcaacctcat accaagactg ggtcttgacc ttcttttgat cgactgcctg
     8281 atattccaga ccaagcaggc cttttctagt caaacgcatc atttcagctt gcttggcaag
     8341 gtctagtgaa gaaaaggcta gcgaatcttc tgaaccaaac aggcgtactc gttcttcctg
     8401 actcaagcct tccagaggat agagaatctt gtcatagcta gaattcagaa accctggaag
     8461 catggccttg aggatagaga ttttgtagga gaagacagat ttgcgtaact cctcagccag
     8521 ccagagttgt tctggcgtga gaacaggaga aaaatccagc acctctgcaa tatcttttaa
     8581 atcttgctcc atctcttctc catctgattg ggacttcaaa ccaagaacaa tcccttgaat
     8641 caggcgatta cccttaccaa aaggcacatg aacccgcatc ccaacttcca gcattccctc
     8701 aaattcctcc ggaatcctgt aactataggg ctggtccgtc tgcatcaagg gcacatctac
     8761 gataatctta gctagggcca tcttctcacc tcctccttgt cagtacattc ttgcaataga
     8821 aaaaataaga ttgagtcccc ccaaccttaa attttttcac catcttcttt ttctttagca
     8881 atttgctctt tgattttctt ttcttcttct tctttgcggc gtttttcttc ttcgatacgg
     8941 cgacgcactg cttcacgttt tccttctgga tctgggtgaa ttgtaacgtt tcctgattcg
     9001 atttcttcta aagcgcgaag agttgatttt tcagacttga aaccttgagt tgctggggca
     9061 cctgcttcca attcgtgggc acgttttgct tccaagatta cgagtgaata ttttgaagga
     9121 accttgtcga gcaaggtatc aatagagggt tttaacatca tttgcttgta cctattttct
     9181 aaattttatc gggtagttgg agattttggt aacatctcct gatagtgacc aatgacacga
     9241 tccacacaga agtgttctgc ttcaatcaca catttgacac gttcagcagc taggggcacc
     9301 tgatcgttga caatcgcata atcatactca cgcatgaggg caatttcttc cttggccttt
     9361 tcgattcgtt gggcaatcac ttctgcacta tctgttccac gacctaccaa gcgatcttgc
     9421 aattcatcca aatctggtgg tgtcaggaag ataaagacag catctggaac ctttttcttg
     9481 acctgaagag caccctgaac ttcaatttca aggaaaacat cgattccctt gtccaaggtt
     9541 tcattgacat aggtcagagg agttccatag tagttgccga catattctgc gtattccaac
     9601 atctgtcctt gacgaatcag ctcttcaaat tcttcacgag tacggaagaa atagtcaaca
     9661 ccgtccactt ctccaggacg ttgtgcgcgt gtcgtcatcg atacagaata ttgaaattgg
     9721 ttttcagaac tctcaaaaat ctctcttcta accgttcctt ttccaacccc tgaaggacca
     9781 gaaaaaacga ttagtaagcc tcggtctgcc attgtgtctc cttttagtca atctgtgaaa
     9841 taacatttct ctagaataat ggcaaaaagc cagattatcc tttacagtct ttctatctag
     9901 tgtaacaaaa aagcagtaat ttttcaactg ctctttctta tttatttagc ataatctact
     9961 gcacgaagct cgcgaatcac ggttaccttg atatttcctg gataatcgag attgttttca
    10021 attttcttac gaactttgtg agccaagatt gtgactttgt cgtccttgat ttttcctgga
    10081 ttgaccatga tacgaatttc acgtcctgct tgaagggcaa agctagtttg cactccttca
    10141 aagccgttag caatttcttc caaatcatgg agacgcttga tgtagctttc aagagactca
    10201 ctacgagcac ctggacgggc tgcgctcaag gcatctgctg cagcgacgat aactgctatc
    10261 acgctctcag cttcaacatc tccgtggtga ctagcaatcg tattcaccac aactgggggt
    10321 tccttgtact tacgggccaa ttccataccg atttcaacgt ggctaccttc aacctcatgg
    10381 tcaatggctt tcccgatatc gtgaaggaat ccagcacgac gggcaagagc cgcattttca
    10441 ccaagttcgc tcgccatgat accagccaac ttagcaacct caatcgaatg gcgcaaaaca
    10501 ttttgtccat atgaagtacg gaactgcaaa cgtcccataa tcttcatcaa gtctggatga
    10561 aggtttggcg caccaatttc ataggcagca gcctcaccgt attcacgaat cttattgtca
    10621 atctcttgac ggtttttctc aaccaactct tcgatacgag ctggatgtat acgaccatct
    10681 ttgagcaaca tttccatagt catacgggca atctcacgac gaatcggatc aaatcctgac
    10741 aaggtcacca cttctggtgt atcgtcgata atcacatcga cccctgtcaa actttcaaag
    10801 gtacgaatgt tacgaccttc acgaccaata atgcgtccct tcatagtatc gtctggcaga
    10861 tgaactgttg agtttgttga ctccgctaca tattcaccag cgatacgttg catagcttga
    10921 accaagatgt ccttggccat tttgtcagaa cgttccttga cctcttgctc agcttcgcga
    10981 atgcgactgg caatctccct ggtcaagttt tcctctgtct gagccaagat aatatctcgt
    11041 gcttctgcct gagacagagc accaatacgc tctagttctg cttctttttg tctttcgact
    11101 tcctctaatt gctcttcacg cgcatcaagg tttttcgctc tatcagaaat actttgttct
    11161 ttttgttcaa gtgtttgttc tttactcgtc aaattgtcgt ccttacggtc aaggctagta
    11221 gctctctctg tcaaacgact ttcgatttgt ttgagttctt gacgttctga tttgaattca
    11281 gcgtccactt cttcacggta ttttctggct tcttctttgg cctccaatag tgcttctttt
    11341 ttaagagact tgctttcacg tttggcttca ttaacaagta aatccgcttc acgctcagct
    11401 tgtccacgta aattagttgc ttcttgttca gcatttaaaa gcatcaactc tgcagcttcc
    11461 tgagatgatt tcatcttagc tgagatgctg acatatccaa tgactaaacc aatgatgacg
    11521 gcaaaaacag caatcgcaag cgacatgatt tccatgtttt tacctcattt tattgttatt
    11581 ccgaatgaca tacattcttt tacattctac cataaaaaag tgattttcac aaacctaaaa
    11641 tagaatatgt tttggggaat ttggaacaca tttaccaaaa taaacttgtt gtttagaaat
    11701 agtagtttag tagagacttg agaaaaagcc tactttgcag tagacttagt aatgatcttt
    11761 aaaggacaag aaagccacgc tatctccatc catcatataa atcaagcgat tttctgcatc
    11821 aatacgccgt gaccaggctc cttggtaatc atatttgagt ggctctggtt ttcctattcc
    11881 tgtaaatgga tcgcgttgaa tatccttgat taatttattg attcttttta gtgttttttt
    11941 atcttggttt tgtcagtagc aataatctgc ccaggcatct tctgtaaact tgagtagcat
    12001 tcatcactcc tcaatcacat ggacctgagt gcttccagca cggacttgag ccattcctcg
    12061 caaaaccttg tctgataact ccttattttg ggcgattctc agggtttcct gaatactgtc
    12121 ccattcgctc tttgaaagaa ctacaatgtc ctcatctgga tttttattga ccaccgtcaa
    12181 aggctcaaat tcatcattta ccttcttcat gtagtccttt aaatgatttc ggaatgttga
    12241 gtaaaggact gcttccataa ccatacctcg ttttagctct tttccactat tatacacgaa
    12301 aagaaagaaa ttgtcaggaa cttgtacaag attttctttt ctatctattt atactcaatg
    12361 aaaatcaaag agcaaactag gaaactagcc gcaggctgta cttgagtacg gcaaggcgac
    12421 gttgacgcga tttgaatttg attttcgaag agtattattc gtaaaaaatc tcaaaaagcc
    12481 tacctttcgg tagacttagt ttgtttctat tctaatcggc actcttccaa aattttgctc
    12541 tgctatactt ggcttcccta gttggtaaat ctggtctgct ttttgggtca tagcatccca
    12601 aggttctttg ccaattcggc tgactagatt gacctgtcct ttcagagact tgagatgttg
    12661 cctgactttt tcagtaaatc caaggacatg aatggcttct ggcaagacat tttctctagc
    12721 ctgtaccaaa atataggtca ataggcgtct gacacgcgcc ttggtgtaac gtttggtagt
    12781 cactaactcg accaattctt ccacagactg ggctgtttta atagcttctt taatgcgcac
    12841 agccatttct tgattgacct gatagatggt ggttaggtcg ggatttgaca agatttgata
    12901 gcggagcaag ggaaaatagt cttcccagat caccttactg gcctgctcaa atagggcaac
    12961 agaaggcata aaacgttcta agaaatcttg gtccttctga tgttgacgga gggctgtcgc
    13021 cgaggcaaag tccacatctt tattcacaga atggtaacct gccccctgac gctgaatcgg
    13081 atgcagcttg atatttcgtc ctgcaaccgc cttggcatag gccagagcaa gaacatgatt
    13141 gggggtatta cctgaaaaat caagaccagc aaattccttc cacatagctt gggttttctg
    13201 gggataggaa agggaatcag gcagattttt cacaaatttc tccatctcag cacctttctc
    13261 tgtgtataag tcagcgattt tctggtaatc cagaacttcc tctgtcccaa aaactagact
    13321 atcaatgccc aagcgatcca agatatccac agctccttga ccaaagaaat cagctgcctg
    13381 aacactgact aaaaagggca attccactac caagtctgcg ccattttcca gcgccatctg
    13441 ggcccttgtc cacttatcca caatagcagg ctctccacgc tgcatgaaat tccctgacat
    13501 ggcaacaatt ttcagtccct ctgcctgatc cagcaggtat ttatggccat tatgaaaagg
    13561 attgaactcc gcgataatac ctgttatggt catgctaatc tcctacttct gcgccacaaa
    13621 aaaccaacgg gtgctagttt ctgttggctc cttatcctca aagtctgcat agagtttgaa
    13681 ggacttaaat ccagcctgtt ccagcaagat atcataggtc aagatctcat aggtcctctc
    13741 ctcatgtact tcatcgtggc gactaaagga accgtcagcc tccttgataa agaaagtcag
    13801 ctcatgcacg atggagtgag gaacttcgtc ctcatatgta tcccaaagca tggcaaaatc
    13861 ttccgcattt tcatggtagg aatagccagg gaatacttca tctgtctggt aggtcgagtg
    13921 cacgtcaaag atgaaaactc cctcttcatt cagcgcattg tacacgtcct taaagacgtc
    13981 ccctacttcc acctcatcct gcatatagca gatagagtcc gaataacacg tgacaaaatc
    14041 gtatttccct gccttggaca aattcagcat attaccttct ataaaagcaa tcttttgctt
    14101 ggctgaagtt gctctcttct ccgcaatctt caacatatcc gcactcaagt caagtccagt
    14161 cacatcaaaa ccagcctgag aaaagcgcac tgattgaatt cctgtcccac aagccaattc
    14221 caagagtttc tttctctcct tggtcttagg caaatgacgc agagaaaaat tcgtccattt
    14281 gtcgtataaa ctatcgtcca tgaccgcatc atagaccgcc gcaaaggttt cataagtcgc
    14341 cataaaacat gataccaagt ccgcccgtaa ttcgatagaa aattaggagc cttacgatgg
    14401 agccgagctc caaggaaggc tatctatttt ccgagaatta caggacgggt tcaaatcctt
    14461 tctaagatac aaagagcctt aaaagcaaag agtacatagg aaactttctt ccctatcgtc
    14521 agatacaaag aaagttactt tttatctcag cttttagctc gtgttcagtt tcgaaatgaa
    14581 acaaacacga ggccctttac ctttctatca atttttctaa aataagcaaa gaaacccagt
    14641 tgactacaac tgagttcatc ttctaagcaa gagcttctga aatatctact gaattcgcct
    14701 catgccatag cttctctaga ttataatggg cacgcatttc ttctgaaaag atatgcacga
    14761 caacagcacc aaggtccagt aagacccagc ctccagctgc atcgccttcg acatggctac
    14821 ctttaaagcc tgcttgagct actttttcac ggatattagc tgcgatagcg tccaactgac
    14881 ggctattcat tgagctagtg atgacaaagt agtccgtcac actagtcaaa tcttgtacat
    14941 caagtgcgag gatatcctcc gcacgtttct catcagccgc tttcacgact agttctagta
    15001 attctttttc gttcatttaa tcctcttttt agaaaatatg tttgtaatct agaacatctg
    15061 caaagcgctc ctcccaaatg tcctcataaa attcattaat cgtttctgct ggaatgtcat
    15121 ccccatcaaa ggttgtgaca gcaccttctg gaacaataag ctgatagcca tattcaaagg
    15181 caaccttgac agaggtatcc acacaatatt ctgtctgcat accacataaa actaattttt
    15241 caatcccctg cttatccaag tattctttta agccagtttc tttgaaaata ctgttatact
    15301 tcttctgaaa gaccttttca gcaggttttc gatttaaaag cgcagataac tgccaatctt
    15361 ctgatgtttg agcttcagag ttctcaatat gttgaacata gataatttca atattcttgc
    15421 ttctagcctg gttttgtaaa taagaaattt ttcccaatag actttttgtc tggaacccag
    15481 tttctactaa aatattctga acatcaatga ttataaaagc cgtcttcatt tagttctctt
    15541 tcaaatagtg cacaaaggcg ttataggttt caagggtttg gggatagatg gggaatccct
    15601 gatgagctag atactccacg gtacgagctg tttcgtaggc caccgcctta ttgagcgata
    15661 gatttgcaat ctcacgcgcc acatctactc caggaaaggc tcgattgtgc tcgatatagt
    15721 ctgcgacgta gatgacctta tctaggtctg tcatttgacc agcaccgact gtatggactt
    15781 caatggctcg caggatttct gaatcatgca aatccaaatc ttcctgaatt ttgtaaattc
    15841 cgaccatacc atgccagaca ttattgcccc agtttttgag gtcagggtct agctggtaac
    15901 ggtcaatcaa ggctagaaat tcctgatttg acaacttttt agcatagtca tgaagaagac
    15961 ctgctagact tgctttctca acatctacac caaagcgctg agctaattcc atagcggcac
    16021 gctccacacc tagacaatgg gttagacgtt tctcaggtag aaactctgcc attttttcca
    16081 acaaggcctc acgggagcag ttgatatagt cttgatagga catcagtaga gcccctcctt
    16141 ctcgatgtag tctagcactg gctgaggtag gagaaagttg ggtttccgac cttgggcaag
    16201 gaagtcccgc accatgctgg acgagatatc catgagcggt acgtccaccc agataactgg
    16261 ataggaagtc cctaccttgt agcgtggacg ctgaaccccc acaaactgaa ccatgtcaac
    16321 cagttcatca attcggtacc acttaggcag atagtcaacc atgtcggcac cgatgataaa
    16381 gtaataatcc gtatctggat tcttctctgt caaaatcttc atggtgtcgt aggtgtagga
    16441 aatacccttg cgctccaact caatggtttc aatgactagg ccgtcaattc cctcaattgc
    16501 caactcaagc atcttgagac gatggtgttc agggatggtt tcctttttat caacgtgagg
    16561 aggttggtat tcaggcatga gaagaacttg atccagtccc aactgttgcc gtacttgatc
    16621 cgcaacaatg agatgggcat tgtgaacagg gttaaaattc ccccctaaaa tcccaacttg
    16681 tttgcgtttt ttctccttga tttctggctc caactctacc ttggtaaagg gagtcaatag
    16741 ttcgattgtc ataggctagt cccctttatt tctctataaa aacagttatt tggagtttcg
    16801 gtcttagatt tctttgactt tcttagaaat cttgcgattt tctttcttgc tagattgctt
    16861 aaacaaaatc aagatgcgtc ctattttttg gactgtatcc acaccgattt cttcttccaa
    16921 aatttcagct acttcgtgga tgttttcatc tgtgttttgt aagagagtaa ccttgattaa
    16981 ttcacgcgca tcaagagctt gacggacgct ggttttgatt tggtcgttga gtccattttt
    17041 cccgatttgg atgataggtt tgagggtgtg tgcctggctg ttgaggaagg cacgttgttt
    17101 tgatgctaat gacataattt tcttccttgt tttttgatag ttattttagg tggtgaggga
    17161 cggtcggaac taattttcca aagatttcat ctttgaaaaa tggatttcct gacctcacaa
    17221 ttgagccttg gtctcaattg tgccccttgc caatctacag attggcaatc acaccacggc
    17281 aataactatc gctatatgag ctcactttgt tcgctcagcg attttgtttt aaataattgc
    17341 ttttcgtgtg gcgacggcga cgccttctgg tgcccagacg gcgacttttg ctgtgcctgt
    17401 tacacgaatc cagcctaggc ctgaaatgac taggtctgtc ttatctttaa tggtaaagac
    17461 atgctggact agccttggga aatcttcttt ttccttgcta tttggtggtg tcagaagagt
    17521 tcccaggtgc ttatcgtaga aagcactagc tccttcaagc ttgctacgat ggagtttgag
    17581 ttcattatca aagaaagcag taaatccttg cttttctcct gctataaagt caaagcgtcc
    17641 caaaccacct aaaaataggg tttgctcagg attaagctga taggtcttag gcttgatttc
    17701 ctttttagga ctgacatact tgaggttttt ggccgtcaag tagtgagcca tctggtggcg
    17761 gtggataatt cccggcgtat cgtaaatata agatccgtcg tcaagcggaa tctctatttt
    17821 gtccaaggtt gtccctggga agcgtgaagt agtgatgaca ttctgatcac ccgtgatttc
    17881 ttggataata gcattgatta gagttgattt tccaacgttg gtcacaccga ccacatagac
    17941 atcgcggccc ttacggtagt gttcaatctt atcaatgact tccttaatgg catgtttatt
    18001 ttgtgctgaa gttaggacca catcgactgg acgaagacct tcttcatggg cacgtttcat
    18061 gagccactgg ctaatcttac cagacttaac tgacttagga aggatatctt ttttatttcc
    18121 taccaagagg acatcattgc ccgagacgaa acgtggtaaa cctgggatga cagatccatt
    18181 aaaatcaaag atatcaatga cattgaccac taaggcatca ctgtctccca cctcgtgcaa
    18241 gagcttgagg aaatcatcgt tcgtcaactg gacatctgtg atttcattgt agtggcggag
    18301 acggaaacag cgttggcaat agacttcgcc agtctccaaa cctttttcaa gtgccgactg
    18361 gggggtaaaa ccaagaccag ctttatctgt cgtctgaatg gttgctccac aaccaataca
    18421 gagaatttct tccatagtta aattcctttt ttatatgtaa tcggtccgta cttttcagtg
    18481 atttttctca taacacgacg ctcacgagtt cggttaatct gcgttttgat tgagtcatgt
    18541 tggaccaagg gtttgactaa aattgaccga atccctgcac ggtgggctgc tcgtatatct
    18601 gtcatgagct ggtcgccaac catgaccact tcctttttgt catagtggaa ttccttcatg
    18661 gcacggtcaa taccaaatgt gaagggcttc aaggcccagt aaacgtaatc aatcccaaat
    18721 ttctcaactg ctcgttgaac gcgttttttg gtgttatttg acactacgat aatgccaata
    18781 cccgcgtccc gaaggtcatg tagccattgc ttcatctctg gcgttccatc agggttgttc
    18841 caagcaatga gggtattatc caaatcgacc aaaacagcct tgattccctg cgcctgcagg
    18901 cttgggactg tcagatcata gactgcttcc acagcaaaat ctggtatata attttcaatc
    18961 gccattctgg ctccttttct taactttttt tcgcaatttt ccttagtaac aaggataaaa
    19021 caatccacaa acctgcacta gccaaactga tatagagcca agcatggggc tcatctgtta
    19081 aaggtaaggg aacattcatt ccgaaaaagc ctgtcacgac tgccaaaaca gctagcaaga
    19141 ctgaaatgat agtcaaggtt gtcaaattgt cattcagatt attgtttaga atattgttgt
    19201 aagaggctga aagctgctgt aaaatctgag agattaggtc tgtcatggat accagctgat
    19261 gagcctcaat catggcatca tcaaactgtt ctctctcaat ctcatcaaaa ctacgataca
    19321 aggcatgacc ttgaatatgc tctaacaaaa tccgattttg tttggcagct gccgtcagat
    19381 aaaccatacc agtctccaaa tcagacaggg caaagaggtt tttcttggta gttcgctggc
    19441 gcaagaggtc attgacctca tccctactct tgtccatctg ctcaatgaca ggatagtagg
    19501 cattgctgat gatttccaga ctggcaaaga gaaacttata aatcgaaagc gtgtcatggc
    19561 tctccagata acgagtcatc tgttcaatga cataggcgtt cttggtatta ctaatggtaa
    19621 tcaggcgacg atgctcgacg ataaaggtca tgggaaaagt ctcatagtag gccttgtcct
    19681 tttttacgtc taggacatta tagataaagg taaccgtccc actttcacgg tggtagtcca
    19741 tgtgggcgcg ctcgtttcta tccagtgcgt attcaatggt ttccttgtcc aaaccgtaaa
    19801 tttcagaaag gtcttctagt ttattcaact ttcctaggtc taggtctatc caggtacaac
    19861 catggcccaa ctgcttttct aaaaccatct tttctcctta ttaaactccc tctattgtac
    19921 cacaaattac ttaaaataac aggtctagtc tgtgcgtgag aaattgctaa caactgtgat
    19981 atttcggtta gggacaaagt gaagggcttg ctcctcgcta cgaagctgtg tcgtacgaat
    20041 tcccacactg acaaccttac ccgatacagt aatcggtcca tttgtcagaa cgacctcatc
    20101 tcccacatcc agttgacgtt caaagaggat gaaaaagcca ttgatgacat cagacagaaa
    20161 gccttgggct cccataccaa tcgctacccc agcaatacca gctccagcca gcaaactaga
    20221 aactggcaaa cctaaaatcg acaaaatgca gtagagtaaa aagaaatata gcgtataatt
    20281 aaacacattt tctagtaaac gtgagatggt tttttggcgt ccgacatcat gacgagacat
    20341 ttttagagaa ggtttgacaa ttctctgcac catggtatga agcatttttt tagcaatata
    20401 aaatacaatc aaaagcagta aaagagaaat gaccttggtt agaatattct cgataatggt
    20461 tgtcacatct agcttttcaa tataagcctg aataaatttt tgcatataaa actcctttat
    20521 ttcattatac catattttca tcagtctcat tctccataaa tattcaaaaa atagacagaa
    20581 aattcttgat tttgtctatc atttatacta taatcataat cactacacaa aaaggagatt
    20641 attatgaaaa gaatcattca tgcttggaat aaggcaagcc ttgtcaagcg tatcttgatt
    20701 ggtatgcttt gtggggaatc ctaggactga cccttcctaa tctctcaggg attgggctac
    20761 tcggggattt attcgttgga ggtctaaaag ctgttgctcc tatcctagtc tttgctctcg
    20821 ttgccaatgc cctttcccaa catcaaaagg gacaagatag caatatgaaa actgttgttt
    20881 tcttgtatat cctatgatag ggactttcgc cgctgctctt gtagctgtac tagcaagttt
    20941 catcgtccct attgaaatta ccctaaatag tgccaatact gaaattgcac caccagatgg
    21001 gattgggcag gtcctcagca acctcttgct caaactggtt gacagcccag tcaacgccct
    21061 gcttactgct aactatattg gaatcttatc ttgggcagtc atttttggaa tcgctatgag
    21121 agaagccagt aaaaatagta aagaattgct aaaaactatc gctgacgtga cttctaaaat
    21181 tgtcgaatgg atcatcaatc tgactccatt tggaatcctt ggtcttgttt ttaaaaccat
    21241 ttctgacaag ggagtcggaa ggcttgccaa ctacggtatt ttattggttc tattagtaac
    21301 gactatgctt tttgttgccc ctgtggtcaa ccctttgatt gccttcttct ttatgagacg
    21361 caatccttac cctctagttt ggaactgcct ccgtgtcagc ggtgtgacag cctttttcac
    21421 tcgtagttct gcggctaaca ttcctgtcaa tatgaaactc tgccatgacc ttggactcaa
    21481 cccagatacc tattctgttt ctatcccact cggttctact atcaatatgg ctggagtagc
    21541 gattaccatt aaccttttga cccttgttac agttaacact cttggaattc ctgttgactt
    21601 tgccacagcc tttgtcctca gtgtggtagc agctatctca gcctgtggtg cttcaggtat
    21661 tgccggaggt tccctccttc ttatcccagt tgcttgtagc cttttcggta tttctaacga
    21721 tattgccata caaattgttg gggttggttt tgtgattggt gtcatccaag actcatgtga
    21781 aacagccctt aactcttcta cagatgtcct ctttaccgcc gttgccgaat acgcagcaac
    21841 ccgtaaaaaa taactcatca aggcaagcct gctcatgtct tgtcttttac gcttttattc
    21901 taacttatta ggaaattctt atgtctatta gccaacgtac gaccaagctc atcttagcta
    21961 cctgtcttgc ctgcctgttt gcttattttc tcaatctttc gtcagcagtt tcggctggaa
    22021 ttatcgctct cttgagccta tctgatacgc gtagaagtac tttaaaactg gctcgcaatc
    22081 gtcttttttc tatgcttcta gctctggcta tcggtgttct agcttttcac ttgagcggat
    22141 ttcatatctg gagtctcggc ctctatctgg ccttctacgt tcctttagcc tacaagatgg
    22201 gctgggaaat tggcatcaca ccaagcacgg ttttggttag ccatctcttg gttcaagagt
    22261 caacctctcc agacctccta gtcaacgaat tccttctctt tgctatcggt acaggatttg
    22321 ccttgcttgt taatctctat atgccttcac gagaagagga aatccagcac taccacacgc
    22381 tggtggaaga aaagttaaaa gatatcctcc agcgcttcaa atactattta tccagaggag
    22441 acggacgcaa ccgagcacag ctggtagcag aattagacac gcttttgaaa gaagccctca
    22501 gactggtcta tttggatcac tctgaccacc tctttcacca gaccgactac catatccact
    22561 actttgagat gagacaacga caaagtcgta tcctgagaaa catggcccaa cagattaaca
    22621 cttgtcacct tgccgccagt gaaagcctga tcttagcgca actcttttca aaaattgcag
    22681 gtcaactgag ccagaccaat cctgcttctg atttgctaga tgaaattgaa cgttatctgg
    22741 aagtcttccg gaaccgcagt ctgcccaaga caagagaaga atttgaaacc cgcgccaccc
    22801 ttcttcaact cctacgtgaa gccaaaacct tcatccaagt aaaagttgat ttttaccaaa
    22861 aatatagaca gtaatactct tcaaaccacg tcagcgtcgc cttgctgtat atatgttact
    22921 gacttcgtca gttctatcca caacctcaaa acg
//
LOCUS       DAVBDR010000030        22530 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.030, whole genome shotgun sequence.
ACCESSION   DAVBDR010000030 DAVBDR010000000
VERSION     DAVBDR010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22530)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22530)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22530
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.030"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            complement(171..395)
                     /locus_tag="VQ540_001222"
     CDS             complement(171..395)
                     /locus_tag="VQ540_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory secretory protein Asp5"
                     /protein_id="HET2545031.1"
                     /translation="MIEMLIVLAIILSLALIVLVTIQPRQNQLFSMDATSNIGKPSYW
                     QSNTLVKVLTLLVSLALFVLLLTFMVITYK"
     gene            complement(400..579)
                     /gene="asp4"
                     /locus_tag="VQ540_001223"
     CDS             complement(400..579)
                     /gene="asp4"
                     /locus_tag="VQ540_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001287962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory secretory system protein Asp4"
                     /protein_id="HET2545032.1"
                     /translation="MSEEDLFYKDVEGRMEELKQKPIKKEKETRGEKISKTFSLLLGL
                     MILIGLLFTLLGILR"
     gene            complement(581..1918)
                     /gene="gtfB"
                     /locus_tag="VQ540_001224"
     CDS             complement(581..1918)
                     /gene="gtfB"
                     /locus_tag="VQ540_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system glycosylation chaperone
                     GtfB"
                     /protein_id="HET2545033.1"
                     /translation="MIELYDSYSQESRDLHESLVATGLSQLGVVIDADGFLPDGLLSP
                     FTYYLGYEDGKPLYFNQVPVSDFWEILGDNQSACIEDVTQERAVIHYVDGMQARLVKQ
                     VDWKDLEGRVRQVDHYNRFGACFAKTTYSADSEPIMTVYQDVNGQQVLLENHVTGDIL
                     LTLPGQSMRYFANKVEFITFFLQDLEIDTSQLIFNTLATPFLVSFHHPDKSGSDVLVW
                     QEPLYDAIPGNMQLILESDNVRTKKIIIPNKATYERALELTDEKYHDQFVHLGYHYQF
                     KRDNFLRRDALILTNSDQIEQVEAIVEALPDVTFRIAAVTEMSSKLLDMLRYPNVVLY
                     QNASPQKIQELYQLSDIYLDINHSNELLQAVRQAFEHNLLILGFNQTVHNRLYIAPEH
                     LFESSEVAALVETIKLALSDVDQMRQALGKQGQHANYVDLVRYQEIMQTVLGG"
     gene            complement(1911..3422)
                     /gene="gtfA"
                     /locus_tag="VQ540_001225"
     CDS             complement(1911..3422)
                     /gene="gtfA"
                     /locus_tag="VQ540_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system glycosyltransferase GtfA"
                     /protein_id="HET2545034.1"
                     /translation="MTIYNINLGIGWASSGVEYAQAYRAGVFRKLNLSSKFIFTDMIL
                     ADNIQHLTANIGFDDNQVIWLYNHFTDIKIAPTSVTVDDVLAYFGGEESHREKNGKVL
                     RVFFFDQDKFVTCYLVDENKDLVQHAEYVFKGNLIRKDYFSYTRYCSEYFAPKDNVAV
                     LYQRTFYNEDGTPVYDILMNQGKEEVYHFKDKIFYGKQAFVRAFMKSLNLNKSDLVIL
                     DRETGIGQVVFEEAQTAHLAVVVHAEHYSENATNEDYILWNNYYDYQFTNADKVDFFI
                     VSTDRQNEVLQEQFAKYTQHQPKIVTIPVGSIDSLTDSSQGRKPFSLITASRLAKEKH
                     IDWLVKAVIEAHKELPELTFDIYGSGGEDSLLREIIANHQAEDYIQLKGHAELSQIYS
                     QYEVYLTASTSEGFGLTLMEAIGSGLPLIGFDVPYGNQTFIEDGQNGYLIPSSSDHVE
                     DQIKQAYAAKICQLYQENRLEAMRAYSYQIAEGFLTKEILEKWKKTVEEVLHD"
     gene            complement(3434..5806)
                     /gene="secA2"
                     /locus_tag="VQ540_001226"
     CDS             complement(3434..5806)
                     /gene="secA2"
                     /locus_tag="VQ540_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system translocase SecA2"
                     /protein_id="HET2545035.1"
                     /translation="MFRRLGQDFQLRKVKKILKQINALKGKMSSLSDQELVAKTVEFR
                     QRLSEGESLDDILVEAFAVVREADKRILGMFPYDVQVMGAIVMHYGNVAEMNTGEGKT
                     LTATMPVYLNAFSGEGVMVVTPNEYLSKRDAEEMGQVYRFLGLTIGVPFTEDPKKEMK
                     AEEKKLIYASDIIYTTNSSLGFDYLNDNLASNEEGKFLRPFNYVIIDEIDDILLDSAQ
                     TPLIIAGSPRVQSNYYAIIDTLVTTLVEGEDYIFKEEKEEVWLTTKGAKSAENFLGID
                     NLYKEEHASFARHLVYAIRAHKLFTKDKDYIIRGNEMVLVDKGTGRLMEMTKLQGGLH
                     QAIEAKEHVKLSPETRAMASITYQSLFKMFNKISGMTGTGKVAEKEFIETYNMSVVRI
                     PTNRPRQRIDYPDNLYITLPEKVYASLEYIKQYHAKGNPLLVFVGSVEMSQLYSSLLF
                     REGIAHNVLNANNAAREAQIISESGQMGAVTVATSMAGRGTDIKLGKGVAELGGLIVI
                     GTERMESQRIDLQIRGRSGRQGDPGMSKFFVSLEDDVIKKFGPSWVHKKYKDYQVQDM
                     TQPEVLKGRKYRKLVEKAQHASDSAGRSARRQTLEYAESMNIQRDIVYKERNRLIDGS
                     RDLEDVVVDIIERYTEEVAADHYASRELLFHFIVTNISFHVKEVPDYIDVTDKTAVRS
                     FMKQVIDKELSEKKELLNQHDLYEQFLRLSLLKAIDDNWVEQVDYLQQLSMAIGGQSA
                     SQKNPIVEYYQEAYAGFEAMKEQIRADMVRNLLMGLVEVTPKGEIVTHFP"
     gene            complement(5799..6239)
                     /gene="asp3"
                     /locus_tag="VQ540_001227"
     CDS             complement(5799..6239)
                     /gene="asp3"
                     /locus_tag="VQ540_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system protein Asp3"
                     /protein_id="HET2545036.1"
                     /translation="MIITQRQSIYWGEVGGTYMYGTTVSYYLDKSVRLYNPLLPSGEI
                     LKTWFSSVNYQAARTQPQLPLLKRKQEYQLSLVFDCQPENGVYTKITFFDRYGDILEK
                     KVEKAKDFIFTYPEDSYTYQVSLLSAGFESLTFYHFSIKEIRSV"
     gene            complement(6236..7771)
                     /gene="asp2"
                     /locus_tag="VQ540_001228"
     CDS             complement(6236..7771)
                     /gene="asp2"
                     /locus_tag="VQ540_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system protein Asp2"
                     /protein_id="HET2545037.1"
                     /translation="MSKELNILQIGLANWENHYDIPENMSWYYFYPNSSKTLREIIEK
                     EDINRFHAVLIEDGQYSRDLFSYVKYFEPYTLFYNQNLQINDREVVDFLKKRCAQAID
                     FLSPQQLINDLSKSLFGGGYGDKLFPPTIQVNPNFTGAISYQGLDYVSLEGEFGQDFA
                     QLAYWAYNIMVQKTLPIELWLEYEKEGNCDFRLVIRKMWSGSVDDFFEEVIVSEKDLE
                     QALFMDSRDGDYFLSISVEARGRGTIKLGNLHQRWSRKQFGKFVLGGNILHDSKRDEI
                     NYFFHPGDFKPPLTVYFAGYRPAEGFEGYFMMKTLGCPFILFSDPRLEGGAFYLGTDE
                     LEGKVKDTITHYLDYLGFDHKDLILSGLSMGTFPALYYGASFEPHAIIVGKPLANLGT
                     IASRGRLDAPGVSNLAFDCLIHHTGGTSSQDMTELDQRFWKIFKQANFSKTTFGLSYM
                     KDEEMDPQAYEQLVSYLCNTGAKILSKGTAGRHNDDTDTNISWFLHFYRMVLETGFGR
                     EKR"
     gene            complement(7755..9335)
                     /gene="asp1"
                     /locus_tag="VQ540_001229"
     CDS             complement(7755..9335)
                     /gene="asp1"
                     /locus_tag="VQ540_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000291149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system protein Asp1"
                     /protein_id="HET2545038.1"
                     /translation="MYYFIPAWYGSERTWHADITPWYFSHFRLEFDDTFHQIRLFQEQ
                     DIDSRLLVLAYQPHLRYFLYRHGVLETDTYSVFDVMQDFHNLHTQVLSIRDIEWDDDC
                     EFIYSPFTIIVQKNGKKFAKVEHGVEGFISDIQYFEPNGQIHMHHIMDDRGFISSIIF
                     FEDGQAAYQEYLNPKGVWQFRERLKEGGQVEVNPILGYRFKMLTYQNMGDLVAEFFEN
                     YLQTYVKDQDIFMLPSHSHHDQLVLDRLPSTNPKLLSLFIGRNPQDTFRDLDVTFEKS
                     DLILVDREDSLRLLQELYPERMHQCYHLSSFDTRLRLGRSQTKKESIIYFQLDFEQGI
                     DNQALLQVLSFVAENKDTEVIFGAFAASQEQMNEVEGIVESFIQENIQSENLGKAIDY
                     GDAENPLEENQHQDLRLQFVNLNDELDLIKTLEFVRLIVDLNRHPHLYTQIAGISAGI
                     PQINLVETVYVEHLKNGYLLTDVTEFSKAAHYYTDRLKEWNESLIYSIDKIKEHTGQQ
                     FLGKLEKWIEEVKNVKGT"
     gene            complement(9345..10562)
                     /gene="secY2"
                     /locus_tag="VQ540_001230"
     CDS             complement(9345..10562)
                     /gene="secY2"
                     /locus_tag="VQ540_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000161857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system protein translocase subunit
                     SecY2"
                     /protein_id="HET2545039.1"
                     /translation="MTKIYSSIAVKKGLFTLFLLFIYVLGSRITLPFVDLNTKDFLGG
                     STAYLAFSAALTGGNLRSLSIFSVGLSPWMSAMILWQMFSFSKRLGLTSTSIEIQDRR
                     KMYLTLMIAVIQSLAVSLRLPVQSSYSAILVVLMNTILLIAGTFFLVWLSDLNASMGI
                     GGSIVILLSSMVLNIPQDVLETFQTVHIPTGIIVLLALLTLVFSYLLALMYRARYLVP
                     VNKIGLHNRFKRYFYLEIMLNPAGGMPYMYVMSFLSVPAYLFILLGFIFPNHSGLAAL
                     SKEFMIGKPLWVYVYISVLFLFSIIFAFVTMNGEEIADRMKKSGEYIYGIYPGADTSR
                     FINRLVLRFSVIGGLFNVVMAGGPMLFVLFDEKLLRLAMIPGLFMMFGGMIFTIRDEV
                     KALRLNETYKPLI"
     gene            complement(10619..11524)
                     /locus_tag="VQ540_001231"
     CDS             complement(10619..11524)
                     /locus_tag="VQ540_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001292324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HET2545040.1"
                     /translation="MSELISVVVPIYNTGKYLVECVEHILKQTYQNIEIILVDDGSTD
                     NSGEICDAFMMQDNRVRVLHQENKGGAAQAKNMGISVAKGEYITIVDSDDIVKENMIE
                     TLYQQVQEKDADVVIGNYYNYDESDGNFYFYVTGQDFCVEELAIQEIMNRQAGDWKFN
                     SSAFILPTFKLIKKELFNEVHFSNGRRFDDEATMHRFYLLASKIVFINDNLYLYRRRS
                     GSIMRTEFDLSWARDIVEVFSKKISDCVLAGLDVSVLRIRFVNLLKDYKQTLEYHQLT
                     DTEEYKDICFRLKLFFDAEQRNGKS"
     gene            complement(11524..12720)
                     /locus_tag="VQ540_001232"
     CDS             complement(11524..12720)
                     /locus_tag="VQ540_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HET2545041.1"
                     /translation="MRKSIVLAADNAYLIPLETTIKSVLYHNRDVDFYILNSDIAPEW
                     FKLLGRKMEVVNSTIRSVHIDKELFESYKTGPHINYASYFRFFATEVVESDRVLYLDS
                     DIIVTGELATLFEIDLKGYSIGAVDDVYAYEGRKSGFNAGMLLMDVAKWKEHSIVNSL
                     LELAAEQNQVVHLGDQSILNIYFEDNWLALDKTYNYMVGVDIYHLAQECERLDDNPPT
                     IVHYASHDKPWNTYSISRLRELWWVYRDLDWSEIAFQRSDLNYFERSNQSKKQVMLVT
                     WSADIKHLEYLVQRLPDWHFHLAAPCDCSEELTSLSQYTNVTVYQNVLHSRIDWLLDD
                     SIVYLDINTGGEVFNVVTRAQESGKKIFAFDITRKSMDDGLYDGIFSVERPDDLVDRM
                     KNIEIE"
     gene            complement(12729..13949)
                     /locus_tag="VQ540_001233"
     CDS             complement(12729..13949)
                     /locus_tag="VQ540_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000938701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase family 8"
                     /protein_id="HET2545042.1"
                     /translation="MRNTKRAVAFAGDYAYIRQIETAMKSLCRHNSHLKIYLLNQDIP
                     QEWFSQIRIYLQEMGGDLIDCKLIGSQFQMNWSNKLPHINHMTFARYFIPDFVTEDKV
                     LYLDSDLIVTGDLTDLFELDLGENYLAAARSCFGAGVGFNAGVLLINNKKWGSETIRQ
                     KLIDLTEKEHENVEEGDQSILNMLFKDQYSSLEDQYNFQIGYDYGAAAFKHQFIFDIP
                     LEPLPLILHYISQDKPWNQFSVGRLREVWWEYSLMDWSVILNEWFSKSVKYPSKSQIF
                     KLQCVNLTNSWCVEKIDYLAEQLPEVHFHIVAYTNMANELLALTRFPNVTVYPNSLPM
                     LLEQIVIASDLYLDLNHDRKLEDAYEFVLKYKKPMIAFDNTCSENLSEISYEGIYPSS
                     IPKKMVAAIRSYMR"
     gene            complement(13980..16424)
                     /locus_tag="VQ540_001234"
     CDS             complement(13980..16424)
                     /locus_tag="VQ540_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_1767 family glycosyltransferase"
                     /protein_id="HET2545043.1"
                     /translation="MIKTIVLAGDRNYIRQLETTIKSILYHNRDVKIYILNQDIMPDW
                     FRKPRKIARMLGSEIIDVKLPEQTVFQDWEKQDHISSITYTRYFIADYIQEDKVLYLD
                     SDLIVNTSLEKLFSICLEEKSLAAVKDTDGITFNAGVLLINNKKWRQEKLKERLIEQS
                     IVTMKEVEEGRFEHFNGDQTIFNQVLQDDWLELDKEFNLQVGHDVTAFYNKWENYFNE
                     LVPPSIIHFVSYRKPWTTLIANRYRDLWWEFHDLEWTKILQHHIGEFELTSSLDKEFS
                     CLTLTNSQDLEGIEELVTALPDVVFHIAAWTDMGDKLIKLAVYDNVRLHPQIVPPVLD
                     KLKKSTNLYLDINHGSADENFLKSLQEQEKTLLAFQSTQHGELGQIVFENGKVSFMID
                     TIKDFKKNGHLTCFRQLPSLTCLTFTASQDIEQLDYLAGQLPNVVFQVAAWTAMGPKL
                     YDLSNRYPNIQLYPAISRDKLDELKEKMDAYLDINLLTSTSDIVAEMAHLSKPILAFY
                     KSQNGNNGQRLYSSEHPERMLADLQKLITKDMLEKPLDIIQVKGIDETLDYIIEHNSS
                     LVRFGDGEINMLAGHSIPYQDYDEELVSIMRDIIGQESREDLVVCLPDAFTDRFRFTS
                     WAIPFWKDHMDHYMDFYRELCSDSWYGSTFVSRPYIDFEDKSQAKAQFEKLKSIWENR
                     DLLIVEGATSRSGVGNDLFDEANSIKRIICPSHSAFSRVHEIEQEIEKYAGGRLILCM
                     LGPTAKVLSYNLCQMGYQVLDVGHIDSEYEWMKMGAKTKVKFSHKHTAEYNFDQDIEF
                     IDDETYNSQIVARILN"
     gene            complement(16434..17444)
                     /locus_tag="VQ540_001235"
     CDS             complement(16434..17444)
                     /locus_tag="VQ540_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HET2545044.1"
                     /translation="MKLHLTNLYGMAGDSTVILAQNAVQKIASQLGFREVGIYFYNIA
                     SDSPSEMNKRLDGIMASISIGDILVFQSPTWNGFEFDRLLFDKLKDMQVKIICFIHDV
                     VPLMFDSNYYLMKDYMYMYNLSDVLIVPSERMKTRLMEEGLTTKKILVQGMWDHPHDL
                     SLYTPAFKKELFFAGSLERFPDLQNWSQDTPLRVFSNKGEASSSARNLSIEGWKKDEE
                     LLLELSKGGFGLVWGTYQNDGESNQYYTLNISHKVSTYLTAGIPVIVPSSLSTAKFIV
                     DQGLGFVANSLEEVHAIVDKMNLQEYQEMTNRIKTFSYLLKEGYFTKKLLVDAIYHLG
                     VE"
     gene            complement(17473..18348)
                     /locus_tag="VQ540_001236"
     CDS             complement(17473..18348)
                     /locus_tag="VQ540_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000426741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HET2545045.1"
                     /translation="MENELISIVVPIYNVENYLRQCLDSIQKQTYPNFECIMVNDGSP
                     DHSSKICEEFVEKDSRFKYFEKANGGLSSARNLGIECSGGAYITFVDSDDWLEHDALD
                     RLYGALKKENADISIGRYNSYDETRYVYMTYVTDPDDSLEVIEGKAIMDREGVEEVRN
                     GNWTVAVLKLFKRELLQDLPFPIGKIAEDTYWTWKVLLRASRIVYLNRCVYWYRVGLS
                     DTLSNTWSEKRMYDEIGAREEKIAILASSDYDLTNHILIYKNRLQRVIAKLEEQNMQF
                     TEIYRRMMEKLSLLP"
     gene            complement(18388..19266)
                     /locus_tag="VQ540_001237"
     CDS             complement(18388..19266)
                     /locus_tag="VQ540_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exopolysaccharide biosynthesis protein"
                     /protein_id="HET2545046.1"
                     /translation="MKKNHLVGDALILTVSDQIEELDYLLESLPNICFYIAAPVQFSE
                     KIRSLETNYNVRLRTITNEEQLNFLVDTCDFLLDINHFQEVDAIVSKFVQAGKSVFAF
                     DNTVHGNQGQEVFLSSTPDKLVSRVRDYLNEVRVGTNHQEKIIQDGTWNVFKIDDKAH
                     FIVGANVICRNFENFHVSSGKLILHDGVFINNSCSFNCMERIEIGAGTMMGEGVRFYD
                     HDHIYTAEKIEKWQWTTAPIRVGRDCWIGSNVTILKGVTIGDNTIIGAGCLIRNDIPS
                     NSVVYNNGNLVVKRRD"
     gene            complement(19263..21348)
                     /locus_tag="VQ540_001238"
                     /pseudo
     CDS             complement(19263..21348)
                     /locus_tag="VQ540_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000341103.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
     gene            complement(21409..>22530)
                     /locus_tag="VQ540_001239"
     CDS             complement(21409..>22530)
                     /locus_tag="VQ540_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HET2545047.1"
                     /translation="STSASASASTSASESASTSASTSASASASTSASASASTSASTST
                     STSASTSASTSASTSASTSASTSASESASTSASTSASTSASASASISASESASTSASA
                     SASTSASASASTSASESASTSASASASTSTSASESASTSASASASTSASASASTSASA
                     SASTSASESASTSTSASESASTSASASASTSASASASTSASASASTSASASASTSASA
                     SASTSASASASTSASASASTSASASASTSASASASTSASASASTSASASASTSASASA
                     STSASASASTSASESASTSASESASTSASASASTSVSNSANHSNSQVGNASGSTGKSQ
                     KELPNTGTESSIGSVLLGVLAAVTGIGLVAKRRKRDEEE"
BASE COUNT         7117 a         4804 c         3611 g         6998 t
ORIGIN      
        1 acaacttcaa aacggtgttt tgagctgact tcgtcagttc catccacaac cttaaaacag
       61 tgttttgagc agcctgcggc tagcttccta gtttgctctt tgattttcat tgagtataaa
      121 aaagaaaact tcagaccaat ccacaaaagg tgaatatctg aagttttctt ttatttataa
      181 gtaatcacca taaaggttaa tagtagaaca aataaagcca aactcaccaa taaagtgagc
      241 accttgacca aggtgttgct ctgccagtag cttggtttac caatattact agtggcatcc
      301 atggaaaata gttgattttg acggggttgt atagttacca atacaatcaa agcaagagat
      361 aggataatag ctaaaacaat tagcatttca atcattgatc tacctcaaaa ttcccaacaa
      421 agtaaagagc aaaccaatca gaatcattaa gcccagtaaa agtgaaaaag ttttactaat
      481 cttctcccct cgggtttctt tttccttctt gatgggtttt tgtttcaact cttccatgcg
      541 accttcaacg tctttgtaaa ataaatcttc ctctgacatg ttagcctcct aaaacagttt
      601 gcattatttc ttgatatcgc accaagtcaa cataatttgc atgttggcct tgtttgccaa
      661 gtgcctgacg catttgatca acatctgaaa gggccaattt aatggtctca accaaggcag
      721 caacttcact actttcaaat agatgttctg gagcgatata aagtctattg tgaaccgttt
      781 ggttaaatcc aagaatcaag agattgtgct caaaggcctg acgcactgcc tgcaacaact
      841 cattgctgtg attgatatcc aagtaaatat ccgacagttg atacagctcc tgaatcttct
      901 gtggactagc attctggtaa aggaccacat taggatagcg aagcatgtct aagagcttag
      961 aagacatctc tgtcactgct gcgatacgga aggtaacatc aggcaaggct tctacgattg
     1021 cttctacttg ctcaatctga tctgaattgg tcaagattaa ggcatctcgt cttaggaaat
     1081 tatcacgttt gaactggtaa tgataaccca agtgcacaaa ctgatcatgg tatttctcgt
     1141 cagttaactc taaagcgcgc tcataagtcg ccttatttgg aatgatgatc ttcttagtac
     1201 gcacattatc actttccaaa atcaactgca tattacctgg aatggcatca tagagaggtt
     1261 cctgccatac caagacatcc gagccagatt tatctggatg atggaaggaa accaagaaag
     1321 gagtcgctag agtattaaag ataagctgac tggtatctat ttccaaatct tgcaaaaaga
     1381 aggtgataaa ttcaacttta tttgcaaagt aacgcatgga ctgaccaggc aaagtcaata
     1441 agatatcacc cgtcacatgg ttttccagta aaacttgttg gccattgaca tcttggtaaa
     1501 ctgtcataat cggctcgcta tctgcgctat aagtggtttt agcaaagcaa gcaccaaagc
     1561 gattgtagtg gtcaacctga cgtactcgac cttctaggtc tttccagtct acctgtttaa
     1621 ccaagcgagc ctgcattcca tcaacataat gaatgacagc cctctcctgc gtcacatctt
     1681 caatacaagc agactgatta tctcctaaaa tttcccaaaa atctgaaacg ggaacttggt
     1741 taaaatagag aggttttcca tcctcgtaac ctagataata ggtaaaagga gaaagcagac
     1801 catcaggcag aaaaccatct gcatcgatga ccactccaag ttgagaaaga ccagtagcga
     1861 ctagactttc atgtaaatct ctactttctt gactgtaact atcataaagt tcaatcatgg
     1921 agcacctcct ctactgtttt cttccacttt tctaaaattt ctttggtcaa gaagccttct
     1981 gcaatttgat aagaataggc acgcatagct tccaaacgat tttcttgata caattgacaa
     2041 atcttagcgg cataagcttg cttgatttgg tcttctacat ggtcagatga acttggaatc
     2101 aaataaccat tttgcccatc ctctataaag gtctgattac cataaggcac atcaaaacca
     2161 attagaggta gacctgaacc aatagcttcc atcaaggtca gaccaaatcc ttcgctggta
     2221 gaagccgtta agtagacctc atactggcta taaatctgcg aaagttccgc atgccccttg
     2281 agttggatat agtcctctgc ctgatgattt gcaataattt ctctaagcag agaatcttct
     2341 ccaccactac catagatatc aaaggttagt tccggtaact ccttatgagc ttcaatcaca
     2401 gctttcacaa gccaatcaat gtgcttttct ttggcaagac gtgaagccgt aatcaatgaa
     2461 aatggtttgc gcccttgact tgaatctgtc aaggaatcaa tactgcctac aggaatggta
     2521 acaatctttg gctgatgctg agtatatttg gcaaattgct cttgtagaac ttcattttgt
     2581 ctatcagtag acacgataaa gaagtcaacc ttatctgcat tggtaaactg atagtcataa
     2641 tagttattcc aaaggatata gtcctcattt gtagcatttt cactataatg ctccgcatga
     2701 acaactaccg ctagatgtgc tgtctgtgct tcctcaaaca caacctgtcc aatacctgtc
     2761 tccctatcca gaataaccaa atcagacttg ttcaaattca aagatttcat aaaggcacgc
     2821 acaaaagctt gctttccata gaaaatctta tccttgaaat gataaacttc ttccttccct
     2881 tgattcatca aaatatcata gactggagtc ccgtcttcat tgtaaaaagt tcgttggtat
     2941 aagactgcaa cattgtcctt gggagcaaaa tactcgctac aataacgcgt ataagaaaag
     3001 taatccttcc gaatcaggtt tcccttaaaa acatactcgg catgttgaac caagtccttg
     3061 ttctcatcaa ccaaataaca ggttacaaac ttatcttggt caaaaaagaa tacacgtaaa
     3121 accttgccat ttttttctct gtgactttct tcaccaccaa agtaagccaa gacatcatcc
     3181 actgtcacgc tagtaggtgc aattttgata tctgtgaaat gattataaag ccagataacc
     3241 tgattatcat caaaaccaat attggctgtt aagtgctgaa tattatcggc taaaatcata
     3301 tctgtaaaga taaacttaga ggacagattt aatttccgaa aaacaccagc acgataggct
     3361 tgagcgtatt caacaccgct actagcccaa ccaattccta aatttatatt gtaaattgtc
     3421 atattttctc ctcttatgga aaatgagtca cgatttcacc ttttggagtg acctcaacca
     3481 gccccatcag gagattacgc accatatccg cacggatttg ttctttcata gcttcaaagc
     3541 ccgcgtaggc ttcttgatag tactctacga ttggattttt ctgactagca gattgaccac
     3601 cgatagccat ggatagctgt tgtagatagt ctacctgctc tacccagttg tcatcaatgg
     3661 ctttaagcag tgaaagtcgt aaaaactgtt catataagtc atgttgatta agtaattctt
     3721 tcttttcaga aagttcttta tcaatcacct gcttcataaa gctacgaact gcagttttgt
     3781 cagttacatc tatataatct ggaacctctt taacatgaaa actaatattg gtcacaataa
     3841 agtgaaacaa taattcacga ctagcatagt gatcagccgc tacctcttct gtatatctct
     3901 caatgatatc cacaacaaca tcctctaagt cacgagaacc atctattaga cgatttctct
     3961 ctttatagac tatatcccgt tgtatattca tactttcagc atactccaga gtctgacgac
     4021 gtgctgaacg tccagcacta tcactggcat gctgagcctt ttcgactagt ttccggtatt
     4081 tacgaccttt caatacttcc ggttgagtca tatcttgaac ctgatagtct ttgtactttt
     4141 tatgcaccca agatggacca aatttcttga taacatcatc ctctaaggat acaaaaaatt
     4201 tactcatacc aggatctccc tgacgaccag aacggccacg aatttgtagg tcgatccgct
     4261 gactttccat ccgctcagtc ccaataacaa tcaagccccc aagctctgcg actcctttac
     4321 caagcttgat atccgtacca cgtcctgcca tagaggtagc cactgtcaca gcccccatct
     4381 gacctgactc ggagataatc tgagcctcac gcgccgcatt attagcattt aggacattat
     4441 gggcaatccc ttcacgaaac aagagagacg aatagagttg agacatttca actgagccta
     4501 caaaaacgag taaaggattt cccttagcat ggtattgctt gatgtactcc aaggatgcat
     4561 acactttttc aggtaaagtg atatatagat tatctggata gtcaatccgt tgtctcggac
     4621 gattggttgg aatgcgtact acagacatat tgtaagtttc aataaactct ttttccgcga
     4681 ccttacctgt ccctgtcata ccagatatct tattaaacat cttaaaaaga ctctgatagg
     4741 tgatcgaggc catagcccgc gtctcaggag ataatttgac atgttccttg gcttcaatag
     4801 cctgatggag acctccttga agtttagtca tttccattag acgccctgtt cccttatcaa
     4861 ccagtaccat ctcatttcca cgaatgatat agtccttatc tttagtaaag agcttatgag
     4921 ctcgaatcgc ataaaccaaa tgacgagcaa aagacgcatg ctcttccttg tataaattat
     4981 caatccctag gaaattctca gcagacttgg cccccttagt agtgagccaa acctcctctt
     5041 tctcctcttt aaagatataa tcctctcctt cgaccaaggt tgttacaagt gtatcaatga
     5101 tcgcatagta attagactga acacgaggag aacccgcaat aatcagagga gtttgtgcac
     5161 tatcaagcaa gatatcatca atttcatcaa taataacata gttaaacggt cgtaaaaact
     5221 taccttcttc attcgaggct aggttatcat ttagataatc aaaacctaaa ctactattgg
     5281 ttgtgtagat gatatccgaa gcatagataa gcttcttttc ttcagctttc atttccttct
     5341 ttggatcttc cgtaaatggt acaccaatgg tcaatcctag aaaacgataa acttggccca
     5401 tttcctcggc atcacgcttt gataaatact cattaggagt cacaaccatc actccttctc
     5461 ctgaaaaagc gttcaaatag acaggcatgg tagctgtcaa ggtcttacct tcccccgtat
     5521 tcatctcagc aacatttcca tagtgcatga caatagctcc catgacttga acatcatagg
     5581 ggaacatccc taaaatccgc ttatctgctt cacgcaccac agcaaaagct tcaaccaaaa
     5641 tatcgtctag actttctccc tcggaaagac gctgacgaaa ctctactgtt ttagctacta
     5701 attcttgatc cgaaagagag gacatcttgc ctttcagggc attaatctgc tttaaaatct
     5761 ttttcacttt cctaagctgg aaatcttgac ctaaacgtct aaacacttct gatctccttg
     5821 atagaaaaat gataaaaagt taaggactca aatccagcac ttaaaagaga aacttgataa
     5881 gtataactat cttctggata agtaaatatg aaatctttcg ctttttctac ctttttttct
     5941 aaaatatcac catagcggtc aaaaaaagtt atcttggtat aaactccatt ttcaggctga
     6001 caatcaaaaa ccagtgatag ttgatactcc tgctttcttt ttaataaggg aagctgaggt
     6061 tgggttcgtg cagcctggta attgacacta gaaaaccaag tctttagaat ctcaccagat
     6121 ggcaatagag gattatacag acgaacactt ttgtcaaggt aataagatac agttgttcca
     6181 tacatataag tcccaccaac ttctccccaa taaatagact gtctctgtgt aataatcatc
     6241 ttttctccct tccaaaacca gtctctaaga ccattctata aaagtgcaaa aaccaagaaa
     6301 tattggtatc tgtatcatca ttgtgtcgtc cagcagttcc tttagataaa atcttcgcac
     6361 ctgtattaca cagataagac actaattgtt cataggcttg tggatccatt tcttcatctt
     6421 tcatatagga taaaccaaag gttgtctttg aaaaatttgc ttgtttaaaa attttccaaa
     6481 aacgctgatc caactccgtc atatcttgag aacttgtccc acctgtatga tgaattaaac
     6541 aatcaaaagc taagttagag acacccggtg cgtccaaacg tccacgacta gctatagttc
     6601 ctaaattagc caagggctta ccaactatga tggcatgggg ttcaaaagaa gcaccataat
     6661 agagagccgg aaacgttccc atagaaagac ctgataaaat caaatcctta tgatcaaagc
     6721 ctaaataatc aagatagtga gtgatcgtat cctttacttt tccctctagc tcatccgttc
     6781 cgagataaaa agctcccccc tctaaacgtg gatcagaaaa taaaatgaag ggacatccaa
     6841 gagttttcat cataaagtaa ccctcgaatc cttctgcagg tcgataacct gcaaaataga
     6901 cagtcaaagg cggtttaaaa tcacctggat ggaagaaata gtttatttca tcacgcttgg
     6961 aatcatgtag gatatttcca ccaagtacaa acttaccaaa ttgttttcga ctccatcgtt
     7021 ggtgaagatt acctagtttg atagttccac gacctcttgc ttcaacagat atcgagagaa
     7081 agtagtctcc gtctcgacta tccataaaaa gtgcttgctc caagtctttt tcagatacta
     7141 ttacttcttc aaagaaatca tcaacagacc cactccacat tttacggatt actaaacgaa
     7201 agtcacaatt gccttccttc tcatattcaa gccacaactc aatagggagt gttttttgca
     7261 ccataatatt ataagcccaa taggcaagct gggcaaaatc ttgcccaaac tcaccttcca
     7321 aactgacata atccaatcct tgataagaaa tagctcctgt aaaatttgga ttgacttgta
     7381 tcgtcggagg aaagagttta tcaccatacc caccgccaaa aagagattta cttaaatcat
     7441 tgattagttg ttggggactt aaaaaatcaa ttgcttgtgc acatcgtttt tttagaaaat
     7501 ccacaacctc tctatcattt atttgtagat tctggttata gaacaaagta taaggttcaa
     7561 aatattttac ataggaaaat aagtctctgg aatactgacc atcttctatt aaaactgcat
     7621 gaaaacggtt aatatcctct ttttcgatta tttcacgaag ggtttttgat gagtttgggt
     7681 aaaaataata ccaactcata ttttcaggta tgtcatagtg attttcccaa ttggcaagtc
     7741 ctatctgtaa aatattaagt tcctttgaca tttttaacct cctctatcca tttctctaat
     7801 tttccaagaa attgttgtcc tgtgtgctcc ttaatcttat caattgaata tatcaaggac
     7861 tcattccact ccttcaacct atctgtgtaa taatgtgcag ccttagaaaa ttctgtcaca
     7921 tctgtcagca aataaccatt ttttaaatgt tccacataga cggtttcaac taggttgatt
     7981 tgaggaattc ctgcactaat cccagcaatc tgtgtgtaga gatgaggatg tctatttaaa
     8041 tccacaatca aacggacaaa ttctagtgtt tttatcaaat ctaactcatc attcaagtta
     8101 acaaactgta agcgtaagtc ctggtgttga ttttcttcca ggggattttc tgcatcacca
     8161 taatcaatcg cctttcccag attttcggat tgaatgtttt cttggatgaa agactcaaca
     8221 atcccttcaa cctcattcat ttgctcctga ctagcagcaa aggctccaaa aatcacctca
     8281 gtatccttat tttcagcgac aaaggacaag acttgaagca gagcttgatt atcaatcccc
     8341 tgctcaaaat ccagttgaaa ataaatgatg gattctttct tagtttggct tcgtcccaat
     8401 cgtaatcggg tgtcaaaaga tgataaatga taacattgat gcattcgttc aggatacaac
     8461 tcctgcaaca atcgtaaact atcctctcta tccaccaaaa tcaaatccga tttttcaaaa
     8521 gttacatcta aatccctaaa ggtatcttga ggattacgtc caatgaacag actcaacagt
     8581 ttaggattag tactaggtaa acgatctagt accaactggt catgatgaga atgagaagga
     8641 agcataaaaa tatcctgatc cttcacatac gtttgcagat aattctcaaa aaattctgcc
     8701 accagatctc ccatattttg ataggtaagc attttaaagc gataacccaa aattggattg
     8761 acttctacct gtcctccttc ttttaaacgc tctctaaatt gccaaactcc cttaggattc
     8821 aaatattctt gataggctgc ttgcccatct tcaaaaaaaa taatactcga tataaaccct
     8881 cgatcatcca tgatatggtg catatgtatt tgaccatttg gttcaaaata ctgtatatca
     8941 ctgatgaagc cttcaactcc atgttcaacc ttagcaaatt tcttcccatt tttttgaacg
     9001 ataatcgtaa agggactata aataaattca cagtcatcat cccactcaat atctctaatg
     9061 cttaaaactt gggtatggag attatgaaaa tcttgcataa catcaaaaac ggaataagta
     9121 tccgtttcta acacaccatg tctatataaa aaataacgta gatgaggctg gtaagctaat
     9181 actaatagac gagaatctat atcttgctct tgaaagagcc ggatctggtg aaaggtatca
     9241 tcaaactcta gacgaaaatg agaaaaatac catggagtga tatctgcatg ccatgttctt
     9301 tctgacccat accaagctgg aataaaataa tacataaaag tctcctaaat caaaggttta
     9361 taggtctcat ttagccttaa agccttgacc tcgtctctaa tcgtaaaaat catgcctcca
     9421 aacatcataa acaaacctgg aatcattgcc aatcgtaata acttttcatc aaacaaaaca
     9481 aaaagcatgg gaccacctgc cataaccaca ttaaagagac cacctatgac tgagaaacga
     9541 aggaccaatc gattaataaa tcgactagta tccgcacctg gataaatacc ataaatgtat
     9601 tctccagatt ttttcatacg gtctgcaatc tcttctccat tcatcgtaac aaaagcaaaa
     9661 atgatactaa ataaaaataa gaccgaaata taaacataga cccacaaagg ctttccaatc
     9721 ataaattcct ttgataaagc cgctaaccct gaatgattag ggaaaataaa tcccaacaag
     9781 atgaacaaat aagctggtac actaagaaaa ctcatcacat acatataagg catcccacct
     9841 gcaggattca acatgatttc gagataaaaa tagcgtttaa atcgattgtg taagccaatt
     9901 ttattaacag gaaccaaata gcgagctcga tacataaggg caagtaaata agaaaagaca
     9961 agggttaata aagcaagtaa cacaataatc cctgttggaa tgtgtactgt ctgaaatgtt
    10021 tccaaaacat cctgaggaat atttaaaacc atactggata ggagaatgac tatagaacct
    10081 ccaatcccca tactcgcatt taaatctgac aaccaaacaa gaaaaaatgt tcctgctatc
    10141 agcaatattg tattcattag aacaaccaat attgcagaat aggaggattg tactggcagt
    10201 ctcaagctaa ctgccaatga ttgaatgaca gctatcatca aggtcaggta cattttacgg
    10261 cgatcttgta tttctataga cgtagatgtt aaacccaacc gtttagaaaa agaaaacatc
    10321 tgccataaaa tcatagctga catccaaggg gacaatccaa cagaaaaaat tgacaaactt
    10381 cttagatttc cacctgttag ggcggctgag aaggctagat aggctgttga acctcctaaa
    10441 aaatctttag tatttaggtc aacaaaaggg agagtaatac gacttcccaa tacatagata
    10501 aacagtagaa ataaggtaaa tagtcctttt tttactgcta ttgacgaata aatcttagtc
    10561 ataaaacact cccctcacct tcattgtttg tgatatggta aataacaatt cttttatttc
    10621 aacttttacc atttctttgt tctgcatcaa aaaacaactt taatctgaaa caaatatctt
    10681 tatattcctc agtatctgtt aattgatggt attctaaagt ttgcttataa tcttttaaaa
    10741 gattgacaaa tcgaatacgc agaacggaga catccaaacc agccaagaca caatccgata
    10801 ttttcttaga aaacacttca acaatatctc ttgcccagga aagatcaaat tccgttctca
    10861 tgatgcttcc tgaacgtctt ctatacagat agagattatc gtttataaag acgattttag
    10921 aggctaaaag ataaaagcga tgcatagttg cttcatcatc aaagcggcga ccatttgaaa
    10981 agtgaacttc attgaataat tcttttttaa tcaacttaaa tgtcggcaat ataaaggccg
    11041 agctattgaa tttccaatct cctgcttgac ggttcataat ttcttgtata gctaattctt
    11101 cgacgcaaaa atcttgccct gttacataaa aataaaaatt cccgtcactt tcgtcataat
    11161 tatagtaatt ccctataaca acatctgcat ccttttcttg gacttgctga taaagagttt
    11221 caatcatatt ttcttttacg atatcatctg aatcaacaat cgtgatgtac tctcccttag
    11281 ctacactaat ccccatattt ttagcttgtg ctgccccccc cttattttct tgatgcaata
    11341 ctcgcacacg attatcttgc atcataaaag catcacaaat ttccccagaa ttatccgtag
    11401 aaccgtcatc aactaaaata atttctatat tttgataggt ttgcttcaga atatgctcga
    11461 cacactccac taaatatttt cccgtattgt atatcggtac cacaacacta attaattcac
    11521 tcattactct atctctatat tcttcattct atccactaaa tcatctggtc tctccacaga
    11581 aaaaataccg tcatagagtc catcatccat acttttacgt gtgatatcaa aagcgaagat
    11641 tttcttgcca ctttcttgtg cccttgtaac tacattaaaa acctctccac ctgtattaat
    11701 atctaaataa actatagaat cgtccaatag ccaatcaatt ctactatgta atacattttg
    11761 atatactgtt acattcgtat actgtgatag agaggtcagc tcctcagaac aatcacacgg
    11821 tgcagccaaa tgaaaatgcc aatcaggtaa ccgttgtact aaatactcta aatgttttat
    11881 atctgcactc catgtcacaa gcatcacttg ttttttagac tgattgcttc tttcaaaata
    11941 atttaaatcg gaacgttgaa aagcaatctc tgaccaatcc aaatctctat aaacccacca
    12001 taattcacgt agtctagata tactatatgt attccaaggt ttatcatgac tagcatagtg
    12061 aacaattgta ggtggattgt catctagacg ttcacattct tgagcaaggt gataaatatc
    12121 aacacccacc atataattat atgttttatc taaggctagc caattatcct caaaataaat
    12181 atttaaaata ctctgatccc caagatgaac aacttgattt tgctcggccg ctaattccaa
    12241 taaactattg acaatagagt gttctttcca ttttgcaaca tccattagta acataccagc
    12301 attaaatcca gattttcgtc cttcataggc atagacatca tcaacagcac caattgaata
    12361 tcctttgaga tctatctcaa acaaagtagc tagttcccca gttacaatga tatcggaatc
    12421 cagatacaat accctatcag attcaaccac ttctgtcgca aaaaatctaa agtaagaagc
    12481 ataatttata tgaggtcctg ttttatagct ttcaaaaagt tctttatcaa tgtgtacact
    12541 gcgaattgta gaattcacaa cttccatttt tctccccaat aatttaaacc attcaggagc
    12601 tatatcactg ttgagaatat aaaaatcaac atctctattg tgatacaata cagactttat
    12661 agtcgtctct aaaggaataa gataggcatt atctgccgct aatactattg attttctcat
    12721 actgttctct acctcatgta agatctgatt gctgcaacca tttttttcgg aatggagctt
    12781 ggatagatac cttcatatga aatctcagaa agattttcag agcaagtatt gtcgaaagct
    12841 atcattggtt ttttgtactt aagcacaaac tcatatgcat cttctaattt tcgatcatga
    12901 ttcaaatcca aatacaaatc tgaagctatt actatttgtt ccaataacat tggtaaggaa
    12961 tttggatata cggtaacatt aggaaaacgc gttaaagcta gtagttcatt tgccatattt
    13021 gtataagcaa caatatgaaa atgaacttct ggcaattgct ccgccaaata atcgattttc
    13081 tcgacacacc aagaattcgt taaattaaca cattgtaact taaatatttg tgatttacta
    13141 ggatacttca cactctttga aaaccattca tttaaaataa cagaccaatc catcaaagag
    13201 tattcccacc aaacttctct tagacgtcca acagaaaatt gattccaagg cttatcctga
    13261 gaaatatagt gtaaaattag tggcagtggt tcgagcggaa tatcaaaaat gaattgatgt
    13321 ttaaaggctg ccgccccata atcatatcct atttgaaaat tatattgatc ttcaagggaa
    13381 ctatattgat ctttaaacaa catattcaaa attgactggt ctccttcttc cacattctca
    13441 tgttcttttt ctgttaagtc aatcaatttt tgtcgaatag tttcagatcc ccattttttg
    13501 ttgttaatca agagaacacc agcattgaag ccgactcctg ctccaaagca agaacgagct
    13561 gctgccaaat aattttcacc taagtctaat tcaaacaaat cggtcaaatc accagtcaca
    13621 atcaaatcac tatctagata gagaacttta tcttctgtta caaaatctgg aataaaatag
    13681 cgtgcaaatg tcatatgatt gatatgaggt aatttattag accaattcat ttgaaactgt
    13741 gagccaatta acttgcagtc aatcaagtcg ccccccatct cttgtaaata tattcttatt
    13801 tgactaaacc attcctgagg aatgtcctga tttagcagat aaattttcaa atgactattg
    13861 tgtctacaga gtgacttcat cgccgtttcg atttgtcgaa tataagcgta atcacctgca
    13921 aatgctacag cgcgtttggt atttctcatt ttaaatcctt atcatttatt ttaaatagtc
    13981 tagtttaata ttcgtgcaac aatctgactg ttataggttt catcatcaat aaattcaata
    14041 tcttgatcaa aattatactc tgcagtatgt ttatgagaaa atttaacctt agttttagct
    14101 cccattttca tccattcata ctctgagtca atatggccta catccaaaac ttgatagccc
    14161 atctggcata gattataact cagaactttt gctgtaggac ccagcataca taaaatcaag
    14221 cgaccaccag catacttttc aatttcttgt tcaatttcat gaactctaga aaaggcacta
    14281 tgagaaggac agataattcg cttaatagaa tttgcctcat cgaataaatc atttccgaca
    14341 cctgaacgag aagtcgcacc ttcgactatc agtaagtcac ggttttccca aatgcttttc
    14401 aatttttcaa attgagcttt agcttgactc ttgtcttcaa aatcgatata agggcgagat
    14461 acaaaggttg agccatacca tgaatcactg cataactctc tgtaaaaatc catataatga
    14521 tccatgtgat ctttccaaaa tggaatcgcc cacgatgtaa acctaaaacg atctgtaaaa
    14581 gcatcaggaa ggcacactac taaatcttct cgactttctt ggccgataat gtccctcatg
    14641 attgaaacca actcttcatc ataatcctgg tagggaattg aatgccctgc aagcatattg
    14701 atttccccat ctccaaaacg aactaaagaa gagttgtgtt caataatata atccaaggtt
    14761 tcatctatcc ctttcacctg gattatatca agcggttttt ctagcatatc cttagttatc
    14821 aatttttgca aatcagccaa cattcgttca ggatgttcac ttgaatacaa cctttggcca
    14881 ttattcccat tttgagattt ataaaaggct agtataggtt tagatagatg agccatttct
    14941 gcaacgatat cggatgttga agtcagtagg ttgatatcta aataagcatc catcttctcc
    15001 ttcaactcgt ctagcttatc tctagaaatt gccggataga gctgaatatt aggataacga
    15061 ttagacaaat catataattt tggccccata gctgtccaag cagcaacttg aaaaacaaca
    15121 tttggcaact gtccagccaa gtaatccaat tgttcgatat cctgagaagc cgtaaacgtt
    15181 aaacaagtta aacttggaag ttgtcgaaaa caggtaagat gtccgttttt cttaaaatct
    15241 ttaatcgtat caatcataaa ggaaactttc ccattttcga aaacgatttg tcctaactct
    15301 ccgtgctgag tcgattgaaa agctagtagc gttttttctt gttcttgcaa agattttaaa
    15361 aagttctcat ctgcactacc atgattgata tccaaatata gatttgttga ctttttcagc
    15421 ttatctaata caggaggaac aatttgtgga tgcaatctca cattatcata cacagctaat
    15481 tttatcagct tatcacccat atccgtccaa gcagcaatat gaaataccac atctggtaaa
    15541 gctgtgacta actcttctat tccttctaaa tcttgggaat ttgtcaaagt taaacaagaa
    15601 aattccttat ctaaagacga tgtcagttca aactccccta tatgatgttg taaaatttta
    15661 gtccattcca aatcatgaaa ttcccaccat aaatcacgat aacgattggc tatcaaggtg
    15721 gtccagggtt ttctgtaaga cacaaaatga ataatactag gaggtactaa ctcattaaaa
    15781 taattttccc atttattata aaaagcagtt acatcatgac ccacttgaag gttaaattct
    15841 ttatccagct ctaaccaatc atcttgtaag acctgattaa aaatcgtttg atcaccatta
    15901 aaatgctcga aacggccttc ttcaacttcc ttcattgtaa caatgctctg ttcaattagt
    15961 cgttctttta atttctcttg acgccatttt ttattgttga ttaataaaac acctgcatta
    16021 aatgtaattc catctgtatc tttaactgct gcgagtgatt tttcttctaa acaaatacta
    16081 aataatttct ctaaagaagt atttacaatc aaatcactgt ctaaatataa aaccttatct
    16141 tcttggatat aatctgcaat aaaatatcta gtataggtaa tgctactaat gtgatcttgc
    16201 ttttcccaat cttgaaacac agtttgttca ggtagcttca catcgataat ctcactacct
    16261 aacatgcgag ctatttttcg tggtttgcga aaccaatctg gcataatatc ttgatttaaa
    16321 atataaatct taacatctcg attgtggtat aaaatagatt ttatggttgt ttctaactgc
    16381 ctgatgtaat tacgatcacc agctaataca attgttttaa tcatcttgtt ctcttattca
    16441 actcccaaat ggtaaattgc atctaccaat aattttttag taaaataacc ttcttttagc
    16501 aaataactaa aggtttttat ccgattcgtc atttcttgat attcttgtag attcatttta
    16561 tcaactatcg catgaacttc ttctagacta ttcgccacaa agcctaagcc ttgatctact
    16621 ataaatttag cagttgacaa gctacttggt acaatgactg ggatgcccgc tgtcagatag
    16681 gtactcacct tatgagatat atttaaggta taatattggt tgctttctcc atcgttttga
    16741 taagttcccc agacaaggcc aaatccaccc tttgataatt ctagcaacaa ttcctcatct
    16801 tttttccatc cttcgatgct gagatttcta gcactagaac tagcttcccc tttatttgaa
    16861 aatactctca aaggcgtatc ttgagaccaa ttttgtaagt ctggaaaacg ctctaaactt
    16921 ccagcaaaaa aaagttcttt tttaaaagca ggggtgtata aggataaatc atgaggatga
    16981 tcccacatcc cttgaacaag aatcttctta gtcgtcaatc cttcttccat caggcgtgtt
    17041 ttcattctct ctgacggcac tatcaaaaca tctgatagat tatacatgta catatagtct
    17101 ttcatgagat aatagttact atcaaacatg aggggaacaa catcatggat aaagcaaata
    17161 attttcacct gcatatcctt caacttatca aacaagagac gatcaaattc aaagccattc
    17221 caggttggag actgaaagac taaaatatcc ccaatagaaa tactggccat aataccatcc
    17281 agacgcttat tcatttcaga aggactatct gaagcaatgt tgtaaaaata aataccaacc
    17341 tctctaaatc ccagttgact agctatcttt tgaacagcat tttgagctaa gataaccgta
    17401 ctatcaccag ccatgccgta taaatttgtt aaatgtagtt tcatattacg ctatctcatt
    17461 ttttattact atctacggaa gtaaagacaa tttttccatc attcttctat aaatctctgt
    17521 gaactgcata ttttgttctt ctaattttgc tatcactctt tgtaatctat ttttataaat
    17581 caaaatatga ttggtcaagt catagtctga acttgctaaa atagctatct tttcttccct
    17641 agccccgatt tcatcataca tacgcttttc actccatgta ttcgataaag tatcagataa
    17701 accaacacgg taccagtaaa cacaacgatt caaatagact atcctcgaag ctcttagaag
    17761 taccttccat gtccagtaag tatcctctgc aatttttcct ataggaaatg gtaaatcttg
    17821 tagtaactct ctcttgaata acttcaagac agctacagtc cagttcccat ttctgacttc
    17881 ttcgacacct tccctatcca tgattgcttt accttctatc acttccagag aatcatctgg
    17941 atccgtaaca taagtcatat acacatagcg tgtttcatca taagaattat aacgcccgat
    18001 actaatatct gcgttttcct ttttcaaagc accatataat cggtctaaag catcatgttc
    18061 caaccaatca tcagagtcta caaaagtaat gtacgccccc cccgaacatt caatacctag
    18121 gttacgagct gatgaaagac cgccgtttgc tttctcaaaa tatttgaaac gagaatcttt
    18181 ctctacaaat tcttcacata ttttggatga atgatctgga gagccatcat taaccatgat
    18241 acattcaaaa ttcggataag tttgtttttg aatactatcc aaacactgtc gcaaataatt
    18301 ctcaacgttg tagattggga ctacaatact aattagttca ttttccatat actaactttc
    18361 ctagacttga tttattctat ttccctctta atctcttctc tttacaacaa gatttccatt
    18421 attataaact acactgtttg atggaatatc attgcgtatg agacaacctg ctccaataat
    18481 ggtattatcc ccaatcgtca ctccttttaa aatcgtgaca ttacttccta tccagcagtc
    18541 tctgccaact ctaatcggcg ctgtagtcca ctgccacttt tcaatctttt cagcagtata
    18601 aatatggtcg tgatcataaa aacgaacacc ctctcccatc atggtaccag ctccgatttc
    18661 aattctttcc atacagttaa aactacaaga gttgttgata aaaacaccat catgcagtat
    18721 taacttacca gaagagacat gaaaattttc aaaatttctg cagatgacat ttgctcctac
    18781 aatgaagtga gccttatcat cgattttaaa gacattccaa gtcccatctt ggatgatttt
    18841 ttcttgatga ttggtgccta ctctgacttc attcagatag tctctcactc tagaaaccaa
    18901 tttgtctggt gtacttgata gaaaaacttc ctgcccctga tttccatgga ctgtattgtc
    18961 aaaagcaaag acagattttc cagcctgtac aaacttggag acaatagcat ctacttcttg
    19021 aaagtgattg atatctagta aaaagtcaca ggtatcgact agaaagttta gctgttcttc
    19081 atttgtaatc gttcggagac ggacattata gttcgtttct aagctacgga ttttctcgga
    19141 aaattgaaca ggtgctgcaa tataaaaaca gatatttggc aaggattcaa ggagataatc
    19201 caactcttca atctgatcac taacagtcaa aatcagagca tctcctacta aatgattttt
    19261 cttcatttgc ttatttctct caatttctca atcattgctt gaacttggtc aacagcatat
    19321 acctcctgac ctgcttcata ggttttggta ttttcaaagg acaaaatagt ttttccaagt
    19381 cttgcaaatt gattgataat ttcctctgtt ttttcaccat gattaatatc taaaagtact
    19441 tgactggttt ctaccaattc attatcgaca tctaccaaat agtgaattcc gttaaatata
    19501 gtcacgtttg gataaattgt catctgagcc aatcgatcac taactattac tctagctgct
    19561 atcttaaact gaatatcagg caaggattga accaatgtct caatttgttc aatatggtct
    19621 gaggcagtat agattagaca agtgaaaggt tcctttattg gatagatgtg agatctttgt
    19681 aatggatgta aatgatggtt ttgtcccaat tctgtccatt caagcccatg atagtaccac
    19741 caaacttcac gataggtttg ggccgccaaa tctttccacg gtttccgatg agaaagatag
    19801 tgaataatag caggataatc ctgaccctca ggcaattgat aatcagcaaa ctgtttatga
    19861 atgacaatat gattataatc aaagtccaat tccaaccatt tatgttcaaa aagcatattc
    19921 aagatgctct gatctgcctg atccacctta tcatgccatt cattggttac atcaattaat
    19981 ttttgggtca tattctcttt tttccaaaaa gcattgttta ccaagagaac accggcatta
    20041 aagatttctt gaccaaaata agctctgccc ccaaaatctc taacagcagc caaaggataa
    20101 tcttgtaagt ctgtagcaaa caaatcatca agatttttcg ttacaagtaa atcacagtcc
    20161 aagtagaggg ccttatcttc ttgcacgaaa tcagctatga aatagcgtaa aaaaactgtg
    20221 taactaatat ccgttttata acatgaaatt tgctcagaag ttacccgaca attaataatt
    20281 tctgagtcaa acttctctaa gcgcttattt aattgcttaa tccattcatt tggaaaatcg
    20341 ctatgaatca gataaaaacg aatcgaacga ttatgataac aaatagactt gattgtcgtt
    20401 aaaacttggt ctacatagcc atagtttgct gctaggacaa tggctttctt ttcacttgat
    20461 tcttgtaccg ttaactgatt taaaagtctt tttttcattt caaactcttt atatattgct
    20521 gtgtcagata aaccactagc ttgaccgttg gcgagactga cttccaacat ctgacgataa
    20581 actgccaagt gtttctctag aggatatccc atattagcta gtagcgtaat acgttcagac
    20641 atagcatcaa ctaaggcgtg catccacttt tctgtccaaa ctcttgatag actacctttt
    20701 ctaatccgat aagcataaag acctttattt aaataaatta ccttttccga taataaatat
    20761 accttttgat tgaggtaacc atcttctcct aatttaccca tgtcaaagcg caactgctca
    20821 aacaatcttg ccttatagag tttaccacaa gcagatatca aagcaaaact cttcatttct
    20881 tgagtttcat aacaagttct caaagatgga aacattgtca tataccttat cataatagga
    20941 gtctcctgat atatgaaagt agaacattcc ttcactttcg ttgaaagaat agtaattccc
    21001 aactgcaata tcagcttgat attctgttat ttttttatat agggtttcta cataatctaa
    21061 ctcaatccaa tcatctgaat ccacaaaggt cacataattt ccggacatat tattcagacc
    21121 ggtgtttcgt gcggcagaaa taccagcatt ttcttgttct atatagagaa ttcggtgatc
    21181 catttctgaa aattctttac aaatttcacc tgaagcatcc gtagaaccat cattaacgac
    21241 aacaatctca atatttttat atgtttgaga aataatacta tctagacatt tcctcagata
    21301 gttttctaca ttgtatactg gtacaatgac cgtaatttta tcatccacta gcaattttct
    21361 ccttgattta tgtgcgcgag ttagtttagc ctaactttac aggttgtctt actcttcttc
    21421 atcacgttta cggcgtttcg caaccaatcc aatacctgta acagctgcta gaactccaag
    21481 taacacagat ccaattgacg actcagtacc tgtattaggc aattcttttt gggatttacc
    21541 tgtcgatcca gaagcatttc caacttgtga gttcgaatgg tttgctgaat ttgaaactga
    21601 tgtacttgct gaggctgacg cactcgttga tgctgactca gacgcactgg ttgatgccga
    21661 ttcagacgct gaggtgcttg ctgatgctga ggcactggtt gacgctgaag ctgaggcgct
    21721 agtacttgct gaagccgagg cactggttga tgctgaggct gaggcgctag tacttgctga
    21781 agctgaggca cttgtcgatg ctgaggccga agcactggta cttgctgaag ccgaagcact
    21841 cgttgatgct gaggctgaag cactggttga cgctgaagct gaggcactcg ttgaggctga
    21901 agccgaagca ctcgttgatg cggaagctga cgcactggta cttgctgaag ctgaggcgct
    21961 tgtgcttgct gaggccgagg cacttgttga ggccgattca gaagctgagg tactcgttga
    22021 tgcggattca gatgctgagg tgcttgctga ggccgaggcg ctggttgatg cagaagctga
    22081 ggcactggtt gacgctgaag ctgaggcact ggttgaggcc gattcagaag ctgaggtact
    22141 ggtgcttgct gaagctgagg cactcgttga tgccgattca gacgctgagg tgcttgctga
    22201 agctgatgca cttgttgatg ctgaggctga ggcgctggtt gatgccgatt cagacgctga
    22261 gatacttgct gaggctgagg cgcttgtact tgctgaagtc gacgcactgg ttgaggccga
    22321 ttcagatgct gacgtacttg cacttgttga cgccgatgtg cttgcacttg tcgatgctga
    22381 cgtgcttgcc gatgtacttg tgcttgttga tgctgacgtg cttgctgaag ccgaagcact
    22441 ggtgcttgct gaagccgatg cacttgtact tgctgaggtt gatgccgatt cagacgcact
    22501 cgttgatgcg gaagctgacg cactggttga
//
LOCUS       DAVBDR010000031        22287 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.031, whole genome shotgun sequence.
ACCESSION   DAVBDR010000031 DAVBDR010000000
VERSION     DAVBDR010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22287)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22287)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22287
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.031"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            complement(160..2118)
                     /gene="ftsH"
                     /locus_tag="VQ540_001240"
     CDS             complement(160..2118)
                     /gene="ftsH"
                     /locus_tag="VQ540_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HET2545048.1"
                     /translation="MKKQNNGLIKNPFLWLLFIFFLVTGFQYFYSGNNSGGSQQINYT
                     ELVQEITDGNVKELTYQPNGSVIEVSGVYKNPKTSKEETGIQFFTPSVTKVEKFTSTI
                     LPADTTVSELQKLATDHKAEVTVKHESSSGIWINLLVSIVPFGILFFFLFSMMGNMGG
                     GNGRNPMSFGRSKAKAANKEDIKVRFSDVAGAEEEKQELVEVVEFLKDPKRFTKLGAR
                     IPAGVLLEGPPGTGKTLLAKAVAGEAGVPFFSISGSDFVEMFVGVGASRVRSLFEDAK
                     KAAPAIIFIDEIDAVGRQRGVGLGGGNDEREQTLNQLLIEMDGFEGNEGIIVIAATNR
                     SDVLDPALLRPGRFDRKVLVGRPDVKGREAILKVHAKNKPLAEDVDLKLVAQQTPGFV
                     GADLENVLNEAALVAARRNKSIIDASDIDEAEDRVIAGPSKKDKTVSQKERELVAYHE
                     AGHTIVGLVLSNARVVHKVTIVPRGRAGGYMIALPKEDQMLLSKEDMKEQLAGLMGGR
                     VAEEIIFNVQTTGASNDFEQATQMARAMVTEYGMSEKLGPVQYEGNHAMFGAQSPQKS
                     ISEQTAYEIDEEVRSLLNEARNKAAEIIQSNREIHKLIAEALLKYETLDSTQIKALYE
                     TGKMPEAVEEESHALSYDEVKSKMNDEK"
     gene            complement(2134..2676)
                     /gene="hpt"
                     /locus_tag="VQ540_001241"
     CDS             complement(2134..2676)
                     /gene="hpt"
                     /locus_tag="VQ540_001241"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HET2545049.1"
                     /translation="MLENDIKKVLVSHDEITEAAKKLGAQLTKDYAGKNPILVGILKG
                     SIPFMAELVKHIDTHIEMDFMMVSSYHGGTASSGVINIKQDVTQDIKGRHVLFVEDII
                     DTGQTLKNLRDMFKAREAASVKIATLLDKPEGRVVEIEADYTCFTIPNEFVVGYGLDY
                     KENYRNLPYIGVLKEEVYSN"
     gene            complement(2680..3957)
                     /gene="tilS"
                     /locus_tag="VQ540_001242"
     CDS             complement(2680..3957)
                     /gene="tilS"
                     /locus_tag="VQ540_001242"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HET2545050.1"
                     /translation="MREPDFLNHFLKKGYFKKHAKAVLALSGGLDSMFLFKVLSTYQK
                     ELEIELILAHVNHKQRIESDWEEKELRKLAAEAELPIYISNFSGEFSEARARNFRYDF
                     FQEVMKKTGATALVTAHHADDQVETILMRLIRGTRLRYLSGIKEKQVVGEIEIIRPFL
                     HFQKKDFPSIFHFEDTSNQENHYFRNRIRNSYLPELEKENPRFRDAILGIGNEILDYD
                     LAIAELSNNINVEDLQQLFSYSESTQRVLLQTYLNRFPDLNLTKAQFAEVQQILKSKS
                     QYRHPIKNGYELIKEYQQFQICKISPQADEEEDELVLHYQNQVAYQGYLFSFGLPLEG
                     ESIQQIPVSRETSIHIRHRKTGDVLIQNGHRKKLRRLFIDLKIPMEKRNSALIIEQFG
                     EIVSILGIATNNLSKKTKNDIMNTVLYIEKIDR"
     gene            complement(3954..5222)
                     /locus_tag="VQ540_001243"
     CDS             complement(3954..5222)
                     /locus_tag="VQ540_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A beta-lactamase-related serine hydrolase"
                     /protein_id="HET2545051.1"
                     /translation="MRKFLIILLLPSFLTISKVVSTEKEVVYTSKEIYYLSQSDFGIY
                     FREKLSSPMVYGEVPVYANEDLVVESGKLTPKTSFQITEWRLNKQGIPVFKLSNHQFI
                     AADKRFLYDQSEVTPTIKKAWLESDFKLYNSPYDLKEVKSSLSAYSQVSIDKTMFVEG
                     REFLHIDQAGWVAKESTSEEDNRMSKVQEMLSEKYQKDSFSIYVKQLTTGKEAGINQD
                     EKMYAASVLKLSYLYYTQEKINEGLYQLDTTVKYVSAVNDFPGSYKPEGSGSLPKKED
                     NKEYSLKDLITKVSKESDNVAHNLLGYYISNQSDATFKSKMSAIMGDDWDPKEKLISS
                     KMAGKFMEAIYNQNGFVLESLTKTDFDSQRIAKGVSVKVAHKIGDADEFKHDTGVVYA
                     DSPFILSIFTKNSDYDTISKIAKDVYEVLK"
     gene            complement(5342..5710)
                     /locus_tag="VQ540_001244"
     CDS             complement(5342..5710)
                     /locus_tag="VQ540_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HET2545052.1"
                     /translation="MSKNIVQLNNSFIQNEYQRRRYLMKERQKRNRFMGGVLILIMLL
                     FILPTFNLAQSYQQLLQRRQQLADLQTQYQTLSDEKDKETAFATKLKDEDYAAKYTRA
                     KYYYSKSREKVYTIPDLLQR"
     gene            complement(5703..5969)
                     /locus_tag="VQ540_001245"
     CDS             complement(5703..5969)
                     /locus_tag="VQ540_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HET2545053.1"
                     /translation="MRLDKYLKVSRIIKRRTVAKEVADKGRIKVNGILAKSSTDLKVN
                     DQVEIRFGNKLLLVKVLEMKDSTKKEDAAGMYEIISETRVEENV"
     gene            complement(6027..9536)
                     /gene="mfd"
                     /locus_tag="VQ540_001246"
     CDS             complement(6027..9536)
                     /gene="mfd"
                     /locus_tag="VQ540_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000258090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HET2545054.1"
                     /translation="MVTLLDLFSENDQIKKWHQNLTDKKRQLILGLSTSTKALAIASS
                     LEKEDRIVLLTSTYGEAEGLVSDLISILGEELVYPFLVDDAPMVEFLMSSQEKIISRV
                     EALRFLTDSSKKGILVCNIAASRLILPSPNAFKDSIVKISVGEEYAQHAFIHQLKENG
                     YQKVTQVQTQGEFSLRGDILDIFEISQLEPCRIEFFGDEIDGIRSFEVETQLSKENKT
                     ELTIFPASDMLLREKDYQRGQSALEKQISKTLSPILKSYLEEILSSFHQKQSHADSRK
                     FLSLCYDKTWTVFDYIEKDTPIFFDDYQKLMNQYEVFERELAQYFTEELQNSKAFSDM
                     QYFSDIEQIYKKQSPVTFFSNLQKGLGNLKFDKIYQFNQYPIQEFFNQFSFLKEEIER
                     YKKMDYTIILQSSNSMGSKTLEDMLEEYQIKLDSRDKTSICKESVNLIEGNLRHGFHF
                     VDEKILLITEHEIFQKKLKRRFRRQHVSNAERLKDYNELEKGDYVVHHIHGIGQYLGI
                     ETIEIKGIHRDYVSVQYQNGDQISIPVEQIHLLSKYISSDGKAPKLNKLNDGHFKKAK
                     QKVKNQVEDIADDLIKLYSERSQLKGFAFSADDDDQDAFDDAFPYVETDDQLRSIEEI
                     KRDMQASQPMDRLLVGDVGFGKTEVAMRAAFKAVNDHKQVVILVPTTVLAQQHYTNFK
                     ERFQNFAVNIDVLSRFRSKKEQTATLEKLKNGQVDILIGTHRVLSKDVVFADLGLMII
                     DEEQRFGVKHKETLKELKKQVDVLTLTATPIPRTLHMSMLGIRDLSVIETPPTNRYPV
                     QTYVLEKNDSVIRDAVLREMERGGQVYYLYNKVDTIVQKVSELQELIPEASIGYVHGR
                     MSEVQLENTLLDFIEGQYDILVTTTIIETGVDIPNANTLFIENADHMGLSTLYQLRGR
                     VGRSNRIAYAYLMYRPEKSISEVSEKRLEAIKGFTELGSGFKIAMRDLSIRGAGNLLG
                     KSQSGFIDSVGFELYSQLLEEAIAKRNGNANANTRTKGNAELILQIDAYLPDTYISDQ
                     RHKIEIYKKIRQIDNRVNYEELQEELIDRFGEYPDVVAYLLEIGLVKSYLDKVFVQRV
                     ERKDNKITIQFEKVTQRLFLAQDYFKALSVTNLKAGIAENKGLMELVFDVQNKKDYEI
                     LEGLLIFGESLLEIKEFKEENSI"
     gene            complement(9537..10106)
                     /locus_tag="VQ540_001247"
     CDS             complement(9537..10106)
                     /locus_tag="VQ540_001247"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HET2545055.1"
                     /translation="MTKLLVGLGNPGDKYFETKHNVGFMLIDQLAKKQNVTFTHDKIF
                     QADLASFFLNGEKIYLVKPTTFMNESGKAVHALLTYYGLDIDDLLIIYDDLDMEVGKI
                     RLRAKGSAGGHNGIKSIIQHIGTQVFNRVKIGIGRPKNGMSVVHHVLSKFDRDDYIGI
                     LQSVDKVDDSVKYYLQEKNFEKTMQRYNG"
     gene            complement(10177..11292)
                     /gene="ychF"
                     /locus_tag="VQ540_001248"
     CDS             complement(10177..11292)
                     /gene="ychF"
                     /locus_tag="VQ540_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HET2545056.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDERLQKLTEMITPKKTVPTTFEFTDIAGIVKGASKGEGLGNKFLANIREVDAIVH
                     VVRAFDDENVMREQGREDAFVDPLADIDTINLELILADLESVNKRYARVEKMARTQKD
                     KESVAEFNVLQKIKPVLEDGKSARTIEFTDEEQKVVKGLFLLTTKPVLYVANVDEDVV
                     SEPDSIDYVKQIREFAATENAEVVVISARAEEEISELDDEDKKEFLEAIGLTESGVDK
                     LTRAAYHLLGLGTYFTAGEKEVRAWTFKRGMKAPQAAGIIHSDFEKGFIRAVTMSYED
                     LVKYGSEKAVKEAGRLREEGKEYIVQDGDIIEFRFNV"
     gene            complement(11376..11570)
                     /locus_tag="VQ540_001249"
     CDS             complement(11376..11570)
                     /locus_tag="VQ540_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 family protein"
                     /protein_id="HET2545057.1"
                     /translation="MYQVGNFVEMKKSHACTIKSTGKKANRWEITRVGADIKIKCSNC
                     EHVVMMGRYDFERKMNKIID"
     gene            complement(11635..12771)
                     /gene="dnaN"
                     /locus_tag="VQ540_001250"
     CDS             complement(11635..12771)
                     /gene="dnaN"
                     /locus_tag="VQ540_001250"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HET2545058.1"
                     /translation="MIHFSINKNLFLQALNTTKRAISSKNAIPILSTVKIDVTNEGIT
                     LIGSNGQISIENFISQKNEDAGLLITSLGSILLEASFFINVVSSLPDVTLDFKEIEQN
                     QIVLTSGKSEITLKGKDSEQYPRIQEISASTPLILETKLLKKIINETAFAASTQESRP
                     ILTGVHFVLSQHKELKTVATDSHRLSQKKLTLEKNSDDFDVVIPSRSLREFSAVFTDD
                     IETVEIFFANNQILFRSENISFYTRLLEGNYPDTDRLIPTDFNTTITFNVVNLRQSME
                     RARLLSSATQNGTVKLEIKDGVVSAHVHSPEVGKVNEEIDTDQVTGEDLTISFNPTYL
                     IDSLKALNSEKVTISFISAVRPFTLVPADTDEDFMQLITPVRTN"
     gene            complement(12921..14282)
                     /gene="dnaA"
                     /locus_tag="VQ540_001251"
     CDS             complement(12921..14282)
                     /gene="dnaA"
                     /locus_tag="VQ540_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HET2545059.1"
                     /translation="MKEKQFWNRILEFAQERLTRSMYDFYAIQAELIKVEENVATIFL
                     PRSEMEMVWEKQLKDIIVVAGFEIYDAEITPHYIFTKPQDTTSSQVEEATNLTLYNYS
                     PKLVSIPYSDTGLKEKYTFDNFIQGDGNVWAVSAALAVSEDLALTYNPLFIYGGPGLG
                     KTHLLNAIGNEILKNIPNARVKYIPAESFINDFLDHLRLGEMEKFKKTYRSLDLLLID
                     DIQSLSGKKVATQEEFFNTFNALHDKQKQIVLTSDRSPKHLEGLEERLVTRFSWGLTQ
                     TITPPDFETRIAILQSKTEHLGYNFQSDTLEYLAGQFDSNVRDLEGAINDITLIARVK
                     KIKDITIDIAAEAIRARKQDVSQMLVIPIDKIQTEVGNFYGVSIKEMKGSRRLQNIVL
                     ARQVAMYLSRELTDNSLPKIGKEFGGKDHTTVIHAHAKIKSLIDQDDNLRLEIESIKK
                     KIK"
     gene            complement(14495..15253)
                     /locus_tag="VQ540_001252"
     CDS             complement(14495..15253)
                     /locus_tag="VQ540_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000410347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HET2545060.1"
                     /translation="MEKFEMISITDIQKNPYQPRKEFDREKLDELAQSIKENGVIQPI
                     IVRQSPVIGYEILAGERRYRASLLAGLRSIPAVVKQISDQEMMVQSIIENLQRENLNP
                     IEEARAYESLVEKGFTHAEIADKMGKSRPYISNSIRLLSLPEQILSEVENGKLSQAHA
                     RSLVGLNKEQQDYFFQRIIEEDISVRKLEALLTEKKQKKQQKTNHFIQNEEKQLRKLL
                     GLDVEIKLSKKDSGKIIISFSNQEEYSRIINSLK"
     gene            complement(15311..16492)
                     /locus_tag="VQ540_001253"
     CDS             complement(15311..16492)
                     /locus_tag="VQ540_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine protease"
                     /protein_id="HET2545061.1"
                     /translation="MKHLKTFYKKWFQLLVVIVISFFSGALGSFSITQLTQKSSVNNS
                     NNNSTITQTAYKNENSTTQAVNKVKDAVVSVITYSANRQNSVFGNDDTDTDSQRISSE
                     GSGVIYKKNDKEAYIVTNNHVINGASKVDIRLSDGTKVPGEIVGADTFSDIAVVKISS
                     EKVTTVAEFGDSSKLTVGETAIAIGSPLGSEYANTVTQGIVSSLNRNVSLKSEDGQAI
                     STKAIQTDTAINPGNSGGPLINIQGQVIGITSSKIATNGGTSVEGLGFAIPANDAINI
                     IEQLEKNGKVTRPALGIQMVNLSNVSTSDIRRLNIPSNVTSGVVVRSVQSNMPANGHL
                     EKYDVITKVDDKEIASSTDLQSALYNHSIGDTIKITYYRNGKEETTSIKLNKSSGDLE
                     S"
     gene            16675..17154
                     /gene="rlmH"
                     /locus_tag="VQ540_001254"
     CDS             16675..17154
                     /gene="rlmH"
                     /locus_tag="VQ540_001254"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000695929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HET2545062.1"
                     /translation="MKIKVVTVGKLKEKYLKDGIAEYSKRISRFAKFEMIELSDEKTP
                     DKASESENQKILEIEGQRILSKIADRDFVIVLAIEGKTFFSEEFSKQLEETSIKGFST
                     LTFIIGGSLGLSSSVKNRANLSVSFGRLTLPHQLMRLVLVEQIYRAFTIQQGFPYHK"
     gene            17198..17271
                     /locus_tag="VQ540_001255"
     tRNA            17198..17271
                     /locus_tag="VQ540_001255"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:17232..17234,aa:Arg,seq:tct)
     gene            17436..17561
                     /gene="comC"
                     /locus_tag="VQ540_001256"
     CDS             17436..17561
                     /gene="comC"
                     /locus_tag="VQ540_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence-stimulating peptide ComC"
                     /protein_id="HET2545063.1"
                     /translation="MKNTVKLEQFVALKEKDLQKIKGGEMRLSKFFRDFILQRKK"
     gene            17582..18907
                     /locus_tag="VQ540_001257"
     CDS             17582..18907
                     /locus_tag="VQ540_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000362880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET2545064.1"
                     /translation="MDLFGFGTVIVHFLIISHSYHFICKGQINRKELFVFGAYTLLTE
                     IVFDFPLYILYLDGLGIERFLFPLGLYSYFRWMKQYERDRGLFLSLLLSLLYESTHNF
                     LSVTFSSITGDNFVLQYHFPFFFVVTVLTYFVTLKIIYYFHLELAYFDEDYLYPFLKK
                     VFFALLLLHIVSFVSDMVSTIKHLNSFGSILSSIVFISLLLTFFAMNSHKVQMEKEIA
                     LKQKKFEQKHLQNYTDEIVGLYNEIRGFRHDYAGMLVSMQMAIDSGNLQEIDRIYNEV
                     LVKANHKLRSDKYTYFDLNNIEDSALRSLVAQSIVYARNNGVEFTLEVKDTITKLPIE
                     LLDLVRIMSVLLNNAVEGSADSYKKQMEVAVIKMETETVIVIQNSCKMTMTPSGDLFA
                     LGFSTKGRNRGVGLNNVKELLDKYNNIILETEMEGSTFRQIIRFKREFE"
     gene            18904..19656
                     /locus_tag="VQ540_001258"
     CDS             18904..19656
                     /locus_tag="VQ540_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000866085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET2545065.1"
                     /translation="MKVLILEDVIEHQVRLERILDEISKESNIPISYKTTGKVREFEE
                     YIENDEVNQLYFLDIDIHGIEKKGFEVAQLIRHYNPYAIIVFITSRSEFATLTYKYQV
                     SALDFVDKDINDEMFKKRIEQNIFYTKSMLLENEDVVDYFDYNYKGNDLKIPYHDILY
                     IETTGVSHKLRIIGKNFAKEFYGTMTDIQEKDKHTQRFYSPHKSFLVNIGNIREIDRK
                     NLEIVFYEDHRCPISRLKIRKLKDILEKKSQK"
     gene            19708..19779
                     /locus_tag="VQ540_001259"
     tRNA            19708..19779
                     /locus_tag="VQ540_001259"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:19741..19743,aa:Glu,seq:ttc)
     gene            19785..19858
                     /locus_tag="VQ540_001260"
     tRNA            19785..19858
                     /locus_tag="VQ540_001260"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:19819..19821,aa:Asn,seq:gtt)
     gene            complement(19899..20441)
                     /locus_tag="VQ540_001261"
     CDS             complement(19899..20441)
                     /locus_tag="VQ540_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator
                     C-terminal domain-containing protein"
                     /protein_id="HET2545066.1"
                     /translation="MQESNKRLKTKRTIENAMVQLLMEQPFDKISTVKLVEKAGISRS
                     SFYTHYKDKYDMIEHYQSKLFHTFEYIFQKHAHHKRDAILEVFEYLESEPLLAALLSE
                     NGTKEIQNFLRNKLHIMLSTDLQKRFMQLNLNTTELEYSSIYLTHALFGVCQTWIAHG
                     KKESSQEITDFLMKMLGDTN"
     gene            20620..21387
                     /locus_tag="VQ540_001262"
     CDS             20620..21387
                     /locus_tag="VQ540_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
                     /protein_id="HET2545067.1"
                     /translation="MIGISLIPDLYNIIFLSSMWDPYGQLSDLPVAVVNNDKEASYNG
                     NTMAIGKDMVSNLKENKTLDFHFVDEEEGKKGLEDGDYYMVVTLPSDLSEKTTTLSNI
                     QSTAAYQSLTSEQQTEISDSVSQNSTDSIQSAQSIVALVQDLQGSLENLQNQSSNLST
                     LKNQSNQVSPITSTSLIGLSSGLTEIQGDVTSKLVPASQSIASGVNAYTTGVDKVSQG
                     ASQLSEKNATLTGSLDKLVSGSNTLTQKSSRLTAGVG"
     gene            21472..22152
                     /locus_tag="VQ540_001263"
     CDS             21472..22152
                     /locus_tag="VQ540_001263"
                     /inference="COORDINATES: protein motif:HMM:TIGR03057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip family protein"
                     /protein_id="HET2545068.1"
                     /translation="MADGSGKLAEGGTKLTSGLEDLQTGLASLGQGLGNASDQLKSVS
                     TESKNAEILSNPLNLSKTDNDQVPVNGIAIAPYMISVALFVAAISTNMIFAKLPSGRH
                     PESRWAWLKSRAEINGIIAVLAGILVYGGVQLIGLTANHEMRIFILIILTSLVFMSMV
                     TTLTTWNSRIGAFFLLILLLLQLASSAGTYPLALTNDFFRSINPWLPMSYSVSGLRQT
                     ISINKSFS"
BASE COUNT         6886 a         4110 c         3640 g         7651 t
ORIGIN      
        1 acagtccctt ggacttcttc atacaattct ttaatcataa ttttcccctt tctagataca
       61 gtctaacaga ttagaaaaca catttgttcc attttctcca ttctgttccc tttagctcct
      121 aaactgcaca aaaaagagag gctccagcct ctctcagggt tatttttcgt cattcatttt
      181 tgactttact tcatcatagg atagtgcatg agattcctct tctactgctt caggcatctt
      241 tcctgtttcg taaagagctt taatttgtgt actatccaat gtttcgtatt tcaataatgc
      301 ttctgcaatt aacttgtgaa tttcacgatt tgactgaata atttcagcag ctttatttcg
      361 tgcctcattt aataatgaac gaacctcttc atcaatttca taagctgttt gttctgaaat
      421 tgatttttga ggactctgtg caccaaacat agcatggttt ccttcatatt gtactgggcc
      481 aagtttttca ctcataccgt actctgtaac cattgcacgc gccatttgtg tcgcttgttc
      541 aaagtcgttt gaagctcctg tagtttggac attaaagata atttcttcag ctacacgtcc
      601 acccattaag ccagccaatt gctctttcat atcttcttta gatagaagca tttgatcctc
      661 tttaggaagt gcaatcatgt atccgcctgc acggccgcgt ggtacaattg taaccttatg
      721 gacaacgcga gcattcgaca agactagacc aacaatggta tgtcctgcct catggtaagc
      781 aaccaattct cgttcttttt gtgaaactgt cttatctttc ttagaaggtc cagcaataac
      841 tctatcttct gcttcatcaa tatctgaagc atcaattatc gatttattgc gacgagcagc
      901 aactaaagct gcttcattca agacattctc taaatcagca ccaacaaagc ctggagtttg
      961 ttgagccact aatttcaaat caacatcttc tgctaaaggc ttgttcttag cgtgaacttt
     1021 caagattgct tcacgacctt taacatcagg acgaccaacc aatacttttc tatcaaaacg
     1081 tcctggacgc aaaagggcag gatcaagtac atctgaacgg tttgtcgcag cgatgacgat
     1141 aatcccttca tttccctcaa aaccatccat ctcaatcaaa agttggttca aggtttgttc
     1201 acgttcgtca ttacctccgc cgagaccgac tccacgttga cgtccaacag catcaatttc
     1261 atcgataaag atgatagctg gtgctgcttt tttggcatcc tcaaaaagag agcgaacacg
     1321 actagctcca actccgacaa acatttctac aaagtcagaa cctgagatac taaagaatgg
     1381 aacacctgct tctccagcga ctgccttagc aagcaaagtt ttacctgtcc ccggaggtcc
     1441 ctccaaaaga acacctgctg gaatacgggc tccaagtttt gtgaatcgtt ttggatcttt
     1501 taagaactca acaacttcaa ctagttcttg tttttcttcc tcagctccag caacatctga
     1561 aaatcttact ttaatatctt ctttatttgc tgctttagcc ttactacgtc caaaactcat
     1621 tggattacgg ccattgcctc ctcccatatt tcccatcata gagaatagga agaagaatag
     1681 aattccaaat ggcacaatgg atacgagtag attaatccat ataccacttg aactttcatg
     1741 cttaacagtt acttctgctt tatggtcagt agcaagtttt tgcaattctg atacggtagt
     1801 atctgcagga agaatagtgc tggtaaattt ctctacctta gtaacagatg gcgtgaaaaa
     1861 ctgaatacct gtttcttctt tacttgtttt aggattttta tagacaccag aaacttcgat
     1921 aacactacca tttggttggt aagttaattc ttttacatta ccatcggtaa tttcttgtac
     1981 caactcagta tagttgattt gctgacttcc tcctgagtta ttcccagaat agaaatactg
     2041 gaatcctgtc acaaggaaaa agataaataa taaccataga aaaggatttt taattaaacc
     2101 attattttgt tttttcatta aagattattc tttctaattt gaatacactt cctctttcaa
     2161 tactccaata taaggaagat tacgataatt ttctttgtag tctaaaccat aacctactac
     2221 aaactcattt gggatagtaa agcaggtata gtctgcctca atttctacaa cacgtccttc
     2281 tggtttatcc aacaaggttg caattttaac agaagctgct tctcttgctt taaacatatc
     2341 tcgcaaattc ttcaaagttt gacctgtatc aatgatatct tctacaaata gaacatgtct
     2401 tcctttgata tcttgagtca catcttgttt aatattgata acaccactac ttgctgttcc
     2461 accatggtag ctagaaacca tcatgaagtc catttcaata tgtgtatcaa tatgtttgac
     2521 caattcagcc ataaaaggaa tagatccttt taaaatccca actaagattg gattttttcc
     2581 tgcatagtct ttagttaatt gagcacctag ttttttagct gcttctgtaa tttcatcgtg
     2641 tgaaacgagg acttttttaa tatcgttttc taacattttt tacctatcta ttttttctat
     2701 ataaagtaca gtgttcatta tatcattttt cgttttttta ctcaaattat tggtcgcaat
     2761 tcccaaaatt gagacaattt caccaaattg ctcaataata agagcagagt ttctcttttc
     2821 catagggatt ttcaaatcaa taaataaacg tctgagtttt tttctatgcc cattttgaat
     2881 caaaacatct cctgtttttc gatgacgaat gtgtatggat gtttcacgtg aaacaggtat
     2941 ttgttgaatt gattcacctt ctaatggaag tccaaaggaa aataaatatc cttgataagc
     3001 tacctgattt tgatagtgta acacaagttc atcttcctct tcatcagcct gcggactgat
     3061 tttacaaatc tgaaactgtt ggtactcttt tatcaattca tagccatttt taatcggatg
     3121 acgatactgg cttttagatt ttaaaatctg ctgaacttca gcaaactgag cttttgtaag
     3181 attcaaatct ggaaaacgat tcagataagt ttgaagtaaa actctttgtg tagactcaga
     3241 gtaagaaaat aactgctgta aatcttccac attaatattg ttagataatt cagctattgc
     3301 caaatcataa tctaaaattt cattgccaat gcctaagatt gcatccctaa atcgaggatt
     3361 ttctttttcc aattctggta agtaagagtt tcgaatacga tttcgaaaat aatgattctc
     3421 ctgatttgat gtatcttcaa agtgaaaaat tgatggaaag tcttttttct gaaaatgcaa
     3481 gaagggacga atgatttcta tctctccgac tacttgcttc tccttaattc ctgatagata
     3541 gcgcaagcga gttcctcgaa tcaagcgcat caaaatcgtt tccacctgat catcagcatg
     3601 gtgggcagtg actaaagctg tcgcacctgt ctttttcatg acctcttgaa aaaaatcata
     3661 acgaaaattt cgtgcacgcg cttctgaaaa ttctcctgaa aaattgctga tataaatagg
     3721 aagctctgct tcagcagcca acttccttaa ttccttttct tcccaatctg attcaattct
     3781 ctgcttatga ttcacatgag ctagaatcaa ttcaatctct aactcttttt gataagtaga
     3841 caatacctta aatagaaaca tggaatctaa tccaccagaa agagctagaa ccgccttagc
     3901 atgctttttg aaatatccct tcttgagaaa atgatttaaa aaatctggtt ccctcatttt
     3961 agaacctcat aaacatcctt ggctatctta gaaatcgtat cataatcaga attcttagtg
     4021 aaaatagaaa gaataaatgg agaatctgca tagacaacac ccgtatcatg cttaaattca
     4081 tccgcatctc caattttatg agctacttta acagaaacac ctttggcaat tcgctgacta
     4141 tcaaaatctg ttttagtcaa agactctaac acaaatccat tttgattata aatagcttcc
     4201 ataaacttcc cggccatctt agaagaaatc aatttttctt ttggatccca atcatctccc
     4261 ataatggcag acatcttgga tttgaatgtg gcatcagatt ggtttgaaat gtaatatccc
     4321 aatagattat gagctacatt atcagattct tttgatactt tcgtaattaa atcctttaaa
     4381 gaatattctt tattatcttc ttttttagga agactaccac ttccctctgg tttataagaa
     4441 cctggaaaat cattgactgc agatacgtat tttacagtcg tatctaactg ataaagaccc
     4501 tcatttattt tttcttgcgt ataatagaga taagagagtt tcaaaacgct ggctgcatac
     4561 atcttttcat cttgattgat accagcttct tttccagtag tcagttgctt aacataaata
     4621 gagaaagaat ctttctgata tttttcagat aacatttctt gaactttact catccgatta
     4681 tcttcttcag aagttgattc tttagctacc catccagcct gatcaatatg tagaaattct
     4741 cttccttcta caaacatggt cttgtcgatt gatacttgcg aataagctga taaggatgat
     4801 ttcacttctt ttaaatcata aggactattg tacagtttaa agtcagattc taaccatgct
     4861 ttttttattg ttggagttac ctctgattga tcatataaaa atcgtttgtc cgcagctata
     4921 aattgatgat ttgatagctt aaatactgga attccttgtt tatttaagcg ccactcggtt
     4981 atttgaaaac ttgttttggg agtcaatttc ccagattcca ctactaaatc ttcattcgca
     5041 taaacaggaa cctctccata aaccatggga gaacttaatt tttctctaaa ataaatacca
     5101 aagtcagatt gtgaaaggta ataaatttct ttcgaagtat agacgacttc tttttctgtg
     5161 ctaacgactt ttgaaatggt caaaaaactt ggtagcaaca aaataattaa gaatttacgc
     5221 attcttcctt tccttttctt cttgtaaacg caataattga tttttatcag ccaattcttc
     5281 cagcttttca tctgacaaac tcaaaaattg ctctattacg tctaataaat tttccatttt
     5341 atcacctttg aagcaagtca ggaatcgtat aaactttttc cctcgactta gaataatagt
     5401 acttcgctcg tgtatatttg gcagcataat cttcatcttt caacttggta gcaaatgctg
     5461 tctccttatc cttttcatca ctcaaagttt gatactgagt ttgcaagtct gctaattgct
     5521 gacgtctttg gagtaattgc tgataactct gcgctaaatt aaaagttggc aagataaata
     5581 atagcataat caaaatcaat acccctccca taaaacgatt ccgtttttgt cgttctttca
     5641 tcaggtagcg acgacgttgg tattcatttt gaataaaaga attattcaat tgtacaatat
     5701 ttttagacat tttcttctac ccgtgtttca ctgataattt catacattcc tgctgcatct
     5761 tctttttttg tactatcttt catctctagt acttttacaa gcagcaactt attgccaaag
     5821 cgaatttcaa cttggtcatt aactttcaag tccgttgaac ttttggccaa gattccatta
     5881 accttgattc tacctttatc tgctacttcc tttgcgactg tacgacgctt gataattcgc
     5941 gatactttta aatatttatc taatctcatc cttattacct caatttatta ttgtaccatt
     6001 tttatctatt ttatagaaga aaaatatcaa atggaatttt cttccttaaa ctcttttatc
     6061 tctaataaac tttctccaaa aatcagcaga ccttctaaaa tttcataatc tttcttattt
     6121 tggacatcaa atacaagctc cattaatccc ttattctcag cgatgcctgc ttttaagttc
     6181 gttacggata aagctttaaa ataatcttga gctaaaaaca atcgttgagt gactttttca
     6241 aattgaattg taattttatt atcttttctt tccacacgtt gaacaaagac cttgtccaag
     6301 tatgatttaa ccaaaccaat ctctaaaaga taggctacta catctgggta ttctccaaaa
     6361 cggtctatca actcctcttg taactcttca taattgacac ggttgtcaat ttgacgaatt
     6421 ttcttgtaaa tttcaatctt atgtcgttga tcagaaatat aagtatcagg aagataggca
     6481 tcaatttgca aaatcaactc agcattccct ttggttcttg tgttagcgtt agcattaccg
     6541 tttcgtttag caatagcttc ctctaataac tgcgaataca attcaaaacc aacagaatca
     6601 atgaaaccag actgggattt tcctaaaaga tttcctgctc cacgaatcga aagatctcgc
     6661 attgcaatct taaagccaga gcccaattct gtaaatcctt taatcgcttc taatctcttt
     6721 tcagagactt cactgattga tttttctgga cgatacatga gataagcata agcaatacga
     6781 ttactacgac cgactcttcc tcttaactga tataaggttg acaagcccat atggtccgca
     6841 ttttcaataa ataaagtatt agcatttgga atgtccaccc ctgtctcaat aatagtagtc
     6901 gtcaccaaga tatcgtattg tccctcaata aagtctaata gagtattttc caactggact
     6961 tcactcattc gaccatgaac atatccaatc gaagcctccg gaatcaactc ctgtaattct
     7021 gaaaccttct gaacaattgt gtcaactttg ttgtaaagat aataaacttg acctccacgc
     7081 tccatttcac gcaagacagc atcacgaatg acactatcat tcttttccaa aacataggtc
     7141 tgaacaggat agcgattagt cggcggagtt tcaataacag ataaatctct gattcccagc
     7201 atagacatat ggagggtacg agggattggc gtagcggtca aggttaggac atccacttgt
     7261 ttcttcagtt ctttcaaagt ttccttatgc ttgacaccaa atcgctgttc ctcatcaata
     7321 atcatcaagc ccaaatcagc aaacacaaca tcttttgaca aaacacgatg tgttccaatc
     7381 aaaatatcga cttgaccgtt tttcaatttt tcaagtgttg cagtctgctc ttttttactt
     7441 ctaaagcgac tcaacacatc aatattaact gcaaaatttt ggaatcgttc cttaaaattc
     7501 gtatagtgct gttgcgctaa aaccgtcgtc ggaactagaa tgacaacctg tttgtgatca
     7561 ttgactgctt taaaggctgc acgcatagca acttcagtct ttccaaaacc aacatcccca
     7621 actaaaagtc gatccattgg ctgagaagcc tgcatatccc tcttgatttc ctcaatacta
     7681 cgaagttgat catccgtttc aacataaggg aaagcatcat caaaggcatc ttgatcatca
     7741 tcatcagctg agaaagcaaa acccttcaac tgactacgtt cagagtagag tttgattaaa
     7801 tcatcagcta tatcctctac ctggttctta accttttgct tggccttttt aaaatgaccg
     7861 tcatttaatt tattgagttt tggagcttta ccatcacttg aaatatattt ggacagtaga
     7921 tgaatctgtt ccacggggat agaaatttga tcaccatttt ggtattggac actgacataa
     7981 tcgcgatgaa ttcccttgat ttcaatggtt tcaattccta gatattgacc aatcccatgg
     8041 atatgatgga caacatagtc ccctttttca agttcattgt aatcttttaa tctctctgca
     8101 tttgaaacat gttgtcttcg aaaacgacgc tttaatttct tttgaaaaat ctcatgttca
     8161 gttatcaata aaatcttttc atctacaaaa tgaaaaccat gtctgagatt accctctatt
     8221 aaatttacag attctttaca gatacttgtc ttatctctag aatccaattt aatctgatat
     8281 tcctctaaca tatcctccaa tgttttactt cccattgaat tgctagactg cagaataatg
     8341 gtgtaatcca tttttttata tcgttcaatt tcttctttta gaaaagaaaa ctgattgaaa
     8401 aattcctgta taggatattg attgaattga taaattttgt caaatttgag atttcctaaa
     8461 cccttttgaa gattagagaa aaaggtcact ggactttgtt ttttatagat ttgttcaata
     8521 tcagaaaaat actgcatatc agaaaatgct ttactattct gtaattcttc tgtaaagtac
     8581 tgcgctaatt ctctttcaaa gacttcatac tgattcatca atttttgata atcatcaaag
     8641 aatattggag tatctttttc aatataatca aagacagtcc atgtcttatc atagcacaaa
     8701 gataaaaact tccgagaatc tgcatgactt tgtttttggt gaaaacttga aagaatttct
     8761 tctaggtatg atttcaaaat aggtgataaa gtttttgaaa tttgtttttc taaagctgac
     8821 tgtcctcgtt gataatcctt ttctctcaaa agcatatcac tagctggaaa gatagtgagt
     8881 tctgtcttat tttctttcga taattgtgtt tctacttcaa atgacctgat accatcaatt
     8941 tcatcaccaa aaaactcaat tcgacaaggt tctaactggg atatttcaaa aatatctaaa
     9001 atatctcctc gaagactaaa ttcgccctga gtttgtactt gagtaacttt ttgatagcca
     9061 ttttccttta actgatggat aaacgcgtgt tgagcatatt cttcaccaac tgagattttt
     9121 acaatactat ctttgaatgc attgggagac ggtaaaatca atcgacttgc tgcgatatta
     9181 caaactaaaa tccctttctt agatgaatca gtcaaaaaac gcaaggcttc aacccgtgaa
     9241 ataatttttt cctgtgaaga catcaaaaac tccaccatag gagcatcatc taccaaaaat
     9301 ggatagacga gttcctcacc caagatagaa ataagatcac taacaagtcc ttctgcttct
     9361 ccataagttg acgtcaataa cacaatccta tcttcttttt ctaaactgct tgcaattgca
     9421 agagccttag tagatgttga taaaccaagt attagttgtc ttttcttatc tgttaaattt
     9481 tgatgccatt ttttaatctg atcattttct gagaataaat ctaataaggt caccatttat
     9541 ccgttatacc tctgcattgt tttctcaaaa tttttctctt gtaaatagta ttttacagaa
     9601 tcgtcaactt tgtcaacaga ctgtaaaata ccgatataat catccctgtc aaacttactc
     9661 aaaacatgat gaacaactga cataccattt ttaggtcttc caattccaat cttaacacgg
     9721 ttaaagacct gagttcctat atgttgaata atagacttga taccattatg accacctgct
     9781 gagccttttg ctcttaaacg aattttccca acttccatgt caagatcatc gtaaatgata
     9841 agtaaatcgt caatatccaa accatagtaa gttaataaag catgaactgc ttttccactt
     9901 tcattcataa aggtcgttgg tttaaccaga taaatttttt ctccatttag gaaaaaggat
     9961 gctaggtcag cttgaaatat cttatcgtgt gtaaaagtga cattctgttt cttcgctagt
    10021 tgatcaatca acataaaacc aacattgtgt tttgtttcaa aatatttatc ccctggattt
    10081 cccaaaccta caagtaattt ggtcatttat ttttcctttc aaaagccaaa agggttggaa
    10141 tttttttcca acctaattga caccatttat taatttttag acattaaagc ggaattctat
    10201 gatgtcgcca tcttgaacga tatattcttt tccttcttca cgcaagcgtc cagcttcttt
    10261 tacggccttt tcagatccgt atttcactag atcttcatat gacatggtta ctgcacgaat
    10321 aaagcctttt tcaaagtctg agtggataat accagctgct tgaggagcct tcataccacg
    10381 tttgaaagtc caagcgcgaa cttctttttc accagctgtg aagtaagttc ccaatccaag
    10441 caagtggtaa gctgcacgcg tcaacttatc tacacctgat tctgtcaaac caatggcttc
    10501 aagaaactct tttttatctt catcatccaa ttcagaaatt tcttcctcag cacgcgcaga
    10561 aataacgact acttcagcat tttctgtcgc tgcaaattca cgaatttgtt tgacatagtc
    10621 gatagagtca ggttctgaaa ccacatcctc gtccacatta gctacataaa gaactggttt
    10681 agtcgtcaaa aggaaaagac ctttgacaac cttttgttcc tcatctgtaa attcaatggt
    10741 acgagctgat ttcccgtctt ctaggactgg tttaatcttt tgaagaacat tgaattctgc
    10801 tactgattct ttatcttttt gcgtacgtgc catcttttct acacgcgcat atcgtttgtt
    10861 cactgattct aagtcagcaa gaattaattc cagattaatt gtatcaatat ctgcaagtgg
    10921 atctacaaag gcgtcttcac gtccttgctc gcgcatcaca ttttcatcat caaaagcacg
    10981 aactacgtga acaatcgcat ctacttcacg aatattggcc aagaatttat tccctagccc
    11041 ttctcctttt gaagctcctt ttacaatccc tgcaatatcc gtaaattcaa atgttgtggg
    11101 aactgtcttt ttaggagtta tcatttcagt tagtttttgt aggcgttcat ctggaacttc
    11161 caccattcca acatttggat caatcgtcgc aaatgggtag tttgctgcct ctgctcctgc
    11221 ttttgtaatt gcattaaata gtgttgattt accaacgttt ggcaaaccaa cgatacctgc
    11281 tgtcaaagcc atatttctca ttctccgttt tcatttcaat ccctaatatt ataacacaaa
    11341 aagggataaa gtgctaaccc tctaactaag ggttctcagt caataatttt attcattttt
    11401 cgctcaaaat catatcgccc catcatgaca acatgctcac aattactgca ttttattttg
    11461 atatctgctc ctacacgtgt aatttcccaa cgattagcct ttttaccagt cgacttgatt
    11521 gtacaagcgt gtgatttttt catctcaaca aaatttccaa cttgatacat actactctcc
    11581 ttttcttttt cgattatatc ataaaagagg cgagccaggc tcaacctctt tcacttaatt
    11641 tgtacgaact ggtgtaatga gctgcatgaa gtcttcgtca gtatctgctg gcacaagagt
    11701 aaatggacga acagctgaga taaagctaat ggtcaccttt tcgctattta aagctttaag
    11761 agaatcaatc aagtaagttg ggttgaaact aatggtcaaa tcttcaccag taacctgatc
    11821 agtatcgatt tcttcgttta ctttaccaac ttctggagag tgaacatggg cgctaacaac
    11881 cccatcctta atttcaagtt tcacagtacc attttgagtc gcacttgata aaagacgggc
    11941 acgctccatt gactggcgta agtttaccac attaaaagta atagtagtgt taaagtctgt
    12001 tggaatcaag cgatctgtat caggatagtt tccttctagg agacgagtat agaagctaat
    12061 attttcgctt ctaaagagga tttggttatt ggcaaagaaa atctctacag tttcgatatc
    12121 atctgtaaat accgctgaaa attcgcgtag agaacggcta ggaattacga catcaaaatc
    12181 atcactattt ttttcaagag tcaatttttt ctggcttagg cgatgagagt ctgttgcaac
    12241 tgtttttaac tctttgtgtt gactcaatac gaagtggaca cctgttaaaa tcggacgact
    12301 ctcttgtgta cttgcagcaa aggctgtttc attaataatt ttcttgagta attttgtttc
    12361 aagtattaaa ggagtgcttg ctgaaatttc ttggattcgt ggatattgtt cgctatcttt
    12421 tccttttagg gtaatttctg atttgccact ggttaaaaca atttgatttt gttcaatttc
    12481 tttaaaatca agagttacat caggtaaact agatactaca ttgataaaga aagaagcttc
    12541 aagaaggatc gaacctaaag aagtaattaa caaaccagca tcttcatttt tttgagaaat
    12601 aaaattttca attgaaattt gaccatttga accaattaaa gtaatacctt cattggtcac
    12661 gtcaattttt actgttgata aaataggaat ggcattttta gaactaatag ctctcttagt
    12721 agtatttaat gcttgtagaa ataaattttt attaattgaa aaatgaatca tggattctcc
    12781 tttatttatt tttagtatta gaaagataat agtaataata gagtctgtga aatctgtgga
    12841 taacagcctt taaacaagtc atatcaagtt ttttagcttg tttaaaaaat gtggataaaa
    12901 aactaaaagt tatccacaaa ttatttgatt ttctttttga ttgattcaat ttctaaacgt
    12961 aaattatcgt cttgatcaat caaagatttt attttggcat gggcatgaat gactgtggta
    13021 tgatcttttc ccccaaattc cttcccaatt tttggaagac tattatctgt tagttctcta
    13081 gataaataca tggctacttg acgggccaaa acaatatttt gaaggcgtct acttcccttc
    13141 atttctttga tactaacacc ataaaagtta ccaacttcag tttggatttt atcaattggg
    13201 atgacgagca tttggctaac atcttgtttg cgggctctaa tggcttctgc agcaatatca
    13261 atagtgatat ccttgatttt ttttactctg gcaattaaag tgatgtcgtt gatggctccc
    13321 tcaagatctc gaacatttga atcaaattgc ccagctaggt attctagagt atcactttgg
    13381 aaattgtagc ctaaatgttc cgttttactt tgtaaaatgg caatacgtgt ttcaaagtca
    13441 gggggtgtga tagtttgtgt caatccccaa ctaaaacgcg tgacaagcct ctcctcgagc
    13501 ccttctagat gttttggact acgatcactc gttaggacaa tctgtttttg cttgtcatga
    13561 agggcgttaa aggtattgaa aaattcttcc tgagttgcga ctttttttcc gctgagtgac
    13621 tggatatcat cgattaacaa aagatcaaga ctacgatagg tctttttaaa cttttccatt
    13681 tccccaagtc ttaggtgatc aagaaagtca ttaataaagc tttcggcagg gatatattta
    13741 acacgcgcat taggaatatt ttttagaatt tcatttccaa tagcgtttaa taagtgagtc
    13801 ttaccaaggc ctggtcctcc atagataaaa agagggttat aggtcagagc caaatcttca
    13861 gagacagcta aagcggctga cacagcccaa acatttccat ccccttgaat aaagttatca
    13921 aaggtatact tttcttttaa tcccgtatct gaataaggaa tagatactaa ctttggacta
    13981 tagttataaa gagttaaatt tgtagcttct tcaacttgtg agctagtcgt atcttgaggt
    14041 ttggtgaaaa tatagtgggg agttatttca gcgtcataaa tttcaaaacc agctactaca
    14101 ataatatctt ttagttgttt ttcccagacc atttccattt cagagcgagg tagaaatata
    14161 gtggcaacat tttcctctac cttgatgagt tcagcttgaa tagcatagaa atcatacatg
    14221 gatcgagtca gtctttcttg tgcaaattct aatatacgat tccaaaattg tttttctttc
    14281 aatcctttct cctcctttac tatttaaaag tttaatacta gagatatttt accatagata
    14341 gcaagaattt tccacaagct gtgaaaaata atccacaatg ttaccaaact ttatccacag
    14401 gttggggata aaagaagaaa ttattgattt attaagcttt ttattgaaaa acatagtgga
    14461 taaccttgtg agataaaaaa ataaaagaac agccttattt caggctgttg ataattctac
    14521 tatattcttc ttgatttgaa aaagaaataa tgatttttcc actgtctttt ttagatagtt
    14581 taatttctac atctaatccg agtagttttc ttaactgttt ttcttcattt tgtatgaaat
    14641 gattagtttt ttgctgtttc ttttgttttt tctctgtcag aagagcttct aatttcctta
    14701 cagaaatatc ttcttctata atccgttgaa agaaatagtc ttgttgttcc ttatttaacc
    14761 caactaggga acgcgcatgg gcttgtgata gtttgccatt ttctacttct gaaagaatct
    14821 gttctggcaa ggaaagtaaa cgaatggagt tgctgatata tggacgagac ttgcccatct
    14881 tatctgcaat ttcagcatgg gtgaatcctt tctctacgag agattcatag gcgcgtgctt
    14941 cttctattgg gtttaaattt tctctctgta aattttcaat aatggactgg accatcatct
    15001 cttggtctga aatctgttta acaacagctg ggatagaccg tagaccagct aaaagtgaag
    15061 cccgatagcg tctctctcct gcaaggattt cataaccaat aacaggagat tgacgaacaa
    15121 taatcggttg aatgacccca ttttctttga tagactgtgc tagttcatct agtttttctc
    15181 tatcaaattc ttttcggggt tgatagggat ttttttgtat atctgtgata gaaatcattt
    15241 caaatttttc catgattcta cactaacaca tcttttctct tatgtaaagc tttctttaca
    15301 tagatgtcaa ttaagattct aaatcacctg aactcttgtt aagtttgata gaggtagttt
    15361 cttctttccc gttacgatag taggttatct taatggtgtc tccgatagaa tggttgtaaa
    15421 gagcactttg taagtctgtt gatgaagcaa tctctttgtc atctactttt gtaattacat
    15481 cgtatttttc aaggtgacca ttggcaggca tattactttg taccgaacga acaactacac
    15541 cagatgtaac attacttgga atattgagtc ttctgatgtc gcttgtactc acattagata
    15601 aattaaccat ctggattccc aaagctggac gcgtcacttt tccgtttttt tctaactgtt
    15661 caataatatt gatagcatca tttgcaggaa ttgcgaaacc aagaccttct acagatgttc
    15721 ctccatttgt agcaatttta cttgaggtaa ttccgataac ctgcccttga atattgatca
    15781 gtgggccgcc agagttacct gggttaatag cagtatcagt ttggatggct tttgtagaaa
    15841 tagcttgtcc atcttccgat tttaaggata catttctatt gagactggat acgatacctt
    15901 gagtgacagt atttgcatat tcagaaccta acgggctacc gatggcaata gcagtttctc
    15961 ctacagttaa cttactagaa tcaccaaact cagctactgt tgtcactttt tctgaagaga
    16021 tttttacgac agcaatatca gagaaagtgt cagctccgac aatttctcca ggtactttag
    16081 tcccatctga caatcgaata tctactttgc tggcgccatt tataacgtga ttgttggtga
    16141 cgatgtaagc ttctttatca ttctttttat aaataactcc agatccttca ctagagattc
    16201 gctgagaatc tgtgtcagta tcatcattgc caaatacgct attttgtctg tttgccgaat
    16261 aagtaataac agaaacaaca gcatctttta ctttgttaac agcctgtgtt gttgaatttt
    16321 cgttcttata ggcagtttgt gtaatagtac tattgttgtt agagttgttt acactacttt
    16381 tttgagttag ttgagttatt gaaaaactac ccaaggctcc actaaaaaag ctaatgacga
    16441 taacgactaa taattgaaac cattttttgt aaaatgtttt tagatgtttc atatttgcct
    16501 ccatatgttt gaattactga aagtataaac tgactagctt aattataact taaacacaaa
    16561 agttttacac aaactgtgga taactctttt gaaactgtga ttttcttaat tgaaatctat
    16621 tttttatttt gtgaataaga tgtgaaaaaa tagagaatat gttagaatag agtcatgaaa
    16681 attaaagttg taacagttgg gaaactgaaa gaaaagtatt taaaagatgg tatcgcagag
    16741 tattcaaaac gaatttctag atttgctaag tttgaaatga ttgagttatc agatgaaaaa
    16801 acaccagata aggccagtga atcagaaaat caaaagattt tagaaataga aggtcagaga
    16861 attttatcaa aaattgctga ccgtgatttc gttattgtgt tagccattga agggaaaact
    16921 ttcttctcag aagaatttag taagcagtta gaagaaactt ctataaaagg attttctact
    16981 cttactttta ttattggggg aagtttagga ttgtcatcat ctgtaaaaaa tagagccaat
    17041 ctttctgtca gttttggtcg cctaacctta ccccatcagt taatgagact agttcttgtt
    17101 gaacaaatct atcgcgcttt tacgattcag cagggattcc cctaccataa atagaaaatt
    17161 gacttttaat tgaatttttg gtagaataat tgtattaggt ctcatagctc agctggatag
    17221 agcattcgcc ttctaagcga acggtcgcag gttcgaatcc tgctgggatc aatataatag
    17281 caaagctggg aattttcccg gcttttttct taaaaaagta cactttggga gaaaaaaatg
    17341 acagttgaga gaattttatc taaaacgaaa ttccattttg tataatggtt tttgtaagtt
    17401 agcttacaag aaaaaacatt ttaggagatt ttattatgaa aaacacagtt aaattggaac
    17461 agtttgtagc tttgaaggaa aaagacttac aaaagattaa aggtggggag atgaggttgt
    17521 caaaattctt ccgtgatttt attttacaaa gaaaaaagta atgaaataag gggaaagagt
    17581 aatggattta tttggatttg ggacggttat tgttcatttt ttaattatta gtcacagtta
    17641 ccattttatt tgtaaaggtc aaataaatag aaaagaatta ttcgtttttg gtgcttatac
    17701 attactaaca gaaatagtat ttgattttcc cttatatatt ctatatttag atgggttagg
    17761 gattgaaaga tttttatttc ctttgggatt atattcctat tttcgatgga tgaaacagta
    17821 tgagagggat agaggactat tcctaagttt actactatct cttttatatg agagcactca
    17881 taactttctg tccgtaactt tctcctctat aacaggagat aattttgttt tacaatatca
    17941 tttcccattc tttttcgttg tgacggtgtt aacctatttt gttacattaa aaatcattta
    18001 ctatttccat ttggaactag cctattttga cgaggactac ctttatcctt tcttgaaaaa
    18061 agtatttttt gctttactat tgctacatat tgtatctttc gtttcagata tggtaagtac
    18121 gattaaacat ttgaatagtt ttggaagtat tttgtcatct attgtcttta tctctctcct
    18181 tttgaccttc tttgcaatga attctcataa agttcaaatg gagaaagaga ttgctttgaa
    18241 gcagaagaaa tttgaacaga aacatttaca gaattacaca gatgaaattg ttggtctgta
    18301 taatgaaatc cgtggttttc gacatgatta tgctggaatg cttgtcagca tgcagatggc
    18361 aattgacagt ggtaatttac aggaaattga cagaatttac aatgaagttt tagtcaaagc
    18421 aaatcataaa ttgcgttcag ataagtacac ttactttgat ttgaacaaca tagaagactc
    18481 agctttacga agtttggttg ctcagtcaat tgtctatgct cgaaataatg gtgtagagtt
    18541 tacactggaa gtaaaagata cgattaccaa gcttccaatt gaactattgg atttggttcg
    18601 tatcatgagc gttttattga ataatgctgt cgaaggatcg gctgatagct ataaaaagca
    18661 gatggaagta gcagttatta agatggaaac tgaaacagtt attgtgattc agaattcatg
    18721 taaaatgacg atgactcctt caggagatct atttgcctta ggattctcca ctaagggaag
    18781 aaatcgcgga gtcggattaa ataatgtgaa agaactacta gataagtaca acaatattat
    18841 tttagaaaca gagatggaag gcagtacatt tagacaaatc attagattta agagggaatt
    18901 tgaatgaaag ttttaatttt agaagatgtt attgaacatc aagtgagact agagagaata
    18961 ttggatgaaa tttcgaaaga atcgaatatt ccaatatcat acaagacaac gggaaaagtc
    19021 cgtgaatttg aagaatacat tgaaaatgat gaagtaaatc agctttattt cctagatatc
    19081 gatattcatg gaattgagaa aaagggattt gaagtggctc agctcattcg tcattacaat
    19141 ccttacgcta ttatcgtctt tatcactagt cgatcagagt ttgcgactct aacctataaa
    19201 taccaggtat cagccctaga ttttgttgat aaggatatca atgatgagat gtttaagaag
    19261 agaattgagc aaaatatctt ctacacgaag agtatgttac ttgaaaatga agatgttgta
    19321 gattatttcg actacaatta caagggaaat gatttaaaaa ttccttacca tgatattttg
    19381 tatattgaaa caacaggggt ctctcataaa ttgcgcatta ttggtaagaa ttttgcaaaa
    19441 gagttttatg gtaccatgac agatattcag gaaaaggaca aacatactca gcgattttat
    19501 tctcctcaca agtcattttt ggtaaatata ggcaatatca gagaaattga tcgaaaaaac
    19561 ttagaaattg ttttctatga agaccatcgt tgtcctattt caagattaaa aattagaaaa
    19621 ttaaaagata ttttagagaa aaaatctcaa aagtgattga caattagcaa gaaattgata
    19681 taatggttat atctgctaca gatagaaggt ccgttggtca aggggttaag acaccgcctt
    19741 ttcacggcgg taacacgggt tcgaatcccg tacggactat tttatccgcc atagctcagt
    19801 tggtagtagc gcatgactgt taatcatgat gtcgtaggtt cgagtcctac tggcggagta
    19861 tagataaaag ggaacacagc tgtgttcctc tttttgtatc aatttgtatc accaagcatt
    19921 ttcataagga agtctgttat ttcttgagaa ctttcttttt ttccatgtgc aatccaagtt
    19981 tggcagacac caaaaagtgc atgagttaga tagatgctac tatattctaa ttcggtggta
    20041 tttagattca gttgcataaa tcgcttttgt aaatctgtac taagcatgat atgaagttta
    20101 tttcgtaaga aattttggat ttctttagtc ccattttcag aaagaagggc agccagaagt
    20161 ggttctgact ctagatattc aaaaacttct aaaatagcgt ctcttttgtg atgagcatgt
    20221 ttttgaaaaa tatattcaaa tgtatggaat agcttgcttt gatagtgctc aatcatatca
    20281 tacttatcct tatagtgagt atagaagctg gaacgactaa ttccggcttt ttctactaat
    20341 ttgacagtag aaattttatc aaatggctgt tccatcagta attgtaccat agcattttca
    20401 atagttcgct ttgtttttaa gcgtttgtta ctttcttgca tatttcctcc ttgtaaacaa
    20461 attagactat atgtttaaaa atagattttt tatcttgtaa tttagatttt ttaatgtata
    20521 atctattata tcaaaatttt agacaatatg tttaaaaaag gagaaactaa gtttaaagaa
    20581 tggaaagcaa tttaaaaaaa accaaccttt attattgtca tgatcgggat ttctcttatt
    20641 ccagatctgt acaatatcat atttttgtca tcaatgtggg atccatatgg gcaattgtct
    20701 gacttacctg tggcagttgt aaataatgat aaagaggctt cctataatgg taatactatg
    20761 gcaataggaa aagacatggt gtccaattta aaagaaaata aaaccttgga ttttcatttt
    20821 gtagatgaag aggaaggaaa gaagggattg gaagatggcg attactatat ggtagtgact
    20881 ttaccaagtg atttatctga aaaaacaact acattatcca atattcaatc gacagcagct
    20941 tatcaatcat tgacaagtga gcaacaaact gagataagtg attctgtatc tcaaaattca
    21001 actgatagta ttcaatcggc tcagtcaatt gtagctttag tacaagattt acagggaagt
    21061 ttagaaaact tacaaaatca atcttctaat ctttcgactt taaaaaatca atctaatcaa
    21121 gtatcaccta ttacttctac ttctttgata ggattgtcaa gtggattaac agagatacaa
    21181 ggagatgtta ctagcaaatt agttcctgcc agtcagtcga ttgcatcagg tgtaaacgca
    21241 tatactacag gtgttgataa agtttctcag ggcgcaagtc aactaagtga aaaaaatgcc
    21301 accttgacag gtagtttgga taaactagtt tcaggctcaa acaccttgac acaaaaatct
    21361 tctagattga cagcaggagt tggttaatta caatcaggat ctgggcaatt agcagacaaa
    21421 tccagtcagt tactttcagg tgcttctcca ttagagaata gagctaataa attggcagat
    21481 ggatctggga aactagcaga aggtggaaca aagttaactt ctggattgga agatttacag
    21541 acaggacttg cttctttagg acaaggacta ggtaatgcta gtgatcaact caaatcagta
    21601 tcaacagaat ctaaaaatgc agagattttg tcaaatccac tcaatctttc aaaaacagac
    21661 aatgatcaag ttcctgtaaa tggaatcgca atagctcctt atatgatatc agttgctctt
    21721 tttgttgcag caatatcaac aaatatgata tttgcgaaat tgccttcagg acgtcatcca
    21781 gagagccgtt gggcttggtt gaaatctcga gctgaaataa atggtattat agctgttttg
    21841 gcaggaattt tggtatatgg aggagttcag cttattggtt taactgctaa tcatgagatg
    21901 agaatattta ttctcatcat cctaacaagt ttagtattca tgtctatggt gaccacttta
    21961 acaacgtgga atagccgtat aggagctttt ttcttactta ttttgctttt actacagtta
    22021 gcatcaagtg caggtactta tccacttgct ttgacaaatg atttctttag atctattaat
    22081 ccctggttac caatgagcta ttcagtttcg ggattacgac aaacaatctc tatcaacaag
    22141 tcattttcct agctgtcata ctagctctat ttactggttt aggtatgcta gcctatcaac
    22201 ataagaaaat ggaagaagat taaaaaaatc gaccgattaa tgaactgcac cccaaaagtt
    22261 agacagaaaa aatctaactt ttgaggt
//
LOCUS       DAVBDR010000032        22017 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.032, whole genome shotgun sequence.
ACCESSION   DAVBDR010000032 DAVBDR010000000
VERSION     DAVBDR010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22017)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22017)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22017
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.032"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            51..233
                     /locus_tag="VQ540_001264"
     CDS             51..233
                     /locus_tag="VQ540_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000842022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HET2545069.1"
                     /translation="MKSQKIKVSFTQSKIVTPILLVNKTIVWYGAMPLLGKVDEMTIL
                     RLESASIVSELVAGLR"
     gene            533..1372
                     /locus_tag="VQ540_001265"
     CDS             533..1372
                     /locus_tag="VQ540_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HET2545070.1"
                     /translation="MIIKRILNHNAVIAQSKKDIDILLFGRGIAFGRKTGDKVNPIDI
                     EKSFFLKNRDNMTRFTEMFINVPLELVYITEKIINLGKITLGNNFDEIIYINLTDHIS
                     SSIERYKEGIIISNPLRWEISKYYKEEFELGKRALQIIKKELGIELPIDEAAFIALHF
                     VNANLENNFQESYKITEIIMGIEKIIQDFYCTEFNQDSIDYYRFITHIKLFAHRLVEN
                     TTYCDDDDEDLLALMKNKYPREYECGEQVAMFIQTEYNYLLTSSELVYLMAHIRRLTK
                     NLD"
     gene            1390..3228
                     /locus_tag="VQ540_001266"
     CDS             1390..3228
                     /locus_tag="VQ540_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HET2545071.1"
                     /translation="MSYKDTVQKILDVIGGEKNVNRVTHCVTRLRLELKDENLVNDDD
                     VKKIPDVIGIMKKNGQYQIILGNDVANYYKEFVKLGNFESDSVVQGHKGNILERIIEY
                     IAGSMTPIIPAMLGGGMLKVLVIILPMLGILQSDSQTIAFLTFFGDAPYYFLPLLLAY
                     SASQKLKVTSTLAMSVAGVLLHPNFVQMVQSGNPLSLFGAPVTPASYGSSVVPILIMV
                     WLMKYIEKIIAKLTPAITKSFLQPTLVLLVSSCIALVVVGPIGVIVGEGLSNLVGQMY
                     GVAGWLTLAILGAIMPFIVMTGMHWAFAPIFLAASIATPDVLILPAMLGSNLAQGAAS
                     MAVALKSKNNNTKQIAFAAGFSALLAGITEPALYGVTLKYKKPLYAAMIGGGLAGLFA
                     GLTSVKAYLFAVPSLIALPQFIYSDVPSNIVNALIVAVISVVITFVLAYIFGIDEEES
                     SSNLEVKAGVSNKKMIFSPISGEIIPLSDVQDKTFSDKLIGDGVAIIPSEGKVYAPFD
                     GKITNIFPTKHAIGLKSDEGVELLIHIGLDTVELKGQGFISHVEEGDRVFKNQLIFEM
                     NLNLIKTKGYETVTPVIVTNTNDFLDVLVLPNNQTIEHSKELLVIL"
     gene            3241..4656
                     /locus_tag="VQ540_001267"
     CDS             3241..4656
                     /locus_tag="VQ540_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HET2545072.1"
                     /translation="MTIFPDDFLWGGAVAANQVEGAYNEDGKGLSVQDVLPKGGLGEA
                     TENPTEDNLKLIGIDFYHKYKEDISLFSEMGFNVFRTSIAWSRIFPKGDEEEPNEAGL
                     KYYDELFDELHAHGIEPLVTLSHYETPLYLARKYHGWIDRRMIHFYEKFARTVLERYK
                     DKVKYWLTFNEVNSVLELPFTSGGIDIPKENLSKQELYQAIHHELVASSLVTKIAREI
                     NSEFKVGCMVLAMPAYPMTPNPKDVWATHEYENLNYLFSDVHVRGYYPNYAKRYFKEN
                     DINIEFAAEDAELLKNYTVDFLSFSYYMSVTQSAIPTQYNSGEGNIIGGLVNPYLESS
                     EWGWQIDPIGLRIILNRYYDRYQIPLFIVENGLGAKDQLIKDELNNLTVQDDYRIQYM
                     KEHLLQVAEALQDGVEIMGYTSWGCIDCVSMSTAQLSKRYGLIYVDRNDDGNGTFNRY
                     KKMSFTWYKGVIESNGESLFK"
     gene            5248..6294
                     /gene="pheS"
                     /locus_tag="VQ540_001268"
     CDS             5248..6294
                     /gene="pheS"
                     /locus_tag="VQ540_001268"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HET2545073.1"
                     /translation="MSTIEEQLKALREETLASLKQITAGNEKEMQDLRVSVLGKKGSL
                     TEILKGMKDVSAEMRPIIGKHVNEARDVLTAAFEETAKLLEEKKVAAQLASESIDVTL
                     PGRPVATGHRHVLTQTSEEIEDIFIGMGYQVVDGFEVEQDYYNFERMNLPKDHPARDM
                     QDTFYITEEILLRTHTSPVQARAMDAHDFSKGPLKMISPGRVFRRDTDDATHSHQFHQ
                     IEGLVVGKNISMADLQGTLQLIVQKMFGEERQIRLRPSYFPFTEPSVEVDVSCFKCGG
                     EGCNVCKKTGWIEIMGAGMVHPRVLEMSGIDATVYSGFAFGLGQERVAMLRYGINDIR
                     GFYQGDVRFSEQFK"
     gene            6294..6803
                     /locus_tag="VQ540_001269"
     CDS             6294..6803
                     /locus_tag="VQ540_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2545074.1"
                     /translation="MIRKVEMADVEVLAKIAKQAFRETFAYDNTEEQLQEYFEEAYSL
                     KTLSTELGNPDSETYFIMHEEEIAGFLKVNWGSAQTERELEDAFEIQRLYVLQKFQGF
                     GLGKQLFEFALELATKNSFSWAWLGVWEHNTKAQAFYNRYGFEKFSQHHFMVGQKVDT
                     DWLLRKKLR"
     gene            6880..9285
                     /locus_tag="VQ540_001270"
     CDS             6880..9285
                     /locus_tag="VQ540_001270"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HET2545075.1"
                     /translation="MLVSYKWLKELVGIDVPSQELAEKMSTTGIEVEGVESPAAGLSK
                     IVVGEILSCEDVPETHLHVCQVNVGEEEERQIVCGAPNVRAGIKVMVALPGARIADNY
                     KIKKGKIRGLESLGMICSLGELGISDSVVPKKFADGIQILPENAVPGEEVFSYLDLDD
                     EIIELSITPNRADALSMRGVAHEVAAIYDKAVNFKEFTLTETNEAATDALSVGIETDK
                     APYYAARILDNVTIAPSPQWLQNLLMNEGIRPINNVVDVTNYILLYFGQPMHAFDLDT
                     FEGTDIRVREARAGEKLVTLDGEERDLDVNDLVITVADKPVALAGVMGGQATEISEKS
                     SHVVLEAAVFNGKSIRKTSGRLNLRSESSSRFEKGINVATVNEALDAAASLIAELAGA
                     TVRKGIVSAGELDTSDVEVSSTLADVNRVLGTELSYADVEDVFRRLGFGLSGNADSFT
                     VSVPRRRWDITIEADLFEEIARIYGYDRLPTSLPKDDGTAGELTVTQKLRRQVRTIAE
                     GAGLTEIITYVLTTPEKAVEFTAQPSNLTELMWPMTVDRSVLRQNMISGILDTVAYNV
                     ARKNKNLALYEIGKVFEQTGNPKEELPNEINSFAFALTGLVAEKDFQTAAVPVDFFYA
                     KGILEALFTRLGLEVTYTATAEIASLHPGRTAVISLGDQVLGFLGQVHPVTAKAYDIP
                     ETYVAELNLSVIEAALQPAAPFVEITKFPAVSRDVALLLKAAVTHQEVIDAIQAAGVK
                     RLTDIKLFDVFSGEKLGLGMKSMAYSLTFQNPEDSLTDEEVARYMEKIQASLEKKVNA
                     EVR"
     gene            complement(9458..10459)
                     /locus_tag="VQ540_001271"
     CDS             complement(9458..10459)
                     /locus_tag="VQ540_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000597989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HET2545076.1"
                     /translation="MIKTFLSALSVILFVIPIITYSFFPSSNLNIWLSTRPILAQIYA
                     FPLATATMAAILSFVFFSLSFYKKNKQIRFYSGILLLLSLILLLFGTDKTLSSASNKT
                     KTLKLVTWNVANQIEAQHIERIFSHFDADMAIFPELATNIRGEQENQRIKLLFHQVGL
                     SMANYDIFTSPPTNSGIAPVTVIVKKSYGFYTEAKTFHTTRFGTIVLHSRKQNIPDII
                     ALHTAPPLPGLMEIWKQDLNIIHNQLASKYPKAIIADDFNATMRHGALAKISSHRDAL
                     NVLPPFERGTWNSQSPKLFNATIDHILLPKNHYYVKDLDIVSFQNSDHRCIFTEITF"
     gene            10615..11103
                     /locus_tag="VQ540_001272"
                     /pseudo
     CDS             10615..11103
                     /locus_tag="VQ540_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            11187..11453
                     /locus_tag="VQ540_001273"
     CDS             11187..11453
                     /locus_tag="VQ540_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET2545077.1"
                     /translation="MEGCPSELFSKEEILESDMRVAIMSELIEARYEQGISQKKLEEV
                     SGVSQPVIARMETGESSLQLDTVLKVLTSLGKTLAVVPLEQGKS"
     gene            11714..13963
                     /gene="metE"
                     /locus_tag="VQ540_001274"
     CDS             11714..13963
                     /gene="metE"
                     /locus_tag="VQ540_001274"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HET2545078.1"
                     /translation="MSTTIIGFPRLGEFRELKFTTEKYFRKEISEEELLAAAKDLRAK
                     HWNIVKEKGITEIPSNDFSHYDNFLDAAFLFNVVPASVQNLDLSDLERYFALGRGYQG
                     EKGDVRALPMKKWFNTNYHYIVPKFEKDTQVKLAGHKIFDEFQEAKELGLNTRPVLVG
                     PFTFLQLSDFEEGVKADDFVDSLVAAYQEVFAKLAELGATRIQLDEAALVKDLTAEEK
                     ALFLNLYNKLLADKKGLEVLLQTYFGDVRDVYADLVNLPVDAIGLDFVEGKKTLELVK
                     GGFPADKTLYVGIVNGKNIWRNNYEKSLAVLEQIPAENIVLTSSCSLLHVPFTTANEE
                     FEPALLNHFAFAVEKLDEIRDLDAIRNGQGSEALAANKELFATERVGENAELRARIAG
                     LTDADYTRLPAFAEREAIQEEAFKLPALPTTTIGSFPQTKEVRAKRLAYRKGELSQKE
                     YDAFLAETIDEWIKWQEDIDFDVLVHGEFERNDMVEYFGQNLSGYLFSKNGWVQSYGM
                     RGVKPPIIWGDVTRLNPITVKWSSYAQSRTNKPVKGMLTGPVTILNWSFPREDISIKD
                     STLQIALAIKDEVLDLEAAGVKIIQIDEAALREKLPLRRSDWYEDYLDWAIPAFRLVH
                     STVASDTQIHTHMCYSEFTDIIPAIDNMDADVISFEASRSNLEILDELKAKNFQTEVG
                     PGVYDIHSPRVPNEGEIDNTIEAILAKVPSKKVWINPDCGLKTRGIPETKESLIRLVE
                     AAKAAREKL"
     gene            14027..14893
                     /gene="metF"
                     /locus_tag="VQ540_001275"
     CDS             14027..14893
                     /gene="metF"
                     /locus_tag="VQ540_001275"
                     /EC_number="1.5.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000089969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase [NAD(P)H]"
                     /protein_id="HET2545079.1"
                     /translation="MSRQTPSLSFEVFPPNPAVGNGNIISALQDMQELAPHFISVTAS
                     NNKFNIKETTVRLADFIQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALR
                     GDIIPDVEPQKDFRYATDLIEFIKEQAPHFDIIGACYPEGHPDSPNQISDIQNLKKKV
                     DAGCSSLVTQLFFDNERFYDFQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIH
                     LPRKFKAILDKYEHDPESLRAAGLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQ
                     ATHALFNHQSLG"
     gene            15578..17791
                     /gene="pnp"
                     /locus_tag="VQ540_001276"
     CDS             15578..17791
                     /gene="pnp"
                     /locus_tag="VQ540_001276"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001854499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HET2545080.1"
                     /translation="MAKQVFQTTFAGRELIVETGQVAKQANGSVVVRYGESTVLTAAV
                     MSKKMATGDFFPLQVNYEEKMYAAGKFPGGFMKREGRPSTDATLTARLIDRPIRPMFA
                     EGFRNEVQVINTVLSYDENASAPMAAMFGSSLALSISDIPFDGPIAGVQVGYVDDQII
                     INPSQEQAEQSLLELTVAGTKHAINMVESGAKELSEEIMLEALLKGHEAVKELIAFQE
                     EIVAAVGKEKAEVELLHVDAELQAEIIAAYNSDLQKAVQVEEKLAREAATQAVKDQVT
                     AVYEEKYADHEEFDRIMRDVAEILEQMEHAEVRRLITEDKVRPDGRKVDEIRPLDAVV
                     DFLPRVHGSGLFTRGQTQALSVLTLAPMGETQIIDGLDPEYKKRFMHHYNFPQYSVGE
                     TGRYGAPGRREIGHGALGERALAQVLPSLEEFPYAIRLVAEVLESNGSSSQASICAGT
                     LALMAGGVPIKAPVAGIAMGLISDGNNYTVLTDIQGLEDHFGDMDFKVAGTRDGITAL
                     QMDIKIQGITAEILTEALAQAKKARFEILDVIEATIPEVRLELAPTAPKIDTIKIDVD
                     KIKIVIGKGGETIDKIIAETGVKIDIDEEGNVSIYSSDQDAINRAKEIIAGLVREAKV
                     DEVYRAKVVRIEKFGAFVNLFDKTDALVHISEMAWTRTNRVEDLVEIGDEVDVKVIKI
                     DEKGRIDASMKALLPRPPKPEHDEKGEKSERPHRPRHHKDHKPKKEFTETPKDSE"
     gene            17807..18424
                     /gene="cysE"
                     /locus_tag="VQ540_001277"
     CDS             17807..18424
                     /gene="cysE"
                     /locus_tag="VQ540_001277"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000539958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HET2545081.1"
                     /translation="MGWWRETIDIVKENDPAARTTLEVLLTYPGVKALAAHRLSHFIW
                     KHGFKLLARMHSQFWRFWTQIEIHPGAQIDSGVFIDHGSGLVIGETAIVEKGVLLYHG
                     VTLGGTGKDCGKRHPTVRKGALISAHAQVIGPVEIGENAKVGAAAVVVADVPSDVTVV
                     GIPAKIVRLHGKKDEPVIHEVEEKREYYVNKLEQAKDASHRSSGL"
     gene            18436..19320
                     /locus_tag="VQ540_001278"
     CDS             18436..19320
                     /locus_tag="VQ540_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2545082.1"
                     /translation="MIQVRNKLSQEELSEAKKVINCCQNYDGTYRDPYLSNMLNFDPN
                     MPAFFLYYEKGELVGLLTVYADDQDVEVTILVHPGHRRQGIARALFTSFERETASFPI
                     RSVTFQTERIFLENHPDFASNWGLIEDEETETWLGKDRRPYPLANVSHIEVLLADSSY
                     QDQISQLKFQAFSEEHESREVVDRYVAEALKDPESRLYILLKDGQVIGTCTVDLSTNT
                     NYFYGLAISEPERGKGYGSYLAKSLVNQLIEQNDKEFQIAVEDSNVGAKRLYEKIGFV
                     KQTQVVYLNEKGARDSEV"
     gene            19402..20745
                     /locus_tag="VQ540_001279"
     CDS             19402..20745
                     /locus_tag="VQ540_001279"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002916477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HET2545083.1"
                     /translation="MIKIYDTMSRDLREFVPIEDGKIKMYVCGPTVYNYIHVGNARST
                     VAFDTIRRYFEYRGYEVAYISNFTDVDDKIINRAREEGITPQEVADKYIAAFREDVTA
                     LGVKPATRHPRVVEFMADIIRFVEGLIEKGFAYESQGDVYFRVEKSHNYAKLANKTLE
                     DLELGASGRTDEETARKENPVDFALWKSSKPGEISWDSPWGPGRPGWHIECSVMSTEI
                     LGDTIDIHGGGADLEFPHHTNEIAQSEAKTGKAFANYWMHNGFVNIDNVKMSKSLGNF
                     ITVHDALKTLDGQVLRFFFATQHYRKPINFTEKAVRDAETNLKYLKNTYEQPFTGNVD
                     AQELQNFKDKFVAAMDEDFNAANGITVVFEMAKWINSGNYDASVKQALADMLEIFGIV
                     FVEEVLDAEIEDLIQKRQEARANRDFATADQIRDQLVTQGIKLLDTKDGVRWTRD"
     gene            20738..21124
                     /locus_tag="VQ540_001280"
     CDS             20738..21124
                     /locus_tag="VQ540_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HET2545084.1"
                     /translation="MIDVNLINGIALAFEGDAVYSMYIRRHLILKGMTKPNKLHQEAT
                     KYVSAKAQARLISLMLEEQILTEKEEEIYKRGRNTNSHTKAKNADVVTYRMSTGFEAV
                     MGYLHMTENLERLESLVSWCIQKVEG"
     gene            21128..22012
                     /locus_tag="VQ540_001281"
     CDS             21128..22012
                     /locus_tag="VQ540_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PucR family transcriptional regulator"
                     /protein_id="HET2545085.1"
                     /translation="MRAKELQDWFPEARISDQPVEKEGYLTLPLASQQWILLEEAGLS
                     EREKQLVALLTQQEQARSLNPWYSYLVEGKGQAPQVFKKIQLVYCHLSYFQQENLASW
                     LDMMRTLFPNCQTVLQVGAQDYVFVLQQDKYTSVRDILSDMIEAVEYDFGLRLSIMLG
                     QVWSQTGHQALSDLIKAERDLFKTWWRQGHQGVHTFSQLYLWSMGERLVDLKPIKECL
                     HQMILDQDQIQEIILSLWENSAVLTKTAQQLYLHRNSLQYKIDKWEELTGLQLKELTD
                     LTLCYQLILGSLSTIVGL"
BASE COUNT         6764 a         3965 c         4861 g         6427 t
ORIGIN      
        1 accccaaaag ttagattttt tctgtctaac ttttggggtg tagttcacag ttgaagagcc
       61 agaaaattaa agtgtctttt actcaatcaa aaatagtaac gcctattctt ttggtgaata
      121 agactattgt ttggtatggt gcaatgccat tattagggaa ggtagatgag atgaccatat
      181 tacgtttgga atcagctagt atagtttctg aactagtggc aggtttacga tagagaaaat
      241 ttttaaaaat ttctatgtat gattttcatt tctttagtga gactgttgcc attatcacat
      301 tcgaatcaca caaaataaaa aaatttctac aagtacttga caaatagatt gaaatatcat
      361 aaaatgaaaa tggttacaga gttattaatt atttaagctt catgtcacca ttaaaaattg
      421 aaataaaagg atgttatcac taatacaagt gagcaggaac ctatttaatc acatcggaag
      481 aagtttcttg atgtttttaa gtaggttcct tttattttaa aagggaaatt ttatgatcat
      541 aaaacgaata ctaaaccaca atgccgtaat tgcgcaaagt aaaaaagata tcgatattct
      601 tctttttgga aggggcatag cttttggaag aaaaactgga gataaagtaa atccaattga
      661 tattgagaaa agtttttttc tcaaaaatag agataatatg acccgtttta cagagatgtt
      721 tattaacgtt cctttggagt tggtgtacat caccgaaaaa ataattaacc taggtaaaat
      781 aacattgggt aataattttg atgaaattat ctatattaat ttaacggatc atatttcttc
      841 gagcatagaa cgttataaag aagggattat tatttcgaat cccctacgct gggaaatatc
      901 gaaatattat aaagaagaat ttgaacttgg gaaaagggct ttacaaataa taaaaaaaga
      961 gttaggtatt gaacttccaa ttgacgaagc tgcattcata gcgctacatt ttgttaatgc
     1021 taatttagaa aataattttc aagagtcgta taaaatcact gaaataatta tgggaattga
     1081 gaaaatcatt caagatttct attgtactga gtttaaccaa gattctattg attattatag
     1141 attcataact catataaaat tatttgctca tcgcttggtt gaaaatacaa cttattgtga
     1201 cgatgatgat gaagacttgt tagcattaat gaaaaataaa tatcctagag aatatgaatg
     1261 tggtgaacag gtggcaatgt ttatacaaac tgagtacaat tatttgctga cttctagtga
     1321 attagtttat ttgatggctc atattcgtcg cttaacaaaa aatttagatt aatagaatag
     1381 gagaatacca tgagttataa agatacggta caaaaaatcc tcgatgtaat tggaggtgaa
     1441 aaaaatgtca atagagttac ccattgtgta acacgtttaa gattagaatt aaaagatgaa
     1501 aatttagtca atgatgatga tgtgaagaag ataccagatg taataggtat tatgaaaaag
     1561 aatggacaat atcaaattat acttggtaat gatgtagcta attattataa agaattcgtt
     1621 aaacttggca attttgaatc cgattcagtt gttcaagggc acaaagggaa tattttagaa
     1681 agaatcattg agtatatcgc tggttccatg actccaatca ttccagcaat gttaggggga
     1741 ggtatgttga aagtcttggt aatcatttta ccaatgcttg gtatattgca atcagattct
     1801 cagactattg cttttttgac attttttggg gatgctccat attatttctt accgctgtta
     1861 ttagcttatt ctgcatcaca aaaattaaaa gtaacatcta cattagctat gtctgtagca
     1921 ggtgtacttc tccatccaaa ttttgttcaa atggtgcaat cagggaatcc tcttagttta
     1981 tttggtgcac ctgtgacacc agctagttat ggttcatcag tcgttccaat tcttattatg
     2041 gtttggttga tgaaatatat tgaaaaaata attgctaaat taacaccagc tattactaag
     2101 agttttttgc aacctacgct agtattatta gtatcaagct gtattgcctt agttgtagtc
     2161 ggacctattg gagtaattgt tggtgaagga ttatcaaatc tagttgggca aatgtatggt
     2221 gtagctggat ggcttacatt agctattctt ggtgctatta tgccatttat tgttatgact
     2281 ggaatgcatt gggcttttgc acctattttt ttggcggcat ctattgctac tccagacgta
     2341 ttaattcttc cagcaatgtt agggtcaaac ttagctcaag gggctgcttc gatggctgtt
     2401 gcattaaaga gtaaaaataa taatacaaaa caaattgctt ttgcagcagg tttctcagcc
     2461 ttacttgcag ggattaccga acctgcatta tatggtgtga ctttaaaata taaaaaaccg
     2521 ctttatgcag ctatgattgg tggtggatta gcgggattat ttgcaggtct tactagtgtt
     2581 aaagcatatc tatttgctgt cccatctttg atagcgttgc ctcaatttat ttattctgat
     2641 gtgccatcaa atattgtaaa tgctttaatt gtggcggtca tttcggttgt tattaccttt
     2701 gtattagctt atatatttgg aatcgatgaa gaagagagtt ctagcaattt agaagttaaa
     2761 gctggagttt caaataaaaa aatgatattt tctcctatat caggagaaat cattccgtta
     2821 agcgatgtcc aggataaaac attttcagat aaattaattg gagacggagt agcgattatc
     2881 ccaagtgaag gtaaggttta tgcaccattt gatgggaaaa ttacaaatat ttttccgact
     2941 aagcacgcaa ttggattgaa gagtgatgag ggtgttgagt tactaattca tattggatta
     3001 gatactgttg agctaaaagg tcaaggtttt attagtcatg tagaagaagg agacagagtt
     3061 ttcaaaaatc agttgatttt tgaaatgaac ttgaatttaa tcaagactaa aggctacgaa
     3121 acagttacac cagtaattgt aacgaatacc aatgattttc tagatgtatt agtattacct
     3181 aataatcaga caatcgagca ttctaaggaa ttactggtaa tattataatg gaggaaagtt
     3241 atgaccattt ttccagatga ttttctttgg ggtggagcgg ttgcagctaa tcaagtagag
     3301 ggagcatata atgaagatgg taagggctta tcagttcagg atgtgttacc caaaggtgga
     3361 ttaggagaag caacagaaaa tcctacagaa gataacttaa aattgatagg tattgatttt
     3421 tatcataaat ataaggaaga tatatccttg ttttctgaaa tgggctttaa tgtttttcgt
     3481 acttctattg catggagtag aatttttcca aaaggagatg aggaagaacc taacgaagct
     3541 ggtttgaaat attatgatga attatttgat gaactacatg ctcacgggat agaaccactt
     3601 gtaactcttt cacactatga gactccatta tatttagcaa gaaaatatca tggatggatt
     3661 gataggagaa tgattcattt ttatgaaaaa tttgctcgaa cagttttaga aaggtataaa
     3721 gataaagtta aatattggct tacatttaac gaagtaaact ctgttttgga attaccgttt
     3781 actagtggag gaatagatat acctaaggag aatctttcga aacaagaatt atatcaagct
     3841 atacatcatg aattagtcgc ctcgagtttg gttacaaaaa ttgctcgtga gattaattca
     3901 gagtttaagg tggggtgtat ggtattagct atgccagctt atccaatgac tccaaatcca
     3961 aaagatgtat gggcgactca tgagtatgag aatctaaatt atctattttc agatgtgcat
     4021 gttagaggtt attatccgaa ttatgcaaaa agatatttta aggaaaatga cattaacata
     4081 gagtttgcag ctgaagatgc agagttatta aaaaattata ctgtagattt tttatccttt
     4141 agctattaca tgagtgtgac tcaatctgct attccaacac agtataattc aggagaaggg
     4201 aatattattg gtggtttagt aaatccttat ttagagtctt cagagtgggg atggcaaatt
     4261 gatccaattg gactacgtat aattttaaat agatattatg accgttatca aatcccatta
     4321 tttatagtag aaaatggatt aggtgctaaa gatcaactaa taaaagatga acttaataac
     4381 ttaaccgtcc aagatgatta tagaattcag tatatgaaag aacatttatt gcaagttgct
     4441 gaagctctac aggatggtgt tgaaattatg ggctatacgt cttggggatg tattgactgt
     4501 gtttctatgt ccactgcaca actttctaaa aggtacggtc tcatttatgt tgatcgaaat
     4561 gatgatggaa atggcacatt caatcgatat aagaaaatgt cctttacttg gtataaagga
     4621 gtgattgaat caaatggaga atccttattc aaatagtttg tttattgatg attagatatt
     4681 atcacggtta aggcaacatc tcattaaata taaaataaag aggtttggaa gacatcaaat
     4741 tctaaacctc tttattttat agggggatta attaatttaa ttttgttaca gagagccgat
     4801 tataaatagt taacttagga tagattggtt atatatagta gactgaatct aaaatagtac
     4861 gaaacaattg ctaaaacatt tatagaaatt aattttactt tcccaatcga tttgttttca
     4921 tcttatttca atccgctata aagttagata agaataagct aacaagcaga agtaagatag
     4981 gtcttgcaag aatggtaaaa atctgataaa ctaagtagta attgaatagg aatctgaaag
     5041 actagtagcc caagggaagt atatcaggga ggagagccgt gactgcaagc tctctatatg
     5101 aaagctgggt gaattcactt gcgcatggat ttagaaatga aggtctgact tgtcagatga
     5161 aaacggatgg taccgcgtgt caacgctccg agtggagttt ttggcatgtg gttttctttt
     5221 tatctacgag agactgatgg aggaaatatg tcaactattg aagaacaatt aaaagcgctt
     5281 cgcgaagaaa cgctggctag cttgaagcag attactgctg gaaatgaaaa agagatgcaa
     5341 gatttgcgtg tctctgtcct tggtaaaaag ggttcgctca ctgaaatcct caaagggatg
     5401 aaagatgttt ctgctgagat gcgtccaatc atcgggaaac acgtcaatga agctcgtgat
     5461 gtcttgactg ctgcttttga agaaacagct aagctcttgg aagaaaagaa agtcgcggct
     5521 caactggcta gcgagagtat cgatgtgacg cttccaggtc gtccagttgc gactggtcac
     5581 cgtcacgttt tgacacaaac cagtgaagaa atcgaagata tcttcatcgg tatgggttat
     5641 caagtcgtgg atggttttga agtggagcaa gactactata actttgaacg tatgaacctt
     5701 ccaaaagacc acccagctcg tgatatgcag gatactttct atatcactga agaaatcttg
     5761 ctccgtaccc acacgtctcc agttcaggcg cgtgctatgg atgcccatga tttttctaaa
     5821 ggtcctttga agatgatctc gccagggcgt gtcttccgtc gcgatacgga cgatgcgacc
     5881 cacagtcacc aattccacca aatcgaaggc ttggtagttg ggaaaaatat ctctatggct
     5941 gatcttcaag gaacgcttca gttgattgtc caaaaaatgt ttggtgaaga gcgtcaaatt
     6001 cgtttgcgtc catcttactt cccattcaca gagccatctg ttgaggtgga tgtttcttgc
     6061 ttcaagtgtg gtggagaagg ctgtaatgta tgtaagaaaa caggttggat cgaaattatg
     6121 ggggccggta tggttcaccc acgtgtcctt gaaatgagtg gtatcgatgc gactgtatac
     6181 tctggctttg cctttggtct tggacaagag cgtgtagcta tgctccgtta tggaatcaac
     6241 gatatccgtg gattctacca aggagatgtc cgcttctcag aacagtttaa ataatgatta
     6301 gaaaagtaga aatggcagat gttgaggtgt tggctaaaat tgccaaacaa gcctttcgtg
     6361 aaacctttgc gtatgataat acggaagagc agttacagga atactttgaa gaggcttata
     6421 gtctgaaaac tttgtcaact gagttgggaa atcctgactc tgaaacctat ttcattatgc
     6481 atgaggagga gatagctggt tttctcaaag tcaactgggg aagtgctcaa actgagagag
     6541 aattagagga cgcttttgaa attcaacgcc tctatgtgct acaaaaattc caaggatttg
     6601 gactaggtaa gcaactgttt gaattcgcac ttgaacttgc tacaaaaaat agtttttctt
     6661 gggcttggct aggtgtttgg gagcataata caaaagctca agcgttttat aaccgatatg
     6721 gttttgaaaa atttagccaa catcatttta tggttggtca aaaagtagat acggattggt
     6781 tactgagaaa gaaattaagg taagaagaga attcttctat tgaaatgata ggaaaggaaa
     6841 agaaccagtg tggcaatggt cattctggag aactaaatta tgcttgtatc ttataaatgg
     6901 ttaaaagaat tggtgggcat tgatgtgcca tcacaggagt tggctgaaaa aatgtcaacc
     6961 acagggatcg aggtcgaagg tgtcgaatca ccagctgccg gtctttcaaa aattgtcgtc
     7021 ggtgagatct tgtcttgcga agatgtgcca gaaactcacc ttcatgtttg tcaggttaac
     7081 gttggcgaag aagaagagcg tcagatcgtt tgtggtgccc caaatgtgcg tgcaggcatc
     7141 aaggttatgg tggctcttcc gggagctcgt atcgctgaca attacaaaat caaaaaagga
     7201 aaaatccgtg gcttagagtc acttggaatg atctgttcac ttggtgaatt gggtatttct
     7261 gactcagttg tacctaagaa attcgcagat ggtattcaaa ttttgccaga aaatgccgtt
     7321 ccaggtgagg aagtcttttc atatctagac ttggatgatg aaatcatcga actttctatc
     7381 acaccaaacc gtgcagatgc cctttctatg cgtggagtgg ctcacgaagt ggcagccata
     7441 tatgacaagg cagtcaactt taaagaattt actttgacag aaacaaatga agctgcgaca
     7501 gatgcccttt ctgtgggcat tgagacagac aaggcgcctt actatgcagc tcgtatcttg
     7561 gacaatgtga ctatcgcacc aagtccacaa tggttgcaaa accttctcat gaacgaaggc
     7621 atccgtccca tcaataacgt tgtagacgtg acaaactaca tcctgctcta ctttggtcaa
     7681 cctatgcatg cttttgactt ggacacattt gaagggactg acatccgtgt gcgtgaagcg
     7741 cgtgctggtg aaaaattggt gaccttggac ggtgaagaac gtgacttgga cgtgaatgac
     7801 ctagtcatca ctgttgcaga caagccagta gcccttgcag gtgtcatggg tggtcaagca
     7861 acagaaatct ctgaaaaatc tagtcatgtt gtccttgaag ctgctgtttt caatggcaaa
     7921 tctatccgta agacaagtgg tcgcctgaac cttcgttctg agtcatcttc tcgctttgaa
     7981 aaaggaatta atgtggcaac agttaatgaa gcccttgatg cggcagctag cctgattgcg
     8041 gaacttgcag gtgcgacggt gcgtaagggt atcgtttcag cgggtgagct tgatacttca
     8101 gatgtagaag tttcttcaac tcttgctgat gttaaccgtg tcctcggaac tgagctgtct
     8161 tatgctgatg tcgaagacgt cttccgtcgt cttggctttg gtctttctgg aaatgcagac
     8221 agctttacag tcagcgtacc acgtcgtcgt tgggatatca caatcgaagc tgatctcttt
     8281 gaagaaatcg ctcgtatcta tggatatgac cgcttgccaa ccagccttcc aaaagacgat
     8341 ggtacagctg gtgaattgac tgtgacacaa aaactccgcc gtcaagttcg taccattgct
     8401 gaaggagcag gtttgacaga aatcatcacc tatgttctaa caactcctga aaaagcagtt
     8461 gagtttacgg ctcaaccaag taaccttacg gaactcatgt ggccaatgac tgtggatcgt
     8521 tcagtcctcc gtcaaaatat gatttcaggt atccttgata ccgttgccta caacgtggct
     8581 cgtaagaata aaaacttggc cctttacgag attggaaaag tctttgaaca aacaggtaat
     8641 ccaaaagaag aacttccaaa tgaaatcaac agttttgcct ttgccttgac aggcttggtt
     8701 gctgaaaaag atttccaaac agcagcagtt ccagttgatt tcttctatgc taaaggaatc
     8761 ctagaagcgc tctttactcg cttgggacta gaagtgacct atacagcaac agctgagatt
     8821 gccagccttc acccaggacg tacagcagtc atttcactcg gtgaccaagt tcttggtttt
     8881 cttggccaag tgcatccagt cactgctaag gcttacgata ttccagaaac gtatgtggct
     8941 gagctcaacc tttcagtcat cgaagctgcc cttcaacctg ctgctccatt tgtggaaatc
     9001 acgaaattcc cagcagtcag ccgtgacgtt gcccttctcc tcaaggcagc agtaactcac
     9061 caagaagtta tagatgctat ccaagctgcc ggcgtgaaac gtttgacaga tatcaaactc
     9121 tttgacgttt tctcaggtga gaaattggga cttggtatga agtcaatggc ttatagcttg
     9181 accttccaaa atccagaaga cagcttaacg gacgaagaag tcgcacgcta catggaaaaa
     9241 atccaagcat cgcttgaaaa aaaagtgaac gcagaagtgc gttaaacgat agtaggatac
     9301 aaattccccc tctagtttat gaacactaga ggggtgattt tatataatac tcaatgaaaa
     9361 tcaaaaagca aactaggaag ctagccgtaa gctgtacttg agtactgtaa ggcgaggctg
     9421 acgtggtttg aagagattgt cgaagagtat aaaataatta aaatgtgatt tctgtaaaaa
     9481 tacatctatg atcagagttt tgaaaactta caatgtctaa atctttaaca tagtagtggt
     9541 ttttaggcaa taaaatatga tctattgttg cattaaaaag ttttggactt tggctattcc
     9601 aagttcctct ttcaaaaggt ggtagtacat ttaatgcgtc cctatgagag cttatttttg
     9661 caagtgctcc atgacgcata gttgcattaa aatcatctgc aataatagcc tttggatatt
     9721 ttgaagccaa ttgattatga atgatgttta agtcttgctt ccagatttcc attaaacctg
     9781 gcagaggagg agcagtatgc aaggcaatga tatctggtat attttgtttt ctcgaatgta
     9841 atacaattgt cccgaaccgt gttgtatgaa aagttttagc ttctgtatag aaaccataac
     9901 ttttcttgac aatcacagtc acaggagcta ttccactatt ggtaggtgga gaagtgaaaa
     9961 tatcatagtt ggccatagaa agtccaactt gatgaaacaa tagtttgatt ctctggtttt
    10021 cttgctcacc tctgatattg gtagctagtt cagggaatat agccatatcg gcgtcaaaat
    10081 ggctaaaaat tcgctcaata tgttgtgctt ctatttgatt agcgacgttc caagttacta
    10141 attttaaggt tttagtctta tttgatgcag aagaaagggt tttatctgtt ccgaataata
    10201 gtaatatgag cgatagtaag agcaaaatgc cagagtaaaa ccgtatttgt ttatttttct
    10261 tgtaaaaaga tagggaaaaa aatacgaaac ttaaaatagc agccatagtt gcagtagcta
    10321 aggggaaggc ataaatctgt gccaagatag gtctggtaga tagccaaata ttaagattag
    10381 aagatggaaa aaaagaataa gttatgatag ggataacaaa gagaatgacc gaaagggcag
    10441 agagaaatgt tttaatcatt gtgtgagtac ctcaatttgc aatggttgct cggagctaat
    10501 gtgactttgt gactttactt gattgatatt ctttttcttg tcttcctcat agattaagta
    10561 caacccaagt aaaaaaagtc caatttaaga ttgaaatgat taaaaggcac agaaatgcaa
    10621 gacaattata ctacaaaagg caaacatttg acaatcgata gccgtcgctt aatcgaaaga
    10681 tggaaaaaag aagggaaatc aaatagagaa attgcctctc tgcttggaaa agttcctcaa
    10741 actatccaca ctgaaatcaa gcgtgggaca gtccgacaat gtcttggaaa agggcgcttc
    10801 aaagaggttt attctgccga ctatgctcaa cagtcttatg aaaacaatcg caagcgctcg
    10861 gtcaagaaat caagcttgac caaggaacta aaggaaaaga ttctccacta tcataaccaa
    10921 aaattttcgc ttgaaatgat ggtgatggct aaaggggtta acgtgggaat ttcaaccatt
    10981 tactattgga ttcatcgtgg aaaattgggg ttaagcaagc aggatctgct ttaccctaga
    11041 aaaggaaaag cgcttaagaa acaggctagc accaacttta aacctgctgg tcaatctatc
    11101 gaatcataat tcgctcattc ttttaaaaat acatagacgt aaaagaaaga gggttaagtg
    11161 atgaagaata gtgctattgg gagtaattgg aaggatgtcc atctgagctc tttagcaagg
    11221 aggaaatcct tgaaagtgat atgcgagtgg ctatcatgag cgagttgatt gaggctaggt
    11281 atgaacaagg aatcagtcag aaaaagctgg aagaagtcag tggagtgagt caacctgtca
    11341 tagctaggat ggaaacagga gagagcagtc ttcagttgga tacggtctta aaagttctaa
    11401 ccagtctagg aaagacacta gcagtcgttc cacttgaaca ggggaaaagt tgactagaat
    11461 cagttatagt cttttctaat aacaggtcat agtcacttat aagaattact aataacatgt
    11521 tttagtattc taattggaat atagctgtaa agtaagaatt acaaaggatt tgagacgttt
    11581 gcttcaagtc tttttctttt gtccgaaaca gatatatagt ttcaaactat atcaaaccct
    11641 aattttttac aattatacag acgctttctt ttctgttaag atagtttcaa caacaaattt
    11701 tggaggacac atcatgtcaa ctacaatcat cggtttccct cgtttgggcg aattccgtga
    11761 attaaaattt acaactgaaa aatactttag aaaagaaatc tcagaagaag aacttttagc
    11821 agcagcaaaa gacttgcgtg ctaaacactg gaacattgtc aaagaaaaag gcatcactga
    11881 aattccatca aatgactttt ctcactatga taacttccta gatgcggctt tccttttcaa
    11941 cgtggtgcct gcatccgttc aaaacttgga cttgtctgac cttgagcgct acttcgcttt
    12001 gggacgtggt taccagggag aaaaagggga cgttcgcgcc cttccaatga agaaatggtt
    12061 caacactaac taccactaca tcgttcctaa atttgaaaaa gacactcaag taaaattggc
    12121 tggtcacaag attttcgatg agttccaaga agccaaagaa cttggattga acactcgtcc
    12181 tgttcttgta ggtcccttca ctttccttca attgtcagac tttgaagaag gcgtgaaagc
    12241 agacgacttc gtagatagct tagtggctgc ttaccaagaa gtttttgcta aattggctga
    12301 acttggtgcg actcgcatcc aattggatga agcggctctt gtaaaagact tgacagctga
    12361 agaaaaagct ctcttcttga acctttacaa caaactcttg gctgacaaaa aaggtcttga
    12421 agtcttgctt caaacttatt tcggtgatgt tcgtgacgta tacgctgacc ttgtaaactt
    12481 accagtagat gctatcggtc ttgactttgt tgaaggtaag aaaactcttg aactcgttaa
    12541 aggtggcttc ccagctgaca agactctcta tgtaggtatt gtcaatggta aaaacatctg
    12601 gcgcaacaac tacgaaaaga gcttggctgt tcttgagcaa attccagctg aaaacatcgt
    12661 tttgacaagc tcttgctcac ttcttcatgt gccatttaca actgctaatg aagaatttga
    12721 accagcactc ttgaaccact ttgcctttgc agttgaaaaa ttggatgaaa tccgtgactt
    12781 ggatgctatc cgcaatggtc aaggttcaga agctcttgca gccaacaaag aactctttgc
    12841 gactgagcgt gttggtgaaa atgctgaact tcgtgcgcgt atcgctggct tgacagacgc
    12901 agactacact cgtttgccag cctttgcaga acgtgaagct atccaagaag aagctttcaa
    12961 acttccagct cttccaacaa caacgattgg ttcattccct caaacaaaag aagttcgtgc
    13021 caaacgtttg gcttaccgta aaggtgaatt gtctcaaaaa gagtacgatg ctttccttgc
    13081 tgaaacgatt gacgaatgga tcaagtggca agaagatatt gactttgatg tccttgttca
    13141 cggtgaattt gagcgtaatg acatggttga gtacttcggt caaaacttgt caggatacct
    13201 cttctctaaa aatggatggg tacaatcata cggtatgcgt ggggtaaaac caccaatcat
    13261 ctggggtgat gtcactcgtc ttaaccctat cactgttaaa tggtctagct atgcacaaag
    13321 tcgtacaaac aaacctgtta aaggtatgtt gactggacct gttaccatcc ttaactggtc
    13381 attcccacgt gaagacatct ctatcaagga ttctactctt caaatcgccc ttgctatcaa
    13441 ggatgaagtg cttgaccttg aagctgctgg tgtgaaaatc atccaaattg atgaggctgc
    13501 tcttcgtgaa aaattgccac tccgtcgtag tgactggtac gaagattacc ttgactgggc
    13561 aattcctgcc ttccgcttgg tacactcaac agtagcgtca gacacacaaa tccacactca
    13621 catgtgttac tcagaattta cagatatcat cccagctatc gataacatgg atgcagacgt
    13681 tatttccttt gaagccagcc gttcaaacct tgaaatcttg gacgaactca aagcgaaaaa
    13741 cttccaaaca gaagtgggac ctggggttta cgatatccac tcacctcgtg taccaaatga
    13801 aggcgaaatc gacaacacaa tcgaagccat ccttgctaaa gtgccaagca agaaagtttg
    13861 gatcaaccct gactgtggtt tgaaaacacg tggtatccca gaaacaaaag aaagcttgat
    13921 ccgccttgtt gaagcagcta aagctgcgcg tgagaaattg taagattgga tttctctcca
    13981 tacagtggtt gttcaaaaag aaatcaacta gaaaaggtta ttacatatgt cacgccaaac
    14041 accgtcactc tcatttgaag tgttccctcc aaacccagcc gtgggtaatg gtaacattat
    14101 ttcagccttg caggatatgc aggagttggc tccccatttt atcagtgtaa ctgccagcaa
    14161 taataaattt aatatcaagg aaacgacggt tcgtttggct gactttatcc aaaatgactt
    14221 ggcgattccg accattgccc acttgccagc tatttatcta actaaggaca aggttgctga
    14281 aactattgct gacttggaca aagttggggt tcagaaaatc ttggctcttc gtggggatat
    14341 tattccagac gtagaaccac aaaaggattt ccgctatgca accgacttga ttgagtttat
    14401 caaggaacaa gcccctcact ttgatattat tggagcttgc tatccagaag ggcatccaga
    14461 ttcgccaaat cagatttcag atattcaaaa tcttaagaag aaagtggatg caggctgttc
    14521 gagcctcgta actcagctct tctttgacaa tgagcgcttc tatgattttc aggacaagtg
    14581 tatcttggct gggattgatg ttcctattca tgcaggaatt atgccaattc tgaatcgaaa
    14641 tcaggctctc cgactcttga agacttgtga gaatatccat cttccacgca aatttaaagc
    14701 catcttagac aagtatgagc atgaccctga gtcgctcaga gcagcaggac ttgcctatgc
    14761 agtggaccaa atcgtggact tggtaactca ggatgttgcc ggtgtgcatc tctatacgat
    14821 gaataatgct gatacagcaa aatacatcca tcaagcaacc catgccttgt ttaatcacca
    14881 gtctctagga taataaaagc aaaccattct tctcaggtga ggggaatggt tcctttttaa
    14941 tggtaaagac ctcacttttt aagaaaaata tgataaaata gattctgtac gtacttgata
    15001 caaagatgaa ggtattaaat aatacaatgc atttaaactg taagatttaa cgacacgagt
    15061 gagtcaaatc gatgttattt gacgaaagag ttagtaaagc atttagctaa tcgcccgata
    15121 gcgattagcg tgaaaggttt agatacttta atattaaacc tttctaatga tgtatcttga
    15181 aaactgaaca cgcctacaac tctgtggaaa aagataaatc tgcctaggag cagtcgctcc
    15241 gtcgttcgat ttcctatctt cctttgagtt gcttgacggc ttggtatctt gatgacttga
    15301 attttggtct catttcttag gaaaaaagat aagcttccta gcactcgtcg agtgcgacgt
    15361 caccttccta tttttctaca gaaatgttcg gcaagccgaa ccgtccaaaa tatcttgtgt
    15421 aattgaacac ggccgaaaag ctgtgtaaaa aagataaact gtcttgtctt catcgaagac
    15481 ttcgtcagtt tcctattttt actttgcttt tgacgtcctt ggtatcttga tctttgtagg
    15541 caaggcgtat aatttcatca atccaaaggg gattaaaatg gcaaaacaag tgtttcaaac
    15601 gacttttgcg ggtcgtgagt taattgtaga gactggtcag gttgctaagc aagcaaatgg
    15661 ctctgttgtc gtacgttacg gtgagtcaac tgtcttgact gctgccgtta tgtctaagaa
    15721 aatggcaact ggggattttt tcccactcca agtcaactac gaagaaaaaa tgtatgcggc
    15781 tgggaagttt cctggtggct ttatgaaacg tgaaggacgt ccttcaacag atgcgacctt
    15841 gacagcgcgt ttgattgacc gtccgattcg tcctatgttt gcggaaggtt tccgtaatga
    15901 agtccaagtc atcaatacag tgctttctta tgatgaaaat gcatctgcac caatggctgc
    15961 tatgtttggt tcatctttgg cactgtctat ttcagatatt ccatttgacg gaccaattgc
    16021 tggggtacaa gtgggatatg tagatgacca aatcatcatc aacccaagtc aagaacaagc
    16081 agagcaatct cttcttgaat tgacagtagc tggaactaag cacgctatca acatggtaga
    16141 gtctggtgcc aaagaattgt cagaagaaat catgttggaa gcgcttctta aagggcacga
    16201 agctgtcaaa gaattgattg ccttccaaga agaaatcgtt gctgctgtcg gtaaagaaaa
    16261 agcagaagtg gaattgcttc acgtggatgc tgaattgcaa gctgaaatca ttgcagccta
    16321 caacagtgac ctccaaaagg cagttcaagt agaagagaaa ttggcccgtg aagctgcaac
    16381 tcaagcagtg aaagaccaag tgactgccgt ttacgaagaa aaatatgcgg accacgaaga
    16441 atttgaccgt attatgcgtg atgtggctga aatcttggaa caaatggaac acgcagaagt
    16501 gcgacgttta attacagaag acaaggtgcg tcctgatggt cgtaaggtcg atgaaatccg
    16561 tcctttggat gcggttgttg acttccttcc tcgtgtacat ggttcaggtc tctttactcg
    16621 tgggcaaact caagctcttt cagtcttgac cttggctccg atgggagaaa ctcaaatcat
    16681 tgatggtttg gatccagagt acaagaaacg ctttatgcac cactataact tccctcaata
    16741 ttctgtaggg gaaacaggtc gttacggtgc gccaggtcgt cgtgaaatcg gtcacggtgc
    16801 ccttggtgag cgtgctcttg ctcaagtctt gccaagcttg gaagaattcc catacgctat
    16861 ccgtctagta gcagaagttt tggaatcaaa cggttcttca tctcaagctt ctatctgtgc
    16921 gggaactctt gcccttatgg ctggtggtgt gccaatcaag gcgccagtag ctggtattgc
    16981 tatgggactt atctcagatg gaaataacta cacagtattg acagatatcc aaggtttgga
    17041 agatcacttt ggagatatgg acttcaaggt tgcaggtact cgtgatggga ttacagccct
    17101 tcaaatggat atcaagattc aagggattac tgcagaaatc ttgacggagg ctcttgctca
    17161 agccaagaaa gcgcgttttg aaatccttga tgtcattgaa gcaaccattc cagaagttcg
    17221 tctagaattg gctccaactg ctccgaaaat tgatacgatc aagattgatg tggacaagat
    17281 taagattgtc atcggtaagg gtggagaaac catcgacaag attatcgctg aaacaggtgt
    17341 taagattgat atagacgaag aaggaaatgt gtctatctac tctagtgacc aagatgctat
    17401 taaccgtgcc aaagaaatta ttgctggttt ggttcgtgaa gccaaagtgg atgaagttta
    17461 ccgtgctaaa gtcgttcgta tcgagaaatt tggtgccttt gttaacctct ttgataagac
    17521 agatgccctt gttcatatct ctgagatggc ttggactcgt accaatcgtg tagaggattt
    17581 ggtagaaatc ggggatgaag ttgatgttaa ggttatcaag attgatgaaa aaggccgtat
    17641 cgatgcctct atgaaggctc ttctacctcg tccgccaaaa cctgagcatg atgaaaaagg
    17701 tgaaaagtct gagcgtcctc accgcccacg tcatcacaag gatcacaaac ctaagaaaga
    17761 atttacagaa acaccaaaag attcagaata agaaaaggag aaatgtatgg ggtggtggcg
    17821 cgaaaccatt gatatcgtaa aagaaaatga tccagcggcc cgcaccactt tggaggtttt
    17881 gctgacttat ccaggtgtca aggccttggc ggcccaccgt ctctcgcatt ttatctggaa
    17941 gcacggcttc aaactcttag ctcgtatgca cagtcagttt tggcgctttt ggactcagat
    18001 tgagattcat ccaggagccc agattgattc aggtgtcttt attgaccatg gttctggtct
    18061 ggtgattgga gagacagcga ttgttgaaaa aggcgttctt ctctatcacg gagtgactct
    18121 tgggggaaca gggaaagact gtggcaaacg ccatccgact gtacgaaagg gagccctcat
    18181 atcagcccat gcccaagtta tcggacctgt ggaaattggt gaaaatgcca aggtcggtgc
    18241 tgcagcagtt gtcgtagcag atgtacctag tgatgtgacg gttgtcggta ttccggccaa
    18301 gattgtccgt cttcatggta agaaagatga gcctgtcatt cacgaagtcg aagaaaaacg
    18361 agagtattat gtcaataaac tcgagcaggc taaagatgcc agtcacagat cgtctggttt
    18421 gtagaggata cctatatgat tcaagtaaga aacaagttaa gccaagagga gctatctgag
    18481 gcgaaaaaag taattaactg ttgccaaaac tatgacggta cctatcgcga tccctatctc
    18541 tctaacatgc ttaattttga cccaaacatg cccgcctttt tcctttatta tgaaaaaggc
    18601 gaacttgttg gtttattaac tgtctatgca gatgaccaag atgtagaagt gacgatactg
    18661 gttcatccag gtcatcgccg tcaggggatt gcgcgtgcat tgtttactag ttttgagaga
    18721 gaaacagctt ctttccccat tcgatcagtc acttttcaga cagaacgtat ttttttagag
    18781 aatcatcctg actttgccag taactgggga ctaatcgagg atgaagagac agaaacttgg
    18841 ttaggtaagg atagaagacc ttatccgtta gcaaatgttt cccatattga agttttgtta
    18901 gcagatagtt cgtatcagga tcaaattagt caattaaaat ttcaggcatt ttcagaggaa
    18961 catgaatcga gagaagttgt ggatagatat gtcgctgaag ctctgaagga tccagaaagc
    19021 cgactatata ttttgttaaa agacggtcag gttattggga cttgcacggt agatttatcg
    19081 actaatacga attacttcta cggtttagca atatcggaac ctgaacgtgg gaaaggctat
    19141 ggaagctact tagcaaaatc cctcgtcaac caactaattg agcaaaatga caaggaattt
    19201 cagattgcag tggaagatag caatgtaggt gccaaacgtt tgtatgaaaa aattggcttt
    19261 gtcaaacaga ctcaggtggt ttatctgaat gagaaaggag caagggattc cgaagtgtag
    19321 agatattcgg actgaaattt acttgaactt ttagtgatga aactaattgt tcttggattt
    19381 cagctttctt gattatgatt tatgattaaa atctatgaca ccatgtctcg tgatttgcga
    19441 gaatttgtcc cgattgagga cggcaagatc aagatgtatg tttgtgggcc aacggtgtac
    19501 aactatattc atgtagggaa tgctcgttca acggtagctt ttgataccat tcgtcgctat
    19561 tttgagtatc gtgggtacga ggttgcctat atttccaatt ttacggatgt ggatgataag
    19621 attatcaacc gtgccaggga agaaggcatc acgcctcagg aggttgcgga taagtacatc
    19681 gctgcctttc gtgaggatgt gacggccttg ggcgtgaaac ctgcgactcg ccatccgcgt
    19741 gtagtggagt ttatggcaga catcatccgt tttgtggaag gcttgatcga gaaaggcttt
    19801 gcctatgaga gtcaagggga tgtctatttc cgtgtagaaa aatcccacaa ctatgctaaa
    19861 ttggctaata aaaccttgga agatttggag ctaggtgctt caggtcgtac cgatgaagaa
    19921 acggctcgta aggaaaatcc tgtagacttt gctctatgga aatcttccaa accaggtgag
    19981 atttcttggg atagtccttg gggacctgga cgtccgggtt ggcatattga gtgttcagtc
    20041 atgtcgacag agattttagg tgataccatt gatattcacg gtggtggagc tgacctagag
    20101 tttccacacc acaccaatga aattgcccaa tctgaagcta aaacaggcaa ggcttttgct
    20161 aactactgga tgcacaatgg ctttgtcaat atcgacaatg tcaaaatgtc taagtccttg
    20221 ggtaacttca ttacggtaca cgatgccctt aaaactcttg atgggcaagt acttcgtttc
    20281 ttctttgcga cccagcacta ccgtaagcct atcaacttca cggaaaaggc agttcgcgat
    20341 gccgagacca atctcaagta tctgaagaat acttacgaac aaccatttac aggaaacgtg
    20401 gatgcccaag agttacaaaa ctttaaagat aagtttgtag cagctatgga tgaagatttt
    20461 aatgctgcca acggtatcac agttgtcttt gaaatggcca aatggatcaa ctcagggaac
    20521 tatgatgcaa gtgtcaagca agctcttgca gatatgttag aaatttttgg aattgtcttt
    20581 gttgaggaag ttttggatgc agagattgaa gacttgattc aaaaacgcca agaggcgcgt
    20641 gccaatcgtg actttgcgac agcagaccaa atccgtgacc aattggttac tcaaggaatt
    20701 aagctccttg ataccaagga tggagtgagg tggacacgtg attgatgtca atctcattaa
    20761 cgggattgcg ctagcctttg agggagatgc ggtgtattct atgtatattc gccgccacct
    20821 catcctcaaa ggtatgacca agcccaataa actccaccaa gaggcgacca agtacgtgtc
    20881 agccaaggct caagctcgcc tgatttctct catgttggag gagcagatcc taacggaaaa
    20941 agaagaagaa atctacaaac gtggccgcaa taccaatagt cacacaaagg ctaaaaatgc
    21001 agatgtcgtg acttatcgta tgtccacggg atttgaagca gttatgggct atctccatat
    21061 gactgagaat ctggaacgtc ttgagagttt ggtttcatgg tgcatccaaa aagtggaggg
    21121 ctagaacatg agggcaaaag aactacaaga ctggtttcct gaggctcgga tttcagacca
    21181 accagtagag aaagagggct atctcacgct tcctttagct tctcagcagt ggattttgct
    21241 ggaggaagct gggctcagcg agcgtgaaaa gcagttggtt gcccttttga cccagcagga
    21301 gcaggctcgt tcgctaaacc cttggtattc ctatctggtt gaaggcaagg gacaggcacc
    21361 gcaagttttt aaaaagattc agttggttta ttgccatctt tcttattttc agcaggaaaa
    21421 tctggcttct tggctagata tgatgcggac tctttttccg aattgtcaga cagtgttaca
    21481 ggtcggagct caggattatg ttttcgtgct tcaacaagac aaatacactt ctgtaagaga
    21541 tattttaagt gatatgattg aagcagttga gtatgacttt ggacttcgtc tttctatcat
    21601 gttgggtcag gtttggtctc agacaggaca tcaagcccta tcagacttaa tcaaagctga
    21661 gcgggatttg ttcaagacat ggtggcgtca gggtcaccaa ggtgttcata ctttttctca
    21721 gctctatctt tggagtatgg gagaaagact cgtggacttg aagccaatta aagaatgtct
    21781 acaccagatg attttggatc aagatcagat tcaggaaatc attctctctc tttgggaaaa
    21841 tagtgctgtt ctcactaaaa cagcccagca actctatctg caccgcaatt ctctccaata
    21901 caagattgat aaatgggaag agttgacagg gcttcagttg aaagagttga ccgacctgac
    21961 cttgtgttat caattgattt taggttcttt gtcaactata gttggtttgt aaagaag
//
LOCUS       DAVBDR010000033        21433 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.033, whole genome shotgun sequence.
ACCESSION   DAVBDR010000033 DAVBDR010000000
VERSION     DAVBDR010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21433)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21433)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21433
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.033"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            66..287
                     /locus_tag="VQ540_001282"
     CDS             66..287
                     /locus_tag="VQ540_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET2545086.1"
                     /translation="MYRRLRDLREDHDLTQKQIAKILSFTNSAYAKIERGEHTLTADV
                     LVTLSNFYDVSTDYLLELTDFPDKIRFRK"
     gene            804..1043
                     /locus_tag="VQ540_001283"
                     /pseudo
     CDS             804..1043
                     /locus_tag="VQ540_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558195.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            1187..2416
                     /locus_tag="VQ540_001284"
     CDS             1187..2416
                     /locus_tag="VQ540_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HET2545087.1"
                     /translation="MKISKRHLLNYSILIPYLLLSILGLIVVYSTTSAILIEEGKSAL
                     QLVRNQGIFWIVSLILIALIYKLRLDFLRNERLIILVILIEMLLLFLARFIGISVNGA
                     YGWISVAGVTIQPAEYLKIIIIWYLAHRFSKQQEEIATYDFQVLTQNQWLPRAFNDWR
                     FVLLVLIGSLGIFPDLGNATILVLVSLIMYTVSGIAYRWFSTILALVSAASVFVLTTI
                     SLIGVETFSKIPVFGYVAKRFSAFFNPFADRADAGHQLANSYFAMVNGGWFGLGLGNS
                     IEKRGYLPEAHTDFVFSIVIEEFGFVGASLILALLFFMILRIILVGIRAENPFNAMVA
                     LGVGGMMLVQVFVNIGGISGLIPSTGVTFPFLSQGGNSLLVLSVAVAFVLNIDASEKR
                     AKLYRELENQPMNLLLK"
     gene            2436..5132
                     /gene="ppc"
                     /locus_tag="VQ540_001285"
     CDS             2436..5132
                     /gene="ppc"
                     /locus_tag="VQ540_001285"
                     /EC_number="4.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxylase"
                     /protein_id="HET2545088.1"
                     /translation="MSLQKLENSSNKSVVQEEVLILTELLEDITKNMLAPETFEKIIQ
                     LKELSTQEDYQGLNRLVTSLSNDEMVYISRYFSILPLLINISEDVDLAYEINHQNNID
                     QDYLGKLSTTIKLVAEKENAVEILEHLNVVPVLTAHPTQVQRKSMLDLTNHIHSLLRK
                     YRDVKLGLINKDKWYNDLRRYIEIIMQTDMIREKKLKVTNEITNAMEYYNSSFLKAVP
                     HLTTEYKRLAQAHGLNLKQAKPITMGMWIGGDRDGNPFVTAKTLKQSALTQCEVIMNY
                     YDKKIYQLYREFSLSTSIVNVSKQVREMARQSKDNSIYREKELYRRALFDIQSKIQAT
                     KTYLIEDEEVGTRYETANDFYKDLIAIRDSLLENKGESLISGDFVELLQAVEIFGFYL
                     ASIDMRQDSSVYEACVAELLKSAGIHSRYSELSEEEKCDLLLKELEEDPRILSATHAE
                     KSELLAKELAIFKTARVLKDKLGDDVIRQTIISHATNLSDMLELAILLKEVGLVDTER
                     ARVQIVPLFETIEDLDHSEETMRKYLSLSLAKKWIDSRNNYQEIMLGYSDSNKDGGYL
                     SSCWTLYKAQQQLTAIGDEFGVKVTFFHGRGGTVGRGGGPTYEAITSQPLKSIKDRIR
                     LTEQGEVIGNKYGNKDAAYYNLEMLVSAAINRMITQKKSDTNTPNRYEAIMDQVVDRS
                     YDIYRDLVFGNEHFYDYFFESSPIKAISSFNIGSRPAARKTITEIGGLRAIPWVFSWS
                     QSRVMFPGWYGVGSSFKEFINKNPENIAILRDMYQNWPFFQSLLSNVDMVLSKSNMNI
                     AFEYAKLCEDEQVKAIYEIILNEWQVTKNVILAIEGHDELLADNPYLKASLDYRMPYF
                     NILNYIQLELIKRQRRGELSSDQERLIHITINGIATGLRNSG"
     misc_binding    5215..5432
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            5545..6549
                     /locus_tag="VQ540_001286"
     CDS             5545..6549
                     /locus_tag="VQ540_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HET2545089.1"
                     /translation="MKNKRLIGIIAALAVLVAGSLIYSSMNKSEAQNNKDEKKITKIG
                     VLQFVSHPSLDLIYKGIQDGLAEEGYKDDQVKIDFMNSEGDQSKVATMSKQLVANGND
                     LVVGIATPAAQGLASATKDLPVIMAAITDPIGANLVKDLKKPGGNVTGVSDHNPAQQQ
                     IELIKALTPNVKTIGALYSSSEDNSKTQVEEFKAYAEKAGLTVETFAVPSTNEIASTV
                     TVMTIKVDAIWVPIDNTIASGFPTVVSSNQSSKKPIYPSATAMVEVGGLASVVIDQHD
                     LGVATGKMIVQVLKGAKPADTPVNVFSTGKSVINKKIAQELGITIPESVLKEAGQVIE
                     "
     gene            6618..7484
                     /locus_tag="VQ540_001287"
     CDS             6618..7484
                     /locus_tag="VQ540_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2545090.1"
                     /translation="MIVSIISQGFVWAILGLGIFMTFRILNFPDMTTEGSFPLGGAVA
                     VTLITKGVNPFLATLVAVGAGCLAGMAAGLLYTKGKIPTLLSGILVMTSCHSIMLLIM
                     GRANLGLLGTKQIQDVLPFDSDLNQLLTGLIFVSIVIALMLFFLDTKLGQAYIATGDN
                     PDMARSFGIHTGRMELMGLVLSNGVIALAGALIAQQEGYADVSRGIGVIVVGLASLII
                     GEVIFKSLSLAERLVTIVVGSIAYQFLVWAVIALGFNTSYLRLYSALILAVCLMIPTF
                     KQTILKGAKLSK"
     gene            7481..8239
                     /locus_tag="VQ540_001288"
     CDS             7481..8239
                     /locus_tag="VQ540_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2545091.1"
                     /translation="MTAIVELKNATKIVKNGFDEEKIILNDVSLEIFERDFITILGGN
                     GAGKSTLFNTIAGTLSLTSGTIRILGEDLTKFSPEKRAKYLSRVFQDPKMGTAPRMTV
                     AENLLIAKFRGEKRGLLPRRLTSYKDEFQATIEKVGNGLEKHLNTPIEFLSGGQRQAL
                     SLLMATLKRPELLLLDEHTAALDPKTSVALMELTDEFVKKDQLTALMITHHMEDALKY
                     GNRLIVMKEGRIIQDLNQEEKAKMKISDYYQLFE"
     gene            8329..10089
                     /gene="dnaG"
                     /locus_tag="VQ540_001289"
     CDS             8329..10089
                     /gene="dnaG"
                     /locus_tag="VQ540_001289"
                     /EC_number="2.7.7.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000227865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HET2545092.1"
                     /translation="MVDKQVIEEIKNNANIVEVIGDVISLQKAGRNYLGLCPFHGEKT
                     PSFNVVEDKQFYHCFGCGRSGDVFKFIEEYQGVTFMEAVQILGQRVGIEVEKPLYSEQ
                     KPASPHQALYDMHEDAAKFYHAILMTTTMGEEARNYLYQRGLTDEVLKHFWIGLAPPE
                     RNYLYQRLSDQYREEDLLDSGLFYLSDANQFVDTFHNRIMFPLTNDQGKVIAFSGRIW
                     QKTDSQTSKYKNSRSTAIFNKSYELYHMDRAKKSSGKTSEIYLMEGFMDVIAAYRAGI
                     ENAVASMGTALSREHVEHLKRLTKKLVLVYDGDKAGQAAILKALDEIGDMPVQIVSMP
                     DNLDPDEYLQKNGPEDLAYLLTKTRISPIEFYIHQYKPENSENLQAQIEFIEKIAPLI
                     VQEKSIAAQNSYIHILADSLASFDYTQIEQIVNESRQVQRQNRMERISRPTPITMPVT
                     KQLSAIMRAEAHLLYRMMESPLVLNDYRLREDFAFATPEFQVLYDLLGQYGNLPPEVL
                     AEQTEEVERAWYQVLAQDLPAEISPQELSEVEMTRNKALLNQDNMRIKKKVQEASHVG
                     DTDTALEELERLISQKRRME"
     gene            10092..11201
                     /gene="rpoD"
                     /locus_tag="VQ540_001290"
     CDS             10092..11201
                     /gene="rpoD"
                     /locus_tag="VQ540_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HET2545093.1"
                     /translation="MATKQKEVTTFDVQVAEFIRNHKQKGTATDDEINASLVIPFTLD
                     ADGIEDLLQRIQDAGISITDNEGNPSARVLSNEEEPELSDEDLIGSTSAKVNDPVRMY
                     LKEIGVVPLLTNEEEKELALAVEAGDIEAKQRLAEANLRLVVSIAKRYVGRGMQFLDL
                     IQEGNMGLMKAVDKFDYSKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETINK
                     LVREQRNLLQELGQDPTPEQIAERMDMTPDKVREILKIAQEPVSLETPIGEEDDSHLG
                     DFIEDEVIENPVDYTTRIVLREQLDEILDTLTDREENVLRLRFGLDDGKMRTLEDVGK
                     VFNVTRERIRQIEAKALRKLRQPSRSKPLRDFIED"
     gene            11215..11544
                     /locus_tag="VQ540_001291"
     CDS             11215..11544
                     /locus_tag="VQ540_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HET2545094.1"
                     /translation="MAYTEEQIENIKTRILTALEEVIDPELGIDIVNLGLIYEIRFDG
                     DTGQTEIDMTLTTMGCPLADLLTDQIYDAMIEVPEVTDTEVKLVWYPAWTVEKMSRYA
                     RIALGIK"
     gene            11659..12702
                     /gene="cpoA"
                     /locus_tag="VQ540_001292"
     CDS             11659..12702
                     /gene="cpoA"
                     /locus_tag="VQ540_001292"
                     /EC_number="2.4.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosylglucosyldiacylglycerol synthase"
                     /protein_id="HET2545095.1"
                     /translation="MEKKKLRINMLSSSEKVAGQGVSGAYRELVRLLHRAAKDQLIVT
                     ENLPIEADVTHFHTIDFPYYLSTFQKKRSGRKIGYVHFLPATLEGSLKIPFFLKGIVK
                     RYVFSFYNRMEHLVVVNPMFIEDLVAAGIPREKVTYIPNFVNKEKWHPLPQEEVVRLR
                     TDLGLSDNQFIVVGAGQVQKRKGIDDFIRLAEELPQITFIWAGGFSFGGMTDGYEHYK
                     KIMENPPKNLIFPGIVSPERMRELYALADLFLLPSYNELFPMTILEAASCEAPIMLRD
                     LDLYKVILEGNYRATAGREEMKEAILEYQANPAVLKDLKEKAKNISREYSEEHLLQIW
                     LDFYEKQAALGRK"
     gene            12718..14043
                     /locus_tag="VQ540_001293"
     CDS             12718..14043
                     /locus_tag="VQ540_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HET2545096.1"
                     /translation="MRIGLFTDTYFPQVSGVATSIRTLKTELEKQGHAVFIFTTTDKD
                     VNRYEDWQIIRIPSVPFFAFKDRRFAYRGFSKALEIAKQYQLDIIHTQTEFSLGLLGI
                     WIARELKIPVIHTYHTQYEDYVHYIAKGILIRPSMVKYLVRGFLHDVDGVICPSEIVR
                     DLLSDYKVKVEKRVIPTGIELAKFERPEIKQENLKELRSKLGIQDGEKTLLSLSRISY
                     EKNIQAVLAAFADVLKEEDKVKLVVAGDGPYLNDLKEQAQNLEIQDSVIFTGMIAPSE
                     TALYYKAADFFISASTSETQGLTYLESLASGTPVIAHGNPYLNNLISDKMFGALYYGE
                     HDLAGAILEALIATPDMNEHTLSEKLYEISAENFGKRVHEFYLDAIISNNFQKDLAKD
                     DTVSQRIFRTVLYLPQQVVAVPVKGSRRMLKASKTQLISMRDYWKDHEE"
     gene            14074..14250
                     /locus_tag="VQ540_001294"
     CDS             14074..14250
                     /locus_tag="VQ540_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HET2545097.1"
                     /translation="MRSGRDKKIAGVCAGVAHYLDMDPTIVQVIWGVLTCCYGAGIVA
                     YIILWIIAPVATDY"
     gene            14309..14443
                     /locus_tag="VQ540_001295"
     CDS             14309..14443
                     /locus_tag="VQ540_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HET2545098.1"
                     /translation="MAFGDNGNRKKTMFEKITLFIVIIMLVASLLGIFATAIGALSNL
                     "
     gene            14507..15817
                     /gene="obgE"
                     /locus_tag="VQ540_001296"
     CDS             14507..15817
                     /gene="obgE"
                     /locus_tag="VQ540_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000061643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HET2545099.1"
                     /translation="MSMFLDTAKIKVKAGNGGDGMVAFRREKYVPNGGPWGGDGGRGG
                     NVVFVVDEGLRTLMDFRYNRHFKADSGEKGMTKGMHGRGAEDLRVRVPQGTTVRDAET
                     GKVLTDLIEHGQEFIVAHGGRGGRGNIRFATPKNPAPEISENGEPGQERELQLELKIL
                     ADVGLVGFPSVGKSTLLSVITSAKPKIGAYHFTTIVPNLGMVRTQSGESFAVADLPGL
                     IEGASQGVGLGTQFLRHIERTRVILHIIDMSASEGRDPYEDYLAINKELESYNLRLME
                     RPQIIVANKMDMPESQENLEEFKKKLSENYDEFEELPAIFPISGLTKQGLATLLDATA
                     ELLDKTPEFLLYDESDMEEEAYYGFDEEEKAFEISRDDDATWVLSGEKLMKLFNMTNF
                     DRDESVMKFARQLRGMGVDEALRARGAKDGDLVRIGKFEFEFVD"
     gene            15827..15985
                     /locus_tag="VQ540_001297"
     CDS             15827..15985
                     /locus_tag="VQ540_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2545100.1"
                     /translation="MGDKPISFRDADGNFVSAADVWNEKKLEELFNRLNPNRALRLAR
                     TKKENPSQ"
     gene            17035..18294
                     /locus_tag="VQ540_001298"
     CDS             17035..18294
                     /locus_tag="VQ540_001298"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HET2545101.1"
                     /translation="MRKIVINGGLPLQGEITISGAKNSVVALIPAIILADDVVTLDCV
                     PDISDVASLVEIMELMGATVKRYDDVLEIDPRGVQNIPMPYGKINSLRASYYFYGSLL
                     GRFGEATVGLPGGCDLGPRPIDLHLKAFEAMGATASYEGDNMKLSAKDTGLHGASIYM
                     DTVSVGATINTMIAAVKANGRTIIENAAREPEIIDVATLLNNMGAHIRGAGTNIIIID
                     GVERLHGTRHQVIPDRIEAGTYISLAAAVGKGIRINNVLYEHLEGFIAKLEEMGVRMT
                     VSEDSIFVEEQSNLKAINIKTAPYPGFATDLQQPLTPLLLRANGRGTIVDTIYEKRVN
                     HVFELAKMDADISTTNGHILYTGGRDLRGASVKATDLRAGAALVIAGLMAEGKTEITN
                     IEFILRGYSDIIEKLRNLGADIRLVED"
     gene            18310..18861
                     /locus_tag="VQ540_001299"
     CDS             18310..18861
                     /locus_tag="VQ540_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2545102.1"
                     /translation="MNIWTKLAMFSFFETDRLYLRPFFFSDSQDFREIASNPENLQFI
                     FPTQASLEESQYALANYFMKSPLGVWAICDQKNQQMIGSIKFEKLDEIKKEAELGYFL
                     RKDAWSQGFMTEVVRKICQLSFEEFGLKQLFIITHLENEASQRVALKSGFSLFRQFKG
                     SDRYTRKMRDYLEFRYVKGEFNE"
     gene            18854..20131
                     /locus_tag="VQ540_001300"
     CDS             18854..20131
                     /locus_tag="VQ540_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HET2545103.1"
                     /translation="MSKHQEILSYLEELPVGKRVSVRSISNHLGVSDGTAYRAIKEAE
                     NRGIVETRPRSGTIRVKSQKVAIDRLTFAEIAEVTSSEVLAGQEGLEREFSKFSIGAM
                     TEQNILSYLHDGGLLIVGDRTRIQLLALENENAVLVTGGFQVHDDVLKLANQKGIPVL
                     RSKHDTFTVATMINKALSNVQIKTDILTVEKLYRPSHEYGFLRETDTVKDYLDLVRKN
                     RSSRFPVINQHQVVVGVVTMRDAGDKSPSTTIDKVMSRSLFLVGLSTNIANVSQRMIA
                     EDFEMVPVVRSNQTLLGVVTRRDVMEKMSRSQVSALPTFSEQIGQKLSYHHDEVVITV
                     EPFMLEKNGVLANGVLAEILTHMTQDLVVNSGRNLIIEQMLIYFLQAVQIDDILRIQA
                     RIIHHTRRSAIIDYDIYHGHQIVSKANVTVKIN"
     gene            20147..21007
                     /locus_tag="VQ540_001301"
     CDS             20147..21007
                     /locus_tag="VQ540_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl aminopeptidase"
                     /protein_id="HET2545104.1"
                     /translation="MITLKSAREIEAMDKAGDFLASIHIGLRDLIKPGVDMWEVEEYV
                     RRRCKEENFLPLQIGVDGAMMDYPYATCCSLNDEVAHAFPRHYILKDGDLLKVDMVLG
                     GPIAKSDLNVSKLNFNNVEQMKKYTQSYSGGLADSCWAYAVGTPSEEVKNLMDVTKEA
                     MYKGIEQAVVGNRIGDIGAAIQEYAESRGYGVVRDLVGHGVGPTMHEEPMVPNYGIAG
                     RGLRLREGMVLTIEPMINTGDWEIDTDMKTGWAHKTIDGGLSCQYEHQFVITKDGPVI
                     LTSQGEEGTY"
     gene            21230..21340
                     /locus_tag="VQ540_001302"
                     /pseudo
     CDS             21230..21340
                     /locus_tag="VQ540_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818216.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase"
BASE COUNT         6556 a         3681 c         4810 g         6386 t
ORIGIN      
        1 ccagttagga cactttgaat gatttcttag ttttatatat tatacttttc tcaggagaaa
       61 gctagatgta cagacgtttg agagatttga gggaagatca cgatttgacc caaaaacaaa
      121 tagctaaaat actttcgttt acaaactcag cttatgctaa aattgaacgg ggtgagcata
      181 cgttaacagc agatgtattg gtaactctct caaactttta cgatgtcagt acagactacc
      241 tattggaatt gacagatttt cctgataaaa ttcgctttag aaaataatct cctcaatttc
      301 atagagtgtg aaaatgagga gattttttat ttgttctttg aaaattaaat agtccaaaat
      361 ggtactttcc tcatttgtgg agcaaatttg aatggctcgc catgataaga gcgattttaa
      421 agccatcaat aaaatagagc gatactttat atgccatgat acaaatgata tacaatgata
      481 cttctgaccg ttcaggctgc catcgtaaaa gagcagcaag tgaaattctt atgatgactt
      541 catcagtcat gccacgttga atgtgtgagt ttgttagaga aacgcaatta atcctcaaaa
      601 ggttccccga accttttgag ttccacagac gcatcacgtg gagtgtgtaa gcttgttgct
      661 aaaagcgtaa aaaccttgga acgaaaggaa taatagactt cctgcgaaac aaaaatacaa
      721 tacaataaaa ctatggatga tgaagcaagt aaacaattaa gcgatagccg tttcaagagc
      781 cttgtaggtg ttcagcgcac gagatgttag ctgtgttaaa aacagcttat caacgcaacg
      841 taaacgcgca aaaggtggac gaaaaaccaa attaagccta gacgatctcc tcatggtaac
      901 tattcaatac atgcgagaat agcgcactta tgaacaaatt gcggctgatt ttggcattca
      961 cgaaagcaac ataattagtc ggaggtcaat ggattgaagc aactcttatt caaaatggtt
     1021 ttacgatttc aaattctgcc ttaattctgt aaaaacagta aaattcgaag gattgtaagg
     1081 taagagtttt tttctttctg aaaaaatggt ataatagcaa tcaaaactag aaaataaaac
     1141 ggaatttgga acagatttgt ctgtatccta gtagagtggt gatactatga agattagtaa
     1201 gaggcactta ttaaattatt ccatcttgat tccctacttg cttttatcta ttttgggctt
     1261 gattgtggtc tattcgacca ccagtgctat tttaattgaa gaaggcaaga gcgccttgca
     1321 gttggttcga aaccaaggaa tcttttggat tgttagtttg atactgattg ccttaattta
     1381 taaattgaga ctagattttt tgagaaatga gcgactaatc attttagtta tattaataga
     1441 aatgctttta ttgttcttgg ctcgttttat tggtatttca gtaaacgggg catacggttg
     1501 gatttcggtt gcaggagtaa ctattcagcc agctgagtac ttaaaaatca ttattatttg
     1561 gtatttagct caccgattct ccaaacagca agaagaaata gctacttatg attttcaagt
     1621 tttgactcaa aatcaatggc ttccccgtgc ttttaatgat tggcgattcg ttctcctagt
     1681 tctgattgga agtttgggaa ttttccctga tttaggaaat gcgactattt tagtcttggt
     1741 ttccttgatt atgtatacag ttagtggaat cgcttatcgc tggttttcaa ccattctggc
     1801 gctcgtatct gccgcttctg tctttgtctt gaccactatc agcctaatcg gtgttgagac
     1861 cttttcaaaa attccagtat ttggctatgt agccaaacgc tttagtgcct tttttaatcc
     1921 ttttgccgat cgtgctgatg caggtcacca gttagctaat tcttattttg ccatggtcaa
     1981 tggtggttgg tttggtctag gtcttggaaa ctcgattgaa aaacgaggtt atttgccaga
     2041 agctcataca gactttgtct tttctatcgt gattgaagaa tttggctttg ttggtgccag
     2101 tcttatttta gctctcttgt ttttcatgat tttgcggatt atcttggtcg gtattcgagc
     2161 ggagaatcct ttcaatgcca tggttgcact cggtgtcgga gggatgatgt tggttcaggt
     2221 atttgtcaat atcggaggga tttcgggctt gattccatct acaggagtaa ccttcccctt
     2281 cttatcccag ggtggaaata gtcttctagt cttatcagtg gcagtagcct ttgtcttaaa
     2341 tattgatgcc agtgaaaaac gcgctaagtt gtaccgagaa ttggaaaatc aaccaatgaa
     2401 ccttctgttg aagtaggata aagaaaggat agtttatgtc tcttcaaaaa ttagaaaatt
     2461 ctagtaataa aagtgttgtg caagaagaag tcttgattct aacagaatta ctggaagata
     2521 ttactaaaaa tatgcttgcc ccagagacct ttgaaaaaat aatacagttg aaagaattat
     2581 caacgcagga agattatcaa ggtctaaacc gtctagtgac tagcttatca aatgatgaaa
     2641 tggtctatat ttcacgctat ttctctatct tgcctctttt gattaatatt tcagaggatg
     2701 tggatttagc ttatgaaatc aatcatcaaa ataatattga tcaggactat ttaggtaaat
     2761 tatctacaac gattaaattg gtagcagaaa aggaaaatgc cgttgagatc ctagaacact
     2821 tgaatgttgt tccggttttg acagcccatc caacacaagt gcaacgcaaa agtatgttgg
     2881 atttaacaaa tcatattcat agtcttttgc gtaaataccg tgatgttaag ttggggttga
     2941 tcaataaaga taaatggtac aatgatttgc gtcgttacat cgaaattatc atgcagacag
     3001 acatgattcg tgagaaaaaa ttaaaagtga ctaacgaaat cacgaatgct atggaatatt
     3061 ataacagctc ctttttgaaa gctgtacctc atttgacgac ggagtataag cgcttagcgc
     3121 aagcgcatgg tctgaattta aaacaggcta aaccaatcac catgggtatg tggataggtg
     3181 gtgaccgtga tggaaatcca tttgttacag caaagacctt gaagcagtct gcactcactc
     3241 aatgtgaagt catcatgaac tactatgata aaaagattta ccaactttat cgtgaatttt
     3301 ctctttcaac tagcattgtc aacgtcagca agcaagtcag agaaatggct cgtcaatcca
     3361 aggataactc gatttaccgc gaaaaagagc tttaccgtcg tgccttgttt gatattcaat
     3421 caaaaattca ggcaactaaa acctatctga ttgaggatga agaagttggg actcgttatg
     3481 aaaccgccaa tgatttctac aaggatttga ttgccattcg agattctcta ctagagaata
     3541 agggcgagtc cttgatttca ggtgattttg tggaattatt gcaggcagta gagatatttg
     3601 gtttttacct agcatcaatt gatatgcgac aagactctag cgtctatgaa gcctgtgtgg
     3661 cagaactctt gaaatcagca ggaattcatt ctcgttatag cgagttgagc gaagaagaaa
     3721 agtgtgacct tcttttgaaa gaattagaag aagatccccg aattctttct gcgactcacg
     3781 cagaaaaatc agaattatta gcaaaagaac tagctatttt taagacggct cgtgttttga
     3841 aagataagtt gggagatgat gtcatccgtc agaccatcat ttcacatgca accaaccttt
     3901 ctgatatgct agaattagct attctgttaa aagaagtagg actggtggat acggaaaggg
     3961 cgcgtgttca gattgttccc ctttttgaaa caattgaaga cttggatcat tcagaggaaa
     4021 caatgagaaa atatctttct cttagccttg ccaaaaaatg gattgactca cgaaataact
     4081 accaagaaat catgcttggc tactctgaca gtaataaaga tggcggttac ttgtcatcat
     4141 gttggaccct ctacaaggct caacaacaat tgactgctat tggagatgaa tttggcgtta
     4201 aggttacctt cttccatggt cgtggtggta ctgtcggtcg tggtggtggg ccaacctatg
     4261 aagccattac atctcaaccg ctcaagtcta tcaaggatcg tatccgtttg acggagcagg
     4321 gtgaagtaat tgggaataaa tacggtaaca aagacgccgc ttactataac cttgaaatgc
     4381 tagtatcggc agctattaac cgtatgatta ctcagaagaa gagcgatacc aataccccaa
     4441 atcgttatga agccattatg gatcaagtag tggaccgtag ttacgatatc taccgtgatt
     4501 tggtctttgg taatgagcat ttctatgatt atttcttcga gtcaagtcca atcaaggcta
     4561 tttcaagttt taatattggt tctcgtccag ccgctcgtaa gactattact gaaatcggtg
     4621 gtttgcgtgc catcccttgg gtattctcat ggtcacagag tcgtgttatg ttccctggat
     4681 ggtacggggt tggttcaagc ttcaaggaat ttatcaataa aaatccagag aatattgcta
     4741 tcttacgaga tatgtaccaa aattggcctt tcttccaatc gcttctttca aatgttgata
     4801 tggttttgtc aaaatcaaat atgaatattg cttttgaata tgctaaactt tgtgaagacg
     4861 agcaagttaa ggccatctat gagattattt taaatgaatg gcaagttact aagaacgtta
     4921 tcttggctat tgaaggacat gacgaactct tagctgacaa tccatatcta aaagctagtc
     4981 tggattaccg tatgccttac tttaatattc tcaactatat tcagttagag ttgattaaac
     5041 gccaacgtcg tggagaattg tccagtgatc aagaacgatt gattcatatc accatcaacg
     5101 gaattgcgac aggattgcgt aattcaggtt gataattttc aagagtgaat gctaaaagtg
     5161 aatatcaaaa aaattctaat agactattga caagtagttt aaaaatgata taatttaacc
     5221 attcagaaaa gtaatcatac aaacttttta gagagtctgt ggtagctgaa aacagataag
     5281 tggcgatgat gaaaattggg ctgaatgcta tttagaattt gaaattataa aaattcggta
     5341 agcacacctt acagtgcatc tcgttattgc gagactgagc gatagggaaa ttccctataa
     5401 ttgaggtggt accgcgcatc gacgtcctca cacaagtttt ttgtgtgagg atttttttga
     5461 tggaggttag tatggaaaga aaacgatggc gtcgcttgtt tagataagtg aaatatgtta
     5521 aaggaaataa aaaggagaaa cagaatgaaa aataaacgtt taattggaat tattgctgca
     5581 ttagcagtct tagtagcagg aagcttgatt tattcttcaa tgaataaatc agaagctcag
     5641 aataataagg atgagaagaa aataaccaag attggtgtgc ttcaatttgt gagccatcca
     5701 tcccttgatt tgatttataa agggatccaa gatggacttg cagaagaagg atataaagat
     5761 gatcaagtta aaattgattt tatgaactca gaaggtgatc aaagtaaggt tgcgacaatg
     5821 agtaaacaat tggttgcaaa tgggaatgac cttgtggttg gtattgcaac accagcagcc
     5881 caagggttgg ctagtgcaac aaaagaccta ccagttatca tggccgctat tacagaccca
     5941 attggtgcta acttggttaa agatttgaaa aaaccaggtg gtaacgttac aggggtatct
     6001 gaccacaatc cagctcaaca acaaattgaa ctcatcaagg ctctgacacc gaatgtgaaa
     6061 acaatcggag ctctttactc aagtagcgaa gacaattcaa aaacacaggt tgaagaattt
     6121 aaggcttatg ctgaaaaagc aggtctgaca gtggaaacat ttgcagttcc ttcaacaaat
     6181 gaaattgcct caactgtcac tgttatgact atcaaggtag atgctatttg ggttccaatt
     6241 gataacacca ttgcatcagg atttccaacg gttgtctcta gcaatcaaag ttctaagaaa
     6301 ccaatttatc ccagtgcgac agctatggta gaagtaggtg gtttggcatc agttgtaatt
     6361 gaccaacatg accttggtgt ggcaacaggt aaaatgattg tgcaagtctt gaaaggtgca
     6421 aaaccagccg ataccccagt caatgtcttt tcaactggta agtcagtcat caataaaaaa
     6481 atagcacaag aactaggtat tactattcct gagtctgttc tcaaagaagc aggacaagtc
     6541 atcgaataaa taaggtaggg aggaggagac tcttcccatt ttttaaaaag atgaatatag
     6601 aaaggattaa ataaaatatg attgtttcca ttatttctca aggatttgtc tgggctattc
     6661 taggtctggg aatctttatg acatttagga ttttaaactt tccagatatg acgacagaag
     6721 gttccttccc tcttggggga gctgttgctg tcactttgat aaccaaaggc gtgaacccat
     6781 ttttagcgac acttgttgct gtaggagcag gttgtttggc tggaatggca gcaggccttc
     6841 tttatacaaa agggaagatc ccaaccttgc tctcagggat tttggtgatg acttcttgtc
     6901 actcaatcat gctcttgatt atgggacgtg cgaatttagg cctgcttgga accaagcaaa
     6961 ttcaggatgt tttgcctttt gattcggatt tgaatcaact cttgacaggt ctcatctttg
     7021 tgagcattgt tattgctctc atgctctttt tcttggacac taaactcgga caagcctata
     7081 ttgctacagg ggataatcct gatatggcta gaagtttcgg gattcatact ggacgcatgg
     7141 agctcatggg cttggtctta tcaaatggtg tgattgccct tgcaggtgcc ctcattgctc
     7201 agcaagaagg ctatgccgat gtgtctcgag ggatcggggt tatcgttgtg gggcttgcaa
     7261 gtttgattat tggagaagtt attttcaaga gtttgagctt ggcagagcgt ttggttacta
     7321 tcgttgtagg ttctatcgct tatcaatttt tagtgtgggc agttatcgca cttggcttta
     7381 atacaagtta ccttcgttta tacagtgcct tgattttagc agtctgcctc atgattccaa
     7441 catttaagca aacaatcttg aaaggagcca agttaagcaa atgacagcaa ttgtagaatt
     7501 aaaaaatgca accaaaattg ttaaaaatgg ctttgatgaa gaaaagatta ttttaaatga
     7561 tgtttcctta gaaatttttg aacgggactt tatcacgatt ttgggcggaa atggtgctgg
     7621 aaaatcaacc ctctttaaca ctatagcagg gaccttatca ctaactagtg gaactatccg
     7681 tattttaggt gaagatctca ctaagttttc acccgagaag cgtgccaagt acctgtctcg
     7741 tgtcttccaa gatccaaaga tggggacagc tccccgtatg acggtcgctg aaaatctttt
     7801 aatcgccaag tttcgtggtg agaagcgtgg attgttacca cgacgcttga ctagctataa
     7861 ggatgaattt caggcaacca ttgaaaaagt aggaaatggt cttgagaaac acttgaatac
     7921 accgattgag ttcttatcag gtggacaaag acaggctttg agtctcttga tggcaacctt
     7981 gaagcgacct gaattactcc tgttagatga gcatactgct gccctggatc caaagactag
     8041 tgttgctttg atggaattga cagatgaatt tgttaagaaa gatcagctaa cagcccttat
     8101 gattactcat catatggaag atgctctcaa atacggcaat cgcttgattg tcatgaaaga
     8161 aggacggatt atccaagatt taaaccaaga agaaaaagca aaaatgaaaa tctctgatta
     8221 ttatcaactc tttgaataaa gtagggaaaa tgagtgaaat ggtttacttt ttttctgaaa
     8281 taaagtatac tatataaagt aaactatgat aacatggagg tattgtgtat ggttgacaaa
     8341 caagtcattg aagaaatcaa aaacaatgcc aacattgtgg aagtcatagg agatgtgatt
     8401 tctttacaaa aggcaggacg gaactatcta gggctctgtc cttttcatgg tgaaaaaaca
     8461 ccttctttca acgttgtaga ggacaagcag ttttaccact gttttggttg tggtcgctca
     8521 ggtgatgtct ttaaattcat cgaggagtac caaggggtta cctttatgga ggctgtccaa
     8581 atcttaggtc agcgtgtcgg gattgaggtt gaaaaaccgc tttatagtga acagaagcca
     8641 gcctcgcctc accaagctct ttatgatatg cacgaagatg cggctaaatt ttaccatgct
     8701 attctcatga caacgactat gggcgaagag gccagaaatt acctttatca gcggggtttg
     8761 acagatgaag tgcttaaaca tttttggatt ggtttagcac ctccagaacg aaactatctc
     8821 tatcaacgtt tgtctgatca gtatcgtgaa gaggatttac tggattcagg cctgttttat
     8881 ctctcggatg ccaatcaatt tgtagacacc tttcacaatc gcattatgtt tcccctgaca
     8941 aatgaccaag gaaaggtcat tgccttctca ggtcgtatct ggcaaaaaac ggattcacaa
     9001 acttctaagt ataaaaacag ccgatcgact gcaattttta acaaaagtta cgaattatat
     9061 catatggata gggcaaaaaa atcttctgga aaaactagtg agatttacct gatggaagga
     9121 ttcatggatg ttattgcagc ctatcgggct ggaatcgaaa atgctgtggc gtcgatggga
     9181 acggccttga gtcgagagca tgttgagcat ctgaaaaggt taaccaagaa attggttctt
     9241 gtttacgatg gagataaggc tgggcaagcc gcgatattga aagcattgga tgaaattggt
     9301 gatatgcctg tgcaaatcgt tagcatgcct gataacttgg atcctgatga gtatctacaa
     9361 aaaaatggtc cagaagactt ggcctatcta ttaacaaaaa ctcgtattag tccgattgag
     9421 ttctacattc atcagtacaa acctgaaaac agtgaaaatc tgcaggctca gattgagttt
     9481 attgaaaaaa tagctccctt gattgttcaa gaaaagtcca tcgctgctca aaacagctat
     9541 attcatattt tagctgacag tctggcgtcc tttgattata cccagattga gcagattgtt
     9601 aatgagagtc gtcaggtgca aaggcagaat cgcatggaaa gaatttccag accgacgcca
     9661 atcaccatgc ctgtcaccaa gcagttatcg gctattatga gggcagaagc ccatctactc
     9721 tatcggatga tggaatcccc tcttgttttg aacgattacc gtttgcgaga agactttgca
     9781 tttgctacac ctgaatttca ggtcttatat gacttgcttg gccagtatgg aaatcttcct
     9841 ccagaagttt tagcagagca gacagaggaa gttgaaagag cttggtacca agttttagct
     9901 caggatttgc ctgctgagat atcgccgcag gaacttagtg aagtagagat gactcgaaac
     9961 aaggctctct tgaatcagga caatatgaga atcaaaaaga aggtgcagga agctagccat
    10021 gtaggagata cagatacagc cctagaagaa ttggaacgtt taatttccca aaagagaaga
    10081 atggagtaat aatggcaaca aaacaaaaag aagtaacaac atttgacgta caggtagcag
    10141 aatttatccg taatcataag caaaaaggga cagcaacaga tgatgaaatc aatgcaagtc
    10201 tggttattcc ttttaccttg gacgctgatg ggattgaaga tctcttgcaa cggattcagg
    10261 atgcagggat ttctatcaca gataacgaag gaaatccaag tgcgcgtgtt cttagcaatg
    10321 aagaagaacc agaactcagc gatgaggact tgattggatc aacttctgct aaggtcaatg
    10381 accctgtccg tatgtacttg aaagaaatag gggtcgttcc tctcttgacc aatgaagagg
    10441 agaaagagtt ggcactggct gttgaagctg gcgatatcga agccaaacaa cgtcttgcgg
    10501 aagccaatct tcgtttggtt gtttccattg ccaaacgcta tgtcggtcgt ggcatgcagt
    10561 tccttgactt gattcaagaa ggaaatatgg gcttgatgaa ggcggttgac aagtttgact
    10621 attctaaagg gttcaagttt tcaacttatg caacttggtg gattcgtcag gctatcactc
    10681 gtgctattgc ggaccaagct cgtaccatcc gtatcccagt tcacatggtt gaaactatca
    10741 ataaattggt tcgtgaacag cggaatctcc ttcaagaatt ggggcaagat ccgacaccag
    10801 aacagattgc tgaacgaatg gatatgacac ctgataaggt tcgtgaaatc ttgaagattg
    10861 cccaagaacc agtatctctt gaaactccta tcggtgaaga ggacgatagc caccttggag
    10921 actttatcga agatgaagtg attgaaaatc cagtggatta tacgactcgt atcgtcttgc
    10981 gtgagcaatt ggatgaaatc ttagatactc ttacagaccg tgaagaaaat gttctgcgtc
    11041 tacgttttgg actagatgat ggaaaaatgc gcacacttga agatgtgggg aaagtcttta
    11101 acgtaactcg tgagcgtatc cgtcagattg aagcaaaggc tttgagaaaa ctacgccaac
    11161 caagtcgcag caaaccgctt cgtgatttta ttgaagacta agagtgagga aaatatggct
    11221 tatacagaag agcaaattga aaacatcaaa acacggattt taacagcctt ggaagaagtc
    11281 atcgaccctg agttgggaat cgatattgtc aatcttggtt tgatctatga gattcgtttt
    11341 gacggtgaca cagggcaaac agagattgac atgactttga caactatggg ttgtccctta
    11401 gcagaccttt tgacagacca gatttatgat gctatgatag aggttccaga agtaacggat
    11461 actgaggtta aattagtctg gtatccagcc tggacagttg aaaaaatgag tcgctatgcc
    11521 cgcattgccc taggcattaa gtaaacatat aaaagcatgt gagagactag aggaaaagcg
    11581 aggaaatttc ccctcttttc ctctagtctc tcctttcttt tgctgatttt attcaaagaa
    11641 aatgatataa tagtagttat ggagaaaaag aaattacgca tcaatatgtt gagttcaagt
    11701 gagaaagtag caggacaggg agtttcaggt gcttaccgtg aattagttcg tcttcttcac
    11761 cgtgctgcca aggaccaatt gattgttaca gaaaatcttc caatcgaggc agatgtgact
    11821 cactttcata cgattgattt tccctattat ttatcaacct tccaaaagaa acgctcaggg
    11881 agaaagattg gctatgtgca tttcttgcca gctacacttg aaggaagttt gaaaattcca
    11941 tttttcttaa agggaattgt gaaacgctat gtattttctt tttacaaccg gatggagcac
    12001 ttggttgtgg tcaatcctat gtttattgag gatttggtag cagctggtat tccacgtgaa
    12061 aaagtgacct atattcctaa ctttgtcaac aaggaaaaat ggcatcctct accacaagaa
    12121 gaggtagtca gactgcgcac agatcttggt cttagtgaca atcagtttat cgtagtaggt
    12181 gctgggcaag ttcagaaacg taaagggatt gatgacttta tccgtctggc tgaggaattg
    12241 cctcagatta cctttatctg ggctggtggc ttctcttttg gtggtatgac agatggttat
    12301 gaacactata agaaaattat ggaaaatccc cctaaaaatt tgatttttcc aggcattgta
    12361 tcgccagagc ggatgcgcga attgtatgct ctagcggatc ttttcttgtt gcctagttac
    12421 aatgagctct ttcctatgac tattttagaa gctgcgagtt gtgaggctcc tattatgttg
    12481 cgtgatttag atctctataa ggtgattttg gagggaaatt atcgggcgac agcgggtaga
    12541 gaagagatga aagaggctat tttggaatat caagcaaatc ctgctgtctt aaaagatctc
    12601 aaagaaaagg ctaagaatat ttccagagag tattctgaag agcatctgtt acaaatctgg
    12661 ttggactttt atgagaaaca agccgcttta gggagaaagt aaaaagtgag gtaatctatg
    12721 cgaattggtt tatttacaga tacctatttt cctcaggttt ctggtgttgc gaccagtatt
    12781 cgaaccttga aaacagaact tgaaaagcag ggacatgctg tttttatctt tacgacgaca
    12841 gataaggatg tcaatcgcta cgaagattgg caaattatcc gcattccaag tgttcctttc
    12901 tttgctttta aggatcgtcg ctttgcctac cgaggtttta gcaaggcact tgaaattgct
    12961 aaacagtatc agctagatat tatccatact cagacagaat tttctcttgg cctgttgggg
    13021 atttggattg cgcgtgaatt gaaaattcca gtcatccata cctatcacac ccagtatgaa
    13081 gactatgtcc attatattgc taaggggata ttgatccggc cgagtatggt caagtatctg
    13141 gttagaggtt tcctgcatga tgtggatggg gttatttgcc ctagtgagat tgtccgtgac
    13201 ttgctatctg attataaggt caaggttgaa aaacgggtca ttcctactgg gattgaatta
    13261 gccaagtttg agcgtccgga aatcaagcag gaaaatttga aagaactgcg tagtaaacta
    13321 gggattcaag atggtgaaaa gacgttgctt agtctttcga gaatctccta tgaaaaaaat
    13381 attcaagcag ttttagcagc ctttgctgat gttctgaaag aggaagacaa ggttaaactg
    13441 gtagtagctg gggatggccc ttatctgaat gacctcaaag agcaagccca gaacctagag
    13501 attcaagact cagtcatctt tacagggatg attgctccta gtgagacggc tctttactat
    13561 aaagcggcgg atttcttcat ttcggcatcg acaagcgaaa cgcaaggttt gacctacttg
    13621 gaaagcttag ccagtggaac acctgtcatt gctcacggaa atccttattt gaacaacctc
    13681 atcagtgata aaatgtttgg agccttgtac tatggagaac atgatttggc tggtgctatt
    13741 ttggaagccc tgattgcaac accagacatg aatgagcata ccttatcaga gaaattgtat
    13801 gagatttcag ctgagaactt tgggaaacga gtgcatgagt tttatctgga tgccattatt
    13861 tcaaataact tccagaaaga tttggctaaa gatgatacgg tcagtcagcg tatctttagg
    13921 acagttttgt atcttccgca acaggtggtt gctgtacctg taaaaggatc tagacgcatg
    13981 ttgaaggctt caaaaacaca gttgatcagt atgagagact attggaaaga ccatgaagaa
    14041 tagaaagagg aacagctatg aaaaaaacaa ttaatgagaa gcggtcgtga taaaaagatt
    14101 gcgggtgttt gtgctggggt ggcccattat ctggatatgg atccgactat cgttcaagtc
    14161 atttggggtg ttcttacttg ctgttacgga gctggaattg tagcttacat tattttatgg
    14221 attatcgcac cagtagcaac tgactattga aaactagctc aattcatgct aagataatag
    14281 aaaatagaat gtaacgaagg agagaaaaat ggcatttgga gataatggaa atcgtaaaaa
    14341 aactatgttt gagaaaataa ccttgtttat cgtgattatc atgctagtag caagtttatt
    14401 gggaattttt gcaactgcaa ttggtgccct cagtaatcta taaaatagat tcaagaaaat
    14461 ttagtgactg ggatttccca gccctttttt aaagtgagaa gaaataatga gtatgttttt
    14521 agatacagct aagattaagg tcaaggctgg taatggtggc gatggtatgg ttgcctttcg
    14581 tcgtgaaaaa tatgtcccta atggaggccc ttggggtggt gatggtggtc gtggaggcaa
    14641 tgtggtcttc gttgtagacg aaggactacg taccttgatg gatttccgct acaatcgtca
    14701 tttcaaggct gattctggtg aaaaagggat gaccaaaggg atgcatggtc gtggtgctga
    14761 ggaccttaga gttcgagtac cacaaggtac gactgttcgt gatgcggaga ctggcaaggt
    14821 tttaacagat ttgattgaac atgggcaaga atttatcgtt gcccacggtg gtcgtggtgg
    14881 acgtggaaat attcgtttcg cgacaccaaa aaatcctgca ccggaaatct ctgaaaatgg
    14941 agaaccaggt caggaacgtg agttacaatt ggaactaaaa atcttggcag atgtcggttt
    15001 agtaggattc ccatctgtag ggaagtcaac acttttaagt gttattacct cagctaagcc
    15061 taaaattggt gcctaccact ttaccactat tgtaccaaat ttaggtatgg ttcgcaccca
    15121 atcaggtgaa tcctttgcag tagccgactt gccaggtttg attgaagggg ctagtcaagg
    15181 tgttggtttg ggaactcagt ttctccgtca catcgagcgt acacgtgtta tccttcacat
    15241 cattgatatg tcagctagcg aaggccgtga tccatatgag gattacctag ctatcaataa
    15301 agagctggag tcttacaatc ttcgcctcat ggagcgtcca cagattattg tagctaataa
    15361 gatggacatg cctgagagtc aggaaaatct tgaagaattt aagaaaaaat tgtctgaaaa
    15421 ttatgatgaa tttgaagagt taccagctat cttcccaatt tctggattga ccaagcaagg
    15481 tctggcaaca cttttagatg ctacagctga attgttagac aagacaccag aatttttgct
    15541 ctacgacgag tccgatatgg aagaagaagc ttactatgga tttgacgaag aagaaaaagc
    15601 ctttgaaatt agtcgtgatg acgatgcgac atgggtactt tctggtgaaa aactcatgaa
    15661 actctttaat atgaccaact ttgatcgtga tgaatctgtc atgaaatttg cccgtcagct
    15721 tcgtggtatg ggggttgatg aagcccttcg tgcgcgtgga gctaaagatg gggatttggt
    15781 ccgcattggt aaatttgagt ttgaatttgt agactaggag actggtatgg gagataaacc
    15841 gatatctttc cgagatgcgg atggtaattt tgtttccgcc gcagacgttt ggaatgaaaa
    15901 gaaattggaa gaactattta atcgtctcaa tccaaatcgt gccttgagat tggcacgaac
    15961 taaaaaggaa aatccatctc agtaaagaag ctaaaaaatc ccgtgcctca tcagacacgg
    16021 gattttgtgg tacgacaggc atgtatagca aactgaatct ggaatagcac agcatatctt
    16081 ctaaaatatt gttataaatt gatttgaatt tcaaaattaa attgtttgat tcttatctca
    16141 atttgttata gtatatctga tgtcaaagtt ctcggcgagt caaatagcga ttcccaagcc
    16201 tgactatcgt gaggtagcgg attaaaatgg tctggggata gaccgtttta agtctgacgc
    16261 tggaaataag aattgtcaga agaagggata gcgaaatcgt ggctctacga acaggaacgt
    16321 gataataagg cgtatatagc ggataagagg gcctcaaact ctaaagtcca aaaaggtagt
    16381 cgtaacctat atgcgtaaat cacgagagta attgaattcg tactaagatt ttctattttc
    16441 actgtaacct tttaacgtcc ttatatcttg tatacacgag gaaagatgta cgacttatcc
    16501 cgtgaggtct atcactataa agagaaaacg acagatagaa gtgatcctga gtcacggtta
    16561 tctttaaaat agattgtctg ataggacggt atgtataaaa cgcttctgtg aactgagaga
    16621 agggggagaa gttcttgcta aaatttagtt gaacagccgt attccgatac ttagataaga
    16681 gatctagtct tagctcctac tcagttttag gggataaaaa aggggaaata gcgattcgag
    16741 aaagattata ctcttcgaaa atctcttcaa atcacgtcaa tatcgccttg ccgtatgtgt
    16801 aggatactga ctacgtcagt tccatctaca acctcaaaac agtgttttga gcaacctgcg
    16861 gctagtttcc tagtttgatc tttgattttc attgagtatt agtaattcag ttactaactc
    16921 gtcaactctg atttatccaa taaaattgaa aaggatggaa aaaaggataa atttatgata
    16981 tactttattt tgaagacctt attagaaatc ttgaaagagt attgaaaact tagaatgaga
    17041 aaaattgtta tcaatggtgg attaccactg caaggtgaaa tcactattag tggtgctaaa
    17101 aatagtgtcg ttgccttaat tccagctatt atcttggctg atgatgtggt gactttggat
    17161 tgcgttccag atatttcgga tgtagccagt cttgtcgaaa tcatggaatt gatgggagct
    17221 actgttaagc gttatgacga tgtattggag attgacccaa gaggtgttca aaatattcca
    17281 atgccttatg gtaaaattaa cagtcttcgt gcatcttact atttttatgg gagcctctta
    17341 ggccgttttg gtgaagcgac agttggtcta ccgggaggat gtgatcttgg tcctcgtccg
    17401 attgacttac accttaaggc gtttgaagct atgggtgcca ctgctagcta cgagggagat
    17461 aacatgaagt tatctgctaa agatacagga cttcatggtg caagtattta catggatacg
    17521 gttagtgtgg gagcaacgat taatacgatg attgctgcgg ttaaagcaaa tggtcgtact
    17581 attattgaaa atgcagcccg tgaacctgag attattgatg tagctactct cttgaataat
    17641 atgggtgccc atatccgtgg ggcaggaact aatatcatca ttattgatgg tgttgaaaga
    17701 ttacatggga cacgtcatca ggtgattcca gaccgtattg aagctggaac atatatatct
    17761 ttagctgctg cagttggtaa aggaattcgt ataaataatg ttctttacga acacctggaa
    17821 gggtttattg ctaagttgga agaaatggga gtgagaatga ctgtatctga ggacagcatt
    17881 tttgtcgagg aacagtctaa tttgaaagca atcaatatta agacagctcc ttacccaggc
    17941 tttgcaactg atttgcaaca accgcttacc cctcttttac taagagcgaa tggtcgtggt
    18001 acaattgtcg atacgattta cgaaaaacgt gtaaatcatg tttttgaact agcaaagatg
    18061 gatgcggata tttcgacaac aaatggtcat attttgtaca cgggtggacg tgatttacgt
    18121 ggggccagtg ttaaagcgac cgacttaaga gctggggctg cactagtcat tgctgggctt
    18181 atggctgaag gtaaaactga aattaccaat atcgagttta tcttacgtgg ttattctgat
    18241 attatcgaaa aattacgtaa tttaggagcg gatattagac ttgttgagga ttaaaccgta
    18301 gaggtgttta tgaatatttg gaccaaatta gcaatgtttt ctttttttga aacggatcgc
    18361 ttgtatttgc gtcctttctt ttttagtgat agtcaggact tccgcgagat agcttcaaat
    18421 ccagaaaatc ttcaatttat tttcccaacg caggcaagtc tggaagaaag tcaatatgca
    18481 ctggccaatt actttatgaa gtcccctttg ggagtgtggg caatttgtga ccagaaaaat
    18541 caacaaatga ttggttctat taaatttgag aagttagatg aaatcaaaaa agaagctgag
    18601 cttggctatt ttttgagaaa agatgcttgg tcgcaaggat ttatgacaga ggttgttaga
    18661 aaaatttgtc agctttcttt tgaggaattt ggcttaaaac aattatttat cattacccac
    18721 cttgaaaatg aagctagcca aagagttgct cttaagtctg gatttagttt gttccgtcag
    18781 tttaagggaa gtgatcgtta cacaagaaaa atgcgggatt atcttgaatt tcggtatgta
    18841 aaaggagagt tcaatgagta agcatcagga aattctaagc tatttggagg aattaccagt
    18901 aggtaaaagg gtcagtgttc gtagcatttc gaatcatcta ggagttagtg atggaacagc
    18961 ctatcgagct attaaagaag ctgaaaaccg tggaattgtg gagacccgtc ctagaagtgg
    19021 aacaattcgt gttaaatccc agaaagttgc tatagataga ttaacgtttg ctgaaattgc
    19081 agaagtgact tcttctgagg ttctggctgg gcaagaaggt ttagagagag aatttagtaa
    19141 gttttcaatt ggtgccatga ctgaacaaaa tatcttgtct taccttcatg atggggggct
    19201 cttgattgtc ggagaccgaa cccgtattca gttgctagcc ttggaaaatg aaaatgcagt
    19261 tctggttaca gggggatttc aggttcatga tgatgtgctt aaactggcca atcaaaaagg
    19321 gattcctgtt ctaagaagta agcatgatac ctttaccgtc gctaccatga tcaataaagc
    19381 cttgtcaaat gtccaaatca agactgatat tctgacagtt gagaaacttt atcgccctag
    19441 tcatgagtat ggttttctga gagagacaga tacagttaaa gattatttgg acttggttcg
    19501 taagaatcgt agcagccgtt tccctgttat caatcaacat caggtcgttg ttggcgttgt
    19561 aaccatgaga gacgctggtg ataaatcacc aagcacgaca attgataagg ttatgtctcg
    19621 tagtctattt ttggttggat tatcgacaaa tattgccaat gtgagtcaac ggatgatcgc
    19681 agaagacttt gaaatggtac cagttgttcg aagcaatcaa actttgcttg gcgttgtgac
    19741 gcgacgagat gtcatggaga agatgagccg ttcccaagtt tcggctctac caactttttc
    19801 tgagcagatt ggacaaaagc tctcttatca ccatgatgaa gtagtcatta cagtggaacc
    19861 ctttatgcta gaaaaaaatg gagttttggc taatggtgta ttggcagaaa ttctgaccca
    19921 catgacccaa gatttagttg ttaatagtgg tcgcaatctc attatcgagc agatgctgat
    19981 ctactttttg caggccgttc agatagatga tatattgcgc attcaggcac ggattattca
    20041 tcatacgaga cggtcagcta taattgatta cgatatttat catggtcacc agattgtttc
    20101 aaaagcaaat gtgactgtta aaattaatta gaaactagga gaaaagatga taacattaaa
    20161 atcagctcgt gaaatcgaag ctatggacaa ggctggtgat tttctagcaa gtattcatat
    20221 aggcttacgt gatttgatta agccaggcgt agatatgtgg gaagttgaag aatatgtccg
    20281 ccgtcgttgt aaagaagaaa atttccttcc acttcagatt ggggttgacg gtgccatgat
    20341 ggactatcct tatgctacct gttgctctct taacgatgaa gtggctcacg ctttccctcg
    20401 tcattatatc ttgaaagatg gtgatttgct caaagttgat atggttttgg gaggtcccat
    20461 tgctaaatct gacctaaatg tctcaaaatt aaacttcaac aatgttgaac aaatgaaaaa
    20521 atacactcag agttattctg gtggtttagc agactcatgt tgggcttatg ctgttggtac
    20581 accgtccgaa gaagtcaaaa acttgatgga tgtaaccaaa gaagctatgt acaagggtat
    20641 tgagcaagct gttgttggaa atcgtatcgg tgatatcggt gcggctattc aagaatacgc
    20701 tgaaagtcgt ggttacggtg tagtgcgtga tttggttggt catggtgttg gcccaactat
    20761 gcacgaagaa ccaatggttc ctaactatgg tattgcaggt cgtggactcc gtcttcgtga
    20821 aggaatggtc ttaaccattg aaccaatgat caatacaggc gattgggaaa ttgatacaga
    20881 tatgaaaact ggttgggcgc ataagaccat tgacggtgga ttgtcatgtc agtatgaaca
    20941 ccaatttgtc attacgaaag atggacctgt tatcttgact agccaaggtg aagaaggaac
    21001 ttattaataa aaagtgaaaa gactactgga agtttattat gaaaaaatcc agtagatctt
    21061 ttcataataa aacgcattgt atcaagtgtt aggggctgat atcatgcgtt tttctgcttt
    21121 taagattttt tccaactctg tttgtaagcg catcataaca aagggtctag gattcagggc
    21181 tctcctccta tatactatta gtaaagtaaa actaagggag gatattttag tgtcgcagtc
    21241 tattgttcct gtagagattc cacaatattg tcgttttgat tctaaaaaga gaaatggaat
    21301 tctgtttaat gttcgtattg ccaatcttaa atttaccttt tttagattag acttcctgcg
    21361 aaacaaaaca tggtatagta gttctatgaa tgatgaagca agtaaacaac taactgatgc
    21421 acgatttaag cgt
//
LOCUS       DAVBDR010000034        21312 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.034, whole genome shotgun sequence.
ACCESSION   DAVBDR010000034 DAVBDR010000000
VERSION     DAVBDR010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21312)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21312)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21312
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.034"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            complement(57..176)
                     /locus_tag="VQ540_001303"
     CDS             complement(57..176)
                     /locus_tag="VQ540_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HET2545105.1"
                     /translation="MDFKSFIIGLVVGIFGPYMYNLIRKIFSKFPKKDTDSTP"
     gene            complement(179..409)
                     /gene="blpU"
                     /locus_tag="VQ540_001304"
     CDS             complement(179..409)
                     /gene="blpU"
                     /locus_tag="VQ540_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpU"
                     /protein_id="HET2545106.1"
                     /translation="MDTKMMSQFSVMDTEMLACVEGGGCNWGDFAKAGVGGAAARGLQ
                     LGIKTGTWQGAATGAAGGAILGGVAYAATCWW"
     gene            complement(478..747)
                     /gene="blpJ"
                     /locus_tag="VQ540_001305"
     CDS             complement(478..747)
                     /gene="blpJ"
                     /locus_tag="VQ540_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpJ"
                     /protein_id="HET2545107.1"
                     /translation="MNTKMLSQLEVMDTEMLAKVEGGYSSTDCQNALITGVTTGIITG
                     GTGAGLATLGVAGLAGAFVGAHIGAIGGGLTCLGGMVGDKLGLSW"
     gene            complement(1214..1411)
                     /gene="blpI"
                     /locus_tag="VQ540_001306"
     CDS             complement(1214..1411)
                     /gene="blpI"
                     /locus_tag="VQ540_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpI"
                     /protein_id="HET2545108.1"
                     /translation="MNTKMMEQFSVMDNEELEIVSGGRGNLGSAIGGCIGAVLLAAAT
                     GPITGGAATLICVGSGIMSSL"
     gene            1693..2280
                     /locus_tag="VQ540_001307"
     CDS             1693..2280
                     /locus_tag="VQ540_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase C39"
                     /protein_id="HET2545109.1"
                     /translation="MTSYKRTFVPQIDARDCGVAALASIAKFYGSDFSLAHLRELAKT
                     NKEGTTALGIVKAADEMGFETRPVQADKTLFDMSDVPYPFIVHVNKEGKLQHYYVVYQ
                     TKKDYLIIGDPDPSVKITKMSKERFFYEWTGVAIFLATKPSYQPHKDKKNGLLSKLPS
                     SDFQTKISHCLHCSLKLIGHYYQYRWFLLSPRNLG"
     gene            2273..3862
                     /locus_tag="VQ540_001308"
                     /pseudo
     CDS             2273..3862
                     /locus_tag="VQ540_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864064.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
     gene            3873..5234
                     /locus_tag="VQ540_001309"
     CDS             3873..5234
                     /locus_tag="VQ540_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin secretion accessory protein"
                     /protein_id="HET2545110.1"
                     /translation="MNPNLFRSVEFYQRRYHNYATVLIIPLSLLFTFILIFSLVATKE
                     ITVTSQGEIAPTSVIASIQSTSDNPILANHLVANQVVEKGDLLIKYSETMDESQKTAL
                     ETQLQRLEKQKEGLGILKQSLEKATDLFSGEDEFGYHNTFMNFTKQSHDIELGITKTN
                     TEVSNQANLANSSSSAIEQEITKVQQQIGEYQELRDAIINNRARLPTGNPHQSILNRY
                     LIASQGQTQGTAEEPFLSQINQSIASLESSIASLKIQQAGIGSVATYDNSLATKIEVL
                     RTQFLQTASQQQLTVENQLTELKVQLDQATQRLENNTLTAPSKGIVHLNSEFEGKNRI
                     PTGTEIAQIFPVITDTREVLITYYVSSDYLLLLDKGQTVRLKLEKIGNHGTTIIGQLQ
                     SIDQTPTRTEQGNLFKLTALAKLSNEDSKLIQYGLQGRVTSVTTKKTYFDYFKDKILT
                     HSD"
     gene            5291..5446
                     /gene="blpC"
                     /locus_tag="VQ540_001310"
     CDS             5291..5446
                     /gene="blpC"
                     /locus_tag="VQ540_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system pheromone BlpC"
                     /protein_id="HET2545111.1"
                     /translation="MDKKQNLTSFQELTTTELNQIIGGGWWEDFLYRFNIIEQKNTKG
                     FHQPIQL"
     gene            complement(5490..6830)
                     /locus_tag="VQ540_001311"
     CDS             complement(5490..6830)
                     /locus_tag="VQ540_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET2545112.1"
                     /translation="MNVAWILLYTLVTHGLKIVIFFKVDGISLTFERIFKAFLFKILL
                     AVVFGMLGYMVGNTYLSYFMEPLYGIGLSFLLLRELPKKLLLFYGLFPMILVNLFYRG
                     VSYFVLPFLGQGQVYDDYSFIWLCIIIFNFFISLAFLKWLDYDFTSLRKGILDKDFQK
                     SLTQINWIMGAYYLVIQNLSYFEYEQGIQSTTVRHLILVFYLLFFMGIIKKLDTYLKD
                     KLHERLNQEQDLRYREMERYSRHIEELYKEVRSFRHDYTNLLTSLRLGIEEEDMEQIK
                     EIYDSVLKDSSEKLQDNKYDLGRLVNIRDKALKSLLAGKFLKARDKNIVFNVEVPEEI
                     QVEGMSLLDFLTVVSILCDNAIEASVEACQPHVSIAFLKNGAQETFIIENSIKEEGID
                     ISEIFSFGASSKGEERGVGLYTVMKIVESHPNTSLNTTCQDHVFRQVLTVIHIE"
     gene            complement(6844..7581)
                     /locus_tag="VQ540_001312"
     CDS             complement(6844..7581)
                     /locus_tag="VQ540_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001219153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET2545113.1"
                     /translation="MRIFVLEDDFSQQTRIETTIEKLLKEHHITPSSFEVFGKPDQLL
                     AEVHEKGAHQLFFLDIEIRNEEMKGLEVARKIRDRDPYALIVFVTTHSEFMPLSFRYQ
                     VSALDYIDKALSAEEFESRIETALLYANGQDSKSLAEDCFYFKSKFAQFQYPFKEVYY
                     LETSTRPHRVILYTKTDRLEFTASLEEVLKQEPRLLQCHRSFLINPANVVHLDKKEKL
                     LFFPNGGSCLIARYKVREVSEAINNLH"
     gene            complement(7586..7924)
                     /locus_tag="VQ540_001313"
     CDS             complement(7586..7924)
                     /locus_tag="VQ540_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET2545114.1"
                     /translation="MKHMIIQTQKTVYKVNVDDIYYIQTHPTKAHTVQIVTEEASFNM
                     LQNLSNLENQYGETLMRCHRNCLVNLDKLKSIDFQERILFLGEEGQYAVKYARRRYRE
                     IRQKWLKEGE"
     gene            8201..8530
                     /locus_tag="VQ540_001314"
     CDS             8201..8530
                     /locus_tag="VQ540_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
                     /protein_id="HET2545115.1"
                     /translation="MTDTDPIKRAHTLITDLNKAYQACKQASADDVRFQEQLNSILGF
                     LAKAETVDNRFLIELEKFYQTSSLLMGLSALDPDAPTRAAWRAYDRFHFDQVKTKLIL
                     NENQRAN"
     gene            complement(8698..9747)
                     /locus_tag="VQ540_001315"
     CDS             complement(8698..9747)
                     /locus_tag="VQ540_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2545116.1"
                     /translation="MKDLFLKRKQAFRKECLCYLRYVLNDHFVLFLLVLLGFLAYQYS
                     QLLQHFPENHWPILLFVGITSVLLLLWGGIATYMEAPDKLFLLVGEEAIKLHLKRQTG
                     ISLVFWLFVQTLFLLLFAPLFLAMGYGLPVFLLYVLLLGVGKYFHFRQKASKFFTETG
                     LDWDYVISQESKRKQVLLRFFALFTQVKGISNSVKRRAYLDFILKAVQKVPGKIWQNL
                     YLRSYLRNGDLFALSLRLLLLSVLAQVFIEQAWIATAVVVLFNYLLLFQLLALYHAFD
                     YQYLTQLFPLDKGQKEKGLQEVVRGLTSFVLLVELVVGLITFQEKLALLALLGAGLVL
                     LVLYLPYQVKRQMQD"
     gene            complement(9744..10475)
                     /locus_tag="VQ540_001316"
     CDS             complement(9744..10475)
                     /locus_tag="VQ540_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2545117.1"
                     /translation="MLEIKNLTGGYVHVPVLKDVSFTVESGQLVGLIGLNGAGKSTTI
                     NEIIGLLAPYSGSININGLTLQGDATSYRKQIGYIPETPSLYEELTLREHIETVAMAY
                     GIEQKVAFERVEPLLKMFRLEQKLDWFPVHFSKGMKQKVMIICAFVVDPSLFIVDEPF
                     LGLDPLAISDLIQLLEVEKQKGKSILMSTHVLDSAEKMCDAFVILHKGEVRAKGNLLQ
                     LREAFDMPEASLNDIYLALTKEEDL"
     gene            10543..10953
                     /locus_tag="VQ540_001317"
     CDS             10543..10953
                     /locus_tag="VQ540_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HET2545118.1"
                     /translation="MSDCIFCKIIAGEIPASKVYEDEQVLAFLDISQVTLGHTLVVPK
                     EHYRNLLEMNATSASQLFAQVPKVAQKVMKVTKAAGMNIISNCEEVAGQTVFHTHVHL
                     VPRYSADDDLKIDFIAHEPDFDKLAQVAETIKNA"
     gene            10963..11250
                     /locus_tag="VQ540_001318"
     CDS             10963..11250
                     /locus_tag="VQ540_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2545119.1"
                     /translation="MKLSNLLLFAGAAAGSYLVTKNRQTITDEVLNTTDRVQAIKDDV
                     DIIQNSLQIIDQQKELIKEYQEDLTYKFKVLEKDIQTRLAVIKEMQGTEDK"
     gene            11412..11651
                     /locus_tag="VQ540_001319"
     CDS             11412..11651
                     /locus_tag="VQ540_001319"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2545120.1"
                     /translation="MHHNLGNSYSIKIKKQTRKLGTDCSKHRFKVVDRTDEVSSKHCF
                     EVVDRTDEVSNHTHDKPTLTWFEEIFEEYHSPFHN"
     gene            complement(12001..13137)
                     /gene="dnaJ"
                     /locus_tag="VQ540_001320"
     CDS             complement(12001..13137)
                     /gene="dnaJ"
                     /locus_tag="VQ540_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001066288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HET2545121.1"
                     /translation="MNNTEFYDRLGVSKNASADEIKKAYRKLSKKYHPDINKEPGAED
                     KYKEVQEAYETLSDDQKRAAYDQYGAAGANGGFGGAGGFGGFNGAGGFGGFEDIFSSF
                     FGGGGSSRNPNAPRQGDDLQYRVNLTFEEAIFGTEKEVKYHREAGCRTCNGSGAKPGT
                     SPVTCGRCHGAGVINVDTQTPLGMMRRQVTCDVCHGRGKEIKYPCTTCHGTGHEKQAH
                     SVHVKIPAGVETGQQIRLAGQGEAGFNGGPYGDLYVVVSVEASDKFEREGTTIFYNLN
                     LNFVQAALGDTVDIPTVHGDVELVIPEGTQTGKKFRLRSKGAPSLRGGAVGDQYVTVN
                     VVTPTGLNDRQKVALKEFAAAGDLKVNPKKKGFFDHIKDAFDGE"
     gene            complement(13342..13695)
                     /locus_tag="VQ540_001321"
     CDS             complement(13342..13695)
                     /locus_tag="VQ540_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000115730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2545122.1"
                     /translation="MSVNKNNLSDIADYHEKIKFFEELFNLDYNPTEMLVTVERNGNV
                     IYKEFTEVAVGKSKYDHTSVFKDVMIYFSDHICQELHLYKTQDPHYNKFEFDLAKRSL
                     KITTRDNTTIFISNE"
     gene            complement(13708..15531)
                     /gene="dnaK"
                     /locus_tag="VQ540_001322"
     CDS             complement(13708..15531)
                     /gene="dnaK"
                     /locus_tag="VQ540_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HET2545123.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGTESKIIANPEGNRTTPSVVSFKN
                     GEIIVGDAAKRQAVTNPDTVISIKSKMGTSEKVSANGKEYTPQEISAMILQYLKGYAE
                     DYLGEKVTKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTDK
                     EEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNKLGGDDFDQKIIDHLVAEFKKEN
                     GIDLSTDKMAMQRLKDAAEKAKKDLSGVTSTQISLPFITAGEAGPLHLEMTLTRAKFD
                     DLTRDLVERTKVPVRQALSDAGLSLSEIDEVILVGGSTRIPAVVEAVKAETGKEPNKS
                     VNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTSK
                     SQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDIDK
                     NGIVSVKAKDLGTQKEQTIVIQSNSGLTDEEIDRMMKDAEANAEADKKRKEEVDLRNE
                     VDQAIFATEKTIKETEGKGFDAERDAAQAALDDLKKAQEDNNLDDMKAKLEALNEKAQ
                     GLAVKLYEQAAAAQQAQEGAEGAQATGNAGDDVVDGEFTEK"
     gene            complement(16011..16535)
                     /gene="grpE"
                     /locus_tag="VQ540_001323"
     CDS             complement(16011..16535)
                     /gene="grpE"
                     /locus_tag="VQ540_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000046028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HET2545124.1"
                     /translation="MAQDIKNEEVEEVQEEEVVETAEETTPEKSELDLANERADEFEN
                     KYLRAHAEMQNIQRRANEERQNLQRYRSQDLAKAILPSLDNLERALAVEGLTDDVKKG
                     LGMVQESLIHALKEEGIEEIAADGEFDHNYHMAIQTLPADDEHPVDTIAQVFQKGYKL
                     HDRILRPAMVVVYN"
     gene            complement(16562..17596)
                     /gene="hrcA"
                     /locus_tag="VQ540_001324"
     CDS             complement(16562..17596)
                     /gene="hrcA"
                     /locus_tag="VQ540_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HET2545125.1"
                     /translation="MVTERQQDILNLIIDIFTKTHEPVGSKALQESINSSSATIRNDM
                     AELEKQGLLEKAHTSSGRMPSVAGFQYYVKHSLDFHRLAENEVYEIVKAFDQEFFKLE
                     DILQEAANLLTGLSGCTVVALDVEPSRQRLTAFDIVVLGQHTALAVFTLDESRTVTSQ
                     FLIPRNFLQEDLLKLKSIIQERFLGHTVLDIHYKIRTEIPQIIQRYFTTTDNVIDLFE
                     HIFKEMFNENIVMAGKVNLLNFANLEAYQFFDQPQKVALEIREGLREDQMQNVRVADG
                     QESCLADLAVISSKFLIPYRGVGILAIIGPVNLDYQQLINQVNVVNRVLTMKLTDFYR
                     YLSSNHYEVH"
     gene            complement(17760..18269)
                     /locus_tag="VQ540_001325"
     CDS             complement(17760..18269)
                     /locus_tag="VQ540_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001088691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2812 domain-containing protein"
                     /protein_id="HET2545126.1"
                     /translation="MNSRVEFRIFTIVDLDKEEEYLHEMHLKGWRYRTSRFGLFYFDQ
                     CQPDDVIYRIYDSRFLKKYKHELQDFRDRGWELIGAGSCSILRKSSSDLLPEDQVYMS
                     KGLKWEVMRSRLRSCTTTFLGGLVVCTSLFREDLSMSFFLIFVLYAFLISYLIHGYFR
                     LKRKYRVDE"
     gene            18877..20814
                     /locus_tag="VQ540_001326"
                     /pseudo
     CDS             18877..20814
                     /locus_tag="VQ540_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399214.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
     gene            20812..21312
                     /locus_tag="VQ540_001327"
                     /pseudo
     CDS             20812..21312
                     /locus_tag="VQ540_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819352.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
BASE COUNT         6698 a         4437 c         3832 g         6345 t
ORIGIN      
        1 attaaagaaa ctcccctgta aattaagcta gcaaatacag gggagaaatt tattttttag
       61 ggggtactat ctgtatcctt tttgggaaat tttgaaaata tttttctaat taaattatac
      121 atataaggac caaatatacc aactactaaa ccaataataa aacttttaaa atccataatt
      181 accaccaaca tgttgctgca taggctacac ctccaagtat agctccaccc gcagcaccag
      241 ttgctgcacc ttgccatgtt cctgttttaa tgcctagttg aagacctctt gctgctgctc
      301 ctccaacacc tgctttggca aaatctcccc aattgcatcc gccaccttca acgcaagcaa
      361 gcatttcagt atccataaca gaaaattgtg acatcatttt tgtatccatg acaaatactc
      421 cttttttaaa aaactaaaat aaatcagaat agaatcctca taattttact ataagtctta
      481 ccaacttagt cccaatttat caccaaccat acctcctaag catgttaatc cacccccaat
      541 tgcaccaatg tgtgctccaa caaatgcacc agcaagtcca gctactccta aagtggccaa
      601 acctgctcca gttccaccag ttataattcc cgtagtgact cctgtaatca gtgcattttg
      661 acaatcagtg gagctatacc ccccttcaac tttcgcaagc atttcagtat ccataacctc
      721 taactgtgac aacatttttg tattcatgat gaatacctcc tttttatttt caatttgtta
      781 ccaaagtctt aaattcaata aacaaataga ttttttatag tatctttttg attttcttaa
      841 aaaagtatat acgtctacta tcttcttaaa ggtagcagta cctatttttt agtctaagat
      901 ttcaataatc ttgagtatct aaaatatctt aatttcgtta ttctccttgc aataaaaagt
      961 tttactatac tatttattaa cttgcagaaa gcaaaaaata ttagtaaata atagtttata
     1021 gttaagtttt ttattcctac caatccatca actaagtaaa gcatcaacga ttacataaac
     1081 gattgataat ataattaaaa ttttgctaac tatcttattc tcatcattct tagataactt
     1141 tgatattttg taagtaagta aataagacag taaattaata gcgataataa tactatattt
     1201 aagaatcata atcttacaaa gaggacataa ttcctgaacc tacacaaata agtgttgctg
     1261 ctcccccagt tatcggacca gtcgcagcag ctaatagtac tgctccaata caaccaccga
     1321 ttgcagatcc taaattgcct cttcctccac taactatttc gagttcttca ttatccataa
     1381 cagaaaattg ttccatcatt tttgtattca tgacaaatac tccttttttc tttttttatt
     1441 tttgtcttgt tgtaactttg ataagtttag tatatcatcg ttttttaaaa tttttcatcc
     1501 agatcttgaa ttgtcatcga aacgtcttga attagctttt ttatttcaag ccacctctaa
     1561 atgtttaaaa aaaataattt ctaatcactt ttttaccatt caggaagttt taatgactat
     1621 tcaagatttc ataaaatatg aacttagttt tatgacataa tagacctatc cactatatga
     1681 aaagaattgc caatgacttc ttataaacgt acatttgttc ctcaaataga tgcgagagac
     1741 tgtggtgtcg ctgccttagc ctcgattgct aaattctatg gttcagattt ttctctagct
     1801 cacttgagag aacttgcaaa gaccaataaa gaagggacga ctgctcttgg cattgtaaaa
     1861 gccgctgatg aaatgggctt tgaaacaaga cctgttcaag cagataaaac gctctttgac
     1921 atgagtgatg tcccctatcc atttatcgtt cacgttaaca aagaaggaaa actccaacat
     1981 tactatgttg tctatcaaac aaagaaagac tatctgatta ttggtgatcc tgacccttct
     2041 gtaaaaatca ctaaaatgtc aaaagaacgc tttttctatg aatggactgg agtagctatt
     2101 tttctagcta ccaaacccag ctatcaaccc cataaagata aaaagaatgg tctactaagc
     2161 aagcttcctt cctctgattt tcaaacaaaa atctctcatt gcttacattg ttctctcaag
     2221 cttattggtc actattatca atataggtgg ttcttactat ctccaaggaa tcttggatga
     2281 atacattcca aatcagatga aatcaacttt aggaatcatc tcagttggtc tggttatcac
     2341 ctaggttatc acctatatcc tccaacaagt catgagcttc tccagagatt atctcctaac
     2401 cgttctgagc cagagattaa gcattgatgt gattttatcc tatattcgcc atatttttga
     2461 acttcccatg tctttctttg cgacacgtcg tacaggagaa atcatttcac ggttcacaga
     2521 tgctaactct attatagatg ccttggcttc taccattctt tctctttttc tggatgtttc
     2581 tattctgatt cttgtagggg gagtcttgct ggcacaaaac cctaatctct tcctcctttc
     2641 tcttctttcc attcctatat acatgttcat catcttttct tttatgaaac cttttgaaaa
     2701 aatgaaccat gatgtcatgc aaagtaattc tatggttagc tctgccatta tcgaagatat
     2761 caacgggatt gaaactataa agtcgctcac gagtgaagaa aatcgctatc aaaatataga
     2821 cagcgaattt gtagattatt tggaaaaatc ctttaagctc agtaaatatt ctattttaca
     2881 aacgagttta aagcagggaa caaaattagt tctgaatatc cttatcctat ggtttggcgc
     2941 tcaattagtc atgtcgagta aaatttctat cggtcagctg attaccttta acacactttt
     3001 ttcttacttt acaactccta tggaaaatat tatcaacctc caaaccaaac tcccatctgc
     3061 gaaggtcgct aataaccgtt tgaacgaagt ctatctagtc gaatctgaat ttcaagttca
     3121 agaaaaccct gtccattcac attttttgat gggcgatatt gaatttgatg acctttctta
     3181 taagtatggt tttggacgag ataccttaac agatattaat ctcacgatta aacaaggaga
     3241 taaggttagc ctagttggag ttagtggttc tggtaaaaca actttagcca aaatgattgt
     3301 caatttcttt gaaccctaca aagggcatat ttccatcaat catcaggata ttaaaaacat
     3361 tgataaaaaa gtcttgcgcc gtcatattaa ttacctaccc caacaagcct atatctttaa
     3421 tggctctatc ttggaaaatt taaccttggg cggtaatcat atgattagcc aagaagatat
     3481 tctaagagct tgtgaattag ctgaaatccg tcaagacatt gaaagaatgc ctatgggcta
     3541 tcaaactcag ctctctgatg gagctggtct atcaggagga cagaagcaac gaatagccct
     3601 cgctcgtgct cttttaacta aatctcctgt tttaatacta gacgaagcta ctagcggtct
     3661 tgatgtcttg actgagaaaa aagttataga taatcttatg tccctaactg ataaaaccat
     3721 tctctttgta gcccatcgtc tcagtatagc cgaacgaact aaccgtgtca ttgttcttga
     3781 ccaggggaaa atcattgaag ttggtagtca ccaagagtta atgcaggcgc aaggcttcta
     3841 ccatcatctg ttcaataaat aaggagaatg tcatgaatcc taatcttttt agaagcgtcg
     3901 agttttatca gagacgttac cataactatg cgacagtgtt aattatacct ctttcattac
     3961 tgtttacttt catcttgatt ttctcccttg ttgccacaaa agaaattact gttacttccc
     4021 aaggagaaat cgcccctaca agtgtcattg catccattca gtcaaccagt gataatccta
     4081 tccttgctaa tcatttagtg gcaaatcaag tagttgaaaa aggtgactta ctcatcaaat
     4141 actctgaaac aatggatgag agtcagaaaa ctgccttaga aactcaatta caaagacttg
     4201 agaagcaaaa agaaggactt ggaattttga aacaaagttt agaaaaagcg actgatcttt
     4261 tttctggcga ggatgagttt ggctaccata atacctttat gaattttact aaacaatccc
     4321 atgatattga actgggtatc acaaagacta acaccgaagt ttcaaatcaa gctaatcttg
     4381 ccaatagcag ttcatcagcc atcgaacaag aaattacaaa agttcaacaa caaattggag
     4441 aatatcaaga gttgagagat gctatcataa ataacagagc acgcttacca actggcaatc
     4501 cgcaccagtc aattttaaat cgttatctta tagcctctca aggacaaaca caaggaacgg
     4561 cagaggagcc atttttatct caaattaatc aaagtattgc aagtcttgaa tcatctatcg
     4621 caagcctcaa aattcagcaa gctggtatcg gaagtgtagc aacttatgat aatagtttag
     4681 caaccaaaat tgaagtactc cgcactcagt ttttacaaac agcctcacag caacaactaa
     4741 ccgtggagaa tcaattaaca gaattaaaag tacaactaga tcaagcgaca cagcgcttag
     4801 aaaataatac cttaaccgct ccaagtaaag gtatcgttca tctgaacagc gaatttgaag
     4861 gtaaaaatag aattccaact ggtacagaaa ttgctcaaat attccctgtc atcacagata
     4921 caagagaagt actaatcact tactacgtat catctgacta tctcctctta ctagataaag
     4981 gacaaactgt aagattaaaa ctggagaaga ttggaaatca cggcaccacc atcatcggcc
     5041 aacttcagag tattgatcaa actcctacca gaacagagca aggcaatctc tttaaattaa
     5101 ccgctcttgc aaaactatct aacgaggata gtaaactcat ccaatatggc ttacaaggtc
     5161 gcgtcactag tgtaactaca aagaaaacat attttgatta tttcaaagat aaaattttaa
     5221 cacattctga ttaattttca gataacactc tataactatt tattatctta tcaaaaagga
     5281 gaatcataac atggataaga aacaaaacct aacttcattt caagaactaa caactaccga
     5341 actcaaccaa attataggtg gaggatggtg ggaagatttc ttatatagat ttaatataat
     5401 tgaacaaaaa aatacaaaag gatttcatca gccaatacaa ctataaaaaa acaagaccaa
     5461 gagaacgcac tctcggtctt attttttctt cattctatat gtattacagt aagtacctga
     5521 cgaaaaacgt gatcttggca ggtggtattg agactggtat tgggatgact ttccacaatt
     5581 ttcataacgg tatagagacc aactcctctc tcctcccctt tagaacttgc tccaaaggag
     5641 aagatttcag aaatatcgat tccctcttct ttgatggaat tttcaatgat aaaggtctcc
     5701 tgtgctccat tttttaaaaa ggcaattgaa acatgaggtt gacaggcttc tacactagct
     5761 tcaatagcgt tgtcacaaag gatagacaca acggttagaa aatcaagtag actcatcccc
     5821 tctacctgaa tctcctctgg aacttcgaca ttaaagacaa tgttcttatc tctagctttt
     5881 agaaatttcc ctgctaggag acttttgagg gctttatcac gaatattcac caatcgacca
     5941 aggtcatatt tattgtcctg caatttttca ctagaatcct ttaagaccga gtcgtagatc
     6001 tcttttatct gctccatatc ctcctcttca atgcccagac gtaagctagt caagaggttg
     6061 gtgtagtcat ggcgaaaact ccgtacttcc ttataaagct cctctatatg ccgactatac
     6121 cgctccatct ctctgtagcg caagtcctgc tcttggttca gtctctcatg gagtttgtcc
     6181 ttcaaatagg tatccaattt cttgataatc cccataaaaa agagcaggta aaagactagg
     6241 atgagatggc gaacagtcgt tgattgaatc ccctgttcat attcaaagta agacagattt
     6301 tgtatcacca aatagtaagc ccccattatc cagttaatct gagtcaggga cttttgaaaa
     6361 tctttatcga gaatcccctt tctcaagcta gtgaaatcat agtccaacca tttcaaaaaa
     6421 gctagagaaa tgaagaaatt gaaaattatt atacataacc aaataaatga gtagtcatca
     6481 tatacttgcc cttgtcccaa aaatggaagc acaaaatagg aaacacctct ataaaagaga
     6541 ttcactaata tcattggaaa gagaccataa aagagaagga gttttttagg aagttctctt
     6601 aacaataaga aagataagcc tatgccgtac aagggttcca taaaataaga tagataagta
     6661 tttcctacca tatagccaag cattccaaaa acaacggcca acagtatctt aaaaagaaag
     6721 gccttaaaaa tcctctcaaa agtgagacta attccatcta ccttaaagaa tatgacaatt
     6781 tttaatccgt gagtaacaag tgtatacaac aatatccaag caacattcat aaactctcct
     6841 agctcagtgt aagttattaa tagcctcaga cacttccctg accttataac gcgcgattag
     6901 acaacttcca ccattgggaa agaaaagcag tttttctttc ttatctaaat gcaccacatt
     6961 ggcaggattg atgagaaaag agcgatggca ctgcaagaga cgaggctcct gcttgagaac
     7021 ctcctctaga ctcgctgtaa attccagcct gtctgtcttg gtatagagaa taacacgatg
     7081 gggtcttgtg gacgtttcga gatagtaaac ctctttaaaa ggatactgga attgagcaaa
     7141 ttttgattta aagtaaaagc aatcttccgc tagactttta ctgtcttgac cattggcata
     7201 gaggagggct gtctcgatac gagattcaaa ctcctctgcc gaaagggcct tatcaatata
     7261 gtccagagca gacacttggt agcgaaagga caggggcata aactccgagt gagtcgtcac
     7321 aaagacaatc agggcatacg gatcccgatc ccgaatcttt ctagccactt ccagaccctt
     7381 catctcctca tttcgaatct caatatccaa aaagaatagc tgatgggccc ccttctcatg
     7441 cacctctgcc agcagttggt ctggcttgcc aaatacctca aaagagctgg gagtgatatg
     7501 atgttccttc aagagtttct caatcgtcgt ttcaatccta gtctgttggg aaaaatcatc
     7561 ctctaaaaca aatattctca tcttcttact ctccctcttt caaccatttt tgacgaattt
     7621 ctctatagcg acgtctggca tacttgacag cgtattgacc ttcttctccg agaaaaagga
     7681 ttctttcttg aaaatcaatc gattttaatt tatcaagatt aaccaaacaa tttcgatgac
     7741 atctcatcaa ggtttcccca tattggttct caagattact taaattttga agcatattaa
     7801 aactagcttc ttctgtaaca atctgtacgg tatgggcttt agttggatgt gtttggatat
     7861 agtagatatc gtcgacgttt actttataga ctgttttctg cgtctgaata atcatatgtt
     7921 tcattggatt ctcctcctaa gaaaagaata acagaaaagt tctagcccaa gcccacccaa
     7981 tcctaaacag tctttgaaag ctcctaaaag gattattttt ctacaacatc atgatgagct
     8041 tacaactatt ttatcataaa attcactcag cgcaattcaa gacatttcaa tgacaattaa
     8101 agatttgaat aaaaaaaaag aattaaaaat gataaactaa cagtatcaaa acacagttgc
     8161 cagaagtaag actggcaccc agattaaagg aggcattccc atgacagata cagaccccat
     8221 caaaagagct catactttga ttactgactt aaacaaagcc taccaagcat gcaaacaggc
     8281 aagcgctgac gacgtccgct ttcaggagca attaaactct attcttggtt ttttagccaa
     8341 ggctgaaaca gtggataatc gattcttgat tgaactagaa aaattttacc agacttccag
     8401 tcttctcatg ggactcagcg ctcttgatcc agatgctcca actcgcgccg cttggcgggc
     8461 ctatgaccgc ttccactttg accaagtcaa gaccaagtta atactcaatg aaaatcaaag
     8521 agcaaactag gaagctagcc gcaagctgta cttgagtacg gtaaggcgac gctgacgtgg
     8581 tttgaagaga ttttcgaaga gtataagtct ctacggacca accattatcc tgtagtaaca
     8641 aaaaagaagc tgagacagac tgaactcaac ttctttttta gtgtcgtatc agcaatgtta
     8701 gtcctgcatc tgacgtttta cctgataagg caaatacaag actagtaaaa ccaaaccagc
     8761 tcctagtaag gctagaaggg ccagtttttc ttggaaggta atcaacccaa caactaattc
     8821 cacaagtaaa acaaaactgg tcaatcctcg aactacctcc tgtaagcctt tttccttttg
     8881 ccccttgtcc agcggaaaga gttgggtcaa atactggtag tcaaaggcat gatagagggc
     8941 cagcaactgg aagagcaaga ggtagttaaa gagaactacc actgctgtcg caatccaagc
     9001 ttgctcgata aaaacctgcg ccagtacgga aagtaataga agacgaagac tgagagcaaa
     9061 gaggtcgcca tttcgcagat aagaacgcag atagagattt tgccaaatct tcccaggcac
     9121 cttctgaaca gcctttaaga taaagtccag ataggcacga cgcttaacgc tgtttgaaat
     9181 tcccttgacc tgcgtaaaga gggcaaagaa acgaagcaag acttgcttac gcttgctttc
     9241 ttgagaaata acatagtccc agtccagtcc agtttcagta aaaaatttgc tggccttttg
     9301 acgaaagtgg aaatattttc ctacccccaa taaaagcaca tatagcagaa aaactggcaa
     9361 gccataaccc attgctaaaa ataaaggcgc aaataacagc aagaaaaggg tctgtacaaa
     9421 gagccaaaag actagggaaa tgccagtttg acgcttgaga tggagcttga ttgcctcttc
     9481 tccaactaag agaaagagct tgtctggagc ctccatatag gtggcaattc ctccccaaag
     9541 taagagtaaa acagacgtaa ttcctacaaa caaaaggata ggccaatgat tttcaggaaa
     9601 atgttgtaag agttgactgt actggtaggc tagaaagccc aacaggacaa gcaggaacaa
     9661 gacaaagtgg tcattgagca catagcgcag ataacaaaga cactccttac gaaaggcctg
     9721 ctttctcttt aaaaacaagt ctttcataga tcctcctctt tggtcagagc caagtaaata
     9781 tcattcaaac tagcctcagg catatcaaag gcttcacgta gttgcaggag attgcctttg
     9841 gcacgcacct ctcccttgtg aagaatgaca aaggcatcac acatcttttc cgccgaatcc
     9901 agcacgtggg tactcatgag aatagacttg cccttttgct tctccacttc caaaagctga
     9961 atcaaatcag aaatagccag cggatcaaga ccaaggaaag gctcatccac gatgaaaaga
    10021 cttggatcca ccacaaaagc acagataatc atgaccttct gcttcatccc ttttgaaaaa
    10081 tgaacaggga accagtctaa tttctgttcc aaacggaaca tttttaacaa gggctctact
    10141 cgttcgaaag ccactttttg ctcaataccg taagccatag caaccgtttc gatatgctct
    10201 ctgagggtca attcctcata cagactaggc gtctcaggaa tgtagccaat ctgcttgcgg
    10261 tagctagtcg catctccttg cagagtcagg ccattgatat tgatggagcc actataaggt
    10321 gccaacagac cgataatctc attgatcgtc gttgatttcc cagcaccatt gagaccaatc
    10381 aaaccgacca actgcccact ttcaacagta aaggacacat ctttcaaaac aggaacatga
    10441 acatagccac ctgtcaggtt tttaatttct aacatatttt ctccaaatct ggtataatgt
    10501 agctatatta tatcaaaatt cagtacagta gaggtagatt ttatgtcaga ttgcattttt
    10561 tgtaaaatca tcgcagggga aattcctgct tcaaaagtat atgaagatga gcaggtcctt
    10621 gcctttcttg atatctctca agtaacacta ggacacacct tggtcgtgcc aaaagaacac
    10681 tatcgcaatc ttttggagat gaatgctacg agcgccagcc aactctttgc ccaagtacca
    10741 aaagtagctc aaaaagtcat gaaagtcact aaggctgctg gtatgaatat catttccaac
    10801 tgtgaagaag tcgctggtca aacagttttt catactcacg ttcaccttgt gcctcgctac
    10861 agtgctgacg atgacctcaa gattgatttt atcgcccacg aaccagactt tgacaaactt
    10921 gctcaagtcg ctgaaaccat caaaaacgct taaggagttg ctatgaaatt atccaaccta
    10981 ctgctatttg caggagctgc agccggaagt tatctggtta caaaaaatcg ccaaaccatc
    11041 acagatgaag tcttgaatac cactgaccgc gttcaagcta tcaaagacga tgtggatatt
    11101 atccaaaata gcctgcaaat catcgaccag caaaaagaac ttatcaagga ataccaagaa
    11161 gacttgactt acaagtttaa ggtcttggaa aaggatatcc agactagact agctgtgata
    11221 aaagaaatgc agggaactga agataagtaa aaagagcccc ccggctcttt tttaaaacgt
    11281 aaacaagtta tagtgaattg aatttagaat agcacatcat agtttctaaa gcattgttag
    11341 agattacttt aaaatcctct tatcaatttg ttcatattct atttcaatct actatatata
    11401 tcccatcaac tatgcatcat aatttaggta actcatactc aataaaaatc aaaaagcaaa
    11461 ctagaaagct aggcacagac tgctcaaaac accgttttaa ggttgtggat agaactgacg
    11521 aagtcagctc aaaacactgt tttgaggttg tggatagaac tgacgaagtc agtaaccata
    11581 cccatgacaa gccgacgctg acgtggtttg aagaaatttt tgaagagtat cattcaccat
    11641 ttcacaacta aatcgaagac tttctgccgt aatgaaaaca cctgaaacag cttggtttca
    11701 gctgtccgga aactttaaga cttaggttca aagtttaggt atggaacttc gaaggaggtc
    11761 gctaccgtcc gtcattactt aggaaagtct taaaaaatct ataaagtaaa aagagcccga
    11821 cagctctttt tgtttatact caatgaaaat caaaaagcaa actaggaaac tagccacggg
    11881 ctgctcaaaa cactgttttg aggttgtaga tacgactcac atatatacgg caagccgacg
    11941 ctgacgtggt ttgaagagat tttcgacgct gacgtggttt gaagagattt tcaaagagta
    12001 ttattctcca tcaaaggcat ctttaatatg gtcaaagaag ccttttttct ttggatttac
    12061 tttcaagtca ccagcagccg cgaattcttt caaggctact ttttggcggt cgttcaagcc
    12121 tgtcggtgtt acgacattaa cagtaacgta ttggtcacca actgcaccgc cacgaaggct
    12181 cggtgccccc ttactacgta ggcggaattt cttaccagtc tgagttccct ctggaataac
    12241 caattcaaca tcaccgtgaa cagttggaat atctactgta tcaccaagag ccgcttggac
    12301 aaagttgagg ttgagattgt agaagatagt cgttccttca cgttcaaact tgtcgctagc
    12361 ttctacagaa actactacat acaagtcccc ataaggtcca ccgttaaagc ctgcttcgcc
    12421 ttgaccagcg aggcgaattt gttgacctgt ttccacacca gcagggattt tcacatgtac
    12481 gctatgagct tgtttctcat gacctgttcc atgacaggtt gtacatggat atttgatttc
    12541 ttttcctcga ccgtgacaga catcacaggt tacttggcga cgcatcatac caagaggagt
    12601 ctgcgtatcg acgttaatga caccagcgcc atgacagcgt ccacaagtga ctggacttgt
    12661 ccctggctta gcaccagagc cattacatgt acgacagcca gcttcacgat gatacttaac
    12721 ttccttctca gttccgaaga tagcttcttc aaaggtcaaa ttgacacgat actggagatc
    12781 atctccttgg cgaggagcgt ttggattgcg cgaagaaccg cctccgccga agaaacttga
    12841 aaaaatatcc tcaaaaccac cgaagccacc tgccccattg aaaccaccga aaccaccagc
    12901 tccaccaaaa ccaccattgg cgcctgcagc accatactgg tcataggcag cacgtttttg
    12961 gtcgtcactc aaagtctcat aggcttcttg aacttccttg tacttgtcct cagcaccagg
    13021 ctccttgttg atatctgggt gatatttttt ggaaagctta cgataagcct ttttgatctc
    13081 gtctgccgaa gcgttttttg acacccccag acgatcataa aattcagtat tgttcataca
    13141 agataccaag accgtaaaat tcgactgaaa aataggaaat ctgacgctgg agcgacgctc
    13201 ctagacagat ttctcttttt tccgagaatt taggtcgggt tcaattcctt tcttttatat
    13261 tgatgagata atactccagc cactcggccc tatccctttt taccgaaaaa cagaggctga
    13321 gttgcaacct ctgtggttag attattcatt tgaaataaaa atggttgtat tatctctagt
    13381 agtaatcttc aaagaccttt tagctaaatc aaactcaaat ttattatagt gtgggtcttg
    13441 tgttttatat aggtgtaact cctgacatat atgatccgaa aagtaaatca taacatcttt
    13501 aaacacagaa gtgtggtcat atttactctt accaacagct acttctgtaa attctttata
    13561 aatgacattt ccatttcttt ccacagtcac cagcatttct gttggattat aatccaaatt
    13621 aaataattct tcaaaaaact ttatcttttc atgataatct gcaatgtcag aaagattatt
    13681 tttattaaca ctcataacac tagcccctta tttttcagta aactctccgt ctacgacgtc
    13741 atcgcctgcg tttcctgttg cttgtgcgcc ttctgctcct tcttgagctt gttgcgctgc
    13801 tgcagcttgt tcgtagagtt taacagcaag tccttgagct ttttcgttca atgcttcaag
    13861 ttttgctttc atgtcgtcca agttgttgtc ttcttgagct ttcttaaggt catcaagggc
    13921 agcttgggca gcgtcacgtt ctgcgtcgaa gcctttacct tcagtttcct tgattgtctt
    13981 ttcagtcgca aagattgctt ggtctacttc attacgaagg tctacttctt ctttacgttt
    14041 cttatcggct tcagcgtttg cttctgcatc tttcatcatg cggtcgattt cttcgtcagt
    14101 caaacctgag ttcgattgga tgacaatagt ttgttctttt tgagttccaa ggtctttggc
    14161 cttaacagac acgataccgt tcttgtcgat gtcaaatgtt acttcgattt gaggaattcc
    14221 acgaggtgca gctgggatat cagtcaattg gaagcgtcca agagtcttgt tatctgctgc
    14281 cattgggcgt tcaccttgaa gaacgtggat atcaacggct ggttggttgt ctgctgctgt
    14341 tgagaagact tgtgatttag atgttgggat tgtagtgttg cgatcgataa gttttgtaaa
    14401 tactccaccc attgtttcga taccaagtga caatggcgtt acatcaagaa ggacaacgtc
    14461 cttgacatca ccagtaatca caccaccttg gatagccgca cccatagcaa ctacttcatc
    14521 agggtttact gatttgtttg gttctttacc agtttcagct ttaacagctt caacaacggc
    14581 agggatacga gttgaaccac caacaaggat aacttcgtcg atttctgaca agctcaaacc
    14641 tgcatctgaa agggcttgac gaactggaac ttttgtacgt tcaacaaggt cacgagtcaa
    14701 atcgtcaaat ttcgcacgag tcaaagtcat ttccaagtga agaggtccag cctcacctgc
    14761 agtgataaat ggcaagctga tttgtgttga agttacacca gaaaggtctt tcttcgcttt
    14821 ttcagccgca tctttcaaac gttgcattgc catcttgtca gtagacaagt cgataccgtt
    14881 ttctttcttg aattctgcta ccaagtggtc aatgattttt tggtcaaagt cgtcaccacc
    14941 aagtttgttg tcccctgcag ttgacaatac gtcgaagaca ccgtcaccca attcaaggat
    15001 agagacgtcg aatgtaccac caccaaggtc aaataccaag attttttctt ctttgtcagt
    15061 cttgtccaaa ccataagcaa gagctgctgc agttggttcg ttaacaatac gttctacttc
    15121 aagaccagca attttaccag cgtcttttgt tgcttgacgt tgagcgtcgt tgaagtaagc
    15181 cggaactgtg ataacagctt tggttacttt ctcaccaagg tagtcttcag cgtagccttt
    15241 caagtattga aggatcatag ctgagatttc ttgtggagtg tattcttttc catttgcaga
    15301 aactttttca gaagttccca tcttagattt gatagagata actgtatctg ggtttgtaac
    15361 tgcttgacgt tttgcagcat caccaacgat gatttctccg tttttgaatg agactacaga
    15421 tggagttgtg cggtttcctt ctgggtttgc gatgattttg ctttcagttc cttcaagaac
    15481 tgcaactgct gagtttgttg tacctaagtc aataccgata attttagaca tgtgtttttc
    15541 tccttgttag ttaattttct atttttcttt ttgatactct tcttaagtgg cgacgccgtc
    15601 agagcttgac ttcgtcaatc tctttgacta aactttgagc ctaaggtctc aaaatttgcg
    15661 caaatagcac cacggcgaag agtatcgtct ttggttcgct tcgctcacta ttacaaagcc
    15721 aaacatattt tatctttctt catagtttat tgtcgtttcg gacaagtttt ctattatgta
    15781 aattgcgaca cgaggagtcg aaatcgattt tatttcgacg acgagttagt aaggaagcta
    15841 ggcaaacgtc atagcgattg ccgttttctg acgagttgct ttagctaccg tcagaattgc
    15901 cgaatcgaac acgccctaag ctctgagtaa aaaagataga ttttcttgtg ttcatcgaac
    15961 acttcgtcaa tctcctattt ttactgcgag ctttttacga gctttgtatc ttagttatac
    16021 accactacca ttgctgggcg taggatgcgg tcatggagtt tgtagccttt ttgaaagact
    16081 tgggcgatgg tatctactgg gtgttcatcg tctgctggga gagtttggat ggccatatgg
    16141 tagttatggt caaattcgcc atctgctgcg atttcttcaa ttccttcttc tttcaaagcg
    16201 tgaatcaagc tttcttgcac catccccaag cccttcttca catcatctgt caaaccttca
    16261 actgcaagtg cacgctcaag gttgtcaaga gatggtaaga ttgcttttgc caagtcctgg
    16321 ctacgataac gttgcaagtt ttgacgttct tcattggcac ggcgttggat attttgcatt
    16381 tctgcatgag cgcgaagata tttgttttcg aactcatctg cacgttcatt tgccaagtcc
    16441 aactcagact tttcaggagt tgtttcttca gctgtttcca caacttcctc ttcttgaact
    16501 tcttctactt cttcattttt tatatcttgg gccatgttcg cctcctttaa tgatttcaat
    16561 cttaatgtac ttcgtaatga ttactgctga ggtagcggta aaaatctgtc aacttcatgg
    16621 tcaaaacacg gttgaccaca ttgacttgat tgattagctg ttggtaatcc agattaactg
    16681 gaccgataat ggctagaatt ccaactcccc gataaggaat gaggaactta ctactaatca
    16741 ccgctaggtc agctaaacag gactcttgac cgtctgcaac acgaacattt tgcatctgat
    16801 cctcacgcaa cccctcacga atctccaagg ccaccttttg cggttggtca aagaactgat
    16861 aggcttctag attggcaaaa ttcaagagat tgaccttgcc cgccatcaca atgttttcgt
    16921 tgaacatttc cttaaagatg tgttcaaaga gatcgatgac attatccgtt gttgtaaagt
    16981 aacgctggat aatctgcgga atctccgtcc gaatcttgta gtgaatatct aaaacggtgt
    17041 gaccgaggaa acgttcctga atgatgctct tcagtttcag caaatcctcc tgcaagaagt
    17101 tccttggaat cagaaactga ctagtaaccg ttcgcgactc gtctagggta aataccgcca
    17161 aggctgtatg ttgccccaaa acaacgatat caaaggctgt caaacgttgc ctgctcggct
    17221 caacatccag tgccactacc gtacagccac tcaggcctgt tagcaagtta gcagcctctt
    17281 gcagaatatc ctccaatttg aagaattcct gatcaaaggc tttgacaatc tcatatacct
    17341 cattttcagc cagccggtga aaatccagtg agtgtttcac atagtactga aaaccagcaa
    17401 cacttggcat ccgaccgctt gaagtatgag ccttctcaag caacccttgt ttttctagtt
    17461 ccgccatgtc attacgaatg gttgcactgc tagagttaat agactcttgc aaggcttttg
    17521 atccgacagg ttcgtgcgtt ttggtaaaga tgtcaataat cagatttaaa atatcctgct
    17581 gacgctctgt aaccatctca tcactcctct ctgtctgatc aattagcact caatgcatcc
    17641 aagtgctaac ttatgattct attatacacc cttaaaagag aatgtcaaga caaaaactca
    17701 aaaaattagc actcttttat caagagtgct aaaaatcaat ctgaagacct agaaccttgc
    17761 tattcatcta ctcggtattt cctttttagt ctgaaataac catgaattag ataagaaatc
    17821 agaaaagcat ataaaacaaa aataagaaag aaagacatag aaagatcctc tctaaacaaa
    17881 ctcgtacaaa caacaagacc acctaagaaa gtagttgtac aggaacgaag tctagatcgc
    17941 ataacttccc atttgagccc cttactcata tagacttgat cctctggaag taaatcagaa
    18001 gacgatttac gaagaatcga acaagaacct gctcctatca attcccaacc tctatctcta
    18061 aaatcttgca gttcatgctt atatttttta agaaatctag aatcatagat acggtagatg
    18121 acatcgtctg gttgacattg gtcaaaatag aacaaaccaa aacgactcgt tctatacctc
    18181 caacctttca aatgcatctc atgtaaatat tcttcttcct tgtccaaatc aacaatggtg
    18241 aaaatccgaa attctactct gctattcatt gtcttacccc aaaattagaa aacatgcctg
    18301 gcgttattta ttagataatt ctttccactt ttgactcaat ctccaaaaaa tataagaaat
    18361 ctgaatcgca aaaactatca ataaaaccca atctattatg aaaatcaaaa acactttcca
    18421 actgaaagaa ctacctccag tgacaaactt tgagcaaaac ggtagtagag ctaaaaagag
    18481 aagtaaaata ggaagcatcc gcattgttaa aatccgtttg gcataaaaaa atctttattt
    18541 aaactaaaat attatagcaa aatttacgcc agtttttgaa cggctgatgt agatatttta
    18601 tactttcaaa atgtttaaat gtgattattt atttttgaaa aatagctcac cagcccgact
    18661 gaaagtgctt atagaatgat aataagtcgc ctgccgaaaa cagcggaaaa tagcggtgtt
    18721 atgcggagat aatctgacgc gatgcgaaag tatattgcat acttattttc aacaatttag
    18781 cagagtattt ttataagtgt gatataatag aagtataatt tgttctgata gtttatttta
    18841 tggagaagta gatttttaga atgcggaggg ttcaatatgg ttgagtttat aaagtctaag
    18901 aaagaaatga gtgaggagga tattaaagca aatttcatca ctcctgctat tgtatccaaa
    18961 ggatggaaaa atggtgagca tatcgcttac gaagaatact tcactgatgg tcgaattgag
    19021 gttagaggag ataaggctcg tcgtaaagaa ggaaaaaaat cagactattc actgtattac
    19081 caatttggaa ctcgaattgc aattgttgag gcaaaggata ataaacacag cgttcgagca
    19141 ggattacaac aagctattga atatggagag attttagatg ttccatttgt ttattcttcg
    19201 aatggtgatg gctttattga acacgaccgt atcacgagag aagaacgtga gctggagtta
    19261 gacgaattcc ctactcgtga agaattattt tctcgtatga cgaaggaaaa aggattgacg
    19321 tacgaaatta cagaagctat ctcaactcca tactatacag acgccttctc aatgaaaacg
    19381 ccacgctatt atcagcaaat agctatcaac cgtactattg aaacagttgc cagaggacaa
    19441 aaacgagtaa tgtttgtgat ggcaacagga acagggaaaa cgttcatggc ttttcaaatt
    19501 attcatcgcc ttcgaaaagc tggtttggct aaacgagttt tattcttagc agatagaaac
    19561 atcttagtag accaaacgat ggctgaagac tttaagccat tcgaaaaggt aatgacgaaa
    19621 attacaccaa aacttttgac tgctcctgaa aaattaaatt ctttcgaaat ttatctaggg
    19681 ctttatcagc aactaactgg tgaagatgga actgaaacac attatcaaaa atttgacaaa
    19741 gacttctttg atttaatcgt aattgatgaa gcgcaccgtg gttcagctaa ggaaaacagt
    19801 aactggcgta aggtaattga ttatttcagt tctgcgacac agattgggat gaccgctact
    19861 cctaaagaaa ccaagaatgc ttccaatacg gaatactttg gtaagccaat ctatacttat
    19921 agtttaaaac agggaatcga ggatggtttt ttggctccat atcgtgttat gagggttaat
    19981 ttagatgtgg atgtggatgg ttatcgtcca gaaactggaa aagttgatgc taacggacaa
    20041 ttaatagaag ataggtacta cggcaggaaa gattttgata aaaccattgt cattgatgat
    20101 agaacgcaaa gagttgccaa gtttgtttct gattatatga agcaaaacaa tgcacgattt
    20161 gataaaacaa ttgttttttg tgttgatatt gaccatgccg agcgaatgcg tgctgcactt
    20221 gtaaaagaga atctagactt agtccaagaa gactatcgtt atgtcatgca agtaactggt
    20281 gacaacgctg aaggaaaagc tcaactggat aactttatgg atgtcaattc taattttccc
    20341 gctattgtaa caacgtctaa attattaacg acaggagtta atgctaaaac atgtcgtttg
    20401 attgttttag actctaatat ccaatccatg actgaattta aacaaattat tggtcgtggc
    20461 acacgtcttt atcctcaaaa ggggaaagaa ttttttacga ttattgattt tcgaaatgtt
    20521 accaatttgt ttgctgaccc tgattttgat ggtgagccag tgaaggtgct ggaaacaggt
    20581 gcgaaaacag tcagtggttc tacgcctggt ttcgtaggtg aggaaggtga cccagtagaa
    20641 aaatatatcg ttacagacaa gcaggttacc attcttaatt ctactgttca agtattggat
    20701 gaaaacggga aactgattac cgaaagcctg accgactaca ctcgaaagaa tatcttaggt
    20761 agctacgcca ctttgaacga ttttatcaca gtttggcata cggcagataa gaaacattat
    20821 gggaagtttg ctgatggaag cactcaagaa attgatgttc cttatgatat tcctgatact
    20881 tgggagtggg tgaggttttc tacattggtt gaaattgtca gaggtggctc tccacgacca
    20941 atcaaagatt atcttacttc tgaagtagat ggaataaatt ggataaaaat aggtgatact
    21001 gaaaagggtg aaaagtatat aaataatgtt aaagaaaaaa tcaaaaaatc agggcttaac
    21061 aaaactagat ttgtaaaaaa aggtacattt ttgttaacta attctatgag ttttggtaga
    21121 ccttatattt tgaatgttga tggtgcaata cacgatggat ggttggctat ttcgaactat
    21181 gaaaactcat taaataaaga ttacctattc tatattcttt catcaaatgt agtttattct
    21241 caatttctat ctctaattag tggagctgtt gtgaaaaact tgaatagtga taaagttgct
    21301 tctattctta tc
//
LOCUS       DAVBDR010000035        21272 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.035, whole genome shotgun sequence.
ACCESSION   DAVBDR010000035 DAVBDR010000000
VERSION     DAVBDR010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21272)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21272)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21272
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.035"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            complement(<1..787)
                     /locus_tag="VQ540_001328"
     CDS             complement(<1..787)
                     /locus_tag="VQ540_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019770457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2545127.1"
                     /translation="MLYVGIDIAKNKHDVTALNVPGKTVLKPLTFSNNKAGFELLDLS
                     LRQLNQDCLIALENTGHYAFNLLNFLHEQGYKVYTYTPLLIKEFAKSLSLRKTKTNKK
                     DAHGIALKLLSDPNREQFQHDNRQVELKILARHIHRLKKKQSDWKVQYTRCLDIIFPE
                     LDKIVEKHSEYTYQLLTCYPNPQKRLEAGFDKLIEIKRLTASKIQDILSVAPRSIGTT
                     SPAREFEIIKHYKRLIDKAETCVNDLMAEFNSVITTVTGIGNRL"
     gene            1042..1887
                     /locus_tag="VQ540_001329"
     CDS             1042..1887
                     /locus_tag="VQ540_001329"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HET2545128.1"
                     /translation="MYLIEILKSIFFGIVEGITEWLPISSTGHLILAEEFIQYQNQNE
                     AFMSMFNVVIQLGAILAVMVIYFNKLNPFKPTKDKQEVRKTWRLWLKVLIATLPLLGV
                     FKFDDWFDTHFHNMVSVALMLIIYGVAFIYLEKRNKARAIEPSVTELDKLPYTTAFYI
                     GLFQVLALLPGTSRSGATIVGGLLNGTSRSVVTEFTFYLGIPVMFGASALKIFKFVKA
                     GELLSFGQLFLLLVAMGVAFAVSMVAIRFLTSYVKKHDFTLFGKYRIVLGSVLLLYSF
                     VRLFV"
     gene            complement(2034..3095)
                     /gene="dinB"
                     /locus_tag="VQ540_001330"
     CDS             complement(2034..3095)
                     /gene="dinB"
                     /locus_tag="VQ540_001330"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HET2545129.1"
                     /translation="MLIFPLLNDLSRKIIHIDMDAFFAAVEIRDNPKLRGKPVIIGSD
                     PRQTGGRGVVSTCSYEARAFGVHSAMSSKEAYERCPQAVFISGNYEKYKSVGLQIRAI
                     FKRYTDLIEPMSIDEAYLDVTENKLGIKSAVKIARLIQKDIWQELHLTASAGVSYNKF
                     LAKMASDYQKPHGLTVILPEQAEDFLKQMDISKFHGVGKKTVERLHQMGVFTGADLLE
                     VPEVTLIDRFGRLGYDLYRKARGIHNSPVKSNRIRKSIGKEKTYGKILLAEEDIKKEL
                     TLLSEKVALNLHQQEKAGKIVILKIRYEDFSTLTKRKSLAQKTQDASQISQIALQLYE
                     ELSKKERGVRLLGITMTGF"
     gene            3443..5767
                     /gene="pflB"
                     /locus_tag="VQ540_001331"
     CDS             3443..5767
                     /gene="pflB"
                     /locus_tag="VQ540_001331"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HET2545130.1"
                     /translation="MVVKTVVEAQDIFDKAWEGFKGVDWKEKASVSRFVQANYTPYDG
                     DESFLAGPTERSLHIKKIVEETKAHYEETRFPMDTRPTSIADIPAGFIDKENEVIFGI
                     QNDELFKLNFMPKGGIRMAETTLKENGYEPDPAVHEIFTKYVTTVNDGIFRAYTSNIR
                     RARHAHTVTGLPDAYSRGRIIGVYARLALYGADYLMQEKVNDWNAIKEIDEETIRLRE
                     EVNLQYQALQQVVRLGDLYGVDVRKPAMNVKEAIQWVNIAFMAVCRVINGAATSLGRV
                     PIVLDIFAERDLARGTFTESEIQEFVDDFVMKLRTVKFARTKAYDQLYSGDPTFITTS
                     MAGMGNDGRHRVTKMDYRFLNTLDNIGNSPEPNLTVLWTDKLPYNFRRYCMHMSHKHS
                     SIQYEGVTTMAKDGYGEMSCISCCVSPLDPENEEQRHNIQYFGARVNVLKALLTGLNG
                     GYDDVHKDYKVFDIEPIRDEVLEFESVKANFEKSLDWLTDTYVDALNIIHYMTDRYNY
                     EAVQMAFLPTKQRANMGFGICGFANTVDTLSAIKYATVKPIRDEDGYIYDYETIGDYP
                     RWGEDDPRSNELAEWLIEAYTTRLRSHKLYKDAEATVSLLTITSNVAYSKQTGNSPVH
                     KGVYLNEDGSVNLSKLEFFSPGANPSNKAKGGWLQNLNSLSSLDFSYAADGISLTTQV
                     SPRALGKTRDEQVDNLVTILDGYFENGGQHVNLNVMDLNDVYEKIMSGEDVIVRISGY
                     CVNTKYLTPEQKTELTQRVFHEVLSMDDALDALS"
     gene            complement(6134..6352)
                     /locus_tag="VQ540_001332"
     CDS             complement(6134..6352)
                     /locus_tag="VQ540_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2545131.1"
                     /translation="MMSIREQDLQDIGAIIKYKNFHSPFDTFKYLKDMGFDTIDLSVL
                     LEGFSYAYGMDWLEKFFKENQDKLREFY"
     gene            complement(6448..6686)
                     /locus_tag="VQ540_001333"
                     /pseudo
     CDS             complement(6448..6686)
                     /locus_tag="VQ540_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397100.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(6679..6963)
                     /locus_tag="VQ540_001334"
     CDS             complement(6679..6963)
                     /locus_tag="VQ540_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002923859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2545132.1"
                     /translation="MDWYDYMIQASKQSQFNASHWFRYLRKVIFEDYSYLTNQDVEKL
                     LDSKELTRFQKISLKYAFQEHTPTHKYVISLNKPAKLTNVQKLMEKYKHG"
     gene            complement(7575..7745)
                     /locus_tag="VQ540_001335"
     CDS             complement(7575..7745)
                     /locus_tag="VQ540_001335"
                     /inference="COORDINATES: protein motif:HMM:NF024172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2545133.1"
                     /translation="MTKQVPKFTKDTAQLYTCKWLLYNKVTKMYDHTVVNHSVREYIT
                     DSISTNTIEETG"
     gene            complement(8395..9618)
                     /locus_tag="VQ540_001336"
     CDS             complement(8395..9618)
                     /locus_tag="VQ540_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HET2545134.1"
                     /translation="MITKQSAFLQNRATILEFLYRNPATSRTDIVNETGLTPATTTNI
                     IKELSEQSLIYETGDEFSEFSGSGRRRKTISITDNIPYVVGGIEINVLGIFLSLCDLQ
                     GKTLFETEILNEDYPISEINSTITNMIKTAIEYVPLETKLLGFGLSIPGHYNKDSGSI
                     ITNNPIWESFNLLNVIKRFNFPFIVKNNIDCMAIGQYLFNPHNTPDNFIFLHAGLGIY
                     TSFFTKEKIGASKNPYIGEIGHTIVELNGQYCECGKKGCLQTYISDAWLIKHAQLLFK
                     NSQLTVLKSLVKTEKDIHLDTLLTAYNLGDSALRQQIDKGVNLLATSIANLLLINPAD
                     KIYINSQLLNYQPFTHEVRDKIQDQLHFVPFTRNIEIEILPYNKHRGSIGACALAIVA
                     FFIEHSNVLQDIISP"
     gene            9786..11108
                     /locus_tag="VQ540_001337"
     CDS             9786..11108
                     /locus_tag="VQ540_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HET2545135.1"
                     /translation="MNNILAFLETKVAPFGEKVGNQRHLKAIREGFMMAMPLILVGSL
                     FLILISWPQEDFTNWLNSVGLLSILTTMNQSTVAIISLVACFGIAYRLSEGYGTDGPS
                     AGIIALSSFVLMAPRFSSMVYDKNGEQVKQLFGGAIPFSSLNASSLFMAITIGLVTAE
                     IYRMFIQRGITIKMPSGVPDVVSKSFSALLPGFTTFVLWALVLKGLEAAGVAGGLNGL
                     LGAIVGTPLKLIAGTLPGMILCVIVNSFFWFCGVNGGQVLNAFVDPVWLQFTTENQEA
                     VAAGQTLQHIITLPFKDLFVFIGGGGATIGLAICLFLFSKSRANKTLGKLAIIPSIFN
                     INTAILFTFPTVLNPIMLIPFIATPTINALITYVSMAVGLVPYTTGVILPWTMPPIIG
                     GFLATGASWRGALLQVVLILVSVAIYYPFFKIADKRNLEKEKATVGGK"
     gene            11110..12996
                     /locus_tag="VQ540_001338"
     CDS             11110..12996
                     /locus_tag="VQ540_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000236922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4838 domain-containing protein"
                     /protein_id="HET2545136.1"
                     /translation="MVIRVFDQQKNTYSSFALEELSYYINRVFKTDIELVEEKEADIF
                     VGLVNKEDRKDHVLISLDKGKGRIESNTIVGLLIGIYRMFHEFGVVYTRPGRGHDFVP
                     ELRFEDFLDKELSIDETASYYHRGVCIEGADSFENILDFIDWLPKIGMNSFFIQFENP
                     YSFLKRWYEHEFNPYLNKEKFSNELVQELSDRLDKELQKRGLIHHRVGHGWTGEVLGY
                     SSKFGWESGLSISEEKKPYVAEINGKRELFNTAPILTSLDFSNPDVADKMVEIIKDYA
                     KKRPDVNYLHVWLSDARNNICECENCRQELVSDQYIRILNQLDRALTSEGLDTKICFL
                     LYHELLWAPQKEKLDNPERFTMMFAPITRTFEMSYADVDFDNSIPTPKPYLRNKIILP
                     NSLEENLSYLFEWQKTFKGDSFVYDYPLGRAHYGDLGYMKISQTIYRDVSYLSNLHLN
                     GYISCQELRAGFPHNFPNYVMGEMLWKKTRSYEELIEEYFSALYGSNWQSVVEYLEKL
                     SSYSSCDYFNAIGSRQNDVLANHYYIAYNLADNFLPIIEENISKLLNSQKDEWKQLSY
                     HREYVVKMAKALYLQATGKTRQAQDEWRNVLNYIRGHELLFQSNLDVYRVIEVAKNYA
                     GFHL"
     gene            13164..13508
                     /locus_tag="VQ540_001339"
     CDS             13164..13508
                     /locus_tag="VQ540_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000836781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HET2545137.1"
                     /translation="MKSKEEINMLGFTIVAYAGDARSDLMDALAFARDGYFEQARELV
                     ESANDSIVSAHREQTNLLAEEASGDNFEVSFIMIHGQDTLMTTMLLYDQVKFFIDEYE
                     RIRKIEEHIGLQ"
     gene            13518..14930
                     /gene="lacG"
                     /locus_tag="VQ540_001340"
     CDS             13518..14930
                     /gene="lacG"
                     /locus_tag="VQ540_001340"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HET2545138.1"
                     /translation="MENLQVKALPKEFLLGAATAAYQVEGATRVDGKGTNMWDVYLQE
                     NSPFLPDPASDFYYRYEEDITLAAEHGLQALRLSISWVRIFPDIDGEPNILAVRYYHR
                     VFQSCLKHNVIPFVSLHHFDSPQKMLETGDWLNRENIDRFIRYARFCFQEFTEVKHWF
                     TINELMSLAAGQYIGGQFPPNHHFQLSEAIQANHNMLLAHALAVLEFHQLGIEGEIGC
                     IHALKPGYPIDGQKENILAAKRYDVYNNKFLLDGTFLGYYSEDTLFHLNQILEANNSS
                     FIIEDGDLEIMKRAAALNTMFGMNYYRSEFIREYKGENRQEFNSTGIKGQSSFKLNAL
                     GEFVKKPGIPTTDWDWNIYPQGLFDMLLRIKEEYPQHPVIYLTENGTALKEVKPEGEN
                     DIIDDSKRIRYIEQHLHKVLEARDRGVNIQGYFIWSLQDQFSWANGYNKRYGLFFVDY
                     ETQKRYIKKSALWVKGLKRN"
     gene            15000..16679
                     /locus_tag="VQ540_001341"
     CDS             15000..16679
                     /locus_tag="VQ540_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HET2545139.1"
                     /translation="MDKLVAAIEKQQGKFEKISTNNYMIAIKDGFIATMPLIMFSSFL
                     MIIIMIPKNFGVELPSPAIAWMRKVYMLTMGVLGIIVSGTVAKSLAGNVNRKMPPGKV
                     INDTSAMLAAICGYLVLTVTLVVDEKTGSTSLSTNYLGSQGLITSFVSAFITVNVYRF
                     CIKRDITIHLPKEVPGAISQAFRDIFPFSFVLLISGLLDIVSRFSLDVPFAQVFQQLL
                     TPIFKGAESYPAMMLIWFMCALLWFVGIHGPSIVLPAVTALQLSNMEENAQLLANGQF
                     PYHSLTPNFGNYIAAIGGTGATFVVPFILIFFMRSKQLKSVGKATITPVLFAVNEPLL
                     FGMPVILNPYLFVPFLMTPPVNVFLGKVFIDFFGMNGFYIQLPWAFPGPLGLLIGTNF
                     QLISFVFLSLMLVVDILIYLPFCRAYDRQLLVKEDIASSNDIILEEDTSEIMPGEIDV
                     IKSKELKVLVLCAGSGTSAQLANAINEGAQLAEVRVIANSGAYGAHYDIMGVYDLIIL
                     APQVRSYYREMKVDAERLDIQIVATRGMEYIHLTKSPSKALQFVLEHYQAV"
     gene            complement(16805..18244)
                     /locus_tag="VQ540_001342"
     CDS             complement(16805..18244)
                     /locus_tag="VQ540_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HET2545140.1"
                     /translation="MNKSMIRYLLSKLLLIEAVLLLVPVAIAVYYRESSQVFTALFST
                     IGILVLLGGSGSLQKPKNQRIYAKEGVLIVALCWILWSFFGGLPFVFSGQIPSLIDAF
                     FEISSGFTTTGASILNDVSVLSRSLLFWRSFTHLIGGMGVLVFALAIMDNAKNSHLEV
                     MKAEVPGPVFGKVVSKLKNTAQILYLLYLALFSLFVIIYYLAGMPLYDSFVIAMGTAG
                     TGGFTVYNDGIAHYGSSLITYLVSIGVLVFGVNFNLYYYLMLRRIKAFFGDEELRAYL
                     VIVLVSTGLISLNTLYLYPGFSKSFEMTFFQVSNIITTTGFGYGDITNWPLFSQFILL
                     FLMAIGGSAGSTAGGLKIIRGLILSKIAKNQILSILSPHRVLTLHVNKTVIDKDTQHK
                     ILKYFVIYAMILLALIFIVSLDSNDFLVVTSAVFSCFNNIGPILGTTSSFSIFSPISK
                     ILLSFAMIAGRLEIYPILLLFMKRTWSKR"
     gene            complement(18248..19597)
                     /gene="trkA"
                     /locus_tag="VQ540_001343"
     CDS             complement(18248..19597)
                     /gene="trkA"
                     /locus_tag="VQ540_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk system potassium transporter TrkA"
                     /protein_id="HET2545141.1"
                     /translation="MKIILVGGGKVGFALCRSLVAEKHDVLLIEQDEAVLNHIVSRFD
                     IIGILGNGADFAILEQASVQDCDIFIALTEHDEVNMIAAVLAKKMGAKETIVRVRNPE
                     YSNSYFKEKNILGFSLIVNPELLAARAIANIIDFPNALSVERFAGGRVSLMEFVVKST
                     SGLCQMPISDFRKKFGNVIVCAIERDHQIIIPSGDMTVQDKDRIFVTGNRVDMILFHN
                     YFKSRAVKSLLIVGAGRIAYYLLGILKDSRIDTKVIEINPEIASFFSEKFPNLYIVQG
                     DGTAKDILLEESAQHYDAVATLTGVDEENLITSMFLDRVGVQKNITKVNRTSLLEIIN
                     APDFSSIITPKSIAVDTIMHFIRGRVNAQYSDLQAMHHLANGQIETLQFHIKEANKMT
                     AKPLSQLKLKKGVLIAAIIRKGKTIFPTGEDMLEVGDKLLVTTLLPNITKIYDLIAR"
     gene            19785..20633
                     /locus_tag="VQ540_001344"
     CDS             19785..20633
                     /locus_tag="VQ540_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-adenosyl-l-methionine hydroxide
                     adenosyltransferase family protein"
                     /protein_id="HET2545142.1"
                     /translation="MNNNLLVLQSDFGLVDGAVSAMIGVALEESPTLKIHHLTHDITP
                     YNIFEGSYRLFQTVDYWPEGTTFVSVVDPGVGSKRKSVVAKTAKNQYIVTPDNGTLSF
                     IKKHVGIVAIREISEVANRRQNTEHSYTFHGRDVYAYTGAKLASGHITFEEVGPELSV
                     EQIVELPVVATIIEDHLVKGAIDILDVRFGSLWTSITREEFYKLEPEFGDRFEVTIYH
                     ADMLVYQNQVVYGKSFADVRIGQPILYINSLYRLGLAINQGSFAKAYNVGVGSSWTIE
                     IKKIEG"
     gene            20648..21196
                     /locus_tag="VQ540_001345"
     CDS             20648..21196
                     /locus_tag="VQ540_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF-type riboflavin transporter
                     substrate-binding protein"
                     /protein_id="HET2545143.1"
                     /translation="MEIKFTIKQVVAVGIGAALFVVIGMINIPTPVPNTSIQLQYAVQ
                     ALLSIIFGPIIGLLVGLIGHAIKDSLVGYGLWWTWIIASGLFGLVVGLFRKYVRVING
                     VFDWKDILIFNLIQLLANALVWGVLAPLGDVVIYQEAAEKVFAQGIVAGIANGVSVAI
                     AGTLLLLAYAGTQTRAGSLKKD"
BASE COUNT         6427 a         3619 c         4366 g         6860 t
ORIGIN      
        1 ctaaacgatt cccaatccca gtgaccgtcg tgatgaccga gttgaactca gccatcaagt
       61 cattgacaca tgtttccgcc ttgtcaatga gcctcttgta atgtttgatg atttcgaatt
      121 cacgagcagg agatgttgtt ccgatagaac gaggtgcaac tgagaggata tcctgaattt
      181 tagaagcggt caatcgctta atttctatca gcttatcaaa tcctgcctca agccttttct
      241 gaggattagg gtagcatgtc aagagttggt aggtatattc tgaatgcttt tcaacgattt
      301 tatccaactc aggaaagatg atatcaagac aacgagtgta ttgtactttc caatcagact
      361 gttttttctt gagacgatga atatgtctag ccagtatttt tagttctact tgccgattat
      421 cgtgttgaaa ttgttcacga ttggggtcag aaagaagttt aagagcgatg ccatgagcgt
      481 ctttcttatt cgttttagtc ttgcgaagtg ataatgattt ggcaaattcc ttgatgagca
      541 aaggagtgta ggtgtaaact ttatatcctt gttcatgcag gaagttcagt agattaaagg
      601 cataatgtcc ggtattttca agagcgatga gacagtcttg gttgagctgt cgaagagaca
      661 gatctaagag ttcaaaacca gctttattat ttgaaaaagt gagtggttta agaacagttt
      721 ttcctggaac attcaaggct gtaacatcgt gtttattttt agcgatatca atgcccacat
      781 aaagcatggg agtacctcca gatatagtat ttcaagtcta cttggttatc cacgaatttt
      841 ttgccttgtt accttagacg agatcaaacg tctatgcgtt atcaaactca ttaccaattg
      901 aaacaaaagc tgtggttaga gcctttcgga aatcgtcaag cgattggagg aaatgaacta
      961 atccacagtg gcttattcca agtataccac ttgggctttg gcagtagcta actgcgctaa
     1021 ttataatata gggagtaatc tatgtatctt attgaaattt taaaatctat cttcttcggg
     1081 attgttgaag gaattacgga atggttgccg atttccagta caggtcactt gattttagca
     1141 gaggaattca tccaatacca aaatcaaaat gaagccttta tgtccatgtt taatgtcgtg
     1201 attcagcttg gtgctatttt agcagttatg gtgatttatt ttaacaagct caatcctttt
     1261 aaaccgacta aggacaaaca ggaagttcgt aagacttgga gactatggtt gaaggtcttg
     1321 attgctactt tacctttact tggtgtcttt aaatttgatg attggtttga tacccacttc
     1381 cataacatgg tttcagttgc tctcatgttg attatctacg gggttgcctt catctatttg
     1441 gaaaagcgca ataaagcgcg tgctatcgag ccaagtgtaa cagagttgga caagcttcct
     1501 tatacgaccg ctttctatat cggactcttc caagttcttg ctcttttacc agggactagc
     1561 cgttcaggtg caacgattgt cggtggtttg ttaaatggaa ccagtcgttc agttgtgaca
     1621 gaatttacct tctatcttgg gattcctgtt atgtttggag ctagtgcctt aaagattttc
     1681 aaatttgtga aagccggaga actcttgagc tttgggcaat tgtttttgct cttggtcgcg
     1741 atgggagtag cttttgcggt cagcatggtg gctattcgct tcttgaccag ctatgtgaaa
     1801 aaacacgact tcaccctttt tggtaaatac cgtatcgtgc ttggtagtgt tttgctactt
     1861 tacagttttg tccgtttatt tgtataagaa aaaccttgaa ggggcaactc ttcaaggttt
     1921 tatactcttc gaaaatctct tcaaaccgcg tcagctttat ctgcaacctc aaaacagtgt
     1981 tttgagcagc ctgcggctag cctcctagtt tgctctttga ttttcattga gctttaaaat
     2041 ccagtcatgg taatccccaa taggcggaca cctctttctt tcttgcttaa ttcttcatag
     2101 agttgcaggg ctatttggct tatctgacta gcatcttgtg ttttttgagc aagacttttt
     2161 cgtttggtaa gagttgaaaa gtcctcgtag cggattttca aaatgacaat ttttccagct
     2221 ttttcttgtt gatgtagatt gagagcgact ttttctgata gaagagtcag ctcttttttg
     2281 atatcttcct cagcaaggag aatcttcccg taggttttct ccttgccgat tgatttacgg
     2341 atgcgattgg atttgactgg agagttgtga atgccacgag cctttcgata cagatcatag
     2401 cctagtctac caaaacggtc tattagggtt acctcaggaa cttcaagtaa atcagcacca
     2461 gtaaaaacgc ccatttgatg aagacgttct actgtctttt ttcctactcc atgaaatttg
     2521 gaaatatcca tttgtttgag aaaatcctca gcctgttcag gtagaatcac tgtcaaacca
     2581 tgtggttttt gataatcact cgccatttta gctaagaatt tgttgtaaga aacgcctgcg
     2641 gaagcagtta gatggagttc ttgccagata tctttttgaa tgaggcgagc aattttgacc
     2701 gctgacttga taccgagttt attttctgtc acatccaaat aggcttcgtc aatgctcatg
     2761 ggttcaatca aatctgtata gcgcttaaaa atagctcgaa tctggagtcc cacagacttg
     2821 tatttctcat aattccctga gataaagaca gcctggggac aacgttcata agcttccttg
     2881 gaactcatgg cagaatggac accaaaagct cttgcctcat aactacaggt agaaacgact
     2941 ccccgtccac ctgtttgccg agggtcgctt ccaataatga caggttttcc tctgagttta
     3001 ggattatccc tgatttccac tgcagcaaaa aaggcatcca tgtcaatatg gatgattttt
     3061 cttgacaaat catttaacaa aggaaaaatc aacatgccta gcaccttttt atactcttcg
     3121 aaaatctctt caaaccacgt cagctctatc tgcaacctca aaacagtgtt ttgagcaatc
     3181 tgcggctagc ttcctagttt gcttttcgat ttccattgag tgttactgct tattttcttt
     3241 tattataccc ttttttctga aaaaaagaaa aaaggacttt attttttcaa aaatataata
     3301 cagtttgaaa taaaatatag actgttttag aaaagaaagt gtaaaaatag ggaattttca
     3361 cttgttgaaa tcggttacta tatggtatac ttgtcttatg aatgtaacag atgactgtta
     3421 ctagaaaaaa gaggacatta atatggttgt taagacagtt gttgaagcac aagatatttt
     3481 tgacaaagct tgggaaggct tcaaaggcgt agattggaaa gaaaaagcaa gtgtatcacg
     3541 atttgtacaa gctaactaca caccttatga tggagacgaa agcttccttg caggaccaac
     3601 agagcgttca cttcacatca agaaaattgt agaagaaact aaagcacact acgaagaaac
     3661 tcgtttccca atggacactc gtccaacatc tatcgctgat atccctgctg gatttatcga
     3721 caaagaaaat gaagttatct tcggtatcca aaacgatgaa ctcttcaaat tgaacttcat
     3781 gccaaaaggt ggtatccgta tggctgaaac tactttgaaa gaaaatggat acgaaccaga
     3841 cccagctgtt cacgaaatct tcactaaata tgtaacaaca gttaacgacg gtattttccg
     3901 tgcctacact tcaaatattc gtcgcgctcg tcacgcacac actgtaactg gtcttccaga
     3961 tgcatactca cgcggacgta tcatcggtgt ttacgcacgt cttgctcttt acggtgcaga
     4021 ctacttgatg caagaaaaag taaatgactg gaatgcaatc aaagaaatcg atgaagaaac
     4081 aatccgtctt cgtgaagaag taaaccttca ataccaagca ttgcaacaag ttgttcgcct
     4141 gggtgacctt tacggggttg atgttcgcaa accagcgatg aacgtgaaag aagcaatcca
     4201 atgggttaac attgctttca tggctgtctg ccgtgtgatt aacggtgctg ctacatctct
     4261 aggtcgtgta ccaatcgtat tggacatctt tgcagaacgt gaccttgctc gtggtacatt
     4321 tactgaatca gaaatccaag aattcgttga tgatttcgtt atgaaacttc gtacagttaa
     4381 atttgctcgt acaaaagctt atgaccaatt gtactcaggt gacccaacct ttatcacaac
     4441 ttctatggct ggtatgggta acgacggtcg tcaccgtgtt actaagatgg actaccgttt
     4501 cttgaacact cttgacaaca tcggtaactc accagaacca aacttgacag ttctttggac
     4561 tgacaaattg ccatacaact tccgtcgcta ctgtatgcac atgagccaca aacactcttc
     4621 tatccaatac gaaggtgtaa caacaatggc taaagacgga tatggtgaaa tgagctgtat
     4681 ctcatgctgt gtgtctccac ttgatccaga aaatgaagaa caacgccaca acatccagta
     4741 cttcggtgct cgtgtaaacg ttcttaaagc ccttcttact ggtttgaatg gtggttacga
     4801 cgatgttcac aaagactaca aagtatttga tatcgaacca atccgtgacg aagttcttga
     4861 atttgaatca gttaaagcga actttgaaaa atctcttgac tggttgactg acacttacgt
     4921 agatgccttg aacatcatcc actacatgac tgataggtac aactacgaag ctgttcaaat
     4981 ggccttcttg ccaactaaac aacgtgccaa catgggattc ggtatctgtg gatttgctaa
     5041 cactgttgat acattgtcag ctatcaaata cgctacagtt aaaccaatcc gtgacgaaga
     5101 tggctacatc tacgattacg aaacaatcgg tgactaccca cgctggggtg aagatgaccc
     5161 acgttcaaac gaattggcag aatggttgat cgaagcttac acaactcgtc tacgtagcca
     5221 caaactatac aaagacgcag aagctacagt atcacttttg acaatcacat ctaacgttgc
     5281 ttactctaaa caaactggta actcaccagt tcacaaaggt gtatacctca acgaagatgg
     5341 ttctgtgaac ttgtctaaac ttgaattctt ctcaccaggt gctaacccat ctaacaaagc
     5401 taaaggtggt tggttgcaaa acttgaactc actttctagc cttgacttta gttatgcagc
     5461 tgacggtatc tcattgacta cacaagtatc acctcgcgct cttggtaaga ctcgtgatga
     5521 acaagttgat aacttggtaa caatccttga tggttacttc gaaaacggtg gacaacacgt
     5581 taacttgaac gttatggact tgaacgatgt ttacgaaaaa atcatgtcag gcgaagacgt
     5641 tatcgtacgt atctctggat actgtgtaaa cactaaatac ctcactccag aacaaaaaac
     5701 tgaattgaca caacgtgtct tccacgaagt tctttcaatg gatgacgcct tggatgcatt
     5761 gagctaatca agttcttgaa taataaaaag gaaccctcgg tcaaacgact gagggttttg
     5821 tgcttgggat agtatgagca attccttcgg cgcaatatgc aatgtttttg ggaaggaata
     5881 gtggaccgaa tctgaaatat aatagattga aactagaata gtacaccttt acttctaaaa
     5941 cattcttaga aatcgatttg actgtcctga tcgatttgtc ctattcttat ttcattttac
     6001 tatagtccgc tgaaacggct caaacagtgc tagaaattga ctggaattct ctaagtgatt
     6061 tgttccgatt ttatttcatt tcatcataaa aataagatga ctggctaatt gacaatcatc
     6121 ttgtttgata ctgttaataa aattcgcgaa gtttatcttg attttcttta aaaaattttt
     6181 ctaaccaatc cataccataa gcataactaa aaccttctaa tagaacagag aggtcaatag
     6241 tatcaaatcc catgtctttt aaatatttaa aggtatcgaa tggtgaatga aagtttttgt
     6301 atttaataat tgcaccaata tcttgcaaat cctgctctct gatactcatc atcttcattc
     6361 ctaacacata ctcaataggg actactaaaa cggtcagatt ctcaaatgag tacaaggatt
     6421 cgcataaact taagggaggt tgtttgttca tatttgcttt gcaacatgat tgttgagcca
     6481 taactcttcg tggatgttaa gattaaactg ttttcctaca cgagcaataa tttcattgat
     6541 tttctgattt tggtcataaa aagcatcaac atcttgtgtg gcacgtaaac catgatattc
     6601 taagacataa ccataattgt taaagtcaga ttttcctgaa ttaatttctt atttagggct
     6661 tggaagaccg gtttcatttt atccatgttt gtatttctcc atcaattttt gaacattggt
     6721 taacttagca ggtttattta atgaaatcac atatttatga gttggagtat gctcttgaaa
     6781 ggcatacttc aagctaattt tttgaaaacg ggttagttct ttggagtcta gcaacttttc
     6841 tacatcttgg tttgttaaat aagaatagtc ttcaaaaata acttttcgca aatagcgaaa
     6901 ccaatggctt gcgttgaatt gtgattgttt ggatgcctgt atcatataat cgtaccaatc
     6961 cattgtcttc ctcctataaa atttagttta tattattgta gtttatattc aaaaatgtag
     7021 tttttcttaa ttagctcgta tctataggat gatactgaaa atcttcttgt tgctttaaat
     7081 cacaatcgaa aaattctgtt tttcatctta gaaaagaatg tttagaaatg taaaatgaac
     7141 cttttttctt atccgaaaac cttactaaag tatataattt aggcagtcaa ttctgtatga
     7201 taatgtttgt actatcgtcg agtttttgct tgattgccta acgagataaa ttttagaaga
     7261 gttttcggtg tgatttgaca agtttctgac tggaaggata gttacactag tattgtttat
     7321 taaaatgagc agatagagaa aatttggaat ctatttgctt attatcaatc gtttttttag
     7381 cttatttgtc ttagattggt atagaactga gctatggatt aatcttcttc tatcttatcc
     7441 tgttcctaaa tatgttggta gaaaaatgaa gcagttgtta cgagtgtctg tattgggaaa
     7501 aattttgtct atagaattct ttaaatgata tgaaggctag gaatgccaaa acactgacat
     7561 atttcgttta aagtctatcc agtctcttca attgtatttg tagaaatgct atcagtaata
     7621 tattcgcgaa cactatgatt tacaacagtg tggtcgtaca tctttgtaac tttattatac
     7681 aacaaccatt tacaggtgta aagttgagca gtgtctttag taaatttagg gacttgtttt
     7741 gtcatagttt tgatacctgt attcgttgtt tcatgagcat ttgacgtttc ttttcatgta
     7801 ggcatttcaa caattagaat gatatttttc cgaggatgaa cttatatatt gtgacttttt
     7861 agagttatga tgcctcttga tttgactacc gctatcaatt tcatccactt ttacagtttc
     7921 atggttttat gaaccgaaac atctaggtac aggttttagc atcaattgat tgtttttgag
     7981 ccatatgaag ttgaaacgtg gagatgcttt tcttgtgata acgccctatt caaagaggaa
     8041 taaccgtttt tggagagagt tcagtactat gtggcgctaa atactatatg taaaacatat
     8101 attaaacaag atttaactaa ggagaattgt aaaaacaaaa atgagaattt catataaagt
     8161 ttattctagg agtatgtatc ttgaataaaa atcgttattt aagttcaggg ttatgatgaa
     8221 tgtttttata ataataaaat gcagctagaa gaaaagttat tttaatataa atcactcaac
     8281 atagagagaa ggcggtttcc tatatggaag tcgtcttgtt ttcatattgt ctaaatacga
     8341 gatatctact acaggttata gttgatttaa acaggtctat agatttctaa tatattaagg
     8401 tgaaataata tcttgtaata cattgctatg ttctatgaaa aaagcgacga tagctaatgc
     8461 acaagctcct atacttccac gatgtttgtt gtaaggtaaa atttcaattt ctatattacg
     8521 agtaaaggga acgaagtgga gctggtcttg gattttatcc ctgacttcat gagtgaaagg
     8581 ttgataatta agcaattgac tgttgatata gattttatca gcaggattga tgaggaggag
     8641 atttgcaata gaagtggcta ataaattgac tcctttatca atttgttgac gtaaagcgga
     8701 gtcgcctaaa ttataagccg ttaaaagggt gtctaaatga atgtcttttt cagtctttac
     8761 aaggcttttt agtacagtta gttgggaatt tttaaataat aattgggcgt gtttgattaa
     8821 ccaagcatcc gaaatatatg tttgtaaaca accttttttt ccgcattcac aatattgccc
     8881 attcaattcg acaatggtgt gtccaatttc tccgatataa ggatttttag aggctcctat
     8941 tttttctttt gtgaaaaagg aagtgtaaat acctaatcca gcgtgtagga aaataaagtt
     9001 atcgggggta ttgtgtggat taaaaaggta ttgtcctata gccatacaat cgatattatt
     9061 ttttacaata aaaggaaaat tgaatctttt aattacattt aataaattaa aagattccca
     9121 tatggggttg tttgtaatga tacttccgga gtctttgtta taatgtccag gtattgataa
     9181 gccaaatcca agtaattttg tttccaaagg gacgtactct atagctgttt ttatcatatt
     9241 ggtaatggtg gaattgattt ctgaaatagg ataatcttca ttcaaaattt ctgtctcgaa
     9301 aagagttttc ccttgtaagt cacatagact gagaaagata cctaggacgt ttatttcaat
     9361 acctccaaca acatacggaa tattatctgt gatagaaata gtttttctac gtcttccaga
     9421 tccggaaaac tcgctaaatt catcaccagt ttcgtatatg agggactgtt cgcttagctc
     9481 ttttatgatg ttagtcgttg ttgctggagt aagtcctgtt tcattaacaa tatctgtacg
     9541 ggatgttgct ggatttcgat atagaaactc cagtatagtg gctctatttt gtaaaaaggc
     9601 tgattgtttt gtaatcattt gtttcctcct ttggtttatt ttatattaaa cataagaaaa
     9661 aatcaattaa aattattatt ttatacaaag aaaaaaatat tgtaaaaaca acaaaaaata
     9721 tattgacaac gctttctgtt agtggtatat ttaatttata aaaaataaaa aaaggagttc
     9781 cggtgatgaa caatatttta gcgtttttag aaacaaaagt cgctccgttt ggtgaaaaag
     9841 ttggcaacca acggcatttg aaagctattc gtgaaggatt tatgatggca atgcctttga
     9901 ttttagtcgg atctttattt cttattctaa tcagttggcc tcaagaggat tttacaaatt
     9961 ggctgaatag tgttggattg ctaagtatct tgacaactat gaatcagtca acagtagcga
    10021 ttatctcctt ggtcgcttgt ttcggtattg cctacaggtt gtcggaagga tatggtacag
    10081 atggtccgtc ggcagggatc atagccttat ccagttttgt attgatggca cctcgttttt
    10141 cgagtatggt ttatgataaa aatggggagc aggtcaagca gttatttggc ggcgcaatac
    10201 cattttctag cctgaatgca tcttctttgt ttatggcgat tactattgga ttggttacag
    10261 cagagattta tcgtatgttt atccagcgcg gaattacgat aaaaatgcca agtggtgtcc
    10321 cagatgtggt aagtaaatca ttttcagctc ttttacctgg ctttactact tttgttttgt
    10381 gggctctggt cttaaaaggt cttgaagcgg caggagttgc aggaggtctc aacggactcc
    10441 taggtgcaat tgttggaaca ccgcttaagt taattgcagg aacgcttcca ggtatgattc
    10501 tatgtgttat tgtaaactca ttcttttggt tctgtggagt taatggggga caagttttaa
    10561 atgcttttgt agatccagtt tggttacaat ttactacaga aaaccaagaa gctgtggctg
    10621 caggacaaac actccaacac attattacat taccgtttaa agatttattt gtatttattg
    10681 gtggcggtgg agcgactatt ggtcttgcga tttgtctctt cctatttagt aagagtcgtg
    10741 cgaataaaac attaggtaag ctagctatta taccgtctat ttttaatatc aatacagcta
    10801 ttctatttac gtttccaaca gttttaaatc cgattatgct gattccgttt attgctactc
    10861 ctacaatcaa tgccttaatt acctatgtat caatggctgt aggattagta ccctacacaa
    10921 caggtgtaat ccttccgtgg acaatgccac cgatcatagg aggcttcctt gcgacaggag
    10981 ctagttggcg aggagctcta ttacaagttg ttttgatttt ggtttctgta gcaatttatt
    11041 atccattctt caaaattgca gataaacgca atcttgaaaa agaaaaagct actgttggag
    11101 ggaaataaga tggttatcag agtatttgat cagcagaaaa atacttattc tagctttgcc
    11161 ttagaggaat taagttacta tataaatcgg gtctttaaga ctgacataga acttgtcgag
    11221 gagaaggaag cggatatttt tgtaggatta gtcaataaag aggatagaaa agaccatgtt
    11281 cttatctcat tagacaaggg taaggggaga attgagtcta atacaattgt aggtttgctt
    11341 attggaattt accgaatgtt tcatgaattt ggggttgtgt atactagacc agggcgcgga
    11401 catgactttg ttccagagtt acgatttgaa gattttttag ataaagagct atctatagat
    11461 gaaacagcca gttactatca taggggagta tgtatagagg gagcagattc atttgaaaat
    11521 atactagatt tcattgattg gctacctaag attgggatga acagtttttt cattcagttt
    11581 gaaaatccct attctttttt gaaacgttgg tatgaacatg agtttaatcc atacctaaat
    11641 aaagaaaaat tctcaaatga attagtacaa gaattgagtg ataggttgga taaagaattg
    11701 caaaaaagag gtcttattca tcatcgtgtt ggtcatggat ggacaggtga ggttttaggt
    11761 tactcttcaa aatttggctg ggaatcaggt cttagtattt cagaggagaa gaaaccctat
    11821 gtcgctgaaa taaacgggaa acgagaatta tttaatacgg ctccgatttt aaccagtctg
    11881 gatttttcaa atccagatgt ggcggataag atggtagaaa ttatcaagga ttatgccaag
    11941 aaaagacctg atgttaacta cttacatgta tggttgtcgg atgctcgtaa taatatttgt
    12001 gaatgcgaaa actgtagaca agaattggtt tcggatcagt atattcgtat tctcaatcaa
    12061 ttggataggg ctttaacgag tgagggatta gatacaaaga tttgttttct gctttaccat
    12121 gagttgttat gggcgcctca gaaagaaaaa ttagataatc ctgaacgctt taccatgatg
    12181 tttgcaccga ttacaagaac atttgaaatg agttatgcag atgtagattt tgacaattcc
    12241 atacctacgc ctaaacctta tctgcgtaat aaaattatac ttccgaattc tcttgaggaa
    12301 aatttatctt atctttttga gtggcaaaaa acatttaaag gagatagttt cgtatatgac
    12361 tatcctttag ggcgtgctca ttatggcgat ttaggctata tgaaaattag tcaaaccatt
    12421 tacagagatg tatcttatct ttctaaccta catttgaacg gttacatttc gtgtcaagaa
    12481 ttacgtgccg gattccctca taattttcct aattatgtta tgggggaaat gctctggaag
    12541 aagacaagaa gttatgaaga attgattgaa gaatactttt ctgctttgta tgggtcaaat
    12601 tggcagtctg ttgttgaata tttagaaaaa ttatccagtt attcctcatg tgattatttt
    12661 aatgcaattg gcagtcgtca aaatgatgtt ttagcgaatc attattatat agcttacaat
    12721 ctagctgata attttttgcc aattattgag gaaaatattt ctaagttatt aaatagtcaa
    12781 aaggatgaat ggaaacagct cagttatcat cgtgaatatg ttgttaagat ggcgaaggct
    12841 ttatatcttc aagcaaccgg aaaaacaagg caagctcaag atgaatggag aaatgtgttg
    12901 aattatatcc gtgggcacga attgctattt caatctaatt tggatgttta tcgtgtaatt
    12961 gaagtagcaa aaaattacgc tggtttccac ttataaatca taagtataga aaatgaacca
    13021 aggtattcag agaagattga tcctaaatat tatgaaattt aaggattttt aagatattta
    13081 gggtcgactt tctatttata tcgtagcgaa gtcattttaa taatgatgtg taaaagatgg
    13141 atcaagattg aggaggaaga aagatgaaat caaaagaaga aataaatatg cttggtttta
    13201 caattgtcgc ttacgcagga gatgcaaggt cagatttgat ggatgctttg gcgtttgcga
    13261 gagatggata ttttgaacag gcaagagaat tggttgagtc tgcaaacgac tcaatagtgt
    13321 ctgcccatcg agaacagact aatttattag cggaggaggc atctggagat aattttgaag
    13381 tgagttttat catgattcat ggtcaagata ccttgatgac aacgatgcta ttgtatgatc
    13441 aggtcaagtt ttttattgat gaatatgaac gaattcgaaa gattgaagaa catattggtt
    13501 tgcaatgagg attagtcatg gaaaatttac aggttaaagc cttaccgaag gagtttttat
    13561 taggagctgc taccgctgct tatcaagtag agggtgcaac tagggtagat ggcaaaggaa
    13621 caaatatgtg ggatgtttat ttgcaagaaa acagtccgtt cttaccagat ccagctagtg
    13681 atttttatta tcgttacgaa gaggatataa ctttggcggc agaacatggt ttgcaggctt
    13741 tgcgtttatc tatttcttgg gttcgtatat ttcctgatat agatggggag cctaatatat
    13801 tagctgttcg ttattaccat agagtctttc agtcttgctt aaaacataat gtgattccgt
    13861 ttgtttcttt acatcatttt gattcgcctc agaaaatgtt agaaacaggg gattggttga
    13921 atagagagaa tattgatcgt ttcatacgat atgctcgctt ttgtttccaa gaatttacag
    13981 aagtcaagca ttggtttaca atcaatgaac tgatgtctct tgctgcaggt caatatatag
    14041 gaggtcagtt tcctccaaat catcattttc aattatctga agcaattcaa gcgaatcata
    14101 atatgttgtt ggcgcatgct cttgcagtcc tcgaatttca tcaattagga attgagggag
    14161 agataggttg tattcatgct ttaaagccag gctatcctat tgatgggcaa aaagaaaata
    14221 ttttggcagc taaacggtat gatgtttata ataataaatt tctattagat ggaacttttt
    14281 tgggctacta cagtgaggac acgctttttc acttgaatca aatattggaa gctaataatt
    14341 ctagctttat tattgaagat ggtgatttag aaattatgaa gagagctgca gctcttaata
    14401 cgatgtttgg gatgaattat tatcgttcag aatttattcg tgaatacaaa ggtgaaaata
    14461 gacaagaatt taattcaaca ggaataaaag gacagtcttc ttttaaatta aatgctctag
    14521 gtgaatttgt aaaaaaacct ggtattccga caacagattg ggattggaat atttatcctc
    14581 aagggttatt tgatatgttg cttcgtatca aagaagaata tcctcaacat ccggtcattt
    14641 atttaactga aaatggtaca gcccttaaag aagttaagcc agagggcgag aatgatatta
    14701 ttgatgacag taagagaatc cgttatattg agcaacattt acacaaagtt ttagaggctc
    14761 gagatagagg agtcaatatt caaggctatt ttatatggtc tttgcaagat caattttctt
    14821 gggcgaatgg ctacaataag cgatatggtc ttttctttgt tgattatgaa acacagaaga
    14881 gatatattaa gaaaagtgct ctttgggtaa aagggctaaa acggaattaa ggttagcgat
    14941 ttgactgatg tttaatatat tttaactatg agcttaaatt ttttacagga ggagttttta
    15001 tggataagtt agtcgctgcc attgaaaagc aacaagggaa atttgaaaaa atttctacta
    15061 ataattatat gatagctatt aaagatggat ttattgctac tatgccttta attatgtttt
    15121 caagcttttt gatgattatt attatgattc ctaaaaattt cggagtagag ttaccgagtc
    15181 cagctattgc ctggatgagg aaagtgtata tgctaaccat gggagttttg ggtattattg
    15241 tttcagggac agttgcaaag tcattggctg gaaatgttaa tagaaaaatg cctcctggaa
    15301 aggtaataaa tgatacttct gcaatgttgg cggccatatg tggctatctt gtattaactg
    15361 taacgcttgt agttgatgag aaaacgggat ctacaagttt gtcgacaaac tatttaggat
    15421 ctcaaggatt gataacttcg tttgtcagtg cctttattac tgtaaatgtt taccgattct
    15481 gtattaagcg agacattact attcatttac ctaaggaagt tcctggggct atatcacaag
    15541 cttttagaga tatttttcct ttttcttttg ttttacttat tagtggtttg ttagatattg
    15601 tatctcggtt tagtttagat gttccttttg cccaagtatt tcaacaacta ttgactccta
    15661 tttttaaggg ggcagaatca tatcctgcta tgatgttgat ttggtttatg tgtgctttgc
    15721 tttggtttgt tggaattcat ggaccatcta ttgtcttacc tgctgttaca gctttacaac
    15781 tgagcaatat ggaagagaat gctcaacttc ttgcaaatgg gcagttccct tatcattctt
    15841 taacacctaa tttcgggaat tatatcgctg ctattggagg aacgggggct acctttgttg
    15901 taccatttat tttgattttc tttatgcggt ctaaacaatt aaaatcggta ggtaaagcta
    15961 caattactcc tgttttattt gcggtaaatg aacctcttct atttggtatg cctgttattt
    16021 tgaatcccta tctttttgtc ccttttttga tgactccacc agtgaatgta tttctaggaa
    16081 aggtatttat tgatttcttt ggaatgaatg gattttatat ccagttacct tgggcctttc
    16141 ctggtccctt gggattgtta attggaacga attttcaact tatctccttt gtatttttat
    16201 ctttgatgtt agttgtcgac atattgattt atttgccatt ctgtagagcg tatgatagac
    16261 agttactggt gaaagaagat attgcaagct caaatgatat tattttagag gaggatacaa
    16321 gtgaaataat gcctggtgag atagatgtaa taaaaagtaa ggagttgaaa gtactggttc
    16381 tttgtgcagg gtctggaaca agtgcgcaat tagccaatgc aattaacgag ggcgctcaat
    16441 tagcagaagt tagagtgatt gcgaattcag gagcgtacgg agctcattat gatattatgg
    16501 gtgtttatga tttaattatt ctggccccac aagttcggag ttattataga gagatgaagg
    16561 tggatgcaga aagattagat attcagatag ttgctaccag aggaatggaa tatattcatt
    16621 taacaaagag tccaagtaaa gccttacaat ttgtattgga gcattaccaa gctgtgtagt
    16681 aagtttttcc atcttttatt tgagtaaaga ttttgcttac agataggctt ggatttaaaa
    16741 acgttccccc ttttttaata taagaatccc tctttcacaa ttgtaaaaag agggattttg
    16801 tattttatct cttagaccaa gttctcttca taaagagaag gaggattggg taaatctcca
    16861 agcgccctgc aatcattgca aaggatagga gaatttttga gatgggacta aagattgaga
    16921 aactagaagt ggttcctaga ataggcccga tattattgaa acagctaaag acagcgctgg
    16981 tcacgaccag aaaatcattg ctatctaggc tgacaataaa gataagcgct agcaaaatca
    17041 tagcatagat gacaaagtac ttgagaatct tatgctgggt atctttgtca atcaccgttt
    17101 tattaacatg gagggtcaaa acacggtggg gcgataggat tgacaaaatt tggtttttgg
    17161 caatttttga aaggatgagg cctcgaataa tcttgagtcc acctgcagtt gatccagcag
    17221 agccaccgat tgccatgagg aaaaggagga taaactggga gaagaggggc cagttggtaa
    17281 tatctccata tccaaaacca gttgttgtaa tgatgttgga aacctggaag aaggtcattt
    17341 caaagctctt tgaaaaccct gggtagaggt agagggtgtt gaggctaatc aagcctgtag
    17401 aaaccagtac aatgaccaag taagccctaa gctcttcatc tccaaagaag gccttgatgc
    17461 gacggagcat gaggtagtag tagaggttga aatttactcc aaaaaccaga actccgatac
    17521 tgaccagata ggtaatcagt gagctgccat agtgggcaat tccgtcgtta tagacggtaa
    17581 agcctccagt tcccgctgtc cccatagcaa tgacaaaact atcgtagaga ggcataccag
    17641 ctagataata gatgatgaca aagagggaga agagagctag ataaaggaga tagagaatct
    17701 gggcagtgtt ttttagtttg gatacaacct tgccaaaaac aggacctgga acctcagcct
    17761 tcatcacctc taggtggcta tttttggcat tgtccataat agcaagtgca aaaacaagca
    17821 ctcccatccc tccaatcaag tgggtaaaac ttcgccagaa gaggagggaa cgactgagaa
    17881 ctgaaacgtc gttcaaaata cttgctccag tagtcgtaaa gccggaacta atctcaaaaa
    17941 aggcatcaat aaggctgggg atttgcccag aaaagacaaa ggggagacca ccaaagaaag
    18001 accaaaggat ccaacagagg gcaacgatca agactccctc cttggcataa atccgttgat
    18061 tttttggctt ctgtaaactc cctgaaccgc ctaacaatac gagaatccct atggtcgaaa
    18121 agagggctgt aaagacttgg ctcgattcac ggtaatagac agcgatagcc acaggaacca
    18181 agaggagaac agcttcaatc aaaagtaact ttgaaaggag gtaacgaatc atacttttat
    18241 tcatttctta cctcgcaatc aagtcataaa tcttggtgat gtttggcaac aaggttgtta
    18301 ctaggagctt gtctccaact tccaacatat cctccccagt tgggaaaata gtcttgccct
    18361 ttcgaataat ggctgcaata agaacccctt ttttcaattt cagttgagaa agaggtttgg
    18421 cagtcatttt attggcttcc ttgatatgga attgcagggt ttcgatttgg ccattggcta
    18481 gatggtgcat ggcttgaagg tctgaatact gggcattaac tcgaccacga ataaagtgca
    18541 taatcgtatc tacagcgatg cttttaggtg tgatgatact tgaaaaatca ggcgcattga
    18601 taatctcgag gagactggta cgattgacct tagtaatatt tttctgtaca cctaccctgt
    18661 caaggaacat agatgtaatc agattttcct catcgactcc tgttagagtc gcaacggcat
    18721 catagtgttg agcactttct tccagcagga tatcttttgc ggttccatct ccttgaacga
    18781 tgtagagatt tgggaatttc tcgctaaaga agctggcgat ttcaggattg atttcaatga
    18841 cttttgtatc gatacgacta tctttgagaa taccaagtag ataataggca attctacctg
    18901 ccccaacgat gagaaggctc ttcacggcgc gtgatttaaa ataattatgg aagagtatca
    18961 tatcgacacg gttaccagtg acaaagattc tatctttatc ctgtacagtc atgtcaccgc
    19021 ttggaatgat aatttgatga tccctctcta tcgcacagac aatgacatta ccaaattttt
    19081 tacgaaaatc agaaatgggc atttggcaaa gaccgctggt ggacttgacg acaaattcca
    19141 tgaggctaac gcgtccacca gcaaagcgtt cgacagacag ggcgttgggg aagtcaatga
    19201 tattcgcgat agcacgggca gccaagagct caggattaac gataagagaa aaaccgagaa
    19261 tattcttttc cttgaaataa gagttagaat attcagggtt ccgcacccga acgatagttt
    19321 ctttagctcc cattttcttg gctagaactg ctgcaatcat gttgacttca tcgtgctcag
    19381 tcagggcgat aaagatatca caatcttgga cgctggcttg ctcaagaatg gcaaaatcgg
    19441 ccccgttacc aaggatacca atgatatcaa agcgactgac aatatgattg agaacagctt
    19501 cgtcttgctc aatcagcaaa acatcatgct tttctgcaac caaggagcga cagagggcaa
    19561 aaccaacttt tccccctccg acaaggataa ttttcataat aaaacctact ttttcatgat
    19621 gtaactatca tacccttttt caagaaaaaa tgcacctact agctaataac aagagctttt
    19681 agtgaaaatt cgctataaga taaaactata ccctaaccaa ttgaaatagc tattagcgac
    19741 tttctctgaa atatggtatg ataaaggata tacaaggaga taaaatgaat aataatttac
    19801 tggtattaca atcagacttt ggtctggttg atggtgcggt atcggctatg attggagtgg
    19861 ctttagaaga gtctccaacc ttaaaaatcc atcacttgac gcacgatatc acgccttata
    19921 atatttttga ggggagctat cgtctctttc agacggtgga ttactggcct gagggaacga
    19981 cgtttgtatc ggttgtcgat ccaggtgtcg gttcgaaacg taagagtgta gttgccaaga
    20041 ctgcaaaaaa tcaatacatt gtcacgccag ataatgggac gctttccttt atcaagaaac
    20101 acgttggcat tgtagccatt cgtgagattt ctgaggtggc caataggcgt caaaacacag
    20161 agcattctta taccttccac ggtcgtgatg tctatgccta tactggtgct aaactggcca
    20221 gtggtcacat tacttttgag gaagtagggc cagagctcag tgtggaacag attgtagagc
    20281 ttccagtcgt agcgaccatc atagaagatc atctggtgaa gggagccatt gatattctgg
    20341 atgtgcgttt cggttcgctt tggacctcta tcacacggga agaattttac aagttggaac
    20401 cagaatttgg tgatcgtttt gaagtgacca tctatcatgc tgatatgctg gtctatcaaa
    20461 atcaggttgt ctatggcaaa tcatttgcag atgtgagaat tgggcaaccc atcctttaca
    20521 tcaactctct ctatcgttta ggtttggcta tcaaccaagg ttcctttgcc aaggcctata
    20581 atgtaggtgt cggttcatct tggaccattg aaataaagaa aatagaagga taaaatagga
    20641 gaatagtatg gaaatcaaat ttacaattaa acaagttgtt gctgtcggaa ttggcgctgc
    20701 cctctttgtc gtcatcggga tgatcaacat tccaacccct gttccaaata caagcatcca
    20761 gcttcagtat gcggtacaag cgctactttc tattattttt ggaccgatta tcggtttgct
    20821 tgttgggttg attggtcatg caatcaagga ctctcttgtt ggttatggtc tatggtggac
    20881 ttggattatc gctagcggac tctttggttt agttgtggga ctttttagaa agtacgttcg
    20941 cgtgatcaat ggtgtttttg actggaaaga tattcttatt tttaacctca ttcaactact
    21001 tgcaaatgcc cttgtttggg gtgtcttggc accacttgga gatgttgtga tttatcaaga
    21061 agcggcagaa aaagtatttg cacaaggaat tgttgcggga attgccaatg gtgtatctgt
    21121 agctattgca ggaactcttc tcttacttgc ctatgcagga acccaaactc gtgcaggaag
    21181 tttgaaaaag gactaatact caatgaaaat caaagagcaa actaggaagt tagccgcagg
    21241 ttgctcaaaa cagtgttttg aaattgtgga ta
//
LOCUS       DAVBDR010000036        21102 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.036, whole genome shotgun sequence.
ACCESSION   DAVBDR010000036 DAVBDR010000000
VERSION     DAVBDR010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21102)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21102)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21102
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.036"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            <1..266
                     /locus_tag="VQ540_001346"
     CDS             <1..266
                     /locus_tag="VQ540_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HET2545144.1"
                     /translation="SIDERLRTRLRVIIWKQWKKKSRRLWGLLKLGVPKWIADKVSGW
                     GDHYQLVAQKSVLKRAISKPVLEKRGLVSCLDYYLERHALKVS"
     gene            720..1413
                     /locus_tag="VQ540_001347"
                     /pseudo
     CDS             720..1413
                     /locus_tag="VQ540_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809626.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
     gene            1469..1741
                     /locus_tag="VQ540_001348"
     CDS             1469..1741
                     /locus_tag="VQ540_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase"
                     /protein_id="HET2545145.1"
                     /translation="MFLLFSALVGMLSQLKEVPESVFLQETVEENHLVNVYSVLEVIS
                     TLAFSVFVLLMSYITESFGISISFWLSAICLMIEAILIYIRRDYFK"
     gene            2055..2186
                     /locus_tag="VQ540_001349"
     CDS             2055..2186
                     /locus_tag="VQ540_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HET2545146.1"
                     /translation="MKQRKELYLFLGRTALYFLIFLGLLYFFSYLGQGQGSFIYNEF"
     gene            2207..3757
                     /gene="dltA"
                     /locus_tag="VQ540_001350"
     CDS             2207..3757
                     /gene="dltA"
                     /locus_tag="VQ540_001350"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012972622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HET2545147.1"
                     /translation="MSNKPIADMIETIEHFAQTQPSYPVYNVLGQEHTYGDLKADSDS
                     LAAVIDQLGLPEKSPVVVFGGQEYEMLATFVALTKSGHAYIPIDSHSALERVSAILEV
                     AEPSLIIAISAFPLEQVSTPMINLAQVQEAFVQGNNYEITHPVKGDDNYYIIFTSGTT
                     GKPKGVQISHDNLLSFTNWMIMDKEFATPSRPQMLAQPPYSFDLSVMYWAPTLALGGT
                     LFTLPSVITQDFKQLFAAIFSLPIAIWTSTPSFADMAMLSEYFNSEKMPGVTHFYFDG
                     EELTVKTAQKLRKRFPNARIINAYGPTEATVALSAVAVTDEMLATLKRLPIGYTKADS
                     PTFIIDEEGNKLPNGEQGEIIVSGPAVSKGYMNNPEKTAEAFFEFEGLPAYHTGDVGT
                     MTDEGLLLYGGRMDFQIKFNGYRIELEDVSQNLNKSRFIESAVAVPRYNKDHKVQNLL
                     AYVILKDGVREQFERDIDITKAIKEDLTDIMMSYMMPSKFLYRDSLPLTPNGKIDIKG
                     LINEVNKR"
     gene            3754..4998
                     /gene="dltB"
                     /locus_tag="VQ540_001351"
     CDS             3754..4998
                     /gene="dltB"
                     /locus_tag="VQ540_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HET2545148.1"
                     /translation="MMEFFQQLPHLEPYGNPQYFVYVIAATLPIFIGLFFKKRFAWYE
                     VLVSLFFIVTMLVGGKTNQLAALGIYLCWEILLLLFYKHYRKSKDGKWVFYLVSFLSL
                     LPIIFVKVQPAINGTQSLLGFLGISYLTFRSVGIIIELRDGVIKDFTLWEFLRFLLFM
                     PTFSSGPIDRFKRFNENYQAIPERDELMDMLDESVRYIMWGFLYKFILAHVLGETLLP
                     PLKNLALQSGGFFNLYALAVMYTFGLELFFDFAGYSMFALAISNLMGIRSPINFNKPF
                     LSRDLKEFWNRWHMSLSFWFRDFVFMRMVMVLTRKKVFKNRNVTSSMAYIVNMLIMGF
                     WHGVTWYYIAYGLFHGLGLVINDAWVRKKKTLNKERKKAGKAALPENRWIQLLGMVVT
                     FHVVMLSFLIFSGFLNNLWFKK"
     gene            5012..5251
                     /gene="dltC"
                     /locus_tag="VQ540_001352"
     CDS             5012..5251
                     /gene="dltC"
                     /locus_tag="VQ540_001352"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005591431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HET2545149.1"
                     /translation="MDIKSEVIEIIDELFMEDVSDMMDEDLFDAGVLDSMGTVELIVE
                     IENRFDIRVPVTEFGRDDWNTANKIIAGIVELQNA"
     gene            5244..6512
                     /gene="dltD"
                     /locus_tag="VQ540_001353"
     CDS             5244..6512
                     /gene="dltD"
                     /locus_tag="VQ540_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000919885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HET2545150.1"
                     /translation="MLKRLWMIFGPVLIAGLLVFLLIFFYPTEMHHNLGAEKRSAVAT
                     TIDSFKERSQKVRALSDPNVRFVPFFGSSEWLRFDGAHPAVLAEKYNRSYRPYLLGQG
                     GAASLNQYFGMQQMLPQLENKQVVYVISPQWFSKNGYDPAAFQQYFNGDQLTSFLKHQ
                     SGDQASQYAATRLLQQFPNVAMKDLVQKLASKEELSTADNEMIELLARFNERQASFFG
                     QFSVRGYVNYDKHVAKYLKILPDQFSYQAIEDVVKADAEKNTSNNEMGMENYFYNEQI
                     KKDLKKLKDSQKSFTYLKSPEYNDLQLVLTQFSKSKVNPIFIIPPVNKKWMDYAGLRE
                     DMYQQTVQKIRYQLESQGFTNIADFSKDGGEPFFMKDTIHLGWLGWLAFDKAVDPFLS
                     NPTPAPTYHLNERFFSKDWATYDGDVKEFQ"
     gene            6667..7107
                     /gene="adcR"
                     /locus_tag="VQ540_001354"
     CDS             6667..7107
                     /gene="adcR"
                     /locus_tag="VQ540_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent transcriptional regulator AdcR"
                     /protein_id="HET2545151.1"
                     /translation="MRQLAKDINAFLNEVILQAENQHEILIGHCTSEVALTNTQEHIL
                     MLLSEESLTNSELARRLNVSQAAVTKAIKSLVKEGMLETSKDSKDARVIFYQLTDLAR
                     PIAEEHHHHHEHTLLTYEQVATQFTPNEQKVIQRFLTALVGEIK"
     gene            7107..7811
                     /locus_tag="VQ540_001355"
     CDS             7107..7811
                     /locus_tag="VQ540_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HET2545152.1"
                     /translation="MRYITVEDLSFYYDKEPVLEHINYCVDSGEFVTLTGENGAAKTT
                     LIKASLGILQPRIGKVAISKTNTQGKKLRIAYLPQQIASFNAGFPSTVYEFVKSGRYP
                     RKGWFRRLNTHDEEHIKASLDSVGMWEHRDKRLGSLSGGQKQRAVIARMFASDPDVFI
                     LDEPTTGMDAGSKNEFYELMHHSAHHHGKAVLMITHDPEEVKDYADRNIHLVRNQDSP
                     WRCFNVHENGQEVGHA"
     gene            7804..8610
                     /locus_tag="VQ540_001356"
     CDS             7804..8610
                     /locus_tag="VQ540_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HET2545153.1"
                     /translation="MLSLLSYDFIQRAFLAVIAMSLFSPVLGTFLILRRQSLMSDTLS
                     HVSLSGVAFGLVLGISPTVSTIAIVLIAAVFLEYLRTVYKSFMEIGTAILMSTGLAVS
                     LIVMSKGRSSSSMSLDQYLFGSIVTISEEQVISLFVIAAVVLILTFLFLRPMYILTFD
                     EDTAFVDGLPVRTMSILFNMVTGVAIALMIPAAGALLVSTIMVLPASIALRLGKNFKS
                     VMLLASAIGFLGMVAGLYISYYAETPASASITIIFVTVFILISLVRRFIK"
     gene            8620..10125
                     /gene="adcA"
                     /locus_tag="VQ540_001357"
     CDS             8620..10125
                     /gene="adcA"
                     /locus_tag="VQ540_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding
                     lipoprotein AdcA"
                     /protein_id="HET2545154.1"
                     /translation="MKKISLLLASLCALFLVACSNQKQADGKLNIVTTFYPVYEFTKQ
                     VAGDTANVELLIGAGTEPHEYEPSAKAVAKIQDADTFVYENENMETWVPKLLDTLDKK
                     KVKTIKATGDMLLLPGGEEEEGDHDHGEEGHHHEFDPHVWLSPVRAIKLVEHIRDSLS
                     ADYPDKKVTFEKNAAAYIEKLQALDKAYAEGLSQAKQKSFVTQHAAFNYLALDYGLKQ
                     VAISGLSPDAEPSAARLAELTEYVKKNKIAYIYFEENASQALANTLSKEAGVKTDVLN
                     PLESLTEEDTKAGENYISVMEKNLKALKQTTDQEGPAIEPEKAEDTKTVQNGYFEDAA
                     VKDRTLSDYAGNWQSVYPFLEDGTFDQVFDYKAKLTGKMTQAEYKAYYTKGYQTDVTK
                     INITDNTMEFVQGGQSKKYTYKYVGKKILTYKKGNRGVRFLFEATDADAGQFKYVQFS
                     DHNVAPVKAEHFHIFFGGTSQEALFEEMDNWPTYYPDNLSGQEIAQEMLAH"
     gene            complement(11245..12018)
                     /locus_tag="VQ540_001358"
     CDS             complement(11245..12018)
                     /locus_tag="VQ540_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HET2545155.1"
                     /translation="MIKDERVLELIEIIKKKKRIAVKELAEITFSSTSTLRRDLIFLE
                     NQGLIKRKHGYVTLSSMNTIELSHQIREGESTRQKRLIASLAKDFIRSGMCIYLDSST
                     TVYELCPYLSELDNLIIFTNGLHTAQTLSETVKDSSKIFITSGEVKHQSCSVVNYDKE
                     NSLLDHFNIDLAFCSARGIDDQYVYEASLSQAISKKNIIDKAHETILLIDSSKFYKTG
                     FFKINPLSKYTTFISDTLPDQKLLDAVELFDGEWVSDIQ"
     gene            12194..13597
                     /locus_tag="VQ540_001359"
     CDS             12194..13597
                     /locus_tag="VQ540_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase"
                     /protein_id="HET2545156.1"
                     /translation="MEAVLAIDLGATSGRAIVGYLSENKLVMEEINRFSNLPIRVKGH
                     LSWDIDFLLAKILESIRLANTSYKILSIGIDTWGVDFGLIDNEGKLLSQPVHYRDERT
                     KGVLKEISEMTELEKLYSETGNQIMEINTLFQLFKARQESPDSFYKTNKILLMPDLFN
                     YLLTGKFATEKSIASTTQLFDPRSQNWNQNILKLFELDSSLLPEIVSEGNVLGRIKKE
                     YGLGDIPVVNVCSHDTASAIVSVPKTEGSLFISSGTWSLVGVELTSPILTTESFSYGF
                     TNEVGKDGVITFLKNCTGLWIIEELRRSFERRGKAYSFDDIRTMVEKEKENLPLIDTE
                     STEFATESDMHKTLTEYLAYHHETREWTDGQLFKIVYESLAETYRKAIELLEELTHKV
                     YKRIYVIGGGARASYFNQMIADRTGKEVLTGLTEATAVGNIVVQLIAMGQLKGMEEAH
                     HVIEEFLQLESYYSQKN"
     gene            13712..14350
                     /locus_tag="VQ540_001360"
     CDS             13712..14350
                     /locus_tag="VQ540_001360"
                     /EC_number="4.1.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001286141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fuculose-phosphate aldolase"
                     /protein_id="HET2545157.1"
                     /translation="MSDVKQELIKYGKKLVETDLTKGTGGNLSVFDREKQLMAITPSG
                     IDFFEIKESDIVVMDINGNVVEGERLPSSEWYMHLIQYQTRDDIDAIIHAHTTYATVL
                     ACLREPLPASHYMIAVAGKDVRVAEYATYGTKELAVNAAKAMEGRRAVLLANHGILAG
                     AQNLLNAFNIVEEVEYCAKIYCLAKNFGEPVVLPDEEMELMAEKFKTYGQRK"
     gene            14362..14802
                     /locus_tag="VQ540_001361"
     CDS             14362..14802
                     /locus_tag="VQ540_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000912112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RbsD/FucU family protein"
                     /protein_id="HET2545158.1"
                     /translation="MLKHIPKNISPDLLKTLMEMGHGDEIVLADANYPSASCANKLIR
                     CDGVNIPELLDSILYLMPLDSYVDSSIQFMNVVSGDDIPKIWGTYRQMIEGHGTDLKT
                     ITYLRREDFYERSKKAYAIVATGETSLYANIILKKGVVVERENV"
     gene            14795..15226
                     /locus_tag="VQ540_001362"
     CDS             14795..15226
                     /locus_tag="VQ540_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000483177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET2545159.1"
                     /translation="MFNRGILVASHGDFASGALMTAEMFVGETTNDRVRTLGLMPGEN
                     IVEFEHYFKNQVDELLDSNQEVIVLTDLIGGSPNNVALSRFLNLDSVDIVTGFNIPLL
                     VELISNYDSKINLEEIVHNAQNSLFNVKQQLNVEEEENLCL"
     gene            15217..15687
                     /locus_tag="VQ540_001363"
     CDS             15217..15687
                     /locus_tag="VQ540_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000020992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET2545160.1"
                     /translation="MSIEFVRIDDRLVHGQVVTTWLKKYDIEQVIIVNDRISEDKTRQ
                     SILKISAPVGLKIVFFSVKRFVEVLNSVPIKKRTMLIYTNPKDVYDSIEGNLKLEYLN
                     VGQMSKTEENEKVTGGVALGEEDKYYFKKIVDKGTRVEIQMVPNDKVTMLEKFL"
     gene            15712..16485
                     /locus_tag="VQ540_001364"
     CDS             15712..16485
                     /locus_tag="VQ540_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000899624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HET2545161.1"
                     /translation="MLFTQALLVTLVGIIATIDYNGPLFMIHRPLVTSAMVGLVLGDF
                     TQGVLIGSALELTWLGVTGIGGYTPPDTISGAIIGTAFGILSGQGETAGIAIAVPIAV
                     ATQQLDVLAKTLDVYFVKKADNDAKNGDYSKIGFYHYSSLVLITLFKIVPIFLAIMLG
                     GEYVADLFAKVPPIVMQGLNSAGALLPSIGFGMLLNMMLKKNMWVFLLIGFICSVYGG
                     MSTIGISLVGIAVAYFYDMIGSKPQETTSSSDVEEDLDL"
     gene            16482..17282
                     /locus_tag="VQ540_001365"
     CDS             16482..17282
                     /locus_tag="VQ540_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HET2545162.1"
                     /translation="MMNNKVTKVELKKVFKRSFMYGSSWNYERMQNLGFLYTILPVLK
                     KLYPDKDSASPAMKRHLEFFNTHQTAAPFILGVTSAMEEQEGNEGAASITGIKVGLMG
                     PLAGLGDSLFWLTLVPICFSIGASYSKDGGALGIFIALILFNIINIPVKYFGLKYGYT
                     KGSSLIQENNTKGTLNRVTSMATALGLVLVGGLIPSMVGINFGLEFKQGELVISVQEM
                     ITKLIPGFIPMALTLLMCKLIRKGKNPVVLIFSVMAIGVILVVLGILK"
     gene            17341..19635
                     /locus_tag="VQ540_001366"
     CDS             17341..19635
                     /locus_tag="VQ540_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HET2545163.1"
                     /translation="MKLWYKKAASNWNEALPIGNGHLGGMIYGSATKECIQLNDETIW
                     YRGKSDRNNPDSLLHLKKIREYLLDGEIQKAEELIKLTMFATPRDQSHYELLGELYIE
                     HIDIQSCALSLYERELDLDTAISNVVFEPNSCNLQIKREYFTSFNKNILCCRIVSSVQ
                     NTLNLNINLGRNKRFNDEVSKLDSSTILMSASAGGRKGVQFKVVCHSKVTDGEVSVLG
                     ETIVIRNATEVFLYLKSMTDYWGNIDISSLQGEFSSIDYFTEKDEHVKKYQEQFNRVD
                     FKLDYSKDCLSIPTNLLLENTKKYSNYLTNLLFHYGRYLLISSSQPNGLPVNLQGIWC
                     DELNPIWGSKYTININTQMNYWMVGPCDLPEVEYPLFDMLERMREPGRLTAKKMYGAR
                     GFTAHHNTDGFGDTAPQSHAMGAAIWVLTIPWLCTHIWEHYLYFQDERILTEHFEMIK
                     EAFLFFEDYLFEVDGYLMTGPSVSPENKYRLKNGIEGNACLSSTIDNQILRYFCDSCI
                     GIAKQLGDNSDFISRVKELKKKLPKTKIGSNGQIQEWLEDYEEVEPGHRHISPLFGLY
                     PYNEIDIHKTPELAEAAKITINRRLSNANFLSSQEREQAINNWLVSGLHASTQTGWSA
                     AWLIHFFARLYQGEPAYNQINGLLNNATLGNLFLDHPPFQIDGNLGLVSGICELLVQS
                     HHNWLSLIPALPSAWSEGEVKGFRVRGGYKVSFAWKNGDITFLKLEGGNKDQKVRVRI
                     YGKNTDVQNIELVFNSEKIIELNF"
     gene            19645..>21102
                     /locus_tag="VQ540_001367"
     CDS             19645..>21102
                     /locus_tag="VQ540_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001031112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2545164.1"
                     /translation="MNKEKIKRKLITILFVCIGMLCFGLLAGVKADNRVQMRTTINNE
                     SPLLLSPLYGNDNGNGLWWGNTLKGAWEAIPEDVKPYAAIELHPAKVCKPTSCIPRDT
                     KELREWYVKMLEEAQSLNIPVFLVIMSAGERNTVPPEWLDEQFQKYSVLKGVLNIENY
                     WIYNNQLAPHSAKYLEVCAKYGAHFIWHDHEKWFWETIMNDPTFFEASQKYHKNLVLA
                     TKNTPIRDDAGTDSIVSGFWLSGLCDNWGSSTDTWKWWEKHYTNTFETGRARDMRSYA
                     SEPESMIAMEMMNVYTGGGTVYNFECAAYTFMTNDVPTPAFTKGIIPFFRHAIQNPAP
                     SKEEVVNRTKAVFWNGEGRISSLNGFYQGLYSNDETMPLYNNGRYHILPVIHEKIDKE
                     KISSIFPNAKILTKNSEELSSKVNYLNSLYPKLYEGDGYAQRVGNSWYIYNSNANINK
                     NQQVMLPMYTNNTKSLSLDLTPHTYAVVKENPNNLH"
BASE COUNT         6542 a         3448 c         4467 g         6645 t
ORIGIN      
        1 ccagcataga tgagcgcttg cgtactcgcc tacgagtgat tatctggaag caatggaaga
       61 agaaatcgag acgattatgg ggattgctta agttaggagt tcctaaatgg atagcagata
      121 aggtatctgg ctggggcgac cattatcaat tagtagctca gaagtcggta cttaaacgtg
      181 ctatatcaaa accagtcctg gaaaaacgtg gactggtttc gtgtttggat tattaccttg
      241 aacgacatgc gttaaaagtt agttgaaccg ccgtatgccg aacggcacgt acggtggtgt
      301 gagaggggct agagattatc ctctactcga ttaactcccc tgaaatttgt tttaattatg
      361 caaatttcac gtatttttga tgctgagacg acgatcctgg gaacttttca gatatttttt
      421 tgactatcta aaatctatca ttagaaaagc ttagagcgcc aaaggatttg agcgtttttc
      481 tgatttttaa gactttttcc cagtctcttt ttcgattgaa gatgtaatta ttctactaac
      541 taacttctta gtactagcca acaacgataa tcataattcc tcctaaaatt aggaataata
      601 aaggcaatag tttttgtttt ttcatgtaaa aaacctcact tttgttttct gctattttat
      661 gctaaaatat taaaaatcaa atttaattcc aaagtttgta actaaagggg gagcgctaca
      721 tgtctaattc atttgtcaag ttgttagtct ctcaattatt tgcaaattta gcagatattt
      781 tctttagagt aacaatcatt gctaacatat acattatttc aaaatcagta attgccacat
      841 cactagttcc tatcttaata ggaatatcct cttttgttgc gagtctttta gttccgttgg
      901 ttactaaaag gttagcgcta aatagggttt tatctttatc tcaatttgga aagactatat
      961 tattggcgat actggtagga atgtttaccg taatgcaatc cgtagcgcct ttggtgacct
     1021 atctatttgt tgttgcaatt tccatactag atggttttgc agcacccgtt tcctatgcta
     1081 ttgtgccacg ctatgcgacc gatttgggta aggctaattc agccttatca atgactggtg
     1141 aagctgttca attgataggt tggggattag gtggactctt gtttgcaaca attggtctgt
     1201 tacctaccac gtttatcatt ttagtcttgt atatcatttc tagctttctg atgttatttc
     1261 ttcctaacgc tgaagtggag gtgttagagt cagaaactaa tcttgaaatt ttgctcaaag
     1321 gttggaagtt agttgctaga aatcctagat taagactttt tgtatcagca aatttattgg
     1381 aaattttttc aaatacgatt tgggtttctt ccattttgta gctatggcaa tagtgacact
     1441 gactattcta tattttccaa acgcacagat gtttttatta ttttcagctt tagttggtat
     1501 gttatcgcaa ctaaaagaag ttcctgaaag tgtatttctt caggaaacag tagaggaaaa
     1561 tcatttagtt aatgtctatt ccgttcttga agtgatttct acattagcat tttcagtatt
     1621 tgttttgcta atgagctata ttactgagag ttttggtatt agcatcagtt tttggctatc
     1681 agccatttgt ctgatgatag aagctatttt aatttatatc agacgagatt attttaaatg
     1741 agagagtggt taaaaagtct ttaaaaatca gaaaagcgca tagtatcagg tgttgaaaaa
     1801 acttgatatt gtgtgtttta ttatgggaag atttacttca ttgtctcctg aaatggagtt
     1861 ttgaagcagg atcactctat ttgaaaatat acatagaaaa actgtataat ccttaaaata
     1921 agctgaaatc tattggaaac atacggtaaa caattgaaaa ggtactatat aaagtggtac
     1981 aatggtagaa aaataagcta gtaagaatca ctcttatttt agcgaaaaat tacagaaatg
     2041 aatggttttt cttgatgaaa cagagaaaag aattgtacct ctttcttggt cggacagcct
     2101 tgtattttct tatctttcta gggctgcttt acttctttag ctatcttggt cagggtcaag
     2161 gaagctttat ctataatgaa ttttaacttg aaggagaatc cctattgtgt caaataaacc
     2221 aatagcagat atgattgaaa ccattgagca ttttgctcag acacagccta gctatcctgt
     2281 ctataatgtt ttggggcagg aacacactta tggcgattta aaggctgatt cggatagttt
     2341 ggctgcagtc attgaccaac taggcttgcc tgagaagtct cctgtggttg tttttggtgg
     2401 ccaagaatat gaaatgttgg caacctttgt agcgctgact aagtcaggtc atgcctacat
     2461 tccaattgat agccattcgg ccttggagcg agtttcagct attttagaag tagcagagcc
     2521 aagcttgatt attgccattt cagcctttcc cttggagcag gtttctacac caatgataaa
     2581 tctagctcag gttcaagaag cctttgttca agggaataac tatgaaatca cgcatccagt
     2641 caagggagat gataattact acattatctt tacttctggt acgactggta agcctaaggg
     2701 agtgcagatt tcacatgata atctcctcag ctttacaaac tggatgatta tggataagga
     2761 atttgcgaca ccgagtcgtc cgcaaatgct ggcacagcca ccttattctt ttgacttgtc
     2821 tgtcatgtat tgggcaccga ccttggcact tggtggtacg cttttcactc ttccttcagt
     2881 catcactcag gactttaagc aactctttgc ggctatcttt tcattgccaa tcgctatctg
     2941 gacatcaaca ccatcctttg cagatatggc catgttgtct gaatacttca acagtgagaa
     3001 aatgcctgga gtcacgcatt tctactttga tggtgaagaa ttgacggtca aaacagctca
     3061 aaaactgcgc aagcgtttcc caaatgcccg tatcatcaat gcttacggcc caacagaagc
     3121 gacagtagct ctgtcagcag ttgccgtgac agacgagatg ttagcgactc tcaaacgcct
     3181 accaatcggc tataccaagg ctgattctcc aacctttatc attgacgagg aaggaaataa
     3241 actgccaaat ggcgaacagg gagaaatcat tgtttctggg ccagctgttt caaaaggtta
     3301 tatgaacaat cctgaaaaaa cagcagaagc cttctttgag tttgaaggtc tgccagccta
     3361 tcacacaggc gatgtgggaa ccatgacaga tgagggcttg cttctctacg gcggacgcat
     3421 ggacttccag attaagttta acggttaccg cattgagtta gaagatgtct ctcaaaacct
     3481 caacaagtct cgctttatcg aatctgctgt cgcagtaccg cgctataaca aggaccacaa
     3541 ggtacaaaat ctattggctt atgtcatctt aaaagacggt gttcgtgagc agtttgagcg
     3601 agatatcgat attaccaagg ccatcaagga agacctgaca gacatcatga tgtcctatat
     3661 gatgccatct aaattccttt accgagacag tttgccactg actccaaatg gaaagattga
     3721 catcaaagga ttgattaacg aggtgaataa gagatgatgg agttttttca acagcttcct
     3781 catttagagc catatggcaa tcctcagtat tttgtttatg tgattgctgc aaccttgccc
     3841 atctttatag gtctcttttt caagaaacgc tttgcctggt atgaagtgtt ggtaagtctc
     3901 ttctttattg tcaccatgtt ggtgggtgga aagaccaatc aactagctgc cttgggtatt
     3961 tacctttgct gggaaatatt gctcctgctt ttctacaagc attatcgaaa aagcaaggat
     4021 ggcaagtggg tcttctactt agttagtttt ctgtccctac ttccgattat ctttgtcaag
     4081 gtgcaaccag ctatcaatgg aacgcagtct ttgcttgggt tcttgggaat ttcttatctt
     4141 acctttcgtt cggttgggat tatcatcgag ctgagagatg gagtgattaa ggattttacc
     4201 ctctgggaat tcctccgttt ccttctcttc atgccaactt tctcgagtgg tccaatcgat
     4261 cgctttaagc gatttaatga aaattatcag gctattcctg agcgagatga gttgatggat
     4321 atgctggatg aatctgtccg ctatatcatg tggggctttt tgtataagtt tatcctagct
     4381 catgttttag gagagacctt actacctcct ctgaagaatt tagccttgca gtcaggtggc
     4441 ttctttaatc tctatgcctt ggcagttatg tatacttttg gtctggagct cttctttgac
     4501 tttgcaggtt attctatgtt tgctttggcc atctcaaact tgatgggaat ccgtagccct
     4561 atcaacttta acaagccctt tttatcaagg gatttaaagg agttttggaa tcgctggcat
     4621 atgagtctgt ccttctggtt ccgtgacttt gtctttatgc gaatggtgat ggtgttaacc
     4681 agaaagaaag tctttaaaaa tcgtaatgta acctcaagca tggcctacat tgtaaatatg
     4741 ctgattatgg gattttggca tggtgtgacc tggtactata tcgcctatgg actctttcat
     4801 ggactaggct tggtcatcaa tgatgcctgg gttcgcaaga aaaaaacact caataaggaa
     4861 cggaaaaaag cagggaaggc tgccctacct gagaatcgct ggattcagtt gcttggcatg
     4921 gttgtcactt tccatgttgt catgttgtca ttcttaatct tttctggatt cttgaataat
     4981 ctatggttta aaaaataaaa ggaaataaaa tatggatatc aaatcagaag ttatcgaaat
     5041 tattgatgag ttgtttatgg aagatgtttc tgacatgatg gatgaagatc tttttgatgc
     5101 aggtgtcttg gatagtatgg gaacggttga gttgattgtg gagattgaga accgttttga
     5161 cattcgtgtc cctgtaacag agtttggtcg tgacgactgg aatacagcta ataaaatcat
     5221 agctggtatt gtggagctac aaaatgctta aacgcttatg gatgatcttc ggaccggtct
     5281 tgatcgctgg tttgttggtt tttctgctca ttttctttta tcctactgag atgcatcata
     5341 atctaggagc tgaaaagcgt tcagcagtgg ctactactat cgatagtttt aaggagcgaa
     5401 gtcaaaaagt cagagcacta tctgatccaa atgtgcgttt tgttcccttc tttggctcta
     5461 gtgaatggct tcgttttgac ggtgctcatc ctgcggtatt agctgagaaa tacaatcgtt
     5521 cctaccgtcc ttatctttta ggacaggggg gagctgcatc gcttaaccaa tattttggaa
     5581 tgcaacagat gttaccacag ctggagaata aacaagttgt gtatgttatc tcacctcagt
     5641 ggttcagtaa aaatggctat gatccagcag ccttccagca gtattttaat ggagaccagt
     5701 tgactagttt tctgaaacat caatctgggg atcaggctag tcaatatgca gcgactcgct
     5761 tactgcaaca gttcccaaac gtagctatga aggacctggt tcagaagttg gcaagtaaag
     5821 aagaattgtc gacagcagac aatgaaatga ttgaattatt ggctcgtttt aatgaacgcc
     5881 aagcttcctt ttttggtcag ttttcggtta gaggctatgt taactacgat aagcatgtag
     5941 ctaagtattt aaaaatcttg ccagaccagt tttcttatca ggcaatagaa gatgttgtca
     6001 aagcagatgc tgaaaaaaat acttccaata atgagatggg aatggaaaat tatttctata
     6061 atgagcagat caagaaggat ttgaagaaat taaaggattc tcagaaaagc tttacctatc
     6121 tcaagtcgcc agagtataat gacttgcagt tggttttaac acagttttct aaatctaagg
     6181 taaacccgat ttttatcatt ccacctgtta ataaaaaatg gatggactat gctggtctac
     6241 gagaggatat gtaccaacaa acggtgcaga agattcgcta ccagttagaa agtcaaggtt
     6301 ttaccaatat agcagatttt tctaaggacg gcggggagcc tttctttatg aaggacacca
     6361 ttcaccttgg ttggttgggt tggttggctt ttgacaaggc agttgatcct ttcctatcca
     6421 atcccacacc agctccgact taccatctga atgagcgctt tttcagcaaa gattgggcga
     6481 cttatgatgg agatgtcaaa gaatttcaat agataatata atatagaaga gttcaagaat
     6541 gaaactagtt ttcacgtttt ttcttgactc tttttttgct tgtgatataa ttaactggta
     6601 aacaaaatgt caaagaatag tatttttctc ttaaaaaaga gaagtctaaa aggaaaggag
     6661 tcagatatga gacagctagc aaaggatatc aatgcttttt tgaatgaggt gattttgcag
     6721 gcggaaaatc agcatgaaat cctaataggt cattgcacta gcgaggtggc cctgaccaat
     6781 actcaggagc atatccttat gctcttgtca gaggaatctt taacaaattc agaattggcc
     6841 cgtcgtctca atgtcagtca ggcggcagtt accaaggcca ttaagtcttt ggtcaaggaa
     6901 gggatgttgg aaacatctaa agattctaaa gatgcgcgtg tgatttttta tcagttgact
     6961 gacttggctc gtccaatcgc tgaggagcac caccatcacc atgagcatac acttttaacc
     7021 tatgaacaag tggcgactca gtttactcca aatgaacaaa aagtgattca gcggtttttg
     7081 actgctttag taggagaaat caaataatga gatatattac ggtagaggat ttgtccttct
     7141 attatgataa ggaacctgtt cttgaacata tcaattattg tgttgatagt ggggaatttg
     7201 ttaccttgac tggggaaaat ggagcggcta agacgacgct catcaaggcc agtcttggaa
     7261 ttctgcaacc acgcattgga aaggtggcta tttcaaagac aaatacgcaa ggtaagaaat
     7321 tgagaatagc ctatcttcct caacaaattg ccagttttaa tgctggtttt ccaagtacgg
     7381 tctatgaatt tgtcaagtcg ggtcgctatc cgagaaaagg ctggttccgt cgtttgaata
     7441 ctcatgatga ggagcatatc aaggctagtc tggactcagt tggcatgtgg gaacatcgag
     7501 acaaacgctt ggggtctcta tctgggggac aaaagcagcg agcggtaatt gcgcgtatgt
     7561 ttgcttctga ccctgatgtg tttatcctag acgagccgac aacggggatg gatgcaggaa
     7621 gtaaaaatga attttacgaa ctcatgcacc acagcgccca tcatcatggc aaggctgttt
     7681 tgatgattac ccatgaccct gaagaagtta aggattatgc ggatcgcaat attcatctag
     7741 tccgtaacca agactcgcca tggcgttgtt tcaacgttca tgagaatggg caggaggtgg
     7801 gccatgctta gtttattatc ttacgacttt atacaacgcg cctttttggc ggttattgct
     7861 atgagtcttt tctcaccggt attgggaacc ttcctcatct tgcgtcgtca gagtttgatg
     7921 agtgataccc ttagccacgt ctcactttca ggtgtagcct ttggtctggt tttggggatt
     7981 tctccaactg tttctactat tgccattgtc ttgattgcgg cggtctttct ggagtatctc
     8041 cgtacggttt acaagagctt tatggaaatc gggacagcta tcctcatgtc aacaggtttg
     8101 gctgtttctc tgattgtcat gagcaagggt agaagctcga gttcaatgag tttggaccaa
     8161 tatctctttg gttcgatcgt gactatcagt gaagaacagg tcatttccct ctttgtcatt
     8221 gcggcggttg ttttgatttt gacctttctc tttcttcgtc ctatgtatat cttaactttt
     8281 gacgaagata cggcctttgt ggatggcttg ccagttcgta ccatgtccat tctttttaac
     8341 atggtgacag gggtggctat tgcccttatg attcctgcag caggagctct tctggtatcg
     8401 accattatgg tcttgccagc tagtattgcc ctgcgtctgg ggaaaaactt taaatcggtt
     8461 atgctgcttg ccagtgcgat tggctttttg ggaatggtag caggacttta catttcctac
     8521 tatgcagaaa cacctgcaag tgcaagtatt accattattt ttgtaactgt ctttatacta
     8581 atcagtttag taagacgttt tatcaaatag gagacgaacg tgaaaaaaat tagcttatta
     8641 ctagccagtc tatgtgcctt gtttttagtg gcttgttcca atcaaaaaca ggcagatggt
     8701 aaactcaata tcgtgacaac cttttaccct gtctatgaat ttaccaagca agtcgcagga
     8761 gatacggcta atgtagaact cctaatcggt gctgggacag aacctcatga atacgaacca
     8821 tctgccaagg cagttgccaa aatccaagat gcagatacct tcgtttatga aaatgaaaac
     8881 atggaaacat gggtacctaa attgctagat accttggata agaaaaaagt gaaaaccatc
     8941 aaggcgacag gcgatatgtt gctcttgcca ggtggcgagg aagaagaggg agaccatgac
     9001 catggagaag aaggtcatca ccatgagttt gacccccatg tttggttatc accagttcgt
     9061 gccattaaac tagtagagca catccgcgac agcttgtcag cagattatcc tgataaaaaa
     9121 gtgacctttg agaagaatgc agctgcctat atcgaaaaat tgcaagcctt ggataaggct
     9181 tacgcagaag gcttgtctca agcaaaacaa aagagctttg tgactcaaca cgcagccttt
     9241 aactatcttg ccttggacta tggactcaaa caagtcgcaa tctcaggact ttctccagat
     9301 gcagagccat cagctgctcg cttggcagaa ttgacagagt atgtcaagaa aaataaaatc
     9361 gcctatatct attttgaaga aaatgcctca caagcccttg ctaacacact ttcaaaagaa
     9421 gcaggtgtca aaactgatgt cctcaatcct ttagaaagtc tgacagaaga ggacaccaag
     9481 gctggagaaa actacatttc cgtgatggag aaaaacctca aggctttgaa acaaacaaca
     9541 gaccaagaag gcccagcaat cgaacctgaa aaggcagagg ataccaagac agtccaaaat
     9601 ggttacttcg aggatgcagc tgtcaaggac cgcaccttga gtgactatgc aggtaactgg
     9661 caatcagttt atcctttcct tgaagacggc acgtttgacc aagtctttga ctacaaggct
     9721 aagttgactg gtaagatgac ccaggctgag tacaaggctt actatacaaa aggctatcag
     9781 acagatgtga ctaagattaa cattactgat aatactatgg aatttgttca aggtggacaa
     9841 agcaagaaat acacttacaa gtatgtcggt aagaaaattt tgacttacaa gaaaggcaat
     9901 cgtggcgtgc gtttcctctt tgaagccaca gatgctgacg ctggacaatt caagtatgtt
     9961 cagtttagtg atcacaatgt tgccccagtt aaggcagaac atttccatat cttctttgga
    10021 ggcacaagcc aagaagccct ctttgaagaa atggacaact ggccaaccta ctacccagat
    10081 aacctatctg gccaagaaat cgcccaagaa atgttggcgc attgatgaga aatcgactag
    10141 ttcataagag ctagtcggtt ttttgatact agatggctaa cttcattata gacctttcag
    10201 aactttaaac aataaataaa actcttgaaa tatctgggct tatatgctag aatgtagtta
    10261 gtgtataagg ttcattagaa caccaaagcc cctaactagt gccatagtta agggcttttt
    10321 tgacgtatct tagcgattta acgggtgttt ataggctagt cagtcggtct acttcttacc
    10381 atctagccat ttgcagacga aatacaagat aattccagct ataacatctg ctataatagt
    10441 aagagcaagc tctggtataa ggctcattag tttcacctcc tctcacgaac ccataggaac
    10501 gtaatcggta accgatgaca aaaatagtat accacactaa atttagatca tcaacctcac
    10561 ttaatgcttg aactattgta gattatatgc taaaatgtag ttaattgata aggttcatta
    10621 gaacaccaaa gcccctaact atggccgtag ttaagggctt ttttgacgta tcttagcgat
    10681 ttaacgggtg tttataggct agtcactcgg tctactcctt actatctagc catctgcaga
    10741 cgaaatacaa gataattcca gctataacat ccgctataat agtaagagcg agctctatga
    10801 taaggctcat tagtttcacc tcctctcacg aacccatagg aacgtaatcg gtaaccgatg
    10861 acaaaaatag tataccacaa tatatttaga tcatcaaggt cacttaattc ttgaaatata
    10921 gggtctaggc gacaaagtct ttaaaatcag aaaaacgcat aatatcaggt gtgcaaaaac
    10981 ttgatactat gcgttttatt gtgggaaggt ttactccatt ttctcctgaa attgagtttt
    11041 tgtccagcct ctgtttttag aattgctaag aaaataatgt catgtggtga atatttgtaa
    11101 atcagtcagc agacagaacg aatactcttc gaaaatctct tcacatcatg tcagcttcgt
    11161 cttgccgtgt ccatggggga cttgacttga tcagttttca aatctgtact ttgagcaagc
    11221 tgagactagc ttcctatttg attttcattg aatatcagaa acccattctc catcaaataa
    11281 ttcgactgcg tctaataatt tttggtctgg caaggtgtca gaaataaagg ttgtgtattt
    11341 ggagagggga ttaattttaa aaaatccagt cttgtaaaat ttagaactat caatcagtaa
    11401 gatggtttca tgggctttgt caataatatt cttttttgaa atagcttggc tgagagaagc
    11461 ttcataaaca tattggtcat caatacctct tgctgaacaa aatgctaaat cgatattaaa
    11521 atgatctaat aaagaatttt ccttatcata gttgaccacg gaacaggatt gatgtttgac
    11581 ctcgccagat gtgataaaga ttttggagct atctttaaca gtttcagata gggtttgtgc
    11641 agtatgtaaa ccatttgtaa aaataatcaa attatcaagt tcagaaagat agggacaaag
    11701 ttcgtagaca gtagtactag aatctagata gatacacata ccagaccgaa taaagtcttt
    11761 agcgagacta gcgattagtc ttttttgcct agtactttct ccttcccgta tttgatgaga
    11821 aagttcaatt gtgttcatag aggacagggt cacgtatccg tgctttcttt tgataagacc
    11881 ttgattttct aagaaaatta aatcacgacg taaggtactt gtgctggaga aagtgatttc
    11941 tgccagctct tttacggcaa ttcttttttt ctttttaata atttcaatca attcaagtac
    12001 acgttcatct tttatcataa gctcctccta atttatcatt tcaactatat tatagcacaa
    12061 attggaggaa tttgaattat ttttatgaat attgggttaa catttgaaca ttattcaagt
    12121 aagcgttcac atattgaaaa aataaaacgt ggggattata ataaagttaa tcaaggacga
    12181 agagagaaga aaaatggaag cggttttagc aatagattta ggtgcgactt ctggaagagc
    12241 aatcgttggt tacctttctg aaaataaact agtaatggaa gaaataaatc gcttttctaa
    12301 tctacctatt agagtaaaag ggcatttatc ttgggatatt gactttctac tagctaaaat
    12361 tcttgaaagt atccgcttgg ctaatactag ttacaagatt ttatctatcg gtattgacac
    12421 atggggagtt gattttggac tgattgataa tgaaggtaag ctgttatcac aacctgttca
    12481 ttatcgtgat gaaagaacaa agggagtgtt aaaggaaata tctgaaatga ctgaattaga
    12541 aaaactgtat tcagagacag gaaatcagat tatggagata aataccttgt ttcaactctt
    12601 taaggcacgt caagaatctc ctgactcttt ctataagacc aataagattc ttttaatgcc
    12661 agatttgttt aattatctct tgacaggtaa gtttgctaca gaaaaaagca ttgcttcaac
    12721 aactcaatta tttgatccta ggagtcaaaa ttggaatcag aatatcttaa aactatttga
    12781 attggattca tctttacttc ctgaaattgt ttcagaggga aatgttcttg gaaggataaa
    12841 aaaggagtat ggtttaggcg atattcctgt tgtgaatgtt tgtagtcatg atacagcaag
    12901 tgcgattgtc tcagtaccta agacagaagg tagtttattt atttcatcag gtacttggtc
    12961 tttggttgga gtggaactta cttcaccgat tcttactacc gaatccttca gttatggatt
    13021 tacaaatgaa gtcggtaaag atggagtgat tacatttctg aagaattgta cagggttgtg
    13081 gatcatagag gaactaagac gttcatttga acgaagaggg aaagcctatt cttttgatga
    13141 tattaggaca atggtggaga aagaaaaaga aaatcttcct ctgattgata ctgaatcaac
    13201 tgaatttgca acagaatctg atatgcacaa gactttgaca gaatatctag cttatcatca
    13261 tgaaactaga gagtggacag atggacaact atttaagatt gtttatgaaa gcctagctga
    13321 aacgtatagg aaagcgatag agttattaga agaactaact cataaggttt ataagaggat
    13381 atatgtgatt ggaggaggtg ctagagccag ttattttaac caaatgattg ctgatagaac
    13441 tggtaaagag gttcttacag gtttgactga ggctacagct gtggggaata ttgttgtgca
    13501 gctcatagct atgggacaat taaaagggat ggaagaggct caccatgtta ttgaggagtt
    13561 tctacaatta gagagttatt actcccaaaa gaattaaaaa gattgagagt ttgtaaattt
    13621 gcctccctcc cccttcttag cttttgtgca ggaagggggg ataattggtg aattgaaaaa
    13681 tatttagtgt tttgatatga ggaggacaag gatgtcagat gtaaaacaag aattaattaa
    13741 atatggtaag aagctagtag aaacagattt gacgaaagga acaggtggga atctcagcgt
    13801 tttcgatcgt gaaaaacaat tgatggcaat taccccgtcg ggtattgatt tctttgaaat
    13861 caaagaatcc gatattgtag tgatggatat taatggaaat gttgtagagg gagaacgctt
    13921 gccatctagc gaatggtata tgcatttgat tcaatatcaa actcgtgatg atatcgatgc
    13981 aattatccat gctcatacaa cttatgcaac agtattagct tgtctcagag aaccacttcc
    14041 agcgagtcat tatatgattg cagtggcagg gaaagatgtt cgggtagctg agtatgcaac
    14101 atatggcacg aaagaattgg ctgtgaatgc agctaaagca atggaaggtc gtagagcagt
    14161 tttactagcg aatcatggaa ttttagcagg tgcacaaaat ttattgaatg catttaatat
    14221 tgttgaagaa gttgaatatt gtgcaaaaat ttattgttta gctaagaatt ttggagagcc
    14281 agtagttctt cctgatgagg agatggaatt gatggcagaa aaatttaaaa catacggtca
    14341 gagaaaatag ggaggatatt aatgttaaaa catataccga aaaatatttc tccagattta
    14401 ttgaagactt taatggaaat gggacatgga gatgaaatag tattagctga cgcgaattat
    14461 ccttctgcct catgtgcaaa taagctaatt cgttgtgatg gcgtaaatat tccagaatta
    14521 ttagattcca ttctgtattt aatgccatta gatagttacg tcgatagttc aattcagttt
    14581 atgaacgttg tttcgggtga tgatattcct aagatatggg gtacctatag acagatgatt
    14641 gaaggtcatg gtacagatct taaaacgatt acttatctta gaagagaaga cttttatgaa
    14701 cgtagtaaga aagcttatgc tattgttgct acaggagaaa cttcacttta tgctaatatt
    14761 atccttaaga aaggagtagt tgttgaaaga gaaaatgttt aatagaggaa ttttagttgc
    14821 cagtcatggt gattttgcta gcggagctct catgaccgca gaaatgtttg ttggtgagac
    14881 aacaaatgat agagttagga cattaggttt gatgcctgga gagaatattg tagagtttga
    14941 gcattatttt aaaaatcaag tggatgaact gttagactca aatcaagagg ttatcgtttt
    15001 gactgacttg attggaggaa gtcctaataa tgtggctttg tcacggtttt taaatttgga
    15061 ttcagttgat attgtaacag ggtttaatat tcctctccta gtggaattaa tatcaaatta
    15121 tgattcaaaa atcaatttag aagaaattgt tcacaatgct caaaatagtt tgtttaatgt
    15181 taaacaacaa cttaacgtag aggaggaaga aaatttatgt ctatagagtt tgttcgtatt
    15241 gatgaccgtc tggtacatgg tcaagttgtc actacgtggc taaaaaagta tgatattgag
    15301 caagttatca ttgttaatga tcgcatctca gaagataaaa cacgacaatc tattttaaag
    15361 atttctgcac cagtaggttt aaaaattgtt ttctttagtg taaaacggtt tgtggaagtt
    15421 ttaaactctg tgccaataaa aaagagaaca atgctgatat atacaaatcc aaaagatgtg
    15481 tatgattcta ttgaaggaaa tttaaaattg gagtacctca atgtaggaca gatgagtaaa
    15541 acggaggaaa atgaaaaggt aacgggaggt gtagctctag gtgaagaaga caaatattat
    15601 tttaagaaaa tagttgataa gggaacgaga gttgaaattc aaatggttcc taatgataaa
    15661 gttacaatgt tggaaaaatt tttataaaaa taatttaagg aggtacagta tatgctattc
    15721 acacaagcat tactggtgac attagttggg attattgcca ctattgacta taatggaccg
    15781 ttatttatga ttcaccgtcc gttagttaca agtgcaatgg ttggcttagt cttaggagat
    15841 ttcacccaag gtgttcttat tggttcagct cttgaattaa cttggctcgg tgtaacaggt
    15901 attggaggtt acactccacc agatactatt tcaggtgcga ttattggtac tgcatttggt
    15961 attttatctg gtcaaggaga aactgctggt atcgctatag cagttccaat tgcagttgct
    16021 acccaacagt tggatgttct tgcaaaaact ttagatgttt attttgtgaa aaaagctgat
    16081 aatgatgcta aaaacggaga ttattcaaag atcggttttt atcattattc aagtttggtt
    16141 ttaatcacgt tatttaaaat tgtaccaatt ttcctagcta ttatgcttgg aggggaatat
    16201 gtggcagact tgtttgctaa ggttccacca atcgttatgc agggacttaa ctctgcaggt
    16261 gctttactac cttcaattgg ttttggtatg cttttaaata tgatgctcaa gaaaaatatg
    16321 tgggtattct tgttgattgg attcatttgt tctgtgtatg gaggaatgtc aaccattggg
    16381 atctcactag ttggtattgc ggtagcatac ttctacgata tgattggaag taaaccacaa
    16441 gaaacaactt caagtagtga tgttgaggag gatcttgatc tatgatgaat aataaagtaa
    16501 ctaaagttga acttaaaaaa gttttcaaac gaagttttat gtatggttct tcatggaact
    16561 atgagagaat gcagaaccta ggttttctat atacaattct tccagtattg aaaaaactat
    16621 acccagacaa agattcagct tctcctgcaa tgaaacgtca ccttgagttt ttcaatactc
    16681 atcaaacagc ggcaccattt attcttggag ttacttccgc tatggaagaa caagaaggaa
    16741 atgaaggtgc agcttcaatt actggtatta aagttggctt gatggggcca ctggctggtc
    16801 taggagatag tttgttctgg ctgacactag ttcctatctg ttttagtatt ggtgcgtctt
    16861 attctaaaga cggcggtgct ttaggtatct ttatcgcctt aatattgttt aatattatta
    16921 atattcctgt taaatatttc ggtttgaaat atgggtatac taagggttct agtcttatcc
    16981 aagaaaataa tacaaaagga acattgaatc gcgttacgag tatggcgaca gcattagggc
    17041 tagtactagt gggtggtttg attccatcaa tggttggtat taattttgga ttagaattta
    17101 agcaggggga acttgttatt tctgttcaag aaatgattac aaaattaatt ccaggattta
    17161 tccctatggc tttgacttta ttaatgtgta aattaattag aaaaggaaag aatccggttg
    17221 tactaatctt tagtgttatg gctattggag ttatcctagt tgttttagga attttgaagt
    17281 agtagaaagt gtggaggtgg tatttgggat atcacctcca ttttggaaga gaggtaaaga
    17341 gtgaaattat ggtataagaa agctgcctca aattggaatg aagccttgcc gattgggaac
    17401 ggtcatttag gtggtatgat ttatggttca gctacaaaag aatgtattca actaaacgat
    17461 gagactattt ggtatagagg aaagtcagat agaaataatc cagactcact attgcatctt
    17521 aaaaaaattc gggaatatct tttagatgga gaaattcaga aagccgaaga attgataaag
    17581 ttaacaatgt ttgctacccc aagagatcaa agccactatg aattacttgg ggaactttac
    17641 attgagcata tagatattca gtcttgtgct ctttcattgt atgaaagaga gctagattta
    17701 gatacagcta tttctaatgt tgtgtttgag cctaatagtt gtaatttaca aataaaaaga
    17761 gaatatttta cgagttttaa taagaatatt ttatgttgcc gtatagtgtc atcagttcaa
    17821 aacacattaa atttaaacat taatttgggt agaaataaac ggtttaatga cgaagtatct
    17881 aaactggatt caagtacaat tttaatgtcg gcctctgctg gaggtagaaa aggtgttcag
    17941 tttaaagtag tatgtcattc taaagttacg gatggtgaag taagtgtatt gggagagaca
    18001 atagttattc ggaatgctac agaggtattt ctttatctca aatcaatgac ggattattgg
    18061 ggaaatatag atatttcttc tcttcaggga gaatttagta gtattgatta ctttacagaa
    18121 aaagatgaac atgtaaaaaa atatcaggag caatttaata gagttgattt taaactagac
    18181 tatagtaaag attgtcttag cattccaacg aatctacttc ttgaaaacac taaaaagtat
    18241 agtaactact tgactaactt gttatttcat tatggaagat atctgttaat atcgtctagt
    18301 caaccgaatg gtttacctgt caatcttcaa ggaatatggt gtgatgaatt aaatccaatt
    18361 tggggttcta aatatacgat taatattaat actcaaatga attattggat ggtaggtcca
    18421 tgtgatttac cagaagtaga atatccatta tttgatatgc tcgaaagaat gagagaaccg
    18481 ggaagactaa ccgctaagaa aatgtatgga gctagaggtt ttacagcaca tcataatacg
    18541 gatggttttg gcgatacggc tccccaatct catgccatgg gggctgcaat ttgggtatta
    18601 actattccat ggttatgtac tcatatttgg gaacactatt tatatttcca agatgagcgt
    18661 attcttacgg aacattttga aatgataaaa gaagcatttc ttttctttga agattattta
    18721 tttgaggtgg atggctactt gatgacaggt ccaagtgtct caccggaaaa taaatatcgc
    18781 ttaaaaaatg gtattgaagg aaatgcttgt ctatcatcta caattgataa tcaaattcta
    18841 agatattttt gtgattcatg cattggcatt gcaaaacaat taggagacaa ttcggatttt
    18901 attagtcgtg tgaaggagtt aaaaaagaaa ctacctaaaa caaaaatagg tagtaatggg
    18961 caaatccaag aatggttaga agattatgaa gaagtagagc ctgggcatag acacatttca
    19021 cctctatttg ggctttatcc ttataatgag attgatattc ataaaactcc ggaattagca
    19081 gaagcagcta aaatcactat caataggaga ttatcaaacg ctaacttttt atcttcacag
    19141 gagagggagc aagcgattaa taattggtta gtaagtggtt tgcatgctag tacacaaaca
    19201 ggttggagtg ctgcatggct gattcatttt tttgcgagac tatatcaagg tgaacctgct
    19261 tataaccaga ttaatggttt gttaaataat gcgactcttg gcaatttatt tcttgaccat
    19321 ccaccatttc aaattgatgg taatttaggt ttggtgagtg gaatttgtga attattagta
    19381 cagagccatc ataattggtt atcactaatt ccagctttac cttctgcttg gtcagaagga
    19441 gaagtgaaag gtttcagagt aagaggagga tataaggtat cgtttgcttg gaaaaatggg
    19501 gatataacat tcctaaaatt ggaaggagga aacaaagatc aaaaagtaag agtaagaata
    19561 tatggcaaaa atactgatgt acaaaatatt gaattggtat ttaattcaga aaaaattatt
    19621 gagttaaatt tttaggtata agtcatgaat aaagaaaaaa taaaaagaaa attaatcaca
    19681 atactgtttg tatgtattgg gatgttatgt tttggattgt tagcaggagt taaggctgat
    19741 aatcgtgttc aaatgagaac gacgattaat aatgaatcgc cattgttgct ttctccgttg
    19801 tatggcaatg ataatggtaa cggattatgg tgggggaaca cattgaaggg agcatgggaa
    19861 gctattcctg aagatgtaaa accatatgca gcgattgaac ttcatcctgc aaaagtctgt
    19921 aaaccaacaa gttgtattcc acgagatacg aaagaattga gagaatggta tgtcaagatg
    19981 ttggaggaag ctcaaagtct aaacattcca gttttcttgg ttattatgtc ggctggagag
    20041 cgtaatacag ttcctccaga gtggttagat gaacaattcc aaaagtatag tgtgttaaaa
    20101 ggtgttttaa atattgagaa ttattggatt tacaataacc agttagctcc gcatagtgct
    20161 aaatatttgg aagtttgtgc caaatatgga gcgcatttta tctggcatga tcatgaaaaa
    20221 tggttctggg aaactattat gaatgatccg acattctttg aagcgagtca aaaatatcat
    20281 aaaaatttgg tgttggcaac taaaaatacg ccaataagag atgatgcggg tacagattct
    20341 atcgttagtg gattttggtt gagtggctta tgtgataact ggggctcatc aacagataca
    20401 tggaaatggt gggaaaaaca ttatacaaac acatttgaaa ctggaagagc tagggatatg
    20461 agatcctatg catcggaacc agaatcaatg attgctatgg aaatgatgaa tgtatatact
    20521 gggggaggca cagtttataa ttttgaatgt gccgcgtata catttatgac aaatgatgta
    20581 ccaactccag catttactaa aggtattatt cctttcttta gacatgctat acaaaatcca
    20641 gctccaagta aggaagaagt tgtaaataga acaaaagctg tattttggaa tggagaaggt
    20701 aggattagtt cattaaacgg attttatcaa ggactttatt cgaatgatga aacaatgcct
    20761 ttatataata atgggagata tcatattctt cctgtaatac atgagaaaat tgataaggaa
    20821 aagatttcat ctatattccc taatgcaaaa attttgacta aaaatagtga ggaattgtct
    20881 agtaaagtca actatttaaa ctcgctttat ccaaaacttt atgaaggaga tgggtatgct
    20941 cagcgtgtag gtaattcctg gtatatttat aatagtaatg ctaatatcaa taaaaatcag
    21001 caagtaatgt tgcctatgta tactaataat acaaagtcgt tatcgttaga tttgacgcca
    21061 catacttacg ctgttgttaa agaaaatcca aataatttac at
//
LOCUS       DAVBDR010000037        20838 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.037, whole genome shotgun sequence.
ACCESSION   DAVBDR010000037 DAVBDR010000000
VERSION     DAVBDR010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20838)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20838)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20838
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.037"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            182..658
                     /locus_tag="VQ540_001368"
     CDS             182..658
                     /locus_tag="VQ540_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2545165.1"
                     /translation="MKLSLYSEVEHYHFLSSYSLNDITYTDTPKNIIEKSKKDKYRYP
                     IVILNKDHKVIGFFCLHLNTGPKEYGYYQNDYALIRGFSIHDNFRNQGYGSNALNEIF
                     EFIDSTLKLEINHIILAVNEKNILAQKAYRNSGFSVVKKDLEGKRGKLIIMEKSRN"
     gene            complement(1332..1724)
                     /locus_tag="VQ540_001369"
     CDS             complement(1332..1724)
                     /locus_tag="VQ540_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HET2545166.1"
                     /translation="MWKKKKVKAGVLLYAVTIAAIFSLLLQFYLTRQIAHYQDYALNK
                     EKLVAFAMAKRTKDKAEQESGEQVFNLGQVSYQNKKTSLVTTVRTDKSQYEFLFPSVK
                     IKEEKTDKKEEVATDSSEKAEKKIRREA"
     gene            complement(1702..2163)
                     /locus_tag="VQ540_001370"
     CDS             complement(1702..2163)
                     /locus_tag="VQ540_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000250539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HET2545167.1"
                     /translation="MVQNSCWQSKSHKVKAFTLLESLLALIVISGGLLLFQAMSQLLI
                     SEVRYQQQSEQKEWLLFVGQLEAELDRSQFEKVEGNRLYMKQDDKDIAIGKSKSDDFR
                     KTDASGRGYQPMVYGLKSAQITEDNQLVHFRFQFQKGLEREFIYRVEKEES"
     gene            complement(2126..2386)
                     /locus_tag="VQ540_001371"
     CDS             complement(2126..2386)
                     /locus_tag="VQ540_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000601743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2545168.1"
                     /translation="MILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVA
                     KMALQTGQNQVSINGVEIQVFSSEKGLEVYHGSEQLLAIKEP"
     gene            complement(2391..2819)
                     /locus_tag="VQ540_001372"
     CDS             complement(2391..2819)
                     /locus_tag="VQ540_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012386909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HET2545169.1"
                     /translation="MEGQIVKSMIKAFTMLESLLVLGLVSILALGLSGSVQSTFAAVE
                     EQIFFMEFEELYRETQKRSVASQQKTSLNLDGQMISNGSQKLTVPKGIQAPSGQSITF
                     DRAGGNSSLAKVEFQTSKGAIRYQLYLGNGKIKRIKETKN"
     gene            complement(2788..3114)
                     /locus_tag="VQ540_001373"
     CDS             complement(2788..3114)
                     /locus_tag="VQ540_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HET2545170.1"
                     /translation="MKKMMTFLKKAKVKAFTLVEMLVVLLIISVLFLLFVPNLTKQKE
                     AVNDKGKAAVVKVVESQAELYSLDKNEDATLSKLQGDGRITEEQVKAYNEYYTKNGGA
                     NRKVND"
     gene            complement(3116..4132)
                     /locus_tag="VQ540_001374"
     CDS             complement(3116..4132)
                     /locus_tag="VQ540_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000355375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HET2545171.1"
                     /translation="MDISQVFRLRRKKLATAKQKNIITLFNNLFSSGFHLVETISFLD
                     RSSLLDKQCVTQMRTGLSQGKSFSEMMESLGCSSTIVTQLSLAEVHGNLHLSLGKIEE
                     YLDNLAKVKKKLIEVATYPLILLDFLLLIMLGLRNYLLPQLDSSNIATRIIGNLPQIF
                     LGMVGLVSVLALLALTFYKRSSKMSVFSILARLPFIGIFVQTYLTAYYAREWGNMISQ
                     GMELTQIFQMMQEQGSQLFKEIGQDLAQTLKNGREFSQTIGTYPFFRKELSLIIEYGE
                     VKSKLGSELEIYAEKTWEAFFTRVNRTMNLVQPLVFIFVALIIVLLYAAMLMPMYQNM
                     EVNF"
     gene            complement(4080..5021)
                     /locus_tag="VQ540_001375"
     CDS             complement(4080..5021)
                     /locus_tag="VQ540_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000249584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II/IV secretion system protein"
                     /protein_id="HET2545172.1"
                     /translation="MVQEIAQEIIRSARKKGTQDIYFVPKLDAYELHMRVGDERCKIG
                     SYDFEKFAAVISHFKFVAGMNVGEKRRSQLGSCDYAYDQKMASLRLSTVGDYRGHESL
                     VIRLLHDEEQDLHFWFQDIEELGKQYRQRGLYLFAGPVGSGKTTLMHELSKSLFKGQQ
                     VMSIEDPVEIKQDDMLQLQLNEAIGLTYENLIKLSLRHRPDLLIIGEIRDSETARAVV
                     RASLTGATVFSTIHAKSIRGVYERLLELGVSEEELAVVLQGVCYQRLIGGGGIVDFAN
                     RDYQEHQAAKWNEQIDQLLKDGHITSLQAETEKISYS"
     gene            complement(5097..5462)
                     /locus_tag="VQ540_001376"
     CDS             complement(5097..5462)
                     /locus_tag="VQ540_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HET2545173.1"
                     /translation="MYRVIEMYGDFEPWWFLEGWEEDIVASRKFDQYYDALKYYKTCW
                     FRLEQESPLYKSRSDLMTIFWDPEDQRWCDECDEYLQQYHSLALLQDEQVIPDEKLRS
                     GYEKQTSQERNRSCRMKLK"
     gene            complement(5613..6671)
                     /locus_tag="VQ540_001377"
     CDS             complement(5613..6671)
                     /locus_tag="VQ540_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent alcohol dehydrogenase family
                     protein"
                     /protein_id="HET2545174.1"
                     /translation="MKAYTYVKPGLASFVDVDKPVIRKPTDAIVRIVKTTICGTDLHI
                     IKGDVPTCQSGTILGHEGIGIVEEVGEGVSNFKKGDKVLISCVCACGKCYYCKKGIYA
                     HCEDEGGWIFGHLIDGMQAEYLRVPHADNTLYHTPEDLSDEALVMLSDILPTGYEIGV
                     LKGKVEPGCSVAIIGSGPVGLAALLTAQFYSPAKLIMVDLDDNRLETALSFGATHKVN
                     SSDPKKAIKEIYDLTDGRGVDVAIEAVGIPETFDFCQKIIGVDGTVANCGVHGKPVEF
                     DLDKLWIRNINVTTGLVSTNTTPQLLKALESHKIEPEKLVTHYFKLSEIEKAYEVFSK
                     AADHHAIKVIIENDISEA"
     gene            complement(6834..7985)
                     /gene="nagA"
                     /locus_tag="VQ540_001378"
     CDS             complement(6834..7985)
                     /gene="nagA"
                     /locus_tag="VQ540_001378"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HET2545175.1"
                     /translation="MPNYIKADQFFYPHGVRRGGYLELVDGKFGKHVEQIPEGAEVID
                     YTGYSIAPGLVDTHIHGYAGVDVMDNNIEGTLHTMSEGLLSTGVTSFLPTTLTATYEQ
                     LLAVTENLGNHYKEATGAKIRGIYYEGPYFTETFKGAQNPTYMRDPGVEEFHSWQKAA
                     NGLLNKIALAPERDGVEDFVRTVTGEGVTVALGHSNATFDEAKKAVDAGASVWVHAYN
                     GMRGLTHRELGMVGAMYQLPHTYAELICDGHHVDPKACEILIKQKGTENIALITDCMT
                     AGGLEDGDYMLGEFPVVVANGTARLKSTGNLAGSILKLKDGLKNVVEWGIANPHEAVM
                     MASFNPAKSVHIDDVCGQIREGYDADFIVLDKDLELVATYLDGVKRYQA"
     gene            complement(8138..9955)
                     /locus_tag="VQ540_001379"
     CDS             complement(8138..9955)
                     /locus_tag="VQ540_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HET2545176.1"
                     /translation="MRIKWFSLIRIIGLLLVLLYHFFQTIFPGGFFGVDVFFTFSGFL
                     ITALLIEEFSKNNEIDLIGFFRRRFYRIVPPVVLMVLVTMPFTFLVRQDYVAGIGGQI
                     AGVLGFMTNFYELLTGGSYESQFIPHLFVHNWSLAVEVHYYILWGLAVWFLSKQAKSN
                     GQLKGMIFLLSATAFLISFFSMFIGSFLVTSYSSVYFSSLTHVYPFFLGSMLATIVGV
                     RQTTSLVKQLDKIWDLRKTLVVFGGGFGFLVLLTFFVKFTYLFAYLIGFLLASLAALA
                     MILAARVLHEKTHHIQEPKIISFLADTSYAVYLFHWPFYIIFSQLTSNLLAVLLTLIC
                     SYGFASLSFYVLEPWIAGKNTPILQTLRPLPYIHAILAAGTGILTFIVCMVTLLAPQV
                     GAFETDLTVNGLKQAATNIGQTKVMAERADANSLGIADGTMLIGDSVALRANTALQTA
                     LPGAQINAQVSVTTKTANEIMLNNSQNKFLPKTVVIATGVNNPENYKDDWDSIVKNLP
                     KGHHMILVTPYEGDKTKETYAIVEKAAAYMRELAEKTPYITIADWNQVAKEHPEIWAG
                     TDQVHFGSESSTIEAGAKLYADTIATALQTAQDKPVKSK"
     gene            complement(10056..11198)
                     /gene="tgt"
                     /locus_tag="VQ540_001380"
     CDS             complement(10056..11198)
                     /gene="tgt"
                     /locus_tag="VQ540_001380"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HET2545177.1"
                     /translation="MSDSPIKYRLIKKEKHTGARLGEIITPHGTFPTPMFMPVGTQAT
                     VKTQSPEELKEMGSGIILSNTYHLWLRPGDELIARAGGLHKFMNWDQPILTDSGGFQV
                     YSLADSRNITEEGVTFKNHLNGSKMLLSPEKAISIQNNLGSDIMMSFDECPQFYQPYD
                     YVKKSIERTSRWAECGLKAHRRPHDQGLFGIVQGAGFEDLRRQSAHDLVSMDFSGYSI
                     GGLAVGETHEEMNAVLDFTTQLLPENKPRYLMGVGAPDSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAQFAEDFTPLDPECDCYTCNNYTRAYLRHLLKADETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFRKYFVEKYGYNKSGRNF"
     gene            11328..12185
                     /locus_tag="VQ540_001381"
     CDS             11328..12185
                     /locus_tag="VQ540_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HET2545178.1"
                     /translation="MNYPKIDLKTIRQESKHFQADTPRLFLLYILPSMLVILSGFLNP
                     LSRIHGTVLEQPFFSILGQILQTYLFPLLVSFIGTILLTSSVYATLTLMKDSKTEPSV
                     KNSLALFDEERFSQTFLTLLLKRFYLFLWSIPNLLGIYLLFYSSFLAKKFVTLHPEFP
                     NLDLSSVETERFLMVFGLYFLASLILIIVGNILYIPQYYAYSQVEFLLCYSLDLGQVP
                     PRRILKTSRSFMKGYKFQHFVLDLQLLPWYFLNWITFGIASFSLLPYIQCTKIMFYRA
                     VLARKRPKA"
     gene            complement(12213..12857)
                     /gene="pcp"
                     /locus_tag="VQ540_001382"
     CDS             complement(12213..12857)
                     /gene="pcp"
                     /locus_tag="VQ540_001382"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HET2545179.1"
                     /translation="MKVLVTGFEPFGGEKGNPTLEAIKGLPAEIHGAEVRWLEVPTVF
                     HKSAQVLEEEMNRYQPDFVLCIGQAGGRTSVTPERVAINQDDARISDNEDNQPIDRPI
                     RPDGASAYFSSLPIKAMVQAIKKEGLPASVSNTAGTFVCSHLMYQALYLVEKKFPYVK
                     AGFMHIPYMMEQVVNRPTTPTMSLVDIRRGIEAAIGAMIEHGDQELKLVGGETH"
     gene            complement(12964..13332)
                     /locus_tag="VQ540_001383"
     CDS             complement(12964..13332)
                     /locus_tag="VQ540_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 domain-containing protein"
                     /protein_id="HET2545180.1"
                     /translation="MSIITIILTTIVALEHFYIFYLESIATRSDATSRVFNMEKEELA
                     HPSVSSLFKNQGIYKALLGVFLWYGIYFSQNLEIVTIFVLFVIGAATYGSLTADKKII
                     LKQGGSAILALISILLFKYT"
     gene            complement(13343..13768)
                     /locus_tag="VQ540_001384"
     CDS             complement(13343..13768)
                     /locus_tag="VQ540_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000890080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HET2545181.1"
                     /translation="MIEIQDLLYQLRLSEQASTQLFEKRLGISLTRYQILLFLLEHSP
                     CNQMAVQERLKIDQAALTRHFKILETEGLVERHRNPENQREVLVEAAKYAKEQLVVNP
                     PLQHIKVKEEMESILTEFERTELSRLLNKLVLGIENIEI"
     gene            complement(14193..15335)
                     /locus_tag="VQ540_001385"
     CDS             complement(14193..15335)
                     /locus_tag="VQ540_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HET2545182.1"
                     /translation="MKKRMLLASTVALSFAPVLATQAEEVLWTARSVEQIQNDLTKTD
                     NKTSYTVQYGDTLSTIAEALGVDVTVLANLNKITNMDLIFPETVLTTTVNEAEEVTEV
                     EIQTPQADSSEEVTTATADLTTNQVTVDDQTVQVADLSQPIAEAPKEVASSSEVTKTV
                     IASEEVAPSTGTSVPEEQTAETSSAVAEEAPQGTTPAEKQETQASPQAASAVEATTTS
                     SEAKEVASSNGATAAVSTYQPEETKIISTTYEAPAAPDYAGLAVAKSENAGLQPQTAA
                     FKEEIANLFGITSFSGYRPGDSGDHGKGLAIDFMVPERSELGDKIAEYAIQNMASRGI
                     SYIIWKQRFYAPFDSKYGPANTWNPMPDRGSVTENHYDHVHVSMNG"
     gene            complement(15501..16121)
                     /locus_tag="VQ540_001386"
     CDS             complement(15501..16121)
                     /locus_tag="VQ540_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001172828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HET2545183.1"
                     /translation="MQKTAFIWDLDGTLLDSYEAILSGIEETFAQFSIPYDKEKVREF
                     IFKYSVQNLLVRVAEDRNLDVEVLNQVRAQSLAEKNAQVVLMPGAREVLAWADESGIQ
                     QFIYTHKGNNTFTILKDLGVESYFTEILTSQSGFVRKPSPEAATYLLDKYQLNSDNTY
                     YIGDRTLDVEFAQNSGIQSINFLESTYEGNHRIQALADISRIFETK"
     gene            complement(16125..17405)
                     /locus_tag="VQ540_001387"
     CDS             complement(16125..17405)
                     /locus_tag="VQ540_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HET2545184.1"
                     /translation="MFKKNKDILNIALPAMGENFLQMLMGMVDSYLVAHLGLIAISGV
                     SVAGNIITIYQAIFIALGAAISSVISKSIGQKDQSKLAYHVTEALKITLLLSFLLGFL
                     SIFAGKEMIGLLGTERDVAESGGLYLSLVGGSIVLLGLMTSLGALIRATHNPRLPLYV
                     SFLSNALNILFSSLAIFVLDMGIAGVAWGTILSRLVGLVILWSQLKLPYGKLTFGLDK
                     ELLTLALPAAGERLMMRAGDVVIIALVVSFGTEAVAGNAIGEVLTQFNYMPAFGVATA
                     TVMLLARAVGEDDWKRVASLSKQTFWLSLFLMLPLSFSIYVLGVPLTHLYTTDSLAVE
                     ASVLVTLFSLLGTPMTTGTVIYTAVWQGLGNARLPFYATSIGMWCIRIGTGYLMGIVL
                     GWGLPGIWAGSLLDNGFRWLFLRYRYQRYMSLKG"
     gene            complement(17466..18950)
                     /locus_tag="VQ540_001388"
     CDS             complement(17466..18950)
                     /locus_tag="VQ540_001388"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006595200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HET2545185.1"
                     /translation="MTLVYQSTRDANNTVTASQAILQGLATDGGLFTPVTYPKVDLDF
                     DKLKDASYQEVAKLVLSAFLDDFTAEELDYCINNAYDSKFDTPAIAPLVKLDGQYNLE
                     LFHGSTIAFKDMALSILPYFMTTAAKKHGLENKIVILTATSGDTGKAAMAGFADVPGT
                     EIIVFYPKGGVSKVQELQMTTQNGDNTHVIAIDGNFDDAQTNVKHMFNDVALREKLTT
                     NKLQFSSANSMNIGRLVPQIVYYVYAYAQLVKTGEIVAGEKVNFTVPTGNFGNILAAF
                     YAKQIGLPVGKLICASNDNNVLTDFFKTRVYDKKREFKVTTSPSMDILVSSNLERLIF
                     HLLGNNAEKTAELMNALNTQGQYKLTDFDAEILDLFAAEYATEEETAAEIKRVYESDS
                     YIEDPHTAVASAVYRKYQAVTGDVTKTVIASTASPYKFPVVAVEAVTGKAGLTDFEAL
                     AQLHEISGVAVPPAVDGLEIAPIRHKTTVAAADMQAAVEAYLGL"
     gene            complement(19026..20303)
                     /locus_tag="VQ540_001389"
     CDS             complement(19026..20303)
                     /locus_tag="VQ540_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamylcysteine synthetase"
                     /protein_id="HET2545186.1"
                     /translation="MSCSIDLLKHRYLKNIKENPELFVGIELEYPVASLEGDATDVEV
                     IKDLFHYLVSTLDLTVAKVDDFGNLIQLVDPISQDAILFEVSYTTIEFAFGKAETIQE
                     VENRFNNYMNVIQRKLAESNHAIVGCGIHPNWDKNENCPVAYPRYQMLMDYLNLSRNI
                     IKSDLHHFPEYGTFICGSQVQLDISKTNYLRVINAFTQIEAAKAYLFSNSEFSGADWD
                     TKISRDIFWEESMHGIYPENVGVNARLLNDEADFFDYLNHSAIFTAERDGQTYYFYPI
                     QAGDYLATSEIQAFALNGDEVIIYPQEKDFETHRSYQYQDLTTRGTVEFRSVCTQPLD
                     RTFASAAFHLGLLVNLDKLEAYLETAPFFKVFGYDYKSLRRQFSKKNLTDEEETTIIE
                     FSKDLLLLAEEGLVVRNKEEMTYLQPLREELSL"
     gene            complement(20410..20493)
                     /locus_tag="VQ540_001390"
     tRNA            complement(20410..20493)
                     /locus_tag="VQ540_001390"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20457..20459),aa:Leu,seq:caa)
     gene            complement(20503..20574)
                     /locus_tag="VQ540_001391"
     tRNA            complement(20503..20574)
                     /locus_tag="VQ540_001391"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20540..20542),aa:Gln,seq:ttg)
     gene            complement(20588..20660)
                     /locus_tag="VQ540_001392"
     tRNA            complement(20588..20660)
                     /locus_tag="VQ540_001392"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20625..20627),aa:His,seq:gtg)
     gene            complement(20675..20745)
                     /locus_tag="VQ540_001393"
     tRNA            complement(20675..20745)
                     /locus_tag="VQ540_001393"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20711..20713),aa:Trp,seq:cca)
     gene            complement(20750..20830)
                     /locus_tag="VQ540_001394"
     tRNA            complement(20750..20830)
                     /locus_tag="VQ540_001394"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20794..20796),aa:Tyr,seq:gta)
BASE COUNT         6237 a         4734 c         3669 g         6198 t
ORIGIN      
        1 tggtattatc aatcatgaac taggattcta gttttgcagg aagtctaata atgaaaataa
       61 aggactaaag caataactct aaatacatct gatttttata ggatatttca taaaaaaaat
      121 ctacatacct agagtcctat ttagttatgt atcttacata aagagaaagg aattaattat
      181 catgaaatta tctttgtata gtgaagttga acattaccat tttttaagtt cttattcttt
      241 aaatgatatt acatatactg ataccccaaa aaatattatt gaaaagtcta aaaaagataa
      301 gtatagatac ccaatagtaa tacttaataa agaccataaa gtaattggat ttttttgcct
      361 acacctaaac actggtccta aagagtatgg ctattatcaa aatgattatg cgcttattag
      421 aggattttct attcatgata atttcagaaa tcaaggatat ggttctaatg ctctgaatga
      481 aatatttgaa ttcatagact caactttaaa attagaaatt aaccatatta tattggctgt
      541 aaatgaaaaa aatatattgg ctcaaaaagc atatagaaat tccggttttt ctgttgtgaa
      601 aaaagattta gaaggaaaaa gggggaaatt aattattatg gagaaaagca gaaactagta
      661 atgatactag tttctgcttt tctctaagtc tgctataaat ttataacatg ttgaaataag
      721 atgtgaataa attgattgca gaattcaaac caatttctaa caatgtttta gaaaactcgg
      781 cggactattc cagattcaat ccactatatt ctatcttatt tgcatatttt gagagaaata
      841 atctatatac taaactttta tgtttataat tcattccttt cgtttcactc aaggcacaag
      901 acagaatgaa aaagtggtgt gctctttatt ttgttttata ataatagtga gaaaacctat
      961 cactactaca aatcacgggg aggtgaataa gtgagtggta tagccactac ctcgcatttt
     1021 tataggtgtc attctttcca tcaagcacaa gaactgtgac taggagcacg taaacttata
     1081 attgaataag cgactcgttt gtgaaaggaa agaatagtca agggataggc agactcaaat
     1141 ttggtgaagg gaaacccctc atgttaaaag ccaaacttca attttaaaaa ttttaaaatt
     1201 tgtttcgtat tcactactcc ttgcctttat attggattga ttaagagaac ctttcgcgtt
     1261 tctagaaact acagtggact attctggatt caacgcatta tagttgaatt gactaggaat
     1321 tctctttctt ttcaggcttc tcttctgatt tttttctccg ctttttcgct tgaatcagtc
     1381 gctacctctt cctttttatc cgttttctct tctttgattt tgactgaagg aaacagaaac
     1441 tcatattgac tcttatccgt acgaacagtc gtcaccaagc ttgttttctt gttttgatag
     1501 ctcacctgac ctagattaaa aacctgttcc ccactttctt gctcggcttt atccttggtt
     1561 cgtttagcca tggcaaaagc aaccaatttt tctttattta aagcatagtc ttgatagtgg
     1621 gcgatttgtc gggtcaaata aaattgcaac aaaagactaa agatggctgc tatggtgact
     1681 gcgtagagga gaacacctgc cttaactttc ttctttttcc acacgataga tgaactccct
     1741 ttctaagcct ttttgaaact ggaaacgaaa atgaaccagt tgattgtcct ctgtaatctg
     1801 agctgatttg aggccataaa ccataggctg atacccccgt ccactagcat cggttttacg
     1861 aaaatcgtct gactttgact taccgatggc gatgtccttg tcatcttgct tcatgtatag
     1921 gcgattgcct tctacttttt cgaactgcga acggtctaat tctgcctcaa gttggcccac
     1981 aaacaagagc cactcctttt gctcgctttg ttgctggtag cgaacttctg aaatgaggag
     2041 ctgactcata gcttgaaaaa ggagtaatcc cccactgatg acaatgaggg caagcaggga
     2101 ttctaacaag gtaaaagcct tgaccttatg gctctttgat tgccaacaac tgttctgaac
     2161 catggtagac ctccaatccc ttttcactag aaaatacctg aatctcaact ccgttgatgc
     2221 ttacctgatt ttgccccgtc tgcaaggcca tcttagctac cctcaagact tcttcctttt
     2281 gcaagatttt tgcttcctct tgcctatttt tttgaatttg tcccaaaagg agggtcgcaa
     2341 tgctggcaaa gatagctaga gcgactactg cttccagtaa aatcactgcc ctaatttttt
     2401 gtttccttaa tgcgtttaat ttttccattt cctagatata attgatagcg aatcgctcct
     2461 ttactggtct gaaattcaac cttagccagg gacgaattgc ccccagctcg gtcaaatgta
     2521 atactttggc ctgatggtgc ctgaattcct ttaggaactg tcaacttttg actgccattg
     2581 ctaatcatct gcccatccaa gttcagacta gtcttttgtt gactagctac actgcgtttt
     2641 tgggtttccc gatagagttc ttcaaactcc ataaagaaaa tctgttcctc taccgctgca
     2701 aaagtggact ggacagagcc ggacaagccc aaggcaagga tactcacaag tcccaaaacc
     2761 aagagacttt ccagcatggt aaaggcctta atcattgact ttacgatttg cccctccatt
     2821 tttagtatag tattcattat aagctttaac ctgttcttcc gtgatgcgcc catctccttg
     2881 taacttgctc agagtagcat cttcattttt atccaagcta taaagttctg cctggctttc
     2941 caccacctta acaacagctg cttttccttt gtcattgact gcttcttttt gcttggtcag
     3001 attaggtaca aagagcaaga aaagcacgct gataatcagc aagaccacca acatctccac
     3061 caatgtaaaa gctttaacct tagctttttt caagaatgtc atcatttttt tcattttaaa
     3121 aatttacctc catattttga tacatgggca tgagcattgc cgcataaagt aaaacgataa
     3181 tcagtgccac aaagataaaa accagtggct gcaccaaatt catggtgcgg ttgactcggg
     3241 taaaaaaggc ttcccaagtt ttttcagcat agatttccaa ctcactaccc agcttggact
     3301 taacttcccc atactctatg atgagactca attccttcct aaagaaagga taggttccta
     3361 tcgtctgaga aaattcacgg ccatttttca gggtttgagc cagatcttga ccgatttctt
     3421 taaagagctg ggaaccttgt tcctgcatca tttgaaaaat ctgcgtcagc tccattccct
     3481 gtgaaatcat attcccccat tcacgtgcat aataggctgt caagtaggtc tgcacaaaga
     3541 ttccaataaa gggaaggcgt gctaagatag aaaagacact catcttagaa cttcttttat
     3601 aaaaagttag tgctaaaagg gcaagcacgg aaacaagccc taccatgcct agaaaaattt
     3661 gtggcagatt accgataatt cgggtggcaa tattgctact atccagttgt gggagcaggt
     3721 aattccgtag ccccagcata attaagagaa gaaaatccag caaaatcaaa ggataggtcg
     3781 ctacttcaat taactttttc ttgaccttgg ccagattgtc tagatattct tctatctttc
     3841 ccaaactcag gtgaagattg ccatgaactt cagctagaga taactgagtg acaatggtac
     3901 ttgaacatcc caaactttcc atcatttctg agaatgattt cccctgagac aagcctgtac
     3961 gcatctgggt cacacactgc ttgtccaaca aggaactcct atctaaaaag gagatagtct
     4021 ccaccagatg aaaaccgcta gaaaagagat tgttaaatag ggtgatgata tttttttgct
     4081 tagctgtagc taattttttc cgtctcagcc tgaagacttg tgatatgtcc atctttaaga
     4141 agttggtcaa tttgctcatt ccacttggct gcttggtgtt cttgataatc tctgtttgca
     4201 aagtcaacga ttcctcctcc cccgattaat ctctggtagc agactccttg cagaacaact
     4261 gccaattctt cttcactcac acccaactcc agcagacgct cataaacacc tcggatactc
     4321 ttggcgtgaa tggttgaaaa gactgtcgca cctgtcaaac tagctctgac cactgcacgc
     4381 gccgtctcgc tgtcacgaat ttctccgata atcaagagat ctggtcgatg acgcaaggaa
     4441 agtttgatta gattttcata ggttaggccg attgcttcgt tcaactgcaa ctgaagcatg
     4501 tcgtcctgct tgatttcgac aggatcttcg atggacataa cttgctgtcc tttaaagagt
     4561 gacttggaca attcatgcat caaggtcgtc ttaccactcc caaccgggcc agcaaaaaga
     4621 tagagtcccc gttgcctgta ctgcttgcct aattcttcaa tatcctgaaa ccaaaaatgc
     4681 aagtcctgct cctcatcgtg caacaaacgg ataaccaaac tctcatgccc ccgataatcg
     4741 cctacagtag ataaacgtag agacgccatc ttctggtcat aggcataatc acaggaaccc
     4801 agttgactac gtcttttttc tcccacattc atacccgcca caaacttaaa gtgactgata
     4861 acggctgcaa acttttcaaa atcatagcta ccaattttac agcgctcgtc tcctaccctc
     4921 atatgaagct cataggcgtc taacttaggg acaaaataaa tatcctgcgt cccttttttc
     4981 cgagctgaac gaatgatttc ttgtgcaatt tcttgaacca tacttacctc ctcacctata
     5041 ctattcgcaa agcgttagaa aaataaaaaa agcaactcca aaaaagttac ttttctctat
     5101 tttaatttca tacggcaaga acgattcctt tcctgactgg tttgtttttc atagcctgag
     5161 cgtagttttt cgtctgggat aacctgctca tcctgcaaaa gagccaaaga atggtattgt
     5221 tgtaaatact catcacattc atcacaccag cgttggtctt ccgggtccca aaaaatggtc
     5281 atcaagtcgc ttctactttt ataaagaggg gattcttgtt ccaatctaaa ccagcaagtt
     5341 ttgtagtatt tgagagcatc ataatactgg tcaaattttc tacttgctac aatatcttct
     5401 tcccaacctt ctaagaacca ccacggttca aaatctccgt acatttctat aacacgatac
     5461 atattcattc attcctttgt accgtatatt ataaccaatt ccgccagaca aggaaagaaa
     5521 tatgctcatt tcttaatttt ttgataaaaa atccagccat ctgatggatg actgaatttc
     5581 tatttgctta tgtacaaaaa tatttttact acttaggctt ctgagatatc gttttcgata
     5641 atgaccttaa tggcatggtg gtctgctgcc ttactgaaga cttcgtaggc tttttcaatt
     5701 tcactgagtt tgaaatagtg agttaccaat ttttccggtt caatcttatg actttcaagt
     5761 gctttcaaca attgtggagt cgtatttgta gataccaaac cagttgttac attgatgttg
     5821 cgaatccaaa gtttatctaa atcgaattca actggtttac catgcacacc acagttggca
     5881 accgttccgt ctacaccgat aatcttttga cagaaatcaa atgtttcagg aatccctaca
     5941 gcttcgatag cgacatccac accacgacca tctgtcaaat cataaatttc tttaatggct
     6001 tttttagggt ctgaagaatt aaccttatga gtcgcaccga atgatagggc agtttccaag
     6061 cggttatcgt ctaggtctac cataatcaat ttagctggtg aatagaattg ggctgttaaa
     6121 agagcagcca atccaactgg acctgaacca ataatggcta cgctgcaacc aggttctact
     6181 ttccctttta agacaccaat ttcatatcca gtaggcagaa tgtctgacag cataaccaaa
     6241 gcttcatctg acaagtcttc tggagtatgg taaagagtat tatctgcatg agggacacgt
     6301 agatattcag cctgcatacc atcaatcaag tgaccgaaaa tccagccccc ttcgtcttca
     6361 cagtgggcat aaattccttt tttacagtag tagcatttac cacaggcaca gacgcaagaa
     6421 atcaagacct tgtcaccttt tttgaagttg gaaactcctt ccccaacttc ttcaacaatc
     6481 ccaatccctt cgtggccaag aatggtacca ctttggcaag taggaacatc ccctttgata
     6541 atatggaggt ctgttccaca aatagtggtt tttacaatac gcacaatagc gtctgttggc
     6601 ttgcgaataa ctggtttgtc tacatcaaca aaagaagcaa gtcctggttt aacataagta
     6661 taggctttca taaagcactc ctccgttttt ttatttgtaa tatttatagt tcaattgtaa
     6721 gcctttttct ttgtttcttc aagctttttt tgtgattttt ttaacttttt atttaccagt
     6781 aaagtaccct gtataaaaaa gcagaagcta gtctctaact tctgccttct ctcttatgct
     6841 tgataacgtt tcacaccatc taggtaggtt gctaccaatt ccaaatcttt atctaatacg
     6901 atgaagtcag cgtcgtagcc ttcacggatt tggccacaga cgtcatcgat gtgaacggat
     6961 ttagctgggt tgaagctggc catcatgact gcttcatgcg gattcgcaat tccccattcg
     7021 accacattct tcaaaccatc tttgagtttg aggatagaac ctgccaagtt acctgtcgat
     7081 ttgaggcgtg cagttccatt tgcaacgaca actgggaatt ctcccaacat ataatctccg
     7141 tcttccaatc ccccagctgt catacagtct gtgataagag cgatgttttc tgttcctttt
     7201 tgtttgataa gaatttcgca agcctttgga tctacgtggt gaccatcaca gatcaactct
     7261 gcataggtat gtggcaattg gtacatggct ccaaccatac ccaattcacg gtgagtcaac
     7321 ccacgcattc cattgtaggc atgcacccaa acactcgctc cagcatcgac tgcttttttg
     7381 gcttcatcaa aagtcgcgtt tgaatgtcca agagcaaccg tcacaccttc gcccgtaact
     7441 gtacgaacaa agtcttccac cccatcacgt tctggtgcaa gggcaatttt attaagcaag
     7501 ccatttgccg ctttttgcca agaatgaaac tcctcaacac ccgggtctct catataagtt
     7561 ggattttgtg cccccttaaa agtttctgtg aaatatggac cttcataata aatcccacga
     7621 atcttagcac ctgttgcttc tttataatgg tttccaagat tttcagtgac tgcaagcaat
     7681 tgctcataag tggctgttaa agttgtgggt aagaaactgg taacaccggt actaagaagt
     7741 ccttcactca tagtatgcaa tgtaccttca atgttgttgt ccatcacatc tacacctgca
     7801 tatccatgaa tatgagtatc cacaagtcct ggggcaatgc tataacctgt atagtcaatc
     7861 acctcagccc cttcaggaat ctgctctaca tgtttcccaa acttgccgtc cacaagttcc
     7921 aagtaaccac ctcgacgaac tccgtgtggg tagaaaaact gatccgcttt aatatagtta
     7981 ggcataatgt taacctcctt aaaagattga ttctacaatt tattatgtca attacattat
     8041 aaacctttct tttttatttg taaatggtat agacctattt tttggagata ttttaaaaga
     8101 gctggatttc tccaactctt ctctttttta atacaagtta ttttgattta accggcttgt
     8161 cttgagctgt ctgcaaagct gtggcaatcg tatctgcata caattttgct cctgcttcga
     8221 tagtgctact ctcactcccg aaatgaacct ggtctgttcc agcccaaatt tctggatgct
     8281 ctttcgcaac ttgattccaa tctgctatcg taatgtaagg tgtcttctct gccaattctc
     8341 tcatataggc agcagccttc tcaacgatgg cataggtctc ttttgtctta tctccctcat
     8401 aaggagtcac caaaatcata tggtgtccct taggaagatt tttcacgata ctgtcccagt
     8461 catccttgta attctcagga ttatttaccc cagtcgcaat gaccaccgtc ttaggtaaaa
     8521 atttattctg gctattattt agcatgattt catttgcggt cttggttgtt acgctgacct
     8581 gcgcgttaat ctgtgctcca ggaagagctg tctgtagtgc tgtatttgcc cttaaagcca
     8641 ctgagtcacc aattaacata gtgccatcag caattcccaa actgtttgca tctgcccgtt
     8701 ctgccatcac cttggtctgg ccaatatttg ttgcagcttg cttcaagcca ttgacagtca
     8761 agtctgtctc aaacgctccc acttgtggtg ccaacaaggt caccatgcag acaatgaagg
     8821 tcaagattcc tgtacctgct gcaagaattg cgtgaatata aggcagggga cgaagagttt
     8881 gtaaaatagg tgtgttcttg cctgcaatcc aaggttccaa tacataaaat gacagactgg
     8941 caaagccata agaacaaatc agagtcagta atacagcaag aagatttgat gtcaactgtg
     9001 agaaaatgat atagaaaggc caatggaaaa gataaaccgc atagctagta tccgctaaaa
     9061 agctgataat cttcggctcc tgtatatgat gtgtcttttc atgtaagaca cgcgccgcca
     9121 gaatcatggc aagagctgca agactggcaa gcaagaagcc gataagatag gcaaaaagat
     9181 aagtgaattt gacaaagaaa gtcaaaagaa ctaggaaacc aaagcctcct ccaaaaacta
     9241 ctaaagtctt tcgtaaatcc cagattttat ccaactgctt gacgagggaa gtcgtctgac
     9301 gaacgcctac aatagttgct aacatacttc ccaaaaagaa tggatagaca tgagttaaac
     9361 tggagaaata aacagaggaa taagaggtca ctagaaaact accaataaac atggagaaga
     9421 aactgatcaa gaaggcagta gcagataaga gaaagatcat ccccttcaac tgaccatttg
     9481 atttagcttg tttggataag aaccaaactg ccaatcccca aagaatatag tagtgaacct
     9541 caactgccaa actccaatta tgaacaaaca aatgaggaat gaactgagat tcataactcc
     9601 cacctgttaa gagttcatag aagttggtca taaagcctaa gacgcccgca atctggccac
     9661 caattccagc aacatagtct tggcgaacca agaaagtaaa aggcatggtc accaagacca
     9721 tcaaaaccac aggtggcaca atccgataaa agcgtcttct aaaaaatcct atcaaatcaa
     9781 tctcattgtt cttagaaaat tcttcaatga gtagagctgt aatcaggaaa cctgaaaatg
     9841 tgaaaaagac atctaccccg aaaaatcctc caggaaagat cgtctgaaag aagtgataca
     9901 agagtaccaa aagtaaacct ataatcctaa tcaaggaaaa ccatttaatg cgcatacgag
     9961 tttattcttc ctttcattgt acactttatt ctatcaaaaa aagaagaaaa atcctaagag
    10021 aaaacttagg atttttagct tatatcaatt ccattttaga aattacgtcc tgacttatta
    10081 tagccatatt tttccacaaa atacttacgg aattccaaga gattgtcatc catgatggct
    10141 tgtcgcactt gcttcatcag gttaagcaag aagtaaagat tgtggtagct agtcaagcgg
    10201 ataccaaagg tttcatcagc cttgagcagg tgacgaaggt aagcgcgtgt atagttatta
    10261 catgtgtagc aatcacactc aggatccagt ggcgtaaagt cctcagcaaa ctgggcattt
    10321 ttcacaacca aacgtccttg actggtcata caagtcccgt tacgagcaat tcgagtcggt
    10381 aagacacagt caaacatatc caccccacga atgaccccat cgatcaagct atctggcgct
    10441 cccacaccca tcagataacg aggtttattt tcaggcagca gttgagttgt aaagtccaag
    10501 accgcattca tctcttcatg ggtttctccc actgccaaac caccgataga gtagcctgag
    10561 aaatccatgc tgacaagatc gtgagctgat tggcggcgaa ggtcttcaaa tcctgcacct
    10621 tgcacaattc caaacaaacc ttggtcatgt ggacgacggt gagccttcaa accacactca
    10681 gcccaacggc tggtacgctc gatcgatttc ttaacgtagt cataaggttg ataaaactga
    10741 ggacattcat caaaggacat catgatgtct gaacccagat tattctgaat agagatggct
    10801 ttttctgggg ataggagcat cttagaacca tttagatgat ttttaaaggt tactccttct
    10861 tctgtgatat tacggctatc tgctaaagaa taaacctgaa aaccaccact atctgtcaag
    10921 ataggctggt cccaattcat gaacttgtgg agaccaccag cgcgtgcaat gagttcatct
    10981 ccagggcgaa gccagagatg ataggtgttt gataggataa ttcccgaacc catctccttc
    11041 aattcttcag gtgactgagt tttgacagtg gcttgtgtcc caactggcat aaacataggt
    11101 gtcggaaagg taccgtgggg agtgatgatt tctcctagac gagctcctgt gtgtttttct
    11161 ttcttaatca aacgatattt gattggtgaa tctgacattt tttacctccg aagctgggaa
    11221 agacagtccc agttcataca gtgtgcccaa ggacacactg tatgatttta tcaaaaaaag
    11281 taggaactgt cacgaactat gtataagaac tatggtataa taagagaatg aactatccaa
    11341 aaattgattt aaaaacaatt cgtcaggagt caaaacattt tcaggctgac accccccgtc
    11401 tctttctcct ctatatcctt cccagtatgc tggtcatctt atctggtttt cttaatccct
    11461 tatctcggat ccacgggact gttttagaac agccattttt cagcatactt ggccaaatac
    11521 ttcaaaccta cctctttcct ctactagtct cctttatcgg gactattctt ttgaccagtt
    11581 ccgtctatgc aacactgaca ctcatgaaag attctaaaac ggagccatct gtaaaaaaca
    11641 gcctagctct ctttgatgag gagcgctttt ctcaaacctt tttgacccta cttctcaaac
    11701 gtttctatct ctttttatgg agtatcccta atttacttgg gatttacctc ctcttttata
    11761 gtagcttttt agccaaaaaa ttcgtcaccc tacatcctga gtttccaaat ctagatctct
    11821 catcagttga aaccgagcgt ttcctcatgg tctttggact ctactttctt gcaagtctca
    11881 tcttgatcat tgtaggaaat atcctctata ttccacagta ttatgcctat tcacaggtgg
    11941 aatttcttct ctgttatagt ctagacctag gacaggtccc accaagacga atcctaaaaa
    12001 ctagccgttc ctttatgaag ggctacaagt tccagcactt tgtcctagat ttacagcttc
    12061 ttccttggta cttcctcaat tggattacct ttggcattgc tagtttttca ctcctacctt
    12121 atatccaatg cactaaaatt atgttttacc gagcagtatt ggctcgaaaa cgtccaaaag
    12181 cttgaaggtt tttcccctca agcttttttc tatcaatgag tttctccgcc taccaacttg
    12241 agttcctgat ctccatgttc tatcatagcg ccgattgctg cttctatccc tcgccgaata
    12301 tccactaaac tcatagttgg agtagtcggt ctgttcacca cctgttccat catataagga
    12361 atatgcataa aacctgcctt aacatatgga aatttctttt ctaccaaata gagagcctga
    12421 tacatcaaat ggctgcagac aaaagtccct gccgtattgg aaacagaggc cggtaagccc
    12481 tcttttttta tagcttgaac catcgcttta atcggcaaac tactaaagta ggccgaagca
    12541 ccatctgggc gaatgggacg gtcaatcggt tgattatctt cgttatcaga aatgcgtgca
    12601 tcgtcttgat taatggccac tcgttcaggt gtcacactag ttcttccacc agcttgccca
    12661 atacaaagga caaagtcagg ttgataacga ttcatctctt cttccaatac ttgagcagat
    12721 ttgtgaaaaa ctgtcggcac ctctagccaa cggacctcag caccatggat ttcagctggt
    12781 aaacctttaa tggcctccaa agttggattg cccttttccc ctccaaaggg ctcaaaacct
    12841 gtcactaata ctttcatttc taactcctca aaaccaattc aatgagactt ttttcttaaa
    12901 aacaagtata acatatttcc cttattctgg attaaaaagg attagcgaga ttaaaatcga
    12961 ccttcaagtg tatttaaaga gtaaaatact aatcaaggcc aaaatagctg atccaccttg
    13021 cttcaaaata atttttttat ccgctgttaa agagccgtaa gtcgcagcac caatcacaaa
    13081 taagacaaaa atagtcacaa tttctaaatt ctgtgagaaa taaatgccat accagagaaa
    13141 gactcctagc agagccttat aaatcccttg atttttgaac aatgaactta ctgacggatg
    13201 agccaattct tccttttcca tattaaatac acgactagtc gcatctgatc gcgtagcaat
    13261 actttccaaa taaaaaatgt aaaaatgctc caaagcaacg atcgttgtta aaataattgt
    13321 aataattgac atctatttct ccttaaattt ctatattttc aatacccaaa accaatttat
    13381 ttaataaacg gctgagttct gttctctcaa actctgttaa gatactttcc atctcttcct
    13441 taaccttgat atgttgcaga gggggattca ccactaactg ctccttggca tacttcgcag
    13501 cctctaccaa cacttcccgc tgattttcag gattacgatg acgctccacc aaaccttccg
    13561 tttccaaaat cttgaaatgc cgtgtcaaag cagcctgatc aattttcaaa cgctcctgaa
    13621 ccgccatttg gttacaagga gaatgctcca gcaaaaacag taaaatctga taccgtgtca
    13681 aactaatccc aagccttttt tcaaacaatt gcgtactcgc ttgctcagac aagcggagtt
    13741 gatacagtaa atcttgaatc tctatcattt cttcctccta tccattgact tatcaatagt
    13801 tgaccaatca attataatat aaagtatagt gaaatgaaat aagagcagga caaatcgatc
    13861 aggacagtca aatcgatttc taacaatgtt ttagaagcag ttgtgtacta ttctagtttc
    13921 aatctactat aaaatagatt gcaagaatgt tgcttagatt attacaagat gataactttc
    13981 cattttccat tcaaattgat actcaatgaa aatcaaaaag caaactagga agctagtcgc
    14041 aggttgctca aagcacagct ttgaggtttc agataaaact gacgtggttt gaagagattt
    14101 tcgaagagta tgacaaagaa aaaacgaacg agaatcgctt cccatcacga aagctagatc
    14161 tcattcgtca aaatgatgtt accaagtcgg gtttatccat tcattgaaac gtgaacgtga
    14221 tcatagtgat tttctgtcac actaccacgg tctggcattg ggttccaagt gttagctggc
    14281 ccatatttgc tatcgaatgg agcatagaaa cgttgtttcc agatgatgta actaatgcca
    14341 cggctggcca tgttttgaat agcatattcc gcaatcttat cccctaattc tgaacgttct
    14401 ggtaccataa agtcgatagc caaacctttt ccgtgatctc cactgtctcc tggacgataa
    14461 ccgctaaagg atgtaatgcc aaacaagtta gcaatttctt ctttaaaggc agctgtttgt
    14521 ggttgaagac ctgcattttc agattttgct actgcaagtc cagcataatc gggcgcagct
    14581 ggagcctcgt aagttgttga aattattttc gtctcttctg gttgataagt agaaactgct
    14641 gctgtagctc catttgatga tgctacttct tttgcttctg aacttgttgt agttgcttcc
    14701 actgctgatg cagcttgagg gcttgcttgt gtttcctgct tctcagctgg agtcgttccc
    14761 tgaggagctt cttctgcaac tgcactgctt gtttcggccg tttgctcctc tgggacagaa
    14821 gtgcccgtag atggtgccac ttcttcagaa gcaatcactg tctttgtaac ttctgaactt
    14881 gatgctactt cttttggagc ttctgcaatt ggttgagaaa ggtctgcaac ctgaacagtt
    14941 tgatcatcaa cggtcacttg attagtggtc aaatctgctg tcgcagttgt cacttcttca
    15001 ctagagtctg cttgaggtgt ttggatttca acttctgtta cttcttctgc ttcattgaca
    15061 gtcgttgtca aaacagtttc tgggaaaatc aagtccatat tagtgatttt gttcagattc
    15121 gcaagcactg tgacatctac acccaaggct tctgcaatgg tgctcaaagt atcaccatac
    15181 tgtacggtat aacttgtttt gttgtccgtt ttagtcaaat cgttttggat ttgctcaaca
    15241 ctacgtgcag tccaaagaac ttcttctgct tgagttgcca atactggggc aaatgacaag
    15301 gctactgttg acgctaataa cattcttttc ttcattcttt caaattcctt tcaaatgagt
    15361 acctgtctat cataacacaa aaaatgtaga aaaaaagccc tctcgggcct atttaacaga
    15421 actgtctatt ccttgtaaca aactagatta cttgaaatag tttgttaggt ctctgtcaca
    15481 aaactgacac aatcttttta tcacttagtc tcaaaaatac gggaaatatc tgctaacgct
    15541 tgaatcctgt gattcccttc ataagtagac tctaaaaagt tgatactttg aatcccacta
    15601 ttctgggcaa attccacatc cagagtccga tcccctatat aataagtatt atcagaattc
    15661 aactgatact tatctagcag ataggtagcc gcttctggac ttggcttccg cacaaagcca
    15721 ctctgactgg tcaaaatctc tgtaaaatag gattccaccc ccaagtcctt gagaatggta
    15781 aaagtgttgt tccccttatg agtatatata aactgctgaa ttcctgattc gtctgcccaa
    15841 gctagcacct cacgcgcacc tggcatcaaa actacctgag cattcttctc agccagactc
    15901 tgggcacgca cctgatttag cacctcaaca tccagatttc tatcttctgc cacccgcaca
    15961 agcaaatttt gcaccgaata cttgaagata aactctctca ccttctcctt atcataagga
    16021 atagaaaact gagcaaaagt ctcctcaatc cctgataaaa tcgcttcgta agagtccaat
    16081 aaagtcccgt ctaaatccca aataaaagct gttttttgca tttcctatcc tttcaagctc
    16141 atatagcgct ggtaacgata gcgtagaaat aaccagcgaa aaccattatc caagagagac
    16201 cctgcccaaa taccaggcaa gccccaacca agcacaatac ccatcagata tcctgtccca
    16261 atgcggatac accacatgcc tatacttgtc gcataaaaag ggaggcgtgc atttcctaat
    16321 ccctgccaga ctgccgtata gatgactgtt cctgtcgtca taggggtacc aagtagtgaa
    16381 aacagtgtca ctagaacact agcctccacc gctagagaat cagtcgtata gagatgagtt
    16441 aatggtacac ccaagacata tatactaaag gacaggggca acatgaggaa cagagaaagc
    16501 caaaaggttt gtttactcaa actagcaact cttttccaat catcctctcc aactgctcgg
    16561 gccaacagca tgaccgttgc cgtagcgaca ccaaaggcag gcatatagtt aaactgggtc
    16621 aagacttctc cgattgcatt cccagcaact gcctccgtcc caaaagaaac gaccaaggca
    16681 atgatcacta catctccagc cctcatcata agtcgctctc cagctgctgg taaagccaag
    16741 gtcaacagtt ccttatctaa accaaaagtt agcttcccat aaggcagttt taattgtgac
    16801 cacaaaatca caagaccaac caaacgagac agaattgtcc cccaagcaac accagctatc
    16861 cccatatcca gaacaaaaat agctagactt gaaaaaagaa tattcaaggc attggataaa
    16921 aaactaacat agagaggcag acgtggatta tgcgttgcac gaatcaaggc tcccaaacta
    16981 gtcattaaac ctaagagaac aatcgatccg cctaccaaag atagatacag tccaccactc
    17041 tcagctacat ccctctccgt ccccaaaagt cctatcatct ctttcccagc gaagatggac
    17101 aaaaatccta aaaggaaact taatagtaag gtaatcttca acgcctcagt cacatgatag
    17161 gccaacttcg actggtcttt ctgccctatg ctttttgaaa taacactgga aatagcagct
    17221 cccagagcga tgaaaatcgc ctgataaatg gtgataatat taccagctac tgaaacccct
    17281 gaaatagcta tcaatcctaa atgagcaacc aaataactgt ccaccattcc cattagcatc
    17341 tgcaaaaagt tttcacccat agctggcaat gcaatattaa gaatgtcttt atttttctta
    17401 aacaatctct cctcctgatg aaaagaaact cagttggttt cccaaccgag tttgctccct
    17461 ctgtcttaaa gtcctaaata agcctcaacc gctgcttgca tgtcagcagc tgccactgtt
    17521 gtcttgtgac gaattggagc tatttcaagc ccatcaactg ctggtggcac tgcaacgcct
    17581 gagatttcat gtaattgagc caaggcttca aagtctgtca aacctgcttt tccagttaca
    17641 gcttctactg caactactgg gaacttgtat ggactagctg ttgaagcaat cactgtctta
    17701 gttacatctc cagtaaccgc ttggtatttt ctataaactg ctgaggcaac cgccgtatgt
    17761 ggatcctcaa tataagaatc tgactcataa acacgcttga tttctgccgc tgtttcttcc
    17821 tcagtcgcat attcagctgc aaagaggtcc aaaatctctg catcaaagtc tgtcaactta
    17881 tattgtcctt gcgtgttcaa ggcattcata agttcagctg tcttttcagc attatttccc
    17941 aaaagatgga aaatcaagcg ctccaagttt gaagatacca agatatccat agatgggctg
    18001 gttgttacct taaactcacg ttttttgtca tagacacgtg ttttaaagaa gtctgtcaag
    18061 acattattgt catttgaagc acagattagc ttgccaactg gtaggccgat ttgtttggca
    18121 taaaaggcag ccaagatatt tccaaagttt cctgttggta ctgtgaagtt aaccttttca
    18181 ccagctacaa tttcaccagt cttaaccaat tgagcgtaag cataaacata ataaacaatt
    18241 tgtggcacca gacgaccaat gttcatagag ttagctgatg aaaattgcaa cttgttggta
    18301 gtcaattttt cacgaagagc cacgtcgtta aacatgtgct tcacatttgt ttgcgcatcg
    18361 tcaaaattac catcaatagc aataacatga gtattgtcac cattctgagt ggtcatttgc
    18421 aactcttgta ccttgctgac accacccttt ggataaaaga cgataatctc agtaccaggc
    18481 acatccgcaa accccgccat agcagctttc cccgtgtcac cagatgtcgc tgtcaagata
    18541 acaatcttgt tctccaaacc atgtttctta gcagcagtcg tcataaagta tggcaaaata
    18601 gacaaggcca tatccttaaa ggcaatcgtt gaaccatgga aaagttccaa attgtattgc
    18661 ccatctaatt tcactaatgg tgcaatagct ggagtatcaa atttgctatc gtaggcattg
    18721 ttgatacagt agtccaactc ctcagctgta aagtcatcta aaaatgctga caaaactagc
    18781 ttagcaactt cctggtaaga agcatctttc aatttgtcaa agtccaaatc tacctttgga
    18841 taagtaaccg gtgtaaacaa accgccgtcc gtcgccaaac cttgcaaaat tgcttggctg
    18901 gcagttactg tattgttggc atcacgcgtt gattgataaa ctaatgtcat tactctctat
    18961 cctttatcta tagtctcgtc cattatatca tgatttttca gaaaattctc cctttataag
    19021 agaaattata ggctcaattc ttctctcaaa ggctgtaaat aggtcatttc ttccttattt
    19081 ctcaccacta gtccctcctc agctagtagg agtaagtctt tggaaaattc aataatcgta
    19141 gtttcttcct catctgtaag atttttctta gaaaattgtc tccttaaaga cttgtaatca
    19201 taaccaaata ctttaaagaa aggtgctgtt tctaagtaag cttctaactt gtctaaatta
    19261 accaataatc ccaagtgaaa agctgcagaa gcaaaagtcc tatcaagtgg ctgtgtacac
    19321 acactacgaa actcaactgt tcctcgagtc gttaaatctt ggtactggta actacgatga
    19381 gtttcaaaat ccttctcttg ggggtaaata ataacctcat ccccattcag agcaaatgct
    19441 tggatttcgg acgtagccaa atagtcccca gcctgaatag gataaaaata ataggtctgc
    19501 ccatcacgtt ccgcagtaaa aatcgcagaa tgatttagat agtcaaaaaa atcagcttca
    19561 tcattaagga gtctagcatt gaccccaaca ttctctggat agataccatg catagattct
    19621 tcccagaaaa tatcccttga aattttcgta tcccaatccg cacccgaaaa ttcagagttt
    19681 gaaaataaat aagccttagc cgcttcaatt tgagtaaaag cattaatcac ccgtaagtag
    19741 ttggtttttg aaatatccag ctgaacctgg ctcccacaga taaaagtacc atattcaggg
    19801 aaatgatgta aatctgattt aataatattt ctactcaaat tcaaataatc catcaacatc
    19861 tgatagcgtg gataagccac tggacaattc tcatttttat cccagttggg atggatacca
    19921 cagccaacaa tagcatgatt tgattcagct aactttctct gaattacatt catataatta
    19981 ttgaaacgat tttcgacctc ttgaatcgtt tcagccttac caaatgcaaa ctcaatcgtt
    20041 gtataggaaa cttcaaataa aatagcatcc tgacttatcg gatctactaa ctggatcaga
    20101 ttgccaaaat catctacctt tgctacggtg agatccaaag tagaaactaa ataatgaaat
    20161 agatccttta taacttcaac atctgtagca tccccttcta aacttgcaac aggatactcc
    20221 aactcaattc cgacaaacaa ttcaggattt tctttaatat ttttcaaata ccgatgtttt
    20281 aataaatcga tagaacaaga catactaccc tacactttct taatctaaat aaaatttgaa
    20341 taactataat tataccaaaa ataatataaa aaaggaacga agaataacaa cgttcctaac
    20401 actatactat accggcggcc ggggtcgaac cggcacgtcc ttgcggacac tggattttga
    20461 gtccagcgcg tctgccaatt ccgccacgcc ggcaaatagt aactggggta gctggattcg
    20521 aaccaacgca tgagggagtc aaagtccctt gccttaccgc ttggctatac cccaataata
    20581 taaaataggc gagtgatggg gatcgaaccc acgcatgcca gagccacaat ctggtgtgtt
    20641 aaccacttca ccacacccgc cataattcta ttaacacggg cagtaggaat tgaacccaca
    20701 ctgaaggttt tggagacctt agttctacct ttaaactatg cccgtaaaat ggaaggggag
    20761 ggattcgaac ccccgaaccc gaaggagcgg atttacagtc cgccgcgttt agcctcttcg
    20821 ctacccttcc aaaatata
//
LOCUS       DAVBDR010000038        19924 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.038, whole genome shotgun sequence.
ACCESSION   DAVBDR010000038 DAVBDR010000000
VERSION     DAVBDR010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 19924)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19924)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19924
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.038"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            complement(<1..617)
                     /locus_tag="VQ540_001395"
     CDS             complement(<1..617)
                     /locus_tag="VQ540_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HET2545187.1"
                     /translation="MDFEYFYNREAERFNFLKVPEILVDREEFRGLSAEAIILYSILL
                     KQTGMSFKNNWIDKEGRVFIYFTVEEIMKRRNISKPTAIKTLDELDVKKGIGLIERVR
                     LGLGKPNIIYVKDFMSIFQVKENDLQKSKNLTSEVKDFNLRSKENELQEVKNLDSNYI
                     ENNKSKYSKREYSFGENGLGTFQNVFLAAEDISDLQIIMNSQLEN"
     gene            complement(726..1244)
                     /locus_tag="VQ540_001396"
     CDS             complement(726..1244)
                     /locus_tag="VQ540_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013852041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClbS/DfsB family four-helix bundle protein"
                     /protein_id="HET2545188.1"
                     /translation="MRTYENKEELKAEIEKTFEKYILEFDNIPENLKDKRADEVDRTP
                     AENLAYQVGWTNLVLKWEEDERKGLQVKTPSDKFKWNQLGELYQWFTDTYAHLSLQEL
                     KAKLNENINSISAMIDSLSEEELFEPHMRKWADEATKTATWEVYKFIHVNTVAPFGTF
                     RTKIRKWKKIVL"
     gene            complement(1471..2340)
                     /gene="rsmI"
                     /locus_tag="VQ540_001397"
     CDS             complement(1471..2340)
                     /gene="rsmI"
                     /locus_tag="VQ540_001397"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001166894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HET2545189.1"
                     /translation="MQIQKSFKGQSPYGKLYLVATPIGNLDDMTFRAIQTLKEVDWIA
                     AEDTRNTGLLLKHFDISTKQISFHEHNAKEKIPDLIGFLKAGQSIAQVSDAGLPSISD
                     PGHDLVKAAIEEEIAVVTVPGTSAGISALIASGLAPQPHIFYGFLPRKSGQQKQFFGS
                     KKDYPETQIFYESPHRVADTLENMLEVYGDRSVVLVRELTKIYEEYQRGTISELLESI
                     AETPLKGECLLIVEGASQDVEEKDEEDLFLEIQARIQQGMKKNQAIKEVAKIYQWNKS
                     QLYAAYHDWEEKQ"
     gene            complement(2343..2660)
                     /gene="yabA"
                     /locus_tag="VQ540_001398"
     CDS             complement(2343..2660)
                     /gene="yabA"
                     /locus_tag="VQ540_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HET2545190.1"
                     /translation="MDKKELFDALDDFSQQLLVTLADVEAIKKNLKSLVEENTALRLE
                     NSKLRERLGEVEADAPVKAKHVRESVRRIYRDGFHVCNDFYGQRREQDEECMFCDELL
                     YRE"
     gene            complement(2700..3590)
                     /locus_tag="VQ540_001399"
     CDS             complement(2700..3590)
                     /locus_tag="VQ540_001399"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HET2545191.1"
                     /translation="MKQDQLKAWQPAQFDRFVRILEQDQLNHAYLFSGFFGSLEMAQF
                     LAKSLFCTDKVGVLPCEKCRSCKLIEQEEFPDVTLIKPVNQVIKTERIRELVGQFSQA
                     GIESQQQVFIIEQADKMHPNAANSLLKVIEEPQSEVYIFFLTSDEEKMLPTIRSRTQI
                     FHFKKQEEKLILLLEQMGLVKKKATLLAKFSQSRAEAEKLANQASFWTLVDESERLLT
                     WLVAKKKESYLQVAKLANLADDKEKQDQVLRILEVLCGQDLLQVRVRVILQDLLEARK
                     MWQANVSFQNAMEYLVLKEI"
     gene            complement(3587..4225)
                     /locus_tag="VQ540_001400"
     CDS             complement(3587..4225)
                     /locus_tag="VQ540_001400"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HET2545192.1"
                     /translation="MSKGFLVSLEGPEGAGKTSVLEALLPILEEKGVKVLTTREPGGV
                     LIGEKIREVILDPSHTQMDAKTELLLYIASRRQHLVEKVLPALEAGKLVIMDRFIDSS
                     VAYQGFGRGLDIEAIDWLNQFATDGLKPDLTLYFDIEVEEGLARIAANSDREVNRLDL
                     EGLDLHKKVRQGYLSLLDKEGNRIVKIDASLPLEQVVETTKAVLFDGMGLAK"
     gene            complement(4445..5242)
                     /gene="proC"
                     /locus_tag="VQ540_001401"
     CDS             complement(4445..5242)
                     /gene="proC"
                     /locus_tag="VQ540_001401"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HET2545193.1"
                     /translation="MKIGFIGLGNMGASLTKSVLQARPSDEILLANRSQVKVDAFIAN
                     FGGQTSNNEEIFEEADVIFLGVKPAQFSELLSQYQTILEKRESLLLISMAAGLTLEKL
                     ASLIPSQHRIIRMMPNTPASIGQGVISYALSPNCRAEDSEIFCQLLAKAGLLVELGES
                     LINAATGLAGCGPAFVYLFIEALADAGVQTGLPRETALKMAAQTVVGAGQLVLESQQH
                     PGVLKDQVCSPGGSTIAGVASLEAHAFRGTVMEAVHQAYKRTQELGK"
     gene            complement(5246..6508)
                     /locus_tag="VQ540_001402"
     CDS             complement(5246..6508)
                     /locus_tag="VQ540_001402"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HET2545194.1"
                     /translation="MVSRQEQFEQVQAVKKSINTASEEVKNQALLAMADHLVAATEEI
                     LAANALDMAAAKGKISDVMLDRLYLDADRIEAMARGIREVVALPDPIGEVLETSQLEN
                     GLVITKKRVAMGVIGIIYESRPNVTSDAAALTLKSGNAVVLRSGKDAYQTTHAIVTAL
                     KKGLETTTIHPNVIQLVEDTSRESSYAMMKAKGYLDLLIPRGGAGLINAVVENAIVPV
                     IETGTGIVHVYVDKDADEDKALSIINNAKTSRPSVCNAMEVLLVHENKAVSFLPRLEQ
                     VLVADRKEAGLEPIQFRLDSKASQFVSGQAAQAQDFDTEFLDYILAVKVVSSLEEAVA
                     HIESHSTHHSDAIVTENAEAAAYFTDQVDSAAVYVNASTRFTDGGQFGLGCEMGISTQ
                     KLHARGPMGLKELTSYKYVVTGDGQIRE"
     gene            complement(6518..7648)
                     /locus_tag="VQ540_001403"
     CDS             complement(6518..7648)
                     /locus_tag="VQ540_001403"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004240022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HET2545195.1"
                     /translation="MNNRSETMKYKRIVFKVGTSSLTNEDGSLSRSKVKDITQQLAML
                     HEAGHELILVSSGAIAAGFGALGFKKRPTKIADKQASAAVGQGLLLEEYTTNLLLRQI
                     VSAQILLTQDDFVDKRRYKNAHQALSVLLNRGAIPIINENDSVVIDELKVGDNDTLSA
                     QVAAMVQADLLVFLTDVDGLYTGNPNSDPRAKRLERIETINREIIDMAGGAGSSNGTG
                     GMLTKIKAATIATESGVPVYICSSLKSDSMVEAAEETEDGSYFVAQEKGLRTQKQWLA
                     FYAQSQGSIWVDKGAAEALSQHGKSLLLSGIVEAEGVFSYGDIVTVFDKESGKSLGKG
                     RVQFGASALEDMLRFQKAKGVLIYRDDWISITPEIQLLFTEF"
     gene            complement(7731..9611)
                     /gene="cbpE"
                     /locus_tag="VQ540_001404"
                     /gene_synonym="pce"
     CDS             complement(7731..9611)
                     /gene="cbpE"
                     /locus_tag="VQ540_001404"
                     /gene_synonym="pce"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine esterase CbpE"
                     /protein_id="HET2545196.1"
                     /translation="MKKKLTSLALVGAFLGLSWYGNVQAQESSGNKIHFINVQEGGSD
                     AIILESNGHFAMVDTGEDYDFPDGSDSRYPWREGIETSYKHVLTDRVFRRLKELGVQK
                     LDFILVTHTHSDHIGNVDELLSTYPVDRVYLKKYSDSRITNSERLWDNLYGYDKVLQT
                     AAEKGVSVIQNITQGDAHFQFGDMDIQLYNYENETDSSGELKKIWDDNSNSLISVVKV
                     NGKKIYLGGDLDNVHGAEDKYGPLIGKVDLMKFNHHHDTNKSNTKDFIKNLSPSLIVQ
                     TSDSLPWKNGVDSEYVNWLKERGIERINAASKDYDATVFDIRKDGFVNISTSYKPIPS
                     FQAGWHKSAYGNWWYQAPDSTGEYAVGWNEIEGEWYYFNQTGILLQNQWKKWNNHWFY
                     LTDSGASAKNWKKIDGIWYYFNKENQMEIGWVQDKEQWYYLDVDGSMKTGWLQYKGQW
                     YYFAPSGEMKTGWVKDKEAWYYMDSTGIMKTGEIEVAGHHYYLEESGAMKQGWLKKAN
                     DWYFYKTGGSRAIGWIKDKDKWYFLKENGQLLVNGKTPEGYTVDSSGAWLVDVPIEKS
                     ATIKTTSHSEIKESKEVVKKDLENKETSQHESVTNSSTSQDLTSSTSQSSETSVNKSE
                     SE"
     gene            complement(9614..10501)
                     /locus_tag="VQ540_001405"
     CDS             complement(9614..10501)
                     /locus_tag="VQ540_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HET2545197.1"
                     /translation="MEIKIETGGLRLDKALSDLSELSRSLANEQIKSGQVLVNGQVKK
                     AKYTVQEGDVVTYHVPEPEVLEYVAEDLPLEIVYQDEDVAVVNKPQGMVVHPSAGHTS
                     GTLVNALMYHIKDLSGINGVLRPGIVHRIDKDTSGLLMIAKNDDAHLVLAQELKDKKS
                     LRKYWAIVHGNLPNDRGVIEAPIGRSEKDRKKQAVTAKGKPAVTRFHVLERFGDYSLV
                     ELQLETGRTHQIRVHMAYIGHPVAGDEVYGPRKTLKGHGQFLHAKTLGFTHPRTGKTL
                     EFKADIPEIFKETLERLRK"
     gene            complement(10491..10952)
                     /locus_tag="VQ540_001406"
     CDS             complement(10491..10952)
                     /locus_tag="VQ540_001406"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HET2545198.1"
                     /translation="MKKRAIVAVIVLLLIGLDQLVKSYIVQQIPLGEVRSWIPNFVSL
                     TYLQNRGAAFSILQDQQLLFAVITLVVVIGAIWYLHKHMEDSFWMFLGLTLIIAGGLG
                     NFIDRVSQGFVVDMFHLDFINFAIFNVADSYLTVGVIILLIAMLKEEINGN"
     gene            complement(10949..11857)
                     /locus_tag="VQ540_001407"
     CDS             complement(10949..11857)
                     /locus_tag="VQ540_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001025716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HET2545199.1"
                     /translation="MNIQQLRYVVAIANSGTFREAAEKMYVSQPSLSISVRDLEKELG
                     FKIFRRTSSGTFLTRRGMEFYEKAQELVKGFDIFQNQYANPEEEKDEFSVASQHYDFL
                     PPTITAFSERYPDYKNFRIFESTTVQILDEVAQGHSEIGIIYLNNQNKKGIMQRVEKL
                     GLEVIELIPFHTHIYLCEGHPLAQKEELVMEDLADLPTVRFTQEKDEYLYYSENFVDT
                     SASSQMFNVTDRATLNGILERTDAYATGSGFLDSDSVNGITVIRLKDNLDNRMVYVKR
                     EEVELSQAGTLFVEVMQEYFDQKRKS"
     gene            11850..12047
                     /locus_tag="VQ540_001408"
     CDS             11850..12047
                     /locus_tag="VQ540_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET2545200.1"
                     /translation="MFIFYPQLLYLFIIPYFRSFPKRKKEHPILLNYLHYLPFSRQSY
                     FQNQFKKISGYTPLQYRKEKR"
     gene            complement(12099..12770)
                     /locus_tag="VQ540_001409"
     CDS             complement(12099..12770)
                     /locus_tag="VQ540_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET2545201.1"
                     /translation="MKKRAIQILLALSLIFYKSTWFWRVFNHLAKPYLPASREFFQIL
                     LLMESGVLFLAVIYLLVFAGKKIFHFKWQLRYFIYLLLGYIISYMSDFLFSYFISLSS
                     NQISLNETVEMMGRQEFPYFLLIVCFIAPIAEELIYRGVLMTTFFKNSPWYGDVLLSA
                     IIFGYIHINFALTPLAFFIYASGGLILALLYRMTKNLYYPILVHILINITAFWDVWLL
                     LFSGS"
     gene            complement(12824..13045)
                     /locus_tag="VQ540_001410"
     CDS             complement(12824..13045)
                     /locus_tag="VQ540_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000602450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0924 family bacteriocin-like peptide"
                     /protein_id="HET2545202.1"
                     /translation="MILMTKNINLTNEELELIQGGADSYGKNPNGRYDWEIEPVLTLP
                     VHGFCPRGTYDLGYIGGGNHLCKGSAARF"
     gene            13317..14126
                     /locus_tag="VQ540_001411"
     CDS             13317..14126
                     /locus_tag="VQ540_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000593565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HET2545203.1"
                     /translation="MIKLLALDMDGTLLNEAKEIPQAHITAIHKAIEKGVKLVLCTGR
                     PLFGVLPYYKKLGLDLQNEYVIVNNGCSTHQTSDWGLVDWQELSPADIEYLYDLAEKS
                     DVQLTLFDESHYFVLGGKPNQVIENDAKLVFSDLTEISLEEATSGKFRMFQGMFLGTK
                     EQTDDFEQRFAEELCQRFSGVRSQPVIYEAMPLGTTKATALSRLAEILKIDSSEIMAM
                     GDANNDIEMLQFAGLGIAMGNASDYVKSLADAVTSSNEEDGVARAIEKYIL"
     gene            complement(14307..15182)
                     /gene="aguB"
                     /locus_tag="VQ540_001412"
     CDS             complement(14307..15182)
                     /gene="aguB"
                     /locus_tag="VQ540_001412"
                     /EC_number="3.5.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001246759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-carbamoylputrescine amidase"
                     /protein_id="HET2545204.1"
                     /translation="MRNVRVATIQMQCAKDVATNIQTAERLVRQAAEQGAQIILLPEL
                     FEHPYFCQERQYDYYQYAQSVAENTAIQHFKLLAKELQVVLPISFYEKDGNVLYNSIA
                     VIDADGEVLGVYRKTHIPDDHYYQEKFYFTPGNTGFKVWNTRYAKIGIGICWDQWFPE
                     TARCLALNGAELLFYPTAIGSEPILDTDSCGHWQRTMQGHAAANIVPVIAANRYGLEE
                     VTPSEENGGQSSSLDFYGSSFMTDETGAILERAERQEEAVLLATYNLDKGASERLNWG
                     LFRDRRPEMYRQITD"
     gene            complement(15192..16277)
                     /gene="aguA"
                     /locus_tag="VQ540_001413"
     CDS             complement(15192..16277)
                     /gene="aguA"
                     /locus_tag="VQ540_001413"
                     /EC_number="3.5.3.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="agmatine deiminase"
                     /protein_id="HET2545205.1"
                     /translation="MMDSPKKLGYHMPAEYEPHHGTLMIWPTRPGSWPFQGKAAKRAF
                     TQIIETIAEGERVYLLVEQAYLSEAQSYLGDKVVYLDIPTNDAWARDTGPTILVNDKG
                     KKLAVDWAFNAWGGTYDGLYQDYEEDDQVASRFAEALERPVYDAKPFVLEGGAIHSDG
                     QGTILVTESCLLSPGRNPNLTKEEIENTLLESLGAEKVIWLPYGIYQDETNEHVDNVV
                     AFVGPAEVVLAWTDDENDPQYAMSKADLELLEQETDAKGCHFTIHKLPIPAVRQVVTE
                     EDLPGYIYEEGEEERYAGERLAASYVNFYIANKAVLVPQFEDVNDQVALDILSKCFPD
                     RKVVGIPARDILLGGGNIHCITQQIPE"
     gene            complement(16274..17401)
                     /gene="nspC"
                     /locus_tag="VQ540_001414"
     CDS             complement(16274..17401)
                     /gene="nspC"
                     /locus_tag="VQ540_001414"
                     /EC_number="4.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxynorspermidine decarboxylase"
                     /protein_id="HET2545206.1"
                     /translation="MKLEQVPTPAYVIDLAKLEANCRILQYVQEEAGCKVLLAQKAYS
                     LYKTYPLISQYLSGTTASGLYEAKLAREEFPGEVHVFAPAFKDEDMEELLGITDHIVF
                     NSERQLRKHGARCREAGVSVGLRLNPQCSTQGDHALYDPCAPGSRFGVTIDKIPSDLL
                     DLVDGLHFHTLCEQGADDLQTTLKAVEEQFGPYLHEVKWLNMGGGHHITREGYDVDLL
                     ISEIKRIRKTYNLEIYIEPGEAIALNAGYLATEVLDIVENGMEILVLDASATCHMPDV
                     LEMPYRPPLRNGFESQEKAHTYRLSSNTCLTGDVIGDYSFENPVQIGDRLYFQDMAIY
                     SFVKNNTFNGIGLPSLYLMDEQGDCSLLKAFGYQDFKGRLS"
     gene            complement(17401..18660)
                     /locus_tag="VQ540_001415"
     CDS             complement(17401..18660)
                     /locus_tag="VQ540_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000088792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="saccharopine dehydrogenase family protein"
                     /protein_id="HET2545207.1"
                     /translation="MSRLLVIGCGGVAQVAISKICQDSETFTEIMIASRTKSKCDDLK
                     AKLEGKTSTKIETAALDADKVEEVIALIESYKPEAVLNVALPYQDLTIMDACLATGVH
                     YIDTANYEAEDTEDPEWRAIYEKRCKELGFTAYFDYSWQWAYQEKFKEAGLTALLGSG
                     FDPGVTSVFSAYALKHYFDEIHYIDILDCNGGDHGYPFATNFNPEINLREVSAPGSYW
                     EDGKWVEVEAMSIKREYDFPQVGQKDMYLLHHEEIESLAKNIPGVKRIRFFMTFGQSY
                     LTHMKCLENVGLLRTDTINFNGQEIVPIQFLKALLPDPASLGPRTVGKTNIGCIFTGV
                     KDGVEKTIYIYNVCDHQECYAEVGSQAISYTTGVPAMIGTKLVMNGTWKQAGVYNLEE
                     LDPDPFMEALNEYGLPWVVVENPQMLD"
     gene            complement(18657..19517)
                     /gene="speE"
                     /locus_tag="VQ540_001416"
     CDS             complement(18657..19517)
                     /gene="speE"
                     /locus_tag="VQ540_001416"
                     /EC_number="2.5.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyamine aminopropyltransferase"
                     /protein_id="HET2545208.1"
                     /translation="MDLWFSEVHTPDVKLSLRTAKQLYAGKSEWQDIEVLDTPAFGKI
                     LILNGHVLFSDADDFVYNEMTVHVPMAVHPNPKKVLVIGGGDGGVAQVLTLYPELEQI
                     DIVEPDEMLVEVCREYFPDFAAGLDDPRVTIYYQNGLRFLRNCEYDYDIIINDATDPF
                     GHTEGLFTKEFYGNSYRALKEDGIMIYQHGSPFFDEDESACRSMHRKVNQAFPISRVY
                     QAHIPTSPAGYWLFGFASKKYHPVKDFDKEGWKKRQLFTEYYTANLHVGAFMLPKYVE
                     DILEEEEGKK"
     gene            19773..19924
                     /locus_tag="VQ540_001417"
                     /pseudo
     CDS             19773..19924
                     /locus_tag="VQ540_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019770457.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         5781 a         4579 c         3545 g         6019 t
ORIGIN      
        1 taattctcaa gctgtgagtt cattatgatt tgtaaatccg atatatcttc agcagctaaa
       61 aacacatttt gaaatgttcc aagtccgttt tcaccaaaac tatattctct cttactatac
      121 ttactcttat tattctctat atagttagag tcaaggttct taacctcttg aagttcattt
      181 tctttacttc tgaggttaaa atcttttact tctgaagtta agttttttga cttctgtaag
      241 tcattttctt ttacctgaaa tatactcata aagtctttaa cataaatgat gttcggctta
      301 ccaagtccaa gccttactct ttcgatcagt cctattcctt tttttacatc aagctcatct
      361 aatgttttta tggcagttgg ctttgagata tttcttcttt tcataatttc ttcgacagta
      421 aaatagataa atactctgcc ttccttgtct atccagttat tcttaaatga cattcctgtc
      481 tgtttaagaa gtatggaata aaggataatt gcttctgctg ataagccccg aaattcttct
      541 ctatcaacta atatctccgg tacttttaag aagttaaatc tttccgcttc tctgttataa
      601 aaatattcaa agtccatgca agatcacctc ccttcttaaa aatttgcaaa gaaaaagacg
      661 atagtttttc ttctatcgcc tttggtaacc atttttatga aattttttaa agttaaaaat
      721 ataatttata atactatctt cttccatttt ctgattttag ttctgaaagt tccaaaaggt
      781 gcaaccgtat ttacatgaat aaacttatac acttcccaag tcgctgtttt agtcgcttca
      841 tcagcccact ttctcatatg cggttcaaat aattcttcct cactcaacga atcaatcatt
      901 gcagagatag aattaatatt ttcatttaat tttgctttca actcttgcag agataaatga
      961 gcgtaggtat ctgtgaacca ctgatataat tcaccaagtt gattccattt aaatttatcc
     1021 gatggtgttt ttacttgaag cccctttctt tcatcttctt cccatttaag aaccaagttg
     1081 gtccaaccaa cctgataagc aaggttttct gctggagttc tgtcaacttc atcagctctc
     1141 ttatctttta aattttctgg aatattatca aattctaaaa tatatttctc aaatgttttc
     1201 tctatctcag cttttagttc ttctttattt tcgtatgttc gcaaaaaatc accttctttc
     1261 tgatttatca atcctttgat ttaaaatgac cttatttttc tatttatacc ttctaagaac
     1321 gctataactg ctgctccaaa catcggtatt ccgtatgggc ttaataaaaa acttaatacc
     1381 aaagcttcta taccaagtga tacatcttta tattatcatc actaattaag ttaaacagaa
     1441 acagacagaa ttattacatc ctgtctccct ttattgtttt tcttcccaat cgtggtaggc
     1501 agcgtagagt tgactcttat tccactggta aatcttagct acttccttaa tagcttgatt
     1561 tttcttcatg ccttgctgga tacgggcttg gatttctaag aacaagtcct cctcgtcttt
     1621 ttcctccaca tcctgactgg caccttcaac aataagaagg cattcgccct tgagtggcgt
     1681 ttcagcgatg ctttccagta attcagaaat tgtacctcgt tggtattctt catagatttt
     1741 ggtcaattcc ctgaccaaaa caaccgagcg gtcaccgtag acttctaaca tattttccaa
     1801 cgtgtctgct acacgatgag gtgattcata aaaaatctgt gtttcaggat aatctttttt
     1861 agagccaaaa aattgcttct gttgacctga ttttctcggt aaaaaaccgt aaaagatatg
     1921 tggctgtggc gctaaaccac tggcaatcaa ggcagaaatt cctgcagagg tacctggaac
     1981 agtcacaact gcaatttctt cctcaatagc tgccttaact aaatcatgac cagggtctga
     2041 aatgctaggc aaaccggcat cagagacctg agcaatactt tgccctgctt tcaagaaacc
     2101 aatcaaatca ggaatttttt ccttggcatt gtgctcatga aaactgatct gcttggtgga
     2161 aatgtcaaaa tgcttgagca aaagccctgt attgcgcgta tcctcagcag caatccagtc
     2221 cacttctttc aaggtctgga tagcacgaaa agtcatatca tctagattgc caatcggcgt
     2281 tgccactaga tacagcttgc catagggaga ctgcccctta aaactttttt gaatttgcat
     2341 gcttactccc tgtataacaa ctcatcacag aacatacatt cttcgtcctg ctctcgacgt
     2401 tgtccataaa aatcattaca tacgtgaaat ccatcacggt aaatacgacg gacactttcg
     2461 cgaacatgct tggccttgac gggagcgtct gcttccacct cacccaagcg ttctcgcaac
     2521 ttactatttt ccaagcgaag agctgtattt tcttctacca agctcttgag atttttcttg
     2581 atggcttcca catcggctaa agttaccaat aattgttggg aaaaatcatc cagcgcgtca
     2641 aataattctt ttttgtccat aaaacagccc tttcctttct ttatcattca tttttgagtt
     2701 tatatttctt tcaagaccag atattccatg gcattttgaa agctgacatt agcttgccac
     2761 atttttctag cttctagtaa atcttgtaga atcactctta ctcttacctg caagaggtcc
     2821 tgcccacaga gaacttcaag aatccgtaaa acctgatcct gtttttcctt atcatctgcc
     2881 aagttggcta atttggcaac ctgtagataa ctttcttttt tcttagctac taaccaagtc
     2941 agcaggcgtt cactttcatc gaccaaggtc caaaaacttg cctgattagc caacttttct
     3001 gcttcagctc gcgattgact aaacttagct aaaagagtcg cttttttctt aacaagtccc
     3061 atttgttcta agagtaagat aagtttttct tcttgctttt taaagtggaa gatctgagtc
     3121 cgacttcgga ttgtcggtaa catcttttcc tcatcgctag tcaagaagaa aatataaact
     3181 tcactctggg gttcttcgat gaccttgagc agagaattgg ctgcgttggg atgcatttta
     3241 tccgcttgct cgatgataaa gacctgttgc tggctttcaa tccctgcttg agaaaactgt
     3301 cccaccaatt cccgaatacg ttctgtcttg atgacctgat tgactggctt aatcaaggtg
     3361 acatctggaa actcttcctg ttcaatcagc ttgcaacttc ggcatttctc acatggtaag
     3421 acgccaactt tatccgtaca aaagaggctc ttagctaaaa attgcgccat ttccaagctt
     3481 ccaaagaaac ctgaaaagag ataggcgtga ttgagctggt cttgttctaa gatacggaca
     3541 aaacggtcaa actgagctgg ttgccaagcc tttagttgat cttgtttcat ttggccaagc
     3601 ccattccgtc aaacaagaca gccttggtag tttccacaac ttgctccaaa gggagactag
     3661 catcaatctt gacaatgcga tttccctctt tatccagaag agaaaggtag ccttgacgaa
     3721 cttttttatg caagtccaac ccttccaaat ccaaacgatt aacctcgcgg tcactattag
     3781 cagcaatacg agccagccct tcttccacct cgatgtcaaa atagagtgtc aaatcgggtt
     3841 tgaggccatc tgtcgcaaac tgattgagcc agtcaatggc ttcaatatct aagccacgac
     3901 caaatccctg ataggcaaca gaactatcga taaaacgatc catgatgacc aacttgccag
     3961 cttcaagggc tggaagaact ttttccacca aatgctgtct gcgactggca atatagagaa
     4021 gtagctctgt tttagcatcc atctgagtat gacttggatc caaaatcact tcccgaatct
     4081 tctccccaat caagactccg ccaggttcac gggtcgtcag cacctttact cctttttcct
     4141 ctaaaattgg tagcagagcc tctaaaacac tggtcttgcc tgctccctct ggtccctcaa
     4201 gagagactaa aaatcctttt gacatgtcta actcatttct tttttactac ttctattcta
     4261 tcaaaaaaat aggggtttgt gacaatcttt ttgtcttctc atttcatact caatgaaaat
     4321 caaagagcaa actaggaagc tagccgcagg ctgtacttga gtacggcaag gtgaagctga
     4381 cgcagtttga atttgatttt cgaagagtat cagccaccat aaaagaggca gataaaacta
     4441 cctcttattt acctagttct tgtgttcgtt tataggcttg atgaactgcc tccatgactg
     4501 tgcctcgaaa agcatgcgct tctaggcttg ctacgccagc aatagtcgaa ccgcctggac
     4561 tacaaacttg atctttcaaa actccaggat gttgctggct ttctaggacc aattgcccag
     4621 ctcctaccac agtttgggct gccattttca aggctgtttc tcgtggtaat cccgtctgaa
     4681 cacctgcatc tgccaaggcc tcaataaaga gatagacaaa ggctggtcca caacctgcaa
     4741 gacctgtcgc tgcattgatt aagctttctc ctaattcaac caagagacca gccttggcta
     4801 aaagctgaca aaagatctca ctgtcctcag ccctgcaatt aggagacaag gcataactaa
     4861 tcactccttg cccgatagaa gcaggggtat taggcatcat acgaataatt cggtgttggc
     4921 ttgggataag acttgctagt ttttctaagg tcaatccagc tgccatcgaa atcaaaagaa
     4981 gactttctct tttttcaagg atggtctggt attgagaaag cagttcagaa aactgagcag
     5041 gcttaacacc tagaaaaatc acatctgctt cttcgaatat ttcttcattg ttagaagtct
     5101 gaccaccgaa gttagcgatg aaagcatcca ccttgacttg actacgattg gcaaggagaa
     5161 tctcatctga cggtctagcc tgcaagacag acttggttaa actagcaccc atattcccca
     5221 aaccgataaa tccaatcttc atctcttact cccttatctg tccatcacca gtgaccacat
     5281 acttgtagct agtcaattcc ttcaagccca taggaccacg cgcgtgcaat ttctgagtag
     5341 aaatccccat ttcacaacca agaccaaatt gtcctccatc tgtgaaacga gttgaggcat
     5401 taacatacac cgctgcagag tccacttgat ctgtaaagta tgctgcagct tcagcatttt
     5461 ccgtcacaat ggcatccgaa tgatgggtac tgtgggattc aatatgcgca accgcttctt
     5521 ctaaactgct cacaacctta acagctagaa tatagtctaa aaactcggta tcaaagtctt
     5581 gtgcttgagc agcttgacct gaaacaaact ggcttgcttt gctatctagg cggaattgaa
     5641 ttggttccaa cccagcttct tttcgatctg caaccaacac ttgctccaag cgaggaagga
     5701 agcttactgc tttgttttca tgaaccagca gaacctccat ggcattacaa acagaaggac
     5761 gactggtttt agcattgttg atgatagaca gcgccttgtc ttcgtctgca tccttatcca
     5821 catagacatg gacaatccca gttcctgtct cgataacagg tacaatcgca ttctcaacca
     5881 ctgcattgat caagccagct cctccacgag gaatgagaag gtctagatag cccttggcct
     5941 tcatcatagc ataactactt tcacggctag tatcctccac cagttgaatc acatttggat
     6001 gaatagtagt cgtctccaag cccttcttca aggctgtgac aatggcatgg gttgtttgat
     6061 aggcatcctt accactacga agaacaaccg catttccact cttaagagtc aaagcagccg
     6121 catcagacgt cacatttgga cggctttcat agataatacc gatgacaccc atagctacac
     6181 gtttttttgt gataaccaaa ccattttcaa gctgacttgt ttctaaaact tcaccgattg
     6241 gatctggtaa ggcaaccact tcacgaattc ctcttgccat cgcttctata cgatctgcat
     6301 ccaaataaag acgatccaac atcacatctg agattttccc cttagccgct gccatatcga
     6361 gggcattagc cgctaaaatt tcctcagtag cagccactaa gtgatcagcc atggctagca
     6421 aggcttggtt tttcacttct tcactagctg tgttaatcga ttttttaaca gcctgtacct
     6481 gttcaaattg ttcttgtcta ctcaccatag tttacctcta aaattctgta aaaagtagtt
     6541 ggatttcagg agtaatggaa atccagtcgt cacggtaaat caagacaccc ttggcttttt
     6601 gaaaacgcaa catatcctcc aaagcagatg ctccaaattg cacgcgtcct tttccaagtg
     6661 attttccact ttccttatca aatactgtca cgatatcacc gtaagaaaag actccttctg
     6721 cttcaacgat accagataag agaagactct ttccatgttg agagagagct tccgcagccc
     6781 ctttatcaac ccaaatagaa ccttgactct gagcatagaa ggcaagccat tgtttctggg
     6841 tacgaagccc cttctcttga gcaacaaagt aagaaccatc ctcggtctcc tctgccgcct
     6901 caaccatgga atctgatttc aaggatgagc agatataaac aggaactcct gattccgtcg
     6961 cgatagttgc agccttgatt ttggttaaca tacccccagt tccgtttgac gaaccagctc
     7021 caccagccat atcaataatc tcacgattga tggtctcgat tctctccaag cgtttggctc
     7081 ttggatctga attaggattt ccagtataga gaccgtccac atctgtcaag aaaactaaaa
     7141 ggtctgcttg gaccatcgcc gctacttgag cacttagagt gtcattgtcc ccaaccttga
     7201 gctcatcaat aacgacacta tcattctcat tgatgatagg aattgcccca cggttgagca
     7261 aaaccgacaa agcctgatgg gcatttttat aacgacgctt atccacaaag tcatcttggg
     7321 tcagcaagat ttgtgcagaa acgatttgac gcaagagaag attggtcgta tattcttcca
     7381 acaaaagtcc ctgccctacc gctgctgaag cctgtttatc agcaatttta gtcggacgct
     7441 ttttaaatcc taaggctcca aaaccagccg caatggcacc tgaagacacc aaaatcaact
     7501 catgaccagc ctcgtgcagc atagccaact gctgggtaat atcctttacc ttactacgtg
     7561 ataaacttcc atcctcattt gtcagagaag aagtgcccac cttaaagaca atccgtttgt
     7621 atttcatagt ctcactccga ttattcatat ttatccatta taacatgaat aacaggaaat
     7681 agaaaagagt tgataggaaa aagaaggccc taaaaccttc ttttctacta ctattctgat
     7741 tccgatttgt ttacactcgt ttcagagctt tgtgaagttg aggatgtcaa atcttgacta
     7801 gttgaagaat ttgtaacact ttcatgttga ctcgtttctt tattttcaag atcctttttc
     7861 actacttctt tggattcttt tatttctgaa tgacttgtag ttttaattgt agcagatttc
     7921 tcgatcggaa catccactaa ccaggcacca cttgaatcca cagtatagcc ttctggtgtc
     7981 ttaccattca caagtaattg accattttct ttcaagaagt accatttatc cttgtcttta
     8041 atccaaccta tagctcgtga accacctgtc ttgtagaaat accaatcatt tgccttttta
     8101 agccagcctt gcttcatagc tcctgattct tctagatagt aatgatgtcc agcaacttct
     8161 atctcacctg tcttcatgat accagtagaa tccatatagt accaggcttc tttatctttt
     8221 acccagcccg ttttcatttc ccctgatgga gcaaagtaat accattgccc cttatattga
     8281 agccaacctg tcttcataga gccatcaaca tccaaataat accactgctc tttatcttga
     8341 acccaaccaa tttccatctg attttctttg ttaaaataat accagattcc atcaattttc
     8401 ttccaatttt tagcagaagc accagagtct gtcaaataga accaatgatt gttccatttt
     8461 ttccattgat tctgtaacaa gatacccgtt tggttaaagt aataccattc accttcgatt
     8521 tcattccaac cgacagcata ctctcctgta gaatcaggcg cttgatacca ccagttccca
     8581 tatgcactct tatgccaacc agcttgaaaa cttggaatcg gcttgtagga tgttgaaata
     8641 ttgacaaaac cgtcttttcg aatatcaaaa actgttgcat catagtcttt gctggctgcg
     8701 ttgattctct caattcctcg ttctttgagc caattaacat actcactatc aacaccattt
     8761 ttccaaggta gactatccga agtttgaaca atcaaactcg gactcaaatt tttaatgaaa
     8821 tccttggtat ttgatttgtt ggtatcatgg tgatgattaa acttcatcaa atcaactttt
     8881 ccaatgagag gaccatactt gtcttctgct ccatgaacat tatctaaatc gcccccaagg
     8941 taaattttct tgccattgac tttcaccacg ctaatcaagg aattggaatt gtcatcccaa
     9001 attttcttta attcacccga tgaatcagtt tcattttcat aattatagag ctgaatatcc
     9061 atgtccccaa actgaaaatg agcatcccct tgtgtgatat tttgaataac tgaaacacct
     9121 ttttctgcag cagtctgtaa aaccttatca tagccataca gattatccca tagacgttca
     9181 gaattagtaa tacgactatc actatatttc ttaagataga ctcggtcaac tggataggta
     9241 gacagtaatt catcaacatt tccaatatga tcactgtggg tatgggtcac caaaataaaa
     9301 tcaagttttt ggacacccaa ttccttcaaa cgacgaaaga cacggtctgt tagaacatgc
     9361 ttataagacg tttcaattcc ttctctccat ggataacgag aatcacttcc atctgggaaa
     9421 tcataatctt ctcctgtatc caccatggca aaatgtccat tgctttcaag aataatcgca
     9481 tcactgccac cttcttgaac attgataaag tggattttat ttcctgaact ttcttgagcc
     9541 tgaacattcc cataccatga caaacctaaa aaagcgccta caagtgctaa actagttaat
     9601 ttctttttca ttcttacttt ctcaatctct ccaaggtttc cttaaaaatc tctgggatat
     9661 ctgctttaaa ttccaaggtc ttacctgttc tcggatgagt aaaacctaaa gtcttggcat
     9721 gaagaaattg tccatgtcct ttcaaagtct tgcgaggacc atagacctca tcaccagcga
     9781 ctggatggcc gatataagcc atgtggacac ggatttgatg agtgcgccct gtctccagtt
     9841 gcaactctac taagctataa tcgccaaagc gttccaagac gtgaaaacgc gtcactgcag
     9901 gcttcccttt agcagttaca gcctgtttct tacggtcttt ttcactccgg ccaatcggcg
     9961 cttcaattac accacgatca ttaggcagat ttccatgaac aatcgcccaa tatttgcgga
    10021 gagacttttt atctttgagt tcttgggcaa gtactagatg cgcatcatcg tttttagcaa
    10081 tcatgagaag acctgacgta tccttatcaa tacggtgaac aatccctgga cgcagaaccc
    10141 cattgatacc cgacaagtcc ttaatatgat acatgagggc atttactagg gttccactgg
    10201 tatgaccagc actcgggtgc acaaccattc cctgaggttt gttaacgaca gccacatcct
    10261 catcttggta gactatttct agcggaagat cctcagccac atactctaat acctctggtt
    10321 ctggcacatg gtaagtgacg acatcaccct cttggactgt gtatttagct ttcttgactt
    10381 gaccattgac caagacctgg cctgatttaa tttgttcatt cgcgagacta cgtgataatt
    10441 ctgacaaatc tgacaaagcc ttatccaaac gcagaccacc agtttcaatt ttaatttcca
    10501 tttatttcct cttttagcat tgcaatcaat aaaataatca ctccaaccgt cagatagcta
    10561 tctgccacat tgaaaattgc aaagttgata aagtcaaggt ggaacatatc cacaacaaag
    10621 ccctgactga ccctgtcaat aaagtttcca agaccacccg cgattattag agtcaaaccc
    10681 aagaacatcc agaatgagtc ctccatgtgt ttatgtaaat accaaatggc acctatcacg
    10741 acaaccagag taatgacagc gaataacagc tgctgatctt gtaagataga aaaggctgca
    10801 cctcgatttt gcaggtaggt caagctaacg aaattgggaa tccaggagcg cacttcaccc
    10861 agtggaatct gctggacgat ataggatttg accaactgat ccagcccaat taaaagcagt
    10921 acaatgactg ccactattgc tctttttttc atgatttcct cttttgatca aaatattctt
    10981 gcatgacttc tacgaagaga gtcccagctt gactaagctc cacttcttca cgtttaacat
    11041 agaccatgcg gttatctagg ttatccttga gacgaataac tgtaatgcca ttaacactgt
    11101 cactatctaa aaatccagaa cctgtcgcat aggcgtccgt ccgctccaaa ataccattca
    11161 aggtggcacg gtctgtcaca ttaaacatct gtgagctagc gctggtatcg acaaagttct
    11221 ctgaataata aaggtactcg tctttctctt gagtgaaacg aaccgttggt aaatccgcta
    11281 aatcctccat gactaattcc tctttctggg ctaaaggatg accctcacag agataaatat
    11341 gggtatggaa aggaatcaat tcgatgacct ccagacctaa cttttcaacc cgttgcataa
    11401 tccccttttt attttgattg ttgaggtaga taatcccaat ctcactatgc ccttgcgcca
    11461 cttcatctaa tatttgaaca gtagttgatt caaaaatacg gaagttctta tagtcaggat
    11521 agcgctctga aaaggccgta atagttggtg gtaagaagtc atagtgctgg ctagcaacgg
    11581 aaaattcatc tttttcttct tcaggattgg catactgatt ttgaaaaata tcaaatcctt
    11641 taaccaattc ttgcgctttt tcataaaatt ccatcccacg acgggtcaag aaagtccctg
    11701 agctggtccg acggaaaatc ttaaagccca actctttttc caaatcacga acagaaatag
    11761 acagactcgg ctgactaaca tacatctttt cagcagcttc acgaaaagta ccactattgg
    11821 caatagccac aacatagcgt aattgttgaa tgttcatctt ctacccccaa cttctttatc
    11881 ttttcattat accatatttt agaagttttc caaaaaggaa aaaagaacat cctattcttc
    11941 ttaactatct tcactatctg cctttctcac gccaatctta ttttcaaaat caattcaaaa
    12001 aaataagtgg ctacacacca cttcagtatc ggaaagaaaa acgttgacta tttgtgaaaa
    12061 aagaaaatgc cggaaaattc cgacattttt ttagtaagct aacttcctga aaataggagt
    12121 aaccaaacat cccagaaggc agtgatattg atgagaatat gaactagtat tggatagtag
    12181 agatttttag tcatgcgata caatagagct aaaatcagac ctccactagc ataaatgaaa
    12241 aaagcaagag gagttaaagc aaaattgata tgaatataac cgaaaataat agcagaaagc
    12301 aaaacatctc cgtaccaagg tgagtttttg aaaaaggttg tcataagcac acctcgataa
    12361 atcaattcct cagcaatagg ggcgatgaag caaacgatga gcaagaaata agggaactcc
    12421 tgtctcccca tcatttctac cgtttcattc aaagaaatct gatttgaaga cagggatatg
    12481 aaatacgaaa agaggaagtc agacatatat gaaatgatgt agcccagtaa aaggtagatg
    12541 aagtacctca gctgccactt gaaatgaaaa attttctttc ctgcaaaaac cagtagatag
    12601 atgaccgcta agaaaagaac tccgctctcc atcaaaagca gaatctgaaa aaattcacga
    12661 cttgctggta gatagggctt tgcgaggtga ttgaaaactc tccaaaacca agttgatttg
    12721 taaaaaatta aggacaatgc tagtaaaatt tgaatagccc gttttttcat attaaattct
    12781 ctgctttctc cacttatttc ttcatattac taataaattt tacttaaaat ctcgcagcac
    12841 ttcctttgca aagatgattg cctcctccaa tatatcctaa atcataggtg cctctgggac
    12901 aaaatccatg aaccggcaga gttaatactg gttctatttc ccaatcgtac ctaccattag
    12961 gatttttacc atatgaatct gctccacctt gtatcagctc taattcttca tttgttagat
    13021 ttatattttt tgtcattaaa atcatgatat atttcctcca ttattcttca gattagttga
    13081 gtaatctgat actcatacct acttacaaaa aaactattat attaagttgg ttttttaatt
    13141 tgtctagttg caacattgac aaacatagta tagcatatct ttgcgaaata tcctcttcaa
    13201 atcatgaatt gtcatcaaaa catcttaaac tataaaatca attagtctca agctttctat
    13261 caatttcttc tccaaaatat gctataataa tagcaaaaga taaagaagga agacctatga
    13321 ttaaactact agccttggat atggacggca ccctcctcaa tgaagccaag gaaatcccac
    13381 aagctcacat tactgctatt cacaaagcca ttgaaaaagg tgtcaaactg gttctctgta
    13441 cgggtcgccc ccttttcggt gtcctcccct actacaaaaa actgggactc gacctccaga
    13501 atgagtatgt gattgttaac aacggttgtt caactcacca gactagcgac tggggcttgg
    13561 ttgactggca agaacttagt ccagctgaca tcgaatacct ctatgacctt gctgaaaaga
    13621 gtgatgttca gttgacactt tttgacgagt cacattattt tgttctcggt ggaaagccca
    13681 atcaagttat tgaaaatgat gctaaactag tattttcaga cctgactgaa atttctcttg
    13741 aggaagcgac tagtggaaag ttccggatgt tccaaggtat gtttttagga acaaaagaac
    13801 aaacagacga ttttgagcag cgttttgctg aagagctttg ccaacgattc agtggagttc
    13861 gttcgcagcc tgtcatttat gaagcaatgc cacttggaac gacaaaggct actgctcttt
    13921 cacgactagc tgagattttg aagattgatt cctcagagat tatggccatg ggcgatgcta
    13981 ataacgatat cgaaatgctc cagtttgcag ggcttgggat tgcaatggga aatgccagcg
    14041 attatgtcaa atctcttgcg gatgccgtta cctcaagcaa cgaagaagac ggcgttgcgc
    14101 gtgctattga gaaatatatt ctataaaaaa gaaaagcaaa tagacagaag ttactgctat
    14161 ttgctttttt gctaatattt taaaatacgg actaatcaat agagaagaat agcgaatcat
    14221 aaaaatcgat ttactagatg ccatagtatc ttatagttgc taataagaag ttagtctagc
    14281 agaatgaatc tctcatttct cccacactaa tctgtaattt gtctatacat ttctggtctt
    14341 ctatctcgaa acaagcccca gtttaggcgt tcacttgctc ccttgtctag gttataagta
    14401 gctaacagaa cagcttcttc ttgtctttca gctcgttcta gaatagctcc tgtttcatcc
    14461 gtcataaagg aggaaccgta gaagtcaaga ctggaactct gtccgccatt ttcctcacta
    14521 ggagtaacct cctctaaacc ataacgattg gctgcgatga ctggaacaat attcgctgct
    14581 gcgtgccctt gcatagtacg ttgccagtga ccacaactat ctgtatccaa aattggctct
    14641 gaaccgatag ctgtaggata aaagagcaat tcagcaccat tcaatgcaag acagcgcgct
    14701 gtttcaggga accattgatc ccaacagata ccgataccaa tcttagcata gcgagtattc
    14761 cagaccttga aaccagtgtt accaggcgtg aaatagaatt tttcttgata ataatggtca
    14821 tctggtatat gggtctttcg ataaacgccc agcacttccc catctgcatc aatgacggca
    14881 atagagttat acaagacatt accatctttt tcatagaaac tgattggtaa aacaacttgt
    14941 agttccttag caagcaactt aaaatgctga atggcagtat tttccgctac agattgggca
    15001 tactggtagt agtcatactg acgttcctga cagaaatagg gatgttcaaa caactcgggc
    15061 aagagaataa tttgggctcc ttgctcagca gcctgacgta ctaaacgctc tgcggtttgg
    15121 atatttgttg ccacatcctt agcgcattgc atctgaatgg ttgcaactct tacatttctc
    15181 atctttttct cctattctgg aatttgttgg gtgatacagt ggatattgcc accacctaag
    15241 agaatatctc tggctggtat tccgacaact ttacggtctg ggaaacactt gctgaggata
    15301 tctaaggcca cttggtcgtt tacatcctca aactgtggaa ccaagacagc cttgttggcg
    15361 atataaaagt ttacgtagga agctgctagt cgttcacctg cgtatcgctc ttcttctcct
    15421 tcttcataga tgtagcctgg caaatcttct tctgtcacaa cttgtcgaac tgcagggata
    15481 ggcaatttat gaatggtgaa gtgacaacct tttgcatctg tttcctgttc taagagttcg
    15541 agatctgctt ttgacatggc atactgggga tcattttcgt catctgtcca agccaaaaca
    15601 acctcagcag gaccaacaaa ggcaacaaca ttatcgacgt gttcattggt ttcatcctga
    15661 taaataccat aaggaagcca aataactttt tcagcaccaa gactttctaa taatgtgttt
    15721 tcaatctcct ctttagtcaa gttaggattg cgaccaggac taagcaagca actttcagtt
    15781 acgagaatag ttccttgacc atcgctatgg attgcgcctc cttccagtac aaaaggttta
    15841 gcatcataga caggcctttc caaggcctca gcaaaacgac tggctacttg gtcatcctct
    15901 tcataatctt gataaagacc atcataggtg cctccccaag cattaaaggc ccaatccacg
    15961 gctaatttct tacctttatc attgacgaga atggttgggc cagtatcacg cgcccaggca
    16021 tcattggtgg gaatgtctaa ataaacaacc ttgtctccaa gataggattg ggcttcagat
    16081 agataggcct gctccaccaa aagatagact ctttcccctt ctgctatggt ctcgatgatc
    16141 tgagtaaatg ctcttttagc agcctttcct tgaaaaggcc atgatcctgg tcgagtcggc
    16201 catatcatga gggtaccatg atggggttcg tactctgctg gcatgtgata gcctaatttt
    16261 tttggactgt ccatcatgat aatctccctt taaagtcttg atagccaaaa gctttgagta
    16321 agctacagtc tccctgttcg tccatgagat agagacttgg caatccaata ccattaaagg
    16381 tattattttt gacaaaagaa taaatggcca tgtcttgaaa ataaagtctg tctccgattt
    16441 ggactggatt ttcaaaacta taatcaccaa tcacatcgcc agtcagacag gtattagaag
    16501 aaagtctgta ggtatgggct ttttcctgtg actcaaagcc atttctcaaa ggtggacgat
    16561 agggcatctc aagtacatca ggcatatggc aggtcgcaga ggcgtctaaa accaagattt
    16621 ccataccgtt ttctacaata tctaatacct cagttgctaa ataacccgca ttaagcgcaa
    16681 tggcttcacc aggctcgata tagatttcaa gattgtaagt ttttcggata cgcttgattt
    16741 ctgaaatcag caaatccaca tcgtaacctt ctcttgtaat atgatgacca ccacccatat
    16801 tgagccattt tacctcatgt aagtagggac caaactgttc ttctactgct ttcaaagttg
    16861 tttgtaaatc atctgctccc tgctcgcaaa gggtatgaaa atgaagtccg tcaaccaaat
    16921 ctagcaaatc gctcggaatc ttgtctatag taactccaaa gcgagaacca ggtgcacaag
    16981 ggtcatagag cgcgtgatct ccttgagttg aacactgagg gttgaggcgc aaaccaacac
    17041 tgacaccagc ctctcgacaa cgagccccat gcttacgcaa ctgtctctct gagttaaaga
    17101 cgatatggtc tgttatccca agcaattcct ccatgtcctc atccttgaaa gctggtgcaa
    17161 aaacatggac ttcaccagga aattcttccc ttgccaattt ggcctcatag agtccactag
    17221 ctgtcgtacc tgatagatac tggctaatca agggataagt tttgtagagg gaatatgcct
    17281 tctgggcaag caagaccttg caaccggcct cttcttgtac atattgtaga atgcggcaat
    17341 tagcttctaa cttggccaag tcaataacat aggctggtgt tggtacttgt tctaacttca
    17401 ttagtccaac atttgtggat tttcaaccac aacccatggc aaaccatact cattcaaagc
    17461 ttccatgaat ggatctggat ctaactcctc aaggttatac actccagctt gtttccaagt
    17521 tccgttcatg actaattttg tcccaatcat ggctggaacg cctgtcgtgt atgaaattgc
    17581 ttgtgacccg acttctgcat agcactcttg atggtcgcaa acattgtaga tgtagatagt
    17641 cttttcaacg ccatctttga cacctgtaaa gatacatcca atattggttt tacctacagt
    17701 acgtggacca aggctagcag gatctggaag caaggctttc aaaaattgaa ttggaacaat
    17761 ttcttggccg ttaaagttaa tggtatccgt acgaaggagt ccaacatttt caagacattt
    17821 catgtgcgtc aagtaagatt gaccaaaagt cataaagaaa cgaatgcgtt tgacacctgg
    17881 aatgttcttg gccaatgatt cgatttcttc atggtgaagg agatacatat ctttttgtcc
    17941 aacttgaggg aaatcatact cacgcttgat agacatagct tcgacttcga cccatttccc
    18001 atcttcccag taagaacctg gcgcagaaac ctcacggaga ttaatttctg gattaaagtt
    18061 ggttgcaaat ggataaccgt ggtcaccgcc attacagtct aaaatgtcga tataatggat
    18121 ttcatcaaaa tagtgtttga gggcataagc tgaaaagaca ctagttacac ctgggtcaaa
    18181 accagaacca agaagagcag tcaagcctgc ttctttgaat ttctcttgat aagcccactg
    18241 ccatgagtag tcaaagtagg ctgtaaaacc aagttcctta caacgttttt cgtagatagc
    18301 acgccactca gggtcttctg tgtcttctgc ttcgtagttg gctgtatcga tatagtgaac
    18361 acctgttgcc aaacaagcat ccataatggt taaatcttga taaggcagag ctacattcaa
    18421 aacagcttct ggtttgtagc tttcaatcag agcaatcact tcttcaacct tgtcagcatc
    18481 aagagcagct gtctcaatct ttgtacttgt tttgccttcc agtttagctt tcaagtcatc
    18541 gcattttgac ttggtacggc tagcaatcat aatctctgta aatgtttcgc tatcttgaca
    18601 aatctttgaa atagcaactt gggcaacgcc cccacaacca ataactagta aacgactcat
    18661 ttttttcctt cctcttcttc taaaatgtcc tcaacatact tgggcaacat aaaggctccc
    18721 acgtgtaagt ttgcagtgta gtattctgtg aaaagctggc gttttttcca gccttccttg
    18781 tcaaaatctt tgacagggtg gtattttttc gatgcaaatc caaacaacca atagccagct
    18841 gggctagttg gaatatgggc ctgataaacc cgactgattg gaaaggcttg attgaccttg
    18901 cggtgcatgc ttcggcaggc cgactcatcc tcgtcaaaga acggactccc atgctggtaa
    18961 atcatgatgc cgtcttcctt cagagctcga taactattgc cgtagaattc cttggtaaag
    19021 agtccttccg tatggccaaa tggatctgtc gcatcgttga tgataatatc atagtcatat
    19081 tcgcagtttc gcaaaaagcg tagcccattt tggtagtaaa tggtaacacg aggatcatct
    19141 aggcctgcag caaagtctgg gaaatactca cgacagacct cgaccaacat ctcatccggt
    19201 tccacgatat cgatttgttc cagttcagga tagagtgtta atacttgggc aacaccgccg
    19261 tcaccacccc caataaccaa tactttcttt ggatttgggt ggacagccat gggaacgtga
    19321 acggtcattt cattgtagac gaaatcatcc gcatctgaga acaagacatg gccatttaaa
    19381 atcagtattt tcccaaaagc tggcgtatcc aagacttcga tatcctgcca ttcacttttt
    19441 ccagcgtaaa gttgcttggc tgttctcaga gacaatttga catctggagt atgaacttca
    19501 gaaaaccata aatccatcta tttctcctta tattatattt agcgcagtta gctactgcca
    19561 aagcccaagt ggtatacttg gaataagcca ctgtggatta gttcatttcc tccaatcgct
    19621 tgacgatttc cgaaagggtc taaccacagc tttttgtttc aattggtaat gagtttgata
    19681 acgcatagac gttttatctc gtctaaggta acaaggcaaa aagttcgtgg ataaccaagt
    19741 agacttgaaa tactatatct ggaggtactc ccatgcttta tgtgggcatt gatgtcgcta
    19801 aaaataaaca cgatgttaca gccttgaatg ttcgaggaaa actgttctta aaccactcac
    19861 tttttcaaat aataaagctg gttttgaact cttagatctg tctcttcgac aactcaacca
    19921 agac
//
LOCUS       DAVBDR010000039        19487 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.039, whole genome shotgun sequence.
ACCESSION   DAVBDR010000039 DAVBDR010000000
VERSION     DAVBDR010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 19487)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19487)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19487
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.039"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            <1..4786
                     /locus_tag="VQ540_001418"
     CDS             <1..4786
                     /locus_tag="VQ540_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HET2545209.1"
                     /translation="QGERGLTGAKGEKGDQGERGLTGAQGEKGDRGERGLTGAKGEKG
                     AQGQAGRDGVTPTVTVKDNKNDGTHTITINDGRGNVTSTVVRDGFDGASPLVATQRND
                     ADKTTTVIFYYDKNGNNELDASDKKLKEVVIADGAKGEKGDKGEQGLQGRDGEQGPKG
                     EDGKTPTVKVTDGQDGTHTITINDGKGGITTTVVRDGFDGASPLVSTHRNEADKTTTV
                     IFYYDLNDNNQFDEGDTKLKEVVIADGKQGPKGDKGDNGKDGFTPEVTVTDNNNGTHT
                     ITITQPDNRPSLTTIVKNGEDGKTPKVKAERDDAKKQTTLTFYIDKDGDGSYTAGKDE
                     LVQTTVVKDGQDGAAGASGRDGKEVLNGKVDPTTEGKDGDTFVNTQTGDVFVKKGNTW
                     EPAGNIKGPKGDKGADGAKGEKGAQGERGLTGAQGVKGEKGDQGERGLTGSKGEKGDQ
                     GERGLTGAQGAKGDKGEQGLQGRDGAQGPKGADGQRGPAGPQGPKGEQGNPGTPGKDG
                     KSLIAVKNGTETKVYVEDPARPGQPLNPNQPLATITDGRNGTNGQSPTITATRSVQNG
                     KNGVLVTITPVGGRPQTTFVEDGQKGADGKTPTVTITEGQNGTHTLTVHNPGSPDVTT
                     TIRDGATGQAGRDGKDVLNGKVNPQPNQGKNGDKYINTETGDVYVKNNGNWDKEGNIK
                     GPKGDKGADGAKGEKGDQGERGLTGAQGAKGADGAVGRDGRDGKDVLNGKANPEAHQG
                     KDGDKYVNTETGDVFVKNNGNWDKEGNIKGPKGDKGERGEDGKTPEVTVTPGKDGHST
                     DITFTVPGKDPVTVNVKDGENGLNGKTPKVDLLRVQGKNGNPSHTIVTFYTDENNDGK
                     YTPGTDELLGSEMIKDGAKGADGRDGKSLLTVKDGKETKVYQEDPANPGQPLNPEKPL
                     AVIRDGVDGKSPTVTAVRKDEAGHKGVEITVDNHDGSQPTTVFVQDGAKGETGATGQD
                     GQTPTITTQRGQDGQSTVVTITTSGKDPVTFTVKDGKNGKDGRAPKIKVEDITSPSRI
                     RRDTDAAATPTRNGIRVTVYDDVNDNGVYDEGVDKVLNSKDIYNGIDGRDGSAPTITT
                     KDNGDGTHTITVQNPDGSESTTVVKDGKDGKTANITTTENPDGSHTITVTNPDGSTKE
                     TVVKNGKDGKTPKVEVTDNNDGTHTVKVTDGDGNVTNAIIKDGKDGKAATATTTENPD
                     GSHTVTITNPDGTKNEFVVKNGRDGVDGRTPTASVRDNGDGSHTIVITNPEGVTTETT
                     VRDGKSPKVTITDEQNGTHKISVLNGDGTTTTTTVRDGREPKLEVIDNNDGSHTIKVT
                     GADGKGTTTTIFDGKSPKANIVDNGDGTHTLTIVDSDGREYKSIIKDGKDGKDSVSPT
                     VTVKNNNDGTHVVTITNPDGSKTEMVIKDGKDGKSPKVSVEDNGDGSHTITIINSDGT
                     VTKTVIKDGRDGRDGRDGKDGKDGKDGKCGCQDKPVTPSNDKPVPPTPNVPTPEVPVK
                     PVPAQPTPNVPTPEVPVQPTPAVPTPEVPVKPVPAVPEQPVVPTPAQPATPVNANPVA
                     PTTGKENRGDKLPETGSQSDYISVLLGSGILLSLYVGRRKEA"
     gene            complement(5023..5571)
                     /locus_tag="VQ540_001419"
     CDS             complement(5023..5571)
                     /locus_tag="VQ540_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HET2545210.1"
                     /translation="MSKKVLFIVGSLRQGSFNHQMALEAEKALAGKAEVSYLDYSALP
                     LFSQDLEVPTHPAVAAAREAVLVADAIWIFSPVYNFSIPGTVKNLLDWLSRALDLSDT
                     RGVSALQDKFVTVSSVANAGHDQLFAIYKDLLPFIRTQGVGDFTAARVNDSAWADGKL
                     VLEETVLNSLEKQAQDLVEAIQ"
     gene            5892..6380
                     /locus_tag="VQ540_001420"
     CDS             5892..6380
                     /locus_tag="VQ540_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HET2545211.1"
                     /translation="MKKRQNKAKNNLLWQYGLGMTILFVVISASFLYMVSLSMKPYQT
                     AKSEGEKLAQQYAGLEQADQVDLYNGLESYYSVLGRNKQQEALAVLIGKDDHKIYVYQ
                     LNQGVSQEKAETVSKEKGAGEIDKIIFGRYQDKPIWEVKSGSDFYLVDFETGALVNKE
                     GL"
     gene            6377..7564
                     /locus_tag="VQ540_001421"
     CDS             6377..7564
                     /locus_tag="VQ540_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HET2545212.1"
                     /translation="MKLSNRVLEMEESVTLAAGARAKALKAEGRDILSLTLGEPDFTT
                     PKNIQDAAIASIRDGRASFYTVTSGLPELKAAVNSYFERFYGYSVASNQVTVAAGAKY
                     SLYTFFMAVVNPGDEVIIPTPYWVSYGDQVKMAEGVPVFVSAKEDNHFKVTVEQLEAA
                     RTDKTKVLVLNSPSNPTGMIYTREELLAIGNWAVENDILILADDIYGRLVYNGHEFTP
                     ISSLSEAIRKQTVVINGVSKTYAMTGWRIGYAVGEADIIAAMSKIAGQTTSNPSAVAQ
                     YAAVEALSGEQDTVESMRQAFEERLNTIYPLLAEVPGFEVVKPQGAFYLFPNVKKAME
                     MKGYTDVTDFTTVILEEAEVALVTGAGFGAPENVRLSYATDLDTLKEAVERLKAFMGS
                     END"
     gene            7557..7922
                     /locus_tag="VQ540_001422"
     CDS             7557..7922
                     /locus_tag="VQ540_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HET2545213.1"
                     /translation="MIDHFEIKVKDLQISEGFYRSFLAPLDYKLAFKTSSLISFLSPN
                     SPHPGGDFWLTQGTQDPVHFAFLAENKEEVQACYEAGLEAGGRDNGAPGYRSEHPIYY
                     AAFMIDLDGNNIEVVCHKE"
     gene            7938..9284
                     /gene="asnS"
                     /locus_tag="VQ540_001423"
     CDS             7938..9284
                     /gene="asnS"
                     /locus_tag="VQ540_001423"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HET2545214.1"
                     /translation="MMTKRVTIIDVKDYVGQEVTIGAWVANKSGKGKIAFLQLRDGTA
                     FFQGVAFKPNFVEKFGEEVGLEKFDVIKRLSQETSVYVTGIVKEDERSKFGYELDITD
                     IEVIGESQDYPITPKEHGTDFLMDNRHLWLRSRKQVAVLQIRNAIIYATYEFFDKNGF
                     MKFDSPILSGNAAEDSTELFETDYFGTPAYLSQSGQLYLEAGAMALGRVFDFGPVFRA
                     EKSKTRRHLTEFWMMDAEYSYLTHDESLDLQEAYVKALLQGVLDRAPQALETLERDTE
                     LLKRYIAEPFKRITYDQAIDLLQEHENDEDADYEHLEHGDDFGSPHETWISNHFGVPT
                     FVMNYPAAIKAFYMKPVPGNPERVLCADLLAPEGYGEIIGGSMREEDYDALVAKMDEL
                     GMDRTEYEFYLDLRKYGTVPHGGFGIGIERMVTFAAGTKHIREAIPFPRMLHRIKP"
     gene            9437..9727
                     /locus_tag="VQ540_001424"
     CDS             9437..9727
                     /locus_tag="VQ540_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018030687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HET2545215.1"
                     /translation="MAKYEILYIIRPNIEEEAKNALVARFDSILTDNGATVVESKTWE
                     KRRLAYEIQDFREGLYHIVNVEANDDAALKEFDRLSKINADILRHMIVKIDA"
     gene            9739..10209
                     /gene="ssbA"
                     /locus_tag="VQ540_001425"
     CDS             9739..10209
                     /gene="ssbA"
                     /locus_tag="VQ540_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein SsbA"
                     /protein_id="HET2545216.1"
                     /translation="MINNVVLVGRMTRDAELRYTPSNVAVATFTLAVNRTFKSQNGER
                     EADFINVVMWRQQAENLANWAKKGSLIGVTGRIQTRSYDNQQGQRVYVTEVVAENFQM
                     LESRSVREGHTGGAYSAPTANYSAPTNSVPDFSRNENPFGATNPLDISDDDLPF"
     gene            10241..10480
                     /locus_tag="VQ540_001426"
     CDS             10241..10480
                     /locus_tag="VQ540_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HET2545217.1"
                     /translation="MAQQRRGGFKRRKKVDYIAANKIEYVDYKDTELLSRFVSERGKI
                     LPRRVTGTSAKNQRKVTTAIKRARVMALMPFVNED"
     gene            10775..12175
                     /locus_tag="VQ540_001427"
     CDS             10775..12175
                     /locus_tag="VQ540_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional Cof-type HAD-IIB family
                     hydrolase/peptidylprolyl isomerase"
                     /protein_id="HET2545218.1"
                     /translation="MDAKLRYKAKKIKIVFFDIDDTLRNSKTGFIPTTIPTVFKQLRE
                     KGILTGIASGRGIFGVVPEIRDLKPDFFVTLNGAYIEDKKGQVIYQHQIEKSYVEEYI
                     SWAKQEGIEYGLVGSHDAKLSTRTDMMSEAINPIYPDLDVDPDFHEKEDIYQMWTFED
                     KGDDLHLPDSLSDKLRMVRWHQHSSDIVPISGSKATGVEKVVEHLGLKPEKVMVFGDG
                     LNDLELFDYAGISVAMGISHDKIKEKADYITKTLEEDGIFDALEVFGMVEKELHFPQV
                     DIETVEGPLATIKTNHGDLRIKLFPEHAPKTVANFVSLSKDGYYDGVIFHRIIKDFMI
                     QGGDPTGTGMGGESIYGESFEDEFSEELYNIRGALSMANAGPNTNGSQFFIVQNQHLP
                     YSKKEITRGGWPEPIAEIYANQGGTPHLDRRHTVFGQLADEASYAVLDVIAAVETGAM
                     DKPVEDVVIETIEIED"
     gene            12177..12536
                     /locus_tag="VQ540_001428"
     CDS             12177..12536
                     /locus_tag="VQ540_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HET2545219.1"
                     /translation="MKIGDKLKGRITGIQPYGAFVELETGDTGLIHISEIRTGFIENI
                     HETLKVDEEVQVQVVDLDEFTGKASLSIRTLEEEKYQFPRRRRFSSDRFNYGFAPFRR
                     MLPIWTGEALHHLKKKK"
     gene            12590..13339
                     /locus_tag="VQ540_001429"
     CDS             12590..13339
                     /locus_tag="VQ540_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HET2545220.1"
                     /translation="MEEEQLLKSGERINQLFSTDIKIIQNREVFSYSVDSVLLSRFPR
                     FPKKGLIVDFCAGNGAVGLFASTRTQAQILSVEIQERLADMAERSVRLNGLEEQMQVI
                     CDDLKNMPAHIQGSKVDMILCNPPYFKVDPYSNLNESEHYLLARHEITTNLEEICHSA
                     QSILKSNGRLAMVHRPDRLLDILDTLKRHNLAPKRLQFVYPKREKEANMLLIEAIKDG
                     STSGFKVLPPLIVHNDDGSYTPEIEEIYYGS"
     gene            13329..13628
                     /locus_tag="VQ540_001430"
     CDS             13329..13628
                     /locus_tag="VQ540_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HET2545221.1"
                     /translation="MDHKAYMYVLECRDGSYYIGYTTDMRRRLAIHNSGKGAKYTRAR
                     LPVKLIYAQGFASKEEAMSAEALFKRKKRPQKEEFLSENQDRNLLSYFEESWGVL"
     gene            13699..14634
                     /locus_tag="VQ540_001431"
     CDS             13699..14634
                     /locus_tag="VQ540_001431"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HET2545222.1"
                     /translation="MSKILVFGHQNPDSDAIGSSVAFAYLAKEAYGLDTEAVALGTPN
                     EETAFVLNYFGVEAPRVITSAKAEGAEQVILTDHNEFQQSVSDIAEVEVYGVVDHHRV
                     ANFETASPLYMRLEPVGSASSIVYRMFKEHGVAVPKEIAGLMLSGLISDTLLLKSPTT
                     HPTDKIIAPELAELAGVNLEEYGLAMLKAGTNLASKSAEELIDIDAKTFELNGNNVRV
                     AQVNTVDIAEVLERQAEIEAAMQAANESNGYSDFVLMITDIVNSNSEILALGANMDKV
                     EAAFNFKLENNHAFLAGAVSRKKQVVPQLTESFNA"
     gene            14721..15233
                     /locus_tag="VQ540_001432"
     CDS             14721..15233
                     /locus_tag="VQ540_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000892254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoylalanyl-D-glutamate--2,
                     6-diaminopimelate ligase"
                     /protein_id="HET2545223.1"
                     /translation="MLENGDLIFVRDGSDMGQAIQTSTGNYSHVAIYLDGMIYHASGQ
                     AGAVCQEPADFFESNHLYDLYVYPEMDIQSVKERACRHLGAPYNASFYPDAAGFYCSQ
                     YIAEILPIFETIPMKFGDGEQEISDFWREYYIELGLPVPLNQAGTNPSQLAASPLLQC
                     KERNLHDSDF"
     gene            15270..15865
                     /locus_tag="VQ540_001433"
                     /pseudo
     CDS             15270..15865
                     /locus_tag="VQ540_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809149.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
     gene            15966..16160
                     /locus_tag="VQ540_001434"
     CDS             15966..16160
                     /locus_tag="VQ540_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HET2545224.1"
                     /translation="MSLENKLEQATGAVKEGFGKVTGDSKTELEGAVEKTVAKAKDVV
                     EDAKGAVEGAVEGLKNVFTK"
     gene            complement(16206..17651)
                     /locus_tag="VQ540_001435"
     CDS             complement(16206..17651)
                     /locus_tag="VQ540_001435"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HET2545225.1"
                     /translation="MIKIETVLDILKKDGLFREIIDQGHYHYNYSKVIFDSISYDSRK
                     VTEDTLFFAKGAAFKKEYLLSAITQGLAWYVAEKDYEVDIPVIIVNDIKKAMSLIAME
                     FYGNPQEKLKLLAFTGTKGKTTATYFAYNILSQGHRPAMLSTMNTTLDGETFFKSALT
                     TPESIDLFDMMNQAVQNDRTHLIMEVSSQAYLVHRVYGLTFDVGVFLNITPDHIGPIE
                     HPSFEDYFYHKRLLMENSRAVIINSDMDHFSVLKEQVEDQDHDFYGSQFDNQIENSKA
                     FSFSATGKLAGDYDIQLIGNFNQENAVAAGLACLRLGASLEDIKKGIAATRVPGRMEV
                     LTQKNGAKVFIDYAHNGDSLKKLINVVETHQTGKIALVLGSTGNKGESRRKDFGLLLN
                     QHPEIQVFLTADDPNYEDPMAIADEISSYINHPVEKIADRQEAIKAAMAITNHELDAV
                     IIAGKGADCYQIIQGKKESYPGDTAVAENYL"
     gene            17757..19379
                     /locus_tag="VQ540_001436"
     CDS             17757..19379
                     /locus_tag="VQ540_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HET2545226.1"
                     /translation="MSHENNHQQAQMLRGTAWLTASNFISRLLGAVYIIPWYIWMGAY
                     AAKANGLFTMGYNIYAWFLLVSTAGIPVAVAKQVAKYNTMREEEHSFALIRSFLGFMT
                     GLGLVFALVLYVFAPWLADLSGVGKDLIPIMQSLAWGVLIFPSMSVIRGFFQGMNNLK
                     PYAMSQIAEQVIRVIWMLLATFIIMKLGSGDYLAAVTQSTFAAFVGMVASFAVLIYFL
                     AQEGSLKRVFETGDKINSKRLLVDTIKEAIPFILTGSAIQLFQILDQLTFINSMSWFT
                     NYSNEDLVVMFSYFSANPNKITMILISVGVSIGSVGLPLLTENYVKGDLKAASRLVQD
                     SLTLLFMFLLPATVGVVMVGEPLYTVFYGKPDSLALGLFVFAVLQSIILGLYMVLSPM
                     LQAMFRNRKAVLYFIYGSIAKLVLQLPTIALFHSYGPLISTTIALIIPNVLMYRDICK
                     VTGVKRKVILKRTILISLLTLVMFLLIGTIQWLLGFFFQPSGRLWSFFYVALVGAMGG
                     GLYMVMSLRTYLLDKVIGKAQADRLRAKFKLS"
BASE COUNT         6133 a         3647 c         4452 g         5255 t
ORIGIN      
        1 ccaaggtgaa cgcggtttaa ctggagctaa aggtgaaaaa ggggaccaag gtgaacgcgg
       61 tctcactgga gcccaaggtg aaaaaggaga ccgaggcgaa cgtggtttaa ctggagctaa
      121 aggtgaaaaa ggagcccaag gtcaggcagg tcgtgacggt gtaactccaa ccgtaaccgt
      181 taaagataat aaaaatgacg gcactcatac tatcactatt aacgacggta gaggtaatgt
      241 tacaagtact gttgtaagag atggtttcga tggcgcaagt ccattagttg cgactcaacg
      301 aaatgacgca gataagacaa caactgttat cttctattac gataaaaatg gaaacaatga
      361 attagatgct tctgataaga aattaaaaga agttgtaatt gcagatggtg ctaaaggtga
      421 aaaaggggac aaaggtgaac aaggtcttca agggcgtgat ggtgaacaag gaccaaaagg
      481 agaagatggg aaaaccccaa cagttaaagt aactgatggt caagatggaa cgcatacaat
      541 tacaattaac gatggtaaag gtggtataac tactacagta gtaagagatg gatttgatgg
      601 tgcaagccct cttgtttcta ctcatagaaa tgaagcagat aaaacaacaa ctgttatttt
      661 ctattatgat ctaaatgata ataatcaatt tgatgaagga gatacaaaac ttaaagaagt
      721 tgttatcgca gatggaaaac aaggaccaaa aggtgacaaa ggtgataacg gaaaagatgg
      781 attcacacca gaagtaacag ttacagataa caataacgga acacacacca tcacaatcac
      841 acaaccagac aacagaccat cattaacaac aatcgttaaa aacggtgaag atggaaaaac
      901 accaaaagtc aaagcagaac gagatgatgc gaagaaacaa acaacattaa cattctacat
      961 tgacaaagat ggagatggaa gttacacagc aggaaaagac gagttagttc aaacaacagt
     1021 agttaaagac ggacaagacg gagctgcagg agcatctgga cgtgatggaa aagaagtatt
     1081 aaacggaaaa gtagacccaa caacagaagg taaagatgga gacacattcg taaatacaca
     1141 aacaggagat gtattcgtta agaaaggtaa cacttgggaa ccagcaggaa acatcaaagg
     1201 accgaaaggt gacaaaggtg cagatggtgc caagggtgaa aaaggagccc aaggagaacg
     1261 cggcctgact ggagcgcaag gtgtcaaggg tgaaaaggga gatcagggtg aacgcggtct
     1321 aactggatct aaaggtgaaa aaggagacca aggtgaacgc ggtttaactg gagcgcaagg
     1381 tgccaaaggt gacaaaggtg aacaaggtct tcaaggtcgt gatggagctc aaggaccaaa
     1441 aggcgcagat ggacaaagag gaccagcggg accacaagga ccaaaaggag aacaaggtaa
     1501 tccaggaact ccaggtaaag atggaaaatc tctaattgct gttaaaaatg gaactgaaac
     1561 aaaagtctat gtagaggatc cggctagacc aggacaacca cttaatccaa accaaccatt
     1621 agcaactatc actgatggaa gaaacggtac taatggacaa tcaccaacaa ttacagcgac
     1681 acgaagtgtg caaaatggca aaaatggtgt attagtaaca attacaccag taggaggtcg
     1741 tccacaaaca acatttgtag aggatggaca aaagggtgct gatgggaaaa ccccaacagt
     1801 aacaataact gaggggcaaa acggcacaca tacattaacg gttcataatc caggaagtcc
     1861 agatgtgaca actacgatcc gtgatggagc tacaggacaa gcaggtcgtg atggtaaaga
     1921 tgtattaaac ggaaaagtaa atccacaacc aaaccaaggt aaaaatggag ataaatatat
     1981 taataccgaa accggtgatg tctatgttaa aaacaatgga aactgggata aagaaggcaa
     2041 catcaaaggc cctaaagggg acaaaggtgc agatggtgct aaaggcgaaa aaggagacca
     2101 aggcgaacgc ggcctaactg gagcgcaagg agctaaaggt gcggatggcg cagtaggtcg
     2161 tgatggacgt gacggtaaag acgtgttgaa cggcaaagct aacccagaag cacatcaagg
     2221 taaagacggc gataaatacg ttaatacaga aacaggcgac gtcttcgtta agaataacgg
     2281 caactgggat aaagagggca acatcaaagg ccctaagggt gacaaaggtg aacgcggaga
     2341 agatggtaag actccagaag taactgtaac tccaggtaaa gatggccata gtactgacat
     2401 tacattcact gttccaggta aagatccagt tacagtaaat gttaaggacg gagaaaatgg
     2461 tctgaacggt aaaactccaa aagttgattt acttcgtgtc caaggaaaaa acggaaatcc
     2521 atctcataca attgtgacat tctatacaga tgaaaacaat gacggcaaat atacaccagg
     2581 aactgatgaa cttctaggtt cagaaatgat taaagatggt gctaaaggcg cggacggacg
     2641 agatggtaaa tcattgctta ctgtcaagga tggtaaagaa actaaagttt accaagaaga
     2701 tccagctaac ccaggacaac cattaaatcc agaaaaacca cttgcggtaa ttagagatgg
     2761 agtagatgga aaatcaccta cagttacagc tgttcgtaaa gatgaagcag ggcataaagg
     2821 tgtagaaatc actgttgata accatgatgg ttcacaacca actacagtct ttgttcaaga
     2881 tggtgctaag ggagaaactg gtgcaaccgg tcaggatgga caaactccta caatcactac
     2941 tcaacgtgga caagatggcc aaagcactgt tgtaactatc acaacatcag gtaaagatcc
     3001 agtaaccttc actgtaaaag atggtaagaa tggtaaagat ggccgtgcac cgaaaatcaa
     3061 agtagaagat attacttcac cttcaagaat tagacgcgat acagatgctg ctgcaactcc
     3121 aacgcgtaac ggtatccgtg ttacagttta tgatgatgtt aatgacaatg gggtatacga
     3181 cgaaggtgtc gataaagtat taaatagtaa agatatttat aacggtatag atggacgtga
     3241 tggttcagct ccaactatta ctacaaaaga taatggagat ggaactcaca ctatcacagt
     3301 tcaaaaccca gatggttctg aatcaacaac agttgttaaa gatggtaaag acggtaaaac
     3361 tgcgaatatc actacaacag aaaacccaga tggaagccac acaattacgg tgacaaatcc
     3421 agatggttca actaaagaaa ctgttgttaa aaacggtaaa gacggtaaga ctcctaaagt
     3481 tgaagtaacg gataacaacg atggaactca tactgttaaa gttacagatg gagacggcaa
     3541 tgttaccaac gctatcatca aagatggtaa agacggtaaa gctgcaacag caacaactac
     3601 tgaaaatcca gatggaagcc acacagtaac aatcactaac ccagacggaa ctaagaatga
     3661 gtttgttgtt aagaatggac gtgacggtgt tgacggacgt actccaaccg catctgttcg
     3721 tgataatgga gacggaagtc atacaatcgt tattacaaat ccagaaggtg tgacaactga
     3781 aaccacagtt cgtgatggta aatcaccaaa agtgactata actgatgaac aaaatggaac
     3841 tcataagatc tctgttctaa atggtgacgg aacaactaca acaactacag ttcgtgatgg
     3901 tagagaacca aaacttgaag ttattgataa caacgatggt tcacacacta ttaaagtgac
     3961 aggtgctgat ggtaaaggaa cgacaactac aatctttgat ggtaaatcac caaaagcgaa
     4021 catcgttgat aacggagatg gaactcatac attaacaatc gtagattctg atggtcgtga
     4081 atacaaatct attatcaaag atggtaaaga cggcaaagat agcgtttcac caactgtaac
     4141 tgttaaaaat aataacgatg gaactcacgt tgttacaatc actaatccag atggaagtaa
     4201 gacagaaatg gtgattaaag acggtaaaga tggtaaatca ccaaaagttt ctgttgaaga
     4261 taatggtgat ggtagtcata caatcacaat catcaattct gatggaactg tgacaaaaac
     4321 agttattaaa gatggtagag atggacgtga tggtcgagac ggcaaagacg gtaaagacgg
     4381 taaagatgga aaatgtggat gccaagacaa accagtaaca ccatcaaatg acaaaccagt
     4441 tcctccaaca ccaaatgtgc cgacaccaga agtaccggtt aaacctgtgc cagcgcaacc
     4501 aacaccaaat gtaccgacac cagaagtgcc agtacaacca actccagctg ttccaacacc
     4561 agaagtaccg gttaaaccag taccagcggt tccagaacaa ccagtagtac caacaccggc
     4621 tcaaccagca actccagtaa atgctaaccc agtagcacca actacaggta aagaaaaccg
     4681 tggggacaaa ttacctgaaa ctggaagcca atctgattat atctctgttc ttttaggtag
     4741 cggtattcta ttgagcctat atgtaggacg aagaaaagaa gcttaatcag ccaaaagcag
     4801 tcactaattt ctcgaaagaa gatgataagt gatagatctc gaatgaaaga atattcttag
     4861 aatgattttc ctatgatgga aaagactgct aaaaaccttg agtggtaacg ctcaaggttt
     4921 ttttggatgg ctgatgtttg tctgaaaatc ttgattgaga aataaaaagc caccctatta
     4981 ggtggctata attgatttag actttctaaa attttctatt ttttactgaa tcgcttcgac
     5041 caagtcttga gcttgttttt caagtgagtt taggactgtt tcttcaagaa ccaattttcc
     5101 gtctgcccag gcagagtcat taacacgtgc agcagtgaaa tcaccaacgc cttgtgtacg
     5161 gataaatggc aagaggtctt tgtagatagc gaaaagttga tcgtgccctg cattggctac
     5221 agatgatacg gtgacaaact tgtcttgaag ggcagaaacg ccacgcgtat cagacaagtc
     5281 aagggcacga gatagccagt caagcaagtt ttttactgta ccagggatag agaagttgta
     5341 gactggagag aaaatccaga tagcatccgc aacgagaact gcttcacgag cagcagctac
     5401 agctggatgt gttggaactt ccaaatcttg gctgaagaga ggaagggctg aataatcaag
     5461 gtagctaact tccgctttac cagcaagtgc tttctcagct tcgagcgcca tttggtggtt
     5521 gaaagaacct tgacgtagtg atccgacgat aaataatact tttttagaca tgatgtgtct
     5581 cctttttctt caaattttga gaactctctc gttgttataa aatacattac aacaaaacaa
     5641 aagaacttgc aagaaatttg ctcagagttt atttgaaaat tgtaaaattt cggaaactct
     5701 agtcatttgt gactgaaaaa gtaagaactg tttcactttc aaaatcggtt ttgtttgaag
     5761 ggagaaatag aattggttgc tcaaagcaca gctttgaggt tgcagataaa gctgacgtgg
     5821 tttgaagaga ttttcgaaga gtattcttat attcacttgt aataaagctt aatagatggt
     5881 aaaatagacg agtgaaaaaa agacaaaaca aagcaaaaaa taatctactg tggcagtatg
     5941 gtctagggat gacgattttg tttgtggtta tcagtgcttc ctttctgtat atggtttctc
     6001 ttagcatgaa accctatcaa acagctaaaa gtgaaggaga aaaattagct cagcagtatg
     6061 caggattaga gcaggccgat caggttgatt tatacaatgg cttggaatct tattacagcg
     6121 ttcttggtcg taataaacag caagaagcac ttgctgttct gattggaaaa gatgatcata
     6181 agatttacgt ttatcagcta aatcagggtg tttcacaaga aaaagcagaa acggtttcta
     6241 aggaaaaggg agctggcgaa attgacaaga ttatctttgg tcgttatcaa gataagccaa
     6301 tctgggaagt caagtcagga tctgattttt atctagtaga ttttgaaaca ggagcattgg
     6361 tcaacaagga gggcctatga aattatccaa ccgtgtttta gaaatggaag aaagtgtgac
     6421 tttggctgct ggagcccgtg ccaaagcact gaaggctgag ggtagagata ttttgtctct
     6481 aaccttgggt gagccagatt tcactactcc caaaaatatc caagatgccg ccattgcatc
     6541 gattcgagat gggcgtgctt ctttttatac agtaacctca ggtctgccag agcttaaggc
     6601 ggcggtcaat agctactttg agcgctttta cggctattct gtagcgtcaa atcaagtgac
     6661 agtcgctgcg ggagccaaat attctctcta taccttcttt atggctgtgg tcaatccagg
     6721 tgatgaagtc atcatcccaa ccccatactg ggttagctat ggagatcagg tcaagatggc
     6781 agaaggcgtt cccgtctttg tttctgctaa ggaagacaat cactttaagg tgaccgtaga
     6841 gcagttagaa gcagctcgca ctgacaagac caaggttttg gtgctgaatt cgccatctaa
     6901 tcccacaggt atgatttaca cccgtgagga actcttggca attggaaact gggctgtaga
     6961 aaatgatatt ctcatcctag cagatgatat ctatggccgc ttggtttata atggtcatga
     7021 gttcacaccg atttctagcc tatcggaagc gattcgcaag caaacagtgg tcatcaatgg
     7081 tgtgtctaaa acctatgcca tgactggttg gcggattggt tatgccgttg gagaagcaga
     7141 cattatcgct gccatgtcca agattgcagg tcaaacaact tcgaatccgt cagcagtagc
     7201 ccaatatgca gcagttgagg ctctatcagg tgagcaagat actgtagaaa gcatgcgtca
     7261 ggcctttgaa gaacgtctta ataccatcta tcccctcctt gcagaagtgc caggatttga
     7321 agtggtcaaa ccgcaagggg ccttctatct cttcccaaat gtcaaaaagg ccatggagat
     7381 gaaaggctac acggatgtga cagactttac aactgttatc ttagaagaag ccgaagtggc
     7441 cttggtaaca ggagctggat ttggagcacc agaaaatgtc cgcctcagct atgcgacaga
     7501 cctagacacg cttaaagaag cagtcgaacg cttgaaagca tttatgggta gtgagaatga
     7561 ttgatcattt tgagattaag gtaaaggatt tacaaatttc agaaggattt tataggagtt
     7621 ttctcgctcc tttggactat aaattggctt ttaagactag ttctctaatt agttttctat
     7681 ccccgaacag ccctcatcct ggtggtgatt tttggctgac tcagggaaca caagatcctg
     7741 ttcattttgc ttttttagca gaaaataagg aagaagttca ggcttgttat gaggctggct
     7801 tagaggcagg tgggcgagac aatggggctc ctggttatcg aagtgagcat ccgatttact
     7861 atgctgcttt tatgattgac ctggatggga acaatataga ggtggtttgc cataaagaat
     7921 aaaaaagaaa aggaaaaata atgacaaaac gtgtaacgat tattgacgta aaagactatg
     7981 ttggtcagga agtgacgatt ggcgcttggg ttgccaacaa atcaggaaaa gggaaaatcg
     8041 ctttcttaca attgcgtgat ggaacagcct tctttcaagg tgtggctttt aaaccaaact
     8101 ttgtcgaaaa atttggtgaa gaagtgggac ttgagaagtt tgatgttatc aaacgcttga
     8161 gccaagaaac gtctgtttat gtgacaggta ttgtcaaaga ggacgaacgt tctaaatttg
     8221 gctatgagtt ggacatcaca gacatcgaag tgatcggtga atctcaagac tacccaatca
     8281 caccaaaaga acacggaaca gactttttga tggataaccg tcacttgtgg ctacgctctc
     8341 gtaagcaagt agctgtgttg caaatccgta acgctattat ctatgcaact tatgagttct
     8401 ttgacaagaa cggttttatg aagtttgaca gcccaattct ttcaggaaat gcggcagaag
     8461 attctacaga actctttgaa actgactact tcggaacgcc agcctacttg agccaatcag
     8521 gtcaacttta cctagaagca ggggctatgg ctcttggtcg tgtctttgac tttggtccag
     8581 ttttccgtgc tgaaaaatca aaaacacgcc gtcacttgac tgagttctgg atgatggatg
     8641 ctgagtactc atacttgaca catgatgagt cgcttgactt gcaagaagct tatgtgaaag
     8701 ctcttctaca aggtgttctt gaccgcgcgc ctcaagcctt ggaaaccttg gaacgtgata
     8761 cagaactctt gaaacgctac attgcagagc cattcaaacg tatcacttac gatcaagcca
     8821 ttgacctctt gcaagagcat gaaaatgatg aagatgctga ctacgagcat cttgagcatg
     8881 gtgatgactt tgggtcacca cacgaaactt ggatttcaaa ccactttggt gtgccaacat
     8941 ttgtcatgaa ctatccagca gccatcaagg ccttctacat gaaaccagtt cctggaaatc
     9001 cagagcgcgt gctttgtgca gacttgcttg ctccagaagg ctatggagaa attatcggtg
     9061 ggtctatgcg tgaggaagat tacgatgccc ttgtcgctaa gatggatgaa cttggcatgg
     9121 atcgtacaga atatgaattc taccttgacc ttcgtaaata cggtacagtt ccacacggag
     9181 gatttggtat cggtatcgaa cgtatggtaa ccttcgcagc aggaacaaaa catatccgtg
     9241 aagctattcc attcccacgt atgttgcacc gtatcaaacc ataagaacag gaaaacgccc
     9301 atgtggcgtt ttttcgaatt ctagtgtttt tacttgcgta aaaaaaattt ttctagtata
     9361 atagtttatt gtgagcgaac ctcacttacc ccttgcaaag tcttggggtc attagaccaa
     9421 aaggaggaac atatcaatgg ctaaatacga aattctttat atcattcgtc caaacattga
     9481 agaagaagct aaaaacgctt tggtagcacg ttttgactct attttgactg acaacggtgc
     9541 aactgttgtt gaatcaaaaa cttgggaaaa acgtcgtctt gcatacgaaa tccaagattt
     9601 ccgtgaagga ctttaccaca tcgttaacgt tgaagcaaat gacgatgcag ctcttaaaga
     9661 gtttgaccgt ctttcaaaaa tcaacgctga cattcttcgt cacatgatcg tcaaaattga
     9721 cgcgtaagaa ggtaaactat gattaacaat gttgtacttg tagggcgtat gacacgtgac
     9781 gctgaattgc gttatacccc atcaaatgta gcagttgcga cttttactct tgcagtaaac
     9841 cgtacattta agagtcaaaa tggtgaacgt gaggctgatt ttatcaatgt cgttatgtgg
     9901 cgccaacagg ctgaaaatct tgctaactgg gctaaaaaag gctcacttat cggggtgaca
     9961 ggtcgtatcc agactcgtag ttacgataac cagcaaggac aacgtgtcta cgtgacagag
    10021 gtcgtggctg agaatttcca aatgttggaa agccgtagtg tgcgtgaggg tcacacaggt
    10081 ggagcttact ctgcaccaac tgcaaactat tcagcaccta caaattcagt accagacttt
    10141 tcacgtaatg aaaatccatt tggagcaaca aacccattgg atatttcaga tgatgattta
    10201 ccattctaat ggacaactaa acttataaag gagaaaaaac atggctcaac aacgtcgtgg
    10261 cggattcaaa cgccgtaaaa aagttgatta catcgcagca aacaaaattg aatatgttga
    10321 ttacaaagat actgagcttc ttagccgttt cgtttcagaa cgtgggaaaa tccttcctcg
    10381 tcgtgtaaca ggaacttcag ctaaaaacca acgtaaagta acaacagcta tcaaacgcgc
    10441 tcgcgtaatg gctttgatgc ctttcgtaaa cgaagattaa agaaaagacc cggttgggtc
    10501 tctttttcat gaacttgaaa acaagaaagc gaattaagac cccaacgggt cttttttcac
    10561 aagctttgaa atgagagagc gagttaggct cagtggctcc ctttttacga gtttgaaaac
    10621 aagagaacac attaaaagca cgatggagct ttttcataaa tatgtctttt ttttcatcca
    10681 agaaattaaa ataaaaatga taaacttttt gaaaataggg gatttgccta ctttatgata
    10741 taatggaaag agttagattg aaagaggtag tgagatggac gcgaaattaa gatacaaggc
    10801 aaagaagatc aagattgtct tttttgatat tgatgataca ttgcggaatt caaagacagg
    10861 gtttattcca actacaattc ccactgtttt taaacagttg cgtgaaaaag gaattttaac
    10921 aggaatcgcc tctggacgtg gcatttttgg tgttgttcca gagattcgtg atctcaaacc
    10981 tgactttttt gtaactttga atggggctta tatcgaagat aaaaaaggtc aggtcattta
    11041 tcagcatcag attgaaaagt catatgttga ggagtatatc tcttgggcta agcaagaagg
    11101 aattgagtat ggcttggttg ggagtcatga tgccaagttg tcgactcgca ccgatatgat
    11161 gagtgaagct atcaatccaa tttatcccga cttagatgta gatcccgatt tccatgaaaa
    11221 agaagatatc tatcagatgt ggacttttga agataaggga gatgacttgc acttgcctga
    11281 cagtctctca gacaaacttc gcatggttcg ttggcatcaa cattcgtctg atattgtgcc
    11341 gatttcaggc tccaaagcga cgggggtgga aaaggttgtg gaacaccttg gcttgaaacc
    11401 agagaaggtc atggtttttg gagatggtct caatgacttg gaactctttg attatgctgg
    11461 aatcagcgtt gccatgggaa tttctcatga taaaatcaaa gaaaaagcag attatattac
    11521 aaaaacatta gaagaagatg gcatttttga tgccttagaa gtatttggta tggtagaaaa
    11581 agaattgcat tttccacaag tagacattga aacagtagaa ggtcctcttg cgactattaa
    11641 gaccaatcac ggagacttac gtatcaagct tttccctgaa catgctccta aaacagtggc
    11701 taactttgta tctctttcaa aagatggcta ctatgatggt gtcattttcc accgtattat
    11761 caaggacttt atgatccaag gtggagaccc aactggaact ggtatgggtg gcgagtcaat
    11821 ctacggcgaa tcttttgagg atgaattctc agaagagctt tacaatatcc gtggtgctct
    11881 ttccatggca aatgctggtc caaataccaa cggcagccag ttctttatcg tgcaaaacca
    11941 acacctacct tattctaaga aagaaattac tcgtggtggt tggccagaac cgattgcaga
    12001 aatctatgcc aatcaaggtg ggacacctca cctagaccgc cgtcacacgg tttttggtca
    12061 gttagctgat gaagcatctt acgctgtctt ggatgtcatt gctgctgttg agacaggagc
    12121 tatggacaag ccagttgaag atgttgtaat tgaaactatt gaaatcgagg actaagatga
    12181 aaatcggtga taagctaaag gggcgtatta cagggattca gccctacggt gcctttgttg
    12241 agttagagac gggtgatacg gggctgattc acatttcaga aattcggaca ggatttattg
    12301 aaaatattca tgaaaccttg aaagtcgatg aagaggttca agttcaggta gtggatttag
    12361 atgaatttac ggggaaagcc agtctttcta tccgcacttt ggaggaagaa aagtaccagt
    12421 ttcctagacg gagacgcttt tcaagcgacc gctttaacta cggttttgct ccctttcgac
    12481 gaatgctacc aatctggact ggagaagccc tgcaccattt aaaaaagaag aagtagttta
    12541 gagttttata ttttttgtaa tgttaatata aatttgctat aataggacca tggaagaaga
    12601 acaattatta aaatcaggag agcgcattaa ccagctcttt tcgacagata tcaaaatcat
    12661 tcaaaataga gaggttttta gctattcggt ggatagtgtt ctcttatcac gatttccacg
    12721 ttttcctaag aaggggttga ttgtggattt ctgtgctggg aatggagcag tggggctttt
    12781 tgctagcact cgtactcaag cacagatatt gtctgttgag attcaggagc gtttggcgga
    12841 tatggctgaa cgctctgtcc gtttgaatgg attagaggag caaatgcagg tcatctgcga
    12901 tgatttgaaa aatatgcctg ctcacattca ggggagtaag gtggatatga ttttgtgtaa
    12961 tccaccctat ttcaaggtgg atccttattc taatctgaac gagagtgaac attatctctt
    13021 ggctcgacac gaaatcacga ctaatttgga agaaatctgt catagtgccc agagtattct
    13081 caagtctaat gggcgtttgg ccatggttca tcgtcctgat cgacttctgg atattttgga
    13141 tacgttaaaa cgacataatc tagcccctaa gcgcctgcag tttgtttatc caaaaagaga
    13201 aaaggaagcc aatatgcttt tgattgaggc gatcaaggat ggctcaacaa gtggctttaa
    13261 ggtcttacct cctttgattg tccacaatga tgatggctct tatacgcccg aaatcgaaga
    13321 gatttattat ggatcataag gcttatatgt acgttctgga gtgtcgtgat ggatcctact
    13381 atataggcta tacgactgat atgagaagac gcctcgctat ccacaatagt gggaagggag
    13441 ccaaatatac acgagcacgc ttgccagtca aacttatcta tgctcaaggt tttgccagta
    13501 aggaagaagc catgtcggct gaagctcttt tcaagcgtaa gaagaggcca cagaaggaag
    13561 aatttttatc tgaaaatcaa gatagaaatt tactcagtta ttttgaagaa tcgtggggag
    13621 tcctttgact cctcttacct ttgtcaaaaa gcgaaaaaaa tgctacaata aagaaaataa
    13681 acaaaatgag gtattatcat gtccaagatt ctagtatttg gtcaccaaaa tccagactca
    13741 gatgccatcg ggtcatctgt agcttttgcc taccttgcaa aagaagctta cggtttggat
    13801 acggaagctg ttgcccttgg aactccaaat gaagaaacag cctttgtctt gaactatttt
    13861 ggtgtggaag caccacgtgt tatcacttct gccaaagcag agggggcaga gcaagttatc
    13921 ttgactgacc acaatgaatt ccaacaatct gtatcagata tcgctgaagt agaagtttac
    13981 ggtgttgtag accaccaccg tgtggctaac tttgaaactg caagcccact ttacatgcgt
    14041 ttggagccag ttggatcagc gtcttcaatc gtttaccgta tgttcaaaga acatggtgta
    14101 gctgtgccta aagagattgc aggtttgatg ctttcaggtt tgatttcaga tacccttctt
    14161 ttgaaatcac caacaacaca cccaacagat aaaatcattg ctcctgaatt ggctgaattg
    14221 gctggtgtaa acttggaaga atatggtttg gcaatgttga aagctggtac caacttggct
    14281 agcaaatctg ctgaagaatt gattgacatc gatgctaaga cttttgaact caacggaaat
    14341 aatgtccgtg ttgcccaagt gaacacagtt gacatcgctg aagttttgga acgccaagca
    14401 gaaattgaag ctgcaatgca agctgccaac gaatcaaacg gctactctga ctttgtcttg
    14461 atgattacag atatcgtcaa ctcaaactca gaaatattgg ctcttggtgc caatatggac
    14521 aaggtcgaag cggctttcaa tttcaaactt gaaaacaatc atgccttcct tgctggtgcc
    14581 gtttcacgta agaaacaagt ggtacctcaa ttaactgaaa gctttaatgc gtaagatttt
    14641 gggtgtcagc tcaaaatcgg aaagtctagt ttgccttata tcgaaaggag tttcggctcc
    14701 tttttttcta ggagtgaagt atgttagaaa atggcgattt gatttttgtg agagatgggt
    14761 cagacatggg acaggccatc cagacttcca caggtaacta tagccatgtt gccatttatt
    14821 tggatgggat gatttatcat gctagtggac aggctggtgc tgtctgtcaa gaaccggcag
    14881 acttctttga gtccaatcat ttgtacgacc tctatgttta cccagaaatg gatatccagt
    14941 cggtgaagga aagagcttgc agacatcttg gagcacccta caatgcttct ttctatccag
    15001 atgcagctgg tttctactgc tcccagtata tagcagaaat cctacctatt tttgaaacta
    15061 ttcctatgaa atttggagat ggggaacagg agattagtga tttttggagg gagtattaca
    15121 tagaactagg tctgcctgtt cctctgaacc aagctgggac caatcctagt cagttggcag
    15181 catcgcctct gttacaatgt aaagaaagga atcttcatga ttcagatttt taattcatct
    15241 cgtttgacga gacagccatt tttggagaat tgatccgcta tctggaccag tatgaggatg
    15301 tgattctacg ggaaattaag gctcaatttc cagatgttgc agttgataaa ctcatggaag
    15361 agtatataaa ggcaagcttg attctacgtg aaaataagcg ctattacctc aattttccta
    15421 cgcttgaatc acttgatagt cttgaactgg atcaagagat ttttgtcaga gaagctagtc
    15481 cggtctatca agccttgttg gagcagagtt ttgagacgga attgcgcaat caaatcaatg
    15541 cagctatttt agttgaaaga cggactttgc gcgcattaaa atgaccctgt ccaattattt
    15601 ttacaaggtc aaacagcagt atcctttgac agaaaaacag caggagctct atgacatttt
    15661 aggagatgtt aatcctgagt atgcactcaa gtatatgacg gcttttttgt tgaaatttct
    15721 caaaaaagac cagcttatgc agaaatgccg tgatatcttt gtggacagtt tggttgtctt
    15781 aggctatatt gtgcaaaatg aagatagaaa gtatgagttg gctatcgatt ttgataagga
    15841 gagattaact ttctacttag cgtgatttct tgtttctgag cacattgttt gactttcctt
    15901 agtattcggt ataaactata tgtaaccggt aacacatatc ggaataaact aaaggagaca
    15961 atcatatgtc acttgaaaac aaattggaac aagcaacagg cgctgtcaaa gaaggttttg
    16021 gtaaagttac tggagacagc aagacagaac ttgaaggagc tgttgaaaaa acagttgcta
    16081 aggcaaaaga cgttgtagaa gacgcaaaag gtgctgtaga aggtgccgtt gaaggtttga
    16141 aaaacgtttt tactaaataa taggaaaaaa tcaagggttt cattttccct tgattttttc
    16201 tattcttata aataattttc tgcgacggct gtatctcctg ggtaggattc tttcttgccc
    16261 tggatgattt ggtaacaatc ggctccctta cccgcaataa taactgcatc taattcgtga
    16321 tttgtgatag ccattgccgc cttgatggct tcttggcgat ccgcaatctt ttcaacagga
    16381 tgattgatgt agctactaat ttcatctgca atggccattg ggtcttcata gttagggtca
    16441 tcagcagtca gaaagacttg aatctcaggg tgttgattga ggaggaggcc aaagtcctta
    16501 cgacgacttt ctcccttgtt tcctgttgat cccagaacca gagcaatctt tccggtttga
    16561 tgagtttcaa ccacattgat gagttttttc agactatccc cattgtgggc atagtcgatg
    16621 aagaccttgg ctccattttt ctgagtgagg acttccatac gaccaggaac gcgggttgca
    16681 gcgatgcctt ttttgatgtc ctcaagactt gctccgagac ggagacaagc aagtccagca
    16741 gcaactgcat tttcttggtt gaagttgcca atgagttgga tatcataatc tccagcgagt
    16801 ttacccgtag ctgaaaagct aaaggctttg gaattctcga tttggttatc aaattggcta
    16861 ccatagaaat catggtcttg atcttcaacc tgttctttca agactgagaa gtggtccatg
    16921 tcactgttaa tgatgactgc tcggctattt tccatcaaga gacgcttgtg gtagaaatag
    16981 tcttcaaagc tagggtgttc aatcgggccg atatggtcag gagtgatgtt aagaaagact
    17041 cctacatcaa aggtcagtcc atagactcga tggactagat aggcttgact ggagacttcc
    17101 atgatgaggt gggtacggtc attttgcaca gcctgattca tcatgtcaaa gaggtcaata
    17161 ctctcagggg ttgtcaacgc tgacttaaag aaagtctcgc catcaagagt tgtgttcatg
    17221 gtcgacaaca tagcaggtct atgcccttga gataagatgt tataggcgaa ataggttgct
    17281 gttgtcttac ccttagtacc agtaaaggca aggagtttga gtttctcttg tggattacca
    17341 tagaactcca tggcaatcaa actcatggct ttctttatat cgttcacaat gatgacaggg
    17401 atatcgactt cgtagtcctt ttcagctaca taccaagcta aaccttgtgt tatagcagaa
    17461 agaaggtatt cttttttaaa ggcagcgcct tttgcaaaaa aaagagtgtc ttctgttact
    17521 tttcggctgt cgtagctgat gctatcaaaa ataactttgc tgtagttgta gtggtaatga
    17581 ccttggtcaa taatttcgcg aaaaaggcca tctttcttta aaatatctaa tacggtttca
    17641 atcttaatca tactttctat tgtaaaccga aagtcgtaaa tttacaagta acaaggaaaa
    17701 gtttataatg gaagataagg agtttttcct agttatcaaa attgaatgag gaatctatgt
    17761 cgcacgaaaa caatcaccag caggcccaga tgttacgggg gactgcttgg ctaacggcta
    17821 gtaactttat cagtcgccta ctcggggctg tttacattat cccttggtac atctggatgg
    17881 gggcttatgc agctaaggca aatggtctct ttaccatggg ttacaatatc tatgcttggt
    17941 tcttgttggt ttcaacagcg gggattccag ttgcggtggc caagcaagtt gccaagtata
    18001 ataccatgcg agaagaagag catagctttg ccctgattcg gagcttctta ggctttatga
    18061 caggactagg cctggttttt gctttagtct tgtatgtctt tgctccttgg ctagcagact
    18121 tgtctggcgt gggcaaagac ttgatcccaa tcatgcaaag cttggcttgg ggagtcttga
    18181 ttttcccgtc tatgagtgtt atccgaggat ttttccaagg gatgaataac ctcaaaccct
    18241 atgccatgag ccaaattgct gagcaggtca ttcgtgttat ctggatgctc ctagcaacct
    18301 ttatcattat gaagctcggt tcaggagatt atctagcagc cgttacccaa tcaacctttg
    18361 ctgcctttgt cggtatggta gccagttttg cagtcttgat ttatttcctt gcccaagaag
    18421 gttcactcaa aagagtcttt gaaacaggag ataagattaa cagtaagcgt ctcttggttg
    18481 ataccattaa ggaagccatt ccttttatcc tgacagggtc tgccatccag ctcttccaga
    18541 ttttggatca gctgaccttt atcaatagta tgagctggtt taccaactac agcaatgagg
    18601 acttggttgt catgttttct tatttctcag ccaatcctaa taaaatcacg atgattttga
    18661 tttctgtagg ggtttcgatt gggagtgttg gtttgccact tttgacggaa aactatgtca
    18721 agggggactt gaaagcagct tctcgtctcg ttcaggacag tctcacccta ctctttatgt
    18781 tcttgctacc agcaacggtt ggagtggtta tggtaggaga acctctttat acggtcttct
    18841 atggtaagcc agatagtttg gctctgggct tatttgtctt tgcagttttg cagtctatta
    18901 ttttaggctt gtacatggtc ttgtctccaa tgcttcaggc catgttccgc aaccgcaagg
    18961 ccgttctcta ttttatctat ggttctattg ccaagctagt cttgcaacta cctaccatcg
    19021 ccctcttcca cagttatggt cctttgattt caacaaccat tgctctcatc attcctaacg
    19081 tcttgatgta tcgggatatt tgtaaagtaa ctggtgtcaa gcgcaaggtg attttgaagc
    19141 gaaccatttt aatcagtttg ctgaccctag tcatgtttct gttaatagga accatccagt
    19201 ggctgttagg atttttcttc caaccaagtg gacgtttgtg gagcttcttt tatgtagctc
    19261 ttgtcggtgc catggggggt ggactttata tggttatgag tctgcgtacc tatttattag
    19321 ataaggtaat aggaaaagcc caagcagatc gcctgcgagc aaaatttaag ctttcgtaag
    19381 gtagcattta taaataaaag gaataagttg aacaatcttt taggagaact tgaagcttat
    19441 tcctttttta gcgtaaaaat agctaaaatt atatttcaaa aatagaa
//
LOCUS       DAVBDR010000040        18947 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.040, whole genome shotgun sequence.
ACCESSION   DAVBDR010000040 DAVBDR010000000
VERSION     DAVBDR010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18947)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18947)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18947
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.040"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            1..186
                     /locus_tag="VQ540_001437"
                     /pseudo
     CDS             1..186
                     /locus_tag="VQ540_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="internal stop; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            104..532
                     /locus_tag="VQ540_001438"
     CDS             104..532
                     /locus_tag="VQ540_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HET2545227.1"
                     /translation="MSKSTSKRYYQVAIPFTRLFCLVLVSIDYINCLSETADKNWHKS
                     DRIFVTNTGKTVHSSILSKSLQRANERLKKPIPKHLSPHIFIHITISILSENKIPLKT
                     ITDRVGHPDSEVTNSIYTHVTKNMKDEAINVLDKVMKKIF"
     gene            complement(1024..1434)
                     /locus_tag="VQ540_001439"
     CDS             complement(1024..1434)
                     /locus_tag="VQ540_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001124848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2545228.1"
                     /translation="MPKKKIERISVIHREKILWLKWYFMRDKEKPKYSVLECKMFDAA
                     KNKDMLAYKKYATIKQITDIRVQTSEDDILTAIKEVYVYNHMNVIGACQRILFVSQSP
                     AYNKLNKWFETYSDLYFSIIPLPNMGAYHELVDS"
     gene            complement(1452..1829)
                     /locus_tag="VQ540_001440"
     CDS             complement(1452..1829)
                     /locus_tag="VQ540_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001233892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2545229.1"
                     /translation="MRKYLKEIKELQELKELLSSRNTPEVIIVEGNDDLGEFFQVDGE
                     LFSDIELLENLKKWREWEVQVIVDDWCNRGLNEYETGILYFPKHEDKMDYIRFNKGLE
                     PLYHALDEPYTTISKSEWLKLLD"
     gene            complement(1771..2199)
                     /locus_tag="VQ540_001441"
     CDS             complement(1771..2199)
                     /locus_tag="VQ540_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000918209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HET2545230.1"
                     /translation="MAGNENDGLTSKQIKFIDAMLTEPTIDKACQKAGVSRATGHKYL
                     KVAAVKKTLRLKQDEMMDKTTQMLYLASSNAVSVLNDIMMDAKINPFIRTQAAKTILE
                     QSYKTHEIFGVVRQIEELRLEIEEVSKGDQRVTRTQGIIK"
     gene            complement(2243..2848)
                     /locus_tag="VQ540_001442"
     CDS             complement(2243..2848)
                     /locus_tag="VQ540_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2545231.1"
                     /translation="MTFTTIKDDIKAFGKKKHGYMTGYIAKQEELHKQLQNGMIGEKY
                     AKDQLEAYKLEGDTYSRDTYNKIHAEIEKQHDLELEALKEKELSVTADDVAELTLLAS
                     MKMTKDELLGYFEKYKNKPLAIKKLWSIAEQYPEIAINLELFNAEQALESLILFFKRQ
                     LSYCHYSLLINGDKIQAVTTEMVVNSDAPELDRRLDEYLNK"
     gene            complement(2938..3111)
                     /locus_tag="VQ540_001443"
     CDS             complement(2938..3111)
                     /locus_tag="VQ540_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2545232.1"
                     /translation="MTENKDNKLLEMMEKGFVLYSKNGIIKYIEIPDHGSIKLKAQDG
                     QLVYKEVTTGEQC"
     gene            complement(3710..4606)
                     /locus_tag="VQ540_001444"
     CDS             complement(3710..4606)
                     /locus_tag="VQ540_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000838906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HET2545233.1"
                     /translation="MKSLQSSLGNIETFKLDELCPKHEIQLTQIKGERHVVVGWNENG
                     EVIKEVRCIPPYCEQCQEEQKKQDEEDAIADNLNAKLYLQTYNVLMSNKSYVADEFKT
                     KTFDDFNAVTSEEKRFLEFAKGQVQKYLDGMRGNTLITGGTGIGKTLLSVAIAKGINE
                     GYKTKGEPKSVLFVSLTEMIKQIKEGWNYGKGATLTEFEATELMKSVDYLIIDDLGAK
                     NAVIKPKSDWEQDLLFDVLNNRENTIFNTNLDSDELKIVYNERNYSRILKGLEGNTFK
                     AFTIKDKRYSINQLKNKVKQLK"
     gene            complement(4618..5427)
                     /locus_tag="VQ540_001445"
     CDS             complement(4618..5427)
                     /locus_tag="VQ540_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HET2545234.1"
                     /translation="MAKTKVYFWLKIDKKFFDNIFIKRLKTVPGGYTMTVIYIRLMLE
                     SLESDCILYYEGYFNNLKEELALKLDVSEDDIDMTMAYFTKCGLIQIDEDKNAELPQA
                     KAMVMSETNWASYKREQRKKGKLEEVQPSLTFSNSCPTEIEKELEIEVDKEQSPTPST
                     INQDFVNLYKSFEAETGKALSPLQIQELQYMLEDFSPELIHEALKEAVSQGKANFAYI
                     KAILNRWKQDNLLTVELVRNSRAAREAKKQQTNQLEPTSYEDWIPTQEKPF"
     gene            complement(5502..5717)
                     /locus_tag="VQ540_001446"
     CDS             complement(5502..5717)
                     /locus_tag="VQ540_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2545235.1"
                     /translation="MNELDISNTQAVFVTVILIGLLLYLNHRDRKKSAQLERENQQTI
                     ETPSEDLNPDYGRYIQLAGVDVWGRIE"
     gene            complement(5719..5919)
                     /locus_tag="VQ540_001447"
     CDS             complement(5719..5919)
                     /locus_tag="VQ540_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2545236.1"
                     /translation="MTLDLDNMTQAEFDEAMAEIQLQSPNIFQLISDFVNKKVTSVEI
                     DDLLNMKRAEQVAYIKNYKARA"
     gene            complement(5916..6107)
                     /locus_tag="VQ540_001448"
                     /pseudo
     CDS             complement(5916..6107)
                     /locus_tag="VQ540_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841301.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(6096..6386)
                     /locus_tag="VQ540_001449"
                     /pseudo
     CDS             complement(6096..6386)
                     /locus_tag="VQ540_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424675.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Rha family transcriptional regulator"
     gene            complement(6556..6708)
                     /locus_tag="VQ540_001450"
     CDS             complement(6556..6708)
                     /locus_tag="VQ540_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2545237.1"
                     /translation="MKIVTFKPTKQIDGGFYLPGIDILFVSDKADAKSTEDVILFISR
                     NGLNKS"
     gene            complement(6719..6985)
                     /locus_tag="VQ540_001451"
     CDS             complement(6719..6985)
                     /locus_tag="VQ540_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2545238.1"
                     /translation="MEILSKEIQLQGLQLLKQTLETLVELEKQRSSKLDLISRKELMD
                     LLGISATTLDNWEDLALKRYQTPMDGAKKVFYRLSDVYLFLAIK"
     gene            complement(7196..7378)
                     /locus_tag="VQ540_001452"
     CDS             complement(7196..7378)
                     /locus_tag="VQ540_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HET2545239.1"
                     /translation="MLITLSLAEKVRIKRARLQLTKKAVSEQLGIKSQTLTKVENGNY
                     DASKRIYESVMTWLVE"
     gene            7440..7943
                     /locus_tag="VQ540_001453"
     CDS             7440..7943
                     /locus_tag="VQ540_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET2545240.1"
                     /translation="MYKMNRIKQLRKENNLTQRELANETKIPYRTIQRWENGETDIKS
                     DAAQVLADYFGVSIPHLLGYSDLIADTDSDIKAMAYSHLLTFVDEKQIKEFEKEFIRA
                     NDNSDTFGDLGSGEKALEKYYQALCYLVPPFRDILARYSFLSLDEKKSVYNIIVGLSN
                     NLSKENK"
     gene            8017..9180
                     /locus_tag="VQ540_001454"
     CDS             8017..9180
                     /locus_tag="VQ540_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HET2545241.1"
                     /translation="MNIIEKIKKNGQRVYYASVYLGVDQLTGKKARTTVTATTKKGVK
                     VKARDAINTFAANGYTVKDKPTITTYNELVKVWWDSYKNTVKPNTRQSMDGLVRVHLL
                     PVFGDYKLSKLTTPILQQQVNKWADKANKGEKGAFANYSLLHNMNKRILKYGVAIQVI
                     QYNPANDVIVPRKQQKEKAAVKYLDNKELKQFLDYLDTLNQSNYENLFDVVLYKTLLA
                     TGCRISEALALEWSDIDLESGVISINKTLNRYQEINSPKSSAGYRDIPIDKATLLLLK
                     QYKNRQQIQSWKLGRSETVVFSVFTEKYAYACNLRKRLNKHFDAAGVTNVSFHGFRHT
                     HTTMMLYAQASPKDVQYRLGHSNLMITENTYWHTNQENAKKAVSNYETAISNL"
     gene            complement(9334..10638)
                     /gene="eno"
                     /locus_tag="VQ540_001455"
     CDS             complement(9334..10638)
                     /gene="eno"
                     /locus_tag="VQ540_001455"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HET2545242.1"
                     /translation="MSIITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTG
                     EHEAVELRDGDKSRYGGLGTQKAVDNVNNIIAEAIIGYDVRDQQAIDRAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEIPLYSYLGGFNTKVLPTPMMNIINGGSHSDAPI
                     AFQEFMILPVGAPTFKEALRYGAEIFHALKKILKSRGLETAVGDEGGFAPRFEGTEDG
                     VETILAAIEAAGYVPGKDVFIGFDCASSEFYDKERKVYDYTKFEGEGAAVRTSAEQID
                     YLEELVNKYPIITIEDGMDENDWDGWKALTERLGKKVQLVGDDFFVTNTDYLARGIQE
                     GAANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAGQ
                     IKTGSLSRTDRIAKYNQLLRIEDQLGEVAEYRGLKSFYNLKK"
     gene            10802..11248
                     /locus_tag="VQ540_001456"
     CDS             10802..11248
                     /locus_tag="VQ540_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000131081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HET2545243.1"
                     /translation="MTDLSKQLLEKAHGGLKINPDEQRRYLGTFEERVLGYVDIDTAN
                     SPQLEKGFLFILENLQEKAEPLFVKISPTIEFDKQVFYLKEAKETDSQATIVSEEHIT
                     SPFGLVIHSNAPVQVEEKDLRLAFPKLWEVKKEEPAKTSLWKKWFS"
     gene            complement(11245..12360)
                     /locus_tag="VQ540_001457"
     CDS             complement(11245..12360)
                     /locus_tag="VQ540_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HET2545244.1"
                     /translation="MKIVIAPDSFKESLTAQQVAEAIKRGFQQSIADVECLLCPVGDG
                     GEGTVDAIRHSLDLKEKWIQVTDPFGQKEAMRYFQKGELALFEVADLVGLGKIPLEKR
                     NPLQIQTCGIGELILHLISKGIKDIYIDVGGTASNDGGLGIAAGLGYQFYDRDGNVLP
                     ASGQSLLNLASVSTENCYKIPEGVQIHILADVVSPLCGHQGATYTFGNQKGRHPTMFA
                     VVDQAIQDFYEKFSPATLEIKGAGAGGGLAGGLCAFAQASIVSGIDTCLDLINFDKKV
                     SDADLVVVGEGRLDSQSFAGKAPIGVAKRTPVGVPVIAICGSLAEDLPPLPFENIQAV
                     FSILEKSEPLEDSLKNASLYLERTAANIGHLLNMCKI"
     gene            complement(12369..12698)
                     /locus_tag="VQ540_001458"
     CDS             complement(12369..12698)
                     /locus_tag="VQ540_001458"
                     /inference="COORDINATES: protein motif:HMM:NF019887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD hydrolase family protein"
                     /protein_id="HET2545245.1"
                     /translation="MERLAKSLGIAYFTANQLEVKEGLLTGKLVGQIISPQVKKETLE
                     KWRKKLKLSKERTVAIGDGGNNLLMLKSAELGIAFCSKEMLKKEIPHHVDKRDFLEVL
                     PLIDCLE"
     gene            complement(12652..13014)
                     /locus_tag="VQ540_001459"
     CDS             complement(12652..13014)
                     /locus_tag="VQ540_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IB family phosphatase"
                     /protein_id="HET2545246.1"
                     /translation="MSQVKGLCVLDVDGTLILEEVIDLLGREAGHEAEISQITSRAMR
                     GELVFESSLRKRVSLLEGLPILVFDNVFNSIHLSLNVPEFISILQKNGILVGLVSGGF
                     TPIVGEISKIPWYCLFHC"
     gene            complement(13073..14506)
                     /gene="glgA"
                     /locus_tag="VQ540_001460"
     CDS             complement(13073..14506)
                     /gene="glgA"
                     /locus_tag="VQ540_001460"
                     /EC_number="2.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen synthase GlgA"
                     /protein_id="HET2545247.1"
                     /translation="MKILFVAAEGAPFSKTGGLGDVIGALPKSLVKAGHEVAVILPYY
                     DMVEAKFGNQIEDVLHFEVSVGWRRQYCGIKKTVLNGVTFYFIDNQYYFFRGHVYGDF
                     DDGERFAFFQLAAIEAMERIDFIPDLLHVHDYHTAMIPFLLKEKYRWIQAYEDIETVL
                     TIHNLEFQGQFSEGMLGDLFGVGFERYADGTLRWNNCLNWMKAGILYANRVSTVSPSY
                     AHEIMTSQFGCNLDQILKMESGKVSGIVNGIDADLYNPQTDALLDYHFNQEDLSGKAK
                     NKAKLQERVGLPVRADVPLVGIVSRLTRQKGFDVVVESLHHILQEDVQIVLLGTGDPA
                     FEGAFSWFAQIYPDKLSTNITFDVKLAQEIYAACDLFLMPSRFEPCGLSQMMAMRYGT
                     LPLVHEVGGLRDTVRAFNPIEGSGTGFSFDNLSPYWLNWTFQTALDLYRNHPDIWRNL
                     QKQAMESDFSWDTACKSYLDLYHSLVN"
     gene            complement(14503..15642)
                     /gene="glgD"
                     /locus_tag="VQ540_001461"
     CDS             complement(14503..15642)
                     /gene="glgD"
                     /locus_tag="VQ540_001461"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase subunit
                     GlgD"
                     /protein_id="HET2545248.1"
                     /translation="MKIDKYSAILGNTVGFHNMSTLTDHRPVASLPFGGKYRLIDFPL
                     SSLANAGVRSVFGIFQQDNISSVFDHIRSGREWGLSTFLSHYYLGIYNTRVESSTVGK
                     EYYQQLLTYLKRSGSNQTVALNCDVLINIDLNQVFHLHSTTKEPITVVYKKLAKKDIS
                     EVNAILDVDETDHVLSHKLFDSKSTAETFNMSTDIFVVDTPWLIEHLEEEAKKEHPEK
                     LRYVLRDLAVKEGAFAYEYTGYLANIHSVKSYYQANIDMLESQKFYSLFSPNQKIYTK
                     VKNEEPTYYANTSKVRTSQFASGSIIEGQVANSVLSRNIHVHKDSLVKDSLLFPRVVI
                     GEGAQVEYAILDKGVEVEPGVVIRGTAEHPVVVKKGAKVTEDIHS"
     gene            complement(15632..16774)
                     /locus_tag="VQ540_001462"
     CDS             complement(15632..16774)
                     /locus_tag="VQ540_001462"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000787267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase"
                     /protein_id="HET2545249.1"
                     /translation="MKNEMLALILAGGQGTRLGKLTQSIAKPAVQFGGRYRIIDFALS
                     NCANSGIHNVGVVTQYQPLALNNHIGNGSSWGLDGINSGVSILQPYSASEGNRWFEGT
                     SHAIYQNIDYIDSVNPEYVLILSGDHIYKMDYDDMLQSHKDNNASLTVAVLDVPLKEA
                     SRFGIMNTDANNRIVEFEEKPAQPKSTKASMGIYIFDWQRLRNMLVAAEKSKVGMSDF
                     GKNVIPNYLESGESVYAYEFSGYWKDVGTIESLWEANMEYISPENALDSRNRQWKIYS
                     RNLISPPNFLGANAHVEDSLVVDGCFVDGTVKHSILSTGAQVREGAEVLDSVIMSGAI
                     IGQGAKIKRAIIGEGAIISDGVEIDGTDEVQVVGYNEVVGVATDED"
     gene            complement(16764..18692)
                     /gene="glgB"
                     /locus_tag="VQ540_001463"
     CDS             complement(16764..18692)
                     /gene="glgB"
                     /locus_tag="VQ540_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-alpha-glucan branching protein GlgB"
                     /protein_id="HET2545250.1"
                     /translation="MDNREALKTFMTGENFYLQHYLGAHREELNGEYGYTFRVWAPNA
                     QAVHLVGDFTNWIENQIPMVRNDFGVWEVFTNMAQEGHIYKYHVTRQNGHQLMKIDPF
                     AVRYEARPGTGAIVTELPDKKWRDGLWLARRKRWGFAERPVNIYEVHAGSWKRNPDGS
                     PYSFAQLKDELIPYLVEMNYTHIEFMPLMSHPLGLSWGYQLMGYFALEHAYGRPEEFQ
                     DFVEECHTHNIGVIVDWVPGHFTINDDALAYYDGTPTFEYQDHNKAHNHGWGALNFDL
                     GKNEVQSFLISCIKHWIDIYHLDGIRVDAVSNMLYLDYDDAPWTPNKDGGNLNYEGYY
                     FLQRLNEVIKLEYPDVMMIAEESSSATKITGMKEIGGLGFDYKWNMGWMNDILRFYEE
                     DPIYRKYDFNLVTFSFMYVFKENYLLPFSHDEVVHGKKSMMHKMWGDRYNQFAGLRNL
                     YTYQICHPGKKLLFMGSEYGQFLEWKSEEQLEWSNLEDPMNAKMKYFTSQLNQFYKDH
                     RCLWEIDTSYDGIEVIDADNRDQSVLSFIRKGKKGEMLVCIFNMVPVERKDFTIGLPV
                     AGIYEEVWNTELEEWGGVWKEHNQTVQTQEGLWKDYEQTLTFTLPAMGASVWKIKRRL
                     KSTKTVTNKNQKGVENEK"
BASE COUNT         5626 a         3969 c         3191 g         6161 t
ORIGIN      
        1 agaatgggga agctagaact cttgtgtgaa tagtttgggc ataaactttt acctcttcct
       61 ccctactcac ctgagtacaa tcctattgag aaaacatggg ctcatatcaa aaagcacctc
      121 aaaaaggtat taccaagttg caataccttt tacgaggctc ttttgtcttg ttcttgtttc
      181 aattgactat ataaattgtc taagcgaaac agccgataag aattggcaca aaagcgaccg
      241 tatttttgtt accaatacag gaaaaacagt tcatagttct atcttgagca agtctctcca
      301 gcgagcaaac gaacgcctta aaaaaccaat tcccaaacat ctgtcccctc acatcttcat
      361 acacatcact attagcatct tatcagaaaa taaaattcct ttaaaaacaa tcacggacag
      421 ggttggtcat cccgactctg aagtcactaa ttccatctac acccacgtca caaagaacat
      481 gaaagatgaa gcaatcaatg tactggataa agttatgaaa aagatttttt aaaaagtttt
      541 gtcccttttt tgccctctaa atacaaaaat agcccttcgg ataaaatccg aggggctaga
      601 aacgttgtta aatcaacggc cgaacttttg aatttcatgg ttcgggataa aatagttcac
      661 tgaactattt tattttttaa ggttatcata atatcaaata gttcaattaa atacgctaaa
      721 ttactaatat actttttacc tttttcattc taaaatgtaa agtacaaaca attacaatat
      781 actagagggg gagtaaaaaa ggtaataaaa ttgacgagtt cagcaggcaa gggaaatagc
      841 acttttcatg gtgttatttt tttaattcag caatggagta gccgcttaat tgatagaaac
      901 aaaaagcacc tagtttccta gatgctagca caatagcccg gattcgaacc ggaatctcct
      961 caattaaggt gcaatcccta tatactactc attgtgcttt ggttcattat atcatacaat
     1021 caactagcta tctaccaact catgatacgc tcccatattc ggtaatggaa taatactaaa
     1081 atacaaatct gagtaagttt caaaccattt attcagcttg ttataggctg gcgactgact
     1141 aacaaataat atccgttgac aagctccgat aacattcatg tgattataca catagacctc
     1201 tttaatggcc gttaaaatat cgtcttcact tgtctgtacc ctaatatctg ttatctgctt
     1261 aatcgtagcg tattttttat aagctagcat atctttattt ttagcagcat caaacatttt
     1321 acactcaaga acactatact taggtttttc tttatctctc atgaaatacc acttgagcca
     1381 taaaattttt tctctgtgaa ttactgaaat acgttcgatt tttttctttg gcatgattac
     1441 ctcctaaatt attaatctaa tagctttaac cactcacttt ttgagattgt tgtataaggt
     1501 tcatctagcg cgtgatataa aggttctaaa cctttgttaa atcggatata gtccatttta
     1561 tcctcatgct ttggaaaata taagattcct gtttcatatt catttagacc acggttacac
     1621 caatcatcaa cgataacctg cacttcccat tcacgccact ttttaaggtt ttctaaaagt
     1681 tcaatatcac taaataactc accatcaact tggaaaaatt ctcccagatc atcgttaccc
     1741 tcgacgatga taacttcagg cgtatttcta ctacttaata attccttgag ttcttgtaac
     1801 tctttgatct cctttagata cttcctcaat ttctaacctc aattcttcaa tttgtcttac
     1861 tactccaaaa atttcatgag ttttatatga ttgttcaagt atagtttttg ctgcttgagt
     1921 tcttataaaa gggttaattt tggcatccat cataatatca ttgagtacag aaacagcatt
     1981 ggatgaggct agatatagca tctgtgtagt tttatccatc atctcatctt gttttagtct
     2041 caatgtcttt ttaacagctg caacttttag atacttatgc cctgttgccc ttgacacccc
     2101 tgctttttgg cacgctttat ctatcgttgg ctcagtaagc atggcatcta tgaattttat
     2161 ttgtttagat gtaaggccat cattttcatt tcctgccatc tattacctcc tcgttatcaa
     2221 aataaagggg ttgctagccc ctctatttgt ttaaatactc atccaaacga cggtcaagct
     2281 caggggcatc tgaatttact accatttcag ttgttacagc ttggatttta tcgccgttga
     2341 taagcaaact gtaatgacaa tatgaaagtt gccgcttaaa gaataagatt agactttcta
     2401 gcgcctgctc tgcattgaat aattccaagt tgatagcaat ttctggatat tgttcagcaa
     2461 ttgaccaaag ttttttaata gcaagaggtt tgttcttgta tttttcaaaa taacctagca
     2521 attcatcctt tgtcatcttc atactagcta acaaggtcag ctctgccacg tcatcagctg
     2581 ttacgctgag ttctttttct tttaatgcct ctagctctag atcatgctgt ttttcaattt
     2641 ctgcatgaat tttattatag gtgtccctag aataagtgtc cccctctaac ttataagcct
     2701 ctagctggtc tttagcgtat ttttcgccta tcataccatt ttgtaactgt ttatgtaatt
     2761 cctcttgttt agcaatgtag ccagtcatgt acccatgctt tttcttgcca aaagccttaa
     2821 tatcatcctt gattgttgta aatgtcatgt tatcctcctt acgaaaaaat aaaagaggta
     2881 tgacaaaaga gcgttaaact caattatcat acctctggtt tttccagtca gtatttatta
     2941 acattgttct ccagtggtca cttccttata aactaactgc ccatcttgag cttttagctt
     3001 aatgctacca tgatctggaa tttcaatgta ctttattata ccattttttg agtataaaac
     3061 aaagcctttc tccatcattt ctaataattt attatccttg ttttcagtca tgaatttctc
     3121 ctttatttca agtgtcccaa cgggtacggt tgtaagctga gacattttag ggctatcttt
     3181 gagcgacaaa aatgtcgaaa agtcttcagt tcctgtataa ccgttattag ttttgtttgc
     3241 tactcatttt tgagtcacaa atctgttaag caaaaatgag taatagctcg taagataagt
     3301 aaatctaata cttgtattcc taaagcgttg atataactga tattttcaac tatccaacgc
     3361 tctttactac cctttttagt gtgctttagc tcatttttga gcttttttga gcttttttga
     3421 gttccatttt gggaatgcaa agcaggcgcg caccgtgcat gcttttttct tgctcatagc
     3481 ctcaccctca gaagtttgcc gaccgagagc gtggggcttt ttatttttgt ataattaaaa
     3541 acagctgcac aatttttgta cagctacgac cgaggcaggg gcgacctgcc gtactttaca
     3601 ctagataata tcatctaggt agtccaactg tattttatca tattaaaggc tacattacaa
     3661 tttctcaccc tgtgaagagt gtctattttt gtttaggttt gtaagtcgat tacttcaact
     3721 gctttacctt attttttaac tgattaattg agtatcgctt atctttgatt gtgaaagcct
     3781 taaaagtgtt accctcaaga ccttttagaa tacggctata attccgctcg ttgtatacta
     3841 tcttgagttc atcgctatca agatttgtat taaatatagt attttctcga ttattcagta
     3901 catcaaaaag taaatcctgc tcccaatcgc tcttaggttt aataacagca ttttttgcac
     3961 ctaaatcatc aataattaag taatcaacag acttcatgag ttcagtagct tcaaactctg
     4021 taagtgttgc acctttacca taattccacc cctctttaat ttgtttgatc atttcggtta
     4081 ggcttacaaa aagcacactc ttaggttctc cttttgtctt atacccctca tttatacctt
     4141 tggcaatagc aactgataaa agtgtttttc caatccctgt acctcctgtg ataagcgtat
     4201 ttcccctcat gccatcaaga tatttttgta cctgaccttt tgcaaattct aaaaatcgct
     4261 tttcttctga tgttacagca ttaaaatcat caaaagtttt agttttaaac tcatctgcta
     4321 catagctctt attgctcatc aacacattat aagtttgcag atatagttta gcattcaaat
     4381 tatcagcaat cgcatcttct tcatcttgct ttttctgttc ttcttggcat tgttcacaat
     4441 agggtgggat acagcgaact tcttttatta cctctccgtt ctcattccac cccactacta
     4501 catgtctttc tcctttgatt tgtgttagct gtatttcatg cttaggacac aattcgtcta
     4561 gtttaaatgt ctcaatattt cctaaactag attgtaatga tttcattttc tgacctccta
     4621 aaatggtttt tcttgtgttg gtatccaatc ttcatagctg gtaggctcta gttgattggt
     4681 ttgctgtttt ttagcctcac gcgctgccct gctatttcta acaagttcca ccgtcaataa
     4741 attgtcctgt ttccaacggt taaggattgc cttgatgtat gcaaagtttg ctttaccctg
     4801 actgacagcc tcttttaacg cctcatggat aagctctggg ctaaaatctt ctagcatata
     4861 ctgcaattct tgaatctgta acggtgacaa tgctttacct gtctcagctt caaaagattt
     4921 atagagattt acaaaatctt gattgatggt agagggagtg ggtgattgtt ctttatctac
     4981 ttctatctct aattctttct ctatctctgt tggacatgag ttggaaaatg tcaaagatgg
     5041 ttggacttct tccaattttc ctttttttcg ttgttcacgt ttataactcg cccagtttgt
     5101 ttcactcata accatagctt ttgcctgtgg tagttctgcg tttttatctt cgtcaatctg
     5161 tattaaaccg cattttgtaa agtatgccat ggtcatatct atatcatctt ctgatacatc
     5221 taattttagg gctaactctt ccttgagatt gttaaagtag ccctcatagt ataaaataca
     5281 gtcactttcc aagctctcta acatgagcct aatataaata actgtcatag tgtacccacc
     5341 aggtaccgtc tttagtctct tgataaaaat attatcaaaa aatttcttat caatttttag
     5401 ccaaaaatag acttttgttt ttgccatcgt cctctccctt gctcatttat aattctctac
     5461 cttgattagt cttaatactc gcttgtcatt cattgttaga ctcattcaat tcttccccat
     5521 acgtctaccc ctgcaagctg gatatatcgc ccataatcag ggtttaaatc ctcgctaggt
     5581 gtttctatcg tctgttggtt ttctcgctcc agttgggcgc tttttttgcg gtctcggtgg
     5641 tttaaataaa gcagtaagcc aatcaaaatc acggtaacaa aaaccgcctg tgtattgctt
     5701 atatctagtt cattcatgtt atgccctcgc tttgtaattc ttgatgtatg ccacttgttc
     5761 agctcgcttc atattcaaca agtcgtctat ttccacactg gttacttttt tatttacaaa
     5821 atcagaaatc agttgaaaaa tgtttggact ttgtagctgg atttcagcca ttgcctcatc
     5881 aaattctgct tgtgtcatgt tgtctaaatc tagtgtcatt gcattgcctc ctcaaacttc
     5941 tctataagac aacttttatt tgctttctga gttccatttt tagagttaaa aagaatatat
     6001 tttaaggtta cagtagcctc taaatactcc ttttcagcat gctctatata cgcctgttgc
     6061 tctgcttcgt tctcaaaaaa gtgcttagct tagcgtttaa agaatgcttt gactaggttt
     6121 agtttgaatt gccgtactgc ttcggtattc tttagataag tgatcagcaa agtagcctgt
     6181 tgctcgttca gaatatagga ttttttaggt tgtcctctag tgtctaattt atggatttta
     6241 aatccaagta ttcccaactc ttcaaagtca accttatttt ctcttattaa gcgtgtgata
     6301 gtgtggtgtt gtacgtcagc acattcagcg atgatctcgc ttgtggtata cggctctttc
     6361 ttgccgtcca tgtagactag ttccattatg gttctacctc ctgtataaat ttagctagct
     6421 tactttttaa ttgtctcctc tagccctttt tagcctctac aacggttttg gctaacgtgt
     6481 tagaggcttt tataacggcc tgtatagctg tctctatttc ctccgtggaa tagtagcttt
     6541 gttttctaat atcatttaag acttgtttaa cccatttctt gaaataaata aaattacatc
     6601 ttctgtactc ttggcatctg ctttatctga gacaaataga atgtcaatgc ctggtagata
     6661 aaacccaccg tctatttgtt tagttggttt gaaagtaact attttcattt cataactcct
     6721 attttattgc taaaaataaa tacacatctg acagacgata gaatactttc ttagctccat
     6781 ccatcggggt ctgatatcgt ttaagagcaa gatcctccca gttatcaagg gttgtagcac
     6841 ttatacctag cagatccatt aattctttac gagaaattaa atctaactta ctagatcgtt
     6901 gtttttctag ctcaactaaa gtttcaagag tctgtttaag aagctgtaaa ccctgtaact
     6961 gtatttcttt agacagaatt tccatttata tcctccattt tcctttttat aaattaagtt
     7021 gtctttttcc tctaattttg ataaaataag aagagattat ttagcaaagg gggttgtccc
     7081 tttgctaaat acctaacaaa accacgcgcc ttgcctttgc ttgagttttg ttatttttcc
     7141 ttagccgtgt acgttggttt ggtcgcctgt acatggcttt ttacttgcgt taaatttatt
     7201 ctactagcca agtcatcacg ctctcataga tacgcttaga ggcatcatag tttccattct
     7261 caacttttgt tagtgtttga gatttaatac ccaactgctc cgatactgct tttttggtta
     7321 gctgtaatct tgcacgcttg atacgtactt tttcagcaag tgatagtgta atcaacattg
     7381 gtttcacctc ccttttttct ccatttttgg cattttgtgt tataatctct ttagaaagga
     7441 tgtataagat gaatagaatt aagcaattac gaaaagaaaa taatcttact caaagagaac
     7501 ttgctaatga gactaaaatc ccttatagaa ccatacaacg ttgggagaat ggggaaactg
     7561 atataaaatc cgatgctgct caggtacttg ctgactattt tggagtatca attcctcact
     7621 tactaggtta tagcgatttg atagcagata cagatagtga tattaaagca atggcatact
     7681 cacatctact aacttttgta gatgaaaaac aaatcaaaga atttgaaaaa gagttcattc
     7741 gtgcaaacga taatagtgat acttttggtg atttaggaag tggtgaaaag gcgttagaaa
     7801 aatactatca agcattatgc tatttagttc ctccttttag ggatatattg gctaggtata
     7861 gctttttgtc actagatgaa aaaaaatcag tctataatat tattgttggt ttaagtaaca
     7921 acttatcaaa agaaaataaa taactttaaa catcatgtat aaatacctaa caaaaccacg
     7981 cgccttgcct gctgatggaa agaaaggtac aaatacatga atatcataga gaaaattaaa
     8041 aagaatggcc aaagagttta ttatgctagt gtttatctag gcgttgacca actaacgggc
     8101 aaaaaagccc gtacaactgt tacagcaacc actaaaaagg gcgttaaagt aaaagcgcgt
     8161 gatgcgatca atacttttgc tgctaatggc tatacagtta aagataagcc gacaattaca
     8221 acatacaatg agcttgtaaa agtttggtgg gatagttaca agaatacagt taagccaaat
     8281 actcgccaat ccatggatgg attggttaga gtgcatttat tgcctgtatt tggcgattac
     8341 aagctatcta aacttactac gcctattctt caacagcaag taaacaaatg ggctgacaag
     8401 gcaaataaag gcgaaaaagg ggcatttgct aactactcct tgctccataa catgaataag
     8461 cgtattttga aatatggcgt agctatccag gtaatacaat acaacccagc taatgatgtc
     8521 atcgttccac gcaaacagca gaaagaaaag gctgctgtca aatacttaga caacaaagaa
     8581 ttaaaacagt ttcttgatta tttagacact ctgaatcaat caaattatga gaacttattt
     8641 gatgttgtcc tgtataagac tttattggcc actggttgcc gtattagtga ggctctagct
     8701 cttgaatggt ctgatattga cctagaaagc ggtgttatca gcatcaataa gacactaaac
     8761 cgctatcagg aaataaattc acctaaatca agcgctggtt atcgtgatat accaatagac
     8821 aaagccacat tacttttact gaaacaatac aaaaaccgtc aacaaattca gtcttggaaa
     8881 ttaggccgat ctgaaacagt tgtattctct gtatttacgg agaaatatgc ttatgcttgt
     8941 aacttacgca aacgcctaaa taagcatttt gatgctgctg gagtaactaa cgtatcattt
     9001 catggtttcc gccatacaca tactactatg atgctctatg ctcaggctag cccgaaagat
     9061 gttcagtata gattaggcca ctctaattta atgatcactg aaaatactta ctggcatact
     9121 aaccaagaga atgcaaaaaa agccgtctca aattatgaaa cagctatcag caatttataa
     9181 aaaataaggg tgacccattt ccgggctacc ctcttactat accaaaaatt agtaggggta
     9241 gtaaaaaggg tattaaatta taaaaagcac taagggaaag cgccccaaag tgcttatttc
     9301 aaaggcttta tagcctataa tcacataagg agattatttt ttaaggttgt agaatgattt
     9361 caatccacga tattcagcta cttcaccaag ttggtcttcg atacgaagca attggttgta
     9421 tttagcgatg cggtctgtac gtgaaagtga accagtcttg atttgtcctg cgttagttgc
     9481 aactgcaata tcagcgattg ttgaatcttc agtttcacct gaacggtgtg atacaacagc
     9541 agtgtaacca gcttctttag ccatttcgat agcttcaaaa gtttcagtaa gagtaccgat
     9601 ttggttaact ttgataagga ttgagttagc agcaccttct tggataccac gtgcaaggta
     9661 gtcagtgttt gttacgaaga agtcgtcacc aacaagttgt actttcttac caagacgttc
     9721 agtaagagct ttccaaccat cccagtcgtt ttcatccata ccatcttcaa tagtgatgat
     9781 tgggtatttg ttaaccaatt cttcaaggta gtcgatttgt tctgcagatg tacgaacagc
     9841 agcaccttca ccttcaaatt tagtgtagtc gtaaacttta cgttctttat cgtagaattc
     9901 tgatgaagca cagtcaaatc cgataaatac gtctttacct ggtacatatc cagcagcttc
     9961 aatcgcagca aggatagttt caacaccatc ttcagttcct tcgaaacgag gagcgaatcc
    10021 accttcgtca cctacggcag tttccaaacc acgtgattta aggattttct taagagcgtg
    10081 gaagatttca gcaccgtaac gaagggcttc tttaaatgtt ggcgcaccaa ctggcaagat
    10141 catgaactct tggaaagcga ttggagcgtc agagtgagaa ccaccgttga tgatgttcat
    10201 cattggagtt ggaagaactt tagtgttgaa tccaccaagg tagctgtaaa gtgggatttc
    10261 aaggtagtca gcagcagcac gagctacagc gatagacaca ccgaggattg cattcgcacc
    10321 caatttacct ttgttaggag taccgtcaag tgcgatcata gcacggtcaa tagcttgttg
    10381 atcacgtaca tcgtagccaa tgatagcttc agcaatgatg ttgtttacgt tgtcaacagc
    10441 tttttgtgta ccaagaccac cgtaacgaga tttgtcaccg tcgcgaagtt caactgcttc
    10501 gtgttcacca gtagaagctc ctgatggaac cataccacgt ccgaaagcac ctgattcagt
    10561 gtaaacttct acttcaagtg ttgggttacc gcgtgagtct aggacttcgc gagcgtaaac
    10621 atcagtaata attgacattt tttactctcc ttatgagtta aattttttac acctctataa
    10681 taccttaaaa cccctccttt ttcaagaaaa aacgttatct ttgtgcaact tttccttaac
    10741 tttataaagt aatcgctttc ttttgtctgt tttattctaa cttttatgat atactgtttt
    10801 catgacagat ttatcaaaac aattacttga aaaagctcat ggtgggttaa aaataaatcc
    10861 ggatgagcaa agacgctatc ttggtacttt tgaggaaaga gttcttggat atgtagatat
    10921 tgacacagca aatagccctc agttagaaaa aggcttttta tttattttag aaaaccttca
    10981 ggaaaaagca gagccactat ttgtgaagat ttcaccaact atcgaatttg ataagcaagt
    11041 tttctactta aaagaagcaa aagaaactga tagtcaagcc accatagtat ctgaagagca
    11101 tattacttct ccttttggcc tggttattca tagcaatgca ccagttcaag tagaagaaaa
    11161 agaccttcga cttgcttttc caaaactttg ggaagttaaa aaggaagaac cagccaaaac
    11221 atccttatgg aagaaatggt ttagctaaat cttgcacata tttaataagt gcccaatatt
    11281 ggcagccgtg cgctccagat agagactggc atttttcaaa ctatcttcta aaggttcact
    11341 tttctccaaa atagaaaaga cagcttggat attttcaaat ggtaggggag gtaaatcttc
    11401 agcaagacta ccgcaaatag caataacagg aactccaaca ggggttcttt ttgcaacacc
    11461 tataggcgct ttcccagcaa agctttgact atcaagtctt ccttctccaa caacaaccaa
    11521 gtcagcatct gaaactttct tatcaaagtt gattaagtcc aagcaggtat caattccaga
    11581 cacgatactt gcctgagcaa aagcacacaa accaccagca aggcctccac ctgctcctgc
    11641 tcctttaatt tctaatgttg caggtgagaa tttttcataa aaatcttgga tcgcctgatc
    11701 tacgactgca aacatagtcg gatgtcgacc tttttgattg ccaaaagtat aagtcgcacc
    11761 ttgatgacca cataagggac ttacgacatc tgctaaaata tgaatttgaa caccttcagg
    11821 aattttatag caattttctg ttgaaacaga agctaagttt aataaggatt gaccggaagc
    11881 aggcaagaca tttccatccc tatcataaaa ttgataacct aaaccagcag caatccccag
    11941 tcctccatca ttactggccg tgccaccaac atcgatataa atatctttaa tccctttaga
    12001 aatgagatgg agaatcaact ctccaatacc acaagtttgg atttgaagtg gatttcgttt
    12061 ctctagcgga atttttccaa gaccaaccaa gtcagctact tcaaatagtg ccagttcccc
    12121 tttttgaaaa tagcgcatgg cttctttttg tccaaaaggg tctgtcactt ggatccattt
    12181 ttcttttagg tcaagagaat gtcggatagc atctacagta ccttctcccc catcaccaac
    12241 agggcagagg agacattcta catctgctat cgattgttgg aagcctcttt ttattgcttc
    12301 agctacctgt tgagctgtca agctttcctt aaacgaatcc ggtgcaatta caatcttcat
    12361 attttccctc attctaaaca gtcaatcaaa ggaagaactt ctaaaaaatc cctcttgtca
    12421 acatgatgtg gtatttcttt tttgagcatt tctttggaac aaaaggcgat tcctaactcc
    12481 gccgacttca acattaatag attattgccc ccatcaccga ttgccaccgt tctttcttta
    12541 gaaagtttta gtttctttct ccatttttcc agagtttctt ttttgacctg gggacttata
    12601 atttgtccaa ctaattttcc tgttaaaaga ccttctttga cttcaagctg gttagcagtg
    12661 aaataggcaa taccaaggga ttttgctaat ctctccaact attggtgtaa atccaccaga
    12721 caccagacca actaggatac cattcttttg gagaatagag atgaactctg ggacatttag
    12781 cgatagatga attgagttga agacgttatc aaagaccaaa ataggaagac cttccaacaa
    12841 ggacactctt tttcttaaac tgctttcaaa gaccaactct cctcgcattg ctcgacttgt
    12901 aatctgcgaa atttctgcct catgacctgc ctctctccct aaaagatcaa tcacttcttc
    12961 taggattaag gttccatcta catccaaaac acacaagcct tttacttgag acatcagttc
    13021 tcctctctaa acagcctaaa aatcgtatga agtcatcata cgattttatc tattaattaa
    13081 ctaaactatg gtacaagtca aggtatgact tgcaggctgt atcccatgag aagtcactct
    13141 ccatagcttg tttttgtagg tttctccaaa tgtctggatg gtttctatac aagtccaatg
    13201 ctgtttggaa agtccaattt aaccaataag gagatagatt gtcaaagcta aagccagtac
    13261 cgcttccttc gattggattg aaagcgcgaa ctgtatctcg caagcctcca acttcatgga
    13321 ccaatggcaa ggttccataa cgcatagcca tcatttgaga caagccacac ggttcaaaac
    13381 gacttggcat gaggaagagg tcacaagcag cgtagatttc ctgagcaagt ttgacatcaa
    13441 aagtgatatt tgttgatagc ttgtctgggt aaatctgagc aaaccatgag aaagctcctt
    13501 caaaggctgg atcgccagtt cccaaaagaa caatctgaac atcttcttgc aagatatggt
    13561 gaagactttc gaccaccaca tcaaaacctt tttgacgtgt caaacgagaa acaattccca
    13621 ccagtggaac gtctgctcta acaggcaagc caactctttc ttgcaatttt gccttatttt
    13681 tggctttccc agacaaatct tcctgattga aatgatagtc taaaagagca tccgtctgag
    13741 gattataaag atcagcatca atcccattca cgataccaga tactttacca gactccattt
    13801 taagaatctg atccaaatta catccaaact gactagtcat aatttcatga gcatagctag
    13861 gtgaaacggt tgaaacacgg ttcgcataga gaatacctgc cttcatccag ttcagacagt
    13921 tgttccatcg aagggtgcca tcagcgtaac gttcaaagcc aactccaaac aaatcaccca
    13981 acattccttc tgaaaattgt ccttggaatt ctaaattatg aatggttaaa actgtttcaa
    14041 tgtcctcata ggcttgaatc caacggtatt tttccttcaa caagaaagga atcatagctg
    14101 tatggtagtc atgaacatgg agaagatcag gaataaagtc aatcctttcc atagcctcaa
    14161 tggcagccag ttggaaaaag gcaaagcgtt ctccgtcatc aaaatcaccg taaacatgac
    14221 cacggaagaa ataatattga ttgtcaataa agtagaaggt tacaccattt aatactgttt
    14281 tcttaattcc acaatactgt ctgcgccaac caacgctcac ctcaaaatga agcacatctt
    14341 caatctgatt tccaaattta gcctctacca tatcatagta gggtaaaatc actgcaactt
    14401 cgtgcccagc ttttaccagt gattttggaa gagcgccaat gacgtctccc aaaccacctg
    14461 tttttgaaaa gggtgcaccc tctgctgcta caaataaaat tttcatgaat gaatatcctc
    14521 tgttacttta gcacctttct taaccacaac tggatgttct gcagttcctc gaatcacaac
    14581 accaggctca acttcaaccc ctttgtccaa gatagcatat tcgacctgag ccccttctcc
    14641 aataacaaca cgagggaaga gcaggctatc tttaaccaag ctatccttat ggacatggat
    14701 attacgtgat agaacagaat tagctacttg accttcaata atactaccag aggcaaactg
    14761 agaagttctt accttagatg tattagcata gtaagttggc tcttcgtttt tgacctttgt
    14821 ataaatcttt tggtttggtg agaaaagaga atagaatttt tgtgattcaa gcatatcgat
    14881 attcgcttga taataagatt taacagagtg aatattggct agatagcccg tgtactcgta
    14941 ggcgaaagct ccctctttta cagccaaatc ccgtaaaaca tagcgcaatt tctctggatg
    15001 ttctttttta gcttcttctt ccaagtgttc aatcaaccaa ggtgtatcaa cgacaaagat
    15061 atctgtagac atattgaacg tttcagctgt tgacttgcta tcaaagagtt tatgagaaag
    15121 aacatggtct gtttcatcta catccaagat tgcatttact tctgaaatat ctttcttagc
    15181 tagtttttta taaactacag tgataggctc ttttgttgta ctatgtaggt ggaaaacttg
    15241 gttcaaatca atgttaataa gaacatcgca gttgagggca accgtttggt ttgagccaga
    15301 acgtttcaaa taagtaagaa gctgttggta gtattctttt ccaactgtac tactttctac
    15361 acgggtattg taaattccta gatagtaatg gctaagaaag gttgataagc cccactcgcg
    15421 tcctgaacga atatggtcaa atactgagct gatattatcc tgctggaaaa taccaaagac
    15481 actacgaaca cctgcattag caaggcttga aagtgggaag tcaatcaaac gatatttccc
    15541 accaaatggc aaacttgcta ctggacggtg gtccgtcaat gtcgacatat tgtgaaaacc
    15601 aactgtattt cctaaaatgg cagaatattt atcaatcttc atctgttgct acccccacta
    15661 cttcattata tcctacaact tgtacttcat ctgttccatc aatttcgaca ccgtcagaaa
    15721 taatcgcacc ttcaccaata atggcacgtt taatcttagc tccttgacca atgatagctc
    15781 cactcatgat aactgaatca aggacttccg ctccttcgcg aacttgcgcg cctgttgaaa
    15841 ggatagaatg tttaacagtt ccatcaacga aacatccgtc tacaactaat gagtcttcca
    15901 catgagcatt tgccccgagg aagtttggtg gtgaaatcaa gtttcttgag taaatcttcc
    15961 attgacggtt acgactatcc aaggcatttt ctggagaaat atactccatg ttcgcttccc
    16021 aaagtgactc aatagtacca acatctttcc aataaccact aaattcgtaa gcataaacac
    16081 tttcacctga ctcaaggtaa tttggaatga catttttacc aaagtctgac atgccaacct
    16141 tgctcttttc agcagcgact aacatattac gaaggcgttg ccaatcaaaa atgtagattc
    16201 ccatagaagc ttttgtagat ttaggttgag ctggtttttc ttcaaattca acaatacgat
    16261 tgttagcatc tgtgttcatg ataccaaaac ggcttgcttc tttaagaggg acgtctaaaa
    16321 ctgctactgt caagctggca ttattatcct tatgagactg gagcatatca tcatagtcca
    16381 ttttgtagat gtgatcccca gacaaaatca agacatactc aggattgaca ctgtcgatat
    16441 agtcgatatt ttggtaaata gcgtgactag tcccctcaaa ccaacgattt ccttcacttg
    16501 cagaataagg ttgaagaata gagacacctg aattaatacc gtctagtccc cagcttgaac
    16561 cattcccaat atggttgttg agagcaagtg gttgatactg tgtaacgacc ccaacattat
    16621 gaatccctga gttggcacag tttgataggg caaagtcaat gatacggtag cgcccaccaa
    16681 attgcacagc tggttttgcg atgctttgag tgagtttacc gagacgagtt ccttgcccac
    16741 cagcaagaat caaagctaac atttcatttt tcattttcta ctcctttttg gtttttattt
    16801 gtgacggttt tagtagattt caagcgacgt ttgattttcc atacacttgc tcccatagcc
    16861 ggtagggtaa aggttaaggt ctgctcataa tctttccata gtccttcttg cgtttgaaca
    16921 gtttgattat gttctttcca aacgcctccc cactcttcca actcagtatt ccatacttct
    16981 tcgtaaattc ctgcaacggg tagtccgatt gtaaaatctt tccgctcaac aggtaccatg
    17041 ttaaagatac agactaacat ttctcccttt ttacccttac gaataaagga aagaacactc
    17101 tggtctcgat tatccgcatc aatgacttca ataccatcat agctggtatc gatttcccac
    17161 agacagcgat gatctttgta aaactggttt agctgagaag tgaaatactt catcttagca
    17221 ttcattgggt cttctaggtt agaccattcc aactgttctt cagatttcca ttctaggaat
    17281 tgaccgtatt cgctacccat gaagagcaat ttcttaccag ggtgacaaat ttggtacgta
    17341 tagagattgc gcaagcctgc gaattgattg taacgatctc cccacatctt atgcatcata
    17401 ctcttcttgc catgaaccac ttcatcgtgc gagaatggca agagataatt ctccttgaaa
    17461 acatacataa agctgaaagt caccaggtta aagtcatatt tacgataaat cggatcttct
    17521 tcgtagaaac ggaggatatc attcatccag cccatgttcc atttgtagtc aaatcctaga
    17581 ccaccaatct ctttcattcc cgtaatcttg gttgcagacg aactttcttc tgcaatcatc
    17641 atcacatctg gatattctaa cttaataact tcattcaagc gttgaaggaa ataataacct
    17701 tcatagttga gatttccgcc atctttatta ggtgtccatg gagcatcatc atagtccaaa
    17761 tagagcatgt tgctaacagc atccacacga ataccatcca aatgatagat atcaatccaa
    17821 tgcttaatgc aagaaattaa gaaggactgg acttcatttt ttccaaggtc aaaattaagg
    17881 gcaccccaac catggttatg agccttatta tggtcttggt attcaaaagt cggtgtccca
    17941 tcataatagg ctaaggcatc atcattgatg gtaaagtgac ctggtaccca gtccacaata
    18001 accccaatat tatgggtatg acactcctcg acaaaatctt gaaactcctc tggtctacca
    18061 taggcatgct ctaaagcgaa gtaacccata agctggtacc cccaactcaa acctagtggg
    18121 tgggacatca agggcataaa ctcaatatga gtatagttca tctcaactag gtaaggaatg
    18181 agttcatctt tcaattgggc aaaactataa ggactgccat caggatttct cttccaagag
    18241 ccagcatgaa cctcgtaaat attgacagga cgttcagcaa agccccaacg ttttcttcgt
    18301 gccagccaaa gtccatccct ccatttctta tcaggaagct ctgttacgat tgcccctgtt
    18361 cctggacgag cctcatacct gacagcaaaa gggtcaatct tcatcagttg atgaccattt
    18421 tgacgtgtga catgatattt gtaaatatgc ccttcttgag ccatattggt aaagacttcc
    18481 cagaccccaa agtcatttct taccattgga atctgatttt caatccaatt ggtaaaatca
    18541 ccaaccaagt gaacagcctg agcattaggt gcccaaacac ggaaggtata gccatactct
    18601 ccatttagtt cttccctatg tgctcctaga taatgttgga gataaaaatt ttcacccgtc
    18661 ataaaggttt ttaatgcttc tctattatcc atatactccc tttctcctgt aagcgttttc
    18721 tatgttttta ttatactacc tttttagaga agattcaagt aaattactat acttctttaa
    18781 ttattttgaa aatctacaac aagttcactt actcgttcaa ttgtaaatca atattttttc
    18841 aaaaaattgc gaaaacacct ttctttttct actatagtga aatgaaataa aacatgcgca
    18901 aatcgattaa ggaatttaat ctaatttcta acaatgtctt agaaatc
//
LOCUS       DAVBDR010000041        18899 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.041, whole genome shotgun sequence.
ACCESSION   DAVBDR010000041 DAVBDR010000000
VERSION     DAVBDR010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18899)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18899)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18899
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.041"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            complement(47..1402)
                     /gene="rlmD"
                     /locus_tag="VQ540_001464"
     CDS             complement(47..1402)
                     /gene="rlmD"
                     /locus_tag="VQ540_001464"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HET2545251.1"
                     /translation="MNLKVKQKIPLKIKRMGINGEGIGFYQKTLVFVPGALKGEDIYC
                     QITSIRRNFVEAKLLKVNKKSKFRIVPSCTIYNECGGCQIMHLHYDKQLEFKTDLLHQ
                     ALKKFAPAGYENYEIRPTIGMQEPKYYRAKLQFQTRKFKNQVKAGLYAQNSHYLVELK
                     DCLVQDKETQVIANRLAELLTYHQIPITDERKVLGVRTIMVRRARKTGQVQIIIVTNR
                     QLNLTQLVKELVKDFPEVVTVAVNTNTAKTSEIYGEKTEIIWGQESIQEGVLNYEFSL
                     SPRAFYQLNPEQTEVLYSEAVKALDVDKEDHLIDAYCGVGTIGFAFAKKVKTLRGMDI
                     IPEAIEDAKRNAKRMGFDNTHYEAGTAEEIIPRWYKEGYRADALIVDPPRTGLDDKLL
                     DTILTYVPEKMVYISCNVSTLARDLVRLVEVYDLHYIQSVDMFPHTARTEAVVKLIKK
                     V"
     gene            1440..2216
                     /gene="recX"
                     /locus_tag="VQ540_001465"
     CDS             1440..2216
                     /gene="recX"
                     /locus_tag="VQ540_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000705102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HET2545252.1"
                     /translation="MKITKLEKKKRLYLMELDNGDKCYITEDTIVRFMLSRDKVISEE
                     ELKEIQDFAQFSYGKNLALYHLSFKARTEKEVREYLKKYDIDKNIVSQVIANLKEDKW
                     INDGQYAYAIINANQLSGDKGPYVLTQKLAQKGISKSTIEEILNDFDFSEVAQRVANK
                     LLKKYEGKLPARALQDKIIQNLTNKGFSYFDAKIAFDELDSQVDEETTQELIFKELDK
                     QYTKYARKYEGYKLKQRLTQVLARKGYDFSDIASALREYL"
     gene            2305..2838
                     /locus_tag="VQ540_001466"
     CDS             2305..2838
                     /locus_tag="VQ540_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HET2545253.1"
                     /translation="MKLPKEGDFITIQSYKHDGSLHRTWRDTMVLKTTENAIIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNIIAMIRDNGTSYYCNMASPYYLDEEALKYI
                     DYDLDVKIFTDGEKRLLDVEEYERHKRKMNYSDDLDYILKEHVKILVDWINNGRGPFS
                     EAYVNIWYKRYVELKNR"
     gene            complement(3278..4034)
                     /locus_tag="VQ540_001467"
                     /pseudo
     CDS             complement(3278..4034)
                     /locus_tag="VQ540_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000567550.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
     gene            complement(4172..5794)
                     /gene="groL"
                     /locus_tag="VQ540_001468"
     CDS             complement(4172..5794)
                     /gene="groL"
                     /locus_tag="VQ540_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166362.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HET2545254.1"
                     /translation="MSKEIKFSSDARSAMVRGVDILADTVKVTLGPKGRNVVLEKSFG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     IKNVTAGANPIGIRRGIETAVAAAVEALKNNAIPVANKEAIAQVAAVSSRSEKVGEYI
                     SEAMEKVGKDGVITIEESRGMETELEVVEGMQFDRGYLSQYMVTDSEKMVADLENPYI
                     LITDKKISNIQEILPLLESILQSNRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITEDLGLELKDATIEALGQAARVTVDKDSTVIVEGA
                     GNPEAISHRVAVIKSQIETTTSEFDREKLQERLAKLSGGVAVIKVGAATETELKEMKL
                     RIEDALNATRAAVEEGIVAGGGTALANVIPAVATLELTGDEATGRNIVLRALEEPVRQ
                     IAHNAGFEGSIVIDRLKNAELGIGFNAATGEWVNMIDQGIIDPVKVSRSALQNAASVA
                     SLILTTEAVVANKPEPVAPAPAMDPSMMGGMM"
     gene            complement(5810..6094)
                     /gene="groES"
                     /locus_tag="VQ540_001469"
     CDS             complement(5810..6094)
                     /gene="groES"
                     /locus_tag="VQ540_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HET2545255.1"
                     /translation="MLKPLGDRVVLKIEEKEQTVGGFVLAGSAQEKTKTAQVVATGQG
                     VRTLNGDLVAPSVKTGDRVLVEAHAGLDVKDGDEKYIIVGEANILAIIEE"
     gene            complement(6364..6759)
                     /locus_tag="VQ540_001470"
     CDS             complement(6364..6759)
                     /locus_tag="VQ540_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HET2545256.1"
                     /translation="MYNKVIMIGRLTSTPELHKTNNDKSVARATIAVNRRYKDQNGER
                     EADFVNMVLWGRLAETLASYATKGSLISVDGELRTRRFEKNGQMNYVTEVLVTGFQLL
                     ESRAQRAMRENNAGQDLADLVLEEEELPF"
     gene            complement(6837..7598)
                     /locus_tag="VQ540_001471"
     CDS             complement(6837..7598)
                     /locus_tag="VQ540_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HET2545257.1"
                     /translation="MAKNVVITGATSGIGEAIARAYLEQGEDVVLTGRRIDRLEILKS
                     EFAVSFPNQTVWTFPLDVTDMVMVKTVCSDILETIGRIDILVNNAGLALDLAPYQDYE
                     ELDMLTMLDTNVKGLMAVTRCFLPAMIKVNQGHIINMGSTAGIYAYAGAAVYSATKAA
                     VKTFSDGLRIDTIATDIKVTTIQPGIVETDFSTVRFHGDKERAASVYQGIEALQAQDI
                     ADTVVYVTSQPRRVQITDMTIMANQQATGFMIHKK"
     gene            complement(7631..8257)
                     /locus_tag="VQ540_001472"
     CDS             complement(7631..8257)
                     /locus_tag="VQ540_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 and tRNA-binding domain-containing
                     protein"
                     /protein_id="HET2545258.1"
                     /translation="MIFTYNKEHVSDVLMVIVKNSGDAKLNVERKGKVARVFLKENGE
                     TVAWNIFEVSSLFEIAERGQVFLSDEQVARLNQELQAEGFTEEIVNDKEPKFVVGEIV
                     EMVAHPDSDHLNICQVAVASDKIVQIVAGAPNARVGLKTIVALPGAMMPKGNFIFPGE
                     LRGEKSFGMMCSPRELHLPNAPQKRGVLELSEDQVVGTPFDPAKHWTA"
     gene            complement(8273..8590)
                     /locus_tag="VQ540_001473"
     CDS             complement(8273..8590)
                     /locus_tag="VQ540_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000615765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HET2545259.1"
                     /translation="MIQPASLEELASLVEKAGKKVFLFVADWCGDCRYIYPALPEIEE
                     TNPEFTFIRMDRDQYMDLAKLWDVYGIPSLVVLEKDKEIGRFVNRDRKSKEQINDFLA
                     GLK"
     gene            complement(8587..8886)
                     /locus_tag="VQ540_001474"
     CDS             complement(8587..8886)
                     /locus_tag="VQ540_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4651 domain-containing protein"
                     /protein_id="HET2545260.1"
                     /translation="MNGMKAKKMWMAGLALLGIGSLALATKKVADDRKLMKTQEELTE
                     IVRDHFSDMGEIATLYVQVYESSLESLVGGVIFEDGRHYTFVYENEDLVYEEEVL"
     gene            complement(9171..9362)
                     /locus_tag="VQ540_001475"
     CDS             complement(9171..9362)
                     /locus_tag="VQ540_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000291825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein"
                     /protein_id="HET2545261.1"
                     /translation="MYYSVDDVVSNAFKKRMILDSFFAFNCSGTMKVSTWVYDKGEWY
                     YVSSSGSMIANDWVKDNGK"
     gene            complement(9523..10197)
                     /locus_tag="VQ540_001476"
     CDS             complement(9523..10197)
                     /locus_tag="VQ540_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2545262.1"
                     /translation="MKKKAFGIVLLVLAAWILLQGNFGIPSLDGKIWPLLGIVFFAYK
                     SIESILRRHLTSAVFTGLLALIIANYAYDLLPVTNHSLIWASILVVLGVGYLTHSSKF
                     WNEKKWWYNGKKTVVTDKEVAFGSGTFYKQDQDLVDDQVEVAFGDAKIYYDNAEMLGD
                     FATLNIEVAFGNATVYVPQHWRVDLKVETSFGAAKADAPVAPTSKTLTIRGDVAFGKL
                     EIVYVK"
     gene            complement(10203..10649)
                     /locus_tag="VQ540_001477"
     CDS             complement(10203..10649)
                     /locus_tag="VQ540_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET2545263.1"
                     /translation="MKLRIEIDGNLEETEIVIKTPTLTDEIADLQRLLQESKAPRLTF
                     YKGTGEYYLDLSEILFFETEGSKIYAHNQKEAYEVRLKLYELESILPRYFNRVSKSTI
                     ANIRQIYSVDKSFSGTGTISFYQTHKEVHVSRHYQSLLKENLRNMR"
     gene            complement(10751..11266)
                     /locus_tag="VQ540_001478"
     CDS             complement(10751..11266)
                     /locus_tag="VQ540_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HET2545264.1"
                     /translation="MKNYQEWYRNISSRLTSRPILLFLLRSFNRLMTVAMPLVYLILL
                     VTTYLQLGLGQQVGVCVLIPASGFVALSLFRKKINHPRPYETWDICPLLDKDSSGRSM
                     PSRHVFSATIISMACLHASLPIGLVCLIFSALLGLVRVLGGVHYPKDVLVGYACGLVW
                     GFLFFLFLHVS"
     gene            complement(11263..11625)
                     /locus_tag="VQ540_001479"
     CDS             complement(11263..11625)
                     /locus_tag="VQ540_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 family protein"
                     /protein_id="HET2545265.1"
                     /translation="MSQKLYNMKFAAVYLALIAKVERKGGKAESVHQVTSWLTGYEVS
                     DVLACLDRDVTYGDFFRQAPYYVPERIAITGKICSVRIEEIDDPLMQEIRRLDKLVDW
                     LAKGKTSQQVLEKYEKHK"
     gene            complement(11691..13550)
                     /locus_tag="VQ540_001480"
                     /pseudo
     CDS             complement(11691..13550)
                     /locus_tag="VQ540_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001850459.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein/permease"
     gene            complement(13567..14037)
                     /locus_tag="VQ540_001481"
     CDS             complement(13567..14037)
                     /locus_tag="VQ540_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HET2545266.1"
                     /translation="MDKPMLVFKRFGHQIHLMVQKEAKRCGIEFMGGPQGQVVHFLDN
                     REKNQDLVLIKDIEQELNITKSVASNLVKRIVQNGLVELEASPVDKRAKFVRLTDKAR
                     SQMQQVKAFFERIDKQLMEDIDEDELLIFEKVLGQLQANIKGIGGENKEISQKN"
     gene            complement(14161..14877)
                     /locus_tag="VQ540_001482"
     CDS             complement(14161..14877)
                     /locus_tag="VQ540_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HET2545267.1"
                     /translation="MGRKWANIVAKKTAKDGANSKVYAKFGVEIYVAAKKGDPDPESN
                     SALKFVIDRAKQAQVPKHIIDKAIDKAKGNTDETFTEGRYEGFGPNGSMLIVDTLTSN
                     VNRTAANVRAAFGKNGGNMGASGSVSYLFDNKGVIVFGGEDADAVFEQLLEADVDVDD
                     VEAQEGTITVYTAPTDLHKAIVALRESGIEEFQVTELEMIPQSEVELSGEDLETFEKL
                     YSVLEDDEDVQKIYTNVDGF"
     gene            complement(15758..17167)
                     /gene="ply"
                     /locus_tag="VQ540_001483"
     CDS             complement(15758..17167)
                     /gene="ply"
                     /locus_tag="VQ540_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cholesterol-dependent cytolysin pneumolysin"
                     /protein_id="HET2545268.1"
                     /translation="MANKAVNDFILAMNYDKKKLLTHQGESIENRFIKEGNQLPDEFV
                     VIERKKRSLSTNTSDISVTATNDSRLYPGALLVVDETLLENNPTLLAVDRAPMTYSID
                     LPGLASSDSFLQVEDPSNSSVRGAVNDLLAKWHQDYGQVNNVPARMQHEKITAHSMEQ
                     LKVKFGSDFEKIGNSLDIDFNSVHSGEKQIQIVNFKQIYYTVSVDAVKNPGDVFQDTV
                     TVEDLRQRGISAERPLVYISSVAYGRQVYLKLETTSKSDEVEAAFESLIKGVAPQTEW
                     KQILDNTEVKAVILGGDPSSGARVVTGKVDMVEDLIQEGSRFTADHPGLPISYTTSFL
                     RDNVVATFQNSTDYVETKVTAYRNGDLLLDHSGAYVAQYYITWDELSYDHQGKEVLTP
                     KAWDRNGQDLTAHFTTSIPLKGNVRNLSVKIRECTGLAWEWWRTVYEKTDLPLVRKRT
                     ISIWGTTLYPQVEDKVEND"
     gene            complement(17178..17510)
                     /locus_tag="VQ540_001484"
     CDS             complement(17178..17510)
                     /locus_tag="VQ540_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2545269.1"
                     /translation="MYICIDNSMTKNKELVKNQTFKPALLTRRLVKNFMIEEPDLARN
                     PFTRPTLIDLDKVFMLDNTVIPTSYLARRRRNVSEELYEEILDYLVQPRLISLNKSEF
                     MQLNPGTY"
     gene            complement(17581..18189)
                     /locus_tag="VQ540_001485"
     CDS             complement(17581..18189)
                     /locus_tag="VQ540_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2545270.1"
                     /translation="MSQSSYLSPLLWLKKEADKEKMSATQCQIFFFYYQMFELLFARE
                     SDMKDLCLGTKGFYFSQLEKNLLSGVSRFLKNLEGKVTLKANQEVSARKALFLALTTS
                     QSDWQELAPVFDFYQTIGRLENPSLLSSQDRQHLMWIYQSALEKDYIVKVIGDKHFVL
                     KRQDATKLTARQTQTLEILSQSEDLVNPVYVTLGEKGVLLLD"
     gene            complement(18202..18660)
                     /locus_tag="VQ540_001486"
     CDS             complement(18202..18660)
                     /locus_tag="VQ540_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000186958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4231 domain-containing protein"
                     /protein_id="HET2545271.1"
                     /translation="MTPEEMYLTERLDVQIAHFLKKSVQHRRRYKVLKITEIVAGFLI
                     AVFCAIPMPGDRYRLISVALSSLGLLCEGIINLYNAKENWISYQKTAQLLEKEKFLYQ
                     CQTEKYAGKTKAFALFVKTCEGLISEEINQWESIQSKEVAASADAPVKKE"
     gene            18785..>18899
                     /locus_tag="VQ540_001487"
     CDS             18785..>18899
                     /locus_tag="VQ540_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
                     /protein_id="HET2545272.1"
                     /translation="MNYEASKQLTDTRFKRLVGVQRTTFEEMLAVLKTAYQK"
BASE COUNT         5561 a         4190 c         3433 g         5715 t
ORIGIN      
        1 aactcttact attatacagt ctttttatgt tttgtcaaca ccttttttaa acttttttta
       61 ttaattttac aacagcttca gttcgagctg tatgtgggaa catatcgacc gactggatat
      121 aatgaagatc atagacttct actaagcgta ccaaatcacg agccaaggtc gaaacattac
      181 aagaaatata aaccattttt tctggtacat aagtaagaat agtatctaat aacttatcat
      241 ccagacctgt acgtggtggg tcaacaatca aagcatctgc tcggtagcct tccttgtacc
      301 aacgaggaat aatctcttct gccgttccag cttcataatg agtattgtca aatcccattc
      361 ttttagcatt tcgcttggca tcttcaatag cttctggaat aatatccata cctctgagtg
      421 tttttacttt ctttgcaaag gcaaatccaa tcgttccaac tccacaataa gcgtcaatca
      481 aatggtcttc tttatcaaca tccagcgctt ttactgcttc gctatagagg acttctgttt
      541 gctcaggatt tagttgataa aaagctcgag gggatagtga aaattcataa ttgagtacac
      601 cttcttgaat actctcttgc ccccagataa tctctgtctt ttcaccatat atctcactgg
      661 ttttagctgt atttgtatta acagctactg tcacaacttc tgggaaatct ttaaccaact
      721 cttttaccaa ttgagttaaa ttaagctggc ggtttgtaac aataataatc tgaacctgtc
      781 cggtctttct cgcgcgtcgg accataatag tacggacacc tagaactttt ctctcatccg
      841 tgattggaat ctggtgataa gtaagtaatt ctgctaagcg attagcaatc acttgggttt
      901 ccttatcttg taccaggcag tctttcaact ctactaaata gtgagagttt tgtgcatata
      961 agcccgcctt gacctgattt ttaaattttc gagtctgaaa ttgtaactta gctctgtaat
     1021 attttggttc ctgcattcca atagttggac gaatttcata attttcatat cctgcaggag
     1081 caaatttttt cagcgcttga tgaagtaagt ccgtcttgaa ctccagctgc ttatcataat
     1141 gcaggtgcat gatttggcag cctccgcatt cattataaat agtacaagat ggcacaattc
     1201 gaaatttaga cttcttgttg accttcagta attttgcttc aacaaagttg cgtctaatag
     1261 aagtaatctg acaatagata tcttcgcctt tgagagctcc tggtacaaag actaatgttt
     1321 tttggtaaaa gccgattccc tcaccgttaa ttcccatgcg cttgattttt aatggtattt
     1381 tttgtttcac tttcagattc atacccctat cttatcacat tttgagttat aatagagcta
     1441 tgaaaatcac aaaacttgaa aagaaaaaaa gactctatct gatggagctt gataatggcg
     1501 acaaatgcta tatcaccgaa gatacaattg ttcgttttat gttatcgaga gataaggtga
     1561 taagcgaaga ggaattgaaa gagattcaag actttgctca attttcttat ggtaagaatc
     1621 tggccctcta ccacttatcc tttaaagcac gcactgaaaa agaagtcaga gaatatctga
     1681 aaaaatacga tattgataaa aacatcgttt ctcaagttat tgctaatctt aaagaagata
     1741 agtggattaa tgatggtcag tacgcttatg ctatcatcaa tgccaatcaa ctttcaggag
     1801 acaagggacc ttatgtactg actcagaaat tagcacaaaa aggaatttca aaatctacta
     1861 tagaagaaat cttgaatgat tttgattttt cggaagttgc tcaacgtgta gccaataaac
     1921 tattgaaaaa atatgaggga aaacttccag ctcgtgccct gcaagataag attatccaga
     1981 acttgactaa caagggcttc tcttattttg atgctaaaat tgcctttgac gaattggata
     2041 gtcaagttga tgaagaaacg actcaggaac tcatcttcaa ggaacttgat aagcaatata
     2101 ctaagtatgc ccgaaagtat gaaggataca aactgaagca gcgtttaact caagttttag
     2161 cacgaaaggg ctacgatttt tcggatatag caagcgctct tagagaatat ctttaatatt
     2221 tccaagtgaa attcacagat tttaggtaat tttatggtac aatagtaaat gataaactta
     2281 taaattgtag aaagttggtt agttatgaag cttccaaaag aaggcgactt tattacaatt
     2341 caaagttata agcatgatgg gagtctccac cgaacttggc gggacaccat ggtactaaaa
     2401 acaacagaaa acgccattat tggtgtcaac gatcatacac ttgttaccga aagtgatggt
     2461 cgtcgttggg tcactcgaga accggctatt gtttactttc acaagaaata ttggtttaat
     2521 atcattgcca tgattcgtga taatggaact tcttactatt gcaatatggc tagcccctac
     2581 tatctggatg aagaagcact gaagtatatt gattacgatt tggatgttaa aatttttaca
     2641 gatggggaaa aacgtctctt ggacgttgaa gagtacgagc gtcacaaacg caaaatgaat
     2701 tattctgatg acttggacta tattttaaaa gaacatgtca aaattcttgt tgattggatt
     2761 aacaatggac gtggtccttt ctcagaagcc tatgtaaaca tttggtacaa gcgctatgta
     2821 gaactaaaga atcggtaaag ttgtcaaagg tcaggaacaa aatcctgacc ttgttttttt
     2881 ggtagtataa aataaattgt gtaaacacaa aaaggaataa atccattata gcagagttac
     2941 aacacatttc tataaagaaa tttattccta cgactcagtt tggcatgctt aacttcctaa
     3001 ctcaaaaaca aagcatcgat taatttatcc gttcttcttt tgaaacagat ttgaactgat
     3061 aattgctcgt tttaatttaa gaagctcttt tgagcaaaac ttcatttttt taagagtcca
     3121 acaatttctg tctatcgctt ttctactagc aaaaaacctc ccttgaggca agttttcatt
     3181 tatatatcta atttcgtaac agtatagtaa aatgaaataa ggacagtcaa atcgatttct
     3241 aacaatgttt tagaagtaga ggtgtactat tctagtttca atctactata aatttgatat
     3301 gagaatagtc tttctcaaca tccttatcca acaagcatgc tgtggcgtcc ttcttaactt
     3361 gaaccaggtc aatattctgg gcttgggctg ccatagacgc agccacaata acattgacga
     3421 tagatatcat actcctcaca catctctact gaacgtttgt agccttgatt tttcttgaaa
     3481 tcgttgggaa gatagtgggt cgtgtaaatt ttttgcacat cgattccgat gctattgatg
     3541 gtttgagaat tcttatgagg actgatggtc aaggctgaac caaagtagtc aaagcccaag
     3601 tccatagcca cttgcgctgt tttatccagt cggtagtcaa aacaaacctt gcaacggtcg
     3661 ccaccttcgg gctcctcctc tagtccccta actagttttc ggtattaatt gggttcgtag
     3721 ggagcttcta ggtactgaac cgtatttcct gtccgatcat taaaatcact aacaaatttc
     3781 ttgatgacat agacccgctt atggtattct actttgggat ggatattaga attggcaaaa
     3841 tagatgatca catctgcata cttggtcaaa tattctagtg tataggtact acaaggggca
     3901 cagcaaacat gcacgagaat ggttggccgc tgctcatttt tctcccatgc ttgtaccatt
     3961 ttctgcatga cacggtcata attaatcttc tgattggggg gcatcttgca cagaatttct
     4021 tctacatcga tcatgttctt ctcctttttc tagtcttatt ttatcatata agttagaaga
     4081 gctcaaatca atttagaagt gaatattata aaaagaaggg ttagtcattc cctccttttg
     4141 tgttttttat aagttgtttt ctatagaaag cttacatcat cccgcccatc atacttggat
     4201 ccattgctgg agctggggct actggttctg gtttattggc tacgactgct tctgttgtca
     4261 aaatcaagct ggctacagat gctgcatttt gtagggctga acgactcact ttaactggat
     4321 caatgatacc ttgatcaatc atgttaaccc actcgccagt tgctgcgttg aatcctatac
     4381 caagctcagc atttttcaaa cgatcgataa cgatagatcc ttcaaatcct gcattgtgag
     4441 caatttgacg aacgggttct tccaaagcac ggagaacaat attacgtcct gttgcttcat
     4501 ctcctgtcaa ttccaaggta gcaacagctg gaatcacatt ggcaagagct gttccaccac
     4561 ctgcaacaat accttcttca acagctgcac gagtagcgtt gagggcatct tcaatgcgga
     4621 gtttcatttc tttcaactca gtttcagttg cggctccgac cttaataacc gctacaccac
     4681 ctgacaattt ggccaagcgt tcttgcaatt tttcacggtc aaattcagaa gttgtagttt
     4741 cgatttgaga cttgataacc gcaacacggt gagaaatcgc ttcaggattt cctgcacctt
     4801 ctacaataac cgtgctatct ttgtccacgg tcactctcgc tgcttgacca agagcttcaa
     4861 ttgtcgcatc tttcaactca agaccaaggt cttctgtgat aactgttccg cctgttaaga
     4921 tggcgatatc ttcaagcatg gctttgcgac ggtcaccaaa accaggtgcc ttgactgcta
     4981 ctacgttgaa ggttccacga atcttgttca aaacaagagt tggaagagcc tcgccatcca
     5041 catcatccgc aataatcaag agtggacgat tgctttggag aatgctttcc aaaagtggca
     5101 agatttcttg gatattggaa attttcttgt ctgtaatcaa aatgtacgga ttttcaaggt
     5161 cagccaccat tttttcgcta tcagtcacca tgtactgtga aaggtaacca cggtcaaact
     5221 gcattccttc tacgacttca agctctgttt ccataccacg tgactcttcg atggtgatga
     5281 caccgtcttt gccaactttt tccattgctt cagagatgta ctcaccaact ttttcagaac
     5341 gagaagatac ggctgcaact tgagcgatag cttctttatt ggcaacaggg atggcgttgt
     5401 ttttcaaagc ttcaactgct gcggcaactg ctgtttcaat cccacgacga ataccgattg
     5461 gatttgcacc tgctgtgacg tttttgattc cttcacggac gattgcttgg gtcaaaacag
     5521 ttgcagttgt agttccatca cctgcgatat cattggtttt tgaagccact tctgatacca
     5581 atttggcacc catattttca aaatggtctt ctaattcaat ttctttggca atagtcacac
     5641 cgtcattggt aatcaatggt gagccaaatg atttttcaag aacgacattg cgaccttttg
     5701 gtcccaaggt tactttaaca gtgtctgcaa ggatatcgac accacggacc atagctgaac
     5761 gggcatctga tgaaaattta atttcttttg acatacttac tttctccttc tattcttcaa
     5821 tgattgccaa gatgttagct tcgcctacga tgatgtactt ttcatcgcca tctttgacat
     5881 caagacctgc gtgggcttca actaagacac ggtctccagt tttaacactt ggagcaacca
     5941 agtcaccgtt caaggtacga acaccttgtc cagtagccac aacttgggct gttttggttt
     6001 tttcttgggc tgaacctgcg agaacaaagc ccccaacggt ttgttctttt tcttctattt
     6061 ttaagaccac acggtcccct aatggtttca acatctgatt tcctccataa tgagatagat
     6121 attattagcg ctctttatac ctgagtgcta attcatagtt ctattgtatc acttagtcag
     6181 aaataatcaa gaaaaaagtc tgactttctc aagataaaaa gcctgagacc aactcagact
     6241 ttttaatgtt tatactcaat gaaaatcaaa gagcaaacta ggaagctagc cgcaagctgc
     6301 tcaaagcatt gctttgatgt tgtggataaa gctaacgtgg tttgaagaga ttttcgaaga
     6361 gtattaaaat ggcaattctt cctcttccaa gactaaatct gccaaatctt ggcctgcatt
     6421 attttcacgc atggcacgtt gagcacgact ttccaagagt tggaatcctg ttacaagtac
     6481 ttcggtcacg tagttcattt ggccattttt ctcaaagcga cgggtacgca attctccatc
     6541 aacggaaatg agactacctt tggttgcgta gcttgccaaa gtttctgcta gtctgcccca
     6601 taggaccata ttgacaaaat cagcttcacg ttcaccgttt tggtctttgt aacgacggtt
     6661 cacagcgata gttgctcgcg ctaccgactt gtcattgttg gttttgtgca attctggtgt
     6721 agacgttaaa cgcccaatca tgataacttt attatacata ttttcttcct cctacttatc
     6781 tattcgtagg aaatcaaaaa aagttacaga aatttgtaac ttttcgagga aatttcttat
     6841 tttttatgaa tcatgaaacc tgtcgcctgt tgattggcca taatggtcat atctgtaatc
     6901 tgaacacggc gaggctgact ggtcacatag actactgtgt ctgcaatatc ctgagcttgc
     6961 aaggcttcta ttccttggta aacggacgca gctcgctctt tatcaccatg aaaacgaaca
     7021 gttgagaaat ctgtttcgac aatcccaggc tgaatggttg tcaccttgat atccgttgcg
     7081 atggtatcaa ttcgcagtcc atccgaaaag gtcttaaccg cagccttggt agctgagtaa
     7141 acagcggcac cagcataggc gtagattcct gcggttgacc ccatattgat aatatgacct
     7201 tgattgactt ttatcattgc tggcaagaaa cagcgagtaa ccgccatcag acctttaaca
     7261 ttggtatcca acatggtcaa catatccaac tcctcatagt cttgataggg agccaagtca
     7321 agagccagtc cggcgttgtt gaccaagata tcaatcctcc ctatcgtttc tagaatatca
     7381 gagcaaacag tcttcaccat gaccatatcc gtcacatcta gtggaaaagt ccagacggtt
     7441 tgatttggaa agcttactgc aaactccgac ttgaggattt ctaatctgtc tatccgtcgt
     7501 cctgttagaa cgacatcctc accctgctcc agataagcac gcgcaatcgc ttcaccgatt
     7561 cctgaggttg ctcccgtaat cactacattt tttgccatct tatttccttc tatcagatgc
     7621 tgacaagttc ctaggcagtc cagtgtttcg ctgggtcgaa cggtgttccg acaacttggt
     7681 cttctgataa ttcaagcacc ccacgttttt gcggagcatt tggcaaatgc aattcacgag
     7741 gactacacat catcccaaaa ctcttttcac cacgaagttc gcctgggaaa atgaaattcc
     7801 cttttggcat catggcacca ggaagagcca caatggtttt caacccaaca cgcgcattag
     7861 gtgctcctgc aacgatttgc actatcttgt cacttgcgac tgcaacttgg cagatgttga
     7921 ggtggtcact gtctggatga gctaccatct cgacaatttc accaacaaca aacttaggtt
     7981 ccttatcatt aacaatttct tctgtaaaac cttccgcctg taattcttgg ttcaaacgag
     8041 cgacttgctc atctgataaa aagacttgac cgcgctctgc aatttcaaac aagctcgaaa
     8101 cctcaaaaat gttccaagcc actgtttccc cattttcttt gaggaaaaca cgggctacct
     8161 tgcctttgcg ttccacattc agtttggcat ctccgctatt tttcacgatg accataagga
     8221 catcactgac atgttctttg ttatacgtaa aaatcattgt ttcctttttc tcctatttca
     8281 atcctgctaa aaaatcgtta atttgctcct tacttttacg gtcgcgattg acaaaacgac
     8341 cgatttcctt gtccttttct agaacaacaa ggctaggaat tccgtaaaca tcccagagtt
     8401 tggccaaatc catatactga tctcggtcca ttcgaataaa ggtgaactct ggattggtct
     8461 cttcaatctc tggtaaggca ggataaatat aacgacaatc gccacaccag tctgccacaa
     8521 aaaggaagac cttcttgccc gctttttcca ctaaagatgc taattcttct aaacttgctg
     8581 gctgtatcat aagacttcct cctcatagac taggtcttca ttttcataga caaaggtata
     8641 atgacggcca tcctcaaaaa tgacgccacc aaccaagctc tccagactgc tttcgtaaac
     8701 ttgaacataa agggtcgcaa tttcccccat gtcggaaaaa tggtctcgca caatctctgt
     8761 caactcttcc tgagtcttca tgagcttacg gtcatctgca acttttttcg tagcaagagc
     8821 aaggcttccg atacctagca gagccaagcc tgccatccac atttttttag ctttcatacc
     8881 attcatttta acacaaaaaa ggcttcagga caaatgagga agcagcagaa aagcaagtaa
     8941 aaagcctctt cctttaagga aaaagacttc ttatactaag agcaaactag gaagctagcc
     9001 gcaggctgct caaaacacgg ttttgaggtt gtagataagg cgacgttgac gtggtttgaa
     9061 gagattttca aagagtatta ttcttattgc caggcaccta agttgccaac gtagtaacta
     9121 tcaggtgtgt aggtattgcg aagcatctta cctgatgaag ccagataata ctacttgcca
     9181 ttgtctttga cccaatcatt cgcaatcatg gaaccagaag aacttacata ataccattct
     9241 cccttgtcat aaacccaagt actgactttc atggttcctg agcaattaaa ggcaaaaaaa
     9301 ctgtccaata tcattcgttt tttaaaagca tttgacacta catcatctac gctgtagtac
     9361 atagatacat caaacgtaaa agccaaaata tcgaaaaata tacaactttt aaaggcagca
     9421 tttcattttt taaagtctaa caaccataga actgaaatca gagcaaggca tcaatttcct
     9481 actcttagta cgtctatttt gatggttgaa gtgaagattt ttttatttaa cgtagacaat
     9541 ttccaacttc ccaaaagcca catctccacg gatagtcaag gttttgctgg ttggggctac
     9601 aggagcgtca gccttagctg caccaaagga ggtttctact ttcaaatcta cacgccagtg
     9661 ttgtggaaca tagacggttg cattcccgaa ggccacttca atatttaaag ttgcaaaatc
     9721 acctagcatc tctgcattat catagtagat tttagcatcc ccaaaagcga cttccacttg
     9781 gtcatctacg agatcttgat cttgcttata gaaggtcccg ctaccaaaag cgacttcctt
     9841 atccgtgacg actgtttttt tcccattgta ccaccatttt ttttcattcc agaacttact
     9901 tgaatgcgtc agataaccaa caccaagtac caccaagatg ctagcccaaa taagagaatg
     9961 attggtaact ggtaacaagt cataagcgta atttgcaatg atgagcgcca gtaaacctgt
    10021 aaaaactgcc gaagtgagat gacgtctaag gatggactca atggacttat aagcaaaaaa
    10081 aacaatacct agtaaaggcc atattttacc atccaaagaa ggaattccaa aattcccttg
    10141 cagcaagatc caagctgcta aaaccaacaa aacaatacca aatgctttct ttttcatgtt
    10201 ttttacctca tgtttcttag attttctttt aggagggatt ggtaatgccg tgagacatga
    10261 acctccttgt gcgtctgata aaaggaaatg gtgcccgttc ctgaaaagga cttgtccact
    10321 gagtaaatct gacggatgtt tgcgatcgtt gacttggaaa ctcgattaaa atagcgaggc
    10381 aagatagact ccaactcata gagcttgagg cgaacctcat aagcttcctt ctggttatga
    10441 gcgtagatct tgctcccttc tgtttcaaag aagagaattt ctgacaggtc tagataatat
    10501 tcacctgtcc ccttgtaaaa agtcaacctc ggagcctttg actcttgcaa gagccgttgc
    10561 aagtctgcaa tttcatctgt caaagtgggg gtcttgatga caatttcagt ctcctctaaa
    10621 ttgccgtcaa tctcaattcg taacttcatc acatctcctt tctgactcta ctatatcaaa
    10681 gctaagttag gaatacaagg gcaaaaaagc aagtggtcaa tttgaagcag taagtggttg
    10741 taggactagc ttaacttaca tgtaagaata ggaagaaaag gaatccccac accaaaccac
    10801 aagcatagcc aaccaagaca tccttgggat aatgaacacc ccctaaaacc ctcaccaacc
    10861 ccagcaaagc tgaaaagatc aagcatacta agccaatagg tagactagca tgcagacagg
    10921 ccatggagat gatagttgcc gaaaagacat ggcgactggg catcgaccgt cccgaactat
    10981 ccttatcaag aaggggacag atatcccaag tttcataagg tctcgggtga ttgattttct
    11041 tacgaaacag ggacaaggcc acaaaacctg atgcaggaat aagcacacaa accccaactt
    11101 gctgaccaag tcctagttgc aggtaagtgg tgactagcaa gatcagatag accaggggca
    11161 tggcgactgt catcaaacga ttgaaactgc gtaataggaa taaaagaatt ggacgactag
    11221 ttagtctgga gctgatattt cgataccatt cttgataatt tttcatttat gcttctcata
    11281 cttttctaga acttgttgag atgttttccc cttggcaagc caatccacta gcttgtccaa
    11341 gcgacgtatt tcctgcatca gaggatcatc aatttcctca atacggacac tgcaaatctt
    11401 ccctgtaatt gcaattcgtt cagggacata atatggtgct tgtctaaaaa aatctccgta
    11461 agtaacatcc ctatccagac aagcaagaac atcactcact tcataccctg tcaaccaact
    11521 ggtcacttgg tgaactgact ctgcctttcc accctttcgc tcaacttttg caatcaaggc
    11581 taagtagaca gcagcaaatt tcatattgta taatttctga ctcatacttc tctctttcta
    11641 tgtgtactag tataaataag aaaaagaagg ccgtcaagcc ttcttttgat ttattcttct
    11701 gcttcatctt ctgtaaattg actattgtac aagtcagcgt agaagccacc ttgcgccatc
    11761 agttcctcat agttgccttg ctcgatgata tttccatctt tcatgaccaa gatcaagtct
    11821 gcatttcgga tggttgacaa gcggtgggca atgacaaagg atgtgcgtcc ttccatcaaa
    11881 cggtccatgg ctttttggat caattcctct gtccgtgtgt caacagaaga agtcgcctca
    11941 tccaaaatca aaagcggtgc atccttaaga agggcacgag caatagtcaa tagttgtttt
    12001 tgtcctacag acaaggtcac ggtgtcatcc aagatggtat catagccatc tggcaaggtc
    12061 ataataaagt ggtgaattcc cacagcctta ctagcttcca tcattcgttc atcactaatc
    12121 cctatttgat tatagatgag attgtctcga atagttcctt caaagagcca ggtatcctgc
    12181 aagaccattg aaaaggcatc atgcacttct gaacgcgtca tagccttggt atccacacca
    12241 tcaatgtgaa tacttccctt atcaatctca tagaatttca tcaaaagatt gacaatggtt
    12301 gtcttaccag tcccagtcgg cccaacaatg gcaacctttt gaccagcatg aactgtcgca
    12361 gagaagtcat agtcttgaac attgacaccg tccaccagaa tttctcctgc tgacacgtcg
    12421 tagaaacgtg gaatcagatt gaccagagtt gatttaccag aacctgttga cccaataaag
    12481 gccactgttt gaccagtttc tgctttaaag ctaacatgtt caataactgc ctccgaattt
    12541 gccgcatagc ggaaggtcac atccttaaac tcgacctgac ctttgaagtt ttcatcagtc
    12601 agctgcactt gaacagggtt ttggatagaa gaatgcaaat ctaaaacttg attaatccgc
    12661 ttagcagaga ccatagtttg gggaagaacg atgaagagtg ctcccatgag aaggaagtcc
    12721 atgacaacct acatggcata agacatgaaa acaatcatgt cactaaagag aggcagacgc
    12781 gctatcggag cagcgtcgtt aatcacatag gccccaatcc agtaaatcgc cacactcaaa
    12841 ccacttgaaa tccccatcat gataggattc aaaatagcca taagacggtt gacaaacaaa
    12901 tttaaacggg tcaattcatc atttactgct gcaaattttt cattttgata atcctctgca
    12961 ttgtaggtac gaacgacacg aatacctgtt aaactctcac gagtgatact gttcagttta
    13021 tctgtcagcc cctgaatcaa ggactgtttt ggaaaggcta gcgtcatcaa aacggtcgtc
    13081 atcaggacgt tgacaatcac tgccacaagt acggcccaga gccagtattc tgaatgacct
    13141 aaaatcttcc caatagccca gatagccata attggaccac acgttaccac ttgcaagtcc
    13201 atagtaatca acatttgaac ttgagtaatg tcattggtag tacgcatcaa gaggctagga
    13261 attgaaaatt tcttaatctc tgtctgcgag taatccaaaa ctcggttaaa aatatcactt
    13321 ctcagcctac tagtataaga agccgccact cgggatgcaa aaaatccaac tgcaactacg
    13381 gacaagaagg caagaaaggg cattcccatc atcatgcttg ccggctgcca caactcatct
    13441 aaattagttc cttgactacc tagcaaatcc gtaattttcg agatataggt cggcacttcc
    13501 aactctagat agaccgaaaa gcaagtaaag agaatggcta gtaaaatcat cccccattct
    13561 tttctactaa ttcttttgac taatttcttt attctctcct cctattccct tgatatttgc
    13621 ctgtagttga ccgagaactt tctcaaaaat cagtaattca tcttcatcaa tgtcttccat
    13681 caactgcttg tctatgcgtt caaaaaaagc cttaacctgt tgcatctgag aacgtgcttt
    13741 gtccgtcaga cgaacaaact tagcccgctt atcaacagga ctcgcctcca attccaccaa
    13801 accattttgc actatacgct taaccagatt actagcaaca gacttggtaa tattgagttc
    13861 ctgctcgata tctttaatca agaccaagtc ttggtttttc tcgcgattat ccaaaaaatg
    13921 cacaacctga ccttgcggcc cacccataaa ttcaatgccg caacgtttgg cttccttttg
    13981 caccatcagg tgaatttgat gaccaaaacg cttaaagact aacatcggtt tatccataat
    14041 ctcccccttc taaataaaaa tagttctctg gagaataatt aaatttctat gagaactatt
    14101 ttcttgatta aaaaaatccc aagtgatttt ctcacttagg atcatgttct ataggttaaa
    14161 ttaaaaccca tctacgttcg tataaatctt ttggacgtct tcgtcgtctt caagaacgct
    14221 gtaaagtttt tcaaaggttt caaggtcttc gcctgacaat tccacttctg actgaggaat
    14281 catttccaat tcagtcactt ggaattcttc aataccagac tcacggaggg caacgatagc
    14341 cttgtgaagg tcagttggcg ctgtgtaaac tgtgattgta ccttcttgtg cttctacgtc
    14401 atccacatcc acatccgctt cgagcaattg ctcaaagact gcgtccgcat cttcacctcc
    14461 aaatacaata acacctttgt tgtcaaagag gtaagaaaca gaacctgaag cgcccatgtt
    14521 tccgccgttt ttaccaaagg ctgcacggac attggctgct gtacggttga cgttagaagt
    14581 caaagtatcc acaattagca tagagccatt tggcccaaaa ccttcgtaac gtccttctgt
    14641 aaaggtttcg tctgtgtttc ctttggcttt atcaatcgct ttatcgataa tgtgttttgg
    14701 cacttgggct tgtttagcac ggtcgataac gaatttcaaa gctgagtttg attctggatc
    14761 tggatcacct tttttagctg ctacatagat ttctacacca aattttgcat atactttaga
    14821 gttggctcca tctttagccg ttttcttggc tacgatattg gcccatttac gtcccattag
    14881 gaatctcctt ttttcacatt ttaatctttc ttattataac acaagttttt ttgattttca
    14941 ctagaggaaa tggattttat tagcaaatca agctaggata gcactttacc tgctaagatg
    15001 gtcttgcctt tctatcttta tcaacagaca ctcatccaca ttcaaaaaac aaactagacc
    15061 attatctgca aatagaaagt ttcagccaag tttgacaaag tcagctcaaa ttactgtttg
    15121 aagtttgtag atataagcga caaaaacaat catactgcac cttttgttga cagtctactc
    15181 cagacatatc atagttcaag taaatacttt gaaatccaac agttcttata ggcgctattg
    15241 tattctaaga aatcaataga agagtttcta agcaaacctc taatactcaa taaaaatcaa
    15301 agagcaaact agaaagctag ccgcaggttg ctcaaaacac tgttttgagg ttgcggatag
    15361 ggctgacatg gtttgaagag attttcgaag agtataattt acgtgttcct aagatggaga
    15421 agttagacta gtacactggc acttctaaac cattgctagc aattgatttg ttcatattta
    15481 atttcatttt ttccataaat gggtattaga tataaacagc aaaatatttc cgatacgtgt
    15541 cattcttgaa tttccaatca tctaaaacaa gtaaaggata atcaatcccc tgtatatcaa
    15601 ggaattggct acccttttta cttttttaca catcctgttt gatagactca ttttaacatc
    15661 acgagcatac tccaatggaa atcgctaggc aagagataaa ctttcagata ttcgcagaga
    15721 gctcatcgcc tctttttgtc gcaaacattc ttctctccta atcattttct accttatcct
    15781 ctacctgagg atagagagtt gttccccaaa tagaaatcgt ccgcttacgc actagtggca
    15841 aatcggtttt ttcataaacc gtacgccacc attcccaggc aagcccggta cactctctaa
    15901 ttttgacaga gagattgcga acattccctt ttaaaggaat actagtggta aagtgagccg
    15961 tcaaatcctg cccatttctg tcccaagcct taggagtcaa gacttccttg ccttgatgat
    16021 cataggataa ttcatcccaa gtaatataat attgggcaac ataggcacca ctatgatcca
    16081 gcagtaaatc tccgtttctg taagctgtaa ccttagtctc aacatagtct gtactgtttt
    16141 gaaaggtcgc aactacattg tcacgtaaaa aagaagttgt ataggaaatc ggcaagcctg
    16201 gatgatcggc tgtaaagcga ctgccttctt gaatcaagtc ctctaccata tccaccttgc
    16261 ctgttacaac tcgggcaccc gaacttgggt cgccccctaa aataaccgcc ttcacttctg
    16321 tattgtccaa aatctgcttc cactctgtct gaggagctac tccttttatc aaagattcaa
    16381 aagcagcctc tacttcatca ctcttactcg tggtttccaa cttgagatag acttggcgcc
    16441 cataagcaac actcgaaata tagaccaaag gacgctctgc agaaattcct ctctgcctta
    16501 aatcctctac cgttacagta tcttgaaaca catctcctgg atttttaaca gcatctacgc
    16561 tgactgtata ataaatctgc ttaaaattaa caatctgaat ctgcttttcg cctgaatgga
    16621 cagagttaaa atcaatatca agagaattcc ctatcttttc aaagtcagaa ccaaacttga
    16681 ccttgagttg ttccatgctg tgagccgtga ttttttcatg ctgcattcta gctgggacat
    16741 tattgacctg accataatct tgatgccact tagccaacaa atcgtttacc gctccgcgaa
    16801 cacttgaatt gctggggtct tccacttgga gaaagctatc gctacttgcc aaaccaggca
    16861 aatcaatact ataagtcatc ggagcacgat cgaccgcaag aagagtggga ttattctcta
    16921 acaaggtctc atccactacg agaagtgctc caggatagag gcgactgtcg ttggtagctg
    16981 ttacagaaat atcacttgta tttgtcgaca agctccgctt ctttctttcg ataacaacaa
    17041 actcatcggg tagctgatta ccctctttga tgaaacgatt ttcaatactt tctccctgat
    17101 gggtcaagag tttcttttta tcgtaattca tagctagtat aaagtcattt actgctttat
    17161 ttgccatctt ctacctccta ataagttcct ggattgagtt gcataaactc agacttgttc
    17221 agcgaaatca gccgtggttg gactaagtaa tccaaaattt cctcgtacaa ttcttctgag
    17281 acattgcgtc gccgtctggc taaataagaa gtcggaatga ccgtattatc caacataaat
    17341 accttatcta agtcaatcaa ggttggtctt gtaaaaggat tacgagctag atccggctct
    17401 tctatcataa agttcttgac caaacgtctg gtcaagagag ctggtttgaa ggtctgattt
    17461 ttaaccaact ctttgttttt agtcatgctg ttgtcaatac agatatacat atgattcttc
    17521 acagccaaat cgctactaat agtcggaaaa ggcaaataaa gagctacaac atctcctctc
    17581 ttaatcaagc aagagcaccc ccttttctcc taatgtaaca tagacaggat tgaccaagtc
    17641 ttctgattga ctcagaattt ccaaagtttg agtttggcgc gctgtcaatt tagtagcatc
    17701 ttgtctcttc aatacaaaat gcttgtcgcc aataaccttg acaatataat ccttctccaa
    17761 agctgactgg taaatccaca tcagatgttg tctgtcctga gaactcaaga gagaaggatt
    17821 ttcaagcctc ccgatagtct gataaaaatc aaaaacagga gctaactcct gccaatctga
    17881 ttggctagtt gtcaaggcta gaaaaagggc tttgcgagct gatacttctt ggttagcctt
    17941 gagagttact ttcccctcca agttttttag aaatcgggaa actccagaaa gcaaattttt
    18001 ctctaactgc gagaaataaa aacctttcgt tcccagacat aagtctttca tgtcgctttc
    18061 tctagcaaat aagagctcaa acatttgata gtaaaagaaa aatatctggc actgggtcgc
    18121 gctcatcttt tccttatcgg cttctttttt taaccagagc aagggcgaca ggtagctgga
    18181 ttgagacatt tcctctacct cctactcttt tttaactgga gcatctgcac tagctgccac
    18241 ttcttttgac tggatacttt cccactggtt aatctcctct gagataagac cttcgcatgt
    18301 cttgacaaat agggcaaaag ccttggtctt tcctgcatat ttctccgttt ggcattgata
    18361 gaggaatttt tctttctcca ggagttgcgc agttttttgg taagaaatcc aattttcctt
    18421 tgcattatac aaattgataa tcccctcaca cagcaagccg agactggata aggcaaccga
    18481 aatcaaacgg tagcgatcac ctggcatagg aatagcacaa aagacagcta tgaggaaacc
    18541 tgccacgatt tctgttattt ttaatacctt atagcgccta cgatgttgaa cgcttttctt
    18601 taaaaaatga gctatctgta cgtctaatcg ctctgtcagg tacatttctt ctggcgtcat
    18661 attcgtaact cctttcattt actttgataa ccatagtata acatatttga atatcaaagt
    18721 atagtaaaaa ctggactata acttattaga ctccctgcga aacaaaatat ggtatagtag
    18781 ttctatgaat tatgaagcaa gtaaacaatt aactgataca cgatttaagc gtcttgttgg
    18841 tgttcagcgt accacttttg aagagatgtt agctgtatta aaaacagctt atcaaaaaa
//
LOCUS       DAVBDR010000042        17682 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.042, whole genome shotgun sequence.
ACCESSION   DAVBDR010000042 DAVBDR010000000
VERSION     DAVBDR010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17682)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17682)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17682
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.042"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            complement(289..1224)
                     /locus_tag="VQ540_001488"
     CDS             complement(289..1224)
                     /locus_tag="VQ540_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional biotin--[acetyl-CoA-carboxylase]
                     synthetase/biotin operon repressor"
                     /protein_id="HET2545273.1"
                     /translation="MKSYQAVYQILSKETDYISGEKIAEKLSLSRTAIWKAIKRLEQE
                     GIEIDSIKNRGYKLMNGDLILPEILEENLPIKVSFKPETKSTQLDAKEAIDLGHEANT
                     LYLASYQTAGRGRFQRSFYSPQGGIYMTLHLKPNLPYDKLPSYTLLVAGAVYKAIKNL
                     TLIDVDIKWVNDIYLNNHKIGGILTEAMTSVETGLVTDIIIGVGINFTIKDFPQELKE
                     KAASLFKATAPITRNELIIEIWRAFFETPAEELLYLYKKQSFILGKEVTFTLEQKDYK
                     GLAKDISENGKLLVQCDNGKEIWLNSGEISLNSWK"
     gene            complement(1221..2081)
                     /locus_tag="VQ540_001489"
     CDS             complement(1221..2081)
                     /locus_tag="VQ540_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000959966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HET2545274.1"
                     /translation="MLVFSEYQTGTIDLALSFYGYEECTPNYSFGPAIRDTYVLHYIT
                     KGQGKFYYKGKIVDLKEGDFFLLKPEELTFYQADSKEPWAYYWLGITGGKSPDYFALS
                     QISDQSYLIQSETCHTQTTAKLISDIVRFAQITKSSELAQLHIMGQLHELMFHLGTIA
                     PNQKKKNISSTHQLYLECKRLIDSHYPQSLTIQDLAKELSVHRSYLSSVFKEFNTLSP
                     KEYLLYVRMHRARQLLENTQESIKVIAYSVGFSDPLHFSKAYKQYFNQTPSHTRKEYS
                     QYQLVRKATL"
     gene            2189..4351
                     /locus_tag="VQ540_001490"
     CDS             2189..4351
                     /locus_tag="VQ540_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000538915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HET2545275.1"
                     /translation="MGVRIENNLFYVESKNLSLIIENRNGYLLLKHLGKTIKNYKGSN
                     SVYERDHAFSGNPTATNRTFSLDTQRQIFGQHGLGDFRKPTIQVQHSVTEVTDFRFVE
                     AKILKGQNGPQGLPSPHSMDDTETLVLMLEDSKAQLSLTLYYTTFNNDATITSYSKLD
                     NNSNQEVVIHKDFSFMADFPAADYEIATLQGAYAREKTVRRQQVEQGIFSISSNRGAS
                     GHAQTPALLLCEQGVTEDAGNVFAIQLMYSGNFEAFVQKNQLNEVRVAIGINPENFSW
                     KLAPEEYFETPVALVTHSDQGLTGISHESQNFVLKHIILSEFSKKERPILINNWEATY
                     FDFQREKLLELADEAKKVGIELFVLDDGWFGNRFDDNRALGDWVVNEEKLGGSLESLI
                     SAIHERGLQFGLWLEPEMISVDSDLYRQHPDWAIQVPDYEHTYSRNQLVLNLANPQVV
                     EYLKSVLDQLLSYHEIDYIKWDMNRNITKLGNGLTYLETQMQSHQYMLGLYELVSYLT
                     EKHSHILFESCSGGGGRNDLGMIRYFPQVWASDNTDAIARLPIQYGSSYFYPTISMGA
                     HVSAVPNHQMGRMTPLETRGHVAMMGNLGYELDLTNLSDEEKATIANQVNLYKELRPV
                     VQLGQQYRLINPDTASNEAAVQFNYGNQTIVTYVRVLSVVETMETTLKLKDLDEEGLY
                     KLQENGEVYSGAELMYAGLTVILSQGDFLSRQYIFRKL"
     gene            4443..5702
                     /locus_tag="VQ540_001491"
     CDS             4443..5702
                     /locus_tag="VQ540_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HET2545276.1"
                     /translation="MEWYKKIGLLATTGLALFGLGACSNYGKSADDTVTIEYFNQKKE
                     MTKTLEEITRDFEKENPKIKVKVVNVPNAGEVLKTRVLAGDVPDVVNIYPQSIELQEW
                     AKAGVFEDLSNKDYLKRVKNGYAEKYAVNEKVYNVPFTANAYGIYYNKDKFEELGLKV
                     PETWDEFEQLVKDIVAKGQTPFGIAGADAWTLNGYNQLAFATATGGGKEANQYLRYSQ
                     PNAIKLSDPIMKDDIKVMDILRINGSKQKNWEGAGYTDVIGAFARGDVLMTPNGSWAI
                     TAINEQKPNFKIGTFMIPGKEKGQSLTVGAGDLAWSISATTKHPKEANAFVEYMTRSE
                     VMQKYYDVDGSPTAIEGVKQAGEDSPLAGMTEYAFTDRHLVWLQQYWTSEADFHTLTM
                     NYVLTGDKQGMVNDLNAFFNPMKADVD"
     gene            5716..6582
                     /locus_tag="VQ540_001492"
     CDS             5716..6582
                     /locus_tag="VQ540_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET2545277.1"
                     /translation="MKKVLQKYWAWAFVVIPLLLQAIFFYVPMFQGAFYSFTNWTGLT
                     YNYKFVGLNNFKLLFMDPKFMNAIGFTAIITIAMVVGEIALGIFIARVLNSKIKGQTF
                     FRAWFFFPAVLSGLTVALIFKQVFNYGLPAIGNALHIEFLQTSLLGTKWGAIFAAVFV
                     LLWQGVAMPIIIFLAGLQSIPTEITEAARIDGATSKQVFWNIELPYLLPSVSIVFILA
                     LKGGLTAFDQVFAMTGGGPNNATTSLGLLVYNYAFKNNQFGYANAIAVNLFFLIVVIS
                     IIQLRVSKKFEI"
     gene            6596..7429
                     /locus_tag="VQ540_001493"
     CDS             6596..7429
                     /locus_tag="VQ540_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HET2545278.1"
                     /translation="MKQDERKALIGKYILLILGSVLILVPLLATLFSSFKSTKDIVDN
                     FFGFPTNFTWDNFSRLLADGIGGYYWNSVVITVLSLLAVMIFIPMAAYSIARNMSKRK
                     AFTIMYTLLILGIFVPFQVIMIPITVMMSKLGLANTFGLILLYLTYAIPQTLFLYVGY
                     IKISIPESLDEAAEIDGANQFTTYFRIIFPMMKPMHATTMIINALWFWNDFMLPLLVL
                     NRDSKMWTLPLFQYNYAGQYFNDYGPSFASYVVGIISITIVYLFFQRHIIAGISNGAV
                     K"
     gene            7430..7510
                     /locus_tag="VQ540_001494"
                     /pseudo
     CDS             7430..7510
                     /locus_tag="VQ540_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            7648..9090
                     /gene="gtfA"
                     /locus_tag="VQ540_001495"
     CDS             7648..9090
                     /gene="gtfA"
                     /locus_tag="VQ540_001495"
                     /EC_number="2.4.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose phosphorylase"
                     /protein_id="HET2545279.1"
                     /translation="MPIQNKTMLITYSDSLGNNLKDLYDNLEEHFGDAIGGVHLLPFF
                     PSTGDRGFAPVDYDEVDSAFGDWEDVKRLGEKYYLMFDFMINHISRQSKYYKDYQEKH
                     EASEFKDLFLNWDKFWPENRPTQSDVDLIYKRKDRAPKQEIVFEDGSVEHLWNTFGEE
                     QIDLDVTKEVTMEFIRKTIQHLASNGCDLIRLDAFAYAVKKLDTNDFFVEPDIWDLLD
                     KVRDIAAEYGTEILPEIHEHYSIQFKIADHDYYVYDFTLPMVTLYTLYSSRTERLAKW
                     LKMSPMKQFTTLDTHDGIGVVDVKDILTDEEIDYASNELYKVGANVKRKYSSAEYNNL
                     DIYQINSTYYSALGDDDVKYFLARLIQAFAPGIPQVYYVGLLAGKNDLKLLEETKEGR
                     NINRHYYSNEEIAREVQRPVVKALLNLFSFRNRSEAFDLEGTTEIETPTAHSIVIKRQ
                     NKDKSVTAVAEIDLQNQTYRVIENGVEVSF"
     gene            9228..10421
                     /locus_tag="VQ540_001496"
     CDS             9228..10421
                     /locus_tag="VQ540_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008293041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HET2545280.1"
                     /translation="MKSIGFIEKLKGLSSKELILLGIILSIFLPFYLFVVVLCLYIIS
                     LIFTGDMKSILQKMGEHPMLLLFLSYSTVISILAQNWMGLVASVGMFLFTIFFLHYQS
                     ILSHKFFRLILQFVLFGSVLSAAFASLEHFQIVKKFNYAFLSPNMQVWHQNRAEVTFF
                     NPNYYGIICCFCIMIAFYLFTTTKLNWLKVFCVIAGFVNLFGLNFTQNRTAFPAIIAG
                     AIIYLFTTIKNWKAFWLSIGVFAIGLSFLFSSDLGVRMGTLDSSMEERISIWDAGMAL
                     FKQNPFWGEGPLTYMHSYPRIHAPYHEHAHSLYIDTILSYGIVGTILLVLSSVAPVRL
                     MMDMSQESGKRPIIGLYLSFLTVVAVHGIFDLALFWIQSGFIFLLVMCSIPLEHRMLV
                     SDMTD"
     gene            11108..13087
                     /locus_tag="VQ540_001497"
     CDS             11108..13087
                     /locus_tag="VQ540_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000742236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HET2545281.1"
                     /translation="MKKNRVFATAGLVLLAAGVLAACSSSKSSDSSAPKAYGYVYTAD
                     PETLDYLISSKNSTTVVTSNGIDGLFTNDNYGNLAPAVAEDWEVSKDGLTYTYKIRKG
                     VKWFTSDGEEYAEVTAKDFVNGLKHAADKKSEAMYLAENSVKGLADYLSGTSTDFSTV
                     GVKAVDDYTLQYTLNQPEPFWNSKLTYSIFWPLNEEFETSKGSDFAKPTDPTSLLYNG
                     PFLLKGLTAKSSVEFVKNEQYWDKENVHLDTINLAYYDGSDQESLERNFTSGAYSYAR
                     LYPTSSNYSKVAEEYKDNIYYTQSGSGIAGLGVNIDRQSYNYTSKTTDSEKVATKKAL
                     LNKDFRQALNFALDRSAYSAQINGKDGAALAVRNLFVKPDFVSAGEKTFGDLVAAQLP
                     AYGDEWKGVNLADGQDGLFNADKAKAEFAKAKKALEADGVQFPIHLDVPVDQASKNYI
                     SRIQSFKQSVETVLGVENVVVDIQQMTSDEFLNITYYAANASSEDWDVSGGVSWGPDY
                     QDPSTYLDILKTTSSETTKTYLGFDNPNSPSVVQVGLKEYDKLVDEAAKETSDLNVRY
                     EKYAAAQAWLTDSSLFIPAMASSGAAPVLSRIVPFTGASAQTGSKGSDVYFKYLKLQD
                     KVVTKEEYEKAREKWLKEKAESNEKAQKELASHVK"
     gene            13154..14650
                     /locus_tag="VQ540_001498"
     CDS             13154..14650
                     /locus_tag="VQ540_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2545282.1"
                     /translation="MKKYIFMRVLRSLVSIFLVTTLTYTIIYTLVPRKLIFKQDPNYN
                     KIATTADKRDNYENTVFERMGYIEYYDTKELQEKASSMDSSVTVEANATNKAIYEKYI
                     NQLGHGWTLGEFTESGQFYATREIPIFERVFHFYANLIDIDHTNKIQDPENPDLKRYL
                     RFENDPAIGWSLVGSGTKHKYLLYFNSQFPFVHQNFVNLNLGDSYPTYANTPVLQVIT
                     QGQGQTKTAQVQFPTGKKTSSVNIYSRTYKSPSQADSREVASYGKDDPYTATESNYQY
                     PSMIVSSAITGLIGLVLAYALAVPLGSAMARFKNTWIDSLSTGALTFLLALPTIALVY
                     IVRLIGSSIALPDSFPILGAGDWRSYVLPAVILGLLGAPGTAIWIRRYMIDLQSQDFV
                     RFARAKGLSEKEISNKHIFKNAMVPLVSGIPGAIIGVIGGATLTETVFAFPGMGKMLI
                     DSVKASNNSMVVGLVFIFTCISIFSRLLGDIWMTIIDPRIKLTEKGGK"
     gene            14650..15576
                     /locus_tag="VQ540_001499"
     CDS             14650..15576
                     /locus_tag="VQ540_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2545283.1"
                     /translation="MSTIDKEKFQFVKRDDFASETIDAPAYSYWKSVFKQFMKKKSTV
                     VMLGILVAIILISFIYPMFSKFDFNDVSKVNDFSIRYIKPNAEHWFGTDSNGKSLFDG
                     VWFGARNSILISVIATVINLVIGVFVGGIWGISKSVDRVMMEVYNVISNIPPLLIVIV
                     LTYSIGAGFWNLIFAMSVTTWIGIAFMIRVQILRYRDLEYNLASRTLGTPTLKIVAKN
                     IMPQLVSVIVTTMTQMLPSFISYEAFLSFFGLGLPITVPSLGRLISDYSQNVTTNAYL
                     FWIPLTTLVLVSLSLFVVGQNLADASDPRTHR"
     gene            15585..16652
                     /locus_tag="VQ540_001500"
     CDS             15585..16652
                     /locus_tag="VQ540_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2545284.1"
                     /translation="MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALV
                     GESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDLTALSSHKDWEQIRGAKIATIFQ
                     DPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
                     SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITH
                     DLGVVASIADKVAVMYAGEIVEYGTVEEVFYDPRHPYTWSLLSSLPQLADDKGDLYSI
                     PGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSETHWAKTWLLHEDAPKVEKP
                     AVIANLHDKIREKMGFAHLAD"
     gene            16663..17589
                     /locus_tag="VQ540_001501"
     CDS             16663..17589
                     /locus_tag="VQ540_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2545285.1"
                     /translation="MSEKLVEIKDLEISFGEGSKKFVAVKNANFFINKGETFSLVGES
                     GSGKTTIGRAIIGLNDTSNGDIIFDGQKINGKKSREQAAELIRRIQMIFQDPAASLNE
                     RATVDYIISEGLYNHRLFKDEEERKEKVQNIIREVGLLAEHLTRYPHEFSGGQRQRIG
                     IARALVMQPDFVIADEPISALDVSVRAQVLNLLKKFQKELGLTYLFIAHDLSVVRFIS
                     DRIAVIYKGVIVEVAETEELFNNPIHPYTQALLSAVPIPDPILERKKVLKVYDPSQHD
                     YETDKPSMVEIRPGHYVWANQAELARYQKGLN"
BASE COUNT         5205 a         3154 c         3691 g         5632 t
ORIGIN      
        1 atgtctagta attttgtgat aaaatgtaat tgttccatat gattctttct aatgagttgt
       61 tttgtcgctt ttcattatag gtcatatggg actttttttc tacacaaaat aggctccata
      121 atatccatag ggaatttacc cactacaaat attatagagc ccgttttaat gagagtttgt
      181 aactctcttt tttgttttta gagacaataa aacttcagat ccgtaaaact taattgaatt
      241 actaatctga agttattttt atatcgttta tattataatt gtgttatttt acttccaact
      301 attgagagaa atttcgccac tatttagcca gatttctttt ccgttatcac attgaactaa
      361 aagttttcca ttttctgaga tgtctttagc aagtcccttg tagtcttttt gctctagtgt
      421 gaaagtgact tcttttccta gaatgaatga ctgttttttg tataggtata atagctcttc
      481 tgctggtgtt tcgaagaaag cacgccagat ttctatgatc aattcattcc ttgttatagg
      541 agctgtagct ttaaataagc tggcagcttt ttcttttaat tcctgaggga agtctttaat
      601 agtgaaattg atacctactc caataatgat atctgtgact aagccagttt ctacagaggt
      661 cattgcttca gtaaggattc ctccaatttt atgattgttt agatagatat cattgaccca
      721 ttttatgtcg acatctatta aagttaggtt cttaatggct ttgtagacag ctccagctac
      781 aagtagtgtg taggatggta atttgtcata ggggagattt ggtttaagat ggagtgtcat
      841 ataaatacca ccttgtggtg agtagaagga acgttgaaaa cggcctcggc ctgctgtttg
      901 ataggaagct agatagaggg tatttgcttc atggcctaaa tcaattgctt cttttgcatc
      961 tagttgtgtt gattttgttt cgggtttaaa gctgacttta attggaagat tttcttctag
     1021 aatctctgga agaataaggt caccattcat cagtttatat cctctatttt tgatactatc
     1081 aatttcaatg ccttcttgtt ctagtcgctt gatggctttc caaattgctg ttcggcttag
     1141 ggatagtttt tctgcgattt tttctccgct gatatagtcg gtttctttag ataggatttg
     1201 gtagacagct tggtaggatt tcataatgtt gcctttctca ctagttggta ttgagagtat
     1261 tcttttcttg tatgacttgg agtctgatta aagtattgtt tataagcttt cgaaaaatgg
     1321 agtggatctg aaaaacctac cgagtatgca attaccttga tggactcttg ggtattttcg
     1381 agaagttgtc tagctcggtg cattcgaacg tagagtaggt attctttggg tgataaggta
     1441 ttaaattctt tgaatacgct tgataagtag cttctgtgaa cggatagttc ttttgctaaa
     1501 tcttgaattg taagtgattg aggatagtgg ctatcaatta atcgtttgca ttcaagatag
     1561 agttggtggg ttgatgaaat attctttttt ttctgattgg gagcaatagt tcccagatga
     1621 aacatcagtt catgaagttg tcccatgata tggagttgag ctaattcact tgattttgta
     1681 atctgagcga agcggacaat gtctgagatg agttttgcag tagtctgggt atgacaagtt
     1741 tcagattgga tgagatagga ttgatcagaa atttgagaaa gagcaaaata atcaggggat
     1801 ttccctccag tgattcctaa ccagtagtag gcccaaggtt ctttactatc tgcttgataa
     1861 aaggttagtt cctctggttt taatagaaag aaatctcctt cttttaaatc aacaatttta
     1921 cccttgtaat aaaattttcc ttgtccttta gtaatgtaat gtagaacgta tgtatcacga
     1981 atggctggac caaaagagta attaggtgtg cattcctcat atccataaaa gcttagggca
     2041 aggtcgattg ttccagtctg gtattctgaa aaaactaaca tgtgctacct cctacctaac
     2101 attttaccat attcttgaga catttttcta ttttggaaag cgatttcagg tgataaaata
     2161 taatcaataa agtgatgagg tgaagtaaat gggagttagg atagagaata atctatttta
     2221 tgttgagagt aaaaatctaa gtttgattat tgaaaatcga aatggctact tacttttgaa
     2281 acatttagga aagactatta agaactataa aggttccaat agtgtttatg aacgagacca
     2341 tgccttttca ggaaatccaa cggctactaa tcgaaccttt agtttagata ctcagcgaca
     2401 gatttttgga caacatggct taggagattt taggaaacca actatacagg ttcagcatag
     2461 tgtaactgaa gtaacagact ttcgatttgt agaagcaaag attttaaaag gtcagaatgg
     2521 tccacagggc ttaccttctc cacatagcat ggacgataca gagactcttg tcttaatgtt
     2581 agaagattct aaggctcaac ttagtctgac tttgtattat actactttta ataatgatgc
     2641 gactattact agctacagta aattagataa taatagtaat caggaagttg tcatccataa
     2701 agatttttct tttatggctg attttccagc tgcagattac gaaatagcaa ctctgcaggg
     2761 tgcttatgct cgtgaaaaga ctgttagacg tcaacaggta gaacaaggaa tcttttcgat
     2821 tagttcaaac cgaggtgctt ctggtcatgc tcaaacacca gctcttctac tatgcgaaca
     2881 aggagtcaca gaggatgctg ggaatgtgtt tgctattcaa ctaatgtata gtggcaactt
     2941 tgaagctttt gttcaaaaaa atcaattgaa tgaagttcgg gtggctattg gcattaatcc
     3001 agaaaacttt tcttggaagt tagcccctga ggaatacttt gaaacaccgg tagctttagt
     3061 gactcattca gatcagggat taactggtat tagtcatgaa agtcagaatt ttgtactgaa
     3121 gcacattatt ctaagtgaat tttctaaaaa agaacgtcca attctaatca ataactggga
     3181 agctacttac tttgactttc agagagaaaa actgttagag ttagcagatg aagctaagaa
     3241 agttggcatt gaactttttg tattagatga tggttggttt ggcaatcgtt ttgatgataa
     3301 tcgtgcttta ggtgattggg ttgttaatga ggaaaaactg ggtggaagtc tagaaagtct
     3361 gatttcagct atccatgaaa gaggtttgca gtttggactt tggttagaac ccgaaatgat
     3421 ttctgtagat agtgatttgt atcgtcaaca ccctgactgg gctattcagg ttcctgacta
     3481 tgagcatact tattctcgga atcaattagt acttaatctt gccaatcctc aggtagtaga
     3541 atacttgaaa agtgtcttag atcaactcct atcttatcat gagattgatt acattaaatg
     3601 ggatatgaac cgcaatatca ctaagctagg gaatggatta acttatctag agacacagat
     3661 gcaatctcat cagtacatgc tggggcttta tgaactcgtt tcttatctga cagagaagca
     3721 cagccatatt ctctttgagt cctgctctgg tggtggtgga cgaaatgatc ttggtatgat
     3781 acgctatttc ccacaagtct gggctagtga taatactgat gccattgcac gtttaccaat
     3841 tcaatacggt tcatcctatt tctatccaac catttctatg ggggctcatg tgtcagcagt
     3901 accgaatcat cagatgggac gaatgacacc attagaaaca cgtggccatg tagcaatgat
     3961 gggaaatttg ggctatgagc ttgatttgac aaatttatca gatgaagaga aagctacgat
     4021 tgctaatcag gtgaacttgt ataaagaatt acgaccagta gttcagttag gacagcagta
     4081 tagactaatt aatcctgata ctgcatccaa tgaagcagct gtacaattta attacggaaa
     4141 tcaaacgatt gtaacctacg ttcgcgtttt atctgttgta gagaccatgg aaacaacttt
     4201 aaaattaaaa gatttggatg aagagggact atataaatta caggaaaatg gcgaagttta
     4261 ctcaggtgca gaactaatgt atgcgggctt aactgttatc ttatcccaag gagatttttt
     4321 gagtagacag tatattttta gaaaactatg atatgtactg accccaaaag ttagatttat
     4381 tctatctaac ttttgaagtg cagtttgata agggtgtata aatttataaa ggaggctttc
     4441 taatggaatg gtataaaaaa atcggacttc ttgcaactac aggtttagct ttgtttgggc
     4501 tcggtgcttg ctccaactat ggtaaatctg cggatgacac agtgaccatc gagtatttca
     4561 accagaaaaa agaaatgacc aaaaccttgg aagaaatcac tcgtgatttt gagaaggaaa
     4621 accctaagat aaaggtcaaa gtcgtcaatg taccaaatgc tggtgaagta ttgaagacac
     4681 gcgttctcgc aggagatgtg cctgatgtgg tcaatattta cccacagtcc atcgaactgc
     4741 aagaatgggc aaaagcaggt gtctttgaag atttgagtaa caaagactac ctgaaacgcg
     4801 tgaaaaatgg ctacgctgaa aaatatgctg taaacgaaaa agtttacaac gttcctttta
     4861 cagctaatgc ttatggaatt tactacaaca aagataaatt cgaagaactg ggcttgaagg
     4921 ttcctgaaac ctgggatgaa tttgaacagt tagtcaaaga tatcgttgct aaaggacaaa
     4981 caccatttgg aattgcaggt gcagatgctt ggacactcaa tggttacaat caattagcct
     5041 ttgcgacagc aacaggtgga ggaaaagaag caaatcaata ccttcgttat tctcaaccaa
     5101 atgctattaa attgtcggat ccgattatga aagatgatat caaggtcatg gacatccttc
     5161 gcattaatgg ctctaagcaa aagaactggg aaggtgctgg ctataccgat gttatcggag
     5221 ccttcgcacg tggggatgtc ctcatgacac caaatgggtc ttgggcgatc acagcgatta
     5281 atgaacaaaa accgaacttt aagattggaa ccttcatgat tccaggaaaa gaaaaaggac
     5341 aaagcttaac cgttggtgcg ggagacttgg catggtctat ctcagccacc accaaacatc
     5401 caaaagaagc caatgccttt gtggaatata tgacccgttc agaagtcatg caaaaatact
     5461 acgatgtgga cggatctcca acagcgatcg aaggggtcaa acaagcagga gaagattcac
     5521 cgcttgctgg tatgaccgaa tatgccttta cggatcgtca cttggtctgg ttgcaacaat
     5581 actggaccag tgaagcagac ttccatacct tgaccatgaa ctatgtcttg accggtgata
     5641 aacaaggcat ggtcaatgat ttgaatgcct tctttaaccc gatgaaagcg gatgtggatt
     5701 aggagtagag agactatgaa aaaagtatta caaaaatatt gggcatgggc ttttgtggtc
     5761 atccccctct tgttacaagc aattttcttc tatgtgccga tgtttcaagg agccttttac
     5821 agttttacca actggacagg attgacttac aactacaaat ttgtcggctt aaacaacttt
     5881 aagctcctct tcatggatcc aaaattcatg aatgcgattg gctttaccgc aatcattacg
     5941 attgccatgg tggttggtga gattgcactc gggatcttca ttgcgcgtgt cttgaactct
     6001 aaaatcaaag gccaaacctt cttccgtgct tggttcttct tcccagctgt tttatctggt
     6061 ttgacagtgg ctttgatctt caagcaagtc ttcaactacg gtcttccagc gattgggaat
     6121 gcccttcata ttgaatttct ccaaaccagt cttttaggga ctaagtgggg agcaatcttt
     6181 gcggctgtct ttgtccttct ttggcaaggg gtggctatgc ccatcatcat cttcctagct
     6241 ggtttgcaat ctattccaac tgagattaca gaggcagcaa ggattgatgg tgcgactagc
     6301 aagcaagttt tctggaacat tgaattgcct tacttgctac caagtgtctc tatagtcttt
     6361 atcctagccc taaaaggtgg gctgactgcc tttgaccaag tctttgccat gaccggtggt
     6421 ggtccaaaca atgccacaac ctcacttggg ctcttggttt ataactatgc ctttaaaaac
     6481 aaccaattcg gttatgccaa tgccattgcc gtaaacttgt tcttcttaat tgtagtgatt
     6541 tcgatcatcc aattgagagt atctaagaaa tttgaaattt aagaggagaa gcatgatgaa
     6601 acaagatgaa agaaaagccc tgattggcaa atacattcta ttgattctag gatcggttct
     6661 gattttagtg ccgctccttg ctaccctctt tagttccttc aaatccacta aggatattgt
     6721 agataatttc tttggctttc caaccaactt cacatgggac aactttagcc gtctcttagc
     6781 tgatgggatt ggaggctatt attggaactc tgtcgtcatc actgtcttgt ctttacttgc
     6841 agtaatgatc tttatcccta tggcagccta ctccatcgct cgcaatatga gtaaaagaaa
     6901 agcctttacc atcatgtata ccctcttaat cctcggaatc ttcgtacctt tccaagtcat
     6961 catgattccg attacggtta tgatgagtaa actcggtttg gctaatacct ttggtttgat
     7021 cttgctctac ttgacctatg cgattccaca gaccctcttt ctctatgttg gctatatcaa
     7081 aatctcgatt ccagaaagtc tggatgaagc agcagagatc gatggggcta atcaatttac
     7141 aacctatttc cgcatcatct tcccaatgat gaaaccgatg catgcgacaa ccatgatcat
     7201 caatgccctt tggttctgga atgacttcat gttgccactc cttgtcttga accgggattc
     7261 caaaatgtgg actctgcctt tgttccaata caactacgca ggccaatatt tcaacgacta
     7321 cggaccaagc tttgcctctt acgtggtcgg cattatcagt atcaccattg tctatctctt
     7381 cttccaacgc catatcatcg caggaataag caacggggca gtgaagtaat actcaatgaa
     7441 aatcaaagag caaactagga agctagccgc aggttgctca aaacactgtt ttgaggttgt
     7501 ggatgaaact gacgaagtca gtaaccatat ctacggtaag gcgacactga cgtggtttga
     7561 agagattttc gaagagtata acatgaattt gatttacgaa gccagatcat atgagacttg
     7621 gcttcaatta gaaaaaggag agtaatgatg ccaattcaaa ataaaaccat gttgattacc
     7681 tattctgata gccttggaaa taatcttaaa gacttatatg ataatttgga agagcatttt
     7741 ggagatgcta ttggaggagt tcacctttta ccatttttcc catcaacagg tgatcgtgga
     7801 tttgcgccag ttgactacga cgaagtggac tcagcttttg gtgattggga ggatgttaag
     7861 cgtttaggtg agaaatatta tcttatgttt gattttatga ttaatcatat ttctcgtcaa
     7921 tccaagtatt ataaggacta tcaagaaaaa catgaagcca gtgaatttaa agatctcttt
     7981 ttaaactggg ataagttttg gccagaaaac cgtccgacac agtctgatgt agatttaatt
     8041 tacaagcgta aggatcgtgc accaaagcaa gagattgtgt ttgaagatgg ttcagtggaa
     8101 catttgtgga atacctttgg tgaggagcag attgatcttg atgtgaccaa agaagtaact
     8161 atggaattta tccgtaagac cattcagcac ttggcaagta atgggtgtga tttgattcgt
     8221 ctagatgcct ttgcttatgc agtgaagaaa ttggatacta atgatttctt tgtggaacca
     8281 gatatttggg atttattgga caaagttcga gatatcgctg ctgagtatgg gacagagatt
     8341 ttacctgaga ttcatgaaca ctattcgatt cagtttaaaa tagcagacca tgattactat
     8401 gtttatgatt ttactcttcc aatggtgaca ctttatactc tttacagttc cagaacagag
     8461 cgtttggcta agtggttgaa gatgagcccg atgaagcaat ttacgacgct agatacccat
     8521 gatgggattg gagtagtaga tgtcaaggat atcctgaccg atgaggagat tgactatgct
     8581 tcaaatgaac tctataaggt tggagccaat gtcaaacgta agtactctag tgccgagtat
     8641 aacaacttag atatctacca aatcaattca acctactatt cagcgcttgg agatgatgat
     8701 gtcaagtatt ttctcgctcg tctaattcaa gcttttgccc caggtattcc tcaggtttac
     8761 tatgtgggtc tattagcagg caagaatgac ttgaaattat tagaagaaac taaagaaggt
     8821 cgaaatatta atcgtcatta ctatagcaac gaggaaatag caagagaagt gcaacgacct
     8881 gttgtgaagg cccttctcaa tctattttct ttccgtaacc gttcagaagc ctttgatcta
     8941 gaagggacta ctgagataga gacaccaaca gctcacagca ttgtaatcaa acgtcaaaat
     9001 aaagataagt ccgtaacagc agtagcagaa attgatttgc aaaatcagac ttatcgggta
     9061 attgagaatg gagttgaagt atcattttga agccttgata tggtggataa aatagggttt
     9121 ttattttgga aaacgtttcc tttgttttca aattgctaaa aaagtggtac aatataggat
     9181 agcttactat tatctgaatc agctgatttg gagagaaagg attcattttg aaatcaatag
     9241 gctttattga aaagctgaag gggttgtcta gtaaagagct gattttattg ggaattatcc
     9301 taagtatctt tttacccttt tatctttttg tagttgtact ctgtttatat attatcagtt
     9361 tgatttttac aggagacatg aaaagtattc ttcagaaaat gggggagcat ccgatgctgc
     9421 ttctttttct tagctatagt actgttatat ccattcttgc acaaaattgg atgggtcttg
     9481 tggcttcagt aggaatgttt ctatttacta ttttcttttt gcactatcag tcgattttat
     9541 cccataaatt ctttcgattg attttgcagt tcgtcttgtt tggtagtgtc ttgtcagctg
     9601 cttttgccag tttagaacat ttccaaattg tgaagaaatt taactatgct tttctttcac
     9661 ccaatatgca ggtgtggcat cagaaccggg cagaagtgac cttctttaat cctaattatt
     9721 atggaattat ttgttgtttc tgtattatga ttgctttcta tctgtttaca acgaccaagt
     9781 tgaattggtt gaaagtattc tgtgtgattg caggctttgt taatctcttt ggtttgaact
     9841 ttactcaaaa tcgaactgcc tttcctgcta ttatcgctgg agcaattatc tatctcttta
     9901 cgactattaa aaactggaag gccttttggc ttagtattgg ggtcttcgcg attggtttga
     9961 gtttcctctt ttctagtgat ttgggagttc gaatgggtac tttagactct tctatggaag
    10021 aacgcatttc tatctgggat gctgggatgg ccttgtttaa gcaaaatcct ttttggggtg
    10081 aagggccatt gacctatatg cactcttatc ctcggataca tgctccttat catgaacatg
    10141 cccacagtct ttatattgat acgattctga gttacggaat tgtgggtacc attttattag
    10201 ttttgtcttc tgttgctcct gttcgcttga tgatggatat gagtcaggag tcggggaaac
    10261 gtccgattat cggcctttat ctatctttcc ttacagtggt tgctgtgcac ggaatttttg
    10321 acttggctct cttctggatt cagtcaggct ttattttctt gctagttatg tgcagtattc
    10381 cattggagca tcgaatgttg gtatcggaca tgacggatta agttttataa gtttgaaatc
    10441 ttctaccttg ggtaggagat ttttttatac gatgggcatg tcgtgcatct gaggtgtaag
    10501 tcctctgtag ggatccacta ccggtgaata caatagcgct ccccaagcct gactatcgtg
    10561 aggtagcgga ttaaaatggt ctggggatag atcgttttaa gtctgacgca ggaaataaga
    10621 attgtcagag aaagcaatag tgaaatcgta ggctatgaat agaaacgtga tagcgaggag
    10681 catatagtgg ataaggtagc gagaaatttt aaagtataaa agatagtctt aatctatata
    10741 tgtaaatcac aaaagtaatt gaattcggaa taaggttggt gtgaaaagac atagtaaact
    10801 gaatcttgaa tactagaatg atacttctac aatattgtta taatttaatt tgaattccaa
    10861 aatcacattg ttccgtccgt atttcatttt actgtatgtc ttcctaaact ccaaagtttc
    10921 tgcgtcaaat ttcctatttt cactgtagtc tttgacactt cgaacgacaa tttgaatcat
    10981 atattcaaaa aaaaatgaaa aatttgtgcc aacaagccta aatattctga aaatttgttt
    11041 gatttttaat ggataatgtg atataatggt tgtcaatcta taattcacat aaacagagga
    11101 gtagaaaatg aaaaaaaatc gtgtatttgc tacagcaggt cttgttttat tagcagcagg
    11161 tgtacttgca gcatgcagtt cttcaaaatc atctgattca tcagccccta aagcttatgg
    11221 ctatgtttat acagcagacc cagaaacctt ggactacctg atttcaagta aaaatagtac
    11281 aacagtagtg acttcaaatg ggattgatgg tttattcact aacgataatt acggtaatct
    11341 tgctcctgca gttgcagagg attgggaagt ctctaaggat ggtttgacct acacttataa
    11401 gattcgtaaa ggggttaaat ggtttacctc tgatggagaa gaatatgcag aggtgacggc
    11461 taaagatttc gtgaacggtt taaaacacgc agcagataaa aaatcagaag ctatgtattt
    11521 agctgaaaat tcggttaaag gcttggcaga ttatctatca ggaacttcaa cagatttttc
    11581 aacagttggt gtcaaggcgg ttgatgatta tacgttacaa tacactttga accagcctga
    11641 accgttctgg aactctaagt tgacctattc tattttctgg cctctgaatg aagaattcga
    11701 aacatcaaaa ggaagcgatt ttgctaaacc aacagatccg acatccttgc tttataatgg
    11761 tccattcttg ttgaaagggt tgactgcaaa atcttctgta gagtttgtaa aaaatgagca
    11821 atattgggat aaagaaaatg tccacctaga tactatcaat ctagcttact atgatggatc
    11881 agatcaggag tcgctagagc gtaacttcac tagtggagct tatagttatg cccgtcttta
    11941 ccctaccagc tccaactatt ctaaggttgc agaagaatac aaggacaata tctattacac
    12001 acaatcaggc tctgggattg ctggtctggg tgtgaatatt gatcgccaaa gttacaacta
    12061 tacttctaaa actacagatt cagagaaagt agctactaag aaggcattgc ttaacaaaga
    12121 tttccgtcaa gccttgaatt ttgctcttga tcgctcagct tactcagctc aaatcaatgg
    12181 taaagatgga gcagctttag cagttcgtaa tttatttgta aaaccagact ttgtttcagc
    12241 tggtgagaag acctttggtg atttagtcgc tgctcaactt cctgcttatg gtgatgagtg
    12301 gaaaggtgtg aatttagctg atgggcagga tggtttattc aatgctgaca aggccaaggc
    12361 agagtttgcg aaagctaaga aagctttaga agcagacggc gttcagtttc ctattcatct
    12421 ggacgttcca gtagaccaag catcaaaaaa ctacatatct cgtattcagt cctttaaaca
    12481 atctgtagaa acagttcttg gtgttgaaaa tgtcgttgtt gatattcaac aaatgacaag
    12541 tgatgaattc cttaatatta cttactatgc tgccaatgct tcatctgagg attgggatgt
    12601 atcgggagga gtttcatggg ggccagacta tcaagaccca tctacttacc tggatatttt
    12661 aaaaacaact agcagtgaaa ctacaaaaac atatttagga tttgataatc caaatagccc
    12721 ttcagtagtt caagttggtt tgaaagaata cgataaatta gttgatgaag ctgccaaaga
    12781 gacaagcgac ttgaatgtcc gttatgaaaa atatgcagcg gctcaagcat ggttgacaga
    12841 tagttcactc tttattcctg ctatggcttc ttctggtgca gcaccagtgc tttcacgaat
    12901 tgttccattt actggagctt ctgcgcaaac aggctctaag gggtcagatg tttacttcaa
    12961 atatttgaaa ttacaagata aagtggtgac taaggaagag tatgaaaaag ctcgtgaaaa
    13021 atggttgaaa gaaaaagctg aatcaaatga gaaagctcaa aaagaattgg caagtcatgt
    13081 gaagtaaata atttctaata gaactttctc tccatgagga gaaggttctt ttgggatttt
    13141 taaaggaaat aatatgaaaa aatatatttt tatgcgtgtt ttgcggtcat tggtttcgat
    13201 tttcttagta acgactttga cctacacgat tatctatacc ttggttcctc gaaaattgat
    13261 tttcaagcag gatcctaact ataataaaat tgcaacaacg gctgataaac gtgataacta
    13321 tgaaaatact gtgtttgagc gtatgggcta cattgagtat tacgatacta aagagttgca
    13381 agaaaaggca agtagcatgg attcttctgt aacagtagaa gcaaatgcga ccaataaagc
    13441 tatttatgaa aagtacatca atcaattagg tcatggttgg actttgggag aatttactga
    13501 aagtggtcaa ttctatgcta ctcgtgaaat tccaattttt gaacgtgttt ttcacttcta
    13561 tgctaacttg attgacattg accatacaaa taaaatccaa gaccctgaaa atccagactt
    13621 gaaacgctac cttcgttttg aaaatgatcc agctatcgga tggtcattgg tcggttcagg
    13681 aactaaacat aaatatctct tgtactttaa cagtcagttc ccatttgttc atcaaaactt
    13741 tgtgaacttg aatttaggtg actcttaccc aacctatgct aatacaccag ttcttcaggt
    13801 tattactcaa ggtcaaggac aaaccaaaac tgcccaagtt cagttcccaa caggtaagaa
    13861 aacgtcttct gtaaatattt actcaagaac ctacaagtca cctagtcagg ctgactctcg
    13921 tgaagtagct agctatggga aagatgatcc ttatacagcg actgaaagta attaccaata
    13981 tccatctatg attgtcagct ctgctattac tggtttgatt ggtttggttc ttgcctatgc
    14041 tcttgccgtg ccacttggtt cagccatggc tcgtttcaag aacacttgga ttgatagcct
    14101 ctcaacaggg gctttgacct tcttgcttgc tcttccaacg attgccttgg tttacatcgt
    14161 tcgattgatt ggatcatcta ttgcccttcc agattcattc cctatcttgg gagctggaga
    14221 ttggcgttct tacgttttac cagcagtcat ccttggtttg ttgggtgctc ctggtacagc
    14281 catttggatt cgtcgttaca tgattgactt gcaatctcaa gactttgttc gtttcgctcg
    14341 tgcaaaaggt ttgtctgaaa aagaaatttc aaacaaacac atctttaaaa atgccatggt
    14401 tccgctggtt tcaggaattc ctggtgccat cattggggtt atcggtggtg caacccttac
    14461 tgaaacagtc ttcgccttcc caggtatggg taaaatgttg attgactctg taaaagcatc
    14521 taataactct atggtcgttg gtcttgtctt catctttaca tgtatttcta tcttctcacg
    14581 tcttttggga gatatttgga tgactattat tgacccacgt attaaattga ctgagaaagg
    14641 aggcaaataa tgtctacaat cgataaagaa aaatttcagt ttgtaaaacg tgacgatttt
    14701 gcctctgaaa ctattgatgc gccagcatat tcttactgga aatcagtgtt taaacaattt
    14761 atgaagaaaa aatcaactgt agtcatgttg ggaatcttgg tagccatcat tttgataagt
    14821 ttcatctacc caatgttttc taagtttgat ttcaatgatg tcagcaaggt aaacgacttt
    14881 agtattcgtt atatcaagcc aaatgcggag cattggttcg gtactgacag taacggtaaa
    14941 tcgctctttg acggtgtctg gttcggagct cgtaactcca tcctcatttc tgtgattgcg
    15001 acagtgatta acttggttat cggtgttttt gtcggtggta tttggggtat ttcaaaatca
    15061 gttgaccgtg tcatgatgga agtttacaac gtcatctcaa acatcccacc tcttttgatt
    15121 gttattgtct tgacttactc aatcggagct ggattctgga atctgatttt tgccatgagc
    15181 gtaacaacat ggattggtat cgccttcatg atccgtgtgc aaatcttgcg ctatcgtgac
    15241 ttggaataca acttggcatc acgtactttg ggaacaccaa ccttgaagat tgttgccaaa
    15301 aatatcatgc ctcaattggt atctgttatt gtgacaacca tgactcaaat gcttccaagc
    15361 tttatctcat acgaagcctt cttgtctttc ttcggtcttg gattaccgat tacagtgcca
    15421 agtttgggtc gtttgatttc ggattattca caaaacgtaa caaccaatgc ttacttgttc
    15481 tggattccat tgacaaccct tgtcttggta tccttgtccc ttttcgtagt tggtcaaaac
    15541 ttagcggatg ctagtgatcc acgtacacat agataggagt agaaatgaca aaagaaaaaa
    15601 atgtaatttt gactgctcgc gatattgtcg tggaatttga cgttcgtgac aaagtattga
    15661 cagccattcg cggcgtttcc cttgaactcg ttgaaggaga agtattagcc ttggtaggtg
    15721 agtcaggatc aggtaaatct gttttgacaa agaccttcac aggtatgctc gaagaaaatg
    15781 gtcgcattgc ccaaggtagt attgactacc gtggtcagga tttgacagct ttatcttctc
    15841 acaaggattg ggaacaaatt cgtggtgcta agattgcgac tatcttccag gacccaatga
    15901 ctagtttgga ccccattaaa acaattggta gtcagattac agaagttatt gtaaaacacc
    15961 aaggaaaaac agctaaagaa gcgaaagaat tggccattga ctacatgaat aaggttggca
    16021 ttccagacgc agatagacgt tttaatgaat acccattcca atattctgga ggaatgcgtc
    16081 aacgtatcgt tattgctatt gcccttgcct gccgacctga tgtcttgatc tgtgatgagc
    16141 caacaactgc cttggatgta actattcaag ctcagattat tgatttgcta aaatctttac
    16201 aaaacgagta tcatttcaca acaatcttta ttacccacga ccttggtgtg gtggcaagta
    16261 ttgcggataa ggtagcggtt atgtatgcag gagaaatcgt tgagtatgga acggttgagg
    16321 aagtcttcta tgaccctcgc catccatata catggagtct cttgtctagc ttgcctcagc
    16381 ttgctgatga taaaggggat ctttactcaa tcccaggaac acctccgtca ctttatactg
    16441 acctgaaagg ggatgctttt gccttgcgtt ctgactacgc aatgcagatt gacttcgaac
    16501 aaaaagctcc tcaattctca gtatcagaga cacattgggc taaaacttgg cttcttcatg
    16561 aggatgctcc aaaagtagaa aaaccagctg tgattgcaaa tctccatgat aagattcgtg
    16621 aaaaaatggg atttgcccat ctggctgact aggaggaagg aaatgtctga aaaattagta
    16681 gaaatcaaag atttagaaat ttccttcggt gaaggaagta agaagtttgt cgcggttaaa
    16741 aatgctaact tctttatcaa caagggagaa actttctcgc ttgtaggtga gtccggtagt
    16801 gggaaaacaa ctattggtcg tgctatcatc ggtctaaatg atacaagtaa tggagatatc
    16861 atttttgatg gtcaaaagat taatggtaag aaatcgcgtg aacaagctgc ggaattgatt
    16921 cgtcgaatcc agatgatttt ccaagaccct gctgcaagtt tgaatgaacg tgcgactgtt
    16981 gattatatta tttctgaagg tctttacaat caccgtttat ttaaggatga agaagaacgt
    17041 aaagagaaag ttcaaaatat tatccgtgaa gtaggtcttc ttgctgagca cttgactcgt
    17101 taccctcatg aattctcagg cggtcaacgt caacgtatcg gtattgcccg tgccttggtc
    17161 atgcaaccag actttgttat tgcagatgag ccaatttcag ccttggacgt ttctgtacgt
    17221 gcccaagtct tgaacttgct caaaaaattc caaaaagagc tcggcctgac ctatctcttc
    17281 atcgcccatg acttgtcggt tgttcgcttt atttcagatc gtatcgcagt tatttacaag
    17341 ggtgttattg tagaggttgc agaaacagaa gaattgttta acaatccaat tcacccatat
    17401 actcaagcct tgctttcagc ggtaccaatc ccagatccaa tcttggaacg taagaaggtc
    17461 ttgaaggttt acgacccaag tcaacacgac tatgagactg ataagccatc tatggtagaa
    17521 atccgtccag gtcactatgt ttgggcgaac caagccgaat tggcacgtta tcaaaaagga
    17581 ctaaactaat aatggtttta taatttccat gtcaattttt atgggaatta taaaactttt
    17641 ttgttggact gatttgaaaa actttgaaag cttcctgaaa ga
//
LOCUS       DAVBDR010000043        17282 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.043, whole genome shotgun sequence.
ACCESSION   DAVBDR010000043 DAVBDR010000000
VERSION     DAVBDR010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17282)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17282)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17282
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.043"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            complement(<1..692)
                     /locus_tag="VQ540_001502"
     CDS             complement(<1..692)
                     /locus_tag="VQ540_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HET2545286.1"
                     /translation="MNIILIAKPLRENTNTKANALNNGWARSGSEEFKKFSHFVGVDK
                     GIVRTNVLTGKKLSDKIRKEVGSGDSKLGKGGYFSTGDVLLGKDVVSYTVQVFSENNE
                     RVGVNTQSYRVQYNLPILADFSVIQDTVEPSRTVVEKIIPKLNIPEEEKGKITEEIKK
                     KKKTSELAELISENVKVRYVDEQGRLLSLKNDTGIGEKESDGTYITNKKQLIGTSYNV
                     TDKKLSSMTTTDG"
     gene            complement(803..1057)
                     /locus_tag="VQ540_001503"
     CDS             complement(803..1057)
                     /locus_tag="VQ540_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2545287.1"
                     /translation="MLNVDQDFMSISKSNKSGSDWKKTFTVRITNRLANDLNNVLKQV
                     DKDTPNTPTWLNSAASKAKDDDRVYKLLKTLIPGENYLSC"
     gene            complement(1415..1948)
                     /locus_tag="VQ540_001504"
     CDS             complement(1415..1948)
                     /locus_tag="VQ540_001504"
                     /inference="COORDINATES: protein motif:HMM:NF024751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
                     /protein_id="HET2545288.1"
                     /translation="MTIFKEQESEKVAEFLDILDNLKDLPIVYIDETGIDRYLYRPYA
                     GAPRGEKVYEKISGRRFERTSIVAGQVDGEFIAPMIYKKSMTSDFFVEWFKTQLLPAL
                     KTPHVIVMGNASFHPKNILDELCIQDKHFFLPLPPYSPDLNPIEQAWAILKKKVTDLL
                     REVPTIFECLECFFKTR"
     gene            complement(1935..2261)
                     /locus_tag="VQ540_001505"
     CDS             complement(1935..2261)
                     /locus_tag="VQ540_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2545289.1"
                     /translation="MAYNTDFKQGALDSIKGGHRHVEAAKVFWCWRQNSLHVGKERRE
                     QRNLERKKRVVKKRKIPLEELKAFVEAHPDAFLREIAAHFDCAVPSVWAALKQIKVTL
                     KKDDDL"
     gene            2495..4213
                     /locus_tag="VQ540_001506"
     CDS             2495..4213
                     /locus_tag="VQ540_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HET2545290.1"
                     /translation="MSYQENYQKWVDFVELPDYLRQDLENMDEKTKEDAFYTNLEFGT
                     AGMRGLVGAGTNRINIYVVRQATEGLARLIESKGGNEKERGVAIAYDSRHFSPEFAFE
                     SAAVLAKHGIKSYVFESLRPTPELSFAVRHLNCFAGIMVTASHNPAPFNGYKVYGEDG
                     GQMPPHDADALTTYIRAIENPFAVEVADVETEKASGLIEVIGEAVDVEYLKEVKDVNI
                     NPALIEEFGKDMKIVYTPLHGTGEMLARRALAQAGFDSVQVVEAQATADPDFSTVTSP
                     NPESQAAFALAEELGRQVGADVLVATDPDADRVGVEVLQKDGSYLNLSGNQIGAIMAK
                     YILEAHKNAGTLPENAALCKSIVSTDLVTKIAESYGATMFNVLTGFKFIAEKIQEFEE
                     KHNHTYMMGFEESFGYLIKPFVRDKDAIQAVLVVAELAAYYRSRGLTLADGIEEIYKE
                     YGYYAEKTISVTLSGVDGAEQIKAIMAKFRNNAPKEWNATAITVVEDFKAQTATVADG
                     TVTNLTTPPSDVLKYTLADGSWIAVRPSGTEPKIKFYIAVVGETNEESQAKIANIEAE
                     INAFVK"
     gene            4324..4671
                     /locus_tag="VQ540_001507"
     CDS             4324..4671
                     /locus_tag="VQ540_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HET2545291.1"
                     /translation="MEQFLDNIKDLEVTTVVRAQEALDKKETATFFIGRKTCPYCRKF
                     AGTLSGVVAETKAHIYFINSEEPSQLNDLQAFRSRYGIPTVPGFVHITDGQINVRCDS
                     SMSAQEIKDFAGL"
     gene            complement(4949..5785)
                     /locus_tag="VQ540_001508"
     CDS             complement(4949..5785)
                     /locus_tag="VQ540_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HET2545292.1"
                     /translation="MKKWMLVLVSLMTALFLVACGKNSSETSGDNWSKYQSNKSITIG
                     FDSTFVPMGFAQKDGSYAGFDIDLATAVFEKYGITVNWQPIDWDLKEAELTKGTIDLI
                     WNGYSATDERREKVAFSNSYMKNEQVLVTKKSSGITTAKDMTGKTLGAQAGSSGYADF
                     EANPEILKNIVANKEANQYQTFNEALIDLKNDRIDGLLIDRVYANYYLEAEGVLNDYN
                     VFTVGLETEAFAVGARKEDTTLVKKINEAFSSLYKDGKFQEISQKWFGEDVATKEVKE
                     GQ"
     gene            complement(5798..6427)
                     /locus_tag="VQ540_001509"
     CDS             complement(5798..6427)
                     /locus_tag="VQ540_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000891751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HET2545293.1"
                     /translation="MLELRNINKVFGDKQILSNFSLSIPEKQILAIVGPSGGGKTTLL
                     RMLAGLETIDSGQIFYNGQPLELDELQKRNLLGFVFQDFQLFPHLSVLDNLTLSPVKT
                     MGMKQEEAEKKASGLLEQLGLGGHAEAYPFSLSGGQKQRVALARAMMIDPEIIGYDEP
                     TSALDPELRLEVEKLILQNRELGMTQIVVTHDLQFAENIADVLLKVEPK"
     gene            complement(6437..7078)
                     /locus_tag="VQ540_001510"
     CDS             complement(6437..7078)
                     /locus_tag="VQ540_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET2545294.1"
                     /translation="MSYLFEILPSLLNGASTTVQVFALVLLFSIPLGVLIAFALQVHW
                     KPLHYLINIYIWVMRGTPLLLQLIFIYYVLPSIGIRLDRLPAAIIAFVLNYAAYFAEI
                     FRGGIDTIPRGQYEAAKVLKFSPFDRVRYIILPQVTKIVLPSVFNEVMSLVKDTSLVY
                     ALGISDLILASRTAANRDASLVPMFLAGAIYLILIGIVTIISKKVEKKYSYYR"
     gene            complement(7224..8453)
                     /locus_tag="VQ540_001511"
     CDS             complement(7224..8453)
                     /locus_tag="VQ540_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HET2545295.1"
                     /translation="MNNSQQMLQALEEQDLTKAEHYFAKALENDSSDLLYELATYLEG
                     IGFYPQAKEIYLKIVEDFPEVHLNLAAIASEDGQIEEAFTYLEEIQADSDWYVSSLAL
                     KADLYQLEGLTDVAREKLLEALTYSEDSLLILGLAELDSELENYQAAIQAYAQLDNRS
                     IYEQTGISTYQRIGFAYAQLGKFETATEFLEKALELEYDDLTAFELASLYFDQEEYQK
                     ATLYFKQLDTISPDFEGYEYGYSQALHKEHQVQEALRIAKQGLEKNPFETRLLLAASQ
                     FSYELHDASGAENYLLTAKEDAEDTEEILLRLATIYLEQERYEDILDLQSEESENLLT
                     KWMIARSYQEMDDLDTAYEHYQELIGDLKDNPEFLEHYIYLLRELGHFEEAKVHAHTY
                     LKLVPDDVQMQELFERL"
     gene            complement(8443..9609)
                     /locus_tag="VQ540_001512"
     CDS             complement(8443..9609)
                     /locus_tag="VQ540_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HET2545296.1"
                     /translation="MEQKEKHFSLSWFFKWFLDNKAITVFLVTLLLGLNLFILSKISF
                     LFSPVLDFLAVVMLPVILSGLLYYLLNPIVDWMEKHKVNRVIAITIVFVIIALFIIWG
                     LAVAIPNLQRQVLTFARNVPVYLEDIDRIVNGLVAQHLPDDFRPQLEQVLTNFSSQAT
                     VLASKVSSQAVNWVSAFISGASQVIVALIIVPFMLFYLLRDGKGLRNYLTQFIPRKLK
                     EPVGQVLSDVNQQLSNYVRGQVTVAIIVAVMFIIFFKIIGLRYAVTLGVTAGILNLVP
                     YLGSFLAMLPALVLGLIAGPVMLLKVVIVFIVEQTIEGRFVSPLILGSQLNIHPINVL
                     FVLLTSGSMFGIWGVLLGIPVYASAKVVISAIFEWYKVVSGLYELEGEEVKSEQ"
     gene            9753..10766
                     /locus_tag="VQ540_001513"
     CDS             9753..10766
                     /locus_tag="VQ540_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HET2545297.1"
                     /translation="MKETVYFGTYTRRTSQGIYKADFDTETGQLSNLELFAAEPSPTY
                     LAFDQHQHLYTVGSQDDKGGIAAYQTDGTVLNHVVEEGAPHCYVAVDEKRDLVYAANY
                     HKGQVLVYKRQEDGSLLLSDMDQHSGQGPHENQASPHVHYTDLTPDHYLVTCDLGTDQ
                     VITYDLDQEGKLSKLYTYHSKPGAGSRHIIFHNHYKIAYLICELNSTIEVLIYDGVGE
                     FERMQVISTLPEAYEGFNGTAAIHLSKDGKYLYASNRGHDSIAVYTILADGSLELLEI
                     VPTHGQTPRDFDLTPDQKFLIVVHQDSDNATVFKRNCDNGRLAELSNDFHVPEAVCIR
                     FAP"
     gene            complement(10811..11230)
                     /locus_tag="VQ540_001514"
     CDS             complement(10811..11230)
                     /locus_tag="VQ540_001514"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HET2545298.1"
                     /translation="MAQLTVQIVTPDGLVYDHHASYVSVRTLDGEMGILPRHENMIAV
                     LAVDEVKVKRIDDKDQVNWIAVNGGVIEIANDMITIVADSAERARDIDISRAERAKLR
                     AERAIEEAQDKHLIDQERRAKIALQRAINRINVGNRL"
     gene            complement(11241..12647)
                     /gene="atpD"
                     /locus_tag="VQ540_001515"
     CDS             complement(11241..12647)
                     /gene="atpD"
                     /locus_tag="VQ540_001515"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HET2545299.1"
                     /translation="MSSGKIAQVIGPVVDVLFAAGEKLPEINNALVVYKNDERKTKIV
                     LEVALELGDGMVRTIAMESTDGLTRGMEVLDTGRPISVPVGKETLGRVFNVLGDTIDL
                     EAPFTEDAERQPIHKKAPTFDELSTSSEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFAGVGERTREGNDLYWEMKESGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSVTSIQAIYVPADDYTDPAPATAFAHLDSTTNLERKLVQ
                     LGIYPAVDPLASSSRALAPEIVGEEHYAVAAEVKRVLQRYHELQDIIAILGMDELSDE
                     EKTLVARARRIQFFLSQNFNVAEQFTGQPGSYVPVAETVRGFKEILDGKYDHLPEDAF
                     RGVGSIEDVIAKAEKMGF"
     gene            complement(12733..13611)
                     /locus_tag="VQ540_001516"
     CDS             complement(12733..13611)
                     /locus_tag="VQ540_001516"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002895995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HET2545300.1"
                     /translation="MAVSLNDIKTKIASTKNTSQITNAMQMVSAAKLGRSEEAARNFQ
                     VYAQKVRKLLTDILHGNGAGASTNPMLISRSVKKTGYIVITSDRGLVGGYNSSILKAV
                     MELKEEYHPDGKGFEMICIGGMGADFFKARGIQPLYELRGLADQPSFDQVRKIISKTV
                     EMYQNELFDELYVCYNHHVNTLTSQMRVEQMLPIVDLDPNEADEEYSLTFELETSREE
                     ILEQLLPQFAESMIYGAIIDAKTAENAAGMTAMQTATDNAKKVINDLTIQYNRARQAA
                     ITQEITEIVAGASALE"
     gene            complement(13627..15132)
                     /locus_tag="VQ540_001517"
     CDS             complement(13627..15132)
                     /locus_tag="VQ540_001517"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HET2545301.1"
                     /translation="MAINAQEISALIKQQIENFKPNFDVTETGVVTYIGDGIARAHGL
                     ENVMSGELLNFENGSYGMAQNLESTDVGIIILGDFTDIREGDTIRRTGKIMEVPVGES
                     LIGRVVDPLGRPVDGLGEIHTDKTRPVEAPAPGVMQRKSVSEPLQTGLKAIDALVPIG
                     RGQRELIIGDRQTGKTTIAIDTILNQKDQDMICIYVAIGQKESTVRTQVETLRQYGAL
                     DYTIVVTASASQPSPLLFLAPYTGVAMAEEFMYQGKHVLIVYDDLSKQAVAYRELSLL
                     LRRPPGREAFPGDVFYLHSRLLERSAKVSDELGGGSITALPFIETQAGDISAYIATNV
                     ISITDGQIFLGDGLFNAGIRPAIDAGSSVSRVGGSAQIKAMKKVAGTLRIDLASYREL
                     EAFTKFGSDLDAATQAKLNRGRRTVEVLKQPVHKPLPVEKQVTILYALIHGFLDTVPV
                     DDIVRFEEEFHAFFDAQHPEILETIRDTKDLPEEAVLDAAITEFLNQSSFQ"
     gene            complement(15147..15683)
                     /locus_tag="VQ540_001518"
     CDS             complement(15147..15683)
                     /locus_tag="VQ540_001518"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HET2545302.1"
                     /translation="MDKKTVKVIEKYSMPFVQLVLEKGEEDRIFSDLTQIKQVVEKTG
                     LPSFLKQVAVDESDKEKTIAFFQDSVSPLLQNFIQVLAYNHRANLFYDVLVDCLNRLE
                     KETNRFEVTITSAHPLTDEQKTRLLPLIEKKMSLKVRSVKEQIDESLIGGFVIFANHK
                     TIDVSIKQQLKVVKENLK"
     gene            complement(15683..16177)
                     /gene="atpF"
                     /locus_tag="VQ540_001519"
     CDS             complement(15683..16177)
                     /gene="atpF"
                     /locus_tag="VQ540_001519"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HET2545303.1"
                     /translation="MHVTVGELIGNFILITGSFILLLVLIKKFAWSNITGIFEERAEK
                     IASDIDRAEEARQKAEVLAQKREDELAGSRKEAKTIIENAKETAEQSKANILADAKLE
                     AGHLKEKANQEIAQNKVEALQSVKGEVADLTISLAGKIISQNLDSHAHKALIDQYIDQ
                     LGEA"
     gene            complement(16191..16907)
                     /gene="atpB"
                     /locus_tag="VQ540_001520"
     CDS             complement(16191..16907)
                     /gene="atpB"
                     /locus_tag="VQ540_001520"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HET2545304.1"
                     /translation="MEESINPIISIGPVIFNLTMLAMTLLIVGVIFVFIYWASRNMTL
                     KPKGKQNVLEYVYDFVIGFTEPNIGSRYMKDYSLFFLCLFLFMVIANNLGLMTKLQTI
                     DGTNWWSSPTANLQYDLTLSFLVILLTHIESVRRRGFKKSIKSFMSPVFVIPMNILEE
                     FTNFLSLALRIFGNIFAGEVMTSLLLLLSHQAIYWYPVAFGANLAWTAFSVFISCIQA
                     YVFTLLTSVYLGNKINIEEE"
     gene            complement(16942..17142)
                     /locus_tag="VQ540_001521"
     CDS             complement(16942..17142)
                     /locus_tag="VQ540_001521"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit C"
                     /protein_id="HET2545305.1"
                     /translation="MNLTFLGLCIACMGVSVGEGLLMNGLFKSVARQPDMLSEFRSLM
                     FLGVAFIEGTFFVTLVFSFIIK"
BASE COUNT         5222 a         3786 c         3096 g         5178 t
ORIGIN      
        1 ccgtcagtag tagtcatgct actgagtttt ttatctgtga cattgtagct ggtaccaatc
       61 agttgttttt tattggtaat gtaggttccg tcactttctt tttctccaat tccagtatca
      121 tttttcaatg atagcaaacg cccttgttca tcaacatagc gaactttcac attttctgag
      181 attagttctg ccaattctga ggtttttttc tttttcttga tttcttcggt tattttccct
      241 ttctcttctt cgggaatatt tagttttgga atgatttttt caacaacggt tcgtgatggt
      301 tccacagtat cttggatgac tgaaaagtca gctagaattg ggagattata ctgaacacgg
      361 taactttgag tgtttactcc tactctttca ttattctctg aaaatacttg tacggtataa
      421 gaaacaacat cttttcctaa tagaacatcc ccagtagaga aatagccgcc ttttcctagt
      481 ttgctatctc cagagcccac ttctttccta attttatcag atagtttttt accagtcagt
      541 acattcgttc gcacaatccc tttgtctacc cctacaaagt gggagaactt tttgaactct
      601 tcagaaccag atctagccca accattatta agggcatttg cttttgtatt tgtattctct
      661 ctcaaaggtt tggcgattag aattatattc atcggcactt agagttgctg ctatatctga
      721 ctcttgaata ccaacttcct tactaccatt tctagcggca gtatatgtgt atttatctgt
      781 ttctacttct agctgattat ccttaacatg ataggtaatt ttctcctggt ataagagtct
      841 tcagtagttt atatactctg tcatcatctt tagctttaga agcagctgag tttagccaag
      901 ttggggtatt aggagtatct ttatcaacct gtttcaagac attattcaag tcatttgcta
      961 gcctattggt tatcctcact gtgaaagttt tcttccagtc tgaaccactt ttattagact
     1021 tagatatgct catgaaatcc tggtcaacat tcaacacaat atcgccttgt tttttagcat
     1081 cttccgttgc ttctgcttca aattgatcat ggagtttttg ttgctctggt gtatagtttt
     1141 tttatttaca cgatttaatg tactattttt tattttagta ttaagaactc cattaatacg
     1201 atttttaaac tctgcttcaa aaaatccctt aatttgttgg tgcgcaagtt caacattcaa
     1261 acctttctta tacaagtctt cattctgata caagtcttca ttctgaacga tttcggctac
     1321 acggtgaatg gtttgatcgt ataccgtctt ctcttaacca gcagtatcct tagttttaat
     1381 gactactcga taggttcctt tagaaccgtt atagtcatct agttttaaaa aagcattcca
     1441 aacattcaaa aatagttgga acttccctta ataaatccgt cactttcttt ttcaagatag
     1501 cccaagcttg ctcaatagga ttcaaatccg gtgaataagg tggtagaggt aagaaaaagt
     1561 gtttatcttg gatgcagagt tcatccaaaa tgttcttggg atgaaaacta gcattgccca
     1621 tgacaataac atgaggtgtc ttcaaagcag gtaggagttg cgttttgaac cactccacaa
     1681 agaaatcgct tgtcatgctt ttcttgtaaa tcatgggagc tataaactct ccgtctactt
     1741 gtcctgcaac aattgaagtt cgctcaaaac gacgtccgct aatcttttca tagactttct
     1801 cccctctagg agcccctgca taaggacgat agaggtagcg gtcgattcct gtttcatcaa
     1861 tatatacgat tggtaaatct tttaggttat ccaaaatatc aagaaactca gcgactttct
     1921 ctgactcttg ttccttaaag atcgtcatct ttttttaaag tgaccttaat ctgctttaaa
     1981 gctgcccata ctgaaggaac agcacaatca aaatgtgccg caatttcccg taaaaaagca
     2041 tctggatgag cctctacaaa ggctttcaat tcttctaaag ggatcttacg ctttttgacg
     2101 actcgctttt tccgctctaa gttcctttgt tcacgtcttt cttttcccac gtgaagagag
     2161 ttctgacgcc aacaccaaaa aactttggcc gcctcgacat gtctgtgccc tcctttgatg
     2221 gaatctaatg ctccttgttt aaaatcagta ttatatgcca tagctttatt agaccatgct
     2281 tattttaaac taagcaacta tatcaatgtt ttgttatgag aagacttact ttttttactg
     2341 aaattgaatt tttcctagcc tcaacatcat ataaccccaa aattcaatct gacctggttt
     2401 gaagagatgt tcgaagcaga taaggtttta ctaaaactaa aaaaaatgat ataatcaaac
     2461 tgattaaatg ttttaaaaat aaaggagaat ttgaatgtct taccaagaaa attaccagaa
     2521 atgggttgat tttgtggagc ttcctgacta ccttcgtcaa gatttggaaa atatggacga
     2581 aaaaactaag gaagatgcct tctatacaaa tcttgaattt ggtactgcag gtatgcgtgg
     2641 cttggttggt gctggtacaa accgtatcaa catctacgtt gttcgccaag ctactgaagg
     2701 attggctcgt ttgattgagt caaaaggtgg aaacgagaaa gaacgcggtg tagcaattgc
     2761 ctacgatagc cgtcacttct cacctgagtt tgcctttgaa tctgcggcag ttcttgctaa
     2821 acacggcatc aaatcttacg tatttgaaag ccttcgtccg actccagaac tatcatttgc
     2881 agttcgtcat ctcaactgtt tcgcaggtat catggtcaca gccagccaca accctgctcc
     2941 atttaacggt tacaaggttt acggtgaaga cggtggacaa atgcctccac acgatgcgga
     3001 cgctttgact acttatatcc gtgcaatcga aaacccattt gcagttgaag ttgctgatgt
     3061 ggaaactgaa aaagcttctg gcttgattga agttatcggc gaagctgttg acgtagaata
     3121 ccttaaagag gttaaggacg taaacatcaa cccagccttg attgaagaat ttggtaaaga
     3181 catgaagatt gtctacacac cacttcatgg tactggtgaa atgttggctc gtcgtgctct
     3241 tgcccaagca ggatttgact ctgttcaagt tgttgaagcg caagcaactg ctgacccaga
     3301 cttctcaact gtaacatctc caaacccaga aagccaagca gcctttgccc ttgctgaaga
     3361 acttggtcgt caagttggtg cagatgttct tgtcgcaact gacccagacg ctgaccgtgt
     3421 tggtgttgaa gttcttcaaa aagatggtag ctacctcaac ctttcaggta accaaatcgg
     3481 tgctatcatg gctaaataca tcttggaagc tcacaaaaac gctggaactc ttcctgaaaa
     3541 tgccgctctc tgcaaatcta tcgtttcaac tgacttggta acgaagattg ctgaaagcta
     3601 cggcgcaact atgttcaacg tcttgacagg tttcaaattt atcgctgaaa aaatccaaga
     3661 attcgaagaa aaacacaacc acacttacat gatgggattt gaagaaagct tcggttactt
     3721 gattaaacca tttgtacgtg ataaagatgc catccaagcc gttcttgtcg ttgctgaact
     3781 tgctgcctac taccgttctc gtggtttgac acttgctgac ggtatcgaag aaatctataa
     3841 agaatatggc tactacgcag aaaaaacaat ctctgttact ctttcaggtg tcgatggtgc
     3901 tgaacaaatc aaagcgatta tggctaaatt ccgcaacaat gctccaaaag aatggaacgc
     3961 aacagctatc actgtcgtag aagacttcaa ggcacaaact gctactgttg ctgacggtac
     4021 tgttacaaac ttgacaactc ctccaagtga tgtgttgaaa tacacacttg ctgacggttc
     4081 atggattgcc gttcgccctt caggtacaga accaaaaatc aagttctaca ttgcagttgt
     4141 aggagaaacc aacgaagaat cacaagctaa gattgctaac atcgaagcag aaatcaatgc
     4201 atttgtaaaa taaagaccta taaaagatga gaccaaccaa cctcatcttt tttcgtatca
     4261 aatctaagca attttagaaa ctttatggca tactagactt atcaatgaaa gcgaggtaat
     4321 ctcatggaac aatttttaga taacatcaaa gaccttgaag tcactacagt tgtgcgtgcg
     4381 caagaagctc ttgataaaaa agaaactgca accttcttta tcggtcgcaa aacttgccct
     4441 tactgccgta aatttgcagg tacattgtca ggtgtcgtag ctgaaaccaa agctcacatt
     4501 tacttcatca atagtgaaga accaagccaa ctcaatgatt tgcaagcatt ccgctcacgc
     4561 tatggaatcc caactgtacc aggttttgtt catattacag atggacaaat caacgtccgt
     4621 tgcgactctt caatgtcagc acaagaaatc aaagatttcg caggattgta aaaaatcagc
     4681 taacaagtct taaaatcaca aaaacgcata atgtaaggtg caaaaacctt gatattatgc
     4741 gttttattgt tcctaaaaca gttacatcag catttcatta cagaacattt taattttgga
     4801 agtcaaatca atttttaaca atgttttaga aatcacagtg ggctattcca tattaaatta
     4861 tccagattca atcgctatta tcgttttcct agattacaaa aaaactgcgt tttgctaatc
     4921 aaaacgtagt ctcagccact attttatctt actgtccttc ttttacttct ttggttgcta
     4981 catcttctcc aaaccatttt tggctgattt cttggaactt gccgtccttg taaagactag
     5041 aaaaagcttc atttatcttc ttaaccaagg ttgtatcttc cttacgggct ccaaccgcaa
     5101 aagcttctgt ttctagtcca actgtaaaga cattataatc gtttaaaaca ccttctgctt
     5161 ctaaataata gtttgcatag acacggtcaa tcaatagacc atcaattcga tcgtttttca
     5221 aatcaatcaa ggcttcatta aaggtttggt attgattcgc ttccttatta gcgacaatat
     5281 tcttcaaaat ttctggattt gcttcaaagt ccgcataacc agatgaacca gcttgagctc
     5341 ctaatgtctt tccagtcata tcctttgcag tcgtgatacc agatgatttc ttcgtaacca
     5401 atacctgctc attcttcata tatgagttac tgaaagccac cttttcacgg cgttcgtctg
     5461 tagcggaata gccattccaa atcagatcaa tcgttccttt tgtcaattca gcttctttca
     5521 aatcccaatc aatcggttgc caatttaccg tgattccgta tttttcaaaa acagctgtag
     5581 ctaaatcaat atcaaatcct gcataagaac catctttctg agcaaatccc attggaacaa
     5641 aagtactatc aaatccaata gtaatagact tgttagactg gtactttgac caattatctc
     5701 cactagtttc gctagaattt ttcccacaag ctactaagaa caaagcagtc atcagactga
     5761 ctaatacaag catccatttt ttcatccatt tttcctccta tttaggttct actttcaata
     5821 atacatctgc gatattttca gcaaactgca aatcatgggt aaccacaatc tgggtcatcc
     5881 caagttccct attttgcaag attagcttct ccacttccaa acgtaattct ggatccaggg
     5941 cagaagttgg ttcatcgtag ccaatgattt ctgggtcaat catcatagca cgcgccaaag
     6001 ccacccgctg cttttgccca ccagatagtg agaaaggata ggcctctgcg tgtcctccta
     6061 gtcctaactg ttccaagagt ccactcgcct tcttctcagc ctcttcctgc ttcattccca
     6121 tggtcttcac aggcgataag gtcaaattgt ccagaactga taaatgaggg aacagttgaa
     6181 aatcttggaa tacaaatccc agtagattgc gcttctgcaa ttcatccagc tctaaaggtt
     6241 gtccattata aaagatttgc cctgaatcaa tggtttcaag acctgcaagc atacgtaaaa
     6301 gagttgtctt acctccacca gaaggtccaa cgatagccag gatttgcttt tcaggaatac
     6361 ttagactgaa attagacagg atttgtttgt ctccaaagac tttattgata tttcgtaatt
     6421 ctaacatggc agcctcctat ctataataac tatacttctt ctcaactttt ttggaaataa
     6481 ttgtcacaat cccaatcaaa atcaaataaa tggctcctgc caagaacata ggaactagac
     6541 tagcatcgcg gttagcagct gttcgactag ccaagataag gtctgaaatt ccgagagcat
     6601 agaccaaaga agtatccttg accaaactca taacttcatt aaagacacta ggaagaacga
     6661 tcttggtcac ttggggcaag ataatatagc gcactctgtc aaaagggcta aacttcaaga
     6721 ccttggcggc ctcatactgt cctcttggaa tagtgtcaat tcccccacgg aaaatttctg
     6781 caaagtaagc tgcatagttg agaacaaagg caataatagc tgcaggaagg cggtctaaac
     6841 gaatcccaat acttgggagc acataataga taaaaatcag ttgcaagagt aagggggttc
     6901 ctcgcataac ccagatgtaa atgttaatca gataatggag gggcttccaa tggacttgca
     6961 aggcaaaggc aatcaaaacg cccaagggaa tcgaaaatag caagaccagt gcaaagacct
     7021 gtacagtcgt gctcgcacca ttcagtaaac tcggtaatat ctcaaataaa taagacatac
     7081 tgcacctcct aaaagtaatt gttcctatta tagcatgaat aaacaagatt accaagtatt
     7141 tttgtaaaaa gattctacca tatacaaata aaaaccgtag ctatcaaaag agataaacta
     7201 cagttctata tgtttaaaca ttcttacaat ctctcaaaca gttcttgcat ttgcacatca
     7261 tctggaacca gttttaagta agtgtgagca tggacttttg cttcttcaaa atgtcccaat
     7321 tcacgcaaga gatagatata gtgttccaga aattctggat tgtccttcaa atctcctatc
     7381 aactcttgat aatgctcata agcagtatcc aaatcgtcca tttcttgata agaacgagca
     7441 atcatccact tggtcaaaag attttctgac tcctcactct gcaagtctag aatatcctca
     7501 taacgctcct gctccagata aatagtggct aaacgaagca agatttcttc tgtatcctca
     7561 gcgtcttctt ttgcagtaag gagataattt tctgcaccac tagcatcatg caattcataa
     7621 gaaaattgtg aagcagctag caagaggcga gtttcaaagg gatttttctc taatccttgc
     7681 ttagcgatac gcagggcttc ttgaacttga tgttccttat gtaaagcctg actgtaccca
     7741 tactcatagc cttcaaagtc aggagaaatg gtatcaagct gcttaaagta gagggtggct
     7801 ttttgatatt cttcttgatc aaaataaaga ctggccaact caaaagctgt taagtcatcg
     7861 tattctaact ccagggcttt ttctaaaaac tcagtagccg tttcaaattt ccctaactga
     7921 gcataggcaa agccaattcg ttgataggtg gaaatgcccg tttgctcata aatcgagcga
     7981 ttatctaact gggcataggc ttgaatagcc gcttggtaat tttccaactc actatccaac
     8041 tctgccaaac ccaatatcaa gagagaatcc tctgagtagg tcaaggcctc caataatttc
     8101 tcacgtgcca catctgtcaa accttccagc tggtaaaggt ctgccttcag agccaaagac
     8161 gagacatacc agtcactgtc agcttggatt tcctcaagat aggtaaaggc ttcttctatt
     8221 tgaccatcct cgctagcaat tgcagctaga ttaagatgaa cctctggaaa atcctctaca
     8281 attttcaggt aaatttcctt ggcctgagga tagaaaccaa tcccttcaag ataagttgcc
     8341 aactcataca gaagatcact tgaatcattt tctaaagctt tggcgaaata atgctcagcc
     8401 ttagttaaat cttgctcctc caaagcctgt aacatctgtt gactattgtt cactcttgac
     8461 ttcctcaccc tctaattcat atagaccact gactacctta taccattcga aaatggctga
     8521 aatgacaacc ttagcagagg cataaaccgg aataccaagt aaaactcccc agataccaaa
     8581 catagatcct gaagttaaca aaacaaagag aacattaata gggtggatgt ttaattgact
     8641 tcccaaaatc aatggagaga caaaacggcc ttcaatagtt tgttctacga taaagacaat
     8701 cactactttc aaaagcatga ctggaccagc aatcaaaccc aatactagag caggaagcat
     8761 ggctagaaag ctaccaagat aagggaccag atttaaaata ccagcagtaa cccccagcgt
     8821 aaccgcatag cgtagaccaa taatcttgaa gaagatgata aacattactg ctacaataat
     8881 agccactgtc acttgccctc gaacatagtt ggacaactgt tgattcacat ctgataaaac
     8941 ttgtccaaca ggttccttca attttcttgg aatgaattgg gtcaaatagt tacgcaagcc
     9001 tttcccatca cgcaagagat aaaagagcat gaaaggaacg ataatcaagg caacaatcac
     9061 ttgagaagct ccgctaataa aggcactcac ccagttgact gcctgagatg aaaccttact
     9121 tgccaaaact gtagcctggc tagaaaaatt ggtcaaaact tgctctaatt gaggtctgaa
     9181 atcatctggc aggtgctggg ctaccaatcc attaacaatc ctatctatat cttctaagta
     9241 aacaggaacg tttcttgcaa aggtcaaaac ctgacgttgc agatttggaa tggcgactgc
     9301 caagccccaa atgataaaga gagcgatgat aacaaagaca atagtgatag ctataacacg
     9361 attaacctta tgcttctcca tccaatcaac aataggattc aacaaataat ataacaaacc
     9421 agacaaaatg actggcaaca tcacaactgc taaaaagtct aaaacaggtg aaaatagaaa
     9481 actaatctta cttaaaataa aaagattcag tcccaataat aaggttacta aaaataccgt
     9541 aattgccttg ttatctaaaa accacttgaa aaaccaagat aggctaaaat gtttctcttt
     9601 ttgctccata aatacttcct ttctattgtt ctctcattat accatttttg aaacaaaata
     9661 actctttttt aaagtgctta catctaattg gatatcttta atttacttgt ttttgtgata
     9721 taatagtctt atctttacac agaggtatag taatgaaaga aactgtttat tttggaactt
     9781 atacacgtcg tacttctcaa gggatttaca aggcagactt tgatacagaa actggtcagc
     9841 tttcaaatct agaacttttt gcagctgagc caagtccaac ctaccttgcc tttgaccagc
     9901 accaacattt atacactgtt ggtagccaag acgataaggg gggaattgca gcctatcaaa
     9961 ctgacgggac tgtgttaaat catgttgttg aagaaggagc tccccactgt tatgttgctg
    10021 tcgatgaaaa gcgtgatttg gtttacgcag ccaactatca caagggacaa gtccttgttt
    10081 ataaacgcca ggaagatggt agtcttctac ttagtgatat ggatcaacac agtggccaag
    10141 gtccacatga aaatcaagct tccccccatg ttcactatac agatttaaca cctgaccact
    10201 atctagtgac ctgcgacttg ggaactgacc aagtcatcac ctatgacctc gatcaagaag
    10261 gaaaattatc taagctctat acctatcaca gcaagccagg agcaggctca cgccatatca
    10321 ttttccataa ccactataaa atcgcttatc tcatttgtga actcaatagt actatcgaag
    10381 ttttaatcta cgatggcgtt ggcgaatttg aacgtatgca ggtcatttca actttaccgg
    10441 aagcttacga aggctttaat ggaaccgctg ctattcatct ctctaaagac ggtaaatacc
    10501 tctacgcttc taaccgtggc catgattcta tcgcagtata taccatcctt gcggacggta
    10561 gcttagagtt attagaaatc gttccaacgc atggtcagac tccacgtgat tttgatttga
    10621 cacccgacca aaaatttctc attgttgtcc atcaagactc tgacaatgca actgtcttta
    10681 aacgtaattg tgacaatggt cgtctagcag aactctccaa cgacttccat gttcccgaag
    10741 cagtctgcat ccgttttgct ccttaaaaca ccataaaaaa tgaacttggt attttcaagt
    10801 tcattttttc ttatagtcta tttccgacat taatacggtt aatagcacgt tgcaaagcaa
    10861 tcttagcacg acgttcttgg tcaatcaaat gtttgtcttg tgcttcttca attgcacgtt
    10921 ctgcacgaag tttggcacgt tctgcacgac tgatatcgat atcacgagca cgttctgcag
    10981 agtcagcgac gattgtgatc atatcattgg caatttcaat aacaccaccg tttactgcaa
    11041 tccagttcac ttgatcttta tcatcgatac gttttacctt tacttcatca actgctaaaa
    11101 ccgcaatcat attttcatgt cgtggcaaga tccccatctc accatccaga gttcgaaccg
    11161 atacatagct ggcatggtga tcatagacga gaccatctgg tgtcacgatc tggacagtta
    11221 actgagccat agttcacctc ttaaaatccc attttttcag cttttgcaat cacatcttcg
    11281 atagaaccta caccacggaa ggcatcttct ggcaagtggt cgtatttacc atcaaggatt
    11341 tccttaaagc cacgtacagt ttcagcaact ggaacataag aacctggctg accagtaaat
    11401 tgttccgcaa cattgaagtt ttgtgacaag aagaactgga tacgacgggc gcgagcaacc
    11461 aaggtctttt cttcatcaga aagttcatcc ataccaagga tagcaatgat atcttgcaat
    11521 tcatggtaac gttgaaggac acgttttact tcagcagcaa ctgcatagtg ctcttctcca
    11581 acgatttcag gtgccaaggc acgtgagctt gaagcaagtg ggtcaacggc tgggtagata
    11641 cccaattgta ccaacttacg ttccaagttt gttgttgaat ccaagtgagc gaaggctgtt
    11701 gctggcgctg ggtcagtata gtcatccgct ggcacataga tagcctggat agaggttaca
    11761 gaacccttct tggttgatgt gatacgttct tgcaattgac ccatttccgt agcaagtgtt
    11821 ggttggtaac caacggctga tggcatacga cccaaaaggg cagatacttc tgaaccagcc
    11881 tgagtgaaac ggaagatatt atcgataaag agaagcacgt cttggccttc cacatcacgg
    11941 aagtattcag cgattgtcaa accagtaagg gcaacacgca tacgtgctcc tggtggctca
    12001 ttcatctgac caaagaccat ggctgttttc tcgataacgc ctgattcttt catttcccag
    12061 taaaggtcat tcccctcacg agtacgttcc ccaacaccag caaatactga aataccaccg
    12121 tgctcttggg caatgttgtg aatcaattct tggattaaga cagttttacc aactccggca
    12181 ccaccgaaaa gtccaacttt accaccttta aggtaagggg caagaaggtc aataaccttg
    12241 atccctgttt caaggatttc agaagaggta gacaactcat caaaagttgg agctttttta
    12301 tgaattggct gacgctctgc gtcttctgta aaaggagctt ccaagtcaat ggtatctccc
    12361 aaaacgttga agacacgtcc caaagtttct ttacctactg gtacagagat tggacgacct
    12421 gtgtccaata cttccattcc acgagtcaac ccatctgttg attccatggc gatagtacga
    12481 accataccat ctcctaactc caaggctact tcaaggacga tttttgtttt tctttcgtca
    12541 tttttgtaga cgacaagtgc attgttaatc tcaggaagtt tttcccctgc tgcaaacaaa
    12601 acgtctacaa cgggaccgat aacctgagca attttacctg aactcatctc cttctcctat
    12661 tctatataag atactgtcgg ttcctagctc aactaggtcc taagttcatt ttcatacgag
    12721 ctggactaga gcctattcta aggcactagc acctgctacg atttctgtaa tttcttgtgt
    12781 aatcgccgcc tgtctggcac ggttatactg aattgtcaaa tcattgatga ctttcttagc
    12841 attatctgtc gctgtttgca tggctgtcat acccgcagca ttctcagctg tcttggcatc
    12901 tataatggca ccgtaaatca tactttctgc aaactgaggc aacaactgct ccagaatttc
    12961 ttctcggctg gtttccaatt caaaagtcaa gctgtactct tcatccgctt catttggatc
    13021 caagtcaaca atcggaagca tttgttccac acgcatttga ctggttagcg tattgacatg
    13081 gtggttgtag caaacataaa gctcatcaaa gagttcattt tggtacattt caacagtttt
    13141 tgaaataatc ttacgaactt gatcaaagct aggttggtct gccaagccac gtaattcata
    13201 aagtggttga ataccgcgag ccttaaagaa atcagctccc atcccaccga tacagatcat
    13261 ttcaaaacct ttaccgtctg ggtggtattc ttctttcaac tccataacag ctttcaaaat
    13321 agaggaatta taacctccaa ccaaaccgcg gtctgaagtg ataacgatat agcctgtctt
    13381 cttcacagaa cggctaatca acatcggatt agttgaagca ccagctccat taccatgaag
    13441 gatatctgtc aaaagtttac gcactttctg agcgtaaact tggaagttgc gagcagcttc
    13501 ttcagagcga cctagcttag cagccgatac catttgcatg gcattagtga tttgactcgt
    13561 attttttgtt gaggcgattt ttgttttaat atcatttaga gatactgcca tctgacacct
    13621 ctattcttat tggaagctag attgattgag aaactctgta atcgcagcat ccaagactgc
    13681 ttcttctggc aagtcttttg tatcacgaat ggtttccaaa atctctggat gttgagcatc
    13741 aaagaaggca tggaactctt cctcgaaacg aacaatatca tctactggaa cagtatccaa
    13801 gaaaccatgt atcaaagcat aaagaatggt tacttgtttc tcaacaggta atggtttgtg
    13861 aacaggttgt ttcaagacct caacggtacg acgtccacgg ttcaacttag cctgtgttgc
    13921 tgcgtccaag tcagaaccaa acttagtaaa ggcttccaac tcacggtatg aagcaaggtc
    13981 gatacgaagt gtaccagcaa ccttcttcat ggctttgatt tgtgcagaac cacctacacg
    14041 agatacagat gaacccgcat cgatggctgg acgaatacct gcattgaaga ggccatcgcc
    14101 aaggaagatt tgtccatcag tgatagaaat cacgttggtt gcgatatagg ctgagatatc
    14161 tcctgcttgt gtctcgataa atggtagggc tgtaattgat ccaccaccaa gttcatcaga
    14221 aactttagct gagcgctcaa gcaaacggct gtggagatag aaaacatccc ctgggaaggc
    14281 ttcacgacct ggaggacgac gaagcaagag cgacagttca cgataagcta ccgcttgttt
    14341 tgatagatca tcgtatacaa tcaaaacatg cttaccttga tacataaatt cttccgccat
    14401 agcgacccca gtataaggag ctaggaagag caatggagat ggttgtgaag cagaggctgt
    14461 cacaacgatt gtgtagtcca aggcaccgta ctgacgaagt gtttctactt gcgtacgaac
    14521 tgttgattct ttttgtccaa tcgcgacgta gatacagatc atatcttgat ctttttggtt
    14581 caagattgta tcaatcgcaa tggttgtttt ccctgtctga cggtcaccga taatcaactc
    14641 acgttgacca cgaccaatcg gtacaagggc gtcaatagct ttcaaaccag tttgcaatgg
    14701 ttctgaaaca gacttacgtt gcataacacc aggagctggt gcttctactg gacgagtttt
    14761 atcagtgtgg atttctccaa gaccgtcaac tggacgacca agcggatcca caacacgacc
    14821 aatcagactt tcacctacag ggacttccat gattttccct gtacggcgga ttgtatcgcc
    14881 ttcacggata tctgtaaagt cacctaggat gataatacca acgtctgttg actccaagtt
    14941 ttgagccata ccataagagc cgttttcaaa attcaacaac tctccactca tgacattttc
    15001 aaggccgtga gcacgcgcga taccgtcccc gatataggtt acaacacctg tttcagtcac
    15061 atcaaaattg ggtttgaaat tttcaatttg ttgcttaatt aaagcgctga tttcttgtgc
    15121 gttaattgcc aaaagaacac cactttctat ttcaaatttt ctttaacaac tttaagttgt
    15181 tgtttaatac tcacatcaat tgtcttgtga ttggcaaaaa tgacaaaacc accaatgaga
    15241 ctttcatcga tttgttcttt tacactcctt actttcagag acattttttt ctcaatcaaa
    15301 gggagcaaac gagtcttctg ttcatcagtt agaggatgag cagacgtaat cgtcacttca
    15361 aatcgatttg tttctttttc aagtcggttc aagcaatcta caagcacatc ataaaaaaga
    15421 tttgctctgt gattgtaggc cagaacctgg ataaagtttt gtaataaagg cgacacagaa
    15481 tcttggaaaa aagcaattgt tttttcctta tccgactcgt ctactgccac ttgttttaaa
    15541 aaagaaggca gacctgtttt ttcaacaact tgcttgattt gagtcaagtc tgaaaagata
    15601 cggtcttctt ctcctttttc aagtaccaat tggacaaaag gcatgctgta tttttcaatt
    15661 acctttactg ttttcttgtc cattaagctt ctcctagctg atcgatatac tgatcaatga
    15721 gtgctttatg ggcatgactg tcaaggtttt gtgagatgat tttaccagct aagctgatgg
    15781 tcagatctgc gacctcaccc ttaacactct gtaaagcttc tactttattt tgagcaattt
    15841 cttgattggc tttttctttt aagtgtcctg cttctagttt agcatctgct aagatattag
    15901 ccttactttg ctcagctgtt tcctttgcat tttcaatgat tgtcttagct tctttacggc
    15961 taccagccaa ttcatcttcg cgtttttgag ccaatacttc tgctttttga cgggcttctt
    16021 cagctctgtc aatatctgaa gcaatttttt cagctctttc ttcgaaaatg cctgtaatat
    16081 tagaccatgc aaatttttta atcaagacta gcaaaagaat aaaagagcca gtgattaaaa
    16141 taaaattacc aattaattca cctactgtta cgtgcatcag ttactccttt ctattcctct
    16201 tcaatattaa tcttattccc taaatacaca gatgtcaaaa gagtaaaaac ataagcttgg
    16261 atgcaggaaa taaagacaga aaatgcagtc caagccaaat tagctccaaa ggctactgga
    16321 taccaataaa tagcttggtg ggaaagaaga agtaacaaac tcgtcatgac ctctcctgca
    16381 aagatattcc caaaaatccg caaagccaaa gataagaagt ttgtaaattc ttccaagata
    16441 ttcatcggta tgacaaaaac aggactcata aaagatttta tacttttttt aaatccacga
    16501 cgacgaacgc tttctatatg tgtcaacaaa atgacaagaa aagataaggt taagtcatac
    16561 tgtaaattag cggttggcga actccaccag ttagtcccat cgatcgtttg aagctttgtc
    16621 attaagccaa ggttattggc aatcaccatg aaaaggaata aacaaaggaa aaagagtgaa
    16681 taatctttca tgtagcgcga accaatgtta ggttctgtaa atccaataac aaagtcatag
    16741 acatactcaa gtacattttg ctttcctttg ggtttcaagg tcatattgcg gcttgcccaa
    16801 taaataaaga caaaaataac tcccacaatc aacaaagtca tggctaacat agtcagattg
    16861 aagataacag gaccaataga gatgattgga ttaatacttt cttccatcta aaatcctccc
    16921 ttttcttctc gttccatgta tttatttgat aataaatgag aagacaagag ttacaaagaa
    16981 agttccttca ataaaggcaa cacctaaaaa catcaaacta cgaaactcag aaagcatatc
    17041 tggttggcgt gctactgatt taaacagtcc attcatcaat aaaccttcac cgacagatac
    17101 gcccatacag gcaatacata agcctaaaaa tgttaaattc ataacaaatt ctcctttaaa
    17161 ataaaattta cttacttagt gtagtcctaa aatttaaatt tgtcaacttt taaccgctat
    17221 tggaagcgtt taataaaaat tatttccatt ttgctaaatt tcaagttcaa gttagccatc
    17281 ca
//
LOCUS       DAVBDR010000044        16715 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.044, whole genome shotgun sequence.
ACCESSION   DAVBDR010000044 DAVBDR010000000
VERSION     DAVBDR010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16715)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16715)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16715
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.044"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            complement(<1..484)
                     /locus_tag="VQ540_001522"
     CDS             complement(<1..484)
                     /locus_tag="VQ540_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET2545306.1"
                     /translation="MTIEPGQRIALVGQSGSGKSTLSKILSGLYKIDTGKILFDGVNI
                     NQIDKKILSQNLGVVPQDSFLLNRSILDNITLKNEVTSQKIEEVCKAVQIYDEIMAMP
                     MKFNTIISEMGSNISGGQRQRIALARALINNPSIVILDEATSALDTINEERITKYIQS
                     Q"
     gene            complement(653..1966)
                     /locus_tag="VQ540_001523"
     CDS             complement(653..1966)
                     /locus_tag="VQ540_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000197307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2545307.1"
                     /translation="MTRKVPNIEQMSQIECGLCCCLSILHFYKSKETLLDLRRDIEKG
                     RDGYSIGDLKQLLNKRNFDTGSYQVKDVNKISELPLPLIAFWDNQHYVVIYKVKKNKV
                     YIMDPSKGYINYEFKEFSKHFSNIVLLSFPNENYQSLKSQFPSPWIRVFSSFSKVKGR
                     LILTLLFSIISYLIILSVPVMTSKFINSALGNTFSFQTSFLILFSLLCLYLISILARS
                     MGILFSNIFFSRDIESFTFKHLLKLPYSFFELRAKGDILYRISSLSGFRELFTNQVVG
                     GVVDIGTILSVVIYMFLSSKTLSIIALILSLINFLFLFSTRKIMYDTVNRELQEQSLI
                     YSVETEALNTISSIKISGLEDEIYENWSKYLKNVLTKYKKRSIVHILYNSATNVFQLF
                     APIIILIFGLDNVLNGKILLGEVVAFQTMASILFSSEISIFNAYT"
     gene            complement(1959..2507)
                     /locus_tag="VQ540_001524"
                     /pseudo
     CDS             complement(1959..2507)
                     /locus_tag="VQ540_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000059560.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(2588..2650)
                     /locus_tag="VQ540_001525"
     CDS             complement(2588..2650)
                     /locus_tag="VQ540_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_128650800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SHP2/SHP3 family peptide pheromone"
                     /protein_id="HET2545308.1"
                     /translation="MKKISKFLPILVLVMDIIII"
     gene            complement(2819..3807)
                     /locus_tag="VQ540_001526"
                     /pseudo
     CDS             complement(2819..3807)
                     /locus_tag="VQ540_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050775.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
     gene            complement(3756..4883)
                     /locus_tag="VQ540_001527"
                     /pseudo
     CDS             complement(3756..4883)
                     /locus_tag="VQ540_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000423473.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alpha amylase N-terminal ig-like
                     domain-containing protein"
     gene            complement(5046..5930)
                     /locus_tag="VQ540_001528"
     CDS             complement(5046..5930)
                     /locus_tag="VQ540_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HET2545309.1"
                     /translation="MKKAMVIINPTSGGEKALDYKEKLENKAKEYFEYVETKITEKAL
                     DATHFAEEASREQYDAVVVFGGDGTVNEVISGIDERDYIPKLGIIPGGTGNLITKLLE
                     INQDIDGAIDELDFDLTNKIDIGKANDNYFGYIFSIGSLPEAIHNVEIEDKTKFGILT
                     YAVNTMKSVMTDQVFNIKVETENGNYVGEASHVLVLLTNYFADKKIFEENKDGYANIL
                     ILKDASIFSKLSVIPDLLKGDVVANDNIEYIKARNIKISSDSELESDVDGDKSDNLPV
                     EIKVLAQRVEVFSKPKED"
     gene            complement(6042..6896)
                     /locus_tag="VQ540_001529"
     CDS             complement(6042..6896)
                     /locus_tag="VQ540_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HET2545310.1"
                     /translation="MLGAIIGDIVGSVYEWNNIKTKDFPLFRKDCFFTDDTVMTCAVA
                     EAIMNGGQKDDFIDAMKKYGRMYPNADYGARFNAWLNSDNREPYNSFGNGSAMRISPC
                     AWIMDCGFYAKTGIWPSSRGLTSLSAEVTHNHPEGVKGAMATADAIFLCRFYFGGYCR
                     EYEQSINDNLTECKRRIKDYIEKEYDYNLSQTLDEIRPNYRFNETCQETVPQAIIAFL
                     ESRDFEDAIRNAISLGGDSDTLAAITCNIAEAAYGIPDWIKDKAYSYLDEPLKDVVRR
                     WENRIKAY"
     gene            complement(6954..7712)
                     /locus_tag="VQ540_001530"
     CDS             complement(6954..7712)
                     /locus_tag="VQ540_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HET2545311.1"
                     /translation="MVVYIRQSKLPSEVSINKYNAQVGAYLQGEEVILYQSFSEIKEL
                     TSEDIVVDYIMETRALLKMMGLNVPVYDYPIELKEFYGRKIYAGILGEIVNIPDNWGK
                     FIKPKAGSKVFTGRVVNGTHDLIGIGLPFDYPIWISEVVEFIAEWRCFVLDGRVLDVR
                     PYTGDYHAQFDASVIDEAISCWKDAPIAYGLDIGVTRDGRTLVVEVNDGYALGNYALS
                     PLKSINFHRARWKEMVKPYFEKNEIFKIQQDVVF"
     gene            complement(7774..7962)
                     /locus_tag="VQ540_001531"
     CDS             complement(7774..7962)
                     /locus_tag="VQ540_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family transcriptional regulator"
                     /protein_id="HET2545312.1"
                     /translation="MATDKNRIMISLDDKNLEKLENLVEDARDRRGMRLTKSQVIELL
                     LNTVDYFDDIMGAIYSKK"
     gene            complement(8284..8850)
                     /locus_tag="VQ540_001532"
     CDS             complement(8284..8850)
                     /locus_tag="VQ540_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2545313.1"
                     /translation="MVILELYQNDYSKDLVAFDSIEDGKAFVAQIPGYTLETEDGFEV
                     EYFNPKNIPDYMEIIFNGNIVPLSKFMFDPEENVNIIWKEISNLSLKNDRVIEGYSKI
                     DAYVVNNHEVKTYVETRETNYRKAKDFLESRGYEIDRSFFGSEDGEAILYRKKGIEVW
                     HFLCHLDPMFVEIEDVEGYVKEEVGEIQ"
     gene            complement(9118..10797)
                     /locus_tag="VQ540_001533"
     CDS             complement(9118..10797)
                     /locus_tag="VQ540_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HET2545314.1"
                     /translation="MSKEKIKVYLYTRVSTSIQIEGYSLEAQKSRMKAFAIYNDYEIV
                     GEYEDAGKSGKSIEGRIQFNRMMEDIKSGKDGVSFVLVFKLSRFARNAADVLSTLQIM
                     QDYGVNLICVEDGIDSSKDAGKLMISVLSAVAEIERENIRIQTMEGRIQKAREGKWNG
                     GFAPYGYKLEDGKLFINEEEAVAIRTIFDQYVNTTIGANGISKYLENHGIRKIPRQNG
                     KNPLFDAGLIRKILKNPVYNGKIAFGRRTLEKVHGTRNEYKQVEQDEYLISEGIHEAI
                     VSDEVWQAAQVKLKSQAKKYEHVNKGKDTRTHLLSGIVKCPICGVGMFGNKCIKKKKD
                     GTKYKDFYYYGCNHRQMIRGHKCTFSKQIREELLDDAVAEVIVKIVSNPKFASMMQEK
                     INMKVDTSEIEKEIDNYQKELRKSHSTKFKLIEEIDNLDVEDKHYKRRKQDLDDRLYR
                     MYDKVDELESSLIDAKAKKQTIEAEKLTGDNIYKVLIYFDKLYKVMNDVERRQLISAL
                     ISEIQVYEEKQSNGQWLKSITFKLPIIEENLNIGLDNDEQVECVSLLEKRS"
     gene            complement(10889..11050)
                     /locus_tag="VQ540_001534"
     CDS             complement(10889..11050)
                     /locus_tag="VQ540_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005761276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2545315.1"
                     /translation="MDNDWNGLADLIANLIAKYAGALDLDNLPDPTPAKNQEMKNSFD
                     MAKTQIETD"
     gene            complement(11734..12048)
                     /locus_tag="VQ540_001535"
     CDS             complement(11734..12048)
                     /locus_tag="VQ540_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001835032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2545316.1"
                     /translation="MGITWKDIEIDKEREGEIDKKSTPIFYGEFKNVRLSKEEYKNLK
                     EKLNSHTDIMINKLSRYMESSGKTYQNHYVTILKWYEEDKDKLRQKGLNKKMNYDVGE
                     SL"
     gene            complement(12014..12403)
                     /locus_tag="VQ540_001536"
     CDS             complement(12014..12403)
                     /locus_tag="VQ540_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HET2545317.1"
                     /translation="MPKRYLLDGKTPRISATNIDNGILGYYEDIDDKNYRVFENFISV
                     SFLGAVFYHKYKASLDMKIHCLKLKNKELNKEVAFYLTSIIRQALKNTEYKDQISSTV
                     LPDIKIKLPIDSRGTPDWNYMERYRDR"
     gene            complement(12791..13585)
                     /locus_tag="VQ540_001537"
     CDS             complement(12791..13585)
                     /locus_tag="VQ540_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000677523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2545318.1"
                     /translation="MKGLWSNNLTCGYDEKIILENINIKIPEEKISVIIGSNGCGKST
                     LIKTLSRLIKPLEGEVLLDNKSINSYKEKDLAKHIAILPQSPIIPESITVADLVSRGR
                     FPYRKPFKSLGKDDLEIINRSMVKANVEDLANNLVEELSGGQRQRVWIALALAQDTSI
                     LLLDEPTTYLDISYQIELLDLLTDLNQKYKTTICMILHDINLTARYADYLFAIKEGKL
                     VAEGKPEDILNDKLVKDIFNLEAKIIRDPISNSPLMIPIGKHHVSS"
     gene            complement(13585..14592)
                     /locus_tag="VQ540_001538"
     CDS             complement(13585..14592)
                     /locus_tag="VQ540_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HET2545319.1"
                     /translation="MQNLIIGIQKRKNRITLFSSLFLLIIISLSFFILLIGDESYSFS
                     TLIKVLNSETVPGASFSIMEIRLPKLLAGIIAGWSFGLAGFIFQTMLRNPLASPDIIG
                     VTSSSSIAAVFCILVLKTNSLTTGIISITCGLTSSLILFLLAKKDGFSAARLIILGIG
                     FQAVTRAGTSFLLLKVARYELQEVMRWLSGSLSFTKLDDIPLVLIVSIIATILVLFFN
                     KRLEIIELGEEIAIGLGANPELSRLVLIFCAVSLTAFSTSITGPIACISFLAGPIALN
                     IGKKRSPILAGLVGILLVLLSDIFSQNILPARYPVGVVTGLLGSPYLIYLLIKMNRRN
                     I"
     gene            complement(14592..15599)
                     /locus_tag="VQ540_001539"
     CDS             complement(14592..15599)
                     /locus_tag="VQ540_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001244688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HET2545320.1"
                     /translation="MRNKKQINLGIIFVICLGLLITIFLSLKLGTKEINIRDFLATFG
                     MGNTNDDFIKSIIYKRIPRTIFAILAGSSLAISGVLMQSVTRNPIADPGILGINTGAS
                     LSVVIGLSFLGISSSISHISFAIIGGLVSAIFVYAIAVSGKAGLTPIKLALSGTCVSM
                     ALSSFVSFLILPNNNVLDKFRFWQIGSLGAATLSSISTLLPFIILGHLIAIFISSDLN
                     ALAMGDEMAVGLGVNVNRIRSLAIIASVLLCSSITAIGGPIGFVGLIVPHFCGLFISK
                     DIRTMTISSSFIGAELLLICDIIGRMLGKPGEIEVGIITAIIGGPVLIYVTMKNRGVN
                     N"
     gene            complement(15589..16614)
                     /locus_tag="VQ540_001540"
     CDS             complement(15589..16614)
                     /locus_tag="VQ540_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000790748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-siderophore ABC transporter
                     substrate-binding protein"
                     /protein_id="HET2545321.1"
                     /translation="MKNKFFLIAILAMCIVFSACSSNSVKNEENTSKEHAPDKIVLDH
                     AFGQTILDKKPERVATIAWGNHDVALALGIVPVGFSKANYGVSADKGVLPWTEEKIKE
                     LNGKANLFDDLDGLNFEAISNSKPDVILAGYSGITKEDYDTLSKIAPVAAYKSKPWQT
                     LWRDMIKIDSKALGMEKEGDELIKNTEARISKELEKHPEIKGKIKGKKVLFTMINAAD
                     TSKFWIYTSKDPRANYLTDLGLVFPESLKEFESEDSFAKEISAEEANKINDADVIITY
                     GDDKTLEALQKDPLLGKINAIKNGAVAVIPDNTPLAASCTPTPLSINYTIEEYLNLLG
                     NACKNAK"
BASE COUNT         5230 a         3153 c         2261 g         6071 t
ORIGIN      
        1 cctgactttg tatatacttt gttattcttt cctcattaat agtgtctaat gcactagttg
       61 cttcatctaa aattacaata ctaggattat ttattaatgc acgtgccagt gctatccgtt
      121 gcctttgccc acctgaaata tttgacccca tctctgagat gatagtatta aatttcatcg
      181 gcatagccat gatttcatca tagatttgaa ctgctttaca aacttcctct atcttttgtg
      241 aagtaacttc gttctttaaa gttatattat caagaatact tcggttcaat aaaaatgaat
      301 cctgtggaac tactcctaaa ttttgactta atattttttt atctatttga ttaatattta
      361 caccatcaaa taaaattttt cctgtatcaa tcttatataa tcctgatagt atttttgata
      421 acgtactttt tcctgacccc gattgaccga ctagtgcaat tctctgtcct ggctcaatag
      481 tcaaatttaa attttctatt acaggagctg agtctttgga ataagagaaa gataggtcct
      541 taatatctat tctaccttct aaagaacact ttttaagacc attttcaaca ttctcttcat
      601 tttcaagcca gatatcattt actctattta agtatcctgc tgccaaaata tactacgtat
      661 aagcattaaa tattgagatt tctgaactaa ataaaattga tgccatcgtt tgaaatgcga
      721 caacctcacc caataaaatt tttccattta aaacattatc aagtccaaaa atcaatataa
      781 ttataggagc gaacaattga aatacattag tagctgaatt gtataaaata tgcacaatac
      841 ttcgtttttt atactttgtc aatacgtttt ttaaatactt agaccagttt tcatatattt
      901 catcttctaa tcccgatatt tttattgaag aaatagtatt taatgcttct gtttctactg
      961 agtaaatcaa tgattgttct tgtaattctc tattaaccgt atcatacatt atttttctag
     1021 tactaaacag aaacaaaaaa ttgattaaac tcaatataag agctataatt gataatgttt
     1081 ttgaactaag aaacatatat attacaacac ttagaatagt cccgatatct actactcccc
     1141 caacaacttg gttagtaaat agctccctaa aaccactaag actagaaatt ctgtataaaa
     1201 tatctccttt tgccctgagt tcaaaaaaac tatatggtag tttaagcaaa tgcttaaatg
     1261 taaaactttc aatatctcta ctaaaaaata tattagaaaa tagaattccc atactcctag
     1321 ccaagataga aataaggtac aaacaaagta gagaaaataa aattaaaaac gaggtttgaa
     1381 aagaaaatgt attccctaat gcagaattaa taaactttga agtcattact ggtacggaaa
     1441 gtattattaa gtaacttatt attgaaaata gtaacgtcaa aatcaatcga ccttttacct
     1501 ttgaaaaact agagaatact cttatccatg gagaaggaaa ctgcgacttc aaagattgat
     1561 aattttcgtt aggaaatgat agcagtacta tattactaaa atgttttgaa aactccttaa
     1621 actcataatt tatatatcct ttagaaggat ccattatata gaccttattc ttttttactt
     1681 tgtaaataac tacataatgt tgattatccc agaatgctat taatggtaac ggaagttcac
     1741 taattttatt tacatcttta acttgatatg agccagtatc aaaatttcgt ttattcaata
     1801 actgtttcaa gtcacctata ctataaccat ctctcccttt ttctatatca cgtcttaaat
     1861 ctagtaatgt ctctttgctt ttatagaaat gtagtatgga caagcagcaa cataaaccac
     1921 attctatttg agacatttgc tcaatattag gtacttttct agtcatcatg tcctcttaac
     1981 tccagtaata aaacattaag taatctatca tcttgttttc gagatatttc atagacaact
     2041 ccagatactc ctagcataaa agaaaatgta ttcatagtat tcaaatccgt acttaattct
     2101 ggtttgataa cctgagaaac gacattatca aaataaaaat ctatagattc ttttattaat
     2161 aggttttctt catctttcaa tattgcatca agacaactga tagtacctac agaaccgtga
     2221 cataaattca attctcttat tttttctaca ttagttaata cattttcaat tattgataaa
     2281 tcattattcc caatattagt tttatcgaaa atttcttttc tagctaataa aatgcccgga
     2341 gctccataac accaaaaatt aggaaaggaa tcattatgat ttcttcatat gtctttccaa
     2401 ttttttaata tattattgaa acatttatct tctttatata gtaattcctc tatacatttt
     2461 aatatatctg tactaggatt aatttcataa taatatgata attacattgc tactccagaa
     2521 taatcgtgtg ctaaacctgt tactgttata ttatctaatt gtgaaataca ataattaata
     2581 cactttttta aatgatgata atatccatca ccaaaaccaa aatcggtaaa aattttgaaa
     2641 ttttcttcat acttggactt cctttccgtt tttatttatt gtacaataaa taaaaacgga
     2701 tttaattttt gttgggaaaa tgggaaatta tgaaatcaaa acttggcatc acacttagaa
     2761 aagttcgtaa aggaaaacaa attagtctat gctctgtagc agatgaacat ctttcaaaat
     2821 cacaaatatc tcgttttgaa cgtggggagt cagagatatc ttgtattcga ctaatcaata
     2881 ttttagacaa attacatatt actttgtagg ggagtttttg gctatcgttg ctcaattgtc
     2941 tgattaaggt cctacccttg atgaaacaat tattatccat gttttcttta ttatagacaa
     3001 agtaagaaga cgtttctcga atgtagactt tatatttttt atgattttct tcttccataa
     3061 tatccaattg atagttggga atgaaaataa gaccgctctg tttgacaccg aaagacacct
     3121 tgatatagac gcccttatca actagcttct ctatttggtt ctctgcaagt tccacttcaa
     3181 attcacgaac ggtatctcat ttttccttaa atgtcttaaa ggcttcctca atctcttcag
     3241 tggatacttt atccttatct cgttcttctt ggaaagcatg gtactgttcc tgtaaattct
     3301 ctaatccttc tgaagcaacg acttccttat ttttaaaata atcttgaaaa aatttgacat
     3361 catataattt cttatcactt attttttgat gacccaaact tatcttttga ttattttctt
     3421 ccaggataaa agttacattt tttgttttaa gtcaatggtt agattcaatt cttttgcttt
     3481 tgttattaaa tcttctaaag aattgacacg gtttaacaaa aattctaaac gactttcaat
     3541 ctcttgctta gcaaaatgcg ttctaaaaaa ttcttcatca tatagatctc gtttgctgag
     3601 ttggcgccct cgaattggtt ttatcatcgt tctatctgtc atcaaaaaac ggctatgctt
     3661 ttgactaaaa tcaatctgaa catgcaactg ctttgctttc tctaaaaaat catcaaacga
     3721 tttagattgc tgaagcaaaa aataaagacg ttgtttcaat tcaaatttat gactagattc
     3781 cttatatttt ttataatctc gaaaagatca ggatttttag ctaaaactgc cttacgaaaa
     3841 tccttccaga actgatggtc aatctcatta gccacatcca aacgccaagc atcgatatta
     3901 aactcttcaa tccaataagt cgcaaccttt aaaagataat tcttgacctc tggattggct
     3961 gtatttagct taggcatata gtcctcgaaa ccaaaaacat gatagggtaa gtctctctta
     4021 ttaactagct tttcagttgt caatgggaat tgttgaatat ggaaccaatc cttataagca
     4081 gactgttcac catttttgac gacatttttt cattgaagag attgcgaacc aatatgatta
     4141 aataccgcat ccagcatgac tttcatgcca cgatgatgcg cttgatccac cagttcccga
     4201 aaggtctcct tgtctccaaa ataacggtca atttcaaagt aatctgtcgt attgtacttg
     4261 tgattacttg tagattcaaa gatgggacaa agatatagtc cagtaatacc caagtcttgc
     4321 aagtaattca tatgatcaat aatcccctgt aaatcaccac caaagaaatc atcgctctta
     4381 ggtgtgacag atgaatccca gtctaaagtc ccttctgggt ttaatagagc attgccattg
     4441 gcaaatcttt caggaaatat ctgataccat accgtatttg aaacccagtc aggaaccttg
     4501 caggcatcaa tctcatgaag ataaggcaac ttaaatccat tcccaattgc atgaagattt
     4561 tctagagaat tttccacaca ccctttatcg ccatacaaaa tattttgacc ttctgtatct
     4621 ctgagctcaa agagatactg gatacgtgca aagtcaactg acacttcaac ctgccaatgg
     4681 tcaaataagg taccagaagt tatcttgacc atttcttttg tatcctgata aaactcttcc
     4741 ataaagataa aagggtcccc atagtgcaag ttgatgcttt caatgtcccc tttcttagtt
     4801 cgaattcgaa tatggagttt cttatcctta taaagatagg catactccga ctcaggccta
     4861 tggtaaatag cactcaattc catcaatttg tctcctaaag tattcattca aattttacgc
     4921 aaacgttttc aaactcaata aatccagtat actatttttg taaactattt gcaaggaatg
     4981 tccgttgtta aaggaactat cttttaaagt atacaaaaag ccttaaaaaa ggctttctct
     5041 atatactaat cctctttcgg ttttgaaaat acttctactc gctgagctag gactttgatt
     5101 tctacaggta ggttatctga tttatctccg tcaacatctg actccaattc actatctgaa
     5161 gagattttaa tattacgcgc tttgatatac tcgatattat catttgcgac aacatcccct
     5221 tttaataaat caggaatgac ggataatttg gagaatatag aggcatcttt cagaatcaaa
     5281 atgttggcat agccgtcctt gttttcttca aagattttct tatcagcgaa gtaatttgtc
     5341 aaaaggacca aaacatggct agcttcacca acataatttc cattttctgt ctcaacctta
     5401 atgttaaaga cctgatctgt catgacagac ttcatggtat ttacagcata ggttaaaata
     5461 ccgaattttg ttttgtcctc tatttcaaca ttgtgaatcg cctcaggcag agaaccgata
     5521 ctaaagatat aaccaaaata gttgtcattt gctttaccga tatcaatctt attggttaaa
     5581 tcaaaatcca gttcgtcaat tgcgccatcg atgtcttgat tgatttccaa aagttttgta
     5641 atgaggttac ccgtaccgcc tgggataatc cctaacttag gaatgtagtc tctctcatca
     5701 atacctgaaa tgacttcatt gacagttcca tctccaccaa acacaaccac tgcatcatac
     5761 tgctcacgag aagcttcttc agcaaaatgt gttgcatcca gcgctttttc ggtaattttg
     5821 gtttcaacat attcaaagta ttcttttgct ttattctcca gcttttcttt gtaatccaaa
     5881 gccttctcgc caccagaagt agggttgata attaccattg cttttttcat tgattttatc
     5941 cttaatttta aacagaaatg tttacatttc gtcgtatgca agtaaatgta atcctattat
     6001 acaatgaaaa tacagaaaag agaaatctga cgtactggag attaatacgc ttttattcta
     6061 ttttcccatc gcctaactac atcctttaag ggttcatcca agtaagaata ggccttatcc
     6121 ttgatccaat caggaatacc gtaagctgcc tctgctatgt tacaagtgat tgctgcgaga
     6181 gtatcactgt cgccaccaag tgagatggca tttcttatcg catcttcgaa gtctctactt
     6241 tcaagaaagg cgataatggc ttgagggaca gtttcctgac atgtttcgtt aaaacgatag
     6301 ttaggacgga tttcatctaa agtttgagat agattgtaat cgtattcttt ttctatataa
     6361 tccttaattc gtcttttaca ctctgtaaga ttgtcgttaa ttgattgctc gtactctcta
     6421 caataaccac caaagtaaaa acgacataga aagatagcat cagctgtagc catagcgcct
     6481 ttgacacctt ctggatgatt atgagttacc tctgcagaaa gactcgtaag tcctctagat
     6541 gatggccata taccagtttt cgcataaaaa ccacagtcca tgatccaagc acatggagaa
     6601 atacgcatag ctgatccatt cccaaagcta ttataaggct cacggttatc gctgtttagc
     6661 catgcattaa accgagcacc gtaatcagca ttcggataca ttctgccata tttcttcatc
     6721 gcgtcaatga aatcgtcttt ttgtccacca ttcataattg cttctgcaac agcacaggtc
     6781 ataaccgtgt catctgtaaa aaagcagtcc ttccgaaata aaggaaagtc ctttgttttg
     6841 atattgttcc attcgtaaac agaaccgaca atatctccaa taattgctcc aagcatcaga
     6901 ttcctccttg ttcattttga tgctttttat attggttata taccatattt attttagaaa
     6961 acaacatcct gttggatttt aaaaatttca tttttttcaa aatagggttt taccatttct
     7021 ttccacctag ctctatgaaa attgattgat tttaaaggag atagggcata atttcccaat
     7081 gcataaccat catttacttc aacaacaagt gttctgccat cgcgagtaac accgatatct
     7141 agtccataag ctattggcgc atctttccaa catgatatcg cttcatcaat tacacttgca
     7201 tcaaattgtg catgataatc acctgtatag ggtcgaacat ctaatacgcg accatctaac
     7261 acaaaacaac gccattcagc tatgaattct acaacctcac taatccatat aggatagtcg
     7321 aaaggtagac caatacctat taaatcatgg gttccattaa caactcttcc agtaaagact
     7381 tttgaaccag ctttaggctt aataaatttt ccccaattat caggtatatt cacaatctct
     7441 cctaaaatac cagcataaat ctttcgacca taaaactctt taagctcaat aggatagtca
     7501 taaaccggaa cgtttaagcc catcattttt agtaatgctc tagtctccat tatataatct
     7561 acaactatat cttcacttgt taactctttt atttcagaaa aagattgata taaaataact
     7621 tcttctcctt gtaagtaggc acctacttga gcattgtatt tattaattga aacctcactt
     7681 ggtaatttac tttgtctaat ataaacaacc atttcatcac tcctatatca ctagtgttac
     7741 actgatttgt aaaaaataat agcaattttg ctcttatttt tttgagtaaa tagctcccat
     7801 aatatcatcg aaataatcaa cggtatttag gagtaattca ataacctggg actttgttag
     7861 tcgcattccc cttctatctc tagcatcttc tactaaattt tcaagtttct ctagattttt
     7921 atcatccaag ctaatcatta ttctattttt atcggttgcc attttcatca cctcaagtta
     7981 attctatcac aggtgtaaca cttgtgtcaa ctggctttta taatacatta gtttaaaagt
     8041 ggagaggatt tttaacacag taactttaaa tctttggtat taaaaaattt tcacaatatt
     8101 tatagaaata aaatctgtct caaatcagtt atcaaatcta gtataaatta tgagcggcta
     8161 ctctaatact ttccctctaa acaagaaaaa gacttacact caaggatttt cttccccccc
     8221 ttcgttataa cgttttgact cttttactag caaaggtata tactcacaag gaactttggt
     8281 tgactattga atctctccaa cttcttcttt aacatatcct tctacatctt caatctctac
     8341 aaacattggg tctaagtgac acaagaaatg ccaaacttcg atcccttttt ttctgtaaag
     8401 aatcgcttca ccgtcttcac ttccgaaaaa gcttctgtcg atttcatatc cgcggctttc
     8461 taagaagtct tttgctttac gatagttcgt ttctcttgtt tcgacatagg ttttaacttc
     8521 atggttgtta acgacatatg catcaatttt tgaatatcct tcgatcactc tatcattttt
     8581 gagggataaa tttgaaatct ctttccaaat aatgtttaca ttttcctcag gatcgaacat
     8641 aaatttagat aaaggaacaa tatttccgtt aaaaataatt tccatataat ccggtatgtt
     8701 tttaggatta aaatactcca cttcaaaacc atcttctgtt tccagagtgt atcccgggat
     8761 ttgagctaca aaggctttcc catcttctat ggaatcaaat gctactaaat ctttagaata
     8821 atcattttgg tacaattcca atataaccat cgataatctc tccattttca ttatcaggct
     8881 aatgtaaata agcacgtcac ctgaccaatt caggctctct gtatcatctc atcatatttc
     8941 ctacttactt tacgagtcct atacccagaa cacaccttat cgaccttcgg tctcacctcg
     9001 ttgcattggc tgaacatcta cttttacttc gctgatgctt caactcgtac aagcagtgat
     9061 accgcctcag cgtgatgcgt cagtgggact caaaaggttc ggggaacctt ttgaggatta
     9121 actacgtttc tctaataaac ttacacattc aacttgttca tcattgtcca aacctatgtt
     9181 gagattttct tctataattg gtagcttaaa agtaatggat tttagccatt gtccgttaga
     9241 ttgtttttct tcataaactt gaatttcaga aatcaaagct gaaattaact gcctacgctc
     9301 tacatcattc atgactttat agagcttatc aaaatagatc agaaccttat atatgttatc
     9361 tcctgtaagc ttttcagctt caatagtctg tttctttgct ttcgcatcaa ttagtgatga
     9421 ttctaattca tctactttgt catacatacg atatagtcta tcatctaaat cctgtttcct
     9481 tctcttataa tgcttatctt caacatctaa attatctatt tcctcaatta gcttaaactt
     9541 tgtagaatga ctctttctca attccttttg gtaattatct atttcttttt ctatttcaga
     9601 ggtatccacc ttcatgttga ttttttcttg catcatagaa gcaaatttcg gattacttac
     9661 tatcttgaca atcacctctg caacagcatc atctaacaat tcttctctaa tttgcttact
     9721 gaatgtacac ttatgacctc ttatcatctg cctatggtta caaccatagt aataaaaatc
     9781 tttatacttt gtgccatctt tctttttctt gatacacttg ttcccaaaca ttcccactcc
     9841 acatatcggg cattttacaa ttccagaaag caagtgtgtg cgtgtatctt ttcctttatt
     9901 cacatgctca tatttctttg cttgagattt tagcttaacc tgagcagctt gccaaacttc
     9961 atcggaaact atagcttcat gtatcccttc agatattaga tattcatctt gttcaacctg
    10021 cttatattca tttcttgtac catgaacttt ttctaaagtt cttcttccaa atgctatttt
    10081 cccattatat acaggattct ttaatatctt tcttataaga cctgcatcaa acaaaggatt
    10141 cttaccattc tgtcttggga tttttctaat tccatgattc tctaagtatt tagatatccc
    10201 attggctcct atcgtagtat ttacatactg gtcgaaaatc gttcttattg caactgcctc
    10261 ttcctcattt ataaacagct tgccgtcttc aagtttatat ccatacggag caaagccacc
    10321 attccatttt ccttcccttg ctttttgaat gcgaccttcc attgtttgaa tacggatgtt
    10381 ttctctttct atttcagcca cagctgataa aacagaaatc attagtttcc cagcatcttt
    10441 agatgaatca atgccatctt caacgcagat aagattaact ccataatcct gcattatctg
    10501 aagtgtagaa agaacatcag cggcatttct tgcaaatctt gataacttaa acacaagaac
    10561 aaaagatact ccatcttttc cagattttat atcttccatc attcgattga actgtattct
    10621 accttcaata gacttgccag acttcccggc atcttcatac tctccaacaa tttcataatc
    10681 gttgtaaata gcaaaagctt tcattcgtga tttttgtgcc tctaacgaat acccctctat
    10741 ctgtattgac gtagatactc gtgtatagag gtatactttt attttttctt ttgacatagt
    10801 attaatctca atataatttt tctatatcat atataatttt tttaatttaa gtttggacta
    10861 tcatttcaag tatattataa cacttttatt agtccgtctc aatttgtgtt tttgccatgt
    10921 caaaactatt tttcatctct tgattttttg ctggcgttgg atcgggtaga ttatctaaat
    10981 ctaaagcacc agcatatttt gcaatcagat ttgctattaa atcagccaat ccattccagt
    11041 cattgtccaa tatatacctc ctctaaagtt ttatatctaa taattatttg tttaattaag
    11101 ttttttgaca ttgacaagtg ctttggatta gcaacatagg aatctcacct ccgcctctat
    11161 tccggatgag ccggcttcaa ccttagaagt atcattatcc tcattttctt catagcggat
    11221 agggtatccc tccctatatt caaactctta cttatcgctc actttctttt tacttagcag
    11281 aacttttttt gccgaattat tcagccgaaa gatcttgacg gataggttat tacgctccaa
    11341 aaataattaa cgtcttgtct tggtctattc aattgttaag gttcaaaatt tatcgagagt
    11401 tattaatctt tttaaaattt gaccatcaga aaatatttat cttaatgtaa caaaattcta
    11461 taaattaccc tcttatactt aacagtgaaa agaagtcttt cttggtaacc aattttgaaa
    11521 tagaatttgc ttatataaaa aggtcaaatt cccactgcat aagtagcagt gaaaattaga
    11581 ccctcttggt aactgtcatc taaaagtctt ctagcatttc tttaattttc taatcgcctt
    11641 taaagtgtca tatttatatt tttttatctc tggcatactt tgataccttt ttagacttaa
    11701 agtctttaat agtgcctttc cacctctttt tatctataaa gattctccta catcataatt
    11761 cattttttta tttaaacctt tctgtcttag tttgtcttta tcttcttcat accattttaa
    11821 gattgtcaca tagtggtttt gataggtctt accactgctt tccatgtatc tggatagttt
    11881 atttatcatt atatctgtgt gtgagtttaa tttttctttt agatttttat attcttcttt
    11941 gcttaacctt acatttttga attctccata aaaaatgggg gtggactttt tatctatctc
    12001 tccctctctc tctttatcta tctctatatc tttccatgta attccaatct ggagtacctc
    12061 tactgtctat cggtaattta attttgatat ctggcaatac tgtgctagat atttgatctt
    12121 tatattcagt attttttaaa gcttgcctaa taattgaagt taaatagaat gctacttctt
    12181 tattcaattc tttatttttt aattttaaac aatgaatttt catatctagg cttgctttat
    12241 atttatgata aaagactgct cctaaaaatg aaacagatat aaaattttca aaaactctat
    12301 aatttttatc atctatatct tcgtagtaac ctaagatacc attgtcaata tttgtagcac
    12361 taattctagg agtttttcca tcgagtaaat atctttttgg aatagatgag cctgttggta
    12421 cttgactcga tttccccttt ttttcggtaa taaatatttc tttttatttt gttgtctgat
    12481 atttttccta cctgtccttt gtaggatgag tattttctag attttcttga ataacttttt
    12541 acttgaagtt ttagcttttg aactagtcgt tgtactttct ttttgtttat tatcagtcct
    12601 gatcttttta atattgctgt tattctctat atcctatttt tcattcatga tattctttta
    12661 ctaattttat cttaaattct gtgctgtatt tgccattaaa aaactgacct cctttagtta
    12721 gttttttggc ctaacttttg agggtcagtt caaaatttgc gacttttaaa tgaattccaa
    12781 tattcaatta ttaagagcta acatggtgct tgccaatagg aatcattaga ggcgaattgg
    12841 aaatagggtc acgtataatt tttgcttcaa gattaaagat atctttaact agtttatcat
    12901 ttagtatatc ttcaggcttt ccctctgcaa caagtttacc ttctttaatt gcaaataggt
    12961 aatcagcgta tcttgctgtt agatttatat cgtgcaaaat catgcaaatg gttgtcttat
    13021 atttttggtt tagatcagtc aagaggtcta atagttctat ttgatatgag atatccaagt
    13081 aagtagttgg ctcatctaaa agtaggatac ttgtatcttg ggctagggct agagctatcc
    13141 atactctttg cctttgaccc ccagaaagtt cttcaactag gttatttgct agatcttcaa
    13201 cattggcctt aaccattgat ctgtttatta tttcaaggtc atcttttcca agactcttaa
    13261 aaggctttct gtaggggaaa cgaccacggc ttacaagatc agctactgtt attgattcag
    13321 ggattattgg agattgaggt aatatagcta tgtgttttgc taaatctttt tctttataag
    13381 aattaattga tttattatca agcaatactt ctccctctaa tggctttata agtcgagaca
    13441 aggttttaat gagtgttgat ttcccacaac catttgaccc aataataact gatatttttt
    13501 cttcaggtat ttttatattt atattttcca agattatttt ttcatcataa ccgcaggtaa
    13561 gattatttga ccacagacct ttcattatat attcctcctg ttcattttta ttagtaagta
    13621 tattaagtat ggtgaaccta acaagccagt tacaacacct actggatatc tagctggtaa
    13681 aatattttga gagaatatgt ctgataacaa aactagtaaa attccaacca atccagctaa
    13741 tattgggctt cttttcttgc caatatttaa ggctatggga ccagctaaaa aagatataca
    13801 agctattggt cctgtaattg aagtagaaaa agcagttaaa gatacagcgc aaaaaattaa
    13861 aacaagcctt gaaagctcgg gatttgctcc aagtccgatt gctatttctt caccaagttc
    13921 aataatttct agtcttttat taaaaaataa aactaatata gtagcaataa tacttactat
    13981 tagaacaaga ggtatgtcat ctaactttgt aaaagataaa gagccactga gccatctcat
    14041 aacttcttgt aattcatatc ttgctacttt caacaataaa aatgaggtgc ctgctcttgt
    14101 gacagcttga aaaccaatac ctaatattat cagtcttgct gctgaaaaac catctttttt
    14161 agctagtaaa aataatatta aagatgatgt tagtccacaa gttattgaaa taattccagt
    14221 agttaaacta tttgttttta ataccaatat gcaaaagacc gctgcaatag atgaagaact
    14281 tgtgacaccg attatatcag gacttgcaag aggatttctt aacatagttt gaaagataaa
    14341 tcctgccaat ccaaaagacc agccagctat aattcctgct aataattttg gtaatctaat
    14401 ttccataatc gaaaaactag ctccaggaac agtttcacta tttaagactt taatcaaagt
    14461 tgaaaaagaa taactttcat ctccgataag taaaatgaaa aatgatagac tgattattat
    14521 taataaaaat agtgaggaaa atagtgttat tctatttttt cttttttgaa tacctataat
    14581 taaattttgc attagttatt aacccctcta tttttcatag ttacataaat aagtactgga
    14641 cccccgatta ttgcagtaat tatccctact tcaatttcac ctggtttacc taacatacgg
    14701 ccgattatat cacatataag caagagctct gcacctataa aagatgaaga aatggtcatt
    14761 gtgcgtatat ctttgcttat aaataagcca caaaagtgag gaactataag acctacgaag
    14821 ccaataggtc caccaattgc agtaatactt gaacataaaa gcacacttgc aattattgca
    14881 agtgatctta tcctattaac attaactcca agaccaacag ccatttcatc acccatagct
    14941 aaagcgttta aatctgatga aataaatata gctatcaagt gacctaaaat tataaaaggt
    15001 agtagtgtag atatagaaga taatgtagct gctccaaggc tacctatttg ccaaaatcta
    15061 aatttgtcta agacgttatt attcggtaaa attaaaaaac ttacaaaact gcttaaagcc
    15121 atactaacac aagttcctga taaggctagt tttatagggg taaggcctgc ttttccgctt
    15181 acagcaatcg cgtatacaaa aattgcactt actaagccac caatgattgc aaaacttata
    15241 tggcttatgc ttgatgaaat tcctaaaaaa gaaagaccaa ttactacact aagacttgct
    15301 cctgtgttta taccgagtat acctggatca gctattgggt ttctagtaac tgattgcatc
    15361 aatacaccgc ttatggcaag actagaacct gctaaaattg caaaaatagt tctaggtatt
    15421 cttttatata taattgattt aataaaatca tcatttgtat tgcccattcc aaaagttgct
    15481 aaaaaatctc tgatattaat ttcttttgtt ccaagcttta atgacaaaaa tattgtaata
    15541 agaagaccta ggcagattac aaaaattatg cctaggttta tttgtttttt atttcgcatt
    15601 tttgcatgca tttcctaaaa gatttaggta ttcttcaata gtatagttta ttgaaagtgg
    15661 tgttggagtg catgaggctg ctaacggtgt attatctgga attacagcaa cggcaccatt
    15721 tttaattgca tttattttac ctaaaagagg atctttttgt aaagcttcaa gagttttatc
    15781 atcaccataa gttatgatta catcagcatc atttatctta tttgcttctt ctgcagaaat
    15841 ttcctttgca aaactatctt cactctcaaa ttcttttaat gattcaggga aaactagacc
    15901 taaatctgtt aaataatttg ctcttggatc tttgctagta taaatccaga attttgatgt
    15961 atctgcagca ttaatcatag taaataatac tttttttcct ttgatttttc ctttgatttc
    16021 tggatgtttt tctaattctt tggatatacg agcttcagta tttttgatta actcatcacc
    16081 ttctttttcc atacctaagg cttttgaatc aattttaatc atatctctcc ataaagtttg
    16141 ccaaggttta gatttgtatg ctgctacagg agcaattttt gatagagtgt cataatcttc
    16201 tttagttata ccagaataac ctgctaagat aacatctggt ttagaatttg atattgcttc
    16261 aaagttaagt ccatccaaat cgtcaaatag gttagcttta ccatttagtt ctttgatttt
    16321 ttcttctgtc catggtaaaa ctcctttatc agcacttaca ccgtaatttg cttttgaaaa
    16381 tccaacagga actattccta aagctaatgc tacatcatga tttccccaag caatagttgc
    16441 aactctttca ggttttttat ctaatatagt ttgaccgaaa gcatgatcta aaactatttt
    16501 atcaggcgca tgctctttag aagtattttc ttcattttta acagaattag aagaacaagc
    16561 gctaaaaact atacacatag ctaaaatagc tattagaaaa aatttgtttt tcataaaaac
    16621 tccttaaaca tatttcaagt ctattgtatc gataataatt atcattgtca atagatacag
    16681 ttacaaattt aataatataa ttttttcaaa aaagg
//
LOCUS       DAVBDR010000045        16647 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.045, whole genome shotgun sequence.
ACCESSION   DAVBDR010000045 DAVBDR010000000
VERSION     DAVBDR010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16647)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16647)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16647
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.045"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            63..527
                     /locus_tag="VQ540_001541"
     CDS             63..527
                     /locus_tag="VQ540_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001146193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase"
                     /protein_id="HET2545322.1"
                     /translation="MGGHPGFNCLLLDDEVYEDYYLEFEKEEICSVPRPFPETGMLDF
                     QDRSPWLEGQKEIDLSYDLFSTDAVTLDELQSRTIALRSLKHDKGLKVHFAEFPNLII
                     WSTLNKGPFITFEPWSGLSTFLEEGDHLEDKKNVCLLEANQVEELGFEIEVL"
     gene            685..1110
                     /gene="lacA"
                     /locus_tag="VQ540_001542"
     CDS             685..1110
                     /gene="lacA"
                     /locus_tag="VQ540_001542"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HET2545323.1"
                     /translation="MSIVIGADAAGLRLKEVVKDFLEKENFHLVDVTAEGQDFVDVTL
                     AVAAEVNKEEQNLGIVIDAYGAGPFMVATKIKGMVAAEVSDERSAYMTRGHNNSRMIT
                     MGAQLVGDELAKNIAKGFVNGKYDGGRHQIRVDMLNKMG"
     gene            1141..1656
                     /gene="lacB"
                     /locus_tag="VQ540_001543"
     CDS             1141..1656
                     /gene="lacB"
                     /locus_tag="VQ540_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HET2545324.1"
                     /translation="MRIAIGCDHIVTDEKMAVSEFLKSKGYEVIDFGTYDHTRTHYPI
                     FGKKVGEAVTSGQADLGVCICGTGVGINNAVNKVPGVRSALVRDMTTALYAKEQLNAN
                     VIGFGGKITGELLMCDIIEAFIHAEYKPSEENKKLIAKIEHLESHNAQQTDANFFTEF
                     LEKWDRGEYHD"
     gene            1667..2596
                     /locus_tag="VQ540_001544"
     CDS             1667..2596
                     /locus_tag="VQ540_001544"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HET2545325.1"
                     /translation="MILTVTMNPSIDISYPLDELKIDTVNRVVDVTKTAGGKGLNVTR
                     VLSEFGDSVLATGLVGGKLGEFLVEHIDDQVKKDFFSIQGETRNCIAILHGDNQTEVL
                     EKGPEVLEQEGQDFLEHFKKLLESVEVVAISGSLPAGLPVDYYASLVELANQAGKLVV
                     LDCSGAALQAVLESPHKPTVIKPNNEELSQLLGREVSEDLEELKEVLQESLFTGIEWI
                     IVSLGANGTFAKHGDTFYKVDIPRIQVVNPVGSGDSTVAGISSGLLHKESDAGLLIKA
                     NVLGMLNAQEKMTGHVNMANYQALYDQLIVKEV"
     gene            2598..3578
                     /gene="lacD"
                     /locus_tag="VQ540_001545"
     CDS             2598..3578
                     /gene="lacD"
                     /locus_tag="VQ540_001545"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HET2545326.1"
                     /translation="MALTEQKRVRLEKLSDENGIISALAFDQRGALKRLMAQHQTEEP
                     TVAQMEELKILVADELTKYASSMLLDPEYGLPATKALDEKAGLLLAYEKTGYDTTSTK
                     RLPDCLDVWSAKRIKEEGADAVKFLLYYDVDSSDELNQEKQAYIERIGSECVAEDIPF
                     FLEILAYDEKIADAGSVEYAKVKPHKVIGAMKVFSDPRFNIDVLKVEVPVNIKYVEGF
                     AEGEVVYTREEAAAFFKAQDEATNLPYIYLSAGVSAKLFQDTLVFAHESGANFNGVLC
                     GRATWAGSVEAYIKDGEAAAREWLRTTGFENIDELNKVLQTTATSWKERV"
     gene            3812..4648
                     /locus_tag="VQ540_001546"
     CDS             3812..4648
                     /locus_tag="VQ540_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HET2545327.1"
                     /translation="MYRILNPMNHNVSLVRNDKGEEVIVIGKGIAFGKKKGDLIAENH
                     VEKIFRMKTEESRENFMALLKDVPLDFITVTYEIIDKLSKKYHYPIQEYLYVTLTDHI
                     YCSYQALIQGRYKDSNLPDISAKYPVAFQIANEAFEIYRQKLADHFPEDEIIRIAYHF
                     INAEGENEVELVESIDKRKEILRNVEEVLTDYAIQRTKKNNHFYDRFMIHLNYFLDYL
                     DRSRDDNQSLLDMEDHIKQSYPKAFEIGSKIYDVITQHTGLDLYKSERVYLVLHIQRL
                     LS"
     gene            4684..5001
                     /locus_tag="VQ540_001547"
     CDS             4684..5001
                     /locus_tag="VQ540_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HET2545328.1"
                     /translation="MNREEVTLLGFEIVAYAGDARSKLLEALKAAEAGDFEKADALVE
                     EAGSCIAEAHHAQTSLLTKEASGEDLAYSVTMMHGQDHLMTTILLKDLMHHLIELYKR
                     GVK"
     gene            5003..6697
                     /locus_tag="VQ540_001548"
     CDS             5003..6697
                     /locus_tag="VQ540_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001037357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HET2545329.1"
                     /translation="MDKLIIFIEKGKPFFEKLSRNIYLRAIKDGFISSMPAVLFSSIF
                     ILIAAVPNIFGFKWSDEQLAFILKPYNYSMGILALLVAGTTAKSLTDSVNTRSMEKTN
                     QINYMSTFLAAVVGLLILAADPIEGGFANGLLGTRGLLTAFLAAFITVNIYKVCIKNN
                     VTIRLPEEVPPNIAQVFKDVIPFALSVLSIYGLDLIVRNIFGTNVAESVGKILAPLFS
                     ATDGYIGLAIVFGAYAFFWFVGIHGPSVVEPLIVAISYANIEANVQLVQAGMHADKIL
                     NPVTQTFVVTMGGTGATLVVPFMFMWLCKSKRNRIVGRASVVPTFFGVNEPILFGAPI
                     VLNPIFFIPFVTAPIINVWIMKFFVDVLQMNSFSIILPWTTPAPIGIVMGTALAPLSF
                     VLAITLIIIDTLIYYPFVKVYDHQILEEERSGKSNDELKEKVAANFNTAKADAILEKA
                     GVDAAQNTITEETNVLVLCAGGGTSGLLANALNKAAAEYNVPVKAAAGGYGAHREMLP
                     EFDLVILAPQVASNFEDMKAETDKLGIKLAKTEGAQYIKLTRDGKGALAFVQAQFD"
     gene            6906..8312
                     /gene="lacG"
                     /locus_tag="VQ540_001549"
     CDS             6906..8312
                     /gene="lacG"
                     /locus_tag="VQ540_001549"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HET2545330.1"
                     /translation="MTKTLPKDFIFGGATAAYQAEGATHTDGKGPVAWDKYLEDNYWY
                     TAEPASDFYNRYPVDLKLAEEYGVNGIRISIAWSRIFPTGYGQVNAKGVEFYHNLFAE
                     CHKRHVEPFVTLHHFDTPEALHSNGDFLNRENIEHFVDYAAFCFEEFPEVNYWTTFNE
                     IGPIGDGQYLVGKFPPGIQYDLAKVFQSHHNMMVSHARAVKLYKDKGYKGEIGVVHAL
                     PTKYPLDPKNPSDVRAAELEDIIHNKFILDATYLGRYSAETMEGVNHILSVNGGSLDL
                     REEDFTALEAAKDLNDFLGINYYMSDWMEAFDGETEIIHNGKGEKGSSKYQIKGVGRR
                     VAPDYVPRTDWDWIIYPQGLYDQIMRVKKDYPNYKKIYITENGLGYKDEFVDNTVYDD
                     GRIDYVKQHLEVLSDAIADGANVKGYFIWSLMDVFSWSNGYEKRYGLFYVDFETQERY
                     PKKSAHWYKKVAETQIID"
     gene            8355..8537
                     /locus_tag="VQ540_001550"
     CDS             8355..8537
                     /locus_tag="VQ540_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000471575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3884 family protein"
                     /protein_id="HET2545331.1"
                     /translation="MFKDFIQSIYEKVYIINFEKCSQIPCLTSEELKSLFLNFINPEE
                     WDTISFDSDFMPFQQS"
     gene            complement(8815..9576)
                     /locus_tag="VQ540_001551"
     CDS             complement(8815..9576)
                     /locus_tag="VQ540_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000917571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HET2545332.1"
                     /translation="MLKQEKLAKILEIVNSKGTITVKQIMDEIAVSDMTARRYLQELA
                     DKDLLIRVHGGAEKLRTNSLLTNERSNIEKQALQTAEKQEIAHFAGSLVEERETIFIG
                     PGTTLEFFARELPIDNIRVVTNSLPVFLILSERKLTDLILIGGNYRDITGAFVGTLTL
                     QNLSNLQFSKAFVSCNGIQNGALATFSEEEGEAQRIALNNSNKKYLLADHSKFNKFDF
                     YTFYNVSNLDTIVSDSKLSDSILFKLSKHIKVIKP"
     gene            complement(9758..10720)
                     /gene="nrdF"
                     /locus_tag="VQ540_001552"
     CDS             complement(9758..10720)
                     /gene="nrdF"
                     /locus_tag="VQ540_001552"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HET2545333.1"
                     /translation="METYYKAINWNAIEDVIDKSTWEKLTEQFWLDTRIPLSNDLDDW
                     RKLSNKEKDLVGKVFGGLTLLDTMQSETGVQALRADIRTPHEEAVFNNIQFMESVHAK
                     SYSSIFSTLNTKAEIEEIFEWTNTNPYLQKKAEIVNEIYLNGSPLEKKVASVFLETFL
                     FYSGFFTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEEEQEKLK
                     EWMYDLLYTLYENEEGYTESLYDGVGWTEEVKTFLRYNANKALMNMGQDPLFPDSAED
                     VNPIVMNGISTGTSNHDFFSQVGNGYLLGEVEAMQDDDYNYGLD"
     gene            complement(10908..13067)
                     /gene="nrdE"
                     /locus_tag="VQ540_001553"
     CDS             complement(10908..13067)
                     /gene="nrdE"
                     /locus_tag="VQ540_001553"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000523276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HET2545334.1"
                     /translation="MGLKHLEDVTYFRLNNEINRPVNGQIMLHKDKEALDAFFKENVV
                     PNTMVFDSIKDKINYLIEHNYIETAFIKKYRPEFLEELAQFIKDQNFQFKSFMAAYKF
                     YNQYALKTNDGEYYLENMEDRVFFNALYFADGNEAVAIDIANEIIHQRYQPATPSFLN
                     AGRARRGELVSCFLIQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSTKKENADEKVR
                     VKTLSLGVVVPDKFYELARKNEEMYLFSPYSVEKEYGVPFNYIDITEKYDELVANPNI
                     RKTKIKARDLETEISKLQQESGYPYVVNIDTANRANPVDGKIIMSNLCSEILQVQEPS
                     LINDAQEFLQMGTDVSCNLGSTNVVNMMTSPDFGRSIRAMVRALTFVTDSSHIVAVPT
                     IDHGNSQAHTFGLGAMGLHSYLAQQLIEYGSPESVEFTSIYFMLMNYWTLVESNNIAR
                     ERGITFHNFEKSDYANGSYFDKYVTGEFVPTSDRVKELFKNVFIPGVADWAELRDKVQ
                     EDGLYHQNRLAVAPNGSISYINDVSASIHPITQRIEERQEKKIGKIYYPAAGLSTETI
                     PYYTSAYDMDMRKVIDVYAAATEHVDQGLSLTLFMRSDIPKGLYEWKRENKQTTRDLS
                     ILRNYAFNKGIKSIYYVRTFTDDGGEVGANQCESCVI"
     gene            complement(13148..13366)
                     /gene="nrdH"
                     /locus_tag="VQ540_001554"
     CDS             complement(13148..13366)
                     /gene="nrdH"
                     /locus_tag="VQ540_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000259243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HET2545335.1"
                     /translation="MVTVYSKNNCVQCKMTKRFLDSNNVSYREINLDEQPEYVDQVKE
                     LGFSAAPVIQTPTEVFSGFQPGKLKQLA"
     gene            13717..13980
                     /locus_tag="VQ540_001555"
     CDS             13717..13980
                     /locus_tag="VQ540_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019775469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HET2545336.1"
                     /translation="MASKDFHVVAETGIHARPATLLVQTASKFASDITLEYKGKSVNL
                     KSIMGVMSLGVGQGADVTISAEGADADDAIAAISETMEKEGLA"
     gene            13986..15719
                     /gene="ptsP"
                     /locus_tag="VQ540_001556"
     CDS             13986..15719
                     /gene="ptsP"
                     /locus_tag="VQ540_001556"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HET2545337.1"
                     /translation="MTEMLKGIAASDGVAVAKAYLLVQPDLSFETITVEDTNAEEARL
                     DAALQASQDELSVIREKAVGTLGEEAAQVFDAHLMVLADPEMISQIKETIRAKKVNAE
                     AGLKEVTDMFITIFEGMEDNPYMQERAADIRDVTKRVLANLLGKKLPNPASINEEVIV
                     IAHDLTPSDTAQLDKNFVKAFVTNIGGRTSHSAIMARTLEIAAVLGTNNITEIVKDGD
                     ILAVNGITGEVIINPTDEQAAEFKAAGEAYAKQKAEWALLKDAQTVTADGKHFELAAN
                     IGTPKDVEGVNNNGAEAVGLYRTEFLYMDSQDFPTEDEQYEAYKAVLEGMNGKPVVVR
                     TMDIGGDKELPYFDMPHEMNPFLGFRALRISISETGDAMFRTQIRALLRASVHGQLRI
                     MFPMVALLKEFRAAKAVFDEEKANLLAEGVAVADNIQVGIMIEIPAAAMLADQFAKEV
                     DFFSIGTNDLIQYTMAADRMNEQVSYLYQPYNPSILRLINNVIKAAHAEGKWAGMCGE
                     MAGDQQAVPLLVGMGLDEFSMSATSVLRTRSLMKKLDTAKMEEYANRALTECSTMEEV
                     LELQKEYVNFD"
     gene            15974..>16647
                     /gene="phtA"
                     /locus_tag="VQ540_001557"
     CDS             15974..>16647
                     /gene="phtA"
                     /locus_tag="VQ540_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtA"
                     /protein_id="HET2545338.1"
                     /translation="MKINKKYLVGSAAALILSVCSYELGLYQARTVKENNRVSYIDGK
                     QATQKTENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIFSEE
                     LLMKDPNYKLKDEDIVNEVKGGYVIKVDGKYYVYLKDAAHADNVRTKEEINRQKQEHS
                     QHREGGTPRNDGAVALARSQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKN
                     ELSASE"
BASE COUNT         5221 a         2918 c         3460 g         5048 t
ORIGIN      
        1 aactagaatt ctagttttgc aggaagtcta ataaagaaac tagcaaggtc aggccttact
       61 ttattggtgg acatccagga tttaattgtc ttctacttga tgatgaagtc tatgaagatt
      121 attatctaga gtttgagaaa gaagagattt gctctgttcc acgtcctttc ccagaaacag
      181 gtatgttgga tttccaagat agaagtccat ggctagaggg acaaaaagaa atagatctta
      241 gttatgatct tttcagcaca gatgcagtga ctttggatga attgcaatct cgaacaattg
      301 cccttcgttc tcttaaacat gataagggat tgaaagtgca ttttgcagaa tttccaaacc
      361 tcatcatctg gtcaactttg aacaagggac ctttcattac ctttgaacca tggtctggct
      421 tgtcaacatt ccttgaagaa ggagatcatt tagaagataa gaagaatgtt tgtctcttag
      481 aagccaatca ggttgaagaa ttagggtttg agatagaagt tttataaaaa aagtaaaaaa
      541 taaataacaa aaacaaacac aaactgttga cttcttcaaa caatagtagt atattatgtt
      601 tgtgaggact aattgactgt tttttaaaga cagccaatac actgctggaa tccagcatag
      661 aaaaaataaa aaggagtata caatatgtct attgttatcg gtgcagatgc tgcaggtttg
      721 agattgaaag aagttgtgaa agacttctta gaaaaagaaa acttccacct tgtggatgtt
      781 acagctgaag gtcaagactt tgttgatgtg actctcgctg ttgctgcaga agtaaacaaa
      841 gaagaacaaa accttggtat cgtgattgat gcttatggag ctggtccatt tatggttgca
      901 actaagatca aaggaatggt tgctgcagaa gtatctgacg aacgttcagc ttatatgact
      961 cgtggccaca acaactcacg tatgatcact atgggggcac aacttgttgg tgatgaattg
     1021 gctaaaaaca tcgctaaagg atttgttaat ggtaaatacg acggtggacg tcatcaaatc
     1081 cgggttgaca tgttgaacaa aatgggctaa ttagattaca gtaagaaagg taagttaaaa
     1141 atgagaattg caattggatg cgaccacatc gtaacagatg aaaaaatggc ggtttcagaa
     1201 tttttgaaat caaaaggata tgaagtcatt gactttggta catatgacca tacacggact
     1261 cactacccaa tctttggtaa aaaagtaggg gaagctgtaa ctagcggcca agctgatctt
     1321 ggggtatgta tctgtggtac tggtgttggt atcaacaacg ctgtaaataa agttccaggt
     1381 gttcgttctg ccttggttcg tgatatgaca acagcccttt atgctaaaga acaattgaac
     1441 gctaacgtta tcggctttgg tggtaagatt actggtgaat tgcttatgtg tgatatcatc
     1501 gaagctttca ttcatgctga atacaaacca tctgaagaaa acaagaaatt gattgcgaaa
     1561 attgaacacc ttgaaagtca caatgctcaa caaacagacg caaacttctt tacagaattc
     1621 cttgaaaaat gggatcgcgg agaataccac gactaagagg tgacctatga ttttaacagt
     1681 cacaatgaac ccatccattg atatttccta tcccttggat gagttgaaga ttgatactgt
     1741 caatcgtgtg gtggatgtaa ccaaaacggc tggtggtaag ggacttaatg ttacccgagt
     1801 actttcagaa tttggtgatt ctgttcttgc tactggttta gtgggtggca aacttggtga
     1861 gtttttggtt gaacatatcg atgatcaagt aaagaaagat ttcttttcta ttcagggaga
     1921 aactcgtaac tgtatcgcta ttctccacgg tgacaaccaa acagaagttc ttgaaaaagg
     1981 tcctgaagta ttggaacagg aaggtcaaga ctttttggaa catttcaaaa aactcttgga
     2041 gtcagttgaa gtagtagcca tctcaggtag tctgccagct ggccttccag ttgattacta
     2101 tgcgagcttg gtagagcttg ctaatcaagc tggcaagcta gtagtcttgg actgctctgg
     2161 tgcagcactt caggcggttc ttgaatcacc ccataaaccg acagtaatca aacccaataa
     2221 tgaggaattg tctcagcttc taggaagaga agtttctgag gatttggagg aattaaaaga
     2281 agtccttcaa gaatctttgt ttacagggat tgaatggatt atcgtttcac ttggtgccaa
     2341 cggtactttt gccaaacatg gtgacacttt ctacaaggta gatattccta gaattcaggt
     2401 ggtaaatcct gttggatctg gagactctac tgtggcagga atttcttcag gacttcttca
     2461 caaagaatcg gatgcaggat tactcatcaa ggcaaatgtc cttggtatgc tcaatgctca
     2521 agaaaaaatg actggtcatg tcaacatggc caactatcaa gctctatatg atcaattaat
     2581 agtaaaagag gtataaaatg gctttaacag aacaaaaacg tgtacgctta gaaaaacttt
     2641 ctgatgaaaa tggtatcatc tcagctcttg catttgacca acgtggtgct ttgaaacgcc
     2701 tcatggctca acaccaaaca gaagaaccaa ctgtggccca aatggaagaa cttaaaatct
     2761 tggtagcaga tgaattgact aaatacgctt catctatgct tcttgaccct gagtatggac
     2821 ttccagcaac taaggctctt gatgaaaaag ctggtcttct ccttgcttat gaaaaaacag
     2881 gttatgacac aacaagcaca aaacgcttgc cagactgctt ggatgtttgg tctgcaaaac
     2941 gtattaaaga agaaggtgca gatgcagtta aattcttgct ttactatgat gtagatagct
     3001 cagacgaact caatcaagaa aaacaagcct acatcgaacg catcggttct gagtgtgtgg
     3061 ctgaagatat cccattcttc cttgaaatcc ttgcttacga tgaaaaaatt gcggacgcag
     3121 gttctgtaga atacgctaaa gtaaaaccac acaaagttat cggtgctatg aaagtctttt
     3181 cagacccacg ttttaacatt gatgtcttga aagttgaagt tcctgttaac attaaatatg
     3241 ttgaaggctt cgctgagggt gaagtggttt acacacgtga agaagcagca gccttcttca
     3301 aagcgcaaga tgaagcaacg aacttgccat acatctactt gagtgctggt gtatcagcta
     3361 aactcttcca agatactctt gtatttgctc atgaatcagg tgcaaacttt aacggagttc
     3421 tttgtggtcg tgctacatgg gcagggtcag ttgaagctta catcaaagat ggtgaagcag
     3481 cagctcgcga atggcttcgc acaactggat ttgaaaacat tgatgagctc aataaagttc
     3541 ttcaaacaac agcgacttca tggaaagaac gtgtgtaaga aagtcctcct agtttaggaa
     3601 catgaatcta aaaaaattta aaaaaagttg tatgtaaagg tttacaaaat aacttacttg
     3661 tgctatactt aaatcacaag ttaatacaag gtgagtgtta ctaagtaata ttaggcatga
     3721 tcacaggtga attagaaatc agctgatttt ctagttcatt tgtggtcatt ttttgtactc
     3781 atataccttt aagatataaa aggaggttga catgtatcga attctaaatc caatgaatca
     3841 caatgtctcg cttgtcagaa atgataaggg agaagaggtg attgtaattg gtaaggggat
     3901 tgcattcgga aagaagaagg gggatttgat tgctgaaaat catgttgaga aaatctttcg
     3961 gatgaagacc gaagagtcca gagaaaactt tatggctctt ctcaaagatg ttccgcttga
     4021 ttttatcaca gtgacctatg aaatcattga taagctatca aagaaatatc attatccgat
     4081 tcaagagtat ctctatgtaa ccttgacaga tcatatttac tgttcttatc aagctctaat
     4141 tcaaggaagg tacaaggata gtaatctgcc agatatttct gctaagtatc ctgtcgcttt
     4201 tcaaatcgca aatgaagctt ttgaaattta ccgtcagaag ctagcagatc attttcctga
     4261 ggacgaaatt attcggattg cttatcattt cattaatgct gaaggtgaaa atgaagtgga
     4321 acttgtggag tcgattgata agaggaaaga aattctcagg aatgttgaag aagttttaac
     4381 ggactatgca attcaacgaa ctaaaaagaa taaccatttc tatgatcgct ttatgatcca
     4441 tttgaattat ttcttggatt atttagacag atctagagat gataaccaat cacttctgga
     4501 tatggaagat catattaaac aatcctatcc aaaagccttc gagattggtt ccaagatcta
     4561 tgatgtgatt acgcaacata cgggtcttga tttgtataaa agtgaacgag tttatctagt
     4621 tctacatatc caacgtttat tgtcataaaa atttatttaa aactatataa ggagaattct
     4681 atcatgaata gagaagaagt aacattgtta ggttttgaaa tcgtagccta tgctggcgat
     4741 gctcgttcaa aactattgga agccttgaag gctgctgaag ctggtgattt tgaaaaagcg
     4801 gacgctctgg tagaggaagc tggtagctgt attgcagagg ctcaccacgc gcaaacaagt
     4861 ctattgacta aggaagcttc tggtgaggac ttagcgtata gtgtgaccat gatgcatggt
     4921 caagatcact tgatgacaac tatcttgtta aaagacctaa tgcaccattt aattgaactt
     4981 tacaagagag gagttaaata aaatggataa gttaataatt tttattgaga aaggaaagcc
     5041 tttctttgag aaattatcga gaaatatata cttaagagcg ataaaagatg gttttatttc
     5101 cagtatgcca gcagtattat tctcaagtat ttttatacta atagctgctg tgcccaatat
     5161 ttttgggttt aaatggtctg atgaacagtt agcttttatt ttgaaacctt acaactactc
     5221 aatggggatt ttagctctct tagtagctgg gacaactgca aaatcgttaa cagattcagt
     5281 taatacacgt agtatggaga aaaccaacca aatcaactac atgtcaactt ttttagcagc
     5341 tgttgttgga ttgttaatac tggcagctga tccaattgaa ggtggatttg ctaatggtct
     5401 tttaggtact agaggattac ttactgcatt tttggcagct tttattacag taaatatcta
     5461 taaagtatgt attaaaaata atgtaaccat tagacttcct gaagaggttc caccaaatat
     5521 tgcacaagtt tttaaagatg ttattccgtt tgccttatct gttctttcaa tatatggatt
     5581 ggatttaatt gttagaaata tttttggtac aaatgtagca gaatctgttg gtaaaatatt
     5641 agcccctcta ttttcagcta ctgatggtta tatcggttta gctattgtat ttggtgctta
     5701 tgctttcttt tggtttgttg gaattcatgg gccatctgtt gtagaacctt taattgtagc
     5761 tatcagttat gcaaatatag aagctaatgt tcagcttgtg caagctggta tgcacgcaga
     5821 taaaatttta aatccagtta ctcaaacttt tgttgtaaca atgggtggta ctggtgcaac
     5881 actagtagtt ccatttatgt ttatgtggtt atgtaaatca aaaagaaata gaattgtcgg
     5941 acgtgcgtct gtagttccta ctttctttgg cgtaaatgaa ccaatcctat ttggtgctcc
     6001 aattgtttta aatcctatct tctttattcc gtttgttact gctcctatta tcaatgtttg
     6061 gattatgaaa ttttttgtag atgttctaca aatgaatagt ttcagtatta ttttaccttg
     6121 gacaacacct gctccaattg gtattgttat gggaacggcg ctggctccat tgtcattcgt
     6181 cttggctata actttaatca ttatcgacac tttaatctat tatccatttg ttaaagttta
     6241 tgaccatcaa attttagaag aagaacgttc aggtaagtct aatgatgaat tgaaagaaaa
     6301 agttgctgca aacttcaaca ctgcaaaagc ggatgctatt cttgaaaaag cgggtgtcga
     6361 tgcagcacaa aataccatca ctgaagaaac aaatgtcctc gttctctgtg caggtggagg
     6421 aacaagtggt ctccttgcaa atgctttgaa taaggcagca gcagaataca atgtccctgt
     6481 gaaagcagca gcaggcggct atggtgctca ccgtgaaatg ttaccagagt ttgatcttgt
     6541 tatccttgcc cctcaagttg cttcaaactt tgaagatatg aaagcagaaa cagataagct
     6601 cggtattaaa ctagcgaaaa cagaaggcgc tcaatacatc aaattaactc gtgatggaaa
     6661 aggtgctctt gcattcgtac aagcgcaatt cgattaaggc tagagactct gaaatagtct
     6721 cctatcgtta cggaaatcgc tatggcgaat ttcctattat taattcgtcg gtaaaaagat
     6781 atcgttttta cctcctcatg tcacaattcg gtgacttggt acaagaagtg agatggagaa
     6841 ggatggctca ctgactcctc tcctctcact tttactttat ttaaatcaag aaataggtga
     6901 aaaaaatgac aaaaacactt ccaaaagact ttatttttgg tggcgcaaca gctgcctatc
     6961 aagcagaagg tgctacacat actgatggta aaggaccagt agcgtgggat aaatatcttg
     7021 aagataacta ctggtacact gcagaaccag ccagtgattt ttacaatcga tatccagttg
     7081 acctcaagct agcagaagag tatggtgtca atggtattcg aatttctatt gcttggtcac
     7141 gtattttccc gactggttac ggccaagtaa atgctaaagg tgttgagttt tatcataatt
     7201 tatttgcaga gtgtcacaaa cgtcatgttg agccctttgt aactcttcat cactttgaca
     7261 cgccagaagc tctccactca aatggagact tcttaaaccg tgaaaatatc gaacattttg
     7321 tagactacgc tgccttctgt tttgaagaat ttccagaagt aaactattgg acaaccttta
     7381 atgaaattgg gccaattggt gatggtcaat acttggttgg gaaattccct ccaggtattc
     7441 agtacgacct tgccaaagtc ttccaatcgc accacaatat gatggtgtct catgcgcgtg
     7501 cagttaagct atataaagat aaaggctata aaggcgaaat tggtgttgtt cacgctctgc
     7561 caactaagta tcctttagat cctaaaaatc cgtcagatgt tcgtgcagct gagttggaag
     7621 atattattca caataaattt atcttggatg caacttatct aggtcgctat tcagctgaaa
     7681 cgatggaagg tgtcaaccat atcttatcag tcaatggtgg tagcttggat cttcgtgaag
     7741 aagattttac agcattagaa gcagcaaaag acttgaatga tttccttgga atcaactact
     7801 atatgagtga ctggatggaa gcctttgatg gagaaactga aattatccat aatggtaagg
     7861 gtgagaaagg aagttctaaa taccaaatca aaggtgttgg tcgtcgtgta gctcctgatt
     7921 atgtaccacg tacggattgg gattggatta tctaccctca aggtttatat gaccaaatta
     7981 tgcgtgtgaa gaaagattat cctaactaca agaagattta catcactgaa aatggtctcg
     8041 gctataaaga tgagttcgtc gataacactg tttatgatga tggacgtatt gattatgtga
     8101 aacaacactt ggaggtcttg tctgatgcga ttgcagatgg agcgaatgta aaaggttact
     8161 tcatttggtc attgatggac gtcttttcat ggtcaaatgg ttatgaaaaa cgttacggtc
     8221 tcttctatgt agactttgaa actcaagaac gttatccgaa gaaatcagct cactggtaca
     8281 agaaagtagc ggaaactcag attatagact agtagaatta gtcattagat atagaatttt
     8341 agtgagtcaa aaagatgttc aaagatttta tccaatctat ttatgaaaaa gtttatatta
     8401 taaatttcga aaaatgctct caaataccgt gtttgacgag tgaagaattg aaaagtctat
     8461 ttttaaattt tatcaatcct gaagaatggg atactatctc ctttgattca gattttatgc
     8521 catttcaaca atcgtaacca atttctcaaa aaagttaaat cttatattta gtactctgca
     8581 aaactcttat ctaatcacgt tgcttatact caatgaaaat caaagagcaa ctttaaacta
     8641 ggaagcgagt cgcagatttc tcaatgcata gctttgagga attgggcaaa aagtctttga
     8701 tatagaaaaa gcatagtatc aggtgtttca acacctgata ctatgctttt tattgtggga
     8761 agatttactt tttttcttct gaaattgagt tgttacccag gctctttcag tttattaagg
     8821 cttgatgact ttaatgtgtt tagatagctt aaaaaggatt gaatcactta gtttagaatc
     8881 tgaaacaata gtatcaagat ttgatacatt ataaaaagta taaaaatcaa acttattgaa
     8941 cttactatga tctgcgagta aatatttttt attagaatta tttaaagcga tgcgttgagc
     9001 ctctccctct tcctcgctaa aagtagctag agctccgttt tgaataccat tacagctaac
     9061 gaaagcttta gaaaattgga gattagagag attttgtagg gtcaatgtgc caacaaaagc
     9121 acctgtaata tcgcgataat ttccacctat caaaatcaaa tctgttaatt ttcgttcgct
     9181 taaaatcaga aaaacaggta gactgttggt tacgacgcgg atattgtcaa taggcaactc
     9241 acgcgcaaaa aactctaatg ttgttcctgg tccaatgaaa atagtttctc tttcttctac
     9301 tagactgcct gcaaaatggg ctatttcttg tttttctgcc gtttggaggg cttgtttttc
     9361 aatatttgat cgctcattag tcaaaaggga gttggttcga agtttttcag ctccaccatg
     9421 cacacgaatc agcaaatctt tatcagctaa ttcctgtaaa tagcgccttg cagtcatatc
     9481 tgaaacggct atttcgtcca taatctgttt aactgttatg gttcctttac tatttactat
     9541 ctctaaaatt ttggctaatt tttcttgttt gagcatatta tcacctcgtt tcctactact
     9601 atcttaccat aaacaaactc atcattcaaa tacaaaaaca acaaaatgaa acaaaaacaa
     9661 aaatatcgaa gtttgttttc aaaactttcg atatttttgt tgggttataa ctttgatgtt
     9721 tctagtttac tttttgatga ttgagagtga tggagaatta gtctaaaccg tagttatagt
     9781 catcgtcttg catggcttca acttcgccaa gaaggtaacc atttccgact tgagagaaga
     9841 agtcatggtt ggaagttcct gttgaaatac cgttcataac gattgggttg acatcttcag
     9901 ctgaatctgg gaaaagtgga tcttgtccca tgttcatgag agctttattg gcattgtagc
     9961 gaaggaaggt tttaacctct tcagtccaac caacaccgtc ataaagactc tctgtgtagc
    10021 cttcttcatt ttcataaaga gtatagagta ggtcgtacat ccattctttg agtttttctt
    10081 gctcttcttc aggcaattca ttgaaaccaa gttggaattt gtaaccaatg taggttccgt
    10141 gaacagactc gtcacgaata atcaatttaa tgatttctgc aacgttggct agtttgttgt
    10201 taccgagata gtagagggga gtgaagaaac cagagtagaa gaggaaggtt tcgaggaaga
    10261 cgctggcaac tttcttttca agtgggctgc cgtttaggta gatttcgttg acaatctcag
    10321 ccttcttttg taggtaagga ttggtattgg tccattcgaa aatttcttca atctcagcct
    10381 tagtattcaa ggtagaaaag attgatgagt aagatttagc gtggacagat tccataaatt
    10441 ggatgttatt gaaaacagct tcctcatgtg gtgtacggat gtctgcgcga agggcttgaa
    10501 ccccagtttc agattgcata gtgtcaagaa gggttaaacc accaaaaact tttccgacca
    10561 agtctttctc tttgttagat agctttctcc agtcatccaa gtcgtttgat aagggaatac
    10621 gtgtatcgag ccaaaattgc tccgtcagtt tttcccaagt tgatttgtcg atgacatctt
    10681 cgatggcatt ccagttaatg gctttgtagt aagtttccat ttaaaatctc tttctgtgtt
    10741 tagtattgcg aactcacaat tatttctact ttaccataat tctataggag tatcgcacaa
    10801 aaagtcggaa gcccgacttt taaaatgtta cataaattat gttatgacat agtagatttg
    10861 attttatcag tgctgcttag ggaaaaataa tgtttctatg ctagaaacta aatcacacag
    10921 ctttcacatt ggttggcgcc gacttctcca ccgtcatctg taaaggtacg gacgtagtag
    10981 atagacttga ttcccttgtt aaaggcatag ttacgaagga tggacaagtc acgtgtcgtt
    11041 tgtttatttt ccctcttcca ttcgtaaagg ccttttggaa tgtcactacg catgaagagg
    11101 gtgagtgaaa gtccttgatc cacgtgttca gtcgcagcag cgtaaacatc gatgacttta
    11161 cgcatatcca tatcgtaggc agaagtgtag taaggaatgg tttctgtaga caagccagca
    11221 gcagggtagt agattttacc aattttcttc tcttggcgtt cttcgatacg ttgcgtaatc
    11281 gggtggatag aagcagaaac gtcgttgata tagctgatag aaccatttgg cgctacagca
    11341 aggcgatttt ggtggtaaag accatcttct tgaaccttgt cgcgaagttc agcccaatca
    11401 gcaacaccag ggataaagac atttttgaag agttctttaa cacggtctga tgttggaaca
    11461 aattcaccag ttacatactt gtcaaagtaa cttccgttag catagtctga tttttcaaag
    11521 ttgtggaagg taataccacg ttcacgcgca atattgtttg actctaccaa ggtccagtag
    11581 ttcataagca taaagtagat gcttgtaaat tcaacagact caggtgaacc atattcaatg
    11641 agttgttggg caaggtagct gtgcagtccc atggcaccga gaccaaaggt gtgggcttgg
    11701 ctatttccat ggtcaatcgt tggtacagct acgatatgtg aactatctgt aacgaaagta
    11761 agggcacgaa ccatagcacg gatagaacga ccaaaatcag gtgaagtcat catgttaacc
    11821 acgttggttg aacccaggtt acatgaaaca tctgttccca tttgaaggaa ttcttgagca
    11881 tcgttgatca agcttggttc ttgaacttga agaatctcag aacacaagtt actcatgata
    11941 atctttccat caacaggatt tgcacggtta gccgtatcga tgttgactac ataaggatag
    12001 ccagactctt gttgcaattt agagatttca gtttccaaat cccgcgcctt gatttttgtc
    12061 ttgcgaatat ttggatttgc gaccaattca tcgtattttt cagtaatgtc gatgtaattg
    12121 aatggcacac cgtattcttt ttctacagag taagggctga agaggtacat ttcttcattt
    12181 ttacgagcca attcgtagaa tttatcaggt actacaacac caagtgatag agtcttgaca
    12241 cgtacttttt catcagcgtt ttctttctta gttgaaagga aagcgatgat atctgggtga
    12301 aagacgttga ggtagacaac accggcacct tgacgttgcc ccaattggtt ggagtaagag
    12361 aagctgtctt caaaaagctt cataacagga acgacacctg aagcagctcc ttcatagcct
    12421 ttgataggtg caccagcttc acgaaggttg ctgagggtaa ttcccacacc accaccaata
    12481 cgtgaaagtt gaagagctga gttgatagaa cgtccgatag agttcatatc atccgtcact
    12541 tggattagga aacaagatac caactctcca cggcgagcac gtccagcatt caagaaggaa
    12601 ggagtagcag gttggtagcg ttggtggatg atttcattgg caatatcgat tgcaacagct
    12661 tcattcccat cagcgaaata aagggcgttg aagaagacac ggtcttccat attttcaaga
    12721 tagtattcac cgtcattagt ctttaaggca tattgattgt aaaatttata agctgccatg
    12781 aatgacttga attggaagtt ttggtctttg ataaattgag ctaattcttc caagaactct
    12841 ggacggtatt tcttgataaa ggctgtttcg atgtagttgt gttcaatgag gtaattgatt
    12901 ttgtctttga ttgaatcaaa aaccatagtg tttggaacta cattttcttt aaagaaagca
    12961 tccaaggctt ccttgtcttt atgaagcatg atttgtccat taacaggacg gttaatttcg
    13021 ttattaagac ggaagtaagt cacgtcttca agatgtttta atcccataaa atttccctta
    13081 tctaattaca aaagaaaggc ttctaagtta gccctaaaag cagtttcttc tggatgatgt
    13141 actaagatta tgctaattgt ttcagttttc ctggttggaa acctgaaaag acttcagttg
    13201 gtgtttggat aacaggagct gcgctaaaac cgagctcttt aacttgatcg acgtactcag
    13261 gttgctcatc aagattgatt tcacgataag agacattatt actgtccaag aaacgcttgg
    13321 tcattttaca ttggacacaa ttgtttttag aataaacggt taccattgtg taactcctct
    13381 tcaaaattta atactatctt agtatatcag aaaataaaat tttgtcaatg atttgaacta
    13441 aatatagtgg tgttcttttg ttgtttttat atataaacac aatatatagt gtttgtattg
    13501 tgaaatagca atgattatcc tataaattgt ttttaaagaa actatatcct gtgttttgtt
    13561 atctaggata gaagattttc agcaagttat ctgaaaggaa attgaaggaa aatccagaaa
    13621 atgcttgaaa aaaatcctag aagatggtat aatactaaat tgtaagggtt atcacatata
    13681 actcaaaaaa agaaagaaca aaaggagagt caaactatgg cttctaaaga tttccacgta
    13741 gtggcagaaa caggtattca cgcacgtcca gcaacattgt tggtacaaac tgctagcaaa
    13801 tttgcttcag atatcactct tgagtacaaa ggtaaatcag ttaaccttaa atcaattatg
    13861 ggtgttatga gtcttggtgt tggccaaggt gctgacgtaa ctatctcagc tgaaggtgca
    13921 gatgcagatg acgctatcgc tgcaatctca gaaacaatgg aaaaagaagg attggcataa
    13981 gggaaatgac agaaatgctt aaaggaatcg cagcatctga cggtgttgca gttgcaaaag
    14041 catatctact cgttcagccg gatttgtcat ttgagactat tacagtcgaa gatacaaacg
    14101 cagaagaagc tcgccttgat gccgctctac aggcatcaca agacgagctt tctgttattc
    14161 gcgagaaagc agtaggtacg ctcggtgaag aagcagctca agtttttgat gctcacttaa
    14221 tggttcttgc tgacccagaa atgatcagcc aaatcaagga aactatccgt gcgaagaaag
    14281 tgaatgcaga agcaggtctg aaagaagtta cagatatgtt tatcactatc tttgaaggca
    14341 tggaagacaa cccatacatg caagaacgcg cagcggatat ccgcgacgtg acaaaacgtg
    14401 tattggcaaa ccttcttggt aaaaaattgc caaacccagc ttctattaat gaagaagtga
    14461 ttgtgattgc gcatgacttg acaccatctg atacagctca attggacaaa aactttgtaa
    14521 aagcttttgt aaccaacatt ggtggacgta caagccactc agctatcatg gcacgtacac
    14581 ttgaaattgc tgctgtatta ggtacaaata acatcactga aatcgttaaa gacggtgaca
    14641 tccttgctgt taacgggatc actggagaag tgattatcaa cccaacagat gaacaagcgg
    14701 cagaatttaa agcagctggt gaagcctatg cgaaacaaaa agctgaatgg gcacttttga
    14761 aagatgctca aacagtgact gctgacggta aacacttcga gttggctgcc aatattggta
    14821 ctccaaaaga cgttgaaggt gttaacaaca acggtgcaga agctgttgga ctttaccgta
    14881 cagagttctt gtacatggat tctcaagact tcccaactga agatgagcag tatgaagcat
    14941 acaaggctgt tcttgaagga atgaacggta aacctgttgt cgttcgtaca atggatatcg
    15001 gtggagataa ggaacttcct tacttcgata tgcctcacga aatgaaccca ttccttggat
    15061 tccgtgctct tcgtatctct atctctgaga ctggagatgc tatgttccgc acacaaatcc
    15121 gtgctcttct tcgtgcgtct gttcacggtc aattgcgtat catgttccca atggttgcgc
    15181 tcttgaaaga attccgtgca gcgaaagcag tctttgatga agaaaaagca aaccttcttg
    15241 ctgaaggtgt tgcagttgcg gataacatcc aagttggtat catgatcgag attcctgcag
    15301 cggctatgct tgcagaccaa tttgctaaag aagttgactt cttctcaatt ggtacaaacg
    15361 acttgatcca atatacaatg gcagcagacc gtatgaacga acaagtttca tacctttacc
    15421 aaccatacaa cccatcaatc ctacgcttga ttaacaatgt gatcaaagca gctcacgctg
    15481 aaggtaaatg ggctggtatg tgtggtgaga tggctggtga ccaacaagct gttccacttc
    15541 ttgtcggaat gggcttggat gagttctcta tgtcagcaac atctgtactt cgtacacgca
    15601 gcttgatgaa gaaactcgac acagctaaga tggaagagta cgcaaaccgt gcccttacag
    15661 aatgctcaac aatggaagaa gttcttgaac ttcaaaaaga atacgttaat tttgattaat
    15721 cgaaaagtcc ctgcaactca gttacaggga ctttttttga tattttaaaa agaattttca
    15781 agaaaatctt tcttataaaa agtccaacct tgaaaaagta gtggtcagaa caaaaaatac
    15841 ttaaatggtt cataaaattc ttgacaagtt ggagatttag gagtaaacta ttaaccagtt
    15901 aagtaataga gaggagtttc tgcaatttag aaatgaattg caactagaaa tatcaaatag
    15961 aaagagagtt tcgatgaaaa ttaataagaa ataccttgtt ggttctgcgg cagctttgat
    16021 tttaagtgtt tgttcttacg agttgggact gtatcaagct agaacggtta aggaaaataa
    16081 tcgtgtttcc tatatagatg gaaaacaagc gacgcaaaaa acggagaatt tgactcctga
    16141 tgaggttagc aagcgtgaag gaatcaatgc tgagcaaatc gtcatcaaga taacagacca
    16201 aggctatgtc acttcacatg gcgaccacta tcattattac aatggtaagg ttccttatga
    16261 tgcgattttc agtgaagaat tactcatgaa agatccaaac tataagctaa aagatgagga
    16321 tattgttaat gaggtcaagg gtggatatgt tatcaaggta gatggaaaat actatgttta
    16381 ccttaaggat gctgcccacg cggataacgt ccgtacaaaa gaggaaatca atcgacaaaa
    16441 acaagaacat agtcaacatc gtgaaggtgg gactccaaga aacgatggtg ctgttgcctt
    16501 ggcacgttcg caaggacgct atactacaga tgatggttat atctttaatg cttctgatat
    16561 catagaggat actggtgatg cttatatcgt tcctcatgga gatcattacc attacattcc
    16621 taagaatgag ttatcagcta gcgagtt
//
LOCUS       DAVBDR010000046        16132 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.046, whole genome shotgun sequence.
ACCESSION   DAVBDR010000046 DAVBDR010000000
VERSION     DAVBDR010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16132)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16132)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16132
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.046"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            145..6831
                     /locus_tag="VQ540_001558"
     CDS             145..6831
                     /locus_tag="VQ540_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ig-like domain-containing protein"
                     /protein_id="HET2545339.1"
                     /translation="MGKGHWNRKRVYSIRKFAVGACSVMIGTCAVLLGGNIAGESVVY
                     ADETLITHTVEKPKEEKMIVEEKADKALETKNVVERTEQSEPSSTEAIASEKKEDEAV
                     TPKEEKVSAKPEEKAPRIESQTSNQEKPLKEDAKAVTNEEVNQMIEDRKVDFNQNWYF
                     KLNANSKEAIKPDVDVSTWKKLDLPYDWSIFNDFDHESPAQNEGGQLNGGEAWYRKTF
                     KLDEKDLKKNVRLTFDGVYMDSQVYVNGQLVGHYPNGYNQFSYDITKYLHKDGRENVI
                     AVHAVNKQPSSRWYSGSGIYRDVTLQVTDKVHVEKNGTTILTPKLEEQQHGKVETHVT
                     SKIVNTDDKDHELVAEYQIVERGGHAVTGLVRTASRTLKAHESTSLDAILEVERPKLW
                     TVLNDKPALYELITRVYRDGQLVDAKKDLFGYRYYHWTPNEGFSLNGERIKFHGVSLH
                     HDHGALGAEENYKAEYRRLKQMKEMGVNSIRTTHNPASEQTLQIAAELGLLVQEEAFD
                     TWYGGKKPYDYGRFFEKDATHPEARKGEKWSDFDLRTMVERGKNNPAIFMWSIGNEIG
                     EANGDAHSLATVKRLVKVIKDVDKTRYVTMGADKFRFGNGSGGHEKIADELDAVGFNY
                     SEDNYKALRAKHPKWLIYGSETSSATRTRGSYYRPERELKHSNGPERNYEQSDYGNDR
                     VGWGKTATASWTFDRDNAGYAGQFIWTGTDYIGEPTPWHNQNQTPVKSSYFGIVDTAG
                     IPKHDFYLYQSQWVSVKKKPMVHLLPHWNWENKELASKVADSEGKIPVRAYSNASSVE
                     LFLNGKSLGFKTFNKKQTSDGRTYQEGANANELYLEWKVAYQPGTLEAIARDESGKEI
                     ARDKITTAGKPAAVRLIKEDHAIAADGKDLTYIYYEIVDSQGNVVPTANNLVRFQLHG
                     QGQLVGVDNGEQASRERYKAQADGSWIRKAFNGKGVAIVKSTEQAGKFTLTAHSDLLK
                     SNQVTVFTGKKEGQEKTVLGTEVARVRTLIGKEPKMPKTVGFVYSDGSREKLPVTWSQ
                     VDVSQAGVVTVKGTANGREVEAHVEVLAIAKELPTVKRIAPNTDLNSVDKSVSYVLTD
                     GSVQEYEVDSWEITEVDKAKLSVAGSRIQMTGQLAGETIHATLVVEEGNAAAPVVPTV
                     TVGGEAVTGLTSRQPMQYRTLSYGAQLPEVTASAENADVTVLQASAANGMRASIFIQP
                     KDGGPLQTYAIQFLEEAPKIAHLSLQVEKADSLKEDQTVKLSVRAHYQDGTQAVLPAD
                     KVTFSTSGEGEVAIRKGMLELHKPGAVTLKAEYEGAKGQVELTIQANTEKKIAQSIRP
                     VNVVTDLHQKPTLPTTVTVEYDKGFPKAHKVTWQAIPKEKLDSYQTFEVLGKVEGIDL
                     EARAKVSVEGIVSVEEVSVTTPIAEAPQLPESVRTYDSNGHVSSAKVAWDAIRIEQYA
                     KEGVFTVNGRLEDTQLTTKLHVRVSAQTEQGANISDQWTGSELPLAFASDSNPSDPVS
                     NVNDKLISYNNQPANRWTNWNRTNPEASVGVLFGDSGILSKRSVDNLSVGFHEDHGVG
                     APKSYVIEYYVGKTVPTAPKNPSFVGNEDHVFNDSANWKPVTNLKAPAQLKAGEMNHF
                     SFDKVETYAVRIRMVKADNKRGTSITEVQIFAKQVAAAKQGQIRIQVDGKDLANFNPD
                     LTDYYLESVDGKVPAVTASVSNNGLATVVPSVREGEPVRVIAKAENGDILGEYRLHFT
                     KDKNLLSHKPVAAVKQARLLQVGQALELPTKVPVYFTGKDGYETKDLTVEWEEVPAEN
                     LTKAGQFTVRGHVLGSDLVAEVTVRVTDKLGEALSDNPNYDENSNQAFASATNDIDKN
                     SHDRVDYLNDGDHSENRRWTNWSPTPSSNPEVSAGVIFRENGKIVERTVAQAKLRFFA
                     DSGTDAPTKLVLERYVGPEFEVPTYYSNYQAYDADHPFNNPENWEAVPYRADKDIAAG
                     DEINVTFKAVKAKAMRWRMERKADKSGVAMIEMTFLAPSELPQESTQSKILVDGKELA
                     DFAENRQDYQITYKGQRPKVSVEENNQVASTVVDSGEDSLPVLVRLVSESGKQVKEYR
                     IQLTKEKPVSAVQEDLPKLEFVEKDLAYKTVEKKDSTLYLGETRVEQEGKTGKERIFT
                     AINPDGSKEEKLREVVEAPTDRIVLVGTKPVAQEAKKPQVSEKADTKPIDSSEASQTN
                     KAQLPNTGSAASQAAVAAGLALLGLSAGLVVTKGKKED"
     gene            complement(7079..7935)
                     /locus_tag="VQ540_001559"
                     /pseudo
     CDS             complement(7079..7935)
                     /locus_tag="VQ540_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270419.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(8146..8505)
                     /locus_tag="VQ540_001560"
     CDS             complement(8146..8505)
                     /locus_tag="VQ540_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HET2545340.1"
                     /translation="MGMILMKLASILLLILTLVVCIILTKLFRLKKLGRNFADLAFPV
                     LVFEYYLITAKTFTHNFLPRLGLALSILAIILVFFFLLKKRSFYYPKFIKFFWRAGFL
                     LTLIMYIEMIVELFLMK"
     gene            8597..9553
                     /locus_tag="VQ540_001561"
                     /pseudo
     CDS             8597..9553
                     /locus_tag="VQ540_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002881980.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein.; internal stop;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
     gene            9537..10094
                     /locus_tag="VQ540_001562"
     CDS             9537..10094
                     /locus_tag="VQ540_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HET2545341.1"
                     /translation="MKRPLEMAHDFLAEVVTKEDVVVDATMGNGHDTLFLAKLAKQVY
                     AFDIQKQALEKTQERLHQADLTNAQLILQGHETLDQFVIKAKAGIFNLGYLPSADKSV
                     ITRPQTTIEALEKLCGLLVKGGRIAIMIYYGHEGGDLERDAVLDFVIQLNQQEYTAAI
                     YRTLNQVNNPPFLVMIEKLERYRHG"
     gene            10087..10341
                     /locus_tag="VQ540_001563"
     CDS             10087..10341
                     /locus_tag="VQ540_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2545342.1"
                     /translation="MDKQYLHEKLDAMRQNFVESTHHERSVGVLDQAHMSKKMLKIKK
                     KLVALEMERCQRKIEHKDCSKIDQKIKEQKEIFESCCKKD"
     gene            10353..12407
                     /locus_tag="VQ540_001564"
     CDS             10353..12407
                     /locus_tag="VQ540_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000421632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HET2545343.1"
                     /translation="MELLIYLILFLLVLIVSSTTNKLLPFLPLPLVQILLGIVIGLFL
                     PNTDFHLNTELFLALVIGPLLFREAEEADVTAILKHWRIIVYLIFPVIFISTLSLGGL
                     AHLLWFSLPLAACLAVGAALGPTDLVAFASLSERFSFPKRVSNILKGEGLLNDASGLV
                     AFQVALTAWTTGAFSLGQASSSLIFSILGGFLIGFLTAMTNRFLHTFLLSVRATDIAS
                     ELLLELSLPLVTFFLAEEVHVSGIIAVVVAGILKASRFKKITLLEAQVDTVTETVWHT
                     VTFMLNGSVFVILGMELEMIAEPILTNPIYNPLLLLLSLIALTFVLFVIRFIMIYGYY
                     AYRTRRLKKKLNKYMKDMFLLTFSGVKGTVSIATILLIPSNLEQEYPLLLFLVAGVTL
                     VSFLTGLLVLPHLSDEEEESKDYLMHIAILNEVTLELEKELEDTRNKLPLYAAIDNYH
                     GRIENLILSQENQDDQEDWAALKLLILSIESDGLEQAYEEGNISNRAYRVYQRYLKNI
                     EQGINRKLASRLTYYFLVSLRILRFLLHEVFTLGKTFRSWKDKEQSRLRALDYDQIAE
                     LYLANTEMIIESLENLKGVYRRSLISFMQESRLRETAIISSGAFVERVINRVKPNNID
                     EMLRGYYLERKLIFEYEEKRLITTKYAKKLRQNVNNLENYSLKEAANTLPYDMVELVR
                     RN"
     gene            12586..13446
                     /locus_tag="VQ540_001565"
     CDS             12586..13446
                     /locus_tag="VQ540_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HET2545344.1"
                     /translation="MKKWWKELIDKPLLKAFLHYYQASDSELTSVAVAYYWLISIFPL
                     LLVVVNILPYFQIPVGEFLCFMKDVLPPSLYEGVEKIAREVLTQPSTGLLSFSVLSAL
                     WSFSKSMNFLQKAFNKAYGVEKSRGLISHQMLSLLVSFGLQLLFAFALFLILFGQMIL
                     ALLAHYWTKDGIIYQALQGLAGPLIYALLFAILVMLYYFLPNLSNRKISYTLPGSAFV
                     LLVILGLLTLFSSYLNYYVHHLVDVRILGSVLLVVMMFWFILIAKIVILGAVINASMQ
                     SLKDPVFKKD"
     gene            13657..14367
                     /gene="ccdA2"
                     /locus_tag="VQ540_001566"
     CDS             13657..14367
                     /gene="ccdA2"
                     /locus_tag="VQ540_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000509848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HET2545345.1"
                     /translation="MGHIFFFLSVFLAGILSFFSPCILPLLPVYTGVLLDDKDGAQAS
                     SGKFSISVTSLLRTLAFIAGISFIFILLGYGAGFLGDLLYASWFQYLTGAIIILLGLH
                     QMEILHFKGLYKEKRLQLQGQGQNGKGYSQAFLLGLTFSFAWTPCVGPVLGSVLALAA
                     SGGSGAWQGAGLMLVYTLGLALPFLLLALTSSYVLKHFRKLHPYLGILKKVGGFLIIV
                     MGLLVLFGNASILSQLFE"
     gene            14387..14953
                     /locus_tag="VQ540_001567"
     CDS             14387..14953
                     /locus_tag="VQ540_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redoxin family protein"
                     /protein_id="HET2545346.1"
                     /translation="MKKWQTCVLGAGSLLCLTACSGKSVTSEHQTKDEMKTEQTASKT
                     SAAKGKEVADFELMGVDGKTYRLSDYKGKKVYLKFWASWCSICLASLPDTDEIAKEAG
                     DDYVVLTVVSPGHKGEQSEADFKNWYKGLDYKNLPVLVDPSGKLLETYGVRSYPTQAF
                     IDKEGKLVKTHPGFMEKDAILQTLKELA"
     gene            14964..16076
                     /gene="msrB"
                     /locus_tag="VQ540_001568"
     CDS             14964..16076
                     /gene="msrB"
                     /locus_tag="VQ540_001568"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HET2545347.1"
                     /translation="MNDKLKIFLLLGVFFLAITGFYVLLIRNAGQTDASQIEKAAVSQ
                     GGKAVKKTEISKDADLHEIYLAGGCFWGVEEYFSRVPGVTDAVSGYANGRGETTKYEL
                     INQTGHAETVHVTYDAKQISLKEILLHYFRIINPTSKNKQGNDVGTQYRTGVYYTDDK
                     DLEVINQVFDEVAKKYDQPLAVEKENLKNFVVAEDYHQDYLKKNPNGYCHINVNQAAY
                     PVIDASKYPKPSDEELKKTLSPEEYAVTQENQTERAFSNRYWDKFESGIYVDIATGEP
                     LFSSKDKFESGCGWPSFTQPISPDVVTYKEDKSYNMTRMEVRSRVGDSHLGHVFTDGP
                     QDKGGLRYCINSLSIRFIPKDQMEEKGYAYLLDYVD"
BASE COUNT         4901 a         3052 c         3565 g         4614 t
ORIGIN      
        1 catatctacg gcaaggcgac actgacgaag tttgaattgg attttcgcag agtgtaaatt
       61 gttgaaacta ggttgtcata ccatgtatac cacttgggct ttggtagtag ctaactgcac
      121 taaatataat ataaggaggg ttttatgggg aaaggccatt ggaatcggaa aagagtttat
      181 agcattcgta agtttgctgt gggagcttgc tcagtaatga ttgggacttg tgcagttcta
      241 ttaggaggaa atatagctgg agaatctgta gtttatgcgg atgaaacact tattactcat
      301 actgttgaga aacctaaaga ggaaaaaatg atagtagaag aaaaggctga taaagctttg
      361 gaaactaaaa atgtagttga aaggacagaa caaagtgaac ctagttcaac tgaggctatt
      421 gcatctgaga agaaagaaga tgaagccgta actccaaaag aggaaaaagt gtctgctaaa
      481 ccggaagaaa aagctccaag gatagaatca caaacttcaa atcaagaaaa accgctcaag
      541 gaagatgcta aagctgtaac aaatgaagaa gtgaatcaaa tgattgaaga caggaaagtg
      601 gattttaatc aaaattggta ttttaaactc aatgcaaatt ctaaggaagc cattaaacct
      661 gatgtagacg tatctacgtg gaaaaaatta gatttaccgt atgactggag tatctttaac
      721 gatttcgatc atgaatctcc tgcacaaaat gaaggtggac agctcaacgg tggggaagct
      781 tggtatcgca agactttcaa actagatgaa aaagacctca agaaaaatgt tcgccttact
      841 tttgatggcg tctacatgga ttctcaagtt tatgtcaatg gtcagttagt ggggcattat
      901 ccaaatggtt ataaccagtt ctcatatgat atcaccaaat accttcacaa agatggtcgt
      961 gagaatgtga ttgctgtcca tgcagtcaac aaacagccaa gtagccgttg gtattcagga
     1021 agtggtatct atcgtgatgt gactttacaa gtgacagata aggtgcatgt tgagaaaaat
     1081 gggacaacta ttttaacacc aaaacttgaa gaacaacaac atggcaaggt tgaaactcat
     1141 gtgaccagca aaatcgtcaa tacggacgac aaagaccatg aacttgtagc cgaatatcaa
     1201 atcgttgaac gaggtggtca tgctgtaaca ggcttagttc gtacagcgag tcgtacctta
     1261 aaagcacatg aatcaacaag cctagatgcg attttagaag ttgaaagacc aaaactctgg
     1321 accgttttaa atgacaaacc tgccttgtac gaattgatta cgcgtgttta ccgtgacggt
     1381 caattggttg atgctaagaa ggatttgttt ggttaccgtt actatcactg gactccaaat
     1441 gaaggtttct ctttgaatgg tgaacgtatt aaattccatg gagtatcctt gcaccacgac
     1501 catggggcgc ttggagcaga agaaaactat aaagcagaat atcgccgtct caaacaaatg
     1561 aaggagatgg gagttaactc catccgtaca acccacaacc ctgctagtga gcaaaccttg
     1621 caaatcgcag cagaactagg tttactcgtt caggaagagg cctttgatac ttggtatggt
     1681 ggcaagaaac cttatgacta tggacgtttc tttgaaaaag atgccactca cccagaagct
     1741 cgaaaaggtg aaaaatggtc tgattttgac ctacgtacca tggtcgaaag aggcaaaaac
     1801 aaccctgcta tcttcatgtg gtcaattggt aatgaaatag gtgaagctaa tggtgatgcc
     1861 cactctttag caactgttaa acgtttggtc aaggttatca aggatgttga taagactcgc
     1921 tatgttacca tgggagcaga taaattccgt ttcggtaatg gtagcggagg gcatgagaaa
     1981 attgctgatg aactcgatgc tgttggattt aactattctg aagataatta caaagccctt
     2041 agagctaagc atccaaaatg gttgatttac ggttcagaaa catcttcagc tacccgtaca
     2101 cgtggaagtt actatcgccc tgaacgtgaa ttgaaacata gcaatggacc tgagcgtaat
     2161 tatgaacagt ctgactatgg aaatgatcgt gtgggttggg ggaaaacagc aaccgcttca
     2221 tggacttttg accgtgacaa cgctggctat gctggacagt ttatctggac aggtacggac
     2281 tatattggtg aacctacacc atggcacaac caaaatcaaa ctcctgttaa gagctcttac
     2341 tttggtatcg tagatacagc cggcattcca aaacatgact tctatctcta ccaaagccaa
     2401 tgggtttctg ttaagaagaa accgatggta caccttcttc ctcactggaa ctgggaaaac
     2461 aaagaattag catccaaagt agctgactca gaaggtaaga ttccagttcg tgcttattcg
     2521 aatgcttcta gtgtagaatt attcttgaat ggaaaatctc ttggttttaa gactttcaat
     2581 aaaaaacaaa ccagcgatgg gcggacttac caagaaggtg caaatgctaa tgaactttat
     2641 cttgaatgga aagttgccta tcaaccgggt accttggaag caattgctcg tgatgaatct
     2701 ggcaaggaaa ttgctcgaga taagattacg actgctggta agccagcggc agttcgtctt
     2761 attaaggaag accatgcgat tgcagcagat ggaaaagact tgacttacat ctactatgaa
     2821 attgttgaca gccaggggaa tgtggttcca actgctaata atctggttcg cttccaattg
     2881 catggccaag gtcaactggt cggtgtagat aacggagaac aagccagccg tgaacgctat
     2941 aaggcgcaag cagatggttc ttggattcgt aaagcattta atggtaaagg tgttgccatt
     3001 gtcaaatcaa ctgaacaagc agggaaattc accctgactg cccactctga tctcttgaaa
     3061 tcgaaccaag tcactgtctt tactggtaaa aaagaaggac aagagaagac tgttttgggg
     3121 acagaagtag caagagttcg tacattaatt ggtaaagaac caaaaatgcc gaaaacagta
     3181 ggttttgtat acagcgatgg tagtcgtgaa aaacttccag taacttggtc tcaagtcgat
     3241 gttagtcaag caggagttgt gactgttaaa ggtacagcaa atggacgtga ggtagaggct
     3301 catgtcgagg ttctagcaat tgcgaaagaa ttaccaacag ttaaacgtat tgctccaaat
     3361 actgacttga attctgtaga caaatctgtt tcttatgttt tgactgatgg aagtgtacaa
     3421 gagtacgaag tagatagctg ggagattacg gaagtagata aagccaaact ttcagtagct
     3481 ggatcacgta ttcaaatgac tggtcagtta gctggagaaa ctattcatgc aacccttgtg
     3541 gtagaagaag gaaatgctgc agcacctgta gtgccaactg ttactgttgg aggtgaggca
     3601 gtaacaggtc ttactagtcg acaaccaatg caatatcgta ctctatctta tggtgcccaa
     3661 ctgccagaag tcacagcaag tgctgaaaat gctgatgtga cagttcttca agcaagcgca
     3721 gcaaacggca tgcgtgcgag catctttatt cagcctaaag atggtggtcc tcttcaaacc
     3781 tatgcaattc aattcctaga agaagcacca aaaattgctc acttgagttt gcaagtggaa
     3841 aaagctgaca gtctcaaaga agaccaaact gtcaaattgt cggttcgagc tcactatcaa
     3901 gatggaacgc aagctgtatt accagctgac aaagtaacct tctctacaag tggtgaaggg
     3961 gaagtcgcaa ttcgtaaagg aatgcttgag ttgcataagc caggagcagt cactctcaaa
     4021 gcggaatatg agggagctaa aggccaagtt gaactcacta tccaagccaa tactgagaag
     4081 aagattgcgc aatctatccg tcctgtaaat gtagtcacag atttgcatca aaaacctact
     4141 cttccaacaa cagtaacggt tgagtatgac aaaggtttcc ctaaagctca caaagtcact
     4201 tggcaagcta ttccgaaaga aaaactagac tcctatcaaa catttgaagt actaggtaaa
     4261 gttgaaggaa ttgaccttga agcgcgtgca aaagtctctg tagaaggtat cgtttcagtt
     4321 gaagaagtca gtgtgacaac tccaatcgca gaagcaccac aattaccaga aagcgttcgg
     4381 acatatgatt caaatggtca cgtttcatca gctaaggttg catgggatgc gattcgtata
     4441 gagcaatacg ctaaggaagg tgtctttaca gttaatggtc gcttagaaga tactcaatta
     4501 acaactaaac ttcatgttcg cgtatctgct caaactgagc aaggtgcaaa catttctgac
     4561 caatggaccg gttcagaatt gccacttgcc tttgcttcag attcaaatcc aagcgaccca
     4621 gtttcaaatg ttaatgacaa gctcatttcc tacaataacc aaccagccaa tcgttggaca
     4681 aactggaatc gtactaatcc agaagcttca gtcggtgttc tgtttggaga ttcaggtatc
     4741 ttgagcaaac gctccgttga taatctaagt gtcggattcc acgaagacca tggagttggt
     4801 gcaccgaagt cttatgtgat tgagtattat gttggtaaga ctgtcccaac agctcctaaa
     4861 aaccctagtt ttgttggtaa tgaggaccat gtctttaatg attctgccaa ctggaaacca
     4921 gttactaatc taaaagcccc tgctcaactc aaggctggag aaatgaacca ctttagcttt
     4981 gataaagttg aaacctatgc tgttcgtatt cgcatggtta aagcagataa caagcgtgga
     5041 acgtctatca cagaggtaca aatctttgcg aaacaagttg cggcagccaa acaaggacaa
     5101 ataagaatcc aagttgacgg caaagactta gcaaacttca accctgattt gacagactac
     5161 taccttgagt ctgtagatgg aaaagttccg gcagtcacag caagtgttag caacaatggt
     5221 ctcgctaccg tcgttccaag cgttcgtgaa ggtgagccag ttcgtgtcat cgcgaaagct
     5281 gaaaatggcg acatcttagg agaataccgt ctgcacttca ctaaggataa gaacttactt
     5341 tctcataaac cagttgctgc ggttaaacaa gctcgcttgc tacaagtagg tcaagcactt
     5401 gaattgccga ctaaggttcc agtttacttc acaggtaaag acggctacga aacaaaagac
     5461 ctgacagttg aatgggaaga agttccagca gaaaatctga caaaagcagg tcaatttacc
     5521 gttcgaggcc atgtccttgg tagtgatctt gttgctgagg tcactgtacg agtgacagac
     5581 aaactaggcg aagctctttc agataaccct aactatgatg aaaacagtaa ccaggccttt
     5641 gcttcagcaa ccaatgatat tgacaaaaac tctcatgacc gcgttgacta tctcaatgac
     5701 ggagatcatt cagaaaatcg tcgttggaca aactggtctc caacaccatc ttctaatcca
     5761 gaagtatcag cgggtgtgat cttccgtgaa aatggtaaga ttgtagaacg gactgttgcc
     5821 caagccaaac ttcgtttctt tgcagatagt ggtacggatg caccaactaa actcgtttta
     5881 gaacgctatg tcggtccaga gtttgaagtg ccaacctact attcaaacta ccaagcctac
     5941 gacgcagacc atccattcaa caatccagaa aattgggaag ctgtgcctta tcgtgcggat
     6001 aaagacatcg cagctggtga tgaaatcaac gtaacattta aagctgtcaa agccaaagct
     6061 atgagatggc gtatggagcg taaagctgac aagagcggtg ttgcgatgat tgagatgacc
     6121 ttccttgcac cgagtgaatt gcctcaagaa agtacgcaat cgaagattct tgtagatgga
     6181 aaagaacttg ctgatttcgc tgaaaatcgt caagactatc aaattaccta taaaggtcaa
     6241 cggccaaaag tctcagttga agaaaacaat caagtagctt caactgtggt agatagtgga
     6301 gaagatagcc ttccagtact tgttcgcctc gtttcagaaa gtggaaaaca agtcaaggaa
     6361 taccgtatcc agttgactaa ggaaaaacca gtttctgctg tacaagaaga tcttccaaaa
     6421 ctcgaatttg ttgaaaaaga tttggcctac aagacagttg agaaaaaaga ttcaacactg
     6481 tatctaggtg aaactcgtgt agaacaagaa ggaaaaactg gtaaagaacg tatctttaca
     6541 gcgattaatc ctgatggaag taaggaagaa aaactccgtg aagtggtaga agctccgaca
     6601 gaccgcatag tcttggttgg aaccaaacca gtagctcaag aagctaaaaa accacaagtg
     6661 tcagaaaaag cagatacaaa accaattgat tcaagtgaag ctagtcaaac taataaagcc
     6721 cagttaccaa atacaggtag tgcggcaagc caagcagcag tagcagcagg tttagctctt
     6781 ctaggtttga gtgcaggatt agtagttact aaaggtaaaa aagaagacta gaaattttga
     6841 taccttcttt atcattaaag accaaagaaa aactcttgtc ctaaatagaa gataaagagt
     6901 ctggaacaaa atagttctca accacaaaaa agctagatat ttccaattgc ggaactctag
     6961 ctttttaatt ttgagtcgtt ctcttattgt atagtagatt gaaactagaa tagtacactt
     7021 ctacttctaa aacattgtta gaaatcaatt tgactgtcct tatcgatttg tcctgttctt
     7081 atttcatttc actatgtttt aggaggttat tggccataag taccaatccc atgtcaattc
     7141 tcacttgacg cttccctctc agattacatc tcttgtaacc caaacaagcc tttatctgcc
     7201 caaagacagg ttccacatca atcttgcgtt gagcgaaaat ctgtctacct tggggagata
     7261 aaagcgcctg acattcttta gctttcaagt tttgatagcg ttcgttcata tacagtccct
     7321 tttgagggac tgattcaggt tcatcagcgt agtaaacctt gatttcctgt tgaaagtctg
     7381 tctgtgtttt ctggtacttg atatggtgaa aacgatagca ccagccatca ggatgtgtgt
     7441 agctatcctc cttgtcatta tagtgccaat tcgctaagtt tttagctgac tgtttatacc
     7501 ctctcttttg ttccttatca aacatggcat atttaatcag aaggggagtg atttcttctt
     7561 gaaaatagac ctgtatctgt tcttgaagtt tggcggagaa tttctctgtc gttttcttcc
     7621 acacaaaact atacttgttg gcattggctt caatcttagt tccgtcaata aacaaacaat
     7681 ctaaggtcac taactcttcc atttttcaat ttttcgacca gagaaaatcc cttgtgaata
     7741 ggcaaataga agagtagata caagcatttt agggtgataa gacgggcgat caaaggcatg
     7801 atagaaggcg tggaagtgac aatcctccaa ggtattcacc actttttcaa tagtaaaaac
     7861 gagatgatct tgtggcaaga aggaactgat ttctagtggt aaagttgttt gatttgtgtt
     7921 atagtgaata tgcatgggat agcctttcta aatggtttat taagcaattc tattttacca
     7981 agactatcgc aaccatgcaa aaaagcaacg gcaaatccgt tgcctttttt ggagataaga
     8041 gactattgtc ccagactctt ttctttgtat aaaattgtat agtgttattg tctatactat
     8101 tttgtagaga aagcaaaaat ccctagaaaa tgcttaggga ttcgactatt tcattaagaa
     8161 caattcaaca atcatttcta tatacatgat aagggttaat aagaatcctg cacgccagaa
     8221 gaatttgata aatttaggat agtaaaagct gcgttttttc aaaaggaaga aaaagacgag
     8281 aataatggct aggatcgaga gggctagccc cagtctaggg aggaaattat gggtaaaggt
     8341 tttagctgta atcaagtaat actcaaatac caagactgga aaagccaaat ccgcaaagtt
     8401 tcgtcctagt ttttttaatc taaaaagttt ggttaggata atgcagacga ctaaggtcag
     8461 tatcaataat aaaatagatg ctaatttcat taaaatcata cccatattgt atcataaaaa
     8521 aaggctaatg gaaacgagaa acagaggaat ttataggaaa gtcaggcttt tgagattgtg
     8581 ggtgattttt gttataatga aagttataaa atcttataat accttgaatg attattatcg
     8641 aaaactcttt ggagaaaaga cttttaaagt ccctattgat gcgggatttg actgtcccaa
     8701 tcgtgatgga actgtggctc atggaggctg tactttttgt acggtttccg gttctggaga
     8761 tgccattgtg gcaccagatg cgcctatccg tgagcaattt tataaggaaa ttgactttat
     8821 tcatcgtaag tggccagatg ttcagaagta tctggtttat tttcaaaatt ttaccaacac
     8881 ccatgaaaag gtggaagtta ttcgagagcg ttatgaacag gctatcaatg agccaggtgt
     8941 ggtaggaatc aatattggaa cgcgcccaga ctgtttacca gacgaaacca tcgaatattt
     9001 ggctgagtta tcggagtgca tgcatgtgac ggttgaattg ggcttgcaaa ctacttatga
     9061 agcaacctct gacctgatta accgtgcgca ttcttatgaa ttgtaggtgg aaacggtcaa
     9121 gcgtttgaga aagtatccaa aaattgagat tgtttcccat ttgatcaatg gtttgcctgg
     9181 tgaaacccat gagatgatgg ttgaaaatgt ccgccgttgt gtcacggata acgatattca
     9241 agggattaaa ctgcatttgc tccatcttat gacaaatact cgtatgcaac gagattacca
     9301 tgaggggcgt ttacaattga tgagtcagga cgaatatgtc agggtcatct gtgaccaact
     9361 ggaaattatt cccaaacata tcgtcatcca tcgaattaca ggagatgcgc ctagggatat
     9421 gctgcttggg cctatgtgga gcctcaataa atgggaagct ctcaacagca ttgagatgga
     9481 gatgcgacgt cgtggaagtg ttcaaggatg caaggctgta aaacaggagt ttgaaaatga
     9541 aaagaccact tgagatggca catgattttt tggctgaggt cgtgacaaaa gaggatgtcg
     9601 tagtggatgc gactatggga aatggtcatg acacgctttt tttagccaag ctagccaagc
     9661 aagtctatgc ctttgatatt cagaagcaag ccttggaaaa gacccaagag cgtttgcatc
     9721 aggctgactt gacaaatgcc cagttaatct tgcaaggcca tgagacactg gaccagtttg
     9781 tgataaaagc taaggcaggg atttttaatc tgggctattt gccgtcagct gataagtctg
     9841 tcatcacccg accgcagaca acgattgagg cattagaaaa gctatgtggc ttacttgtca
     9901 aaggtggacg aattgctatt atgatttact atggtcatga aggaggcgat ctcgagagag
     9961 atgctgtctt ggattttgtg atccagttga accaacaaga gtacacagct gccatttacc
    10021 gaactttaaa ccaagtcaac aacccgccgt ttttagtgat gattgaaaaa ttagagagat
    10081 acagacatgg ataaacaata cctacacgaa aagctggatg ccatgcgcca gaattttgtt
    10141 gaatcaaccc accacgaacg atcggtgggc gtgctagacc aagcgcatat gagcaaaaaa
    10201 atgcttaaaa tcaagaaaaa attagttgct cttgaaatgg aacggtgcca gagaaaaatt
    10261 gagcacaaag actgttccaa gattgaccaa aaaatcaaag agcagaagga gatatttgaa
    10321 tcctgttgta aaaaagatta aggaggacgt gcgtggaatt actgatttac ctcatcctat
    10381 ttttactggt tttgattgtc tcaagtacaa ccaataagct cctgcccttt ttgcctctcc
    10441 ctttggtgca gattcttttg ggaattgtga ttggtctctt tttacccaat actgactttc
    10501 accttaatac ggagttgttt ttggcactgg ttatcggacc cttgcttttc cgagaggctg
    10561 aagaagcaga tgttacggct attttaaaac actggcgaat cattgtttat ctcatatttc
    10621 cagtgatttt tatctcgacc ttgagtttgg gtggcttggc ccatcttctt tggttcagcc
    10681 ttcccttggc agcttgcttg gctgttgggg cagcccttgg tcctacggac ttggtggcct
    10741 ttgcctctct ttcggagcgt tttagctttc ctaagcgcgt gtccaatatt cttaagggcg
    10801 aaggactctt gaatgatgct tctggtttgg tggcttttca ggtagctttg acagcttgga
    10861 caactggagc tttttctctg gggcaagcta gcagttcgct catcttttca atcctaggcg
    10921 gttttttaat tggattttta acggccatga ccaaccgctt cctccatacc ttcttgctaa
    10981 gtgtgcgcgc aacggatatt gccagtgaac ttttattaga attgagtttg cctctagtga
    11041 ccttctttct ggcagaagaa gttcatgttt caggtattat tgccgtcgta gttgctggaa
    11101 ttttaaaggc aagtcgcttc aagaaaatca cgctcctcga agcccaagtg gatacggtga
    11161 ccgagacggt ctggcataca gtgaccttta tgctcaacgg ttctgtcttt gtgattttag
    11221 ggatggagtt ggaaatgata gcagaaccta tcttgaccaa tccaatctat aatcctctac
    11281 ttttattgct atctctcatc gcccttacct ttgtcctctt tgtcattcgt tttattatga
    11341 tctatggcta ttatgcctat agaacccgac gcctcaagaa aaagctaaat aagtatatga
    11401 aggacatgtt tctcttgacc ttttcaggtg ttaagggaac ggtgtcgatt gctacgattc
    11461 tcttgatacc aagtaatcta gaacaggagt atcctctttt gcttttcctt gttgcaggtg
    11521 tgacgcttgt cagcttttta acaggtctct tggtcttgcc tcatctttct gatgaagagg
    11581 aagaaagcaa ggattatctc atgcatatcg ccattttgaa tgaagtaacg ctagagttgg
    11641 aaaaagagtt ggaagacacc agaaataaac ttcccctcta tgcggctatt gacaattatc
    11701 atggacgtat tgaaaatctc attttaagcc aagaaaacca ggatgatcaa gaagattggg
    11761 ctgctttgaa actcttgatt cttagtattg aaagtgatgg tttggaacag gcctatgaag
    11821 aggggaacat tagcaatcgt gcttaccgag tttaccaacg ttatctgaaa aatatagaac
    11881 aaggaatcaa tcgtaaactt gcctcaagac tgacctatta ttttcttgtt tccttgagga
    11941 ttttacgttt tctccttcat gaagttttta ctcttggaaa gaccttccgt agctggaagg
    12001 acaaggagca aagccgtctc cgtgctcttg attatgacca aattgcagag ctctatcttg
    12061 ccaatacaga gatgattatt gaaagtttgg aaaacctgaa gggagtctac agacgctctt
    12121 tgattagttt tatgcaggag tctcgtcttc gagaaacagc tattatcagc agtggtgcct
    12181 ttgtcgaacg ggttatcaat cgtgtcaaac ccaacaatat cgatgaaatg ctgagaggct
    12241 attatctgga gcgcaagttg attttcgaat acgaagaaaa acgattgatt acgactaagt
    12301 atgccaagaa attacgacaa aatgtaaata acttagagaa ctattccttg aaggaagctg
    12361 ccaataccct gccgtatgat atggtggaat tggtaagaag aaattagtta atactcttcg
    12421 aaaatctctt caaaccacgt cagcgtcgcc ttggattata tatgtgactg acttcgtcag
    12481 tttcatctac aacctcaaag cagggctttg agcaacctgc ggctagcttc ctagtttgct
    12541 ctttgatttt cattgagtat aagattataa atgaaggagt atgacatgaa aaagtggtgg
    12601 aaagagctga tagacaagcc tttattaaaa gcttttttgc attattatca agcatcagat
    12661 agtgagttga ccagtgtcgc agtagcctac tattggttga tttcgatttt ccccctgctt
    12721 ttggtggtgg tcaatatcct cccctatttt cagattcctg tgggagaatt tctgtgcttt
    12781 atgaaagacg ttctgccccc aagcctctat gaaggtgtgg aaaaaatagc cagagaagtt
    12841 ttgacgcaac cttcaacagg tttattgagt ttttctgttt tatcggcgtt atggagtttt
    12901 tcaaaatcta tgaatttctt gcaaaaagct tttaacaagg cttatggcgt cgaaaagagt
    12961 cgtggactta tttcccatca gatgctaagt ctcctagtca gttttggctt gcagctcctc
    13021 tttgcgtttg ccttgttttt gatcttattt ggtcagatga ttttggcttt acttgctcat
    13081 tattggacaa aagatggcat tatctatcag gctttacaag ggttggcagg tcctctgatt
    13141 tacgccctcc tctttgctat cttggtcatg ctttattatt ttcttcccaa tctatctaac
    13201 aggaaaatta gctataccct accaggcagt gcctttgttc tcttagtgat tttaggttta
    13261 ctaactctgt tctctagtta tctcaattac tatgtccatc atttggtgga tgtccgaatt
    13321 ttaggttccg ttcttcttgt tgttatgatg ttttggttta tcttgattgc taaaattgtt
    13381 atcctaggcg cggttatcaa tgccagtatg cagagtttga aagatccggt ctttaaaaaa
    13441 gactaactat ttatccatta caaaagcgca tagtatcaaa actttataga accttgatac
    13501 tatgcgcttt tgtgctttga cagttttttg tatagttttt gtccaagatt tctaaatcat
    13561 ctgattaaat tcctattttc ccctatcatt gtccctgttt tttcgaaaat ggaaggagta
    13621 taataaatct atcaataaaa tgataggagg aactttatgg gtcatatttt cttttttcta
    13681 agtgtctttt tggcagggat tctatccttc ttttctcctt gtatcttacc tttgttaccg
    13741 gtctatacag gagtgttact agatgataag gatggtgctc aggcttctag cggcaaattt
    13801 tcaatctcag ttactagttt attacgaact ctggccttta tagcaggaat ttcctttata
    13861 tttattttgt tgggctatgg agctggtttt ttaggcgatt tgctttatgc ttcttggttc
    13921 caatatctta ctggggcaat tattatcctt cttggtttgc accaaatgga gattctacac
    13981 tttaaggggc tttataagga aaagaggcta caactgcaag gacaggggca aaatggtaag
    14041 ggctatagtc aggcattttt attgggcttg acctttagtt ttgcttggac gccttgcgtg
    14101 gggccggttc tggggtctgt tttggccttg gcggcttcag gtggttcagg agcttggcag
    14161 ggagctggtc tcatgttggt gtatacgctg ggcttggcgc taccattctt gcttctagct
    14221 ctgacctcta gttatgtttt gaaacatttc cgaaaacttc atccctatct cggaatcctc
    14281 aaaaaagtgg gtggttttct cattattgtg atgggactct tggttctgtt tggaaatgct
    14341 tcaattttaa gtcaattatt tgaataaaat ggaaaggaat atcaatatga aaaaatggca
    14401 aacatgtgtt cttggagcag gttcgctcct ttgtttgacg gcttgttcag gcaagtccgt
    14461 gactagtgaa caccaaacga aagatgaaat gaagacggag cagacagcta gtaaaacaag
    14521 cgcagctaaa gggaaagagg tggctgattt tgaattgatg ggagtagatg gcaagaccta
    14581 ccgtttatct gattacaagg gcaagaaagt ctatctcaaa ttctgggctt cttggtgttc
    14641 catctgtctg gctagtcttc cagatacgga tgagattgct aaagaagctg gtgatgacta
    14701 tgtggtcttg acagtagtgt caccaggaca taagggagag caatctgaag cggactttaa
    14761 gaattggtat aagggattgg attataaaaa tctcccagtc ctagttgacc catcaggcaa
    14821 acttttggaa acttatggtg tccgttctta cccaacccaa gcctttatag acaaagaagg
    14881 caagctggtc aaaacacatc caggattcat ggaaaaagat gcaattttgc aaactttgaa
    14941 ggaattagcc taggaggtgt cttatgaatg ataagttaaa aatcttcttg ttgctaggag
    15001 tattttttct agccataacc ggtttctatg ttctattgat acgaaatgca gggcagacag
    15061 atgcctcgca aattgaaaag gcggcagtta gccaaggagg aaaagcagtg aaaaaaacag
    15121 aaattagtaa agacgcagac ttgcacgaaa tttatctagc tggaggttgt ttctggggag
    15181 tggaggaata tttctcacgc gttcccgggg tgacggatgc cgtttcaggc tatgcaaatg
    15241 gtagaggaga aacaaccaag tacgaattga ttaaccaaac aggtcatgca gaaaccgtcc
    15301 atgtcaccta tgatgccaag caaatttctc tcaaggaaat cctgcttcac tatttccgca
    15361 ttatcaatcc aaccagcaaa aataaacaag gaaatgatgt ggggacccag taccgtactg
    15421 gtgtttatta cacagatgac aaggatttgg aagtgattaa ccaagtcttt gatgaggtgg
    15481 ctaagaaata cgatcaacct ctagcagttg aaaaggaaaa cttgaagaat tttgtggtgg
    15541 ctgaggatta ccatcaagac tatctcaaga aaaatccaaa tggctactgc catatcaatg
    15601 ttaatcaggc ggcctatcct gtcattgatg ccagcaaata tccaaaacca agtgatgagg
    15661 aattgaaaaa gaccctgtca cctgaggagt atgcagttac ccaggaaaat caaacagaac
    15721 gagctttctc aaaccgttac tgggataaat ttgaatccgg tatctatgtg gatatagcaa
    15781 ctggggaacc tctcttttca tcaaaagaca aatttgagtc tggttgtggc tggcctagtt
    15841 ttacccaacc catcagtcca gatgttgtca cctacaagga agataagtcc tacaatatga
    15901 cgcgtatgga agtgcggagc cgagtaggag attctcacct tgggcatgtc tttacggatg
    15961 gtccacagga caagggcggc ttacgttact gtatcaatag cctctctatc cgctttattc
    16021 ccaaagacca aatggaagaa aaaggctacg cttatttact agattatgtt gattaatact
    16081 cttcgaaaat ctcttcaaac cacgtcagcg tcgccttacc gtatgtaggg tt
//
LOCUS       DAVBDR010000047        16004 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.047, whole genome shotgun sequence.
ACCESSION   DAVBDR010000047 DAVBDR010000000
VERSION     DAVBDR010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16004)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16004)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16004
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.047"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            complement(<1..1079)
                     /locus_tag="VQ540_001569"
     CDS             complement(<1..1079)
                     /locus_tag="VQ540_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HET2545348.1"
                     /translation="MEQLHFITKLLDIKDTNIQIIDVVNRDSHKEIIAKLDYDAPSCP
                     ECGNQLKKYDFQKPSKIPYLETTGMPTRILLRKRRFKCYHCSKMMVAETPLVKKNHQI
                     PRIINQKIAQKLIEKISMTDIAHQLAISTSTVIRKLNDFHFEHDFSRLPKIMSWDEYA
                     FTKGKMSFIAQDFDNLNIITVLEGRTQAVIRNHFLRYDRAVRCQVKIITMDMFSPYYD
                     LAKQLFPCAKIVLDRFHIIQHLSRAMSRFRVQIMNQFERKSHEYKAIKRYWKLIQQDS
                     RKLSDKRFYRPTFRMHLTNKEILDKILSYSEDLKHHYQIYQLLLFHFQNKDPEKFFGL
                     IEDNLKQVHPLFQTVFKTFLKNKEK"
     gene            1165..1866
                     /locus_tag="VQ540_001570"
     CDS             1165..1866
                     /locus_tag="VQ540_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001827799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit R"
                     /protein_id="HET2545349.1"
                     /translation="MYSGFTHYKYYRAEIIRKVQEPEFWKEVNLSDLEKIRLAIRDLL
                     QFLDKTDRKPYYVNFEDRILSTVHETTAFLQVNDLRSYNEKVEHYLKTHLDEESISKL
                     YHNKKLTSDDMLALEKLLWEKLGSKADYQSHYENKAIPRLVREIIGLDRESANRIFSK
                     FLSDENLNARQISFVKLIVDYIVENGFLETKVLTQEPFKSYGSVQLLFQHQLPVLRNI
                     VQIIELINNRAGEAA"
     gene            complement(2266..3612)
                     /locus_tag="VQ540_001571"
                     /pseudo
     CDS             complement(2266..3612)
                     /locus_tag="VQ540_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808790.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1380-like element ISSpn5 family transposase"
     gene            3674..3868
                     /locus_tag="VQ540_001572"
     CDS             3674..3868
                     /locus_tag="VQ540_001572"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2545350.1"
                     /translation="MSSKKHPLGEKRNHTGSKLRQGFWMVFRLGVNNWGFKEIENKKP
                     SKNSIAGENEIILNENQRAN"
     gene            3846..4046
                     /locus_tag="VQ540_001573"
     CDS             3846..4046
                     /locus_tag="VQ540_001573"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2545351.1"
                     /translation="MKIKEQTRKLAAGCSKHCFEVVDKTDEVSSKHGFEVVDETDEVS
                     NHTYGKATLTRIEEIFEEYKSS"
     gene            complement(4126..4571)
                     /locus_tag="VQ540_001574"
                     /pseudo
     CDS             complement(4126..4571)
                     /locus_tag="VQ540_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000547411.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            4579..4722
                     /locus_tag="VQ540_001575"
     CDS             4579..4722
                     /locus_tag="VQ540_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2545352.1"
                     /translation="MAERFWENLSIILADRNISWIELTRKMFAGEFHYPSELNRLYQK
                     IRH"
     gene            4815..5402
                     /locus_tag="VQ540_001576"
     CDS             4815..5402
                     /locus_tag="VQ540_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000821297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET2545353.1"
                     /translation="MKRIIPVYIFQQVNVLLVSLYLLKFLCSDELTILQILYGASLIS
                     FLWMYGQRKQVIKVNMKTRIQWLGIGFVSLLIISLCFSLIHAQESTNQANLIGLQHQI
                     PWFSFLLFLINASMVEEFLYREILWNLVRKLDIRVALTSVLFALAHHPGTIIAWCLYV
                     SLGMFLGLVRYKLDLWGSMGLHLVWNLLVYSLLLF"
     gene            5802..6611
                     /locus_tag="VQ540_001577"
     CDS             5802..6611
                     /locus_tag="VQ540_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000926538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HET2545354.1"
                     /translation="MLLQKELIPMIEANLPNMAYAEKDIAKFFLKQQPLNNYSCKALC
                     ECLNVSKATLTRFAKKCGFKGFRQFIFKYQEMIREKEKLALYTEATEKVLSDYEEMLR
                     KTYTVLDEVQLERIAEMIETAERVYLYGKVSSVLALQEMKMRFMRLGVIGEVLSDEDM
                     ILWNSLLLNENCLVIGASVSGQTDIVLEGLQKAADKGAKTVLMTTRKFDEEDCFFDEL
                     LLLASTNHLSYGNRISPQFPILLITDCLFSHYLESPERQYYYNQTIIHKEE"
     gene            6616..7317
                     /locus_tag="VQ540_001578"
     CDS             6616..7317
                     /locus_tag="VQ540_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HET2545355.1"
                     /translation="MSQIWTKEKFISQVHGGVIVSCQALPGEPLYNEEFSLMPFMAKA
                     ALEAGAVGIRANSVRDIKAIQKVVDLPIIGIIKRDYPPQEPYITATMKEVDELVECGT
                     TVIAFDATLRPRYDGLVINEFIKKIKEKYPNQLLMADVSNFDEGLYAFKSGVDFVGTT
                     LSGYTSTSVQSDEPDFELMKKLADFNIPVIAEGKIHYPEQLKKAYSLGVTSVVIGGAI
                     TRPKEIAQRFINVIK"
     gene            7342..8259
                     /locus_tag="VQ540_001579"
     CDS             7342..8259
                     /locus_tag="VQ540_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate lyase"
                     /protein_id="HET2545356.1"
                     /translation="MKDLTKYKGVIPAFYACYDENGEISQERVKSLVQYFIDKGVKGI
                     YVNGSSGECIYQSVEDRKQIIEAVMEVAKGKLTVINHVACNNTKDSIELAKHSESVGV
                     DAIAAIPPIYFKLPEYSIAAYWNAMSEAAPNTDFIIYNIPQLAGVALTGSLYATMRQN
                     PRVIGVKNSSMPVQDIQMFVAAGGEDYIVFNGPDEQYLGGRLMGAEAGIGGTYGVMPD
                     LFLKLESLIQERDLDTAKKLQYAINEVIYKMISGKANMYAVAKEVLRLNEKLDLGSVR
                     QPLEALAEGDLEVAKQAAELIQQARKEFL"
     gene            8287..9828
                     /locus_tag="VQ540_001580"
     CDS             8287..9828
                     /locus_tag="VQ540_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000537364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:solute symporter"
                     /protein_id="HET2545357.1"
                     /translation="MGTTGFTIIDLIILIVYLLAVLVAGIYFSKKEMKGKEFFKGDGS
                     VPWYVTSVSIFATMLSPISFLGLAGNSYAGSWILWFAQLGMVVAIPLTIRFILPIFAR
                     IDIDTAYDYLDKRFNSKALRIISALLFIIYQLGRMSIIMYLPSAGLSVLTGIDINILI
                     ILMGAVAIVYSYTGGLKSVLWTDFIQGVILISGVVLALFVLMANIKGGFGAVAETLAN
                     GKFLAANEKLFDPNLLSNSIFLIVMGSGFTILSSYASSQDLVQRFTTTQNIKKLNKML
                     FTNGVLSLATATVFYLIGTGLYVFYQVQNAGSAASNIPQDQIFMYFIAYQLPVGITGL
                     ILAAIYAASQSTISTGLNSVATSWTLDIQDVISKNMSDDRRTKIAQFVSLAVGLFSIG
                     VSIVMAHSDIKSAYEWFNSFMGLVLGLLGGVFILGFVSKKANKQGAYAALIVSTIVMV
                     FIKYFLPPTAVSYWAYSLISISVSVVSGYIVSVLTGNKVSAPKYTTIHDIPEIKADSS
                     WEVRH"
     gene            9847..10305
                     /locus_tag="VQ540_001581"
     CDS             9847..10305
                     /locus_tag="VQ540_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HET2545358.1"
                     /translation="MIISEQSDFRRYASINKHFSKVCDFLENTNLTDLVDGKVDIDGE
                     NVFANCMIYLADGVPGDIFETHKKYLDIHIVVENTEKMAVTSPVRAQSRVPFSEEKDI
                     AFYDSKDYQIVELLPGNMLVTFEEDLHQPKIHCNDEPVKKLVIKVLNEEK"
     gene            10307..12529
                     /locus_tag="VQ540_001582"
     CDS             10307..12529
                     /locus_tag="VQ540_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exo-alpha-sialidase"
                     /protein_id="HET2545359.1"
                     /translation="MKKNIKQYVTLGTAVVLSAFVANSVAAQETETSEVSTPELVQPV
                     APTTPISEVQPKSGNSSEVTVQPRTVETTVKDPSSATEETPVLEKNNVTLTGGGENVT
                     NELKDKFTSGDFTVVIKYNQSSEKGLQALFGISNSKPGQQNSYVDVFLRDNGELGMEA
                     RDTSSNKNHLVSRPASVWGKYKQEAVTNTVAVVADSVKKTYSLYANGTKVVEKKVDNF
                     LNIKDIKGIDYYMLGGVKRAGKTAFGFNGTLENIKFFNSALDEETVKKMTTNAVTGHL
                     IYTANDTTGSNYFRIPVLYTFSNGRVFSSIDARYGGTHDFLNKINIATSYSDDNGKTW
                     TKPKLTLAFDDFAPVPLEWPRDVGGRDLQISGGATYIDSVIVEKNNKQVLMFADVMPA
                     GVSFREATRKDSGYKQIDGNYYLKLKKQGDTDYNYTIRENGTVYDDRTNRPTEFSVDK
                     NFGIKQNGNYLTVEQYSVSFKNNKKTEYRNGTHVHMNIFYKDALFKVVPTNYIAYISS
                     NDHGESWSAPTLLPPIMGLNRNAPYLGPGRGIIESSTGRILIPSYTGKESAFIYSDDN
                     GASWKVKVVPLPSSWSAEAQFVELSPGVIQAYMRTNNGKIAYLTSTDAGTTWSAPEYL
                     KFVSNPSYGTQLSIINYSQLIDGKKAVILSTPNSTNGRKHGQIWIGLINDDNTIDWRY
                     HHDVDYSNYGYSYSTLTELPNHEIGLMFEKFDSWSRNELHMKNVVPYITFKIEDLKKN
                     "
     gene            12569..13678
                     /locus_tag="VQ540_001583"
     CDS             12569..13678
                     /locus_tag="VQ540_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HET2545360.1"
                     /translation="MVNYGIVGAGYFGADLARSMNKIEDAKVVAVFDPNHGEEVAQEL
                     GSDVCASLDELVAREDIDCVIVASPSYLHREPVVKAAQHGKHVFCEKPIALSYEDCKA
                     MVDACKENNVIFMAGHIMNFFNGVHHAKELITQGKIGKVLYCHAARTGWEEQQPTVSW
                     KKLRSQSGGHLYHHIHELDCIQFIMGGLPEKATMVGGNVYHKGENFGDEDDMLIVNLE
                     YSDDRYAVLEYGNAFRWGEHYVLIQGTEGAIKLDLFNTGGTLRVKGEGESHFLVHETQ
                     EEDDDRTAIYTGRGMDGAIAYGKPGVRCPLWLQTCIDKEMEYLHDIIKGGEITEEYEK
                     LLNGVAALESIATADACTLSVKEDRKVSLSEITNA"
     gene            13835..14725
                     /locus_tag="VQ540_001584"
     CDS             13835..14725
                     /locus_tag="VQ540_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HET2545361.1"
                     /translation="MKIIGIDIGGTTIKADLYNEFGTSLNQFKEIETIIDYDLGTNQI
                     LNQVCDLIGEYILNHSIDGVGISTAGVVNANTGEIIYTGYTIPGYIGVNFTFEIEKRF
                     GLSTFVENDVNCAALGELWKGQAKDKKNVVMVTIGTGIGGSIIVNGQIVNGFNYTAGE
                     VGYIPVGNSDWQSKASTTALIHLYQKKSLKTNQTGRTFFTDLRAGDKVAKETFEIFVE
                     NLTKGLLTITYLLNPEILILGGGILAKKDILLPEIQSSLAKNAMDNRFLPKNLVAATL
                     GNEAGRIGAVKNFLDRISNK"
     gene            14750..15073
                     /locus_tag="VQ540_001585"
     CDS             14750..15073
                     /locus_tag="VQ540_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2545362.1"
                     /translation="MTNSVFSTMQDIENVATDIIKSYDNEIYTYKAVSQEELEKLEKS
                     YDEKSHEELVSIESNLEMKQQNLIDEVNKTIKENYEKIQYISSSRRGEFVEKIIGRVV
                     EKYGY"
     gene            15063..>16004
                     /locus_tag="VQ540_001586"
     CDS             15063..>16004
                     /locus_tag="VQ540_001586"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018351.1"
                     /note="Produces ATP from ADP in the presence of a proton
                     gradient across the membrane. Subunit I is part of the
                     membrane proton channel; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HET2545363.1"
                     /translation="MAISQMKRISLLFSKSSLDDVLKTIQELESVQFRDLKVQDNWSE
                     ALEKDEVVFPTIQISHTSNSNHGVIEGNDALIYLMNQQQYLEATVEKLQEYLPKENTF
                     KLLQQPPITTSYEELEKFGKANVAEGVLKKVNRQINRVHELERHIQSNNEEIERLIKW
                     EKLEIIPAHLEQFFFCKGKVGTIPRTVDNRLYNSFLENNIEVQEIFSNDREYGVVVFY
                     QSSCSIDFDEYLFEPFDYSRKELPKQRVVDLDQENMQLITEKENIIASLQDSKNNLID
                     LQWQIDYILSIYARQISKNNLLSTPHLVALEGWIEETR"
BASE COUNT         5323 a         2447 c         3178 g         5056 t
ORIGIN      
        1 attttctctt tgttctttag aaaggtttta aagacagtct gaaaaagagg atgaacctgc
       61 ttcagattgt cctcaatgag tccgaaaaat ttctcagggt ctttgttctg aaagtgaaaa
      121 agtaagagtt gatagatctg atagtggtgt ttcaagtctt ctgaatagct taaaatcttg
      181 tcaagaattt ctttatttgt taagtgcatg cgaaaagtag ggcgataaaa acgtttatcg
      241 ctcaatttac gactatcctg ttggatgagt ttccagtaac gcttgatagc cttgtattca
      301 tgagattttc gttcaaactg attcataatt tgaacacgaa aacgactcat ggcacggctg
      361 agatgttgga taatatggaa acgatctaga acgattttag cacacggaaa aagctgttta
      421 gccaagtcat agtaaggact aaacatatcc atcgtaatga ttttcacttg acaacgaacg
      481 gctctatcgt agcgaagaaa gtgatttcgg atgacagctt gtgttctgcc ttcaagaaca
      541 gtgataatat taagattatc aaaatcttgc gcaatgaaac tcatctttcc cttagtgaag
      601 gcatactcat cccaagacat aatctttgga agccgagaaa aatcatgctc aaagtgaaag
      661 tcattgagct tgcgaatgac agttgaagtt gaaatggcca gctgatgggc aatatcagtc
      721 atagaaattt tttcaattaa cttttgagca attttttggt tgatgatacg agggatttgg
      781 tgatttttct ttaccagggg agtctcagca accatcattt ttgaacagtg atagcacttg
      841 aaacggcgtt ttctaaggag aattctagta ggcataccag tcgtttcaag ataaggaatt
      901 ttagaaggtt tttgaaagtc atatttcttc aattggtttc cgcactcagg gcaagatggg
      961 gcgtcgtagt ccagtttggc gatgatttcc ttgtgtgaat ccctattgac gacatctata
     1021 atttggatat ttgtgtcttt gatatcgagt agttttgtga taaaatgtaa ttgttccata
     1081 tgaatctttc taatgagttg tttggtcgct tttcattata gatcttatgg gacttttttt
     1141 ctacaataaa ataggctcca taatatctat agtggattta cccactacaa atattataga
     1201 gccgaaatta tcaggaaagt acaggagcct gaattttgga aagaagttaa cttgtctgat
     1261 ttggaaaaaa ttcgtcttgc tattcgagat ttattacagt ttttggataa aacagaccgt
     1321 aaaccctact atgttaactt tgaagatcgt atactctcca ctgttcacga gaccacagca
     1381 tttttgcagg tcaacgatct tcggtcttac aatgaaaaag ttgagcatta tttgaaaact
     1441 catctggatg aggagtccat ttctaagcta taccataata aaaagttgac atctgatgat
     1501 atgcttgcac ttgaaaaatt gctttgggaa aaattaggta gtaaagcaga ctaccaaagt
     1561 cattatgaaa ataaggcaat tccgagattg gttcgtgaga ttattggctt agatagagag
     1621 tctgccaatc gtattttctc taaatttttg tcggatgaga atcttaatgc caggcagatt
     1681 tcatttgtaa aattgattgt agactacatt gtagaaaatg gttttttaga gacgaaagtg
     1741 ttaacgcaag agccgtttaa atcttatggt tctgttcaac tactcttcca acaccaacta
     1801 ccagtacttc gtaatattgt tcaaatcatt gaacttatca ataatcgagc tggagaagcg
     1861 gcttaaattc taaagtgatt gccatgctga gactcattta aaattaaaaa gagtagaaat
     1921 ttatgctata tatgagaagt tttattagga agaatgtcat cgttttccta gaatacagta
     1981 tcagttgtta agtggttgat aaatttcaaa gtagatactt gtaccacgat gtttgttgat
     2041 cgagttatta acaaaagagc tactttgatt ttaacccaaa tcattcatac ctctctcaac
     2101 tagatgtaac ttacaaaacc cctgacctca tgagccactt tcttcctcct catgaggtca
     2161 gttttacttt ctgctgttcc agtatcgttt ttcctcgcta gatttcctca aaagggcaga
     2221 ctcctccctt ggtgcgtcac acgatttttt catctcgact gttctttaat gcatcattaa
     2281 cgacgctttt cttccaggtg gttcataagg aacaggaaga ttcaggttga cttttctaat
     2341 cctagaataa agtgctgaaa acaattcgga ataggcatag agactagaca atttgaggag
     2401 ctgcttgcgt cctgttcgaa cacattttcc taccacgtga agaaaaagat ggcggaagcg
     2461 tttgattgtt aaagtttgga agtcacctcc agctagatgt ttgagaaaaa gatagagatt
     2521 gtaggcgata cagctcatca tcatacgaac ttcgtttttg attaaggttg aactatccgt
     2581 tttatcgcca aaaaatccct ccttcatctc cttgatgaaa ttctcggctt gaccacgtcc
     2641 acgataaagc tgaaactggt cttggcttgt tccactcgtc atatttgtaa cgagagaaat
     2701 aacatcgtag aacaagtttc cttcttttcg ttcagagaac tggcagacac gacgcttgtg
     2761 cgaccaagat cctgcttgat agagagtttc tgagtaggcg gagtggggca agatggttaa
     2821 gtcctcatcc tgtgggcaag ggagggaaag gtctccaaga cggctcagaa cagtattttt
     2881 cttgagtttt atgagttagt attgccctgt tttttcaatt aaatcgtata atttgggggt
     2941 cgcaaagcca ctatccattc gaaagagaag ttgattaaac cgttctaaaa caggtgtgat
     3001 aaagctgtct gcctcttcag aacaataacg attaccagga cgaagctggg cattgaaaca
     3061 ataacctgtc ttcccctcga aagcataaag aggatgatag ccatgagcac gatagtgggc
     3121 gttataagca acaccttctt gcttgccata agttgtgaaa tgggtagaat cgatatctac
     3181 aatgagttgg tttagctggt gaaactgtaa aaagaattcg accaattcaa ggttgaggca
     3241 tcgcaaacta tggactgttt cctcgtcagt tctggaaaga aaacgggata aggttggctg
     3301 tgaagcaagc tgccctcctt ccaacaattt tggaaagtag gcatcagctg acaattcttt
     3361 acaagcatag tccgttccat agcctgttaa cagttgaaag aggaactgga caaggatatc
     3421 tgaatccgaa taacgacagt agcggcgttg gtcattcgtt actaaatact tagaaatccg
     3481 ctcttttagt ttcaactggg aaaaaagttc ctgaaaaaag ataagaccac catactgggt
     3541 taaatgacct ccatcgaaag atagttggta aaaagacttg ttttggaagt gatgatttgg
     3601 taaactgttc atgtgagttt cctttctttt tgtgtttttt tctacactta taccataaag
     3661 gggaaattct tttttgtcta gtaaaaaaca cccattgggt gaaaaaagaa accatacagg
     3721 atctaagcta aggcaaggat tctggatggt ttttagatta ggggtgaata attggggttt
     3781 taaagaaata gaaaacaaaa agccgagcaa gaattcaatt gcaggagaaa atgaaataat
     3841 actcaatgaa aatcaaagag caaactagga aactagctgc aggctgctca aaacactgtt
     3901 ttgaggttgt agataagact gacgaagtca gctcaaaaca tggttttgag gttgtagatg
     3961 aaactgacga agtcagtaac catacctacg gcaaggcgac gttgacgcgg attgaagaga
     4021 ttttcgaaga gtataaatct tcctaggata aagcaaagag cctgggacaa aatagttctc
     4081 gaccacaaaa aagctagaga tttccaattg tggaacttta gctttttaat tttgagtcgt
     4141 tctcttattg tattttagga ggttattggc cataagtacc aatcccatgt caattctcac
     4201 ttgacgcttg cccctcagat tacatctctt gtaacccaaa caagccttta tctgcccaaa
     4261 gacaggtgac attctttagc tttcaagttt tgatagcctt cgttcatata cagtcccttt
     4321 tgaggggctg attcaggttc gtcggcgtag taaaccttga tttcttgttt aaagtctgtc
     4381 tgtgttttct gatgtttggt atggtgaaaa cgataatacc agccatcagg atgtgtatag
     4441 ctatcctcct tgtcattata gtaccaattc gctaagtttc tagctgactg tttatagcct
     4501 ctcttctgtt ccttatcaaa catggcatat ttaatcagat ggtttacctc cttttcatct
     4561 aactaaagga gaagcaatat ggctgaacga ttttgggaga acttgtccat tattttggct
     4621 gacagaaata tcagctggat tgagttaacc agaaaaatgt ttgcgggaga gtttcactat
     4681 ccaagtgaat tgaatcgttt gtatcaaaag attcgccact agaagatgga acaacgaatg
     4741 cctcaaagtc catgggtaga aaggattgtg caggtattag atttagatta tgaagattta
     4801 tttcggaggt aattatgaaa agaataattc cagtttatat attccaacaa gtaaatgtcc
     4861 tattggtatc tctatactta ttgaaatttc tttgtagcga tgagttaact atactacaga
     4921 ttctctatgg agcgtcactc atttcttttt tatggatgta tggtcaacga aaacaagtga
     4981 tcaaggttaa tatgaaaact aggatacaat ggcttggtat tggattcgtt agcctactga
     5041 ttataagtct atgttttagt ctaatccatg cgcaagaaag cacgaatcaa gcaaacttaa
     5101 ttggacttca acatcaaatt ccttggtttt catttttatt gtttttaatc aatgcgagta
     5161 tggttgaaga atttctgtat agagaaattt tatggaactt ggttagaaaa ttagatattc
     5221 gagttgcttt gacaagtgtt ttatttgcct tagcacatca tccaggaacc attatagctt
     5281 ggtgtttgta tgtatcgctg gggatgtttt tagggcttgt acgctacaaa ttggacttat
     5341 ggggcagtat ggggctacat ttggtgtgga acctactagt ttatagtttg ctgctttttt
     5401 aaaataagtg atctgattta tctcataaat cagtagtttt tataggatta tttttaattc
     5461 ggaaacaaaa atgtattaac agcataaaat aaagaaacta ggaacatttt ttttattttt
     5521 tagaaataaa atgttgtata gaaattccga aagaaataat aaaatcaaaa taaaaattaa
     5581 taaaataggt atatttgaac atattgacgt cgacaaatgt tcttgcaaga cataaaatac
     5641 aaataaaaag aataaaaaat ttttatattt ttatatttgt tgttctgtta taaaatgaaa
     5701 gaaattagaa actagtttct aaatcatgaa aaatattgaa aaaaaaaaaa ataagtgtta
     5761 aaataaagaa tgtaaacgtt tacttcaata aaggagctca tatgttactg caaaaagaac
     5821 taattccaat gatagaagct aacttaccaa atatggcata tgctgaaaaa gacattgcta
     5881 aattcttctt aaaacagcaa cctctgaata attattcatg taaggcattg tgcgaatgcc
     5941 ttaatgtatc caaagcaaca ttgactcgat ttgcgaaaaa atgtggtttt aaaggtttta
     6001 gacaattcat tttcaaatac caagagatga ttcgtgagaa agaaaagtta gcattgtata
     6061 cagaggctac agaaaaagtt ttatccgact atgaagaaat gttgagaaaa acttacacgg
     6121 ttcttgatga agttcaactt gagcgtattg ctgagatgat agaaactgct gagcgtgtat
     6181 atctttatgg taaagtaagt tctgttcttg ctttacaaga aatgaagatg agatttatgc
     6241 gtctcggagt cattggtgaa gtattatcag acgaggatat gattttgtgg aatagcttat
     6301 tacttaatga aaattgcctt gtcattggag catccgtttc aggtcaaact gatattgtac
     6361 tagaaggtct tcaaaaagct gcggataaag gcgctaaaac agttttaatg actacaagaa
     6421 aatttgacga agaagattgt ttctttgatg aactattgtt attagcttcg accaatcatc
     6481 tctcgtatgg caatcgcata tcacctcagt ttccaatact tttaattaca gactgcttat
     6541 tctctcatta tctggaaagt ccagagagac aatattatta caatcaaact attatccata
     6601 aggaggaata ataaaatgag tcaaatttgg actaaagaaa aatttataag tcaagtccat
     6661 ggtggagtca ttgtttcttg tcaagcttta cccggtgaac ccctttataa tgaagaattt
     6721 agcttgatgc cttttatggc taaagcagct ttagaggcag gagcagtggg cattcgcgca
     6781 aattctgtgc gtgatattaa agcaattcag aaagtagtag atttaccaat aattggaatt
     6841 atcaaaagag attatccacc tcaagaacca tatattactg ctacgatgaa agaagtagat
     6901 gaacttgtag aatgcggaac aacagtcatt gcatttgatg caactttaag accaagatat
     6961 gatggcttag ttatcaatga atttatcaaa aaaataaaag aaaaatatcc taatcaattg
     7021 ttgatggcgg atgtaagtaa ttttgatgaa ggtctctatg catttaaatc aggcgttgat
     7081 tttgttggta caacattatc agggtacaca agtacaagtg tacaatcaga tgagcctgat
     7141 tttgaactaa tgaaaaaatt ggctgatttt aatattccgg taattgccga aggaaaaatt
     7201 cattatccag aacaattaaa aaaagcttat agtttaggtg ttaccagtgt tgtcattggt
     7261 ggagcgatta cacgtccaaa agaaattgct cagcgattta ttaatgtcat caaataaaaa
     7321 acaatataaa ggagaaatct gatgaaagat ttaactaaat acaaaggcgt tattcctgca
     7381 ttttatgctt gctatgatga aaatggtgaa attagccaag aacgtgtaaa atctctggtg
     7441 caatatttca ttgacaaagg tgtaaaaggt atctatgtaa atggttcttc aggtgaatgt
     7501 atttaccaaa gtgtagaaga tcgtaaacaa attattgaag ctgttatgga agttgctaaa
     7561 ggtaaattaa cagttatcaa ccatgttgca tgtaataaca cgaaagatag tattgaattg
     7621 gcaaaacatt cagaaagtgt tggagtcgat gctattgctg ctatcccacc tatttacttc
     7681 aaattgccag aatattcaat tgcagcatat tggaatgcaa tgagtgaagc tgcgccaaat
     7741 acagatttta tcatttataa tattccacaa ttggcagggg ttgcgttgac tggtagtttg
     7801 tatgcaacaa tgcgtcaaaa tcctcgtgtg attggagtta aaaattcttc tatgcctgta
     7861 caagatattc aaatgtttgt agctgcaggt ggagaagatt acattgtatt caatggtcca
     7921 gatgaacaat atcttggtgg tcgcttgatg ggagcagaag ctggtattgg tggtacttat
     7981 ggcgttatgc cagatttgtt cttgaaattg gaaagtttga ttcaagaacg agatttagat
     8041 actgctaaaa aacttcaata tgctatcaat gaagttatct ataagatgat atcaggtaag
     8101 gcaaatatgt atgctgtagc aaaagaggtt ttgcgtctaa atgaaaaact tgatttaggt
     8161 tctgttcgtc aacccttaga agcattggca gaaggtgact tggaagttgc aaaacaagca
     8221 gcagaactta ttcaacaagc acgaaaagaa tttttataat aaataaaatc aatatggaga
     8281 tatgttatgg gcacaacagg atttacaata attgacttaa ttatcttgat tgtttattta
     8341 cttgcggtgt tggttgcagg tatctatttc tctaaaaaag agatgaaagg aaaagagttc
     8401 ttcaaaggag atggttcggt tccttggtat gttacttcgg tatccatttt tgccacaatg
     8461 ctcagtccga tttccttctt gggactcgct ggtaactctt atgcaggtag ctggatttta
     8521 tggtttgctc aattagggat ggtagtagct attccactga caattcgttt tatcttacct
     8581 atctttgcac ggatagacat cgatacggca tatgattact tggataaacg ttttaattct
     8641 aaagcacttc gtattatttc agcactcttg tttattattt atcaattggg acgtatgtct
     8701 atcattatgt acctcccatc agctggttta tcagtattga caggaattga catcaatatt
     8761 ttgattattt tgatgggtgc agttgcaatt gtttattctt acactggtgg tctaaaatcc
     8821 gtattatgga cagactttat tcaaggtgtg attctgatta gtggtgtcgt tttagcttta
     8881 tttgtactga tggctaatat taaaggtggc tttggtgcag tagcagaaac attagcaaac
     8941 gggaaattcc ttgctgcaaa tgaaaaactt ttcgatccta acttgctttc aaactccatc
     9001 tttttaattg tgatgggttc aggctttaca atcttgtctt cctatgcttc atctcaagat
     9061 ttggttcaac gttttactac aacacaaaat attaagaaac ttaataagat gttgttcaca
     9121 aacggtgtct tgtcacttgc aactgcaaca gtcttttact tgattggtac aggcttgtac
     9181 gtattctatc aagtacaaaa tgcaggtagt gcagctagca atatccctca agaccaaatc
     9241 tttatgtact ttattgcata ccagttacca gtaggtatca caggtttgat tttggcagcg
     9301 atttatgcag catctcaatc aactatttca acaggtttga actctgttgc aacttcatgg
     9361 acattggata ttcaagatgt catttctaaa aatatgtcag acgatcgtcg tacgaaaatt
     9421 gcacaattcg tatctctagc agtaggttta ttctcaattg gtgtttccat tgtcatggct
     9481 cactcagata ttaaatctgc atacgaatgg ttcaatagct tcatgggact tgtacttggt
     9541 ctacttggtg gtgtatttat tcttggattt gtttctaaaa aagcaaataa acaaggtgct
     9601 tatgcagcgc tgattgtatc aactatcgtc atggtattta ttaaatactt ccttcctcca
     9661 acagctgtga gctactgggc atattcattg atttcaatct ctgtatcagt agtttcaggt
     9721 tatattgtat ctgttcttac tggaaataaa gtatctgcac ctaaatatac aacgattcat
     9781 gatattccag aaattaaagc ggattcaagt tgggaagttc gtcactaata gaaaagagaa
     9841 aataatatga ttatttctga acaatctgat tttagacgat atgcttctat caataaacat
     9901 ttttcaaaag tctgtgattt tttagaaaat acaaatttga cagatttagt tgatggaaaa
     9961 gttgatattg acggggaaaa tgtttttgca aattgtatga tctatctagc tgatggagtc
    10021 ccaggagata tttttgaaac tcataagaaa tatttagata ttcatattgt tgttgaaaat
    10081 actgaaaaaa tggcagtaac ttccccagtt cgtgcccagt cacgtgtacc ttttagcgaa
    10141 gaaaaggata ttgcttttta cgatagcaaa gactatcaaa ttgttgaatt gcttccaggg
    10201 aatatgttgg tgacttttga agaagatctt caccaaccaa agattcattg caatgatgag
    10261 cctgttaaaa aacttgttat taaagtttta aacgaggaaa aataaaatga aaaaaaatat
    10321 taaacaatac gtaaccttag gtactgcagt ggtattatca gcatttgttg ctaactcagt
    10381 tgcagctcag gagactgaaa cttctgaagt atcaacacca gagttggtgc aacctgttgc
    10441 accaacgact ccgatttcgg aagtacaacc taaatcgggt aactcttcgg aagttactgt
    10501 acaacctaga acagtcgaaa ctactgttaa ggatccatct tctgcaacgg aagaaactcc
    10561 tgtcttagaa aaaaataatg ttactttaac agggggcgga gaaaatgtta ctaatgagtt
    10621 aaaggataaa tttactagcg gtgactttac tgtagtgatt aagtacaatc agtctagtga
    10681 gaaaggctta caagctctgt ttggaatatc taattctaaa cccggtcaac aaaatagtta
    10741 tgtagatgtg ttccttagag acaatggtga attgggaatg gaagcgcgtg atacttcttc
    10801 caataaaaat cacctagtat ccagacctgc ttcagtttgg ggtaagtaca aacaagaagc
    10861 tgtgactaac actgttgcag tagtagcaga ttcagtcaaa aaaacatatt ctttatatgc
    10921 aaatggtaca aaagtagtag aaaagaaagt ggataacttc ttaaacatca aggatattaa
    10981 aggtattgat tactatatgc ttgggggagt gaaacgtgca ggaaaaacgg cgtttggttt
    11041 taacggaaca ctagaaaata tcaaattctt taatagtgca ttggatgaag aaactgttaa
    11101 aaagatgaca acaaacgctg ttactggaca tttaatttat acggctaatg atacaacagg
    11161 ttctaactat ttccgtattc cagttctgta tacttttagc aatggtcggg tattttcaag
    11221 cattgacgct cgttacggcg gaactcatga ttttttgaat aaaattaata ttgctacaag
    11281 ttatagtgat gataatggta agacatggac taaaccaaaa ttaacattgg cattcgatga
    11341 ttttgcgcca gtaccattag aatggcctcg tgatgttggt ggacgtgact tacaaatcag
    11401 cggtggtgca acctatattg actctgttat tgttgaaaaa aataacaaac aagtactcat
    11461 gtttgcggat gtgatgcctg ctggagtaag ttttagagaa gctactagaa aagattcagg
    11521 ttataaacaa attgatggta attattacct taaattaaag aaacaaggtg atactgatta
    11581 caattatact attcgtgaga atggtactgt atacgacgat cgtaccaaca gaccaactga
    11641 attttcagta gataaaaatt tcggtattaa acaaaatggt aattatttga cagtagagca
    11701 atattcggtt tcatttaaaa ataataaaaa gactgaatat cgtaatggga ctcacgtcca
    11761 tatgaatatc ttctacaaag atgcattgtt caaagtagtg ccaacgaact atattgcata
    11821 tatttctagc aatgatcatg gcgaatcttg gtctgcacca actttattac ctcctataat
    11881 gggacttaat cggaatgcgc cttatttggg tcctggacgt ggaatcattg aaagctcaac
    11941 tggacgtatt cttattccgt cttacactgg taaagagtct gcattcattt atagtgacga
    12001 taatggagca tcttggaaag ttaaagttgt gccacttcct tctagttggt cagcagaagc
    12061 acaatttgta gaattgagtc caggagtaat tcaagcatac atgcgtacaa ataatggtaa
    12121 aattgcatat ttaacaagta cagacgcagg tactacttgg agtgcaccgg aatatttgaa
    12181 atttgtttca aatccaagtt atggaacaca attatcaatc atcaattata gtcaactgat
    12241 tgatggtaaa aaggctgtca ttttaagtac tccaaactcc acaaatggtc gtaaacacgg
    12301 acaaatttgg attggtctaa ttaatgatga taatacaatt gattggcgtt atcatcacga
    12361 cgttgattat agtaactatg gatactcata ttcaacattg acagagttac caaatcatga
    12421 aattggattg atgtttgaaa aatttgattc atggtctcgt aatgaacttc atatgaaaaa
    12481 tgttgtacca tatataacat ttaagattga agatctgaaa aagaattaaa gctgaaattt
    12541 gaaaatatat aaaaagagga taaaaattat ggtaaattac ggtattgttg gagctggata
    12601 ttttggagct gatttagctc gctcaatgaa caaaattgaa gatgcaaaag tggttgcggt
    12661 atttgaccca aatcatggag aagaagttgc tcaagagttg ggatcagatg tttgtgcaag
    12721 tttagatgaa cttgtagcac gtgaagatat tgattgtgtg atcgtagctt cacctagcta
    12781 ccttcaccgt gaaccagttg tgaaagctgc tcaacatggc aaacacgtat tttgtgaaaa
    12841 gccaattgca ttgtcttatg aagattgtaa agccatggtt gacgcatgta aagaaaataa
    12901 tgttatcttt atggctggtc acatcatgaa cttctttaac ggtgtacacc atgctaaaga
    12961 attgattact caaggtaaaa tcggtaaagt tctttattgc catgccgctc gtacaggttg
    13021 ggaagaacaa caaccaactg tatcatggaa gaaacttcgt tctcaatctg gaggacattt
    13081 gtaccatcat attcatgaat tagattgcat tcagtttatc atgggaggac ttcctgaaaa
    13141 agcgacaatg gtaggaggca atgtatatca taaaggtgaa aactttggtg atgaagatga
    13201 tatgctcatt gtaaacttag aatactctga tgatcgttat gctgttttgg aatatggtaa
    13261 tgctttccgt tggggtgaac actacgtctt gattcaagga actgaaggag ctatcaaact
    13321 tgatttgttc aatactggag gtactcttcg tgttaaaggt gaaggagaat cacacttctt
    13381 agttcatgaa actcaagagg aagatgatga ccgtacagct atctataccg gtcgtggtat
    13441 ggatggagca attgcgtacg gtaaaccagg agtacgttgc ccattatggt tgcaaacatg
    13501 tattgataaa gaaatggaat atctacatga catcattaaa ggtggagaaa ttacagaaga
    13561 atatgaaaaa cttctcaatg gtgtagctgc tttagaatca atcgctaccg ctgatgcatg
    13621 tactttatca gttaaagaag atcgaaaagt aagtctttca gaaatcacaa atgcttaact
    13681 tttgtaaaac agaatagtaa attcttatca ttatataatt tctaaagttc tgtgatacaa
    13741 ctcattgaat aaagaaatag agatgggact gggataatgc ccagtcccat tttttatcaa
    13801 aaagtaatga gatcaaaaat gtgggagtga tgaaatgaag attataggga tcgatattgg
    13861 cggaacaaca attaaagcag atttatacaa tgagtttgga acgagtttaa atcagttcaa
    13921 agagatagaa acaattattg actatgattt gggaacgaac cagatattaa atcaggtctg
    13981 tgatttaatt ggtgagtata ttttaaatca ttcaattgat ggtgttggga tttccactgc
    14041 tggagttgtt aatgctaata caggagagat catctataca ggctatacaa taccagggta
    14101 tatcggagta aactttactt tcgaaataga aaaacgtttt gggttgtcta cttttgttga
    14161 aaatgatgtt aattgtgctg cattaggtga attgtggaag ggacaagcca aagataagaa
    14221 aaatgtagta atggttacta ttggaacagg tataggaggc agtattattg tcaatggaca
    14281 aattgttaac ggatttaact atactgctgg tgaagtaggc tatattcctg taggtaattc
    14341 ggattggcaa agcaaagcct caacaaccgc attgattcat ttatatcaaa agaaaagctt
    14401 gaaaactaat caaactgggc gtactttctt tactgattta agagctggag ataaagtcgc
    14461 taaagaaact tttgaaattt ttgtagaaaa tctaacaaaa ggtttattaa cgattactta
    14521 tctacttaat ccagaaattc tcatattagg aggtgggatc ctggctaaaa aggatatttt
    14581 gttacctgaa attcaaagtt ctttagctaa aaatgcaatg gataataggt ttttgcctaa
    14641 aaatcttgtg gcagctacat taggaaatga agctggtcgt ataggagctg taaaaaattt
    14701 cttagataga atttctaata aatagtatga aagataagga ggtgtcacaa tgactaactc
    14761 tgtattttcg acaatgcaag atattgagaa tgttgcaacc gatattataa aatcatatga
    14821 taatgagatt tatacttata aagctgtttc ccaagaagaa ttggaaaaac tagaaaaaag
    14881 ttatgatgaa aaaagtcacg aagaattagt ttcaatagaa agcaatttag aaatgaaaca
    14941 acagaacctt attgatgagg ttaataaaac aatcaaggaa aattatgaaa agattcagta
    15001 tatttcatca agtaggagag gagaatttgt agaaaaaatt attggtaggg tggtagaaaa
    15061 atatggctat tagtcagatg aaaagaattt ctctactatt ttctaaaagt agtcttgatg
    15121 atgttttaaa aactattcaa gaactagagt cagtgcagtt ccgtgattta aaggttcagg
    15181 ataactggtc agaagctcta gaaaaagatg aggttgtatt tccaactatt caaatttctc
    15241 atacttctaa ttccaatcat ggggttattg aaggaaatga tgccttgatt tatttgatga
    15301 atcaacaaca atatttagaa gcaactgtag agaaattaca agaataccta ccgaaagaaa
    15361 acacgtttaa attattacag caacctccga taacgacctc ttatgaagaa ttagaaaaat
    15421 ttggtaaagc taatgttgct gagggtgttc ttaaaaaagt gaatcgtcaa ataaacagag
    15481 ttcatgaatt agaaagacac attcaaagta ataatgagga aatagagaga ttaataaaat
    15541 gggaaaaatt agaaattatt cctgcgcatt tagaacaatt ttttttctgt aaaggaaaag
    15601 tcggaacaat tccaaggact gtagataatc gcttatacaa tagtttttta gaaaacaata
    15661 ttgaagttca agaaatattt tctaatgata gagagtacgg tgttgttgtt ttctatcagt
    15721 ccagttgctc tattgatttt gatgaatact tatttgaacc atttgattat tctagaaagg
    15781 aattaccgaa gcagcgagta gtagatttgg atcaagaaaa catgcagtta ataactgaaa
    15841 aagagaatat tatcgcatcg ttgcaagatt caaagaataa tttgatagat ttacaatggc
    15901 aaattgacta tattttatct atctatgctc gtcaaatctc taagaataac cttttgagca
    15961 ctccgcatct agttgcacta gaaggatgga tagaagaaac tcgt
//
LOCUS       DAVBDR010000048        15230 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.048, whole genome shotgun sequence.
ACCESSION   DAVBDR010000048 DAVBDR010000000
VERSION     DAVBDR010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15230)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15230)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15230
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.048"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            219..1901
                     /locus_tag="VQ540_001587"
     CDS             219..1901
                     /locus_tag="VQ540_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2545364.1"
                     /translation="MKEAIIEWKDFSFRYETQQEPTLQGIDLTIYKGEKVLIVGPSGS
                     GKSTLGQCLNGIIPNIYKGQTYGEFLIKGQTAFDMSIYDKSHLVSTVLQDTDGQFIGL
                     SVAEDLAFALENDVTALDEMKGRVYKWAEKLDLLPLLDQRPQDLSGGQKQRVSLAGVL
                     IDESPILLFDEPLANLDPKSGQDIIELIDQIHKEEGTTTLIIEHRLEDVLHRPVDRIV
                     LINDGRILFNGSPDQLLATDLLTQNGIREPLYLTTLRQLGVDLVKEEQLANLDNMSIS
                     KGQVQLQNELVKETPELQSLFKLEDVSFSYDDRPILKSLHLDIKKGEKIAIVGKNGAG
                     KSTLAKAISSFIQTEGRYLWEKQDIKGDSVAERAERVGYVLQNPNQMISTNMIFDEVA
                     LGLRLRGVDEKEIETRVYETLKICGLYEFRNWPISALSFGQKKRVTIASILVLGAEII
                     LLDEPTAGQDQKNYTEIMEFLEELHRKGHTIVMITHDMQLMLDYSDRVLVMVDGELIA
                     DTVPASLLSDPELLVKANLKETSIFNLAKKLDVDPLDLTAFYKERREGCKLN"
     gene            1886..2716
                     /locus_tag="VQ540_001588"
     CDS             1886..2716
                     /locus_tag="VQ540_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HET2545365.1"
                     /translation="MQAKLIGYQHRDTVIHRLSGAGKLLFFILVSLAAMISYDTRMLL
                     LIAIFSVFLLYLSEIRFKDVSFVAVFATVFAVLNVLMVYLFSPEYGVGLYGERSVIWQ
                     GIGVYTLTSQELFYLLNLAIKYLCTIPLAIIFLMTTHPSQFASSLNQIGVPYKIAYSV
                     SLTLRYIPDLQEEFFTIKMSQEARGMELSKKASLMQRIKGNLLIITPLIFSSLERIDT
                     IATAMELRRFGKEKKRTWYSYQALKKGDYITLLLATLFLVASLLLSLQNQGRFYNPWK
                     "
     gene            2909..3412
                     /locus_tag="VQ540_001589"
     CDS             2909..3412
                     /locus_tag="VQ540_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (cytidine(34)-2'-O)-methyltransferase"
                     /protein_id="HET2545366.1"
                     /translation="MTNHIVLFEPQIPQNTGNIARTCAATNSPLHIIKPMGFPIDDRK
                     MKRAGLDYWDKLEIYFYESLEDFISQMKGKLYLISKFAEKVYSEVDLSTDEDHYFLFG
                     REDKGLPEDFMREHPEKALRIPMNDEHVRSLNVSNTVCMIVYEALRQQNFAGLELVHT
                     YEVDKLK"
     regulatory      3466..3700
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            3865..4428
                     /locus_tag="VQ540_001590"
     CDS             3865..4428
                     /locus_tag="VQ540_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HET2545367.1"
                     /translation="MTNTRRLSTIAILSAISFVLMYFDFPLLPAASFLKIEFSILPVL
                     VGLVVMDLPAALGVLLLRSLLKLLLNSQGVNTYIGLPMNIVALGVFVIVFALIWKKER
                     TTLRFLLGSLAGTIGLTVAMLVLNYVYAVPLYAKFANFDIGKILGLSNYLMTMVLPFN
                     LIEGVIFSVSFWLLYILLKPTLKHYER"
     gene            4442..5068
                     /locus_tag="VQ540_001591"
     CDS             4442..5068
                     /locus_tag="VQ540_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HET2545368.1"
                     /translation="MKGSFALLLFVILGYMVKFYPEMLVNFDQSIQTAIRGDLPDYLT
                     ILFRSLTRLIDIPVIITWVVIIAFVFYRKRWKIESFFMLGNLTLAGLLIVTFKNIYQR
                     PRPAILHLVEEKGFSFPSGHSLAVTLMVGTLIVILSQRIKDQVWRKIVQIVLGLYLVS
                     VLVSRVYLGVHYPSDVLASLCVGLGALFIEFPFYDKLRFQWRFKGKQK"
     gene            5180..6052
                     /locus_tag="VQ540_001592"
     CDS             5180..6052
                     /locus_tag="VQ540_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000525616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET2545369.1"
                     /translation="MGMLLATRLKNKRKELKLSQKELAEGICEQGQISRMEQGKYSPG
                     SELLFQLSKRLKVSMDYFFEDTEVSSLENIDKFKELSKKFLDEREYESLHYIYELEKS
                     KRARLSAKDQIYLDWIDTLVQFCYLNHQTGAVAKLEKILLSLKKSDFYYLQLGNTLAN
                     FYFDMGQEDTYQELYQLLKENLQSLSVHHLEQLELMIKFRYNYCRYLWLNERTSEAIE
                     EITETIAICKRYNSSYRLADLYCLLGSISEGFAERDRILGFYQVSYQLYKHEENQRMM
                     LEIEKEMKLLESED"
     gene            6182..6319
                     /locus_tag="VQ540_001593"
     CDS             6182..6319
                     /locus_tag="VQ540_001593"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2545370.1"
                     /translation="MKRSQVVKRCILIALLLLFLLNVLSGSLSVTTRGVDPRPAYGVS
                     L"
     gene            6743..7657
                     /locus_tag="VQ540_001594"
     CDS             6743..7657
                     /locus_tag="VQ540_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000781144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ThiF family adenylyltransferase"
                     /protein_id="HET2545371.1"
                     /translation="MKLYQINDGIQIFESSNLEKIVIRNYRNGKKITIDHQPLLKKLL
                     LFLEVPKREEEILLYLPELSNKTLRSVLTNFMSLNIIHCQDTLIIHKKINILIIGLGT
                     TGGYLADGLCRSNINSKLFLLDKDRVDETNVGRQIYLRDDIGQYKVDVFKQKFSDKEI
                     KVFKIFINSKKDLEKICKREGIDLVIQCGDSPSPRELGKIVNTVCDTLQIPYIVNTGY
                     MSNVVPLPEFYYPNNRYNFNYKHQFSDEKLLFSQVLSKADYMVAIQSSFVMLMQIKNF
                     IFNEEPIYYGYRGYYNSVTLAWEVEKID"
     gene            7650..8663
                     /locus_tag="VQ540_001595"
     CDS             7650..8663
                     /locus_tag="VQ540_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2545372.1"
                     /translation="MTKYLELDYSHSYILEGFRKNDAFIENHKECLDMLSDKIWRDNK
                     YMNTEKNISSPTRTILSRYTCNILSSLFIDISKNSIEKLIVTCENSDLNWIYNYYKSV
                     YNGVFCELRQLIQQYCKVKDKYEKWLFIKAIINQGIRQNEKEVVEFFLKQLKDNNQGI
                     FDYINSFSFYLLKFYSKDKSRIFLEEQLDIDDFLGSDKEDYARSLVFKNYASLLPDTS
                     ELKRNIMEKCLSQTPQDTDLWKEWFETYASQKEIRQKATEIFKHGYSDISLLKLVKIE
                     PDDTESLIRMIILCTSDLNSNIARYLISFLSDGRLKEFLELFVENFDFLNIIEGKTSE
                     INF"
     gene            8647..10239
                     /locus_tag="VQ540_001596"
     CDS             8647..10239
                     /locus_tag="VQ540_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001236730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2545373.1"
                     /translation="MRLIFRIIRKDIILYSILTFLLSIAMVSEAFLMQFIVDSIKFGE
                     KKYVLISIFIVIFLILQTLLYYYQQFLTAVLSKKSAYEYRKLIFKNIQQTSLRLVTGE
                     KNDSILASLTTQIDQIEYNYFYSVYWGGYLLCQLVVAIVMSLYLNPLMSVLTICLSLP
                     NLFVALLFKNSLEQKQEELINETNSSIAVTQDLIEGITDWKIANREPNIFRVFESKTL
                     KLLEKQVKVEKFQYIVVSLNQLFSNVLYFGSWIVGGFLIIRGQLSLGSLIAFSQLLAR
                     ISYPVYASSDLLSKYISGKKIVEILSKEFIFSDESRNYPDEFNVISFEHYFTNIDEKD
                     MPFDKEFYKNKKYLLKGKSGSGKTTILKSILREYDDYSGIVKINGVDVRDIKESVLFD
                     NIAYVSQKPHLFSASLRDNLTLFSEDFTDNEIVEVLKFVELSKWANKDCLDMMLSNDD
                     IKLSGGEVKRVSLARALLMNKNILLLDEFSAGIDYETLLKIEKKLIDLDKMIIYVTHV
                     DIDRSGKQFDDVIDLDCLFISS"
     gene            10431..11334
                     /locus_tag="VQ540_001597"
                     /pseudo
     CDS             10431..11334
                     /locus_tag="VQ540_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001091364.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
     gene            11352..11489
                     /locus_tag="VQ540_001598"
                     /pseudo
     CDS             11352..11489
                     /locus_tag="VQ540_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853067.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
     gene            11517..11858
                     /locus_tag="VQ540_001599"
     CDS             11517..11858
                     /locus_tag="VQ540_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2545374.1"
                     /translation="MKVNIADLHPTQLYLSEKKLQDIQMLYQSAETIQVDPISILAFG
                     DCLLITDGHHRAYQALLAGRDTISAEWDRDGGDELYHLYAQACEERKIYSVFDLKNHI
                     LPLWIGMVSFF"
     gene            11831..12142
                     /locus_tag="VQ540_001600"
                     /pseudo
     CDS             11831..12142
                     /locus_tag="VQ540_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333655.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            12270..12857
                     /locus_tag="VQ540_001601"
     CDS             12270..12857
                     /locus_tag="VQ540_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HET2545375.1"
                     /translation="MELEVFAGQEKSELSMIEVARAILELRGRDHEMHFSDLVNEIQN
                     YLGTSNSDIREALPLFYTELNFDGSFISLGDNKWGLRSWYGVDEIDEEIIALEENDDD
                     EVAPKAKKKRVNAFMDGDSDAIDYNADDPEDEDAYEADPALSYDDENPDDEKNEVEAY
                     DAEINEIAPDDLGEDVDLNEDDDEFSDDDAETSEE"
     gene            13247..14854
                     /locus_tag="VQ540_001602"
     CDS             13247..14854
                     /locus_tag="VQ540_001602"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HET2545376.1"
                     /translation="MSTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPY
                     INIDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRK
                     ERRGEYLGATVQVIPHITDALKEKIKRAALTTDSDVIITEVGGTVGDIESLPFLEALR
                     QMKADVGADNVMYIHTTLLPYLKAAGEMKTKPTQHSVKELRGLGIQPNMLVIRTEEPA
                     GQGIKNKLAQFCDVAPEAVIESLDVEHLYQIPLNLQAQGMDQIVCDHLKLDAPAADMT
                     EWSAMVDKVMNLKKQVKISLVGKYVELQDAYISVVEALKHSGYVNDVEVKINWVNAND
                     VTAENVAELLSDADGIIVPGGFGQRGTEGKIQAIRYARENDVPMLGVCLGMQLTCIEF
                     ARHVLGLEGANSAELAPETKYPIIDIMRDQIDIEDMGGTLRLGLYPSKLKRGSKAAAA
                     YHNQEVVQRRHRHRYEFNNAFREQFEAAGFVFSGVSPDNRLVEIVEIPENKFFVACQY
                     HPELSSRPNRPEELYTAFVTAAVENSN"
BASE COUNT         4719 a         2373 c         3209 g         4929 t
ORIGIN      
        1 tacggcaagg cgaaactgac gtggtttgaa gagattttcg aagagtataa aatgatgggg
       61 aaggctgggc aactagtctt tttcgatgtt tatagattag ttaggcaagt aagctaggat
      121 aggaatcttt ttggtgctaa gattttaaga gaagagactg caagaagggc ttgatttatg
      181 ataaaataga agtctaagaa gcgaatgaag agagtaagat gaaagaagct ataattgagt
      241 ggaaggattt ctctttccgg tatgaaacac aacaagaacc gaccttgcaa gggatagact
      301 tgaccattta caagggagag aaagtcttaa ttgttggacc atctggatca ggtaaatcta
      361 ccttgggtca gtgtttgaat gggattattc ccaatattta caagggtcag acatatggag
      421 aatttttgat aaagggtcaa acagcctttg atatgagcat ctatgataag tctcatctgg
      481 ttagcacagt tttgcaggat acagatgggc agtttattgg cttgtctgtg gcagaagatt
      541 tggcgtttgc tctggaaaat gatgtgacag ccctagatga gatgaaaggt cgtgtttata
      601 aatgggctga aaagctggac cttcttcctt tactggatca gcgtcctcag gatttgtcag
      661 gtggacaaaa gcagcgagtc agtctggctg gtgtcttgat tgatgaaagt ccgattctct
      721 tgtttgatga gccactcgcc aatctagatc ccaagtcagg tcaggatatt atcgaattga
      781 ttgaccagat tcataaggaa gaggggacga cgactcttat tatcgagcac cgtttggagg
      841 atgttctgca tcgccctgtg gatcggattg tcttgataaa cgatggtcgt atccttttta
      901 atgggagccc tgaccagttg cttgcgactg atttattgac tcaaaatgga attcgagaac
      961 ccctttatct aaccactctc cgtcaattag gtgtggactt agtcaaggaa gaacagttag
     1021 cgaatctgga taacatgtct atctcaaaag gtcaggttca gctgcagaat gaactggtaa
     1081 aagaaactcc agaattgcag tcactcttta aattagagga cgtgtctttc tcttatgatg
     1141 atagaccgat tttaaaatcc ctacatttag atattaaaaa gggtgaaaag attgctattg
     1201 tcggaaaaaa tggagcaggg aaatcaactc tagccaaggc tataagtagc tttattcaga
     1261 cggaaggacg ctatctttgg gaaaaacagg atataaaagg cgattctgtt gcagagcggg
     1321 cggaacgagt aggctatgtg ctacaaaatc ctaatcaaat gatttcaacc aatatgattt
     1381 ttgatgaggt ggctctaggg ctccgtttgc gaggtgtgga tgagaaggaa attgaaacga
     1441 gagtctatga aaccttgaaa atctgtggac tttatgaatt ccgtaattgg cctatttctg
     1501 ccctgtcatt tggtcagaaa aaacgtgtca ccattgcttc aattttggtc ttaggagctg
     1561 aaattattct cctagatgaa ccgactgcag gtcaagatca gaagaactat actgagatta
     1621 tggaatttct cgaagagtta catcgaaaag ggcataccat tgtcatgatt acccatgata
     1681 tgcaattgat gctggattat tcagaccgag tccttgtcat ggtggatgga gaattgattg
     1741 ccgatactgt tccagccagt ctgttgagcg atcctgagct gttagtaaaa gccaatctaa
     1801 aagaaacctc catctttaac ttggctaaga aactagatgt ggatccactg gatttaacgg
     1861 cattttacaa agaaaggaga gagggatgca agctaaatta atcggttacc agcatagaga
     1921 tactgtgatt catcgcttgt caggagctgg gaaacttctc tttttcattc tggtatcatt
     1981 ggcggccatg attagctatg ataccagaat gctcttgctg attgccatct tttcagtctt
     2041 tctcctctat ttatcagaaa ttcgctttaa agatgtttcc tttgtagccg tttttgcgac
     2101 ggtatttgcc gttttaaacg ttttgatggt ctatctcttt tctcccgagt atggggttgg
     2161 actttatgga gagagaagtg tgatttggca gggaatcggt gtctacactc taaccagcca
     2221 ggagctcttt tatctgctaa atttggccat taagtatctt tgcaccattc ctctggctat
     2281 tatctttttg atgacaaccc atcctagtca gtttgcttcc agtttaaatc aaattggtgt
     2341 gccctataag attgcttatt ctgtcagcct gaccttgcgc tatattccag atttgcagga
     2401 agaattcttt actatcaaga tgtctcagga ggcgcgtggg atggaattat ccaagaaagc
     2461 ttctcttatg caacgaatca aaggcaatct gctcattatt acgcccttga tttttagctc
     2521 gctagaacgc attgatacca ttgcgactgc catggagctt cgccgctttg ggaaagaaaa
     2581 aaaacgcaca tggtatagtt atcaggcctt gaaaaaagga gactatatta ccttgctctt
     2641 ggcaaccttg tttttagtag ctagtttact acttagcttg cagaatcagg gacgatttta
     2701 caacccttgg aaatagcttg aaaaaattga aaaaatcaag tcgtttctat tgacaatgat
     2761 tctgaaagtg ttatactaag aaagtagttt cgctgattta cttcaaacct gttgtgaggt
     2821 aagttaacga tgccttaacc acgctgtttg ctgagcttga ctccgggcag tgtggctatt
     2881 tttttgcaat ggtgaaagga agcaagtcat gacaaatcac attgtattat ttgaacctca
     2941 aattccacaa aatacgggca atatcgcgcg tacttgcgct gcgaccaatt ctcccctcca
     3001 catcatcaag cctatgggct ttcctattga tgaccgcaag atgaagcggg ctggattgga
     3061 ttactgggat aagctagaga tttattttta cgagagtttg gaagatttca tatctcagat
     3121 gaagggaaaa ctctatctga tttcgaaatt cgcggaaaaa gtctattctg aggtggattt
     3181 atcgactgac gaggaccatt attttctctt tggacgtgaa gacaagggct tacctgaaga
     3241 ttttatgcga gaacatcctg agaaggctct ccgtattccc atgaatgatg aacatgtccg
     3301 cagtctcaat gtgtctaata ccgtctgcat gattgtctat gaggctcttc gccagcagaa
     3361 ctttgcaggt cttgaactcg tccataccta tgaagtggat aaattgaaat aaaaaatgaa
     3421 aatgaacaaa atgcttgcgc ttgcaagcgt tttttgttat gataaaagag tcttcagggc
     3481 agggtgtgat tcccgaccgg cggtgacttt aactaggaaa tgatcttttc cttttatact
     3541 ttgttgacaa gctttgccta accagaagtt atgcctacag cttgtcgcct agtctaaaag
     3601 aaaaatctct atttccttct ctttaaagaa gtccgcgagc gcaagctgat gtggtgagat
     3661 tccacaaccg acagtatagt ctggatggga gaagacgaaa gaatagcttt gtctgttttg
     3721 atagatttat agccggattg taaccacttg ctttgttttt ctttaataga gtaggaggga
     3781 acttttggga tataaaaagt gagaatagat agaggaatcc tttccaactt cttctgattt
     3841 tatagaaaat tggaggaacc tgttatgaca aacacacgtc gactttcgac cattgcaatt
     3901 ttatcagcca tctcatttgt gctgatgtac tttgactttc cgcttttacc agcggcatct
     3961 ttcctcaaga tcgaatttag tatcttgcca gtccttgtgg gtctggtggt catggatttg
     4021 cctgctgctc taggagtgct cttgcttcgc tcactcttga aattgcttct taacagccaa
     4081 ggagtgaata cttacattgg tttgccgatg aatatcgtag ctttgggagt ttttgtcatc
     4141 gtatttgctt tgatttggaa aaaggaacgg acaacccttc gtttcctact aggctctcta
     4201 gctgggacta ttggtttaac cgtggctatg ttagttctca actatgttta tgctgttcct
     4261 ttgtacgcta agtttgctaa ctttgatatt ggaaaaattt tgggactttc caactaccta
     4321 atgaccatgg tattaccttt taacttgatt gaaggtgtaa tcttttccgt ttcattctgg
     4381 ttgttgtaca ttctcttgaa accaacctta aaacattatg aaagataaac aaacattttt
     4441 aatgaagggc agttttgccc ttttactttt cgttattctt ggctatatgg tcaaatttta
     4501 ccctgaaatg ttggtcaatt ttgaccaatc gattcagact gccattcgag gagacttacc
     4561 agattatttg actattcttt ttcgatccct cacacgtctg attgatattc cagtgattat
     4621 cacttgggtt gtcattatag cttttgtctt ttatcgtaag cgatggaaga tagaaagttt
     4681 cttcatgctg ggaaatctga ctttggcagg tcttttaatc gtgaccttta aaaatatcta
     4741 ccagcgccca cgaccagcta tcttacatct ggtggaggag aagggatttt ccttcccaag
     4801 tgggcattct ctggctgtaa cgctgatggt agggactttg attgttattc ttagtcagcg
     4861 gattaaagat caggtctgga gaaaaatcgt acaaatcgtc cttggcctct acctagtcag
     4921 tgtgctggta tcaagagtct atctgggagt tcattaccca tcagatgttc ttgccagtct
     4981 ctgtgtgggc ttgggagccc tgtttatcga gtttcccttt tatgataagc tccgcttcca
     5041 atggcgattt aaaggcaaac agaaatgatg gaaaagataa aaaattgtac aaatacaaat
     5101 agaaccatat gaaatatata cttgaaacat gttttggagt ttgatatatt ttaataaata
     5161 aagcaaggag gaagaaagtg tgggtatgtt attagcgaca cgcttaaaaa ataaaagaaa
     5221 ggaattaaaa ttatctcaaa aagaattagc tgaggggatt tgtgagcaag ggcagattag
     5281 ccgtatggag caaggtaaat actcacctgg gtcagaatta ctctttcaac tatctaagcg
     5341 attgaaggtg agcatggatt atttctttga agatactgag gtttctagtt tagaaaatat
     5401 tgataagttt aaagaattat ctaagaaatt tttggatgag agggaatatg aatctctcca
     5461 ttacatctat gaactggaaa aatctaaacg tgctcgtcta tctgctaaag accagattta
     5521 tttggattgg attgatacat tagttcaatt ctgttattta aatcatcaaa caggggcagt
     5581 tgcgaaactg gaaaaaatac tgttatctct gaaaaaatct gatttttact atctacaact
     5641 gggaaatacc ttggctaatt tttattttga tatggggcag gaagacacat atcaggaact
     5701 ctatcaactt ttaaaagaga acctccagtc actatctgtt catcatttgg aacagttaga
     5761 attgatgatt aaattccgat ataactattg tagatatttg tggttgaatg aacgaacatc
     5821 tgaagctata gaagaaatta cagaaacgat agctatttgt aaaagatata atagtagtta
     5881 tcgattagca gatttgtatt gtttattggg aagtataagc gagggctttg ctgaaaggga
     5941 taggatacta ggtttttatc aagtatctta ccagctttac aagcacgaag agaaccagag
     6001 aatgatgcta gaaattgaga aggaaatgaa attattggaa agtgaagatt aagcaaaaag
     6061 atttgtattc ttagataact ttaatacata ttataaaaaa aataaaaaaa tatcataaaa
     6121 attattgaca aaccaaaatt gatgtgttag aatatcacca atagttaagg aggtttagaa
     6181 gatgaaaaga tctcaagttg tcaaacgatg tatattaatt gctttattgc ttctatttct
     6241 acttaatgtg ttaagtggtt ctttatctgt aacaactaga ggagttgatc caagaccagc
     6301 atatggagtt tcgctttaaa gttgtgcata gttcttcttt tatagacgga gagtttttct
     6361 caatagtaag tgattcaaat tttgatggat gattttccat taaattaagt gattgcgaaa
     6421 actttttgaa atacattctc tttggatatt gaaagtttgt tttggatttt tttatgaagc
     6481 ttatcttagc tgttagattg gggttttatg ggatttgtcc tcaccgggaa aaaatcttaa
     6541 atctttgaag aaagaggttt ttatcttatg gttagagata catcagaaga aattgaagtt
     6601 attgacttgt cttctatgac cgtttcctac tcatctgtta tgctaggaaa ctcttggatg
     6661 acgtggaatt gatttattaa gatagattat ttggttttta ccaaaaatct gtctttttaa
     6721 tttttaaagg actaatggtg atatgaaact atatcaaata aatgatggga tacaaatttt
     6781 tgaaagtagt aatcttgaaa aaatagtaat tagaaattat aggaatggta agaaaataac
     6841 tatcgatcac caaccattat taaaaaaatt actactattc cttgaagttc ctaaacgtga
     6901 agaagaaatt ctattatatc ttccagaatt atcaaataaa acattacgaa gtgttttgac
     6961 gaattttatg agtttaaata taattcattg tcaagataca ttaataattc acaaaaaaat
     7021 aaacatattg ataataggtt tagggactac gggtggatat ctggcagatg ggttatgtcg
     7081 tagtaatatt aattcgaagc tatttctttt agataaggat cgtgtagatg agactaatgt
     7141 aggtagacag atttatttaa gagatgatat tggtcaatat aaagttgatg tatttaaaca
     7201 aaagtttagt gataaagaaa taaaggtatt caaaattttt attaatagta agaaagattt
     7261 ggaaaagatt tgcaaaaggg agggtatcga tttggttata caatgtggtg actccccttc
     7321 acctcgagaa ttaggaaaaa ttgtgaatac agtatgtgat actctccaga taccttatat
     7381 agttaacact ggctacatga gtaatgtagt tcctttgcca gaattttatt atccaaataa
     7441 tagatacaat tttaattata agcatcaatt ttcagatgaa aagttactgt tctcacaagt
     7501 tttgtctaaa gctgattata tggtggcaat tcaatcatca tttgtaatgt taatgcaaat
     7561 aaaaaatttt atatttaatg aagaacctat ttattatggt tataggggat actataattc
     7621 tgtaacatta gcatgggagg tggaaaaaat tgactaaata tttagaattg gattattctc
     7681 attcatatat tttggaaggt tttagaaaaa atgatgcgtt tattgaaaat cacaaagaat
     7741 gccttgatat gttatcagat aagatttggc gagataataa atatatgaat acagaaaaaa
     7801 acatatcatc accgacacga acaatcttat cacgctatac ttgtaatatt ttatcgtctt
     7861 tgtttattga tattagcaaa aatagcatag aaaaattgat agtgacatgt gaaaatagcg
     7921 atcttaattg gatttataat tattataaat cggtttacaa tggagtattt tgtgaattgc
     7981 gacaacttat acaacagtac tgtaaggtga aggataagta tgaaaagtgg ctttttataa
     8041 aagctattat aaatcaaggt attcgtcaaa atgagaaaga agttgttgaa ttctttttaa
     8101 aacaattgaa ggataataat caaggtattt ttgattacat caatagtttt agtttttatc
     8161 tattaaagtt ttattcaaaa gacaaatctc gcattttttt agaagagcag ctagatatag
     8221 atgatttttt gggatcagat aaagaagatt atgctaggtc tttagttttt aagaattatg
     8281 cttctctatt gcctgatact tctgaattaa aaagaaatat tatggaaaaa tgtttaagtc
     8341 aaacacctca agatacagat ttatggaaag aatggtttga aacttatgcc agtcagaaag
     8401 agattagaca aaaagcaacg gaaatattta agcatggtta ttcagatatt tcgttactaa
     8461 aattagttaa aattgagcct gatgacactg agagtttaat cagaatgatt atcttatgta
     8521 ccagtgacct aaatagtaat attgcaaggt atttgatttc atttttgagc gatgggcgat
     8581 taaaagaatt tttggagtta tttgttgaaa attttgactt tttgaatatt attgagggaa
     8641 aaactagtga gattaatttt tagaataatt agaaaagata ttatattata ttctatatta
     8701 acatttttgc tatcaatagc gatggtaagc gaagcatttt tgatgcaatt tattgttgat
     8761 tcaattaaat ttggtgaaaa gaagtatgtt ttgatttcta tttttattgt aatttttttg
     8821 attcttcaga ctttattgta ttactatcaa caatttctta cagctgtatt aagtaaaaaa
     8881 tctgcatatg agtaccgtaa attaattttt aaaaatattc agcagacttc tcttaggctt
     8941 gttacaggtg aaaaaaatga tagtattcta gcttctttga caacgcaaat cgatcaaata
     9001 gaatataatt atttttattc tgtttattgg ggtggatatt tgctttgcca attagtggta
     9061 gctatagtta tgtcgcttta tctaaatcca ttgatgtctg tattaaccat ttgcttaagt
     9121 ctccctaatt tatttgtagc acttcttttt aaaaactcct tggaacaaaa gcaagaagag
     9181 ctaattaatg agacaaattc ctcaatagca gttactcaag atttaattga gggaattact
     9241 gattggaaaa ttgcaaatag agaacctaat atatttagag tgtttgaaag caaaacattg
     9301 aagcttttag agaagcaagt gaaggtagaa aaatttcaat acattgttgt tagtttaaat
     9361 caattgtttt caaatgtttt atattttggt agttggatag taggtggatt cttgattata
     9421 cgggggcaac tttcattagg gagtttgata gcgttctctc aattattagc aagaatttct
     9481 taccctgttt acgcttcttc ggatttattg tcaaaatata ttagcggtaa aaaaattgta
     9541 gaaattcttt ctaaagaatt tatattttca gacgaaagca gaaattatcc agatgagttt
     9601 aatgttattt catttgaaca ttattttaca aacattgacg aaaaggatat gccttttgat
     9661 aaagaatttt acaaaaataa aaaatatttg ttgaaaggga aaagtggtag tgggaaaaca
     9721 acaattttaa aatcgatttt acgagagtat gatgattata gtggaattgt aaaaattaat
     9781 ggggtagatg ttagggatat aaaagagagt gttctttttg acaatatagc ttatgtttcc
     9841 caaaaacctc acttgttcag cgcaagtctt agagacaacc tgacattatt ttctgaagac
     9901 ttcactgata atgagatagt tgaggtttta aaatttgttg aattatctaa atgggctaat
     9961 aaagattgct tggatatgat gctttcaaat gatgatataa aattatcagg aggggaggtc
    10021 aaaagggttt ctttagctcg agccttattg atgaataaga atattctgtt attggatgag
    10081 ttctctgctg ggattgatta tgaaacattg ttaaaaatag agaagaaact cattgatttg
    10141 gataagatga ttatttacgt gacgcatgtg gatatagata gatccggcaa acagtttgat
    10201 gatgtcattg atttggattg tctttttata tcctcgtgac atgagagttg agtcagttga
    10261 attattttgt cactctgttt agttcttgtt ggtagtgtca ggtaatcttt gttaattttt
    10321 caggaagtct attgaaatat cctcttggtt atatattacg aggagtaatt aatggatatt
    10381 ctcgagaatt caatacaaca atttgattct aaagttaagt atgtttcttt atttgcggaa
    10441 tcaatctttt atcagatacc atgagctatt ttgcaggtgc tatgatttct cctttgtatg
    10501 tgaggattat cggagatgat atgacagatg ctatgggggt tagacaggca actgctggtg
    10561 tagttaatat tctcagcaac cttatagggg gagttttgat tgggggtcat cagtcttcag
    10621 atgtttgtag gtttgaatgc tttgaccttt ctttttgcac tgttgggtgt ggtgtttatt
    10681 cgtacttctt tgagagatat tgaggaacag atggaggtta gtaaaagatt agccgcaaaa
    10741 tcttttggag agcatttcct ccattcaatg aagatattgt caagttttcc agccatcatc
    10801 aaattaatat tcattgcagc tatgaaccaa gtgattttaa gcattattat ccctttaacg
    10861 actttgatgt taatccatca tccatttatc ttctttgaca ctgggaaatc cattgcagca
    10921 ttgtcagtgg ttattttttc aggaacgatt gtgggaagtt ttttgagtgg aggtatccta
    10981 aaaaatattc ccataaaaat gattgtctac tttgaagaaa ttatgcatct ctgtattctc
    11041 ttttcttggt tgaccaatca tttcctcctt ttattggtag ttgtcttctt atgcgcagtt
    11101 gcagtaggaa tgatggggcc tcggattttc aaccttgtat tctcgatggt tccagaagaa
    11161 gtcatgggaa ccatccagtc agtgcttgga gtattcaatg ttgttgtacc aggaattctt
    11221 agcatgctca tcgttgcctt agcgagtgct acaaacctaa aaatcacagt gcttccactt
    11281 tttatttttg tattgactgc cttagcaatt gtgaaagcaa tgaaaataga gtaatagtag
    11341 tatgaactac tgtctctttt tgggtgggag ttcattaccc atcagacgtc cttgccagtc
    11401 tctgtgtggg cttgggagtt ttgtttatcg agtttccctt ctatgacaag ctccgcttcc
    11461 aatggcgatt taaaggcaaa cagaagtgag tatcgaattc ccttgaggag aaagaaatga
    11521 aagtcaatat agcagatctt catccgactc aactatattt atcagaaaag aagttgcaag
    11581 atattcagat gctttaccag tcggcagaaa caatccaagt cgatccaatc agtattcttg
    11641 cctttggaga ttgtttgctg attacagatg ggcatcacag ggcttatcag gctttattgg
    11701 caggtcggga tacgatttct gctgagtggg atagagatgg tggtgatgaa ctatatcatc
    11761 tctatgcgca agcttgcgag gaaagaaaga tttactctgt ttttgattta aaaaatcata
    11821 tcttacctct ttggatcggc atggtgagct ttttttgatt gaagtcaagg agaagggaga
    11881 atggtttcca attggggata ttacactatc tcaggataat ctccccattg tgattgggaa
    11941 ttccgcttac caacatcgag gacttggaaa aaagattcta agtgctttga ttgaattggc
    12001 tcgagtaaaa ggatggaaag aattgagagt caaggaaatc tacacctaca atcatgcttc
    12061 taggaggtgt ttcaagtcgc ttggatttgt ggaaaatgga gcaacagaaa aaggaaggag
    12121 ttttatattg gaattagtct aatcctgcca ctttctcccc cttaaccttt gactattccg
    12181 caaaattatc gtaaaataaa gagtaaatga taaaatgagg tcagagtctg ttcgctctga
    12241 cgatagtagt ataaatgagg agaaacgctt tggaattaga agtatttgct gggcaagaaa
    12301 aaagtgaact atctatgatt gaggtagcgc gtgctatatt agaacttcgt ggtcgcgatc
    12361 atgagatgca ttttagcgat cttgtaaacg aaattcaaaa ctaccttgga acatcaaaca
    12421 gcgatatccg cgaagctttg cctctgttct acacagagtt gaactttgac ggtagcttca
    12481 tctcacttgg ggacaacaaa tggggtcttc gttcatggta tggtgtggac gaaatcgacg
    12541 aagaaatcat cgctcttgaa gaaaatgacg acgatgaagt agcaccaaaa gctaagaaaa
    12601 aacgtgtcaa tgcctttatg gatggtgatt cagatgccat tgactacaat gcagatgatc
    12661 cagaagacga agatgcatac gaagcagatc cagctctttc atacgatgat gaaaatccag
    12721 atgatgaaaa aaatgaagtg gaagcttatg atgcagaaat caacgaaatc gctccagatg
    12781 acttgggaga agatgtggat ctcaacgaag acgacgacga gttttcagat gacgacgctg
    12841 aaaccagcga ggaataagag ttagctattg acaattatcc tatttttagg tatcatattg
    12901 tttgggcacc tcttttagag gtcggggctc cctagttctt agggagctat ttttgttttt
    12961 tcaagaagtt atcttcttgt attttatact caatgaaaat caaagagcaa gctaggaaac
    13021 tggccgtagg ctgctcaaaa cactgttttg aggttgtaga taagactgac aaagtcagga
    13081 acacatatct acggcaaggc gacgttgacg cggtttgaag agattttcga agagtattag
    13141 ttgtgaatct ggtgcagtcg tcccagatta ttcttattag tagggtcttg ttttctatat
    13201 cccctcgtag ttaacaagac cttgagcatt ttagaaagag gaatctatgt ctacgaaata
    13261 tatttttgta actggtggtg tggtatcgtc tattgggaaa gggattgtgg cagcgagtct
    13321 aggccgtctc ttgaaaaatc gtggtctcaa agtaaccatt caaaagtttg acccttatat
    13381 caatattgat ccgggaacca tgagtcctta ccagcacggg gaagtttttg tgacagatga
    13441 cggagctgag acagatttgg acttgggtca ctatgaacgt ttcatcgata tcaatctcaa
    13501 caaatattcc aacgtgacaa ctgggaaaat ttacagtgaa gttcttcgta aagaacgccg
    13561 tggagaatac cttggggcaa ctgttcaagt cattcctcat atcacagatg ctttgaaaga
    13621 aaaaatcaag cgtgccgctc taacgaccga ctctgatgtc attatcacag aggttggtgg
    13681 aacagtagga gatatcgagt ccttgccatt cctagaggct cttcgtcaga tgaaggcaga
    13741 tgtgggtgcg gataatgtca tgtatatcca tacaaccttg cttccttacc tcaaggctgc
    13801 tggtgaaatg aaaaccaaac caacccaaca ctctgtcaaa gaattgcgtg gcttgggaat
    13861 ccaaccaaat atgttggtta ttcgtacaga agagccagct ggtcaaggaa ttaaaaataa
    13921 actggcccag ttctgtgatg tggcaccaga agccgttatc gaatcgttgg atgttgaaca
    13981 cctttaccaa attccactga acttgcaggc acaagggatg gaccaaattg tttgtgatca
    14041 tttgaaatta gacgcaccag cagcggatat gacagaatgg tcagccatgg tggacaaggt
    14101 catgaacctc aagaaacaag ttaagatttc ccttgttggt aagtatgtgg agttgcaaga
    14161 tgcctatatc tcagtggtcg aagccttgaa acactctggc tatgtcaatg atgtagaagt
    14221 taaaatcaat tgggtcaatg ccaatgatgt gacagcagag aatgtagcag aactcttgtc
    14281 tgatgcggac gggatcatcg taccaggtgg ttttggtcaa cgtggtacag aagggaaaat
    14341 ccaagccatc cgctatgcgc gtgaaaatga tgttccaatg ttgggagtct gcttgggaat
    14401 gcagttgaca tgtatcgagt ttgctcgtca cgttttaggt cttgaaggtg ccaattctgc
    14461 agagcttgca ccagaaacaa aataccctat cattgatatc atgcgtgatc agattgatat
    14521 tgaggatatg ggtggaaccc ttcgtttggg actttatccg tctaagttga aacgtggctc
    14581 taaggctgct gctgcttatc acaatcaaga agtggtgcaa cgccgtcacc gtcaccgtta
    14641 tgagtttaat aatgccttcc gtgagcagtt tgaggcagca ggttttgtct tttcaggagt
    14701 ttctccagac aatcgtttgg tagaaatcgt ggaaattcct gaaaataaat tctttgtagc
    14761 ttgtcagtat caccctgaac tgtcaagccg tccaaaccga ccagaagaac tctacactgc
    14821 ctttgttact gcagcggttg agaacagcaa ttagcaaaat cagaaccttt gagaaaaatc
    14881 tcagaggttt tttgcatacg atgatattgc aatatatctg aggtaggggg cctctgtatg
    14941 tacctgctac cgttgaaatc aatagcgact ccctcttgcc ctgtgctagt gaatggattt
    15001 atcagtatat tgaaatgaaa taaaatttga acaaattaat tcggaaagcc aaatcaattt
    15061 ctagcaaagt tttaggaact ggattgtata gtgaattgaa ataagatgtg aacatctcta
    15121 tcagaaaagt caaattaatt tatagaaata ttttagcagt caagatgtac tgttatagat
    15181 tcaatacatt atactttttt aatttaatcc actatagtaa aatgaaataa
//
LOCUS       DAVBDR010000049        15083 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.049, whole genome shotgun sequence.
ACCESSION   DAVBDR010000049 DAVBDR010000000
VERSION     DAVBDR010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15083)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15083)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15083
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.049"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            16..1965
                     /gene="mutL"
                     /locus_tag="VQ540_001603"
     CDS             16..1965
                     /gene="mutL"
                     /locus_tag="VQ540_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HET2545377.1"
                     /translation="MSHIIELPEMLANQIAAGEVIERPASVVKELVENAIDAGSSQII
                     IEIEEAGLKKIQITDNGYGIAHDEVELALRRHATSKIKNQADLFRIRTLGFRGEALPS
                     IASVSVLTLLTAVDGASHGTKLVARGGEVEEVIPATSPVGTKVCVEDLFFNTPARLKY
                     MKSQQAELSHIIDIVNRLGLAHPEISFSLISDGKEMTRTAGTGQLRQAIAGIYGLVSA
                     KKMIEIENSDLDFEISGFVSLPELTRANRNYISLFINGRYIKNFLLNRAILDGFGSKL
                     MVGRFPLAVIHIHIDPYLADVNVHPTKQEVRISKEKELMTLVSEAIANSLKEQTLIPD
                     ALENLAKSTVRNREKVEQTILPLKENTLYYEKTEPSRPSQTEVADYQVELTDEGQDLT
                     LFAKETLDRLTKPAKLHFAERKPANYDQLDHPELDLASIDKAYDKLEREEASSFPELE
                     FFGQMHGTYLFAQGRDGLYIIDQHAAQERVKYEEYRESIGNVDQSQQQLLVPYIFEFP
                     ADDALRLKERMPLLEEVGVFLAEYGENQFILREHPIWMAEEEIESGIYEMCDMLLLTK
                     EVSIKKYRAELAIMMSCKRSIKANHRIDDHSARQLLYQLSQCDNPYNCPHGRPVLVHF
                     TKSDMEKMFRRIQENHTSLRELGKY"
     gene            complement(2290..2757)
                     /locus_tag="VQ540_001604"
     CDS             complement(2290..2757)
                     /locus_tag="VQ540_001604"
                     /EC_number="2.5.1.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6,7-dimethyl-8-ribityllumazine synthase"
                     /protein_id="HET2545378.1"
                     /translation="MNTYEGNLVANNIKIGIVVARFNEFITSKLLSGALDNLKRENVN
                     EKDIEVAWVPGAFEIPLIASKMAKSKKYDAIICLGAVIRGNTSHYDYVCSEVSKGIAQ
                     ISLNSEIPVMFGVLTTDTIEQAIERAGTKAGNKGSECAQGAIEMVNLIRTLDA"
     gene            complement(2758..3963)
                     /locus_tag="VQ540_001605"
     CDS             complement(2758..3963)
                     /locus_tag="VQ540_001605"
                     /EC_number="3.5.4.25"
                     /EC_number="4.1.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP
                     cyclohydrolase II"
                     /protein_id="HET2545379.1"
                     /translation="MEYRKIQEALEALQKGRLVLVIDDKDRENEGDLICSAQAATTEN
                     VNFMATYAKGLICMPMSESLANQLMLSPMVENNTDNHKTAFTVSIDYKETTTGISAEE
                     RGLTARMCVAEDITPSDFRRPGHMFPLIAKKGGVLERNGHTEATVDLLKLAGLKECGL
                     CCEIMNHDGKMMRTDDLIQFSKKHNIPLITIKELQEYRKVYDQLVERVSTVNMPTRYG
                     NFKAISYIDKLNGEHHLALIMGNIEDEANVLCRVHSECLTGDVLGSLRCDCGQQFDKA
                     MKMIVENGSGVLLYLRQEGRGIGLINKLKAYHLQDQGMDTLDANLALGFEGDLREYHI
                     GAQMLKDLGLQSLHLLTNNPDKVEQLEKYGITISSRISIEIEANPYDSFYLETKKNRM
                     GHILNMEEK"
     gene            complement(3983..4618)
                     /gene="ribE"
                     /locus_tag="VQ540_001606"
     CDS             complement(3983..4618)
                     /gene="ribE"
                     /locus_tag="VQ540_001606"
                     /EC_number="2.5.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin synthase"
                     /protein_id="HET2545380.1"
                     /translation="MFTGIIEEIGKVERIQKDSRNCKLSIKASKILTDIHLGDSIAVN
                     GICLTVTHFNHQSFTVDVMNETWSRTALTLLKHGSEVNLERALSVNGRLGGHVVTGHI
                     DGTGKISSIKKDDNAVWYQINTQKEILDLIVEKGSITIDGISLTVAKVSKVNFSVSVI
                     PHTLEQTILKSKQVGSTVNLENDILGKYVQKLMDNSPKSEISKELLYQNGF"
     gene            complement(4603..5703)
                     /gene="ribD"
                     /locus_tag="VQ540_001607"
     CDS             complement(4603..5703)
                     /gene="ribD"
                     /locus_tag="VQ540_001607"
                     /EC_number="1.1.1.193"
                     /EC_number="3.5.4.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     diaminohydroxyphosphoribosylaminopyrimidine
                     deaminase/5-amino-6-(5-phosphoribosylamino)uracil
                     reductase RibD"
                     /protein_id="HET2545381.1"
                     /translation="MSDSKYMKLAIKLAQKGAGYVNPNPMVGAVIVKDNHIIGQGYHE
                     FFGGPHAERNALKNCRESPVGATLYVTLEPCCHFGKTPPCIDAIIDSGITRVVIGSLD
                     CNPIVSGKGVKILEENNLQVTVGILENECLNLIKSFRKYITQHVPYVFMKYAMSMDGK
                     IATKTNQSKWITEEEARKHVHQLRHHVSAIMVGVNTVIQDDPLLTCRLEEGKNPIRII
                     CDTHLRTPLTSKIVKTANDIKTYIATSSEDKNKMKLYQNHGCEILSIKKKGNHIDLSS
                     LMQHLGNMQIDSLVLEGGSLMNWSALEQQIVDELKIYIAPKIFGGSAKFPVGGEGISL
                     PNDAIRLKPYAFSQIGNDYLIESEVIYPCSQE"
     regulatory      complement(5838..5952)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            6109..6702
                     /gene="ruvA"
                     /locus_tag="VQ540_001608"
     CDS             6109..6702
                     /gene="ruvA"
                     /locus_tag="VQ540_001608"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000271492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HET2545382.1"
                     /translation="MYAYLKGIITKITAKYIVLETNGIGYILHVANPYAYSGQVNQEA
                     QIYVHQVVREDAHLLYGFRSEDEKKLFLSLISVSGIGPVSALAIIAADDNAGLVQAIE
                     TKNITYLTKFPKIGKKTAQQMVLDLEGKVVVAGDGLPAKVAVQASAENQELEEAMEAM
                     LALGYKATELKKIKKFFEGTTDTAENYIKSALKMLVK"
     gene            6712..7275
                     /locus_tag="VQ540_001609"
     CDS             6712..7275
                     /locus_tag="VQ540_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HET2545383.1"
                     /translation="MTKRCSWVKMTNPLYIAYHDEEWGQPLHDDQALFELLCMETYQA
                     GLSWETVLNKRQAFREAFHSYQIHSVAEMTDTELEAMLENPAIIRNRAKIFATRANAQ
                     AFLQLQAEYGSFDAYLWSFVEGKTVVNDVPDYRQAPAKTPLSEKLAKDLKKRDFKFTG
                     PVAVLSFLQAAGLVDDHENDCEWKGLK"
     gene            7272..7949
                     /locus_tag="VQ540_001610"
     CDS             7272..7949
                     /locus_tag="VQ540_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000987430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET2545384.1"
                     /translation="MMSNKNKGILIFAILYTVLFVFDGVKLLASLMPSAIANYLVYVV
                     LALYGSFLFKDRLIQQWKEIRKTKRKFFFGVLTGWLFLILMTVVFEFVSEMLKQFVGL
                     VGQGLNQSNIQSTFQEQPLLIAVFACVIGPLVEELFFRQVLLHYLQERLPGLLSIILV
                     GLVFALTHMHSLALSEWIGAVGYLGGGLAFSIIYVKEKENIYYPLLVHMLSNSLSLII
                     LAISIVK"
     gene            complement(8090..9121)
                     /locus_tag="VQ540_001611"
     CDS             complement(8090..9121)
                     /locus_tag="VQ540_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000255096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HET2545385.1"
                     /translation="MVSTIGIVSLSSGIIGEDFVKHEVDLGIQRLKDLGLNPIFLPHS
                     LKGLDFIKDHPEARAEDLIHAFSDDSIDMILCAIGGDDTYRLLPYLFENDQLQKVIKQ
                     KIFLGFSDTTMNHLMLHKLGIKTFYGQSFLADICELDKEMLAYSLHYFKELIETGRIS
                     EIRPSDVWYEERTDFSPTALGTPRVSHTNTGFDLLQGRALFEGKILGGCLESLYDIFD
                     NSRYADSTELCQKYKLFPDLSDWEGKILLLETSEEKPKPEDFKKMLLTLKDTGIFAVI
                     NGLLVGKPMDETFHDDYKEALLDIIDSNIPIVYNLNAGHATPRAIVPFGVHAHVDAQE
                     QVIRFDYNK"
     gene            complement(9376..10059)
                     /locus_tag="VQ540_001612"
     CDS             complement(9376..10059)
                     /locus_tag="VQ540_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HET2545386.1"
                     /translation="MSQIDLQKLTKKNQEFVHIATQQFIKDGKTDAEIQTIFEEVIPQ
                     ILEEQSKGTTARSLYGAPTHWAHSFTVKEQYEKEHPKENDDPKLMIMDSALFITSLFA
                     LVSALTTFFAADQAFGYGLITLLLVGLVGGFAFYLMYYFVYQYYGPDMDRSQRPPFWK
                     SVLVILASVFLWLLVFFATSFLPASLNPVLDPLPLAIIGAALLALRFYLKKRLNIRSA
                     SAGPTRYQE"
     gene            complement(10071..11015)
                     /locus_tag="VQ540_001613"
     CDS             complement(10071..11015)
                     /locus_tag="VQ540_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HET2545387.1"
                     /translation="MKQVFLSTTTEFKEIDTLEPGTWINLVNPTQNESLEIANTFDID
                     IADLRAPLDAEEMSRITIEDEYTLIIVDVPVTEERNNRTYYVTIPLGIIITEETIITT
                     CLEPLPVLDVFINRRLRNFYTFMRSRFIFQILYRNAELYLTALRSIDRKSEQIESQLH
                     QSTRNEELIELMELEKTIVYFKASLKTNERVIKKLTSSTSNIKKYLEDEDLLEDTLIE
                     TQQAIEMADIYGNVLHSMTETFASIISNNQNNIMKTLALVTIVMSIPTMVFSAYGMNF
                     KDNEIPLNGEPNAFWLIVFIAFAMSVSLTLYLIHKKWF"
     gene            11147..13978
                     /gene="uvrA"
                     /locus_tag="VQ540_001614"
     CDS             11147..13978
                     /gene="uvrA"
                     /locus_tag="VQ540_001614"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HET2545388.1"
                     /translation="MQDKIVIHGARAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFD
                     TLYAEGQRRYVESLSAYARQFLGNMEKPDVDAIDGLSPAISIDQKTTSKNPRSTVGTT
                     TEINDYLRLLYARVGTPYCINGHGAIKASSVEQIVDKVLELPERQRLQILSPVIRKKK
                     GQHKSVIEKVQKDGYVRVRVDGEVYDVTEVPELSKSKQHNIDVVVDRIVIKEGIRSRL
                     FDSIEAALRIAEGYVIIDTMDNSELLFSEHYACPVCGFTVPELEPRLFSFNAPFGSCS
                     ECDGLGIKLEVDTDLVVPNASKTLHEGALAPWNPISSNYYPNMLEQAMTAFGVAMDKP
                     FEDLSEEDKNLILYGSDGKKFHFHYENEFGGVRDIDIPFEGVINNIKRRYHETNSDYT
                     RTQMRLYMNELTCGTCHGYRLNDQALSVRVGGEQGPHIGEISDLSIADHLDLVSQLTL
                     SENEAIIARPILKEIKDRLTFLNNVGLNYLTLSRSAGTLSGGESQRIRLATQIGSNLS
                     GVLYILDEPSIGLHQRDNDRLIASLKKMRDLGNTLIVVEHDEDTMREADYLIDVGPGA
                     GVFGGEIVAAGTPKQVARNSKSITGQYLSGKRVIPVPEERRVGNGRFIEVIGARENNL
                     QNVTARFPLGKFIAVTGVSGSGKSTLINSILKKAIAQKLNRNSDKPGKFKTITGIEHV
                     DRLIDIDQSPIGRTPRSNPATYTGVFDDIRDLFAQTNEAKIRGYKKGRFSFNVKGGRC
                     EACSGDGIIKIEMHFLPDVYVACEVCHGTRYNSETLEVHYKEKNISQVLDMTVNDAVE
                     FFQHIPKIQRKLQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSFYIL
                     DEPTTGLHTEDIARLLKVLARFVDDGNTVLVIEHNLDVIKTADHIIDLGPEGGVGGGT
                     IIVTGTPEEVAANEASYTGHYLKGKLHHE"
     gene            13971..15032
                     /locus_tag="VQ540_001615"
     CDS             13971..15032
                     /locus_tag="VQ540_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HET2545389.1"
                     /translation="MNKRVQAFLAKMQEKELDGVIINNLKNVYYLTGFWGSNGTVFIS
                     RDRQVLVTDSRYIIAAKQETSGFEIVADRDELAVIAGIVKDMGLTRIGFEDEISVSYY
                     HRMQAAFAGLNLLPQTQFVEGLRMIKDEAEIAAIRKACSISDQAFRDALDFIKPGKTE
                     IEIANFLDFRMRELGASGLSFDTILASGINSSKPHAHPMHKPVELGEAITMDFGCLYD
                     HYVSDMTRTIYLGHVSDEQAEIYNTVLKANQALIDQAKAGLGFRDFDKIPRDIIIEAG
                     YGDYFTHGIGHGIGLDIHEEPYFSQTSTETIKTGMALTDEPGIYIEGKYGVRIEDDIL
                     ITETGCELLTLAPKELIVI"
BASE COUNT         4257 a         3039 c         3219 g         4568 t
ORIGIN      
        1 gaaaggggct gaaagatgtc tcatattatt gaattgccag agatgctggc aaaccaaatc
       61 gcagctggag aggtcattga acgtcctgcc agcgtggtca aagaattggt agaaaatgcc
      121 attgacgcgg gctctagtca gattatcatt gagattgagg aagctggtct caagaaaatc
      181 caaatcacag ataacggtta tggaattgcc cacgatgagg tggagttggc cctgcgtcgc
      241 catgcgacca gtaagataaa aaatcaagca gatctctttc ggattcggac gcttggtttt
      301 cgtggtgaag ccttgccttc tattgcgtct gttagtgtct tgactctgtt aacggcggtg
      361 gatggtgcta gtcatggaac caagttagtc gcgcgtgggg gtgaagttga ggaagtcatc
      421 ccagcgacta gtcctgtggg aaccaaggtt tgtgtggagg atctcttttt caacacgcct
      481 gcccgtctca agtatatgaa gagccagcaa gcggagttgt ctcatatcat tgatattgtc
      541 aaccgtctgg gcttggccca tcctgagatt tcttttagct tgattagtga tggcaaggaa
      601 atgacgcgga cagcagggac tggtcaattg cgccaagcaa tcgcagggat ttacggtttg
      661 gtcagtgcca agaagatgat tgaaattgag aactctgacc tagatttcga aatttcaggt
      721 tttgtgtcct tgcctgagtt gactcgggct aaccgcaatt atatcagcct cttcatcaat
      781 ggtcgttata tcaagaactt cctgctcaat cgtgctattt tggatggttt cggaagcaag
      841 cttatggttg gacgttttcc actggctgtc attcacatcc atatcgaccc ttatctagcg
      901 gatgtcaatg tgcatccaac taagcaagag gtgcggattt ccaaggaaaa agaactgatg
      961 accctggttt cagaagctat tgcaaatagt ctcaaggaac aaaccttgat tccagatgcc
     1021 ttggaaaatc ttgccaaatc gactgtgcgc aatcgtgaga aggtggagca aactattctc
     1081 ccactcaaag aaaatacgct ctactatgag aaaactgagc cgtcaagacc tagtcaaact
     1141 gaagtagctg attatcaggt agaattgact gatgaagggc aggatttgac cctgtttgcc
     1201 aaggaaacct tggaccgatt gaccaagcca gcaaaactgc attttgcaga gagaaagcct
     1261 gctaactacg accagctaga ccatccagag ttagatcttg ctagcatcga taaggcttat
     1321 gacaaactgg agcgagaaga agcatccagc ttcccagagt tggagttttt cggacaaatg
     1381 cacgggactt atctctttgc ccaagggcga gatggacttt acatcataga tcagcacgct
     1441 gctcaggaac gggtcaagta cgaggagtac cgtgaaagca ttggcaatgt tgaccagagc
     1501 cagcagcaac tcctagtgcc ctatatcttt gaatttcctg cggatgatgc cctgcgtctc
     1561 aaggaaagaa tgcctctctt agaggaagtg ggcgtctttc tagcagagta cggagaaaat
     1621 caatttattc tacgtgaaca tcctatttgg atggcagaag aagagattga atcaggcatc
     1681 tatgagatgt gcgacatgct ccttttgacc aaggaagttt ctatcaagaa ataccgagca
     1741 gagctggcta tcatgatgtc ttgcaagcga tctatcaagg ccaatcatcg tattgatgat
     1801 cattcagcta gacaactcct ctatcagctt tctcaatgtg acaatcccta taactgtcct
     1861 cacggacgtc ctgttttggt gcattttacc aagtcggata tggaaaagat gttccgacgt
     1921 attcaggaaa atcacaccag tctccgtgag ttggggaaat attaaaagta taaaaaagtc
     1981 tgggaaaaat tttcaaaatc agaaaaacgc ataaaatcag gtgttcaaaa accttgattt
     2041 tatgcgtttt atcatggaaa tagttacttc atgttttcct aattcttttc gaaactcttt
     2101 ttaaaccacg tcagttttat cagtaatctc aaaacagtgt tttgagctaa ttttgccagt
     2161 tttatctgta acatcgaagt tgtgtttgac cactctgcga ctggtttcct agtttgctct
     2221 atgattttca cagagtatta aattgcgatt ttgccaagtt tctttattcg tctaaaagta
     2281 gagtctgttc tatgcgtcta atgtacgaat taggttgacc atttcaatag ctccttgtgc
     2341 acactcagaa cccttatttc ctgctttggt accagctcgt tctatggctt gttcaattgt
     2401 atctgtcgtt agcacaccaa acataacagg aatttcgcta tttaaactga tttgggcgat
     2461 tcccttagat acctcgctac atacataatc ataatgactt gtattccctc taatgacagc
     2521 tcccaagcag ataattgcat catatttttt actttttgcc atttttgatg caatcagtgg
     2581 tatttcaaaa gctcctggaa cccaggctac ctctatatct ttctcgttta cattctctct
     2641 tttgagatta tctagtgctc cagataataa ttttgaagtt ataaattcat taaatctcgc
     2701 tacaacaata cctattttaa tattgtttgc tactaaatta ccttcataag tgttcattta
     2761 tttttcctcc atatttaaaa tgtgacccat tcgatttttc tttgtttcta aataaaaact
     2821 atcgtaagga ttggcttcta tttcgattga tattctactg gaaatggtaa ttccatattt
     2881 ttctaactgt tcaaccttgt caggattatt tgtcagtaaa tgaagtgact gaagtcccag
     2941 atctttaagc atttgtgctc caatatgata ttctcttaaa tcaccttcaa agcctaatgc
     3001 aagattggca tcaagcgtat ccatgccttg atcttgtaaa tgataggctt ttaatttatt
     3061 gataagtcca attcctcgtc cctcctgtcg caagtaaagt aagacacccg aaccattctc
     3121 aacaatcatt ttcatagctt tatcgaattg ctgtccacaa tcgcaacgta aagagcctaa
     3181 aacatctcct gttaaacatt cggagtggac ccgacataat acattggctt catcctctat
     3241 atttcccata ataagagcaa gatgatgttc cccatttagt ttatctatat agctaattgc
     3301 tttgaaatta ccgtatctag taggcatatt gacagttgaa actcgttcta ccagctgatc
     3361 atatactttt ctatattctt gtaattcttt gatggtaatt agtggaatgt tgtgtttctt
     3421 cgagaactga attaaatcat ctgttctcat cattttgcca tcatgattca ttatttcaca
     3481 acataggcca cactctttta gtccagctaa ttttaataaa tcaacagttg cttctgtgtg
     3541 tccatttctt tctagaacac cacctttttt tgcaattaaa ggaaacatgt gtcctggcct
     3601 gcgaaaatca gagggtgtta tatcttcagc tacacacata cgtgcggtca gtcctctctc
     3661 ctcggcagaa atacctgtgg tcgtttcttt ataatcaatt gaaactgtaa aagcagtctt
     3721 atgattatct gtattgtttt caaccatagg tgaaagcatt aattgattag ctaaactttc
     3781 gctcataggc atacaaatta atcctttggc ataagtagcc ataaaattaa cattttctgt
     3841 tgtagctgct tgtgcagaac aaattaagtc tccttcattt tctctatcct tgtcgtctat
     3901 aacaagaaca agtcgtccct tctgcaatgc ttctaatgct tcttgtattt ttcgatattc
     3961 cattgactga ttatcctttc tgctaaaatc cattttgata taatagttcc ttagatattt
     4021 ctgattttgg agagttatcc atcagttttt gcacatattt acctaagata tcattttcaa
     4081 gatttactgt actcccgact tgtttactct taagaatggt ttgttccaag gtatgaggga
     4141 taacagatac tgaaaagttt actttggaga ctttagcgac agtcagacta atgccgtcaa
     4201 ttgtaataga tcctttttca actattaaat ctaaaatttc tttttgtgtg ttgatttgat
     4261 accatacagc attatcatct ttttttattg acgagatttt tcctgtacca tcaatgtgtc
     4321 ctgtaacgac gtgaccccca agtcgaccgt tgacagataa ggctctttct agattcacct
     4381 cacttccatg ttttaataga gtaagagctg ttcgactcca tgtttcattc attacatcaa
     4441 ctgtaaagga ttgatgattg aaatgagtaa ctgtaagaca gataccattt actgctatac
     4501 tatcgcctaa atggatatcc gttaatattt ttgaggcttt aattgatagt ttacaattac
     4561 gagagtcttt ctgtattctt tcaacttttc cgatttcttc aattattcct gtgaacatgg
     4621 ataaatcact tcactttcta tgagatagtc atttcctatt tgagaaaaag cataaggttt
     4681 caatctaata gcgtcatttg gcaaagaaat gccttcacct ccgacaggaa acttggcact
     4741 gcctccaaaa atttttggtg caatatatat tttcagctca tcaacaattt gttgttccaa
     4801 agcactccaa ttcattagac tgcccccttc tagaactagg ctatcaatct gcatgtttcc
     4861 tagatgttgc attaaactcg ataagtctat atgattgcct tttttcttta tggaaagtat
     4921 ttcacagcca tgattttgat atagcttcat tttatttttg tcttcagagg aagtggcaat
     4981 gtaagtttta atatcatttg ctgtttttac gattttagag gtaagaggag ttcgtaaatg
     5041 tgtatcgcat atgatacgga taggattttt cccttcctcc aatctacatg tcagcaaagg
     5101 atcgtcttga ataacagtat tgactcccac cataattgca ctaacatggt gtcgtaactg
     5161 atgcacatgc tttcttgctt cttcttcagt aatccatttg gattgatttg ttttagtggc
     5221 tatttttcca tccattgaca ttgcatattt cataaaaaca tagggtacat gctgggtaat
     5281 atactttcta aaacttttta ttaagttaag acactcattt tctaaaattc caacagtaac
     5341 ttgaagatta ttttcctcaa gtatctttac tccttttcca gatacaatag gattacagtc
     5401 taggcttcca atgactactc ttgtaatacc actatcgatt atagcatcta tacagggagg
     5461 tgttttcccg aagtgacaac agggttcaag tgttacataa agcgtcgctc cgacagggga
     5521 ttctctacag tttttaagag catttctctc agcatgtggg ccaccaaaaa actcatgata
     5581 accttgtccg atgatgtgat tatcttttac aataactgcg ccgaccatag gattgggatt
     5641 gacgtaacca gccccttttt gtgccagttt tattgctaat ttcatatatt ttgaatcgct
     5701 catctcacta cctccaaaaa aaatatacct tgaatagggg actactcaag gcatacaaaa
     5761 gaaaacttat gcgattaaca aaaatactct gaaatgacaa gtaatcattt cagagcacgc
     5821 aaaaagcaca aatatacttt tatcttcttt catccagact atactgtcgg ctttggaatt
     5881 tcaccaaatc atgcctttcg gctcgtgggc tataccaccg gtagggaatt acaccctgcc
     5941 ctgaagatag ttattcaatt acagatgatt atagtactta attttgaata tgtcaacaga
     6001 taaataccga ttgtttttga tatactgtat ttgtgataat cgattctcgc tcctcggata
     6061 aagaaaatat gatatactag ataaacgaaa taagagagaa ggaatactat gtacgcatat
     6121 ttaaaaggaa tcattaccaa aattactgcc aaatacattg ttcttgaaac caatggtatt
     6181 ggttatatcc tgcatgtggc caatccttat gcctattcag gtcaggttaa tcaggaggct
     6241 cagatttatg tgcatcaggt tgtgcgtgag gacgcccatt tgctttatgg atttcgctca
     6301 gaggatgaga aaaagctctt tcttagtctg atttcggtct ctgggattgg tcctgtatca
     6361 gctcttgcta ttatcgctgc tgatgacaat gctggcttgg ttcaagccat tgaaaccaag
     6421 aacatcacct acttgaccaa gttccctaaa attggcaaga aaacagccca gcagatggtg
     6481 ctggacttgg aaggcaaggt agtagttgca ggagatggcc ttcctgccaa ggtcgcagtg
     6541 caagcaagtg ctgaaaacca agaattggaa gaagctatgg aagccatgtt ggctctgggc
     6601 tacaaggcaa cagagctcaa gaaaatcaag aaattctttg aaggaacgac agatacagct
     6661 gagaactata tcaagtcggc ccttaaaatg ttggtcaaat aggagcagag aatgacaaaa
     6721 cgttgttcgt gggtcaagat gaccaaccca ctctacatcg cctatcatga tgaggagtgg
     6781 ggccagcccc tccatgatga ccaagcgttg tttgagttat tgtgtatgga aacctatcag
     6841 gcaggcctgt cttgggaaac ggtactcaac aaacgccaag ctttccgaga agcctttcat
     6901 agctatcaaa ttcactcagt cgcagagatg actgacactg aattggaagc catgctggag
     6961 aatccagcta tcattcgaaa tagagccaag atttttgcta cacgcgctaa cgcccaagct
     7021 tttctacagt tacaggcaga gtacggctct tttgatgcct atctttggtc ttttgttgag
     7081 gggaaaactg tcgttaacga tgttcctgat tatcgccaag ccccagctaa aacaccctta
     7141 tctgagaaat tagccaaaga tctcaaaaaa cgagacttca agttcacagg cccagtcgcc
     7201 gtattgtctt ttctacaggc tgcagggcta gttgatgacc acgagaatga ttgtgagtgg
     7261 aaaggtctta aatgatgtct aacaaaaata agggaattct gatttttgcg attctctata
     7321 cagtcctctt tgtgtttgat ggcgttaaat tgctggcttc tttaatgcca tctgccattg
     7381 caaattatct tgtttatgta gttttagctc tatatggctc cttcttattc aaggatagat
     7441 tgatccaaca atggaaggag attagaaaga ctaaaagaaa attcttcttt ggcgtcttaa
     7501 caggatggct ctttctcatt ctgatgactg ttgtctttga atttgtatca gagatgttga
     7561 agcagtttgt ggggctagtc ggacaaggtc taaatcagtc taatattcaa agcacttttc
     7621 aagagcaacc actactgata gctgtttttg cttgtgtcat tggacctctg gtagaagaat
     7681 tatttttccg tcaggtctta ttgcattact tgcaggaacg gttgccaggt ttactaagca
     7741 ttattctggt aggacttgtt tttgctctga ctcatatgca cagtttggct ctatcagagt
     7801 ggattggtgc agttggttac ttaggtggag gccttgcctt ttctattatt tatgtgaaag
     7861 aaaaagagaa tatctactat ccactacttg ttcacatgtt aagcaacagc ctctccttaa
     7921 tcattttagc tatcagtata gtaaaatgaa ataagaacag gacagtcaaa tcgatttcta
     7981 acaatgtttt agaagtagat gtgtactatt ctagtttcaa tttgctgtaa tatgtgatga
     8041 aaatgccagt aatgataccg agaaaaaagc tgagaaactt ttcccagctt tatttgttat
     8101 agtcaaagcg aatgacttgt tcctgtgcat ctacatgagc atggacccca aagggtacaa
     8161 ttgctcttgg agttgcgtgg ccggcattca gattatagac aatcgggata ttgctgtcaa
     8221 tgatatccaa tagtgcctct ttatagtcgt catggaaagt ttcatccata ggttttccga
     8281 ccaagagtcc attgatgacc gcgaatatgc cagtgtcctt taaagttagc aacatctttt
     8341 tgaagtcttc tggcttaggc ttttcttcgc ttgtttcgag caagaggatt ttcccttccc
     8401 agtctgacaa gtcagggaaa agtttgtatt tttggcagag ctccgtgcta tctgcgtatc
     8461 gagagttgtc aaagatatcg tagagggatt cgaggcaacc accgaggatt ttcccctcga
     8521 atagtgccct tccttgcaac aagtcaaaac ctgtatttgt atgactgaca cgaggtgttc
     8581 ccagggccgt gggactaaaa tcagttcgtt cctcatacca aacgtcacta gggcggattt
     8641 ctgaaattct tcccgtctca atcaattctt taaagtagtg aaggctatag gctagcattt
     8701 ctttgtctaa ttcacaaatg tctgctaaaa aggattgacc ataaaaagtc ttgattccta
     8761 atttatgcaa catgaggtgg ttcatggttg tatccgagaa gccaagaaaa attttttgct
     8821 tgataacctt ttggagttgg tcattttcaa aaagataagg tagcaagcga taggtatcgt
     8881 ctccaccgat ggcacatagg atcatgtcga tgctatcatc agaaaaggca tgaatcaaat
     8941 cctctgcacg agcttcagga tggtccttga taaagtctaa tccttttaac gaatggggca
     9001 aaaagatggg attgagtccc agatccttga gacgttggat acccaagtcc acttcgtgtt
     9061 tgacaaaatc ctctccgata atgccactag ataaactaac aataccaata gtagaaacca
     9121 tatctcatcc tcctagaaat agattgagcc tattttatca caaaatataa gagaaagcta
     9181 tgtgggattt cagaagaata cttttaatac tcttcgaaaa tctcttcaaa ccacgtcagt
     9241 tttatctgca acctcaaagc tgtgctttga gcaacctgca gctagcttcc tagtttgctc
     9301 tttgattttc attgagtata actcaaaaaa gtaagtgaaa aagcaaccgc acctgcagtt
     9361 gcttttatcg ttttcttatt cttgatagcg tgttggtcct gcacttgcac tacggatatt
     9421 caagcgtttc ttgagataga agcgaagggc taggagggct gctccaataa tagctagtgg
     9481 caatggatcc agtactgggt taaggctagc tggtaggaag cttgttgcaa agaagacaag
     9541 caaccaaagg aacacagaag ctaggataac tagtacagat ttccagaaag gtggacgttg
     9601 actgcgatcc atatctggtc catagtattg gtaaacaaag tagtacatca agtagaaggc
     9661 aaatccacca accagtccaa ctaatagaag agtaatcaat ccatagccga aagcttgatc
     9721 tgccgcaaag aaggttgtga gggcgctgac aagggcaaag aggctagtga tgaaaagagc
     9781 tgagtccata atcatcagtt ttgggtcatc attttctttt ggatgctctt tttcgtactg
     9841 ctctttgaca gtgaagctat gagcccaatg agttggtgcg ccgtataggg aacgggcagt
     9901 tgtaccttta gattgctcct caaggatttg gggaatgact tcctcaaaaa tagtctggat
     9961 ttcagcgtct gttttcccat ctttgatgaa ttgttgggta gcaatgtgga caaactcttg
    10021 gtttttctta gttaattttt gtagatcaat ttgagacata ggaactcctt ttagaaccat
    10081 tttttatgga tgagatagag agtgagcgag acactcatag caaaggcgat aaagacgatt
    10141 aaccagaagg catttggctc tccgtttagg ggaatttcat tatccttaaa gttcatcccg
    10201 taggcagaaa agaccatggt tgggatggac atgacgatgg tcacaagggc caaggttttc
    10261 atgatgttgt tctggttgtt agaaatgata gaggcaaagg tctctgtcat agaatgcaag
    10321 acgtttccat aaatatctgc catctcgatg gcctgttggg tttcaatcag ggtgtcttca
    10381 agcaggtctt cgtcctcaag gtatttcttg atattgctgg ttgaactggt caatttctta
    10441 atcacgcgct catttgtttt gagggaggcc ttgaaataga cgatagtttt ttccaattcc
    10501 atgagctcaa tcaattcttc attacgagtt gattgatgca gttgactttc gatttgttca
    10561 ctcttgcggt cgattgaacg aagggctgtt aggtaaagct ctgcattgcg ataaagaatt
    10621 tgaaagataa aacgtgaacg catgaaggta tagaaattac gcaatcgacg gttgataaag
    10681 acatcaagga caggtagtgg ttccaaacac gtagtgataa tggtttcctc agtgatgata
    10741 ataccaagcg ggatggttac gtagtaggtg cggttatttc tttcctccgt gaccggcacg
    10801 tctacgataa tcagggtata ctcgtcttca atggtaatac gagacatttc ttccgcatcg
    10861 agcggtgctc gaaggtcggc aatatcaata tcgaaggtgt tggcgatttc gagtgattca
    10921 ttttgagtcg gattgacgag attgatccaa gtacccggtt caagcgtatc gatctcttta
    10981 aattcagttg ttgtagagag aaaaacttgt ttcatatccc ttatcctttc tcatttttca
    11041 gattttttca cactgtacta ttatactaca aaatcggcct tttgggtaat agaatctcac
    11101 tttttttggt ataatggtaa gcaataatgg actagaaaga acaaagatgc aagataaaat
    11161 tgtcattcat ggggcgcgtg cccataattt aaaaaatatt gatgtggaga ttccgcgaga
    11221 caagttggtt gtcgtgactg gcttgtcagg ttcagggaag tccagtttgg cttttgatac
    11281 cctctatgcg gagggacaac gtcgctatgt agagagtttg tccgcctacg ctcgtcagtt
    11341 cttgggaaat atggaaaaac cagatgtaga tgccattgat ggtctcagcc cagctatttc
    11401 tatcgaccag aaaacgacta gcaaaaaccc tcgctcgacg gtgggaacaa cgactgaaat
    11461 caatgactat ctgcgtctcc tctacgcgcg tgtggggacg ccttactgta tcaacgggca
    11521 tggggctatc aaggcttctt ctgtggagca aatcgttgat aaggttttgg agttacctga
    11581 acgccagcgc ttgcagatct tgtctcctgt catccgcaag aaaaaaggcc aacataagag
    11641 tgttatcgag aaggttcaga aagacgggta tgttcgtgtc cgtgtggatg gggaagtcta
    11701 tgatgtgacc gaagtgccag agttgtctaa gagcaagcaa cacaatatcg atgtcgtggt
    11761 tgaccgtatt gttatcaagg agggcattcg tagtcgtctc tttgattcca ttgaggctgc
    11821 ccttcgtatt gcagaaggtt atgtcattat cgacaccatg gacaactctg agttgttgtt
    11881 ctctgagcat tatgcctgtc cagtttgtgg ttttactgtc ccagagttag agcctcgtct
    11941 cttttctttc aatgctcctt ttggctcttg tagtgagtgt gacggcttgg gcatcaagct
    12001 ggaggtggat actgatttgg tagtgccaaa tgccagcaaa accttacatg agggagcgct
    12061 ggcaccttgg aatcctatct catccaacta ctatccaaac atgctagagc aggccatgac
    12121 ggcttttgga gtggctatgg ataagccttt tgaggacttg tcagaagaag acaagaactt
    12181 gattctctac ggctcagatg gtaagaaatt ccatttccac tatgagaatg aatttggtgg
    12241 cgtgcgcgat atcgacattc cgtttgaggg agttatcaat aatatcaaac gtcgttacca
    12301 tgaaaccaat agcgattaca ctcgcactca gatgcgcctc tacatgaatg agctgacttg
    12361 cggaacctgt cacggttatc gtctcaatga ccaggccttg tctgtccgtg tgggtggtga
    12421 gcaagggcca catatcggag aaatttcaga cctgtctatc gcagatcact tggacttggt
    12481 gagccagtta actttgtctg aaaatgaagc catcattgct cgtcccattc tcaaggaaat
    12541 caaggatcgt ttgaccttcc ttaataatgt gggtcttaac tatctaaccc tgtcacgttc
    12601 agcaggaacc ctttcaggtg gggaaagtca gcgcattcgt ttggcaaccc agattggttc
    12661 caacctatca ggcgtcctct atatcctaga cgagccgtca atcggtcttc accagagaga
    12721 caatgaccgc ctgattgcca gtctgaaaaa gatgcgtgac ttgggcaata ctcttatcgt
    12781 ggtggaacac gacgaagata ccatgcgtga agctgattat ctgattgacg ttggtcctgg
    12841 tgccggtgtt tttggtggtg agattgttgc agcaggtaca cctaagcaag tggctcgcaa
    12901 cagcaagtct atcacaggtc agtacttgtc aggcaaacgt gtcatcccag taccagaaga
    12961 gcgccgtgtc ggaaatggtc gttttattga agtgatagga gcgcgtgaga acaacttgca
    13021 aaatgtcacg gctcgctttc cactaggaaa atttatcgca gtgacaggtg tgtcgggttc
    13081 agggaaatcg actctaatca acagcattct caaaaaagcc attgcccaga agctcaaccg
    13141 taattcagac aaacctggta agtttaagac tattacaggg attgagcatg tcgaccgttt
    13201 gattgatatt gaccagagcc ctatcggacg gacgccgagg tctaacccag ctacctatac
    13261 aggagttttt gacgatatac gtgacctttt tgctcagaca aatgaagcca agattcgagg
    13321 ctacaagaag ggacgcttca gtttcaacgt caagggaggt cgctgtgaag cttgctcagg
    13381 tgacgggatt atcaagattg agatgcactt cttgccagat gtttatgtgg cttgtgaagt
    13441 ttgccacgga acccgctata acagtgaaac cctagaagtt cactacaagg aaaagaatat
    13501 ttcgcaggtc ttggatatga cggtcaacga tgcggtagaa tttttccaac acattccgaa
    13561 aattcaacgc aaactccaga ccatcaagga tgtagggcta ggctatgtga ccttgggaca
    13621 gccagctacc accctttctg ggggagaagc ccaacgtatg aagttagcta gcgaactcca
    13681 caaacgctcg acaggaaaat ctttctacat tctggatgaa ccgacgacag ggcttcatac
    13741 agaggacatt gctcgcctgc tcaaggtttt agctcgcttt gtagacgatg gcaatacagt
    13801 cctcgtcatc gagcacaatc tggatgttat caagacggca gaccatatca ttgacttggg
    13861 acctgagggc ggtgtcggtg gtggaaccat catcgtaaca ggaactccag aagaagtagc
    13921 tgccaacgaa gccagctata caggacacta tttgaaagga aagttacatc atgaataaac
    13981 gcgtacaagc atttctagct aaaatgcaag aaaaagaact agatggtgtc atcatcaaca
    14041 atcttaaaaa cgtctattat ttgactggtt tttggggctc aaacggaaca gtctttatca
    14101 gccgtgaccg tcaggtatta gtgacagact ctcgctatat catcgcagct aagcaagaaa
    14161 ccagtggttt tgagattgtg gctgatcgtg atgaattggc tgtcattgca ggaattgtta
    14221 aggacatggg cttgactcgt atcggttttg aagatgagat ttcagtgtct tattaccacc
    14281 gtatgcaggc agcttttgca ggtttgaact tgcttccaca aactcagttt gtggaaggtc
    14341 ttcgtatgat taaggatgag gcagagattg cagcgattcg caaggcttgt tctatctcag
    14401 accaagcttt ccgcgatgcg cttgacttta tcaaaccagg aaaaactgaa attgagattg
    14461 ccaacttcct tgatttccgc atgcgtgagt tgggagcatc tggcttatct tttgatacga
    14521 tcctagctag cggtatcaat tcttctaaac cccatgccca tccaatgcac aaaccagtgg
    14581 agttgggaga agccattacc atggacttcg gctgtctcta tgaccactat gtcagtgata
    14641 tgacccggac tatctatcta gggcatgtta gcgatgagca ggcagagatt tacaatacgg
    14701 ttctaaaagc taaccaagcc ttgattgacc aagctaaggc aggcttaggt ttccgtgact
    14761 ttgacaaaat ccctcgtgat attatcattg aggcaggtta tggtgactac tttactcacg
    14821 gcattggcca cggtattggt ctggatatcc atgaggaacc ctactttagt cagacttcta
    14881 cagaaactat taagacaggt atggccttga ccgatgaacc aggtatctat atcgaaggca
    14941 aatatggcgt tcgtatcgag gatgatatcc tgattacaga gacaggttgt gaattattga
    15001 ccctagctcc aaaagagttg atagtcattt agttgtttgt caagaaaaaa gtacgaaaat
    15061 gacgaaaaaa gtcaaaaaaa att
//
LOCUS       DAVBDR010000050        14869 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.050, whole genome shotgun sequence.
ACCESSION   DAVBDR010000050 DAVBDR010000000
VERSION     DAVBDR010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14869)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14869)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14869
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.050"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            complement(149..631)
                     /gene="greA"
                     /locus_tag="VQ540_001616"
     CDS             complement(149..631)
                     /gene="greA"
                     /locus_tag="VQ540_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018370745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HET2545390.1"
                     /translation="MAEKTYPMTLEEKEKLEKELEELKLVRRPEVVERIKIARSYGDL
                     SENSEYEAAKDEQAFVEGQISSLETKIRYAEIVNSDAVAQDEVAIGKTVTIQEIGEDE
                     EEVYIIVGSAGADAFAGKVSNESPIGQALIGKKTGDTATIETPVGSYDVKILKVEKTA
                     "
     gene            complement(702..2351)
                     /gene="mltG"
                     /locus_tag="VQ540_001617"
     CDS             complement(702..2351)
                     /gene="mltG"
                     /locus_tag="VQ540_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HET2545391.1"
                     /translation="MSEKSREEEKLSFKEQILRDLEKVKGYDEVLKEDEAVVRTPANE
                     PSAEELMTDSLSTVEEIMRKAPTVPTHPSQGVPASPADEIQRETPGVPSHPSQDVPSS
                     PAEESGSRPGPVRPKKLEREYNETPTRVAVSYTTAEKKAEQAGPETPTPATETVDIIS
                     DTSRRSRREGAKPVNPKKEKKSHVKAFVISFLVFLALLSAGGYFGYQYVLDSLLPIDA
                     NSKKYVTVGIPEGSNVQEIGTTLEKAGLVKHGLIFSFYAKYKNYTDLKAGYYNLQKSM
                     STEDLLKELQKGGTDEPQEPVLATLTIPEGYTLDQIAQAVGQLQGDFKESLTAEAFLA
                     KVQDETFISQAVAKYPTLLESLPVKDSGARYRLEGYLFPATYSIKESTTIESLIDEML
                     AAMDKNLSPYYSTIKSKNLTVNELLTIASLVEKEGAKTEDRKLIAGVFYNRLNRDMPL
                     QSNIAILYAQGKLGQNISLAEDVAIDTNIDSPYNVYKNVGLMPGPVDSPSLDAIESSI
                     NQTKSDNLYFVADVTEGKVYYANNQEDHDRNVAEHVNSKLN"
     gene            complement(2432..2926)
                     /locus_tag="VQ540_001618"
     CDS             complement(2432..2926)
                     /locus_tag="VQ540_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000702438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2545392.1"
                     /translation="MKIRQARLEDLDRIVELEFENFSVEEAIPPSVFEAHLREIQTSF
                     LVAEKEGRIMGYIEGPVGLHRHLQDQSFTEEIKDYSHEPGGYISVTCLSIAKEAQGLG
                     LGQKLLTALKEVALEDERDGINLTCHDYLIAYYEKHGFVNEGQSQSTFAGETWYDMVW
                     EMKK"
     gene            complement(2923..3387)
                     /locus_tag="VQ540_001619"
     CDS             complement(2923..3387)
                     /locus_tag="VQ540_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2545393.1"
                     /translation="MEIPIKIIQASKSDLPEIGALQTSSFPAEKQQLSHILEESIRKC
                     ADTFLLARDENQLLGYILSSPQSDNPQYLKVHSLVIESDHQRQGLGTLLLAALKEVAV
                     DLDYKGIRLESPDELLSYFEMNGFVDEEATLLYATSQGYSMIWFNPFYLEEQ"
     gene            complement(3397..4731)
                     /locus_tag="VQ540_001620"
     CDS             complement(3397..4731)
                     /locus_tag="VQ540_001620"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HET2545394.1"
                     /translation="MSKTYHFIGIKGSGMSALALMLHQMGHKVQGSDVEKYYFTQRGL
                     EQAGITILPFDEKNLDGDMEIIAGNAFRPDNNVEIAYADQNGISYKRYHEFLGSFMRD
                     FVSMGVAGAHGKTSTTGMLSHVLSHITDTSFLIGDGTGRGSANAKYFVFESDEYERHF
                     MPYHPEYSIITNIDFDHPDYFTSLEDVFNAFNDYAKQITKGLFVYGEDAELRKITSDA
                     PIYYYGFEAEGNDFVASDLLRSTTGSTFTVHFRGQNLGQFHIPTFGRHNIMNATAVIG
                     LLYTAGFDLNLVREHLKTFSGVKRRFTEKIVNDTVIIDDFAHHPTEIIATLDAARQKY
                     PSKEIVAVFQPHTFTRTIALLDDFAHALNQADAVYLAQIYGSAREVDHGDVKVEDLAN
                     KINKKHQVITVENVSPLLDHDNAVYVFMGAGDIQTYEYSFERLLSNLTSNVQ"
     gene            complement(4741..5358)
                     /locus_tag="VQ540_001621"
     CDS             complement(4741..5358)
                     /locus_tag="VQ540_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HET2545395.1"
                     /translation="MKQERFPLVSDDEVMLTEMPVMNLYDESDLISNIKGEYRDKNYL
                     EWAPIAEEKPVKPIEKQVGKPKKAPLGVKKEGKSYAEVAREEARADLKKKRSANYLTQ
                     DFSLARRHSQPSLVRQGNQPTTPFQKENPGEFVKYSQKLTQSHYILAEEVHSIPTKNE
                     EVSAPAPKKNNYDFLKKSQIYNKKSKQTEQERRVAQELNLTRMTE"
     gene            complement(5406..8504)
                     /locus_tag="VQ540_001622"
     CDS             complement(5406..8504)
                     /locus_tag="VQ540_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HET2545396.1"
                     /translation="MAKLIPGKIRIEGVALYETGKVDIIKEKNNRLYARVAEEELRYS
                     LEDDLVFCACDSFQKRGYCVHLAALEHFLKNDERGQEILWSLEEGHEEKEAVETKVTL
                     GGKFLNRILSPKSECAYELSAVGQVEAGTNHILWTLRIGQINSQKYYVIRDIPLFLRI
                     VEQRKSYMIGKIYEESLSWEAFDDASQELLTFLHGLTEEGLVPDLFFQNQGRHLFFPL
                     TFFEQGVNLLMALPHFQFDHQVDSYQTLLFQDMHADANLFAFTVTEYSDYFEMEISES
                     PRVNVFYQGAVLFHKGQVYFLTDQQMRLLKEIKALPVGQQGKKYLQFDSSDRDKLASC
                     LTLFIQMGTVSAPERLQIKTFAPSFYFDREEDNRIRLEIQFDYGNRQVSSRQELEELP
                     FSSDADLEERIFQVCLAAGFEADFQSWRQALKAESVYHFFHDIIPVFEKLGHVDLSDK
                     LEELYSLASPQVQIASKGGLLEIQFDFQNIAQEEIDQAMQALVANQDFYIDSSNQVYF
                     FDEETKKIRQNLQELGQFELKDGTLQARKSLAYSLAHLFEGRDRVSFSQEFQNLAQDL
                     THPEDFPLQATQVKADLRDYQEKGIGWLQMLHHYGFGGILADDMGLGKTLQTIAFLTS
                     QVTKESRVLILAPSGLIYNWADEFQKFAPQLDVAVVHGLKASREEILAESHQIYVTSY
                     ATFRQDSEFYQGMAFDFLFLDEAQVMKNAQTKIAQTLRQFVVPSVFALSGTPIENHLG
                     ELWSIFQIVMPGLLPSKKEFMKLPAERVAQFIKPFVMRRKKEEVLTELPDLIEVVYKN
                     ELEDQQKAIYLAQLQQMRDHLAQVSEQEFQRSRVEILSGLMRLRQICDTPALFMEDYQ
                     GASGKLDSLRDLLVQVADGGHRVLIFSQFKGMLEKIEQELPDLGLTSFKITGSTPAKE
                     RQDMTKAFNQGERDAFLISLKAGGVGLNLTGADTVILVDLWWNPAVEAQAIGRAHRMG
                     QEETVEVYRLVTKGTIEEKIQELQEQKKHLVSQVLDGTESRGSLTLAEIREILGISEA
                     ST"
     gene            complement(8597..9763)
                     /locus_tag="VQ540_001623"
     CDS             complement(8597..9763)
                     /locus_tag="VQ540_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HET2545397.1"
                     /translation="MGKYDFTSLPNRLGHHTYKWKETETDSEVLPAWIADMDFVVLPE
                     IRQAVQTYADQLVYGYTYASEDLIKEIQKWEATQYGYNFDKEALVFIEGVVPAISTAI
                     QTFTKEGEAVLINTPVYPPFARSVKLNNRRLITNSLVEKDGLFEIDFDQLEKDLVEEE
                     VKLYILCNPHNPGGRVWEKEVLEKIGQLCQKHGVLLVSDEIHQDLTLFGHKHQSFNTI
                     NPAFKNFAIVLSSATKTFNIAGTKNSYAVIENPKLRLAFQKRLLANNQHEISGLGYLA
                     TEAAYRYGKDWLEELKQVFEDHINYVVDLFGKETKIKVMKPQGTYLIWLDFSAYDLTD
                     ETLQELLRNEAKVILNRGLDFGEEGSLHARINIAMPKSLLQEVCQRIVATFAKR"
     gene            complement(9771..10865)
                     /locus_tag="VQ540_001624"
     CDS             complement(9771..10865)
                     /locus_tag="VQ540_001624"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HET2545398.1"
                     /translation="MSKELHINTILAQAGIKSDEATGALVTPLHFSTTYQHPEFGRST
                     GFDYTRTKNPTRSKAEEVLAAIESADYALATSSGMSAIVLAFSVFPVGSKVLAVRDLY
                     GGSFRWFNQVEQEGRFHFTYANTEEELIAELEKDVDVLYIETPTNPLMLEFDIEKLAK
                     LAHAKGAKVVVDNTFYSPIYQRPIEDGADIVLHSATKYLAGHNDVLAGVVVTNSLELY
                     EKLFYNLNTTGAVLSPFDSYQLLRGLKTLSLRMERSTANAQEVVAFLKDSPAVKEVLY
                     TGRGGMISFKVADETRIPHILNSLKVFSFAESLGGVESLITYPTTQTHADIPAEVRHS
                     YGLTDDLLRLSIGIEDARDLIADLRQALEG"
     gene            complement(11023..11675)
                     /locus_tag="VQ540_001625"
                     /pseudo
     CDS             complement(11023..11675)
                     /locus_tag="VQ540_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864981.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
     gene            complement(11700..12635)
                     /locus_tag="VQ540_001626"
     CDS             complement(11700..12635)
                     /locus_tag="VQ540_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2545399.1"
                     /translation="MKLKLLRVDTKVIMGSFLLVLSSLLALLLPLILKGLIDGSSIEN
                     IGSKVFQSFLIFIGQALFSSIGYYLFSQSGEKKIAKIRKKVIEGLIYAEKSFFDKSQS
                     GELTSAIVNDTSVIREFLITTFPNIILSLVMVLGSIVVLFSLDWNLSLLLFITLPCMM
                     FIILLLSNISEKYSRRLQEEIGFLTGQLTEKIQEHELIKTNQAEKSVQDVLDNCIERV
                     QNNSLKSDRVTSFETPFALLFIFATIAVMLTYGGYRVSAGYISVGTLVSFLIYLFQLL
                     NPISNIANFVTVYSRSKGSSVALENLLAVPKEKFE"
     gene            complement(12807..14765)
                     /locus_tag="VQ540_001627"
     CDS             complement(12807..14765)
                     /locus_tag="VQ540_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HET2545400.1"
                     /translation="MKKSKSKYLTLAGLVLGTGVLLSACGNSSTASKTYNYVYSSDPS
                     SLNYLAENRAATSDIVANLVDGLLENDQYGNIIPSLAEDWTVSQDGLTYTYKLRKDAK
                     WFTSEGEEYAPVTAQDFVTGLQYAADKKSEALYLVQDSVAGLDDYITGKTSDFSTVGV
                     KALDDQTVQYTLVKPELYWNSKTLATILFPVNADFLKSKGDDFGKADPSSILYNGPFL
                     MKALVSKSAIEYKKNPNYWDAKNVFVDDVKLTYYDGSDQESLERNFTAGAYTTARLFP
                     NSSSYEGIKEKYKNNIIYSMQNSTSYFFNFNLDRKSYNYTSKTSDIEKKSTQEAVLNK
                     NFRQAINFAFDRTSYGAQSEGKEGATKILRNLVVPPNFVSIKGKDFGEVVASKMVNYG
                     KEWQGINFADGQDPYYNPEKAKAKFAEAKKELEAKGVQFPIHLDKTVEVTDKVGIQGV
                     SSIKQSIESVLGSDNVVIDIQQLTSDEFDSSGYFAQTAAQKDYDLYHGGWGPDYQDPS
                     TYLDIFNTNSGGFLQNLGLEPGEANDKAKAVGLDVYTQMLEEANKEQDPAKRYEKYAD
                     IQAWLIDSSLVLPSVSRGGTPSLRRTVPFATAYGLTGTKGVESYKYLKVQDKIVTTDE
                     YAKAREKWLKEKEESNKKAQEELAKHVK"
BASE COUNT         4229 a         3325 c         2726 g         4589 t
ORIGIN      
        1 gttttgaggt tgtagatgaa actgacaaag tcagtaacca tacatacggc aaggcgacgc
       61 tgacgtggtt tgaagagatt ttcgaagaat agcaaaatgg aaaaaggagt gagtgaagca
      121 catcgcctcc ccactccttt ttctgttttt aggctgtttt ttcaaccttc aagattttta
      181 catcatagct accaacaggc gtttcaatgg ttgctgtgtc acctgttttc ttgccaatca
      241 aggcctgccc aattgggctt tcatttgaaa ccttacctgc aaaggcatcc gcaccagctg
      301 aacctacgat aatataaact tcttcttcgt cctcaccaat ttcttggatg gtgactgttt
      361 taccaatcgc tacttcgtcc tgggcaactg cgtcgctatt gacgatttca gcatagcgga
      421 tttttgtttc taagctagag atttgtcctt cgacaaaggc ttgttcatcc ttagctgctt
      481 cgtactcact gttttctgaa aggtcaccgt atgaacgggc aatcttaatg cgttctacca
      541 cttctggtcg acgaaccaat ttcaattctt ctaattcttt ttcaagtttt tccttttcct
      601 caagggtcat aggatatgtt ttttctgcca tttttctcaa ctttcttctg ataatatttt
      661 ctaaagaaaa ttatgtgacg tatcacataa ttttagtttg tttagtttaa tttgctgttg
      721 acatgttcag cgacattgcg gtcgtggtct tcttgattgt tagcatagta gaccttgcct
      781 tctgtgacat ctgctacaaa gtagaggtta tcgctcttag tttgattgat gcttgactca
      841 atcgcatcca gacttggact atcgactgga ccaggcatga gacctacatt tttataaaca
      901 ttataaggtg aatcaatgtt ggtatcaatc gcaacatcct cagctagact gatattttgc
      961 cccagttttc cttgggcata caagattgca atattacttt gaagtggcat atcacgattt
     1021 aaacgattgt agaatacacc tgcaatgagc ttacgatctt ctgtcttggc accttctttt
     1081 tcgaccaagg aagcaatggt caacaactca ttgacagtca aatttttaga tttgatagta
     1141 ctatagtaag gagataggtt cttatccata gcagctaaca tctcatcaat caagctctca
     1201 atagttgtgc tttccttgat agagtatgta gctgggaaaa ggtatccttc caaacgataa
     1261 cgcgcaccgc tgtcttttac aggcaaactt tccagtaaag taggatattt cgctactgct
     1321 tgactgataa acgtctcatc ttgaacttta gccaagaaag cctccgctgt caaagactct
     1381 ttgaagtcac cttgcaattg acccacagct tgagcaatct gatccaaggt ataaccttct
     1441 ggaattgtca aagtcgcaag tacaggttct tgcggttcat ctgttccacc tttttgcaac
     1501 tctttgagta agtcttctgt actcatactc ttttgcaaat tgtagtaacc tgctttcaag
     1561 tcggtataat ttttatactt ggcataaaaa ctaaaaatca gaccatgctt taccaaacca
     1621 gctttttcaa gcgtcgtacc gatttcttga acgtttgaac cttctggaat tccaaccgtc
     1681 acatatttct tagaattagc atcgataggt aacaaagaat ctagcacgta ctggtaacca
     1741 aagtaaccac ctgctgagag caaggcaagg aatacaagga atgaaatcac aaaagctttc
     1801 acatgtgact tcttctcttt cttaggatta acgggttttg ctccttctct acggctacga
     1861 cgtgatgtat cgctgatgat atccactgtt tctgtagcag gcgtaggtgt ttctggacct
     1921 gcttgttctg cttttttctc tgccgtcgta taggaaacag ctacccttgt tggggtttca
     1981 ttgtattctc tttcaagttt cttaggtcta acaggacctg gtcttgatcc actttcttcc
     2041 gctggagaag aaggtacatc ttgacttgga tgacttggaa caccaggagt ttctctttga
     2101 atctcatctg ctggagaagc tggtacacct tgacttgggt gagtaggcac ggtaggagct
     2161 tttctcataa tctcctctac cgttgacaag gaatcagtca tgagttcttc agctgaaggt
     2221 tcatttgcag gagtgcgaac tactgcctca tcttctttca gaacttcatc atagcctttt
     2281 actttttcta aatctctcag aatctgctct ttaaagctta atttctcttc ttctcttgac
     2341 ttttcactca aaagtttttc ctccttgttg ataatccata atattatatc ttaaaagtcc
     2401 aaaaaaagca atctatgata cttttcctaa cttatttttt catttcccag accatatcat
     2461 accatgtttc ccctgcaaag gttgactggg actggccttc gttgacaaat ccatgttttt
     2521 cataataggc gatgagatag tcatgacagg ttagattaat gccatctctc tcatcttcaa
     2581 gagcaacttc tttcaaagct gtcagcaatt tctgacccag tccgagtccc tgtgcctcct
     2641 tggcaataga cagacaggtc acagagatat aaccaccagg ctcatgacta tagtctttta
     2701 tttcttctgt aaaagactgg tcttgcagat ggcggtgcag gccaactggt ccttcgatat
     2761 aacccatgat tcttccttct ttttcagcaa ccagaaaaga ggtctgaatt tctctcaaat
     2821 gtgcttcaaa gacagaagga ggaatggctt cttcgaccga aaaattttca aattcaagtt
     2881 caacaatccg atccaaatct tctaatcttg cttgtctgat tttcattgtt cctccagata
     2941 aaagggatta aaccaaatca tactatagcc ctggctagtt gcatagagca aagttgcttc
     3001 ttcatcaaca aaaccgttca tttcaaaata ggaaagcagc tcatcaggac tctccaaacg
     3061 aatccctttg taatccagat caactgccac ctctttcaag gctgcaagaa gaagtgttcc
     3121 caagccctgt ctctgatggt cagactcgat gactaaagaa tgtactttta gatattgcgg
     3181 attgtctgac tggggacttg ataaaatata gcctaaaagt tgattttcat ccctagctag
     3241 aagaaaggta tccgcacact tacggatact ttcttctaaa atatgggaaa gttgctgctt
     3301 ttcagctgga aaagacgagg tctgaagtgc ccctatctca ggcaaatcag acttgcttgc
     3361 ctgaatgatc ttaattggaa tttccatggg aacatcctat tgaacattgc ttgtcaagtt
     3421 agacaagaga cgctcaaatg agtattcata ggtttggatg tctcctgctc ccataaagac
     3481 gtaaacagca ttgtcatggt ctaggagcgg agaaacattt tcaacagtaa tcacttggtg
     3541 ttttttgttg attttgttgg ctaggtcttc taccttaacg tcaccatgat ctacttcacg
     3601 agccgagcca taaatttgcg ctagataaac agcatctgct tggtttaaag catgggcaaa
     3661 gtcgtccaac aaggcaatgg ttcttgtaaa ggtatgcggt tgaaagactg ctacaatttc
     3721 cttgcttggg tatttctgac gagccgcatc caaggtcgca ataatttctg ttggatgatg
     3781 ggcaaagtca tcgataatca ctgtatcatt gacaattttc tcagtgaaac gacgtttaac
     3841 accggaaaat gttttcaagt gctcacgcac caagttcaaa tcaaatcctg ctgtgtaaag
     3901 aagaccaata acggctgtcg cattcatgat attgtgacga ccaaaggttg gaatgtggaa
     3961 ttgccccaag ttttgtccac ggaaatgaac ggtgaaggtt gaaccagttg ttgaacgaag
     4021 aagatcacta gctacaaagt cattgccttc agcttcaaaa ccataataat aaattggtgc
     4081 atcagacgta atcttacgca attcagcatc ttcaccatag acaaaaagac ccttggtgat
     4141 ttgtttggca tagtcgttaa aggcattgaa aacatcctcg agacttgtga aataatctgg
     4201 atggtcaaag tcaatgttgg tgataataga gtattctggg tggtaaggca tgaagtgacg
     4261 ctcatattcg tcagattcaa agacaaaata tttggcattg gccgaaccac gacctgtccc
     4321 atctccaatc aagaagctgg tatctgtaat gtgagacaag acatgagaca acatacctgt
     4381 cgttgaagtt tttccatgtg ctcctgctac tcccatgcta acaaagtcac gcataaagct
     4441 acctagaaac tcatggtaac gtttgtagct gataccattt tggtccgcat aggcaatttc
     4501 gacgttgtta tctggacgaa aggcatttcc agcgataatt tccatatcac cgtctagatt
     4561 cttttcatca aaaggaagaa tggtaattcc tgcctgctca agaccgcgtt gggtaaagta
     4621 gtacttttca acatctgatc cctgaacctt gtgccccatc tggtgcaaca tcaaggccaa
     4681 ggcactcatc cctgatccct taattccgat aaaatgatat gtctttgaca tgttttctcc
     4741 ctattctgtc attctggtca gattcaactc ttgggcaacc cgacgttctt gttctgtttg
     4801 tttacttttt ttattgtaga tttggctctt ctttagaaaa tcataattgt ttttctttgg
     4861 agcaggtgct gacacttctt cattcttggt agggatagaa tgaacttctt ccgccaagat
     4921 ataatgagac tgggtcaatt tttggctata tttgacaaat tcaccaggat tttccttttg
     4981 gaaaggagtt gtcggttgat tgccctgtct aactagactg ggctgagaat gacgtctcgc
     5041 aaggctgaaa tcctgagtta gatagttagc agagcgtttc tttttcaagt ctgcacgcgc
     5101 ttcttcacgc gccacctccg catagctctt tccttctttt ttaaccccta aaggagcttt
     5161 tttaggtttc cctacttgct tttcaatcgg ttttactggt ttttcttcag caataggagc
     5221 ccattctaaa taatttttat ctcgatactc acccttgata ttactgatca gatcagactc
     5281 atcatagaga ttcatgactg gcatttcagt caacatgacc tcgtcatctg acaccaatgg
     5341 aaatcgttct tgtttcattt tctatttcct ttcaacactt cattatagcg tattgtcttg
     5401 atttttcaag tgctggcttc agaaattccc aaaatttctc taatttctgc tagggtcaga
     5461 ctaccacgtg actctgtgcc gtccaatact tgtgacacca gatgtttctt ttgttcttgg
     5521 agttcctgaa ttttttcttc aatggttccc ttggtcacca agcgatagac ctcaaccgtt
     5581 tcttcctgac ccatccgatg ggcacggcca atggcttgcg cttccaccgc aggattccac
     5641 caaaggtcaa ccaagatcac tgtatctgca cctgtcaggt tcagaccgac cccaccagcc
     5701 ttgagggaaa tcagaaaggc atctctttct ccttgattaa aggccttggt catgtcttgt
     5761 ctttccttgg ctggggttga acccgtaatt ttaaaggaag tcaggcccaa gtctggcagt
     5821 tcttgttcaa ttttttccaa cattcccttg aactgagaga aaatcaagac acggtgtccg
     5881 ccgtctgcca cctgtaccag taggtctcgg agactatcta gtttgccgct ggctccctga
     5941 taatcttcca taaacagggc aggagtgtca catatttgac gcaagcgcat caaaccagat
     6001 aaaatttcca cacgacttcg ctgaaattcc tgttctgaca cttgagccag atggtctcgc
     6061 atctgttgta actgggcaag gtaaatagcc ttttgctggt cttccagttc atttttataa
     6121 accacctcaa tcaagtctgg caattcagtc agaacttctt ctttcttgcg tcgcatcacg
     6181 aaaggcttga taaactgagc cactcgctct gctggcaatt tcataaattc tttcttgctt
     6241 ggcaaaagtc cgggcatgac gatttggaaa atagaccaca actcacccag atggttttca
     6301 atcggagttc ctgacaaggc aaagaccgac ggcaccacaa attgtctcaa ggtctgggca
     6361 atcttggtct gggcattttt catgacctga gcctcatcta agaaaaggaa gtcaaaggcc
     6421 atcccctgat aaaactcact gtcctgacgg aaggtggcat agctagtcac atagatttga
     6481 tggctctcgg caagaatctc ctcacgactt gctttcaaac catgaacaac agccacatcc
     6541 aactgtgggg caaatttctg aaactcatcc gcccagttgt aaatcaaacc cgacggagcg
     6601 agaatcaaga ctcgactttc ttttgtcact tgactagtca aaaaagcaat ggtctgaagg
     6661 gttttcccaa gtcccatatc atcagccaaa atcccaccaa aaccataatg atggagcatc
     6721 tgcaaccagc caattccctt ttcctgataa tctcgcaagt cagccttgac ctgagttgct
     6781 tgcaaaggaa agtcctctgg atgcgtcaaa tcctgggcca gattctggaa ttcttgtgaa
     6841 aaagaaacac ggtctcgccc ttcaaagaga tgagctaaac tgtaggccaa ggatttccga
     6901 gcctgcaagg tcccatcttt taattcaaat tgccccagtt cctgtagatt ttggcgaatt
     6961 ttcttggttt cttcatcgaa aaagtaaact tgattagacg aatcaatata aaaatcctga
     7021 ttggcaacca aggcctgcat ggcttggtcg atttcctcct gggcaatatt ttgaaaatca
     7081 aactggattt ccaagagacc tcccttggag gcaatctgca cctgaggact cgctaggcta
     7141 taaagctctt ctagtttatc tgataggtca acatgcccga gtttttcaaa gactggaatg
     7201 atatcatgaa aaaaatgata gacagactcc gcttttaagg cctgacgcca agattgaaaa
     7261 tcggcttcaa agcccgcagc caaacagact tggaaaattc tttcttctaa gtccgcgtca
     7321 cttgaaaatg gtaattcttc tagctcttgt cggctagata cctgtctatt tccataatca
     7381 aactgaattt ctaaacgaat ccgattatct tcttccctgt caaagtaaaa agagggcgca
     7441 aaagttttga tttgtagacg ttctggagct gaaacggtgc ccatctggat aaaaagagtc
     7501 agacaggagg ccaatttgtc tcgatcactg ctatcaaatt gcaggtattt ctttccttgt
     7561 tgacccacag gtaacgcttt aatttccttg agaagacgca tctgctggtc tgttaaaaaa
     7621 taaacctgac ctttatggaa aagtactgct ccctgataaa agacattgac cctaggactc
     7681 tcactgattt ccatttcaaa atagtccgag tattctgtta ctgtaaaggc aaatagattg
     7741 gcatcagcat gcatatcctg aaaaagcagg gtttggtagc tatccacttg atggtcaaat
     7801 tgaaaatggg gcaaggccat cagtaaattc acaccctgct caaaaaaggt cagagggaaa
     7861 aagaggtgcc gaccttggtt ttggaaaaag aggtctggaa ccagcccttc ctccgttagt
     7921 ccgtgcaaga aagtcaaaag ttcttggctg gcatcatcaa aggcttccca agaaagagac
     7981 tcctcataaa tcttgccaat catatacgac tttctctgct cgacaatcct taaaaaaagt
     8041 ggaatatccc gaatgacata gtatttttgg ctattgattt ggccgattct cagagtccac
     8101 aagatatgat tggttcctgc ttccacctga cccacagctg ataactcata ggcgcattct
     8161 gattttggag ataaaattcg attcaaaaac ttgccaccca aggtcacctt ggtttcaacg
     8221 gcctcttttt cttcatgacc ttcttccaga ctccacaaga tttcctgacc acgctcatca
     8281 tttttcagaa aatgctctag cgctgccaaa tgcacacagt agcccctctt ttgaaaagaa
     8341 tcacaggcac aaaaaaccaa atcatcctct aaactatagc gcagttcttc ttctgcaacg
     8401 cgagcgtaga gccgattgtt cttttccttg atgatatcaa ccttaccagt ttcataaagg
     8461 gcaacacctt cgatacgaat tttccccgga atcaatttag ccatattttc acctttacct
     8521 tatcttttta ttataccata ttttcgccta tgaaaatagc cttctaggaa gacttttctc
     8581 ctagaaggct ggatttttaa cgtttggcaa aagtagccac aatccgctga cagacttctt
     8641 gcaacagaga tttgggcata gctatattga tgcgggcatg gagacttcct tcctctccaa
     8701 aatccaaacc acggttgagg ataaccttgg cttcatttct caacaactct tgcaatgttt
     8761 catcagtcag gtcataggct gaaaagtcaa gccaaatcaa gtaggtacct tgcggtttca
     8821 tgaccttgat tttagtctct tttccaaata gatccaccac ataattgatg tggtcttcaa
     8881 agacttgctt gagttcctct agccaatctt taccgtatcg ataggcagct tctgtcgcca
     8941 aataacccaa gcctgaaatt tcatgctgat tattggccaa caggcgtttc tggaaagcca
     9001 gtctcaactt aggattttca atgactgcat aggaattttt tgttccagca atattaaatg
     9061 ttttagtggc actgctcaag acgatagcaa aatttttgaa ggcaggattg atggtattga
     9121 aagactggtg tttgtgacca aagagggtca aatcttggtg aatctcatcc gaaactaaca
     9181 aaacaccgtg tttttggcaa agttggccaa tcttctccaa cacttctttt tcccaaacac
     9241 gtccaccagg attgtgaggg ttgcaaagaa tatagagttt aacctcctct tccaccaaat
     9301 ccttttcaag ttggtcaaag tcaatctcaa acagaccatc cttttccact aaggaattag
     9361 taatcaatct acgattattc aacttgacac tgcgagcaaa gggtgggtag acaggcgtgt
     9421 taattaaaac cgcctcgcct tcttttgtaa aggtttgaat agctgttgag atggctggta
     9481 ccacaccctc gataaagaca agagcctctt tgtcaaagtt gtaaccgtat tgtgtagctt
     9541 cccacttttg aatttcctta attaagtctt cactggcata ggtataacca taaaccagtt
     9601 ggtctgcgta agtttgcacg gcttggcgga tttcaggcaa gaccacaaag tccatatccg
     9661 ctatccaagc tggtagaact tcactatccg tttctgtttc tttccattta taggtatggt
     9721 gccctaaacg gttgggcagg cttgtaaaat catattttcc catctttgtc ttatccttct
     9781 aaggcttggc gcaaatctgc aatcaaatct ctagcatcct caatcccaat agacaaacgc
     9841 aagaggtcat ctgtcaaacc ataagaatgg cgtacttctg ctggaatatc agcatgagtt
     9901 tgagtcgttg gataagtaat aagactttcc actccgccca aactttccgc aaaagagaag
     9961 accttgagac tgttcaaaat atgaggaatg cgtgtttcat cggctacttt aaaggaaatc
    10021 atgcctccac gaccagtgta gagaacttcc ttaactgctg gagaatcctt caaaaaggca
    10081 accacttctt gggcgttagc tgttgagcgc tccatacgaa gagataaggt cttgagacca
    10141 cgaagcaact ggtagctgtc aaatggagac aagactgccc ctgttgtatt gagattgtaa
    10201 aaaagcttct cgtatagttc taaactattg gtcacaacca ctccagccaa gacatcattg
    10261 tggcctgcta gatacttggt tgctgaatgg agaacgatat ctgctccatc ttcaatcgga
    10321 cgttggtaga tagggctata gaaggtattg tccaccacca ctttggcacc cttagcatga
    10381 gccaattttg ctagtttttc gatatcaaat tccaacatca agggattggt tggggtttcg
    10441 atatagagaa catccacatc cttttctaac tcggcaatca actcttcttc tgtattggca
    10501 taggtaaaat ggaaacgacc ttcctgctcc acttggttaa accagcgaaa agaaccaccg
    10561 taaagatcac gcactgccaa gaccttactt cctactggaa agacgctaaa ggccagtaca
    10621 atagctgaca tccctgagct agtcgctagg gcatagtctg ctgactcaat agccgccaag
    10681 acttcctcag ccttactacg agttggattt ttagtgcgcg tatagtcaaa cccagtagat
    10741 cgaccaaact ctggatgctg ataggtcgtt gaaaaatgaa gcggtgtcac caatgcacct
    10801 gtcgcttcat ctgacttaat acccgcctgg gccaaaattg tgttaatgtg taattccttg
    10861 ctcatacaat acctccaaat ctatagtaac tattgtacca cttattttca tcaactcatt
    10921 ttcttctttt caagagctag ttatagtttc aaactatata aaaagggagt ttttcctgct
    10981 ccctttaata gactataaaa tggtgaatct caaaagacac cttcactcta tcatttgctc
    11041 ctgcacaaaa cgagcataac gctcatgatt ttccagtagt tccttatgag ttcctgagcc
    11101 agtgattttc ccctcctcta agaagaaaat acaatccaca tcttttaccg ttgacaaacg
    11161 atgcgctata atcacaaccg tcttctcctt taatacagaa tagaggctac tgataatcgc
    11221 atactcagaa tccgcatcaa gattagcagt ggcttcatca aatataagaa tttcagcatc
    11281 ttttaagtag gctctagcta tttgaagtct ttggctttgc ccccctgaca agagtcgtcc
    11341 gcgttcacca acttcagtat ctagtccctc tttcatggag cgaatctcat cacctagtga
    11401 tactaagtct agcactttca tcaattcatc atcagttact aagcgatttt acttctccat
    11461 tcttttaagt taaaatcata tatacttgat tgctccatta gaatatctcc tgaaagcggt
    11521 ttataaaacc gctctaacaa acgcacaatc gttgattttc ctgatccaga tggtccaaca
    11581 aaagcaattt tttgcccctt gaaaattgaa caagtaatat cctttaagac aggtcgattt
    11641 tcatcataac caaaatagac atggttaaaa ttcaaccctt gtcctgatac cgattttcct
    11701 cactcaaatt tttctttagg aactgcaagc aagttctcca gtgcaactga agatcccttg
    11761 ctcctagaat aaacagttac aaaattagct atattactaa taggattaag taattgaaag
    11821 aggtaaatca aaaacgaaac caaggttccc acagatatat atcctgcgct gacccgataa
    11881 cccccatagg ttagcatcac agctatagtc gcaaagataa ataagagagc aaacggggtc
    11941 tcaaaagaag taaccctatc tgatttcagt gaattgtttt gtaccctttc aatacaatta
    12001 tccaaaacat cctgtacact tttctctgct tggttagtct taattaattc atgttcttga
    12061 atcttttcag tcaattgccc tgttaaaaat ccgatttcct cctgtaaacg acgactatac
    12121 ttttcactga tattggaaag gagcaagata ataaacatca tacaaggaag agtgatgaat
    12181 aaaagtagag aaagattcca atcaagacta aataagacta caatggaacc aagtaccata
    12241 actaaactca gaataatatt tgggaaagtc gtaattaaaa actcacgaat gacactcgtg
    12301 tcattgacaa tggcagaagt caactcccca ctttggctct tatcaaagaa ggatttctct
    12361 gcataaatca acccctctat cacttttttc ctgatttttg ctatcttttt ttcacccgat
    12421 tgactaaaca gatagtaacc aatagaagaa aacaaggctt gaccaataaa aatcaaaaac
    12481 gattgaaata ctttggaacc tatattttca atagaactcc catctattaa accctttaag
    12541 ataaggggaa gcaacaaagc aagtagacta gacagaacaa gtaagaaact ccccataatc
    12601 accttagtat ctactcttaa taattttaat ttcataaata ctccttataa tatttcaacg
    12661 gataaagtcg ggaataactc aatttgagga taaaatctaa taaatcttcc tataacaaaa
    12721 cgcataacat ctaggatttt atatacctga tattatgcgt ttttaagcac aaagacttct
    12781 tacacaaact tatctacaat tagattttat ttgacatgtt ttgccaattc ttcttgggct
    12841 tttttattgg attcttcttt ttctttcaac catttttctc tggcttttgc atattcgtct
    12901 gttgtgacaa tcttatcttg tactttgagg tatttatatg attcaacccc ttttgtaccg
    12961 gttaaaccat aggcagtagc aaatggtacg gttcttctca atgatggtgt tcccccacgc
    13021 gaaacacttg gaagaactaa agaactatca atcaaccaag cttgaatatc agcatatttc
    13081 tcataacgtt tggctggatc ttgctcttta ttagcttctt ccaacatttg agtatagaca
    13141 tccagtccaa ctgccttagc cttgtcattg gcctcaccag gctctagtcc aagattttgc
    13201 agaaatcctc cactattagt attaaaaata tcgagatagg ttgacgggtc ttgataatca
    13261 ggtccccaac cgccatgata taaatcatag tctttctgag cagctgtttg agcaaagtag
    13321 cctgaactgt caaactcatc tgatgttaat tgctgaatgt caatcactac attatcagaa
    13381 cctaaaacag attcaattga ttgtttgata gaactaactc cttgtatgcc tactttatct
    13441 gttacttcca cagtcttatc caagtggatt gggaattgaa caccctttgc ttcgagttct
    13501 ttcttagctt ccgcaaactt agccttggct ttctcaggat tgtagtaagg gtcttgacca
    13561 tccgcaaagt tgataccttg ccattcctta ccatagttga ccatcttaga ggctacaact
    13621 tcaccaaagt cttttccctt gatactgaca aagtttggag gaaccactag gttacgcaaa
    13681 atctttgttg caccttcttt cccttcagac tgagccccat aagatgttct gtcaaaagca
    13741 aaattgatag cctgacggaa gtttttattg agaactgctt cctgagtcga tttcttttca
    13801 atgtcacttg ttttagaagt ataattgtaa gacttcctat ctaggttaaa attaaagaaa
    13861 tatgaagttg aattttgcat actatagatg atattgtttt tgtatttttc tttaatccct
    13921 tcatagctgg agctgttagg aaaaagacga gccgtagtat aagcaccagc tgtaaaatta
    13981 cgttccagtg attcttggtc gctaccatca tagtaggtca atttcacatc gtctacaaag
    14041 acattcttag catcccagta attagggttt ttcttatatt caatagcaga ttttgagaca
    14101 agtgctttca tcaagaaagg tccattgtac aaaatactag atggatccgc cttcccaaaa
    14161 tcatcccctt ttgatttcag gaaatctgca ttaacaggaa aaagtatcgt tgcaagtgtt
    14221 tttgaattcc agtaaagttc tggtttaacc aaagtatatt gaaccgtttg gtcatcaagt
    14281 gccttgacac cgacagttga aaagtcgctt gttttaccag tgatatagtc atccaaacca
    14341 gcaacagagt cctgcactag atacaaggct tctgattttt tatcagctgc atattgcaaa
    14401 cctgtcacaa aatcctgggc agttacaggc gcatattctt ctccctcaga agtaaaccac
    14461 ttggcatcct tacgaagttt gtaggtatag gtcaaaccgt cctgagaaac agtccaatcc
    14521 tctgctaatg atggaataat attcccatat tggtcatttt ctaataaccc gtctaccaaa
    14581 tttgcaacaa tatcggatgt tgctgcgcgg ttttctgcta gatagttcaa gctagatgga
    14641 tcacttgaat aaacatagtt gtatgttttt gacgccgtgc tagaatttcc acacgcgctc
    14701 aataaaactc ctgtacccag gacaagacct gccaaggtta gatatttgct cttagacttt
    14761 ttcatttccg gaacctcctg ctttaaatat ttgttttatt atacaacgtt tagtttgttt
    14821 agtcaatgat tttttccaaa aaatcgaaaa aagcctcatt ttctatttt
//
LOCUS       DAVBDR010000051        14294 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.051, whole genome shotgun sequence.
ACCESSION   DAVBDR010000051 DAVBDR010000000
VERSION     DAVBDR010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14294)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14294)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14294
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.051"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            complement(159..1085)
                     /locus_tag="VQ540_001628"
     CDS             complement(159..1085)
                     /locus_tag="VQ540_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2545401.1"
                     /translation="MISRFFRHLFEALKSLKRNGWMTVAAVSSVMITLTLVAIFASVI
                     FNTAKLATDIENNVRVVVYIRKDVEDNSQTIEKEGQTVTNNDYHKVYDSLKNMSTVKS
                     VTFSSKEEQYEKLTEIMGDNWKIFEGDANPLYDAYIVEANTPNDVKTIAEDAKKIEGV
                     SEVQDGGANTERLFKLASFIRVWGLGIAALLIFIAVFLISNTIRITIISRSREIQIMR
                     LVGAKNSYIRGPFLLEGAFIGLLGAIAPSVLVFIVYQIVYQSVNKSLVGQNLSMISPD
                     LFSPLMIALLFVIGVFIGSLGSGISMRRFLKI"
     gene            complement(1078..1770)
                     /gene="ftsE"
                     /locus_tag="VQ540_001629"
     CDS             complement(1078..1770)
                     /gene="ftsE"
                     /locus_tag="VQ540_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HET2545402.1"
                     /translation="MSIIEMRDVVKKYDNGTTALRGVSVSVQPGEFAYIVGPSGAGKS
                     TFIRSLYREVKIDKGSLSVAGFNLVKIKKKDVPLLRRSVGVVFQDYKLLPKKTVYENI
                     AYAMEVIGENRRNIKRRVMEVLDLVGLKHKVRSFPNELSGGEQQRIAIARAIVNNPKV
                     LIADEPTGNLDPDNSWEIMNLLERINLQGTTILMATHNSQIVNTLRHRVIAIENGRVV
                     RDESKGEYGYDD"
     gene            complement(1788..2883)
                     /gene="prfB"
                     /locus_tag="VQ540_001630"
     CDS             complement(join(1788..2810,2812..2883))
                     /gene="prfB"
                     /locus_tag="VQ540_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511312.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HET2545403.1"
                     /translation="MDISVIRQKIDANREKLASFRGSLDLEGLEEEIAILENKMTEPD
                     FWNDNIAAQKTSQELNELKNTYNTFHKMEELQDEVEILLDFLAEDESVHDELVAQLAE
                     LDKIMTSYEMTLLLSEPYDHNNAILEIHPGSGGTEAQDWGDMLLRMYTRYGNAKGFKV
                     EVLDYQAGDEAGIKSVTLSFEGPNAYGLLKSEMGVHRLVRISPFDSAKRRHTSFTSVE
                     VMPELDDTIEVEIREDDIKMDTFRSGGAGGQNVNKVSTGVRLTHIPTGIVVQSTVDRT
                     QYGNRDRAMKMLQAKLYQMEQDKKAAEVDSLKGEKKEITWGSQIRSYVFTPYTMVKDH
                     RTSFEVAQVDKVMDGDLDGFIDAYLKWRIS"
     gene            complement(2991..3647)
                     /locus_tag="VQ540_001631"
     CDS             complement(2991..3647)
                     /locus_tag="VQ540_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HET2545404.1"
                     /translation="MAVKDFMTRKVVYISPDTTVSHAADLMREQGLHRLPVIENDQLV
                     GLVTEGTIAQASPSKATSLSIYEMNYLLNKTKVKDVMIRDVVTVSGYASLEDATYLML
                     KNKIGILPVVDNHQVYGVITDRDVFQAFLEIAGYGEEGIRVRFVTEDEVGVLGKIVSL
                     IVEENLNISHTVNIPRKDGKVIIEVQIDESIDLPALREKFEANGIQVEEIARTSAKVL
                     "
     gene            complement(4112..4822)
                     /locus_tag="VQ540_001632"
     CDS             complement(4112..4822)
                     /locus_tag="VQ540_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000062217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2545405.1"
                     /translation="MSMLKVENLSVHYGMIQAVRDVSFEVNEGEVVSLIGANGAGKTT
                     ILRTLSGLVRPSSGKIEFLGQEIQKIPAQKIVAGGLSQVPEGRHVFPGLTVMENLEMG
                     AFLKKNREENQANLKKVFSRFPRLEERKNQDAATLSGGEQQMLAMGRALMSTPKLLLL
                     DEPSMGLAPIFIQEIFDIIQDIQKQGTTVLLIEQNANKALAISDRGYVLETGKIVLSG
                     TGKELASSEEVRKAYLGG"
     gene            complement(4822..5586)
                     /locus_tag="VQ540_001633"
     CDS             complement(4822..5586)
                     /locus_tag="VQ540_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002913097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2545406.1"
                     /translation="MALLEVKQLTKHFGGLTAVGDVTLELNEGELVGLIGPNGAGKTT
                     LFNLLTGVYEPSEGTVTLDGHLLNGKSPYKIASLGLGRTFQNIRLFKDLTVLDNVLIA
                     FGNHHKQHVFTSFLRLPAFYKSEKELKAKALELLKIFDLDGDAETLAKNLSYGQQRRL
                     EIVRALATEPKILFLDEPAAGMNPQETAELTELIRRIKDEFKITIMLIEHDMNLVMEV
                     TERIYVLEYGRLIAQGTPDEIKTNKRVIEAYLGGEA"
     gene            complement(5586..6542)
                     /locus_tag="VQ540_001634"
     CDS             complement(5586..6542)
                     /locus_tag="VQ540_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HET2545407.1"
                     /translation="MKENLKVNILWLLLLLAGYSLISVLVSVGVLNLFYVQILQQIGI
                     NIILAVGLNLIVGFSGQFSLGHAGFMAIGAYAAAIIGSKLPTYGAFFGAMLVGALLSG
                     AVALLVGIPTLRLKGDYLAVATLGVSEIIRIFIINGGSLTNGAAGILGIPNFTTWQMV
                     YFFVVITTIATLNFLRSPIGRSTLSVREDEIAAESVGVNTTKIKIIAFVFGAITASIA
                     GSLQAGFIGSVVPKDYTFINSINVLIIVVFGGLGSITGAIVSAIVLGILNMLLQDVAS
                     VRMIIYALALVLVMIFRPGGLLGTWELSLSRFFKKSKKEEQN"
     gene            complement(6546..7415)
                     /locus_tag="VQ540_001635"
     CDS             complement(6546..7415)
                     /locus_tag="VQ540_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HET2545408.1"
                     /translation="MLQQLVNGLILGSVYALLALGYTMVYGIIKLINFAHGDIYMMGA
                     FIGYFLINSFQMNFFVALIVAMLATAILGVVIEFLAYRPLRHSTRIAVLITAIGVSFL
                     LEYGMVYLVGANTRAFPQAIQTVRYDLGPISLTNVQLMILAISLILMILLQVIVQKTK
                     MGKAMRAVSVDSDAAQLMGINVNRTISFTFALGSALAGAAGVLIALYYNSLEPLMGVT
                     PGLKSFVAAVLGGIGIIPGAALGGFVIGLLETFATAFGMSDFRDAIVYGILLLILIVR
                     PAGILGKNVKEKV"
     gene            complement(7683..8843)
                     /locus_tag="VQ540_001636"
     CDS             complement(7683..8843)
                     /locus_tag="VQ540_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HET2545409.1"
                     /translation="MKKKFALSFVALASVALLAACVEVKSGAVNTAGNSVEEKTIKIG
                     FNFEESGSLAAYGTAEQKGAQLAVDEINAAGGIDGKQIEVVDKDNKSETAEAASVTTN
                     LVTQSKVSAVVGPATSGATAAAVANATKAGVPLISPSATQDGLTKGQDYLFIGTFQDS
                     FQGKIISNYVSEKLNAKKVVLYTDNASDYAKGIAKSFRESYKGEIVADETFVAGDTDF
                     QAALTNMKGKDFDAIVVPGYYNEAGKIVNQARGMGIDKPIVGGDGFNGEEFVQQATAE
                     KASNIYFISGFSTTVEVSAKAKAFLDAYRAKYNEEPSTFAALAYDSVHLVANAAKGAK
                     NSGEIKDNLAKTKDFEGVTGQTSFDADHNTVKTAYMMTMNNGKVEAAEVVKP"
     gene            complement(8944..9192)
                     /locus_tag="VQ540_001637"
     CDS             complement(8944..9192)
                     /locus_tag="VQ540_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HET2545410.1"
                     /translation="MFEKVNRSGLIIYLYYNRDAKKLQDYGDITYHSKKHRYLQLYVP
                     TQEVEQLVGRLSKEKFIKKVRVCHIQELETPFVGNLYR"
     gene            complement(9271..9861)
                     /gene="clpP"
                     /locus_tag="VQ540_001638"
     CDS             complement(9271..9861)
                     /gene="clpP"
                     /locus_tag="VQ540_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease proteolytic subunit
                     ClpP"
                     /protein_id="HET2545411.1"
                     /translation="MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIA
                     QLLFLDAQDSTKDIYLYVNTPGGSVSAGLAIVDTMNFIKADVQTIVMGMAASMGTVIA
                     SSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNTLEKILAENSGQ
                     SMEKVHADAERDNWMSAQETLEYGFIDEIMANNSLN"
     gene            complement(10035..10664)
                     /gene="upp"
                     /locus_tag="VQ540_001639"
     CDS             complement(10035..10664)
                     /gene="upp"
                     /locus_tag="VQ540_001639"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002883819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HET2545412.1"
                     /translation="MGKIEVINHPLIQHKLSILRRTDTSTKAFRELVDEIAMLMGYEV
                     LRDLPLEDVEIETPITKTVQKQLAGKKLAIVPILRAGIGMVDGLLSLVPAAKVGHIGM
                     YRDEETFQPVEYLVKLPEDIDQRQIFVVDPMLATGGSAILAVDSLKKRGASNIKFVCL
                     VSAPEGVKALQEAHPDVEIFTAALDERLNEHGYIVPGLGDAGDRLFGTK"
     gene            complement(10753..11220)
                     /locus_tag="VQ540_001640"
     CDS             complement(10753..11220)
                     /locus_tag="VQ540_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000138511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine/deoxycytidylate deaminase family
                     protein"
                     /protein_id="HET2545413.1"
                     /translation="MTEKRLAWDEYFAAQALLIANRSTCKRAKVGAILVKDNKVISTG
                     YNGSVSGTEHCIDHECLVIEGHCVRTLHAEVNAILQGAERGVPKGFTAYVTHFPCLNC
                     TKQLLQVGCKRVVYINQYRMDDYAQYLYQEKGTELTHLPLETVQTALKEADLM"
     gene            complement(11239..11796)
                     /locus_tag="VQ540_001641"
     CDS             complement(11239..11796)
                     /locus_tag="VQ540_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HET2545414.1"
                     /translation="MSERRISEKSLENLRKSNQESNLLTREAIETALLQLLEKKELTK
                     ISISELVKRAGVSRAAFYRNYDSKEEILESVFKRTVHNIMEQLHHYDLKTDLYLVWVH
                     LFREARKEARVIQLALDYHLEKIFVQAMQEFLEKYHGKSKGVSSYLHSFWSSAIVSVL
                     LKWIKDGMKVPAEKIADLGLPFFKK"
     gene            11921..12766
                     /locus_tag="VQ540_001642"
     CDS             11921..12766
                     /locus_tag="VQ540_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HET2545415.1"
                     /translation="MTWKIIADSGCDYRQLPTPAINTTFVSVPLTIQVADQVFVDDAS
                     LDIDQMMETMYATAEASKSACPSPDDYLRAFEGAKNIFLVTITGTLSGSHNSAQLAKN
                     IYLEDHPDTKIHVIDSLSAGGEVDLLVEKLNDLIDQGLSFEEVVEAITAYQEKTKLLF
                     VLAKVDNLVKNGRLSKLIGTVVGLLNIRMVGKASETGTLELLQKARGSKKSVQAAYDE
                     LVKAGYAGGRIVMAQRNNEKCCQQLSERIRETFPQADIKILPTSGLCSFYAEDGGLLM
                     GYEID"
     gene            12825..13997
                     /locus_tag="VQ540_001643"
     CDS             12825..13997
                     /locus_tag="VQ540_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HET2545416.1"
                     /translation="MKHFDTIVIGGGPAGMMATISSSFYGQKTLLIEKNRKLGKKLAG
                     TGGGRCNVTNNGSLDNLLAGIPGNGRFLYSVFSQFDNHDIINFFTENGVKLKVEDHGR
                     VFPASDKSRTIIEALEKKITELGGQVATQIEIVSVKKVDDQFVLKSADQTFTCEKLIV
                     TTGGKSYPSTGSTGFGHEIARHFKHTITDLEAAESPLLTDFPHKALQGISLDDVTLSY
                     GKHVITHDLLFTHFGLSGPAALRMSSFVKGGEVLSLDVLPQLSEKDLVTFLEENREKS
                     LKNALKTLLPERLAEFFVQGYPEKVKQLTEKEREQLVQSIKELKIPVTGKMSLAKSFV
                     TKGGVSLKEINPKTLESKLVPGLHFAGEVMDINAHTGGFNITSALCTGWVAGSNPI"
     gene            14012..14257
                     /locus_tag="VQ540_001644"
     CDS             14012..14257
                     /locus_tag="VQ540_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000438207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1697 domain-containing protein"
                     /protein_id="HET2545417.1"
                     /translation="MEQSPKKKKGTTLEHIILLRGVTPNGKNAIPKMSYLVDILTEAD
                     FQQVRTYIQSGNIILESNLALEEIREQVHTLLDFLQN"
BASE COUNT         4252 a         3105 c         2614 g         4323 t
ORIGIN      
        1 aatttctagt gcgccaaatt tcaagttcaa attagccatc aagaagtctt ctctggggga
       61 cttctttgga agctcttttc ttctacgcat ctcttttcaa aaactcttgt agcaaaaaag
      121 gagattttac aatctcctca taaaagcagc tattttacct aaatcttcaa gaatcggcgc
      181 atggatattc ctgatcccaa tgaaccaatg aaaaccccaa tcacaaatag tagggcaatc
      241 atcaacggac taaataaatc tggactaatc atggatagat tttgccctac caacgatttg
      301 ttgacagatt ggtaaacaat ttgataaaca ataaagacca aaacagatgg tgcgatagct
      361 cccaataaac cgataaaggc tccttctaac aagaacggtc cacggatata actgttttta
      421 gctccaacca agcgcatgat ttgaatttcg cgactgcggg aaataatggt aatacgaatg
      481 gtatttgaaa tcaagaaaac tgcgataaaa attaacaaag cagcaatccc tagtccccaa
      541 acacggataa atgaagctaa cttgaagagt ctttctgtat tggcaccgcc atcttgaacc
      601 tcagagacac cttcaatttt tttagcatct tcggctatag tttttacatc atttggagtg
      661 tttgcctcta caatataggc atcatagaga ggattggcat ctccttcaaa gattttccag
      721 ttatctccca ttatctcggt taatttttca tattgttctt ctttacttga aaaggtaaca
      781 cttttaaccg tagacatgtt cttcaaagaa tcatatacct tgtggtagtc attatttgta
      841 acagtttgac cttctttttc aattgtctga ctattatctt ccacatcctt tcggatataa
      901 actactacac ggacattatt ttcaatatct gtagctagtt tcgctgtatt gaaaataaca
      961 gatgcaaata ttgccaccaa ggtcaaagta atcatgactg aactgacagc agctactgtc
     1021 atccaaccat ttcgtttcaa actttttaag gcttcaaata aatggcgaaa aaatctacta
     1081 atcatcgtat ccatactctc cttttgattc gtcacgaacg acacggccat tttcaatggc
     1141 aatgacacgg tggcgcaagg tatttacaat ctggctatta tgagtcgcca tcaaaatagt
     1201 tgtcccttgt aggttaatcc gttccaagag attcataatt tcccatgaat tatccggatc
     1261 cagatttcct gttggctcat cagctatcaa tactttggga ttatttacaa ttgcacgcgc
     1321 aatcgcaatt cgctgctgct ccccacctga gagttcattt gggaaagaac gaaccttatg
     1381 cttcaatcca accaagtcca aaacttccat cactcgtctt ttgatattac ggcgattttc
     1441 cccgattact tccatagcgt aagcaatatt ttcatagaca gttttctttg gtaacaattt
     1501 ataatcttgg aagacaaccc caacactacg acgtagaagc gggacatctt tctttttgat
     1561 cttaaccaga ttaaaaccag caactgatag acttccttta tcgattttta cttcacgata
     1621 cagagaacga ataaaagttg acttccctgc tcctgaaggt cctacgatgt aagcaaattc
     1681 ccccggttga acgctgaccg aaacaccgcg tagagcagtc gttccgttgt cgtatttttt
     1741 aacgacatct ctcatttcaa taattgacat gtgagttcct ttctatctta gctaattcgc
     1801 cacttgagat aagcatctat aaaaccatct aggtccccat ccataacctt atctacctga
     1861 gcaacctcaa agctagttcg gtgatctttt accatagtat aaggcgtgaa gacataagaa
     1921 cggatttggc ttccccaagt gatctccttt ttctcacctt tgagagaatc tacctccgca
     1981 gccttcttat cttgctccat ttgatagagc ttagcctgca acatcttcat ggcacgatct
     2041 ctatttccat actgggtacg atccactgtt gattggacaa caattccagt tggaatgtgg
     2101 gttaaacgta cacctgttga aaccttattg acgttttgtc caccggcacc acctgaacgg
     2161 aaggtatcca tcttgatatc atcttcacgg atttccactt caatagtatc atccaattct
     2221 ggcatcactt ctacagatgt gaaagaggta tggcgacgtt tggcagagtc aaatggtgag
     2281 attcgcacta agcggtgaac acccatttct gacttgagga gaccataggc attaggccct
     2341 tcaaatgata aagttaccga cttaatacca gcctcatcac ctgcttggta atccaacact
     2401 tccactttaa agcctttagc attaccataa cgagtataca tacgaagcaa catatcaccc
     2461 cagtcctgcg cctcagtacc accagaacct ggatggattt ccaagatggc attgttgtgg
     2521 tcataaggtt ctgacaagag tagagtcatc tcgtagctgg tcattatctt atcaagttcg
     2581 gctaactgcg ctaccagttc atcatgcact gactcgtctt cagccaaaaa atccaataaa
     2641 atttcgactt catcctgcaa ctcttccatc ttatggaagg tattgtaagt gttttttaat
     2701 tcattcaatt cttgcgacgt tttttgggcc gcaatattat cgttccaaaa atcaggttct
     2761 gtcatcttgt tttccaagat ggcaatctct tcctctagcc cttcgaggtc aaagagaccc
     2821 cctgaaagaa gctaattttt cacgatttgc gtcaattttc tgacgaatta ctgaaatgtc
     2881 cataaatact ccttttttac attatttcat tatagcatat tttatcattt ctttccatct
     2941 tttgctctaa tccccttttc atgaaaaaag aagcctttgg acttcccttc ttacaagact
     3001 tttgctgaag tgcgagcgat ttcttccact tgaataccat ttgcttcaaa tttttctctc
     3061 aaggctggta aatcaattga ttcatcgatt tgcacttcga taatcacctt accatcctta
     3121 cgcggaatat tgactgtatg ggagatattc aaattttctt ctacaatcaa agaaacaatt
     3181 tttccaagaa caccaacttc atcttctgta acaaagcgta cacgaatccc ttcttcgcca
     3241 taacctgcaa tttcaagaaa ggcttggaaa acgtcacggt cagtaataac tccgtatact
     3301 tgatggttat ctacgacagg gagaatacca atcttatttt tcaacatcag ataagttgca
     3361 tcttctagac tagcatagcc tgagacagtg acaacatcgc gaatcatgac atcttttact
     3421 tttgtcttat tcagaagata attcatctca tagatagaaa gacttgttgc tttagatgga
     3481 cttgcttgtg caatggttcc ctcagtcacc aaaccaacca attgatcatt ttcgataaca
     3541 ggcagacggt gcaaaccttg ctctctcatc aaatctgctg catgagatac tgttgtatct
     3601 ggactaatat aaactacctt gcgggtcata aaatctttaa ctgccatgag acttctcctt
     3661 ttctattctt atccctatta tacaatcttt ttgcaaatct atcaaacgct tacatttctt
     3721 tttcaaaatt tagaaaagta tgaataagct agcaaaaaga gctctaaaat cgagctctgt
     3781 gaatgaaggt aagaaacttt tcattcgatt ttttcaatta ttagaaatta agctttcaat
     3841 gtagatgcag atttgtttgc aatctcaatc taccggctaa aacaatcctc tggatttgat
     3901 gattgcttcg caatcttcat ccaccgacta aaaagggccc ccggactata ttgatgatta
     3961 cttcgtaatc tttatctgcc ggctaaaaca atcctctgga tttgatgatt gcttcgcaat
     4021 ctcaatctac cgactaaaaa gggcccccgg actatattga tgattacttc gtaatcttca
     4081 tctgccgact aaaacaatcc actggattgt tttagccacc tagatatgct tttctgactt
     4141 cttctgatga agcgagttct tttcctgttc ctgataggac gatttttcct gtttccaata
     4201 catatcctcg gtcagagatt gcaagtgctt tattggcatt ttgttcaatc aagaggacgg
     4261 ttgttccttg cttctgaata tcttgaatga tatcaaaaat ctcttggatg aagattgggg
     4321 caagtcccat tgatggttca tctaaaagaa gaagttttgg tgttgacata agagcgcgtc
     4381 ccatggcaag catttgttgt tcccctcctg aaagagtagc tgcatcttgg ttcttacgtt
     4441 cttcaagacg aggaaagcgt gagaaaacct tcttcaagtt agcttgattt tcttcacgat
     4501 ttttctttaa gaaagctccc atttcaagat tttccataac agtcaagcca ggaaagacgt
     4561 ggcgtccttc tggaacttgt gaaagaccac ctgccacgat tttctgagct ggtatttttt
     4621 ggatttcttg acctaaaaat tcaatctttc ctgaacttgg tcgaaccaaa cctgacaagg
     4681 tgcgaagaat agttgtctta cctgcaccgt tggcaccgat aagggaaaca acttctcctt
     4741 cattaacttc aaagcttaca tcacggactg cttggatcat accgtaatgc acagaaagat
     4801 tttcaacttt taacatagac attaggcttc acctcctaga taagcttcga taacgcgttt
     4861 attggtctta atttcgtctg gagttccttg agcaattaaa cggccatatt caagtacgta
     4921 gatacgttct gttacttcca tgaccagatt catatcgtgt tcaatcaaca tgattgtaat
     4981 cttaaattca tctttgatac gacgaattaa ctcagtcaat tcggctgttt cctgtgggtt
     5041 catacctgct gctggttcat ctaagaagag aattttaggt tccgtagcaa gggcacgaac
     5101 aatttccaaa cgacgttgtt gtccgtagga aagattttta gcaagagtct ctgcatcacc
     5161 atctaaatca aagattttca acaattccaa agctttagcc tttaattctt tttcactctt
     5221 gtaaaaagct ggtaagcgta agaaactagt aaaaacatgc tgtttgtgat ggtttccaaa
     5281 agcaatcaaa acattatcta aaactgttaa atctttaaag agacggatat tttggaaagt
     5341 acgtccaagt cccaaagagg caatcttata aggtgatttc ccattcaaaa ggtgaccatc
     5401 tagggttact gttccctcgc ttggttcata aacaccggtc aaaaggttga aaagggtggt
     5461 tttcccagct ccgtttggac cgattaatcc aaccagttcc ccttcgttca attcaagagt
     5521 cacatctcca acagctgtta gaccaccaaa atgtttggtt aactgtttta cttcaagtaa
     5581 tgccattagt tttgttcctc cttcttagat tttttaaaga aacgtgatag gctcagttcc
     5641 cacgttccaa ggagtccacc tggtctgaaa atcattacca ataccaaggc taaagcgtaa
     5701 ataatcatac gcacactagc aacatcttgg agaagcatat tcaaaattcc cagaacaata
     5761 gccgaaacaa tcgcacctgt aatggaaccg agtccaccaa atacaacaat aatcaaaacg
     5821 ttgattgagt taatgaaggt gtaatctttc ggtacaacag acccgataaa tcctgcctga
     5881 agtgacccag caatacttgc agtaatggca ccaaagacaa aagcgatgat tttaatttta
     5941 gtcgtattaa ccccaactga ctcagcagcg atttcatctt cacgaacaga gagggttgaa
     6001 cggccaattg ggctacgcaa gaagttcaag gttgcaatgg ttgtaatcac gacaaagaag
     6061 taaaccattt gccaagttgt aaagttagga atccctaaga tacctgccgc accatttgta
     6121 agacttccac cattgatgat aaagatacgg ataatttcag aaacacctag agttgctacc
     6181 gcaagatagt cccccttcaa gcgcaaggtt ggaatgccga caagtaaggc aactgctcct
     6241 gaaagcaaag cccctacaag catagctcca aagaaggcac cgtaggttgg taatttagaa
     6301 ccaataatag ctgctgcata ggcaccaatc gccatgaaac cagcatgacc aagtgaaaat
     6361 tgtcctgaaa aaccaacgat taagttgaga ccaacagcca aaataatatt aattccaatt
     6421 tgttgtaaaa tctgtacata gaatagatta agtactccga ctgaaaccag tacactaatc
     6481 aagctatagc cagctaacaa aaggagtaac catagaatat taacttttaa attttccttc
     6541 atcgtttaca ccttctcttt cacattctta ccaaggatac cagctgggcg gacaatcaag
     6601 atcaacaaca agattccata aacaatggca tcacggaaat ctgacatccc aaaggcagtc
     6661 gcaaaggttt ccaatagacc aatcacaaag ccaccaagag ccgcaccagg aataattccg
     6721 ataccaccaa gtactgcggc aacgaaagat ttaagacctg gagtaacccc catcaaaggc
     6781 tcaagagagt tataataaag agcaatcaga acaccagccg cacccgcaag agcagaaccc
     6841 aaagcgaagg taaagctaat cgtacggttt acattgatcc ccatcaattg cgccgcgtcg
     6901 ctatctactg atactgcacg catggctttc cccatcttag tcttttggac aatgacttgt
     6961 aacaaaatca tcaaaatcaa ggaaatggcc aaaatcatta actgcacatt tgttaagcta
     7021 attggtccca aatcatatcg aactgtttga atcgcttgag ggaaggcacg ggtattggca
     7081 ccaaccagat agaccattcc atactccaat aggaaagaaa ccccaatagc cgtaatcaaa
     7141 acagcaatac gagtagagtg gcgcaaaggt cggtaagcaa gaaactcaat cacgacacca
     7201 agaatagctg tcgctagcat agctacaata agcgctacaa agaaattcat ttggaaagaa
     7261 ttgatcaaga aataaccgat aaaggctccc atcatataaa tatcaccatg ggcgaagttg
     7321 atgagcttga taattccgta aaccatggta tatcctaggg ctaacagcgc gtaaacacta
     7381 cctagaatca aaccatttac gagttgttgg agcataagat tcactctttc tatttataat
     7441 tccgagggtt ttccctcact ttttgatagg ttcttatact caatgaaaat caaagagcaa
     7501 actaggaaac tagccgcagg ttgctcaaag cactgctttg aggttgtaga taagactgac
     7561 gaagtcagtc acatatataa tccaaggcga cgttgacgca gtttgaagag attttcgaag
     7621 agtattaaat atcgaaacag ggagtgagtc aaaggctcat tccctatttc aacatttttc
     7681 tattatggtt ttacaacttc tgctgcttca actttaccat tgttcatggt catcatgtaa
     7741 gcagttttga ctgtgttgtg gtctgcatcg aagcttgttt gaccagttac accttcaaaa
     7801 tcttttgttt tagcaaggtt atccttgatt tcacctgaat ttttagcacc ttttgctgcg
     7861 tttgctacaa ggtgaactga atcataagcc aaggctgcaa atgttgaagg ctcttcattg
     7921 tacttagcac ggtaagcgtc aaggaaggct ttagctttag ctgaaacttc tacagtagtt
     7981 gagaagcctg agataaagta gatgtttgat gctttttcag cagttgcttg ttgtacaaac
     8041 tcctcaccgt tgaatccatc accaccaacg attggtttgt caattcccat gccacgcgct
     8101 tggtttacaa tcttaccagc ctcattatag taaccaggaa caacgatagc atcaaagtct
     8161 ttccctttca tgtttgtaag ggctgcttgg aagtctgtgt cacctgctac gaaagtttca
     8221 tctgcaacga tttcaccctt gtatgactcg cggaaagatt tagcaatccc tttagcatag
     8281 tcactggcat tgtcagtgta aagaacaact ttcttagcat ttaatttttc agaaacatag
     8341 tttgagataa tttttccttg gaagctatct tggaaagttc caataaagag gtaatcttga
     8401 cctttagtca atccatcttg agtcgcactt ggtgagatca atggaacacc tgcttttgta
     8461 gcgttcgcta ccgcagctgc agtcgcacca gatgtcgcag gtcctacgac tgctgatact
     8521 ttagattggg ttacaaggtt agttgtaact gaagcagcct cagctgtttc agacttatta
     8581 tctttatcga ctacttcgat ttgttttcca tcgataccac ctgcggcatt gatttcatca
     8641 acagccaatt gggcaccttt ttgttcagct gttccgtatg cagctaaaga acctgattct
     8701 tcaaagttaa acccgatttt aattgtcttt tcctctactg agttaccagc agtgttgact
     8761 gctccagact tcacttctac acaggctgca agaagtgcta cacttgcaag cgccacaaac
     8821 gatagggcaa attttttctt catctttttg tctccttatt tcttaaatag tctgttaaga
     8881 atataccgaa ttatcagaaa attgtcaatg ttttccttga actttttcga tgataacgtt
     8941 ttcctatcga taaagattgc ccacaaaggg tgtttccaac tcttggatat gacaaaccct
     9001 aactttttta ataaattttt ccttgctcaa gcgtccgacc aattgctcca cttcttgagt
     9061 tggaacatag agttgtaagt aacgatgttt cttggaatga taggtaatat ctccataatc
     9121 ctgcagtttt ttggcatcac gattatagta aagatagata atcaagccag agcgattgac
     9181 tttttcaaac atgataaatc ctctttctaa gaaatctctc cctattatac caaaaaaagc
     9241 aaacccagtc gagtttgcct tctatcatca ttagttcaat gaattgttgg ccataatttc
     9301 atcaataaag ccatattcaa gtgtttcctg ggcgctcatc cagttatcac gttctgcatc
     9361 tgcatggact ttttccattg actgacctga attttcagcc aagatttttt ccaaggtatt
     9421 acgagttttg agcaagtgtt ctgcagcgat agccatatca gtttgttggg taccaccacc
     9481 tgtaccgccc attggttggt gaatcatgta ttcagcattt ggaagcatga aacgtttgcc
     9541 ttttgctcca cttgatgcga tgactgttcc catagatgca gccattccca taacaatggt
     9601 ttggacatct gccttgataa agttcatggt atctacgatt gccaaaccag ctgaaacaga
     9661 accacctggt gtattgacat aaaggtaaat atcttttgta ctatcttggg catccaagaa
     9721 aagcagttgg gcaataacag agttagccat attgtcttca accggacctg tcagcataat
     9781 gatgcggtct ttgagaagac gtgagtaaat atcgtaagaa cgttctccac ggcttgtttg
     9841 ttcaataact acaggaatca ttcatttctc cttttgagtt ttaattttgt tggtcaaatg
     9901 actgaagata agactattat aatatcttgg tcaaaaaagg tcaaattttt gctctgcttt
     9961 cattagacag aaacaaaaac ccaacctcct ttcgtgactg gaaatacttt tccaagtcat
    10021 tcttcttttc gatcttattt tgtaccgaac aagcggtctc cagcatctcc aagacctgga
    10081 acgatataac cgtgttcgtt caaacgttca tccaaggctg ctgtaaagat ttctacatct
    10141 ggatgagctt cttgaagggc ttttacaccc tctggagcag atacaaggca gacaaatttg
    10201 atatttgatg cgccacgttt tttaagagaa tcaacagcca agattgctga gccacctgtt
    10261 gccaacattg ggtctactac aaaaatttga cgttggtcaa tgtcctcagg caatttcacc
    10321 aagtattcaa ctggttgaaa tgtttcttca tcacggtaca taccgatgtg gccaacttta
    10381 gcagctggaa ccaagctcaa gagaccatca accatcccga tacctgcacg caagattggg
    10441 acgatggcca atttcttacc tgccaattgt ttttgaactg tttttgtaat tggtgtttcg
    10501 atttccacat cttctagtgg aagatcacga agtacttcat accccatcaa cattgcaatc
    10561 tcatctacta gctcacgaaa agcttttgta gaagtatctg tacgacgcaa gattgacaat
    10621 ttgtgttgaa tcagtgggtg attaataact tcaatttttc ccatttttgg aattccttct
    10681 ttcaatttat tcttcttatt ataccaaaaa acgggttaaa aatctttcta aaccatttat
    10741 ttttgataat ttttacatta gatcagcctc tttaagagct gtctgtactg tctcaagtgg
    10801 taaatgggtc aattctgtcc ctttttcttg ataaaggtat tgggcgtagt cgtccattcg
    10861 gtactggttg atataaacca cacgcttgca gccgacctga agcaattgtt ttgtacagtt
    10921 gagacaagga aaatgggtta cataggctgt aaagcctttg ggaacaccac gctcagcacc
    10981 ttgaaggata gcattgacct cagcgtgaag ggtgcgaaca cagtggcctt caatgaccaa
    11041 acattcgtga tcaatacaat gctcagtccc tgacaccgaa ccattgtaac cagtggaaat
    11101 aaccttatta tcttttacca gaatcgcgcc cactttagca cgtttacaag tggaacgatt
    11161 cgcaattagt agagcttggg ctgcaaaata ctcatcccag gccagtcttt tttcagtcat
    11221 ctcttttctc ctttttctct attttttaaa aaatggtaaa cctaaatctg caatcttttc
    11281 agctggtacc ttcatgccat ccttgatcca ttttagaagg acagagacga tggctgagct
    11341 ccagaaggaa tgaagataag agctgacacc ttttgatttc ccatggtatt tttctagaaa
    11401 ttcctgcatg gcttggacaa agattttttc cagatggtaa tccaaggcca attgaattac
    11461 tctagcttcc tttctggcct cccggaaaag gtgaacccaa accaaataaa ggtctgtctt
    11521 taaatcgtaa tgatgcagct gttccataat attgtggaca gttcgtttaa agacgctctc
    11581 taaaatttcc tctttggagt cataattgcg ataaaaggcc gcacgcgaaa cacctgcacg
    11641 tttgaccaat tcagaaatac taatcttggt cagttccttt ttttccaaga gttgcaagag
    11701 ggctgtttca atggcttctc tggttaataa attggattct tggtttgatt ttctgagatt
    11761 ttcaagagac ttttcagaga ttctacgttc agacataaca ttttctttct acttgtcaca
    11821 acagacggat gatgcttttg tttcaagggt tttcatgata taattgtaaa aaaagacaga
    11881 acctttgtca atgtataact gacaaagatg gagaatttct atgacttgga agattattgc
    11941 tgactctggt tgtgattatc gtcaactgcc aacaccagct attaacacaa cctttgtaag
    12001 tgtcccctta accattcaag tagctgatca ggtctttgtt gatgacgcca gtctcgatat
    12061 tgaccaaatg atggaaacca tgtatgcaac tgcagaagct tcaaaatcgg cttgtccaag
    12121 cccagatgac tatttgcgag catttgaagg tgccaaaaac attttcctag taaccatcac
    12181 aggtaccctt tctggcagtc acaatagtgc tcaactagca aagaatattt atctggaaga
    12241 ccatcctgac actaagattc atgtgattga tagtttatct gctggtggtg aagttgacct
    12301 actcgtagaa aaattgaatg acttgattga ccagggcttg tcttttgaag aagtggttga
    12361 agctatcacc gcctatcaag aaaaaactaa gttgctcttt gtcctagcca aagtcgataa
    12421 cttggtgaag aacggccgtt tgagcaagct tatcggtacg gtcgttggcc ttctcaacat
    12481 tcgtatggtc ggaaaagcta gtgaaactgg aactctcgaa ttgctacaaa aagcaagggg
    12541 atcaaagaaa tcagttcaag ctgcctatga tgagttagta aaagctggat atgctggtgg
    12601 ccgtattgtc atggcccaac gcaataacga aaaatgttgt caacagctct cagagcgaat
    12661 ccgtgaaacc ttcccacaag cggatattaa aattctacca acctctggtc tctgcagttt
    12721 ctatgcagaa gatggcggtt tgctgatggg ctatgaaatt gattaattgt attcttgaca
    12781 agaggtgacc atcatctctt gtttttttgt ggtacaatag agctatgaaa cattttgata
    12841 ctattgtcat cggtggggga cctgctggta tgatggctac gatttccagt agcttttatg
    12901 gacagaaaac cctcctcatc gaaaaaaatc ggaaacttgg aaaaaaatta gctgggactg
    12961 gtgggggacg ttgcaatgtg accaacaatg gtagcttaga caacctgcta gctggaattc
    13021 ctggaaacgg acgctttctt tacagtgttt tctcccagtt cgataatcat gacatcatca
    13081 acttttttac agaaaatggt gttaaactta aggtcgaaga ccacggacgc gtctttccag
    13141 ccagtgacaa gtctcggact attatcgaag ctttggaaaa gaaaatcacc gaactaggtg
    13201 gtcaagttgc tactcaaata gaaatcgttt ctgttaaaaa agtagatgac cagtttgtcc
    13261 ttaagtcagc ggatcaaacc ttcacttgtg agaaactcat tgtcacaaca ggtggtaagt
    13321 cttatccttc gactggttcg actggttttg gtcacgagat tgctcgccat tttaagcata
    13381 ccatcaccga tcttgaggct gctgaaagtc ctttattaac agattttcca cataaagcct
    13441 tacaagggat ttctttggac gatgtgaccc taagttatgg taagcatgtc atcactcatg
    13501 atttactctt tacccacttt ggtttgtcag gtcctgctgc cctacgcatg tctagctttg
    13561 tcaaaggtgg ggaggttctc tcactcgatg ttttgcctca actttctgag aaggacttgg
    13621 ttacatttct agaagaaaat cgggaaaaat ccttgaaaaa cgctttaaaa accttgttac
    13681 cagaacgctt ggccgaattt tttgtacaag gatatcctga aaaagtcaaa caactgactg
    13741 aaaaggaacg agaacaactt gtccagtcca ttaaagaact taaaattcct gtaactggaa
    13801 aaatgtccct tgcaaagtcc tttgttacca agggtggagt cagtctcaag gaaatcaatc
    13861 ctaaaaccct tgaaagtaag ctggtacctg gcctccactt tgcaggcgaa gttatggata
    13921 tcaatgccca cacaggtggc tttaacatca cttctgccct ctgtaccggc tgggtggcgg
    13981 gatcaaatcc aatctaaata tacattacta aatggaacaa tcccccaaaa aaaagaaagg
    14041 aactactttg gaacatatta tcttgctaag gggagtcact cctaatggaa aaaatgctat
    14101 ccctaaaatg tcttatctag tagatatctt gacagaagct gattttcaac aagttcgaac
    14161 ttatattcaa agtggaaata ttattcttga aagtaactta gctctcgaag aaatacgaga
    14221 acaggttcat actctattag acttcctgca aaactagaat cctagttcat gattgataat
    14281 accagcactc aaat
//
LOCUS       DAVBDR010000052        14254 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.052, whole genome shotgun sequence.
ACCESSION   DAVBDR010000052 DAVBDR010000000
VERSION     DAVBDR010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14254)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14254)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14254
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.052"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            3..350
                     /locus_tag="VQ540_001645"
     CDS             3..350
                     /locus_tag="VQ540_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2545418.1"
                     /translation="MLRLPYKKQKISHFTVSEDKDICRYIRQQLYYQNLFWMKEQAEA
                     YQKGENILTYGLKEWYPQIRPIVGKFFQIEQDLTSYYQHFYTYYQKNPQNDWQKLYPP
                     AFYQQYFLKNMVE"
     gene            369..2171
                     /gene="pepF"
                     /locus_tag="VQ540_001646"
     CDS             369..2171
                     /gene="pepF"
                     /locus_tag="VQ540_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HET2545419.1"
                     /translation="MVLQRNEINEKDTWDLSTIYPTDQAWEEVLKDLTEQLETVAQYE
                     GHLLDSADNLLEITEFSLEMERQMEKLYVYAHMKNDQDTREAKYQEYYAKAMTFYSQL
                     DQAFSFYEPEFMEISEKQYADFLEAQPKLQVYQHYFDKLLQGKDHVLSQREEELLAGA
                     GEIFGSASETFAILDNADIVFPYVLDDDGKEVQLSHGIYTRLMESKKREVRRGAYQAL
                     YATYEQFQHTYAKTLQTNVKVQNYRAKVRNYKSARHAALAANFVPESVYDNLVAAVRK
                     HLPLLHRYLELRSKILGISDLKMYDVYTPLSSVEYSFTYQEALKKAEDALAVLGEDYL
                     SRVKRAFSERWIDVYENQGKRSGAYSGGSYDTNAFMLLNWQDNLDNLFTLVHETGHSM
                     HSSYTRETQPYVYGDYSIFLAEIASTTNENILTEKLLEEVEDDATRFAILNNFLDGFR
                     GTVFRQTQFAEFEHAIHQADQNGEVLTSDFLNKLYADLNQEYYGLSKEDNPEIQYEWA
                     RIPHFYYNYYVYQYSTGFAAASALAEKIVHGSQEDRDRYIDYLKAGKSDYPLNVMRKA
                     GVDMEKEDYLNDAFAVFERRLNEFEALVEKLGLA"
     gene            2173..2886
                     /locus_tag="VQ540_001647"
     CDS             2173..2886
                     /locus_tag="VQ540_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HET2545420.1"
                     /translation="MVESYSKNANHNMRRPVVKEEIVDLMRQRQKQVTGFLKELENFA
                     RKENIPIIPHETVAYFRFLMETMQPKNILEIGTAIGFSALLMAEHAPNAKITTIDRNP
                     EMIGFAKENFAQFDSRKQITLLEGDAVDVLSTLTESYDFVFMDSAKSKYIVFLPEILK
                     HLEVGGVVVLDDIFQGGDVAKDIMEVRRGQRTIYRGLQKLFDATLDNPELTATLVPLG
                     DGILMLRKNVADVQLSESE"
     gene            2953..3894
                     /gene="prsA"
                     /locus_tag="VQ540_001648"
     CDS             2953..3894
                     /gene="prsA"
                     /locus_tag="VQ540_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase PrsA"
                     /protein_id="HET2545421.1"
                     /translation="MKKKLLAGAITLLSVATLAACSKGSEGADLISMKGDVITEHQFY
                     EQVKNNPSAQQVLLNMTIQKVFEKQYGSELDDKEVDDTIAEEKKQYGENYQRVLSQAG
                     MTLETRKAQIRTSKLVELAVKKVAEAELTDEAYKKAFDEYTPDVTAQIIRLNNEDKAK
                     EVLEKAKAEGADFAQLAKDNSTDEKTKENGGEITFDSASTEVPEQVKKAAFALDVDGV
                     SDVITATGTQAYSSQYYIVKLTKKTEKSSNIDDYKEKLKTVILTQKQNDSTFVQSIIG
                     KELQAANIKVKDQAFQNIFTQYIGGGDSSSSSSTSNE"
     gene            complement(4011..4352)
                     /locus_tag="VQ540_001649"
                     /pseudo
     CDS             complement(4011..4352)
                     /locus_tag="VQ540_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            4765..4860
                     /locus_tag="VQ540_001650"
                     /pseudo
     CDS             4765..4860
                     /locus_tag="VQ540_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(5113..5733)
                     /locus_tag="VQ540_001651"
     CDS             complement(5113..5733)
                     /locus_tag="VQ540_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HET2545422.1"
                     /translation="MKLYFVRHGRTLWNQEGRFQGASGDSPLLPESIETLKRLGQYLK
                     EIPFDQIYSSDLPRAVKSAEIIQSQLYTPCSLEIVPNLREWQLGKLEGLKIATLEAIY
                     PQQIQAFRSNLAQFDTRMFGAESLYSTTQRTIQFIKSLKDSPAERILIVGHGANLTAS
                     LRTLLGYKEPLLRKDGGLANASLTIIETHDFETFTLNTWNDTSYQS"
     gene            complement(5733..6215)
                     /locus_tag="VQ540_001652"
     CDS             complement(5733..6215)
                     /locus_tag="VQ540_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HET2545423.1"
                     /translation="MAKKVKIKKTLVEQILSKAAIPHQGIQINALEGELPQGYERDQI
                     FKTLALLGDKTGPIIGIVPITQHLSEKKLAKISGNKKVSMIPQKDLEKTTGYIHGANN
                     PVGIRQKHNYPIFIDKIALDLDRMIVSAGEVGHSIIVAPQDLASFVKADFVDILEDIK
                     "
     gene            complement(6215..7057)
                     /locus_tag="VQ540_001653"
     CDS             complement(6215..7057)
                     /locus_tag="VQ540_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HET2545424.1"
                     /translation="MLSWLARVIKGIVIALGFILPGISGGVLAAILGIYERMIGFLAH
                     PFKDLKENVLYFIPVAIGMLLGIGLFSYPIEYLLENYQVFVLWSFAGAIIGTVPSLLK
                     ESTRESDRDKIDLAWLWTTFIISGLGLYALNFVVGTLSASFLNFVLAGALLALGVLVP
                     GLSPSNLLLILGLYAPMLTGFKTFDLLGTFFPIGIGAGATLIVFSKLMDYALNNYHSR
                     VYHFIIGIVLSSTLLILIPNAGNAESIQYTGLSLVGYVIIAFFFALGIWLGIWMSQLE
                     DKYK"
     gene            complement(7152..7952)
                     /locus_tag="VQ540_001654"
     CDS             complement(7152..7952)
                     /locus_tag="VQ540_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 25 protein"
                     /protein_id="HET2545425.1"
                     /translation="MRKQIHPLILFSFFGIMMFILIINRPLNDSQSFKTKSNIAQIEA
                     QALKHLDKPIIDLSGWQRPEEINYDALSQNISGAIVRVHSGAQTTKENDASFINGIDK
                     AYKSHITELQKRNVPVAVYAYVAGKSVQEMEKAAEVFYNAASPYSPSYYWLDVEDKTM
                     SNMNEGVENFRAKLASLGAKNIGIYVGVYFMEEHSIDTGKFTSVWIPSYGSDSGFLES
                     SPKTDLDYDIHQYTSKGKIAGFDHDLDINVISPLKNKEETFRKLFLKP"
     gene            8096..9475
                     /gene="glmU"
                     /locus_tag="VQ540_001655"
     CDS             8096..9475
                     /gene="glmU"
                     /locus_tag="VQ540_001655"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HET2545426.1"
                     /translation="MSNFAIILAAGKGTRMKSDLPKVLHKVAGISMLEHVFRSVGAIQ
                     PEKTVTVVGHKAELVEEVLAGQTEFVTQSEQLGTGHAVMMTEPILEGLSGHTLVIAGD
                     TPLITGESLKNLIDFHINHKNVATILTAETDNPFGYGRIVRNDNAEVLRIVEQKDATD
                     FEKQIKEINTGTYVFDNERLFEALKNINTNNAQGEYYITDVIGIFRETGEKVGAYTLK
                     DFDESLGVNDRVALATAESVMRRRINHKHMVNGVSFVNPEATYIDIDVEIAPEVQIEA
                     NVTLKGQTKIGAETVLTNGTYVVDSTIGAGAVITNSMIEESSVADGVTVGPYAHIRPN
                     SSLGAQVHIGNFVEVKGSSIGENTKAGHLTYIGNCEVGSNVNFGAGTITVNYDGKNKY
                     KTVIGDNVFVGSNSTIIAPVELGDNSLVGAGSTITKDVPADAIAIGRGRQINKDEYAT
                     RLPHHPKNQ"
     gene            9485..10030
                     /locus_tag="VQ540_001656"
     CDS             9485..10030
                     /locus_tag="VQ540_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HET2545427.1"
                     /translation="MEFEEKTLSRKEIYQGPIFKLVQDQVELPEGKGTARRDLIFHNG
                     AVCVLAVTDEQKLILVKQYRKAIEAVSYEIPAGKLEVGENTAPVAAALRELEEETAYT
                     GKLELLYDFYSAIGFCNEKLKLYLASDLTKVENPRPQDEDETLEVLEVSLEEAKELIQ
                     SGHICDAKTIMAVQYWELQKK"
     gene            10042..10356
                     /locus_tag="VQ540_001657"
     CDS             10042..10356
                     /locus_tag="VQ540_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="foldase"
                     /protein_id="HET2545428.1"
                     /translation="MGKSLLTDEMIERANRGEKISGPPLLDDNEETKILPTSSSRFGY
                     ANPKDHGFSQETLKIQVEPSIHKSRRIENTKRNVFNSKLNKILFAVIFLLILLVLAMK
                     LL"
     gene            10373..11065
                     /locus_tag="VQ540_001658"
     CDS             10373..11065
                     /locus_tag="VQ540_001658"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HET2545429.1"
                     /translation="MKIGIIAAMPEELAYLVQHLDNTQEQVVLGNTYHTGTIASHEVV
                     LVESGIGKVMSAMSVAILADHFQVDALINTGSAGAVAEGIAVGDVVIADKLAYHDVDV
                     TAFGYAYGQMAQQPLYFESDKTFVAQIQESLSQLDQNWHLGLIATGDSFVAGNDKIEA
                     IKSHFPEVLAVEMEGAAIAQAAHALNLPVLVIRAMSDNANHEANIFFDEFIIEAGRRS
                     AQVLLTFLKALD"
     gene            11142..11633
                     /gene="rocS"
                     /locus_tag="VQ540_001659"
     CDS             11142..11633
                     /gene="rocS"
                     /locus_tag="VQ540_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein RocS"
                     /protein_id="HET2545430.1"
                     /translation="MSIEMTVSEIAEVLGLSRQAINNRVKELPEEDTDKNDKGVTVVT
                     RSGLIKLEEIYKKTIFEDEPVSEDVKQRELMEILVDEKNAEILRLYEQLKAKDRQLSE
                     KDEQMRIKDRQIAEKDKQLDQQQQLTLQAMKDQENLKLELDQAKEEVQSTKKGFFARL
                     FGG"
     gene            11731..12321
                     /locus_tag="VQ540_001660"
     CDS             11731..12321
                     /locus_tag="VQ540_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HET2545431.1"
                     /translation="MERLEDYIAFDLEFNQHEGQTHLIQVSAVRFRDGREIDAYDSYV
                     HTSVPLKSFINGLTGITAETLKDAPPVEKVLEEFQEFVGSLLMIGYNAAKSDLPILAE
                     HGLDYSQQYKVDLYDEAFERRSSDLHGIANLKLQTVASFLGFQGQSHNSLEDARMTAR
                     VYESFLESDQARELLETESSLSNNPFGVLDLSQLFD"
     gene            12330..14093
                     /locus_tag="VQ540_001661"
     CDS             12330..14093
                     /locus_tag="VQ540_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HET2545432.1"
                     /translation="MKPEKPKKLGLKQIYLNLDKILFLFFLIFMIVEYLWVPFNSWLA
                     SFLLDQTGYLFISYNNVLAILTHSPLISLAFLALIVINLLVAYFQIGLLFIGARHLLY
                     NEKRRLIEYIRKVFHESFGFMKKLTCAKALFIFFYIAMLFPFIRKMLKIYYLNKIVIP
                     EFIQAYLEDKYWMWWLSILLLSLIFLYVSVRLMFALPKIVYDQLTVREAVMFSLEKTK
                     KRVTFYAWNLFYILLKAHLLFYLPLIPLLLAQTLVDDITQRESLILGILNFVVIKNLY
                     YMALTYFLVKFVSFLTGKELDMLPRREKDHIVRWGVMTCASLFFALEGYIYLEAPMVH
                     LPQLISHRGVSNANGIQNTVESLETTAQLKPDLVETDVQETKDGQFVMMHDANLKNLA
                     GINKSPQDLNLEELKGIDIFENGYQTKISSFEDYLSRANELGQKLLIEIKTSKKDSPD
                     MMNRFLARYAAKLKIYGHQIQSLDYHVVEKVRQYDAELPVYFIMPYNSVFPKTRATGY
                     TMEYSTLDEYFVSKLWTTDQKLYVWTVNDSEAISKSLHLGVDGVITDDLEKVQREIEV
                     AQEDPEYTDLLLKKALEFFEF"
BASE COUNT         4485 a         2552 c         2969 g         4248 t
ORIGIN      
        1 aaatattgcg tcttccctat aagaaacaaa aaatatctca ttttacagtt tctgaggaca
       61 aggacatctg tcgctatatc cggcaacaac tttattatca aaatctcttt tggatgaaag
      121 aacaagcaga agcctatcaa aagggagaaa atatcctgac ttatggactg aaagaatggt
      181 atccacaaat tcgaccaata gtgggcaaat ttttccagat tgaacaagac ttgactagct
      241 attatcagca cttttatacc tattaccaaa aaaatcctca aaatgattgg caaaagcttt
      301 atccaccagc cttttatcag caatatttct tgaaaaatat ggtagaatag aaaggatgga
      361 ggaatctaat ggtattacaa agaaatgaaa taaatgaaaa agatacatgg gatctatcaa
      421 cgatctaccc aactgaccag gcttgggaag aagtcttaaa agatttaaca gaacaattgg
      481 agacagtagc ccagtatgaa ggccatctct tggatagtgc ggataaccta ctagaaatca
      541 ctgaattttc tcttgaaatg gaacgccaga tggagaagct ttacgtttat gctcatatga
      601 agaatgacca ggatacacgt gaagctaagt atcaagagta ctatgccaag gccatgacat
      661 tctacagcca gttagaccaa gccttttcat tctatgagcc tgaatttatg gagattagcg
      721 aaaagcagta tgctgacttt ttagaagctc aaccaaagct gcaggtttat caacactatt
      781 ttgacaagct cttgcaaggc aaggatcacg ttctctcaca acgtgaagaa gaattattgg
      841 ctggagctgg agaaatcttt ggttcagcaa gtgaaacctt cgctatcttg gacaatgcgg
      901 atattgtgtt cccttatgtc ctagacgatg atggtaaaga agttcagcta tctcatggga
      961 tttacacacg tttgatggag tctaaaaaac gtgaggttcg ccgtggtgcc tatcaagctc
     1021 tttatgcgac ttacgaacaa ttccaacaca cctatgccaa aaccttgcaa accaatgtta
     1081 aggtgcaaaa ttaccgtgct aaagttcgta actacaagag tgctcgtcat gcagccctcg
     1141 cagcgaattt tgttccagaa agtgtttatg acaatttggt agcagcagtt cgcaagcatt
     1201 tgccactctt acatcgctat cttgagcttc gttcaaaaat cttggggatt tcagatctca
     1261 agatgtacga tgtctacaca ccgctttcat ctgttgaata cagttttacc taccaagaag
     1321 ccttgaaaaa agcagaagat gctttggcag tcttgggtga ggattacttg agccgtgtta
     1381 aacgtgcctt cagcgagcgt tggattgatg tttacgaaaa tcaaggcaag cgttcaggtg
     1441 cctactctgg tggttcttac gataccaatg cctttatgct tctcaactgg caggacaatc
     1501 tggacaatct ctttactctt gttcatgaaa caggtcacag tatgcattca agctatactc
     1561 gtgaaactca gccttatgtt tacggagatt actctatctt tttggctgag attgcctcaa
     1621 ctaccaatga aaatatcttg acggagaaat tattggaaga agtggaagac gacgcaacac
     1681 gctttgctat tctcaataac ttcctagatg gtttccgtgg aacagttttc cgccaaactc
     1741 aatttgctga gtttgaacac gccattcacc aagcagatca aaatggggag gtcttgacaa
     1801 gcgatttcct aaataaactc tacgcagact tgaaccaaga gtattatggt ttgagtaagg
     1861 aagacaatcc tgaaatccaa tacgagtggg ctcgcattcc acacttctac tataactact
     1921 atgtatatca atattcaact ggctttgcgg ccgcctcagc cttggctgaa aaaattgtcc
     1981 atggtagtca agaagaccgt gaccgctata tcgactacct caaggcaggt aagtcggact
     2041 atccacttaa tgtcatgaga aaagctggtg ttgatatgga gaaggaagac tacctcaacg
     2101 atgcctttgc agtctttgaa cgccgtttaa atgagtttga agcccttgtt gaaaaattag
     2161 gattggcata aaatggttga atcgtatagt aagaatgcta accataacat gcgtcgtcct
     2221 gtcgtcaaag aagaaattgt agacttgatg cgtcagcgtc aaaagcaggt cacaggtttc
     2281 ttgaaagaat tggaaaactt tgcccgcaag gaaaatattc ctattattcc ccatgaaacg
     2341 gttgcttatt tccgttttct tatggaaacc atgcagccta aaaatattct ggaaattggg
     2401 acggctatcg gtttttcagc tctcttgatg gctgaacatg cgccaaatgc taagattaca
     2461 actattgatc gtaatccaga aatgattggt tttgccaagg aaaattttgc ccagtttgac
     2521 agtcgcaagc aaatcactct cctagaggga gatgcggtgg atgtcttatc tacactgaca
     2581 gagtcttatg atttcgtctt tatggattct gccaagtcta aatacatcgt ctttctgcca
     2641 gaaatcctca aacatttgga agttggtggt gtggttgtct tggatgatat ttttcaaggt
     2701 ggtgatgttg ccaaggatat tatggaagtc cgtcgtggtc agcgaaccat ttatcgaggc
     2761 cttcaaaaat tatttgatgc aaccttagac aatccagaac tcaccgcaac attagtgcct
     2821 ttaggagatg gtattctcat gcttcgtaaa aatgtagcag atgttcaact gtctgaaagc
     2881 gaatgatttt cagaaaaatt taagaaaaaa tagtaaaata gatagagtaa cacttatctc
     2941 aaaggagtag acatgaagaa aaaattattg gcaggtgcca tcacactatt atcagtagca
     3001 actttagcag cttgttcgaa agggtcagaa ggggcagacc ttatcagcat gaaaggggat
     3061 gtcatcacag aacatcaatt ttatgagcaa gtgaaaaaca acccttcagc ccaacaagtc
     3121 ttgttaaata tgaccatcca aaaagttttt gaaaaacaat atggctcaga gcttgatgat
     3181 aaagaggttg atgatactat tgccgaagaa aaaaaacaat atggcgaaaa ctaccaacgt
     3241 gtcttgtcac aagcaggtat gactcttgaa acacgtaaag ctcaaattcg tacaagtaaa
     3301 ttagttgagt tggcagttaa gaaggtagca gaagctgaat tgacagatga agcctataag
     3361 aaagcctttg atgagtacac tccagatgta acggctcaaa tcatccgtct taataatgaa
     3421 gataaggcca aagaagttct cgaaaaagcc aaggcagaag gtgctgattt tgctcaatta
     3481 gccaaagata attcaactga tgaaaaaaca aaagaaaatg gtggagaaat tacctttgat
     3541 tctgcttcaa cagaagtacc tgagcaagtc aaaaaagccg ctttcgcttt agatgtggat
     3601 ggtgtttctg atgtgattac agcaactggc acacaagcct acagtagcca atattacatt
     3661 gtaaaactca ctaagaaaac agaaaaatca tctaatattg atgactacaa agaaaaatta
     3721 aaaactgtta tcttgactca aaaacaaaat gattcaacat ttgttcaaag cattatcgga
     3781 aaagaattgc aagcagccaa tatcaaggtt aaggaccaag ccttccaaaa tatctttacc
     3841 caatatatcg gtggtggaga ttcaagctca agcagtagta catcaaacga atagtccaaa
     3901 tcaatgagtc agggaaaaaa actcgacttc aggaaaaaat gaagcaaaca ttcccacaat
     3961 aaaacgcata gtacaaggtt tgtactgacc ccaaaagtta gacaattaat ttatctgaag
     4021 gatttagttc tgtattgcac agggctaagt ccttttagtt ttaccttaat tctcttattg
     4081 ttgtaataat caatatagtc tataatggct tgttccaatt gattaagtga tttaaatgtt
     4141 ttctcatagc cataaaacat ttcggatttt aaaatgccaa agaaagattc catcctaccg
     4201 ttgtcttggc tgtttccttt gcgtgacata gatgcttgaa ttcccttact ctctaggaag
     4261 cgatgataag aatcgtgttg gtattgccag ccttggtcac tatggagaat cgtattctcg
     4321 tagtgcttct ctttgaatgc ctgttccaac attaacgatc aatcaattta atcatgtacc
     4381 taatattaga attgtttatc ccaaatttat ttgaaagctt ctctaagcta tatccttgtt
     4441 ttctaagttc atagatctga actttatcat cataagttaa tttcataata aaaacacccc
     4501 aaaagttaga ttttttctgt ctaacttttg gggtgtagtt catgtacacc tgatatgatg
     4561 cgttttataa ttttaaagac tttttgacca gcctcatttt tttaacttga tactcagtga
     4621 aaagcaaaga ttaaactagg aagctagctg taggctgctc aaagaacagc tttgaggttg
     4681 cagataaaac ttgtgaggtc accaacatat ataatgtgaa gctgacgtga cttgaataga
     4741 ttttagaagg gtatgagtct ggaagtttta atggataatg caagattcca tagaatgggt
     4801 aagctagagt tcttatgtga agagtttggg cataaacttt taccttttcc tccctactca
     4861 tcttagtata gaaaagtgaa tctaaaatag tacataactg cttctaaaac attcttataa
     4921 attgatttaa attctcaaat catattattc agttcttatt tcattttgct ctacaatcct
     4981 gttgagaaga cacgtgttca tatcaaaaag gtattggcaa gttgcaatac ctttttacaa
     5041 ggttcttttg tcttattttt gtttcaactg actatatctc ctatggttct agttcagaag
     5101 gctaggctat aattatgatt gataagaagt atcattccaa gtattgagag tgaatgtttc
     5161 aaaatcatgg gtttctataa tggtcaggct ggcatttgct agaccgccat ctttacgaag
     5221 aagtggttct ttatagccta ggagagtacg aagactggca gtaagattgg cgccgtgtcc
     5281 gacaattaga atacgctcag ctggactatc ttttaatgat ttgataaatt ggatggtccg
     5341 ttgagttgta ctatagaggg attcggctcc gaacattcga gtgtcaaatt gagcaagatt
     5401 tgaacgaaaa gcctggattt gttgcgggta aatagcttcc aaggttgcaa ttttcaaacc
     5461 ttctaacttc ccaagttgcc attcacggag attaggaacg atttctaaag aacagggggt
     5521 atagagttga ctttggataa tctcagcaga tttgaccgct cgaggtaaat cacttgaata
     5581 aatctgatca aaaggaattt ccttgagata ctggccaagt cgttttaggg tttcaatgga
     5641 ttcaggaaga agaggagaat caccgctagc accttgaaaa cgaccttctt ggttccagag
     5701 ggtacgaccg tggcggacaa agtagagttt cattacttga tgtcctccaa aatatctaca
     5761 aagtctgcct ttacaaagct agccaagtct tgtggcgcga cgataatgct gtgtccgact
     5821 tcgcctgcag agacaatcat tcgatccaaa tctagagcaa ttttatcgat aaaaatggga
     5881 taattgtgtt tctgacgaat tccgacagga ttattggctc catgaatgta accagttgtt
     5941 ttttctaagt ccttttgtgg aatcatgctc acttttttat tgccagaaat tttagctagt
     6001 ttcttttcag acaagtgctg agtgataggg acaattccga taatcggtcc ggtcttgtct
     6061 cccaaaagcg ccaaggtttt gaaaatctga tctcgttcat aaccttgagg aagctctcct
     6121 tctagggcat tgatttgaat cccctgatga gggatagctg ctttagatag gatttgttcc
     6181 accaatgttt ttttgatttt aacttttttt gccattattt atatttatcc tccaattgac
     6241 tcatccaaat accaagccag attcccagcg caaagaagaa ggcgatgatg acataaccga
     6301 caagtgaaag tcctgtgtat tggatacttt cagcgtttcc tgcatttgga attaagatca
     6361 aaagggtact tgataggacg ataccgatga tgaaatgata gacgcgtgag tggtagttgt
     6421 ttaaggcata atccatcaat tttgaaaaaa cgatgagagt tgcacctgca ccaattccaa
     6481 tcggaaagaa ggttcccaag agatcaaaag ttttaaaacc agtcaacata ggagcataga
     6541 gtcccaaaat caaaagtaag ttcgatgggc tgaggccagg aaccaagacg ccaagggcca
     6601 atagtgcgcc tgctaggacg aagttaagaa agctggcgct taaggttcca acgacaaaat
     6661 ttaaggcata gagtcctaat ccagaaatga taaaggttgt ccataaccaa gctaaatcaa
     6721 tcttgtctcg gtcagattct cgagttgatt ctttgaggag gctaggaact gtaccgataa
     6781 tagctcccgc aaagctccat aatacaaaga cctgataatt ttcaagcagg tattcaatcg
     6841 ggtaggaaaa taagccgatt cccagaagca taccgatggc aactggaata aagtacaaaa
     6901 cattttcttt aaggtcttta aagggatggg ccagaaagcc aatcattcgt tcatagattc
     6961 ctaagattgc tgctagaacc cctccggaaa ttcccggtag gataaatcca agagcaatta
     7021 caatcccttt aataacgcgt gctaaccatg agagcatata tttcctccaa ctatttctat
     7081 ttcaaaaatt ccttactata ttgtatcaca atcagacaca aaaagaaaaa gcaaatgata
     7141 aacaaatgct tttaaggttt taaaaaaagt tttcgaaagg tttcttcttt attttttaag
     7201 ggagagataa cgttgatatc taaatcgtgg tcaaagccgg caatttttcc tttagatgtg
     7261 tattggtgaa tatcataatc taaatcagtt ttaggactgc tctccaaaaa tcctgagtct
     7321 gagccgtagg acggaatcca aacagaggta aacttgcctg tatcaatact gtgttcttcc
     7381 atgaagtaga caccaacgta gatgccgatg tttttagcac ctagtgatgc tagttttgct
     7441 cgaaagtttt cgacaccttc gttcatatta gacatggttt tgtcttccac gtcaagccaa
     7501 tagtaactag ggctgtaagg agaggcagca ttgtagaaaa cttcggcagc cttttccatt
     7561 tcttggacac tttttccagc tacataagcg tagacagcaa ctgggacatt ccgcttttga
     7621 agttcagtga tatgactctt ataggccttg tctattccat tgataaatga agcatcattt
     7681 tcttttgttg tttgagcacc actgtgaaca cgaacaatag cacctgaaat attttgtgag
     7741 agggcatcgt agttgatttc ctcaggacgc tgccagccag agaggtcaat aatcggtttg
     7801 tctaagtgtt tcaaagcctg tgcttcaatc tgtgctatat tggattttgt tttaaacgat
     7861 tggctgtcat taagtgggcg attgatgatt aaaatgaaca tcataatccc aaaaaaacta
     7921 aataaaataa gtggatgaat ttgttttctc atatcttata agtctaccct aaaaatcaaa
     7981 aaaaatcaaa aaaatgggtt aaggaagaga ctttagagca ttttttcatt caagagtgcg
     8041 gaatgatttg aaatatggta taataaaagg gaatttctac agaaaagaga agattatgtc
     8101 aaattttgcc attattttag cagcgggtaa agggactcgc atgaaatctg atttgccaaa
     8161 agttttgcac aaggttgcgg gtatttctat gttggaacat gttttccgta gtgtgggagc
     8221 tatccaacct gaaaagacag taacagttgt aggacacaag gcagaattgg ttgaggaggt
     8281 cttggctgga cagacagaat ttgtgactca atctgaacag ttgggaactg gtcatgcagt
     8341 tatgatgaca gaacctatct tagaaggttt gtcaggacac accttggtca ttgcaggaga
     8401 tactccttta atcactggtg aaagcttgaa aaacttgatt gatttccata tcaatcataa
     8461 aaatgtggcc actatcttga ctgctgaaac ggataatcct tttggctatg gacgaattgt
     8521 tcgtaatgac aatgctgagg ttcttcgtat tgttgagcag aaggatgcta cagattttga
     8581 aaagcaaatc aaggaaatca acactggaac atacgtcttt gacaacgagc gtttgtttga
     8641 ggctttgaaa aatatcaata ccaataacgc tcaaggcgaa tactatatta cagacgtcat
     8701 tggtattttc cgtgaaactg gtgaaaaagt tggcgcttat actttgaaag attttgatga
     8761 aagtcttggg gtaaatgacc gtgtggcgct tgcgacagct gagtcagtta tgcgtcgtcg
     8821 catcaatcat aaacacatgg tcaacggtgt tagctttgtc aatccagaag caacttatat
     8881 cgatattgat gttgagattg ctccggaagt tcaaatcgaa gccaatgtta ccttgaaagg
     8941 gcaaacgaaa attggtgctg agactgtttt gacaaacggt acttatgtag tggacagcac
     9001 tatcggagca ggagcggtca ttaccaattc tatgattgag gaaagtagtg ttgcagacgg
     9061 tgtgacagtc ggtccttatg ctcacattcg tccaaattca agtctgggtg cccaagttca
     9121 tattggtaac tttgttgagg tgaaaggatc ttcaatcggt gagaatacca aggctggtca
     9181 tttgacttat atcggaaact gtgaagtggg aagcaacgtt aatttcggtg ctggaactat
     9241 tacagtcaac tatgacggca aaaacaaata caagacagtc attggagaca atgtctttgt
     9301 tggttcaaat tcaaccatta ttgcaccagt agaacttggt gacaattccc tcgttggtgc
     9361 tggttcaact attactaaag acgtgccagc agatgctatt gctattggtc gcggtcgtca
     9421 gatcaataaa gacgaatatg caacacgtct tcctcatcat cctaagaacc agtaggagcc
     9481 tatcatggag tttgaagaaa aaacgcttag ccgaaaagaa atctatcaag gaccaatatt
     9541 taaactggtc caagatcagg ttgaattacc agaaggcaag ggaactgccc gacgggattt
     9601 gattttccac aatggggctg tctgtgtttt agcagtaacg gatgaacaaa aacttatctt
     9661 ggtcaagcag taccgcaaag ctatcgaggc tgtctcttac gaaattccag ccggaaaatt
     9721 ggaagtagga gaaaacacag cccctgtggc agctgccctt cgtgaattag aggaagaaac
     9781 agcctataca gggaaattag aactcttgta cgatttttat tcagctattg gcttttgtaa
     9841 tgagaagtta aaactatatt tagcaagcga tttgacaaaa gtggaaaatc cgcgtccgca
     9901 ggatgaggat gaaaccttgg aagtccttga agtgagctta gaagaagcga aagaattaat
     9961 ccaatcaggt catatctgtg atgccaagac aattatggct gttcagtatt gggagttgca
    10021 gaaaaaatag aggaggtcag tatgggtaaa tctttattaa cggatgaaat gattgaaaga
    10081 gctaatagag gcgaaaaaat ttcaggtcct cctttgctag atgataatga ggaaactaag
    10141 attttaccaa cctcttcttc ccgttttggt tatgccaatc ctaaggatca tggttttagc
    10201 caggaaacct tgaagattca ggtcgaacca tctattcata aaagccgtcg tattgaaaat
    10261 accaagagaa atgtcttcaa ttctaagttg aataaaatct tatttgcggt catctttctc
    10321 ttgattttgc ttgttttagc aatgaaactt ttgtaataga aaaggaattg aaatgaaaat
    10381 aggaattatt gctgctatgc cagaagaact ggcttatctg gtccagcatt tagataatac
    10441 ccaggagcaa gttgttttgg ggaataccta tcatacagga accattgctt ctcatgaagt
    10501 cgttcttgta gaaagtggaa ttggtaaggt catgtctgct atgagtgtgg cgattttggc
    10561 tgatcatttc caggtggatg cccttattaa tacgggttca gctggggcag tagcagaagg
    10621 tatcgctgtt ggggatgtcg tgattgctga caaattagcc tatcatgacg tggatgtcac
    10681 agcttttggc tatgcttatg gacaaatggc gcaacaaccg ctttatttcg aatcagacaa
    10741 aacctttgtt gctcaaatcc aagagagttt atctcaattg gaccaaaact ggcatcttgg
    10801 tttgattgct acaggagata gttttgttgc aggaaatgac aagatagaag cgattaagtc
    10861 ccatttccca gaagttttag ccgtggagat ggagggggca gctattgctc aagcagcgca
    10921 tgccctcaat ctcccagtct tagtcatcag agctatgagt gacaatgcca accatgaagc
    10981 aaacatcttt tttgatgagt ttattatcga agctggacgt cgctctgccc aagtcttgtt
    11041 gacctttttg aaggctttag attaagcgga aatttgacag tttttctagc ttatgataag
    11101 atttaagtaa agaaaagcta gaaaacgttt cagaggatat tatgagtatt gaaatgaccg
    11161 tcagtgagat tgcagaggtc ttaggattat ctcgccaagc aatcaataac cgtgtcaaag
    11221 aattaccaga agaagacaca gataaaaatg acaaaggggt aacagttgtt accagaagtg
    11281 gcttgattaa gctagaagaa atctataaaa aaacgatttt tgaagatgag cctgtcagtg
    11341 aagatgtcaa acaacgtgaa ctgatggaga ttctagtgga tgagaagaat gcagaaattc
    11401 ttcgtcttta tgaacaatta aaagccaagg atcgtcagtt atcagaaaaa gacgagcaga
    11461 tgcgtatcaa agaccgtcag attgctgaga aagacaaaca attagatcag caacaacaat
    11521 tgacccttca agccatgaag gatcaagaaa atcttaagct agagctggac caagcaaaag
    11581 aagaagtcca atccactaag aaaggctttt ttgctcgttt atttggagga taatcaagga
    11641 gctgtttagg ttaaatgcta acctgatggc ttcttttgtt tgtgaatagt atagttgatt
    11701 agaacagaga cagtagagga gaggtacaga atggaacgat tagaagatta cattgctttt
    11761 gacttagaat ttaatcagca cgaaggacaa acacacttga ttcaagtatc ggcagtgcgt
    11821 tttagagatg gtcgggaaat cgatgcctat gattcctatg ttcataccag cgtccctcta
    11881 aaaagcttta tcaatggttt gaccgggatt acagctgaga ccttaaaaga tgctcctcca
    11941 gttgagaaag tcttagaaga attccaagag tttgtgggtt ctttgctgat gataggctac
    12001 aatgctgcta aaagtgattt acctatttta gcagagcatg gtttagacta tagccaacag
    12061 tacaaggtgg atttgtatga tgaagctttt gaacgtcgga gttcagattt acatggtatt
    12121 gccaatctca aattgcaaac tgttgcctca tttcttggat ttcaaggtca gtctcataat
    12181 agtttagagg atgctcggat gacggcgcgt gtttacgaat ccttcttaga gtcggatcaa
    12241 gctagggaat tgttagagac agaaagtagc ttatcaaaca atccttttgg tgtcttggac
    12301 ttgtctcaat tatttgacta ggagtgccta tgaaacctga aaaacctaaa aaattgggtc
    12361 ttaaacagat ttacctcaat cttgataaaa tcctctttct atttttcttg atttttatga
    12421 tagtggagta tttgtgggta ccattcaatt catggttggc tagcttctta ttagatcaga
    12481 caggttatct ttttatttcc tataacaatg tcttagccat ccttactcat tctccattga
    12541 ttagtctagc ttttttagcc ttgattgtaa ttaaccttct ggttgcttat tttcaaatag
    12601 gactcctctt tattggtgct cgtcatctcc tctataatga aaagcgaagg ctaattgagt
    12661 atatccgcaa ggttttccat gaaagttttg gatttatgaa aaagctaact tgcgctaaag
    12721 ccttgtttat ctttttctat atagctatgc tttttccttt tatacggaaa atgctgaaga
    12781 tttattatct taataaaatc gtcattccag agtttatcca agcttattta gaagataaat
    12841 attggatgtg gtggctgagc atcctacttc tatctcttat ctttctctat gtctctgtca
    12901 gattgatgtt tgcccttccg aagattgtat atgatcagct gactgttcga gaagcagtga
    12961 tgtttagctt ggagaaaacc aagaagagag ttacttttta tgcttggaat ttattttaca
    13021 tcttgctcaa agcacattta ttattttatc ttcctttgat tcctttatta ttggctcaaa
    13081 ctttggtaga tgatatcact cagagagagt ctctgattct tggtattttg aattttgtcg
    13141 tgattaaaaa tctctattat atggctctga cttatttttt ggttaaattt gtttcatttt
    13201 tgacaggaaa ggagctggat atgcttccta ggagagaaaa agatcacatc gtgcgatggg
    13261 gtgtcatgac ttgtgccagt cttttctttg ccttagaagg ttatatttat ctggaggctc
    13321 ccatggttca tctacctcaa cttatttctc accgaggggt ttccaatgca aatgggattc
    13381 aaaatacagt agagtccttg gaaactacag cacaactcaa accagacttg gtggagacgg
    13441 acgtgcagga aacaaaagat gggcagtttg tcatgatgca tgatgctaac ttgaaaaatc
    13501 tagcaggtat caataaaagt cctcaagact taaacttgga ggagcttaaa gggattgata
    13561 tttttgaaaa tggctaccag actaaaattt caagctttga agattatctc agtcgagcca
    13621 acgaacttgg tcaaaaatta ctaattgaaa ttaaaaccag taaaaaagat agtccagaca
    13681 tgatgaaccg ctttttagcc cgttatgctg caaagctcaa gatttatgga catcaaatcc
    13741 agtctttaga ctaccatgtt gtcgaaaaag taagacagta tgatgccgaa ctgccagttt
    13801 atttcatcat gccctacaat tctgtctttc ctaaaacaag agcgacagga tatactatgg
    13861 agtactcaac cttggatgaa tattttgtaa gcaaactatg gacaacggat cagaaacttt
    13921 atgtctggac tgtcaatgat tcagaagcta tcagcaaatc tcttcactta ggagtagatg
    13981 gagtgattac agatgatttg gaaaaagttc agcgggaaat agaagtagcc caagaagatc
    14041 cagaatatac ggatttgctc ttgaaaaaag cattggaatt ctttgaattt tagtaataaa
    14101 aaagaggaac ggttgttcct cccatgatag gtaagtattc ttgtgaatgc ttgctttttt
    14161 gtggttgcaa tccgtttacg agaattgttt gtattgttct tgtttcaatt tactttatag
    14221 tgctttgaag ttggaatgct acactataac ttct
//
LOCUS       DAVBDR010000053        14056 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.053, whole genome shotgun sequence.
ACCESSION   DAVBDR010000053 DAVBDR010000000
VERSION     DAVBDR010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14056)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14056)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14056
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.053"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            98..1357
                     /locus_tag="VQ540_001662"
     CDS             98..1357
                     /locus_tag="VQ540_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRZ/ATZ family protein"
                     /protein_id="HET2545433.1"
                     /translation="MKVFQHVNIVTCDQDFHVYLDGILAVKDSQIVYVGQDKPAFLEQ
                     AEQIIDYQGAWIMPGLVNCHTHSAMTGLRGIRDDSNLHEWLNDYIWPAESEFTPDMTT
                     NAVKEALTEMLQSGTTTFNDMYNPNGVDIQQIYQVVKTSKMRCYFSPTLFSSETETTA
                     ETISRTRSIIDEILKYKNPNFKVMVAPHSPYSCSRDLLEASLEMAKELNIPLHVHVAE
                     TKEESGIILKRYGKRPLAFLEELGYLDHPSVFAHGVELNEREIERLASSQVAIAHNPI
                     SNLKLASGIAPIIQIQKAGVAVGIATDSVASNNNLDMFEEGRTAALLQKMKSGDASQF
                     PIETALKVLTIEGAKVLGMENQIGSLEVGKQADFLVIQPQGKIHLQPQENMLSHLVYA
                     VKSSDVDDVYIAGEQVVKQGQVLTVEL"
     misc_feature    1433..1568
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            1607..2107
                     /locus_tag="VQ540_001663"
     CDS             1607..2107
                     /locus_tag="VQ540_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001287276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HET2545434.1"
                     /translation="MSEAIIAKKAELVDVVAEKMKAAASIVVVDARGLTVEQDTVLRR
                     ELRGSEVEYKVIKNSILRRAAEKAGLEDLASVFVGPSAVAFSNEDVIAPAKILNDFSK
                     NAEALEIKGGAIEGAVASKEEILALATLPNREGLLSMLLSVLQAPVRNVALAVKAVAE
                     SKEDAA"
     gene            2183..2551
                     /gene="rplL"
                     /locus_tag="VQ540_001664"
     CDS             2183..2551
                     /gene="rplL"
                     /locus_tag="VQ540_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HET2545435.1"
                     /translation="MALNIENIIAEIKEASILELNDLVKAIEEEFGVTAAAPVAVAAA
                     DAADAGAAKDSFDVELTSAGDKKVGVIKVVREITGLGLKEAKELVDGAPALVKEGVAT
                     AEAEEIKTKLEEAGASVTLK"
     gene            2738..2908
                     /locus_tag="VQ540_001665"
     CDS             2738..2908
                     /locus_tag="VQ540_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001168336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2545436.1"
                     /translation="MQKEGQSSRQFVKSHLMTIMGVDIVKATQLVDEMEQVGLIRFDE
                     FGNVGILVLEGQ"
     gene            2908..3156
                     /locus_tag="VQ540_001666"
                     /pseudo
     CDS             2908..3156
                     /locus_tag="VQ540_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648301.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
     gene            3170..3527
                     /locus_tag="VQ540_001667"
                     /pseudo
     CDS             3170..3527
                     /locus_tag="VQ540_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001134542.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            3520..3900
                     /locus_tag="VQ540_001668"
     CDS             3520..3900
                     /locus_tag="VQ540_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HET2545437.1"
                     /translation="MIDLYLSKNRQRNQLLLDFFQNYGIEVSCHSVSEMTKDKLIEMM
                     SYSSDCFEFLSPNLLRFKNRDNLRLTDFVEIILKNPELTIRLPLAVSNKRVYPSLNLE
                     EARALLPRDTKQLIYMAQTHYLSN"
     gene            3913..4056
                     /locus_tag="VQ540_001669"
     CDS             3913..4056
                     /locus_tag="VQ540_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2545438.1"
                     /translation="MAERFWENLSIILAERNISWIELTRKMFAGEFHYPSELNRLYQK
                     IRH"
     gene            4149..4736
                     /locus_tag="VQ540_001670"
     CDS             4149..4736
                     /locus_tag="VQ540_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000821297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET2545439.1"
                     /translation="MKRIIPVYIFQQVNVLLVSLYLLKFLCIGELTILQILYGSSLIS
                     FLWMYGQRKQAHKVNMKSRMKWLGVEFVSLLIISLCFSLIHAQGSTNQANLIGLQHQI
                     PWFSFLLFLINASMVEEFLYREILWNLVRKLDIRVALTSVLFALAHHTGTILAWCLYV
                     SLGMFLGMVRYKSDLWGSMGLHLVWNLLVYSLLLF"
     gene            4938..5075
                     /locus_tag="VQ540_001671"
     CDS             4938..5075
                     /locus_tag="VQ540_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004264816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SapB/AmfS family lantipeptide"
                     /protein_id="HET2545440.1"
                     /translation="MAEEVLNLQLVSVQVDETDEVDGMRFSTFSTNRCGNWSAFSWEN
                     C"
     gene            5254..7863
                     /locus_tag="VQ540_001672"
     CDS             5254..7863
                     /locus_tag="VQ540_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000386153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lanthionine synthetase"
                     /protein_id="HET2545441.1"
                     /translation="MDYNFNLEHPFFFTNNDYSTDTSIKYQVSLPFNWHEVMNNDEWV
                     YQYPIGKFVERQGWKIHISSEYNSSHELLQDVAKICHEMRIPFKHLSTEDKFIMRNGK
                     LVSRGFSGKFITCYPNQNELESVLQRLESALKQYNGPYILSDKRWDEAPIYLRYGVFR
                     PSRDDEKKVAIDELIVGDEVVKDERLPVFKIPKGIVPPDFLNKWLDKKDKKQGDFPFI
                     IDNAIRFSNSGGIYNARLKEDGKKIILKEARPYTGLGFDGTYSSEKLASECKALKILN
                     EWSETPKIYWHGKIWEHTFLGIEHMKGVPLNRWVTNNFPLYEVVDKTKDYLLRVSKIV
                     EKLIDLTNKFHSENVYHQDLHLGNILVKDEDEISIIDWEQAVFSNDEKVVHKVAAPGF
                     RAWRETLPSEIDWYGIRQIAHYLYMPLVTTSDLTYNYVSQTRIEGKKLFESLGYTREH
                     IDYVESLLSYLDSKCPQIENISRKKVLKPMHEIRTIESEQDIQDFIIKLLRGFTLTYG
                     QWRKEFQSRFFPVHYYGLNFNQGIAFSDLAILWSYQQLAKKVKNFKFDDYYEIRTQVI
                     NEAVNNFKKSSLSGLFDGKIGTIWLIYEFGEIDRAVELFTTHFIEIFENSQNKNLYSG
                     QAGILLVGLYFLSKGEIDNKLGEEILIRLREYTLNYIENPETFCKVGASDVQSNDPYE
                     NFGGLLYGHAGVAWLFGEAYKLTGESIYKNGLELAVDKELVAYKVDSNNSLQYSQGHR
                     LLPYLATGSAGLLLLINRNKEILSSKYLKYLTSLERATDVVFCVLPGLFNGFCGLEVA
                     NNIYSDIDDNFSGQKKLIEQLYRYLCVIEEGFVIAGDNGLKITTDIASGFAGVAIGLV
                     SIMDNKLTILPQI"
     gene            7896..9836
                     /locus_tag="VQ540_001673"
     CDS             7896..9836
                     /locus_tag="VQ540_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S9 family peptidase"
                     /protein_id="HET2545442.1"
                     /translation="MNQSNEIFLNTIQEKTHYKRSISSSFQELKKWNSLIFRRGRYWY
                     QFDNWSIPNTGVIKEWYVEDNDWIPKVSSSSLDNSNSLKIVFDVEKYTLPDDSILQDV
                     RISSDESYIVLVVSSLRSTNLIGIKKYTMEELFIIEDISVESSFYLGKFGVMYTRSKE
                     YGRPSKLFYKSFDSFTEEELFEENECSFRLKIVHIDSNNCFVKSVDFQKGRIFLYSFD
                     RTGFVRHSYTETVAPTPRDIALFSTEKAQYFLGLSSTEEKKDQLILRETSSGDRVSIT
                     IPYQDRARRVHCIGRYILLDCSNAANSVFYLATFKNNSLRELSVNKITFDEKTTLYEN
                     SFSDRVLLFLERRTFYEKILSFDLIENTLKTEFERPIIKSNNTKYFSKVIWTKKDSYD
                     VSIPISLFWKSEDTDELPRRKKCILSVYGAYGKNDNSDLDEIMLSIIDAGFIYAIVHV
                     RGGGYLGGEWYRSGKALNKWNSIRDFIEGVNYLRENDVIDSKRLGLITSSAGGIIAGA
                     VLNEEKNLLQSILLFSPFINPYDTLQNPNDPLSKTEIAEWGDIRDPEVKAYIKSYSPM
                     QNIEKARDSNTVIVNILGEKDPYINNNEVIEWSKKLNSIGVKSLLYLNKAAGHGGFTP
                     SDVLLMIDTLNYFFEEVGRNNL"
     gene            9833..11440
                     /locus_tag="VQ540_001674"
     CDS             9833..11440
                     /locus_tag="VQ540_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2545443.1"
                     /translation="MNYLKFIKKTKLILMGILIFLSSFNGVLLSGIIVYAGSLNQTSS
                     FSDVLRFGAISILGWSAIYISNYYLEVTEASITKDINVKIKQGYFREQYLSSEMVKDY
                     SSIISVLSNDLRLIEENYFRQIFEIISSILLFIVSLSFMLYLNFLVSIIFIVLSALPI
                     IVPVFMKKMLSNSANEYSNSNAEYTHIIKEIFNGFKTLKSYSVTKEIISLSDKKLDKL
                     EDSTFNLKRSEVLSKLVAVLISGFCFLVPLVVGCYFVIYHKSLSFSELIGIFLANDKV
                     LGPIQSIAYSLNKINTTKDLRKPFLKYLSGEKNFIDAEHDNNGLYTSSIDEIHMKDVV
                     YSITPENKLSIDFSFKSPFRVLLTGTSGSGKTTILNLINGSLKPQKGYVNLLSHGKKS
                     SDSIPTVDQTPYIFDTTIRENVTLFQNEYFSDDQIIEVLKKVNLYEELEKIDILNYQC
                     GENGSNLSGGQKQKIALARALIRNNKVYLFDEISANLDNDNSNSIHDILFNLGISFIE
                     VSHHYDLNDKRYTDIYKLENGTLFKIK"
     gene            11455..12195
                     /locus_tag="VQ540_001675"
     CDS             11455..12195
                     /locus_tag="VQ540_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000356590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2545444.1"
                     /translation="MDKDYILKVKGLYHQFLLGNNKTLQVLKNVSLSASRGEFISILG
                     ISGSGKSTLLKCISSLLEPTSGEVILNGINPYKIRNAKLSSIRRNEVSFIFQAYNLIP
                     SLPVIENIALPLRLSQKKLTIKNVENLLKRMKFNAGLNDFVGTLSGGEQQKVAIARAV
                     IADSDIIFADEPTGALDSVSREVIFELLRELVGAGKCVIMVTHDIELASKTDRALILK
                     DGKIFKELHRPSGEELYKILEVQSTTEE"
     gene            12198..13517
                     /locus_tag="VQ540_001676"
     CDS             12198..13517
                     /locus_tag="VQ540_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000945307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2545445.1"
                     /translation="MLRLVYYQFLHNKKQWLGVSPVIFVSSLVMGLAVNGVINVENNS
                     QVFVGLPDPKPIFMFPIVFGGVTLFFVLSNIINMLVEIFRDDYELLEVLGASLLQLSF
                     LVGGQIFIISSIISFIAYLCSIFVTSNYYYFLQYFFGENILPDIQFQTSAVGCIITVV
                     LISFLAFLSGCFYTFKKIRNRKSSKIRHVLSIVKRILLLAGFSVIWLLSLQQIFQDST
                     ILAKAQIIFNIVILDIVIIYQLSPFIQSCFIKLLSIIIFRNNFMFIASKWNLLYRKPY
                     IKSISAAITGAILLISSFQMISQNILSQFQDDSDLELKVAFIVYVGAPILIVLANIIS
                     IAFLSSHQERIEIQQFEILGTSNYQMVKIKVGEAIFLTFVTSLIAFLLNIKIMALIYY
                     SLEDVLIDDMNLLGLILPNFIVSIILFILIFITKSSYFIFKNAKIIS"
     gene            13651..13788
                     /locus_tag="VQ540_001677"
     CDS             13651..13788
                     /locus_tag="VQ540_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004264816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SapB/AmfS family lantipeptide"
                     /protein_id="HET2545446.1"
                     /translation="MAEEVLNLQLVSVQVDETDEVDGMRFSTFSTNRCGNWSAFSWEN
                     C"
BASE COUNT         4696 a         1962 c         2778 g         4620 t
ORIGIN      
        1 agatagaact gacgaagtca gtaaccacac ctacggcaaa gtgaatctga agtggtttga
       61 agagagtaca acttgtcttt tagaaaagga gcctataatg aaagtctttc agcatgtaaa
      121 tatcgtgact tgtgatcaag atttccatgt ttatcttgat ggaatcttag cagtcaagga
      181 ttctcaaatc gtctatgtcg gtcaagataa gccagcgttt ttagagcaag ctgagcagat
      241 tatagactat cagggagctt ggattatgcc tggtttggtc aattgtcaca cccattctgc
      301 aatgacaggt ctgagaggga tccgagatga cagcaatctc catgaatggc tcaatgacta
      361 tatctggcca gcagaatctg agtttactcc cgacatgact accaatgcgg tcaaagaagc
      421 cctgacagag atgctccagt caggaacaac aacctttaac gatatgtata atcccaatgg
      481 tgtggatatc cagcaaattt atcaggtggt gaaaacttcc aagatgcgtt gttatttttc
      541 tccgactctc ttttcttcag agacagaaac aactgctgag actataagca gaactcgatc
      601 catcatagac gaaatcttaa aatataaaaa tccaaatttc aaggttatgg tagcacctca
      661 ttctccgtat agctgcagta gagacttgct ggaagcgagt ttggaaatgg caaaagagct
      721 aaatattccg ctccatgtcc atgtggcgga gaccaaggag gagtcaggaa ttatcctcaa
      781 acgatacggc aaacgccccc ttgcttttct tgaagaactg ggttatttag atcatccgtc
      841 cgtatttgct cacggggtcg aattaaacga gagagaaatt gaacgcttgg catcttctca
      901 agtggctatc gcccacaatc ctatcagtaa cctcaaactg gcatcaggaa ttgctccaat
      961 tatccagatc caaaaagcgg gagtagcagt cggaattgcg actgactcgg ttgcttccaa
     1021 taacaatcta gatatgtttg aggaaggaag gactgcagct cttcttcaga agatgaaaag
     1081 tggggatgcc agccagtttc caatcgaaac agctctcaag gtactgacaa tcgaaggggc
     1141 taaggtcctt ggaatggaaa atcagatagg aagtctggaa gtcggcaagc aagcagattt
     1201 tctggtcatt caaccacaag ggaaaattca tctccaacct caggaaaata tgctgtctca
     1261 cctggtttat gcagttaaat ctagtgatgt agatgatgtt tatatcgccg gagaacaggt
     1321 tgttaagcaa ggtcaagtcc tgacagtaga actttaaaag aaaaatcacg aaaaatttta
     1381 aaaaaagttt gcaaaaatct tgcattcttt ttttgactat gctatactta tatacggttt
     1441 aaaaaaactg cctaagacag taggggagct cgactcataa atatcctacc gaggacaaga
     1501 cgtatcatgt aaaaagaagc gtattgtact ttcgtgtcta ggtttgggcg cgtttttctt
     1561 tttgaaaaat tccccaagca aaataattac ggaggtgaac acactaatga gtgaagcaat
     1621 tattgctaaa aaagcggaac tagttgacgt agtagctgaa aaaatgaaag ctgctgcatc
     1681 tatcgtcgtt gtagacgctc gtggtttgac agttgagcaa gatacagttc ttcgtcgcga
     1741 gcttcgtgga agcgaagttg agtataaagt tattaaaaac tcaatcttgc gtcgtgcagc
     1801 tgaaaaagct ggtcttgaag atcttgcatc tgtatttgtt ggaccatctg cagtagcatt
     1861 ttctaatgaa gatgttatcg caccagcgaa aatcttgaac gacttttcta aaaacgctga
     1921 agcacttgaa attaaaggtg gtgcaatcga aggcgctgtc gcatctaaag aagagattct
     1981 tgcacttgca actcttccaa accgcgaagg acttctttct atgctccttt ctgtacttca
     2041 agcgccagtg cgcaacgttg ctcttgcagt caaagcggtt gcagaaagca aagaagacgc
     2101 ggcttaatct taagctacac agcgtagcct agctacgaaa aaaactatta taaaatttaa
     2161 aacttatttg gaggaaataa caatggcatt gaacattgaa aacattattg ctgaaattaa
     2221 agaagcttca atccttgaat tgaacgacct tgtaaaagct atcgaagaag aatttggtgt
     2281 aactgcagct gctcctgtag ctgttgctgc agctgatgca gctgatgctg gtgctgctaa
     2341 agattcattc gacgttgaat tgacatctgc aggcgacaaa aaagttggcg ttatcaaagt
     2401 tgtacgtgaa atcactggtc ttggtcttaa agaagctaaa gaacttgttg acggtgcacc
     2461 agcacttgtt aaagaaggcg ttgcaactgc agaagctgaa gaaatcaaaa ctaaattgga
     2521 agaagctgga gcttcagtta ctcttaaata atagagtatc gcaatttgat tgcggaatcc
     2581 ctatttacca gtctttgaga gcgataagcg attgatagaa actgataaat tgatttggtt
     2641 tcctgccaaa aattctttgg caggattttt gttttaataa actttcgggg gtagacacta
     2701 gattgtctac cccttttttt gtgtttcgga ggtaattatg caaaaggaag gacagtcatc
     2761 acgtcaattc gtgaagagtc atctcatgac tatcatggga gttgatattg taaaagcaac
     2821 tcagttagtt gatgaaatgg aacaagtagg tttaatccga tttgatgaat ttggaaatgt
     2881 tggaatttta gtcttggagg gacaataatg aagtgtatta ccgctaatca atatcagaca
     2941 tcagagcgtt attataagct ccccaaactt ttatttgaga gtgaacggta taagaatatg
     3001 aaactggagg ttaaggtggt ttactcagtt ttaaaagatc ggttggagtt gtctttgagc
     3061 aaaggttgga ttgatgagga tggggctatt tatttgattt attccaattc aaatttgatg
     3121 gcacttttag gctgttcaaa gtcaaaatta ctctccatgt gagtttgaag tgacattttt
     3181 agatgattac cataaaaaac ataactaccc actattttac gaatcctatc ttcaaaacgt
     3241 tatggaattc cttgaaagtc aagacataaa gaatggggtt gatgcctttg tagatgatca
     3301 tcaaaatctc gtttttgttt tatatggaca aggctatcga gccgagggaa aagagggaat
     3361 acttacaacc caagtaactg taaaagctta tgatgaagac aagaaaccga ttaacttcgc
     3421 aaatttatta gattccttaa tttattagat tccttaattt attagattcc ttaatcgtgt
     3481 cagaatatca aatggaaccg aatctttggg aggtctccca tgattgatct ctatctaagt
     3541 aaaaatagac aaagaaatca acttctttta gatttcttcc aaaactatgg catagaggta
     3601 tcttgtcatt cagtttctga aatgacaaag gacaaattaa ttgagatgat gagctattct
     3661 tcagattgtt ttgagttttt atctcccaat ttattacgat ttaagaaccg tgacaatcta
     3721 agattaacgg atttcgttga gataatttta aaaaatcctg aactaaccat cagacttcct
     3781 cttgcggttt caaataagcg agtttatcca agtctgaatt tggaagaggc tagagctcta
     3841 ttgccaagag atacgaaaca attgatttac atggcgcaaa cacattattt atctaactaa
     3901 aggagaagca atatggctga acgattttgg gagaacttgt ccattatttt ggctgaaaga
     3961 aatatcagct ggattgagtt aaccagaaaa atgtttgcgg gagagtttca ctatccaagt
     4021 gaattgaatc gtttgtatca aaagattcgc cactagaaga tggaacaatg aatgcctcaa
     4081 agtccatggg tagaaaggat tgtgcaggta ttagatttag attatgaaga tttatttcgg
     4141 aggtaactat gaaaagaata attccagttt atatattcca acaagtaaat gtcctattgg
     4201 tatctctata cttattgaaa tttctttgta tcggtgagtt aactatacta cagattctct
     4261 atggttcgtc actcatttct tttttatgga tgtatggcca acgcaaacaa gcgcataagg
     4321 tcaatatgaa atctaggatg aaatggcttg gtgttgaatt tgttagccta ctgattataa
     4381 gtctatgttt tagtctgatt catgctcaag gaagcacgaa tcaagcaaac ttaattggcc
     4441 ttcaacatca aattccttgg ttttcatttt tattgttctt aatcaatgcg agtatggttg
     4501 aagaatttct gtatcgagaa attttatgga atttggtcag aaaattagat atcagagttg
     4561 ctttgacaag tgttttattt gccttagcac atcatacagg aaccattcta gcttggtgtt
     4621 tgtatgtttc acttgggatg tttttaggta tggtgcgcta taaatctgac ttatggggca
     4681 gtatgggact acatttggtg tggaacctac tagtttatag tttgctgctt ttttaaaata
     4741 ggtgacctga tttttaggta acttctaaaa ctaacttcca gttttgggag agagatggaa
     4801 gttactttga aaagttacgg aaacattatt ttctatgtga caacattgta taattgcttg
     4861 cattttactg gtggagagag tataatgagg gtggataaag tacttaatcc caaaaattta
     4921 aataggagga gctagctatg gcagaagaag tattaaatct tcaattagta tctgttcaag
     4981 ttgacgaaac agatgaagtt gatggaatgc gatttagtac attcagtaca aatcgttgcg
     5041 gtaactggag tgcttttagt tgggaaaatt gttaattcat ttaaattgta aactttagag
     5101 attctctgga gttatggatg tcgttccaat atgtgcacgt tggaatgtta gtgcttatat
     5161 ggggagaatc caaaggattc tcccttttta tttaaataag tctgtctagc tatagatata
     5221 ttaagtttga taaaatttct tggagatttt gttatggatt ataatttcaa tttggagcat
     5281 cctttctttt tcactaataa tgattatagt acagatacta gcataaagta ccaagtaagt
     5341 ctgcctttta attggcacga agtaatgaat aatgatgagt gggtttatca ataccctatt
     5401 ggaaaatttg ttgaaagaca agggtggaaa atacacatta gttcagagta taacagttca
     5461 catgaattgt tacaagatgt agcaaaaatt tgccatgaaa tgcgaattcc atttaaacat
     5521 cttagtacag aagacaaatt tatcatgcga aacgggaaat tggttagtcg aggattttct
     5581 ggtaaattta ttacatgtta tccaaatcaa aatgaattag agtcggtttt gcaaaggtta
     5641 gaaagtgcct taaagcaata taatgggcca tatattttaa gcgataaacg ttgggatgaa
     5701 gcaccaatat atctgaggta tggtgtgttt aggccgtcaa gggatgatga aaagaaggtt
     5761 gctattgatg aattaattgt tggcgatgaa gttgttaaag atgaacgttt accagtattt
     5821 aaaattccaa aaggtatagt gccccctgac tttttgaata aatggcttga caagaaagat
     5881 aaaaaacagg gagactttcc ctttattata gataatgcaa ttagattttc aaacagtggt
     5941 gggatatata atgctaggct aaaagaagat gggaaaaaaa taattttaaa agaggctaga
     6001 ccgtatacag gtctaggatt tgatggtact tattcttcag agaaattagc ttcggagtgc
     6061 aaagcactaa aaattctaaa tgaatggagt gagacgccta aaatatactg gcacggtaag
     6121 atctgggagc acaccttctt aggaattgaa catatgaagg gcgttccact aaatagatgg
     6181 gttaccaata attttccttt atatgaagtt gttgataaga ccaaagatta tctattgaga
     6241 gtttcaaaga tagtagaaaa actcatcgat ttaacgaata agtttcattc tgaaaatgta
     6301 tatcatcaag atttacattt aggaaatatc ttggttaagg atgaagatga gattagtata
     6361 atagactggg aacaggctgt cttttcaaat gatgaaaaag ttgtacataa agttgcagcc
     6421 cctggtttta gagcatggcg agaaacactt cccagtgaga tagattggta tggtattaga
     6481 caaatagctc attatttata catgccacta gtaactacat cggatttgac atacaactat
     6541 gtaagtcaaa ccaggataga aggaaaaaaa ctatttgagt ctttgggtta tacaagagaa
     6601 catatagatt atgtagaaag tttattgtca tatctagatt ctaaatgtcc acagattgag
     6661 aatatttcca ggaaaaaagt tttaaaaccc atgcatgaga ttagaactat cgagagtgag
     6721 caagatatac aagattttat tataaaatta ttgagagggt ttacgctaac ttatggacag
     6781 tggcgtaaag aatttcaatc aagattcttc ccagttcatt attatggtct gaattttaat
     6841 caaggaattg cgttttcaga tttagctatc ctttggagtt atcaacaact agctaagaaa
     6901 gtaaaaaatt tcaagtttga tgactattat gagattcgaa cacaggttat taatgaggca
     6961 gtaaataatt ttaagaaatc gtccctttct ggtctttttg atggtaaaat tggtacaatc
     7021 tggctcattt atgaatttgg ggagatagat cgggcagttg aactttttac aactcatttt
     7081 atagagatat ttgagaattc acaaaataaa aatttatata gtgggcaggc tggaatttta
     7141 ctggttggac tgtattttct tagtaaaggg gaaattgata ataaactagg agaagaaata
     7201 ctaattaggc ttagagaata tactttaaat tatatagaaa atccagaaac tttttgtaaa
     7261 gttggcgcta gtgatgttca gagtaatgat ccttatgaga attttggtgg attactatat
     7321 ggtcacgcag gggtagcttg gctcttcggt gaagcttata aattaactgg tgaaagtatc
     7381 tataaaaatg gtctagaatt ggctgtagat aaagaattag ttgcttataa agtagatagt
     7441 aataattcat tgcagtacag ccaaggtcat agattactac catatctagc aactggaagt
     7501 gctggcctgc ttttacttat taatagaaat aaagaaatct tgtcaagcaa atacttaaaa
     7561 tatttaactt ctttagagag ggcaactgat gtagtttttt gtgtattacc aggtttattt
     7621 aacggatttt gtggtcttga agttgctaat aatatatata gtgatatcga tgataacttt
     7681 tcaggacaaa agaaattaat tgaacaactt tatagatatt tgtgtgtaat tgaagaagga
     7741 tttgttattg cgggagataa tggtttaaag ataacaacag atattgcttc gggatttgcg
     7801 ggtgttgcaa ttggattggt atcaataatg gataataaat tgacgattct tcctcaaata
     7861 taatatttag ataccattat taaggggtca tacttgtgaa tcagagtaat gaaatatttt
     7921 taaatacaat acaggaaaaa acacactata agaggtctat ctcttcatca tttcaggaat
     7981 taaaaaaatg gaattctttg atatttagga gagggcgata ttggtaccaa tttgataatt
     8041 ggagtatacc caatactggt gtaataaagg aatggtatgt cgaagataat gactggattc
     8101 ctaaggttag ttcttccagt ttagacaatt caaattcact taaaattgtc tttgatgtgg
     8161 aaaaatatac tttgccagat gatagtatct tacaggatgt taggatttca tctgatgaga
     8221 gttatatagt tttggttgta tcctcactgc gtagcactaa tttaattgga ataaaaaaat
     8281 atactatgga agagttattt atcattgaag atatttcagt agaaagttcg ttctatttgg
     8341 gtaaattcgg tgttatgtat actcgctcca aagagtacgg gaggccaagt aagttattct
     8401 ataaatcttt tgatagcttt acagaagagg aactgtttga agaaaacgaa tgctcttttc
     8461 gattaaaaat agtccacatt gatagcaata attgttttgt aaagtcagta gactttcaga
     8521 aaggcaggat ttttctatac agtttcgacc ggacgggttt tgttagacac tcttacacag
     8581 aaacggtagc cccaacacct agagatatcg ctctatttag tacagaaaaa gcacagtact
     8641 ttcttgggct ctcttcaact gaagaaaaga aagatcaact aattctaagg gaaacttctt
     8701 cgggagacag agtttctatt actataccat atcaagatag ggctagaaga gttcactgta
     8761 taggacgtta tatcctttta gactgttcaa acgcagcgaa ttccgtcttt tatcttgcta
     8821 catttaaaaa taatagtttg agggagttga gtgttaataa gataacattt gatgaaaaga
     8881 caacacttta tgaaaattca ttttctgatc gtgttcttct gtttttagag aggagaactt
     8941 tttacgaaaa aatacttagt tttgatttaa tagaaaatac attaaaaact gaatttgaaa
     9001 gacccatcat aaaatcgaat aatactaaat atttttctaa ggtgatttgg actaaaaaag
     9061 acagttatga tgtaagcata ccgatttctt tattttggaa aagtgaagat acggatgagc
     9121 tcccaagaag aaaaaaatgt attctaagtg tctatggggc ttatggtaag aatgataatt
     9181 ctgatttaga tgaaattatg ttatctataa tagatgcagg ttttatttat gctatagttc
     9241 atgtaagagg tggaggctat ttgggtggtg aatggtatcg ctcaggaaag gcgttaaaca
     9301 aatggaattc tatcagagat tttattgagg gagtaaatta tttaagggaa aatgatgtaa
     9361 ttgacagtaa gcgattaggt ttaataactt ctagtgcagg tggaataatt gctggtgcgg
     9421 tgttgaacga ggaaaaaaat ttattgcaaa gcattctctt attttcgcca tttataaatc
     9481 cttatgatac acttcagaat ccaaatgatc ctctttctaa gaccgaaata gcagagtggg
     9541 gagatattag agaccctgaa gtaaaggctt atataaagtc atattcgcct atgcaaaata
     9601 ttgaaaaggc acgagactca aatactgtta tagttaatat tttgggtgag aaagacccat
     9661 atattaataa taacgaagtg atagagtggt caaagaaatt aaattctatt ggagttaaaa
     9721 gtttgttgta tttaaacaaa gcagctggtc atggaggttt tactccatca gatgttctct
     9781 taatgattga tactttaaat tatttctttg aagaagtggg aaggaataac ttatgaatta
     9841 tttaaaattt ataaaaaaga ctaaacttat attaatgggg attttaatat ttctatcttc
     9901 gtttaatggt gtcttgctct caggaattat tgtatatgca ggtagtttaa atcagacttc
     9961 ctcattttct gacgttctaa gatttggtgc tataagtatt ctgggttggt cagcaatcta
    10021 tatatcaaat tactatttag aagtaacgga agcatcaata acgaaagata taaatgtaaa
    10081 aattaaacaa ggatatttta gagaacagta tctttcttct gaaatggtta aagattactc
    10141 atctattatt tcagttttgt caaatgattt gagattaatc gaagaaaact attttagaca
    10201 aatttttgaa ataatttctt caatattgtt gttcatcgtc tctctaagtt ttatgcttta
    10261 tttaaacttc ctagtttcaa taatatttat tgtattatca gcattgccga ttatagtacc
    10321 tgtctttatg aagaagatgt tgtctaattc agctaatgag tactctaaca gcaatgcaga
    10381 gtatactcac ataataaaag aaatttttaa tggttttaag acattaaaat cttattctgt
    10441 tactaaagaa ataattagtt tgtcggataa aaagttggat aaactagaag attctacttt
    10501 taatttgaaa cgatcagagg ttctttcaaa attggttgca gtactaattt caggtttttg
    10561 ctttctagtt cccttggttg taggatgtta ttttgtaatt tatcataaaa gcctttcttt
    10621 tagtgaactg ataggtattt tcttagcaaa cgataaagtt ttagggccga tacaatcaat
    10681 tgcctattca ttaaataaga taaatacaac caaagattta aggaaaccgt ttttaaaata
    10741 cttaagtgga gagaagaatt ttatagacgc tgaacatgat aataacggac tgtatacttc
    10801 atcaatagat gagatacaca tgaaagatgt tgtatattct attacaccag aaaataaatt
    10861 aagtattgac ttctcattta agtcaccatt tagggtatta ttaacaggaa cttctggtag
    10921 tgggaaaaca acgattttaa atttaattaa tggttcttta aagccacaaa aaggttatgt
    10981 aaatttgtta tcacatggga aaaagagttc agattcaata ccaacagttg atcagacacc
    11041 atatattttt gacactacta ttcgtgagaa cgtaacttta tttcaaaatg aatatttttc
    11101 agatgatcag ataattgagg tgttaaaaaa ggtaaatcta tatgaagaat tagaaaagat
    11161 agatatacta aattatcaat gtggtgaaaa tggtagtaat ttgtctggag gtcaaaaaca
    11221 aaaaatagct ttagctagag ctctgattag aaataataaa gtgtacttat ttgacgaaat
    11281 atcagctaat ttagataatg ataattcaaa ttccatacat gatattctgt tcaatttagg
    11341 tatttcattt attgaagttt cacatcatta tgacttaaat gacaagagat acactgatat
    11401 atataaattg gaaaatggaa cacttttcaa aattaagtga ttggaggcaa gaatatggat
    11461 aaagattata tattaaaagt gaaagggctg tatcatcaat ttttactagg aaataataaa
    11521 acgttgcaag tgctgaaaaa tgtttctctt tctgcttcga gaggagaatt tataagtatt
    11581 ctaggaatta gtggttctgg aaagtcaact ttattaaaat gtatttctag tttgcttgaa
    11641 ccaacaagtg gggaagtaat tttaaatgga atcaacccct ataaaatcag aaatgcaaaa
    11701 ttgtcaagta taagacgtaa cgaagtatct tttatatttc aagcatacaa tttaatacct
    11761 tccctgccgg taatagaaaa tatagcactt cctttgcgat tatcacaaaa aaaattaact
    11821 attaaaaatg tagaaaactt actcaaaaga atgaagttta atgctggctt aaacgatttt
    11881 gttggaactc tgtctggtgg agaacaacag aaggttgcta tagctagagc ggttattgct
    11941 gatagtgata taatatttgc tgatgagcca actggggctt tagacagcgt ttctcgtgaa
    12001 gtaatttttg aattattgag agagttagta ggggcgggta agtgtgtaat tatggtaacg
    12061 cacgatatag aattggcctc gaaaactgat cgtgcattaa tattgaaaga tggaaaaatt
    12121 ttcaaagaac ttcatagacc tagcggggaa gagttgtata aaatcttaga ggtacaatca
    12181 actacggagg aatagagatg ctcagattag tttactatca atttttacat aataagaaac
    12241 aatggttagg cgtttcacca gtaatttttg tttcgagttt agttatggga ttggctgtta
    12301 atggggtaat taatgttgag aataattcgc aagtatttgt cggacttcca gatcctaaac
    12361 caatttttat gtttccgata gtattcggag gagtaacatt attctttgtg ctctctaaca
    12421 taataaatat gttggttgaa atttttagag atgattacga acttctggag gtgttgggag
    12481 caagtctcct tcaactatca tttcttgtgg ggggacagat ttttatcatt tcctcgatta
    12541 ttagttttat tgcatatcta tgctctatat ttgttacgtc aaattattat tattttttac
    12601 aatacttttt cggggaaaat atattacctg atatccaatt tcaaacgagt gctgttggat
    12661 gtatcattac agtagtgttg atttcatttt tagcctttct aagtggttgc ttttatacgt
    12721 tcaagaagat tagaaatagg aagagttcta aaataaggca tgttctttca atagtaaaaa
    12781 gaatactgct attggctggt tttagtgtta tctggttgct ttctttgcaa caaattttcc
    12841 aagatagcac aattttagcg aaggcccaga taatattcaa tattgtaatc ttagatattg
    12901 tgattattta tcaattatct ccttttatac agtcatgttt tatcaaacta ctttctataa
    12961 ttatatttag aaataatttt atgttcattg cttcgaagtg gaatttacta tatcgtaagc
    13021 cttatataaa atctatcagt gctgcaatta caggagctat attactaatt tctagttttc
    13081 aaatgatttc tcagaatata ctatctcaat ttcaagatga cagtgattta gagctaaaag
    13141 tggcatttat tgtctatgta ggagcaccaa ttttgatagt acttgcaaat attatttcaa
    13201 ttgcattttt gtcatcgcat caagaaagga ttgagattca gcaatttgaa attttaggaa
    13261 cttctaatta ccagatggtt aagattaaag ttggtgaggc tatatttttg acatttgtta
    13321 cttcattaat tgcattttta cttaacatta aaattatggc tttaatatac tactctttag
    13381 aggatgtttt aatagatgat atgaatcttt tggggttaat acttccaaat tttatagtgt
    13441 ctattatttt atttatttta atatttatta ctaaaagttc ctattttatc tttaagaatg
    13501 caaaaattat ttcttaaaaa tttgtaagtt ttcgctatat aaaatagtta aatctatttt
    13561 gtatcattgc ttgcatttta ctggtggaga gaatataatg agggtggata aagtacttaa
    13621 tcccaaaaat ttaaatagga ggagctagct atggcagaag aagtattaaa tcttcaatta
    13681 gtatctgttc aagttgacga aacagatgaa gttgatggaa tgcgatttag tacattcagt
    13741 acaaaccgtt gcggtaactg gagtgctttt agttgggaaa attgttaatt catttaaatt
    13801 gtaaacttta gggattctct gaagttatgg atgtcgttcc aatatgtgta cgttggaatg
    13861 ttagtgctta tatgggggga acagaatcct ctcttgattg aagacaagtt agccattagg
    13921 ctggtttgtc tctttgtcaa ctgtagtggg ttgatataat agtattagtg agtgggataa
    13981 aagtttcatt tagtttattc agtacaaatt taacgggtca agatttattg aactgcaccc
    14041 caatagttag acagaa
//
LOCUS       DAVBDR010000054        14013 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.054, whole genome shotgun sequence.
ACCESSION   DAVBDR010000054 DAVBDR010000000
VERSION     DAVBDR010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14013)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14013)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14013
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.054"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            complement(122..1972)
                     /locus_tag="VQ540_001678"
     CDS             complement(122..1972)
                     /locus_tag="VQ540_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HET2545447.1"
                     /translation="MNKKLTDYVIDLVEILNKQQKQVFWGIFDIFSMVVSIIVSYILF
                     YGLINPAPVDYIIYTSLAFLFYQLMVDFWGLSASISRYSKITDFMKIFFGVTASSVLS
                     YSICYAFLPLFSIRFIILFILLSTFLILLPRITWQLIYSRRKKGSGDGEHRRTFLIGA
                     GDGGALFMDSYQHPTSELELVGILDKDSKKKGQKLGGIPVLGSYDNLPELAKRHQIER
                     VIVAIPSLDPSEYERILQMCNKLGVKCYKMPKVETVVQGLHQAGTGFQKIDITDLLGR
                     QEIRLDESRLGAELTGKTILVTGAGGSIGSEICRQVSRFNPERIVLLGHGENSIYLVY
                     HELIRKFQGIDYVPVIADIQDYDRLLQVFEQYKPAIVYHAAAHKHVPMMERNPKEAFK
                     NNIRGTYNVARAVDEAKVPKMVMISTDKAVNPPNVMGATKRVAELIVTGFNQRSQSTY
                     CAVRFGNVLGSRGSVIPVFERQIAEGGPVTVTDFRMTRYFMTIPEASRLVIHAGAYAK
                     DGEVFILDMGKPVKIYDLAKKMVLLSGHTESEIPIVEVGIRPGEKLYEELLVSTELVD
                     NQVMDKIFVGKVNVMPLESINQKIGEFRTLSGDELKQAIIAFANQTTHIE"
     gene            complement(2040..3179)
                     /locus_tag="VQ540_001679"
     CDS             complement(2040..3179)
                     /locus_tag="VQ540_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HET2545448.1"
                     /translation="MSSKVSGFQDKNGKVLKIMIEWWKGKFRRVVVTQNVESLLVSIV
                     ISAYNEEKYLPGLIEDLKNQTYPKENIEILFINAMSTDGTTAIIQQFIKEDAEFNSIR
                     LYNNPKKNQASGFNLGVKHSVGGLILKIDAHSKVTESFVMNNVAVIQQGEFVCGGPRP
                     TIVKGKGKWAETLHLVEENMFGSSIANYRNSSEDRYVSSIFHGMYKREVFQKVGLVNE
                     QLGRTEDNDIHYRIREHGYKIRYSPSILSYQYIRPTFKKMLHQKYSNGLWIGLTSHVQ
                     FKCLSLFHYVPCLFVLSLVFSLALLPITFVFITLLLGAYFLLLSLLSLLTLLTLLKHK
                     NGFLIVMPFLLFSIHFAYGLGTIVGLIRGFKWKKEYKGTVIYLEK"
     gene            3237..4403
                     /locus_tag="VQ540_001680"
     CDS             3237..4403
                     /locus_tag="VQ540_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CynX/NimT family MFS transporter"
                     /protein_id="HET2545449.1"
                     /translation="MKKQSLFFVPGIILIGVSLRTPFTVLPIILGNISQGLEVEVSSL
                     GVLTSLPLLMFTLFSPFSTRLAQKIGLEHLFTYSLFFLTIGSLIRLINLPLLYLGTLM
                     VGASVAVINVLLPSLIQANQPKKIGFLTTLYVTSMGIATALASYLAVPITQASSWKGL
                     ILLLTLLCLATFLVWLPNHRYNHRLAPQTKQKSQIKVMRNKQVWAIIIFSGFQSLIFY
                     TAMTWLPTMSIHAGLSSHEAGLLTSILSLISIPFSMTIPSLTTSLSTRNRQLMLTLVS
                     LAGVVGISMLFFPINNFIYWLAIHLLIGTATSALFPYLMVNFSLKTSAPEKTAQLSGL
                     SQTGGYILAAFGPTLFGYSFDLFHSWVPAVAALLLIDILMTVALFTVDRADKIL"
     gene            4542..4868
                     /locus_tag="VQ540_001681"
     CDS             4542..4868
                     /locus_tag="VQ540_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HET2545450.1"
                     /translation="MYFPTSSALIEFLILAVLEQGDSYGYEISQTIKLIANIKESTLY
                     PILKKLEGNSFLTTYSREFQGRMRKYYSLTNGGIEQLLTLKDEWTLYTDTINGIIEGS
                     IRHDKN"
     gene            4855..5448
                     /locus_tag="VQ540_001682"
     CDS             4855..5448
                     /locus_tag="VQ540_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000198695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HET2545451.1"
                     /translation="MTRTEYLTQLELYLKKLPEADRIEAMDYFRELFDDAGVEGEEEL
                     IASLGTPKEVAHEVLSNLLDKKINEAPAQKNNRQILHIALLALLAAPIGIPLGIAILV
                     TLFAILVAALTVILAFFAVSILGIIGGFLFLVESFTVLAQAKSAFILIFGSGLLAIGA
                     SSLVLLGISYVARFFGLLIVRLVQFVLKKGKRGNQHA"
     gene            5441..6352
                     /locus_tag="VQ540_001683"
     CDS             5441..6352
                     /locus_tag="VQ540_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001233690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 domain-containing protein"
                     /protein_id="HET2545452.1"
                     /translation="MRKWTKGFLIFGVVTTVIGFILLFVGIQSDGIKSLLSMSKEPVY
                     DSRTEKLTFGKEVENLEITLHQHTLTITDSFDDQIHISYHPSLSAHHDLITNQNDRTL
                     SLTDKKLSETPFLSSGIGGILHIASSYSSRFEEVILRLPKGRTLKGINISANRGQTTI
                     INASLENATLNTNSYILRIEGSRIKNSKLTTPNIVNIFDTVLTDSQLESTENHFHAEN
                     IQVHGKVELTAKDYLRIILDQKESQRINWDISSNYGSIFQFTREKPESRGTELSNPYK
                     TEKTDVKDQLIARSDDNIDLISTPSRR"
     gene            6415..7479
                     /locus_tag="VQ540_001684"
     CDS             6415..7479
                     /locus_tag="VQ540_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2545453.1"
                     /translation="MKQEWFESNDFVKTTSKNKPEEQAQEVADKAEETIADLDTPIGK
                     NTQVEEEVSQAEVELESQQEEKIETPEGGEARTEIEEKKASNSTEEEPDLSKETEKVT
                     IAEESQEALPQQKATTKEPLLISKSLESPYIPDQAPKSRDKWKEQVLDFWSWLVEAIK
                     SPTSKLETSITHSYTAFLLLILFSASSFFFSIYHIKHAYYGHIASINSRFPEQLAPLT
                     LFSIISILVATTLFFFSFLLGSFVVRRFIHQEKDWTLDKVLQQYSQLLAIPIFLTAIA
                     SFFAFFDSLRFTALLCVISIGIILLASLHIITRPSQASETDSFYQLFLSVLVNGVIIL
                     LFFVAEVALIGDYLRILAFL"
     gene            complement(7551..8411)
                     /locus_tag="VQ540_001685"
     CDS             complement(7551..8411)
                     /locus_tag="VQ540_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4299 domain-containing protein"
                     /protein_id="HET2545454.1"
                     /translation="MAKTFFIPNKQSILGEQEILNAKSILALLDGLESHIYDVVYLRQ
                     PLNRLEYIECAIVGQSQFLFKVSYADGQKAYRVDLPDLLTETDWQIIKSFLDALLAYT
                     GTDIEGLDGFDFEAYFQASIQAYLADPVARFTICQGIFNPIFFSRENLKSFLEADGLA
                     QFEARVRAVQETDAYFARVSFYQDGEGKVHGVYHLAQGVKTVLPREPFVPAAYIEQLV
                     DKEVQWEIDLVQITGDGSKPEDYEAIARLDYAKFLEVLPPSFYHQLDANQIEVQPILD
                     KDFKTLAQEK"
     gene            complement(8533..9519)
                     /locus_tag="VQ540_001686"
     CDS             complement(8533..9519)
                     /locus_tag="VQ540_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HET2545455.1"
                     /translation="MAKDIRVLLYYLYTPIENAEQFAADHLAFCKSIGLKGRILVADE
                     GINGTVSGDYETTQKYMDYVHSLPGMEELWFKIDEENEQAFKKMFVRYKKEIVHLGLE
                     DNDFDNDINPLETTGAYLSPKEFKEALLDKDTVVLDTRNDYEYDLGHFRGAIRPDIRN
                     FRELPQWVRDNKEKFMDKRVVVYCTGGVRCEKFSGWMVREGYKDVGQLHGGIATYGKD
                     PEVQGELWDGKMYVFDERIAVDVNHVNPTIVGKDWFDGTPCERYVNCGNPFCNRRILT
                     SEENEDKYLRGCSHECRVHPRNRYVSKNELTQAEVIERLAAIGESLDQAATV"
     gene            complement(9791..11266)
                     /locus_tag="VQ540_001687"
     CDS             complement(9791..11266)
                     /locus_tag="VQ540_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3502 domain-containing protein"
                     /protein_id="HET2545456.1"
                     /translation="MKNWKKYAFASASVVALAAGLAACGNLTGNSKKAADSGDKPVIK
                     MYQIGDKPDNLDELLANANKIIEEKVGAKLDIQYLGWGDYGKKMSVITSSGENYDIAF
                     ADNYIVNAQKGAYADLTELYKKEGKDLYKALDPAYIKGNTVNGKIYAVPVAANVASSQ
                     NFAFNGTLLAKYGIDISGVTSYETLEPVLKQIKEKAPDVVPFAIGKVFIPSDNFDYPV
                     ANGLPFVIDLEGDTTKVVNRYEVPRFKEHLKTLHKFYEAGYIPKDVATSDTSFDLQQD
                     TWFVREETVGPADYGNSLLSRVANKDIQIKPITNFIKKNQTTQVANFVISNNSKNKEK
                     SMEILNLLNTNPELLNGLVYGPEGKNWEKIEGKENRVRVLDGYKGNTHMGGWNTGNNW
                     ILYINENVTDQQIENSKKELAEAKESPALGFIFNTDNVKSEISAIANTMQQFDTAINT
                     GTVDPDKAIPELMEKLKSEGAYEKVLNEMQKQYDEFLKNKK"
     gene            complement(11370..12293)
                     /locus_tag="VQ540_001688"
     CDS             complement(11370..12293)
                     /locus_tag="VQ540_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001075101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HET2545457.1"
                     /translation="MAKKKIKKEKIDNVGIHSFSKKADIFFSIISGLIALSCILPFVF
                     VIIISVTDEKSLLQYGYSFFPSQFGLDGFEFLAQFKDKILQALFISVFVTVVGTLTNV
                     FITTTYAYAISRTTFKYRRFFTIFVLLSMLFNAGLVPGYIMVTRVLQLGDTVWALIVP
                     MLLSPFNIILMRSFFKKTIPEAILESARIDGASEARIFFQICLPLSLPGIATITLLTA
                     LGFWNDWFNALLYIKSDNLYPLQYLLMQIQQNMDYIAKAVGLTGQLGVALPKETGRMA
                     MVVVATLPIAILYPFFQRYFVKGLTIGGVKE"
     gene            complement(12307..13236)
                     /locus_tag="VQ540_001689"
     CDS             complement(12307..13236)
                     /locus_tag="VQ540_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET2545458.1"
                     /translation="MKKFSKTLRDNWIFLLMVLPGALWLILFFYIPVFGNVVAFKDYH
                     MTSNGFIDSIINSKWVGLDNFRFLFSSRDAFIITRNTVLYNLGFIFLGLVVSVGIAII
                     LSELRSKRMVKIFQTSMLFPYFLSWVIISFFTDAFLNIDKGVFNHLLESLGLKEVNFY
                     ADLGIWPYLLLFLGIWKGFGYSSVMYYATIMGIDPTYYEAATVDGASKWQRIRNVTIP
                     QLTPLVTVLTILAVGNIFRADFGLFYQIPHNAGQLYNVTNVLDVYVFNGLTQTADIGM
                     AAAAGLYQSVVGLILVILSNLLARRVDPNSALF"
     gene            complement(13555..13905)
                     /locus_tag="VQ540_001690"
     CDS             complement(13555..13905)
                     /locus_tag="VQ540_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2545459.1"
                     /translation="MTGVSNPTTDSARLVLAEAKKAFADDSLTEQGLRDILQTVKDAI
                     ASLESIKESQSATKDGGQTAGKETADKDVLENSQEELQKAVLFLADEKGSEHTEAELI
                     DNLKEVIAKLKANA"
BASE COUNT         4190 a         3027 c         2582 g         4214 t
ORIGIN      
        1 aaccatatac ggcaaggcga cgttgacgtg atttgaagag attttcgaag agtataagtc
       61 tctacataat aaaacgcata ttaccaaggt tatttaactt gataatatgc gtttttcttt
      121 tttattcaat gtgggttgtt tgattagcaa aggcgataat agcttgcttc aactcatctc
      181 cactgagagt gcggaactct ccaatctttt gattgatgga ttctaaaggc atgacattaa
      241 ccttaccaac gaaaatctta tccataactt gattatcaac gagttcggtt gataccaaga
      301 gttcttcgta gagtttttca cctgggcgga ttccaacttc aacgattgga atttcacttt
      361 cagtgtggcc acttagaagc accatcttct tggccaagtc ataaatcttg actggtttgc
      421 ccatatcaag gataaagact tccccatctt tggcataagc accagcatgg ataaccagac
      481 ggctagcttc tggaatggtc ataaagtaac gggtcatgcg gaagtctgtc accgttacag
      541 gcccaccttc agcaatctga cgttcaaaga ctggaatgac actaccacgg ctaccaagaa
      601 cattcccaaa acgaactgca cagtaggttg attggctacg ttggttaaag ccagtgacaa
      661 tcaactccgc cacgcgcttg gttgctccca taacatttgg tggattgact gccttatctg
      721 tcgaaatcat aaccatctta ggcaccttgg cttcatcaac ggctctagca acattgtaag
      781 ttccacggat attgtttttg aaggcttctt ttggattgcg ctccatcata ggaacatgct
      841 tgtgggctgc cgcatgataa acaatagcag gtttgtactg ctcaaagact tgcaacaaac
      901 gatcatagtc ttgaatgtcc gcaatcacag gtacataatc aatcccttgg aacttacgaa
      961 tcaattcatg ataaacaagg tagattgagt tttccccatg accgagcaag acaatgcgtt
     1021 caggattgaa gcgactaact tgacgacaga tttcagaacc gattgaacct ccagctcctg
     1081 tgactaagat ggtcttacct gtcagttctg cacccagacg cgattcgtca agacggattt
     1141 cctgacgacc caaaaggtcc gtaatatcaa ttttttggaa gccagtacct gcttggtgaa
     1201 ggccctgaac aacagtttca accttaggca tcttgtaaca tttgacaccc agcttattac
     1261 acatctgcaa gatacgctca tattctgacg gatccagcga cggaatcgca acgatgacac
     1321 gctcgatttg atggcgtttg gctaattcag gcagattgtc ataagagccc aaaacaggaa
     1381 taccaccaag tttttgaccc tttttcttag aatccttatc caaaataccg accagttcta
     1441 attcactggt tggatgttgg taactatcca taaagagagc cccaccatca ccggcaccaa
     1501 tcaagaaggt ccgacggtgt tctccatcac cactaccttt tttgcgtctg gagtagatta
     1561 actgccaagt aatccgtggc aataaaatca agaaggtact caacaagata aagagaatga
     1621 taaaacggat ggagaagagt ggcaagaagg cataacagat actatatgac aagacactgc
     1681 tagcagtcac accaaaaaag attttcatga aatccgtaat cttgctgtaa cgactaatac
     1741 tcgcgctcaa gccccaaaaa tcaaccatca attgatagaa caggaaggcc aaactcgtat
     1801 agataatgta gtcaacaggt gctggattaa tcagcccata aaataaaata taagatacaa
     1861 tgatggaaac caccatactg aaaatatcaa atattcccca gaaaacctgc ttttgttgtt
     1921 tatttaaaat ttccaccaga tcaatcacat aatctgtgag ttttttattc atagaaattt
     1981 actcctcctt aaaatagttc tactatattg ttattatagc acattttaat ttatttggct
     2041 tatttttcca aataaattac tgttcccttg tactccttct tccatttaaa tcctctaatt
     2101 aaacctacaa tcgtcccaag gccataagca aagtgaatgg aaaataaaag aaagggcatc
     2161 acaattagaa atccattttt atgttttaat aaagtcagca aagtgagtaa tgacagtaat
     2221 gataaaagta gaaaataggc acctaatagt aaagttatga atacgaatgt gatcggtaac
     2281 aatgctagac taaacacaag actcaaaaca aataaacaag gaacataatg aaataatgat
     2341 aaacacttaa actgaacatg acttgtcaag ccaatccaca aaccatttga atacttttga
     2401 tgcagcattt tcttgaatgt tggtcgaata tactgataag atagaatact tgggctatag
     2461 cggattttat aaccatgttc tcgaattcta taatgaatat cattatcttc agttcggcca
     2521 agttgctcat ttactaaacc aaccttctgg aaaacctctc gtttatacat cccatgaaaa
     2581 atagaagaaa catatctatc ctcggaacta tttcgataat tggcaatgct actgccaaac
     2641 atattttcct caacaagatg caaggtctct gcccattttc cttttccttt gacaatcgtc
     2701 ggtctaggcc ctccacagac aaattcacct tgttgaataa cagccacatt gttcattaca
     2761 aaactctcag taacttttga atgagcatca atttttaaaa taaggccccc tacagaatgc
     2821 ttaactccca ggttaaaacc actagcttga tttttcttag gattgttata caatctaatt
     2881 gagttaaact ctgcatcttc ttttataaat tgctgaatga tagctgtggt cccatctgtg
     2941 gacatagcat ttataaatag aatttcaata ttctctttag gataggtttg attttttaag
     3001 tcttcaatta gaccaggcag atatttttct tcattgtatg cactgattac aatggatacg
     3061 agaagacttt caacattttg agtcactact actctcctga attttccctt ccaccattct
     3121 atcataattt tcaagacttt tccattttta tcttgaaagc cagaaacctt acttgacatt
     3181 atagtgaaaa agccttaaaa taagctgtta ttaaaatcag ctagaagaga tattatatga
     3241 aaaagcaatc actctttttt gttccaggta ttatcctgat tggtgtttcc ttgcgaactc
     3301 cttttactgt tttacccatt attttgggaa atatttcgca aggtctggag gtagaagtta
     3361 gttcgcttgg tgtcttgacc agcctgcctc tccttatgtt taccctcttt tcaccatttt
     3421 ctacccgact ggctcagaaa atcggcttgg agcatctctt cacctacagc ctcttcttct
     3481 tgaccatcgg ctcacttatt cgactaatca atctgcccct gctctatcta ggaaccttga
     3541 tggttggggc aagtgtcgca gtcatcaatg tcctgcttcc tagtcttatc caagccaatc
     3601 aaccaaagaa aattggtttt ctgaccacct tatatgtaac gtctatgggg attgcaacgg
     3661 ctctggcttc ctatctagct gtgcccatta cacaagccag ttcttggaaa ggacttatcc
     3721 tcctcctcac gttactctgt ctagcaactt ttttggtctg gctcccaaat caccgctata
     3781 atcatagact agctccacaa accaaacaaa aaagtcaaat aaaggtcatg cgtaataaac
     3841 aggtttgggc aattattatc ttttcaggtt ttcaatcctt gatcttttac accgccatga
     3901 cctggttacc taccatgtct atccatgcag gtctatccag tcacgaagct ggcttgctga
     3961 cttctatctt atctctgatt agcattcctt tttcaatgac catcccaagc ctgacaacca
     4021 gtttatctac tcgcaaccgt cagctcatgc tcactctggt ttcactagct ggtgtggtcg
     4081 gcatttccat gctctttttc ccaatcaata atttcattta ctggcttgcc atccatctcc
     4141 tcatcggaac cgcaaccagc gccctcttcc cttatctcat ggtcaacttt tcactcaaga
     4201 ccagcgcccc tgaaaagaca gcccaattgt ccggcctatc tcaaacagga ggctatatcc
     4261 tagcagcctt tgggccaacc ctctttggtt acagttttga cctattccac tcttgggtac
     4321 cagctgtagc tgccctcttg ctcatcgata tcctgatgac tgtggccctc tttacagtgg
     4381 acagagcgga taagatcctt taaacttcta gttttagcta gaagtttttt atatataaaa
     4441 attttacaca tttctcttga cagggctttc ttttagatgt acaatgtatg tgtagaaaaa
     4501 ttatatataa aaatcttaca cattagaaaa ggaggtttcc catgtacttt ccaacatcct
     4561 ctgccttgat tgaatttctc atcttggctg tactggagca gggtgattct tatggttatg
     4621 agattagcca aaccattaag ctgatcgcta atatcaaaga atccacactc tatcccattc
     4681 tcaaaaaatt ggaaggcaat agctttctga caacctattc tagagagttc caaggtcgca
     4741 tgcgcaaata ctactccttg acaaacggtg gtatagagca gctcttgacc ctaaaagatg
     4801 aatggacact ctatacagac accatcaatg gcatcataga agggagtatc cgccatgaca
     4861 agaactgaat acctgactca gctagaactc tatctcaaga aactacctga agctgaccgt
     4921 atcgaagcca tggactattt cagagagctc tttgacgatg ctggagtcga aggagaagaa
     4981 gaactcatcg ctagtttggg aactcccaaa gaagtggccc acgaagttct atccaatctt
     5041 ctcgataaaa aaatcaatga agcacccgct caaaaaaata accgacaaat tttacatatc
     5101 gccttgttag ccctccttgc agcacctatc ggcattcctc tgggaatcgc catcctcgtg
     5161 accctgttcg caatccttgt agccgctttg actgtcattc tggctttctt tgcagtttcc
     5221 atactgggta tcatcggcgg attcctattt ttagttgaaa gtttcactgt cctcgcccaa
     5281 gccaaatcag cctttatctt gatttttggt tctggtttac tggctatcgg tgcttcttcg
     5341 ctagttttac ttggcatttc ctatgtagct cgcttcttcg gtctactcat tgttcgtctg
     5401 gtacaatttg ttcttaaaaa aggaaagaga ggtaatcagc atgcgtaaat ggacaaaagg
     5461 atttctcatc tttggtgtgg tgactaccgt tatcggcttt atcctgcttt ttgtaggtat
     5521 ccaatctgac gggattaaga gcctactttc catgtccaaa gaacctgtct atgatagccg
     5581 tacggaaaag ctaacctttg gcaaggaagt cgaaaaccta gaaattactc tccaccaaca
     5641 cacgctcacc atcacagact ctttcgatga tcaaatccac atttcttacc atccatctct
     5701 ttctgctcac catgatctta tcaccaatca gaacgataga actctgagtc tcactgataa
     5761 gaaactgtct gaaactccgt ttctctcttc tggaattggt gggattcttc atatcgcaag
     5821 tagctactct agtcgttttg aagaagttat tctccgacta ccaaaaggga gaactctaaa
     5881 agggatcaac atctcagcca atcgcggaca aaccaccatc ataaatgcta gccttgaaaa
     5941 tgcgaccctc aatacaaaca gctatatcct ccgaattgaa ggaagtcgta tcaaaaacag
     6001 taaactcaca acgcccaata tcgttaatat ctttgataca gttcttacag atagtcagct
     6061 agagtcaaca gagaatcact tccacgctga aaatatccaa gtccatggta aggttgaact
     6121 gactgccaaa gattatctca gaatcatcct agaccagaaa gaaagccaac gaattaactg
     6181 ggacatctca agcaactatg gttctatctt ccaattcaca agagaaaagc ctgaatcaag
     6241 aggtacggaa ttaagcaacc cttacaaaac tgaaaaaacc gatgtcaagg atcaactcat
     6301 tgcgagatct gatgataata ttgatctaat atccacacca agcagacgtt gacaaaaacg
     6361 cttacatctg ctactatgga agcatattta tctaactaaa aaggaggttc taccatgaaa
     6421 caagaatggt ttgaaagtaa tgattttgta aaaacaacaa gcaagaacaa gcctgaagag
     6481 caagctcaag aggttgcaga caaggctgaa gaaacgatag ccgatctcga tacaccaatt
     6541 ggaaaaaata ctcaagtaga ggaggaagtc tctcaagctg aagtcgaact ggaaagccag
     6601 caagaagaga aaattgaaac tcctgaaggc ggtgaagcga gaacagaaat agaagaaaag
     6661 aaggcatcta attctactga agaagagcca gacctttcta aagaaacaga aaaagtcact
     6721 atagctgaag agagccaaga agctcttcct cagcaaaaag caaccacgaa agagccactt
     6781 cttatcagta aatctttaga aagtccttat atccccgacc aagctccaaa atctagggat
     6841 aaatggaaag agcaagtgct tgatttttgg tcttggctag tggaagcgat caaatctcct
     6901 acaagtaagt tggaaacaag tatcacacac agttacacag cctttctctt gctcattctg
     6961 ttttctgcat cttccttttt ctttagtatc tatcacatca aacatgctta ctatggacat
     7021 atagcaagca ttaacagtcg cttccctgag cagctagctc ctttaactct tttttctatc
     7081 atctctatcc tagtagcgac aacactcttc ttcttttcat tcctcttggg tagtttcgtt
     7141 gtgagacgat ttatccacca ggaaaaggac tggacgctag acaaggttct ccaacaatat
     7201 agtcaactct tggcaattcc aatcttcctc actgctattg ctagtttctt tgctttcttt
     7261 gatagcctac gatttacggc cctcttgtgt gtgattagca ttggaatcat tctgcttgcc
     7321 agtctccata tcattacaag accaagtcaa gcaagtgaaa ccgactcctt ctatcaatta
     7381 ttcttgtctg tccttgtgaa cggagttatt atcctcctct tctttgtagc tgaagtggca
     7441 ctgattggag attatcttcg tatcttggcc tttctttaaa attcaatcct gtcatccttg
     7501 gcaggatttt ttctatgtca aaaaagcaag tcgattgacc tgcttctgct ttacttttct
     7561 tgtgctaatg ttttaaaatc tttgtctaat atgggttgca cttctatttg attggcgtct
     7621 agttggtggt aaaaagatgg gggtaatacc tctaagaatt ttgcatagtc caagcgagca
     7681 atggcttcat agtcttctgg tttagagcca tctcctgtga tttgaaccaa gtcaatctcc
     7741 cactgcactt ccttatccac caattgctca atataggctg caggaacaaa cggttctctc
     7801 ggtaaaactg tcttgactcc ttgagctaga tggtaaacgc catgcacttt tccttctcca
     7861 tcctgataga aggaaactct cgcaaagtag gcatctgtct cttgaaccgc acgcacacgc
     7921 gcttcaaact gagccaaacc atctgcctct aaaaagcttt tcaagttctc acgactaaag
     7981 aaaataggat taaaaattcc ttggcaaatc gtaaaacgag ctacagggtc tgctagatag
     8041 gcttgaatac ttgcttggaa ataagcttca aaatcaaaac catctagccc ttcaatatca
     8101 gtccctgtat aagcaagcaa agcatctaaa aatgacttga taatctgcca gtctgtctct
     8161 gttagtaggt caggaagatc gacacggtaa gccttttgac catcagcata actgacctta
     8221 aaaagaaatt gtgattgccc cactatcgca cactcaatat actcgagacg attaagaggc
     8281 tgacggagat agactacatc atagatatgt gactccaaac cgtctagcaa tgccaagatc
     8341 gacttggcat tcaaaatctc ttgttctcct aaaatgctct gtttatttgg aataaaaaat
     8401 gttttcgcca taactggact cctttgaaat cgcttacata cagtatacct tatttttctg
     8461 aaagatacag aaacaaactt tagatttttg agtacaaagc atagaaaaac agcccctgag
     8521 gactgtttga tcttatacag tagctgcttg atccaagctt tcaccgatag cggctaggcg
     8581 ctcgatcact tcagcttgtg tcaattcatt ttttgaaaca tagcggttac gtgggtgaac
     8641 acggcactcg tgtgagcatc cacgaaggta cttgtcttca ttttcttctg atgtcaagat
     8701 acgacggtta cagaagggat ttccacagtt gacataacgt tcacatggtg ttccatcaaa
     8761 ccagtctttc cctacgatgg ttgggttgac atggttgaca tcaacggcga tacgctcgtc
     8821 aaatacgtac atttttccat cccaaagctc accttgaact tctgggtctt taccgtaagt
     8881 tgcgattcct ccgtgcaatt ggccgacatc tttgtagcct tcacggacca tccagcctga
     8941 gaatttctca cagcgaacgc cacctgtaca gtaaaccacg acacgcttgt ccatgaattt
     9001 ttccttgtta tcacggaccc attgtggtaa ctcacggaag ttgcgaatat ctgggcgaat
     9061 agctccacgg aaatgtccta ggtcgtactc ataatcgtta cgtgtgtcaa ggacaacggt
     9121 atctttatca agaagcgctt ctttgaactc ttttggagac aagtaagcac ctgttgtttc
     9181 aagtgggttg atgtcattgt caaagtcgtt gtcttccaaa ccaaggtgga caatttcttt
     9241 cttgtagcga acaaacatct tcttgaaggc ttgttcattt tcttcgtcaa tcttgaacca
     9301 gagttcttcc attcctggaa ggctgtgaac gtagtccatg tatttttgag ttgtttcata
     9361 gtcacctgaa actgttccgt taattccctc gtcagcgact aggatacggc ctttaagacc
     9421 gattgattta cagaaagcca agtggtctgc agcaaattgc tctgcatttt caattggagt
     9481 ataaaggtag taaagtaaga cacgaatatc ttttgccata agatttgttc tcttttctat
     9541 tcttaaattt tctaaatttt ttatttatcc atactagtat acctgcttga gaaaacgaat
     9601 gcaatttatt tgactggaaa ttgtagagga ttctcgaaat ttcctgaatg gttaaaataa
     9661 ggacaagaga aaacatggat atctatatcc ttgtgccaaa aaaaccactg ccctccccag
     9721 accaacctga ggaaagcagt gattcttatt ttaggagtta ggaatgaata cacgaaatca
     9781 atttagctga ttattttttg tttttcaaga attcatcgta ttgtttttgc atttcgttca
     9841 atactttttc gtaggcacct tcagatttca atttttccat caattctgga atcgctttat
     9901 ctgggtctac agtaccagtg ttgatagctg tatcaaattg ttgcattgtg ttagcaatag
     9961 ctgagatttc agatttcaca ttgtcagtat tgaagataaa tccaagcgct ggagattctt
    10021 tagcttctgc caattctttc ttagaatttt cgatttgttg gtctgtaacg ttttcgttga
    10081 tgtaaaggat ccagttgtta ccagtgttcc atccacccat gtgagtgttt cctttgtagc
    10141 catcaagaac gcgaacacgg ttttctttac cttcaatttt ttcccagttc ttgccttctg
    10201 gaccgtaaac aagaccgttc aaaagttctg ggttcgtatt caagaggttc aagatttcca
    10261 ttgatttttc tttgttctta gagttgtttg agatgacaaa gttagcaact tgtgttgttt
    10321 ggtttttctt gatgaagtta gtgattggtt tgatttggat atctttgttg gcaacacgtg
    10381 aaagcaagct gttaccgtag tcagctggtc ctactgtttc ttcacgaacg aaccaagtat
    10441 cttgttgaag gtcaaatgaa gtatcgcttg ttgcgacgtc ttttggaatg tagccagctt
    10501 catagaattt gtgaagagtc ttcaagtgtt ctttgaaacg aggcacttcg taacggttta
    10561 caactttagt agtatcgcct tcaaggtcaa taacgaatgg aagcccgttt gctactgggt
    10621 agtcaaaatt atcagatggg atgaaaactt taccaatagc aaatggtact acgtctggag
    10681 ctttttcttt gatttgtttc aagactggct caagagtttc gtaagaagta acacctgaaa
    10741 tatcgatacc atatttggca aggagagttc cgttgaaggc aaagttttga gatgatgcta
    10801 cgttggctgc aactggtaca gcataaatct taccatttac agtattaccc ttgatataag
    10861 ctggatcaag tgccttgtaa aggtctttac cttctttttt gtacaattct gtcaagtcag
    10921 cataagcacc tttttgagca tttacaatat agttatctgc aaaggcgata tcatagtttt
    10981 caccagatga tgtgataact gacattttct taccatagtc accccagcca aggtattgga
    11041 tatccaattt ggcaccaact ttttcttcga tgattttgtt ggcatttgct aacaattcat
    11101 ccaagttatc tggtttgtca ccgatttggt acattttgat aacaggtttg tcacctgaat
    11161 cagcagcttt tttgctgtta cctgtcaaat ttccacaagc agcaagacct gcagccagag
    11221 cgactacact agcagatgca aaagcatatt ttttccagtt tttcatgata aaaactcctt
    11281 tttttatttt taaacttata aacaatgtaa tgatcttaac ttcacacaag ggaagttggg
    11341 aactgagaaa tgttcttttt caataagcac tattctttca caccaccgat agtcaaacct
    11401 tttacaaagt agcgttggaa gaatggatac aaaatcgcga ttggaagggt tgctaccaca
    11461 accatggcca tacgacctgt ttctttcggt agagcaactc ccagttgacc agtcaagccg
    11521 accgctttgg caatgtagtc catattttgt tggatttgca tgagcaaata ttgcaatgga
    11581 tacaagttat cactcttgat gtaaagaagg gcgttgaacc agtcattcca gaaaccaaga
    11641 gctgtcaaaa gcgtgatggt tgcgatacct ggtagtgaca atggcaaaca gatttggaag
    11701 aaaatccgag cctcactggc accatcgata cgagccgatt cgagaatggc ttctggaatg
    11761 gtcttcttga aaaaagaacg catcaagatg atattgaatg gtgagagaag cattggaaca
    11821 atcaaggccc aaacagtgtc accaagctga agtacacggg tcaccatgat ataacctggt
    11881 accaaaccag cgttgaacaa catactgaga aggacgaaga tggtaaaaaa tctgcgatac
    11941 ttaaaggttg tccgtgaaat agcgtaggca taggttgttg tgataaagac atttgtcaat
    12001 gtcccaacta cggttacaaa gacagagatg aagagggctt gtaggatttt atccttaaac
    12061 tgtgccaaaa actcaaaacc gtctaagcca aattgggatg ggaagaagct atagccgtat
    12121 tggaggaggc ttttctcgtc tgtcactgaa ataatgataa cgaatacaaa aggtaggata
    12181 caagagaggg caatcaaacc cgaaatgata ctgaagaaga tatctgcttt cttactgaag
    12241 gagtgaatgc cgacattatc aattttttct tttttaattt tcttttttgc catattctcc
    12301 tcctttctag aacaaagctg agtttggatc gactcgtctt gcaagcaagt ttgataggat
    12361 aaccagaatc aaaccaacaa cggattggta aagaccggct gctgcagcca taccgatatc
    12421 tgctgtctga gtcaaaccat taaagacata tacgtccaaa acgttggtta cattgtaaag
    12481 ctgaccagca ttgtgtggga tttgatagaa gagaccgaag tctgcgcgga agatatttcc
    12541 gactgcaagg atggtcaata cagttacaag cggagtcaac tgaggaatgg ttacgttgcg
    12601 aatacgttgc cacttgctag ctccgtccac tgtcgctgct tcgtagtagg ttggatcaat
    12661 tcccatgatc gtcgcatagt acatgacact gctatatcca aagcctttcc aaatacctag
    12721 gaaaagtagg agatagggcc agatgcccag gtcagcgtag aaattgactt ctttgagacc
    12781 aagactttcc aatagatgat tgaacacccc tttatcaata tttaggaagg catctgtaaa
    12841 gaaactgatg ataacccaag acaagaagta agggaacaac atagaagttt gaaaaatctt
    12901 caccattctc ttagaacgga gctcgctgag gataatggca atccctacag atacaactaa
    12961 acctagaaag ataaagccaa gattgtagag gacagtattt cgtgtgataa taaaggcgtc
    13021 tcttgaacta aataagaatc tgaaattatc gagtccgacc catttactat ttatgatact
    13081 atctatgaaa ccattactgg tcatgtggta gtctttgaag gcaaccacgt tcccaaatac
    13141 tggaatgtaa aagaatagaa tcaaccagag tgcccctggc aaaaccatca agagaaagat
    13201 ccagttgtct ctcaatgttt ttgaaaactt tttcataatt tcctcccttt ttattttgat
    13261 atccatctaa aaattctttt ttagactttt gataacgatt acattattag tatactccta
    13321 tttgcaggtt aggttaaact cctaattata gaaaaaactc cacaaattat gtagcagatt
    13381 taaaacttta tcaccactat caaacaaatg tcctaaatca attgtttatt ttatctctat
    13441 tagcccagtg atggcgtcac tctgttataa gcatccaaca acggggtata ctgaaaaatc
    13501 tccagactag ggaactcagc gatagttcct aatctggaga tttttaatat gttattaggc
    13561 gtttgctttc aacttagcaa taacctcttt aagattatca atcaactctg cttcagtatg
    13621 ctcagagcct ttttcatctg ccaagaacaa aactgctttt tgaagttctt cttgagagtt
    13681 ttcaaggaca tccttatctg ctgtttcttt gcccgctgtt tgtcctccat ccttagttgc
    13741 tgactggctt tccttaatgg actctaggga agcaatggca tctttgactg tttgcaagat
    13801 atcacgtaaa ccttgctctg tcaaactatc atctgcaaaa gctttcttag cctctgccaa
    13861 aaccagacgt gctgaatctg tggtaggatt cgatacacct gtcaatgatc tcaaaagatt
    13921 ttctaaagtt tgagtctgct tactaatact agactaaaat caaaaagcat tatataacag
    13981 tgatatgaaa tcaactaaag aagaaatcca aac
//
LOCUS       DAVBDR010000055        13451 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.055, whole genome shotgun sequence.
ACCESSION   DAVBDR010000055 DAVBDR010000000
VERSION     DAVBDR010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13451)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13451)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13451
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.055"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            complement(<1..1307)
                     /locus_tag="VQ540_001691"
     CDS             complement(<1..1307)
                     /locus_tag="VQ540_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec-dependent serine-rich glycoprotein
                     adhesin"
                     /protein_id="HET2545460.1"
                     /translation="MFKVMRGGVDTTQVMTETVEDKVSHSITGLDILKGIVAAGTVIS
                     GTVATQTKVFTNESAVLEKTVEKTDALATNDTVVLGTISTSNSASSTSLSASESASTS
                     ASESASTSASTSASTSASESASTSASTSISASSTVVGSQTAAATEATAKKVEEDRKKP
                     ASDYAASVTNVNLQSYAKRRKRSVDSIEQLLASIKAAVFSGNTIVNGAPAINASLNIA
                     KSETKVYTGTGLDSVYHVPIYYKLTVTNDGSKLTFTYTVTYVDPTTRALGNLSKMGHG
                     YSIYNTGTSIQTMLTLGSDLGTPSDVKNYITDKDGVLVRSYNTSTMTTWGSGYTWGNG
                     AQMNGFFAKQGYGLTSSWTVPITGTDTSFTFTPYAAKTDNIRTNYFKGRGKVVESSTT
                     SQSLSQSKSLSVSASQSASASASTSASESASTSASASASTSAS"
     gene            complement(1305..1418)
                     /locus_tag="VQ540_001692"
                     /pseudo
     CDS             complement(1305..1418)
                     /locus_tag="VQ540_001692"
                     /inference="COORDINATES: protein motif:HMM:TIGR03715.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="KxYKxGKxW signal peptide domain-containing
                     protein"
     gene            complement(1656..2117)
                     /locus_tag="VQ540_001693"
     CDS             complement(1656..2117)
                     /locus_tag="VQ540_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000514209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2545461.1"
                     /translation="MGKERRKQGNLERKKRVVKKRKIPLEELKAFVEAHPDAFLREIA
                     ARFDCALPSVWAVLKQIKVILKKTTSFREQKPEKVSEFLDILDNLKDLPVLYIDETGI
                     NRYLYRPYAGAPRGEKVYDKISGRRFERTNEVEQKLNGSFLIRYIDSQIRE"
     gene            complement(2084..2227)
                     /locus_tag="VQ540_001694"
     CDS             complement(2084..2227)
                     /locus_tag="VQ540_001694"
                     /inference="COORDINATES: protein motif:HMM:NF013842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET2545462.1"
                     /translation="MAYSTDFKQGALDSIKEGHSHVEAAKFFGVGVRTLFTWEKKDVN
                     KGT"
     gene            2496..2876
                     /locus_tag="VQ540_001695"
     CDS             2496..2876
                     /locus_tag="VQ540_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HET2545463.1"
                     /translation="MTYLEKWFDFNRRQKEIESLLEETIAQQSEQSLTLKEFYLLYYL
                     DLAEEKSLRQIDLPDKLHLSPSAVSRMVARLEAKNCGLLSRMCCHQDRRSSFICLTND
                     GQKTLASLQKTVEESLEAGLDFLI"
     gene            2975..3196
                     /locus_tag="VQ540_001696"
     CDS             2975..3196
                     /locus_tag="VQ540_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HET2545464.1"
                     /translation="MIEITYIDASKNERTVTFESYEDFERSQQACLIGVADYYPVQKL
                     TYKGHNLDYHGTYGDIFFYLMKQDLSQYN"
     gene            3213..3527
                     /gene="trxA"
                     /locus_tag="VQ540_001697"
     CDS             3213..3527
                     /gene="trxA"
                     /locus_tag="VQ540_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003004519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HET2545465.1"
                     /translation="MAKAITDATFEQETKDGLVLVDFWATWCGPCRMQGPILDKLSEE
                     LSEDVLKIVKMDVDENPNTARAFGIMSIPTLLFKKDGQVVKQVAGVHTAEQIKAIIAE
                     LS"
     gene            3834..4367
                     /gene="queF"
                     /locus_tag="VQ540_001698"
     CDS             3834..4367
                     /gene="queF"
                     /locus_tag="VQ540_001698"
                     /EC_number="1.7.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent 7-cyano-7-deazaguanine reductase
                     QueF"
                     /protein_id="HET2545466.1"
                     /translation="MKHQSALVVFSGGQDSTTCLFWTMQHYETVEAVTFAYGQHHHLE
                     IQITREIAKEQGIRHHILDMSLLGQITAQPDFATIHISYIPDKLCVESKSLKLYLFSY
                     RNHGDFHENCINTIGKDLVNLLDPRYLEVWGKFTPRGGISIDPYYNYGKQGTKYEGLA
                     EQRLFQHDLYPEKIDNR"
     gene            complement(4621..5289)
                     /locus_tag="VQ540_001699"
     CDS             complement(4621..5289)
                     /locus_tag="VQ540_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin"
                     /protein_id="HET2545467.1"
                     /translation="MKKFVAELIGTFMLVFVGTGAVVFGNGLDGLGHLGIAFAFGLAI
                     VVAAYSIGTVSGAHLNPAVSIAMFVNKRLSSSELVNYILGQVVGAFIASGAVFFLLSN
                     SGMSTASLGENALANGVTVFGGFLFEVIATFLFVLVIMTVTSESKGNGAIAGLVIGLS
                     LMAMILVGLKITGLSVNPARSLAPAVLVGGAALQQVWIFILAPIAGGVLAALVAKNFL
                     GTEE"
     gene            complement(5400..5954)
                     /locus_tag="VQ540_001700"
     CDS             complement(5400..5954)
                     /locus_tag="VQ540_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2785 domain-containing protein"
                     /protein_id="HET2545468.1"
                     /translation="MYQDLLRKIAEEKPNYNQEEIQWLFDHLGNPSPEIRNVLLNQGL
                     HYLSKEKDTRGFSSQYGWVHAFAHGADLLTEVVCHPGFPKNRVHEVFEILGQLFKRMS
                     IRFTDDEDWRLARVIYEPILQGKLAQEQVASWIKTVDFPIEEREDFYKFSNFRSCLVE
                     VYVQLDQRNSLQDELKEAIQSFQY"
     gene            complement(6200..7996)
                     /gene="pepF"
                     /locus_tag="VQ540_001701"
     CDS             complement(6200..7996)
                     /gene="pepF"
                     /locus_tag="VQ540_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HET2545469.1"
                     /translation="MEQKHRSEFPEKELWDLTALYQDREDFLRAIEKAREDINQFSRD
                     YKGNLHTFEDFEKAFAELEQIYIQMSHIGNYGFMPQTTDYSNDEFANIAQAGMEFETD
                     ASVALTFFDDALVAADEEVLDRLGKLPHLTAAIRQAKIKKAHYLGADVEKALTNLGEV
                     FYSPQDIYTKMRAGDFEMADFEAHGKTYKNSFVTYENFYQNHEDAEVREKSFRSFSEG
                     LRKHQNTAAAAYLAQVKSEKLLADMKGYDSVFDYLLAEQEVDRVMFDRQIDLIMKDFA
                     PVAQRYLKHVAKVNGLEKMTFADWKLDLDSALNPEVTIDDAYDLVMKSVEPLGQEYCQ
                     EVARYQEERWVDFAANSGKDSGGYAADPYRVHPYVLMSWTGRLSDVYTLIHEIGHSGQ
                     FIFSDNHQSYFNAHMSTYYVEAPSTFNELLLSDYLENQSNDPRQKRFALAHRLTDTYF
                     HNFITHLLEAAFQRKVYTLIEEGETFGASKLNSIMKEVLTDFWGDAIEIDDDATLTWM
                     RQAHYYMGLYSYTYSAGLVISTAGYLHLKHSETGAEDWLNLLKSGGSKTPLESAMIIG
                     ADISTDKPLRDTIQFLSDTVDQIISYSAELGE"
     gene            complement(8007..8750)
                     /locus_tag="VQ540_001702"
     CDS             complement(8007..8750)
                     /locus_tag="VQ540_001702"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001188214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HET2545470.1"
                     /translation="MQQYFVKGSAVSPVTIEDRETSKHMFQVMRLKEEDEVTLVFDDG
                     IKRLARVLDMENRQFELVQELNDNVELPVQVTIASGFPKGDKLEFITQKVTELGASQI
                     WAFPADWSVAKWDGKKLGKKVEKLEKIALGAAEQSKRNVVPSIHLFENKADFLAQLDQ
                     FDRILVAYEEAAKEGEAAALIKAVTGLEKGAKLLFIFGPEGGLSPAEIENFEAKGAVL
                     AGLGPRILRAETAPLYALSALSVLVELEK"
     gene            complement(8752..9702)
                     /locus_tag="VQ540_001703"
     CDS             complement(8752..9702)
                     /locus_tag="VQ540_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000451122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HET2545471.1"
                     /translation="METWQELKVTVKREGEELVSNLLIELGAQGVAIEDSMDYMGNVD
                     RFGEIFPEVEQQEEIVVTAYYPDTVDMTVVEADLQARLAELTDFMDLGELKIGTTALA
                     EEDWADNWKKYYEPARITHDLTIVPSWTDYEATAGEKIIKLDPGMAFGTGTHPTTKMS
                     LFALEQVLRGGETVLDVGTGSGVLSIASSLLGAKEIFAYDLDDVAVRVAQENIELNTG
                     MENIHVAAGDLLKGVEIEADVIVANILADILIHLTEDAYRLVKDEGYLIMSGIIKDKW
                     DMVRQSAESAGFFLETHMIQGEWNACVFKKTKDISGVIGG"
     gene            complement(9840..10268)
                     /locus_tag="VQ540_001704"
     CDS             complement(9840..10268)
                     /locus_tag="VQ540_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HET2545472.1"
                     /translation="MELEISDFQGCKIALFCGDKLLTILRDDKDDIPCPNMWELPGGG
                     REGDESPFECARREVYEELGIHLDEDCLLWSKIYPSVIFKGKKSVFMVGQLRQEQFDN
                     IIFGDEGQGYQLMNVEEFLSSSQVVPQLQERLKDYLKVSD"
     gene            complement(10249..11337)
                     /locus_tag="VQ540_001705"
     CDS             complement(10249..11337)
                     /locus_tag="VQ540_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000719715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-2 protease family protein"
                     /protein_id="HET2545473.1"
                     /translation="MKKIGTYLVYVLAVVFIMLAFACGTIAFAELGYSAVLAFTFGYA
                     FALLSMYLIFILHELGHAFCGYLTGYRLVAFGLGHFILTKKSGRFHLSRTAILKNVGA
                     QYIGLKEDESDQRIILMLSGGLMVHLGLILLAIVFGFLTRSWYFAGTWIFLNLSFFLN
                     NILPVDITDGAKIWELLQHPENTKYAYLVLRHSAQTLLAPQEYDLKDFVQAVPEDARG
                     SFADGVLGMQGEVSILEGKEEVAKQQFQALLERTTTPMMQTVAQLSLLHIALLEGDFE
                     QAEQYASIRQVKSFLSLKLSNLQVIQAWYQLKVKKDVDRTRKALKIARQKMDSSRMLR
                     DEKRYYENLLAELEKEMLEGTEDGTRNF"
     gene            complement(11356..11826)
                     /locus_tag="VQ540_001706"
     CDS             complement(11356..11826)
                     /locus_tag="VQ540_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HET2545474.1"
                     /translation="MATYGFLDVLEEELDKNFPFDFEISWDKRNHAVEVSFLLEAQNA
                     AGVEMVDEDGEVSSDDILFEEAVLFYNPAKSTVNEEDYLTVIPYLPKKGFSREFLAYF
                     VLFLKDTAEVGLDVLMDFLEDPEAEEFVMEWNQEVFEEGKVGLEEGEFYPYPRY"
     gene            complement(12117..12569)
                     /locus_tag="VQ540_001707"
     CDS             complement(12117..12569)
                     /locus_tag="VQ540_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000961815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HET2545475.1"
                     /translation="MLVTYPALFYYDDTDGTEATYFVHFPDFEYSATQGEGISEALAM
                     GSEWLGITVADLIESDGELPQPSDINSLSLIDNDPFKDDEDFVSTYDLDKSFISMVSV
                     DVSEYLGSQEPIKKTLTIPKWADKLGREMGLNFSQTLTDAIADKKVQA"
     gene            complement(12606..12785)
                     /locus_tag="VQ540_001708"
     CDS             complement(12606..12785)
                     /locus_tag="VQ540_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HET2545476.1"
                     /translation="MPMTQKEMVKLFTAHGWIKTRGGKGSHIKIEKQGERPITILHGE
                     LNKYTERGIGKQAGL"
     gene            complement(12922..13101)
                     /locus_tag="VQ540_001709"
     CDS             complement(12922..13101)
                     /locus_tag="VQ540_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2545477.1"
                     /translation="MNLIFEEYQFVKIGDKKYRVRSGPMIHSTPPQSVLDRDTFTIDY
                     TDDELLDKEAVFTTH"
     gene            complement(13266..>13451)
                     /locus_tag="VQ540_001710"
     CDS             complement(13266..>13451)
                     /locus_tag="VQ540_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000818079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2545478.1"
                     /translation="IFTKQIRHWILSDQVISGKRKLFFREDTPKEILDLYENIKSKLD
                     FAYQEVHSNNGLKKYEK"
BASE COUNT         4008 a         3061 c         2435 g         3947 t
ORIGIN      
        1 tctgatgcac ttgtacttgc tgaggctgat gcgctggttg aggccgattc agaagctgag
       61 gtgcttgctg aggctgaggc gctttgacta gcacttactg agagtgactt agactgtgaa
      121 agtgactgac tggtcgtgct agattcaact acctttcctc tacccttgaa gtagttagtt
      181 ctaatgttat ctgttttagc agcgtaaggg gtaaatgtaa aggatgtatc cgttccagta
      241 attggtacag tccaagatga tgttaatcca tatccttgct tagcaaagaa accattcatt
      301 tgggcaccat ttccccaagt atacccacta ccccacgtcg tcattgtaga tgtattatag
      361 gatcgaacca gtacaccatc tttgtcagta atgtagttct ttacatctga aggggtacca
      421 agatcactgc caagggttaa cattgtttgt attgaagtac ctgtattata gatagaatac
      481 ccatgaccca tctttgaaag attaccaaga gcccttgtgg taggatctac atacgtaacc
      541 gtataggtaa aggtcagttt tgaaccatca tttgtcactg tcaatttata gtaaattgga
      601 acatgatata ccgaatctaa acctgtacct gtataaactt ttgtctcact tttagcaatg
      661 tttagacttg cattaattgc aggggcgcca tttacaatcg tattgccaga aaaaacagca
      721 gcttttatag aagccagcaa ttgctcgatg gaatccactg aacgcttgcg tcgcttagca
      781 taagattgga gattgacatt tgtaactgat gctgcataat cactagctgg tttcttacga
      841 tcttcttcga ccttcttagc agttgcttct gtagcggcag ctgtttgtga tcctaccaca
      901 gtagatgatg cagagatact tgtcgaagcc gatgtacttg ctgattctga tgcacttgta
      961 ctcgctgagg tcgaagcgct ggttgaggct gactcagatg cagatgtact tgccgactct
     1021 gaagctgaca aactagttga actcgctgaa ttacttgtag atatcgtacc tagaactact
     1081 gtatcatttg ttgccaaagc atccgttttc tctacagttt tttcaagtac tgccgactca
     1141 tttgtaaata ccttcgtttg agttgcaacg gttccactta tgacagttcc cgcagcaact
     1201 attcccttga ggatatcaag cccagtaatt gaatgactta ctttatcttc taccgtttcg
     1261 gtcatgacct gagtagtatc aacaccacca cgcatgacct taaacaagcc aaaaagagaa
     1321 gtcgaggccc gtagccaatg cttccctgat ttgattaatt tgaaccgagt tactcggtct
     1381 gtttctctat attcaccctt ctgacgtcta aaaaatattt tgaaatttcc tttcgagtat
     1441 tattttcatg tatggatata aataaattac catactataa ttatagaata gggaacccaa
     1501 aatagcaaga aacttgaggt atttttgcta aaaaaaaaaa gcattttact attttatata
     1561 tatattataa gataagtttt ttataaagac acgcaaatga gtataaatca gctaattttt
     1621 ggtttatatt cctattttta tgcataatta ttctttcatt ctctaatttg tgaatcaata
     1681 tatctgatta gaaaactacc attgagtttt tgctccacct cattagtccg ctcaaaacgc
     1741 cgtccgctaa tcttgtcata gactttctcc cctctaggag cccctgcata aggacgatag
     1801 aggtagcggt tgattcccgt ttcgtcaata tataggactg gtaaatcttt taggttatcc
     1861 aaaatatcaa gaaactcaga aactttctca ggcttttgtt ccctaaaact ggtcgtcttt
     1921 tttaaaatga ccttaatctg ctttaaaact gcccatacgg agggcaaagc acaatcaaaa
     1981 cgggccgcaa tttcccgtaa aaaagcgtct ggatgagcct ctacaaaggc tttcaattct
     2041 tctaaaggga tcttacgctt tttgacgact cgctttttcc gctctaagtt cccttgttta
     2101 cgtctttctt ttcccacgtg aagagagttc tgacgccaac accaaaaaac ttggctgcct
     2161 cgacatgact gtgcccctct ttgatggaat ctaatgctcc ttgtttaaaa tcagtactat
     2221 atgccatagc tttattagac catgcttatt ttaaactaag caactataga tagagaaatg
     2281 aaataaaatc taaattcgaa tgtgataagg agttagaaat tgaaacaata ggattccccc
     2341 attattcaca caaaaataaa accactaaaa aacagagctt gccagcattc ttgaaaagta
     2401 gtataattat tgcatgcgca atcatcttgt gacgcagaga ctgcccgtta atggactttc
     2461 ttctatatta tgactctaaa aagaaaggag acactatgac ctatttggaa aaatggtttg
     2521 acttcaatcg gcgtcagaaa gaaattgaaa gtctcttgga agagaccatt gcccaacaga
     2581 gcgagcaaag tctgaccttg aaagagttct acctgctcta ctatctggac ttggctgaag
     2641 aaaaatctct acgccagatt gacctgccag ataaacttca tctgagcccg agcgcagttt
     2701 ctaggatggt ggctcgcttg gaagctaaaa attgcggtct actcagtcgc atgtgttgcc
     2761 atcaagatag acgctctagt tttatctgcc tgacaaatga tgggcaaaag acactggcct
     2821 cgctacaaaa gactgtcgaa gaaagcttgg aagcaggttt ggatttcttg atttaagatg
     2881 attttaaaaa aagttgcgtg cgcaatcatt tttcttgaca ttctctttta taaggagtaa
     2941 aataaagtta gcattaaaca aaggagtttt aaatatgatt gaaattacct atatagatgc
     3001 cagcaagaac gaaagaactg tgactttcga gtcttatgaa gactttgaac gttcacaaca
     3061 agcttgcctt atcggcgtcg cagactacta ccctgtccaa aaattaactt acaagggtca
     3121 taatttggac taccatggga cttatggaga tatcttcttc tatctcatga aacaagattt
     3181 aagccaatat aactaaaaaa aggagaaata caatggcaaa agcaattaca gatgcaacat
     3241 tcgaacaaga aacaaaagac ggtttggtct tagtagactt ctgggcaact tggtgtggtc
     3301 catgtcgtat gcaaggtcca atcttggaca aattgtctga agaactttca gaagatgtct
     3361 tgaaaatcgt taaaatggac gttgatgaaa atccaaacac agctcgtgct tttggaatca
     3421 tgtctattcc aactcttctc ttcaaaaaag acggccaagt tgtcaaacaa gttgcaggtg
     3481 ttcacacagc agaacaaatc aaggccatca ttgctgaatt gagctaatca aacgagagac
     3541 caagtacttt ctttggtctc ttttttcttg ccctttgcca tttttcaaaa aatatgctag
     3601 actatagtag attgaaacta gaatagtaca cctctacttc taaaacattg ttaaaaatcg
     3661 atttgactgt cctgatcgat ttgtcctgtt tttatttcat tttactatat aagtagaata
     3721 ttacgatgtt tgggatatgc catcgctaaa aaaaaactcg atttggtatt ttttagttcc
     3781 ctaatgggag ctttttgcgt gctctgaaca tttcccattt tggaaggagt actatgaaac
     3841 atcaatcagc cttggtcgtc tttagtggcg gtcaagattc aacaacctgc cttttctgga
     3901 ccatgcaaca ctatgaaaca gtcgaagctg tcacctttgc ctacggccaa catcatcacc
     3961 tcgaaattca aattactaga gaaatcgcta aggaacaggg cattcgtcac catatcctcg
     4021 atatgtctct gctgggacaa atcactgctc agccagactt tgcgacgatt catatttcct
     4081 acattcctga caagctctgt gtcgagtcaa aatccctcaa actatatcta tttagctacc
     4141 gaaaccacgg agatttccac gaaaactgta tcaacaccat cgggaaagac ttggtcaact
     4201 tgctagaccc tcgctattta gaagtctggg gaaaattcac tccgcgcggt ggcatttcaa
     4261 tcgaccccta ctataactac ggtaagcaag gaactaagta tgagggcttg gcagaacaac
     4321 gcctcttcca acacgacctt tatccagaga aaattgacaa ccgctaaagt catactcaat
     4381 gaaaatcaaa gagcaaacta ggaagttagc cgcaggttac tcaaagcagt gtttgaggtt
     4441 gtagataaaa ctgacgaagt cagatcaaaa cactgttttg aggttgtgga tagaactgac
     4501 gtagtcagta accataccta cggcaaggta aagctgacgt ggtttgaaga gattttcgaa
     4561 gagtatcata cgaaaaagcc ctgttcctca agatgaggag caaggctttt tgagtttcaa
     4621 ttattcttct gttccaagga aattttttgc aacaagggct gcaagaactc caccagcgat
     4681 tggtgcaagg atgaaaatcc aaacttgttg aagggctgcg ccgcctacca agacagctgg
     4741 tgccaagcta cgagctgggt ttactgaaag tccagtaatc ttcaatccga caagaatcat
     4801 cgccatcaat gacaaaccga ttaccaaacc agcaatcgcg ccattgccct tgctttctga
     4861 agtcacagtc atgataacca atacaaacaa gaaagttgcg atgacttcaa acaagaaacc
     4921 accaaagaca gtgacaccgt ttgccaaggc attttcacca agactagcag ttgacatacc
     4981 tgaattactc aagaggaaga agactgcgcc agaagcgatg aaagctccaa caacctgacc
     5041 aaggatgtag tttacaagtt ctgaagatga caaacgtttg tttacaaaca tagcaatcga
     5101 aacagccggg ttcaagtgag cacctgaaac agttccgatt gagtaggctg ccaccacgat
     5161 tgccaaacca aaggcaaagg cgattccaag gtgaccaagg ccatcaagac catttccaaa
     5221 aacaacagct cctgttccaa cgaacacaag catgaacgta ccgattaact cagcaacaaa
     5281 ttttttcatt ttctttctcc ttttttcaaa aactagatac tagtctatca aaagtaggaa
     5341 agggtttcaa gaaaattgat tggaaatttt ttgaaaatca tagaactatt agctaatctc
     5401 tagtattgaa aagactggat agcttctttc aactcatctt gtaaactatt tctctggtca
     5461 agttggacat agacttccac cagacaggat ctaaagttgg aaaatttgta aaaatcctcc
     5521 ctttcttcta tcggaaaatc aacagttttt atccaagaag ctacttgttc ttgcgctaac
     5581 ttcccttgta aaataggttc atagatcact cttgctaaac gccaatcctc atcatctgta
     5641 aagcgaatcg acattctttt aaataattgg ccaagtatct caaatacttc atgaactctg
     5701 tttttaggaa agcccggatg acaaaccacc tctgtcagta aatcggctcc atgtgcaaaa
     5761 gcatgaaccc aaccatactg acttgaaaaa ccccttgtat ccttttcttt tgaaagatag
     5821 tgcaagcctt gatttaaaag gacattacga atttctggag aaggatttcc caaatgatca
     5881 aacaaccact ggatttcttc ctggttataa tttggttttt cttctgctat ttttcttagt
     5941 aaatcttgat acatggtcaa tacctctaca tttctagcaa ctgttcaaaa aggcagtctt
     6001 aaatgactca atattgaatt ctcaattaaa tacaatctga tataaaatga cgtaaataac
     6061 tatcaatacc agttctacag taagttcaaa tttaacatca cgatcttcaa cgacattttt
     6121 gaaaatagct acaactaaga caaatagaat gacgcttaac aagcccataa acatcattct
     6181 aaaaaatttt tctattcccc tactctccca actcagcact ataggagata atctggtcaa
     6241 ctgtgtcaga caagaattgg atggtatcac ggagtggttt gtctgttgaa atatcagcac
     6301 cgataatcat ggctgactca agtggtgtct tgctaccacc tgatttgagg agattgagcc
     6361 agtcttcagc tccagtttca gaatgtttta gatgaaggta accagcagtc gagataacta
     6421 gtcctgctga gtaagtgtaa ctatacaagc ccatatagta gtgagcttgg cgcatccaag
     6481 tcagagttgc atcatcgtca atttcaatag catctcccca gaaatccgtc aaaacttcct
     6541 tcataatgct gttgagcttg cttgctccaa aggtctcccc ttcttcaatc aatgtataca
     6601 ccttacgctg gaaggcggct tccaagaggt gggtgataaa gttatggaag taggtgtctg
     6661 tcaagcgatg agccagagcg aagcgttttt gacgtgggtc attagactgg ttctccaagt
     6721 aatcactgag tagcaattca ttgaaggttg acggtgcttc aacatagtag gtcgacatat
     6781 gggcattgaa gtaactttga tgattgtctg aaaagatgaa ttgaccagaa tgcccgattt
     6841 catgaatcaa ggtatagaca tcgctcaaac ggcctgtcca gctcatgagt acataagggt
     6901 gtacgcgata tgggtccgcc gcataaccac cggaatcctt gccactgtta gcagcaaagt
     6961 ccacccagcg ctcttcttgg taacgagcaa cttcctgaca atattcttgc cccaaaggtt
     7021 ctaccgactt catgaccaaa tcataggcat cgtcaatagt cacttcagga ttcagggcgc
     7081 tgtccaagtc caatttccag tctgcaaagg tcatcttttc aagaccattt accttggcaa
     7141 catgcttgag gtatctctga gcgactggtg caaagtcctt catgatgagg tcaatctggc
     7201 ggtcaaacat gacacggtcc acttcttgtt cagctagaag atagtcaaag acagagtcgt
     7261 atcccttcat atcagccaag agtttttcag acttgacctg agccagatag gctgctgcag
     7321 ccgtattttg gtgcttacga agtccctctg agaaggaacg gaaggatttc tcacgaacct
     7381 cagcatcctc atggttttgg tagaaattct cataggtcac aaagctgttt ttgtaggtct
     7441 tgccatgggc ttcaaagtca gccatttcaa aatccccagc tcgcatctta gtataaatgt
     7501 cctgcggact gtagaaaact tcaccgagat ttgtcaaggc cttctccaca tctgccccta
     7561 agtagtgggc ttttttgatt ttagcctgac gaatggcagc tgttaaatgt ggcaatttac
     7621 ccaaacgatc caagacttcc tcgtctgctg ccaccaaggc atcgtcaaaa aaggtcaagg
     7681 ctacgctggc atctgtttca aattccatcc cagcttgagc aatatttgca aattcgtcat
     7741 tgctatagtc cgtcgtctga ggcataaaac catagttgcc aatatggctc atctgaatgt
     7801 agatctgttc caattccgca aaggccttct cgaaatcctc aaaagtgtga agattgccct
     7861 tgtaatcacg gctaaactgg ttgatgtctt cgcgagcttt ctcgattgca cgcaagaaat
     7921 cctcacggtc ttggtataga gctgttaaat cccaaagttc cttctctgga aattctgaac
     7981 ggtgtttttg ttccattttc ttcctcttat ttctctaatt ctactaaaac actaagggct
     8041 gataaggcgt aaagcggtgc tgtttctgct cttagaatgc gagggccaag tcctgccaaa
     8101 acagctccct tagcttcaaa attttcaatt tccgcaggtg acagaccacc ttctggacca
     8161 aagataaaga gcaatttggc tcctttctcg agtccagtaa ctgcttttat aagagcagcg
     8221 gcttctcctt ctttggccgc ctcttcatag gctactaaga tgcggtcaaa ctggtcaagt
     8281 tgggctagaa agtctgcttt attctcgaaa agatggatac ttggaacaac attacgctta
     8341 ctttgctctg ctgctccaag agcaattttt tctagttttt caaccttttt acccaatttc
     8401 ttgccatccc acttagcaac ggaccaatcg gcagggaagg cccaaatctg gctggcacct
     8461 agttccgtca ccttttgagt gataaactcc aacttatctc ccttgggaaa tccagatgcg
     8521 atggtcactt ggactggtag ttccacattg tcatttaatt cttggaccaa ctcaaactga
     8581 cgattttcca tatccagcac gcgcgccaag cgcttgatgc catcatcaaa gactaaggta
     8641 acctcatcct cttctttcaa gcgcataacc tgaaacatat gcttgctggt ttccctgtcc
     8701 tcgatggtga caggagagac tgcactcccc ttgacaaaat actgttgcat gctagcctcc
     8761 aatcacacct gaaatatcct tggtcttctt gaagacgcag gcattccatt ccccttgaat
     8821 catatgggtt tcaaggaaaa atccagctga ctcagccgac tggcgcacca tgtcccactt
     8881 gtccttgata atgccactca tgatgaggta gccttcatcc tttaccaagc gataagcatc
     8941 ctccgtcaga tgaatgagaa tatccgccaa gatattagcc acgatgacat ctgcttcaat
     9001 ctcaactccc ttaagcaagt ctcctgctgc tacatggata ttttccatac cagtgttgag
     9061 ctcaatattt tcctgagcga cacgaaccgc cacatcatcc aagtcatagg cgaaaatctc
     9121 cttggcacct aggagtgagc ttgcaataga aagaacccct gaaccagtcc ccacatctag
     9181 caccgtttcg ccaccacgaa gaacctgttc caaggcaaaa aggctcatct tggtagttgg
     9241 gtgggttcca gtaccaaaag ccatgccagg atccagcttg ataatttttt ctcccgcagt
     9301 cgcctcatag tctgtccaag agggaacgat ggtcaaatca tgagtgatgc gagcaggttc
     9361 atagtatttc ttccagttgt ctgcccagtc ttcctcagcc aaggcagtcg tacctatttt
     9421 taactctccc aaatccataa aatccgtcaa ttctgctaag cgagcctgca agtccgcctc
     9481 aaccactgtc atatccaccg tgtcagggta gtaggctgtc actacgattt cttcttgctg
     9541 ctccacctct gggaaaatct cgccaaaacg atccacattt cccatatagt ccatgctgtc
     9601 ttcaatcgcg actccttgcg ctcccagctc aatcaagaga ttggaaacca actcctctcc
     9661 ctcacgcttc actgtaactt ttaactcttg ccatgtttcc attattaaga taccaagccc
     9721 gtaaaacaca aaaccaaaat aggaaattct ctgaagacgc ttgtgtctaa gagaagttta
     9781 tctttttggc acagtgttta gggcgggttc agtttagaaa tgtaactgaa ccatcctttc
     9841 taatcactta cttttaaata atcttttaat ctctcttgca actgaggcac aacttgactg
     9901 gaactaagaa attcctcaac attcatcagc tgatagccct gtccttcatc tccgaagatg
     9961 atattgtcaa attgttcttg tcttagctga ccaaccataa agaccgattt cttgccttta
    10021 aaaattacgc taggataaat cttgctccaa agcagacagt cttcatctaa atgaattccc
    10081 agttcctcat aaacttcacg ccgagcgcat tcaaaagggc tttcgtcccc ttcacggcca
    10141 ccacctggca actcccacat gttgggacaa gggatatcgt ccttgtcatc acgcaaaatc
    10201 gtcagtagct tatccccaca aaagagggca atcttgcaac cttggaaatc agaaatttct
    10261 agttccatct tcagttcctt ctaacatttc cttttccagc tctgctaaca agttttcata
    10321 atagcgtttc tcgtccctca acattcgact actatccatt ttctgtctag caatcttgag
    10381 agccttacga gttcgatcta catctttctt cacctttaat tgataccagg cttgtatcac
    10441 ttgaagattg gacagtttga gagacagaaa cgatttgacc tgtcgaatac tagcatattg
    10501 ctccgcttgc tcaaaatctc cttccaacaa ggcgatatga agcagggata gttgggcaac
    10561 tgtctgcatc atcggagtag ttgtcctctc aagtaatgct tgaaactgct gtttagctac
    10621 ttcttccttc ccttccaaaa tggaaacttc accttgcata cctaatacac catccgcaaa
    10681 actccctcgt gcatcctcag gaactgcttg aacaaagtct ttcaaatcat attcttgagg
    10741 agccagcaaa gtttgagcag aatgtctcaa taccaggtag gcgtatttgg tattttcagg
    10801 gtgttgtagt aattcccaaa tttttgctcc atcggtgatg tcgactggca aaatgttatt
    10861 taggaagaaa gataaattaa gaaaaatcca agtccctgca aaataccagc ttcttgtcaa
    10921 aaatccaaac actatcgcca ataatatcaa gccgagatga accatcaagc ctcctgaaag
    10981 catcaggatg attctttgat cgctttcatc ctcttttaaa ccaatgtatt gagcaccaac
    11041 atttttcaga atggctgttc tactaagatg aaacctgcct gactttttgg tcaaaataaa
    11101 atgtcctaat ccaaaagcca ccagccgata gcctgtcaag tagccacaaa aagcatgacc
    11161 cagctcatga agaataaaga ttaaatacat gcttagaaga gcgaaggcat aaccaaaagt
    11221 aaaggctaaa actgcggaat accccaactc tgcaaatgcg attgttccac aagcaaaagc
    11281 tagcataata aagacaacag ctagcacata aaccaaataa gtcccaattt tcttcataac
    11341 acctccaacc aactcctagt atcttggata aggataaaat tctccctctt ccaagccaac
    11401 ttttccttct tcaaagactt cttggttcca ttccatgaca aattcctctg cttctgggtc
    11461 ttccaaaaag tccatgagga catctagccc aacctcagca gtatctttaa ggaaaagcac
    11521 aaaataagct aaaaattcac gggaaaatcc ttttttaggc aggtaaggaa taacagtcaa
    11581 atagtcttcc tcattgactg ttgacttagc aggattgtag aaaaggaccg cttcctcaaa
    11641 aagaatgtca tctgatgaaa cctctccgtc ttcatccacc atctccacac ctgcagcatt
    11701 ttgcgcttcc aatagaaaac tcacttctac cgcatggttg cgtttgtccc agctaatctc
    11761 aaagtcaaag ggaaagttct tgtccaactc ttcctctaaa acatctaaaa atccgtatgt
    11821 tgccattttg tcctctttct atgcgactct ttaatcgccc cgattgctcg gaaatatgct
    11881 aaaatagata ctaccatctt accacaaaat tattttatgt cctaattata ccatattacc
    11941 tcatttaaac ccttggtatc agtgattttc ttaaaagtct gatttcttca tttctcataa
    12001 aaatcaatat aaaaagccct cgaaagggct aataaatcta taaaatcaat aggcgagtaa
    12061 ctagcacaag tggacgtgct tttttattga ctattaccac gataccacgc ttaatcttag
    12121 gcttgaactt tcttatctgc aatagcgtct gtcaaagtct gagaaaagtt aagtcccatt
    12181 tctcgtccca acttatctgc ccattttggt atggtcaaag tctttttaat gggttcctga
    12241 cttcctaggt attctgatac atcaacagat accatagaaa taaaagattt atcaaggtca
    12301 taggttgaca cgaaatcttc atcatcttta aaaggatcat tatcaattaa agacaagcta
    12361 ttgatatctg atggctgagg taactctcca tcactctcta tcaaatctgc aacagttatc
    12421 cctagccact ccgaccccat agccaaagcc tcagaaatcc cctctccttg tgtagctgag
    12481 tattcaaaat ctgggaaatg gacaaaataa gtcgcttctg ttccgtctgt gtcgtcataa
    12541 taaaataaag ctggatacgt aactaacatt tcactacctc catatcaaaa agcagggact
    12601 gaattttaca acccagcttg ctttcctatc cctctttcag tgtacttatt cagctcacca
    12661 tgaaggattg tgataggtct ttccccttgc ttctcgattt taatatggga gcctttaccg
    12721 cctctagtct ttatccaacc atgggccgta aagagtttaa ccatctcttt ttgtgtcata
    12781 ggcatagcgc ttttacctcc tgacaacacc attataacac gtgttacacg tattgtaaag
    12841 gagtgatact tattattcta ttatacataa aagcccctag atgtggttct aagggaaacc
    12901 aatttattca gacctatttt tctaatgagt agtaaaaact gcttctttat cgagcaattc
    12961 atcatctgta tagtcaattg taaaagtatc tcgatctaag acagattgag gcggagttga
    13021 atgaatcata ggaccactgc gtactctata ttttttatct ccaattttta caaactgata
    13081 ctcttcgaaa atcaaattca aaccacgtca acgtcgcctt accgtactca agtacagcct
    13141 gcggctagtt tcctagtttg ctctttgatt ttcattgagt atgattaact ctcaagtctt
    13201 cgaaatcagg attttcaaca gttattacaa ggaggcgatt tactacttca aaaacatcaa
    13261 ttattctatt tttcatattt tttcaaccca ttattagaat gaacttcttg gtaagcaaaa
    13321 tcaagtttag atttaatgtt ttcgtacaaa tctaaaatct cttttggagt atcttcccgg
    13381 aagaaaagtt ttcttttccc tgaaataact tgatcactaa gaatccaatg acgaatttgt
    13441 tttgtaaaaa t
//
LOCUS       DAVBDR010000056        12573 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.056, whole genome shotgun sequence.
ACCESSION   DAVBDR010000056 DAVBDR010000000
VERSION     DAVBDR010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12573)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12573)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12573
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.056"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            complement(251..433)
                     /locus_tag="VQ540_001711"
     CDS             complement(251..433)
                     /locus_tag="VQ540_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2545479.1"
                     /translation="MAVIFKNVLIEEKTEEEKQHILSILNGEYDLSDDVSCRLRRLNE
                     ESKRLEVFVKETNSLV"
     gene            complement(649..1881)
                     /locus_tag="VQ540_001712"
     CDS             complement(649..1881)
                     /locus_tag="VQ540_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HET2545480.1"
                     /translation="MKIAVAGTGYVGLSIAILLAQHHQVVAVDIIPEKVELINKKKSP
                     IQDDYIEKYLAEKELNLVATLNAEEAYENADFIVIAAPTNYDPKKNFFDTSSVEAVIE
                     AVMKYNPDAIIIIKSTVPVGYTKSVRRKFLTDNIMFSPEFLRESKALYDNLYPSRIII
                     GTDKDDKDLVKSAEIFVKMLQEGAVKENIETLYMDFTEAEAVKLFANTYLALRVSYFN
                     ELDTYSEMKGLDTQAIIDGVCLDPRIGSHYNNPSFGYGGYCLPKDTKQLLANYSDVPQ
                     EMITAIVQSNRTRKDYIADRILDLAGSYVGNDFYKPDKEKEIVVGIYRLTMKSNSDNF
                     RQSSIQGIMKRLKAKGVTIIIYEPTLESGTTFYGSQVVNDFEIFKKSSQVIVANRFDE
                     TLEDVRGKVYTRDIFKRD"
     gene            complement(1910..2980)
                     /gene="gla"
                     /locus_tag="VQ540_001713"
     CDS             complement(1910..2980)
                     /gene="gla"
                     /locus_tag="VQ540_001713"
                     /EC_number="5.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001214397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucuronate 4-epimerase Gla"
                     /protein_id="HET2545481.1"
                     /translation="MRGKTILITGVAGFIGSNLVRKLLELEGTMTIIGLDNLNDYYDI
                     ALKDYRLLQLNKLIQDYPEKNWIFIKGDIADKMLINKIFKSYHPQIVVNLAAQAGVRY
                     SITNPDVYIESNIVGFHNVLEACRHSYEIYDGGVEHLVYASSSSVYGGNKKIPFATED
                     KVDNPISLYAATKKTNELQAYAYSKIYNIPSTGLRFFTVYGPAGRPDMAYFGFTDKLR
                     SGSDIEIYNHGNCKRDFTYIDDIVEGIVRVMQSAPKKLVGSDNLPLAPYKVYNIGNSK
                     PENLLDFVDVLQQELIKAGVLPENYDFDSHKKLVPMQPGDVPVTYADTSDLERDFGFK
                     PKTSLREGLRKFAEWYKDYYNV"
     gene            complement(3048..4217)
                     /locus_tag="VQ540_001714"
     CDS             complement(3048..4217)
                     /locus_tag="VQ540_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HET2545482.1"
                     /translation="MRLSKKYWFALTSKFLLILLTLLSSIIINRGLGVEKKGDYAYVM
                     NLVEIFYILGGVGLGQAYSTFKRNHSNEYQNKFVFLTFIQGLLFGIIGLIIVLADVPI
                     DYGGVIIVLSSLSIMRTNLTMIAVIENSIKRNKIVLGVSVVYSVMLVLLLLFHLVSIE
                     MVFLVYAINEFLRIILFLYYYNMFPVFEHISIKEFFTIYKFGFLSMILTLLITFNYSI
                     DIIMLKQMSSSYNVGIYSVAVTFSNMFLMVPDSFKEILFGDSAKRTFEKNKAINAIKV
                     SFLFMILLIIGFLSFGEFAITLLYGSSYIKAFPITLVIFLGSLSMIFFKILQPIYISQ
                     GKQSVAIKILSVSALINISLNWYLIPNYQITGAAIASAISYTVCGLFFIIDYLRN"
     gene            complement(4403..5707)
                     /locus_tag="VQ540_001715"
     CDS             complement(4403..5707)
                     /locus_tag="VQ540_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide repeat unit polymerase"
                     /protein_id="HET2545483.1"
                     /translation="MKFSLQSNDIKNKIILLVGVVFSGTLILCSENNDVTIPLFSMIF
                     LSFMAMIIVKFNIFHPYVWYSSFFTIYSISYPLLYRMEYINYGYTKDLIFMQWLALAT
                     LLLTLPSKAIVLSERKINLNNNNYLLFLNNMNTFITTVAIIYLLGSGFRNKGEIYSGA
                     NIVIMLVFSLVYFMILIHTYQLFIQLSTKKWRLLNCNTNTAIVICLFSIVTGERDYMF
                     TLFILDVIILFYFHKIKRFYLVMLVPLAALLIPLSAVFKYTLLSGQVSSINTNNIWFD
                     LLDGEFVSASRNLQILILHNMGNYFEGRSFFNDIVRIFYNTGYSNQTWFMDTFFPNVH
                     STKYGFTLVGEGYVNGGYFGIVMIFMLTGFLMRFLYINAQRNIYGMLIYLYMIPIFIY
                     STRADFANILSPLLKYAILGTLVIVFINRMVLISPLDEMGGE"
     gene            complement(5824..6978)
                     /locus_tag="VQ540_001716"
     CDS             complement(5824..6978)
                     /locus_tag="VQ540_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HET2545484.1"
                     /translation="MKVFIATEFRCTIYKNEIYLKPKAYFIYERYAKAFGEIVLCSRY
                     EKVESYPEGYHKANFINKFIPIEGLHQVLFGQNKNKIIEGMIDSDLIVVRIPSIIGSK
                     TADYALKIGKPYLTEIMGDAWDSYWYHSLKGKLLAPYIYAKTKSIVKNANYCIYVTEK
                     YLQDRYPNIKSNIVASNVNITSVENRSLKSRLYKLKKFNPQKISIMTTASVNVRAKGH
                     RFVLEAMKRLEIQGILLDYYLAGDGDQSFLKKKAEELGVANRIHFLGELTTSQIYEYL
                     DKVDLYIQPSLQEGLPRAVIEAMSRACPCIGSNKAGIPELLGPHCLFTPSSSQAIAGS
                     IIDFISMDKEKMVIKQFEFSKKFLSSVLNKRRSDYFAQIRRELNNSDGLD"
     gene            complement(6975..7526)
                     /locus_tag="VQ540_001717"
     CDS             complement(6975..7526)
                     /locus_tag="VQ540_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase"
                     /protein_id="HET2545485.1"
                     /translation="MNRIIKNIVGLLRANICLILLKVCRNKDLTFHYFLKFGKNVTVE
                     QESNAKLILGKKIRVNAGGVLKVRKGAKLKISDDVFLSNNCMIACRKYIDIKSGVKCG
                     PGVLIYDHDYDVSVPGGLKAKKFKTAPVMIGENVWIGANSIVLKGVSIGENSVVAAGS
                     VVTKDIPADTIFIQKRLSREMKL"
     gene            complement(7519..8655)
                     /locus_tag="VQ540_001718"
     CDS             complement(7519..8655)
                     /locus_tag="VQ540_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001053205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HET2545486.1"
                     /translation="MNLQKKKIMLITNHDDDIYCFRKEVIESLVEYGYEVLVSCPYGD
                     KIELMKSIQFEYEDITIDRRGINPLKDIRLFLSYIRLLRKYRPDVVLTYTVKPNVYAS
                     LAATILGIKYINNVTGLGSVLTMGSCVRSLVLLLFRISFRKSNCVFFQNEYNMKMLKT
                     LGLILGDSKLIPGSGVNIEKYPVQQYPNGGNGIQGETIVFNFIGRILKEKGIDTYLAA
                     AQIIKSRYPKTEFNIIGFIEPTESNYELKICDLEKKGIVYYLGQQKDVIPHITRSHAI
                     IHPSVYGEGMSNVLLENASSGRVLITTDNPGCKEIVKDRETGYIFQGGNVEELVSILE
                     VFLGLENEKRKEMGLQGRMYIEQYFSRQIIIDAYLDKIKGALDE"
     gene            complement(8796..9461)
                     /gene="cpsD"
                     /locus_tag="VQ540_001719"
     CDS             complement(8796..9461)
                     /gene="cpsD"
                     /locus_tag="VQ540_001719"
                     /EC_number="2.7.10.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis tyrosine autokinase
                     CpsD"
                     /protein_id="HET2545487.1"
                     /translation="MPTLEIAQKKLEFIKKAEEYYNTLCTNIQLSGDKLKVISVTSVN
                     PGEGKTTTSVNIAMSFARAGYKTLLFDGDIRNSVMSGFFKSREKITGLTEFLSGTADL
                     SHGLCDTNIENLFVVQSGSVSPNPIALLQSKNFNDMIETLRKYFDYIIVDTPPIGIVI
                     DAAIITQKCDASILITATGEANKRDVQKAKQQLEQTGELFLGVVLNKLDISVDKYGVY
                     GRK"
     gene            complement(9471..10163)
                     /gene="cpsC"
                     /locus_tag="VQ540_001720"
     CDS             complement(9471..10163)
                     /gene="cpsC"
                     /locus_tag="VQ540_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000664160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     CpsC"
                     /protein_id="HET2545488.1"
                     /translation="MKEQNTLEIDVLQLFRALWKRKLVILLVAIITSSVAFAYSTFVI
                     KPEFTSTTRIYLVNRNQGEKPGLTDQDLQAGAYLVKDYREIVLSQDVLEEVISDLKLD
                     LMPKGLANKIKVTVPVDTRIVSVSVSDRVPEEASRIANSLREVAAQKIISITRVSDVT
                     TLEEARPAISPSSPNIKRNTLIGFLAGVIGTSVIVLLLELLDTRVKRPEDIENALQMT
                     LLGVVPNLGKLK"
     gene            complement(10172..10903)
                     /locus_tag="VQ540_001721"
     CDS             complement(10172..10903)
                     /locus_tag="VQ540_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein phosphatase CpsB"
                     /protein_id="HET2545489.1"
                     /translation="MIDIHSHIVFDVDDGPKSREESKALLAESYRQGVRTIVSTSHRR
                     KGMFETPEEKIAENFLQVREIAKEVADDLVIAYGAEIYYTLDALEKLEKKEIPTLNDS
                     RYALIEFSMHTSYRQIHTGLSNILMLGITPVIAHIERYDALENNEKRVRELIDMGCYT
                     QINSYHVSKPKFFGEKYKFMKKRARYFLERDLVHVVASDMHNLDSRPPYMQQAYDIIA
                     KKYGAKKAKELFVDNPRKIIMDQLI"
     gene            complement(10905..12350)
                     /locus_tag="VQ540_001722"
     CDS             complement(10905..12350)
                     /locus_tag="VQ540_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000091082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HET2545490.1"
                     /translation="MSRRFKKSRSQKVKRSVNIVLLTIYLLLICFLLFLIFKYNILAF
                     RYLNLVVTALVLLVALVGLLLIIYKKAEKFTIFLLLFSILVSSVSLFAVQQFVGLTNR
                     LNATSNYSEYSISVAVLADSKIENVTQLTSVTAPTGTDNENIQKLLADIKSSQNTDLT
                     VNQSSSYLAAYKSLIAGETKAIVLNSVFENIIESEYPDYASKIKKIYTKGFTKKVEAP
                     KTSKNQSFNIYVSGIDTYGPISSVSRSDVNILMTVNRDTKKILLTTTPRDAYVPIADS
                     GNNQKDKLTHAGIYGVDSSIHTLENLYGVDINYYVRLNFTSFLKMIDLLGGVDVHNDQ
                     EFSALHGKFHFPVGNVHLDSEQALGFVRERYSLTDGDRDRGRNQQKVIVAIIQKLTST
                     EVLKNYSSILQGLQDSLQTNIPIETMIDLVNTQLESGGNYKVNSQDLKGTGRMDLPSY
                     AMPDSNLYVMEIDDSSLTVVKAAIQDVMEGR"
BASE COUNT         4238 a         2434 c         1655 g         4246 t
ORIGIN      
        1 aattcactta cttcatatta catttagcat gaaatgaaat aagcgaattc tactttgttt
       61 gcatacaatt aaaaatcaat tcctaaggat gttttaaata actgtgtaaa aggcataatt
      121 tcaccatttc ttagtttttc aatgctaaat tacatagtaa ctggagagct attagaaatc
      181 tctaacttcc tcatagttaa aaaatgacaa tgagatactt attgatttca attcattaac
      241 agaatacgaa ctagacaagt gagttcgtct ccttaacaaa cacttccaag cgtttacttt
      301 cctcattcag tcgtcgtaat ctacaactta catcatcaga taagtcatac tcaccattta
      361 gaatagatag aatatgttgt ttttcttctt cagtcttctc ttcaataagc acatttttaa
      421 aaattactgc cattatcagc acctcacttc gaaggaatat atgcaactat atcctattaa
      481 gtcaatctct actgacaaaa gaagtatatt tacttcacta agtgcgagcg agaatataga
      541 aatatcttta ttgttttaga tgagttgtcg ctatcctcca gctagttttt aactattcta
      601 tcattcaaat gatatagatt attagggact agaaatatac aaattgattt aatctctctt
      661 aaaaatatcc ctagtataaa ctttacccct cacatcttct aaagtctcat caaaacgatt
      721 tgcaacaatc acttgactag atttcttaaa tatttcaaaa tcattaacta cttgactacc
      781 atagaaagta gtaccacttt caagagttgg ttcgtaaata ataatagtaa caccttttgc
      841 tttcaaacgc ttcataatac cttgaataga agattgtcta aaattatctg aattactttt
      901 cattgttaaa cgataaattc ctacaacaat ctctttttct ttatctggtt tatagaaatc
      961 attgcctaca taagatccag caagatctaa aatacgatct gcaatataat cttttcttgt
     1021 ccgattactt tgtactatag ctgttatcat ttcttgtgga acgtcagaat aatttgcaag
     1081 aagttgcttg gtatctttag gaagacagta acccccataa ccaaaagaag gattattgta
     1141 gtgagaacct attctcggat ctaaacaaac tccatcaata atcgcttgag tatctagtcc
     1201 tttcatctca gaataagtat ctaactcgtt aaaataggaa acccggaggg caagataggt
     1261 attagcaaaa agttttactg cttcagcttc tgtaaaatcc atatacaatg tttcaatatt
     1321 ttctttcact gcaccttcct gaagcatttt tacaaaaatt tcagcagact ttaccaaatc
     1381 tttatcatct ttatctgtac ctataataat tcgactcgga tataggttat catataacgc
     1441 ttttgactcc cgtaaaaact caggactaaa cataatattg tctgtaagaa atttcctccg
     1501 tactgacttt gtatatccaa caggaacagt acttttaatt attataattg catcaggatt
     1561 atatttcata actgcttcaa tgacagcctc gactgaagat gtatcgaaaa aatttttttt
     1621 cggatcataa ttagttggag ccgcaataac tataaaatcc gcattctcat atgcttcctc
     1681 tgcattcaat gtagctacga gattcaattc tttttccgcg agatattttt ctatataatc
     1741 gtcttggata ggggacttct ttttattgat taactcaact ttctcaggaa tgatatctac
     1801 ggcaacaact tgatgatgtt gagccagtaa gattgcaata gataatccaa catatcctgt
     1861 acctgctact gctattttca taattttttc ctttctcaaa acactctcgt tatacattat
     1921 agtagtcttt ataccactct gcaaactttc tcaaaccttc tcgtaaagaa gtttttggtt
     1981 taaaaccaaa atctctctct aaatcacttg tatctgcata agtaacagga acatcgcctg
     2041 gttgcatagg aactaatttt ttatgactat caaaatcata attttccggc aaaactcctg
     2101 ccttgattag ctcctgttga agaacatcca caaaatctaa caaattttcg ggtttactat
     2161 tcccaatatt gtacacttta tatggggcta acggtaaatt atcagatccc actagtttct
     2221 tcggagctga ttgcatgacc cttactatcc cctcaacgat atcatctata taagtaaaat
     2281 ctcgtttaca attaccatga ttataaatct caatatcgga accacttcgc aatttatctg
     2341 taaatccaaa ataggccata tctgggcgcc cagcaggacc ataaactgta aaaaagcgta
     2401 agcctgtcga aggaatattg taaatctttg aataagcata cgcttgaagt tcatttgttt
     2461 ttttagtcgc agcatatagt gaaataggat tgtctacctt atcttctgtt gcaaacggga
     2521 tttttttatt tccaccatat accgatgagg acgatgcata aactaagtgt tccacaccac
     2581 catcatatat ctcatacgaa tgacgacaag cttccaacac attatgaaag ccaacgatat
     2641 tactttctat atatacatct ggatttgtaa tggagtagcg tactcctgcc tgggcagcta
     2701 gattaacaac aatctgagga tgataactct taaaaatctt attaataagc attttatctg
     2761 caatatcacc cttgataaat atccagtttt tttctggata atcctgaatt agcttattaa
     2821 gttgaagcaa tcgataatct ttaagtgcaa tatcatagta atcattcaaa ttgtccaaac
     2881 caatgattgt catcgttcct tctaattcca ataatttcct aaccagattt gatccaataa
     2941 aaccagctac tcctgtaatt agaattgttt ttcctctcat atcataatac ctcttgttat
     3001 ttttatattt tcgtccacta atacacattc tttaacaact attataatca atttctaaga
     3061 taatctataa taaaaaacaa accacataca gtataagaga ttgctgatgc tatcgcagct
     3121 cctgtaattt ggtagttagg aattaagtac cagtttaaac ttatatttat caaagccgac
     3181 acagataaaa tttttatagc tacactctgt ttaccctgag atatataaat tggttgtaaa
     3241 attttaaaga aaatcatcga taagcttcct aaaaaaatga ctaatgttat aggaaatgcc
     3301 tttatataac tggaaccata aaggagcgta atcgcaaatt ctccaaaaga aagaaatcca
     3361 ataattaata aaatcataaa tagaaatgat acttttattg catttattgc tttatttttc
     3421 tcaaaagttc ttttagccga atcaccaaat aaaatctctt taaatgagtc tggaaccatc
     3481 aaaaacatat tagaaaacgt aactgcgaca ctgtatatac ctacattata actactagac
     3541 atttgcttca acattatgat atcaatacta taattaaatg taattaatag agtaagaatc
     3601 atagaaagaa atccaaactt atatatagtg aaaaattctt taatactaat atgttcaaaa
     3661 actgggaaca tattgtaata gtataaaaat aaaatgatac gtaaaaattc attaatagca
     3721 tataccaaaa ataccatctc tatagaaact aaatgaaata gtaacaacaa tactagcata
     3781 acggaatata ctacgcttac tcctaataca atcttattcc tctttatact attttctatt
     3841 actgcaatca tagtaagatt tgttctcata atagatagac tggacaaaac tattattacc
     3901 ccaccataat ctatcggaac atcagctaaa actattatta aacctattat tccaaacaat
     3961 aatccttgaa taaaagttaa aaaaacaaat ttattctgat actcattaga atgattcctt
     4021 ttaaaggtcg agtaagcctg acctaaacca actccaccta aaatataaaa aatttctact
     4081 aagttcatta cataggcata atctcctttt ttttcaacac ctaatcccct attaattata
     4141 attgaggata aaagtgttaa taagattaac aaaaatttac tcgttaaagc aaaccaatat
     4201 ttcttagata gtctcactta ttttctccgt atgttaaatt ttataacagt aaatttaaaa
     4261 ttatagtata ttgaaataga atatgaacaa aacgattagg gaatttaaag taatttataa
     4321 aaattcttta gaagctgcat tgtactactc caacttcaaa ccactatagt atcaaaaagt
     4381 ataccccacc tttttaaata aactactcac cacccatttc atccaatggt gatatcaaca
     4441 ccattctatt gataaaaaca ataaccaatg ttcccaatat agcatattta agtaatggag
     4501 ataatatgtt agcaaaatca gcacgagtag aataaataaa aataggtatc atatacagat
     4561 atatcagcat cccgtatata tttctttgag cgtttatata aagaaatctc atcaaaaagc
     4621 ctgttagcat aaaaatcatt acaattccaa agtatcctcc attcacatat ccctctccca
     4681 caagagtaaa accatatttg gttgaatgta cgtttggaaa aaaggtgtcc ataaaccaag
     4741 tttgattaga ataccccgta ttataaaaaa ttcttactat gtcattaaaa aaagaacgac
     4801 cttcgaaata attgcccata ttatgtaata tcagaatctg taaattacga ctagctgata
     4861 caaactcacc atctagcaaa tcaaaccaaa tattatttgt atttatagat gaaacttgcc
     4921 cacttaataa agtatattta aaaactgcag ataacggaat cagtagtgcc gcaagcggaa
     4981 ctaacattac aagataaaaa cgttttattt tgtgaaagta aaataatata atcacatcaa
     5041 ggatgaataa agtaaacata taatctcttt cccctgtaac gatagagaag agacagataa
     5101 ctatcgctgt gttagtatta caatttagta gtctccattt tttagtactc aactgtataa
     5161 atagctgata tgtatgaatg agaatcataa aataaaccaa agaaaatact aacattatca
     5221 caatattggc acctgaatat atttcccctt tatttctaaa accacttcct aatagatata
     5281 taattgctac tgttgtgata aacgtattca tattattgag aaataataaa tagttattgt
     5341 tatttaggtt tattttcctt tcgcttaaca caatggcttt agaaggtaga gttaacaaca
     5401 aagttgccaa agccagccat tgcatgaaaa tcaaatcttt tgtataacca tagtttatat
     5461 actccattct atagagtagc gggtaagaaa tagaataaat agtaaagaag ctactatacc
     5521 acacataggg atgaaaaata ttaaatttca caattatcat tgccataaaa cttaaaaaaa
     5581 tcattgaaaa taatggaatt gtaacatcat tattttcact gcataaaatt aaagtccctg
     5641 aaaaaactac acctactaga agtattattt tattttttat atcatttgat tgtagactaa
     5701 acttcattta cttttttcct ttaactaata atttaaacgt aatgcgtatt caaaaatttg
     5761 attggctatg tagtcagttt ttatagcata tttaatatat cgaaacggat tttccatcgc
     5821 attttaatct aaaccatcag aattatttaa ttctcttcta atttgagcaa aatagtcact
     5881 tctgcgttta tttaatacac tcgaaagaaa tttttttgag aattcaaact gttttatcac
     5941 catcttttcc ttatccatac taataaaatc tataatagat cccgcaatcg cttgtgaaga
     6001 ggatggagta aatagacaat gtggccccag caactctgga attcctgctt tattagaccc
     6061 tatacaaggg caagcacggc tcatagcttc aattaccgca cgaggtaacc cttcttgtaa
     6121 acttggttgt atatataaat caactttatc caaatactca taaatttgtg atgtagtcaa
     6181 ttcccctaaa aaatggattc tattcgctac tcccaattcc tctgctttct tttttaagaa
     6241 actttgatca ccatcacctg ctaaataata atccaacaaa ataccttgta tttctaatct
     6301 cttcattgct tccaatacaa atctatggcc cttggctcgt acattcacag atgctgttgt
     6361 cattattgaa attttttgag gattaaattt tttcaactta taaagacggc tcttcaaaga
     6421 tctattctct acagaggtaa tattaacatt tgaagcaacg atattagatt taatattagg
     6481 atatctatct tgtaaatatt tttctgtcac gtatatgcaa taattagcgt tttttacaat
     6541 tgatttagtt ttggcgtata tatatggagc taataatttt ccctttaaac tatgatacca
     6601 gtaagaatcc caagcatccc ccattatttc tgtcagatac ggcttaccta tcttcaatgc
     6661 gtagtctgca gtttttgatc caattataga cggaatacga acaactatta agtcgctatc
     6721 aatcattcct tcaataatct tatttttatt ttgaccaaat agaacctgat gtagaccttc
     6781 tatagggata aatttattaa taaagttcgc tttatgatat ccttcagggt atgattccac
     6841 cttctcataa cgactacata gtacaatctc tccaaatgct ttagcatagc gctcataaat
     6901 aaaataagct ttcggtttta aatatatttc atttttatag attgtacatc taaattcagt
     6961 cgctataaat actttcataa tttcatctcc cttgataaac gtttctgaat aaatatagta
     7021 tcagctggaa tatcctttgt tacaacactt cctgctgcaa ccacactatt ctcaccaata
     7081 ctcactccct tcaagacaat gctgttagct ccaatccaaa cattttctcc aatcataact
     7141 ggggccgtct taaatttttt tgctttcaat ccacctggaa cactaacatc atagtcatga
     7201 tcatatataa gtactccagg accacatttt actccagatt taatatctat gtatttacga
     7261 caagctatca tacaattatt actcaaaaat acatcatcag aaatcttgag ttttgctcct
     7321 tttctaactt tcaatactcc cccggcgttt actctaatct tttttcctaa gattaattta
     7381 gcattagatt cctgttcgac agttacattc tttccaaatt ttaaaaaata atgaaaagta
     7441 agatccttgt ttcgacacac ttttaataat atcaagcaaa tatttgcacg aagtaaacca
     7501 acaatatttt ttataatcct attcatctaa agctcctttt attttatcta aataagcatc
     7561 tataataatt tgacgagaaa aatattgctc tatatacatt ctcccttgaa gtcccatctc
     7621 ttttcgtttt tcattttcta gacctaaaaa aacttccaat atagagacta gttcctcaac
     7681 atttccccct tgaaatatat agcctgtctc tctatcttta acaatttctt tgcaacctgg
     7741 attatctgtc gtaattaaaa cacgtcctga actagcgttt tctagtaata cattgctcat
     7801 tccttcacca tacacactgg gatggataat tgcatgggaa cgggtaatat gaggtatcac
     7861 atctttttgt tgtcccaaat aataaacgat tccttttttt tctaagtcac aaattttaag
     7921 ttcataatta ctctctgtcg gttctataaa gccaataata ttaaactctg ttttgggata
     7981 tcgactctta ataatttggg cagcagccag ataagtatct ataccttttt cttttaatat
     8041 cctaccaata aaattaaaaa cgattgtttc tccttgaatt ccatttccac catttggata
     8101 ctgttgcaca ggatactttt caatgttcac tcctgaccca ggtatcagct tagagtcacc
     8161 caaaatcaag ccaagagttt ttaacatttt catattatat tcattttgaa aaaaaacaca
     8221 atttgatttc ctaaaagaaa ttctaaacag taataacacc aggcttctta cacaagaacc
     8281 cattgttaag acactaccta aacctgttac gttatttata tattttattc ctaaaattgt
     8341 tgcagctagg ctagcatata catttggttt cacggtatat gtcaagacta catccggtct
     8401 atattttctc aataatctta tataactaag aaatagacga atatctttta aagggtttat
     8461 tcctcttcta tcaatagtaa tatcttcata ctcaaattga atagacttca tcaactctat
     8521 cttatctcca taaggacatg acactagcac ttcataccca tactcaacta gtgactctat
     8581 aacttctttt cgaaaacaat agatatcatc gtcatgatta gttattaaca taattttttt
     8641 cttttgtaaa ttcatcaaaa taatcttcct aaaatataat taaccgctac tccattatcc
     8701 tttacaacta tcattttaaa aatagtaatt ttctataagt aattgtttcc aaattgtgac
     8761 actttaaaat tctatacaca tatagaactt acaaactatt tacgaccgta aactccatac
     8821 ttatcaaccg agatatccaa tttatttaaa acaactccca ggaacagttc ccctgtttgt
     8881 tctaattgtt gtttcgcttt ttggacatca cgtttattcg cctcacctgt tgctgttatc
     8941 aagatggacg catcacactt ttgagtgata attgccgcat caataacaat tccaataggt
     9001 ggtgtatcaa caatgatata atcaaaatat ttacgcaatg tttcaatcat atcattaaaa
     9061 tttttacttt gtaacaaggc tatagggttt ggtgatacag atcccgattg aactacaaat
     9121 aaattttcaa tatttgtatc acataaaccg tgagataaat cagctgtccc agataaaaat
     9181 tctgttagcc ctgtaatttt ttcacgagat ttaaaaaatc ctgacataac tgaatttcga
     9241 atatcgccat cgaacaaaag agttttatag cctgcacgcg caaatgacat tgctatattt
     9301 acggaagtag ttgtttttcc ttcccccgga ttaacagaag taacggaaat tacttttagt
     9361 ttatctccgc tcaactgtat atttgtacac aaggtattgt aatattcttc tgccttctta
     9421 atgaactcca gttttttttg tgctatttct aatgtcggca tctctctctc ctatttcaac
     9481 ttacccaagt ttggtacaac tcccaaaagt gtcatctgca gtgcattttc gatatcttcc
     9541 ggacgtttca cacgagtgtc caaaagttca agaagaagaa ctataacact agttccaatc
     9601 acccctgcca aaaaaccaat tagtgtattg cgtttaatat ttggcgaaga cggtgatatc
     9661 gccggtcttg cctcctccag tgttgtcaca tcagaaacac gagtaatact gataattttt
     9721 tgagcagcta cttctcttaa agagttagcg atacggcttg cctcttcagg aactcgatca
     9781 ctaactgaaa cagagacaat acgggtatca actggtactg ttactttaat tttattagcc
     9841 aaaccttttg gcatcaaatc tagtttcaaa tcagaaataa cttcctccaa aacatcctgc
     9901 gataggacaa tttcacgata gtctttaacc aagtatgctc ctgcctgcaa gtcttgatcg
     9961 gttaaaccag gcttctctcc ctgattacgg ttaactagat aaatccgagt cgtactagta
    10021 aactcaggtt tgataacaaa agtactgtag gcaaaagcaa ctgaagaagt tataattgcc
    10081 actaataaaa tgaccaactt tcttttccat aaagctctga atagttgcaa tacatcgatt
    10141 tccaaagtgt tttgttcctt catattttct cctaaattaa ttgatccatt ataatttttc
    10201 tgggattatc tacaaaaagt tctttcgctt ttttcgctcc atatttctta gcaatgatat
    10261 catatgcctg ttgcatatat ggaggtctac tgtctaaatt gtgcatgtca cttgcaacta
    10321 catgaactaa atcacgttcc aaaaaatacc gagctctctt tttcatgaat ttatattttt
    10381 caccaaagaa cttaggtttt gaaacatgat aactatttat ctgagtatag caccccatat
    10441 caatcagttc acgaacacgt ttttcgttat tctctaaagc atcataacgt tcaatatgag
    10501 caattactgg cgtgattccc aacatcaaaa tattgctcaa tcccgtatga atctgacgat
    10561 aggaagtatg catgctaaac tcaatcaagg cataacgact atcattaagg gtaggaattt
    10621 cttttttttc tagcttttct agagcatcca gagtatagta tatctctgcg ccataagcaa
    10681 tgactaaatc atctgctact tcttttgcaa tttcccgaac ctgaagaaag ttttctgcta
    10741 tcttctcttc cggagtttca aacatgccct tgcgacggtg agaggtagag acaatggttc
    10801 tcaccccctg cctgtaggat tctgccaaga gagccttgct ttcctctctt gacttgggac
    10861 catcatctac atcaaagacg atgtgcgaat ggatgtctat cattttatct accctccatc
    10921 acatcctgta tagctgcttt aactacagtt aaactactat catctatttc catcacatag
    10981 aggttactgt ctggcattgc ataagaagga agatccatcc gacctgtccc ttttaaatct
    11041 tgagaattta ctttataatt ccctccactt tccaactgag tattcactaa atctatcata
    11101 gtctcaatcg gtatatttgt ttgaagagaa tcctgcaatc cttgaagaat actactatag
    11161 tttttcaaaa cctctgtaga agttaacttc tgaataattg ctacaatgac cttttgttgg
    11221 ttgcgaccac ggtcacggtc tccatcggtt agtgagtagc gttcacgtac aaaacctaaa
    11281 gcttgctcag agtctagatg gacattccct actgggaaat ggaacttccc atgtagagct
    11341 gaaaactctt gatcattatg aacatctacc cctcccaata agtcaatcat tttcaagaaa
    11401 gaagtgaagt tcaatcgcac atagtaattg atatccactc catagagatt ttctaaggtg
    11461 tgaatggacg aatcaactcc ataaatgccc gcatgggtta atttatcttt ttgattattt
    11521 ccactatctg cgattggtac ataggcatca cgtggcgttg tggtcaagag gattttcttg
    11581 gtatctcgat tgacagtcat taggatattg acatctgatc gcgacaccga actaatagga
    11641 ccataggtgt caattccact aacatagata ttgaaagact gattcttaga cgtcttagga
    11701 gcctctactt ttttagtgaa tcccttggta taaatctttt ttatcttcga tgcgtagtct
    11761 ggatactctg actcgatgat attttcaaag acactattta ggacaatggc cttagtctcc
    11821 cctgcaatca aactcttgta agctgccaag taagacgaac tctggttgac cgtcaaatcg
    11881 gtattctgac ttgacttgat atcagctagt agtttttgaa tattttcatt atcagtccca
    11941 gtcggtgctg tcacactcgt cagttgcgta acattttcga tcttactatc tgctaaaaca
    12001 gcgacactga ttgaatattc tgagtaatta gaagtcgcat ttaaacgatt ggtcagtcca
    12061 acaaactgct gtactgcaaa gagcgacact gagctgacaa ggatagagaa cagcaacaga
    12121 aaaatagtaa acttttcagc ttttttatag ataatcaaga gtagccctac caaggcaact
    12181 agtaggacta acgcagttac cactaggtta agatatctaa aagcaaggat attgtactta
    12241 aagattaaga acaataaaaa acaaattaac aataaataaa tagtcagcaa aacgatatta
    12301 acacttcgct tcactttctg tgaacgtgat tttttaaaac gtctactcat gattaacacc
    12361 tataccttga acatcataca attatatcac ttttttacgg taatgtctac acctttattt
    12421 tcactatctg catctttaag tatcttagta gacttcccgc gaaccaaaaa tatagtaaaa
    12481 tgaaataaga ataggacaaa tcaatcagga cagtcaaatc gatttctaac aatgttttag
    12541 aatcagatgt gtactattct agtttcaata taa
//
LOCUS       DAVBDR010000057        12492 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.057, whole genome shotgun sequence.
ACCESSION   DAVBDR010000057 DAVBDR010000000
VERSION     DAVBDR010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12492)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12492)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12492
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.057"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            310..570
                     /locus_tag="VQ540_001723"
     CDS             310..570
                     /locus_tag="VQ540_001723"
                     /inference="COORDINATES: protein motif:HMM:NF012235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET2545491.1"
                     /translation="MSGGETKRVALAKIILKNPPLIFADELTASLDSTTSQGIMKLLL
                     GMKNKNRLIIIATHNPDIWNQADEVINLNQLLQSIYIFYILK"
     gene            complement(674..1144)
                     /locus_tag="VQ540_001724"
     CDS             complement(674..1144)
                     /locus_tag="VQ540_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001043003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HET2545492.1"
                     /translation="MNKSEHRHQLIRALITKNKIHTQAELQTLLAENDIQVTQATLSR
                     DIKNMNLSKVREEDSAYYVLNNGSISKWEKRLELYMEDALVWMRPVQHQVLLKTLPGL
                     AQSFGSIIDTLSFPDAIATLCGNDVCLIICEDADTAQKCFEELKKFAPPFFFEE"
     gene            complement(1161..3434)
                     /locus_tag="VQ540_001725"
     CDS             complement(1161..3434)
                     /locus_tag="VQ540_001725"
                     /EC_number="3.4.14.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Xaa-Pro dipeptidyl-peptidase"
                     /protein_id="HET2545493.1"
                     /translation="MRFNQYSYINFPKENVLSELKKCGFDLQNTANHKDSLETFLRRF
                     FFTYQDTNYPLSILAADKKTDLLTFFQSEDELTADIFYTVAFQLLGFSYLVDFEDSDV
                     FRKETGFPIIYGDLIENLYQLLNTRTKKGNTLIDQLVSDGLIPEDNDYHYFNGKSLAT
                     FSNQDVIREVVYVESRVDTDQKGLSDLVKVSIIRPRFDGKIPAIMTASPYHQGTNDKA
                     SDKALYKMEGELEVKLPHKIELEKPQLNLVQPQGKAELIAEAEEKLTHINSSYTLNDY
                     FLPRGFANLYVSGVGTKDSTGFMTNGDYQQIEAYKNVIDWLNGRCRAFTDHTRQRQVK
                     ADWSNGKVATTGLSYLGTMSNGLATTGVDGLEVIIAEAGISSWYNYYRENGLVTSPGG
                     YPGEDFDSLAELTYSRNLLASDYIRGNEAHQADLEKVKAQLDRKTGDYNQFWHDRNYL
                     LNAHKVKAEVVFTHGSQDWNVKPLHVYQMFHALPTHIHKHLFFHNGAHVYMNNWQSID
                     FRESINALLTKKLLGQETDFQLPTVIWQDNTAPQTWLSLDNFGGQENCETFSLGQEEQ
                     AIQNQYPDKDFERYGKTYQTFNTELYQGKANQITINLPVTKDLHLNGRAQLNLRIKSS
                     TNKGLLSAQLLEFGQKKYLQPYPAILSARTIDNGRYHMLENLCELPFRPEAQRVVTKG
                     YLNLQNRNDLLLVEDITADEWMDVQFELQPTIYKLKEGDTLRLVLYTTDFEITIRDNT
                     DYHLTVDLAQSMLTLPC"
     gene            3781..6882
                     /locus_tag="VQ540_001726"
     CDS             3781..6882
                     /locus_tag="VQ540_001726"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000561528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HET2545494.1"
                     /translation="MIAQLDTKTVYSFMESVISIEKYVRAAKEYGYTHLAMMDIDNLY
                     GAFDFLEITKKYGIHPLLGLEMTVFVDDQGVNLRFLALSSVGYQQLMKLSTAKMQGEK
                     TWSVLSQYLEDIAVIVPYFDRVESLELGCDYYIGVYPETLASEFHHPILPLYRVNAFE
                     SRDREVLQVLTAIKENLPLREVPLRSRQDVFISASSLEKLFQERFPQALDNLEKLISG
                     ISYDLDTSLKLPRFNPARPAVEELRERAELGLVQKGLTSKEYQDRLDQELSVIHDMGF
                     DDYFLVVWDLLRFGRSNGYYMGMGRGSAVGSLVSYALDITGIDPVEKNLIFERFLNRE
                     RYTMPDIDIDIPDIYRPDFIRYVGNKYGSKHAAQIVTFSTFGAKQALRDVLKRFGVPE
                     YELSAITKKISFRDNLKSAYEGNLQFRQQINSKLEYQKAFEIACKIEGYPRQTSVHAA
                     GVVISDQDLTNYIPLKYGDEIPLTQYDAHGVEASGLLKMDFLGLRNLTFVQKMQELLA
                     ETEGIHLKIEEIDLEDKETLALFASGNTKGIFQFEQPGAIRLLKRVQPVCFEDVVATT
                     SLNRPGASDYINNFVARKHGQEEVTVLDPVLEDILAPTYGIMLYQEQVMQVAQRLAGF
                     SLGKADILRRAMGKKDASAMHEMRASFIQGSLEAGHTVEKAEQVFDVMEKFAGYGFNR
                     SHAYAYSALAFQLAYFKTHYPAIFYQVMLNSSNSDYLIDALEAGFEVASLSINTIPYH
                     DKIANKAIYLGLKSIKGVSNDLALWIIENRPYSNIEDFIAKLPENYLKLPLLEPLVKV
                     GLFDSFEKNRQKVFNNLANLFEFVKELGSLFGDAIYSWQESEDWTEQEKFYMEQELLG
                     IGVSKHPLQAIASKAIYPITPIGNLSENSYAIILVEVQKIKVIRTKKGENMAFLQADD
                     SKKKLDVTLFSDLYRQVGQEVREGAFYYIKGKVQSRDGRLQMIAQEIREAVAERFWIQ
                     VKNHESDQEISRILEQFKGPIPVIIRYEEEQKTIVSPHHFVAKSDELEAKLNEIVMKT
                     IYR"
     gene            6964..7971
                     /gene="pfkA"
                     /locus_tag="VQ540_001727"
     CDS             6964..7971
                     /gene="pfkA"
                     /locus_tag="VQ540_001727"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HET2545495.1"
                     /translation="MKRIAVLTSGGDAPGMNAAIRAVVRQAISEGMEVFGIYDGYAGM
                     VAGEIHPLDAASVGDIISRGGTFLHSARYPEFAQLEGQLKGIEQLKKHGIEGVVVIGG
                     DGSYHGAMRLTEHGFPAIGLPGTIDNDIVGTDFTIGFDTAVTTAMDAIDKIRDTSSSH
                     RRTFVIEVMGRNAGDIALWAGIATGADEIIIPEAGFKMEDIVASIKAGYECGKKHNII
                     VLAEGVMSAAEFGQKLKEAGDTSDLRVTELGHIQRGGSPTARDRVLASRMGAHAVKLL
                     KEGIGGVAVGIRNEKMVENPILGTAEEGALFSLTAEGKIVVNNPHKADIELSSLNKSL
                     S"
     gene            8028..9533
                     /gene="pyk"
                     /locus_tag="VQ540_001728"
     CDS             8028..9533
                     /gene="pyk"
                     /locus_tag="VQ540_001728"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HET2545496.1"
                     /translation="MNKRVKIVATLGPAVEIRGGKKFGEDGYWGEKLDVEASAKNIAK
                     LIEAGANTFRFNFSHGDHQEQGERMATVKLAEKIAGKKVGFLLDTKGPEIRTELFEGE
                     AKEYSYKTGEKIRVATKQGIKSTREVIALNVAGALDIYDDVEVGRQVLVDDGKLGLRV
                     VAKDDATREFEVEVENDGIIAKQKGVNIPNTKIPFPALAERDNDDIRFGLEQGINFIA
                     ISFVRTAKDVNEVRAICEETGNGHVQLFAKIENQQGIDNLDEIIEAADGIMIARGDMG
                     IEVPFEMVPVYQKMIIKKVNAAGKVVITATNMLETMTEKPRATRSEVSDVFNAVIDGT
                     DATMLSGESANGKYPLESVTTMATIDKNAQALLNEYGRLDSDSFERNSKTEVMASAVK
                     DATSSMDIKLVVTLTKTGHTARLISKYRPNADILALTFDELTERGLMLNWGVIPMLTD
                     APSSTDDMFEIAERKAVEAGLVESGDDIVIVAGVPVGEAVRTNTMRIRTVR"
     gene            complement(10265..10490)
                     /locus_tag="VQ540_001729"
                     /pseudo
     CDS             complement(10265..10490)
                     /locus_tag="VQ540_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838792.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            11338..12210
                     /locus_tag="VQ540_001730"
     CDS             11338..12210
                     /locus_tag="VQ540_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4300 family protein"
                     /protein_id="HET2545497.1"
                     /translation="MKKSRKLATLGICSALFLGLAACQQQHATSEGTNQRQSSSAKVP
                     WKASYTNLNNQVSTEEVKSLLSAHLDPNSVDAFFNLVNDYNTIVGSTGLSGDFTSFTH
                     TEYDVEKISHLWNQKKGDFVGTNCRINSYCLLKNSVTIPKLEKNDQLLFLDNDAIDKG
                     KVFDSQDKEEFDILFSRVPTEATTDVKVHAEKMETFFSQFQFNEKARMLSVVLHDNLD
                     GEYLFVGHVGVLVPADDGFLFVEKLTFEEPYQAIKFASKEDCYKYLGTKYADYTGEGL
                     AKPFIMDNDKWVKL"
     gene            12223..12387
                     /locus_tag="VQ540_001731"
     CDS             12223..12387
                     /locus_tag="VQ540_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001836122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2545498.1"
                     /translation="MTVILGFLFLFLMTWWVISIVNSQKPRKNETFIGYIQRYDIDGN
                     GYQSLPCPQN"
     gene            complement(12356..12492)
                     /locus_tag="VQ540_001732"
                     /pseudo
     CDS             complement(12356..12492)
                     /locus_tag="VQ540_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
BASE COUNT         3811 a         2175 c         2667 g         3839 t
ORIGIN      
        1 ctttctaatg agttgttttg tcgcttttca ttataggtca tatgggactt tttttctaca
       61 ataaaatagg ctccataata tctatagtgg atttacccac tacaaatatt atagaaccct
      121 tttttattga cagtatcagg atatcttttt caaatttttg gtttgttaga taatgaaaat
      181 gtttctatca atctagattt aggattaata aatcgtaaat gtaattataa agaaaaagat
      241 aagttaaaaa aagatgtatt agcaagagtt ggtctaactc atattcatct ataacaaaag
      301 atatatgaat tgtctggcgg tgaaacaaaa cgtgttgctt tagcgaaaat cattcttaaa
      361 aatccaccat taatattcgc ggatgagttg actgcatcac tcgattcgac gacttcacaa
      421 ggaattatga aattgttatt aggtatgaaa aataaaaatc gtctaatcat cattgcaact
      481 cataatcccg atatttggaa tcaagcagat gaagttataa atttaaatca attattacag
      541 tcaatatata tcttctatat tttaaagtaa ttttatctga atccgttaag agactattgt
      601 cccaggctct ttctgatgtt aaagactttc taccaggttt tttaaaagca taattgttag
      661 ttgtagtcat ttattattct tcaaagaaaa atggtggggc gaattttttc agttcttcaa
      721 agcacttttg agcagtatct gcatcttcac agatgataag acagacatca ttaccacaaa
      781 gggtagcgat agcgtcaggg aagctcaaag tatcaatgat agaaccaaag gattgagcca
      841 gtccaggaag ggtttttagt aggacttggt gttgaactgg gcgcatccag acaagggcgt
      901 cttccatgta gagttcgaga cgtttttccc attttgagat ggaaccattg ttaagaacat
      961 aataagcgct atcttcttcg cggacttttg ataggttcat atttttgatg tcgcgtgaga
     1021 gggttgcctg agttacttga atgtcgttct cagcaagaag ggtttgcaac tcagcctgtg
     1081 tatgaatctt gttttttgtg ataagagcgc gtataagttg gtggcggtgt tctgatttat
     1141 tcataataat gtaactcctt ttagcaaggt aaggtaagca tggactgagc gaggtcgaca
     1201 gtcaagtggt agtctgtatt gtcacggatg gtgatttcaa agtcagtagt atagaggact
     1261 aaacggagag tgtctccttc ttttagcttg taaatagttg gctgcagttc aaattgaacg
     1321 tccatccatt catctgcagt aatatcctct actaacagta aatcatttct attttgtaaa
     1381 ttaaggtaac cttttgtcac gactctttgt gcctctggtc taaatggcaa ttcacagaga
     1441 ttttccaaca tgtgatagcg accgttgtca atggttctag cacttaaaat agctggataa
     1501 ggttgtaggt atttcttttg cccaaattct agcagttggg cagataagag ccccttgttt
     1561 gtactggatt tgatacgaag attgagctga gcgcgaccgt ttaggtggag atctttagtc
     1621 acaggaaggt taatagtaat ctgattagct ttcccttgat agagctctgt attgaaggtt
     1681 tggtatgtct taccatagcg ctcaaaatcc ttatctgggt actggttttg aatagcttgc
     1741 tcttcttgac caagtgagaa ggtttcacag ttttcttgcc caccgaagtt atcaagtgat
     1801 aaccaagtct gtggagctgt attgtcctgc cagataacag taggaagttg aaagtctgtt
     1861 tcctgtccta gtaatttctt ggtcaataag gcatttatgg actcacggaa gtcaattgat
     1921 tgccaattgt tcatgtaaac atgggcacca ttatggaaaa agagatgctt gtgtatatga
     1981 gtaggaagag catggaacat ctggtaaaca tgaagtggtt tgacattcca atcctgagaa
     2041 ccatgagtaa agacaacctc tgcctttact ttatgggcat tgagcagata attgcggtca
     2101 tgccaaaact gattgtagtc cccagttttt cggtctagtt gagctttcac tttttctaag
     2161 tcagcttggt gagcttcatt gccacggata tagtcgctag ccaagagatt acgagaatag
     2221 gttaactcag caagggagtc aaagtcctca cctggataac cacctgggct agtcaccaga
     2281 ccgttttcac ggtagtagtt gtaccatgat gaaattcctg cctcggcaat gataacttct
     2341 aaaccatcga ctcctgtagt cgcaagacca ttggacatgg tacctagata ggaaagtccc
     2401 gttgtagcaa cttttccgtt tgaccaatca gccttgactt gacgctggcg cgtgtgatca
     2461 gtaaaggcac ggcaacggcc gttaagccaa tcgatgacat ttttataagc ctcgatttgc
     2521 tggtagtctc cattagtcat gaaacctgtc gagtctttgg taccaacacc tgagacatag
     2581 agattggcaa agcctctcgg aaggaagtag tcgtttagtg tatagctaga gttgatgtga
     2641 gttagctttt cctcagcctc tgctataagc tcagctttac cttggggttg gacgagattt
     2701 agttgaggtt tctctagctc aatcttgtga ggaagtttaa cctcaagctc gccctccatc
     2761 ttgtagagag ccttgtcact agccttgtca ttggttccct gatgataagg gctggctgtc
     2821 atgatggcag ggatttttcc atcaaaacga gggcgaataa tgctaacctt tactaggtct
     2881 gatagccctt tttggtcagt atcgacacga gactcaacgt aaacgacttc acgaatgaca
     2941 tcctggttag aaaaagtagc caaactcttg ccgttaaagt agtggtagtc attatcctcc
     3001 ggaataagac catcactaac aagttggtcg ataagagtat ttcctttttt ggtgcgagta
     3061 ttgagtaact gatagagatt ttcaatcaag tcaccatata taatgggaaa tccagtttct
     3121 ttacgaaaaa cgtcactatc ttcgaagtca accaaataag aaaagcctaa aagttgaaaa
     3181 gcaacagtat aaaaaatatc tgctgtcagt tcatcttctg attgaaaaaa tgtcagcagg
     3241 tctgtttttt tatcagctgc taggatagaa agtgggtagt tggtgtcttg ataagtgaaa
     3301 aagaaacgac gtaaaaaggt ttcaagtgag tctttgtgat tggctgtatt ttgtaaatca
     3361 aagccacatt tttttagttc agataagaca ttttcttttg gaaaattgat ataactatat
     3421 tgattaaaac gcatagaacc tccatataga atgacagtta aggttattat atcaaaaaaa
     3481 aagcagaaag ggaattgtta acttcaaaag gaaataatcc aataaaaatg aataaagtac
     3541 taaattcaat atagagaaca gagtaacaat aagaataaat agatagggta taaaagttct
     3601 aggagattta tattatatgc tttctgtttt tatatacaat atagtataaa tataaaaatg
     3661 atgacaaaaa tacaaatgaa tagaaaataa attagtaagc tgatgaaatt tttctcaaga
     3721 gaagccattt ataggtgaaa atggtataat atagtgagaa ggatagagga gaagtgtaaa
     3781 ttgatcgcac aactagatac aaaaacagtc tatagtttta tggaaagcgt catttcgatc
     3841 gaaaagtatg tgagagcagc taaagaatac ggctacactc atttggctat gatggatatt
     3901 gacaatcttt atggcgcttt cgactttcta gagattacaa aaaaatacgg cattcatcct
     3961 ttgctagggc ttgaaatgac agtgtttgta gatgatcagg gagtgaattt gcgcttttta
     4021 gctctatcta gtgtgggcta tcagcagttg atgaagcttt cgacagccaa gatgcagggg
     4081 gagaaaactt ggtcagtcct gtcccagtac ctggaggata tcgcggtcat tgtgccttat
     4141 tttgatagag ttgagtcgtt agaactaggc tgtgattact atataggggt ttatccagaa
     4201 acactagcaa gcgaatttca tcatcctatc ttacctcttt atcgggtcaa cgcttttgaa
     4261 agcagggata gagaagttct tcaagtttta acagcgatta aagaaaatct accgctcaga
     4321 gaagttccct tgcgttcgag acaagatgtc tttatatcag caagttcttt agagaaacta
     4381 ttccaagagc gttttccgca agctttggac aatttagaaa agcttatttc aggcatttct
     4441 tacgacttgg atactagtct gaaactgcct cgttttaatc cagctagacc agcagtagag
     4501 gagttgagag agcgtgctga actggggctt gttcagaagg ggttgactag taaagaatat
     4561 caagatagac tagaccaaga attgtctgtt attcatgata tgggctttga tgattatttc
     4621 ttggttgttt gggatttgtt gcgttttgga cgatcgaatg gctattatat gggaatggga
     4681 aggggttctg cagtaggcag tttggtttct tatgccttag acatcacggg gattgaccca
     4741 gtagagaaaa atctgatttt tgaacgcttt cttaatcgtg aacgctatac catgcctgat
     4801 attgatattg atatcccaga tatttatcgt ccagatttta tcagatatgt tggtaataaa
     4861 tatggtagta aacatgcggc acaaatcgtt actttttcaa cctttggagc caagcaagct
     4921 cttcgagatg tcttgaaacg ctttggtgtg ccagagtatg aattatctgc aattactaag
     4981 aaaatcagtt ttcgtgacaa tcttaagtcg gcctatgagg gcaatctcca gtttcgtcag
     5041 caaatcaata gtaagttaga ataccaaaaa gcttttgaga ttgcttgcaa gatagagggc
     5101 tatccaaggc aaacctctgt ccatgcggct ggtgttgtaa ttagtgacca agatttaacc
     5161 aactacattc ctctaaagta tggtgatgaa attccactga ctcagtatga tgctcatgga
     5221 gttgaggcta gcggactttt gaagatggac tttctgggac tacgaaattt gacctttgtc
     5281 cagaagatgc aagagttgct tgctgaaaca gaaggtattc atctgaaaat tgaagaaatc
     5341 gatttagaag acaaagaaac attagcttta tttgcctctg gtaatacaaa aggtatcttt
     5401 caatttgagc aaccaggtgc cattcgtctg cttaagcgtg tgcaaccagt ctgttttgaa
     5461 gatgtcgtcg cgactacttc tctaaatcga ccgggtgcta gtgactatat caataatttt
     5521 gtggcaagaa agcatgggca ggaagaagtg actgttctgg atccagtact ggaggatatt
     5581 ttggctccaa cctacggcat aatgctctat caggagcagg ttatgcaggt tgcccagcga
     5641 cttgccggat ttagtcttgg gaaagccgat attttgcgtc gggctatggg gaaaaaggat
     5701 gcctctgcca tgcatgagat gagggcttcc tttattcaag gttcattaga agctggtcat
     5761 actgtggaaa aagcagagca ggtctttgat gttatggaga agtttgcagg ttatggtttt
     5821 aacaggtcac acgcctatgc ctactcagcc ttggccttcc agttggctta tttcaaaacg
     5881 cattatccag ccatttttta tcaggtcatg ttaaattctt ccaacagtga ttacttaata
     5941 gatgcacttg aagcaggttt tgaagtagcc tctctatcca tcaacaccat tccctatcac
     6001 gataaaattg ccaacaaggc catctatcta ggtttgaaat ccattaaagg agtcagtaat
     6061 gatttagctc tctggattat tgaaaataga ccttattcta acattgaaga ttttatagct
     6121 aaattacctg agaattatct gaaacttcct ctgctagaac ctttggtaaa agttggtctt
     6181 ttcgattcat ttgaaaaaaa tcgtcaaaaa gtatttaata acttagctaa tctatttgaa
     6241 tttgtgaaag agttgggaag tttgtttgga gatgctattt atagttggca ggaatcggaa
     6301 gattggacgg aacaagaaaa attttatatg gaacaagagc ttttagggat aggtgtcagc
     6361 aaacatccac tacaagctat tgcaagtaag gctatttacc cgattacccc aatcggaaat
     6421 ttgtcagaaa atagctatgc tattatcttg gttgaagttc agaaaataaa agtgattcgt
     6481 accaaaaagg gtgaaaatat ggccttctta caggcagatg atagtaagaa aaaattggat
     6541 gttacactct tctcagattt atatcgacag gttggtcagg aagtaagaga aggagcattc
     6601 tactatatca aagggaaagt ccaatcacgt gacggtcgtc tgcaaatgat tgcacaagaa
     6661 ataagagaag cagttgctga acgcttttgg atacaggtga aaaatcatga atcggatcaa
     6721 gaaatttcac gtattttaga acaatttaaa ggcccaatcc cagtcatcat ccggtatgaa
     6781 gaggaacaga aaaccatcgt ttctccccat cattttgtag ctaaatctga tgaattagag
     6841 gcgaaattga atgaaatcgt tatgaaaacg atttatcgct aaaaatacgg aaaatagaag
     6901 aattttaaaa tcaaatgtga tataatcaag aagaatgtta aaagaaaaag gagcataacc
     6961 aatatgaaac gtattgctgt tttgactagt ggtggagacg cccctggtat gaacgctgcc
     7021 atccgtgcag ttgttcgtca agcaatttca gaaggaatgg aagtgtttgg tatctatgac
     7081 ggatatgctg gtatggttgc cggtgaaatt catcccctag atgcagcttc agtaggggac
     7141 atcatttctc gtggtggtac tttccttcac tcagctcgtt acccagagtt cgctcaactt
     7201 gaagggcaac ttaaagggat tgagcaattg aaaaaacacg gaattgaagg tgtagttgtt
     7261 atcggtggtg acggatctta ccacggcgct atgcgtttga ctgaacatgg cttcccagct
     7321 attggtcttc caggtacaat cgataacgat atcgttggta ctgactttac aatcggtttt
     7381 gacacagcgg ttactactgc catggacgct atcgataaga ttcgtgatac atcatcaagt
     7441 caccgtcgta cttttgtaat cgaagttatg ggacgtaacg ctggtgatat cgctctttgg
     7501 gctggtattg caactggtgc tgatgaaatc atcatccctg aagcaggctt caagatggaa
     7561 gatatcgtag caagcatcaa agctggttat gaatgtggta aaaaacacaa tatcatcgtc
     7621 ttagctgaag gtgtgatgtc agcggctgaa tttggtcaaa aacttaaaga agctggagat
     7681 acaagcgacc ttcgtgtaac agaacttgga catattcaac gtggtggttc tccaactgcg
     7741 cgtgaccgtg ttttggcgtc acgtatgggt gcacatgctg ttaaacttct taaagaaggt
     7801 atcggtggtg ttgcggttgg tattcgtaac gaaaaaatgg ttgaaaatcc aattcttggt
     7861 actgcagaag aaggggcatt gtttagcctt actgcagaag gtaagattgt ggttaacaac
     7921 ccgcacaaag ccgatattga gctatctagc ttgaataaga gcttgtcata atttacaatt
     7981 tagttaataa gaccaaaaag gtcatatata aaggagtcac aaaaatcatg aacaaacgtg
     8041 taaagatcgt tgcaactttg ggtcctgcgg tagaaatccg tggtggtaaa aaattcggtg
     8101 aggacggata ctggggtgaa aaacttgatg ttgaagcttc agctaaaaac attgctaaat
     8161 tgattgaagc tggtgctaac acattccgat tcaacttctc acacggcgac caccaagaac
     8221 aaggtgagcg tatggcaact gttaaacttg cggaaaaaat tgcaggtaaa aaagttggtt
     8281 tccttcttga tacaaaagga cctgaaatcc gtacagaatt gttcgaaggt gaagctaaag
     8341 aatattcata caaaactggt gaaaaaattc gtgttgcaac taaacaagga atcaaatcaa
     8401 ctcgtgaagt gattgcgttg aacgttgctg gtgctcttga tatctatgat gatgttgaag
     8461 ttggtcgtca agttttggtt gacgatggta aacttggtct tcgtgtggtt gctaaagatg
     8521 atgcaactcg tgaatttgaa gttgaagttg aaaacgatgg tatcatcgct aaacaaaaag
     8581 gtgtgaacat ccctaacact aaaattcctt tcccagctct tgctgaacgc gataacgacg
     8641 atatccgttt cggtcttgaa caaggtatca acttcatcgc aatttcattc gtacgtactg
     8701 caaaagatgt gaacgaagtt cgtgcaatct gtgaagaaac tggaaacgga catgttcaat
     8761 tattcgctaa aatcgaaaac caacaaggta tcgataactt agacgaaatc atcgaagcag
     8821 ctgatggtat tatgattgct cgtggtgata tgggtatcga agtaccgttc gaaatggttc
     8881 cagtttatca aaaaatgatt atcaagaaag tcaatgctgc aggtaaagtt gttatcactg
     8941 caacaaacat gcttgaaaca atgactgaaa aaccacgtgc aactcgttca gaagtatcag
     9001 acgtattcaa cgctgttatc gacggaactg acgctacaat gctgtcaggc gagtctgcaa
     9061 acggtaaata cccactcgag tcagtaacta caatggctac aatcgacaag aatgctcaag
     9121 ctcttcttaa tgaatacgga cgtcttgatt cagattcatt tgagcgtaac tctaagacag
     9181 aagtaatggc ttctgctgtt aaagatgcta ctagctcaat ggatatcaaa ttggtcgtaa
     9241 ctcttactaa gacaggtcat actgcacgtt tgatttctaa ataccgtcca aatgctgaca
     9301 tcttagcatt gacatttgac gaattgacag aacgtggctt gatgttgaac tggggtgtta
     9361 tcccaatgtt gacagatgct ccatcttcaa ctgacgatat gttcgaaatc gctgaacgta
     9421 aagcggtaga agcaggtctc gttgagtcag gcgatgatat cgttatcgtt gctggtgtgc
     9481 cagtaggaga agctgttcgc acaaacacaa tgcgtatccg cacagtacgt taagaaaaat
     9541 ataaaaacct atcatatcca gctttagagc ttgtgtgata ggctttttgt atagagggta
     9601 agaaataggc aaaactttca taatggattg atactcttcg aaaatcaaat tcaaaccacg
     9661 tcagcgtcgc cttaccgtat atatgttact gacttcgtca gttctatcta caacctcaaa
     9721 gcagtgcttt gagcaacctg cggctagctt cctagtttgc tctttgattt tcattgagta
     9781 tgaaataaga tatgcacaaa ttgattagga aattcaaatg aatttctaca aatgttttag
     9841 caatcgtaat gtacttgtct agattcgatc tgatatattt tcgatttaat gatatggtat
     9901 ttaaaacctc caaagtagct tgctccattc ttttacttac gtgagtgtag atgttattta
     9961 ctgttttagc gtttttgtgt tccactctaa ccattatagc attcttctca gctagtgtac
    10021 taaggagtgt gtgcctgaaa atatgggaac taaggggctg gtttatcggt ttctctagtt
    10081 tagtatttgc cttttgcaaa gtgatgttaa atgcctttct ctaaatttac atatcactat
    10141 tgtttaacaa aatctaatct actttaggtc acttattctt tttttgaaat gtagaatgaa
    10201 ctttttcaaa gtttttcgaa tcttttaaaa tctgtttgtt ttatatcgcc attctccccc
    10261 ttttttaatt ctccctatat agcctgacaa ctttcccgat ggtacgaata tggttgcttt
    10321 cgtctaggtg gatgtcgggg tatttgggat tgagtttttt taaggtagcc ttggcggagt
    10381 ttcttgacat agttagcgcc gtctacttgg aagatgccga tggtattata gtcaatctgt
    10441 ggggtattct tgataaatag gtagtcgctg tttcttatct ttggctccat ggacttgctg
    10501 acgacataag cgattgggtc gtagtcgtct gggataatgg aaactccata actaaatcgt
    10561 cgtcctgcat cgagcggcta cctgcagaga taaactacct aacacgagag taagtagtct
    10621 gtctgtagtc gtccagtctg atgattttta cgatatttcg tttttctgct catacagttg
    10681 cctctcggca taggtcagaa ctttaccttg tctgggtggt gcccgttggt cgtagataga
    10741 ttggatatcg ctaggagaat ccttttgaac tggaggaaag agggtatcaa tcaagctact
    10801 gaatacttta gctaagtcaa atatagtatt tttcttagta gacctaaccc ttttttcata
    10861 atttccaatg gtgtttttac ttataccaat cttagtaccc aattcttatt gagtccaacc
    10921 attactagtc tatattgttt tatagttgat tgagtttgga atagtacgct gtagctgcta
    10981 aaacatttct aggaattaat ttgactttcc taatagagtt gttcatatct tatttcaatc
    11041 tactatgttt ttcacctcta acaatcgcaa tctcttcttt atccatgaat gaaatcgctt
    11101 tctatttttg taagtaaagc atcacacgaa atccacgaaa atgaaaacct ttgttgtgtt
    11161 ttcgtaaaaa atttgttgac agagcacgaa acgcctacta taattaaatc aagcttaagg
    11221 aaataacaaa aaaacaaatc ggagggaaag acgatgaaca cattaaatga gaaagtaatc
    11281 aatatctgta aagcagtagt taaagaaact ttaatccaag acatttagga gaaagaaatg
    11341 aagaaatcaa gaaaattagc cacattagga atctgttcag ccttgttttt aggcttggct
    11401 gcttgtcaac aacaacatgc tacttctgag gggacgaatc aaaggcaaag cagttcagcg
    11461 aaagttccat ggaaagcttc atacaccaac ctaaacaacc aggtaagtac agaagaggtc
    11521 aaatctctct tatcagctca cttggatcca aatagtgttg atgcattttt taatctcgtt
    11581 aatgactata ataccattgt cggctcaact ggcttatcag gagatttcac ttcctttact
    11641 cacaccgaat acgatgttga gaaaatcagt catctctgga atcaaaagaa gggcgatttc
    11701 gttgggacca actgccgtat caatagttat tgtcttttga aaaattcagt caccattcca
    11761 aagcttgaaa agaatgacca attgcttttc ctagataacg atgcgattga taaaggaaag
    11821 gtctttgatt cacaagataa ggaagagttt gatattctat tttcgagagt tccaactgag
    11881 gcaactacag atgtcaaggt tcacgctgaa aagatggaaa cattcttctc acaatttcaa
    11941 ttcaatgaaa aagctcgaat gctgtctgta gtcttgcacg acaatctgga tggcgagtat
    12001 ctgtttgtag gccatgttgg ggtcttagta cctgctgatg acggtttctt atttgtagag
    12061 aaattgactt tcgaagagcc ctaccaagcg attaaatttg ctagtaagga agattgctac
    12121 aagtatttgg gcaccaagta tgcggattat acaggcgagg gactggctaa gccttttatc
    12181 atggataatg ataagtgggt taaactttaa tagtgttatg atatgacagt aatcttagga
    12241 tttttatttc tatttttgat gacttggtgg gttatttcaa tcgttaatag ccagaaacca
    12301 cgcaaaaatg aaacatttat tggctatatc caaagatacg atattgatgg gaatggctat
    12361 caatcattac cgtgtcctca gaactgagag gagttcttga aaccgtaaaa ccgctttgaa
    12421 caagagttac ttcaacccat tggctccgac ggagtaagtt gctttcgtga ataccaaaat
    12481 cagccgcaat tt
//
LOCUS       DAVBDR010000058        11954 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.058, whole genome shotgun sequence.
ACCESSION   DAVBDR010000058 DAVBDR010000000
VERSION     DAVBDR010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11954)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11954)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11954
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.058"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            complement(101..1732)
                     /locus_tag="VQ540_001733"
     CDS             complement(101..1732)
                     /locus_tag="VQ540_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HET2545499.1"
                     /translation="MSINWQEILFHFLGGLGLFLYSIKTMGDGLQQAAGDRLRFYIDK
                     YTSNPFFGVLVGIGMTALIQSSSGVTVITVGLVSAGLLTLRQAIGIVMGANIGTTVTS
                     FLIGFKLGNYALPMLFIGAVCLFFTKNRTVNNIGRILFGVGGIFFALNLMSGAMAPLK
                     DLQVFKDYMIELSKNPVLGVFVGTGLTLLIQASSATIGILQNLYAGNLIDLQGALPVL
                     FGDNIGITITAIIASLGANIAAKRVAGAHVAFNVIGTVVCVIFLVPFTVLIHWFEATL
                     NLAPEMTIAFAHGTFNITNTIVQFPFIGALAYFVTKIIPGEDEVVKYEPLYLDEHFIK
                     QAPSIALGNAKKELLHLGNYAAKAFDLSYKYIIDLDEKVAEKGHKTEEAINTIDEQLT
                     RYLIALSSEALSQKESEVLTNILDSSRDLERIGDHTEALLNLTDYLQRKNVEFSDAAL
                     KELEEVYRQTSDFIKDALDSVENNDIEKARSLVERHEAINKIERVLRKTHIKRLNKGE
                     CSTQAGVNFIDIISHYTRVSDHAMNLAEKVFAEQI"
     gene            2025..7004
                     /locus_tag="VQ540_001734"
     CDS             2025..7004
                     /locus_tag="VQ540_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000795197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial Ig-like domain-containing protein"
                     /protein_id="HET2545500.1"
                     /translation="MKNPFFERRCRYSIRKLSVGACSLMIGAVLFAGPALAEETAVPE
                     NSGANTELVSGESEHSTNEADKQNEGEHARENKLEKAEGVAIASETASPASNEAATTE
                     TAEAASAAKPEEKASEVVAETPSAEAKPKSDKETEAKPEATNQGDESKPAAEANKTEK
                     EVQPDVPKNTEKTLKPKEIKFNSWEELLKWEPGAREDDAINRGSVVLASRRTGHLVNE
                     KASKEAKVQALSNTNSKAKDHASVGGEEFKAYAFDYWQYLDSMVFWEGLVPTPDVIDA
                     GHRNGVPVYGTLFFNWSNSIADQERFAEALKQDADGSFPIARKLVDMAKYYGYDGYFI
                     NQETTGDLVKPLGEKMRQFMLYSKEYAAKVNHPIKYSWYDAMTYNYGRYHQDGLGEYN
                     YQFMQPEGDKVPADNFFANFNWDKAKNDYTIATANWIGRNPYDVFAGLELQQGGSYKT
                     KVKWNDILDENGKLRLSLGLFAPDTITSLGKTGEDYHKNEDIFFTGYQGDPTGQKPGD
                     KDWYGIANLVADRTPAVGNTFTTSFNTGHGKKWFVDGKVSKDSEWNYRSVSGVLPTWR
                     WWQTSTGEKLRAEYDFTDAYNGGNSLKFSGDVAGKTDQDVRLYSTKLEVTEKTKLRVA
                     HKGGKGSKVYMAFSTTPDYKFDDADAWKELTLSDNWTNEEFDLSSLAGKTIYAVKLFF
                     EHEGAVKDYQFNLGQLTISDNHQEPQSPTSFSVVKQSLKNAQEAEAVVQFKGNKDADF
                     YEVYEKDGDSWKLLTGSSSTTIYLPKVSRSASAQGTTQELKVVAVGKNGVRSEAATTT
                     FDWGMTVKDTSLPKPLAENIVPGATVIDSTFPKTEGGEGIEGMLNGTITSLSDKWSSA
                     QLSGSVDIRLTKPRTVVRWVMDHAGAGGESVNDGLMNTKDFDLYYKDADGEWKLAKEV
                     RGNKAHVTDITLDKPITAQDWRLNVVTSDNGTPWKAIRIYNWKMYEKLDTESVNIPMA
                     KAAARSLGNNKVQVGFADVPAGATITVYDNPNSQTPLATLKSEVGGDLASAPLDLTNQ
                     SGLLYYRTQLPGKEISNVLAVSVPKDDRRIKSVSLETGPKKTSYAEGEDLDLRGGVLR
                     VQYEGGTEDELIRLTHAGVSVSGFDTHHKGEQNLTLQYLGQPVNANLSVTVTGQDEAS
                     PKTILGIEVSQEPKKDYLVGDSLDLSEGRFAVAYSNDTMEEHSFTDEGVEISGYDAQK
                     TGRQTLTLRYQGHEVNFDVLVSPKAALNDEYLKQKLAEVEAAKNKVVYNFASPEVKEA
                     FLKAIEAAEQVLKDHETSTQDQVNDRLNKLTEAHKALNGQEKFKEEKTELDRLTGEVQ
                     ELLAAKPNHPSGSALAPLLEKNKALVEKVDLSPEELATAKQSLKDLVALLKEDKPAVF
                     SDSKTGVEVHFSNKEKTVIKGLKVERVQASAEEKKYFAGEDAHVFEIEGLDEKGQDVD
                     LSYASIVKIPIEKDKKVKKVFFLPEGKEAVELAFEQTDSHVIFTAPHFTHYAFVYESA
                     EKPQPAKPAPQNKVLPKPTYQPASDQQKAPKLEVQEEKVAFHRQEHENAEMLVGEQRV
                     IIQGRDGLLRHVFEVDENGQRRLRSTEVIQEAIPEIVEIGTKVKTVPAVVATQEKPAQ
                     NTAVKSEEASKQLPNTGTADANEALIAVLASLGLASLALTLRRKREDKD"
     gene            7094..8290
                     /locus_tag="VQ540_001735"
     CDS             7094..8290
                     /locus_tag="VQ540_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HET2545501.1"
                     /translation="MAKLTVKDVDLKGKKVLVRVDFNVPLKDGVITNDNRITAALPTI
                     KYIIEQGGRAILFSHLGRVKEEADKAGKSLAPVAADLAAKLGQDVVFPGVTRGAELEA
                     AINALEDGQVLLVENTRYEDVDGKKESKNDPELGKYWASLGDGIFVNDAFGTAHRAHA
                     SNVGISANVEKAVAGFLLENEIAYIQEAVETPERPFVAILGGSKVSDKIGVIENLLEK
                     ADKVLIGGGMTYTFYKAQGIEIGNSLVEEDKLDVAKALLEKANGKLILPVDSKEANAF
                     AGYTEVRDTEGEAVSEGFLGLDIGPKSIAKFDEALTGAKTVVWNGPMGVFENPDFQAG
                     TIGVMDAIVKQPGVKSIIGGGDSAAAAINLGRADKFSWISTGGGASMELLEGKVLPGL
                     AALTEK"
     gene            8426..8953
                     /locus_tag="VQ540_001736"
     CDS             8426..8953
                     /locus_tag="VQ540_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HET2545502.1"
                     /translation="MSYFKKYKFDKSQFKLGMRTFKTGIAVFLVLLIFGFFGWKGLQI
                     GALTAVFSLRESFDESVHFGTSRILGNSIGGLYALVFFLLNTFFHEAFWVTLVVVPIC
                     TMLTIMTNVAMNNKAGVIGGVAAMLIITLSIPSGETILYVFVRVLETFMGVFVAIIVN
                     YDIDRIRLFLEKKEK"
     gene            9030..9386
                     /gene="glnR"
                     /locus_tag="VQ540_001737"
     CDS             9030..9386
                     /gene="glnR"
                     /locus_tag="VQ540_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000659547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor GlnR"
                     /protein_id="HET2545503.1"
                     /translation="MKEKEFRRNMAVFPIGSVMKLTDLSARQIRYYEDQELIKPDRNE
                     GNRRMYSLNDMDRLLEIKDYISEGYNIAAIKKKYAEREAKSKKAVSQTEVRRALHNEL
                     LQQGRFASVQSPFGRG"
     gene            9423..10769
                     /gene="glnA"
                     /locus_tag="VQ540_001738"
     CDS             9423..10769
                     /gene="glnA"
                     /locus_tag="VQ540_001738"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HET2545504.1"
                     /translation="MPITAADIRREVKEKNVTFIRLMFSDILGTMKNVEIPATDEQLD
                     KVLSNKVMFDGSSIEGFVRINESDMYLYPDLDTWTVFPWGDENGSVAGLICDVYTTEG
                     EPFAGDPRGNLKRALRHMEEVGFKSFNLGPEPEFFLFKLDENGDPTLEVNDKGGYFDL
                     APTDLADNTRREIVNVLTKMGFEVEASHHEVAVGQHEIDFKYDEVLRACDKIQIFKLV
                     VKTIARKHGLYATFMAKPKFGIAGSGMHCNMSLFDAEGNNAFFDPNDPKGMQLSETAY
                     HFLGGLIKHAYNYTAIMNPTVNSYKRLVPGYEAPVYIAWAGRNRSPLVRVPASRGMGT
                     RLELRSVDPMANPYIAMAVLLEVGLYGIENKIEAPAPIEENIYIMTAEERKEAGITDL
                     PSTLHNALKALTEDEVVKAALGDHIYTSFLEAKRIEWASYATFVSQWEIDNYLDLY"
     gene            complement(10865..10984)
                     /locus_tag="VQ540_001739"
     CDS             complement(10865..10984)
                     /locus_tag="VQ540_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine synthetase"
                     /protein_id="HET2545505.1"
                     /translation="MPDIVFEIEFFHSDSLIFFYTSDDKSNSQKSQEDFSKNK"
     gene            11242..11379
                     /locus_tag="VQ540_001740"
     CDS             11242..11379
                     /locus_tag="VQ540_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001067591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2545506.1"
                     /translation="MNPDRAEEYFCRGCQGENPEDIEFYDEQLQAEKVEALNIRLEVK
                     N"
     gene            11472..11954
                     /locus_tag="VQ540_001741"
                     /pseudo
     CDS             11472..11954
                     /locus_tag="VQ540_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187281.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
BASE COUNT         3840 a         2180 c         2568 g         3366 t
ORIGIN      
        1 tactatatat ctgcagaata ctctttcagt ttcattcagc ctagtcttgc ttaggaaaaa
       61 gtaaaaagcc atccaattat gatggatagc ttcttggttc ttagatttgt tctgcaaaaa
      121 ccttttcagc aaggttcata gcgtggtctg atacacgagt gtagtgtgag atgatgtcga
      181 taaagttgac cccagcttgt gttgaacatt cgcctttgtt gaggcgtttg atgtgggttt
      241 ttctgagaac acgttctatc ttattgattg cttcatgacg ttctacaaga ctgcgtgctt
      301 tttcaatatc attgttttcc acactatcca gagcatcttt gataaagtca ctagtttggc
      361 ggtaaacttc ctctaattct ttcaaggcgg catcagaaaa ttcaacattt ttccgttgaa
      421 gatagtcagt cagattgagt agagcctccg tgtggtctcc aatccgttcc aaatcacggg
      481 aggaatcaag gatattggta agcacttcac tttctttttg gctgagagct tcgcttgaaa
      541 gggcaatgag ataacgtgtt aattgctcat cgatggtgtt aattgcttct tcggttttat
      601 gccctttttc agcaactttt tcatccaagt caatgatgta cttataggaa aggtcaaagg
      661 ctttagcagc gtagtttcct aagtgcaaga gctctttctt agcatttcct agagcgatag
      721 atggggcctg tttgatgaaa tgttcatcaa gatataaggg ttcgtatttg acaacctcgt
      781 cctctccagg aataatcttg gttacaaagt aagccagagc tccgataaat ggaaattgga
      841 caatggtgtt ggtaatatta aaggttccgt gagcaaaggc gatggtcatt tccggtgcta
      901 gatttagcgt agcttcaaac caatgaatca ggacagtaaa aggaactaga aaaataacgc
      961 agacgactgt tccgataacg ttgaaggcaa catgagctcc tgctacccgt ttagctgcaa
     1021 tattagcccc taaagaggca atgatggctg taatggttat cccgatattg tcaccaaata
     1081 gaactggcaa agctccctgt aggtcaatta gattgccggc gtagaggttt tgtaaaatcc
     1141 caatggtagc cgaagaagct tgaattagca aggtcaagcc ggtaccgaca aagacaccca
     1201 aaacaggatt cttacttagc tcaatcatat agtccttaaa gacctgtaaa tccttgagtg
     1261 gagccattgc gccgctcatg agattgaggg caaaaaagat accaccgaca ccaaagagga
     1321 tgcgtccgat attattgact gtccgatttt ttgtaaaaaa gagacagacg gcaccgataa
     1381 agagcatagg tagggcatag ttacctaatt taaaaccgat gagaaaggat gtgacagttg
     1441 tcccaatatt agcacccatg acaatcccga tagcctgacg taaggttaag agaccggcac
     1501 tgaccaggcc gactgtgata actgttacac cagaactaga ctgaattaga gcagtcatcc
     1561 caataccaac cagaactcca aagaaaggat tactagtata tttgtcaatg taaaaacgaa
     1621 ggcgatctcc agcagcttgt tgcaaaccgt ctcccatggt cttgatgcta tataagaata
     1681 gccccagacc acctaaaaag tgaaataaaa tttcctgcca attaatggac atttcttttt
     1741 cctccgaaaa ataatcgcgg aatatcttct attctatttt aaaggataaa agtaaatcta
     1801 acaagtgtta atgtcaagtt tgtaaaagaa aattataatt gataagtgta ttatttttaa
     1861 gagtttttaa ccttatttta gatttgtgca aacagttatt gttttttgtc taaaaatgtt
     1921 ttaggataaa aatgtgatta tcatggttct agagtttgat aaaaaactac agaatataaa
     1981 gcgctttctt gaaaacaaca aaatcaatct tttaggagga gaaaatgaag aatccatttt
     2041 ttgaaagacg ttgtcgttac agtattcgta agttatcagt aggagcctgc tcgctgatga
     2101 ttggtgctgt tttatttgct ggtccagcct tggctgaaga aactgcagtt cctgaaaata
     2161 gcggagctaa tacagagctt gtttcaggag agagtgagca ttcgaccaat gaagctgata
     2221 agcagaatga aggggaacat gctagagaaa acaagctaga aaaggcagaa ggagtagcga
     2281 tagcatctga aactgcttcg ccagcaagca atgaagctgc aactactgaa actgcagaag
     2341 cagctagcgc agctaaacca gaggaaaaag caagtgaggt ggttgcagaa acaccatctg
     2401 cagaagcaaa acctaagtct gacaaggaaa cagaagcaaa gcccgaagca actaaccaag
     2461 gggatgagtc taaaccagca gcagaagcta ataagactga aaaagaagtc cagccagatg
     2521 tccctaaaaa tacagaaaaa acattaaaac caaaggaaat caaatttaat tcatgggaag
     2581 aattgttaaa atgggaacca ggtgctcgtg aagatgatgc tattaaccgc ggatctgttg
     2641 tcctcgcttc acgtcggaca ggtcatttag tcaatgaaaa agctagcaag gaagcaaaag
     2701 ttcaagcctt atcaaacacc aattctaaag caaaagacca tgcttctgtt ggtggagaag
     2761 agttcaaggc ctatgctttt gactattggc aatatctaga ttcaatggtc ttctgggaag
     2821 gtctcgtacc aactcctgac gttattgatg caggtcaccg taacggggtt cctgtatacg
     2881 gtacactctt cttcaactgg tctaatagta ttgcagatca agaaagattt gctgaagctt
     2941 tgaagcaaga cgcagatggt agcttcccaa ttgcccgtaa attggtagac atggccaagt
     3001 attatggcta tgatggctat ttcatcaacc aagaaacaac tggagatttg gttaaacctc
     3061 ttggagaaaa gatgcgccag tttatgctct atagcaagga atatgctgct aaggtaaacc
     3121 atccaatcaa gtattcttgg tacgatgcca tgacctataa ctatggacgt taccatcaag
     3181 atggtttggg agaatacaac taccaattca tgcaaccaga aggagataag gttccggcag
     3241 ataacttctt tgctaacttt aactgggata aggctaaaaa tgattacact attgcaactg
     3301 ccaactggat tggtcgtaat ccttatgatg tatttgcagg tttggaattg caacagggtg
     3361 gttcctacaa gacaaaggtt aagtggaatg acattttaga cgaaaatggg aaattgcgcc
     3421 tttctcttgg tttatttgcc ccagatacca ttacaagttt aggaaaaact ggtgaagatt
     3481 atcataaaaa tgaagatatc ttctttacag gttatcaagg agaccctact ggccaaaaac
     3541 caggtgacaa agattggtat ggtattgcta acctagttgc ggaccgtacg ccagcggtag
     3601 gtaatacttt tactacttct tttaatacag gtcatggtaa aaaatggttc gtagatggta
     3661 aggtttctaa ggattctgag tggaattatc gttcagtatc aggtgttctt ccaacatggc
     3721 gctggtggca gacttcaaca ggggaaaaac ttcgtgcaga atatgatttt acagatgcct
     3781 ataatggcgg aaattccctt aaattctctg gtgatgtagc cggtaagaca gatcaggatg
     3841 tgagacttta ttctactaag ttagaagtaa ctgagaagac caaacttcgt gttgcccaca
     3901 agggaggaaa aggttctaaa gtttatatgg cattctctac aactccagac tacaaattcg
     3961 atgatgcaga tgcatggaaa gagctaaccc tttctgacaa ctggacaaat gaagaatttg
     4021 atctcagctc actagcaggt aaaaccatct atgcagtcaa actatttttc gagcatgaag
     4081 gtgctgtaaa agattatcag ttcaacctcg gacaattaac tatctcggac aatcaccaag
     4141 agccacaatc gccgacaagc ttttctgtag tgaaacaatc tcttaaaaat gcccaagaag
     4201 cggaagcagt tgtgcaattt aaaggcaaca aggatgcaga tttctatgaa gtttatgaaa
     4261 aagatggaga cagctggaaa ttactaactg gctcatcttc tacaactatt tatctaccaa
     4321 aagttagccg ctcagcaagt gctcagggta caactcaaga actgaaggtt gtagcagtcg
     4381 gtaaaaatgg agttcgttca gaagctgcaa ccacaacctt tgattggggt atgactgtaa
     4441 aagataccag cctaccaaaa ccactagctg aaaatatcgt tccaggtgca acagttattg
     4501 atagtacttt ccctaagact gaaggtggag aaggtattga aggtatgttg aacggtacca
     4561 ttactagctt gtcagataaa tggtcttcag ctcagttgag tggtagtgtg gatattcgtt
     4621 tgaccaagcc acgtaccgtt gttagatggg tcatggatca tgcaggagct ggtggtgagt
     4681 ctgttaacga tggcttgatg aacactaaag actttgacct ttattataaa gatgcagatg
     4741 gtgagtggaa gctagctaag gaagtccgtg gtaacaaagc acacgtgaca gatatcactc
     4801 ttgataaacc aatcactgct caagactggc gcttgaatgt tgtcacttct gacaatggaa
     4861 ctccatggaa ggctattcgt atctataact ggaaaatgta tgaaaagctt gatactgaga
     4921 gtgtcaatat tccgatggcc aaggctgcag cccgttctct aggcaataac aaggtacaag
     4981 ttggctttgc agatgtaccg gctggagcaa ctattaccgt ttatgataat ccaaattctc
     5041 aaactccgct cgcaaccttg aagagcgaag ttggaggaga cctagcaagt gcaccattgg
     5101 atttgacaaa tcaatctggt cttctttatt atcgtaccca gttgccaggc aaggaaatta
     5161 gtaatgtcct agcagtttcc gttccaaaag atgacagaag aatcaagtca gtcagcctag
     5221 aaacaggacc taagaaaaca agctacgccg aaggggagga tttggacctt agaggtggtg
     5281 ttcttcgagt tcagtatgaa ggaggaactg aggacgaact cattcgccta actcacgcag
     5341 gtgtatcagt atcaggtttt gatacgcatc ataagggaga acagaatctt actctccaat
     5401 atttgggaca accagtaaat gctaatttgt cagtgactgt cactggccaa gatgaagcaa
     5461 gtccgaaaac tattttggga attgaagtaa gtcaggaacc gaaaaaagat tacctagttg
     5521 gtgatagctt agacttgtct gaaggacgct ttgcagtggc ttatagcaat gacaccatgg
     5581 aagaacattc ctttactgat gagggagttg aaatttctgg ttacgatgct caaaagactg
     5641 gtcgtcaaac cttgacgctt cgttaccaag gtcatgaagt caactttgat gttttggtat
     5701 ctccaaaagc agcattgaac gatgagtacc tcaaacaaaa attagcagag gttgaagctg
     5761 ctaagaacaa ggtggtctat aactttgctt caccagaagt aaaagaagct ttcttgaaag
     5821 caattgaagc ggccgaacaa gtgttgaaag accatgaaac tagcacccaa gatcaagtca
     5881 atgaccgact taataaattg acagaagctc ataaagctct gaatggtcaa gagaaattta
     5941 aggaagaaaa gacagagctt gatcgtttaa caggtgaggt tcaagaactc ttggctgcca
     6001 aaccaaacca tccttcaggt tctgccctag ctccgcttct tgagaaaaac aaggccttgg
     6061 ttgaaaaagt agatttgagt ccagaagagc ttgcaacagc gaaacagagt ctaaaagatc
     6121 tggttgcttt attgaaagaa gacaagccag cagtcttttc tgatagtaaa acaggtgttg
     6181 aagtacactt ctcaaataaa gagaagactg tcatcaaggg tttgaaagta gagcgtgttc
     6241 aagcaagtgc tgaagagaag aaatactttg ctggagaaga tgctcatgtc tttgaaatag
     6301 aaggtttgga tgaaaaaggt caagatgttg atctctctta cgcttctatt gtgaaaatcc
     6361 caattgaaaa agataagaaa gttaagaaag tatttttctt acctgaaggc aaagaggcag
     6421 tagaattggc ttttgaacaa acggatagtc atgttatctt tacagcacca cactttactc
     6481 attatgcctt tgtttatgaa tctgctgaaa aaccacaacc tgctaaacca gcaccacaaa
     6541 acaaagtcct tccaaaacct acttatcaac cggcttctga tcaacaaaag gctcctaaat
     6601 tggaagttca agaggaaaag gttgcctttc atcgtcaaga gcatgaaaat gctgagatgc
     6661 tagttgggga acaacgagtc atcatacagg gacgagatgg actgttaaga catgtctttg
     6721 aagttgatga aaacggtcag cgtcgtcttc gttcaacaga agtcatccaa gaagcgattc
     6781 cagaaattgt tgaaattgga acaaaagtaa aaacagtacc agcagtagta gctacacagg
     6841 aaaaaccagc tcaaaataca gcagttaaat cagaagaagc aagcaaacaa ttgccaaata
     6901 caggaacagc tgatgctaat gaagccctaa tagcagtctt agccagcctt ggtcttgcta
     6961 gtttagcctt gaccttgaga cggaaaagag aagataaaga ttaaatatcg aaaaatcttg
     7021 tgaaatcttt ccttatattt ccaaagtgtg atataatagt ttcgaataaa ataaataaag
     7081 gagtttttgt aacatggcaa aacttactgt taaagacgtt gacttgaaag gtaaaaaagt
     7141 cctcgttcgt gttgacttca acgtaccatt gaaagatggc gtaatcacta acgataaccg
     7201 tatcacagca gctcttccaa ctattaagta catcatcgaa caaggtggac gtgcaattct
     7261 tttctctcac cttggacgtg tgaaagaaga agctgataaa gctggcaaat cacttgctcc
     7321 tgtagcagct gacttggcag caaaacttgg tcaagatgtt gttttcccag gtgtcactcg
     7381 tggtgctgaa ttggaagcgg caatcaacgc tcttgaagat ggacaagttc tcttggttga
     7441 aaacactcgt tacgaagatg ttgacggcaa gaaagaatct aaaaacgatc ctgaacttgg
     7501 taaatactgg gcatcacttg gagatggtat cttcgtaaac gatgcattcg gtacagctca
     7561 ccgtgcacac gcatctaacg ttggtatctc agcaaacgtt gaaaaagcag ttgctggttt
     7621 ccttcttgaa aacgaaattg cctacatcca agaagcagtt gaaactccag aacgtccatt
     7681 cgtggctatc cttggtggtt caaaagtttc agacaagatc ggtgttatcg aaaacttgct
     7741 tgaaaaagct gataaagtcc ttatcggtgg tgggatgact tacacattct acaaagcaca
     7801 aggtatcgaa atcggtaact cacttgtaga agaagacaaa ttggatgttg cgaaagctct
     7861 tcttgaaaaa gcaaatggta aattgatctt gccagttgac tcaaaagaag ctaacgcatt
     7921 tgctggttac actgaagtgc gtgacactga aggtgaagca gtttctgaag gcttccttgg
     7981 tcttgacatc ggtccaaaat ctatcgccaa atttgacgaa gctttgactg gtgccaaaac
     8041 agttgtatgg aacggaccta tgggtgtatt tgaaaaccca gatttccaag ctggtacaat
     8101 cggtgtgatg gacgctatcg tgaaacaacc aggagttaaa tcaatcatcg gtggtggtga
     8161 ctcagctgcc gcagcgatta accttggccg tgcagacaag ttctcatgga ttagtacggg
     8221 tggtggagca tcaatggaac ttcttgaagg taaggttctt ccaggacttg cagccttgac
     8281 agaaaaataa gattttataa acaaatcaaa gaagagaggg atgaaagttc ctcttttctt
     8341 ttgcttaaaa taaaaacgct tcctctcaac tattactcat aaaaatcacc gatttatgat
     8401 aaaatggaaa tagaaagttg agattatgag ttattttaaa aaatataaat tcgataaatc
     8461 ccagttcaaa cttggtatgc gaacctttaa aacaggtatt gctgtttttc tagttctctt
     8521 gatttttggc ttttttggct ggaaaggtct tcaaattggt gctttgacag ccgtttttag
     8581 cctgagggag agttttgatg agagtgttca ttttgggact tcgcgtattc taggaaatag
     8641 tatcggtgga ctctatgcct tggtcttctt cttattaaat acttttttcc acgaagcctt
     8701 ttgggtgacc ttggtagttg ttccaatctg caccatgtta accattatga caaatgtagc
     8761 catgaataac aaagcagggg ttattggtgg tgtagcagct atgttaatca ttaccctatc
     8821 aattccaagt ggtgagacaa ttttgtacgt gtttgtgcgt gtattagaaa cgtttatggg
     8881 agtttttgtc gcaattatcg taaattacga tattgatcgt attcgtctct ttttagagaa
     8941 aaaagaaaaa taatgttaca ttttataaca ttatcaattg acgtttgtct ttttttagac
     9001 tataatagac agaaagaagg aaattgtaaa tgaaggaaaa agaatttcgc cgaaatatgg
     9061 ctgtttttcc tatcggcagt gttatgaagt tgaccgattt atcggcgcgt cagattcgtt
     9121 attatgaaga tcaagagttg atcaagcccg atcgaaacga aggaaatcgt cgcatgtatt
     9181 ccttgaatga catggatcgt ctgcttgaaa tcaaagatta tatctctgaa ggttataata
     9241 tcgctgccat taagaaaaaa tatgctgaac gtgaagcgaa atccaagaaa gcggttagtc
     9301 agactgaagt acgtcgtgca cttcacaatg aactcctcca acaggggcgt tttgcttcag
     9361 tacagtcacc ttttggtcgc ggttaggcaa ccgcaagtag tcatagatta aggagaaaac
     9421 ttatgccaat cacagctgca gatattcgtc gtgaagtcaa ggaaaaaaat gttaccttta
     9481 ttcgtcttat gttctcagat attttgggaa ccatgaaaaa cgtcgaaatt cctgctacag
     9541 atgaacagtt agataaggtc ttgtcgaaca aggttatgtt tgatggatct tctattgaag
     9601 gttttgtacg tatcaatgag tcggatatgt acttgtaccc ggacttggat acatggacag
     9661 tcttcccttg gggagatgaa aatggaagtg ttgcaggtct gatctgtgat gtctatacaa
     9721 cagaaggtga accatttgcg ggtgaccctc gtggtaattt gaaacgagct cttcgtcaca
     9781 tggaagaagt tggattcaaa tccttcaacc ttggtccaga gccagaattc ttcctattta
     9841 agttggatga aaatggggac ccaacacttg aagtgaatga caagggtggc tactttgatt
     9901 tggcacctac tgaccttgcg gacaacacac gtcgtgagat tgtgaatgtc ttgaccaaaa
     9961 tgggatttga agtagaagcg agtcaccacg aggttgcggt tggacagcat gagattgact
    10021 ttaagtacga tgaagttctc cgtgcttgtg ataagattca aatctttaag cttgttgtta
    10081 aaaccattgc tcgcaaacac ggactttacg caacatttat ggcgaagcca aaatttggta
    10141 ttgctggatc aggtatgcac tgtaatatgt ccttgtttga tgcagaagga aataacgcct
    10201 tctttgatcc aaatgatcca aaaggaatgc agttgtcaga aacagcttac catttcctag
    10261 gcggtttgat caagcatgct tacaactata ctgccatcat gaacccaaca gttaactcat
    10321 acaaacgttt ggttccaggt tatgaagcgc ctgtttacat tgcttgggct ggtcgtaacc
    10381 gttcgccact tgtgcgcgta cctgcttcac gtggtatggg aactcgtctt gagttgcgtt
    10441 cagtggatcc aatggcgaac ccttacattg ctatggctgt tcttttggaa gttggtttgt
    10501 atggtattga aaataaaatc gaagcaccag ctcctatcga agaaaatatc tacatcatga
    10561 cagcagaaga gcgcaaggaa gctggtatta cagaccttcc atcaactctt cacaacgctt
    10621 tgaaagcttt gacagaagat gaagtggtta aagctgctct cggagatcac atctacacta
    10681 gcttccttga agccaaacga atcgaatggg caagttatgc aaccttcgtt tcacaatggg
    10741 aaattgataa ttatttagac ctttactaat actaatatag aagaaagatt gcctgtgggt
    10801 aaacagtcac acagcagtct aagccatcaa atacctataa cccttaaaat agcgatttcg
    10861 gtcgctattt atttttcgaa aaatcctctt gactcttttg cgaattagat ttatcatcag
    10921 acgtgtagaa gaaaatcaag gagtcactat ggaaaaattc aatttcaaaa acaatatcgg
    10981 gcaagaaaac aagttacttc aaatcgaaat ctacaagttt actaactttt gcaagcttca
    11041 aaattacaca tctgtaaata ttttttcgaa agatatattt gaagccatag taaattgaga
    11101 ctagaatagt acactacatc tgctaaaaat ttctagaaat taatttaact ttcctaatcg
    11161 atttgtttac atcttatttc aatctactat attatctcaa taaatgatga tggcgactgt
    11221 tttgtttgtg cttgtcgatt tttgaatcct gatcgagcgg aagaatattt ctgccgaggt
    11281 tgtcaagggg aaaatcctga agatattgaa ttttatgatg aacaattaca ggcagaaaag
    11341 gtggaggctt tgaatattcg attggaagta aaaaattgaa ttatctacaa tctcatcaac
    11401 aataaaccta tttcaacccc attatctata ggcgtatttt tacgcctttt tatatacttg
    11461 aagcacataa gaaacattat gggaagtttg ctgatggaag tactcaagaa attgatgttc
    11521 cttatgatat tcctgatact tgggagtggg tgaggataaa atcaatttat tggaattttg
    11581 ggcaaaataa gccagagaaa tcctttaggt atatagatac gtctagtatt gatagaaaaa
    11641 agaacataat caactacaaa aatctacaat atctttcacc tgaacaagcg ccttcccgtg
    11701 ccagaaaatt agtttcgcag aatagtgtct tattttcaac agttagacca tatctaaaaa
    11761 atattgctgt agttagagaa cttaaagagt atttgatagc tagtacagca tttattgttt
    11821 tggatacttt acttaacgaa acatatttga aatattattt attatcagat aattttatca
    11881 atcgtgttaa taataaatct actggaacaa gttatcctgc aatcaatgat tataatttta
    11941 atctattatt aatt
//
LOCUS       DAVBDR010000059        11881 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.059, whole genome shotgun sequence.
ACCESSION   DAVBDR010000059 DAVBDR010000000
VERSION     DAVBDR010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11881)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11881)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11881
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.059"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            219..2510
                     /gene="pcrA"
                     /locus_tag="VQ540_001742"
     CDS             219..2510
                     /gene="pcrA"
                     /locus_tag="VQ540_001742"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000992850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HET2545507.1"
                     /translation="MNALLNGMNDRQAEAVQTTEGPLLIMAGAGSGKTRVLTHRIAYL
                     IDEKLVNPWNILAITFTNKAAREMKERAYSLNPATQDCLIATFHSMCVRILRRDADHI
                     GYNRNFTIVDPGEQRTLMKRILKQLNLDPKKWNERTILGTISNAKNDLIDDVAYAAQA
                     GDMYTQIVAQCYTTYQKELRQSESVDFDDLIMLTLRLFDQNPDVLTYYQQKFQYIHVD
                     EYQDTNHAQYQLVKLLASRFKNICVVGDADQSIYGWRGADMQNILDFEKDYPKAKVVL
                     LEENYRSTKTILQAANEVIKNNKNRRPKNLWTQNADGEQIVYYRADDELDEAVFVART
                     IDELSRSQNFLHKDFAVLYRTNAQSRTIEEALLKSNIPYTMVGGTKFYSRKEIRDIIA
                     YLNLIANLSDNISFERIINEPKRGIGLGTVEKIRDFANLQNMSMLDASANIMLSGIKG
                     KAAQSIWDFANMMLDLREQLDHLSITELVESVLEKTGYVDILNAQATLESKARVENIE
                     EFLSVTKNFDDTTDVTEEETGLDKLSRFLNDLALIADTDSGSQETSEVTLMTLHAAKG
                     LEFPVVFLIGMEENVFPLSRATEDPDELEEERRLAYVGITRAEKILYLTNANSRLLFG
                     RTNYNRPTRFINEISSDLLEYQGLARPANTSFKASYSSGSISFGQGMSLAQALQDRKR
                     GAAPKSIQSSGLPFGQFTAGAKSASSEANWSIGDIALHKKWGEGTVLEVSGSGARQEL
                     KINFPEVGLKKLLASVAPIEKKI"
     gene            2553..3233
                     /gene="radC"
                     /locus_tag="VQ540_001743"
     CDS             2553..3233
                     /gene="radC"
                     /locus_tag="VQ540_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000286923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HET2545508.1"
                     /translation="MYSISFQEDSLLPRERLAKEGVEALSNQELLAILLRTGTRQASV
                     FEIAQKVLNNLSSLTDLKKMTLQELQSLSGIGRVKAIELQAMIELGHRIHKHETLEME
                     SILSSQKLAKKMQQELGDKKQEHLVALYLNTQNQIIHQQTIFIGSVTRSIAEPREILH
                     YAIKHMATSLILVHNHPSGAVAPSQNDDHVTKLVKEACELMGIVLLDHLIVSHSNYFS
                     YREKTDLI"
     gene            complement(3230..3919)
                     /locus_tag="VQ540_001744"
     CDS             complement(3230..3919)
                     /locus_tag="VQ540_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HET2545509.1"
                     /translation="MKKPVIGITGNEKAHPDDDIMMSYAAKGFVEGVKDAGGIPIILP
                     IGDQEMACHYISLIDKLILTGGQNVDPKFYGEPKTIDSDDYNLQRDIFELALIKEAIK
                     QKKPIFSVCRGTQLFNVAMGGTLYQDIEDHWQDSSVEYTTQRLVTEPDTVLQEIYGEI
                     SHINSFHHQSIKDLAPNLKVVAHDPKDGIIEAVMSTDDVAFLGVQWHPELLFENRPKD
                     KKLFDYVVNEL"
     gene            complement(3937..4578)
                     /locus_tag="VQ540_001745"
     CDS             complement(3937..4578)
                     /locus_tag="VQ540_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HET2545510.1"
                     /translation="MKDKQFAIPKATAKRLSLYYRIFKRFHAEKIERANSKQIAEAIG
                     IDSATVRRDFSYFGELGRRGFGYDVKKLMTFFADLLNDNSITNVMLVGIGNMGHALLH
                     YRFHERNKMKIIMAFDLDDHPEVGTQTPDGIPIYGISQIKDKIKDADVKTAILTVPSV
                     KSQEVANLLVDAGVKGILSFSPVHLHLPKDVVVQYVDLTSELQTLLYFMRKED"
     gene            complement(4661..4876)
                     /locus_tag="VQ540_001746"
     CDS             complement(4661..4876)
                     /locus_tag="VQ540_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HET2545511.1"
                     /translation="MFELTYKDCYHVERTLKYEDHEALMLTLSGCVTLPDTLYVTSLT
                     FRGQKVYQGLVGDLYRFLSHADFLHQN"
     gene            complement(4884..5231)
                     /locus_tag="VQ540_001747"
     CDS             complement(4884..5231)
                     /locus_tag="VQ540_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HET2545512.1"
                     /translation="MAFEKIIQLKNCRYDYTLSPSVKKFTLKDNTFFETKVGNYELTR
                     LLEKVPNSGEGFQLKIIINKELTGAKINITDKFSLRLVDIFKSEDHHIHQEKFYFLMD
                     SLVERGVFTKSER"
     gene            complement(5236..6351)
                     /locus_tag="VQ540_001748"
     CDS             complement(5236..6351)
                     /locus_tag="VQ540_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HET2545513.1"
                     /translation="MIYLDNAATTPMSAVAISAMTKVMQETHGNPSSIHGHGRQAGKL
                     LREARQELAQLLRTKPQHIFFTSGGTEGNNTTIIGYCLRHQEQGKHIITTAIEHHAVL
                     ETIDYLVQHFGFEATIIQPENQEITAQQIQKALRDDTILVSTMFANNETGNLLPIAEI
                     GQILKQHPAAYHVDAVQAIGKIPIHSEELGIDFLTASAHKFHGPKGIGFLYASSMDFD
                     SYLHGGDQEQKKRAGTENLPAIVGMVAALKEDLEKQEEHFQHVQNLETAFLAELEGIQ
                     YYLNRGKHHLPYVLNIGFPGQKNDLLLLRLDLAGISISTGSACTAGVVQSSHVLEAMY
                     GANSERLKESLRISLSPQNTVEDLQTLAKTLKEIIGG"
     gene            complement(6361..7320)
                     /locus_tag="VQ540_001749"
     CDS             complement(6361..7320)
                     /locus_tag="VQ540_001749"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HET2545514.1"
                     /translation="MSDRKNMKLFALNSNQEIAQKIAQAVGVPLGKLSSRQFSDGEIQ
                     VNIEESVRGYDVYIIQSTSFPVNNHLMELLIMVDACVRASAHSINVVLPYFGYARQDR
                     IACPREPLTAKLVANMLVKAGVDRILTLDLHAVQVQGFFDIPVDNLFTVPLFAKHYCD
                     KGLLGSDVVVVSPKNSGVKRARSLAEYLDAPIAIIDYPQDDATRNEGYIIGDVEGKKA
                     ILIDDILNTGRTFSEASKIVEREGATEIYAVSSHGLFVEGAAELLDNTNIKEILVTDS
                     VATKEKTPKNVCYITASELIGDAIVRIHERKPVSPLFAYNKKK"
     gene            complement(7433..8002)
                     /locus_tag="VQ540_001750"
     CDS             complement(7433..8002)
                     /locus_tag="VQ540_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HET2545515.1"
                     /translation="MKHLEIELKTLLKKDEYNRLKDQFTGVTPVLQTNYYIDTPDFEL
                     REKKVAMRIRTFEDWAELTLKVPQSVGNMEYNQKLQLKDAEDYLSKEELPQGLVLDEL
                     AKHGIQSKNWQVLGCLTTLRYEMKTAIGLMALDQSRYFDITDYELELEVENHEQGKQD
                     FRQFLEKNQISYQKAPSKLVRFVKSMKNS"
     gene            8130..8801
                     /locus_tag="VQ540_001751"
     CDS             8130..8801
                     /locus_tag="VQ540_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HET2545516.1"
                     /translation="MTLEWEEFLDPYIQAVGELKIKLRGIRKQYRKQNKHSPIEFVTG
                     RVKPIESIKEKMARRGITYATLEHDLQDIAGLRVMVQFVDDVKEVVDILHKRQDMRII
                     QERDYITHRKASGYRSYHVVVEYTVDTINGAKTILAEIQIRTLAMNFWATIEHSLNYK
                     YQGDFPDEIKKRLEITARIAHQLDEEMGEIRDDIQEAQALFDPLSRKLNDGVGNSDDT
                     DEEYR"
     gene            8785..9603
                     /locus_tag="VQ540_001752"
     CDS             8785..9603
                     /locus_tag="VQ540_001752"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HET2545517.1"
                     /translation="MKNTGKRIDLIANRKPQSQRVLYELRDRLKRNQFILNDTNPDIV
                     ISIGGDGMLLSAFHKYENQLDKVRFIGLHTGHLGFYTDYRDFELDKLVTNLQLDTGAR
                     VSYPVLNVKVFLENGEVKIFRALNEASIRRSDRTMVADIVINGVPFERFRGDGLTVST
                     PTGSTAYNKSLGGAVLHPTIEALQLTEIASLNNRVYRTLGSSIIVPKKDKIELIPTRN
                     DYHTISVDNSVYSFRNIERIEYQIDHHKIHFVATPSHTSFWNRVKDAFIGEVDE"
     gene            9600..10496
                     /locus_tag="VQ540_001753"
     CDS             9600..10496
                     /locus_tag="VQ540_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HET2545518.1"
                     /translation="MRFEFIADEHVKVKTFLKKHEVSKGLLAKIKFRGGAILVNNQPQ
                     NATYLLDVGDYVTIDIPAEEGFETLEAIEHPLDILYEDDHFLVLNKPYGVASIPSVNH
                     SNTIANFIKGYYVKQNYENQQVHIVTRLDRDTSGLMLFAKHGYAHARLDKQLQKKSIE
                     KRYFALVKGDGHLEPEGEIIAPIARDEDSIITRRVAKGGKYAHTSYKIVASYGNIHLV
                     YIHLHTGRTHQIRVHFSHIGFPLLGDDLYGGSLEDGIQRQALHCHYLSFYHPFLEQDL
                     QLESPLPDDFSNLITQLSTNTL"
     gene            10540..11514
                     /gene="pta"
                     /locus_tag="VQ540_001754"
     CDS             10540..11514
                     /gene="pta"
                     /locus_tag="VQ540_001754"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HET2545519.1"
                     /translation="MEVFESLKANLVGKNARIVLPEGEEPRILQATKRLVKETEVIPV
                     LLGNPEKIKIYLEIEGIMDGYEVIDPQHYPQFEEMVSALVERRKGKMTEEDVRKVLVE
                     DVNYFGVMLVYLGLVDGMVSGAIHSTASTVRPALQIIKTRPNVTRTSGAFLMVRGTER
                     YLFGDCAININPDAEALAEIAINSAITAKMFGIEPKIAMLSYSTKGSGFGESVDKVVE
                     ATKIAHDLRPDLEIDGELQFDAAFVPETAALKAPGSTVAGQANVFIFPGIEAGNIGYK
                     MAERLGGFAAVGPVLQGLNKPVNDLSRGCNADDVYKLTLITAAQAVHQ"
BASE COUNT         3454 a         2273 c         2559 g         3595 t
ORIGIN      
        1 attatcaatc atgaactagg attctagttt tgcaggaagt ctattgaggt attgagctag
       61 tttatgaaaa aattgggtga aaaagtcgag tgttttagaa acccacagtg tagtattcta
      121 gtttcaatcc actatatttt gctactcccc gtaaagtttc tattttccct gatttctgat
      181 ataatagaaa tattgacttc aagagtaagg aagagaagat gaacgcatta ttaaatggaa
      241 tgaatgaccg tcaggctgag gcggtgcaaa cgacagaagg tcccttgcta atcatggcag
      301 gagctggttc tggaaagact cgtgttttaa cccaccgtat cgcttatttg attgatgaaa
      361 agctggtcaa tccttggaat atcttggcca ttacctttac caacaaggct gcgcgtgaga
      421 tgaaagagcg tgcttatagc ctcaatccag ctactcagga ctgtctgatt gcgaccttcc
      481 actccatgtg tgtgcgtatt ttgcgtcgcg atgcggacca tattggctac aatcgtaatt
      541 ttacaattgt ggatcctggt gaacagcgaa cgctcatgaa acgtattctc aaacagttga
      601 acttggatcc taaaaaatgg aatgaacgaa ctattttggg gaccatttcc aatgctaaga
      661 atgatttgat tgatgatgtt gcttatgctg ctcaagctgg cgatatgtat acgcaaattg
      721 tggcccagtg ttatacaacc tatcaaaaag aacttcgtca gtctgaatcc gttgactttg
      781 atgatttgat tatgctgacc ttgcgtctct ttgatcaaaa tcctgatgtt ttgacctact
      841 accagcaaaa attccaatac atccacgttg atgagtacca agataccaac cacgctcagt
      901 accaattggt caaactcttg gcttcccgtt ttaaaaatat ctgtgtggtt ggggatgcgg
      961 accagtctat ctacggttgg cgtggtgctg atatgcagaa tatcttggac tttgaaaagg
     1021 attaccccaa agctaaggtt gttttgttgg aggaaaatta ccgctcaacc aaaaccattc
     1081 tccaagcggc caacgaggtt attaaaaata ataaaaatcg ccgtcctaaa aatctctgga
     1141 ctcaaaacgc tgatggggag caaatcgttt actatcgtgc tgatgatgag ctggatgagg
     1201 ctgtatttgt agccagaacc atcgatgaac ttagtcgcag tcaaaacttc cttcataagg
     1261 attttgcagt tctctatcgg actaatgccc agtcccgtac aattgaggaa gccctgctca
     1321 agtctaacat tccttatacc atggttggcg gaaccaaatt ctacagccgt aaggaaattc
     1381 gcgatattat tgcttatctc aaccttattg ctaatttgag tgacaacatt agttttgagc
     1441 gtattatcaa cgagcctaaa cgtggaattg gtctaggtac agttgagaaa atccgtgatt
     1501 ttgcaaattt gcaaaatatg tctatgctgg atgcttctgc taatattatg ttgtctggta
     1561 tcaagggtaa ggcagcccaa tctatctggg attttgccaa tatgatgctt gatttgcggg
     1621 agcagctaga ccacttaagc attacagagt tggttgagtc cgtcctagaa aaaacaggtt
     1681 atgtcgatat tcttaacgcc caagcgactc tagaaagcaa ggcaagggtt gaaaatatcg
     1741 aagagtttct ttctgttacg aagaactttg atgacaccac tgatgtgaca gaagaggaaa
     1801 ctggtctgga caaactgagt cgtttcttaa atgacttggc tttgattgcc gacacagatt
     1861 caggtagtca ggagacatca gaagtgacct tgatgaccct gcatgctgcc aaaggtctcg
     1921 aatttccagt tgtctttttg attgggatgg aagaaaatgt ctttccactt agtcgtgcga
     1981 ctgaagatcc agatgaatta gaagaagagc gccgtctagc ctatgtaggt atcacgcgtg
     2041 cagagaaaat tctctatctg accaatgcca actcacgctt gctttttggt cgtaccaatt
     2101 ataaccgtcc gactcgtttt attaacgaaa tcagttcaga cttgcttgag tatcaaggtc
     2161 tggctcgtcc tgcaaataca agctttaagg catcatatag cagtggtagt atttcctttg
     2221 gtcaaggtat gagtttggct caggctcttc aagaccgtaa acgcggtgct gccccaaaat
     2281 cgatccagtc aagcggtctt ccatttggtc aatttacagc tggcgcaaaa tcagcatcta
     2341 gcgaggcaaa ttggtccatt ggtgacattg ctctccacaa gaaatgggga gagggaactg
     2401 ttctggaagt ttcaggtagc ggtgctaggc aggaattgaa aatcaatttc ccagaagtag
     2461 gtttgaaaaa acttttagcc agtgtggctc caattgagaa aaaaatctaa ttttccatcc
     2521 ttctcacgaa taataaagtg aggaggattt ttatgtacag tatttcattc caagaagatt
     2581 cactattacc aagagaaagg ctggccaagg aaggagttga agcgcttagt aaccaagagt
     2641 tgctagctat tttactcagg acaggaacac gtcaagctag cgtttttgaa attgcccaaa
     2701 aagtcttgaa caatctttca agcctaacgg atttgaaaaa aatgaccctg caggaattgc
     2761 agagtttgtc tggtattggg cgtgttaagg ccatagaatt acaagctatg attgaactgg
     2821 ggcatcgtat tcacaaacac gagactcttg aaatggaaag tattctcagc agtcaaaagt
     2881 tggccaagaa gatgcagcag gaattagggg ataaaaaaca agagcacctg gtggcactct
     2941 atctcaatac tcaaaatcaa atcatccatc agcagaccat ttttatcggt tctgtaactc
     3001 gtagtatcgc tgaaccgcga gagattcttc actatgcaat caagcatatg gcgacttctc
     3061 ttatcttggt ccacaatcat ccttcaggag cggtagcgcc tagccaaaat gatgatcatg
     3121 tcactaaact tgttaaagaa gcctgcgaat tgatggggat tgttctcttg gaccatttga
     3181 ttgtctctca ttctaattac tttagttatc gtgaaaagac agatttaatc taaagttcat
     3241 taacgacata gtcaaagagt tttttatctt tgggacgatt ttcaaaaaga agttctggat
     3301 gccattggac accgagaaag gcgacatcat ccgtactcat gacagcctca atgataccat
     3361 ctttaggatc atgagccaca acttttaaat ttggtgctaa gtccttgatg ctctggtggt
     3421 ggaaggagtt gatatgagag atttctccat agatttcttg gagaacggta tctggttctg
     3481 ttaccaagcg ttgagttgtg tactcaacag aagaatcctg ccaatggtct tcgatatctt
     3541 ggtacaaagt tccacccatg gcaacgttaa agagttgggt accacggcag acagagaaaa
     3601 tgggcttttt ctgtttaata gcttccttga tgagggccag ttcgaagata tctctttgaa
     3661 ggttatagtc atcgctatca atggttttgg gttcgccata aaattttgga tcgacatttt
     3721 gcccacctgt caagatgagc ttgtcaatca aactgatata gtggcaggcc atttcttgat
     3781 caccaatcgg taggatgatg ggaatccctc cagcatcttt aacgccttca acaaagcctt
     3841 ttgctgcgta gctcatcatg atgtcatcat ctggatgagc tttttcgttt cctgtaatcc
     3901 caataactgg ttttttcata aaatgatttt cgctttctaa tcctcttttc gcatgaagta
     3961 gaggagggtt tggagttcac ttgtcaaatc gacatactga acgaccacgt cttttggtaa
     4021 atgcagatgg actggtgaaa aactgagaat tcctttcaca ccagcatcaa ccaagagatt
     4081 agcaacctct tgtgacttga cgctgggaac agttaggata gcagtcttca catcagcatc
     4141 cttgatttta tccttgatct gagaaatccc gtaaatggga atcccgtcag gagtttgggt
     4201 accgacttca ggatggtcgt ctaggtcaaa ggccatgata atcttcatct tgttacgttc
     4261 gtggaagcgg tagtggagaa gggcatggcc catatttcca ataccaacca gcatgacatt
     4321 ggtaatagag ttgtcattga gcaaatcggc aaaaaatgtc attagttttt tgacatcata
     4381 gccaaaacca cgacgaccaa gttcaccaaa ataggaaaaa tcacgacgta cggtcgctga
     4441 atcaataccg atagcctctg caatttgctt agagttggca cgttcaatct tttctgcatg
     4501 aaatctctta aaaattcgat agtagagaga gagtcttttt gctgtagctt ttggaatagc
     4561 aaactgttta tctttcacaa aatcacaacc tttctattct tctattttat agaaacattg
     4621 tgaaaaaatc aacaaaaata agaaaaaact aagaaaaatc ttagttttga tgtaaaaaat
     4681 ctgcatgaga tagaaaacgg tagaggtctc cgaccagacc ctgataaact ttttggcccc
     4741 taaaagtcag agaagtcaca taaagtgtat ctggtaaggt tacacatcct gacaaagtca
     4801 acatgagagc ctcatgatcc tcatacttga gagtacgctc tacatgatag cagtccttat
     4861 aggtcagttc aaacattttg gctctatctt tccgattttg taaagacacc acgttctacc
     4921 aagctatcca tgaggaagta gaatttttcc tgatgaatat ggtggtcttc tgatttgaaa
     4981 atatcaacta gacgaaggct aaacttgtca gtgatattga ttttagcccc tgtaagttcc
     5041 ttgttaatga tgattttgag ttggaagcct tcaccgctgt ttggcacttt ttccaaaagg
     5101 cgagtcagtt catagttacc aaccttagtt tcaaaaaagg tgttatcttt gagggtgaat
     5161 tttttaacag aagggctaag agtgtaatcg taacgacaat tttttaactg aatgattttt
     5221 tcaaatgcca tatggctaac ctccgataat ttcttttaag gtttttgcga gggtttgtag
     5281 gtcttcaacg gtattttgtg gcgacaaact gatgcgaagg gattccttca agcgttctga
     5341 atttgcgcca tacatggctt caagaacatg gctggattgg acaacgcctg cagtacaggc
     5401 tgagccagta gagattgaaa ttccagctaa atctagccga aggagtaaga ggtcattttt
     5461 ctgaccagga aatccaatat tgagaacata agggagatga tgttttcctc tattcaagta
     5521 atactgaatg ccctccagct ctgccagaaa ggcggtttct agattttgta catgttgaaa
     5581 atgttcttct tgtttttcta ggtcttcttt tagggctgca accatgccta cgatagcagg
     5641 cagattttca gttcctgcac gttttttctg ttcctggtct ccgccatgta gataggaatc
     5701 aaagtccatg ctagatgcgt agagaaaacc gattccctta ggaccatgga atttgtgggc
     5761 agaagcagtg agaaaatcaa tgcccaattc ttctgaatga attgggattt taccaatagc
     5821 ctgaactgca tcaacatgat aggcagcagg gtgttgcttg agtatttggc caatttcagc
     5881 gatgggcagt aggtttcctg tctcattatt ggcaaacatg gtagaaacca aaatcgtatc
     5941 gtcacgtaaa gccttttgaa tttgctgggc tgtgatttct tgattttctg gctggataat
     6001 ggttgcttca aacccaaagt gttgaaccaa gtaatcaatt gtttcaagga cagcatggtg
     6061 ctcgatggca gttgtgatga tatgttttcc ttgttcttgg tgacgaagac agtagccaat
     6121 gatggtagta ttattgcctt cagtcccacc agaagtgaaa aagatatgtt gaggttttgt
     6181 ccttagtaac tgggctagtt cctgacgggc ttctcgcaag agtttgccag cttgacgacc
     6241 atgaccatga atactagaag gatttccgtg ggtttcttgc ataaccttgg tcatagctga
     6301 aatagcaact gctgacatag gagtcgttgc agcattgtcc aaataaatca aagaatcacc
     6361 ttatttcttt ttattgtagg caaagagtgg gctgactggt tttctttcgt gaatacggac
     6421 gatagcatca ccaattaact cactagcagt gatgtagcat acatttttag gagttttttc
     6481 ttttgttgct actgaatcag tcacaagaat ttctttaata ttagtattgt caagaagctc
     6541 agcagctccc tcgacgaaga gaccgtggct agaaacagca taaatttctg tagctccttc
     6601 acgttcaacg attttagaag cttcagagaa ggtacgtcct gtatttaaaa tatcatcaat
     6661 caagatagct ttcttacctt caacatcacc aataatataa ccttcgttac gagttgcatc
     6721 gtcttgaggg tagtcgataa tggcgatagg agcatcaaga tattcagcca ggctacgcgc
     6781 acgtttgaca cctgaatttt tagggctaac gacaacaaca tctgaaccaa gcaatccttt
     6841 atcgcagtaa tgttttgcga ataggggaac agtgaaaaga ttatccactg gaatatcaaa
     6901 gaaaccttga acctgaacgg catgcaaatc aagagtcagg atacgatcaa ctccagcctt
     6961 aaccagcata ttggcaacta gttttgctgt aagtggctca cgaggacaag caatgcggtc
     7021 ttgacgtgca tagccaaaat atggaaggac aacgttgata ctgtgggcac ttgcacgcac
     7081 acaagcatcg accatgatta acaattccat taggtggttg ttgacaggga aacttgttga
     7141 ttggatgatg taaacatcat aaccacggac actttcttcg atatttactt ggatttctcc
     7201 gtctgaaaat tgacgtgatg atagttttcc aagtgggaca ccaacagctt gggcaatttt
     7261 ttgtgcaatc tcttggttag agttgagtgc gaaaagtttc atgttttttc tatctgacat
     7321 tatagaccgt cctctgtaaa ctttataaat cctagttata tttaccttac atatatgaac
     7381 tgggatttgt gtatttttat cttttctatt ttaccaaaaa atggagatta tttcagctat
     7441 ttttcatact tttgacaaat cgaaccaatt ttgaaggagc tttttggtag gaaatctgat
     7501 ttttctctaa aaattgtcgg aaatcctgtt tgccttgctc atgattttcc acttcaagct
     7561 ccaattcgta atctgttata tcaaagtatc ggctctgatc cagtgccatg agaccaatag
     7621 ctgttttcat ttcatagcga agcgttgtta gacaaccaag aacctgccag ttcttacttt
     7681 ggataccatg tttcgccaat tcatccagta ctagtccttg aggaagttct tccttactca
     7741 gatagtcctc agcatctttt agttgcaatt tttggttgta ttccatgttt ccaacactct
     7801 gcgggacttt gagtgtcaac tcagcccagt cttcaaaggt tcgaatgcgc atagcgactt
     7861 tcttttctcg cagttcaaaa tcaggcgtgt cgatgtagta atttgtttga agaacaggag
     7921 tgacacctgt gaactggtct tttagacgat tgtattcatc ttttttcaat agtgttttca
     7981 attcaatttc taaatgtttc atttttctta ccttttttta tcgttgaaag cggatttatg
     8041 gtataataag cattgtattt attgtatatg aatctggaga aaaaatcaaa gatatttttg
     8101 acggataata tgagaacaag ggagaatata tgaccttaga atgggaagaa tttctagatc
     8161 cttacattca agctgttggt gagttaaaga ttaaacttcg tggtattcgt aagcaatatc
     8221 gtaagcaaaa taagcattct ccaattgagt ttgtgaccgg tcgagtcaag ccaattgaga
     8281 gcatcaaaga aaaaatggct cgtcgtggca ttacttatgc gaccttggaa cacgatttgc
     8341 aggatattgc tggcttacgt gtgatggttc agtttgtaga tgacgtcaag gaagtagtgg
     8401 atattttgca caagcgtcag gatatgcgaa tcatacagga gcgagattac attactcata
     8461 gaaaagcatc aggctatcgt tcctatcatg tggtagtaga atatacggtt gataccatca
     8521 atggagctaa gactattttg gcagaaattc aaattcgtac tttggccatg aatttctggg
     8581 caacgataga acattctctc aactacaagt accaagggga tttcccagat gagattaaga
     8641 agcgactgga aattacagct agaatcgccc atcagttgga tgaagaaatg ggtgaaattc
     8701 gtgatgatat ccaagaagcc caggcacttt ttgatccttt gagtagaaaa ttaaatgacg
     8761 gtgtaggaaa cagtgacgat acagatgaag aatacaggta aacgaattga tctgatagcc
     8821 aatagaaaac cgcagagtca aagggttttg tatgaattgc gagatcgttt gaagagaaat
     8881 cagtttatac tcaatgatac caatccggat attgtcattt ccattggcgg ggatggtatg
     8941 ctcttgtcgg cctttcataa gtacgaaaat cagcttgaca aggtccgctt tatcggtctt
     9001 catactggac atttgggctt ctatacagat tatcgtgatt ttgagttgga caagctagtg
     9061 actaatttgc agctagatac tggggcaagg gtttcttacc ctgttctgaa tgtgaaggtc
     9121 tttcttgaaa atggtgaagt taagattttc agagcactca acgaagccag catccgcagg
     9181 tctgatcgaa ccatggtggc agatattgta ataaatggtg ttccctttga acgttttcgt
     9241 ggagacgggc taacagtttc gacaccgact ggtagtactg cctataacaa gtctcttggc
     9301 ggtgctgttt tacaccctac cattgaagct ttgcaattaa cggaaattgc cagccttaat
     9361 aatcgtgttt atcgaacact gggctcttcc attattgtgc ctaagaagga taagattgaa
     9421 cttattccaa caagaaacga ttatcatact atttcggttg acaatagcgt ttattctttc
     9481 cgtaatattg agcgtattga gtatcaaatc gaccatcata agattcactt tgtcgcgact
     9541 cctagccata ccagtttctg gaaccgtgtt aaggatgcct ttatcggtga ggtggatgaa
     9601 tgaggtttga atttatcgca gatgaacatg tcaaggttaa gaccttttta aaaaagcacg
     9661 aggtttctaa gggattgctg gctaagatta agtttcgagg tggagctatt ctggtcaata
     9721 atcaaccgca aaatgcaacg tatctattgg acgttggaga ctacgttacc attgacattc
     9781 ccgctgagga aggctttgaa accttggagg ctattgagca tccattagat attctctatg
     9841 aggatgacca ctttctagtc ttgaataaac cctatggagt ggcttctatt cctagtgtca
     9901 atcactctaa caccattgcc aattttatca agggttacta tgtcaagcaa aattatgaaa
     9961 atcagcaggt tcacattgtt accagactag atagggacac ttctggcttg atgctctttg
    10021 ccaagcacgg ttatgcccat gcacgattag acaagcagtt gcagaagaaa tctatcgaga
    10081 aacgctactt tgctttggtt aagggagatg gacatttgga gccagaaggg gaaattattg
    10141 ctccgattgc gcgtgatgaa gattccatta ttaccagacg agtggctaaa ggcggaaagt
    10201 atgcccatac ttcatacaag attgtagctt cttatggaaa tattcacttg gtctatattc
    10261 acctgcacac tggtcgaacc catcaaatcc gagtccattt ttctcatatc ggttttcctt
    10321 tgctgggaga tgatttgtat ggtggtagtc tggaagatgg tattcaacgt caggctctgc
    10381 attgccatta cctatccttt tatcatccat ttttagagca agacttgcag ttagaaagtc
    10441 ccttgccgga tgatttcagt aaccttatta cccagttatc aactaatact ctataaaaac
    10501 tgtctcagag tataattatt atcttaaagg agaaaactca tggaagtttt tgaaagtctc
    10561 aaagccaacc ttgttggtaa aaatgctcgt atcgttctcc ctgaagggga agagcctcgt
    10621 attcttcaag caacaaaacg cttagtaaaa gaaacagaag tgattcctgt tttgcttgga
    10681 aatcctgaaa aaattaaaat ttatcttgaa attgaaggaa tcatggatgg ttatgaggtc
    10741 atcgaccctc aacattatcc tcaatttgaa gaaatggttt ctgccttggt ggagcgtcgc
    10801 aagggcaaaa tgactgaaga agatgtacgc aaggttttgg ttgaagatgt caactacttt
    10861 ggtgtgatgt tggtttactt gggcttggtt gatggaatgg tgtcaggagc gattcactca
    10921 acagcttcaa cagttcgtcc agctctacaa atcatcaaaa ctcgtccaaa tgtaactcgt
    10981 acttcaggag ccttcctcat ggttcgtggt acggaacgtt acctatttgg agactgtgcc
    11041 attaacatca atccagatgc agaagccttg gctgaaattg ccatcaactc agcaatcaca
    11101 gctaagatgt ttggcatcga acctaaaatt gccatgttga gctattctac taaaggttca
    11161 gggtttggtg aaagcgttga taaggtcgtt gaagcaacta aaattgctca cgacttgcgt
    11221 cctgaccttg aaatcgatgg tgagttgcaa tttgatgcag cctttgttcc tgaaactgca
    11281 gctctgaaag ctcctggaag tacggtagct ggtcaagcaa atgtcttcat cttcccaggt
    11341 atcgaggccg gaaatatcgg ttacaagatg gctgaacgcc tgggtggctt tgcggctgta
    11401 ggacctgttt tgcaaggttt aaacaagcca gttaatgatc tttctcgtgg atgtaatgca
    11461 gatgatgttt acaagttgac cctcatcaca gcagctcaag cagttcatca atagtgaaaa
    11521 ctataaagcg atatactatg ctatactgta gttatgaaac tatgtacgaa aagcactgcc
    11581 attaattcct gagaactaaa ttactgattg gtgtcaaaaa ggaaaacttc caagcgatga
    11641 tatcctgtct atacacgacc tatagaaatc tgtaatatgt atgtccgtaa aacgataatt
    11701 tccctttttg attttaaatg agtatgaaaa gagaattttt tcatgagaaa acgcataata
    11761 ttaagtgtct tgacacctgc tattatgcgt tttctggctc tttgtcaact gtagtgggtt
    11821 gaagaaaagc taagctcgag aaaggacaaa ttttgtcctt tcttttttga tattcagagc
    11881 g
//
LOCUS       DAVBDR010000060        11352 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.060, whole genome shotgun sequence.
ACCESSION   DAVBDR010000060 DAVBDR010000000
VERSION     DAVBDR010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11352)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11352)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11352
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.060"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            complement(275..883)
                     /locus_tag="VQ540_001755"
     CDS             complement(275..883)
                     /locus_tag="VQ540_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001165927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HET2545520.1"
                     /translation="MQIKFIDKVSNLIMLNLLYVASVVTVIAIGSGESALIATLIKIV
                     RHEESYPYRDFANSFFKDYWKNLGAALISNLPILILLFSLFFLPYIPLPIYIISILRH
                     IGVIYIILHLIATTFLIPLIGRYNNTLKNSLHNSIMLAYKHFFIAVLIRIIEIIPVLL
                     FFILQNQLLVWITLMIFILPSITKYANAFLYNFIFSKYEKLN"
     gene            1049..1219
                     /locus_tag="VQ540_001756"
                     /pseudo
     CDS             1049..1219
                     /locus_tag="VQ540_001756"
                     /inference="COORDINATES: protein motif:HMM:NF013577.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
     gene            1208..1819
                     /locus_tag="VQ540_001757"
     CDS             1208..1819
                     /locus_tag="VQ540_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001821036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HET2545521.1"
                     /translation="MTKDILELESQKMSSDTFIDEIKNNYLSIVESTRKLIDGRQIEL
                     AIKLIREANQILMIGVGSSGNAAREFESSLLRIGIISKTVIDTHFQLMHTALLKDNDL
                     IIAFSLSGSTKEVEETLLNAKRKNVKIISITNYSSRNIAKLSDCVLLTSKKESYLEGG
                     SLMAKASQLFIIDVICTRLSLINYEDTICKKEEIASLLSNKVE"
     gene            2536..3222
                     /locus_tag="VQ540_001758"
     CDS             2536..3222
                     /locus_tag="VQ540_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000448315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HET2545522.1"
                     /translation="METKKIKNLKGQIIVSCQALEGEPLYTPNGGVMPLLAKAAFQAG
                     AKGIRANSVRDISEIKEEVDLPIIGIIKRDYDGFEPFISATMKEIDELVSEGVDILAL
                     DCTNRSRPGYDNITDFIHDIKVKYPNQLLMAAISTFEEGKVAAESGVDFVGTTLSGYT
                     PYSPKKDNPDFELVERLVKELDVPVIAEGRISTPEQARKMLDLGAYAVVVGGAITRPL
                     EIAKKFIEVV"
     gene            3223..4155
                     /locus_tag="VQ540_001759"
     CDS             3223..4155
                     /locus_tag="VQ540_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001071049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET2545523.1"
                     /translation="MNQEILKKSKIQLTVEHIQKYWILYLMMIPATVLLILFTYGPMY
                     GIIMAFQDFTVFKGYTGSPFVGLKHFQRLFSDPLFYRLFKNTFMVGVLDFLFFFPAPL
                     IFALILNEVRKVRFKSVVQSISYLPHFIPLVVMVGIIFELFGSYGIINSLLSSLGMEP
                     ISFFTKSEWFLPLYIGSGVWKTIGWGSIIYMGALTNIDSTLYEAADMDGANRWHKMWH
                     VTLPSLRPTVVTLFILNAGGIMQVGFEKVFLMSSPATYEVSDVLSTYVYRQGILNSDF
                     SYSAAVGLFNNIVALLFVLLANKIAKKLGEEGIV"
     gene            4166..5095
                     /locus_tag="VQ540_001760"
     CDS             4166..5095
                     /locus_tag="VQ540_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000577774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HET2545524.1"
                     /translation="MIFSKNTKKSNRDKETFVDYLFIFILIIITLLMLYPLWWVVMTS
                     LSEPVWLSKNVVKLFPLKIDITAYKFIFGDSKLWQAYGNSVLYAALSTIVSVAVCSMY
                     AYPLTIPEIRGKKFWNTLILIPMFFSGGMIPLYIQVANLGLLNTAWALVLPGAVSTYY
                     IILFRTQFKSIPMELRESARIDGASEFRIFWNLVLPLSKVIFMIIALYCIVGSWNSFT
                     PPLLYLNDDTKMPLSIYLRNLVVTNTTDTAELSLSAGNTYYQQIAAQGGGIGMRIAIK
                     MGTIVVSVIPIMMIYPFIQKHFVKGILLGSVKG"
     gene            5109..6548
                     /locus_tag="VQ540_001761"
     CDS             5109..6548
                     /locus_tag="VQ540_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001178946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2545525.1"
                     /translation="MQNLKKYLLLDSGLVVGYTLENAQLKLNKLKKDTENNPLFGEEY
                     FAENPKLWEVRFDNSYPNVIYDKELKLYRCWYQTFVSDEASEETPLAERGEKEYIVKS
                     SRMTALCYAESKDGVKWEKPNLNLVKFKGSKDNNIVLMHAHGAGIMLDEQELDPKKRY
                     KLVSKLEFSPNLHYMVVVFSEDGIHFDEPIPWKKWNPAADSHNFPFRDPKTGKYAVIT
                     RTWANNVRLSAITFSDDFINWSEPKEILRGDGFEDQIYSMPVISYADIYLGFASMYHE
                     GDTLNENYDKVDLELKFSANLEQWDSVCKGDYLIERGGGVYPQNADFDASCIFTAAPI
                     IEDDKIWFYYMGGNGNHTGFRESSLARGYIKKDQFAYYTNKREGIPAKISTVSFQTYD
                     DEIYILADIPENGYIKVAVGTKYGNAYSDFGQEDISLVQVSDGKYKLEFNKKSILDLG
                     NSPVAFKFEIENAKLYGIEGSIQQHYLKY"
     gene            6617..8194
                     /locus_tag="VQ540_001762"
     CDS             6617..8194
                     /locus_tag="VQ540_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HET2545526.1"
                     /translation="MVKLNKVLKGSVAFLSASLLLAACGNNANSKPAEKTADGKTKIS
                     FLSTWQINDVRPPKDETLVGQWLEEQLGIDIDLVTIPGEGVSSKVNSLITSNQLPTVL
                     LTTGDKSDIAGINKLGKQGAFLDLSQHMDKLPNYKKYLEKNNALAQIEDDEKHIYAFT
                     KFFTDENIMYTTPILRKDLLVGSEFEDLSKIKTVDDYTKVLKYLTEKQGSPAFIQRNG
                     YEGFMKRVTPLWNLSHRTYYDYESDSYKHPVEQPQLKQFVEWLKELRKDNVLHPDWAV
                     MKDETWEGLLASNKGSFTVDRMNIIGDNNFDKSFDWQPLVYPEINGKRYLQPKTPYIS
                     DSGWVINANAPKEEIDKALEFFNFLYADENQEKLAIGFEGKTFTRENPNTQAGIKWLI
                     QIYGENAGNDKAELLFKHGNQAFTRVQTKLDIEAQPGTFPKVMYDQVDKIKKDLGGFR
                     PDTPVLSFTTEELDVLTKSEAGLNTFFDENIIKFIEGQRDMSEWDSFINEAKSKDLDK
                     VTKVYNDAYKRVKDRMK"
     gene            8254..9714
                     /locus_tag="VQ540_001763"
     CDS             8254..9714
                     /locus_tag="VQ540_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000272432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HET2545527.1"
                     /translation="MYDVVIIGAGSSGALAAIASGRLGLKTCLIEKGSRIGGVPINTL
                     MGSFANLYFDDSGRVNASKIVGELIERIIKKGGTVFNSMEELMNVNDFYQITIPYQPE
                     VYESVLTDMLIESKVDILLNVEVNNIIYDSKNIKSLEILSNQEVKLIDSKVFIDATGN
                     ATIASASGADVYEKNSSYGCLMRVGGVDISKTIEHIEKTKQWNYIEGYNQWLEEVLAN
                     RKYRATGAVLKDPVSYDHAPMLSKDDHFMNDEKWNYIKERWEKFRFIYTLEVSLFRNE
                     LKKAVESGDFNFEIYHDDKSGVTMNGDGISYGSWGQNVALINVAKAFGFNPKYMEDES
                     HANILSRKYNLTFLSFLKKYVPGFENSFILDQGTRATNRSCRHIDNSSMMDEILDFPM
                     YTFKTMYSYQTPKEITYKSIVGGKLNNLFVIGKGAYQSESFRSQISCMLMGISSAAAA
                     KTIIEDKSNTLNINRDLFKSNLDILFTWEFSNWITD"
     gene            9736..10191
                     /locus_tag="VQ540_001764"
     CDS             9736..10191
                     /locus_tag="VQ540_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001000318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT domain-containing protein"
                     /protein_id="HET2545528.1"
                     /translation="MNDTNKNQYFVYEFDTSFVEMSYSQFFEGYCILFSKEPYPSLSD
                     MPMEFRKEFLMEMSILGDAMLEVLNAYRINYDILGNSTPVLHAHLFPRYMWEEEERRK
                     TVVHRYDSSVFSNPEFEFTIEKHGPIIKKLRSAIDRHYREYQQLLDDSN"
     gene            10278..10683
                     /gene="cdd"
                     /locus_tag="VQ540_001765"
                     /pseudo
     CDS             10278..10683
                     /gene="cdd"
                     /locus_tag="VQ540_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221146.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
     gene            10696..11145
                     /locus_tag="VQ540_001766"
     CDS             10696..11145
                     /locus_tag="VQ540_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HET2545529.1"
                     /translation="MELVEFKNGHVNTVHEHIAITKVKEFLNNHDILKDKGGIHKIST
                     DFFYNIIDMETTTEENRPWESHKEYYDVHYLLNGEETILYNFLSQMELSEYKVDDDWQ
                     QMNGTALFSIKLKKDMLLLLEPNDAHRTGLLVEEPLNIKKVVFKVKI"
BASE COUNT         4047 a         1420 c         2045 g         3840 t
ORIGIN      
        1 acttagttct gtgcagtaca gaactaaatc ctttggataa attatttgtc taattttttg
       61 gggtcagtac agtattaaat accatgatct tatgcgtttt ataataaaaa atctgttctt
      121 gttttatttt tagaaaattt actaaagact aaaaatatta tgaataattt aaaaaatagt
      181 caggttatat agttttttga aattaaaatt attttatcgt tgaaattagt taaaaatttt
      241 tataaaatca agatgcaagg ctatgagatg ttctctagtt taatttttca tacttcgaga
      301 atataaagtt atataaaaat gcattagcat attttgttat tgagggaagt ataaaaatca
      361 ttaaagttat ccaaactagt aattgattct gtaatataaa gaagagtaga actgggataa
      421 tttcaataat tctaataaga acggcaataa aaaaatgttt ataggctaac atgattgaat
      481 tgtgtagaga attttttaaa gtgttattat atctaccgat taaaggaatt agaaatgttg
      541 ttgctattaa atgaagtatg atatatatta ctccaatatg tcgtaagata gaaatgatat
      601 atataggtaa tggtatgtag ggtaggaaga acaaactgaa taataagatt aaaattggta
      661 aattagatat taatgctgct cctaaatttt tccaataatc tttaaaaaaa ctgtttgcga
      721 agtctctata gggataggat tcctcgtgtc gtacaatttt tattagagtt gctattaggg
      781 cactttcacc tgatccgata gcaataactg ttactactga cgctacatag agtagattta
      841 acattataag atttgaaact ttatcaataa attttatctg catctttaac tcctgctgtt
      901 tttatactta taatatcaca tcatttgagt ttcatcaact ttgaatacat taagaaagaa
      961 tataactatg aggaaaggaa aaaattatta tgaataaatc caaaaaatat aaagaaagaa
     1021 ttcattatga atacgataat cttactaaat cagagaaaaa attgctgact atattttagt
     1081 tagagatagt gaaatagttt atgaaacgtc ttcagaaatt gttagtaaag taaaagttgg
     1141 agagggaact cttaatcgat tttgcaaaaa gattggatac tctggttttc aggaactaaa
     1201 attaaaaatg acgaaagata tattagagtt agaatctcaa aaaatgagta gtgacacatt
     1261 tattgatgaa ataaaaaata attatttatc tattgtggaa agtacaagaa aattaattga
     1321 tggtagacaa atagaattag ctataaaatt aataagagaa gcaaaccaga ttttaatgat
     1381 tggtgtgggt tctagtggaa atgcggctag agaatttgag agtagtttgt taagaattgg
     1441 aataataagt aagacggtaa ttgataccca ttttcaactc atgcatactg cgttattgaa
     1501 agataatgat ttgataatag cgtttagttt atctggttcc acaaaagaag ttgaggaaac
     1561 tttattaaac gcaaaaagaa aaaatgttaa aattatttca ataacaaatt attcgtccag
     1621 aaatatagca aaattatctg actgcgttct tttgacatca aaaaaagaat cttatttaga
     1681 gggtggtagt ttaatggcta aggcttctca actattcata attgatgtaa tatgcactag
     1741 actctcttta ataaattatg aagatactat atgtaaaaaa gaagagattg cttctttgct
     1801 gtcaaataaa gtggaataaa tcaataattt ttaaatttta ataaaaattt tttaaaataa
     1861 attaaaaaac gatcctaaaa gggtcgtttt tttgctaaag ttttaaaaat aaacaataat
     1921 taagattata gtgcgttgaa tctatattag gacataacaa ttcttaaatc attgttagaa
     1981 attagtttga attttccaat caatttgttc gatttttaca tcattgcatt atatcacgtg
     2041 actattaacc ttgttttctc ctaaaattga ttttcttctt ttcttatctt gtccactcga
     2101 aacaagtatt gtaagaattt gattattttt gaaagtactt ttaatatatt tgagatagtt
     2161 aaaaaagatt tgaaactaaa ttccaaatta gaaaaagact tgaaatgcta aaaaaaaaaa
     2221 gtatactcta attgaaaacg gtaacaaaac taatttagag aatgaaatat agagtatttc
     2281 tctcttaaaa gtttttggtg aaacgagatg tagaaaggag atttagccaa agagtctatt
     2341 agtgctagaa taatagatta gaattatagt gtattgaatc tataacagta cgccttaaat
     2401 gctaaaatat ttctataaat taatttaact ttcctgatag ggctgttcat atcttatttc
     2461 aattcactat ataaataaaa ttgtagtaga tgttattgaa ttagtaaaaa aaataaaaaa
     2521 acggaggttt tctgaatgga aactaaaaaa attaaaaatt taaaaggtca aataattgtt
     2581 tcctgccaag cgttagaagg agagccactt tatactccaa atggaggagt gatgccgtta
     2641 ttagcaaaag ccgcctttca agcaggcgct aaaggtattc gtgctaattc tgtccgcgat
     2701 atttcagaaa taaaagaaga agttgactta ccaattatag gtatcataaa aagagattac
     2761 gatggctttg aaccttttat ttcagcaact atgaaagaga ttgatgaatt agttagtgaa
     2821 ggagtagaca ttttagcttt ggattgtact aatcgttcaa gaccaggtta tgataatatt
     2881 actgacttta ttcatgatat taaagtcaag tatccaaacc aattattaat ggctgctatt
     2941 tctacttttg aagaagggaa agtagctgct gaatcgggag tagattttgt gggtacgaca
     3001 ttatctggtt atacaccata tagccctaaa aaagataatc ctgattttga gttagttgaa
     3061 agattggtaa aagagcttga cgtaccagtt attgctgaag gaagaataag tactccggaa
     3121 caagctagaa aaatgttaga tttaggtgct tacgcagtgg ttgttggagg agctatcact
     3181 cgtcctttgg aaatagcgaa gaagtttatt gaggtagttt agatgaatca agaaatatta
     3241 aaaaagagta agattcaatt gacagttgaa catattcaaa aatattggat tttatattta
     3301 atgatgattc cagcaactgt tctactaatt ttatttacgt atggaccaat gtacggcatt
     3361 attatggcct ttcaagactt tactgtcttc aagggatata ctggaagtcc atttgtcggt
     3421 ttaaaacatt ttcaaagatt gttctcagat cctttgtttt atagattgtt caagaatacg
     3481 ttcatggtag gggttttaga ttttttattc tttttcccag ctccgcttat ttttgcactc
     3541 atattaaacg aagtcagaaa agtaagattt aagagtgtag ttcaatctat tagttatctt
     3601 cctcatttta ttcccctagt ggttatggtt ggtattattt ttgaactatt tggttcatat
     3661 ggtattatta acagtttact ttcatcactt ggaatggagc caataagttt ctttacaaaa
     3721 tctgaatggt tcttgcctct ctacattggt tcaggagtat ggaaaacaat aggttggggt
     3781 tctatcattt atatgggagc attaaccaat atagattcaa ctttatatga agcagcagat
     3841 atggacgggg ctaatagatg gcacaaaatg tggcatgtaa ctctaccaag tttaagacct
     3901 acagtagtta ctttgtttat actaaatgct ggtggtatca tgcaagtagg atttgaaaag
     3961 gtattcttga tgtctagtcc tgcaacatat gaagtatctg atgtattatc tacttatgtt
     4021 tatagacaag gtattttaaa ttctgatttc agttactcag ctgcagtagg attatttaat
     4081 aacatagtag ctttgttatt tgttttatta gctaataaga ttgctaaaaa acttggcgaa
     4141 gaaggaattg tataaggggg gtaaaatgat tttttcaaaa aatacaaaaa agagtaatag
     4201 agacaaagaa accttcgttg attatctctt tatattcatt ttaataataa taaccttact
     4261 tatgttgtat ccattatggt gggtagtgat gacgtcactt tcagaaccag tttggctatc
     4321 taaaaacgtt gttaaattat ttcccttaaa aatagatatt actgcatata agtttatttt
     4381 tggggattct aaactatggc aagcatatgg taatagtgta ttgtatgctg cactatctac
     4441 aattgttagt gttgcggtat gtagtatgta tgcctatcca cttacaattc ctgaaattag
     4501 gggtaaaaaa ttctggaata ctcttatttt gattccaatg ttctttagtg gaggaatgat
     4561 cccgctttat atacaagttg caaacctcgg tttattgaat actgcttggg ctcttgtttt
     4621 acctggtgct gtttctacat attatataat tttgtttaga acacagttta aatcaatccc
     4681 aatggagctt cgtgagtctg ctagaattga tggggcaagt gaatttagaa ttttttggaa
     4741 tttagtatta ccattatcaa aagttatttt catgattata gcactttatt gcatagttgg
     4801 ttcatggaat agttttactc ctccattact ttatttgaat gacgacacta agatgccttt
     4861 atctatttat ttgagaaatt tagtcgttac aaatacaact gatactgctg aattatcact
     4921 ttctgcaggt aatacatatt accaacaaat tgctgctcaa ggtggaggta ttggtatgcg
     4981 tattgctatt aagatgggta ctattgttgt tagtgttatt ccaattatga tgatttatcc
     5041 atttattcag aaacattttg ttaagggaat cctgctaggt tctgtgaaag gttaataagg
     5101 taattatttt gcaaaattta aaaaaatatc ttttattaga tagcggttta gtagttgggt
     5161 atacattaga aaatgctcaa ttaaaattaa ataagctaaa aaaagatact gaaaacaatc
     5221 cactatttgg tgaagagtat tttgccgaaa atcctaaatt atgggaagtt cgttttgata
     5281 attcatatcc aaacgttatc tatgataaag aattgaaatt atatagatgt tggtatcaaa
     5341 catttgttag tgatgaagca agcgaagaga ctcctttagc agaacgtgga gagaaggaat
     5401 acattgtcaa gtcatctaga atgacagcac tttgctatgc tgaaagtaaa gatggagtaa
     5461 aatgggaaaa accaaatctc aatctagtaa aatttaaagg ttcaaaagat aataatattg
     5521 ttctgatgca tgcacacggt gcaggtatca tgctagatga acaggagttg gatcctaaga
     5581 aacgatataa attagtttca aaattagaat tttctccgaa tcttcattac atggttgttg
     5641 ttttttcaga agacggtatt cattttgacg aacctattcc atggaaaaaa tggaatcctg
     5701 cagcagatag tcataatttt ccatttagag atccaaaaac tggtaaatac gctgttatta
     5761 caagaacctg ggcaaataac gtacgtctaa gtgcaattac tttcagtgat gattttatta
     5821 attggtcaga acctaaagaa atccttaggg gagatggatt tgaagatcaa atttattcta
     5881 tgccagtaat ttcatacgcg gatatctatt taggttttgc ttcaatgtac catgaaggcg
     5941 acactttaaa tgaaaactat gataaagtag acttagaatt gaaattctct gctaatttgg
     6001 aacaatggga tagtgtatgt aagggcgact atctcattga aaggggaggt ggagtatacc
     6061 cgcagaatgc tgattttgat gctagttgta ttttcacggc tgctccaata attgaagatg
     6121 ataagatttg gttctactat atgggtggaa atggtaatca cactggcttc cgagaaagtt
     6181 cattagctag aggatatatt aagaaagacc aatttgctta ttatactaat aagagagaag
     6241 gaattccagc taaaatatct acagttagct tccaaactta cgatgatgaa atttatatct
     6301 tagctgatat tcctgaaaat ggttatatta aagttgcggt aggtactaaa tacggtaatg
     6361 cttattcaga tttcggtcag gaagatatct ctcttgttca agtttccgat ggtaagtata
     6421 agttggaatt taataaaaaa tctatcttag atttaggtaa ttctccagtt gcgttcaaat
     6481 ttgaaatcga gaatgcaaaa ttgtatggta ttgaaggtag tattcagcaa cactatctca
     6541 aatattaacc agaataattc gttaacaaat aatctctata ttagtggaga tagatatata
     6601 aaatggaggt cttattatgg taaagcttaa taaggtatta aaagggagtg ttgcattcct
     6661 gagtgcaagt ttattgctag cagcttgtgg caataacgct aattcaaagc ccgctgaaaa
     6721 aacagctgat ggtaaaacga aaatttcgtt tctatctaca tggcaaatta atgatgttcg
     6781 tccgcctaaa gatgaaacac ttgttggtca atggttagaa gaacagctag gtattgatat
     6841 tgatcttgta actattcctg gcgagggagt aagttctaaa gtaaattctc ttattactag
     6901 taaccagtta ccgactgttt tgttgacaac aggagataag agtgatatcg ctggtatcaa
     6961 caaacttggt aaacagggtg cattcttaga tttgtcacaa cacatggaca aactaccaaa
     7021 ctataagaag taccttgaaa aaaataatgc attagctcaa atagaagatg atgaaaaaca
     7081 tatttatgct ttcacaaaat tctttactga tgagaatatc atgtatacta caccaattct
     7141 gagaaaagac ttacttgttg gttcagaatt tgaagatctt tcaaaaatta aaactgttga
     7201 tgactataca aaagttttga aatatttgac tgaaaaacaa ggttctccag catttattca
     7261 acgtaatggc tatgaaggct tcatgaagcg agttacacca ttgtggaatt taagccatcg
     7321 tacatactat gactatgaat cagattcata taaacatcca gttgaacaac ctcaattgaa
     7381 acaattcgtt gaatggttga aagaattacg taaagataac gtacttcacc ctgactgggc
     7441 agttatgaaa gatgaaactt gggaaggtct attggcttct aacaagggtt cattcactgt
     7501 tgaccgtatg aatatcattg gagataataa ctttgataaa tcatttgatt ggcagccact
     7561 tgtttatcca gaaattaatg gaaaacgtta tttgcaaccg aaaacaccgt acatttctga
     7621 ttcaggttgg gtaatcaatg ccaatgcacc aaaagaagaa attgataaag cgttagaatt
     7681 ctttaatttc ttatacgctg atgaaaatca agaaaaactt gctattggat ttgaaggtaa
     7741 aacatttaca cgtgaaaacc ctaatactca agcaggtatt aaatggttga ttcaaattta
     7801 cggtgaaaat gctggaaatg ataaagcaga actgctgttt aaacatggta accaagcatt
     7861 tactcgcgtt caaactaaat tagatattga ggcacagcca ggaacattcc ctaaagttat
     7921 gtatgatcaa gtagataaaa ttaagaaaga tttaggtggt tttagaccag atactccggt
     7981 tctttccttt acaactgaag aattagatgt tttaactaaa tctgaagcag gattaaatac
     8041 tttctttgat gaaaatatta ttaaattcat tgaaggacaa agagatatga gtgagtggga
     8101 ttcatttatc aatgaagcta aatctaaaga cttggataaa gttacaaaag tatataatga
     8161 tgcctacaaa cgtgtcaaag atagaatgaa atagactaaa tggtagctct ctggtttttc
     8221 agagagctac tactgcctga gggggagtaa gctttgtatg atgtagtaat tataggtgca
     8281 ggaagttcgg gcgcattggc tgcaattgct tcggggcgtc tagggttaaa aacttgtcta
     8341 atagagaagg gaagtagaat tggtggagtt cctattaata cactaatggg gtcatttgct
     8401 aatctatatt ttgatgattc tggtagagta aatgcaagta aaattgttgg ggaattaata
     8461 gaacgtatta tcaaaaaagg tggtactgtc tttaactcta tggaagaatt gatgaatgta
     8521 aatgattttt atcagattac aattccctat caaccagaag tttatgaatc ggttttaact
     8581 gatatgttga ttgagtctaa agttgatatt ttactaaatg ttgaagttaa taatattatt
     8641 tatgatagta aaaatattaa aagtcttgaa attttaagta atcaggaagt taaattgatt
     8701 gattctaaag tttttattga tgctacaggg aatgcaacaa ttgcttctgc tagtggagct
     8761 gatgtttatg aaaaaaattc ttcttacggt tgtttaatga gagttggagg agttgatatc
     8821 tcaaagacta tagaacatat tgaaaaaaca aagcagtgga actatataga aggatataat
     8881 cagtggttag aagaagtatt agcaaatcga aagtacagag ccactggagc agttttaaaa
     8941 gatccagttt cttatgatca tgcccctatg ctttcaaaag acgaccattt tatgaatgat
     9001 gaaaaatgga attacattaa agaaagatgg gaaaaattta gatttattta cactttagaa
     9061 gtatcactat ttaggaatga attaaaaaaa gctgtagaat ctggggattt taattttgaa
     9121 atttatcatg atgataaatc tggagtcact atgaatggcg acggtataag ctatggttca
     9181 tggggtcaaa atgtagcatt aattaatgtt gcaaaagcat ttggattcaa tcccaaatat
     9241 atggaagatg aatcacatgc taatattctt tctagaaaat ataatttaac atttttatct
     9301 tttcttaaaa aatatgtacc aggttttgaa aattctttta tccttgatca gggaactaga
     9361 gctactaaca gatcatgtag gcacattgat aattcatcta tgatggacga aattcttgat
     9421 tttccaatgt atacatttaa gactatgtat agctatcaaa ctcctaaaga aataacgtac
     9481 aaatcaattg taggtggaaa attgaataat ttgtttgtaa taggtaaagg tgcttaccaa
     9541 tccgaaagtt ttagatcaca aattagttgt atgttaatgg ggatatcatc agcagcagcg
     9601 gcaaaaacta ttattgaaga taaaagcaat actctaaaca ttaatagaga tttgtttaaa
     9661 tcgaacttag atatattatt tacatgggag ttttctaatt ggattactga ttaacaaata
     9721 ataagggaat attaaatgaa tgatactaat aaaaatcaat actttgttta tgaatttgat
     9781 actagctttg tagaaatgtc ttattctcag ttttttgaag gatattgtat tcttttttca
     9841 aaagaaccct atccttcttt atctgatatg ccaatggaat ttagaaaaga atttttaatg
     9901 gaaatgagta tattaggtga tgcgatgctt gaagtgttaa atgcctatag aattaattat
     9961 gatatcttag gaaattcaac acctgtactt catgctcatt tatttccgag atacatgtgg
    10021 gaagaggaag agagaagaaa aactgtagtt catagatatg attcttcagt ttttagcaat
    10081 cctgagtttg aatttactat agaaaagcat ggaccaatta ttaaaaaact gaggtctgct
    10141 attgatagac attatagaga gtatcaacaa ttattagatg attcaaactg aactccacat
    10201 tttcgattag atttaatacc ttgtatatta caactaggtt gtggatgata taattttttg
    10261 aaaaatatat tttaggaatg acttataaag caattatatc agaggctatt aaatcaatgg
    10321 ccaaagctta tgctccttat tctgatttta aggttggagc tgcgttagta actgaagata
    10381 aaaaattttt tctggatgta atatagaaaa tgctgctttt tctcctactt gctgtgcaga
    10441 acgagtatct ttttataaag ctgtatttaa aggagaacgt tcgttttcaa gaacatgtat
    10501 tgtaggtgga aaaaatggta tcttatcatc ttttatagca ccttgcggag tgtgtcgcca
    10561 ggtaatgata gaatttgtaa tcctgattca tttgaagtta tattggctag tgatgttgat
    10621 acttataaag tatataaact taaagaacta ctaccagtta gttttaatca agaaaattta
    10681 taacaggagg gaactatgga attagttgaa tttaaaaatg gacatgttaa tacggttcat
    10741 gagcatatcg caataacgaa agtaaaagag tttctaaata atcatgatat attaaaagat
    10801 aaaggtggca tacataaaat ttctactgat ttcttttaca atataattga tatggaaact
    10861 acaactgaag agaatagacc gtgggaaagt cataaggaat attatgatgt ccattatctg
    10921 ttaaatggag aagaaacaat tttatataac ttcttgtctc aaatggaatt gtctgaatat
    10981 aaagtagatg atgattggca acaaatgaat gggacagctt tatttagtat taaattaaag
    11041 aaagatatgt tacttttgtt ggaaccaaac gatgcacata gaacaggcct attggttgaa
    11101 gaaccactta atattaagaa agttgttttt aaggtaaaaa tttaactgaa agtactttcg
    11161 gggattaaga attttaaaat atttaagaaa ttgtattcta aagttctaaa attatagata
    11221 tttaatttaa agcttgttaa aatagaatag taacactcat ctgctttcaa aaagcattct
    11281 attccatctc cgattaacga tggactttat cacctccttc tccagtcctt gtatgacatc
    11341 ttggagttga tt
//
LOCUS       DAVBDR010000061        11187 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.061, whole genome shotgun sequence.
ACCESSION   DAVBDR010000061 DAVBDR010000000
VERSION     DAVBDR010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11187)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11187)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11187
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.061"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            complement(<1..947)
                     /locus_tag="VQ540_001767"
     CDS             complement(<1..947)
                     /locus_tag="VQ540_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001083019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HET2545530.1"
                     /translation="MNRYAVQLISRGAINKMGNMLYDYGNSVWLASMGTIGQTVLGMY
                     QISELVTSILVNPFGGVISDRFSRRKILMTADLVCGILCLAISFIRNDSWMIGALIVA
                     NIVQVIAFAFSRTANKAIITEVVEKDEIVIYNSRLELVLQVVGVSSPVLSFLVLQFAS
                     LHMTLLLDSLTFFIAFILVTFLPKEEAKVQEKKAFTGRDIFVDIKDGLHYIWHQQEIF
                     FLLLVASSVNFFFAAFEFLLPFSNQLYGSEGAYASILTMGAIGSIIGALLASKIKANI
                     YNLLILLALTGVGVFMMGLPLPTFLSFSGNLVCELFMTI"
     gene            complement(1027..1890)
                     /locus_tag="VQ540_001768"
     CDS             complement(1027..1890)
                     /locus_tag="VQ540_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012291596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HET2545531.1"
                     /translation="MEHLGKVFREFRTSGNYSLKEAAGESCSTSQLSRFELGESDLAV
                     SRFFEILDNIHVTIENFMDKARNFHNHEHVSMMAQIIPLYYSNDIAGFQKLQREQLEK
                     SKSSTTSLYFELNWILLQGLICQRDASYDMKQDDLDKVADYLFKTEEWTMYELILFGN
                     LYSFYDVDYVTRIGREVMEREEFYQEISRHKRLVLILALNCYQHCLEHSSFYNANYFE
                     AYTEKIIDKGIKLYERNVFHYLKGFALYQKGQCKEGCKQMQEAMHIFDVLGLPEQVAY
                     YQEHYEKFVKS"
     gene            complement(1893..3794)
                     /locus_tag="VQ540_001769"
     CDS             complement(1893..3794)
                     /locus_tag="VQ540_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000584877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HET2545532.1"
                     /translation="MIILQANKIERSFAGEVLFDNINLQVDERDRIALVGKNGAGKST
                     LLKILVGEEEPTSGEINKKKDISLSYLAQDSRFESENTIYDEMLHVFNDLRRTERQLR
                     QMELEMGEKSGEDLDKLMSDYDRLSENFRQAGGFTYEADIRAILNGFKFDESMWQMKI
                     AELSGGQNTRLALAKMLLEKPNLLVLDEPTNHLDIETISWLENYLVNYSGALIIVSHD
                     RYFLDKVATITLDLTKHSLDRYVGNYSRFVELKEQKLATEAKNYEKQQKEIAALEDFV
                     NRNLVRASTTKRAQSRRKQLEKMERLDKPEAGKKAANMTFQSEKTSGNVVLTVENAAV
                     GYDGEVLSQPINLDLRKMNAVAIVGPNGIGKSTFIKSIVDQIPFIKGEKRFGANVEVG
                     YYDQTQSKLTPSNTVLDELWNDFKLTPEVEIRNRLGAFLFSGDDVKKSVGMLSGGEKA
                     RLLLAKLSMENNNFLILDEPTNHLDIDSKEVLENALIDFDGTLLFVSHDRYFINCVAT
                     HVLELSENGSTLYLGDYDYYVEKKATAEMSQTEEASTSNQAKEASPVNDYQAQKESQK
                     EVRKLMRQIESLEAEIEELESQSQAISEQMLETNDADKLMELQAELDKISHRQEEAML
                     EWEELSDQV"
     gene            complement(4222..4497)
                     /locus_tag="VQ540_001770"
     CDS             complement(4222..4497)
                     /locus_tag="VQ540_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002950996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HET2545533.1"
                     /translation="MANKQDLIAKVAEATELTKKDSAAAVEAVFAAVADYLAAGEKVQ
                     LIGFGNFEVRERAERKGRNPQTGKEMTIAASKVPAFKAGKALKDAVK"
     gene            complement(4603..5442)
                     /locus_tag="VQ540_001771"
     CDS             complement(4603..5442)
                     /locus_tag="VQ540_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000161411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HET2545534.1"
                     /translation="MTKIKIVTDSSVTIEPELVKQLDITIVPLSVMIDNVVYSDADLK
                     EEGKFLQLMQESKNLPKTSQPPVGVFAEIFEDLCKDGGQILAIHMSHALSGTVEAARQ
                     GASLSTADVIVVDSSFTDQALKFQVVEAAKLAQEGKDMEAILSHVEEVKNHTELYIGV
                     STLENLVKGGRIGRVTGLLSSLLNIRVVMQMKDHELQPMVKGRGTKTFKKWLDELITS
                     LSERAVAEIGISYSGSDDWAKEMKESLQAYVEKPISVLETGSIIQTHTGENAWAILIR
                     YHS"
     gene            5584..6432
                     /locus_tag="VQ540_001772"
     CDS             5584..6432
                     /locus_tag="VQ540_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000592058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HET2545535.1"
                     /translation="MIKKIYPIFTILLGAAIYAFGLTYFVVPHHLFEGGATGITLITF
                     YLFKIPVSLMNLLINIPLFILAWKIFGAKSLYSSLLGTLALSGWLAFFEHIPLHIDLQ
                     GDLLITALIAGILLGIGLGIIFNAGGTTGGTDILARILNKYTHISIGKLLFILDFCIL
                     MLILLIFKDLRLVSYTLLFDFIVSRVIDLIGEGGYAGKGFMIITKRPDQLAKAINDDL
                     GRGVTFISGQGYYSKENLKIIYCIVGRNEIVKTKEMIHRIDPQAFITITEAHEILGEG
                     FTFEKE"
     gene            complement(6525..7442)
                     /locus_tag="VQ540_001773"
     CDS             complement(6525..7442)
                     /locus_tag="VQ540_001773"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HET2545536.1"
                     /translation="MIITIPIKNQKDIGTPSDSVVVLGYFDGIHKGHQELFRVANKAA
                     RKDLLPIVVMTFNESPKIALEPYHPDLFLHILNPAERERKLKREGVEELYLLDFSSQF
                     ASLTAQEFFATYIKAMNAKIIVAGFDYTFGSDKKTAEDLKDYFDGEVIIVPPVEDEKG
                     KISSTRIRQAILDGNVKEAGKLLGAPLPSRGMVVHGNARGRTIGYPTANLVLLDRTYM
                     PADGVYVVDVEIQRQKYRAMASVGKNVTFDGEEARFEVNIFDFNQDIYGETVMVYWLD
                     RIRDMTKFDSVDQLVDQLKADEEVTRNWS"
     gene            7879..8084
                     /locus_tag="VQ540_001774"
                     /pseudo
     CDS             7879..8084
                     /locus_tag="VQ540_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844775.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
     gene            complement(8395..8688)
                     /gene="rpmA"
                     /locus_tag="VQ540_001775"
     CDS             complement(8395..8688)
                     /gene="rpmA"
                     /locus_tag="VQ540_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HET2545537.1"
                     /translation="MLKMTLNNLQLFAHKKGGGSTSNGRDSQAKRLGAKAADGQTVTG
                     GSILYRQRGTHIYPGVNVGRGGDDTLFAKVEGVVRFERKGRDKKQVSVYPIAK"
     gene            complement(8705..9049)
                     /locus_tag="VQ540_001776"
     CDS             complement(8705..9049)
                     /locus_tag="VQ540_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HET2545538.1"
                     /translation="MIQAVFERAEDGELRGAEITGHAESGEYGLDVVCASVSTLAINF
                     INSIEKFAGYEPILELNEDEGGYLMVEIPKDLPSHQREMTQLFFESFFLGMANLSENY
                     SEFVQTRVITEN"
     gene            complement(9065..9379)
                     /gene="rplU"
                     /locus_tag="VQ540_001777"
     CDS             complement(9065..9379)
                     /gene="rplU"
                     /locus_tag="VQ540_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HET2545539.1"
                     /translation="MSTYAIIKTGGKQVKVEVGQAVYIEKLNVEAGQEVTFNEVVLVG
                     GENTVVGTPLVAGATVVGTVEKQGKQKKVVTYKYKPKKGSHRKQGHRQPYTKVVINAI
                     NA"
     misc_feature    complement(9415..9502)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            complement(9597..10196)
                     /locus_tag="VQ540_001778"
     CDS             complement(9597..10196)
                     /locus_tag="VQ540_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HET2545540.1"
                     /translation="MTFCAGYVDAYTFIVRGNTLVAGQAGNVVFLSVELIQNNVSDVR
                     DKLLTLITFIMGVFLLTIYKEKLRIVKKPILSLIPLAILSIIIGFVPQTVDNIYLVQP
                     LAFCMGLVTTAFGEVSGIAYNNAFMTGNIKRTMLAFGDYFRTKHTPFLREGFIFVSLL
                     SSFVLGDVFSAYLTIFYHEKTILGVPIMMSIFYLSMLFA"
     gene            10666..10965
                     /locus_tag="VQ540_001779"
     CDS             10666..10965
                     /locus_tag="VQ540_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HET2545541.1"
                     /translation="MMNMQNMMRQAQKLQKQMEQSQAELAAMQFVGKSAQDLVQATLT
                     GDKKVVSIDFNPAVVDPEDLETLSDMTVQAINSALEQIDETTKKKLGAFAGKLPF"
BASE COUNT         3535 a         2316 c         1863 g         3473 t
ORIGIN      
        1 aaaatcgtca taaacaattc acaaactaaa tttccagaaa aggaaagaaa agttggaagt
       61 ggtaatccca tcataaaaac tccgacacct gtcaaagcca gtaaaatcaa aagattataa
      121 atattagctt taattttact agctagaaga gccccaatga tggaaccaat agcccccata
      181 gttaaaatac ttgcataggc tccttctgac ccgtaaagct gattcgaaaa gggaagtaga
      241 aattcaaaag ctgcaaaaaa gaaattaacg ctggaagcta ccagcaaaag gaagaaaatt
      301 tcttgctgat gccagatata gtgtaaccca tccttgatat ctacaaaaat atctctccca
      361 gtaaaagcct ttttctcttg aacttttgct tcctcttttg gaaggaaagt cactagaata
      421 aaagcaatga aaaaagtcag cgagtctagc agtagcgtca tatggagact tgcaaactgt
      481 aaaacaagga aggaaagaac aggagagcta acacctacaa cctgcaaaac cagctctaag
      541 cgagaattat agatcacaat ctcatctttc tccaccactt cagttatgat agctttattg
      601 gctgtgcgag aaaaggcaaa agcaataacc tgcacaatgt tagcaacaat caaagcgcca
      661 atcatccagc tatcattcct tatgaaagaa atagccagac aaagaatccc acaaacaaga
      721 tctgccgtca ttaaaatctt acgacgagaa aaacggtctg aaataactcc gccaaaggga
      781 ttgacgagaa tagatgtgac gagctcagaa atctgataca ttcctaaaac tgtctgtcct
      841 atagtcccca tagaagccaa ccagacacta tttccataat catagagcat atttcccatt
      901 ttattgatag ccccacggct aatcaactgc actgcatagc gattcatatt aaagctcctc
      961 tcaaattttg aaactattgt atcaaaaccg aaaggagctt tttatttttt cccttatttg
     1021 ggaaaattaa cttttgacaa atttttcgta gtgttcctga taataggcta cttgctctgg
     1081 aagacctaac acatcaaaaa tatgcatggc ctcttgcatc tgcttacagc cttctttaca
     1141 ctgtcctttt tgatataagg caaaaccttt taaataatgg aaaacattac gctcataaag
     1201 cttaatacct ttgtcaataa tcttctctgt ataagcctca aaatagttgg cattataaaa
     1261 agaagaatgc tctaaacaat gctggtaaca attgagggcc aaaatcaaca ctaatctctt
     1321 atggcgacta atctcttggt aaaattcctc cctctccata acttctctac caatccgagt
     1381 gacatagtct acatcgtaga aactatagag gttaccgaaa agaatcaact catacatggt
     1441 ccattcttct gttttgaaga gataatctgc taccttatcc aaatcatcct gcttcatatc
     1501 ataactcgca tctctttgac aaatcagacc ttgtagcaaa atccagttca gctcaaaata
     1561 aagggaagtc gtcgaactct tagacttttc aagttgttct ctttgaagct tttgaaaacc
     1621 tgcaatatcg tttgaatagt aaagtgggat aatctgtgcc atcatagaca catgttcatg
     1681 attatgaaaa ttccttgcct tatccatgaa attttcgatt gttacatgaa tgttatccaa
     1741 aatctcaaag aaacgggaga ctgccaggtc agactcccca agctcaaagc gagataactg
     1801 agaggtagag caggattcgc ctgctgcttc ctttaaagaa taatttccac ttgttcgaaa
     1861 ttcacgaaat acttttccaa gatgttccat ctttacacct gatctgataa ttcttcccac
     1921 tcaagcatag cttcttcctg acgatggctg attttatcca gctcagcctg taattccatg
     1981 agtttgtcgg catcgtttgt ttccaacatt tgttcagaaa tggcttggct ttgactttct
     2041 agctcttcaa tttcagcttc tagactttcg atttgtcgca tgagtttgcg aacttctttt
     2101 tgactttctt tctgggcctg atagtcattg actggacttg cttcctttgc ttgattgcta
     2161 gttgaagctt cctcagtctg actcatttct gctgttgctt tcttctcaac atagtagtcg
     2221 taatctccaa ggtagagagt tgaaccattc tcagacaatt ccaaaacatg agttgccaca
     2281 caattgataa agtaacgatc atgactgaca aaaagcaagg taccatcaaa gtcaatcaag
     2341 gcattttcta gcacttcctt actatcaata tccaagtggt tggtcggctc atccagaatc
     2401 aaaaagttat tgttttccat agacaattta gctaaaagca aacgagcttt ttcgccacca
     2461 gatagcatgc cgactgattt tttaacatca tctcctgaga aaaggaaggc tccaagacgg
     2521 ttgcggattt caacttctgg tgtcaatttg aaatcattcc agagttcatc cagcaccgta
     2581 ttacttggtg tcagcttgct ttgggtttgg tcatagtaac caacctcaac attagcgcca
     2641 aagcgctttt ctcccttgat aaacggaatt tgatccacga ttgatttgat aaaggttgat
     2701 tttccgatac cattgggacc aacgatagca acagcattca tcttacgaag gtctaggtta
     2761 atcggttgtg acaggacttc cccatcatag ccaacagccg cattttcaac agtcaaaaca
     2821 acattgcccg acgttttttc agactggaag gtcatgttgg ctgctttctt gccagcttcc
     2881 ggcttgtcca aacgctccat tttttctagt tgtttacggc gagattgagc acgtttggtc
     2941 gttgaagcac gaactagatt gcgattgaca aagtcttcca gagcagcgat ttccttctgt
     3001 tgcttttcat agttttttgc ctcagtagct agcttttgct ccttcaactc gacaaaacga
     3061 gagtaattcc ccacatagcg atccaaggaa tgcttggtca aatctagcgt aattgtcgca
     3121 accttgtcca agaaataacg gtcgtggctg acgataatga gggcaccgct atagtttacc
     3181 aagtaattct ctagccagga gatggtttca atatccaagt ggttagttgg ctcgtccaag
     3241 accaagagat tgggcttttc aaggagcatt ttagctagag ccaaacgagt attttgacca
     3301 cctgaaagtt cagctatttt catctgccac atagactcgt caaacttgaa tccattcaaa
     3361 atcgctcgaa tatcagcttc ataggtaaag ccacctgctt ggcgaaaatt ctcagataag
     3421 cggtcataat ctgacatcag tttatccaaa tcctcaccag acttttcacc catctccagc
     3481 tccatctgac gcagttgtct ctccgtccga cgcaaatcat taaagacatg aagcatttca
     3541 tcgtagatgg tattttcaga ctcaaaacgg ctatcttggg ctaggtaaga cagagaaata
     3601 tcttttttct tattgatttc tccgctagtt ggctcctctt ctccaactaa aatcttcaaa
     3661 agagtagact tacctgcacc atttttccca acaagagcaa tccgatctcg ttcatcaacc
     3721 tgcaggttga tattatcgaa aagaacctct cctgcaaaag aacgttcaat tttattagct
     3781 tgtaaaataa tcataagagt agtatagcat gtttccctaa ggcattcaag ataatcgtaa
     3841 gtcttttagt acaactttta taacataaaa taaactaaat tatgtatatt ttatattaga
     3901 ttccttcact atcttgttgg attttctaac cagctaatct tgtttcaaat agttatcgca
     3961 caagcctatt atttaattct tttcattatt tacgtacgcg tatagcagat tgaaataaga
     4021 tgagaacaaa tcgattggga aagtaaaatt aatttctata aatgttttag caattgtttc
     4081 gtactatttt agattcagtc tactatgtac aatattttcg gaacattcaa ctttttaact
     4141 ctatttatta ctagatttca taattaaaaa gcctactgac caagctagaa agcttgatac
     4201 aataggcttt ttaaagactg attatttaac agcgtcttta agagctttac cagctttgaa
     4261 tgctggtact ttagaagctg caattgtcat ttctttacca gtttgtgggt tgcgaccttt
     4321 acgttctgca cgctcacgaa cttcaaagtt accaaaaccg atcaattgaa ctttttcacc
     4381 agctgcaaga tagtcagcta ctgctgcaaa tacagcttca actgctgctg ctgagtcttt
     4441 cttagtcaat tctgtagctt ctgctacttt agcgatcaaa tcttgtttgt ttgccatgtt
     4501 aatgattcct ccagataatt tctaattaac aaatataatc atatcctaaa atccctttta
     4561 ggtcaagtta aaaacgctat ttcttccaat tttatttatt ttttaggagt ggtaacgtat
     4621 caaaatagcc caagcgttct cacccgtgtg agtttgaata atggaacccg tttccaaaac
     4681 agaaattggc ttttcaacat aagcttgtaa gctttctttc atctcttttg cccaatcatc
     4741 actaccagaa tatgaaattc caatctctgc tacagcacgt tcagaaagcg atgttatcaa
     4801 ctcatctaac cattttttaa atgttttagt tccacgacct ttaaccattg gctgcaattc
     4861 atggtctttc atttgcatga caacacggat attgagaagg gagctcaaca agccagttac
     4921 acggccaatt cgtccacctt tgacaagatt ttccaaagtt gaaacaccaa tataaagctc
     4981 tgtatggttt ttaacctctt ctacatgaga taaaattgcc tccatatctt taccttcttg
     5041 agctaacttc gcagcctcaa caacttggaa tttcagggct tggtcagtga aggaactatc
     5101 aacaacaatc acatctgcag tagataggct agcaccttgg cgtgctgctt ctaccgtacc
     5161 cgaaagagca tgggacatat gaatagcaag aatctggcca ccatctttgc ataggtcttc
     5221 aaaaatctca gcaaagacac ctacaggtgg ctgacttgtt ttcggaagat tcttactttc
     5281 ttgcatcaac tgaagaaatt taccttcttc tttcaaatcc gcatcagaat aaacaacatt
     5341 atcaatcatt acagataatg gaacaattgt aatatctaat tgctttacta gttcaggttc
     5401 aatagtaaca gatgaatcgg ttacaatctt aatttttgtc atagtatcaa tctttctatt
     5461 ttaggattca gattggtttc cttacttcta attatatcaa aaaaaagatt aaaaatccta
     5521 atggagtcaa tcaaattttc cgtaaaattt gatataatca acttataaga aaagaggtgt
     5581 cctatgatta aaaaaattta ccccattttt accattttac taggtgctgc tatttatgct
     5641 tttggactga cttattttgt agttccccat catctctttg aaggaggggc gacaggtatt
     5701 accctcatca cattttatct ttttaaaatc cctgtttccc tcatgaacct gctgattaat
     5761 attccccttt tcatcctagc ttggaagatc tttggagcca aatccctcta ttctagttta
     5821 ctaggaacct tagctttgtc cggctggtta gctttttttg agcatattcc ccttcatatt
     5881 gatcttcaag gtgatttact aataacagcc cttatagcgg gaatcctatt gggaattggc
     5941 cttggaatta tttttaatgc tggaggtaca actggcggaa ctgatattct agctcgtatt
     6001 ctcaacaaat acactcatat atccatagga aaactgctct ttatcttaga tttttgtatt
     6061 ctcatgttga ttctcctaat cttcaaggat ttgagattgg tttcctacac gcttttgttt
     6121 gattttattg tttctcgtgt tattgatttg attggtgaag gaggatatgc cggcaaaggc
     6181 tttatgatta tcacaaaacg tcctgaccaa cttgctaagg cgattaatga tgacctcgga
     6241 agaggtgtta cttttatttc tggtcaaggc tactatagta aagaaaattt gaaaatcatc
     6301 tactgtattg tcggaagaaa tgaaattgtg aaaacgaagg aaatgattca tcgaatcgat
     6361 cctcaagcct ttataactat tacagaagcc catgaaatcc taggagaagg cttcaccttt
     6421 gaaaaagaat aaaaagaggt aatgtcgtga cctcaaaagt tagactaaat catctatctt
     6481 ttgggttaca gacaacctct tttttgtttt atttactcaa gctcttaaga ccaattccga
     6541 gttacttctt catcagcctt taactgatcc actaattggt caactgagtc aaatttggtc
     6601 atatcacgaa tgcgatcaag ccaataaacc atgacggttt ccccataaat atcttgatta
     6661 aaatcaaaaa tattgacttc aaaacgtgct tcttctccat caaaggtcac atttttcccg
     6721 acactagcca tagcacgata cttctgtctt tgaatctcaa catcaacgac ataaacgcca
     6781 tctgctggca tataagtacg gtctaaaagc actaaattcg ctgtcggata accaattgta
     6841 cgaccacgag cattaccatg aaccaccata cctcttgatg gaagcggtgc ccccaaaagt
     6901 tttcctgctt ctttcacatt tccatctaaa atagcttgac ggatacgagt tgaactaatc
     6961 tttcctttct catcttctac aggtggaaca atgataactt ctccatcaaa gtaatccttt
     7021 aaatcttctg ctgttttttt gtcagaacca aatgtataat caaaacctgc aacaataatt
     7081 ttggcattca tagccttgat ataagttgca aagaattctt gtgcagtgag actagcgaat
     7141 tgactactaa aatcaaggag atataattct tctacacctt cgcgctttaa ttttctttca
     7201 cgttcagcag ggttcaaaat atgcaaaaac aaatccggat gataaggctc taaagcgatc
     7261 tttggagatt cattaaaggt cataacgacg ataggtaata aatcctttct cgcagccttg
     7321 ttggcaacac gaaataattc ttgatgcccc ttatgtatgc catcaaaata gccgagaaca
     7381 acgactgaat cagatggtgt gccaatatct ttttggtttt ttataggaat agtaataatc
     7441 ataaaataat tatatcatag cgatagctat ttctggaaca gaaaatctga aatgttgttt
     7501 ttttcacatg aagtgtacct gttttcaaaa agcactttat tctatcgttg cttaactatg
     7561 aactttgcaa tattcttctc aaaaacttgt aggacatctt caaaattttg caaggagtga
     7621 ttagacttgt tcggtaacca taaagtgtca tactatgtta tgtatgaaaa agcaatgcaa
     7681 ctaactcctg agaactttaa attactaatt ggtgccgaaa aggtagaatt tagaatcgag
     7741 gtacacctat ggctgtaaaa tttacaaaat gagacaactt gggcaagatg tttgaagaat
     7801 ttcctaaact ccctgatttg aagcaagtca ctttccctga tgacaaagaa aaaagccaaa
     7861 acagcaaaga aaaactagat gactgctttc caacaactcc catctagtgt gcttcagact
     7921 gggctatttt tctctccatc tgttagcttg gattctcaga ccgtttcagc taaagaatat
     7981 cttttccctt atcagaagga acggctcaaa ccattcagac aagtgaaggg acgacaagcc
     8041 aatatttgaa accagatagc agttcttata gtcaattgaa ataaaatctg aagaaatcga
     8101 gtaggaaact catatcaatt tttaacagtg ttctattcca gattcatact caatgaaaat
     8161 taaagtgcaa actaggaagt tagccgcagg ctgtacttga gtacggcaag gtgaaactga
     8221 cgtggtttga atttgatttt cgaagagtat caatccacta tacatattaa aaagtatgga
     8281 tatcaaaaca aaaaaacagg ctctccgaaa actcggaaag ccttatttta agctgtttct
     8341 agcttcctca cctttacatt tcaaggttcg ggataaaagg ttcaatggac ctttttattt
     8401 agcgattggg taaacagaaa cttgtttttt atcgcgtcct ttacgttcaa agcgtactac
     8461 gccttcaact ttagcgaaca aagtatcgtc tccaccacga ccaacgttta cacctggata
     8521 gatgtgtgta ccacgttgac ggtaaaggat tgatccacct gttacagttt gtccgtcagc
     8581 tgctttagct ccaagacgtt ttgcttgtga atcacgtccg tttgatgtag aacctccacc
     8641 ttttttgtgg gcgaaaagtt gcaagttgtt aagagtcatt tttaacataa tgttttcctc
     8701 cgtgttagtt ttctgtgata actctggttt ggacgaactc agaatagttc tccgataagt
     8761 ttgccatacc taagaaaaat gattcaaaga ataactgggt catttctctc tggtgtgaag
     8821 gaagatcttt tggtatttca accatcagat agccaccttc atcttcgttt aattctagga
     8881 ttggttcata gcctgcaaat ttctcaatag aattgataaa gttaatggca agcgtagaaa
     8941 ccgatgcaca cacgacatct aagccgtatt cgccactctc ggcgtgtcca gtaatttccg
     9001 cacccctcag ctcgccatct tcggctctct caaagactgc ttgtatcatg tgttctcctt
     9061 aaaattaagc gttaattgcg ttgatgacaa cttttgtata tggttgacgg tgaccttgtt
     9121 tacggtggct acctttttta ggtttgtact tgtaagtaac aactttcttt tgttttcctt
     9181 gtttttcaac agttccaact acagtagctc cagcaacaag tggagttccg acaacagtgt
     9241 tttcaccacc aacaagaaca acttcgttaa aagtaacttc ttgaccagct tcaacgttca
     9301 atttttcaat gtaaactgct tgaccaactt caactttaac ttgttttccg ccagttttga
     9361 taattgcgta tgtgctcatt atgcacctcc tatgattttt atgggtttcc ccgatttttt
     9421 gtgaagactc gcctagcatc gtgggacaaa ccacttaaac ttgaataatc aagcaacgat
     9481 gttcgtgcgg ttgcacagga tcgtgcatag tcaactcttc aagtatagca tatctcctat
     9541 tttcttacaa gtaataacac ctaaaatcaa gctttttctt ttactttttt ctgccactag
     9601 gcaaaaagca tactgagata aaaaatgctc atcataatag gaacaccaag aatggtcttt
     9661 tcatgataga aaatcgtcaa ataggctgaa aagacatcgc caaggacaaa actactaagc
     9721 aggctaacaa atatgaaccc ttcacgcaaa aaaggagtgt gcttagttcg gaaataatct
     9781 ccaaaagcta gcattgttcg tttgatattc cctgtcataa aggcattatt gtaggcaata
     9841 cccgaaacct caccaaaagc agttgtcacc agtcccatac agaaggccaa gggctgcact
     9901 agatagatat tatctacagt ttgtggcaca aaaccaataa ttattgatag gattgctaaa
     9961 ggaatcaagg acagaatagg ttttttcaca attctcaatt tttccttata aatcgttaat
    10021 aaaaagactc ccattataaa cgttattaag gttaaaagct tatccctaac atccgaaaca
    10081 ttattttgta ttagctctac cgaaagaaag acaacatttc cagcttgtcc agctacaagg
    10141 gtattccctc gaacaataaa agtgtaagca tccacatatc cagcacaaaa tgtcaaaaaa
    10201 gtgctaacct tttagactga cgtgatattt ttcttatagg taataacctc attttccctc
    10261 ccattgtatt ttctcttaga aatattgtac catttctttc taaaaaatcg tagactacca
    10321 tttagatttt actattagca taaaaataat aatagacaac tatttatcca aaaatagata
    10381 gaggtaacat gtttgcaaac aaagcatacg aacctttagt aaaatcattt ccatgaaact
    10441 agaatagagc ccctcttagc aaaaatcatt attttaattt atttctaatc actccttgac
    10501 ataaataact ctcaccaata aaagactatg tcttaaaaaa atggtataat aaaatcaata
    10561 cctgggcttg atggctatgc tactaataac aattaggaga gaaaatcagg cacttgttaa
    10621 caacaaggat tatccccttg agatgaaagg aactttagaa atcttatgat gaacatgcaa
    10681 aacatgatgc gtcaagcaca aaaacttcaa aaacaaatgg aacaaagcca agctgaactt
    10741 gctgctatgc aatttgttgg caaatctgct caagatcttg tccaagcgac cttaactggc
    10801 gataagaaag ttgtcagcat tgatttcaat ccagctgtcg ttgacccaga ggaccttgag
    10861 actctttctg atatgaccgt tcaagccatc aactctgctc ttgaacaaat cgatgaaact
    10921 actaagaaaa aactgggtgc tttcgctggg aaattgccat tctaaaaaca aggagctaga
    10981 acaatacttg tcgataacaa aggctaagaa aggtgcaaaa attataaaaa acgcatagta
    11041 tcaagcaacc taaaactttg ggctctataa tatttgtagt gggtaaatcc actatagata
    11101 ttatggagcc tattttattg tagaaaaaaa tcccataaga tctataatga aaagcgacca
    11161 aacaactcat tagaaagatt catatgg
//
LOCUS       DAVBDR010000062        11099 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.062, whole genome shotgun sequence.
ACCESSION   DAVBDR010000062 DAVBDR010000000
VERSION     DAVBDR010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11099)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11099)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11099
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.062"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            1..530
                     /locus_tag="VQ540_001780"
                     /pseudo
     CDS             1..530
                     /locus_tag="VQ540_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(646..1449)
                     /locus_tag="VQ540_001781"
     CDS             complement(646..1449)
                     /locus_tag="VQ540_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic/DOC family protein"
                     /protein_id="HET2545542.1"
                     /translation="MQSTYNIDNPNLSYEAKRDLWRIGFGLQKVDNLVPSAYMESLAE
                     KQSRGELTYEQVYEDATAYHHTIDASTEEADLVSLRIVELLSRRGFSFSPATLLAIHK
                     ELFQDIFEPSIPVGQFRQTNITKNEPVLNGESVVYSDYSMIQMTLDYDFNQEKQVAYA
                     TLTQADVVKQIQHFISGIWQIHPFREGNTRTVTVFLIQYLREFGFDIDNTPFQQHSKY
                     FRDALVLDNAKILQRRSEFLTAFFENLLLGGQNDLSSEKMYLDLDLDFS"
     gene            complement(1728..2483)
                     /locus_tag="VQ540_001782"
     CDS             complement(1728..2483)
                     /locus_tag="VQ540_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3883 domain-containing protein"
                     /protein_id="HET2545543.1"
                     /translation="MSKHPHYELLNLIGYGLAKFDKLFIKEFQCSSKSEFYRYVVSLG
                     IAETTGVVKNRMDLFDPYFDNNRKGWWQKAEVYRFRKDLIDMMFGNEDVHSYAEIVKM
                     LLASEGKKTGITIVEKPIVRTKFKRLQETGMEAENYFILHFDKEEKFQGGQLTDARLY
                     GDGYDFQVDVQEYSYLAEVKGIRKSKGRVRLTAKEFEKVKEFQSDFILSLVTNLDDIP
                     KLVLIDNPLKHFEFKKNIIKNEIIEYRSVEDLY"
     gene            complement(2553..5204)
                     /locus_tag="VQ540_001783"
     CDS             complement(2553..5204)
                     /locus_tag="VQ540_001783"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009732359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HET2545544.1"
                     /translation="MSKELSSKYNPAEVEAGRYQKWLDADVFKPSGDQKAKPYSIVIP
                     PPNVTGKLHLGHAWDTTLQDIIIRQKRMQGFDTLWLPGMDHAGIATQAKVEERLRGEG
                     ISRYDLGRESFLTKVWEWKDEYSTTIKEQWGKMGLSVDYSRERFTLDEGLSKAVRKVF
                     VDLYKKGWIYRGEFIINWDPAARTALSDIEVIHKDVEGAFYHMNYMLEDGSRALEVAT
                     TRPETMFGDVAVAVNPEDPRYKDLIGKNVILPIANKLIPIVGDEHADPKFGTGVVKIT
                     PAHDPNDFLVGQRHNLPQVNVMNDDGTMNELAFEFSGMDRFEARKAVVAKLEEIGALV
                     KIEKRVHSVGHSERTGVVVEPRLSTQWFVKMDQLAKNAIANQDTDDKVEFYPPRFNDT
                     FLQWMENVHDWVISRQLWWGHQIPAWYNEAGEIYVGEEAPAGDGWKQDEDVLDTWFSS
                     ALWPFSTMGWPNTETTDFKRYYPNSTLVTGYDIIPFWVSRMIFQGIEFTGKSPFKNAL
                     IHGLIRDEEGRKMSKSLGNGIDPMDVIDKYGTDSLRWFLSNGSAPGQDVRFSYEKMDA
                     SWNFINKIWNISRYILMNNEGLTLDVAHDNVTKVATGEAGNVTDRWILHNLNETIAKV
                     TENFDKFEFGVAGHILYNFIWEEFANWYVELTKEVLYSDNEEEKVITRSVLLYTLDKI
                     LRLLHPIMPFVTEEIFGQISEGSIVTAEYPTVNPAFEDLAAHTGVESLKDLIRAVRNA
                     RAEVNVAPSKPITILVKTSDSDLEAFFNSNVNYIKRFTNPEHLEIASTIPAPELAMSS
                     VITGAEIFLPLVDLLNVEEELARLEKELAKWQKELDMVGKKLSNERFVANAKPEVVQK
                     ERDKQADYQAKYDATVARIDEMKKLVK"
     gene            complement(5197..5775)
                     /locus_tag="VQ540_001784"
     CDS             complement(5197..5775)
                     /locus_tag="VQ540_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000550018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HET2545545.1"
                     /translation="MHLFIIGAPASGKMTIGQELSRLTDATLFYNHQAIDFALEIYQD
                     YTEEMWEFVRGITFSFLGASARNQRSVILTDVIDFSNQYQLMYLKQIQNLLDDYHQEI
                     LFVELETSLEECIRRNRTENRLKHKPLKRHIEVSEREILETAETLQLNSQYQPNELHH
                     YFKINNTNLSAEEAAKQIQNKINKIEKGHTHV"
     gene            complement(5775..6245)
                     /locus_tag="VQ540_001785"
     CDS             complement(5775..6245)
                     /locus_tag="VQ540_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000124546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2545546.1"
                     /translation="MARTELPDKIETERLVLRVRTVADAEDIFDYASLPEVAYPAGYG
                     IVVKGTDKIVGSVDFNHRHEDDVLEIGYTLHPDYWGRGYVPEAARALIDLAFKDLGLH
                     KIELTCFGYNLQSQRVAEKLGFTLEARIRDRKDAQGNCCDDLRYALLKSEWEVI"
     gene            complement(6232..6810)
                     /locus_tag="VQ540_001786"
     CDS             complement(6232..6810)
                     /locus_tag="VQ540_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HET2545547.1"
                     /translation="MKQSFKTNKLYYGFPVFILGYQDQNFGYNITTCSSSYSLGDWVV
                     IGVVARENAAEQIKQYQKFTVNISDETSMLAMEQAGFISHQEKLERLGVHYEISERTQ
                     TPILDACPLVLDCRVDRIVEEDGICHIFAKILERLVAPELLDEKGHFKNQLFAPTYFM
                     GDGYQRVYRYLDKRVDMKGSFIKKARKKDGKN"
     gene            complement(7093..7488)
                     /locus_tag="VQ540_001787"
     CDS             complement(7093..7488)
                     /locus_tag="VQ540_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HET2545548.1"
                     /translation="MSKKLNRKKQLRNGLRRAGAFSSTVTKVVDETKKVVKRAEQSAS
                     AAGKAVSKKVEQAVEATKEQAQKVANSVEDFAANLGGLPLDRAKTFYDEGIKSASDFK
                     NWTEKELLALKGIGPATIKKLKENGIKFK"
     gene            complement(7584..7838)
                     /locus_tag="VQ540_001788"
     CDS             complement(7584..7838)
                     /locus_tag="VQ540_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1912 family protein"
                     /protein_id="HET2545549.1"
                     /translation="MSYEQEFMKEFEAWVNTQIMINDMAHKESQKVYEEDQDERAKDA
                     MIRYESRLDAYQFLLGKFENFKVGKGFHDLPEGLFGERNY"
     gene            complement(7847..9181)
                     /locus_tag="VQ540_001789"
     CDS             complement(7847..9181)
                     /locus_tag="VQ540_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000752887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF438 domain-containing protein"
                     /protein_id="HET2545550.1"
                     /translation="MTDEWIHILRDILLELHNGASPESVQDRFDATFTGVSAIEISLM
                     EHELMNSDSGVTFEDVMELCDVHANLFKNAIKGVEVLDTEHPGHPVRVFKEENLALRA
                     ALIRIRRLLDTYELMEDEEMLAEMRKGLVRQMGLVGQFDIHYQRKEELFFPIMERYGH
                     DSPPKVMWGVDDQIRELFQTALTTVKSLPEVSISSVKEAFEAFATEFESMIFKEESIL
                     LMILLESFTQDDWLQIAEESDAYGYAIIRPSEKWVPERQSFIEEKIAEEPVQLDTAEG
                     QVQQVIDTPEGHFTITFTPKEKEAVLDRHSQQAFGNGYLSVEQANLILNHLPMEITFV
                     NKEDIFQYYNDNTPADEMIFKRTPSQVGRNVELCHPPKYLDKVKTIMKRLREGSKDKY
                     EMWFKSESRGKFVHITYAAVHDEDGEFQGVLEYVQDIQPYREIDTDYFRGLE"
     gene            complement(9181..9414)
                     /locus_tag="VQ540_001790"
     CDS             complement(9181..9414)
                     /locus_tag="VQ540_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006144975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1858 domain-containing protein"
                     /protein_id="HET2545551.1"
                     /translation="MDNIIDVSIPVAEVVDKHPEVLEILVELGFKPLANPLMRNTVGR
                     KVSLKQGSKLTGTPMDKIVRTLEANGYEVIGLD"
     gene            9445..9519
                     /locus_tag="VQ540_001791"
                     /pseudo
     CDS             9445..9519
                     /locus_tag="VQ540_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829418.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            9508..9633
                     /locus_tag="VQ540_001792"
     CDS             9508..9633
                     /locus_tag="VQ540_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004238277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysyl-tRNA synthetase"
                     /protein_id="HET2545552.1"
                     /translation="MDRTDEVSNHTYSKVKLTWFEEIFEEYKMILLLILYHMERD"
     gene            complement(9683..9823)
                     /locus_tag="VQ540_001793"
     CDS             complement(9683..9823)
                     /locus_tag="VQ540_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000668195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2545553.1"
                     /translation="MKFFWTILAILFIKPIIGIVKFFWMIISFAVQLLFYKILDWFFK
                     LI"
     gene            complement(9820..10002)
                     /locus_tag="VQ540_001794"
     CDS             complement(9820..10002)
                     /locus_tag="VQ540_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2545554.1"
                     /translation="MNPIKAFAKIYGNYFLTVQGVKVMKTIKKDDHVVVGLGKLFIAD
                     KLMDTARWLIKPEERE"
     gene            complement(10004..10787)
                     /locus_tag="VQ540_001795"
                     /pseudo
     CDS             complement(10004..10787)
                     /locus_tag="VQ540_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840413.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT         3249 a         2448 c         2051 g         3351 t
ORIGIN      
        1 gcagagaatc tcattcaagg ccaatttgaa ggatctaaaa caatggaaaa gtgctacaca
       61 gatgtgactg aatttgccat tccagcaagt actcaaaagc tttacttatc accagtttta
      121 gatggcttta acagcgaaat tatcgcctat aatctttcaa cttcacccaa cttagaacaa
      181 gtacaaacaa tgttggaaca ggcattcaca gagaagcact acgagaatac gattctccat
      241 agtgaccaag gctggcaata ccgacacgat tcttatcatc ggttcctaag agtaagggaa
      301 ttcaagcatc tatgtcacgc aagggaaaca gccaagacaa cggtatgatg gagtccttct
      361 ttgggattct gaaatcggaa atgttttacg gttatgagaa gtcgtttcag tcgcttaagc
      421 aattggaaca agccattata gactatattg attactacaa caataaacga attaaggtaa
      481 aactaaaagg acttagcctt gtgcaataca gaactaaatc cttcggataa attatttgtc
      541 taactttttg gggtcagtac acctaaaact ttgatgatat acgttttctt gtgagaatat
      601 ttacttcatt tttgcctaaa attcaatgtt tactcagtat ttggattatg aaaaatcgag
      661 gtctaaatct agatacattt tttctgaaga caaatcattt tgaccaccga gcaagagatt
      721 ttcaaaaaaa gctgttaaaa actcagaacg tcgctgtaaa atctttgcat tatctaatac
      781 caaggcatca cgaaaatatt tggaatgttg ctgaaatggt gtattatcaa tatcaaaacc
      841 aaactcacga agatactgaa tcaaaaagac cgttactgtc cgagtgtttc cttcgcgaaa
      901 tggatgaatc tgccagattc ctgaaataaa atgctggatt tgtttaacca catccgcctg
      961 agttagtgtc gcatatgcaa cttgtttttc ctgattaaaa tcataatcta aggtcatttg
     1021 aatcatggag taatcagagt acacaacact ttcaccattc aaaacaggtt cattctttgt
     1081 gatattggtc tgacgaaatt gccccaccgg aatagagggt tcaaatatat cttgaaacaa
     1141 ctccttatga atagcaagta aggtcgcagg actaaagcta aagcctcttc gagacaatag
     1201 ttctacaata cgtagagaaa ccaagtctgc ctcttccgta cttgcatcaa tagtatggtg
     1261 ataagccgtt gcatcctcat aaacctgctc ataagtcagt tctccccggg actgtttctc
     1321 agccaaagat tccatatacg ctgatggcac tagattgtca actttctgca gaccaaaacc
     1381 tatccgccat aaatcacgct tcgcttcata agacaagttt ggattgtcaa tgttgtaagt
     1441 tgattgcata gaaatatcct ttcaattgtt tttcttcatt accagtaaat cacgaaattg
     1501 gttggaaact ggcttaaact ataaaaagtc ctcacaatag gttctatgat atatatatat
     1561 atacttcatg taaataataa aagagttata atcagcacta ctgataaatt caataccgat
     1621 ttcgccatct taaaacttag tcaaacgaat accgttgatt tccagttcat taagtcgttg
     1681 acctgtcaag acttctcgtt ccttcaactg gaaaagttaa gggggaacta atacaaatcc
     1741 tctacgcttc tatattcaat gatttcattt ttgataatat tctttttaaa ctcaaaatgt
     1801 tttaaaggat tatcgattaa cactaacttt ggaatatcat ctagatttgt gaccaaggat
     1861 aaaataaaat ccgattgaaa ctccttgact ttttcaaatt cttttgcagt taaacgcaca
     1921 cgccccttag attttcggat accttttact tcggcaaggt aagaatactc ttggacatct
     1981 acctgaaagt catatccatc accataaaga cgggcatcgg ttaactgtcc accttggaat
     2041 ttttcttctt tatcaaaatg aaggataaaa taattctcag cctccattcc cgtttcctgt
     2101 agacgtttga atttagttcg aactattggt ttttcaacga tggttatgcc tgttttcttc
     2161 ccttcactgg caagtaacat tttaactatt tcagcataac tatgaacatc ttcatttcca
     2221 aacatcatat caattaaatc tttacgaaaa cgataaactt cagctttctg ccaccaacct
     2281 tttcgattat tgtcaaaata aggatcaaat aaatccattc tattttttac aactccagtt
     2341 gtttcagcaa ttcccagaga aaccacatag cgataaaact ccgacttgct agagcattga
     2401 aattctttta taaaaagctt gtcaaacttg gcaagaccgt agccaattaa atttaacaat
     2461 tcataatgag ggtgtttgga catcactttc tccatcaata gatattgatt tcattatacc
     2521 aaaaaacacg gctcatcacc gtgtttctgt gtttatttca ccaacttctt catctcatca
     2581 atacgtgcta cggtcgcatc atacttagct tggtaatctg cttgcttgtc gcgttctttt
     2641 tggacaactt ctggtttagc gttggcgacg aagcgttcgt tgctgagttt tttgccaacc
     2701 atgtcgagtt ctttctgcca tttggcaagt tctttttcca gacgtgccaa ttcttcttcg
     2761 acattcaaga ggtctaccag tggcaagaag atttcggctc ctgtgatgac gcttgacata
     2821 gccagttcag gtgcagggat ggttgatgcg atttccaagt gttcaggatt tgtgaaacgt
     2881 ttgatgtagt tgacattgct gttaaagaag gcttccaagt cgctatcgct tgtcttaaca
     2941 aggatagtga taggcttgct tggagcaacg tttacttccg cacgcgcatt acgaacggca
     3001 cggatcaagt ctttaaggct ttccacacca gtgtgagcag caaggtcttc aaaggctggg
     3061 ttgacagttg ggtattctgc tgtaacgata gatccttctg agatttgtcc aaagatttcc
     3121 tctgtcacaa atggcatgat tgggtgaagg agacgaagga tcttgtccaa agtgtatagt
     3181 agaacagaac gtgtgatgac tttctcttct tcgttatcgc tataaaggac ttccttggtc
     3241 aactcaacat accagttggc aaattcttcc cagatgaagt tgtaaaggat atgaccagcc
     3301 acaccaaact cgaacttatc aaagttttca gtaacttttg caatggtttc gttgagattg
     3361 tggagaatcc agcggtccgt cacattacca gcctcacctg ttgcaacttt tgtgacattg
     3421 tcatgcgcca catccagcgt caaaccttca ttgttcatga ggatatagcg agaaatgttc
     3481 caaattttgt taataaagtt ccatgaagca tccattttct cgtaagagaa acgaacgtct
     3541 tgaccaggag ctgagccgtt tgacaagaac caacgaagac tatctgtacc atatttatca
     3601 ataacatcca ttgggtcaat gccatttcca agagatttag acatcttacg tccttcttca
     3661 tcacgaatta gaccatggat aagagcattt ttaaatgggc tctttcctgt aaattcaatt
     3721 ccttggaaaa tcatgcgtga tacccagaaa ggaataatat catagcctgt tacgagtgtt
     3781 gaatttggat agtagcgttt aaagtcagta gtttcggtat taggccagcc catggttgag
     3841 aagggccaga gggcagagct gaaccaagtg tcaaggacat cttcgtcctg tttccagcca
     3901 tcgcccgctg gggcttcctc gccgacatag atttcgcctg cttcattata ccaagcaggg
     3961 atttggtgac cccaccagag ctgacgggaa atcacccagt cgtggacatt ttccatccat
     4021 tgcaggaagg tgtcgttgaa gcgcggtggg taaaattcca ccttgtcatc tgtgtcttgg
     4081 ttggcaatgg cgttcttggc caattggtcc atcttgacga accattgagt agacaagcgt
     4141 ggctcaacta cgacacctgt ccgttctgag tgaccgactg aatggacacg tttttcgatt
     4201 ttgacaaggg caccgatttc ttccaactta gcaacgactg ccttacgagc ttcaaaacga
     4261 tccatgcctg aaaattcaaa ggcaagctcg ttcatagttc cgtcgtcgtt catgacgttg
     4321 acttgtggca agttatgacg ttggccaacc aagaagtcat ttggatcgtg ggcaggtgtg
     4381 attttcacga caccagtacc aaacttagga tctgcgtgct catcaccaac gattgggatt
     4441 aatttattag caattggaag gatgacattt ttaccaatca agtccttgta gcgcgggtct
     4501 tctgggttga ccgcaaccgc aacgtcccca aacatggtct caggacgagt tgtagcaact
     4561 tcaagggcgc gtgaaccatc ttccagcatg taattcatgt gatagaaggc accttcgacg
     4621 tccttgtgaa taacctcgat atcagaaagg gctgtgcgag ctgctgggtc ccagttgatg
     4681 ataaactcac cacggtagat ccagcctttc ttgtaaaggt ccacaaagac cttacgaaca
     4741 gcttttgaca aaccttcgtc aagagtgaaa cgctcacgag agtagtctac agagagcccc
     4801 atcttgcccc attgttcctt gatagtagtg gaatattcgt ctttccattc ccagactttc
     4861 gtcaagaaag actcacgacc aaggtcatag cgggaaatgc cctcaccacg caagcgctcc
     4921 tctaccttag cctgagtggc aatccctgcg tggtccatcc caggaagcca aagggtatca
     4981 aaaccttgca tgcgtttttg acggatgata atatcttgca aagttgtatc ccaagcgtga
     5041 ccaaggtgaa gtttacctgt aacgtttggt ggtggaataa cgattgaata aggcttagcc
     5101 ttttgatcgc ctgaaggctt gaaaacatca gcatcaagcc atttttggta acgaccagcc
     5161 tcaacctcgg ctggattgta tttagatgaa agttctttag acatgtgtgt gtcctttctc
     5221 tattttgttt attttatttt gaatttgctt agcagcttct tctgcagaca aattcgtatt
     5281 atttatttta aagtagtggt gcaactcatt cggttgatat tgggaattta attgaagtgt
     5341 ttcagcggtc tctaaaattt ctctttcaga tacctcaata tgtcgtttta agggtttgtg
     5401 ctttaatcga ttctccgttc gatttcgacg tatgcactct tcaagacttg tttccaactc
     5461 aacaaaaaga atctcttgat gataatcatc caacaaattc tgaatttgct ttaaatacat
     5521 cagttgatac tgatttgaaa aatcaattac atctgttaaa attactgatc gctgatttct
     5581 tgcacttgct ccaaggaatg aaaaagtgat tccacgaaca aattcccaca tttcctctgt
     5641 atagtcctga tagatttcta gtgcaaaatc aatggcttga tggttataaa atagggtagc
     5701 atccgtcagt cgagataatt cttgaccaat ggtcattttt cctgatgctg gagcaccaat
     5761 gatgaaaaga tgcatcaaat cacctcccac tcactcttca gcaaggcata tctcaaatca
     5821 tcacagcagt tgccttgagc atctttacgg tctcttatgc gagcttcgag ggtaaagcca
     5881 agcttttccg cgactcgttg actttgaagg ttatatccaa agcaagttag ttcaatcttg
     5941 tgaagaccca aatctttaaa ggctaagtca atcaaggcac gcgcagcttc tggcacataa
     6001 cctcgccccc aatagtctgg gtgtaaggta tagccgattt ccagcacatc atcttcatgg
     6061 cgatggttga aatcgacaga gccaacgatc ttatccgttc ctttgacgac aatcccgtag
     6121 cctgctggat aggcgacctc tggcaaacta gcatagtcaa agatatcctc agcatccgcc
     6181 acagtacgga ctcgtaaaac gagacgttct gtttcgattt tatctggcag ctcagttctt
     6241 gccatccttc ttcctcgctt ttttgatgaa actgcccttc atatctacac gcttatccag
     6301 atagcgataa acgcgctgat atccatctcc catgaaatag gttggggcaa acagttgatt
     6361 tttaaaatgt cccttttcat ccaggagttc tggggcaaca agtcgctcaa gaatcttggc
     6421 aaagatgtgg caaataccgt cttcctcaac aatcctatct acccgacaat ctaaaacaag
     6481 tggacaggcg tctaaaatag gagtctgagt tcgttcagaa atttcataat gcactcccaa
     6541 acgttccaat ttctcctgat gactgataaa accagcctgc tccatcgcaa gcatagaagt
     6601 ttcatcagaa atattcacag taaatttttg atactgtttg atctgctctg cggcattctc
     6661 tctcgcaacg actccaatca caacccaatc tcctagacta tacgaggaac tacaggtcgt
     6721 gatgttatag ccaaaattct gatcttgata tcctaaaata aaaacaggaa aaccataata
     6781 tagtttatta gttttaaatg attgttttat aacaacctcc tttgactaag acacaaaaga
     6841 aaagccctgc catctacatg acagggacga atgtatttat ccgcggtacc acccaatttc
     6901 gggccaagcc cgcatcttta gtctttaaaa taaaaagaca gaaatatttc attttttcag
     6961 tcattagcaa ccagttttga cacatttgtg gacttctcag cgccgccact ttctgtaaaa
     7021 tgtgggattc aaaacacctc taatagctct attgtagcaa gtttttctcg gaaatgcaag
     7081 gctcaagaaa aattacttga acttgatgcc attttctttc aatttcttga tggtagctgg
     7141 gccgattcct ttcaaggcaa ggagttcttt ttcagtccag tttttgaaat ctgaagcaga
     7201 cttgattcct tcatcataga aagtcttggc acgatcaagt ggaagtccac ccaagtttgc
     7261 tgcaaaatct tctacagaat tagctacttt ttgagcttgc tctttggtag cttctactgc
     7321 ttgttcaact tttttagaaa cagccttacc agctgcgctt gctgactgtt ctgcacgctt
     7381 cacgactttt tttgtctcat ctacaacctt agtcacagta cttgaaaagg cacctgcgcg
     7441 acggaggcca tttcgtaatt gttttttacg attgagtttc tttgacatga taaaatcctt
     7501 tcaataaaaa atccctgctc tgacaaggat ttaacataaa cattctatca agattttagt
     7561 gaaaaatcaa gaatctttct cgtttaataa tttcgctcac caaacaagcc ttctggcaaa
     7621 tcatggaatc ccttgcctac tttgaagttt tcaaacttac caagcaagaa ctgataagca
     7681 tccaagcgac tctcgtagcg aatcatggca tctttggcac gctcgtcctg gtcttcttcg
     7741 taaacttttt gactttcctt gtgcgccatg tcgttaatca tgatttgggt attgacccaa
     7801 gcttcaaatt ccttcataaa ttcttgttcg taactcattt ttctccttat tctaatccac
     7861 gaaaatagtc cgtatcaatc tcacggtagg gctggatatc ctgaacatac tccaacactc
     7921 cttggaattc tccgtcttca tcgtgtactg cagcataggt gatgtggaca aacttacctc
     7981 gcgactcaga cttgaaccac atttcatact tgtctttgct tccctcacga agcctcttca
     8041 tgatagtttt gaccttgtcc aagtacttag gcggatggca gagttcgaca ttgcgcccga
     8101 cttgagacgg cgtccgtttg aaaatcatct catcagctgg cgtattgtca ttgtaatact
     8161 ggaaaatatc ttctttattg acaaaggtaa tctccatagg gagatgattg aggatgagat
     8221 tggcctgctc gactgaaaga tagccattac caaaagcctg ttgactatgg cggtccagca
     8281 cagcttcctt ttccttaggg gtaaaggtaa tggtaaaatg gccttctggc gtatctatga
     8341 cttgttgaac ttgaccttct gccgtatcta gctgtacagg ctcctctgca atcttttcct
     8401 caataaagct ctgtcgttct ggcacccatt tctctgacgg acggatgatg gcatagccat
     8461 aggcatcgct ctcctccgca atctgaagcc agtcatcctg agtaaaagac tcaaggagaa
     8521 tcatgaggag gatggactct tccttgaaaa tcatactttc aaactctgtc gcaaaagctt
     8581 caaaagcttc ctttacactg ctaattgaca cttctggtag tgacttgact gtcgttagag
     8641 ctgtttgaaa gagttcccta atctgatcat ccactcccca cataactttg ggaggtgaat
     8701 cgtgtccata gcgctccatg ataggaaaga agagttcttc cttacgttgg taatggatgt
     8761 caaattgccc cacaagcccc atctgacgca ccaagccctt gcgcatctcc gcaagcattt
     8821 cctcgtcttc catcaactca taggtatcta acaatctacg aatgcgaatc aaagctgcac
     8881 ggagggccaa attttcttcc ttaaagacac gaactgggtg cccagggtgt tcggtatcta
     8941 aaacttcgac acctttgata gcatttttaa aaagattggc atggacatca cagagttcca
     9001 taacatcttc aaaagtgacg cccgaatccg agttcatcag ctcgtgctcc ataagggaaa
     9061 tctcgatggc tgacacgccc gtaaaggtcg catcaaagcg atcttgaacc gactcaggag
     9121 aggcgccatt gtgcaattct aacaaaatat cccgtaggat atgaatccat tcatctgtca
     9181 ttagtctaat ccaatcactt cgtagccatt cgcttccagt gtgcgtacaa tcttgtccat
     9241 aggagttcct gttagcttag aaccctgttt aagtgatact ttacgaccaa ctgtattgcg
     9301 cattaaggga ttggcaaggg gtttaaaacc caactccact agaatttcca agacttctgg
     9361 atgcttgtcc accacttctg caacaggaat tgacacatcg atgatattgt ccatgacgac
     9421 ctccattgta tgttctaata ctcaatgaaa atcaaagagc aaactaggaa gctagccgca
     9481 ggttgctcaa aacagtgttt tgaggttgtg gatagaactg acgaagtcag taaccatacc
     9541 tacagcaagg tgaagctgac gtggtttgaa gagattttcg aagagtataa aatgatttta
     9601 ctgcttatat tataccatat ggagagagat taaaaaacta gcagtggagt tcctgctagt
     9661 tttctgcgac ttggattacc atctagataa gtttaaagaa ccaatccaat atcttgtaaa
     9721 acagcaattg aactgcaaaa gaaatgatca tccaaaagaa tttcacaatc ccaataatcg
     9781 gtttgataaa aagaatagca agaattgtcc agaaaaattt cattctctct cctctggctt
     9841 aatgagccac cgagccgtat ccattagctt atctgcaata aagagttttc ccagaccaac
     9901 aacgacatgg tcatctttct ttatcgtttt catcactttt acaccttgca cggtcaaaaa
     9961 gtaattacca taaattttag caaaagcttt gataggattc atattattct cctttgatga
    10021 tttcagcctc ttttcggatt gtttcaacat cttcttgata ttgaacttca ctatagttga
    10081 ctagcttgga taattctttc tgcaagcttt cccccattgg tttcatagtt gcaaaggtta
    10141 aaccacctga aatgatacca cccaagatag gaataaattt ccccattcct ttggccaacc
    10201 ctcccttggt aagattcaca ccaaatattt ttaagacttt tttcaaaata gggtaccaaa
    10261 gcgtctttgt taaagcttta ttaggcactg ttttcattac ctgtttggca attgttatac
    10321 caccagcacg tagcaaacaa agcagcggtt ccattcaccc ctaacattac gcctagataa
    10381 agcaagaggg tattttgagc atcttcactc aactcctcac gtgaagccca aagatcctca
    10441 taaccataaa tataacctaa ttcttgggcc aatttcagag agaaaccata aaattgagcc
    10501 acataagctg gaatggtaat tgccatagca agccctccag gtaatcctgc caaaacagaa
    10561 gtcccactcg ctaataaaac attatcccta atacaggcat tagccactcg atctaagatt
    10621 tcttgagata agagagacgt tggaccttgt tccaataagg taggaatgtc ctgtggaccc
    10681 aattctttgg aaaacttatc cactaaaaat ttcgaacgat caaccttaac aactggtagt
    10741 tttaccactt gttgtaatac ttgcatagct aagtcttgtt cagccatata caaactcctt
    10801 atttcttttt tgcaccttat catattatat ttcctacaaa aaaagcattt tctaattaga
    10861 taacattaaa aaatacagaa cccctttttt atagtaaaat aaaacaagaa caggacaaat
    10921 cgatcaggac agtcaaatcg atttctaaca atgttttaga agtagaggcg tactattcta
    10981 gtttcaatat attttaaaag aatatttttc catttcaaat tcaacctatt ttcctccacc
    11041 aaaaaagggc tctataatat ttgtagtggg taaattccct atggatatta tggagccta
//
LOCUS       DAVBDR010000063        10989 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.063, whole genome shotgun sequence.
ACCESSION   DAVBDR010000063 DAVBDR010000000
VERSION     DAVBDR010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10989)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10989)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10989
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.063"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            136..2316
                     /locus_tag="VQ540_001796"
     CDS             136..2316
                     /locus_tag="VQ540_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000974069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HET2545555.1"
                     /translation="MMKDTFKNVLSFEFWQKFGKALMVVIAVMPAAGLMISIGKSIVM
                     INPTFTPLVITGGILEQIGWGVIGNLHILFALAIGGSWAKERAGGAFAAGLAFILINR
                     ITGTIFGVSGDMLKNPDAMVTTFFGGSIKVADYFISVLEAPALNMGVFVGIISGFVGA
                     TAYNKYYNFRKLPDALSFFNGKRFVPFVVILRSAIAAILLAAFWPVVQTGINNFGIWI
                     ANSQETAPILAPFLYGTLERLLLPFGLHHMLTIPMNYTALGGTYDILTGAAKGTQVFG
                     QDPLWLAWVTDLVNLKGTDTSQYQHLLDTVHPARFKVGQMIGSFGILMGVIVAIYRNV
                     DADKKHKYKGMMIATALATFLTGVTEPIEYMFMFIATPMYLVYSLVQGAAFAMADVVN
                     LRMHSFGSIEFLTRTPIAISAGIGMDIVNFVWVTVLFAVIMYFIANFMIQKFNYATPG
                     RNGNYETAEGSEETSSEVKVAAGSQAVNIINLLGGRVNIVDVDACMTRLRVTVKDADK
                     VGNAEQWKAEGAMGLVMKGQGVQAIYGPKADILKSDIQDILDSGEIIPETLPSQMTEA
                     QQNTVHFKNLTEEVYSVADGQVVGLEQVKDPVFAQKMMGDGFAVEPANGNIVSPVSGT
                     VSSIFPTKHAFGIVTEAGLEVLVHIGLDTVSLEGKPFTVHVAEGQKVAAGDLLVTADL
                     DAIRAAGRETSTVVVFTNGDAIKSVKLEKTGSLAAKTAVAKVEL"
     gene            2368..3183
                     /locus_tag="VQ540_001797"
     CDS             2368..3183
                     /locus_tag="VQ540_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HET2545556.1"
                     /translation="MKFLTLNTHSWMEKEAEEKFQILLEDILEKDYDLICFQEINQEM
                     TSSEVEVNDLYQALPAAEPIHQDHYVRLLVEKLLEQGKNYYWTWAYNHIGYDRYHEGV
                     AILSKTPIEAREILVSDVDDPTDYHTRRVALAETLVDGKELAVASVHLSWWDKGFQEE
                     WARFEAVLKKLNKPLLLAGDFNNPAGQEGYQAILASPLGLQDAFEVAQEKSGSYTVPP
                     EIDGWKGNTEPLRIDYVFTTKELAVENLHVVFDGNKSPQVSDHYGLNAMLNWK"
     gene            3323..4666
                     /locus_tag="VQ540_001798"
     CDS             3323..4666
                     /locus_tag="VQ540_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HET2545557.1"
                     /translation="MSFTKFQFKNYIREALKELKFTTPTEVQDKLIPIVLAGRDLVGE
                     SKTGSGKTHTFLLPIFQQLDEASDSVQAVITAPSRELATQIYQVARQISAHSDVEVRV
                     VNYVGGTDKARQIEKLASNQPHIVIGTPGRIYDLVKSGDLAIHKAKTFVVDEADMTLD
                     MGFLEIVDKIAGSLPKDLQFMVFSATIPQKLQPFLKKYLSNPVMEKIKTKTVISDTID
                     NWLISTKGHDKNAQIYQLTQLMQPYLAMIFVNTKTRADELHSYLTAQGLKVAKIHGDI
                     APRERKRIMNQVQNLDFEYIVATDLAARGIDIEGVSHVINDAIPQDLSFFVHRVGRTG
                     RNGLPGTAITLYQPSDDSDIRELEKLGIKFSPKMVKDGEFQDTYDRDRRANREKKQDK
                     LDIEMIGLVKKKKKKVKPGYKKKIQWAVDEKRRKTKRAENRARGRAERKAKRQTF"
     gene            5043..6233
                     /locus_tag="VQ540_001799"
     CDS             5043..6233
                     /locus_tag="VQ540_001799"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HET2545558.1"
                     /translation="MSERKLFTSESVSEGHPDKIADQISDAILDAILAKDPEAHVAAE
                     TAVYTGSVHVFGEISTNAYVDINRVVRDTIAEIGYTNTEYGFSAETVGVHPSLVEQSP
                     DIAQGVNEALEVRGNADQDPLDLIGAGDQGLMFGFAVDETEELMPLPIALSHKLVRRL
                     AELRKSGEISYLRPDAKSQVTVEYDENDRPVRVDTVVISTQHDPEATNEQIHQDVIDK
                     VIKEVIPSSYLDDKTKFFINPTGRFVIGGPQGDSGLTGRKIIVDTYGGYSRHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAAGLAKKAEVQLAYAIGVAQPVSVRIDTFGTGTVA
                     ESQLEKAARQIFDLRPAGIIQMLDLKRPIYRQTSAYGHMGRTDIDLPWERLDKVDALK
                     EAVK"
     gene            6786..7721
                     /locus_tag="VQ540_001800"
     CDS             6786..7721
                     /locus_tag="VQ540_001800"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HET2545559.1"
                     /translation="MVSTKTQIAGFEFDNCLMNAAGVACMTIEELEEVKNSAAGTFVT
                     KTATLDFRQGNPEPRYQDVPLGSINSMGLPNNGLDYYLDYLLDLQEKESNRTFFLSLV
                     GMSPEETHTILKKVQESDFRGLTELNLSCPNVPGKPQIAYDFETTDRILAEVFAYFTK
                     PLGIKLPPYFDIVHFDQAAAIFNKYPLKFVNCVNSIGNGLYIEDESVVIRPKNGFGGI
                     GGEYIKPTALANVHAFYQRLNPQIQIIGTGGVLTGRDAFEHILCGASMVQVGTTLHKE
                     GVSAFDRITNELKAIMVEKGYESLEDFRGKLRYID"
     gene            7755..8792
                     /locus_tag="VQ540_001801"
     CDS             7755..8792
                     /locus_tag="VQ540_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HET2545560.1"
                     /translation="MLAIEESQKLTLSNLPSLSLFTGTDQGQFEVMKSQVLKQIGYDS
                     ADLNFAYFDMKEVVYKDVELELVSLPFFADEKIVILDYFMDITTAKKRFLTDDELKSF
                     EEYLDNSSPTTKLIIFAEGKLDSKRRLVKLLKRDAKVFDAVEVKEQELRQYFQKWSQK
                     QGLQFTNHSFENLLIKSGFQFSEIQKNLLFLQSYKANSVIEEEDIVNAIPKTLQDNIF
                     DLTQFILTKKMDQARDLVRDLTLQGEDEIKLIAVMLGQFRTFTQVKILAESGQTESQI
                     ASSLGSYLGRNPNPYQIKFALRDSRGLSLSFLKQAISYLIETDYQIKTGLYEKGFLFE
                     KALLQIASQVN"
     gene            8965..9570
                     /locus_tag="VQ540_001802"
     CDS             8965..9570
                     /locus_tag="VQ540_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HET2545561.1"
                     /translation="MAIILPELPYAYDALEPYIDAETMHLHHDKHHQTYVNNANAALE
                     KHPEIGEDLEALLADVESIPADIRQALINNGGGHLNHALFWELMTPEKTAPSAELAAA
                     IDATFGSFEEFQAAFTAAATTRFGSGWAWLVVNKEGKLEVTSTANQDTPISEGKKPIL
                     GLDVWEHAYYVKYRNVRPDYIKAFFSVINWNKVDELYAAAK"
     gene            9726..10256
                     /locus_tag="VQ540_001803"
     CDS             9726..10256
                     /locus_tag="VQ540_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HET2545562.1"
                     /translation="MRKEIAPELYNYNKFPGPEFHLHGDKVETEGIAFSLVENIKDAF
                     DVTTFNQRFSEVLTKFDYIVGDWSNEQLRLRGFYKDDRTEEKLEKISRLQDYLLEYCS
                     YGCAYFVLENEAPKRASFDKKMRKTEEETPSRKGKKPTQTKRKSNADKKNRRRQKDQH
                     SQKEDKEQRHFVIRQK"
     gene            10277..>10989
                     /gene="rlmN"
                     /locus_tag="VQ540_001804"
     CDS             10277..>10989
                     /gene="rlmN"
                     /locus_tag="VQ540_001804"
                     /EC_number="2.1.1.192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000804770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HET2545563.1"
                     /translation="MKPSIHSLAHQTMQEWVLEQGEKKFRADQIWEWLYRKRVQSFEE
                     MTNLSKDLIAKLNDQFVVNPLKQGIVQESADGTVKYLFELPDGMLIETVLMCQHYGLS
                     VCVTTQVGCNIGCTFCASGLIKKQRDLNNGEIVAQIMLVQKYFDERGQDERISHIVVM
                     GIGEPFDNYNNVLNFFRTINDDKGMAIGARHITVSISGLAHKIRDFADEGVQVNLAVS
                     LHAPNNELRSSIMKINRAFP"
BASE COUNT         3341 a         2017 c         2395 g         3236 t
ORIGIN      
        1 tagaaatttt ttagaaaaaa gtgtaatttt tttataaaag cctttacaaa aaaaattaaa
       61 gtggtataat taaatcatag aaggtgcaaa cgttttcgta aaacgtttgc ctaaataaaa
      121 ataaaggaga tttgaatgat gaaagataca ttcaaaaatg tcttgtcttt cgaattttgg
      181 caaaaattcg gtaaggcttt gatggtagtt atcgcggtta tgccggctgc tggtttgatg
      241 atttcaatcg gtaagtctat cgtgatgatt aacccaacct ttacaccact tgtcatcaca
      301 ggtggaattc ttgagcaaat cggttggggg gttatcggta accttcacat tttgtttgcc
      361 ctagccattg gaggaagctg ggctaaagaa cgtgctggtg gtgctttcgc cgctggtctt
      421 gccttcatct tgattaaccg tatcactggt acaatttttg gtgtatcagg cgatatgttg
      481 aaaaatccag atgctatggt aactactttc tttggtggtt caatcaaagt tgctgattac
      541 tttatcagtg ttcttgaagc tccagccttg aacatggggg tattcgtagg gattatctca
      601 ggttttgtag gggcaactgc ttacaacaaa tactacaact tccgtaaact tcctgatgca
      661 ctttcattct tcaacgggaa acgtttcgta ccatttgtag ttattcttcg ttcagcaatc
      721 gctgcaattc tacttgctgc tttctggcca gtagttcaaa caggtatcaa taacttcggt
      781 atctggattg ccaactcaca agaaactgct ccaattcttg caccattctt gtatggtact
      841 ttggaacgtt tgctcttgcc atttggtctt caccacatgt tgactatccc aatgaactac
      901 acagctcttg gtggtactta tgacatttta actggtgcag ctaaaggtac tcaagtattc
      961 ggtcaagacc cactatggct tgcatgggta acagaccttg taaaccttaa aggtactgat
     1021 actagtcaat atcaacactt gttagataca gtacatccag ctcgtttcaa agttggacaa
     1081 atgatcggtt cattcggtat cttgatgggt gtgattgttg ctatctaccg taatgttgat
     1141 gctgacaaga aacataaata caaaggtatg atgattgcaa cagctcttgc aacattcttg
     1201 acaggggtta ctgaaccaat cgaatacatg ttcatgttca tcgcaacacc tatgtatctt
     1261 gtttactcac ttgttcaagg tgctgccttc gctatggctg acgtcgtaaa cctacgtatg
     1321 cactcattcg gttcaatcga gttcttgact cgtacaccta ttgcaatcag tgctggtatt
     1381 ggtatggata tcgttaactt cgtttgggta actgttctct ttgctgtaat catgtacttt
     1441 atcgcaaact tcatgattca aaaattcaac tacgcaactc cagggcgcaa cggaaactac
     1501 gaaactgctg aaggttcaga agaaaccagc agcgaagtga aagttgcagc aggctctcaa
     1561 gctgtaaaca ttatcaacct tcttggtgga cgtgtaaaca tcgttgatgt tgatgcatgt
     1621 atgactcgtc ttcgtgtaac tgttaaagat gcagataaag taggaaatgc agagcaatgg
     1681 aaagcagaag gagctatggg tcttgtgatg aaaggacaag gggttcaagc tatctacggt
     1741 ccaaaagctg acattttgaa atctgatatc caagatatcc ttgattcagg tgaaatcatt
     1801 cctgaaactc ttccaagcca aatgactgaa gcacaacaaa acactgttca cttcaaaaat
     1861 cttactgagg aagtttactc agtagcagac ggtcaagttg ttggtttgga acaagtaaag
     1921 gatccagtat ttgctcaaaa aatgatgggt gatggatttg cagtagaacc tgcaaatgga
     1981 aacattgtat ctccagtttc aggtactgtg tcaagcatct tcccaacaaa acatgctttt
     2041 ggtattgtga cggaagcagg tcttgaagta ttggttcaca ttggtttgga cacagtaagt
     2101 cttgaaggta aaccatttac agttcatgtt gctgaaggac aaaaagttgc agcaggagat
     2161 ctccttgtca cagctgactt ggatgctatc cgtgcagcag gacgtgaaac ttcaacagta
     2221 gttgtcttca caaatggtga tgcaattaaa tcagttaaat tagaaaaaac aggttctctt
     2281 gcagctaaaa cagcagttgc taaagtagaa ttgtaatata cttgaggttg gaagctgtat
     2341 tccaacctct tattttggga gaaaagaatg aaatttttaa cactcaatac tcacagttgg
     2401 atggagaaag aagcagagga aaaattccag attttgcttg aagatattct tgaaaaggac
     2461 tatgatttga tttgtttcca agaaatcaat caggagatga cctcgtcaga ggtggaggtt
     2521 aatgaccttt atcaagcttt gccagcagct gagcctattc accaagacca ttatgttaga
     2581 ctcttggttg aaaagttgtt agagcaaggg aaaaattact actggacctg ggcttataac
     2641 catatcggct atgaccgcta ccacgaaggt gtggctatct tgtctaaaac acctattgaa
     2701 gccagagaaa ttttggtttc agatgtggat gatccaacag actatcatac tcgccgtgtt
     2761 gccctagctg aaactttagt cgatggcaag gagctagcag ttgccagtgt tcatctctct
     2821 tggtgggata aaggtttcca agaagaatgg gcacgatttg aggctgtctt gaaaaaattg
     2881 aacaagccac ttttactagc tggagatttt aacaacccag caggtcagga aggttaccaa
     2941 gctattttag ctagtccatt aggcttacaa gacgcatttg aagttgctca agagaaaagt
     3001 ggtagctata ctgttccgcc tgaaattgat ggctggaaag ggaacactga accccttcga
     3061 atcgattatg tctttactac caaagagtta gcggtggaaa atttacatgt cgtatttgat
     3121 ggtaacaaga gtccacaagt gagtgatcac tatggcttga atgctatgtt aaactggaaa
     3181 taataactga aaagaggttg gaactataaa attccagcct tttcttacta gagaagctac
     3241 tggaaatagc ctaaataagt gagactactg taatggaata aaatatggta taattgataa
     3301 gatagataga atcgaggatg ttatgtcatt tacgaaattt caatttaaaa actatattag
     3361 agaagccttg aaggagttaa aatttacaac tccaacagag gtgcaagata agttgattcc
     3421 tattgttttg gcaggtcgtg acctagtagg agaatcaaaa acaggttcag gtaagactca
     3481 tactttcttg ttaccgattt tccagcaatt agatgaagct agcgatagtg tacaagcagt
     3541 gattactgca ccgagtcgtg agttggctac tcaaatttac caagtagcgc gtcagatttc
     3601 agctcactca gatgtcgaag ttcgtgtggt taattatgtg ggtggtacgg ataaggctcg
     3661 ccagattgag aaattggcaa gcaatcagcc tcatattgtt attggaacac caggccgtat
     3721 ctacgacttg gttaaatctg gtgatttagc tattcataaa gccaagacat ttgttgttga
     3781 tgaagcagat atgaccttgg atatgggatt cttggaaatt gttgataaga ttgctggcag
     3841 tcttccaaaa gacttgcaat tcatggtctt ctcagcgact atcccacaaa aactgcaacc
     3901 attcttgaaa aaatacttat caaatcctgt tatggagaaa attaagacta aaacggttat
     3961 ttctgacacc attgataatt ggttgatttc gaccaaggga catgataaga atgctcaaat
     4021 ttaccaattg actcagttga tgcagccgta tttggcaatg atttttgtta acactaaaac
     4081 gcgtgctgat gaattgcatt catatctgac tgctcaaggc ttgaaggttg caaaaatcca
     4141 tggagatatt gcccctcgtg aacgcaagcg aatcatgaat caggtgcaaa atctggattt
     4201 tgagtatatt gtcgcaacag atttagcagc gcgtgggatt gacattgaag gtgtcagcca
     4261 tgtcatcaat gatgccattc cgcaagactt atcttttttt gttcaccgtg ttggtcgtac
     4321 tggacgaaat ggcctaccag gtacagctat taccctttat cagccaagtg atgactcgga
     4381 tatccgtgag ttggagaaat tgggaatcaa gtttagtcct aagatggtca aagatgggga
     4441 atttcaagat acctatgacc gtgatcgtcg tgccaaccgt gagaaaaaac aagataaact
     4501 tgatatcgaa atgattggtt tggttaaaaa gaaaaagaaa aaagtcaaac cgggttataa
     4561 gaagaaaatt caatgggcgg ttgatgaaaa gcgccgtaaa actaagcgtg ctgaaaatcg
     4621 cgctcgcggt cgtgcagagc gtaaagctaa acgccaaaca ttttaataga aattgttgga
     4681 gtactgagct ccaacttttt tatttatgag aacgaactat ctaaaccgaa acactacatt
     4741 aaagactgca aattgcgatt aaaaatggta taatgataaa gttatatagt cccgataaga
     4801 tggtaggtat ttattacgaa gagttttcct atcagtagtt tgcaattcgc aaagaatgac
     4861 ggcttcgagg tcgctcgtct ttctacggtt gccgccatac tgcggtcacc ctatgcgcct
     4921 tactagcttc agaaataaaa aagtatcgtt tttatttctg aagctagtaa ctcttagata
     4981 atggaaattc ctatcagtac tttgtaactc tataacaata ttttttaagg ggggacattt
     5041 ttatgtcaga acgtaaatta ttcacgtctg aatctgtatc tgaggggcat ccggataaga
     5101 ttgcagacca aatttcagat gcgattttgg atgctatttt agcaaaggat ccagaggcgc
     5161 acgttgctgc tgaaacagct gtatatactg gttctgtcca cgtttttggt gaaatttcta
     5221 caaatgccta tgtggatatt aaccgtgtgg ttcgtgatac cattgcagag attggttata
     5281 ccaatacaga atatggattt tctgctgaga cggtgggagt acacccatct ttggtggaac
     5341 aatctcctga catcgctcaa ggtgttaacg aagccttgga ggttcgtgga aatgctgatc
     5401 aagatccact ggacttgatt ggagcaggtg accaagggct catgtttgga tttgcagtag
     5461 atgaaacaga agagctcatg ccattgccaa ttgcactcag tcataaattg gttcgtcgtc
     5521 tggcagaact tcgtaagtct ggagaaatta gctatctccg tccagatgca aaatcacaag
     5581 ttacagttga gtacgatgaa aatgaccgtc cggtacgtgt agatacagtc gttatttcta
     5641 ctcagcatga tccagaggcc actaatgaac aaatccatca agatgtgatt gacaaggtca
     5701 tcaaagaagt tattccatct tcttatcttg atgataagac aaaattcttt atcaatccga
     5761 caggtcgttt tgtaatcggt ggtcctcaag gggactcagg tttgactggt cgtaagatta
     5821 ttgtagatac ttatggtggc tactctcgtc atggtggtgg tgccttctct ggtaaagatg
     5881 cgactaaggt ggatcgttca gcctcttatg cggctcgcta tattgccaag aatatcgttg
     5941 cagcaggcct tgctaagaag gcagaagtgc agttggccta tgctatcggt gttgcgcaac
     6001 ctgtttctgt tcgtatcgat actttcggta caggaacagt agctgaaagt caacttgaaa
     6061 aagcggctcg tcaaatcttt gaccttcgcc ctgcagggat tatccaaatg ctggacctca
     6121 agcgtccaat ttaccgtcaa acatcggctt acggtcacat gggacgtaca gatattgatc
     6181 ttccatggga acgtttggat aaggtagatg ctttgaaaga agcagtaaaa taagatttta
     6241 agaggggaac gtcctctctt ttttatagtt tttaactata ctgggatact gttctgaaaa
     6301 tccattttgc gaaagtagag atttacatgt ataatggatt gaaactagaa tagtacacct
     6361 caacttctaa aacattgtta gaaatcgatt tgactgtcct gatcgatttc tcctgttctt
     6421 gtttcatttt actatatttc tttaaaaatg ataaaggttg agatttctcc tcgtaataga
     6481 taatcatggg gatatttcaa tccaaagttt tattcgttat cacttgacta ttgcaaggtt
     6541 ttctagagca acagagtcat ggaatggact catggttgag atttctcctt gttgcttgga
     6601 cttcattcaa aagtctgtta cccaagcctt gttcaaactt ccaatacact agctgtttcc
     6661 atagcatgac ttctgtacta gactttcttt tccgaataaa tagatagaac cacagaatct
     6721 agtaaaccta gaattaaaat tatggtataa tattagcaat aaaagaaatc tggaggatta
     6781 gaatcatggt atcaacgaaa acacaaattg ctggttttga gtttgacaat tgcttgatga
     6841 atgcagcagg tgtggcttgt atgacgatag aggagttaga agaggtcaaa aactcagcgg
     6901 caggaacctt tgttactaag acagcgacct tggacttccg tcaggggaat cctgagccac
     6961 gctaccaaga tgttccactt ggttccatca actctatggg cttgccaaat aatggcttag
     7021 actattattt ggattatctt ttagatttgc aggaaaaaga gtcgaaccga actttcttct
     7081 tatctctggt cggcatgtct ccagaggaaa cccatactat tttgaaaaaa gtccaagaga
     7141 gtgattttcg tggtctgact gagctaaatc tttcctgtcc aaatgttcca ggtaaacctc
     7201 agattgccta tgattttgag acaacagacc ggattttggc agaagtgttt gcttacttca
     7261 ccaaacctct tggaattaaa ttgccacctt attttgatat tgttcacttt gaccaagcgg
     7321 cagctatttt caacaaatat ccgctcaagt ttgtcaactg tgttaactct atcggaaacg
     7381 gcctctatat agaagacgaa tctgtcgtta ttcggcctaa gaatggtttt ggtggaattg
     7441 gtggagaata catcaaaccg actgctctag ccaatgttca cgccttttat caacgtttaa
     7501 atcctcaaat ccaaattatc ggaacaggtg gcgttctgac tggtcgagat gcctttgaac
     7561 acatcctctg tggagcaagt atggtgcagg tgggaacgac ccttcacaaa gaaggcgtca
     7621 gtgcttttga ccgcattacc aatgaactga aagcaatcat ggtggaaaaa ggctacgaga
     7681 gcttagaaga tttccgtggg aaattgcgct atattgacta aattaaatcg aaaaatctga
     7741 agaaaggaga gacgatgcta gccattgaag aaagtcagaa gttgacttta tcaaatttac
     7801 cgagcctgag cctatttaca gggacagatc agggtcagtt tgaagtgatg aagagtcaag
     7861 tgttgaaaca gattgggtat gattctgctg acctcaactt tgcctacttt gatatgaaag
     7921 aagtagttta caaggatgtg gaactggagt tggtcagcct tcctttcttt gcggatgaga
     7981 aaatcgtgat attagattat tttatggata tcacgactgc taagaaacgc tttttgacag
     8041 atgatgagct taagtcattt gaggaatacc ttgacaattc ttctccaaca accaagttga
     8101 taatctttgc agaaggaaag ctggatagca aaagacggtt agtcaaatta cttaagcgtg
     8161 atgccaaggt cttcgatgca gtagaagtaa aagaacaaga attgcgccag tatttccaaa
     8221 agtggagtca gaaacaaggt ctgcagttta ccaatcattc ttttgaaaat ctcctcatca
     8281 agtcggggtt tcaatttagc gaaatccaga aaaatcttct ctttttacag tcctataagg
     8341 cgaattctgt tattgaggaa gaggatattg ttaacgcaat tcccaagacc ttgcaggaca
     8401 atatttttga tttaactcag tttattctga ctaaaaagat ggatcaggcg cgcgatttgg
     8461 tgagagactt gaccttgcaa ggggaagatg aaatcaaact gattgcagtc atgctgggac
     8521 aatttcggac ttttactcag gtgaagattt tggcggagtc tggccaaaca gaatcgcaga
     8581 ttgcaagtag tttaggtagt tatctgggac gtaacccaaa tccttatcaa atcaagtttg
     8641 cattaagaga ttcgagagga ctttctttga gctttctgaa gcaagctatt tcctatttga
     8701 ttgagacaga ctatcagatt aagacaggtc tttatgaaaa aggtttcctt tttgaaaagg
     8761 cactcttaca gattgctagt caggtcaatt gacatttgtt gaaactacaa cccgcgtcag
     8821 gattatcttg tcgtgggttt cttgctgatt tgcttatttt attagaaagt atgtcagtga
     8881 tttccttatc tataagcaaa aaacttgaaa aaagtgaatg tttgcgttat cattttcata
     8941 tagaaagaaa aagaggtatt acagatggct attatcttac cagaacttcc atatgcatac
     9001 gacgctttgg aaccatacat cgatgcggaa acaatgcatt tgcaccatga caaacaccat
     9061 caaacttatg tcaacaatgc caatgcagct ttagaaaaac accctgaaat cggtgaagac
     9121 cttgaagcct tgcttgctga tgtagaatct atcccagctg atatccgtca agcacttatc
     9181 aacaatggtg gcggacactt gaaccacgct cttttctggg aattgatgac tcccgagaaa
     9241 acagctcctt cagcagaact ggcagcagca atcgatgcaa catttggttc atttgaagaa
     9301 ttccaagcag ccttcactgc agcagcaaca actcgttttg gttcaggttg ggcatggttg
     9361 gttgtcaaca aagaagggaa acttgaagtg acttcaacag caaaccaaga cacaccaatc
     9421 tcagaaggta aaaaaccaat cttgggcttg gacgtttggg aacatgctta ctacgtgaaa
     9481 taccgcaacg tgcgtcctga ctacatcaaa gctttctttt cagtaatcaa ctggaataaa
     9541 gtagatgaat tgtacgcagc tgctaaataa tgatagttgg agggaagaat tgttcttctc
     9601 tttttaggtt ataagattct ggtctgacaa aatcgtcaga cttttttcat ttttatgaga
     9661 aacgtgctaa ctgctagaaa ttatggtaga ataaagtatt aagtaatcgt ggaaaaagga
     9721 tatctatgcg aaaagaaatt gcacctgaat tatacaacta taacaagttt cctggtccgg
     9781 agttccattt acacggggat aaggtcgaaa cggaagggat agctttttcc ttggttgaaa
     9841 atatcaagga tgcctttgat gtgacgactt ttaatcagcg tttttcagaa gtcttaacca
     9901 agtttgatta tatcgtgggg gactggagca acgaacagct tcgcctacga ggtttttaca
     9961 aggatgaccg aacagaagaa aaacttgaaa aaatcagtcg tttacaagac taccttttag
    10021 agtattgtag ttatggttgt gcctattttg tcttagaaaa tgaagcccct aagcgagcat
    10081 catttgacaa gaaaatgcgt aagacggaag aagaaacacc ttctagaaaa ggaaagaaac
    10141 cgactcaaac taaacgaaag tcgaatgcag ataagaaaaa tagacgtcgt cagaaagacc
    10201 agcattctca gaaagaggac aaggaacaac gtcattttgt cattcgtcag aagtgagtag
    10261 agaataagga gaagaaatga aaccctcaat tcatagtttg gcacatcaaa ccatgcagga
    10321 atgggtattg gagcagggag aaaagaaatt ccgtgcagat caaatctggg aatggctcta
    10381 ccgtaaacgt gtgcagtcat ttgaagaaat gaccaacctt tccaaggatt tgattgctaa
    10441 gctcaatgac cagtttgtgg tcaatccctt gaaacaaggt attgtgcaag agtctgctga
    10501 tggtacagtc aaatatctct ttgaattgcc tgacggtatg ttaattgaga ctgtactcat
    10561 gtgtcaacac tatggtttat ctgtctgtgt gaccactcag gtcggctgta atatcggttg
    10621 taccttctgt gcctctggtt tgattaagaa gcagcgtgac ctcaataacg gtgaaatcgt
    10681 agcgcaaatc atgctggttc agaaatactt tgatgagcgt ggtcaggatg aacgcatcag
    10741 ccatatcgtt gtcatgggaa tcggtgagcc ctttgataat tacaacaatg tcttgaattt
    10801 ctttcgtact atcaatgatg ataaaggaat ggctatcggt gctcgtcaca tcacggtttc
    10861 aatctcaggt ttggctcata aaattcgtga ctttgctgat gaaggggttc aggtcaatct
    10921 tgccgtgtct cttcacgcac ccaacaatga acttcgttca agtatcatga agattaaccg
    10981 tgcctttcc
//
LOCUS       DAVBDR010000064        10760 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.064, whole genome shotgun sequence.
ACCESSION   DAVBDR010000064 DAVBDR010000000
VERSION     DAVBDR010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10760)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10760)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10760
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.064"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            104..394
                     /locus_tag="VQ540_001805"
     CDS             104..394
                     /locus_tag="VQ540_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2545564.1"
                     /translation="MELKDFTEKEQEMIKKRLTMSNISDKETTEKILALVPQDLIKRI
                     PFFVRKHATTRTIKRISIEYPELYAVAQTSGEIPEKNAKNCVRLSQLSLNKR"
     gene            418..1134
                     /locus_tag="VQ540_001806"
     CDS             418..1134
                     /locus_tag="VQ540_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HET2545565.1"
                     /translation="MKKYFIGGLGSNAYHSKDFLQELDSQVYFLNPYEKHLRDETELK
                     SWFKNEIVEEESICLIGHSIGGDLARYFASEFEEVKKLILLDGGYLDLDKILPLDTEL
                     EETKNYIKSQIISDLDVLTSKEKSEAKHWSENMEKAVRQSYHWNVEYNRYELAINYEN
                     IEAILRLRRKIQAFKREVGDTLFISPRYPNEATWREEALKELPDYFDTIFLENFGHEL
                     YTQAPKEIASLMNEWLAYFL"
     gene            complement(1263..2078)
                     /locus_tag="VQ540_001807"
     CDS             complement(1263..2078)
                     /locus_tag="VQ540_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000617844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HET2545566.1"
                     /translation="MIRFLVLAGYFELTIYLHLSGKLNQYINMHYSYLAYISMVLSFI
                     LAIVQLYIWMKQVKTHSHLNSRLAKMTSISLLAIPLVIGLTFPTVSLDSQTVSAKGYH
                     FPLSEGTDLAIQTSEGTTSQYLKPDTSSYFSKSAYEKEMRTAADKYLSQDSIQITNEN
                     YMEVMEAIYDYPDEFEGKTIQFTGFVYNDPSHANSQFLFRFGIIHCIADSGVYGLLTK
                     GNTRQYENNTWITAKGKLVNHYHKELKQNLPTLEIDSFTKVDKPENPYVYRAF"
     gene            complement(2075..2980)
                     /locus_tag="VQ540_001808"
     CDS             complement(2075..2980)
                     /locus_tag="VQ540_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HET2545567.1"
                     /translation="MTAFQQLPSSVLQTGAIFLSIIIEALPFVLIGSIVSGLIEVYIT
                     PDKVYHFLPRNRWGRIFFGTFVGMLFPSCECGIVPIINRFLEKKVPSYTAVPFLVTAP
                     VINPIVLFATYSAFGNSFHVALLRALGSILVAVILGIFLGFFWQEPIQKENRLACHEH
                     DFSYLSSAKKVFQVFVQAIDEFFDTGRYLVFGCLFASIIQVYVPTRILTSISATPLFA
                     ILLLMILAFLLSLCSEADAFIGASLLSSFGLAPVLAFLVIGPMLDIKNILMMKNYLKA
                     RFISHFITIVTLVVLVYSLLIGVIL"
     gene            complement(3251..3334)
                     /locus_tag="VQ540_001809"
                     /pseudo
     CDS             complement(3251..3334)
                     /locus_tag="VQ540_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            3378..5507
                     /locus_tag="VQ540_001810"
     CDS             3378..5507
                     /locus_tag="VQ540_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HET2545568.1"
                     /translation="MDKKYEKISQDLGVMLKQIDTVLSLTAEGATIPFIARYRKDMTG
                     SLDEVAIKAIIDLDKSLTNLNDRKEAVLAKIQEQGKLTKELEEAILVAEKLADVEELY
                     LPYKEKRRTKATIAREAGLFPLARLILQNIVDLEKEAEKFVCEGFATGKEALTGAVDI
                     LVEALSEDVTLRSMTYQEVLRHSKLTSQAKDESLDEKQVFQIYYDFSETVGTMQGYRT
                     LALNRGEKLGVLKIGFEHATDRILAFFATRFKVKNAYIDEVVQQSVKKKVLPAIERRI
                     RTELTEKAEEGAIQLFSDNLRNLLLVAPLKGRVVLGFDPAFRTGAKLAVVDATGKMLT
                     TQVIYPVKPASARQIEEAKKDLADLIGQYGVEIIAIGNGTASRESEAFVAEVLKDFPE
                     VSYVIVNESGASVYSASELARQEFPDLTVEKRSAISIARRLQDPLAELVKIDPKSIGV
                     GQYQHDVSQKKLSESLDFVVDTVVNQVGVNVNTASPALLSHVAGLNKTISENIVKYRE
                     EEGKITSRAQIKKVPRLGAKAFEQAAGFLRIPESSNILDNTGVHPENYTAVKELFKRL
                     DIKDLNEEAQSKLKSLSVKEMAQELDLGPETLKDIIADLLKPGRDFRDSFDAPVLRQD
                     VLDIKDLVVGQKLEGVVRNVVDFGAFVDIGIHEDGLIHISHMSRKFIKHPSQVVSVGD
                     LVTVWVKKIDTEREKVNLSLLAPNETD"
     gene            5494..5943
                     /locus_tag="VQ540_001811"
     CDS             5494..5943
                     /locus_tag="VQ540_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HET2545569.1"
                     /translation="MKLTDYVKQVSLEDFGRAFIHHVQWNRRLRSTGGRFFPKDGHLD
                     FNPKVYQKLGMEVFRKIVRHELCHYHLYFQGKGYQHKDRDFKELLKAVDGLRFVPSLP
                     NSNSKPLKLYRCQSCQQRYQRKRRIDTKRYRCGLCRGKLLLINQPED"
     gene            6002..6274
                     /locus_tag="VQ540_001812"
     CDS             6002..6274
                     /locus_tag="VQ540_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HET2545570.1"
                     /translation="MNSKFYKMRRNRMISGVLAGLSDKWNFDVTLVRFLFAIFTVANF
                     GLGVIIYIILASIMPTKEEIEAEMYGTGPRKRKEAQAIDDNEGWFW"
     gene            complement(6628..6819)
                     /locus_tag="VQ540_001813"
     CDS             complement(6628..6819)
                     /locus_tag="VQ540_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2545571.1"
                     /translation="MKHKEHILIGLLYLLSPFIGQLLVEHTHFIGTEFTGTAYVICWL
                     SVVISIHHFSKNVLSQQQK"
     gene            7247..8005
                     /locus_tag="VQ540_001814"
     CDS             7247..8005
                     /locus_tag="VQ540_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2545572.1"
                     /translation="MTLLDVKHVQKIYKTRFQGNQVEALKDIHFTVEKGDYVAIMGES
                     GSGKSTLLNILAMLDKPSRGQVYLNGTDTATIKNSQASSFRREKLGFVFQDFNLLDTL
                     SVKDNILLPLVLSRRPITEMMKKLVVTAENLGINQLQEKYPYEISGGQKQRVAVARAI
                     ITEPEILLADEPTGALDSKSSAALLDVFDEINERGQTILMVTHSTAAASRAKRVLFIK
                     DGILYNQIYRGEKTERQMFQEISDTLTVMASEVN"
     gene            8007..9995
                     /locus_tag="VQ540_001815"
     CDS             8007..9995
                     /locus_tag="VQ540_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2545573.1"
                     /translation="MFRLTNKLAVSNLIKNRKLYYPFALAVLLAVTVTYLFYSLTFNP
                     KIAEIRGGTTIQATLGFGMFVVTLASAIIVLYANSFVMKNRSKELGIYGMLGLEKRHL
                     ISMTFKELVVFGILTVGAGIGIGALFDKLIFAFLLKLMKLKVELVATFQTKVVITVLV
                     VFGLIFLGLMFLNALRIARMNALQLSREKASGEKKGRFLPLQTILGSISLGIGYYLAL
                     TVKDPLTALTTFFIAVLLVIFGTYLLFNAGITVFLQILKKNKKYYYQPNNLISVSNLI
                     FRMKKNAVGLATIAILSTMVLVTMSAATSIFNSSESFKKVLNPHDFGVSGQNVEKEDL
                     DKLLSQFASDKGYSVKEKEVLRYSNFGIANQEGTKLTIFEKGQNRVQPKTVFMVFDQK
                     DYENMTGQKLSLSGNEVGLFAKNEGVKEQKALTLNDHQFSVKEEFTKDFIVNHVPNQF
                     NILTADYNYLVVPDLQAFLDQFPDSAIYNQFYGGMNVNASEAEQLKVAEEYEKYLQKF
                     NAQLNTEGNYVYGSTLADASAQMSALFGGVFFIGIFLSIIFMVGTVLVIYYKQISEGY
                     EDRERFIILQKVGLDQKQIKQTINKQVLTVFFLPLLFAFLHLAFAYHMLSLILKVIGV
                     LDTTMMLIVTLSICAIFLIAYVLIFMITSRSYRKIVQM"
     gene            complement(10037..10681)
                     /locus_tag="VQ540_001816"
     CDS             complement(10037..10681)
                     /locus_tag="VQ540_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VIT family protein"
                     /protein_id="HET2545574.1"
                     /translation="MLRAGVLDANDGIISIAGVVIGVASATTNIWIIFLSGFAAILAG
                     AFSMAGGEYVSVSTPKDTEEAAVSREKLLLDQDRELAKKSLYAAYIQNEEFKTSAQLL
                     TNKIFLKNPLKALVEEKYGIEYEEFTNPWHAAISSFVAFFLRSLPPMLSVTIFPSDYR
                     IPATVLIVGVALLLTGYTSARLGKAPTKTAMIRNLAIGLLTMGVTFLLEQLFSI"
BASE COUNT         3330 a         2014 c         2250 g         3166 t
ORIGIN      
        1 tgctaaaatc ttatcagtga gaagatttct taaagtttat tctttgtagt ttcatctgta
       61 ttagtacata atttaactta gagaaaatag gaggactaat cgaatggaat taaaagattt
      121 tacagaaaaa gaacaggaaa tgattaagaa aaggcttaca atgtctaata ttagtgacaa
      181 agaaactact gagaagattc tggcgctagt cccacaagac ttgattaagc gaatcccgtt
      241 ttttgtcaga aaacatgcta caacacgtac gattaaacgt atttcaattg aataccctga
      301 actctacgct gtagctcaaa caagtggtga gattccagaa aaaaacgcga agaattgcgt
      361 cagattatca caactatctt tgaacaaaag atgaataagc atagtattaa gtagagaatg
      421 aaaaaatatt ttattggcgg tttgggaagc aatgcctatc atagcaagga ttttcttcaa
      481 gaactagatt cgcaggtcta ttttctaaat ccatatgaaa agcatcttcg agatgaaaca
      541 gaattgaaat catggtttaa aaatgagatt gtagaggaag aatctatctg tctgataggt
      601 cattctattg gaggcgattt agctcgttat ttcgcatcgg aatttgaaga agtaaagaaa
      661 ctgattcttt tggatggtgg ctatctagat ttagataaga ttttaccttt ggatacagag
      721 ttagaggaaa ctaaaaatta tatcaaatct caaattattt cggacttaga tgttcttact
      781 tctaaagaaa aatctgaagc aaagcattgg tcagaaaata tggagaaagc tgtaagacag
      841 tcctatcact ggaatgttga gtataataga tatgagttgg ctataaatta tgaaaatata
      901 gaagcgatac tccgcctacg gagaaaaata caagctttta agagagaagt gggagatacc
      961 ttgtttatta gtcctcgcta tcctaatgaa gctacatgga gagaggaagc cctaaaagaa
     1021 ttgccagact attttgatac tattttttta gaaaactttg gccatgagct ttatactcaa
     1081 gcacctaaag aaatcgctag tctaatgaat gagtggctcg cttattttct atgagctact
     1141 tgtattgctg gaaatggtat aagatgaaaa tctacaagtc actaattttc atataacaaa
     1201 aaacgaacag gctctttttc tgttattcag aagagaactt gttcgttttt atcttgattt
     1261 tcttaaaaag ctctatatac atagggattt tctggtttat cgactttggt aaagctgtcg
     1321 atttccaagg ttggaaggtt ttgtttgagt tctttatggt agtgattgac cagttttcct
     1381 ttggctgtta tccaagtgtt gttttcatac tgccgggtat tgcccttggt cagcaatcca
     1441 tagacaccag aatctgcgat acagtggata atgccgaatc ggaacagaaa ttgactattg
     1501 gcatgactgg ggtcgttata gacaaagcct gtaaactgga ttgtcttgcc ctcaaactca
     1561 tctggatagt cgtagatagc ctccatgact tccatatagt tttcattagt gatctgaata
     1621 ctatcttggg ataagtattt atccgccgcc gttcgcattt ccttttcata ggctgatttt
     1681 gaaaaataag aactggtatc tggtttcaaa tattggcttg tcgtcccttc gcttgtctga
     1741 atggctagat ctgttccttc cgataggggg aaatgataac ctttagcaga aacggtctga
     1801 gaatccaagc taacagttgg gaaagttaag ccgatgacaa gtggaatagc cagaagagaa
     1861 atactcgtca tcttggccaa tcggctgttc agatgactgt gggttttgac ttgcttcatc
     1921 cagatataca attgaacaat tgccaagata aaggaaagca ccatggagat ataggccaga
     1981 taggaatagt gcatgttgat gtactggttt agtttgcccg acagatggag gtaaatagtc
     2041 agttcaaaat agccagctaa aactaaaaat cgaatcatag gatgactcca atcaagagag
     2101 aatagactaa gacgacaaga gttacaatcg ttatgaagtg actgataaat cgtgctttca
     2161 agtaattttt catcatgaga atatttttga tatccagcat tggaccaatg acgagaaagg
     2221 ccagaactgg tgccaaaccg aaactcgaga gaagagaagc acctataaag gcatccgcct
     2281 cactacagag cgaaagaaga aaggccaaaa tcatcaagag caggatggca aaaagaggag
     2341 tcgcactgat agaggtcaga atccgagtcg gaacgtagac ctgtattata gaagcaaaga
     2401 ggcagccaaa taccaaataa cgccccgtat caaaaaattc atcaatggcc tgcacaaaga
     2461 cttgaaaaac tttttttgca gaactcaagt aagaaaaatc atgctcatga caagccagac
     2521 gattttcttt ctgaatcggt tcttgccaga aaaatcctag aaaaattcct agtattacag
     2581 ccacaagaat ggaacccaga gctcgtaata gggcgacatg gaaggagttg ccaaaggcag
     2641 aataggtcgc aaaaagaaca atgggattga taacaggtgc tgtcacaaga aaaggaacgg
     2701 ctgtgtaact gggaaccttt ttttccagaa aacgattgat gatggggacg attccacatt
     2761 cacaagaagg gaaaagcata ccgacaaagg tcccaaaaaa gattctcccc caacgatttc
     2821 gagggagaaa atgataaacc ttgtcaggtg tgatataaac ttcaatcagc cctgagacaa
     2881 tgcttcctat tagaacgaag ggaagggctt caatgataat ggagagaaaa atggctccag
     2941 tttgaagtac actagatggg agttgttgaa aagcagtcat ctagtttttc ttttctgctt
     3001 tggctttttt ctctttgtca tcagggaaag taacttgttt caaatcaggg agtttagcaa
     3061 actcttcaaa catcttgtcc aagtcgtctc gttttgtaaa ttttacagcc ataggtgtac
     3121 ctcgattcta aagtctacct ctattatact attattttgc ggaaaaggga gttttttaat
     3181 ttgttttcga tagttgatac acttcgaaaa tctcttcaaa ccacgtcagc ttcgccttac
     3241 cgtatatatg tgacttatcc acaacctcaa aacagtattt tgagcagcct gcggctagct
     3301 tcctagtttg ctttttgatt ttcattgagt atgaaaagga ttggagaaag ccttccagct
     3361 tgtggtataa tagatttatg gataaaaaat atgaaaaaat ctctcaggat ttgggagtga
     3421 tgttaaagca aattgatacc gttctaagtt tgacagctga aggggcgact attcccttta
     3481 tcgcgcgtta tcgcaaggac atgactggta gtctggatga ggtggcgatt aaggctatta
     3541 ttgatttgga taaaagtctg acaaatctca atgaccgtaa ggaagctgtc ttagctaaga
     3601 ttcaagaaca aggtaagttg accaaggaat tggaagaagc tatcttagtt gccgaaaaat
     3661 tagcagacgt tgaagaactc tatcttcctt ataaggaaaa gcgtcgtacc aaggcaacca
     3721 ttgcccgtga agctggactc tttcctcttg ctcgtttgat tttgcagaat atagttgact
     3781 tagagaaaga agctgaaaag ttcgtctgtg aaggatttgc gactggcaag gaagccttga
     3841 ccggtgcagt tgatattttg gtcgaagcct tatcggaaga tgtgaccttg cgttctatga
     3901 cttatcagga agtgctgaga cactctaaac ttacttctca agccaaggat gaaagtcttg
     3961 atgaaaagca ggtttttcag atttattatg atttttcaga gacagttgga actatgcaag
     4021 gctatcgtac cttggctctc aatcgtgggg agaaacttgg tgtcttgaag atcggttttg
     4081 aacatgcgac ggaccgtatt cttgccttct ttgctactcg tttcaaggtg aaaaatgctt
     4141 atattgatga agttgttcag caatccgtta agaaaaaggt cttgcctgct atcgagcgtc
     4201 gtattcggac agaattaact gagaaagctg aagaaggagc tatccaactt ttttctgaca
     4261 atctgcgcaa tctcctcttg gttgctccac tgaaagggcg cgtggttctt ggatttgacc
     4321 cagcctttcg tacaggtgcc aagttagctg tcgtggatgc aacaggaaaa atgctgacaa
     4381 ctcaggttat ttatcctgtt aaaccagcat cagctcgtca aatcgaagaa gccaagaaag
     4441 atttagcaga tttaattggt caatacggtg tagagattat tgccattgga aatggaacgg
     4501 ccagtcgtga aagtgaagct tttgtagcgg aagttctgaa agatttccct gaagtcagct
     4561 atgttatcgt taatgaaagt ggtgcttctg tctattctgc cagcgaactt gctcgtcagg
     4621 agtttccaga cttgaccgtt gaaaaacgct ctgccatttc tatcgcccgt cgtttgcaag
     4681 atcctcttgc ggaattggtc aaaatcgatc ctaagtcaat tggtgtcggt caataccaac
     4741 acgatgtcag tcagaagaaa ctatctgaga gtctggactt tgttgtcgat acagtggtta
     4801 accaagttgg tgtcaatgtc aatacagcta gcccagctct tctttcacac gtagctggac
     4861 tcaacaaaac tatctctgaa aatattgtca aataccgcga ggaagaagga aaaatcactt
     4921 cacgcgccca aatcaagaaa gttcctcgtc tgggagccaa ggcctttgag caggctgctg
     4981 gtttccttcg tatccctgaa agtagcaata tccttgataa tacaggagtt cacccagaga
     5041 attacactgc agttaaggaa ctcttcaaac gtttagatat taaagaccta aacgaagaag
     5101 cccaaagcaa actcaagtcc ctttcagtca aggaaatggc tcaagagcta gacctcggtc
     5161 cagaaaccct taaagatatc attgcagatc ttctcaaacc aggtcgagat ttccgtgatt
     5221 cctttgacgc acctgtgctt cgccaagatg tcctagatat caaagaccta gtggtaggtc
     5281 agaagctaga aggtgttgtg cgtaacgttg ttgacttcgg tgccttcgtt gatatcggga
     5341 ttcacgagga cggcttgatt catatttctc atatgagtcg caagtttatc aaacacccta
     5401 gtcaagtggt gtcagttgga gatttggtga ccgtttgggt caagaaaatt gatactgaac
     5461 gtgaaaaagt taatctgtcg ctcctcgctc caaatgaaac tgactgatta tgtcaagcag
     5521 gtttcactag aagacttcgg gagagctttt atccatcatg tccagtggaa taggcgtcta
     5581 cgttcgacag gtgggcgatt tttccccaaa gatgggcatc tggattttaa tcccaaggtt
     5641 tatcagaaac tgggtatgga ggtttttagg aaaattgtcc gacatgaact ctgtcattat
     5701 cacctttatt tccaagggaa gggctatcaa cacaaggatc gggattttaa ggaactgttg
     5761 aaagcagtgg atggattaag gtttgtacca tccttgccca atagtaactc taaaccactc
     5821 aagctttatc gttgtcaatc ctgccagcaa aggtatcagc gcaagcgtag gattgatacc
     5881 aaacgctatc gctgtggact ttgtcgaggt aaattgcttc tgataaatca gcctgaggac
     5941 tgatgaaagc cgagcctccc cgtgatatac tatgtctaac ctagcagaaa gaggaaatat
     6001 catgaacagt aaattttata aaatgagacg caatcgcatg atttcaggag ttctggcagg
     6061 tctgtcagac aagtggaatt ttgatgttac cctagttcgt ttcttgtttg ccatttttac
     6121 agttgcaaac tttggacttg gcgtgattat ctatatcatc ctagcttcta tcatgcctac
     6181 caaggaagaa atcgaagcag aaatgtacgg aacaggccca cgtaaacgca aagaagccca
     6241 agccattgac gacaatgaag gctggttttg gtgaggttct acagaagatt tggaataagc
     6301 aaaaagcttt aaatcaatag tctaaactgc ttgatttaaa gcttttttac ttttatactc
     6361 aataaaaatc aaagtgcaaa ctaggaagcc agccacaggc tgtaatttag tcggcaatgt
     6421 gaagttgaca tagtttgcac tttgattttt gaatagtatt aataatattt cgccagcttc
     6481 atccacaaac tatagtggat tggaactaga atagtacacc tctacttcta aaacattgtt
     6541 agaaatcgat ttgactatcc tgatcgattt gtcctgttct tatttcattt tattataaaa
     6601 gcagtaattt aaactcagtt ttttaatcta tttttgctgc tgagacaata catttttgga
     6661 aaaatggtgg atgctgataa caactgataa ccagcaaata acataagcag tgccggtaaa
     6721 ttctgtaccg ataaagtgtg tgtgttcaac taagagctga ccgatgaatg gagagagcag
     6781 atagagaagt ccgatgagta tatgttcttt gtgtttcatt aaagcgcacc ttctttcctt
     6841 ataggttgaa cgacttgcaa gtgttaaatt gaatggtatg ttatctaggt aagcttactc
     6901 aaatgatagt tcccgcttcc tcctttccaa agtaagcctt ttcatactta tattttacaa
     6961 ctttaaaaat aggaaatcaa atcattttct aagtaatttt gcttatattt cacccaatct
     7021 tacaaaaatg taagattaaa gtctcttttg taaggttagg ttatggcaag cggtcttttt
     7081 ttgatgtaaa ctagactcat aaagaacaaa ggagtaacat catgaaacaa atcttacata
     7141 agaaaactag aaaaccaagt cacaaagaaa ttgagcgcgt tcagctggga tgcactatga
     7201 tgcaagctac atttcatttg atgggatatt aagaaaggag attctcatga cacttttaga
     7261 tgtaaaacac gttcaaaaaa tttataaaac acgttttcag ggcaaccaag tagaagccct
     7321 caaggatatt cactttaccg tcgaaaaggg tgactacgtt gccatcatgg gtgagtctgg
     7381 ttctggtaaa tcaactcttc tcaatattct agctatgctg gataaaccaa gtcgtggtca
     7441 ggtttacttg aatggaactg acaccgcaac cattaaaaat tcacaggcct ctagcttccg
     7501 tcgtgaaaag ttgggctttg tcttccaaga ctttaacttg ctagatactc tatctgtaaa
     7561 ggacaatatc ttgcttccgc ttgtcttgtc aagaagacct attacagaga tgatgaagaa
     7621 attggtggtg acagctgaga atctgggaat aaaccaatta caagagaagt acccttacga
     7681 gatttctggt ggccagaaac agcgtgtagc agtagcacgc gccatcatca ctgaacctga
     7741 aattctcctt gcggacgaac cgacaggagc tcttgactcc aagtcatctg cagccttact
     7801 tgatgtcttt gatgaaatca atgagcgcgg ccaaaccatt ctcatggtaa cccactcaac
     7861 agcagcagct agcagagcta aacgtgtact ctttatcaaa gacggcattc tttacaatca
     7921 aatctaccgt ggagagaaga cagaacgtca gatgttccaa gaaatctctg ataccttgac
     7981 tgtcatggca agcgaggtga attagtatgt ttcgattaac caataagtta gcggtatcga
     8041 acttgattaa aaaccgcaaa ctctactatc cttttgcgct ggctgttctc ttggcagtca
     8101 ctgtcaccta tctcttttac tctctaacct tcaatcccaa gattgctgaa attcgtggag
     8161 gaacaaccat tcaggctaca cttggatttg gtatgtttgt cgtcaccctt gcgtcagcca
     8221 ttatcgttct ctatgccaat agttttgtca tgaagaaccg ttccaaggaa ctaggaattt
     8281 atggcatgtt gggcttggag aagcgtcatc ttatcagtat gacctttaag gagttagtgg
     8341 tatttgggat tctaactgtt ggagcgggta tcggtattgg agccttgttt gacaagttaa
     8401 ttttcgcttt cctgctcaaa ctaatgaaat tgaaggttga gctggttgct accttccaga
     8461 cgaaagttgt cattacagtg cttgttgtct tcggtttgat tttcctaggc ctcatgttcc
     8521 tgaatgccct tcgaatcgcc cgtatgaatg ccctccagct ctctcgtgag aaagctagtg
     8581 gagagaaaaa aggtcgcttc cttcctctcc aaaccattct tggttccata agtttaggaa
     8641 ttggctatta tcttgccctt acggtaaaag atcctcttac agccttaaca accttcttca
     8701 tagctgtttt actggttatc tttgggactt atctcttgtt taatgcaggg attaccgttt
     8761 tcctccaaat cttaaagaaa aataagaaat actattacca accaaataat ctcatatctg
     8821 tttctaactt gattttccgt atgaagaaaa atgcagttgg actagccacc atcgctatct
     8881 tgtcaacaat ggttttggta accatgtcag cagcgacaag cattttcaat tcctcagaaa
     8941 gctttaaaaa agttctaaat cctcatgatt ttggggtttc agggcaaaat gttgaaaaag
     9001 aagacttgga caaactcttg agccagtttg caagtgacaa aggttatagt gtcaaagaga
     9061 aagaagtact tcgttacagt aactttggta ttgcaaatca agaaggaact aagttaacta
     9121 tttttgaaaa aggacaaaac cgtgtccaac caaaaacagt tttcatggta tttgaccaaa
     9181 aagattatga aaatatgact ggtcaaaaac tgtctctatc aggaaatgag gtcggactct
     9241 ttgcaaagaa tgagggagtt aaagaacaga aagctctaac tctaaatgat catcaatttt
     9301 ctgtaaaaga agaatttact aaagatttta ttgtcaacca tgttccaaat cagtttaata
     9361 ttttgactgc tgattacaat taccttgttg tacctgattt acaagccttt ttggatcaat
     9421 tcccagattc ggctatctat aatcagtttt acggtggtat gaatgtaaat gccagtgaag
     9481 cagaacaact caaggtcgct gaggagtatg aaaaatactt acaaaagttt aatgctcaat
     9541 taaacactga aggtaactat gtgtatggta gcactctagc agatgctagt gctcagatga
     9601 gtgccctctt tggtggtgtc ttctttatcg gtattttctt atccattatc tttatggtcg
     9661 gaaccgttct ggtcatctac tacaaacaaa tttctgaagg atatgaagac cgtgagcgct
     9721 ttattatctt gcagaaagtc ggtttagatc aaaagcaaat caagcaaacc atcaacaaac
     9781 aggttttaac tgtattcttc cttcctttgc tctttgcctt cctacatcta gcctttgcct
     9841 accatatgct tagtctgatt ttaaaagtga ttggtgtact ggatacgact atgatgttga
     9901 ttgtgacctt gtctatctgc gctatcttcc tcatcgccta tgtgctgatt ttcatgatta
     9961 cttcaagaag ttatcgcaag attgtgcaaa tgtaaaaaag atacctcgac ttcaaaatcg
    10021 aggtatttct tgtattctaa atgctgaaaa gttgttcgag caggaaggta actcccatgg
    10081 tcaagagacc aatagcaagg ttccgaatca tagctgtttt ggttggggct tttccaagtc
    10141 tagcacttgt gtaaccagtg agaagaaggg ccacaccgac aataaggacg gtagcaggga
    10201 tgcggtaatc acttggaaaa atggtcactg acagcattgg aggcaaactt ctaaggaaaa
    10261 aggcaacgaa gctagaaatg gcagcgtgcc aaggattggt aaattcttca tactcaatcc
    10321 catatttttc ctctaccaga gccttgagtg gatttttaag aaagatctta ttagtcaaga
    10381 gttgggcaga agttttgaat tcttcatttt ggatataagc agcatagagg gattttttgg
    10441 ctagttccct atcttggtct agcaagagtt tttctcgcga aacggcagct tcctcggtat
    10501 cttttggagt tgaaacggat acatattctc caccagccat tgaaaaggca ccagctaaga
    10561 tagccgcaaa tcctgataaa aagataatcc agatattggt cgtggcactg gcaaccccga
    10621 taaccacacc agcaatggaa ataattccat cgttagcatc aagaacaccc gcacgcagga
    10681 tatttaaacg acctgcaaaa tttgaatcaa tttcgtgatt tgtttctgac gctaaatttc
    10741 aagttcaagt tagccatcca
//
LOCUS       DAVBDR010000065        10604 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.065, whole genome shotgun sequence.
ACCESSION   DAVBDR010000065 DAVBDR010000000
VERSION     DAVBDR010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10604)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10604)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10604
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.065"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            complement(7..1221)
                     /locus_tag="VQ540_001817"
     CDS             complement(7..1221)
                     /locus_tag="VQ540_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HET2545575.1"
                     /translation="MKEYNKSSKLEHVAYDIRGPVLEEAMRMRANGEKILRLNTGNPA
                     EFGFTAPDEVIHDLIMNARDSEGYSDSKGIFSARKAIMQYCQLKKFPNVDIDDIYLGN
                     GVSELIVMSMQGLLDNGDEVLVPMPDYPLWTAAVSLAGGNAVHYICDEAVEWYPDIDD
                     IKSKITSNTKAIVLINPNNPTGALYPKELLLEIIEIARQNDLIIFADEIYDRMVMDGH
                     VHTPVASLAPDVFCVSMNGLSKSHRIAGFRVGWMVLSGPKTHVKGYIEGLNMLSNMRL
                     CSNVLAQQVVQTSLGGHQSVDELLLPGGRIYEQRNFIYNAIQDIPGLSAVKPKAGLYI
                     FPKIDRNMYRIDDDEQFVLDFLKQEKVLLVHGRGFNWQEPDHFRIVYLPRVDELAQIQ
                     EKMTRFLKQYRR"
     gene            complement(1377..1670)
                     /locus_tag="VQ540_001818"
     CDS             complement(1377..1670)
                     /locus_tag="VQ540_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009014348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2545576.1"
                     /translation="MMKNSFQKSNFLYYGIILVSVLVKVIMICQLESLVPLLYPSFIG
                     FLVFHVLYHLILFLVAKRSGRWDYLMIWGLFLMFNLLYDSFLGLLFLGLSFGM"
     gene            1832..2284
                     /locus_tag="VQ540_001819"
     CDS             1832..2284
                     /locus_tag="VQ540_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HET2545577.1"
                     /translation="MAQRYQNIMVAIDGSKEADLAFVKGVHSALRNDAKLTIAHVIDT
                     RALQSVSTFDAEVYEELQVDAESLMKEYEKRAKDAGVADVHIVIEMGNPKTLLARTIP
                     DAEEVDLILVGATGLNAFERLLVGSSSEYILRHAKVDLLVVREQEKTL"
     gene            complement(2319..3707)
                     /locus_tag="VQ540_001820"
     CDS             complement(2319..3707)
                     /locus_tag="VQ540_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000453140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HET2545578.1"
                     /translation="MEVKAVFFDIDGTLVNNRKSVLKSTKDAIKIVKEQGVLVGVATG
                     RGPFFVKELMDDLDLDFAVTYNGQYIFSKDRVLFTSPISKLHLRHLISYAKKEGTEIA
                     LGTKDAMLGSKIMSFGLGSFSQRISRFVPSVLTRTVSQSFNRMVSKVVPQKEEDLLHL
                     MNQPIYQVLMLMTPEESEKAAADFEDLKLTRSNPFASDVINQGNSKLEGIRRVGKEYG
                     FDLNQVMAFGDSDNDLEMLAGVGMSVAMGNGSSSVKEAAKHITTSNQQDGIHKALEHF
                     GVLSSEKVFVSRDYHFNKVKTFHHMMDERTQEEPRAWDLEGATHRAGFKIEELVEFVR
                     AASPSEEDFGQAVSQLHQALDKAAGKVAKKTPAQQDLIGQVDALIDTLYFTYGSFVLM
                     GVDPERIFDIVHQANMGKIFPDGKAHFDPVTHKILKPDNWEEKYAPEPAIKKELQRQL
                     KAYERHKERNKS"
     gene            3773..4735
                     /locus_tag="VQ540_001821"
     CDS             3773..4735
                     /locus_tag="VQ540_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HET2545579.1"
                     /translation="MPKKILVLHTGGTISMQADASGAVVTSSDNPMNHVSNPLEGIQV
                     HALDFFNLPSPHIKPKHMLVLYQKIKEEADNYDGVVITHGTDTLEETAYFLDTMEVPH
                     MPIVLTGAMRSSNELGSDGVYNYLSALRVASDDRAADKGVLVVMNDEIHAAKYVTKTH
                     TTNVSTFQTPTHGPLGLIMKQEILYFKTAEPRVRFDLDHIQGLVPIISAYAGMTDELI
                     DMLDLEHLDGLIIQAFGAGNIPKETAQKLESLLQKGIPVALVSRCFNGIAEPVYAYQG
                     GGVQLQKAGVFFVKELNAQKARLKLLIALNAGLTGQALKDYMEG"
     gene            complement(4732..4923)
                     /locus_tag="VQ540_001822"
     CDS             complement(4732..4923)
                     /locus_tag="VQ540_001822"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2545580.1"
                     /translation="MNTIERTRRLVKGCATHCFEVVDETDEVSSKHVFEVVDRTDEVS
                     NHTYGRATLTWFAEIFEEY"
     gene            complement(4987..5997)
                     /gene="ccpA"
                     /locus_tag="VQ540_001823"
     CDS             complement(4987..5997)
                     /gene="ccpA"
                     /locus_tag="VQ540_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000990602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HET2545581.1"
                     /translation="MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEV
                     IDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFSSLAKGIDDIAEMYKYNIVLANS
                     DEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
                     VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKVGITYSEGL
                     VFESKYSYDDGYALAERLISSNATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSD
                     DSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREVLLPHGLTERSSTRK
                     RK"
     gene            complement(6422..7021)
                     /locus_tag="VQ540_001824"
     CDS             complement(6422..7021)
                     /locus_tag="VQ540_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET2545582.1"
                     /translation="MKVLVAEDQSMLRDAMCQLLTLQPDVESVLQAKNGQEAIQLLEK
                     ESVDIAILDVEMPVKTGLEVLEWIRSERLETKVVVVTTFKRAGYFERAVKAGVDAYVL
                     KERSIADLMQTLHTVLEGRKEYSPELMEVVMTRPNPLTEQEIAVLKGIARGLSNQEIA
                     DQLYLSNGTIRNYVTNILSKLDAGNRTEAANIAKESGWL"
     gene            complement(7022..8119)
                     /locus_tag="VQ540_001825"
     CDS             complement(7022..8119)
                     /locus_tag="VQ540_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001848091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET2545583.1"
                     /translation="MLERLKSIHYMFWASLIFMIFPILPVVTGWLSAWHLLIDILFVV
                     AYLGVLTTKSQRLSWLFWGIMLIYVAGNTAFVAVNYIWFFFFLSNLLSYHFSVRSLKS
                     LHVWTFLLAQVLVVGRLLIFQRIEVEFLVYLLGILTFVDLMTLGSVRIRLVEDLKEAQ
                     TKQNTQINLLLAENERNRIGQDLHDSLGHTFAMLSVKTDLALQLFQIQAYPQVEKELR
                     EIQQISKESMREVRTIVENLKSRTLTSELETVKKMLEIAGIEVEIANQLDTASLTQEL
                     ESTASMILLELVTNIIKHAKASKAYLKLERTDQELLLMVRDDGKGFETVTENELHTVR
                     ERVLPFSGEVSVISQKHPTEVQVRLPYKERK"
     gene            complement(8119..8856)
                     /locus_tag="VQ540_001826"
     CDS             complement(8119..8856)
                     /locus_tag="VQ540_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2545584.1"
                     /translation="MKRWIALNKIEFLLTKRQSVYYLLSVGMPTAFYLFFSGMYQDTP
                     GGPANFMRDYLISMTAFSMMSTAIFSFPAVLHTDKMNNWQKTLRHSPVNMVEYYLSKI
                     TSMMVDYLVSILVVFSVGHLVRGVDMSLGSWIGAAFLLIVGSIAFVALGLTLTLLPSS
                     QLMSVVGNLLYLGLAVLGGLWMPISLFPDWMQAIGKCLPTYQLMELLKTFLNEGSINL
                     SATVYLLVFSAVLFGLTIYLQGHKENA"
     gene            complement(8858..9742)
                     /locus_tag="VQ540_001827"
     CDS             complement(8858..9742)
                     /locus_tag="VQ540_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2545585.1"
                     /translation="MNMIKVQGLHKNIKSKAILKDISFEVAEGECVALIGPNGAGKTT
                     LLDCLLGDKLVTSGQVYIQDLPVTSSKLDYTRSYLPQENVIVQKLKVKELIAFFQRIY
                     PNPLNNQEIDQLLQFDQQQKEQFAEKLSGGQKRLLSFILTLIGRPKLVFLDEPTAAMD
                     TSTRQRFWEIVRDLKAQGVTILYSSHYIEEVEHTADRILVLNKGELIRDTTPLAMRSE
                     EIEKHFILPLAYKEVVEKSVLVENWVQKQDALQVVTCEADAFWELLVQAGCRIQEIEV
                     NNRSLLDTIFEETQKGDD"
     gene            complement(9729..9923)
                     /locus_tag="VQ540_001828"
     CDS             complement(9729..9923)
                     /locus_tag="VQ540_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2545586.1"
                     /translation="MKKAILFLFIGLSLVVWLVEMFTGWFDQSFLHQVIRGAWGLGFM
                     ISVVFPMGMEWLKGEYYEHD"
     gene            complement(9920..10126)
                     /locus_tag="VQ540_001829"
     CDS             complement(9920..10126)
                     /locus_tag="VQ540_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000503440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2545587.1"
                     /translation="MEEEEMRNKMIIAVSLVVAGVMTYLMFSGLDEGFYHFPWELFAS
                     FGIMSWLIREGLKLVRDVKKELEK"
BASE COUNT         3213 a         2412 c         1931 g         3048 t
ORIGIN      
        1 caagccctat ctacgatact gtttcaagaa acgagtcatc ttttcttgga tttgggctaa
       61 ctcatcaaca cgaggaaggt aaacgatacg gaagtggtct ggttcctgcc agttaaagcc
      121 tcgaccatga accaagagaa ccttttcctg cttcaagaaa tcaaggacaa actgctcatc
      181 atcatcgata cggtacatat tgcggtcgat ttttgggaag atatagagcc ccgccttggg
      241 tttaacggca gacaaacctg gaatatcttg aatggcatta tagatgaaat ttctttgctc
      301 gtagattcgt ccaccaggaa gaagcaattc atcgactgat tggtgacccc ccaaggaagt
      361 ttgtacgact tgttgggcca aaacgttaga gcaaaggcgc atattggaca gcatattgag
      421 cccttcgata tagcccttaa catgagtctt agggccagac aagaccatcc aacccacacg
      481 gaaacctgct atgcggtggg attttgacag accattcatg ctgacacaga agacatctgg
      541 tgccaagctc gccacaggcg tatgcacatg tccgtccatt accatgcggt catagatttc
      601 atccgcaaag ataatcaaat cgttttgacg ggcaatctca ataatctcca gcaagagttc
      661 cttaggataa agggctccag ttgggttatt tggattgata aggacaattg ccttggtatt
      721 ggaagtgatt tttgacttga tatcgtcaat atctgggtac cattccacag cttcatcaca
      781 gatatagtga acggcatttc ctccagctag gctgacagcc gccgtccata gaggatagtc
      841 tggcattggc actaagacct catccccatt gtccaaaagc ccctgcatgg acatgacaat
      901 caactcactg acaccatttc caaggtaaat atcatcaata tctacgtttg ggaatttctt
      961 cagctggcaa tactgcatga tggccttacg ggctgagaaa atccctttgg agtcagaata
     1021 gccttcacta tcacgcgcat tcataatcaa gtcatgaatg acctcgtctg gcgctgtaaa
     1081 gccaaattct gctggatttc ctgtattcag acgtaaaatc ttttctccat tcgctcgcat
     1141 ccgcatggct tcttccaata caggaccacg gatatcataa gcaacatgct ctaacttact
     1201 agacttgtta tattctttca tcttgtttcc tcaattcatc aggatagtaa cattatacca
     1261 ctagaaagag aatgcgacaa gtttactgaa atgtgttact agtttcgtat agaagaaaaa
     1321 ccttgctaaa ggcgaggtta agaacgtaga gatagcaggc attttgcaaa gacacatcac
     1381 ataccaaaag ataaacctag aaaaagcaag cctagaaagg agtcataaag aagattaaac
     1441 atgaggaaaa gcccccatat catcaagtaa tcccaacgcc cacttcgttt tgcaactaga
     1501 aataagatta gatggtagag tacatgaaag actaaaaatc caataaaact tggataaaga
     1561 agcggtacca gactctctaa ttgacagatc atgatcactt ttaccaagac tgaaactagg
     1621 ataattccat aatacaggaa atttgatttt tgaaaagagt ttttcatcat tctcccttcc
     1681 ttcacttctt tccttctatc ctttctttta ttttatcata tatttatata gattttaagc
     1741 cctaatattc ttttgaaaaa tacttttttt gctttacttc tatagtgaaa aggtttacaa
     1801 ttatagtaag aaaatttcag gaggtttcat tatggcacaa cgttaccaaa atatcatggt
     1861 cgcaatcgat ggttctaagg aagcggactt ggcttttgtc aagggagttc attctgctct
     1921 acgaaacgac gctaaactca ccatcgcaca tgtcattgac acacgcgctc tccaaagcgt
     1981 atccaccttt gatgctgaag tttacgaaga actccaagtc gacgctgaaa gtctgatgaa
     2041 agagtacgaa aaacgtgcta aagatgctgg ggtagcagat gttcatatcg tcattgaaat
     2101 gggaaatcca aagaccctgc tagcacgtac tattccagat gccgaggaag tggacctcat
     2161 cctcgttggc gcaactggtc tcaacgcctt tgaacgcctc ttggtcggct cttcatctga
     2221 atacatactc cgccatgcta aggtcgattt gctggttgtg agagaacaag aaaaaacctt
     2281 ataatcacaa agaaaaggag cccctagctc ctttttgttt acgatttatt tctctcttta
     2341 tggcgttcgt aagccttgag ctggcgctgc agttcctttt taatagcagg ttctggagca
     2401 tatttttctt cccaattatc tggttttaag attttatggg tcactggatc aaaatgagcc
     2461 ttgccatctg gaaaaatttt ccccatattg gcctgatgga caatatcaaa aatacgttct
     2521 gggtccaccc ccatcaagac aaaactgccg taggtgaagt aaagcgtgtc aatcaaggca
     2581 tccacttgcc ctatcaaatc ttgctgagca ggtgtcttct tggctacttt acctgctgcc
     2641 ttatcaaggg cctgatgaag ttgcgataca gcttgaccaa aatcttcttc agaaggactg
     2701 gctgctcgaa caaactccac caattcttct attttaaaac cagccctatg ggttgcaccc
     2761 tctaaatccc aagctcgagg ttcttcttgg gttcgttcat ccatcatgtg gtggaaggtc
     2821 ttgaccttat tgaaatgata gtcacggctg acaaagactt tttctgaaga caaaacacca
     2881 aaatgttcca aggccttgtg gatcccatct tgttgattgc tagtggtaat gtgcttggca
     2941 gcttccttga cactgctact accatttccc atagcgaccg acataccgac gccagccagc
     3001 atttcaaggt cattatctga gtcaccaaaa gccatgactt ggttgaggtc aaagccatat
     3061 tctttcccaa ctcggcgaat gccttctaat ttagaatttc cctgattgat gacatccgat
     3121 gcaaaaggat tgctacgtgt caatttcaag tcttcaaaat cagctgccgc cttctcagat
     3181 tcttctggtg tcatcagcat caaaacttgg tagataggct gattcatcag gtgaagcagg
     3241 tcctcttcct tttggggaac aaccttgctg accatgcgat taaaagactg actcaccgtc
     3301 cgagttaaaa cagagggaac gaagcgacta attcgttggg aaaaagaacc cagaccaaag
     3361 gacatgattt tagaacccaa catggcatcc ttggtcccta gggcaatctc cgtgccctct
     3421 tttttagcat agctaattag atggcgcaaa tgtaacttgg aaatagggct cgtgaacaag
     3481 actctgtctt tactaaagat atactggcca ttataggtta ccgcaaaatc cagatccaaa
     3541 tcgtccatca attccttaac aaaaaaaggt cctcgccctg tcgctacgcc aactagtacc
     3601 ccttgttctt tgacaatctt aatcgcgtcc ttagtggatt tcaaaacact cttgcgattg
     3661 ttgaccaagg ttccatcgat atcaaaaaaa acagctttga cttccatcct attccaatct
     3721 ccccttttgt gatacaatga ttataccaca tttcagaaag agtgagtaaa tcatgcctaa
     3781 gaaaatcctt gttttacata cgggtggaac tatttccatg caggccgatg cttctggcgc
     3841 tgttgtgacg agttcagata atcccatgaa ccatgtgtcc aacccacttg aaggaatcca
     3901 agtccacgcc ttggactttt ttaaccttcc aagtccccat atcaaaccca aacatatgct
     3961 ggtcctctac cagaaaatta aagaggaagc agataactac gatggagtgg taatcacaca
     4021 cggaaccgat actttagagg aaacagccta tttccttgat accatggaag ttccccatat
     4081 gcctatcgtt ctaacaggag ccatgcgtag ctccaatgag ctcggtagtg atggtgttta
     4141 taattaccta agtgctttac gagtggccag cgatgacagg gctgctgaca aaggagtttt
     4201 ggtcgttatg aacgatgaaa tccacgctgc caagtatgtc accaaaacac atacgactaa
     4261 tgtcagcacc ttccagactc caacacatgg ccccctcggt ctcatcatga aacaggaaat
     4321 cctctacttc aaaacagctg aacctcgtgt tcgctttgac cttgatcaca tacaaggttt
     4381 agtccctatc atctcggctt atgctggtat gacagatgag ctgattgata tgctggattt
     4441 agaacacttg gacggtttga ttatccaagc cttcggagct ggtaatattc ccaaagaaac
     4501 ggctcaaaaa ttagaaagcc ttctgcaaaa aggaatccca gtcgctctgg tatcacgatg
     4561 ctttaacggt attgccgagc ctgtttatgc ctaccagggt gggggcgtac agttgcaaaa
     4621 agcaggcgtt ttctttgtta aagaactcaa cgcccaaaaa gctcgcttga aactcctcat
     4681 cgccctcaat gccggactaa caggacaggc tttgaaagac tatatggaag gctaatactc
     4741 ttcgaaaatc tctgcaaacc acgtcagagt cgccctaccg tatgtatggt tactgacttc
     4801 gtcagttcta tctacaacct caaaaacatg ttttgagctg acttcgtcag tttcatctac
     4861 aacctcaaaa cagtgtgttg cgcagccttt aaccagccgc ctagtccgct ctatggtatt
     4921 cattaagtca acatctcttg tttaagagca caaaatcagg aaatcttctc gattccctga
     4981 ttttttctat ttacgttttc gtgttgagct acgttctgtc aaaccatgag gtaagagaac
     5041 ttcacgttct tccaactctt ccttatgcat aatcttggtc aacatacgca tactaatggc
     5101 accaaggtca taaagaggtt gggcaatcgt tgtcaagttt ggacgggtaa agcgtgagat
     5161 ttgtgaatca tcactagtaa taatttcaaa atcttctggc acagaaacac ccttatcagc
     5221 caaaccgttc aagactcctg ctgccaactc atcacctgtc acaactgctg cagttgcatt
     5281 tgatgaaatc aaacgctctg ctaaggcgta accatcatca tagctatatt tagattcaaa
     5341 taccaaaccc tcactataag tgattcctac ttttttcaag gtttccttgt agccaactaa
     5401 acgaacctta ccattgatgt catccactag cggaccgcta acgaaagcaa tacgctcatt
     5461 ttctttagca aggtagctca ctgcatcaat tgttgcttgc ttatagtcaa tattgacact
     5521 tggcaactgg tgctcaacat cgacagttcc tgcgagaaca atcggagtac gtgaacgcga
     5581 aaattctgag cgaattttat ctgtcaagtg ataacccata tagataatgc catctacctg
     5641 ctttgaaaag agggtattga caacagaaac ttctttctcg ttatcttcat cgctattagc
     5701 taggacaata ttgtacttgt acatttctgc aatatcatca atccccttag ccaaactcga
     5761 aaaataacca ttggtaatat ttggaatcac gacaccgaca gtggttgtct ttttacttgc
     5821 aagaccacgc gcaactgcat ttggacgata atccaaacga tcaattacct ctagcacttt
     5881 tttacgggta ttctctttta catttttatt gccattgacc acacggctga ccgtcgccat
     5941 ggaaacacct gcttcacgag cgacatcata aatggttact gtatcatctg cattcattcc
     6001 ttttcctgtc ctttctatct cacacattct tttacaagta gaggtactga ttgaagctct
     6061 atatctactt acaaaagtga agatgtgaaa atttcgtttt catatttcta cttattccat
     6121 tctatcacta attgtaaaca ctttcaagtg ttttttgaag attgattgaa aaaatttcat
     6181 agaaaaccta ggtttagctc cttgctacca ccttagacta aataaaaagg aggaaactaa
     6241 gcccttctaa agttatagta aaatgaaata agaacaggat aaatcgatca ggacagtcaa
     6301 atcgatttct aacaatgttt tagaagtaga ggtgtactat tctagtttca atctactata
     6361 ggtattgttc cattcactac cgtcaatttt agcacatagt cttcatgaaa atattatatc
     6421 atcataacca accagattct tttgcgatat tagctgcctc tgttcgatta ccagcatcca
     6481 gttttgaaag aatattggtg acatagtttc gaatagttcc gtttgagagg taaagctgat
     6541 ctgcgatttc ttggttggat aagccccggg cgattccctt taagacagca atctcttgtt
     6601 ctgtcaacgg attgggacgg gtcatcacca cttccatcaa ttcaggcgaa tactccttgc
     6661 gtccttcgag gacggtgtgc aaggtttgca tgaggtctgc aatgcttcgt tcctttaata
     6721 cataagcatc cactccagcc ttgaccgcac gttcaaaata cccagcacgc ttgaaggtcg
     6781 tcaccacaac cacctttgtt tcaagccttt ctgatcgtat ccactccaag acttcaagac
     6841 ctgtcttaac aggcatttct acgtcaagga tggcgatatc tacagactcc ttttctaata
     6901 gttggattgc ttcttgccca ttcttggctt gaaggacaga ctccacatct ggttgaagcg
     6961 tgagcaattg acacatagca tctcgcaaca tactttgatc ttctgcgact aatactttca
     7021 tctactttct ctccttataa ggtagtcgaa cttgcacttc cgttggatgt ttctgactga
     7081 ttacacttac ttctcctgaa aatggaagga cacgttctcg aactgtatgg agctcatttt
     7141 ctgttacagt ttcaaaacct ttcccgtcat ctctgaccat caggagcaat tcctgatctg
     7201 tgcgttctaa ttttaagtag gctttagacg ctttagcatg tttgatgatg ttggtcacta
     7261 attcaagcaa aatcatggaa gccgttgact ctaattcctg agttaagcta gctgtatcta
     7321 gttgattagc tatttccacc tcaattccag caatttctaa catctttttc acagtctcta
     7381 gttcggatgt caaagttcta gacttaagat tttccacaat ggttcgcact tcacgcattg
     7441 attctttgct aatctgctgt atttctctta attccttttc cacttgtgga taagcctgta
     7501 tttgaaataa ctgcaaggct agatcagttt taacactaag catagcaaag gtatgcccca
     7561 gactatcatg caaatcttga ccgatacgat tgcgctcatt ttctgctagc aatagattta
     7621 tctgggtatt ttgcttagtc tgagcttctt tcaaatcctc gacaaggcga attcgaaccg
     7681 agcccaaagt catcaaatca acaaaagtaa gaattccaag cagatagact agaaactcaa
     7741 cttcgattct ctgaaaaatc aaaagtcgcc ccacaacaag gacttgagca agaagaaaag
     7801 tccagacatg taaagacttt aaactacgta cgctgaaatg ataacttaag agattggaaa
     7861 ggaaaaagaa aaaccagata taattcacag caacaaaggc ggtattccca gctacataga
     7921 tcagcatgat cccccagaaa agccaagata ggcgctggct cttagttgtt aaaacaccca
     7981 aatatgccac tacaaataga atatcaatca ataaatgcca ggcagaaagc cacccagtca
     8041 ctacaggtag gatggggaaa atcataaaaa ttaaactggc ccaaaacata tagtgtatgc
     8101 ttttcagtct ttcaagcatt aagcattctc cttatgacct tgaaggtaaa tggtcaaacc
     8161 aaacaaaact gctgaaaaaa caagtagata aactgtggct gatagattga tgctaccctc
     8221 gtttaagaag gtcttgagca actccatcaa ctgataagtt ggtaggcact tcccgattgc
     8281 ttgcatccag tctggaaata aagagatggg catccagagt ccacctaaaa cagccaagcc
     8341 tagatagaga agattgccca cgacagacat cagctgacta gaaggcaaga gtgtcaaggt
     8401 caagccaagc gctacaaaag ctatacttcc tactatcagc aagaacgcag ccccaatcca
     8461 gcttcctaaa gacatatcca cacctctgac caagtgccca actgagaaaa caaccaggat
     8521 tgagaccaaa taatcaacca tcatacttgt tatctttgat agataatatt ctaccatatt
     8581 tacagggcta tgacgcaatg ttttctgcca gttgttcatc ttatcggtat gtaagacagc
     8641 tgggaatgaa aagatagcgg tcgacatcat ggaaaaggca gtcatggaga tgaggtagtc
     8701 gcgcataaaa ttagccggtc cacctggtgt gtcctggtac atgcctgaaa agaatagata
     8761 gaaggctgtc ggcatcccta cagataataa ataatagact gattgccgtt tggtcaatag
     8821 aaattctatc ttgtttagtg caatccatcg tttcatctta gtcatctccc ttctgtgttt
     8881 cttcaaagat tgtatccaac aaactacgat tattgacttc gatttcttgt atcctacatc
     8941 ctgcttgaac taacagttcc cagaaagcat ccgcttcgca tgtgactact tgtaaggcat
     9001 cttgtttttg tacccagttt tcaaccaaga ctgacttctc aacgacttcc ttgtaagcta
     9061 gcggaaggat aaaatgcttt tcaatctcct cactacgcat agctagaggc gtcgtgtcac
     9121 gaatcaactc tcccttattt aaaaccaaaa tccggtcagc tgtatgctct acctcttcaa
     9181 tataatgaga cgaatagaga atggtgactc cttgcgcttt taggtcccga acaatttccc
     9241 aaaaacgttg acgagttgaa gtatccatgg cagcagttgg ctcatctaaa aagacaagct
     9301 ttggtcgccc aattaaggtc aagataaaag ataaaagacg cttttgccca cctgacaatt
     9361 tttctgcgaa ttgctctttc tgttgctggt caaactgtaa tagttgatcg atttcctggt
     9421 tgttcaaggg atttggatag atacgttgaa agaaagcaat caactcttta acctttagtt
     9481 tttgaacaat tacattttct tgagggagat aggatctcgt atagtctaac ttagagctcg
     9541 ttaccggcaa atcttggata tatacttgcc cactggtgac caatttatct ccaagcaaac
     9601 agtccaagag tgtcgtctta ccagctccat ttggcccaat caaggcgacg cattcacctt
     9661 cagctacctc aaaggaaata tccttcaaaa tagccttact tttgatgttt ttatgtaagc
     9721 cttgtacctt aatcatgttc ataatattct cctttcaacc actccattcc catagggaaa
     9781 acgacggaaa tcataaatcc taatccccag gcgccgcgaa taacttggtg aagaaaggat
     9841 tgatcaaacc aacctgtaaa catttctacc aaccatacca ctagtgatag tccaataaaa
     9901 agaaagagaa tcgctttttt catttttcaa gctccttttt cacatctctt actaatttca
     9961 agccttctcg tatcaaccaa gacatgattc caaagcttgc aaacaactcc caaggaaaat
    10021 gatagaatcc ttcgtccaat cctgagaaca tgagataagt catgactcct gctactacta
    10081 aactcactgc gataatcatt ttatttctca tctcttcttc ctccatttca tactacaatt
    10141 atagtctttt gaaatcagag gagatagaag cttctgtcac taaaaaatat gacaaatgtc
    10201 ataaaaaatt ctgttcaaaa caagcaagat acactataca ataaaacaca attagataaa
    10261 tctaaggcaa cttcctcaaa agagatatca aaccccattc acactataat gtaaactaat
    10321 acttatttaa agtcaaaaga gcggaaattt ttatcgtaca aacatatata ttataggtaa
    10381 gacaaaaaac tcttcaatta ctttcttaaa aatttatagg agttataaaa tctattaaat
    10441 ttcaatgtgg atacctaaac tacagtattt attgaaaaga ctggagacaa aaagtatacg
    10501 ctgccaaaat gaattgctga aaatcaaaaa agagagaagc aaactgattc tctcttaatg
    10561 tatataatat ctagttataa aaatacacac tcacatatct ctgt
//
LOCUS       DAVBDR010000066        10362 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.066, whole genome shotgun sequence.
ACCESSION   DAVBDR010000066 DAVBDR010000000
VERSION     DAVBDR010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10362)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10362)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10362
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.066"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            <1..169
                     /locus_tag="VQ540_001830"
     CDS             <1..169
                     /locus_tag="VQ540_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="choline-binding protein"
                     /protein_id="HET2545588.1"
                     /translation="KDGDTWYYLEASGAMKASQWFKVSDKWYYVNGSGALAVNTTVDS
                     YRVNANGEWVN"
     gene            complement(399..1379)
                     /gene="dusB"
                     /locus_tag="VQ540_001831"
     CDS             complement(399..1379)
                     /gene="dusB"
                     /locus_tag="VQ540_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HET2545589.1"
                     /translation="MTNLNTPFMIGNIEIPNRTVLAPMAGVTNSAFRTIAKELGAGLV
                     VMEMVSDKGIQYNNEKTLHMLHIDEGENPVSIQLFGSDEDSLARAAEFIQENTKTDIV
                     DINMGCPVNKIVKNEAGAMWLKDPDKIYSIINKVQSVLDIPLTVKMRTGWADPSLAVE
                     NALAAEAAGVSALAMHGRTREQMYTGHADLETLYKVAQALTKIPFIANGDIRTVQEAK
                     QRIEEVGADAVMIGRAAMGNPYLFNQINHYFETGEILPDLTFEDKMKIAYEHLKRLIN
                     LKGENVAVREFRGLAPHYLRGTSGAAKLRGAISQASTLAEIEALLQLEKA"
     gene            complement(1366..2238)
                     /gene="hslO"
                     /locus_tag="VQ540_001832"
     CDS             complement(1366..2238)
                     /gene="hslO"
                     /locus_tag="VQ540_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000357853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HET2545590.1"
                     /translation="MDKIIKTISESGAFRAFVLDSTETVRTAQERHQTQASSTVALGR
                     TLIASQILAANEKGNTKLTVKVLGSSSLGAIITVADTKGNVKGYVQNPGVDIKKTATG
                     EVLVGPFVGNGQFLVITDYGAGNPYNSITPLISGEIGEDLAFYLTESQQTPSAVGLNV
                     LLDEEDKVKVAGGFLVQVLPGAKKEEIARFEKRIQEMPAISTLLESDDHIEALLKAIY
                     GDEAYKRLSEEEIRFQCDCSHERFMNALASLPSSDLQEMKEEDHGAEITCQFCQTTYN
                     FDEKDLEELIRDKS"
     gene            2403..3830
                     /locus_tag="VQ540_001833"
     CDS             2403..3830
                     /locus_tag="VQ540_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET2545591.1"
                     /translation="MYLGDLMEKAECGQFSILSFLLQESQTTVKAVMEETGFSKATLT
                     KYVTLLNDKALDSGLELTIHSEDENLRLSIGAATKGRDIRSLFLDSAVKYQILVYLLY
                     HQQFLAHQLAQELVISEATLGRHLAGLNQILSEFDLSIQNGRWRGPEHQIRYFYFCLF
                     RKVWSSQEWEGHMQKPERKQEIANLEEICGASLSAGQKLDLVLWAHISQQRLRVNACQ
                     FQVIEEKMRGYFDNIFYLRLLRKVPSFFAGQHIPLGVEDGEMMIFFSFLLSHRILPLH
                     TMEYILGFGGQLADLLTQLIQEMKKEELLGDYTEDHVTYELSQLCAQVYLYKGYILQD
                     RYKYQLENRHPYLLMEHDFKETAEEIFHALPAFQQGTDLDKKILWEWLQLIEYMAENG
                     GQHMRIGLDLTSGFLVFSRMAAILKRYLEYNRFITIEAYDPSRHYDLLVTNNPIHKKE
                     QTPVYYLKNDLDMEDLAGIRQLLFT"
     gene            3989..5497
                     /gene="glpK"
                     /locus_tag="VQ540_001834"
     CDS             3989..5497
                     /gene="glpK"
                     /locus_tag="VQ540_001834"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HET2545592.1"
                     /translation="MSQEKYIMAIDQGTTSSRAIIFNKKGEKVSSSQKEFTQIFPQAG
                     WVEHNANEIWNSVQSVIAGAFIESGVKPNQIEAIGITNQRETTVVWDKKTGLPIYNAI
                     VWQSRQTAPLAEQLKSQGYVEKFHEKTGLIIDAYFSATKVRWILDHVEGAQERAEKGE
                     LLFGTIDTWLVWKLTDGAAHVTDYSNAARTMLYNIKELKWDDEILEILNIPKAILPEV
                     RSNSEIYGKTAPFHFYGGEVPISGMAGDQQAALFGQLAFEPGMVKNTYGTGSFIIMNT
                     GEEMQLSENNLLTTIGYGINGKVYYALEGSIFIAGSAIQWLRDGLRMVENSPESEKYA
                     RDSHNNDEVYVVPAFTGLGAPYWNQNARGSVFGLTRGTSKEDFIKATLQSIAYQVRDI
                     IDTMQVDTQTAIQVLKVDGGAAMNNFLMQFQADILGIDIARAKNLETTALGAAFLAGL
                     SVGYWKDLDELKLLNETGELFEPSMNESRKEQLYKGWKKAVKATQVFAEVDD"
     gene            5539..7365
                     /gene="glpO"
                     /locus_tag="VQ540_001835"
     CDS             5539..7365
                     /gene="glpO"
                     /locus_tag="VQ540_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HET2545593.1"
                     /translation="MEFSKKTRELSIKKMQERTLDLLIIGGGITGAGVALQAAASGLE
                     TGLIEMQDFAEGTSSRSTKLVHGGLRYLKQFDVEVVSDTVSERAVVQQIAPHIPKPDP
                     MLLPVYDEDGATFSLFRLKVAMDLYDLLAGVSNTPTANKVLSKDQVLERQPNLKKEGL
                     VGGGVYLDFRNNDARLVIENIKRANQDGALIANHVKAEGFLFDESGKITGVVARDLLT
                     DQVFEIKARLVINTTGPWSDKVRNLSNKGTQFSQMRPTKGVHLVVDSSKIKVSQPVYF
                     DTGLGDGRMVFVLPRENKTYFGTTDTDYTGDLEHPKVTQEDVDYLLGIVNNRFPESNI
                     TIDDIESSWAGLRPLIAGNSASDYNGGNNGTISDESFDNLIATVESYLSKEKTREDVE
                     SAVSKLESSTSEKHLDPSAVSRGSSLDRDDNGLLTLAGGKITDYRKMAEGAMERVVDI
                     LKAEFDRSFKLINSKTYPVSGGELNPANVDSEIEAFAQLGVSRGLDSKEAHYLANLYG
                     SNAPKVFALAHSLEQAPGLSLADTLSLHYAMRNELALSPVDFLLRRTNHMLFMRDSLD
                     SIVEPILDEMGRFYDWTEEEKATYRADVEAALANNDLAELKN"
     gene            7435..8139
                     /locus_tag="VQ540_001836"
     CDS             7435..8139
                     /locus_tag="VQ540_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HET2545594.1"
                     /translation="MMNELFGEFLGTLILILLGNGVVAGVVLPKTKSNSSGWIVITMG
                     WGIAVAVAVFVSGKLSPAHLNPAVTIGVALKGGLPWASVLPYILAQFAGAMLGQILVW
                     LQFKPHYEAEENAGNILATFSTGPAIKDTVSNLISEILGTFVLVLTIFALGLYDFQAG
                     IGTFAVGTLIVGIGLSLGGTTGYALNPARDLGPRIMHSILPIPNKGDGDWSYAWIPVV
                     GPVIGAALAVLVFSLF"
     gene            8436..8639
                     /locus_tag="VQ540_001837"
     CDS             8436..8639
                     /locus_tag="VQ540_001837"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2545595.1"
                     /translation="MPKWSNPDYVNELDPKIVDMLVEFHKSQGTLETPEAQAEIAQKR
                     EEIEQRRAELEDKKQELLNRLNK"
     gene            complement(8726..9313)
                     /locus_tag="VQ540_001838"
     CDS             complement(8726..9313)
                     /locus_tag="VQ540_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2545596.1"
                     /translation="MFVFADDSLSANSKVVSGEAQFENGSSVRFGDTQVNILSDEVLE
                     VVNPDGSVDTIERRADGVYINGAFYMAYQKNEIDLNISFRSYDPNVWNYVNTIHGNKQ
                     ANTFANFMTGAGISYMIGRIGTLLGGPWGAIIGGAYFGIQAYQSYLDSQSPYPYYITS
                     TYIHVAQKKWKFITEYYRNSNYTGYVKTVTTYVNF"
BASE COUNT         3017 a         2048 c         2368 g         2929 t
ORIGIN      
        1 gaaagatgga gatacctggt actatcttga agcatcaggt gctatgaaag caagccaatg
       61 gttcaaagta tcagataaat ggtactatgt caatggctca ggtgcccttg cagtcaacac
      121 aactgtagat agctatagag tcaatgccaa tggtgaatgg gtaaactaaa cctaatataa
      181 ctagttaata ctgacttcct gtaagaactc tttaaagtat tccctacaaa taccatatcc
      241 tttcagtaga taatataccc ttgtaggaag tttagataaa aaaataactc tgtaatctct
      301 agccggattt atagcgctag agactacgga gtttttttga tgaggaaaga atggcggcat
      361 tcaagaggct ctttaagaga gttacgggtt ttaaactatt aagccttctc caattgcaag
      421 agggcttcaa tctctgccag ggtgctagct tgcgaaatgg ctccacggag tttggcagcg
      481 ccagatgttc cacggagata gtgaggagcg aggccgcgga attcacgaac tgcgacgttt
      541 tctcctttga ggttaatcaa tcgtttcaag tgttcgtagg cgatcttcat cttgtcttca
      601 aaggtcaaat caggtaggat ttctcctgtt tcaaagtaat ggttgatttg gttgaagagg
      661 taaggatttc ccatggcagc tcggccaatc atgactgcgt cagcaccaac ttcttcgatg
      721 cgttgcttgg cttcttggac agtacggata tcaccgttgg cgatgaatgg aatcttggtt
      781 agagcttggg caaccttgta aagggtctca aggtctgcgt ggccagtata catttgttca
      841 cgggtacggc catgcatggc gagggcagaa acacctgcag cctcagcagc gagggcattt
      901 tctactgcaa gagatgggtc cgcccatccg gtacgcattt tgacagtaag tgggatatca
      961 aggacagact ggaccttgtt gatgatagag tagatcttgt caggatcctt gagccacata
     1021 gctccagctt cgttcttcac gattttgttg acagggcagc ccatgttgat atcgacgata
     1081 tcggtcttgg tgttttcttg gatgaattct gctgcgcgtg ctaggctgtc ttcatcgcta
     1141 ccaaaaagtt ggatagagac agggttttcg ccctcatcga tatgaagcat gtgcagggtt
     1201 ttttcgttgt tgtattggat tcccttgtca gagaccattt ccattacaac gagtccagct
     1261 ccgagctctt ttgcgatggt acgaaaggct gagttggtca cgccagccat aggcgctaaa
     1321 acggtacgat tgggaatctc aatattgcca atcataaaag gtgtattaag atttgtcacg
     1381 aatgagttcc tccaggtcct tttcatcaaa gttgtaagta gtttggcaga attgacaagt
     1441 gatttctgcc ccgtggtctt cctctttcat ttcctgtaag tctgagcttg gaaggctggc
     1501 aagagcgttc ataaagcgtt catggctaca gtcacattgg aaacggattt cttcttcaga
     1561 aagacgcttg taggcttcgt ccccgtagat agccttgagg agggcttcga tatggtcgtc
     1621 gctttcgaga agagtagaga tagctggcat ttcttggatg cgtttttcaa agcgagcaat
     1681 ctcttctttc ttggctcctg gcaagacttg aactaggaaa ccacctgcaa ccttgacctt
     1741 gtcttcctcg tccaaaagga cattgaggcc gaccgctgaa ggcgtttgtt ggctttcagt
     1801 aaggtaaaag gcaaggtctt caccgatttc tccagagatg aggggagtta tagagttgta
     1861 aggatttcca gcaccgtagt ctgtgataac gaggaattga ccatttccaa caaaaggtcc
     1921 gactaggact tcaccagtcg cagtcttttt gatgtcaaca ccaggatttt gaacatagcc
     1981 tttgacgttc cccttggtat cagcgacggt gataatagca cctagagagc tagagcccaa
     2041 caccttaact gtaagtttgg tatttccttt ttcattggct gcgagaatct ggctagcgat
     2101 aagagttcga ccaagcgcta cagttgagct agcttgggtt tgatgtcttt cttgagcagt
     2161 gcggacggtt tccgtgctat caaggacaaa agcacgaaag gctccgcttt ctgatatagt
     2221 tttaataatt ttatccatag ctactatttt agcataaaaa tgcccaaagg gggagccgtg
     2281 tgtttactga ttttcaggat aatggaccag gaaatcagca tgaaaataaa aagagaaaca
     2341 gattatttca gcatttgtaa gatttatgct atgcttaagg tagaaaatga aaggggtaac
     2401 aaatgtattt aggagatttg atggagaaag ccgagtgtgg tcaattttca atcctttcct
     2461 ttctattaca agagtctcag acgaccgtca aggctgtaat ggaagaaaca ggattttcaa
     2521 aagcaaccct aaccaaatat gtcaccctgc tcaatgacaa ggctttggat agtggcttag
     2581 aactgactat tcactcagaa gatgaaaatc tgcgtctgtc tatcggtgca gctaccaagg
     2641 ggagagatat tcggagcttg tttttggata gtgctgttaa ataccagatt ttggtttatc
     2701 ttctctacca ccaacagttt ttagcccatc agctggctca agaattggtg attagcgagg
     2761 ctacgcttgg tcgtcacttg gctggtttaa atcagatttt gtcagaattt gatttatcca
     2821 tccaaaatgg acgctggaga ggtccagagc atcagattcg ctatttctat ttctgtcttt
     2881 tccgaaaggt ctggtcgagt caggaatggg aaggtcacat gcagaaacca gagagaaaac
     2941 aggagattgc caatttagag gaaatctgcg gtgcaagttt gtctgcgggg cagaaattgg
     3001 acttggttct ctgggctcac atcagtcaac aacgtcttcg ggtcaatgct tgtcagtttc
     3061 aagtcataga agagaaaatg cgagggtatt ttgacaatat cttttatctt cgtttgctga
     3121 gaaaggttcc gtcctttttt gctgggcaac atattccact aggagttgag gatggtgaga
     3181 tgatgatatt cttctctttt ctcctatctc atcgcattct tcctcttcat actatggagt
     3241 atattcttgg ttttggaggg cagttggcag atttactgac gcaattgatt caagaaatga
     3301 agaaggagga actattgggg gattatacag aggaccatgt cacctatgaa ctcagtcagc
     3361 tttgtgctca agtctatctc tataagggct atattttaca ggatcgctac aagtaccagt
     3421 tagagaatcg tcatccatat ttactgatgg aacatgattt taaagagaca gcagaggaga
     3481 tttttcatgc tctacctgct tttcaacagg ggacagattt agataagaag attctctggg
     3541 aatggctcca gttaatcgaa tatatggctg aaaacggtgg ccagcatatg cggattggtc
     3601 tggatttgac atctggtttt cttgtctttt caaggatggc agccattttg aaacggtatt
     3661 tggaatacaa tcgttttatt accattgaag cttatgaccc tagtcggcat tatgatttgc
     3721 tggttaccaa taacccgatt cataagaagg aacagacacc agtctattat ttaaaaaacg
     3781 acttggatat ggaagatttg gcagggattc gtcagttatt attcacttaa aaggcttggt
     3841 taatctaggt cttttttgtg aaattcacac aatctcctca cattttttta aaaattaaaa
     3901 aaagttgata aacaagaaag cgctttattt tgtatactag taagtgtaaa gaggaaacac
     3961 ctcaagatct ttatcaggag gacagtacat gtcacaagaa aaatacatca tggccattga
     4021 ccagggaact acaagttctc gtgccatcat tttcaacaaa aaaggggaaa aggttagctc
     4081 gagtcaaaaa gagtttaccc agattttccc tcaggcaggt tgggttgagc acaatgccaa
     4141 tgaaatttgg aactctgttc agtcagttat tgcgggtgct ttcatcgaaa gtggtgtcaa
     4201 gccaaatcaa atcgaggcaa tcgggattac caaccaacgt gaaacaacgg ttgtctggga
     4261 taagaaaaca ggacttccta tctacaatgc tatcgtttgg cagtcacgcc agacagcacc
     4321 tttggctgag caactaaaaa gccaaggtta tgtggaaaaa ttccatgaaa agactggttt
     4381 gattattgat gcttacttct ctgctaccaa ggttcgttgg attttggatc atgtagaagg
     4441 tgctcaagag cgagcagaaa aaggggaatt gctctttggt actatcgata cttggttggt
     4501 ttggaaattg actgacggtg cggctcacgt gactgactac tcaaatgcag ctcgtaccat
     4561 gctttataac attaaagaac tcaaatggga tgatgagatt ttggaaatcc ttaacattcc
     4621 gaaggctata cttccagaag ttcgttctaa ctccgaaatc tacggcaaga cagctccatt
     4681 ccatttctac ggtggagagg tgccaatctc aggtatggct ggggaccaac aagcagccct
     4741 ctttggacag ttggcttttg agccaggtat ggttaagaat acttatggaa caggctcttt
     4801 catcatcatg aatactgggg aagagatgca gttgtctgaa aacaacctct tgacaaccat
     4861 tggttacgga atcaacggta aggtttatta tgccttggaa ggttctatct tcatcgcagg
     4921 aagtgctatt cagtggcttc gtgacggtct tcgcatggtt gaaaattcac cagaatctga
     4981 aaaatacgct cgtgattctc acaacaacga tgaagtttat gtcgttccag cctttacagg
     5041 tctaggcgct ccatactgga accaaaatgc tcgtggttcc gtctttggtt tgactcgtgg
     5101 aacaagcaaa gaagacttta tcaaggcgac tttgcaatct attgcttatc aagtgcgtga
     5161 tatcatcgac accatgcaag tggatactca gaccgccatt caagtactga aggtggatgg
     5221 tggtgcagcc atgaacaact tcctcatgca gttccaggcg gatattttag gcattgacat
     5281 tgcacgtgct aaaaacctgg aaacaacagc tctaggagcg gccttcctag caggtttgtc
     5341 agtagggtac tggaaagact tggacgagtt gaaactcttg aacgagacag gagaactctt
     5401 tgagccatct atgaacgaat ctcgcaagga acaactctac aagggctgga agaaggctgt
     5461 gaaagcaact caagtctttg cggaagtaga cgactaatac tggcagaata aagcgattta
     5521 tttagaaagt gtgtaaatat ggaattttca aagaaaacac gtgaattgtc aattaaaaaa
     5581 atgcaggaac gcaccctgga cctcttgatt atcggtggag gaatcacagg agctggtgta
     5641 gccttgcagg cggcagctag cggtcttgag actggtttga ttgaaatgca agactttgca
     5701 gaaggaacat ctagtcgttc aacaaaattg gttcacggag gacttcgtta ccttaaacaa
     5761 ttcgacgtag aagtggtctc agatacggtt tctgaacgtg cagtggttca acaaatcgct
     5821 ccacacattc caaaaccaga cccaatgctc ttaccagttt acgatgaaga tggagcaacc
     5881 tttagcctct tccgtcttaa agtagccatg gacttgtacg acctcttggc aggtgttagc
     5941 aacacaccaa ctgcgaacaa ggttttgagc aaggatcaag tcttggaacg ccagccaaac
     6001 ttgaagaagg aaggcttggt aggaggtgga gtgtatcttg acttccgtaa caacgatgcg
     6061 cgtctcgtga ttgaaaacat caaacgtgcc aaccaagacg gtgccctcat tgccaaccac
     6121 gtgaaggcag aaggcttcct ctttgacgaa agtggcaaga ttacaggtgt tgtagctcgt
     6181 gatctcttga cagaccaagt atttgaaatc aaggcccgtc tggttattaa tacaacaggt
     6241 ccttggagtg ataaagtacg taatttgtct aataagggaa cgcaattctc acaaatgcgc
     6301 ccaactaagg gagttcactt ggtagtggat tcaagcaaaa tcaaggtttc acagccagtt
     6361 tactttgaca caggtttggg tgacggtcgt atggtctttg ttctcccacg tgaaaacaag
     6421 acttactttg gtacaactga tacagactac acaggtgatt tggagcatcc aaaagtaact
     6481 caagaagatg tagattatct acttggcatt gtcaacaacc gctttccaga atccaacatc
     6541 accattgatg atatcgaaag cagctgggca ggtcttcgtc cattgattgc agggaacagt
     6601 gcctctgact ataatggtgg aaataacggt accatcagtg atgaaagctt tgacaacttg
     6661 attgcgactg ttgaatctta tctctccaaa gaaaaaacac gtgaagatgt tgagtctgct
     6721 gtcagcaagc ttgaaagtag cacatctgag aaacatttgg atccatctgc agtttctcgt
     6781 gggtctagct tggaccgtga tgacaatggt cttttgactc ttgctggcgg taaaatcaca
     6841 gactaccgta agatggctga aggagctatg gagcgcgtgg ttgacatcct caaagcagaa
     6901 tttgaccgta gctttaaatt gatcaattct aaaacttacc ctgtttcagg tggagaattg
     6961 aacccagcaa atgtggattc agaaatcgaa gcctttgcgc aacttggagt atcacgtggt
     7021 ttggatagca aggaagctca ctatctggca aatctttacg gttcaaatgc accgaaagtc
     7081 tttgcacttg ctcacagctt ggaacaagcg ccaggactca gcttggcaga tactttgtcc
     7141 cttcactatg caatgcgcaa cgagttggct cttagcccag ttgacttcct tcttcgtcgt
     7201 accaaccata tgctctttat gcgtgatagc ttggatagca tcgttgagcc aattttggat
     7261 gaaatgggac gattctatga ctggacagaa gaagaaaaag caacttaccg tgctgatgtc
     7321 gaagcagctc tcgctaacaa cgatttagca gaattaaaaa attaagaaaa aataaaagag
     7381 gtggagggca gcattccttg tcgcccgtcc cttcttttta atggagacag aaagatgatg
     7441 aatgaattat ttggagaatt tctagggact ttaatcctga ttcttctagg aaatggtgtt
     7501 gttgcaggtg tggttcttcc taaaaccaag agcaatagct caggttggat tgtgattact
     7561 atgggttggg ggattgcagt tgcggttgca gtctttgtat ctggcaagct cagtccagct
     7621 catttaaacc cagctgtgac catcggtgtg gccttaaaag gtggtttgcc ttgggcttcc
     7681 gttttgcctt atatcttagc ccagttcgca ggggccatgc tgggtcagat tttggtttgg
     7741 ttgcaattca aacctcacta tgaggcagaa gaaaatgcag gcaatatcct ggcaaccttc
     7801 agtactggac cagccatcaa ggatactgta tcaaacttga ttagcgaaat ccttggaacc
     7861 tttgttttgg tgttgacaat ctttgctttg ggtctttacg attttcaggc aggtatcgga
     7921 acctttgcag tgggaacttt gattgtcggt atcggtctat cactaggtgg gacaacaggt
     7981 tatgccttga acccagctcg tgaccttgga cctcgtatca tgcacagcat cttgccaatt
     8041 ccaaacaagg gagacggaga ctggtcttac gcttggattc ctgttgtagg ccctgttatc
     8101 ggagcagcct tggcagtgct tgtattctca cttttctagt ttatactctt cgaaaatcaa
     8161 attcaaacca cgtcagcgtc gccttaccgt actcaagtac agcttacggc tagcttccta
     8221 gtttgctctt tgattttcat tgagtattag aaaacaatta tgttgataga gcttgggcaa
     8281 gagcccaatt tcagcaaaaa atgaagtaaa tcttctcata ataaaacgca tcatatcaag
     8341 cacgaaaatt ccacgaggtc aactacagtc agaaagctga acaacaagcc aaaacgccca
     8401 aaaaaggcgg caaaaagcaa gcacctgcaa gcaacgtgcc gaaatggtca aatcctgatt
     8461 atgtcaacga attagaccca aaaatcgttg atatgctagt agaatttcac aagtcacaag
     8521 gcactttgga aactcccgag gcgcaagcag aaatcgccca aaaacgtgaa gaaatcgagc
     8581 aaaggagagc tgagcttgag gataaaaaac aagagctttt gaaccgcttg aacaaataga
     8641 gtttcgcaag tattatgctt acaaattact tgagcaatta actaaaatat aaaccctgcc
     8701 tttatatcta ggcagggttt atattttaga aattcacgta ggttgttacg gtttttacat
     8761 acccagtata gtttgagttt ctatagtatt cagtgataaa cttccatttt ttttgagcaa
     8821 catggatata agtacttgtt atgtagtatg gatatgggct ttgtgaatcc aagtaagact
     8881 gataagcttg tataccaaaa tatgctccac caattattgc accccatgga ccccccaata
     8941 aagtacctat cctaccaatc atataactga ttccagcacc agtcatgaag ttagcgaatg
     9001 tgttagcttg tttattccca tgtattgtgt tgacgtaatt ccaaacatta ggatcgtatg
     9061 atctaaaaga tatatttagg tcgatttcat tcttttgata agccatataa aatgccccat
     9121 tgatatagac gccgtcagca cgtcgttcaa tagtgtctac acttccatct ggattgacaa
     9181 cctcaagaac ttcatcgctt aaaatattta cttgcgtatc tccgaaccgc actgatgagc
     9241 cattctcaaa ctgagcctca ccagatacaa ctttagagtt tgccgataag ctatcatcag
     9301 caaaaacaaa caagcgacgg ggaaatgcta gacatacaga aaacagacat aactagcaaa
     9361 cacatgcatt taaacatctt agacataacg gaaactcctt tgtatttttg atttttttca
     9421 acttttatta tacaataaaa ccaaataaaa agaaagcggt aacaatatgc ttaatgcgaa
     9481 aattttttat atatttttat gtttgatcgt tatcgaaact acaggcttgt tgttgttgaa
     9541 aagaggtctc gaaatgggtt atttagacac agaagctatt atcctcgcag ttttttcatt
     9601 tgctttttac aacctatgtt cattcgcttg ggtctgctct acaataaaaa acaataaaaa
     9661 ataaatagac gtattttcaa aaaaaaaaaa aaaaaaatgc atatttatct tagcaaaacg
     9721 acaatttaaa tcgtcgtttt tttgtagtac gacgggcatg tcgtatatct gaggtgtaag
     9781 tcctcggtgg gcacctgcta ccggtgaacc caatagcgat tcccaagcct gactatcgtg
     9841 aggtagcagg gagaggaagg gatagcgaaa tcgtggctct acgaacagga acgtgatagt
     9901 aaggcgtata tagcggataa ggaggcttca aactctaaag tccaaaaagg tagtcgtaac
     9961 ctatatgtgt aaatcacgag agtaattgaa ttcggactaa ggtttgtgtg aaaaagataa
    10021 atctttctag agtctaaaga ctctgcgtca gatttcctat tttcactgta accttttaac
    10081 gtcctcatat cttgtataaa cgaggaaaga tgtacgactt atcccgtgag gtttcatgag
    10141 cgctgaaagc gtagtaacaa cgaatcatga gaagtcagcc gagcccatag tagtgaggaa
    10201 acttccgtaa tggaagtgga gcgaaggggt gaatactcaa acagtctggg gagagactgt
    10261 ttgaggtctg tcgctagaaa gagaaaacga cagatcgaag taatcctact tcacttgtgt
    10321 ctgtaaaatg agtggtctga tagaactgga ctttgacacg ta
//
LOCUS       DAVBDR010000067        10116 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.067, whole genome shotgun sequence.
ACCESSION   DAVBDR010000067 DAVBDR010000000
VERSION     DAVBDR010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10116)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10116)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10116
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.067"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            588..986
                     /locus_tag="VQ540_001839"
     CDS             588..986
                     /locus_tag="VQ540_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000877383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein"
                     /protein_id="HET2545597.1"
                     /translation="MKYRLFFVIFLSSVLDILLGTFLQISIVSIGWLVLYSGLFEVGV
                     FLLANKGVAVKIKEVDIRNRFKFIFGKTLWFQILLLIFLIIKLYLGLDARLILFYGHI
                     FIVFNALMYLLSSSQVSLKKKQTVFLILQQ"
     gene            1024..1713
                     /locus_tag="VQ540_001840"
     CDS             1024..1713
                     /locus_tag="VQ540_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000760553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET2545598.1"
                     /translation="MKKYQLLFKISAVFSYLFFVFGLSQLTLIVQNYWQFSSQIGNFV
                     WIQNILSLLFIGVMIVVLVKTGHGYLFRIPRKKWLWYSILTVLVVVFQISFNVQTAKH
                     VQSTAEGWAVLIGYSGTNFAELGIYIALFFLVPLMEELIYRGLLQHAFFKHSRFGLDL
                     LLPSILFALPHFSSLPSLLDIFVFATVGIIFAGLTRYTKSIYPSYAVHVINNIVATFP
                     FLLTFLHRVLG"
     gene            1755..2003
                     /locus_tag="VQ540_001841"
     CDS             1755..2003
                     /locus_tag="VQ540_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2545599.1"
                     /translation="MYKHLFFLDSKTLDRLTPYILVLASDTIAFNVFVLTFVSAVVFN
                     FLNSMLALMAIFIGAGYVVGFWLLKWFVLERLELKDDA"
     gene            2033..2644
                     /locus_tag="VQ540_001842"
     CDS             2033..2644
                     /locus_tag="VQ540_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET2545600.1"
                     /translation="MEFFDKFHALCFGFLVLIIVITVPYTINHGGFFQNESALILVSL
                     LVTSLSVAYARKFEMISFGMLSKKQLLLFIAIFLLSVLETLVYIHFFAVSSGSGVQHL
                     AEVSRGISLSLILTTSVFGPIQEELIFRGLLQGAVFDNSWLGLVLTSSLFSFMHGPSN
                     VPSFIFYLLGGLLLGFAYKKSQNLWVSTLVHMFYNSWPLLYYL"
     gene            2805..3599
                     /locus_tag="VQ540_001843"
     CDS             2805..3599
                     /locus_tag="VQ540_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000363010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HET2545601.1"
                     /translation="MDLGDNELTLTPIPGKSGKAYMGSYPDGKRIFVKMNTSPILPGL
                     AREQIAPQLLWSRRLADGRDMCAQEWLTGKILTPYDMNRKQIVNILTRLHRSRPLMTQ
                     LSRLGYAMETPVDLLQSWQETAPDALRKNHFISEVMADLRQTIPGFREDHATIVHGDV
                     RHSNWIETDSGLIYLVDWDSVRLTDRMFDVAHMLCHYISEHQWKEWLTYYGYKYNQTV
                     LSKLYWYGQLSYLSQISKYYMNQDLENVNREIHGLRHFRDKYGKRR"
     gene            3596..4231
                     /gene="trmB"
                     /locus_tag="VQ540_001844"
     CDS             3596..4231
                     /gene="trmB"
                     /locus_tag="VQ540_001844"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001266107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HET2545602.1"
                     /translation="MRVRNRKGATELLEANPQYVVLNPLEAKAKWRDLFGNDNPIHVE
                     VGSGKGAFVSGMAKQNPDINYIGIDIQKSVLSYALDKVLEVGVPNIKLLWVDGSDLTD
                     YFEDGEIDRLYLNFSDPWPKKRHEKRRLTYKTFLDTFKRILPENGEIHFKTDNRGLFE
                     YSLVSFSQYGMKLNGVWLDLHASDFEGNVMTEYEQKFSNKGQVIYRVEAEF"
     gene            4357..4836
                     /gene="rimP"
                     /locus_tag="VQ540_001845"
     CDS             4357..4836
                     /gene="rimP"
                     /locus_tag="VQ540_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HET2545603.1"
                     /translation="MDAIATIVELVREVVEPVIEAPFELVDIEYGKIGSDMILSIFVD
                     KPEGITLNDTADLTEIISPVLDTIKPDPFPEQYFLEITSPGLERPLKTKDAVAGAVGK
                     YIHVGLYQAIDKQKVFEGTLLAFEEDELTMEYMDKTRKKTVQIPYSLVSKARLAVKL"
     gene            4880..6016
                     /gene="nusA"
                     /locus_tag="VQ540_001846"
     CDS             4880..6016
                     /gene="nusA"
                     /locus_tag="VQ540_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HET2545604.1"
                     /translation="MSKEMLEAFRILEEDKGIKKEDIIDAVVESLRSAYRRRYGQSDS
                     VAIDFNEKTGDFTVYTVREVVDEVFDSRLEISLKDALAINSAYELGDKIKFEEAPAEF
                     GRVAAQSAKQTIMEKMRKQTRAITYNTYKEHEQEIMSGTVERFDNRFIYVNLGSIEAQ
                     LSKQDQIPGEVFASHDRIEVYVYKVEDNPRGVNVFVSRSHPEMIKRLMEQEIPEVYDG
                     TVEIMSVAREAGDRTKVAVRSHNPNVDAIGTIVGRGGANIKKITSKFHPARYDAKNDR
                     MVPIEENIDVIEWVADPAEFIYNAIAPAEVDQVIFDENDSKRALVVVPDNKLSLAIGR
                     RGQNVRLAAHLTGYRIDIKSASEFEAMEDAASVELEVENDTVEE"
     gene            6038..6331
                     /locus_tag="VQ540_001847"
     CDS             6038..6331
                     /locus_tag="VQ540_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000857559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HET2545605.1"
                     /translation="MKTRKIPLRKSVVSNEVIDKRDLLRIVKNKEGQVFIDPTGKANG
                     RGAYIKLDNAEALEAKKKKVFNRSFSMEVEESFYDELIAYVDHKVKRRELGLE"
     gene            6324..6623
                     /locus_tag="VQ540_001848"
     CDS             6324..6623
                     /locus_tag="VQ540_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HET2545606.1"
                     /translation="MNKQKISNLLGLAQRAGRIISGEELVVKAIQDGKAKLVFLAHDA
                     GPNLTKKIQDKSHYYQVEIVTVFSTLELSIAVGKSRKVLAVTDAGFTKKMRSLME"
     gene            6640..9432
                     /gene="infB"
                     /locus_tag="VQ540_001849"
     CDS             6640..9432
                     /gene="infB"
                     /locus_tag="VQ540_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HET2545607.1"
                     /translation="MSKKRLYEIAKELGKESKEVVARAKELGLDVKSHSSSVEEAVAA
                     KIAASFKPAAAPKVEAKPAAPKVSAEKKAEKSEPAKPAVAKEEAKPAEPVAPKTEKVA
                     VKPQSRNFKAEREARAKEQAERRKQNKGNNRDQQQNGNRQKNDGRNGGKQGQSNRDNR
                     RFNDQAKKQQGQQKRRNERRQQEDKRSNQAAPRIDFKARAAALKAEQNAEYARSSEER
                     FKQYQAAKEALAQANKRKEPEEIFEEAAKLAEQAQQVQAVVEVVPEKKEPAVDTRRKK
                     QARPDKNRDDYDHEEDGPRKQQKNRSSQNQVRNQKNSNWNNNKKNKKGNNKNNRNQTP
                     KPVTERKFHELPTEFEYTDGMTVAEIAKRIKREPAEIVKKLFMMGVMATQNQSLDGET
                     IELLMVDYGIEAKQKVEVDNADIERFFVEDGYLNEDELVERPPVVTIMGHVDHGKTTL
                     LDTLRNSRVATGEAGGITQHIGAYQIVENGKKITFLDTPGHAAFTSMRARGASVTDIT
                     ILVVAADDGVMPQTIEAINHSKAANVPIIVAINKIDKPGANPERVIGELAEHGVMSTA
                     WGGDSEFVEISAKFNQNIEELLETVLLVAEIQELKADPTVRAIGTVIEARLDKGKGAV
                     ATLLVQQGTLNVQDPIVVGNTFGRVRAMTNDLGRRVKVAGPSTPVSITGLNEAPMAGD
                     HFAVYEDEKSARAAGEERAKRALMKQRQATQRVSLENLFDTLKAGELKSVNVIIKADV
                     QGSVEALSASLQKIDVEGVKVTIVHSAVGAINESDVTLAEASNAFIVGFNVRPTPQAR
                     QQAEADDVEIRLHSIIYKVIEEMEEAMKGMLDPEFEEKVIGEAVIRETFKVSKVGTIG
                     GFMVINGKVARDSKVRVIRDGVVIYDGELASLKHYKDDVKEVTNGREGGLMIDGYNDI
                     KMDDVIEAYVMEEIKR"
     gene            9683..10033
                     /gene="rbfA"
                     /locus_tag="VQ540_001850"
     CDS             9683..10033
                     /gene="rbfA"
                     /locus_tag="VQ540_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HET2545608.1"
                     /translation="MANHFRTDRVGMEIKREVNEILQKKVRDPRVQGVTITDVQMLGD
                     LSVAKVYYTILSNLASDNQKAQIGLEKATGTIKRELGRNLKLYKIPDLTFVKDESIEY
                     GNKIDEMLRNLDKN"
BASE COUNT         3074 a         1851 c         2308 g         2883 t
ORIGIN      
        1 attcaagatt tggatgaaaa attttaaaaa acaatgatat actaaacttg tcaaagttgc
       61 aacgggtgct gctacattat gttaaaaatc gctcttgatt gataagctgg atttgttagg
      121 aaaggagtaa ataattatgg ataagaaaaa gatagtttcg actataatat gtatagtatt
      181 tcttgtagtg tcagtagata atttttttag agacttaacc ccgttactgt tcattttaaa
      241 tattattggc ctgtcttgct tttcagtgct aacatacatt aacataaaag agatactctt
      301 aaatataagt aaatgatgat ttggttagtc ctagaaccaa tcaacttatg tttatcggct
      361 tggcagattt tatgtttgtc atttgtttgt atagaggtat ttcagaaaca gaattctatc
      421 aacaactaat cgcttatata ggtgtattct ctgcttgttt atcacgcttc tgctcatgtg
      481 gggcttgaag tattataaaa agtagctttc tatccttttc tgacaggata tttgagtaga
      541 aggctctatt aaattgttag tgaaataaat gaatggaggt atttaatatg aaatacagat
      601 tattttttgt tattttcttg agtagtgtgt tggatattct tttagggaca tttttacaaa
      661 tctctatcgt atctattggg tggcttgttc tttacagtgg tttgtttgaa gtaggagttt
      721 tccttcttgc taataaaggg gtggcggtaa aaatcaagga agtagatatt cgaaatcgct
      781 ttaaatttat ttttggaaaa accttatggt ttcaaattct tttgctcatc tttttgataa
      841 tcaaacttta tcttggtttg gatgcgaggt tgattttatt ctatggacat attttcattg
      901 tctttaatgc cttaatgtat ctattatcta gtagtcaggt tagccttaaa aaaaaacaaa
      961 ctgtcttctt aatcttacag cagtagagtc tgacaaggtg aggtcatagt agggaggatt
     1021 tctatgaaaa agtatcaact tctattcaaa ataagtgcag tcttctctta cttatttttc
     1081 gtatttggtc tttctcagct gacgcttatc gtccaaaatt attggcaatt ttcttcccag
     1141 attggtaatt tcgtctggat tcaaaatatc ttgagtttac tttttattgg agtcatgatt
     1201 gtggttcttg ttaagacagg ccatggttat ctcttccgca ttccaagaaa aaaatggctt
     1261 tggtattcga ttttgacagt attagtggta gtgttccaga tctcttttaa cgttcagaca
     1321 gctaaacatg ttcagtcaac tgcggaaggt tgggctgtat tgattggtta tagtgggact
     1381 aactttgcag agctaggtat ttatatagcc ctgttctttc tggttccact gatggaagaa
     1441 ttgatttata gaggattact gcaacatgct ttctttaagc attcgcgatt tggtcttgat
     1501 ttgcttcttc cttctatttt atttgctctc cctcattttt caagcctgcc tagtctgtta
     1561 gatatcttcg tctttgcaac agttggaatc atctttgctg gtttgacccg ctataccaag
     1621 agcatttatc catcctatgc ggtgcatgtg atcaataata ttgtagcgac cttcccgttt
     1681 ttgctcactt ttctacatag ggtcttgggg taaaaaaaca aaaggcttgc ttttcagcca
     1741 tagaggaggt catcatgtat aaacacttat ttttcctaga ttccaaaact ttagatcggt
     1801 tgacacccta tattctagtc ttggcttctg acaccattgc ttttaatgtt tttgtgctaa
     1861 cctttgtatc tgcggtggtt tttaatttcc taaattccat gctagcttta atggctatat
     1921 tcataggggc tggctatgtg gtcggatttt ggttgctaaa atggtttgtt ttggaaaggt
     1981 tagagctaaa ggatgacgcg taggaagtct gtttggtgag gaggatagtt ttatggagtt
     2041 ttttgataaa tttcatgcct tgtgttttgg atttttagta ctaataattg tcattacagt
     2101 tccttatacg attaaccatg ggggtttttt tcaaaatgaa tctgcattga ttcttgtaag
     2161 tcttcttgta acctcgctga gtgttgctta tgctagaaag tttgaaatga tttcttttgg
     2221 gatgttaagc aagaaacaac ttttgctttt cattgcaatc tttcttctaa gtgtacttga
     2281 gacgctggtt tatattcatt tcttcgctgt ttcttctggc tcaggggtcc aacacttggc
     2341 ggaagtcagc agaggaattt ccctgtcttt gattttgact acctcagttt ttggccccat
     2401 ccaggaggaa ctcattttca gaggacttct tcaaggtgcg gtttttgaca attcttggtt
     2461 agggcttgtg ctaacttcct ctctcttttc tttcatgcat ggaccttcta atgtcccttc
     2521 gtttattttt tatctacttg ggggtttgtt gctgggcttt gcttataaaa agagtcaaaa
     2581 cctatgggtt tctactctag tacacatgtt ttacaacagt tggccactcc tatattattt
     2641 ataaaaatta tgaaaaggta agcagaagac ggtgcttacc tttttcaagc tataatgata
     2701 cccaagccaa tccagaggct tttctttgag aatcgggtta gagtggttga cgaataggcc
     2761 aaaaactagt agaatagtaa ggaaacttta tacggaggaa agaaatggat ttgggtgata
     2821 atgagctaac actgactccc atacctggga aaagtggcaa ggcttatatg ggtagctatc
     2881 ctgacgggaa gcgcatcttt gtaaaaatga acacctctcc aatcctacct ggtctagcta
     2941 gagaacaaat tgctccacaa ttattatgga gtcgtcgttt ggcagatggg cgtgatatgt
     3001 gtgctcaaga atggttgaca ggcaagatat tgacccccta tgatatgaat cgtaagcaaa
     3061 tcgtcaatat tttaacccgt cttcatcgct cacgtccgtt gatgacacaa ttgagtcgtt
     3121 tgggctatgc catggaaaca cctgtagatt tactacagtc ttggcaggaa acggctccag
     3181 atgctttgcg taaaaatcat tttatcagtg aagtgatggc tgatttacgt cagactattc
     3241 caggatttag agaggaccat gcgaccattg tccatggaga tgtacgacat agtaattgga
     3301 ttgagacaga tagtggcttg atttatttag tagattggga ttcggttcgc ttgaccgatc
     3361 gcatgtttga tgtggcccat atgctctgcc attatatttc agaacatcag tggaaggaat
     3421 ggttgaccta ctacggttac aagtacaatc aaacggtatt aagtaaattg tattggtatg
     3481 gtcaattgtc ttatttgagt cagatttcca agtattatat gaaccaagat ttagaaaatg
     3541 tcaatcggga gattcatggt ttgcgtcatt tccgagacaa gtatggaaag agaagatgag
     3601 agttagaaat cgtaaagggg caacagaatt actagaggca aatccccagt atgtggtcct
     3661 caatcccttg gaagccaagg caaaatggcg ggacttgttt ggcaatgata atcccattca
     3721 tgtggaagtt ggaagtggaa agggtgcctt tgtttcaggt atggccaagc aaaaccctga
     3781 catcaactat atcgggattg atattcaaaa gtctgttttg agctacgctt tggacaaggt
     3841 gcttgaagtt ggagtgccta acatcaagct cttgtgggta gatggttctg acttaactga
     3901 ctattttgaa gacggtgaga ttgatcgctt gtatctgaac ttttcagatc catggccgaa
     3961 aaaacgccat gaaaagcgtc gtttgaccta caagaccttc ttggatacct tcaaacgtat
     4021 cttgcctgaa aatggagaaa ttcatttcaa gacggataac cgtggcttgt ttgagtacag
     4081 tttagtgagc ttttctcaat atggcatgaa actcaatggt gtctggttag atttgcatgc
     4141 cagtgatttt gaaggcaatg tcatgacaga atacgagcaa aaattctcaa acaaggggca
     4201 agttatctac cgagttgagg cagaatttta agagatagcc taaaattagg ctgtacaagt
     4261 gcttttgctt tacataagtt ggcaaacgtg ctatactgat agtaagaata tgaaaagtga
     4321 ggcggggaaa tatcttcgcc tcttgcttat gaggaggtgg acgcaatcgc aacaatcgta
     4381 gaattagtca gagaagttgt agaacctgtc atagaagctc cttttgaact cgtggatatc
     4441 gagtatggaa agattggcag tgacatgatt ctcagtattt ttgtagataa acccgaagga
     4501 attaccttga acgacacggc agacttgaca gaaattatca gtcctgtcct agacaccatc
     4561 aagccagatc ccttcccaga acaatatttc ctagaaatta ccagtccagg tttggaacgc
     4621 cctttgaaaa ccaaggatgc cgtcgctgga gcggttggaa aatacatcca tgtcgggctc
     4681 taccaagcca tcgataagca aaaggtcttt gaaggaacct tgttggcctt cgaagaggac
     4741 gagttgacta tggaatatat ggacaagacg cgtaagaaaa ccgtccaaat tccatacagt
     4801 ttagtatcaa aagcacgttt agcagttaaa ttatagaaaa agaaaggata gcttttgagg
     4861 attcaaaagt gaagaaaaca tgagtaaaga aatgctagag gccttccgca ttttggaaga
     4921 agacaaggga atcaaaaaag aagatatcat cgacgcagta gtagagtcgc ttcgttccgc
     4981 ttatcgcaga cgctatggtc agtcagacag cgtagctatt gacttcaacg aaaaaacagg
     5041 tgactttaca gtttatactg tccgtgaagt tgttgatgaa gtatttgata gccgtttgga
     5101 aatcagcttg aaagatgctc ttgccattaa ttcagcttat gaacttggag acaaaatcaa
     5161 gtttgaagaa gcaccagctg agtttggtcg tgtagcagcc cagtctgcca aacaaaccat
     5221 catggaaaaa atgcgcaagc aaacacgtgc catcacttac aatacttaca aagaacatga
     5281 gcaagaaatc atgtctggta cagtagaacg ctttgacaac cgctttatct atgtcaacct
     5341 tggtagcatc gaagcccaat tgtcaaaaca agaccaaatt cctggagaag tttttgcttc
     5401 tcatgatcgt atcgaagttt atgtttacaa ggttgaagac aaccctcgtg gtgtgaacgt
     5461 ctttgttagc cgtagtcatc cagaaatgat caaacgttta atggagcaag aaattccaga
     5521 agtttatgat ggaactgttg aaatcatgag cgtggctcgt gaagcaggtg accgtacgaa
     5581 ggttgctgtt cgtagccaca atccaaacgt ggatgctatc ggtacaatcg ttggacgtgg
     5641 tggtgctaat atcaagaaga ttactagcaa attccaccca gctcgttacg atgctaaaaa
     5701 tgaccgcatg gtaccaatcg aagaaaatat cgatgttatc gagtgggtag cagatccagc
     5761 tgaatttatc tacaatgcca tcgctcctgc tgaggttgac caagttatct ttgatgaaaa
     5821 cgacagcaaa cgtgccttgg tggttgttcc agataacaag ctttctcttg ccattggtcg
     5881 tcgtggacaa aacgtgcgct tggcggctca cttgactggt taccgtatcg atatcaagtc
     5941 tgctagcgaa tttgaagcca tggaagacgc tgcttcagta gagttggaag tagaaaacga
     6001 tactgtagaa gaataaaagc tgctagagga gggaaagatg aaaacaagaa aaatcccttt
     6061 gcgcaagtct gttgtgtcta acgaagtcat tgataagcgt gatttgctcc gcattgtcaa
     6121 gaacaaggaa ggacaagtct ttattgatcc tacgggcaag gccaatggcc gcggcgctta
     6181 tatcaaacta gacaatgcag aagccctaga ggcgaaaaag aagaaggtct ttaaccgcag
     6241 ctttagcatg gaagtggaag aaagctttta tgacgagttg atcgcttatg tggatcacaa
     6301 agtgaaaaga agagagttgg gacttgaata agcaaaagat aagtaatctc ttggggcttg
     6361 ctcagcgagc agggcgcatc atatcgggtg aagaattggt ggtcaaggcc attcaagacg
     6421 gcaaggccaa gttggtcttt ctagctcatg atgctggacc caatctgacc aagaagattc
     6481 aagataaaag tcattattat caagtagaaa ttgtaaccgt gttttcaaca ctggaattaa
     6541 gcatagcagt cgggaaatcg agaaaggttt tggctgtaac agatgctgga tttacaaaga
     6601 aaatgaggtc tcttatggaa tagaagagga ggacatgatt tgtctaagaa aagattgtac
     6661 gaaatcgcaa aagaacttgg aaaagaaagt aaagaagttg tagcgcgtgc aaaagagttg
     6721 ggcttggatg tgaaaagcca ctcatcaagt gtggaagaag ctgtcgctgc aaaaattgct
     6781 gccagcttta agcctgcagc tgctccgaaa gtagaagcaa aacctgcagc accaaaagta
     6841 agtgcagaaa agaaagccga aaaatctgag ccagctaaac cagctgtagc taaggaagag
     6901 gcaaaaccgg ctgagccagt tgctccgaaa acagaaaaag tagcagtgaa accgcaaagt
     6961 cgtaatttca aggctgagcg tgaagcccgt gctaaagagc aggcagaacg acgcaagcaa
     7021 aataagggca ataaccgtga ccaacaacaa aacggaaacc gtcagaaaaa cgacggccgt
     7081 aatggtggaa aacaaggtca aagcaaccgc gacaatcgtc gctttaatga ccaagctaag
     7141 aagcagcaag gtcagcaaaa acgtagaaat gagcgccgtc agcaagagga taaacgttca
     7201 aatcaagcgg ctccacgtat tgactttaaa gcccgtgcag cagccctaaa agcagagcaa
     7261 aatgcagagt acgctcgttc aagtgaggaa cgcttcaagc agtatcaggc tgctaaagaa
     7321 gccttggctc aagctaacaa acgcaaggaa ccagaggaaa tctttgaaga agcggctaag
     7381 ttagctgaac aagcacagca agttcaagca gtggttgaag tcgtccctga gaaaaaagaa
     7441 cctgcagtgg atacacgtcg taaaaaacaa gctcgaccag acaaaaatcg tgacgattat
     7501 gatcatgaag aagatggtcc tagaaaacaa caaaagaatc gaagtagtca aaatcaagtg
     7561 agaaatcaaa agaatagtaa ctggaataac aacaaaaaga acaaaaaagg caataacaag
     7621 aacaaccgta atcagactcc aaaacctgtt acggagcgta aattccatga attgccaaca
     7681 gaatttgaat atacagatgg tatgaccgtt gcggaaatcg caaaacgtat caaacgtgaa
     7741 ccagctgaaa tcgttaagaa acttttcatg atgggtgtca tggccacaca aaaccaatcc
     7801 ttggatgggg aaacaattga actcctcatg gtggattacg gtatcgaagc caaacaaaag
     7861 gttgaagtgg ataatgctga catcgaacgt ttctttgtcg aagatggtta tctcaatgaa
     7921 gatgaattgg ttgagcgtcc accagttgtt actatcatgg gacacgttga ccacggtaaa
     7981 acaacccttt tggatactct tcgtaactca cgtgttgcga caggtgaagc aggtggtatt
     8041 actcagcata tcggtgccta ccaaatcgtg gaaaatggta agaagattac cttccttgat
     8101 acaccaggac acgcggcctt tacatcaatg cgtgcgcgtg gtgcttctgt taccgatatt
     8161 acgatcttgg tcgtagcggc agatgacggg gttatgcctc agactattga agccatcaac
     8221 cactcaaaag cagctaacgt tccaatcatc gtagccatta acaagattga taaaccaggt
     8281 gctaacccag aacgcgttat cggtgaattg gcagagcatg gtgtgatgtc aaccgcttgg
     8341 ggtggagatt ctgaatttgt tgaaatctca gctaaattca accaaaatat cgaagaattg
     8401 ttggaaacag tccttcttgt agctgaaatc caagaactca aggcagaccc aacagtgcgt
     8461 gcaatcggta cggttatcga agcgcgcttg gataaaggaa aaggtgcggt cgcaaccctt
     8521 cttgtacaac aaggtacctt gaatgttcaa gacccaatcg ttgtcggaaa taccttcggt
     8581 cgtgtccgtg ctatgaccaa cgaccttggt cgtcgtgtta aagttgctgg accatcaaca
     8641 ccagtctcta tcacaggttt gaacgaagca ccgatggcgg gtgaccactt tgccgtttac
     8701 gaggatgaaa aatctgcgcg tgcagcaggt gaagagcgtg ccaaacgtgc cctcatgaaa
     8761 caacgtcaag ctacccaacg tgttagcctt gaaaacctct ttgataccct taaagctggg
     8821 gaactcaaat ctgttaatgt tatcatcaag gctgatgtac aaggttctgt tgaagccctt
     8881 tctgcctcac ttcaaaagat tgacgtggaa ggtgtcaaag tgactatcgt ccactcagcg
     8941 gtcggtgcta tcaacgaatc agacgtgacc cttgccgaag cttcaaatgc ctttatcgtt
     9001 ggtttcaacg tacgccctac accacaagct cgtcaacaag cagaagctga cgatgtggaa
     9061 atccgtcttc acagcattat ctacaaggtt atcgaagaga tggaagaagc tatgaaaggg
     9121 atgcttgatc cagaatttga agaaaaagtt attggtgaag cggttatccg tgaaaccttc
     9181 aaggtgtcta aagtgggaac tatcggtgga tttatggtta tcaacggtaa ggttgcccgt
     9241 gactctaaag tccgtgttat ccgtgatggt gtcgttatct atgatggtga actcgcaagc
     9301 ttgaaacact ataaagacga cgttaaggaa gttacaaacg gccgtgaagg tggattgatg
     9361 atcgacggct acaatgatat taagatggat gatgtgattg aggcgtatgt catggaagaa
     9421 atcaagagat aagatttttt gctcctttct taggtggtga gggacgcaag caaaccgatg
     9481 gtttcattgc ttatttttga gcctagggtc tcaaaaatcc cctgtgatgg gactgataaa
     9541 tcagttccat cactttcacc acggcgaaag aagcagatga cttcaaattg aacttcgttt
     9601 caatttaaac tgaaaatcaa gaagtttaaa atagctaggt ctgctggcct agcttttggt
     9661 tcaaagtaga gaaaggaata tcatggcaaa tcatttccgt acagatcgtg tgggcatgga
     9721 aatcaagcgt gaagtcaatg agattttgca aaagaaagtc cgtgatccac gtgtccaagg
     9781 tgtgaccatc acagatgttc agatgctggg tgacttgtct gttgccaagg tttattacac
     9841 cattttgagt aaccttgctt cggataacca aaaagcccaa atcgggcttg aaaaagcaac
     9901 tggtaccatc aaacgtgaac ttggtcgcaa tttgaaattg tacaaaatcc cagatttgac
     9961 cttcgtcaaa gacgagtcca tcgagtatgg aaacaagatt gacgagatgc tacgcaatct
    10021 ggataagaac taaagaagag gggttgcccc tctttttcgg ctctttgtca actgtagtgg
    10081 gttgaagaaa agctaagctc gagaaaggac aaattt
//
LOCUS       DAVBDR010000068        10036 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.068, whole genome shotgun sequence.
ACCESSION   DAVBDR010000068 DAVBDR010000000
VERSION     DAVBDR010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10036)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10036)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10036
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.068"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            complement(103..1806)
                     /gene="ilvD"
                     /locus_tag="VQ540_001851"
     CDS             complement(103..1806)
                     /gene="ilvD"
                     /locus_tag="VQ540_001851"
                     /EC_number="4.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="HET2545609.1"
                     /translation="MTELDKRHRSSIYDSMVKSPNRAMLRATGMTDKDFETSIVGVIS
                     TWAENTPCNIHLHDFGKLAKEGVKSAGAWPVQFGTITVADGIAMGTPGMRFSLTSRDI
                     IADSIEAAMSGHNVDAFVAIGGCDKNMPGSMIAIANMDIPAIFAYGGTIAPGNLDGKD
                     IDLVSVFEGIGKWNHGDMTAEDVKRLECNACPGPGGCGGMYTANTMATAIEVLGMSLP
                     GSSSHPAESADKKEDIEAAGRAVVKMLELGLKPSDILTREAFEDAITVTMALGGSTNA
                     TLHLLAIAHAANVDLSLEDFNTIQERVPHLADLKPSGQYVFQDLYEVGGVPAVMKYLL
                     ANGFLHGDRITCTGKTVAENLADFADLTPGQKVIMPLENPKRADGPLIILNGNLAPDG
                     AVAKVSGVKVRRHVGPAKVFDSEEDAIQAVLTDEIVDGDVVVVRFVGPKGGPGMPEML
                     SLSSMIVGKGQGDKVALLTDGRFSGGTYGLVVGHIAPEAQDGGPIAYLRTGDIVTVDQ
                     DTKEISMAVSEEELEKRKAETTLPPLYSRGVLGKYAHIVSSASRGAVTDFWNMDKSGK
                     K"
     gene            complement(2039..2971)
                     /locus_tag="VQ540_001852"
     CDS             complement(2039..2971)
                     /locus_tag="VQ540_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HET2545610.1"
                     /translation="MMRSTKELRHVYRDFLLEANQSDSDIVVLEADLSSSMATNNLEK
                     DFGDRYVNVGIMEAEMVGLAAGLSIQGFRPYLHTFGPFASRRVFDQLFISLGYAQLDA
                     TVIGSDAGVTAEMNGGTHMPFEEIGLLRLIPKSIIFEATDDIQFREILNQTLDLKGLK
                     YIRTIRKAPVPVYQGGEDFSKGYIELRHGEDLVIVASGIMVAPSIRVADELSKLGYSV
                     GVIDLFRIKPIPEQIKTMLSGKTIFTVENHNQIGGIGSALCELFSDDGITKIHRMGVQ
                     ERFGQVGKMDYLLNEYGLSESNIKEKVLEIYNAR"
     gene            complement(2968..3825)
                     /locus_tag="VQ540_001853"
     CDS             complement(2968..3825)
                     /locus_tag="VQ540_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HET2545611.1"
                     /translation="MILSKNREDGLRKFATNIRLNTLRTLNHLGFGHYGGSLSIVEVL
                     AVLYGEIMPMTPEIFAARDRDYFILSKGHGGPALYSTLYLNGFFDKEFLYSLNTNGTK
                     LPSHPDRNLTPGIDMTTGSLGQGISVATGLAYGQRIRKSPFYTYAIVGDGELNEGQCW
                     EAIQFASHQQLSNLIVFVDDNKKQLDGFTKDICNPGDFVEKFSAFGFESIRVKGSDIR
                     EIYEGIVQLKQSNNSSPKCIVLDTIKGQGVQELEEMKSNHHLRPTVEEKQMLTSVVER
                     LSQELEETE"
     gene            complement(3829..5175)
                     /locus_tag="VQ540_001854"
     CDS             complement(3829..5175)
                     /locus_tag="VQ540_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000975284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HET2545612.1"
                     /translation="MMKFILDIVSTPAILVALIAILGLVLQKKKLPDIIKGGIKTFVG
                     FLVVSGGAGIVQNSLNPFGTMFEHAFHLSGVVPNNEAIVAVALTTYGSATAMIMFAGM
                     VFNILIARFTRFKYIFLTGHHTLYMACMIAVILSVAGFTSLPLILLGGLALGIIMSIS
                     PAFVQKYMVQLTGNDKVALGHFSSLGYWLSGFTGSLIGDKSKSTEDIKFPKSLAFLRD
                     STVSITLSMAVIYIIVAIFAGSEYIEKEISSGTSGLVYALQLAGQFAAGVFVILAGVR
                     LILGEIVPAFKGISERLVPNSKPALDCPIVYTYAPNAVLIGFISSFVGGLVSMVIMIA
                     SGTVVILPGVVPHFFCGATAGVIGNASGGVRGATIGAFLQGILISFLPVFLMPVLGGL
                     GFQGSTFSDADFGLSGIILGMLNQFGSQAGIVIGLVLILAVMFGVSFIKKPSATEE"
     gene            complement(5188..5472)
                     /locus_tag="VQ540_001855"
     CDS             complement(5188..5472)
                     /locus_tag="VQ540_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET2545613.1"
                     /translation="MLKIGTACGSGLGSSFMVQMNIESVLSDLNVSDVEVEHYDLGGA
                     DPNAADIWIVGRDLADSASHLGDVRILNSIIDMDELRELITKLCEEKGLI"
     gene            complement(5476..7506)
                     /locus_tag="VQ540_001856"
     CDS             complement(5476..7506)
                     /locus_tag="VQ540_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000460919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HET2545614.1"
                     /translation="MFDYRALVILMTLMDHCELSLYELSVKVSLPIKEVKEGIDYLVP
                     YLANKGIVLDKKQGRYSLSNRTKQSLTDIIKSDELVLPKSTRLALIYLYTFCRLDFIS
                     NSHYQDFLKVSKNTTLSDIQSLRKIMLDNDLELGYSRAKGYTLHGSEWNKHRLAFQMV
                     SELLESSIGIWGLDYVLSSWGYSLTYDLIDQVVKDYYEKLQLVPIVNQLKVYLFGLVF
                     ILCRYQRDVERVCLSETLVSPVIQDITTILLDTVVDLGIIDTVFSEDDYRYITVLLSS
                     CFEGEVDVAPVYFNQLTEAIISRMEDISLLHFKQREGLRENLRRHLIPAYYRLKFGLP
                     SSNEYVLHVKEHYPDLFELVKDSLMPLMDAIDNPIPDSETAYFVIHFGGYLKKADTLP
                     QKWYKAAIICPNGVSSSLMLKENLLALFPQIEFIGTSKIDDLQVKASSDYDMVFSTIK
                     VETEKPNYLVSVMMTEEQAIQLVELVLKDFPNLEYGDFEIEQILNIVKRYGIITQELE
                     LRLALKNYLYQKNDRKEIVPVLEQLITKETYQVSSQKLGWKEAIRLAAKPLLDQDKIT
                     ENYPEAMIQKVEEFGPFINLGKGVAIPHARPDEGVNEIGMSMLVLEEPIYLLDNPEQE
                     VRLLICIAAIDNESHLKALSHLTTILRDKNHVQTLISSKNYDDIKMIIKQED"
     gene            7698..8705
                     /locus_tag="VQ540_001857"
     CDS             7698..8705
                     /locus_tag="VQ540_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HET2545615.1"
                     /translation="MTEKLINSKPNGVFALILIELTIVLGIFIFIMGVGSENIFGIII
                     GPLLIVIAGLAHAGLKVVKPQEALVLTLFGNYTGTIKEPGFYFVNPFSVAVNPANHTR
                     LGQSGDVSTKSPFLGAKSSNDNDVNLEIGKKQISLKVMTLSNSRQKINDCLGNPVEIG
                     IAVTWRVVDTAKAVFNVDNYKEYLSLQCDSALRNIVRIYPYDVSPNVDTTGDGQADEG
                     SLRGSSEIVANRIREEIQSRVEDAGLEILEARITYLAYAPEIAAVMLQRQQASAIIDA
                     RKMIVDGAVGMVEMALERLNEGELVELDEERKAAMVSNLLVVLCGNHDAQPIVNTGSL
                     Y"
     gene            8708..8908
                     /locus_tag="VQ540_001858"
     CDS             8708..8908
                     /locus_tag="VQ540_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HET2545616.1"
                     /translation="MAEAKKKQIPLRLSTKLYAALASWAEDDFRSVNGQIEYLLTECV
                     KQRKKDGKYVSETIDEPFEIDI"
     gene            9060..9242
                     /gene="rpmF"
                     /locus_tag="VQ540_001859"
     CDS             9060..9242
                     /gene="rpmF"
                     /locus_tag="VQ540_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HET2545617.1"
                     /translation="MAVPARRTSKAKKNKRRTHYKVTAPSVNFDETTGDYSRSHRVSL
                     KGYYKGRKITKAASAE"
     gene            9258..9407
                     /gene="rpmG"
                     /locus_tag="VQ540_001860"
     CDS             9258..9407
                     /gene="rpmG"
                     /locus_tag="VQ540_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001265622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HET2545618.1"
                     /translation="MRVNITLEHKESGERLYLTSKNKRNTPDRLQLKKYSPKLRKHVV
                     FTEVK"
     gene            complement(9899..>10036)
                     /locus_tag="VQ540_001861"
     CDS             complement(9899..>10036)
                     /locus_tag="VQ540_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000753868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HET2545619.1"
                     /translation="ESGSMATGWVTVSGKWYYTYNSGDLLVNTTTPDGYRVNANGEWV
                     G"
BASE COUNT         3252 a         2132 c         1626 g         3026 t
ORIGIN      
        1 caaaacactg ttttgaggtt gtggatagaa ctgacgaagt cagtaaccat acctacggca
       61 aggcgacgtt gacgtgattt gaagagattt tcgagtatga gtttattttt tacctgactt
      121 gtccatattc cagaagtctg tcacggctcc gcgtgaagca gatgatacga tgtgggcata
      181 tttaccgagg acaccacggc tgtaaagtgg tggcaaggtt gtttctgcct tgcgtttttc
      241 aagttcttct tcggatacgg ccatagaaat ttctttggta tcttggtcaa ccgtaacgat
      301 atcgccggta cggagatagg caattggtcc accatcctga gcttcaggag cgatatgtcc
      361 aacaaccaga ccataagtac caccagagaa acgtccgtcc gtcaagaggg ccaccttatc
      421 tccctgacct ttaccaacaa tcattgaaga aagtgatagc atctcaggca taccaggacc
      481 acctttaggt ccaacaaaac gaacaacgac tacatcgcca tcaacgattt catctgtcag
      541 aacggcctga atcgcatctt cttctgagtc aaagacctta gctggcccaa cgtgacgacg
      601 cactttaaca cctgatacct tggcaactgc accgtcagga gcaaggttcc cgttcaagat
      661 gataagcgga ccatccgcac gttttggatt ttcaagtggc atgataactt tttggcctgg
      721 agtcaagtct gcaaagtcag ccaagttttc agctacagtc ttaccagtac atgtgatgcg
      781 atctccgtga aggaaaccat ttgccaacaa atacttcata accgcaggga caccaccgac
      841 ttcgtagagg tcttggaaga catactgacc agatggtttc aagtcggcca agtgaggcac
      901 acgttcttga atcgtattga agtcctcaag tgacaagtca acatttgcgg catgggcaat
      961 ggcgagcaag tgaagagtgg cgtttgtaga accaccgaga gccatcgtta cagtgatagc
     1021 atcttcaaag gcttcacgag tcaagatatc tgatggtttg agaccaagtt ccaacatctt
     1081 aacaacagca cgtcctgctg cttcgatatc ttctttctta tcagctgatt cagctgggtg
     1141 agaggatgac cctggcaaac tcatccctag aacttcgata gcagttgcca tggtattagc
     1201 agtatacata ccaccacaac caccagggcc agggcaggca ttacattcaa gacgtttcac
     1261 gtcctcagct gtcatgtcac cgtggttcca ttttccgata ccttcaaaga cagaaaccaa
     1321 gtcgatatct ttaccatcaa gatttcccgg tgcaatagtt ccaccatagg cgaaaatagc
     1381 tgggatatcc atattagcaa tagcaatcat agatccaggc atgttcttgt cacagccacc
     1441 gatagcgacg aaggcatcca cgttgtgacc actcatagcc gcctcgatgg agtccgcgat
     1501 gatgtcacga gatgttagag agaaacgcat accaggcgtt cccatagcga tcccgtccgc
     1561 tacggtaatg gttccaaact gtacaggcca agcgcctgca gatttgacac cttctttagc
     1621 cagtttcccg aaatcatgca agtgaatgtt acatggtgta ttttccgccc aagtcgaaat
     1681 cactcccaca atcgatgttt caaagtcctt atctgtcata ccagtcgcac gaagcatagc
     1741 acggttaggt gatttaacca tgctgtcata aatgctactg cggtgacgtt tatctaattc
     1801 agtcatctta tccctcccat ttcagttttt actattatag cacaattttc gcatgaagaa
     1861 cagaataaaa ttcttgaatt ttcagaaaat tctatacaca tgtgaaatat ttaaaattaa
     1921 aaacaacaaa gcggattagt gcactttctg atgaccagaa tatgcttttt aatccgcttt
     1981 ctttaaataa cgtactgtaa tttttacaga aattctttca aataagtgta tttaacatct
     2041 atcttgcatt ataaatttct agaaccttct cttttatatt cgattcactc aaaccatact
     2101 cattaagaag ataatccatt ttccctactt gaccgaatct ttcttgaaca cccatccgat
     2161 gaatttttgt tattccatca tcagagaata attcacataa agcactgcca attccaccta
     2221 tctgattgtg gttttctaca gtaaatatag tttttccact taacattgtt tttatctgtt
     2281 ctggtatcgg tttgattcta aataaatcta tcacacctac tgaataacct aatttagaca
     2341 gttcatctgc aactcgaata cttggagcaa ccattatgcc agaagcaacg attacaagat
     2401 cttcaccatg ccttaactca atgtagcctt tagaaaaatc ttctccacct tgatacacag
     2461 gaactggagc ttttctaatt gttcgaatat attttagtcc ttttaagtct aatgtctggt
     2521 tcaatatttc acgaaattgg atatcatcag ttgcttcgaa aatgattgat ttaggaatta
     2581 aacgtaacaa tccaatttct tcaaatggca tatgtgttcc accattcatc tctgccgtta
     2641 ctcctgcatc tgatccaatc acagtggcat ccaattgtgc gtatccaaga gaaataaata
     2701 attgatcaaa tactcttcgt gaagcaaaag gaccaaatgt atgaagataa ggtctaaacc
     2761 cctgaataga caagcctgct gcaaggccga ccatttctgc ttccataatc ccaacattca
     2821 cataacggtc tccaaagtcc ttttcaagat tattagtagc catcgaactt gacaaatcgg
     2881 cttctaagac tactatatca gaatcacttt gattagcctc taaaaggaag tctctatata
     2941 catgccgtaa ttctttcgta cttctcatca ttctgtttcc tccaattcct gacttaatct
     3001 ttctacaact gaagttaaca tttgtttctc ctctacagta gggcgaagat gatgattgga
     3061 tttcatttct tccagctctt gaaccccttg acctttaata gtatctaata caatgcactt
     3121 aggtgatgaa ttatttgact gttttaattg gacaatccct tcataaattt ctctaatatc
     3181 tgaacccttg accctaatgg attcaaatcc aaatgctgaa aatttttcta cgaaatcacc
     3241 tggattacaa atatcctttg taaaaccatc taattgtttt ttgttatcat caacaaatac
     3301 aattaagttg gataactgtt gatgagaagc aaactgtata gcctcccaac attgtccctc
     3361 atttaactca ccatctccaa caatagcgta agtataaaag ggactctttc ttattctctg
     3421 accatatgca agtccagttg caacactaat tccttgtcct aaagagcccg ttgtcatatc
     3481 tatgcctggc gttagatttc tatcaggatg agacggtaat ttggttccat ttgtatttaa
     3541 agaatataag aattctttgt caaagaaacc attcaaatag agtgtactgt atagagctgg
     3601 tcctccgtga ccttttgata atatgaaata atctctatct cgtgctgcaa atatttctgg
     3661 agtcattggc attatttcac cataaagcac cgctaaaact tctacgatag acagacttcc
     3721 tccgtaatgt ccgaatccaa gatgattcaa tgttctaaga gtatttaatc ggatgttagt
     3781 cgcaaatttt cttaacccat cttctctatt tttacttaaa atcatccctt attcctccgt
     3841 tgcagatggc tttttaataa aggatactcc aaacataact gctagaataa gaacaagacc
     3901 aatcacaatg cctgcttgtg agccaaattg atttaacatt cctaaaataa ttcctgatag
     3961 accaaaatct gcatctgaga aagttgatcc ttggaaacca agtcctccca aaactggcat
     4021 taaaaagact ggaagaaaac tgattaaaat accttgtaaa aatgctccaa tagtggctcc
     4081 acgaacacca ccagatgcat tcccaatgac acctgcagtc gctccacaga agaaatgagg
     4141 cacaacacct ggtaagataa caaccgttcc tgaagcaatc ataattacca tacttactaa
     4201 accaccaaca aaactagaga taaatccaat tagaactgca ttgggtgcat aagtataaac
     4261 aatcggacaa tccaaagcag gttttgaatt aggtacaaga cgctctgaaa tacctttaaa
     4321 ggctggaaca atttcgccca aaataaggcg aacacctgct aaaataacaa atacccctgc
     4381 tgcaaattga cctgctaatt gtaaagcata aactagacca cttgtaccac tactgatttc
     4441 tttttctata tattctgacc ctgcaaagat agctacaata atgtaaataa ctgccatgga
     4501 taaagtaata ctaacagtac tatcacgtaa aaaagctaaa ctctttggaa atttaatgtc
     4561 ctctgttgat tttgatttgt caccgataag gctaccagta aaaccactca accaatatcc
     4621 caaagaactg aaatgaccta aagctacctt gtcatttcca gttaattgaa ccatatattt
     4681 ttgcacaaat gctggggaaa tactcataat aataccgagt gctaatcctc ctagtaagat
     4741 gagaggcaag ctagtaaagc cagcaactga taaaatgacc gcaatcatac atgccatata
     4801 tagagtgtgg tgccctgtta aaaaaatata tttaaatcga gtaaaacgag cgattaagat
     4861 attgaacacc atgcctgcaa acataatcat tgcagtagct gagccatatg ttgttaaagc
     4921 tacagctaca attgcttcat tattcggcac aacgccagat aaatgaaaag catgctcaaa
     4981 catggtacca aatggattta aagaattttg tacaattcct gcaccaccag atacaactaa
     5041 gaaaccaaca aaggtcttaa ttccaccttt aataatatca ggtaatttct tcttctgaag
     5101 aactaatcct aagattgcaa ttaaagctac taaaatagct ggtgtactaa caatatccaa
     5161 tatgaacttc atcatgacgc tagcctccta tataagtcct ttttcttcac aaagtttagt
     5221 aattaattct cgtagttcat ccatatcaat aatactattt aagatacgaa catctccaag
     5281 atgactagct gaatcagcta gatcacgacc aacaatccaa atatcagctg catttggatc
     5341 tgctccacct aaatcataat gttcaacttc tacatccgaa acattcaaat cactcaatac
     5401 agattcaata ttcatctgta ccataaaact tgaacctaat cctgaaccac aagctgtacc
     5461 aatttttaac attatctaat cctcctgttt aattatcatt ttaatgtcat catagttttt
     5521 tgatgatatt aaagtttgaa catgattttt atctcttaaa attgttgtta aatgtgacaa
     5581 agcctttaaa tgactctcat tatcaatggc tgcaatacaa atcaacaatc ttacctcttg
     5641 ttctggatta tccaataaat aaatcggttc ttccaaaact aacattgaca ttcctatttc
     5701 attcacacct tcatctggcc gagcgtgagg aattgctact cccttcccta aattaataaa
     5761 aggtccaaac tcttctactt tttgaatcat tgcctcaggg tagttctcag ttatcttatc
     5821 ttgatccaaa agcggtttag ctgctaaacg aatcgcctcc ttccatccta atttttgcga
     5881 actaacctga taggtttctt tggtaataag ttgttctagc actggtacaa tttcctttct
     5941 atcatttttt tggtaaagat aattctttaa cgccaatctt aattccaatt cttgtgtaat
     6001 aattccatat cttttgacaa tattcaggat ttgttcaatc tcaaaatctc catactctaa
     6061 attcggaaaa tcttttaaca ctagttctac tagttgtatt gcttgctctt cagtcatcat
     6121 aaccgaaact agataatttg gcttttctgt ctccaccttt atggtagaaa aaaccatatc
     6181 atagtcacta ctagctttca cctgtaaatc atcaatcttt gaggttccta taaactcaat
     6241 ttgaggaaat aatgctaata gattctcttt taacatcaat gaagaactaa caccattagg
     6301 acaaatgatt gctgctttat accatttttg aggcaaagta tctgctttct ttaaataacc
     6361 tccgaaatgg ataacaaaat atgctgtttc actatcaggt atgggattgt caatagcgtc
     6421 catcaagggc atcaaagaat ctttgactaa ttcaaataaa tcaggataat gttctttaac
     6481 atgcaataca tattcatttg aactaggtag gccgaacttt aatctatagt aagccggtat
     6541 aaggtggcgg cgaagatttt ctctcaatcc ttccctttgt ttaaaatgta acaaagaaat
     6601 atcttccatt ctacttataa tagcctctgt taattgatta aagtaaaccg gagcaacatc
     6661 tacttcacct tcaaagcaac ttgataataa aacggtgata tagcgataat catcctcaga
     6721 aaacaccgta tctataattc ccaaatcaac cactgtatcc aataaaatag tggttatatc
     6781 ttgaataaca ggagatacta atgtctctga aagacatact ctttcaacat ccctttgata
     6841 cctacacaga atgaatacta aaccgaaaag gtaaactttt aattgattaa caataggtac
     6901 tagctgtagc ttctcataat aatctttaac tacctgatca atcaaatcat aagttaatga
     6961 atacccccaa ctggataaaa cataatccaa accccaaatc cctatggagg attccagcaa
     7021 ctcactaacc atttgaaaag ctaagcggtg cttattccac tctgaaccgt gtaaagtata
     7081 accttttgct ctactgtacc ctagctccaa atcattatct aacataatct ttcttaatga
     7141 ttgaatatca gataaggttg tattcttact tactttcaaa aagtcttggt aatgactatt
     7201 cgatataaaa tctaatcggc aaaaagtgta aagatagatt aaagctaagc gagtcgactt
     7261 tggtaaaacc aattcatccg acttaataat atctgtcaaa gactgcttcg tacgatttga
     7321 taaactatag cgaccttgct ttttatccag cactatccct ttattagcta gataaggcac
     7381 taaataatct attccttctt tgacttcctt tataggtaag ctcaccttaa cagataattc
     7441 atataatgat agctcacaat gatccatcaa agtcatcaaa ataactagtg ctctataatc
     7501 aaacatttct cttcctttct aactacaatt atagtgtaaa aattataaga ataaaagagt
     7561 atttgagcac aatataatct caccttttaa aagaaattat tgggctgaaa gtttttagtg
     7621 attatttttc aactttctat tgactttata aattaaagtg atatcattta gatatcaaat
     7681 aacaggaggt cattcttatg actgaaaaac taatcaattc aaaaccaaat ggtgtattcg
     7741 cattgattct cattgagttg acaatcgtac ttggtatctt tatatttata atgggggttg
     7801 gttcggaaaa catttttgga attattatcg gacctttact aatcgtaatt gcaggtctag
     7861 ctcatgctgg tttaaaagtt gtcaaacctc aagaagctct ggttctgaca ctctttggta
     7921 actatacagg taccatcaaa gaacctggct tttactttgt caatcccttc agcgtagcag
     7981 tcaaccctgc aaaccacact cgacttggac aaagtggtga tgttagcaca aaatctcctt
     8041 ttttaggagc taaatcatca aatgacaatg atgtaaatct tgaaattggc aagaaacaga
     8101 tttccctcaa agtcatgacc ttgagcaatt ctcgtcaaaa aatcaatgat tgcttaggaa
     8161 accctgtaga aatcggtatc gcggtaactt ggagagttgt cgataccgct aaggcagtct
     8221 tcaacgttga taactacaaa gaatatcttt cattgcaatg tgatagcgcc ctccgtaata
     8281 ttgtccgcat ctatccttac gatgtgtctc ctaatgtgga tactacgggt gatgggcaag
     8341 cagatgaagg tagtctccgt ggctctagcg aaattgttgc taaccgtatt cgtgaagaaa
     8401 tccaaagtcg tgttgaggat gctggcttgg aaatccttga agcacgtatc acttacctag
     8461 cttatgctcc agaaattgct gccgttatgc ttcaacgcca acaagcatct gccattattg
     8521 atgcacggaa gatgattgta gatggtgctg taggaatggt tgaaatggca ctagaacggc
     8581 tcaatgaagg ggaattggta gaacttgacg aagaacgaaa agctgccatg gtttcaaatc
     8641 tccttgtcgt tctttgtggc aatcatgatg cacaaccaat tgtcaacaca ggaagccttt
     8701 actaaagatg gctgaagcta aaaaaaagca gatccccctt cgactctcaa caaagttata
     8761 cgctgcactc gcatcatggg cagaagacga ctttcgttca gtcaatgggc aaatcgaata
     8821 tctcctcaca gagtgtgtca agcaacggaa gaaagacgga aaatacgtat cagaaaccat
     8881 tgacgaacca tttgagattg atatttaaca ccttctcctg tctgccgtgt cggataggag
     8941 aattttttca tctttttttg tcaagtaact ttactttaca aaaaaaatgt gttatcctag
     9001 tatggttgat gaaaatcagt agattgaatc gaatataaat acctaaagga gaaatcaaaa
     9061 tggcagtacc tgcacgtcgc acttcaaaag cgaagaaaaa caaacgtcgt acacactaca
     9121 aagtaacagc tccatctgta aactttgacg aaactactgg agattactca cgttctcacc
     9181 gtgtatcact taaaggatac tacaaaggac gtaaaatcac taaagctgca tcagctgaat
     9241 aatagaaggg agataccatg cgcgtaaata ttacacttga acacaaagaa tctggtgaac
     9301 gcttgtacct tacttctaaa aacaaacgta acactccaga ccgccttcaa ttgaagaaat
     9361 actcaccaaa acttcgcaaa cacgttgtgt ttacagaggt taaataagca ttcaatacga
     9421 atcaatacag aagaaaaacg cttgatcagc gttttttctt tttgttaatt tcactacatt
     9481 gtaagggaaa tcattcgaat gactacattt ttcactacct tttttgaaat aagaatacgg
     9541 attcggacaa ttaaaagcaa gaggaactca aatgtaagtt ggggttcctt ttttgtatat
     9601 ttttcaaata acgcctctac actatttgta gcaaattcac caactacagt tgtatcttag
     9661 ttaaaataag ttagaatatg taagtgagta ccagatatac caagacatcg tcaccatcta
     9721 aggtatattc aaaatacaaa agttgaccaa ctagatttct gaatatcctt atatatccat
     9781 tcttaaaatt ggtttaaata gcgtagtctt ttaaactagt tttgagaatc caaaaaatct
     9841 tcctacatat gtaagaagat tttttagttc agaatgatta gatttagcta atggatacct
     9901 atcctaccca ctcaccgtta gcattgactc gatagccatc gggtgtagtc gtgtttacta
     9961 ataaatctcc tgaattatag gtatagtacc atttaccaga aactgtaacc caaccagtag
    10021 ccattgaacc tgattc
//
LOCUS       DAVBDR010000069         9472 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.069, whole genome shotgun sequence.
ACCESSION   DAVBDR010000069 DAVBDR010000000
VERSION     DAVBDR010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9472)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9472)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9472
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.069"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            150..686
                     /locus_tag="VQ540_001862"
     CDS             150..686
                     /locus_tag="VQ540_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000709035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HET2545620.1"
                     /translation="MKKAHVYAIPAIGAALIAALAQISLPIGPVPFTLQNFAIGLIAT
                     VFRPREAVLSAGLYLLLGAIGLPVFAGGGAGFQALVGPTAGYLWFYLVYSGLTSSLTN
                     SKSGVVKIFLANLLGDALVFVGGILSLHFLAGMAFEKALAVGVLPFIIPDLGKLLAIS
                     FISRPLLQRLKNQAYFTN"
     gene            737..823
                     /locus_tag="VQ540_001863"
                     /pseudo
     CDS             737..823
                     /locus_tag="VQ540_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(892..1107)
                     /locus_tag="VQ540_001864"
     CDS             complement(892..1107)
                     /locus_tag="VQ540_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000807422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HET2545621.1"
                     /translation="MAEFTFEIEEHLLTLSENEKGWTKEINRVSFNGAPAKFDIRAWS
                     PDHTKMGKGITLSNEEFQTMVDAFKGN"
     gene            1205..1525
                     /locus_tag="VQ540_001865"
     CDS             1205..1525
                     /locus_tag="VQ540_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001216095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2545622.1"
                     /translation="MRHKFQQVLNKIHDFLNGYDQPDQTETNSLTATIEEAIQKQTAV
                     HLILSETSFTGDIIKYDQQGQQIIVKNFAKNVSRIIRISDIQRLRFVPSTVQTAQKNR
                     FKKE"
     gene            complement(1556..1894)
                     /locus_tag="VQ540_001866"
     CDS             complement(1556..1894)
                     /locus_tag="VQ540_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2545623.1"
                     /translation="MQVIKRNGEIAEFNPDKIYQAILKAAQTVYVLTDDLRQNLAQVT
                     KKVVLDLQEAKVERATISMIQSMVEHRLLGAGYITIAEHYISYRLQRDLERSGYGDHI
                     AVHLHFEQIR"
     gene            complement(1906..2625)
                     /gene="trmD"
                     /locus_tag="VQ540_001867"
     CDS             complement(1906..2625)
                     /gene="trmD"
                     /locus_tag="VQ540_001867"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HET2545624.1"
                     /translation="MKIDILTLFPEMFSPLEHSIVGKAREKGLLDIQYHNFRENAEKA
                     RHVDDEPYGGGQGMLLRAQPIFDSFDAIEKKNPRVILLDPAGKQFDQAYAEDLAQEEE
                     LIFICGHYEGYDERIKTLVTDEISLGDYVLTGGELAAMTMIDATVRLIPEVIGKESSH
                     QDDSFSSGLLEYPQYTRPYDYRGMVVPDVLMSGHHEKIRQWRLYESLKKTYERRPDLL
                     EHYQLTVEEEKMLAEIKENKE"
     gene            complement(2615..3133)
                     /gene="rimM"
                     /locus_tag="VQ540_001868"
     CDS             complement(2615..3133)
                     /gene="rimM"
                     /locus_tag="VQ540_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HET2545625.1"
                     /translation="MNYFNVGKIVNTQGLQGEMRVLSVTDFAEERFKKGAELALFDEK
                     DQFVQTVTIASHRKQKNFDIIKFKDMYHINTIEKYKRYSLKVAEEDLNDLDDGEFYYH
                     EIIGLEVYEGDSLVGTIKEILQPGANDVWVVKRKGKRDLLLPYIPPVVLNVDIPNKRV
                     DVEILEGLDDED"
     gene            complement(3164..3952)
                     /locus_tag="VQ540_001869"
     CDS             complement(3164..3952)
                     /locus_tag="VQ540_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000819180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HET2545626.1"
                     /translation="MKRFEVSTEIGSLSVTYQKQKKVLVCLNGAGLLPSYENFSLILE
                     KPPPTIGYLTIDFPNTGRSPIHDQAGKNLDNLADAVYEVLEELGISEYILCAHSWSGI
                     LACKLLEKPIKRQTLVAIEPTTKKVMFADFSENPYPEMEEQMRLIDECGPELYFKNLT
                     QATFSPETNKKIWELMQEKGLELENQDPEFQISGEITEEDFEDVSIEAHIPVFVFCQP
                     YREKEYRESEYWTSNTKLILGGNHHYLQWSESEKIAAIIRELSE"
     gene            complement(4529..4768)
                     /locus_tag="VQ540_001870"
     CDS             complement(4529..4768)
                     /locus_tag="VQ540_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HET2545627.1"
                     /translation="MDTIENLIIAIVKPLISQPDALTIKIEDTPEFLEYHLNLDQSDV
                     GRVIGRKGRTISAIRTIVYSVPTEYKKVRIVIDEK"
     gene            complement(4788..5060)
                     /gene="rpsP"
                     /locus_tag="VQ540_001871"
     CDS             complement(4788..5060)
                     /gene="rpsP"
                     /locus_tag="VQ540_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HET2545628.1"
                     /translation="MAVKIRLTRMGSKKKPFYRINVADSRSPRDGRFIETVGTYNPLV
                     AENQVTLKEDRVLAWLANGAQPSDTVRNILSKEGVLKKFHDSKFSK"
     gene            5230..5439
                     /locus_tag="VQ540_001872"
     CDS             5230..5439
                     /locus_tag="VQ540_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000953868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2545629.1"
                     /translation="MLSVNTILEKFYKEHQVKPFISPERELDTWLLSPKPVPKRNMDL
                     LVDDSLAGDIILLWRIQFGTFTTET"
     gene            5918..6139
                     /locus_tag="VQ540_001873"
     CDS             5918..6139
                     /locus_tag="VQ540_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2545630.1"
                     /translation="MSFYGLFYNGIAITPNTYLSAWFVNFIAALPLNFLIVEPIARFI
                     LSSFQKPFTGEEVEEVEDFQDDDEIPTII"
     gene            6222..7025
                     /locus_tag="VQ540_001874"
     CDS             6222..7025
                     /locus_tag="VQ540_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HET2545631.1"
                     /translation="MKKLATLLLLSTVALAGCSSVQRSLRGDDYVDSSLAAEESSKVA
                     AQSAKELNDALTNENANFPQLSKEVAEDEAEVILHTSQGDIRIKLFPKLAPLAVENFL
                     THAKEGYYNGITFHRVIDGFMVQTGDPKGDGTGGQSIWHDKDKTKDKGTGFKNEITPY
                     LYNIRGALAMANTGQPNTNGSQFFINQSSTDTSSKLPTSKYPQKIIEAYKEGGNPSLD
                     GKHPVFGQVIDGMDVVDKIAKAEKDEKDKPTTAITIDSIEVVKDYDFKS"
     gene            complement(7081..8622)
                     /locus_tag="VQ540_001875"
     CDS             complement(7081..8622)
                     /locus_tag="VQ540_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002918612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HET2545632.1"
                     /translation="MSILEVKNLSHGFGDRAIFEDVSFRLLKGEHIGLVGANGEGKST
                     FMSIVTGKMLPDEGKVEWSKYVTAGYLDQHSVLAERQSVRDVLRTAFDELFKAEARIN
                     DLYMEMAEDGADVDALMEEVGELQDRLESRDFYTLDAKIDEVARALGVMDFGMDTDVT
                     SLSGGQRTKVLLAKLLLEKPDILLLDEPTNYLDAEHIDWLKRYLQNYENAFVLISHDI
                     PFLNDVINIVYHVENQQLTRYSGDYYQFQEVYAMKKSQLEAAYERQQKEIADLKDFVA
                     RNKARVATRNMAMSRQKKLDKMDIIELQSEKPKPSFDFKPARTPGRFIFQAKNLQIGY
                     DLPLTKPLNLTFERNQKVAIIGANGIGKTTLLKSLLGIISPIAGEVERGDYLELGYFE
                     QEVEGGNRQTPLEAVWNAFPALNQAEVRAALARCGLTTKHIESQIQVLSGGEQAKVRF
                     CLLMNRENNVLVLDEPTNHLDVDAKDELKRALKEYRGSILMVCHEPDFYEGWIDQIWD
                     FNNLT"
     gene            complement(8624..9106)
                     /locus_tag="VQ540_001876"
     CDS             complement(8624..9106)
                     /locus_tag="VQ540_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000976721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HET2545633.1"
                     /translation="MMKKTYNHILVWGVIFYSICIVYFCFTPQEQSTVGVGTPDIQHL
                     GRLVFLLTPFNSLWKLGEVSDIGQLCWIFLQNILNVFLFFPLIFQLLYLFPNLRKTKK
                     VLLFSFLVSLGIECTQLILDFFFDFNRVFEIDDLWTNTLGGYLAWLLYKRLHKNKIRN
                     "
     gene            complement(9106..>9472)
                     /locus_tag="VQ540_001877"
     CDS             complement(9106..>9472)
                     /locus_tag="VQ540_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="50S rRNA methyltransferase"
                     /protein_id="HET2545634.1"
                     /translation="KLFAAIEYYIETTNRRVTFEYIMLNEVNDGVEQALELAELLKNI
                     KKSSYVNLIPYNPVSEHDQYSRSPKERVLAFYDTLKKKGGNCVVRQEHGTDIDAACGQ
                     LLFNTMKRDRQKAVAAVNP"
BASE COUNT         2796 a         2028 c         1698 g         2950 t
ORIGIN      
        1 attttcgaat caacaaaaaa attatccaac ttgactagtc acgaaaatcg gctgttacag
       61 tttttgttac cttgttttta aaaaatggtt gacatcgact cctatatgag tataatagtt
      121 atcatacatt agaaaagagg ttaactattt tgaaaaaagc tcacgtttat gctatccctg
      181 ctattggggc tgctctcatt gctgctttgg cacaaatcag tcttccaatt ggacctgttc
      241 ccttcactct gcaaaacttt gcaatcggct tgattgctac tgtctttaga ccgagagagg
      301 ctgtactttc tgctggactc tatcttcttc taggtgctat cggtcttcct gtctttgcag
      361 gaggtggagc tggttttcag gctttagttg gccctactgc aggctatctt tggttttatc
      421 tcgtttactc tggacttact tcctctctaa ccaacagcaa gagtggtgtt gttaagattt
      481 ttcttgcaaa cctcttgggt gatgcccttg tctttgtcgg cgggattctc agcttgcatt
      541 tcctagctgg aatggcattt gaaaaagctc ttgctgtggg ggttcttccc tttatcattc
      601 cagaccttgg caaacttctg gctattagtt ttattagccg tcccctactt caacgcctta
      661 aaaatcaggc ttactttact aactaaaaaa ggatatcgag ttatcatgac tcaatatcct
      721 tttcttttat tttgaaaact tatactcaat gaaaatcaaa gagcaaacta gaaagctagc
      781 cgcaggctgc tcaaaacact gttttgaggt tgtggatgaa actgacgaag tcagtaacca
      841 tacatacggc aaggcaaagc tgacgcggtt tgaagagatt ttcgaagagt attagttgcc
      901 tttaaaggca tccaccatcg tttgaaattc ttcatttgag agagtaatcc ctttgcccat
      961 tttagtatgg tctggactcc aagcacgaat atcaaacttt gcaggggcac cattaaagct
     1021 cacacggtta atttccttgg tccaaccttt ttcgttttca gaaagagtca acaagtgctc
     1081 ttcgatttca aatgtaaatt ctgccatttt cttctccttt tttagtttca ttagtttatt
     1141 cgtaaaatct tgtagatttt aggaaaattt tatataatat tgatataaaa gaagggaggc
     1201 caatatgaga cataaattcc agcaagttct aaataaaata catgattttt taaatggata
     1261 tgaccaacct gaccagactg aaaccaactc ccttacagcc actattgaag aggctatcca
     1321 gaaacaaacc gctgttcacc ttatcttgtc tgagacaagt tttacaggtg atatcatcaa
     1381 atatgatcag caaggccagc aaattatcgt gaaaaatttt gccaaaaatg tgagccggat
     1441 tatccgtata agcgatattc aacgcctgcg atttgtcccc tcaactgtcc aaacagccca
     1501 aaaaaataga tttaagaaag agtgagatgt agttgcttca tcccactctt ttttcttagc
     1561 gaatttgttc aaaatgtaaa tgaactgcaa tatgatctcc ataaccactt ctttccaagt
     1621 cacgttgtaa acgataggaa atgtagtgtt ctgcaatggt aatgtaacct gcgcccaata
     1681 aacgatgttc aaccatagat tgaatcatac tgatagtcgc acgttccacc ttggcttctt
     1741 gtaaatccaa aactaccttc ttagtgactt gagcaagatt ttgacgcaaa tcatctgtca
     1801 aaacataaac agtttgggct gccttcaaga tggcttggta aatcttatct ggattaaatt
     1861 cagcaatttc gccattacgt ttgattactt gcataggttt ctcctttatt ctttgttttc
     1921 tttgatttct gccagcattt tttcttcttc tactgtcagt tgataatgtt caagtaaatc
     1981 cggtctgcgc tcgtaggttt tctttaaact ctcgtacaat cgccactgac gaatcttttc
     2041 atggtggcca ctcatcaata catctggcac gaccatgcct cgataatcat agggacgtgt
     2101 gtactgagga tattctaaaa gacctgaaga aaaactatca tcttggtggc tagactcctt
     2161 gccaatcact tctggaatca ggcgaactgt agcatcaatc atggtcatag ctgccaattc
     2221 tccaccagtg aggacatagt cgcctaggga aatctcatct gttaccaagg tcttaatgcg
     2281 ctcatcataa ccctcatagt gcccacagat aaagattagc tcttcctctt gagccaaatc
     2341 ttcagcataa gcctgatcaa actgctttcc agcaggatcg aggagaataa cgcgcggatt
     2401 tttcttttca atagcatcaa aggaatcgaa aataggttgt gctctgagca acatgccctg
     2461 accgcctccg tagggctcat catctacatg acgggccttt tcagcatttt ctcgaaaatt
     2521 atgatactgg atatccaaga gccctttttc tcgagccttt ccaacgattg agtgctccag
     2581 tggagaaaac atctctggaa agagggttaa aatatcaatc ttcatcgtct aacccttcta
     2641 agatttccac atcgacccgt ttatttggaa tatcaacatt gagaaccact ggtgggatat
     2701 aaggtaaaag caaatcacgt ttgccttttc gtttgaccac ccagacatca ttagcacctg
     2761 gttgcaggat ttccttgatg gttccaacca agctatcacc ctcatagact tccaaaccga
     2821 taatctcgtg atagtaaaat tcaccatcgt ctaggtcatt caaatcttcc tcagcgacct
     2881 tgagactata tctcttgtac ttttcgatag tattgatatg gtacatatct ttgaatttaa
     2941 taatgtcaaa gttcttctgt ttacggtggc tagcgatggt cactgtttgg acaaactgat
     3001 ctttttcatc aaacaaagcc agctcagctc cttttttaaa ccgttcttct gcaaaatccg
     3061 tcacagacaa gactcgcatc tcaccctgta atccctgcgt attaacgatt ttcccaacat
     3121 taaagtagtt catcttgtct cctgtaatct ccttttttcc atcttattct gacaattctc
     3181 gaataatagc cgcaattttt tccgattctg accattgtaa ataatggtga ttccctccta
     3241 aaatgagttt agtattggaa gtccaatatt ctgattctct gtactctttt tctctataag
     3301 gctgacaaaa aacaaataca ggaatatgag cttctataga tacatcctca aaatcttcct
     3361 cagtaatctc tccagatatc tgaaattctg gatcttgatt ttccaactct aagccttttt
     3421 cttgcattaa ttcccagatt tttttattcg tttcaggact aaatgttgct tgagttaagt
     3481 tcttaaaata aagttcagga ccacactcgt caatcagcct catctgctct tccatttctg
     3541 gataaggatt ttctgaaaaa tcagcaaaca tgactttttt agttgtcggt tcaattgcta
     3601 ctaaagtctg acgcttaatt ggtttctcga gtaatttgca agctaaaatt ccactccaac
     3661 tatgtgcaca aagtatatat tcagaaattc ctaattcttc aagtacttca taaaccgcat
     3721 ctgcaagatt atctagattt tttccagctt ggtcatgaat cggactccta cctgtgttcg
     3781 gaaaatcaat tgtcaaataa ccaattgtag gaggaggttt ttcaagtata agtgaaaaat
     3841 tttcataact tggtagcaaa cctgctccgt ttagacaaac tagcactttc ttttgctttt
     3901 gataagtaac agagaggcta ccaatttctg tagatacttc aaacctcttc ataaagaaat
     3961 ccactcattc tatataatga attattaaaa atccttatct tttattttat cacgttccaa
     4021 ggattttctc aagttggagg aaggggacaa catctctact ttcccttcaa aaatccttcc
     4081 aaatcatgtt tatgttggta attaacggct gcggttttgt ctttctcaaa gacagtcttg
     4141 gtaaggtcaa tatgattaat agctacgatt gcgacggtgt agtaaatgat atcagccagt
     4201 tctctggcaa gttcctcgtt cgaatcctat cccttctttt cgaccagagc gcctattcaa
     4261 aacctcggct acttctccga cttcctccac taacttcata aagagacctt catcagtccg
     4321 agactgctgt taatgttcga ttaagtagtc ttggaattgc ctaaacgttc aatcttttat
     4381 agtatattga aactagaata gtacaccttt acttctaaaa cattgttaga aatcgatttg
     4441 actgtcctga tcgatttgtc ctgttcttgt ttcattttac tatatcttct attccacaca
     4501 aaaaagcgag acatccgtcc cgcccttctt atttttcgtc aataacgatt cttacttttt
     4561 tgtattcagt tgggacagag tagacaatcg ttcttatcgc agaaatagtg cgacccttac
     4621 gaccgattac acgacccaca tcgctttgat caagattcaa atgatattcc aaaaattctg
     4681 gtgtatcctc aatcttgata gttaaggcat ctggttgtga aattaagggt ttcacaatcg
     4741 caataatgag attttcaatc gtatccatct gtcaacctac tttaaactta ttttgaaaat
     4801 ttagaatcgt ggaatttttt caatacgcct tcttttgaaa ggatgttacg tactgtgtct
     4861 gaaggttgag ctccattagc caaccatgca agaacgcggt cttctttcaa agttacttgg
     4921 ttttcagcaa caagtgggtt gtaagttcca actgtttcga tgaaacgtcc gtcacgtggt
     4981 gaacgtgaat ctgctacgtt gatacggtag aaaggttttt tcttagaacc catacgagtc
     5041 aaacggattt taactgccat ttttaaagtc tcatttcttt aattttttat ttcggtgaaa
     5101 tagctgagct atttagcaca tgttctatta tagcagattt ctggcatgtg tcaagaaaaa
     5161 aacttgacag actataaatt tcttaaagta tttagaaatt tgttagaata ggaaataaat
     5221 gtttgaaaga tgctatccgt gaatactatt ttagaaaaat tttataaaga acaccaagtc
     5281 aaacccttca tatcgcctga acgagagttg gatacttggc ttctaagtcc caagcccgtt
     5341 cccaagcgaa atatggactt attagtagat gattcactag caggagatat cattttacta
     5401 tggagaatcc agtttggtac ttttaccact gaaacatgat tttaaaaact cccattcgaa
     5461 tatgattcaa aattcgctta gaatcaatgt tttcccgctt tttcaaaaaa taaattttca
     5521 tctaatttaa ataactttca attaagtgtg aattttgctt aaaatcatta aaaagcaccc
     5581 catggtgtga accatgaagt gttgtaaatg ctgtgttgta gctagttctt agcgtttaga
     5641 gaactggcta gctttacgag ctttcttaag atctggtttc caaaatactt tgagtacact
     5701 tatggtattg atgcccctaa acatctaaaa actctggtag aaaaagggta tgctcttgtc
     5761 gaaacttctt ttgactcact tgaccatcta aataatacca tgaaaaagaa tatcctgaag
     5821 aagaagggag ttactggact ttctaaaatg aaatcttgcg acctggatca agcccttcat
     5881 gagcattttt cagaagaaga attagctggt cactttcatg tccttctatg gactttttta
     5941 caatggcatt gctatcacac ccaataccta tctaagcgcc tggttcgtaa actttattgc
     6001 agctcttcct ctaaatttcc taattgttga accaattgcc cgttttatac taagttcttt
     6061 tcagaaacca tttactgggg aagaagttga agaagttgaa gattttcaag atgatgatga
     6121 aatcccaact attatctaag ccagttctgt aaactactaa tatttgaaat ccacttcttt
     6181 ttagggtaca atggtataaa tgaatttttg agaggatcag aatgaaaaaa ctagcaaccc
     6241 ttcttttact gtctactgta gccctagctg ggtgtagcag cgtccaacgc agtctgcgtg
     6301 gtgatgatta tgttgattcc agtcttgctg ctgaagaaag ttccaaagta gctgcccaat
     6361 ctgccaagga gttaaacgat gctttaacaa acgaaaacgc caatttccca caactatcta
     6421 aggaagttgc tgaagatgaa gccgaagtga ttctccacac aagccaaggt gatattcgca
     6481 ttaaactctt ccctaaactc gctcctctag cggttgaaaa tttcctcact cacgccaaag
     6541 aaggctacta taacggtatt accttccacc gtgtcatcga tggctttatg gtccaaactg
     6601 gagatccaaa aggggacggt acaggtggtc agtccatctg gcatgacaag gataagacta
     6661 aagacaaagg aactggtttc aagaacgaga ttactcctta tttgtataac atccgtggtg
     6721 ctcttgctat ggctaatact ggtcaaccaa acaccaatgg cagccagttc ttcatcaacc
     6781 aaagctctac agatacctct tctaaactcc ctacaagcaa gtatccacag aaaattatcg
     6841 aagcctacaa agaaggtgga aaccctagtc tagatggcaa acacccagtc tttggtcaag
     6901 tgattgacgg tatggatgtt gtggataaga ttgctaaggc cgaaaaagat gaaaaagaca
     6961 agccaactac tgctatcaca atcgacagca tcgaagtggt gaaagactac gattttaaat
     7021 cttaaaaacc aaaaaaatac agtatccaca ttcggtactg tatttctttt actctcattc
     7081 ttaagttaaa ttattaaaat cccatatttg gtctatccag ccttcataaa agtctggctc
     7141 gtggcagacc ataaggatag atcccctata ttctttgaga gcgcgtttga gctcatcctt
     7201 tgcatccaca tccaaatggt tggtcggctc gtccagcact aaaacgttgt tttcacgatt
     7261 catcaagaga cagaaacgaa ccttggcttg ctctccccct gataatactt gaatctggct
     7321 ttcaatatgt ttggttgtca aaccacaacg ggcaagggct gcacggactt ctgcttgatt
     7381 aagggcagga aaggcattcc agacagcttc aagaggagtt tggcgattac cgccttctac
     7441 ttcctgctca aaataaccaa gttctaaata atctccacgc tccacttccc cagcgattgg
     7501 cgagataatg cccaagagac tcttcaagag agttgttttt ccaataccat tagcaccaat
     7561 aatcgcaacc ttttgattgc gttcgaaggt aagatttaaa ggcttagtaa gaggaaggtc
     7621 gtaaccaatt tgcaagttct tggcttggaa gataaagcgc cctggtgtac gagctggttt
     7681 gaaatcaaag gatggttttg gtttctcact ttggagttcg ataatatcca tcttatccaa
     7741 tttcttttga cgagacatag ccatattacg agttgcaaca cgggctttat tacgagccac
     7801 aaagtccttg aggtctgcaa tctctttctg ctggcgttcg taggctgcct ctagctgaga
     7861 tttcttcata gcataaactt cttggaactg gtagtagtca ccagagtaac gcgtcagctg
     7921 ttgattttcc acatgataga caatattgat aacgtcattg aggaatggaa tatcgtgcga
     7981 aatgagaaca aaggcattct catagttttg gagatagcgc ttgagccaat caatatgctc
     8041 agcatccaag tagttggtcg gctcgtccaa cagcaagata tcaggctttt caaggagaag
     8101 ttttgccaaa agcaccttgg ttctttgccc acctgacaaa gaagttacat ccgtatccat
     8161 gccaaagtcc ataacaccaa gagcacgcgc tacttcgtca atcttagcat ccaaggtata
     8221 gaaatcacga ctctccagac ggtcttgaag ttctcctact tcttccatga gagcatcaac
     8281 atccgcaccg tcttcagcca tttccatata gaggtcattg atacgagctt cagctttgaa
     8341 aagctcatca aaagccgtac ggagaacatc acgcaccgac tgtctttcag caaggacaga
     8401 gtgctgatcc aagtaaccag ccgtcacata tttggaccac tcaacctttc cttcatctgg
     8461 cagcatttta ccagtcacga tactcataaa ggttgatttt ccttcaccat tggcaccgac
     8521 caggccgata tgttctccct tgaggagacg gaaggacaca tcttcaaaaa ttgcacggtc
     8581 accaaaaccg tgactcagat ttttaacttc taaaatactc attttaattc cttatcttgt
     8641 ttttatgtaa tcgtttataa aggagccaag ccagatagcc acccaaagtg ttggtccaca
     8701 aatcatcaat ctcaaagacg cgattgaaat caaagaaaaa gtccaagatt aattgcgtac
     8761 actcgattcc aagactcaca agaaaactaa aaagaaggac cttttttgtt ttccgcaaat
     8821 ttggaaatag ataaaggagt tggaaaatca gaggaaaaaa caagaagaca ttgaggatat
     8881 tttgtaaaaa aatccaacat aattgtccaa tgtcactcac ttcgcccagt ttccagagag
     8941 aattgaaagg agtcaaaaga aaaaccaggc gtccaagatg ctgaatatct ggagttccca
     9001 ctcccacggt agattgttct tgaggagtaa agcaaaaata gacaatgcaa atgctataga
     9061 aaatgactcc ccagaccaaa atatgattat aagtcttctt catcattaag gatttaccgc
     9121 tgcgactgcc ttctggcggt cacgtttcat tgtgttaaag agcaattgtc cacaagctgc
     9181 gtcaatatct gtaccatgct cttgacgaac cacacagttg cccccttttt tcttaagcgt
     9241 atcatagaaa gccaacacgc gctctttggg actacggcta tattggtcat gctcactaac
     9301 tgggttataa ggaatcaagt ttacataaga cgatttcttg atgttcttga gcaattcagc
     9361 caattccaag gcttgttcca caccgtcgtt gacttcatta agcatgatat attcaaaggt
     9421 tacacgacgg tttgttgtct caatgtagta ttcaatagca gcaaagagtt tt
//
LOCUS       DAVBDR010000070         8942 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.070, whole genome shotgun sequence.
ACCESSION   DAVBDR010000070 DAVBDR010000000
VERSION     DAVBDR010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8942)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8942)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8942
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.070"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            complement(135..1103)
                     /locus_tag="VQ540_001878"
     CDS             complement(135..1103)
                     /locus_tag="VQ540_001878"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HET2545635.1"
                     /translation="MSFSDLKLFALSSNKELAERVAQEIGIELGKSSVRQFSDGEIQV
                     NIEESIRGKHVFILQSTSSPVNDNLLEILIMVDALKRASAESVNVVMPYYGYARQDRK
                     ARAREPITSKLVANMLEVAGVDRLLTIDLHAAQIQGFFDIPVDHLMGAPLIADYFERR
                     GMVGSDYVVVSPDHGGVTRARKLAEFLKTSIAIIDKRRSVDKMNTSEVMNIIGKVEGK
                     TCILIDDMIDTAGTICHAADALAEAGAVEVYASCTHPVLSGPATDNIQKSAIKKLVVL
                     DTIYLPEERLIDKIEQISIAHLLGDAIVRIHEKRPLSPLFDIEKKI"
     gene            complement(1248..2063)
                     /locus_tag="VQ540_001879"
     CDS             complement(1248..2063)
                     /locus_tag="VQ540_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family intramembrane metalloprotease"
                     /protein_id="HET2545636.1"
                     /translation="MKKSSILFIFILLLCIGLQYETIYYTDGSRSGAEYGLMGVSIFL
                     ALFYMIPALYFLFRIGKKWELPKKVLILSLLGGMFLSGWLSSFTNTYIHDLLGVLFPD
                     SPFLNAFESAIVAPLVEEPLKLLPLVFVLALIPVRKLKSLFLLGIASGLGFQMIEDIG
                     YIRTDLPEGFDFTISRILERIISGIASHWTFSGLAVVGVYLLYRAHKEQKVGKKQGLI
                     FLGLALRTHFLFNSPFVELETELPLAIPVVTAIALYGFYHAYCFVEKHNELMT"
     gene            complement(2088..2585)
                     /locus_tag="VQ540_001880"
     CDS             complement(2088..2585)
                     /locus_tag="VQ540_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase"
                     /protein_id="HET2545637.1"
                     /translation="MSYFEQFMQANQAYVALHGQLNLPLKPKTRVAIVTCMDSRLHVA
                     QALGLALGDAHILRNAGGRVTEDMIRSLVISQQQMGTREIVVLHHTDCGAQTFENEPF
                     QEYLKEELGVDVSDQDFLPFQDIEESVREDMQLLIESPLIPDDVIISGAIYNVDTGSM
                     TVVEL"
     gene            complement(2658..4019)
                     /gene="radA"
                     /locus_tag="VQ540_001881"
     CDS             complement(2658..4019)
                     /gene="radA"
                     /locus_tag="VQ540_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000336571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HET2545638.1"
                     /translation="MAKKKATFVCQNCGYNSPKYLGRCPNCGSWSSFVEEVEVAEVKN
                     ARVSLTGEKTKPMKLAEVTSINVNRTKTEMEEFNRVLGGGVVPGSLVLIGGDPGIGKS
                     TLLLQVSTQLSQVGTVLYVSGEESAQQIKLRAERLGDIDSEFYLYAETNMQSVRAEVE
                     RIQPDFLIIDSIQTIMSPEISGVQGSVSQVREVTAELMQLAKTNNIAIFIVGHVTKEG
                     TLAGPRMLEHMVDTVLYFEGERHHTFRILRAVKNRFGSTNEIGIFEMQSGGLVEVLNP
                     SQVFLEERLDGATGSSIVVTMEGTRPILAEVQALVTPTMFGNAKRTTTGLDFNRASLI
                     MSVLEKRAGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKDKPTNPQECFVGE
                     LGLTGEIRRVNRIEQRINEAAKLGFTKIYVPKNSLTGITLPKEIQVIGVTTIQEVLKK
                     VFA"
     gene            complement(4033..4548)
                     /locus_tag="VQ540_001882"
     CDS             complement(4033..4548)
                     /locus_tag="VQ540_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HET2545639.1"
                     /translation="MKIIFVRHGEPDYRELEERSYIGFGIDLAPLSEMGRQQVQKLSK
                     NPLLSSAEIIVSSAVTRALETASYVVCATGFPLRVEPLLHEWQVYKTGIENFETARRL
                     FLENKGELLPNSPIQYETATEMKSRFLECMSKYREHQTVVVVAHRMLMRQFVPNEKID
                     FCQVIECELEI"
     gene            complement(4550..4993)
                     /locus_tag="VQ540_001883"
     CDS             complement(4550..4993)
                     /locus_tag="VQ540_001883"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HET2545640.1"
                     /translation="MKIRGFELVSSFTDENLLPKRETAHAAGYDLKVAVRTVVAPGEI
                     VLVPTGVKAYMQPTEVLYLYDRSSNPRKKGLVLINSVGVIDGDYYGNPGNEGHIFAQM
                     KNITDQEVVLEVGERIVQAVFATFLIADGDAADGVRTGGFGSTGH"
     gene            complement(5050..5147)
                     /gene="ffs"
                     /locus_tag="VQ540_001884"
     ncRNA           complement(5050..5147)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="VQ540_001884"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            complement(5180..5647)
                     /locus_tag="VQ540_001885"
     CDS             complement(5180..5647)
                     /locus_tag="VQ540_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deaminase"
                     /protein_id="HET2545641.1"
                     /translation="MYYTLEEKEVFMREALREAEIALEHDEIPIGCVIVKDGEIIGRG
                     HNAREELQRAVMHAEIMAIEDANLSEESWRLLDCTLFVTIEPCVMCSGAIGLARIPNV
                     VYGAKNQKFGAAGSLYDILTDERLNHRVEVEIGILEDECAAIMQDFFRNRRKK"
     gene            complement(5848..7134)
                     /locus_tag="VQ540_001886"
     CDS             complement(5848..7134)
                     /locus_tag="VQ540_001886"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HET2545642.1"
                     /translation="MTSVVVVGTQWGDEGKGKITDFLSANAEVIARYQGGDNAGHTIV
                     IDGKKFKLHLIPSGIFFPEKISVIGNGMVVNPKSLVKELSYLHEEGVTTDNLRISDRA
                     HVILPYHIELDRLQEEAKGDNKIGTTIKGIGPAYMDKAARVGIRIADLLDKDIFRERL
                     ERNLAEKNRLFEKLYDSKAIVFDDIFEEYYEYGQQIKKYVIDTSVILNDALDNGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGIGPSKIDKVVGVCKAYTSRVGDGP
                     FPTELFDEVGERIREVGHEYGTTTGRPRRVGWFDSVVMRHSRRVSGITNLSLNSIDVL
                     SGLDTVKICVAYDLDGQRIDYYPASLEQLKRCKPIYEELPGWSEDITGARNLEDLPEN
                     ARNYVRRVSELVGVRISTFSVGPGREQTNILESVWS"
     gene            complement(7365..7601)
                     /locus_tag="VQ540_001887"
     CDS             complement(7365..7601)
                     /locus_tag="VQ540_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecX"
                     /protein_id="HET2545643.1"
                     /translation="MLQKIYEQMTNFYDSIEEEYGPTFGDNFDWEHVHFKFLIYYLVR
                     YGIGCRRDFIVYHYRVAYRLYLEKLVMNRGFISC"
     gene            7867..8664
                     /locus_tag="VQ540_001888"
                     /pseudo
     CDS             7867..8664
                     /locus_tag="VQ540_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436304.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(8699..>8942)
                     /locus_tag="VQ540_001889"
     CDS             complement(8699..>8942)
                     /locus_tag="VQ540_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2545644.1"
                     /translation="LLPTLTTPSVIIMDNARFHRMGKLELLCEEFGHKLLPLPPYSPE
                     YNPIEKTWAYIKKNLKKVLPSCNTFYEALFSCSCFN"
BASE COUNT         2867 a         2124 c         1442 g         2509 t
ORIGIN      
        1 tgatgacgta cagtcatatt tcttctcttt ttattatatc acagttttaa atctagcttt
       61 actagattca ccgctactat ctatttattc ggaaaaaaga cgaaaaaacc tgagaatcat
      121 ctcaggcttg gtcattaaat ttttttctca atatcgaaaa gtggagaaag tggtcgtttt
      181 tcatgaatac gtacgatagc atcccctagg agatgagcga ttgaaatctg ctcaatctta
      241 tcaatcaaac gctcttctgg cagatagatg gtatccaaaa caaccaattt cttaatagct
      301 gatttttgga tattgtccgt agcaggacca gaaagaactg ggtgcgtaca gcttgcatag
      361 acttcaacag caccagcttc cgcaagagca tctgccgcat gacaaatcgt tccagcggta
      421 tcaatcatat catcaatcaa gatacaagtc ttgccttcaa ccttaccgat gatgttcata
      481 acttcactag tattcatctt atcaacgcta cgacgtttat caataatagc gatagatgtt
      541 ttcaaaaatt ctgccaactt acgagcacga gtcacccctc catggtccgg gctgacaacc
      601 acatagtcag aaccaaccat accacgacgc tcaaaataat ctgcaatcag aggagcaccc
      661 atcaaatgat ccacaggaat atcaaagaat ccttgaattt gcgcagcatg caagtcgatg
      721 gtcaataaac gatccactcc agctacttca agcatatttg cgacaagttt tgaagtgatt
      781 ggctcacgcg ctctcgcctt tctatcctga cgtgcatacc catagtaagg catgacaaca
      841 ttgacagatt ctgcactcgc acgcttcaaa gcatctacca taatcaaaat ttcaagcaga
      901 ttgtcattta caggcgaact agttgattgt aggataaaga cgtgtttccc acggattgat
      961 tcttcaatgt tgacctgaat ctctccatct gaaaattggc gaacacttga tttccccaac
     1021 tctatcccaa tctcctgcgc cacacgttct gccaattctt tattagaaga aagggcaaac
     1081 agctttaaat cagaaaaaga catgatttcc tccggtatat atgtatcgct tgtgcttttc
     1141 acaagatttt ccatctacca ttgtagcgct ttttgcacta tttttcaatc aaaaataaaa
     1201 gaagggcacc atatttgtac ccttgcatca ttcttttgaa aaatattcta ggtcatcaac
     1261 tcattgtgtt tctcaacaaa gcaataagca tgataaaaac catagagagc aatagccgta
     1321 accactggaa tcgctaaagg caactctgtt tccaactcca caaaaggaga gttaaacaag
     1381 aagtgagttc tcaaggctaa acctagaaaa ataaggccct gtttcttgcc aaccttctgt
     1441 tctttatggg ctctgtaaag caagtaaaca cctactacag ctagacctga aaaagtccag
     1501 tgagaggcaa ttcctgagat gatacgctct aaaattcgcg aaatagtaaa gtcaaagccc
     1561 tctggcaaat ccgtacgaat ataaccaata tcctcaatca tttggaatcc caaaccggaa
     1621 gcaattccaa gtaaaaacaa agattttaat tttcgcacag gaatcaaagc caaaacaaaa
     1681 acaagtggca ataatttcaa gggttcttct accaaaggag ccacaatagc actttcaaag
     1741 gcatttaaaa atggactatc tgggaaaaga acccccagta aatcatggat ataagtatta
     1801 gtaaaactag acaaccagcc tgaaaggaac atccctccca ataaagacag aatcaaaacc
     1861 ttctttggca attcccattt tttcccaata cggaagagaa aataaagagc cggaatcatg
     1921 taaaagagag ctagaaagat agaaactccc attagtccat attccgcacc tgacctcgaa
     1981 ccgtccgtat agtagatggt ttcatactgt aaaccaatac atagcaataa aataaaaata
     2041 aataaaatac tgcttttctt catacacttt ctttctaaat gaagtattta taattctacg
     2101 actgtcatac ttcctgtatc aacattgtaa atggcaccag agataatgac atcgtctggt
     2161 attaggggag actcgataag cagttgcata tcctcgcgta cactctcttc tatatcttgg
     2221 aagggcaaga agtcctggtc tgacacatct acacctaatt cctcttttaa atactcctga
     2281 aaaggttcat tttcaaaggt ctgagcacca cagtctgtat ggtgcaatac cacaatctct
     2341 cttgtcccca tttgttgctg ggaaataact agcgaacgaa tcatgtcttc agtcactcga
     2401 ccacctgcat tccgcaagat atgagcatcc ccaagtgcca agcccagagc ttgcgcaacg
     2461 tgcagacgag agtccataca ggtcacaata gctactcttg ttttgggttt aagtggcaga
     2521 tttaactgcc catgtagggc aacataagcc tgattagctt gcataaactg ttcaaaatac
     2581 gacacgattc cctccttgaa aatttgatag tcaaatattt ctcctatctt atcattttta
     2641 agagaatttg tcacggatta tgcaaagacc tttttcaaaa cttcctgaat cgttgtcacg
     2701 ccaatgacct gaatttcctt aggcagagtg attcctgtca aggaattctt aggtacataa
     2761 atcttagtaa agcccagttt agcagcttcg ttgatgcgtt gctcaatacg attcacgcgc
     2821 cgaatctctc ctgtcaagcc cagttctccg acaaaacatt cctgaggatt agttggcttg
     2881 tctttgtagc tcgaagcaat agcaactgca acagccaagt caatggcagg ttcatccaat
     2941 ttaacaccac cagcagattt gagataggca tcctgatttt gcaagagaag ccctgcccgt
     3001 ttttccaaaa cagacataat caagctagca cggttaaaat caagtcctgt cgtagtacgc
     3061 ttggcatttc caaacatggt cggtgttacc aaagcctgaa cctccgccaa aatcggacgc
     3121 gtcccttcca tggttacaac gatggaggaa ccagtcgccc catccaaacg ctcttctagg
     3181 aaaacttgac tcggattgag tacctcaacc aagccgcccg actgcatctc aaaaatccca
     3241 atctcattag tggaaccaaa acgatttttg accgctctca aaatacgaaa ggtgtggtga
     3301 cgctcccctt caaagtaaag caccgtatcc accatatgct ccaacatacg aggcccagcc
     3361 aaggttcctt ctttggtcac atgacctacg ataaagatgg caatgttatt ggtcttggcc
     3421 aactgcatga gttcagcggt cacttcacgc acctgagaaa cagacccctg cacccctgaa
     3481 atctcaggag acatgatggt ctggatggaa tcaataatga gaaagtctgg ctggatacgc
     3541 tccacttctg cacgaacact ctgcatattg gtctctgcat agagataaaa ctcactatca
     3601 atatcaccta agcgctctgc acgtagttta atctgctggg cagactcctc cccactgaca
     3661 tagagaactg tccccacttg ggacaactgg gttgagactt gtaggagaag agttgatttc
     3721 ccaatcccag gatccccacc gatgaggacg agacttcctg gtaccactcc gcctccaagc
     3781 acacggttga attcctccat ctccgtcttg gttcgattga cattgatgga agtcacctca
     3841 gctagtttca tgggcttggt tttctcacct gtcaaggaca cacgcgcatt cttgacctcg
     3901 gcaacctcaa cctcttccac aaaagaagac caagacccac agttggggca acgtcccaga
     3961 tatttagggg aattataccc acaattttga catacaaatg tcgctttttt ctttgcgatg
     4021 acaaacctct ttctatatct ctaactcaca ctcaatcact tggcaaaaat caatcttctc
     4081 atttggcaca aactggcgca tgagcattcg atgagcaaca actaccacag tctgatgttc
     4141 tcgatactta gacatacatt ctagaaaccg agacttcatt tccgtagctg tctcatattg
     4201 aataggacta ttaggaagca actccccctt gttttctaaa aacagtcttc tagctgtttc
     4261 aaagttttct attcctgttt tatagacctg ccattcatgt aataaaggct ctactcttaa
     4321 aggaaaaccc gtagcacata ccacatacga agccgtttct aaagctcttg tgactgcaga
     4381 agatacgatt atttcagctg acgagagtaa aggatttttg ctcaatttct ggacttgctg
     4441 ccgtcccatc tcagacaagg gtgccaaatc tatcccaaat cctatataag aacgctcctc
     4501 taactcacgg taatctggct ccccatgacg tacaaagata atcttcattc tagtgccctg
     4561 tcgatccaaa tccaccagtt cgaacgccat cagccgcatc tccatctgca attaagaaag
     4621 tagcaaaaac agcctggaca atacgctccc caacttcaag aacaacctct tggtctgtga
     4681 tattcttcat ctgcgcaaaa atatgccctt catttccagg atttccataa taatccccat
     4741 caatgactcc aactgagtta attaaaacca agcccttctt acgaggattt gaagaacgat
     4801 catagaggta gagaacctca gtcggctgca tataagcctt aacccctgtc ggaaccaaga
     4861 caatctctcc tggcgcaaca actgtacgca cagcaacctt taagtcgtaa ccagccgcat
     4921 gcgctgtctc acgcttgggc aataaatttt catctgtaaa actcgaaacc aattcaaaac
     4981 cacgaatttt cataattttc tcttttctat tatcatttat tctagattat tctatcttat
     5041 ttattcggaa aaagcacgaa aaaaagagca cacaattcaa atcgcttagg gctgctggat
     5101 tcctcccctg acccgcttca cgcagaactg ttgctccact atttattata tcacattcct
     5161 attcatttta aaagcaaaat tattttttcc gtctatttct aaaaaaatcc tgcatgatag
     5221 ctgcgcattc atcttccaaa attcctattt caacctccac acgatgatta agacgctcat
     5281 ctgtcaagat atcgtacaaa cttccagcag cgccaaattt ctggttttta gccccataga
     5341 ccacatttgg aatgcgggca agcccaatcg ccccactaca catgacacaa ggttcaatgg
     5401 tcacaaaaag tgtgcaatcc agcaagcgcc agctctcctc actcaagttc gcatcctcta
     5461 tagccataat ttccgcatgc ataaccgctc gctgtaattc ctcacgcgca ttatgcccac
     5521 gaccaatgat ttccccatct ttgacaatca cacaaccaat tggaatttca tcgtgttcaa
     5581 gagcaatctc agcctctctc aaagcctccc tcataaagac ttctttttct tcaagcgtat
     5641 aatacatctc ttttctcttt tcctacttat cgattttatt attatatcat gaatcccaac
     5701 acaaaaaaag ccaccgaatg cggtgactct atagggagat tattatgaaa aagaaaagtt
     5761 taggatattt gttacaacaa gttaggaggt cttcttgtaa ctgtctatag tatacccgac
     5821 ctatcttaaa caaatcttaa aaatctctta ggaccaaaca ctttctaaaa tatttgtttg
     5881 ttcacgacca ggacctactg agaaagtaga aatacgaacg ccaaccaatt cactcacacg
     5941 acgaacatag ttacgcgcat tctcaggaag atcttccaaa ttgcgagctc cggtaatatc
     6001 ttctgaccaa cctggcaact cttcatagat aggcttgcaa cgtttcaatt gctcaagact
     6061 agctggatag tagtcaatac gttgaccgtc aagatcatag gccacacaaa ttttcacagt
     6121 atccaagccg ctcaaaacat caatagagtt caaagaaagg ttagtaatac cagaaacacg
     6181 acggctatga cgcatcacaa ctgagtcaaa ccaacctaca cgacgtggac gaccagttgt
     6241 tgtaccatat tcatgaccca cttcacggat acgttctccc acttcatcaa acaactcagt
     6301 tgggaaagga ccatctccta cacgactcgt ataagcttta catacaccta caaccttgtc
     6361 aatcttgctt ggaccgatac cagaaccaat tgtcacacca ccagctacag ggtttgatga
     6421 cgtaacaaat ggataagtac cttgatcgat atctagcata acaccttgtg caccttcaaa
     6481 aagcacacgt ttgccattat caagcgcatc attcaagata acagatgtat ctatcacgta
     6541 tttcttgatt tgttgaccat attcgtaata ttcttcaaaa atatcatcga aaacaatcgc
     6601 tttactgtca tacaattttt caaaaagacg attcttttca gcaaggttac gttctaaacg
     6661 ctcacggaaa atatctttat ctaaaagatc tgcaatacga attccaacac gagcagcctt
     6721 gtccatataa gctggaccaa ttcccttaat tgtcgtacca atcttattgt cgcccttagc
     6781 ttcttcttgc aagcgatcca actcgatatg ataaggcaaa ataacatgcg cacgatcaga
     6841 aatacgcaag ttatcagttg ttacaccttc ctcatgaaga tagctcaact cttttacaag
     6901 agatttagga tttacaacca taccattccc aatgacagat attttttcag ggaagaaaat
     6961 cccagatgga atcaagtgca acttaaattt cttaccgtca atcacaatcg tgtgaccagc
     7021 attatcacca ccttggtaac gtgcaattac ttctgcattc gctgaaagga agtctgtaat
     7081 cttcccttta ccttcatcac cccattgggt acctacaaca acaactgaag tcataatttt
     7141 gtctgagccc tcaggctctt cctttctcac atacatggca ggactctcac ctgcaattat
     7201 atcttacaat ttattataat aaaaaatcgc ctttttatca agaagaaaca atagaaagat
     7261 ttgctatttc caactattaa aaaatgattt agaaaaatta ctagctattt actattatct
     7321 ttccataaaa gagtaaatta gttcggaaat ttactaaaat tacctcaaca agaaataaaa
     7381 ccccgattca ttaccaattt ttcaagatac aaacgataag caacacgata atggtaaacg
     7441 ataaaatccc tacgacaacc aatgccatat ctcactaaat aataaattaa aaatttaaaa
     7501 tgaacatgtt cccagtcaaa attatcacca aatgtaggac catactcttc ttcaatacta
     7561 tcatagaaat tagtcatctg ctcataaatt ttttgtaaca taatcaaata ctccttttct
     7621 tttttataaa cttattctaa caaaaaattt tacacattca ctatcaattc ctgaattgtt
     7681 aaaataccag cctcaacaag ataaaaatag gaaaagttga caaaatagaa acaaatttgc
     7741 tacctaaatt tcaaacgatt aaagttctaa aaagaccgcc ttaaaacttt tgggtaaatc
     7801 ctattagaac tataatattt atatatatgt attatggttc tgattttcta gtataaaaaa
     7861 attcaaacta gaattcttct tagaaaaggc cgttttaagt gctatcattg ctcaaaaatg
     7921 gaggtcgctg agacttctat cgtcaagaag aatcatcaaa ttccttgtat catcaaccaa
     7981 aagattgctc agaagttaat tgaaaagact tctatgaccg acattgatca tcagttgtct
     8041 atttcaactt caactgtcat tcgcaagatc aataattttc actttgagca tgatttttcg
     8101 cgtcttcctg agattatgtc ctaggacgtt gaaacagtcc ggggagtgac tgtttcaatc
     8161 gggagatgga gatgagcttt attgctcagg actttgataa actcaatatc ataactgttc
     8221 ttgagagcag aacacaagcc atcatccgaa atcccatgaa tacaaggcta tcaagcgcta
     8281 ctggaagctc attcaacaag atagtcagaa actgagtgat aaacgatttt atcgccctac
     8341 ttttcgtatg cacttgacta ataaagaaat tctagataaa cttttgagct attccgaaga
     8401 cttgaaacac cactataatc tctatcagct cttgcttttc cacctctgtt tcagactttg
     8461 tttaaaacct tcctcaaaga taaagagaaa atcgtcaacg cccttcaatt accttattcc
     8521 aacgccaaac tggaagccac caataatctc atcaaactta tcaagcacaa tgcctttggt
     8581 tttaggaact ttgaaaactt caaaaaagaa aggacgaaat ttgtcctttc tagatcttcg
     8641 ctttcttcaa cccactacag ttgacaaaga accgaaaaat gtctcgcctc taatatagtc
     8701 aattgaaaca agaacaagag aaaagagcct cgtaaaaggt attgcaactt ggtaatacct
     8761 ttttgaggtt ctttttgata taagcccatg ttttctcaat aggattgtac tcaggtgagt
     8821 agggaggaag aggtaaaagt ttatgcccaa actcctcgca taaaagttct aacttaccca
     8881 ttctatggaa tcttgcatta tccataataa taaccgatgg tgtggttaat gttggtaaga
     8941 ga
//
LOCUS       DAVBDR010000071         8830 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.071, whole genome shotgun sequence.
ACCESSION   DAVBDR010000071 DAVBDR010000000
VERSION     DAVBDR010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8830)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8830)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8830
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.071"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            264..1322
                     /locus_tag="VQ540_001890"
     CDS             264..1322
                     /locus_tag="VQ540_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2545645.1"
                     /translation="MKDDQKYLLAGLYSLLVAIFYFPLIESKGIFVSILMAVLLLYLI
                     YFIATVIHIVIIKFIRKKSFKYLVLYPFTYDGSWRFQPINLLYFPEMVRDVIPINLVQ
                     EYCQGQPYGLLKKMLKRIRLSREIALLLATIIVYFFTHRILPLSVFTFIFSYILLFAQ
                     SYLGGNTVWIGNRRLIIDDEFEKILLSKSYIKEISSARYSEYLTCEYKNLTPIILLAI
                     FENLLDSYLLQNQSEVDLDIFYKVLPLLYKEKYTMGFNYFVSLNYLLYKVGFLGIIYD
                     NEALGDLSKQYLNRNISELQDGSFDGGIQDAVASKQIVVINEFIACLNSRCMPSQYDR
                     FFYKDRPYIFSRKSPIKG"
     gene            1637..2611
                     /locus_tag="VQ540_001891"
     CDS             1637..2611
                     /locus_tag="VQ540_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2545646.1"
                     /translation="MKNKRYFFDTILMILLLISTIFCVSPVFIKLDILGTPSHAILTF
                     VLAIPLFYILSQCLHTLLLLVSSIFCKLRPIYFYFIFVIIIGARKYYRILFHQLMGFS
                     PGIAVFYKESQTTKNLFKFYYFLYFTTLISYYFFFTFVYDKPLLLPLIPFSIIIALVQ
                     KLYRIENQQLFLLKSKVLTILESKKNCEFNLQDYHEIWKLQSKSELPCVALSYISLIK
                     PYLSESVREQIDLLEVKRFKKINHPISLYGMLDVIKLNLYLRHYNEKNKYESMLKKIL
                     EVRPDFVLIEQNIDDSLNSSQPLSLSLAISEIQLLLEVYMGIKHVSTK"
     gene            2991..3365
                     /locus_tag="VQ540_001892"
     CDS             2991..3365
                     /locus_tag="VQ540_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPH_0224 family bacteriocin-like peptide"
                     /protein_id="HET2545647.1"
                     /translation="MELVLPNNYVVLEQEEMMYLDGGFSIPRWPVATAINIAFNGVLG
                     GGAISLVRNYIRNYGLRRVTSAIAGAAARYVGVRVANRVAGFALSAINGFAAWMSIGD
                     AITTIWANNDVNRRDPNLNALW"
     gene            3573..4475
                     /locus_tag="VQ540_001893"
     CDS             3573..4475
                     /locus_tag="VQ540_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2545648.1"
                     /translation="MIRKLIVFLLMLPLFVLWLELHVLVNNLLLNLESPLDFVISMSL
                     AFCSLILSKIVLDILYALKDLYKKEGLIKIFPFIFIRRKKVNVRFSPYFSFHRKSLSP
                     DDLRSRIIWSFILEIAIILVFILKIPFAIIMLTTIFFWTIMDINHLVFNKTEFLFNQN
                     KWQKEDSFESNLHKILMDKIQKSELSYSDLMSLLLYDAMNQSTFLTDSELFEDILKKI
                     EDSHNTLLCTGLVELLLYEISISNNNNWQEKVDKIRIQLIRINQLDFFYYTSWLRQNF
                     DFCMNREYHKMKSRKLLLSNKKIV"
     gene            4531..4770
                     /locus_tag="VQ540_001894"
     CDS             4531..4770
                     /locus_tag="VQ540_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HET2545649.1"
                     /translation="MELVLPNNYVVIDEEVMMYLDGGAYLSKRACQGICAAAGVLATA
                     AGKIAYCIGYGVLNRGCDINENPYPWDGFISATVR"
     gene            4767..5495
                     /locus_tag="VQ540_001895"
     CDS             4767..5495
                     /locus_tag="VQ540_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2545650.1"
                     /translation="MSNVDKIRKIHIIVCWVYIFLSFRAIINDTEYFLLIFLAFIYSI
                     VSLPLYSVKNKIVSICLVINSILLMSFPILINKFFPESFLTYTVLISVFILELAIFHL
                     IRKDFDIKLTNEYKKISQFRSKVSQSPWIKYLEISSFILTIFPSILYGKVDNHVLTLI
                     FLIKICVDTTIKFLFIRLFDTSTLMKRRIFFLFALDVIAYLFLGYLLVIQKAGYLFSV
                     LLLFSNFSVPFIKEKEYELFKNSK"
     gene            6630..6869
                     /locus_tag="VQ540_001896"
     CDS             6630..6869
                     /locus_tag="VQ540_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2545651.1"
                     /translation="MKLLDCILDYQERFNGKTCQVSTNYKYLEIFKVNFCLTDLHHLF
                     DLYKITRDYASQTKPAIQDGVFILEDFRNILCTMM"
     gene            7419..>8830
                     /locus_tag="VQ540_001897"
     CDS             7419..>8830
                     /locus_tag="VQ540_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein"
                     /protein_id="HET2545652.1"
                     /translation="MNKKKMILTSLASVAILGAGFVTSQPTFVRAEEAPVASQSKAEK
                     DYDAAVKKYEAAKKEYEDGKAAQKKYEDDQKKTEEKAEEERKASEEEQAANLKYQQEL
                     VKYIRENDPTKKAEAKKAMDEAEKEYKKKQTEFAEVRAKVIPSAEELKKTRQKAEEAK
                     AKEAELTKKVEEAEKKVTEAKQKVDAEHAEEVAPQAKIAELEHEVQKLEKALKEIDES
                     DSEDYVKEGLRAPLQFELDVKQAKLSKLEELSDKIDELDAEIAKLEKDVEDFKNSDGE
                     QAGQYLAAAEEDLVAKKAELEKTEADLKKAVNEPEKPAEETPAPAPKPEQPAEQPKPA
                     PAPQPEKPAEEPENPAPAPQPEKSADQQAEEDYARRSEEEYNRLTQQQPPKAEKPAPA
                     PQPGWKQENGMWYFYNTDGSMATGWLQNNGSWYYLNANGAMATGWLQYNGSWYYLNAN
                     GAMATGWLQYNDSWYYLNANG"
BASE COUNT         3047 a         1215 c         1616 g         2952 t
ORIGIN      
        1 taaatctaat aaattctatt attatagctc ttggtatgat attggcatta attttggtat
       61 tatcaagagt gtatagaaaa tatttttata gagacgatga tgactaaagt ttttatcaat
      121 aatttgggct ccttgtcaac tgtagtggat tgaagaaaag ctaacgtctg gggaagggtt
      181 taaagctttg ctttatcaaa tattgactta cagagttgct ctattgtatt gatgtattct
      241 tagtaaataa tatggtgttt tgaatgaaag atgatcagaa atatttatta gcgggacttt
      301 attcgcttct agttgcaata ttttattttc cattgattga gtccaagggg atttttgtaa
      361 gtatattgat ggcggtttta cttttatatt taatatactt cattgcaaca gtcattcata
      421 ttgtgataat taagtttata agaaaaaaat cttttaagta tttggttcta tatccattta
      481 cttatgatgg gagctggaga tttcaaccta taaacttact ctactttcca gaaatggtga
      541 gagatgtcat tccgattaat ttagttcaag aatattgcca aggacaacct tacggactgt
      601 taaaaaagat gctgaaaaga attcgattgt cacgagagat agctttactc ctggctacca
      661 ttatcgtcta tttttttacg catagaattc tacctctttc agtatttacg ttcatatttt
      721 cttacatatt gctatttgca caatcttatt tgggtggtaa taccgtttgg attggaaata
      781 gaagattaat aatagatgat gaatttgaaa aaatcttgct ttcaaaaagt tatataaaag
      841 aaatatcatc tgcacgatac tcggaatact tgacatgtga atacaaaaac cttacaccaa
      901 tcatattgtt agctattttt gaaaatttgc ttgactccta cttgcttcag aatcagagtg
      961 aggttgactt agatattttt tataaagttt tacctttgct ttataaagaa aaatatacta
     1021 tgggattcaa ttactttgta agtttaaatt atttactata taaggttgga tttttgggaa
     1081 tcatttacga taatgaagca ttaggagatt tgtcaaaaca atatttaaac agaaatattt
     1141 cggaattaca agatggttct ttcgatggcg gtatacaaga tgctgttgcc tctaaacaaa
     1201 tagtagttat aaatgaattt atagcttgtt taaattccag atgcatgcca tcccaatatg
     1261 atagattttt ttataaagat agaccttata ttttttccag aaagagtcct attaaggggt
     1321 gaaaatttgt tacatttgga ttaacaagtg tcctagggat tagaaataac tctagtatag
     1381 ctagatattt ttgagtaact agaaatatca ttaggctacc catatgattg ccagaaaaga
     1441 tggctgatga atcttattta tactgttgca gtaggcattg tctaggataa ataagctatc
     1501 ttgatggggg aaattggaat aattttagta gaaacattaa aggattatgg acaagtagcg
     1561 caggattagg tgatgcaatg tgctaagttg gcttggtgtt agcagtagta ttatttaaca
     1621 atggaaagta gactaaatga aaaataagcg ttattttttt gacacaattt taatgatttt
     1681 actgcttata agcacgatat tttgtgtcag cccagtattt ataaaattgg acatcttagg
     1741 aaccccctct catgccatct taacctttgt attggcgata ccgttattct atattttgtc
     1801 tcaatgctta catactttgc tattactagt ttcctcaatc ttttgtaaat taagaccaat
     1861 ttatttttat tttatatttg tgatcattat aggagctagg aaatactatc gaattctctt
     1921 tcaccaacta atgggattta gtccaggaat agcagtgttt tataaggaga gtcaaacaac
     1981 taagaatctg tttaaatttt actacttctt gtactttaca acactaattt catactattt
     2041 tttctttact tttgtgtatg acaaaccgtt gcttttgcct cttattccat tttctattat
     2101 catagcatta gtacaaaaac tttatagaat tgagaatcaa caattatttc tgttaaaatc
     2161 aaaggtacta acaatactgg aatctaagaa gaattgtgag tttaatcttc aggattatca
     2221 tgaaatttgg aaattgcaat caaaatctga gttgccatgc gtggctttat cttatatcag
     2281 tttgatcaag ccatatcttt cagagagcgt gcgtgaacaa attgatttat tagaagttaa
     2341 gcgatttaaa aaaataaatc atccaatatc actttatggt atgttggatg ttataaaatt
     2401 aaatctatat ttacggcatt ataatgaaaa aaataaatat gaatcaatgt taaagaaaat
     2461 tttagaggta agaccagact ttgttttaat cgagcagaat attgatgata gtttaaatag
     2521 ctcgcaacca ttatctttat ctttagccat ttcagaaatc caacttttgc ttgaagtgta
     2581 tatggggatc aaacatgttt caaccaagtg ataaaaccag aataatattt gccattatag
     2641 gggcaagttg catattagtc agtatgtatc ttattccact tattaaaact gagaataaat
     2701 tttgggaaat acttttattt atattaggtg tattgctaat tggaattgcg ttactaagtc
     2761 aaaaaaaata aattttgaaa tagtattagt gagttcgcaa tcatttattg ctagtggttt
     2821 agaactgtta agtttcaaac aataattgat tttaaacctt aggtaaccta taaaaacaaa
     2881 taaggtagag aaaggatatc ttatctaggt agctaagtga taaaaacaca gtcgtctatc
     2941 acttgttagg aaactatcct aactatgctt aataaaaaag gagaaaataa atggaactcg
     3001 tattaccaaa taattatgtt gttcttgagc aagaagagat gatgtatctt gatgggggat
     3061 tttctattcc gagatggcct gttgcaacag ccattaatat agcttttaat ggtgttttag
     3121 gtggaggagc aatcagtcta gttagaaatt atattcgtaa ttatggtttg cggcgagtta
     3181 caagcgcaat tgctggagca gctgcaagat atgttggggt acgagttgca aatagagtgg
     3241 caggatttgc actgtctgct attaatggat ttgcagcttg gatgtcaatt ggcgatgcta
     3301 ttacaacaat ctgggccaac aatgatgtaa ataggagaga cccaaattta aacgccttgt
     3361 ggtaactaga tatgggtatt aaaatggaaa aaatttttgt tattattttt tttgtatgtc
     3421 tatttatatc atccataact tttttagcct atgattttgt tagcgaagaa ataaaaaagt
     3481 tgattatttg gattaatgtc gtttttttga ttttaatcat agcaatgatg atttatccaa
     3541 aattaagaaa atgataagga cactgtaaaa ttatgatacg taaactaatt gttttcttac
     3601 taatgctccc tctttttgtc ttgtggctag agttgcatgt cctagtgaat aacttactat
     3661 tgaatctaga atctcccctt gattttgtga ttagtatgag tcttgctttc tgtagtttga
     3721 ttttatcaaa aatagtttta gacatactat acgcattgaa agatttatac aagaaagaag
     3781 gtcttattaa gatttttccc tttattttta taagaaggaa aaaagtgaat gtgagattct
     3841 cgccctattt ttcattccat cgtaaaagtt tgtcgcctga tgatttaaga tctaggatta
     3901 tatggagttt tattcttgaa attgctatta tcctagtatt tattttaaaa attccttttg
     3961 caatcatcat gcttactaca atatttttct ggactataat ggatatcaat catctcgttt
     4021 ttaataagac ggaatttctt tttaatcaaa acaaatggca aaaagaagat tcatttgaaa
     4081 gtaatttgca taagatattg atggacaaaa tacaaaaatc agaattaagc tattctgact
     4141 taatgtccct tcttctctat gatgcgatga accaatccac ctttttaacg gatagtgaac
     4201 tttttgagga tattttgaaa aaaatcgaag attctcataa cacccttctg tgtacaggtc
     4261 ttgtcgagtt actgctgtat gagatttcta ttagtaacaa taacaactgg caagaaaagg
     4321 ttgataaaat tagaatacag ctcatcagaa tcaatcaatt agattttttc tattatacaa
     4381 gttggttaag gcaaaatttt gatttctgta tgaatagaga gtatcataaa atgaaatctc
     4441 ggaaattatt actgagtaat aaaaagatag tttaagttcg tcctatttgt aaaacaaatg
     4501 aaacaatttc aactaaggag gagaaaacaa atggaacttg tattaccaaa taattatgtt
     4561 gtgattgatg aagaagtaat gatgtatctt gatgggggag cttatttaag caagcgtgct
     4621 tgtcaaggaa tttgcgcagc agcaggtgta ttggctacag cagcagggaa aatagcttac
     4681 tgtattggat atggtgttct taatagaggt tgtgatatta acgagaaccc ttatccttgg
     4741 gatggattca tatctgcaac agtaagatga gtaatgtaga taagattcga aaaatacaca
     4801 tcatcgtgtg ttgggtgtat atatttttat cattcagggc gattataaat gatacggagt
     4861 attttttgct tattttttta gcttttatct actcaatagt atcactacct ctatattctg
     4921 tgaaaaataa aatagtatct atctgtctag ttataaattc gattctgtta atgagtttcc
     4981 ccattttaat caataagttt ttcccagaaa gttttttgac ttataccgta ttaataagtg
     5041 tttttatcct agagttagca atctttcatt taattaggaa agattttgat attaaattga
     5101 ctaacgaata taagaaaatt agtcagttta gaagcaaggt gtctcaatct ccttggataa
     5161 aatatttaga gatttctagt tttatattaa ctatatttcc atctattctt tatggtaaag
     5221 ttgataatca tgtactgact cttatctttt tgataaaaat ttgtgtagat actacgataa
     5281 aatttttatt catcagatta tttgacacaa gtactttaat gaagaggaga atattttttc
     5341 ttttcgcatt ggatgttata gcttacttat ttttaggata tcttttagtg attcaaaaag
     5401 caggctattt gttttcggtt ttacttcttt tttctaattt ttcagttcca tttatcaaag
     5461 aaaaggaata cgaattattt aaaaatagca agtaatagaa atatggatta aatcttagaa
     5521 cggcttaaaa tcagatatga taaagggaaa tagtcttatc taggtaacta agtgctacaa
     5581 acacaatcga ggatcacttg ttaggattac attttaatca tgcttaataa gaatggagaa
     5641 ttcctatggg gattgtatta ctctgaagtt tcgaatacct tagttctcgt gattttgagc
     5701 tattctagct ttagaatcct tcagaacgta aaattttaag cagtcaaaga cttagaatag
     5761 cctgaaaaca tttattttat agcaattcta ggcttagaat tgctcatata tatgtatttg
     5821 agctgctcga tagttaggac agctctattc tgagaaatct gagctatcaa tgcttcagaa
     5881 tagtatttcg ccaatggttt ttattgaaga ggtgattgtg ttatgatagt ctaaaataaa
     5941 attgatttaa tagagtaaat ggagaatcgt tacatgaaac atttttttgc aggaattggt
     6001 gagataaaac ttgttggcta cttattgtat atatgtgtag gactagcccc tctttttcat
     6061 atatatgtca taggttcgga actgagtttt gtgaaaatag tgttatctat tttgggagtt
     6121 atatttgtaa gtatgttaac tattgctcga atttatcgga cttttctata aagaatagtt
     6181 tggacttaaa ctgtatctaa aaacagaggt tggtcgatta tcagcctctt tcttgtcgtt
     6241 gaaaagagtg agatatattg acttttgaaa aaaagatgtc ataattgagt tgggataaac
     6301 ctaaaagtaa tatagtagat tgaatctgga atagtccgtt atgactgtta aaatatttct
     6361 agaaattaat ttgactttcc taatcgattt gttcacatct tgtttcaatc tactatactt
     6421 tctcgttaaa ccgttcggca attcatggtg acatggacac atagtagtaa gcacactatg
     6481 tggcttggca gagctaaaaa ctgttccctt gcgataagcc taataagcac aacataggga
     6541 gttagagaag ccgactctaa tcaaccactt tgggcaatag tgagaactgc cccgtgcttt
     6601 tttattttga gaaaatatgg agtttgtcgt tgaaattact tgattgtatt ttggactatc
     6661 aagaaagatt caatggaaaa acatgtcaag tatcaacgaa ttataagtat ttagagattt
     6721 tcaaagtgaa tttttgtttg actgatttac atcatttatt tgacttatac aaaatcacac
     6781 gagattatgc tagtcaaaca aaacctgcta ttcaagatgg tgtttttatt ttagaagatt
     6841 ttagaaatat cctatgtaca atgatgtaat cgaaaggata tctttatgtg agtttatcgg
     6901 cgatatcttc tatatctaag ctagcaagtt gttgcatcgt agctaaggat ttatctaaaa
     6961 atactatgaa attggacgtc atattttttg aggataaaaa taaaagatcc gcagttttag
     7021 gtttacgaag agacaaaagc ggagtattta aaccagttac tctacatttt acaagcgcta
     7081 agaaatatgc taaagttcgt aaaacagatg tgaaagaaat gaaatggcta taaagattgt
     7141 ccgcaggctt aagcttgcgt tttttgttgt ttaacgaaat taaaaaacaa gctctctcat
     7201 cggaaatgtt tttataggaa tgaaggaaga tgatgctatg tttaaaaaga gaatcgaaaa
     7261 gggcaaaagt agtgtcttta tctttttgga gtagaagctt atgatataga aatttgtaat
     7321 aaaaatgtaa tataaaacat ttgacaaata tttacggggg gagtatactt aatataagta
     7381 tagtctaaaa atgactatca gaaaagaggt aaatttagat gaataagaaa aaaatgattt
     7441 taacaagtct agccagcgtc gctatcttag gggctggttt tgttacgtct caacctactt
     7501 ttgtaagagc agaagaagct cccgtagcta gtcagtctaa agctgagaaa gactatgatg
     7561 cagcagtgaa aaaatatgaa gctgctaaga aggaatatga ggacggaaaa gctgctcaga
     7621 aaaagtatga agatgatcag aagaaaactg aggagaaagc ggaagaagaa agaaaagctt
     7681 ctgaagaaga acaagctgca aatctgaaat atcaacaaga gttggttaaa tatatacgtg
     7741 aaaatgatcc aacaaaaaaa gctgaagcta agaaagcaat ggatgaggct gagaaagagt
     7801 ataagaaaaa acaaacggaa tttgctgaag ttcgtgcaaa ggtaattcct agcgcggaag
     7861 aattaaaaaa gactagacaa aaagcagaag aggctaaagc aaaagaagca gaacttacta
     7921 aaaaagtaga agaagctgag aaaaaagtta ctgaagccaa acaaaaagtg gatgcagaac
     7981 atgctgaaga agtcgctcct caagctaaaa tcgctgaatt ggaacatgaa gttcagaaac
     8041 tagaaaaagc tctcaaagag attgatgagt ctgattcaga agattatgtt aaagaaggtc
     8101 tccgtgctcc tcttcaattt gaattggatg ttaagcaagc taaactatca aaacttgaag
     8161 agttgagtga taagattgat gagttagacg ctgaaattgc aaaacttgaa aaagatgtag
     8221 aagatttcaa aaactcagac ggtgagcaag ctggacaata ccttgctgca gctgaagaag
     8281 acttagttgc taaaaaagct gaattagaaa aaactgaagc tgaccttaag aaagcagtta
     8341 atgagccaga aaaaccagct gaagaaactc cagctccagc accaaaacca gagcaaccag
     8401 ctgaacaacc aaaaccagcg ccggctcctc aaccagaaaa accagctgaa gagcctgaga
     8461 atccagctcc agcaccacaa ccagagaagt cagcagatca acaagctgaa gaagactatg
     8521 ctcgtagatc agaagaagaa tataatcgct tgacccaaca gcaaccgcca aaagcagaaa
     8581 aaccagctcc agcaccacaa ccaggttgga aacaagaaaa cggtatgtgg tacttctaca
     8641 atactgatgg ttcaatggct acaggttggc tacaaaacaa cggttcatgg tactacctca
     8701 acgctaatgg tgctatggct acaggttggc tccaatacaa cggttcatgg tactacctca
     8761 acgctaatgg tgctatggct acaggttggc tccaatacaa cgattcatgg tattacctaa
     8821 acgctaacgg
//
LOCUS       DAVBDR010000072         8109 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.072, whole genome shotgun sequence.
ACCESSION   DAVBDR010000072 DAVBDR010000000
VERSION     DAVBDR010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8109)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8109)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8109
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.072"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            120..497
                     /locus_tag="VQ540_001898"
     CDS             120..497
                     /locus_tag="VQ540_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001833802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
                     /protein_id="HET2545653.1"
                     /translation="MICQFIRDMLDLPAKNVTILEGSNIHVLPSMPYSAQDFYTSIDV
                     LAELDNGIQVIIEIQVHHQNFFINRLWAYLCSQVNQNLEKIRQREGDTHQSYKQIALV
                     YAIAIVDSNYFSDDLAFHSFIVK"
     gene            732..2123
                     /locus_tag="VQ540_001899"
     CDS             732..2123
                     /locus_tag="VQ540_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013193417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HET2545654.1"
                     /translation="MNKSRLGRGRHGKTRHVLLALIGILAISICLLGGFIAFKIYQQK
                     SFEQKIESLKKEKDDQLSEGNQKEHFRQGQAEVIAYYPLQGEKVISSVRELINQDVKD
                     KLESKDNLVFYYTEQEESGLKGVVNRNVTKQIYDLVAFKIEETEKTSLGKVHLTEDGQ
                     PFTLDQLFSDASKAKEQLIKELTSFIEDKKIDQDQSEQIVKNFSDQDLSAWNFDYKDS
                     QIILYPSPVVENLEEIALPVSAFFDVIQSSYLLEKDAALYQSYFDKKHQKVVALTFDD
                     GPNPATTPQVLETLAKYDIKATFFVLGKNVSGNEDLVKRIKSEGHVVGNHSWSHPILS
                     QLSLDEAKKQITDTEDVLTKVLGSSSKLMRPPYGAITDDIRNSLDLSFIMWDVDSLDW
                     KSKNEASILTEIQHQVANGSIVLMHDIHSPTVNALPRVIEYLKNQGYTFVTIPEMLNT
                     RLKAHELYYSRDE"
     gene            2237..3079
                     /locus_tag="VQ540_001900"
     CDS             2237..3079
                     /locus_tag="VQ540_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HET2545655.1"
                     /translation="MNTYQLNNGVEIPVLGFGTFKAKDGEEAYRAVLEALKAGYRHID
                     TAAIYQNEESVGQAIKDSGVPREEMFVTTKLWNSQQTYEQTRQALEKSIEKLGLDYLD
                     LYLIHWPNPKPLRENDAWKTRNAEVWRAMEDLYQEGKIRAIGVSNFLPHHLDALLETA
                     TIVPAVNQVRLAPGVYQEQVVAYCREKGILLEAWGPFGQGELFDSKQVQEIAANHGKS
                     IAQIALAWSLAEGFLPLPKSVTTSRIQANLDCFGIELSHEERETLKTIAVQSGAPRVD
                     DVDF"
     gene            3352..4113
                     /locus_tag="VQ540_001901"
     CDS             3352..4113
                     /locus_tag="VQ540_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HET2545656.1"
                     /translation="MDNLYLVKDDSQLATFRDFVVRNTEKLKDYQSFLKNELAVCDLP
                     QAVIWSDFNAATQIIRESAVPAYTNNRRMVMAPDLAVWKELYLYQLMDYECSQQTQAI
                     ESHYHSLSENFLLQIVGHELAHWSEHFLDDFDGYDSYIWFEEGMVEYISRKYFLTEEE
                     FQAEKICNQSLVELFQKKYGWHSLNDFGSSTYDKNYASIFYEYWRSFLTVDKLVENLG
                     SVQAVLDSYHLWANTEKTFPLLDWFVQQKLIEKEI"
     gene            4483..5400
                     /gene="glyQ"
                     /locus_tag="VQ540_001902"
     CDS             4483..5400
                     /gene="glyQ"
                     /locus_tag="VQ540_001902"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018163989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HET2545657.1"
                     /translation="MSKKLTFQEIILTLQQFWNDQGCMLMQAYDNEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPSNIQELYLESLEK
                     LGINPLEHDIRFVEDNWENPSTGSAGLGWEVWLDGMEITQFTYFQQVGGLATGPVTAE
                     VTYGLERLASYIQEVDSVYDIEWADGVKYGEIFIQPEYEHSKYSFEISDQEMLLENFD
                     KFEKEAGRALEEGLVHPAYDYVLKCSHTFNLLDARGAVSVTERAGYIARIRNLARVVA
                     KTFVAERKRLGYPLLDEETRVKLLAEDAE"
     gene            5660..7696
                     /locus_tag="VQ540_001903"
     CDS             5660..7696
                     /locus_tag="VQ540_001903"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HET2545658.1"
                     /translation="MTKNLLVELGLEELPAYVVTPSEKQLGEKMAAFLKENRLSFEAI
                     QTFSTPRRLAVRVTGLSDKQSDLTEDFKGPAKKIALDSDGNFTKAAQGFVRGKGLTVE
                     DIEFREIKGEEYVYVTKEEVGQAVEAIVPGVVDVLKSLTFPVSMHWAGNSFEYIRPVH
                     TLTVLLDEQEFDLDFLDIKGSRVSRGHRFLGKETKIQSALSYEEDLRKQFVIADPCER
                     EQMIVDQIKEIEAKHGVRIEIDADLLNEVLNLVEYPTAFMGSFDAKYLEVPEEVLVTS
                     MKEHQRYFVVRDQDGKLLPNFISVRNGNAERLKNVIKGNEKVLVARLEDGEFFWREDQ
                     KLVISDLVEKLNNVTFHEKIGSLREHMIRTGQITVLLAEKAGLSVDETVDLARAAAIY
                     KFDLLTGMVGEFDELQGIMGEKYTLLAGETPAVAAAIREHYMPTSAEGELPESKVGAV
                     LAIADKLDTILSFFSVGLIPSGSNDPYALRRATQGVVRILDAFGWHIAMDELIDSLYA
                     LKFDSLTYENKAEVMDFIKARVDKMMGSTPKDIKEAVLAGSNFVVADMLEAASALVEV
                     SKEEDFKPSVESLSRAFNLAEKAEGVATVDSELFENDQEKALAEAVETLVLSGPASQQ
                     LKQLFALSPVIDAFFENTMVMAEDQAVRQNRLAILSQLTKKAAKFACFNQINTK"
     gene            7738..7995
                     /locus_tag="VQ540_001904"
     CDS             7738..7995
                     /locus_tag="VQ540_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002901318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HET2545659.1"
                     /translation="MDPKKIARINELAKKKKTEGLTPEEKVEQAKLREEYIEGYRRAV
                     RHHIEGIKIVDEEGNDVTPEKLRQVQREKGLHGRSLDDPNS"
BASE COUNT         2555 a         1431 c         1794 g         2329 t
ORIGIN      
        1 gctttctttt ccgaataaat agatagaagc atagaatcta gcaaacctag atttaaaaat
       61 gtgctataat agaaggagga aaaggaggat tctcagacat ccaggtatca gcccaactaa
      121 tgatttgtca atttatccgc gatatgctgg acttgccagc aaaaaatgtg acgattttgg
      181 agggaagtaa cattcacgtc ttgccttcca tgccctactc agcgcaagat ttctatacta
      241 gtatagacgt cttggcggag ttagataatg gaatccaagt tatcatcgaa attcaggttc
      301 atcatcagaa ttttttcatc aatcgcctat gggcttatct gtgcagtcag gttaatcaaa
      361 acctagaaaa aattcgccaa cgtgaaggtg atacccacca gagctacaaa caaatcgcac
      421 tagtatacgc tatcgcaatt gtcgatagta attacttctc agatgaccta gcttttcata
      481 gttttatagt aaaatgaaat gagaacagga caaatcgatc aggacagtca aatcgatttc
      541 taacaatgtt ttagaagtat aggtctacta ttctagcttc aatctactag aaattccata
      601 gatagaaaac tacataatct ctacagatac ggatgttgga gttgatgtaa gatgctttgg
      661 cttgctagag gaattgtgga ttgccaaatt gtatcattga aattattgct caaatttgtt
      721 atgatataaa tatgaataaa agtagactag gacgtggcag acacgggaaa acgagacatg
      781 tattattggc tttgattggt attttagcaa tttctatttg cctattaggc ggatttattg
      841 cttttaagat ctaccagcaa aaaagttttg agcaaaagat tgaatcgctc aaaaaagaga
      901 aagatgatca attgagtgag ggaaatcaga aggagcattt tcgtcagggg caagccgaag
      961 tgattgccta ttatcctctc caaggggaga aagtgatttc ctctgttagg gagctgataa
     1021 atcaagatgt taaggacaag ctagaaagta aggacaatct tgttttctac tatacagagc
     1081 aagaagagtc aggtttaaag ggagtcgtta atcgtaatgt gaccaaacaa atctatgatt
     1141 tagttgcttt taagattgaa gagactgaaa agaccagtct aggaaaggtt cacttaacag
     1201 aagatgggca accttttaca cttgaccaac tgttttcaga tgctagtaag gctaaggaac
     1261 agctgataaa agagttgacc tccttcatag aggataaaaa aatagatcaa gaccagagtg
     1321 agcagattgt aaaaaacttc tctgaccaag acttgtctgc atggaatttt gattacaagg
     1381 atagtcagat tatcctttat ccaagtcctg tggttgaaaa tttagaagag atagccttgc
     1441 cagtatctgc tttctttgat gttatccaat cttcgtactt actcgaaaaa gatgcggcct
     1501 tgtaccaatc ttactttgat aagaaacatc aaaaagttgt cgctctaacc tttgatgatg
     1561 gtccaaatcc agcaacgacc ccgcaggtat tagagaccct agctaaatat gatattaaag
     1621 cgactttctt tgtgcttggg aaaaatgttt ctgggaatga ggacttggtg aagaggataa
     1681 aatctgaagg tcatgttgtt ggaaaccata gttggagcca tccgattctc tcgcaactct
     1741 ctcttgatga agctaaaaag cagattactg atactgagga tgtgctaact aaagtgctgg
     1801 gttctagttc taaactcatg cgtccacctt atggtgctat tacagatgat attcgcaata
     1861 gcttggattt gagctttatc atgtgggatg tggatagtct ggactggaag agtaaaaatg
     1921 aagcatctat tttgacagaa attcagcatc aagtagctaa cggctctatc gttttgatgc
     1981 atgatattca cagtccgaca gtcaatgcct tgccaagggt cattgagtat ttgaaaaatc
     2041 aaggttatac ctttgtgacc ataccagaga tgctcaatac tcgcctaaaa gctcatgagc
     2101 tgtactatag tcgtgatgaa taagcaagaa aaaataggtc tgttagatat ttgacagact
     2161 tattttttac agaatatagt actacttaaa aaatgtttta tgctataatt gatgaataaa
     2221 atagaaggag aagcatatga atacctatca attaaataat ggagtagaaa ttccagtatt
     2281 gggatttgga acttttaagg ctaaggatgg agaagaagcc tatcgtgcag tgttagaagc
     2341 cttgaaggct ggttatcgtc atattgatac ggcggcgatt tatcagaatg aagaaagtgt
     2401 tggtcaagca atcaaagata gcggagttcc acgtgaagaa atgttcgtaa ctaccaagct
     2461 ttggaatagt cagcaaacct atgagcaaac tcgtcaagct ttggaaaaat ctatagaaaa
     2521 actgggcttg gattatttgg atttgtattt gattcattgg ccgaacccaa aaccgctcag
     2581 agaaaatgac gcatggaaaa ctcgcaatgc ggaagtttgg agagcgatgg aagacctcta
     2641 tcaagaaggg aaaatccgtg ctatcggcgt tagcaatttt cttccccatc atttggatgc
     2701 cttgcttgaa actgcaacta tcgttcctgc ggtcaatcaa gttcgcttgg cgccaggtgt
     2761 gtatcaagaa caagtcgtag cttactgtcg tgaaaaggga attttattgg aagcttgggg
     2821 gccttttggt cagggagaac tatttgatag caagcaagtg caagaaatcg cagcaaatca
     2881 cggaaaatcg attgctcaga tagccttggc ctggagcttg gcagaaggat ttttaccact
     2941 tccaaaatct gtcacaacct ctcgtattca agctaatctt gattgctttg gaattgaact
     3001 gagtcatgag gagagagaaa ccttaaaaac gattgctgtt caatcgggtg ctccacgagt
     3061 tgatgatgtg gatttctaga aaatcataaa aagaattgta cattattcta atttttgata
     3121 taatagtcag caggaaagaa agtcttatgg cgttcttcaa gcgagcttgg gatagtggga
     3181 gccaagtagg gcaaaataat gagctggcgc tttctgtagt attttcaaaa acaatgaagt
     3241 aataaattag ggtggaaccg cgtttctgac gcccctaggt taaatcaacc taggattgtc
     3301 ggacgcggtt cttttgctta ttcagtctat tgtgtgaaag aaaggagagc cgtggacaac
     3361 ctttatcttg taaaagacga tagtcaacta gctacatttc gtgattttgt agtaagaaat
     3421 actgaaaagt tgaaagatta tcaatctttt ttaaagaatg aacttgcagt ctgtgattta
     3481 ccgcaagccg ttatttggtc agattttaat gctgctacac agattattag ggaaagcgct
     3541 gttccagcct atacaaataa tagacgaatg gttatggcgc ctgatttagc tgtttggaaa
     3601 gagttgtatt tgtatcaatt gatggactac gagtgttctc agcaaactca agcaatagaa
     3661 agtcactatc attctttatc tgaaaatttc ctcttacaga ttgtaggaca tgagttagct
     3721 cattggtcgg agcatttttt agatgatttt gatggttatg actcttatat ctggttcgaa
     3781 gaggggatgg ttgaatatat tagtcgcaag tatttcttga cagaagagga atttcaagcg
     3841 gaaaaaattt gtaatcaatc tctcgtagaa ctttttcaga agaagtatgg ttggcattca
     3901 ttgaatgatt ttggttcttc gacttatgat aagaactatg caagtatttt ttatgaatac
     3961 tggcgcagct ttttgacagt agataagttg gtagaaaatt taggtagtgt acaagcggtc
     4021 ttagattctt atcatttatg ggcaaataca gaaaaaactt ttcccttgtt agattggttt
     4081 gttcagcaga aattaattga aaaagaaata taaaaactaa aggagtaaac aatgtctaag
     4141 aaattgacat ttcactgcgt cagtggcaga aacctcctta cagtcggact gccccacgct
     4201 cagcactaga gtgcctgagc tagacgcagt actaactcgt cttgcctcgt atgatcgacg
     4261 aggcagactc atgtcgcaag taattatttt ttattaagga gtaaacaatg tctaagaaat
     4321 taacatttca ctgcatcagt ggcagaaacc tccttacagt cggactgccc cacgctcagc
     4381 accctagtgc tgagctagac gcagtactaa ctcgtcttgc ctcgtataat cgacgaggca
     4441 gactcgtgtc gcaagaaatc attttttatt aaggagtaaa caatgtctaa gaaattaaca
     4501 tttcaagaaa ttattttgac tttgcaacaa ttttggaatg accaaggttg tatgcttatg
     4561 caggcttatg acaatgaaaa aggtgcgggg acaatgagtc cttacacttt ccttcgtgct
     4621 atcggacctg agccatggaa tgcagcttat gtagagccat cacgtcgtcc tgctgacggt
     4681 cgttatgggg aaaaccctaa ccgtctctac caacaccacc aattccaggt ggtcatgaag
     4741 ccttctccat caaatatcca agaactttac cttgagtctt tggaaaaatt gggaatcaat
     4801 cctttggagc acgatattcg ttttgttgag gacaactggg aaaacccatc aactggttca
     4861 gctggtcttg gttgggaagt ttggcttgac ggaatggaaa tcactcagtt cacttatttc
     4921 caacaagtcg gtggattggc aactggccct gtgactgcgg aagttaccta tggtttggag
     4981 cgcttggctt cttacattca agaagtagac tctgtctatg atatcgagtg ggctgatggt
     5041 gtaaaatacg gagaaatctt tatccagcct gagtatgagc actcaaaata ttcatttgaa
     5101 atttcggacc aagaaatgtt gcttgaaaac tttgataagt ttgaaaaaga agctggtcgt
     5161 gcattagaag aaggcttggt acaccctgcc tatgactatg ttctcaaatg ttcacatacc
     5221 tttaatctgc ttgacgcgcg tggtgccgta tctgtaacag agcgtgcagg ctatatcgct
     5281 cgtatccgta acttggcccg tgttgtagcc aaaacctttg ttgcagaacg caaacgccta
     5341 ggttacccac ttttggatga agaaacacga gttaaacttt tagcagaaga cgcagaatag
     5401 tgagtaatac tgtactctaa aatcgttaga ggcaagtcga agacttgcta gagggatatg
     5461 caccgccgta ctgttatgtg gggatttttg aaaccttagg ttcaaaaatc agtcagctaa
     5521 atccactttg atgagattgt tggaaatctt gataaattta gcattggatt tccatacaga
     5581 ctcacagagt tagttagcga cgtccccagt acctaaggtg catatcaaaa aagattgaag
     5641 aaaatgtaaa ggaaaaaaca tgacaaaaaa cttattagta gaactcggtc ttgaagaatt
     5701 accagcctat gttgtcacac caagtgaaaa acaactaggc gaaaaaatgg cagccttcct
     5761 caaggaaaac cgcctgtctt ttgaagccat tcaaaccttc tcaacaccac gtcgtttggc
     5821 tgttcgtgtg actggtttat cagacaaaca gtctgatttg acagaagatt tcaagggacc
     5881 agcaaagaaa attgccttgg atagtgatgg aaactttacc aaagcagctc aaggatttgt
     5941 ccgtggaaaa ggcttgactg ttgaagatat cgaattccgt gaaatcaagg gtgaagaata
     6001 tgtctatgtc actaaggaag aagttggtca agcagttgaa gccattgttc ctggtgttgt
     6061 agatgtcttg aagtcattga ctttccctgt cagcatgcac tgggctggaa atagctttga
     6121 atacattcgt cctgtccaca ctttaactgt tctcttggat gagcaagagt ttgacttgga
     6181 tttccttgat atcaagggaa gtcgtgtgag ccgtggccat cgtttcttgg ggaaagaaac
     6241 caaaattcag tcagcattga gctatgaaga agaccttcgt aagcagtttg taatcgcaga
     6301 tccatgtgaa cgtgagcaaa tgattgttga ccaaatcaag gaaattgagg caaaacatgg
     6361 tgtacgtatc gaaattgatg cggatttgct gaatgaagtc ttgaatttgg ttgaataccc
     6421 aactgccttc atgggaagtt ttgatgctaa ataccttgaa gttccagaag aagtcttggt
     6481 gacttctatg aaggaacacc agcgttactt tgttgttcgt gatcaagatg gaaaactctt
     6541 gccaaacttc atttctgttc gtaacggaaa cgcagagcgt ttgaaaaatg tcattaaagg
     6601 aaatgaaaaa gtcttggtag cccgcttgga agacggagaa ttcttctggc gtgaagacca
     6661 aaaattggtg atttcagatc ttgttgaaaa attaaacaat gtcaccttcc atgagaagat
     6721 tggttccctt cgtgaacaca tgattcgtac gggtcaaatc actgtacttt tggcagaaaa
     6781 agctggtttg tcagtggatg aaacagttga ccttgctcgt gcagcagcca tttacaagtt
     6841 tgacttattg acaggtatgg ttggtgaatt tgacgaactc caaggaatta tgggtgaaaa
     6901 atacaccctt cttgctggtg aaactccagc ggtggcagct gctattcgtg aacactacat
     6961 gcctacatca gctgaaggag aacttccaga gagcaaggtc ggcgcagttc tagccattgc
     7021 agacaaattg gatacgattt tgagtttctt ctcagtagga ttgattccat caggttctaa
     7081 tgacccttat gcccttcgtc gtgcaactca aggtgtggtt cgtatcttgg atgcctttgg
     7141 ttggcacatt gctatggatg agctgattga tagcctttat gcattgaaat ttgacagttt
     7201 gacttatgaa aataaagcag aggttatgga ctttatcaag gctcgtgttg ataagatgat
     7261 gggctctact ccaaaagata tcaaggaagc agttcttgca ggttcaaact ttgttgtggc
     7321 agatatgttg gaagcagcaa gtgctctcgt agaagtaagc aaggaagaag attttaaacc
     7381 atctgttgaa tcactttctc gtgcctttaa cctggctgag aaggcagaag gggttgctac
     7441 agttgattca gaactatttg agaatgacca agaaaaagct ttggcagaag cagtagaaac
     7501 actcgtttta tcaggacctg caagtcagca attgaaacaa ctctttgcgc ttagcccagt
     7561 cattgatgct ttctttgaaa atactatggt aatggctgaa gatcaggctg tccgtcaaaa
     7621 tcgtttggca atcttgtcac aactaaccaa gaaagcagct aagtttgctt gttttaacca
     7681 aattaacact aaataaaatt tgataaacgg actttatctt attacaaagg agaagaaatg
     7741 gatccgaaaa aaattgctcg tatcaatgag cttgctaaaa agaaaaaaac agaaggctta
     7801 acaccagaag aaaaagtgga acaagccaaa ctacgtgagg agtacatcga aggttatcgc
     7861 cgcgctgttc gtcaccacat tgaaggaatc aaaattgtgg acgaagaagg aaacgatgtt
     7921 acaccagaaa aactacgcca agtacaacgt gaaaaaggat tacatggccg tagtcttgat
     7981 gacccaaatt cataatatgt actctttctt ttaacaaaga tagatgaaac gataacaaag
     8041 agactagcag tttgtgtttg ctagtctttt ttcgctaaaa aaggaaccat aatggttcct
     8101 aaaaactat
//
LOCUS       DAVBDR010000073         7893 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.073, whole genome shotgun sequence.
ACCESSION   DAVBDR010000073 DAVBDR010000000
VERSION     DAVBDR010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7893)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7893)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7893
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.073"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            101..1078
                     /locus_tag="VQ540_001905"
     CDS             101..1078
                     /locus_tag="VQ540_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HET2545660.1"
                     /translation="MLKLGVIGTGAISHHFIEAAHTSGEYQLVAIYSRKLETAATFAS
                     RYQNIQLFDQLEVFFKSSFDLVYIASPNSLHFAQAKAALSAGKHVILEKPAVTQPQEW
                     FDLIQTAEKNNCFIFEAARNYHEKAFTTIKNFLADKQVLGADFNYAKYSSKMPDLLAG
                     QTPNVFSDRFAGGALMDLGIYPLYAAVRLFEKANDATYHAQQLDNSIDLNGDGILFYP
                     DYQVHIKAGKNITSNLPCEIYTTDGTLTLNTIEHIRSAIFTDHQGNQVQLPIQQAPHT
                     MTEEVAAFAHMIQQPDLNLYQTWLYDAGSVHELLYTMRQTAGVRFEAEK"
     gene            1075..2157
                     /locus_tag="VQ540_001906"
     CDS             1075..2157
                     /locus_tag="VQ540_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HET2545661.1"
                     /translation="MKTKLPTEWQELSDQLGFQEFTPIQTQLFELLLAGENLLGVSQT
                     GTGKTLAYLLPSLLRLQKKKAQQLLILAPNTELAGQIFDVCKTWAEAIGLTAQLFLSG
                     SSQKRQIERLKKGPEILIGTPGRIFELIKLKKIKMMNVETIILDEFDQLLDDSQIHFV
                     EKITHYAPRDHQLVYMSATTKFDQEKIVPNTRTIDLSDQKLDNIQHFYMQVDQRHRVD
                     MLRKLAHVEDFRGLVFFNSLSDLGNAEEKLQYRDILAVSLASDVNVKFRKIILEKFKD
                     NQLTLLLATDLLARGIDIDSLECVVNFDIPRDSETYTHRAGRTGRMGKEGYVITLVTH
                     PEEIKKLKKFASIREIVLKNQELYIK"
     gene            complement(2221..3270)
                     /locus_tag="VQ540_001907"
                     /pseudo
     CDS             complement(2221..3270)
                     /locus_tag="VQ540_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            complement(3654..4850)
                     /gene="tuf"
                     /locus_tag="VQ540_001908"
     CDS             complement(3654..4850)
                     /gene="tuf"
                     /locus_tag="VQ540_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HET2545662.1"
                     /translation="MAKEKYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLARRLPSSV
                     NQPKDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQM
                     DGAILVVASTDGPMPQTREHILLSRQVGVKHLIVFMNKVDLVDDEELLELVEMEIRDL
                     LSEYDFPGDDLPVIQGSALKALEGDSKYEDIVMELMNTVDEYIPEPERDTDKPLLLPV
                     EDVFSITGRGTVASGRIDRGIVKVNDEIEIVGIKEETQKAVVTGVEMFRKQLDEGLAG
                     DNVGVLLRGVQRDEIERGQVIAKPGSINPHTKFKGEVYILTKEEGGRHTPFFNNYRPQ
                     FYFRTTDVTGSIELPAGTEMVMPGDNVTIDVELIHPIAVEQGTTFSIREGGRTVGSGM
                     VTEIEA"
     gene            complement(5761..6630)
                     /locus_tag="VQ540_001909"
     CDS             complement(5761..6630)
                     /locus_tag="VQ540_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000348128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HET2545663.1"
                     /translation="MDFTWALKYATEFLGTAILIILGNGAVANVELKGTKGHQSGWIV
                     IAVGYGMGVMIPALMFGNVSGNHINPAFTLGLAVSGLFPWAQVVPYIIAQVLGAIFGQ
                     ALVVATYRPFYLKTEKPNNILGTFSTISSIDHGTKESRYAATVNGLINEFVGSFVLFF
                     AALGLTKNFFGAEVLQFMKQKAIEAGQTVDFSDLAIKAQVAPHTASGLSVAHLALGFL
                     VMALVTSLGGPTGPALNPARDLGPRLLHAFLPKSVLGEHKGDSKWWYSWVPVVAPIAA
                     AIAAVAVFKFLYL"
     gene            complement(6853..7533)
                     /locus_tag="VQ540_001910"
     CDS             complement(6853..7533)
                     /locus_tag="VQ540_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HET2545664.1"
                     /translation="MVPKTATSTETKTITRIIHYVDKVTNQNVKEDVVQPVTLSRTKT
                     ENKVTGVVTYGEWTTGNWDEVISGKIDKYKDPDIPTVESQEVTSDSSDKEITVRYDRL
                     STPDKPTPEKPEIPSPQEPGTPGEPTPEKPIPQPNPEHPSVPTPNPELPNQETPTPDK
                     PTPEPGTPKAETPVNPDPEVPTYETGKREELPNTGTEANATLASAGIMTLLAGLGLGF
                     FKKKEDEK"
     gene            complement(7491..>7893)
                     /locus_tag="VQ540_001911"
     CDS             complement(7491..>7893)
                     /locus_tag="VQ540_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HET2545665.1"
                     /translation="FKEADTNSASLTGNIVSEGRTVTLVYRESEAPTTATVTANYYKE
                     GSQEKLAESVIKADLAIGSEYTTESKTIEGKTTTEDKEDRVITRKTTYTLVATPANAY
                     QKTVQQLTITTVRMLRKQWFPKQQPLLRRRL"
BASE COUNT         2299 a         1646 c         1489 g         2459 t
ORIGIN      
        1 aaagctaata gcttatttga aattttctcc tctctgttgg atagtcccgt ctatctatgt
       61 tataatgaaa gaaggattta aaatcggaaa aggagtattt atgctaaaat taggtgtcat
      121 cggaactggc gctatcagcc atcatttcat agaagcagcc cataccagtg gagaatacca
      181 actggtcgca atctattcta gaaaactaga aactgcagca acctttgctt ctcgctatca
      241 gaatatccaa ctattcgatc aattagaagt cttcttcaaa tcttcttttg atttagtcta
      301 tatcgccagt ccaaactcct tacattttgc tcaggcaaaa gctgccttgt ctgctggtaa
      361 acatgttatt cttgaaaagc cagctgtcac tcaaccacaa gaatggtttg atttgattca
      421 aacagctgaa aaaaataact gttttatctt tgaagcagct cgtaattatc acgagaaagc
      481 ctttactact atcaaaaact ttttagcaga taagcaagtg ttaggagcag atttcaacta
      541 tgccaaatac tcttccaaga tgcctgactt attggctgga caaacaccaa atgtcttttc
      601 agaccgtttt gctggtggag ccctcatgga tttggggatt tatcccctct atgctgctgt
      661 tcgtcttttt gaaaaagcta atgacgcgac ttaccatgct caacagcttg acaatagcat
      721 tgacctaaat ggagatggta tcctcttcta cccagactat caagttcaca tcaaggctgg
      781 aaaaaacatc acttccaatc ttccttgcga gatttataca acagatggaa ccttgactct
      841 caacacgatt gagcatattc gctcagctat ttttaccgac caccaaggaa atcaagtcca
      901 gcttcctatc caacaggctc ctcatacgat gactgaggaa gtcgctgcat ttgcacacat
      961 gatccagcaa ccagatctga atctctacca aacttggctg tatgatgcag gctctgttca
     1021 tgagctacta tataccatgc gccagactgc tggcgttaga tttgaggcag aaaaatgaaa
     1081 accaaactac cgactgaatg gcaagaactg agtgaccaac tcggtttcca agaattcacc
     1141 cccattcaaa ctcaactatt tgagctcctt cttgctggag aaaacctcct aggagtgagc
     1201 caaaccggaa ctggtaagac cctagcgtat ctcctaccaa gtcttctcag actacaaaag
     1261 aaaaaagccc aacaactctt gattctagca ccaaacacgg aacttgctgg acagattttt
     1321 gatgtatgta aaacgtgggc agaagctatc ggattgactg ctcaactctt cctttcaggt
     1381 tcaagtcaga aacgacaaat tgaacgtctt aaaaaggggc cagaaattct gattggaact
     1441 cctggccgta tctttgaact cattaaactt aaaaaaatca agatgatgaa tgtggaaacc
     1501 atcatcctgg atgaatttga ccaattacta gatgattctc agattcactt tgtagagaaa
     1561 atcactcact acgcacctcg tgaccaccaa ctggtctaca tgagtgccac gaccaagttt
     1621 gaccaagaaa agattgtgcc gaatacacgc actattgatc tctctgatca aaaattggac
     1681 aatatccagc atttctacat gcaggtagac caacgtcatc gagtggatat gctacgaaaa
     1741 ctggctcatg tagaggattt ccgtggtcta gtcttcttca atagcctgtc agaccttggg
     1801 aatgccgagg aaaaactaca gtatcgtgat atattggctg tttccctcgc tagtgatgtt
     1861 aatgttaaat ttagaaaaat catcttagaa aagtttaaag ataaccaact aaccctgctt
     1921 cttgcaactg accttttggc tcgtggaatt gatatcgata gcctagaatg tgtcgtaaac
     1981 tttgatattc ctagagatag cgaaacctac acacaccgtg ctggccgtac tggtcgtatg
     2041 ggcaaggaag gttatgttat cactctcgtc actcatccag aagaaatcaa aaaacttaaa
     2101 aagtttgcaa gtatccgaga aattgtccta aaaaaccaag aactctatat caaataaagc
     2161 cccattgctc tatacacatc cagtgtatgg agctttttta taagcaattc aattttatac
     2221 tcatctgctt tcaaaaagca ttctagtcca tctccgatta acgatggact ttatcacctc
     2281 cttctccaat ccttgtatga catcttgaag ttgattcatg acatcttcca aaattcgaaa
     2341 ggctttattc ttaaatccac gtttacgaat ctctttccac acttgttcaa tggggttcat
     2401 ctctggtgtg tatggaggaa taaatgcaaa accaatatta gtcggaatct ttaagatact
     2461 tgatttatgc catatagcat tgtccataac gagtaaaaaa taatcatctg gataagcttg
     2521 tgaaagcttt tctaaaaagg cgttcatcca ctcagtatta catctaccag ctattaagaa
     2581 aaatgattcg cctgtatggg catcaacagc tccataacaa tagcgaaatt ctcgtatata
     2641 gtgactatgg atatgtggac ctactcctat tggagcccaa caagatccca gtttactgat
     2701 tctaccgaaa ccagcctcat cttggtacat caagcgaacc ttacgaaaac gtctactata
     2761 tttaaaacgc tttcttgtct tcttgaattg agattttatt tttagacgcg acaatggttt
     2821 gagcgtctgc tttcttagga tgttctggac gtggcataat atttcgccaa ccatggcgct
     2881 tcaacagttg atagaaggca tcacgtgtgt aggaacgacc taactccttt ttataagcct
     2941 gaaataaggc atcaattgta acaaattctc ctgcctctgc agccttcaaa tggcgggcaa
     3001 gaaagacttt ctcttcctca actgtcatat atgcatggtt acgaccacca cgtgtttctt
     3061 gaaggagaga gtcgagtccg aactcctcat atttttttac atttcgccaa atcattgttt
     3121 gattacagtc taaaagttct ataatctctt tataagattt gcccatatca gacgaaatag
     3181 aacgatttga agacgtttat gatatttagc tgtacgagag tcttttaaaa gtgttttgat
     3241 ggtttggatt tcttctttaa ttgatttcat attactattg tataatgctt tttgatttta
     3301 gtctagtatt atactcttcg aaaatctctt caaaccgcgt cagcttcgcc ttgtcgtata
     3361 gatgttactg acttcgtcag ttctatctac aacctaaaaa cagtgttttg agcagtctgt
     3421 agctaacttt ctatagtaaa atgaaataag aacaagacaa atcgatcagg acagtcaaat
     3481 cgatttctaa caatgtttta gaagtaaatg tgtactattc tagtttcaat atattatagt
     3541 ttgctctttg attttcattg agtattagtt caatatctaa aaaaagaacc ttgccaagca
     3601 agattctttt agtgtctgac ttaaataatt gttcttctgg gaactaaatc gaattaagct
     3661 tcgatttctg taaccatacc tgaaccaaca gtacgtccac cctcacggat agagaatgta
     3721 gtaccttgtt ctacggcgat tgggtgaatc aactcaacgt cgattgtcac gttatcacca
     3781 ggcattacca tttcagtacc tgctggaagt tcgattgaac ctgtaacgtc agtagtacgg
     3841 aagtagaatt gtggacggta gttgttgaag aatggagtgt gacgtccacc ttcttcttta
     3901 gtaaggatgt agacttcacc tttgaattta gtgtgtgggt tgattgaacc tggtttagcg
     3961 ataacttgtc cacgttcgat ttcatcacgt tgaacaccac gaagaaggac acctacgtta
     4021 tctccagcaa gaccttcgtc aagttgttta cggaacattt caacaccagt aacaactgct
     4081 ttttgagttt cttctttgat accaacgatt tcgatttcgt cgttgacttt aacgatacca
     4141 cggtcgatac gtcctgaagc aactgtacca cgtccagtga ttgagaatac gtcctcgact
     4201 ggaagaagca atggtttgtc agtgtcacgt tctggttctg ggatatactc atcaactgtg
     4261 ttcatcaatt ccataacgat gtcttcgtat ttagagtcac cttcaagagc tttaagtgct
     4321 gaaccttgga taactggaag atcgtcacct gggaagtcgt attctgacaa taggtcacgg
     4381 atttccattt caaccaattc aagcaattct tcgtcgtcaa ccaagtcaac tttgttcatg
     4441 aagacgataa ggtgtttaac accaacctga cgtgaaagaa ggatgtgctc acgagtttgt
     4501 ggcattggtc cgtcagttga agctactaca aggatagctc cgtccatttg agcagcacca
     4561 gtgatcatgt ttttaacgta gtccgcgtgt cctggagcgt cgatgtgagc gtagtgacgt
     4621 ttttcagttt cgtactcaac gtgcgcagtg ttgatagtga taccgcgttc gcgttcttct
     4681 ggagcagcat cgatagacgc atagtcttta ggttggttaa ctgatgaagg caagcgacgt
     4741 gccaaaacag ttgtgatagc tgcagttagg gtagttttac cgtggtcaac gtgtccgata
     4801 gtaccaatgt taacgtgtgg tttactacga tcgtattttt cttttgccat ttgagtaaaa
     4861 gcctccaata aaatatattt tatagataga cagtaggcaa tacagtctaa ctttccttac
     4921 tattttatca aatttcagct aaattgcaag tgttttacaa cgtttttgtg aattattctt
     4981 ggtaaaaatt taactaatta atagaaagta ctaaatagac ttatccttca aggagttttc
     5041 agcattatcc atccactcac ttgctgaaaa tgtaaacagt ctctggttta tatagtaaaa
     5101 tgaaacaaga atagagcaaa tcgatcagga cagtcaaatc gatttctaac aatgttttag
     5161 aagtagatgt gtactattct agtttcaatc tactatacaa cctcaaaact gtgttttgaa
     5221 caacctgcgg ctagcttctt agtttgccct ttgattttca ttgagtataa aattgcagat
     5281 aaaacgataa caatcatagg actcagcaga gtcaatgtag gtcgaagaat agccccccta
     5341 atcgcttatt ttatagcaaa atgaaataga aactgaacat tttgttgagg aaggtaaatc
     5401 aattcctcac aatgtttgag aaagaaggga ggactattcc aacttcaacc cactataaag
     5461 cagacttaca agatagggaa cccatctccg ataatatata gtagaatgaa aactgcacaa
     5521 tttgattgga gaattcaaac caatttctaa caatgtttta gaaacaaggg tctattattt
     5581 caactgcaac ctactatagc ccattgaagc tggaatagcc cactgagact tctaaaccac
     5641 tgctggagag gagtttgttt agagtttctt tcatttccct aaaaaatcaa aaagagagaa
     5701 ccagtctgat cctctcttac ttatagatgg tgctcactca aatgttaaag gagctatttc
     5761 ttagagataa aggaatttga atacagctac tgccgcaatt gctgctgcga taggtgctac
     5821 tactggtacc caagaatacc accattttga atcgccttta tgctcaccaa gaactgattt
     5881 tggaaggaaa gcatgaagga gacgtggtcc caagtcacgg gctgggttca aggcaggtcc
     5941 tgtaggtcct ccaagtgatg ttaccaaagc cataacgagg aatccaagtg ccaagtgagc
     6001 cacagaaagt cctgaagcag tgtgtggagc cacctgtgct ttaatagcca agtcagaaaa
     6061 atcaactgtt tgtcctgctt ctattgcctt ttgtttcatg aattgaagca cttcagcacc
     6121 aaagaagttt ttagtcaaac caagagctgc aaagaacaaa acaaatgaac caacaaactc
     6181 attaatcaaa ccattgacag ttgctgcata gcgactttct tttgtaccat ggtcaatact
     6241 tgaaatagtt gagaaagttc ccaagatgtt atttggtttt tcagttttca agtagaatgg
     6301 acggtatgtt gccacaacta aggcttggcc aaagatagcc cccaagactt gcgcgataat
     6361 gtaaggtacc acttgtgccc aagggaaaag accgctaact gcaagcccta gagtgaaagc
     6421 agggttgatg tgattcccag atacgttacc aaacatcaag gctgggatca taacccccat
     6481 accataacca acagcgatga cgatccagcc actttggtga cctttcgtac ctttaagttc
     6541 aacgttggca actgcaccat tcccaagaat gatcaaaatg gcagttccca aaaattcagt
     6601 ggcatacttc agtgcccatg tgaaatccat ttgctagatt ctccttaaaa ttttttagat
     6661 attccttatt ttatcaattt ttaccctatt tagcaactga tttctggaaa tatttttaaa
     6721 aaaataggat tcatagtttc ccagttcaac gtacttgtaa gcgtttttat tcttcacgaa
     6781 agacctcatt ctcaaaacca ggaaaaagcc cacatctgtg atcttttcct ggttcctaga
     6841 ttctaaaatc tattattttt catcttcttt tttcttgaag aatcctaatc ctagaccagc
     6901 taacaaggtc atgataccag cactagccaa ggtagcatta gcttctgtac ctgtgtttgg
     6961 caattcctct ctcttacctg tctcataagt cggaacttct gggtctggat tcactggagt
     7021 ttcagctttt ggagtacctg gttctggagt tggtttatct ggtgttggag tctcttgatt
     7081 tggtagttct gggtttggtg tcggaacact tggatgctct ggatttggtt gtgggattgg
     7141 tttttctgga gtcggttcac ctggagtacc tggttcctga ggacttggaa tttctggttt
     7201 ttctggagtt ggtttatctg gtgttgataa acggtcatac cttaccgtta tttctttatc
     7261 actagagtct gacgtaactt cttgtgattc aactgttgga atatctggat ctttgtactt
     7321 gtcaatctta ccagatataa cctcgtccca gtttcctgtt gtccattcac cgtaggttac
     7381 aactcccgtg accttgttct cagtttttgt acggcttaag gttacaggtt gaacaacatc
     7441 ttcttttaca ttttggttcg taactttatc aacgtaatga atgatacgcg ttatagtctt
     7501 cgtctcagta gaggttgctg ttttgggaac cactgtttcc tcaacattct cacggtagta
     7561 atagtcaact gttgcaccgt cttctggtac gcatttgcag gagttgctac caaggtgtat
     7621 gttgttttcc ttgtgataac tcggtcttct ttgtcctcag ttgttgtttt cccttcaata
     7681 gtttttgatt ctgtggtata ctcagaacct atcgctaaat cagcttttat aacagactct
     7741 gccaacttct cttggctacc ttctttatag taattggctg ttactgtagc agtggttggc
     7801 gcttcgcttt ctctataaac taaggtcact gttctacctt cgcttacaat attcccagtt
     7861 aaacttgcag aatttgtatc tgcttcttta aaa
//
LOCUS       DAVBDR010000074         7737 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.074, whole genome shotgun sequence.
ACCESSION   DAVBDR010000074 DAVBDR010000000
VERSION     DAVBDR010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7737)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7737)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7737
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.074"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            <1..1039
                     /locus_tag="VQ540_001912"
     CDS             <1..1039
                     /locus_tag="VQ540_001912"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018351.1"
                     /note="Produces ATP from ADP in the presence of a proton
                     gradient across the membrane. Subunit I is part of the
                     membrane proton channel; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HET2545666.1"
                     /translation="IKVMDERFGHSIYIYESETLSDNQDEIPIKLTNHSLIEPFELLT
                     EMYALPKYYEKDPTPVLAPFYFTFFGMMVADLGYGLLLFLGTMLALKIFHLPSETKRF
                     LKFFNILGVAVAIWGGIYGSFFGYELPFHLISTTSDVMIILVVSVVFGFITVFAGLLA
                     SGLQKVRMKKYAEAYNSGFVWCVILLGLLFIAVGMLMPDMRLLFVLGKWVSIFNAVGI
                     LVVSIIQAKSLSGIGAGLFNLYNISSYIGDLVSFTRLMALGLSGASIASAFNLIVGLF
                     PGTLAKLTIGLVLFILLHAINIFLSLLSGYVHGARLIFVEFFGKFYEGGGKPFQPLKA
                     SEKYIKVITKN"
     gene            1055..1531
                     /locus_tag="VQ540_001913"
     CDS             1055..1531
                     /locus_tag="VQ540_001913"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit K"
                     /protein_id="HET2545667.1"
                     /translation="MEHLATYFSTYGGAFFAALGIVLAVGLSGMGSAYGVGKAGQSAA
                     ALLKEQPEKFASALILQLLPGTQGLYGFVIGILIWLQLTPELPLEKGVAYFFVALPIA
                     IVGYFSAKHQGNVAVAGMQILAKRPKEFMKGAILAAMVETYAILAFVVSFILTLRV"
     gene            1565..2146
                     /locus_tag="VQ540_001914"
     CDS             1565..2146
                     /locus_tag="VQ540_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000067169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2545668.1"
                     /translation="MSNLENLRESVIEQAHEKGRMKLLDSKKKIDDEFEMQKSVIVKK
                     KEVEHERKLKELQQKYQIIFQQLKNKERQSTLVSKQKILKELFQSALIEMESWSADKE
                     MEFIYRILERYSQQEVIVTFGERTLAKFNLEQLEKLKFSFPNHLFSEQPISNESGLLI
                     SIGKIDDNYLYKTLIGSISKEESSSIANQIFIN"
     gene            2211..3218
                     /locus_tag="VQ540_001915"
     CDS             2211..3218
                     /locus_tag="VQ540_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000380539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATPase subunit"
                     /protein_id="HET2545669.1"
                     /translation="MDTNLFSKINTTISVKENDFITEDKFQKIIQSKDTETMAFILEA
                     TPYHLSIDVLENPSQTETSLMTKLVNDYRWAYAESPSNKIVTLFALRYVYHNIKVLLK
                     SKAAIKKDFSKLLIPIGIFDIESLKHLVSSLHSDTLPDFMVHEVESIWNEYETFNNIR
                     VLDVGADLAYFKHLKLLSNELDEVLSQVIVAMIDFYNIITVKRGLSQNKSHGDILQLL
                     SDEGSISAKEFIYIVENQEIFVWFNKINPSLDSIFSTYELKMQDATISSSELEFLCDL
                     LLYKILDQGRYNVDGPLVLARYLLGCEFEVKNLRMIISALQNTIPFGSIKERIRPHYG
                     S"
     gene            3208..3528
                     /locus_tag="VQ540_001916"
     CDS             3208..3528
                     /locus_tag="VQ540_001916"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000387939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HET2545670.1"
                     /translation="MEANKYKIGIIGSRDIILPFSMIGFDIFPAYQEQEAINTLRKLA
                     QSDYGVIYITEDIASMILDTIRHYDSQVVPAIILLPTHKQGLNLGLKRIEDNVEKAVG
                     HNIL"
     gene            3591..5366
                     /locus_tag="VQ540_001917"
     CDS             3591..5366
                     /locus_tag="VQ540_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HET2545671.1"
                     /translation="MTQGKIIKVSGPLVIASGMQEANIQDICRVGKLGLIGEIIEMRR
                     DQASIQVYEETSGLGPGEPVVTTGEPLSVELGPGLISQMFDGIQRPLDRFKLATHNDF
                     LVRGVEVPSLDRDIKWHFDSTIAIGQKVSTGDILGTVKETEVVNHKIMVPYGVSGEVV
                     SIASGDFTIDEVVYEIKKLDGSFYKGTLMQKWPVRKARPVSKRLIPEEPLITGQRVID
                     TFFPVTKGGAAAVPGPFGAGKTVVQHQVAKFSNVDIVIYVGCGERGNEMTDVLNEFPE
                     LIDPNTGQSIMQRTVLIANTSNMPVAAREASIYTGITMAEYFRDMGYSVAIMADSTSR
                     WAEALREMSGRLEEMPGDEGYPAYLGSRIAEYYERAGRSQVLGIPEREGTITAIGAVS
                     PPGGDISEPVTQNTLRIVKVFWGLDAPLAQRRHFPAINWLTSYSLYKDSVGIYIDGKE
                     KTDWNSKITRAMNYLQRESSLEEIVRLVGIDSLSDNERLTMEIAKQIREDYLQQNAFD
                     SVDTFTSFAKQEAMLSNILTFADQANHALELGSYFTEIMEGTVAVRDRMARSKYVSED
                     RLDEIKIISNEITHQIHLILETGGL"
     gene            5367..6752
                     /locus_tag="VQ540_001918"
     CDS             5367..6752
                     /locus_tag="VQ540_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000111247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HET2545672.1"
                     /translation="MSVIKEYRTASEVVGPLMIVEQVNNVSYNELVEIQLHNGEIRRG
                     QVLEIHEDKAMVQLFEGSSGINLEKSKIRFAGHALELAVSEDMVGRIFNGMGKPIDGG
                     PDLIPEKYLDIDGQAINPVSRDYPDEFIQTGISSIDHLNTLVRGQKLPVFSGSGLPHN
                     ELAAQIARQATVLNSDENFAVVFAAMGITFEEAEFFMEELRKTGAIDRSVLFMNLAND
                     PAIERIATPRIALTAAEYLAFEKDMHVLVIMTDMTNYCEALREVSAARREVPGRRGYP
                     GYLYTNLSTLYERAGRLVGKKGSVTQIPILTMPEDDITHPIPDLTGYITEGQIILSHE
                     LYNQGYRPPINVLSSLSRLKDKGSGEGKTRGDHAPTMNQLFAAYAQGKKVEELAVVLG
                     ESALSDVDKLYVRFTKRFEEEYINQGFYKNRNIEDTLNLGWELLSILPRTELKRIKDD
                     LLDKYLPLVEV"
     gene            6775..7386
                     /locus_tag="VQ540_001919"
     CDS             6775..7386
                     /locus_tag="VQ540_001919"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000251933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HET2545673.1"
                     /translation="MVRLNVKPTRMELNNLKERLKTAERGHKLLKDKRDELMRRFISL
                     IRENNRLRKEVESYLIDNLKSFAVAKSLKNSLMVEELFSIPSKEIELFIEKENIMSVT
                     VPRMHMNITSQNENSEYSYLSSNSEMDDVFATMNSLIDKLLRLAEVEKTCQLMADEIE
                     KTRRRVNGLEYSIIPNLSETIHYIELKLEEAERANLVRIMKVK"
     gene            complement(7497..>7737)
                     /locus_tag="VQ540_001920"
     CDS             complement(7497..>7737)
                     /locus_tag="VQ540_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2545674.1"
                     /translation="KQVHPLFQTVFKTFLKDKEKIVNALQLHYSNAKLEATNNLIKLI
                     KRNAFGFRNFENFKKRIFIALNIKKERTKFVLSRA"
BASE COUNT         2531 a         1078 c         1580 g         2548 t
ORIGIN      
        1 tataaaagtt atggatgagc gttttggaca ttctatttat atttatgaat cggaaacatt
       61 gtcggataat caagatgaaa tacctatcaa attaacgaat cattctttaa ttgaaccatt
      121 tgaattattg acagaaatgt atgctctgcc caaatattat gagaaagatc ctacacctgt
      181 attagcacca ttttacttta cattttttgg aatgatggtt gctgatttag gctatggttt
      241 actattgttt ttaggaacaa tgttagcatt aaaaattttt catctacctt cagaaactaa
      301 gagattttta aaattcttta atatattagg ggtagccgtt gcaatttggg gtggaatcta
      361 tggctcattt tttggatatg agttgccatt tcatctgata tctacaacct ctgatgtcat
      421 gattatatta gtagtgtcag ttgtgtttgg gtttattaca gtatttgcag gtttgttagc
      481 ttcaggacta caaaaagtaa gaatgaagaa atatgcagaa gcatataatt caggatttgt
      541 gtggtgtgtt attctgcttg gcttgttatt tattgctgtc ggaatgttga tgcctgatat
      601 gagactgtta tttgtattag ggaaatgggt atctattttt aatgctgtgg gaattttggt
      661 tgtttctatt attcaagcca aaagcttgtc aggtattgga gcaggattgt ttaatctata
      721 taacatttca tcttatatag gtgatttagt tagtttcact cgattgatgg cattaggatt
      781 atctggagca agtatagcat cagctttcaa tttaattgtt ggtttgtttc cgggaacatt
      841 ggctaaacta acaattggat tagtattatt cattctttta catgcgatca atatttttct
      901 atcgttacta tcaggatatg ttcatggagc acgtctgata tttgttgaat tttttggtaa
      961 gttttatgag ggtggaggaa aaccatttca acctttgaag gcttctgaga aatatattaa
     1021 ggttattaca aagaattaat ggaggatata tataatggaa catttagcaa cttatttttc
     1081 aacctatgga ggagctttct tcgctgcatt gggaattgta ttggcggttg gattaagtgg
     1141 tatggggtct gcttatggag ttggtaaggc tgggcaatct gccgcagctt tactgaaaga
     1201 acagccagaa aagtttgcct ctgctttgat attgcaatta ctgcccggaa cacaaggatt
     1261 atatggtttt gttattggaa ttttgatttg gttgcaatta actccagaac ttcctttaga
     1321 aaaaggcgtt gcttatttct ttgtagctct tccaattgct attgtaggat acttttcggc
     1381 taagcatcaa ggaaatgtag cagtagcggg aatgcaaatc ttggctaaaa gaccaaaaga
     1441 attcatgaag ggagcaattt tggctgccat ggtagaaacc tatgcaattc ttgcctttgt
     1501 cgtatcattc attttgaccc ttcgtgtata agaaattaat ttgctattca aaggaggtgt
     1561 ctaaatgagc aatttagaaa acttacgaga gtctgttatt gaacaagctc atgaaaaagg
     1621 gcgtatgaaa ttattggatt ccaaaaagaa gattgatgat gaatttgaaa tgcaaaagtc
     1681 ggtcattgta aagaaaaaag aagtggaaca tgaacgaaag ttaaaagaat tacaacagaa
     1741 atatcaaata atttttcaac aattaaaaaa taaggaacgc caatcaacgt tagtatcaaa
     1801 acagaaaata ttaaaagaac tttttcaatc tgctttaata gaaatggaat cttggagtgc
     1861 agataaagaa atggagttca tctatcgaat tctggaacga tattcacaac aagaggtcat
     1921 agtaactttt ggggagcgga ctttagctaa attcaatctg gaacaattag agaaattgaa
     1981 attctctttt ccaaatcatt tatttagtga acagcctatc tcaaatgaat caggcttact
     2041 tatttcaata ggtaaaattg atgataacta tttgtataaa acattaattg gatcgatttc
     2101 taaggaagaa agttcaagta tcgcaaatca aatttttatc aattaaggat gaaattggtt
     2161 aatccttctt agaaatttgg agtattccaa taaaattaga aaggtatttt atggatacta
     2221 atcttttttc aaaaataaat acgacgattt cggtaaaaga aaacgatttt attacagaag
     2281 ataaatttca aaaaattata caatccaaag atacggagac aatggcattt atcttagaag
     2341 caactcccta tcatttatcg attgacgttt tagaaaatcc tagtcagaca gagacttcgc
     2401 taatgacaaa attagtcaat gattatagat gggcctatgc tgaaagtccg tctaataaaa
     2461 ttgtgacttt atttgcttta cgatatgttt atcataatat caaagtttta ttaaaatcta
     2521 aggcggcaat taagaaagat ttttctaaat tattaattcc aatagggatt tttgatatag
     2581 aaagtttaaa acatttagtt tcttccttac attcagatac acttcctgat tttatggttc
     2641 atgaagtaga atcaatttgg aatgagtatg aaacttttaa taatattcgt gtacttgatg
     2701 tcggagctga tctagcatat tttaaacatc tgaaactttt atctaatgag ttagatgagg
     2761 tgctgtctca ggttattgtc gcaatgattg acttttataa tattattact gtaaaacgtg
     2821 gtttatctca aaataagagt catggggata ttttacaatt actttcagat gaaggaagta
     2881 tttctgctaa agaatttata tacattgtag aaaatcaaga aatatttgtg tggttcaata
     2941 aaataaatcc aagcttagat tcaatctttt caacttatga attgaagatg caggacgcaa
     3001 caatttcatc ttctgagtta gaatttttat gtgatttatt attgtataaa attttagatc
     3061 aaggaaggta caatgtagat gggccgttag tacttgctag atatttattg ggatgtgagt
     3121 ttgaagtaaa gaatctcaga atgattatat cagctcttca aaatacaatt ccctttggat
     3181 caataaaaga aaggatacgc ccgcattatg gaagctaata agtataaaat tggcataatt
     3241 ggtagccgtg atattatttt accctttagc atgattgggt ttgatatatt tcctgcctat
     3301 caagaacaag aagctataaa tactctaaga aaattagccc aatctgatta tggtgtcatt
     3361 tatatcactg aagacattgc ttcaatgata ttagatacaa ttcgccatta tgattctcaa
     3421 gttgtgcctg ctattatttt attaccgact cataaacaag gtttaaattt aggattaaaa
     3481 cgtatagagg ataatgtgga gaaagcagta ggacacaata ttttataata atgtacaaaa
     3541 ttgtctgtaa tattattcta taatttttgg acttagtaag gagaataact ttgactcaag
     3601 ggaagattat aaaagtatcg ggacctctag ttattgcatc aggtatgcag gaggctaata
     3661 ttcaagatat ttgccgtgta ggtaagctag ggttaatcgg tgaaattatt gaaatgagaa
     3721 gagatcaggc atctatccaa gtctatgagg aaacatctgg tcttggtccg ggagaacctg
     3781 ttgttacaac tggagaacct ctctcggttg aattaggacc aggattgatt tctcaaatgt
     3841 ttgatggcat acaacgccca ttagatcgat ttaaattggc tactcataat gattttctag
     3901 ttcgtggggt agaagttcca agtttggata gagatattaa gtggcatttt gattccacta
     3961 tagcaattgg tcaaaaagtg agtacgggtg atattctagg aactgtcaag gaaaccgagg
     4021 tagttaatca taaaattatg gttccttatg gagtatctgg cgaagtcgtt tctatcgcat
     4081 ctggcgattt tacaattgat gaagttgtat atgaaataaa aaaattggac ggtagtttct
     4141 ataaaggaac gcttatgcaa aaatggcctg ttcgcaaggc gcgtcctgtt tctaaacgtt
     4201 taatcccaga agaaccatta atcacaggtc aacgagttat tgatacattc tttccagtaa
     4261 ccaaaggggg agcagcagct gttcctggac cgtttggagc aggaaagaca gttgtacaac
     4321 accaagtagc taaattttcc aatgttgata ttgttattta tgtcggttgt ggagaacgtg
     4381 gaaatgaaat gacggatgta ctgaatgagt ttcctgagtt gattgaccct aataccggac
     4441 aatcaattat gcaacggaca gttctgattg ctaatacttc aaatatgcct gttgctgctc
     4501 gtgaggcttc aatttataca ggaattacca tggctgagta ttttcgtgat atgggctact
     4561 ctgtcgccat tatggctgat tcgacttcac gttgggcaga agcactacgt gaaatgtcag
     4621 gacgtctaga agaaatgcct ggtgatgagg gttatcctgc ttatctggga agtcgtatcg
     4681 ctgaatatta tgaaagagcg ggacgttctc aggttctagg gattccagaa cgtgaaggaa
     4741 ctattactgc tattggagct gtatcgccac ccggtggaga tatttcagaa ccagttactc
     4801 aaaacacttt acggattgtg aaagtttttt gggggcttga tgctccgttg gcacagagac
     4861 gtcattttcc tgcaattaac tggcttacat cttattcact ctataaagac agtgtgggaa
     4921 tttatataga tggtaaagag aagacagatt ggaatagtaa aataactcgt gcgatgaact
     4981 acttacaacg ggaatctagt ttagaggaaa ttgttcgtct tgttggaatt gattctctgt
     5041 ctgataatga acgactaacg atggaaattg ctaaacaaat tcgagaagat tatttgcaac
     5101 agaatgcttt tgattcagta gatacattca cttcgtttgc aaaacaagaa gcaatgctaa
     5161 gtaatatcct aacttttgct gatcaggcaa atcatgcttt agagttaggt tcttacttta
     5221 cagagattat ggaaggtacc gtggcagttc gagaccgtat ggcgcgaagt aaatatgttt
     5281 cagaagatag attagatgaa atcaaaatta tttcaaatga gattacacat caaattcatt
     5341 tgatattaga aacaggaggt ctataaatga gtgttataaa agaatacaga actgctagtg
     5401 aagttgttgg gcctcttatg attgttgaac aagtaaataa tgtgtcttac aatgagttag
     5461 ttgaaattca acttcataat ggagaaattc gtcgtggaca agttttagag attcacgaag
     5521 ataaagcaat ggttcaactt tttgaaggat ctagtggaat aaatttagaa aagtctaaaa
     5581 ttcgttttgc tggtcatgca ctagaattgg ctgtatctga ggatatggtt ggtcgtattt
     5641 ttaatgggat gggaaaacca attgatggtg gaccagattt aattccagag aaatatttag
     5701 atattgatgg tcaagctatt aatcctgtat ctagagatta tccagatgaa tttattcaga
     5761 cagggatctc ctctattgat catttgaata ctcttgtacg tggtcaaaaa ttaccagtat
     5821 tttcaggttc gggcttacct cataatgaat tagcagctca gatagcaaga caagcgactg
     5881 ttttaaattc tgatgaaaat tttgcggttg tatttgcagc aatgggtatt acttttgaag
     5941 aagctgagtt ttttatggaa gaactcagaa aaacaggagc gatcgatcgt tcagtcttat
     6001 ttatgaactt ggcaaatgat cctgcaattg agcgtattgc aactccccgc attgctttaa
     6061 ccgcggcaga gtatctagct tttgaaaaag atatgcacgt tctagttatc atgacggata
     6121 tgactaacta ttgtgaagcg ttacgtgaag tctcggcagc gcgccgtgaa gttccaggta
     6181 gacgaggcta tccgggatat ttatatacaa atttatcaac tctatatgaa agggctggtc
     6241 gcttagttgg taaaaaaggt tcagtgacac agattcctat tttaacaatg ccagaagatg
     6301 acataacaca tccaattcct gatttaactg gatacattac tgaagggcaa attattttgt
     6361 ctcatgagtt gtataatcaa ggttatcgtc caccaatcaa tgttttatct tctctctctc
     6421 gattaaaaga taagggatct ggagaaggta aaactcgtgg agatcatgct ccaactatga
     6481 atcaactgtt tgcagcctat gcccaaggga aaaaggttga agagttagca gtagtattag
     6541 gagaatcggc tttatctgat gtagataaat tgtatgtgag atttacaaag cgttttgaag
     6601 aagagtacat caaccaagga ttttataaaa atcgaaatat agaagatacg ttgaatcttg
     6661 ggtgggaatt actatcaatt cttcctagaa cagagttaaa acgtatcaaa gatgatttgc
     6721 ttgataaata tttacctttg gtagaagttt aatccagaaa tggagtgatt atctatggta
     6781 cgtttgaatg taaaaccaac tcgtatggaa ttgaataact taaaggaacg tttgaaaaca
     6841 gctgaacgtg gacataagtt attaaaggat aaaagagatg aattgatgag gcgatttatt
     6901 tctttgattc gtgagaataa tcgacttcgg aaagaagtag aaagttatct aattgataat
     6961 ctaaaatctt ttgcagttgc taaatcatta aagaactctc taatggtgga ggaattattt
     7021 tcaattccat cgaaagaaat tgaattattt attgagaaag aaaatatcat gagtgtaaca
     7081 gttcctagaa tgcatatgaa tattacttct caaaatgaga acagtgaata cagctattta
     7141 tcttctaata gtgaaatgga tgatgtattt gctacaatga atagtttaat tgataaatta
     7201 ctaagactgg cagaagttga aaaaacgtgt cagttaatgg ctgatgaaat agaaaaaaca
     7261 cgtagacgtg taaatggttt agaatattcg attattccaa acttgtcgga aactattcat
     7321 tatatagaat tgaaactaga ggaggcagaa agagccaatt tagttcgtat tatgaaagtg
     7381 aagtagttcc tttatttaga tttttaatta gatgaacaaa tatcagcttg gataaggcgg
     7441 taagcctttc taagcttttt taggctcttt gtcaactgta gtgggttgaa aaaaagctaa
     7501 gctcgagaaa ggacaaattt cgtcctttct tttttgatat tcagggcgat aaaaatccgt
     7561 tttttgaagt tttcaaagtt ccgaaaacca aaggcattgc gcttgataag tttgatgaga
     7621 ttattggtcg cttccaattt ggcgttagaa tagtgtagtt gaagggcgtt gacgattttc
     7681 tctttgtcct ttagaaaggt tttaaagaca gtctgaaaaa gaggatgaac ctgcttt
//
LOCUS       DAVBDR010000075         7220 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.075, whole genome shotgun sequence.
ACCESSION   DAVBDR010000075 DAVBDR010000000
VERSION     DAVBDR010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7220)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7220)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7220
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.075"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            231..645
                     /locus_tag="VQ540_001921"
                     /pseudo
     CDS             231..645
                     /locus_tag="VQ540_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720030.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(684..1127)
                     /locus_tag="VQ540_001922"
     CDS             complement(684..1127)
                     /locus_tag="VQ540_001922"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HET2545675.1"
                     /translation="MKIIIQRVKKAQVSIEGQIQGKINQGLLLLVGVGPEDQEEDLDY
                     AVRKLVNMRIFSDAEGKMNLSVKDIEGEILSISQFTLFADTKKGNRPAFTGAAKPDMA
                     SDFYDAFNQKLAQEVPVQTGIFGADMQVELVNNGPVTIILDTKKR"
     gene            complement(1157..3379)
                     /locus_tag="VQ540_001923"
     CDS             complement(1157..3379)
                     /locus_tag="VQ540_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019316080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HET2545676.1"
                     /translation="MPKEVNLTGEEVVALTKEYLTEEDVHFVHKALVYAVECHSGQYR
                     KSGEPYIIHPIQVAGILAKLKLDAVTVACGFLHDVVEDTDATLDDLEREFGPDVRMIV
                     DGVTKLGKVEYKSIEEQLAENHRKMLMAMSEDIRVILVKLSDRLHNMRTLKHLRKDKQ
                     ERISKETMEIYAPLAHRLGISSVKWELEDLSFRYLNPTEFYKITHMMKEKRREREALV
                     DEVVTKLEEYTTERHLKGKIYGRPKHIYSIFRKMQDKRKRFEEIYDLIAIRCILDTQS
                     DVYAMLGYVHEFWKPMPGRFKDYIANRKANGYQSIHTTVYGPKGPIEFQIRTKEMHEV
                     AEYGVAAHWAYKKGIKGQVNSKESAIGMNWIKEMMELQDQADDAKEFVDSVKENYLAE
                     EIYVFTPDGAVRSLPKDSGPIDFAYEIHTKVGEKATGAKVNGRMVPLTTKLKTGDQVE
                     IIANPNSFGPSRDWLNMVKTSKARNKIRQFFKNQDKELSVNKGREMLMAQFQENGYVA
                     NKFMDKRHMDQVLQKTSYKTEDSLFAAIGFGEIGAITVFNRLTEKERREEERAKAKAE
                     AEELVKGGEVKVENKETLKVKHEGGVVIEGASGLLVRIAKCCNPVPGDDIVGYITKGR
                     GVAIHRVDCMNLRAQENYEQRLLDVEWEDQYSSSNKEYMAHIDIYGLNRTGLLNDVLQ
                     VLSNTTKNISTVNAQPTKDMKFANIHVSFGIANLSTLTTVVDKIKSVPEVYSVKRTNG
                     "
     gene            3790..4032
                     /locus_tag="VQ540_001924"
     CDS             3790..4032
                     /locus_tag="VQ540_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2545677.1"
                     /translation="MTRFEEIFEEYKNPQDTFFYPLVYKENTYEKTAISIFALLMLGV
                     CCLFLFSQQSYKKLVQYYANDQNLPSRITYSEYSDK"
     gene            4372..5001
                     /locus_tag="VQ540_001925"
     CDS             4372..5001
                     /locus_tag="VQ540_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HET2545678.1"
                     /translation="MKIHKTVNPVAYENTYYLEGEKHLIVVDPGSHWEAIRQTIEKIN
                     KPICAILLTHAHYDHIMSLDLVRETFGNPPVYIAESEASWLYTPVDNLSGLPRHDDMA
                     DVVTKPAEHTFVFHEEYQLEEFRFKVLPTPGHSIGGVSLVFPDAHLVLTGDALFRETI
                     GRTDLPTGSMEQLLHSIQTQLFTLPNYDVYPGHGPATTIAHEKAFNPFF"
     gene            complement(5124..7016)
                     /gene="pepO"
                     /locus_tag="VQ540_001926"
     CDS             complement(5124..7016)
                     /gene="pepO"
                     /locus_tag="VQ540_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase PepO"
                     /protein_id="HET2545679.1"
                     /translation="MTRYQDDFYDAINGEWQQTAEIPADKSQTGGFVDLDQEIEDLML
                     ATTDKWLAGEEVPEDAILENFVKYHRLVRDFDKREADGITPVLPLLKEFQELETFADF
                     TAKLAEFELAGKPNFLPFGVSPDFMDARINVLWASAPSTILPDTTYYAEEHPQREELL
                     TLWKESSANLLKAYDFSDEEIEDLLEKRLELDRRVAAVVLSNEESSEYAKLYHPYSYE
                     DFKKFAPALPLDDFFKAVIGQLPDKVIVDEERFWQAAEQFYSEEAWSLLKATLILSVV
                     NLSTSYLTEDIRVLSGAYSRALSGVPEAKDKVKAAYHLAQEPFKQALGLWYAREKFSP
                     EAKADVEKKVATMIDVYKERLLKNDWLTPETCKQAIVKLNVIKPYIGYPEELPARYKD
                     KVVNETASLFENALAFARVEIKHSWSKWNQPVDYKEWGMPAHMVNAYYNPQKNLIVFP
                     AAILQAPFYDLHQSSSANYGGIGAVIAHEISHAFDTNGASFDENGSLKDWWTESDYAA
                     FKEKTQKVIDQFDGQDSYGATINGKLTVSENVADLGGIAAALEAAKREADFSAEEFFY
                     NFGRIWRMKGRPEFMKLLASVDVHAPAKLRVNVQVPNFDDFFTTYDVKEGDGMWRSPE
                     ERVIIW"
BASE COUNT         1985 a         1681 c         1378 g         2176 t
ORIGIN      
        1 ttatcatttt atgacaaaca tactatcgtt aaatgctgat ttaatcgaaa ttttgagtta
       61 taaactcctc agtttcgaac tcaaaattag ccgtgcagga taggataccc ttcataaact
      121 tatataacta ctttaatacc ttaaaaagct aataaaataa ggaatatcta agcaatatac
      181 attctaaaat acctgtacgg gagtgtctct aaagaaaagg aggttttagc atgaaaaaaa
      241 tcatcttcat caaaaccatt caactccttg tcattgatgg aatcatgctg gcatttttga
      301 catttaaaag gggggcttac ttgggactgg attttgattt atagtggttg gctcattttc
      361 tttcatcctg tgctattgac ctatctttca aaccaacttt gtgaccactt tagtcaactc
      421 tattcccaga ttagaccgag attctggcgt tttgctttac aaattctcct atgggatagc
      481 ctgatgattc tctccttggt gtctttaagt gatattccac ttttccttca gggaactctc
      541 ctcatcctag gacatctcat cccttcctat cgcatctgcc aaagcctgaa aagagacttc
      601 ccccaagcat atcaagaacc gatttctttt tggagtattt tatgatcgat gagaaagacc
      661 aagccgactg ggcttggtct ttcttatctc tttttagtat ctaggataat ggtaacaggt
      721 ccgttattaa ccagctcaac ctgcatatct gctccaaaga tacctgtctg aacgggcact
      781 tcttgcgcta atttttgatt gaaagcatca tagaagtctg atgccatatc aggtttagct
      841 gcccctgtaa aggctggacg attgcctttc ttagtatccg caaagagggt aaactgagaa
      901 atagagagga tttctccttc aatatctttg acagacaggt tcatcttgcc ttctgcgtct
      961 gaaaaaatcc gcatattgac cagttttctc acagcatagt ccaaatcttc ctcttggtcc
     1021 tctggtccaa caccaaccag caataaaagt ccctgattga tttttccctg aatctggcct
     1081 tctatactca cttgggcttt tttaacccgt tggataatga ttttcataat agcctttcta
     1141 gtaagagcta ggacaactag ccgttggtcc gtttgacaga gtaaacttct ggcacactct
     1201 taattttatc gacaaccgtg gtcagtgtag agaggttggc aataccgaag gacacatgga
     1261 tattagcaaa cttcatatcc ttggttggtt gggcattgac cgttgaaata ttcttggttg
     1321 tatttgaaag aacttgcagt acatcgttca acagtcctgt acggttgaga ccgtagatat
     1381 cgatatgggc catatactcc ttatttgagc tagagtactg gtcttcccat tccacatcaa
     1441 ggagacgttg ctcgtagttt tcttgggcac gcaggttcat acagtccaca cggtgaatag
     1501 ccacaccacg acccttggta atgtagccaa caatatcgtc accaggcacg gggttacaac
     1561 acttagcaat ccgcactagg agaccagaag caccttcaat aaccactccc ccctcatgct
     1621 tgaccttgag agtttcttta ttttcaacct tgacctcgcc acctttgaca agctcctctg
     1681 cctcagcctt ggccttggca cgctcttcct cacggcgttc cttttcagtc agacggttaa
     1741 agacggtaat cgcaccgatt tccccaaaac caatggccgc aaagagggag tcttctgtct
     1801 tgtaactggt cttttgcaga acttgatcca tgtggcgctt gtccataaat ttatttgcca
     1861 catagccatt ttcttggaac tgagccatca gcatctcacg acccttgttg acagacaatt
     1921 ccttatcttg gtttttaaag aactggcgaa tcttattgcg cgccttgcta gtcttgacca
     1981 tattgagcca gtcacggcta ggtccaaagg agttcgggtt ggcgataatt tcaacctgat
     2041 cccctgtctt taacttggtt gtcagtggaa ccatgcggcc attgaccttg gcaccagttg
     2101 ctttttcacc gaccttggta tggatttcgt aggcaaaatc aatcggtcct gaatctttgg
     2161 gaagagaacg gacagctcca tctggggtaa aaacgtaaat ctcctcagcc agatagtttt
     2221 ccttaacaga gtccacaaat tccttagcat catcagcctg gtcttggagc tccatcatct
     2281 ccttgatcca gttcattcca atagctgatt ccttgctgtt aacttgcccc tttatacctt
     2341 tcttataagc ccagtgagcc gcaaccccgt actcagccac ctcgtgcatt tccttggttc
     2401 gaatctggaa ttcaatcggc ccttttggtc cataaacagt cgtatggata gactgataac
     2461 cattagcctt gcggttggca atatagtctt tgaagcgacc tggcatcggt ttccaaaatt
     2521 catgcacgta accaagcatg gcataaacat cactttgggt atctaaaata caacgaatag
     2581 caatcagatc atagatttcc tcaaaccgtt ttctcttgtc ctgcattttg cggaaaattg
     2641 agtaaatatg cttgggacga ccataaatct tccctttcaa gtgacgttct gtcgtatact
     2701 cctctaattt tgtgactacc tcatccacca aggcctcacg ctccctgcgc ttttccttca
     2761 tcatatgggt aatcttgtaa aactccgttg gattgagata acggaaagac aagtcttcta
     2821 attcccattt gacactggaa atccccaaac gatgggcaag cggggcatag atttccatgg
     2881 tttctttgga aatacgctcc tgcttgtctt ttcgaagatg tttcagggtc cgcatattgt
     2941 gcaagcggtc agacagtttg accaaaataa cgcggatgtc ctcagacatg gccatgagca
     3001 tcttgcgatg attttccgct aattgctcct cgatcgattt gtactcgacc ttgccaagct
     3061 tggtaactcc gtcaacaatc atccgcacat caggaccaaa ctctctttcc aaatcgtcca
     3121 aagtcgcatc tgtatcttcc accacatcat gcaagaatcc acaagctact gttacagcat
     3181 ccagctttag cttagctaaa atacctgcca cttggatagg gtgaatgata taaggctcgc
     3241 ctgatttgcg atattgacca ctgtggcatt caacagcata gaccaaggcc ttatggacaa
     3301 aatgaacatc ctcttccgtt aaatattctt tggttaaagc gacaacttct tcgcctgtta
     3361 aattcacttc tttcggcatc tctactctcc aattcttcct accattttat cactttttta
     3421 agaatatgaa aactagattg gaacagaata agaaaaaaat aattcaaaat tgcttgataa
     3481 ttctgaatta ttggcccata atatactacg aagttagatt ttaaacttag gtgatagaag
     3541 gagagataga agaacggaaa ccatattgta acccaaagac tttctgattt ccccaattcc
     3601 attgaagata cgaaagataa acggtggaac tcgtatcaca tacactggta ccttgactgg
     3661 attttggaat taatactcaa tgaaaatcaa agagcaaact aggaaactag ccacaggttg
     3721 ctcaaagcac tgctttgagg ttgtagataa gactgacaaa gtcagtcaca tatatacggc
     3781 aaggcgacgt tgacgcggtt tgaagagatt tttgaagagt ataaaaatcc tcaagatact
     3841 ttcttctatc ctttagttta taaggagaat acctatgaaa aaactgctat ttctatcttt
     3901 gctctcctaa tgttaggagt ttgctgcctg ttcctattca gccagcaaag ctataaaaaa
     3961 ctcgttcaat actatgctaa cgaccagaac ctgcccagta ggataactta tagtgaatat
     4021 agcgacaaat gagaagccaa ctacggtagc actctaaaca tcacgtctat caaacaagct
     4081 aatgacggag tttatgcaac ctatgaaggg caattgacac ctttccaata ttgataaatt
     4141 gataaccagc ctgtcttcat ctagtcatgc tggtttttaa gttcatttta aatccttacc
     4201 tattctccct aactgtgcta tacttaattt atactcaatg aaaatcaaag agcaaactag
     4261 aaagctagcc gcaggctgtt caaagcactg ctttgaggtt gcagataaag ttgacgcggt
     4321 ttgaagagat tttcgaagag tattagtaca ttctttgaga ttggagttag tatgaaaatc
     4381 cataaaaccg tgaatcctgt tgcctatgaa aatacctatt atctagaagg cgaaaagcac
     4441 ctcatcgtcg tcgatcctgg tagtcattgg gaagccattc gtcagacaat cgagaagatc
     4501 aacaaaccga tctgtgctat tctcttgacc cacgcccatt atgaccatat catgagtctg
     4561 gacttggttc gcgagacgtt tggcaatcct cctgtctata tcgcagagag cgaagccagc
     4621 tggctctaca ctcctgtcga taatctctcc ggtctccctc gccacgatga tatggcagat
     4681 gtggtcacaa aacctgcaga acacaccttt gtctttcacg aagaatacca actagaggaa
     4741 tttcgtttta aggttctacc gaccccaggg cactctatcg gtggtgtttc cctagtcttt
     4801 cctgatgctc acctagtctt gacgggagat gctctattcc gcgaaactat cggacggacc
     4861 gaccttccga ctggtagcat ggagcaactc cttcatagta tccagaccca actcttcacc
     4921 ctaccaaact acgatgtcta tccaggacat ggtccagcta ctactatcgc tcacgaaaag
     4981 gccttcaatc cctttttcta gcaagatgat gacaatcgaa atttaagtaa actatccagc
     5041 aaatctttct attacaaaag gcatcctatc aaggttttca cacgtgattg gatgcctttt
     5101 ttctgatgac tagatttttt gtattaccaa ataatcacgc gctcctctgg tgaacgccac
     5161 attccgtctc cttctttgac atcataggtt gtaaagaaat cgtcgaagtt tggtacttgc
     5221 acattgacac ggagtttggc tggtgcgtgc acatcgacgc tagccaaaag tttcataaat
     5281 tctggtcgac ctttcatgcg ccagatgcga ccgaagttgt agaagaactc ttctgctgag
     5341 aagtctgctt ctctcttagc tgcttcaagc gctgctgcga ttcctcccaa gtcagccacg
     5401 ttttctgata cagtcaattt accgttaatg gttgctccat aagaatcctg tccatcaaat
     5461 tggtcaatga ctttttgtgt tttctccttg aaggcagcat agtcgctctc tgtccaccaa
     5521 tccttgaggc taccattttc gtcaaaggaa gccccgttag tatcaaaggc gtgggaaatt
     5581 tcatgggcaa tcactgcccc aataccaccg tagttagcag aagatgactg atgcaagtca
     5641 tagaaaggcg cctgtaaaat ggccgctgga aagacaatca ggttcttctg aggattgtag
     5701 taggcattga ccatatgagc aggcatgccc cattccttat agtctacagg ctggttccac
     5761 ttactccaac tgtgcttgat ttccacacgc gcaaaggcta gagcattctc aaaaagactg
     5821 gcagtttcat tcactacctt atccttgtaa cgtgcaggca attcttctgg atagccaata
     5881 taaggtttga tcacattgag cttcacgata gcctgtttac aggtttctgg agtgagccag
     5941 tcattcttaa gcagacgctc cttatagaca tcaatcatgg ttgccacttt tttctccaca
     6001 tccgccttgg cttctggaga gaacttctca cgggcgtacc aaagccccag ggcttgcttg
     6061 aaaggttcct gtgctagatg ataagctgct ttgaccttat cttttgcctc tggaactcca
     6121 gaaagggcac ggctgtaggc accagacaaa acacggatat cctctgttaa atagctggtt
     6181 gaaagattga caacactcaa aatcaaggtt gctttaagga gagaccaggc ttcctcactg
     6241 taaaattgct ctgctgcttg ccagaaacgt tcctcgtcta caataacctt gtctggtaat
     6301 tgcccaataa ctgctttgaa gaagtcatcc aaaggtaggg caggcgcgaa tttcttgaaa
     6361 tcttcgtaag aatatggatg atagagttta gcatattctg aactttcttc attagagagc
     6421 accactgccg caactcggcg gtccaattca agtctttttt ctagcaagtc ttcaatttct
     6481 tcatcagaga aatcataagc cttgaggaga tttgcgctgc tttctttcca aagagtcaag
     6541 agctcttcgc gctgaggatg ttcttctgca tagtaggtcg tatctggcaa gattgtgctt
     6601 ggagcgctag cccatagaac attgattcta gcatccataa agtctggcga tacaccaaaa
     6661 ggaaggaagt ttggttttcc tgcaagctca aactctgcta gtttagctgt aaaatccgca
     6721 aaagtttcca attcttggaa ttctttaagg agtggtaaga caggtgtgat accgtcagct
     6781 tctctcttgt caaaatcacg aactaggcgg tggtatttga caaagttttc caagatagca
     6841 tcctcaggca cttcttcacc tgctaaccac ttgtctgttg tcgccagcat caggtcttca
     6901 atttcctggt ctaaatcaac aaaacctcct gtttgagact tatctgctgg gatttcagct
     6961 gtctgttgcc attctccatt gatagcatca taaaaatcat cttgataacg tgtcatcttg
     7021 ttctcgcttt catttgtatt tgcatttatc ttaacaaaaa tcactaggga atgcaattaa
     7081 taaccattta actattattt tttagctatt ataaaaaacc tttccatgat aaaacgcata
     7141 attccaagtt ttttacactt gatactatgc gttttataat ttagaaattt atcctgaaag
     7201 ttatctttag aatctatttt
//
LOCUS       DAVBDR010000076         7162 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.076, whole genome shotgun sequence.
ACCESSION   DAVBDR010000076 DAVBDR010000000
VERSION     DAVBDR010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7162)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7162)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7162
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.076"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            complement(741..1001)
                     /locus_tag="VQ540_001927"
     CDS             complement(741..1001)
                     /locus_tag="VQ540_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2545680.1"
                     /translation="MRERSATGAQGLSKSIKKHLNDLTRLTASLLGDEKLSAITSSSA
                     VKADIHRFVIELEPVKSTILQNDDISLDQNEIFEILKNFLDG"
     gene            complement(1060..1611)
                     /locus_tag="VQ540_001928"
     CDS             complement(1060..1611)
                     /locus_tag="VQ540_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001111259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2545681.1"
                     /translation="MPANTKVIFQEMFADFQNYYVLIGGTATSIVLDSQGFKSRTTKD
                     YDMVIIYEVKNKEFYTTLNHFLELGEYQGSQKDEKAQLFRFTTTNPEFPSMIELFSIL
                     PEYPLKKDGREIPLHFDQDASLSALLLDEDYYNILVHEKETIQGYSVLSNCGLYSSKI
                     SSNHVSFHLQPQNSVLSSLQLAS"
     gene            complement(1601..1798)
                     /locus_tag="VQ540_001929"
     CDS             complement(1601..1798)
                     /locus_tag="VQ540_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000890145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2545682.1"
                     /translation="MLEIWKYRPFVSEFWNDFKNNHDKQFVDPISLYLTLKDDDDPRI
                     EEESEALENMILQYLGEDDAS"
     gene            complement(1802..2386)
                     /locus_tag="VQ540_001930"
     CDS             complement(1802..2386)
                     /locus_tag="VQ540_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001101186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2545683.1"
                     /translation="MNVKKIMSIFQSFYVDVSIEELTLTLPISFVKRFEYTQMTFHKE
                     SFLLIKEKRRGSLSSFVTQARTMGEKANMDVVLVFSKLSDSEKKQLLQARVPFVDFKG
                     NLFFPPLGLVLNANDTEIPKELTPSEQLTWIAFLLPDGDIKQIKSVSNLLYGGAYALS
                     HSTFLAETDENTSYVIWQRKFNQLSLPLSQHVLK"
     gene            complement(2794..3219)
                     /locus_tag="VQ540_001931"
     CDS             complement(2794..3219)
                     /locus_tag="VQ540_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000204059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2545684.1"
                     /translation="MTSRVFIDADCISAFLWVGTEHLLEKLYSGKIVIPQEVYDEINI
                     PTIPHLKSRIDQLVTKGSAEIVSIDIGTEEYALYRDLTRNYDSNKIIGKGEATSIFLA
                     KKHNGILGSNNLRDVKPYVEEFSLEHMTTGDILIEAFKA"
     gene            complement(3212..3706)
                     /locus_tag="VQ540_001932"
     CDS             complement(3212..3706)
                     /locus_tag="VQ540_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004236771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2545685.1"
                     /translation="MKKSSVSLILIGEGDETERKADQFASYFLIFPSSLYRMVEEIRE
                     NANRTHLEVEDIIKLGQFYGISHKAMLYRLRNDGYLDAEEIKNMDISVIETASRLGYD
                     TSLYRPLSESKKEMVLGHYIKSTEQLLENNRISQGKYEELLLDAFRYDIVYGLDEEGE
                     LSFD"
     gene            complement(3752..3958)
                     /locus_tag="VQ540_001933"
     CDS             complement(3752..3958)
                     /locus_tag="VQ540_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2545686.1"
                     /translation="MDLSNKASNLRKKLGADGESPIDIFKLVQKIENLTLVFYGLGKN
                     ISGVCYKGTQFSLIAVNSDMPLGR"
     gene            complement(3945..4106)
                     /locus_tag="VQ540_001934"
     CDS             complement(3945..4106)
                     /locus_tag="VQ540_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET2545687.1"
                     /translation="MNMINVCDVGKRIKELRISSNLTQDKIAEYLSLNQSMIAKMEKG
                     ERNITNGFK"
     gene            complement(4471..5427)
                     /gene="lytA"
                     /locus_tag="VQ540_001935"
     CDS             complement(4471..5427)
                     /gene="lytA"
                     /locus_tag="VQ540_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase LytA"
                     /protein_id="HET2545688.1"
                     /translation="MEINVSKLRTDLPQVGVQPYRQVHAHSTGNPHSTVQNEADYHWR
                     KDPELGFFSHIVGNGCIMQVGPVDNGAWDVGGGWNAETYAAVELIESHSTKEEFMTDY
                     RLYIELLRNLADEAGLPKTLDTGSLAGIKTHEYCTNNQPNNHSDHVDPYPYLAKWGIS
                     REQFKHDIENGLTIETGWQKNDTGYWYVHSDGSYPKDKFEKINGTWYYFDSSGYMLAD
                     RWRKHTDGNWYWFDNSGEMATGWKKIADKWYYFNEEGAMKTGWVKYKDTWYYLDAKEG
                     AMVSNAFIQSADGTGWYYLKPDGTLADKPDFTVEPEGLITVK"
     gene            complement(5803..7155)
                     /locus_tag="VQ540_001936"
     CDS             complement(5803..7155)
                     /locus_tag="VQ540_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000364185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HET2545689.1"
                     /translation="MDLIHGPILPSLLSFTFPILLSNIFQQLYNTADVLIVGRFLGQE
                     SLAAVGATTAIFDLIVGFTLGVGNGMGIVIARYYGARNFTKIKEAVAATWILGALLSI
                     LVMLLGFLGLYHLLQYLDTPAEILPQSYQYISMIVTCVGVSFAYNLFAGLLRSIGDSL
                     AALGFLIFSALVNVVLDLYFITQLHLGVQSAGLATIISQGLSAVLCFYYIRKSVPELL
                     PQFKHFKWDKSLYADLLEQGLAMGLMSSIVSIGSVILQFSVNTFGAVIISAQTAARRI
                     MTFALLPMTAISASMTTFASQNLGAKRPDRIVQGLRIGSRLSISWAVFVCIFLFFASP
                     ALVSFLASSTDGYLIENGSLYLQISSAFYPILSLLLIYRNCLQGLGQKILPLVSSFIE
                     LIGKIVFVVLIIPWAGYKGVILCEPLIWVAMTVQLYFSLFRHPLIKEGKAILATKVQS
                     "
BASE COUNT         2298 a         1486 c         1132 g         2246 t
ORIGIN      
        1 tggtttcgca ggaagtctat tatatatgca cagacatatg aaatcttttt gagacagcag
       61 ttatgatata tttatccatt cacaacatct tctgtactaa tactacaata ttggtacatt
      121 ttgattacac aatcgtttca aaaaatatga tggaagcctg agtattttat agtaattccc
      181 ttcctatcaa ctagatcaac cagttgagtg ttgaatgttg aaacacccta gcctcagcaa
      241 aggactatga tcagcatttc ctagccaata ggacgctcca aatcacctat tctaagtcca
      301 tcactagctt ggtcagtaag atacagactg caaggcgaga ctgacgtggt tgatgagatt
      361 ttggaagagt attacaatca tagattcacc agtagacttg accgcagatt taactatagt
      421 agattgaaac tagaatagta catctctgct tctaaaacat tgttagaaat cgatttgact
      481 gtcctgatca atttgtcctg ttctcgtttc atttcactat actaaaaaac cacctgaaac
      541 aaatcaagtg actagaggat aaaaacaaag actaggcaaa aagttttgaa aagcaaaaaa
      601 cgcataatat caggtcttga aaaaccttga tactatacgt ttgattgtgg gaagattgac
      661 ttcattttct cctgaaattg aagttttttc tagtttccag atatagacga attcaatata
      721 gccatctcgc tacaattatt ttaaccatcg agaaaatttt tcagaatttc aaaaatttca
      781 ttttgatcca atgaaatgtc atcattttga agaatagttg acttcacagg ctctaattct
      841 atcacaaagc ggtgtatgtc tgcttttacc gcactacttg atgttatagc cgataacttt
      901 tcatctccta gcaaggaagc tgtcaaacgg gtaaggtcat tcaaatgctt tttaatggac
      961 ttacttaaac cttgagcacc tgtagcagag cgttccctca tatccagcca agctttagcc
     1021 ttaaaaataa ttaatactca atgaaaatca aagagcaaac taggaagcta gctgcaggct
     1081 gctcaaaaca ctgttttgag gttgtagatg gaagctgacg tggtttgaag agattttcga
     1141 agagtataaa ccacaattac tcaataccga atacccctga atggtttctt tttcatgcac
     1201 caatatatta taataatctt catccaataa taaggctgat aaactagcat cttggtcaaa
     1261 atgtaaggga atttctcgac cgtccttctt taatggatat tctggtaaga tactaaatag
     1321 ttcaatcata gaaggaaact caggattagt tgttgtaaat cgaaaaagct gcgctttctc
     1381 atctttctga cttccttgat actctcccaa ttctaaaaaa tgattcaagg tagtataaaa
     1441 ttccttattt tttacttcat aaatgatgac catatcataa tcttttgttg tgcgactttt
     1501 aaatccttgc gaatccaata cgatagaggt agcagttccc ccaatcagaa cataatagtt
     1561 ctgaaaatcc gcaaacattt cttgaaaaat aactttcgta ttagctggca tcatcttctc
     1621 ccagatactg taatatcata ttttctagtg cttcactctc ttcctctata cgtgggtcat
     1681 catcatcttt taaggtcaaa taaagagaaa tcggatctac aaattgttta tcatgattat
     1741 ttttaaaatc attccaaaac tcagatacaa aaggacgata tttccatatc tctagcatct
     1801 ttcattttaa aacatgctga gaaagtggca aggataactg attgaatttt ctctgccata
     1861 tgacatagct agtattttca tccgtttcag ctaaaaaagt tgaatgcgac aaagcataag
     1921 caccaccata tagaaggtta gaaacagatt ttatctgctt tatatcgcca tctggcaata
     1981 aaaaggcaat ccacgttaat tgttcgctag gtgttaattc cttagggatt tcagtatcat
     2041 tcgcattgag tactagtccc aatggaggga agaagaggtt tcccttaaag tctacaaacg
     2101 gaactctagc ttgaagtaat tgcttttttt cactgtctga taacttcgaa aacaccaaaa
     2161 caacatccat attggctttt tcacccatag tgcgagcctg agtaacaaat gaactcaaac
     2221 tcccccttct cttttcttta atcaataaaa atgattcctt atgaaaagtc atttgagtat
     2281 actcaaacct ttttacaaaa ctgattggta aagtcaaagt cagttcctca atactgacat
     2341 caacataaaa ggattgaaaa attgacatta tctttttgac attcatgttt tttccttatt
     2401 ctatcatttt tattatattt tatcattcgg tataataaaa tataagtttt ttgataaaat
     2461 aaccaaaaac tactcgctat cccctctcac attaccctac atatcgtttg acatgcgact
     2521 gatagttcag gaaaacttca aggagaactt ttctctcatc cactatgcag gacttactat
     2581 ttcacttcta ctcctatagg ctcaatttga cacttttctt tttcgaattg ctcatatgcc
     2641 tcctgaatag tgagttcgat ttatccaaat ttatttttgt ctattttgat gaatacttcc
     2701 acgaagatag tctgaaaatg aatttgcacc aattttcctt ctctttttaa gcatattatt
     2761 ccagatatga ttgccctctt gttcagtaat aaattacgct ttaaacgctt caatcagtat
     2821 atctcctgtt gtcatatgtt ctaaagaaaa ttcttctaca tatggtttaa catctcttag
     2881 gttattactt cctaatatcc cattatgctt tttcgctaag aaaatagaag tcgcttctcc
     2941 cttaccaata atcttgttac tatcataatt tcttgttaaa tctctatata atgcgtattc
     3001 ttcagttcca atgtctatgc tcacaatctc agctgaaccc ttagttacca actggtctat
     3061 cctagatttt aaatggggaa ttgtaggtat attgatttca tcatacacct cttgtggaat
     3121 aacaatttta cccgaataga gcttttctaa aagatgttca gtgccaaccc ataaaaatgc
     3181 tgaaatacaa tctgcatcaa taaatacacg actagtcaaa cgacaactcc ccctcttcat
     3241 ctagcccata tacaatatca tatctgaaag catctagtaa cagttcctca tacttccctt
     3301 gcgaaattct gttattttct aaaagttgtt cagtcgattt aatatagtgc cctaatacca
     3361 tttccttttt actttctgac aaaggacgat ataaacttgt atcatagcct aatcttgaag
     3421 ctgtctctat aacactaata tccatatttt taatttcttc tgcatcaagg tatccatcat
     3481 ttctcaatct atataacata gctttatgac tgataccata aaactgaccc aattttataa
     3541 tatcttctac ttcaagatga gttctattgg cattttctct gatttcctca accatcctat
     3601 acagtgaaga tgggaaaatt aaaaaataag aagcaaactg atccgctttt ctttcagttt
     3661 catctccttc accaatcaag ataagactga ctgaactctt cttcacctca tcataataaa
     3721 gatgatacag tccatgtgct aaagaaaatc tttaccttcc taatggcatg tctgaattga
     3781 ctgcaatgag actgaactga gttcctttat aacagactcc gctaatattc tttccgagtc
     3841 cataaaatac cagcgtcaaa ttttctatct tttgtaccaa tttaaaaata tctatcggcg
     3901 attcaccatc agctcccaac ttttttctaa gatttgaagc tttattactt aaatccattc
     3961 gtgatattcc tttcaccttt ttccattttg gcaatcatgc tttgattcaa agacaaatac
     4021 tcagcaatct tatcttgagt aagatttgaa gatattctaa gttcttttat tctttttcca
     4081 acatcacata catttatcat attcatacac ctctcataaa aagaatagca cattcttgtc
     4141 ataatttttt aaataaaaaa attatgacaa aacaaggaag caatttattg atgctactta
     4201 aaaatctaaa attgatgata ttaaacctat ttgatgagtt cctatcaaaa atcgtatctt
     4261 caacctcaaa acagtactta aagctatccg actcggttta cattgtcaaa tttagatttt
     4321 atttgagcat aactttctag tttgcttttt gatttttgtt taatatagta acaaaaattg
     4381 aaggaaatat ctccacaaga aaacgcatac tattaagctt tttcaagacc taataatatg
     4441 cgctgttctg atttgaaaga cattccatta ttattttact gtaatcaagc cttcaggctc
     4501 tactgtgaag tctggcttgt ctgccagtgt tccgtctggt ttgaggtagt accagcctgt
     4561 tccgtccgct gactggataa aggcatttga taccatggcg ccttctttag cgtctaagta
     4621 gtaccaagtg tccttgtact tgacccagcc tgtcttcatg gcaccttctt cgttgaaata
     4681 gtaccactta tcagcgattt tcttccagcc tgtagccatt tcgcctgagt tgtcgaacca
     4741 gtaccagttg ccgtctgtgt gcttcctcca gcggtctgca agcatatagc ctgaactgtc
     4801 aaagtagtac caagtgccat tgattttctc aaacttgtct tttggataag agccgtctga
     4861 atgtacgtac cagtagccag tgtcattctt ctgccagcct gtttcaatcg tcaagccgtt
     4921 ctcaatatca tgcttaaact gctcacggct aatgccccat ttagcaagat atggataagg
     4981 gtcaacgtgg tctgagtggt tgtttggttg gttattcgtg caatactcgt gcgttttaat
     5041 tccagctaaa ctccctgtat caagcgtttt cggcaaacct gcttcatctg ctagattgcg
     5101 taagagttcg atataaaggc ggtagtccgt catgaactct tctttggttg aatggctttc
     5161 aatcagttca accgctgcat aggtctcagc attccaaccg cccccaacgt cccaggcacc
     5221 attatcaaca ggtcctacct gcatgatgca accgttccca acaatgtgcg agaaaaaacc
     5281 taattctggg tctttccgcc agtgataatc cgcttcattc tgtacggttg aatgcggatt
     5341 cccagttgag tgtgcgtgta cttgcctata tggttgcacg ccgacttgag gcaaatctgt
     5401 tcttaattta ctcacattaa tttccatatt ctactcctta tcaattaaaa caactcattt
     5461 tttacaatcc agaaccagaa actcctttat ttctacctta caaagaagac aatcttagtc
     5521 acgattaagc ttgtagatag aacctcaaaa cgcactattt tgacactgta aataggactg
     5581 acaaggtctg cattctatct acaataacac cccagactaa aaagcttttc aaaagtatat
     5641 ttttacagtc tctatatgtc cttttcataa atactatact ttattatatc acataaaaga
     5701 agtcaaaagt ctgttaaact attttcaaca ccaaactaaa gaagagaaca caagtttttt
     5761 cgatgttcac tagaggaaat ggattttatt cagtaaatcc aactaggatt gcactttggt
     5821 tgccaaaatt gcctttcctt cttttatcaa gggatgacgg aatagtgaga agtacagttg
     5881 aactgtcatg gcaacccaga taagaggttc acaaaggata acacccttat atcctgccca
     5941 aggaataatc aaaaccacaa aaacgatttt tccgattagt tcaataaagc tagaaactag
     6001 aggaaggatc ttctgcccca agccctgcaa gcaattgcga taaatcaaca agaggctcaa
     6061 aatgggataa aaggctgaac tgatttgcag atagagactt ccattttcta tcaagtaacc
     6121 atctgtcgaa ctagccaaga aggaaaccaa ggctggactg gcaaaaaaga ggaaaataca
     6181 aacaaaaact gcccaggata tacttaaacg actgccgatt cgaagacctt gaacaatgcg
     6241 gtcaggtcgc ttagctccta gattctgaga agcaaaggtc gtcattgatg cagaaatagc
     6301 ggtcatagga agaagggcaa aggtcataat gcgtcgagct gccgtctggg cactaataat
     6361 cactgcacca aatgtattaa cagaaaactg taaaatcaca ctgccgatag atacaattga
     6421 actcatcaag cccatagcca aaccttgctc caagagatcc gcgtacaagc ttttgtccca
     6481 tttgaaatgt ttaaactgtg gcaagagttc tggcacactt ttacgaatat aataaaagca
     6541 gagaaccgct gataaacctt gcgaaataat ggtagcaagt cctgcggatt gaactcccag
     6601 atgcaattgc gtaataaaat agagatccag aaccacatta accaaggcag agaaaatcag
     6661 aaatcccagg gctgctagac tgtcaccaat agaccgcaac aagcctgcaa aaagattata
     6721 agcaaagctg acacctacac aggtcacaat catagaaata tattgataag attgaggaag
     6781 aatttctgca ggagtatcta agtattgcaa gagatgatac aagccaagaa agcccagcaa
     6841 cataactaga atgctcaaaa gagcacctaa aatccaagta gctgctactg cttccttgat
     6901 tttagtgaaa ttccgagccc cataataacg agcaatgaca atccccatgc cattgccaac
     6961 accaagtgta aaacctacaa tcaggtcaaa aatcgctgtc gtcgctccta ctgcagccaa
     7021 ggattcttga ccaagaaatc gtccaacaat caagacatca gcagtgttat agagctgttg
     7081 aaaaatattt gatagcaaaa ttggaaaggt gaagcttaag agcgagggaa gaatcggacc
     7141 atgtatcagg tccactgttc gt
//
LOCUS       DAVBDR010000077         7107 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.077, whole genome shotgun sequence.
ACCESSION   DAVBDR010000077 DAVBDR010000000
VERSION     DAVBDR010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7107)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7107)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7107
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.077"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            complement(394..2085)
                     /locus_tag="VQ540_001937"
     CDS             complement(394..2085)
                     /locus_tag="VQ540_001937"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HET2545690.1"
                     /translation="MNTKELIASELASIIDSLDQEAILKLLETPKNSEMGDIAFPAFS
                     LAKVERKAPQMIAAELAEKMNSQAFEKVVATGPYVNFFLDKSAISAQVLQAVTTEKEH
                     YADQNIGKQENVVIDMSSPNIAKPFSIGHLRSTVIGDSLSHIFQKIGYQTVKVNHLGD
                     WGKQFGMLIVAYKKWGDEEAVKAHPIDELLKLYVRINAEAENDPSLDEEAREWFRKLE
                     NGDEEALALWQWFRDESLVEFNRLYNELKVEFDSYNGEAFYNDKMDAVVDILSEKGLL
                     LESEGAQVVNLEKYGIEHPALIKKSDGATLYITRDLAAALYRKNEYQFAKSIYVVGQE
                     QSAHFKQLKAVLQEMGYDWSDDITHVPFGLVTKEGKKLSTRKGNVILLEPTVAEAVSR
                     AKVQIEAKNPELENKDQVAHAVGVGAIKFYDLKTDRTNGYDFDLEAMVSFEGETGPYV
                     QYAYARIQSILRKADFKPETAGNYSLNDTESWEIIKLIQDFPRIINRAADNFEPSIIA
                     KFAISLAQSFNKYYAHTRILDESPERDSRLALSYATAVVLKEALRLLGVEAPEKM"
     gene            2221..2667
                     /gene="argR"
                     /locus_tag="VQ540_001938"
     CDS             2221..2667
                     /gene="argR"
                     /locus_tag="VQ540_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HET2545691.1"
                     /translation="MRKRDRHQLIKKMITEEKLSTQKEIQDRLEAHNVCVTQTTLSRD
                     LREIGLTKVKKNDMVYYVLVNETEKIDLVEFLSHHLEGVARAEFTLVLHTKLGEASVL
                     ANIVDVNKDEWILGTVAGANTLLVICRDQHVAKLMEDRLLDLMKDK"
     gene            2718..5252
                     /gene="mutS"
                     /locus_tag="VQ540_001939"
     CDS             2718..5252
                     /gene="mutS"
                     /locus_tag="VQ540_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HET2545692.1"
                     /translation="MAIEKLSPGMQQYVDIKKQYPDAFLLFRMGDFYELFYEDAVNAA
                     QILEISLTSRNKNADNPIPMAGVPYHSAQQYIDVLIEQGYKVAIAEQMEDPKQAVGVV
                     KREVVQVITPGTVVDSSKLDSQNNFLVAIDREGNQFGLAYMDLVTGDFYVTGLLDFTL
                     VCGEIRNLKAREVVLGYDLSEEEEQILSCQMNLVLSYEKESFEDLHLLDLRLATVEQT
                     ASSKLLQYVHRTQMRELNHLKPVIRYEIKDFLQMDYATKASLDLVENARSGKKQGSLF
                     WLLDETKTAMGMRLLRSWIHRPLIDKERIVQRQEVVQVFLDHFFERSDLTDSLKGVYD
                     IERLASRVSFGKTNPKDLLQLATTLSSVPRIRAILEGMEQPALAYLIAQLDAIPELES
                     LISAAIAPEAPHVITDGGIIRTGFDETLDKYRCVLREGTSWIAEIEAKERENSGISTL
                     KIDYNKKDGYYFHVTNSQLGNVPAHFFRKATLKNSERFGTEELARIEGDMLEAREKSA
                     NLEYEIFMRIREEVGKYIQRLQALAQGIATVDVLQSLAVVAETQHLIRPEFGDDSQID
                     IRKGRHAVVEKVMGAQTYIPNTIQMAEDTSIQLITGPNMSGKSTYMRQLAMTAVMAQL
                     GSYVPAESAHLPIFDAIFTRIGAADDLVSGQSTFMVEMMEANNAISHATKNSLILFDE
                     LGRGTATYDGMALAQSIIEYIHEHIGAKTLFATHYHELTSLESSLQHLVNVHVATLEQ
                     DGQVTFLHKIEPGPADKSYGIHVAKIAGLPADLLARADKILTQLENQGTENPPPMRQT
                     SAVTEQISLFDRAEEHPILAELAKLDVYNMTPMQVMNVLVELKQKL"
     gene            5399..7093
                     /gene="patA"
                     /locus_tag="VQ540_001940"
     CDS             5399..7093
                     /gene="patA"
                     /locus_tag="VQ540_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatA"
                     /protein_id="HET2545693.1"
                     /translation="MLIQKIKTYKWQALASLLMTGLMVASSLLQPRYLQEVLGALLTG
                     KYEAIYSIGAWLIGVAVVGLVAGGLNVVLAAYIAQGVSSDLREDAFRKIQTFSYADIE
                     QFNAGNLVVRMTNDINQIQNVVMMTFQILFRLPLLFIGSFILAVQTLPSLWWVIVLMV
                     VLIFGLTAVMMGMMGPRFAKFQTLLERINAIAKENLRGVRVVKSFVQEKEQFAKFTEV
                     SDELLGQNLYIGYAFSVVEPFMMLVGYGAVFLSIWLVAGMVQSDPSVVGSIASFVNYL
                     SQIIFTIVMVGFLGNSVSRAMISMRRIREILDAEPAMTFKDVPDEELVGSLSFENVTF
                     TYPMDKEPMLKDVSFTIEPGQMVGVVGATGAGKSTLAQLIPRLFDPQEGAIKIGGKDI
                     REVSEGTLRKTVSIVLQRAILFSGTIADNLRQGKGNATLFEMERAANIAQASEFIHRM
                     EKTFESPVEERGTNFSGGQKQRMSIARGIVSNPRILIFDDSTSALDAKSERLVQEALN
                     KDLKGTTTIIIAQKISSVVHADKILVLNQGRLIGQGTHADLVANNAVYREIYETQK"
BASE COUNT         1933 a         1383 c         1685 g         2106 t
ORIGIN      
        1 cttcggatta cgaatgaatt tgattgctgg cattatcaat catgaactag gattctagtt
       61 ttgcaggaag tctattattt ggttaggtga attagtgaag cgtttaggca agtgtctctg
      121 gttacgacgt catggactct aaatcgatta tatttagggg tcatgactag tgaagcagtt
      181 agctagttcg catataagcg gctagcgtct aacaattagg aactttagtt ccaataactt
      241 taagattacg acgttttagg acataaatcg atcatattta tgtcctaaaa ctagtgaagt
      301 atgtcctaaa actagtgaag cgcctagcca aagtccgaat aggatttggc gttagttact
      361 tagattgctt tgcaatcaag taactttggc gatttacatc ttctctggcg cttctactcc
      421 aagcaagcga agggcttctt tgagaacgac tgcggttgcg tagctgaggg ctagacggct
      481 gtcgcgttct gggctttcat ccaagatacg tgtatgtgca tagtatttgt taaaggattg
      541 agccaggcta attgcaaatt tagcaatgat agaaggttca aagttatctg ccgcacggtt
      601 gataatacgt gggaagtctt gaatgagttt aatgatttcc cagctttcag tatcattcaa
      661 gctatagttg ccagctgttt ctggtttgaa atcggctttg cgtaagatag attggatacg
      721 agcgtaggca tattgaacgt aaggtccagt ttcaccctcg aaggatacca tagcctctag
      781 gtcgaagtcg tatccatttg tacggtcggt tttgaggtca tagaatttaa tggctccaac
      841 cccaacagca tgtgctactt ggtctttgtt ttctagttca ggatttttag cctcgatttg
      901 gaccttggca cggctaacag cctctgcaac agtaggctct agcaagatga cattcccttt
      961 acgagtagag agtttcttcc cttcttttgt aaccaaacca aaaggaacgt gagtaatgtc
     1021 gtcactccag tcgtagccca tctcttgcaa gacagctttg agctgtttaa agtgggcaga
     1081 ttgttcttga ccaacgacat agatagattt agcaaattgg tattcgtttt tacggtagag
     1141 ggctgcagcc aagtcacgtg tgatatagag agttgcacca tcagacttct tgatgagggc
     1201 tggatgttca attccgtatt tctcaagatt cacaacttgg gcaccttctg attcaagaag
     1261 tagtcctttt tcagaaagaa tgtctacaac tgcatccatc ttatcattgt agaaggcttc
     1321 tccgttatag ctgtcaaatt caaccttcaa ttcattgtaa aggcggttaa attccactaa
     1381 actttcatcg cggaaccatt gccaaagagc gagagcttcc tcatctccat tttcaagttt
     1441 acggaaccat tcgcgcgctt cttcatccaa gctagggtca ttttcagctt cagcgttgat
     1501 gcggacatag agtttaagga gttcatcgat tggatgagct tttacagctt cttcgtcgcc
     1561 ccattttttg taggcaacaa tcaacatccc aaattgttta ccccagtctc ccaaatggtt
     1621 gaccttgacc gtttgataac cgattttttg gaaaatatgt gacaagctat ctccgataac
     1681 agttgaacgc aggtggccaa tagaaaatgg tttagcgata ttcggactag acatgtcgat
     1741 aacaacattt tcttgtttac caatattttg gtcagcatag tgttcttttt cagtggtaac
     1801 agcttgcaat acttgagcag aaatggcaga tttatcaagg aaaaagttaa cgtaaggtcc
     1861 tgttgcgaca actttttcaa aggcttggct gttcattttt tcagccagtt cagccgcaat
     1921 catttgtggt gctttacgtt cgactttggc aagagaaaaa gcagggaaag cgatgtcacc
     1981 catttctgag tttttagggg tttccagtaa ctttaaaata gcctcttggt ccaggctatc
     2041 aatgatgcta gccaattcgc tagcaatcaa ttcttttgta ttcattaaga gctccttttt
     2101 ggacttttct actattttat cacaatttta aagaaagaag aaaaaatttt tgaaatctcc
     2161 tgtttttttg gtataatatg gttataaata tagttataaa tatgcacgca agaggatttt
     2221 atgagaaaaa gagatcgtca tcagttaata aaaaaaatga ttactgagga gaaattaagt
     2281 acacaaaaag aaattcaaga tcggttggag gcgcacaatg tttgtgtgac gcagacaacc
     2341 ttgtctcgtg atttgcgcga aatcggcttg accaaggtca agaaaaatga tatggtgtat
     2401 tatgtactag taaatgagac agaaaagatt gatttggtgg aatttttgtc tcatcattta
     2461 gaaggtgttg caagagcaga gtttaccttg gtgcttcata ccaaattggg agaagcctct
     2521 gttttggcaa atattgtaga tgtaaataag gatgaatgga ttttaggaac agttgctggt
     2581 gccaatacct tattggttat ttgtcgagat cagcacgttg ccaaactcat ggaagatcgt
     2641 ttgctagatt tgatgaaaga taagtaaggt cttgggagtt gctctcaaga cttatttttg
     2701 aaaaggagag acagaaaatg gcgatagaaa agctatcacc cggcatgcaa cagtatgtgg
     2761 atattaaaaa gcaatatcca gatgcttttt tgctctttcg gatgggtgat ttttatgaat
     2821 tattttatga ggatgcggtc aatgctgcgc agattctgga aatttcctta acgagtcgca
     2881 acaagaatgc cgacaatccg atccctatgg cgggtgttcc ctatcattct gcccaacagt
     2941 atatcgatgt cttgattgag cagggttata aggtggctat cgcagagcag atggaagatc
     3001 ctaaacaagc agttggggtt gttaaacgag aggttgttca ggtcattacg ccagggacag
     3061 tggtcgatag cagtaagctg gacagtcaga ataatttttt ggttgccata gaccgcgaag
     3121 gcaatcaatt tggcctagct tatatggatt tggtgacggg tgacttttat gtgacaggtc
     3181 ttttggattt cacgctggtt tgtggggaaa tccgtaacct caaggctcga gaagtggtgt
     3241 tgggttatga cttgtctgag gaagaagaac aaatcctcag ctgccagatg aatctggtac
     3301 tctcttatga aaaagaaagc tttgaagacc ttcatttatt ggatttgcga ttggcaacgg
     3361 tggagcaaac ggcatctagt aagctgctcc agtatgttca tcggactcag atgagggaat
     3421 tgaaccacct caaacctgtt atccgctacg aaattaagga tttcttgcag atggattatg
     3481 cgaccaaggc tagtctggat ttggttgaga atgctcgctc aggtaagaaa caaggcagtc
     3541 ttttctggct tttggatgaa accaaaacgg ctatggggat gcgtctcttg cgttcttgga
     3601 ttcatcgccc cttgattgat aaggaacgaa tcgtccaacg tcaagaagta gtgcaggtct
     3661 ttctcgacca tttctttgag cgtagtgact tgacagacag tctcaagggt gtttatgaca
     3721 ttgagcgctt ggctagtcgt gtttcttttg gcaaaaccaa tccaaaggat ctcttgcagt
     3781 tggcgactac cttgtctagt gtgccacgga ttcgtgcgat tttagaaggg atggagcaac
     3841 ctgctctagc ctatctcatc gcacaactgg atgcaatccc tgagttggag agtttgatta
     3901 gcgcagcgat tgctcctgaa gctcctcatg tgattacaga tgggggaatt atccggactg
     3961 gatttgatga gactttagac aagtatcgtt gcgttctcag agaagggact agctggattg
     4021 ctgagattga ggctaaggag cgagaaaact ctggtatcag cacgctcaag attgactaca
     4081 ataaaaagga tggctactat tttcatgtga ccaattcgca actgggaaat gtgccagccc
     4141 actttttccg caaggcgacg ctgaaaaact cagaacgctt tggaaccgaa gaattagccc
     4201 gtatcgaggg agatatgctt gaggcgcgtg agaagtcagc caacctcgaa tacgaaatat
     4261 ttatgcgcat tcgtgaagag gtcggcaagt acatccagcg tttacaagct ttagcccaag
     4321 gaattgcgac ggttgatgtc ttacagagtc tggcggttgt ggctgaaacc cagcatttga
     4381 ttcgacctga gtttggtgac gattcacaaa ttgatatccg gaaagggcgc catgctgtcg
     4441 ttgaaaaggt tatgggggct cagacctata ttccaaatac gattcagatg gcagaagata
     4501 ccagtattca actgattaca gggccaaaca tgagtgggaa gtctacctat atgcgtcagt
     4561 tagccatgac ggcggttatg gcccagctgg gttcctatgt tcctgctgaa agcgcccatt
     4621 taccgatttt tgatgcgatt tttacccgta tcggagcagc agatgacttg gtttcgggtc
     4681 agtcaacctt tatggtggag atgatggagg ccaataatgc catttcgcat gcgaccaaga
     4741 actctctcat tctctttgat gaattgggac gtggaactgc aacttatgac gggatggctc
     4801 ttgctcagtc catcatcgaa tatatccatg agcacatcgg agctaagacc ctctttgcga
     4861 cccactacca tgagttgact agtctggagt ctagtttaca acacttggtc aatgtccacg
     4921 tggcaacttt ggagcaggat gggcaggtca ccttccttca caagattgaa ccgggaccag
     4981 ctgataaatc ctacggtatc catgttgcca agattgctgg cttgccagca gaccttttag
     5041 caagggcgga taagattttg actcagctag agaatcaagg aacagagaat cctcctccca
     5101 tgagacaaac tagtgctgtc actgaacaga tttcactctt tgatagggca gaagagcatc
     5161 ctatcctagc agaattagct aaactggatg tgtataatat gacacctatg caggttatga
     5221 atgtcttagt agagttaaaa cagaaactat aaaaccaaga ctcactagtt aatctagctg
     5281 tagcaaggag acttctttga caattctcca cttttttgct agaatgacat cacacaaaca
     5341 gaatgaaaag gagctgacgc attgtcgctc ccttttgtct attttttaag gagaaagtat
     5401 gctgattcag aaaataaaaa cctacaagtg gcaggccctg gcttcgctcc tgatgacagg
     5461 cttgatggtt gctagttcac ttctgcaacc gcgttatctg caggaagtct taggcgccct
     5521 ccttactggg aaatatgaag ctatttatag tatcggggct tggttgattg gtgtggccgt
     5581 agtcggtcta gttgctggtg gactcaatgt tgtcctcgca gcctatattg cccaaggagt
     5641 ttcatccgac cttcgggagg atgccttccg taaaattcaa accttttctt atgctgatat
     5701 tgaacaattt aatgcgggaa atctagtcgt tcgaatgaca aatgatatca accagattca
     5761 gaacgttgtc atgatgacct tccagattct tttcagactt cccctcttgt tcatcggttc
     5821 gtttatccta gcggttcaaa ccttaccttc tctgtggtgg gtgattgttc tcatggtagt
     5881 cttgattttt ggtttgactg ctgtcatgat gggaatgatg gggcctcgtt ttgccaagtt
     5941 tcaaaccctt cttgagcgca tcaatgccat tgccaaggaa aatttacgtg gcgttcgtgt
     6001 ggtcaagtcc tttgtccaag aaaaagagca atttgctaag tttacagagg tctcagacga
     6061 gcttcttggt caaaaccttt acattggtta tgccttttca gtagtggaac cctttatgat
     6121 gttggttggt tacggggcgg tcttcctctc tatttggctg gtcgcgggaa tggttcagtc
     6181 ggatccgtct gttgttggtt ccatcgcttc ttttgttaat tacctaagcc agattatctt
     6241 taccattgtt atggttggat ttttgggaaa ttctgtcagc cgtgccatga tttccatgcg
     6301 tcgtattcga gaaattcttg acgcagagcc agctatgacc ttcaaggatg tcccagatga
     6361 agagttggtt ggaagcctta gctttgaaaa tgtgaccttt acctatccaa tggacaagga
     6421 accgatgctg aaagatgtga gctttactat tgaacctggt caaatggttg gtgtagttgg
     6481 agcgactggt gcaggaaagt caaccttggc tcaattgatt ccacgtctct ttgatccaca
     6541 ggaaggggct atcaaaatcg gaggtaagga tattcgagaa gtgagtgaag gaaccctgcg
     6601 taaaacagtt tccatcgttc tccaacgtgc cattcttttt agtggaacga ttgcagataa
     6661 cttgagacag gggaagggaa atgctactct atttgaaatg gagcgcgcag ccaatattgc
     6721 ccaggctagt gaattcattc atcgtatgga gaaaaccttt gaaagtccag ttgaagaacg
     6781 gggaaccaat ttctctggtg gacaaaaaca aaggatgtcg attgcgcgtg ggattgtcag
     6841 caatccacgt attctgattt ttgatgattc gacctcagcc ttggatgcca aatcagagcg
     6901 cttggtgcaa gaagctttga ataaggactt gaaggggacg acaaccatta ttattgctca
     6961 aaaaattagc tcggttgtcc atgcagacaa gatcttggtt ctaaatcaag gacgattgat
     7021 tggtcaaggc acgcatgcag acttggttgc caacaatgcc gtttaccgtg aaatctatga
     7081 aacacagaaa tgaaagacaa actataa
//
LOCUS       DAVBDR010000078         7031 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.078, whole genome shotgun sequence.
ACCESSION   DAVBDR010000078 DAVBDR010000000
VERSION     DAVBDR010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7031)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7031)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7031
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.078"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            226..6657
                     /locus_tag="VQ540_001941"
     CDS             226..6657
                     /locus_tag="VQ540_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HET2545694.1"
                     /translation="MKKSTVLSLTTAAVILAAYAPNEVVLADTSSSEDALNISDKEKV
                     VVDKETENKEKHEDIHNAIETSQDFKEKKTAVIEGKEVVSKNPVTDNNTSNEEARIKE
                     DSNQSQGDHTDSFVNKNTENPKKEDKVVYIAEFKDKESGEKAIKQLSNLKNTKVLYTY
                     DRIFNGSAIETTPDNLDKIKQIEGISSVERAQKVQPMMNHARKEIGVEEAIDYLKSIN
                     APFGKNFDGRGMVISNIDTGTDYRHKAMRIDDDAKASMRFKKEDLKGTDKNYWLSDKI
                     PHAFNYYNGGKITVEKYDDGRDYFDPHGMHIAGILAGNDTEQDIKNFNGIDGIAPNAQ
                     IFSYKMYSDAGSGFAGDETMFHAIEDSIKHNVDVVSVSSGFTGTGLVGEKYWQAIRAL
                     RKAGIPMVVATGNYATSASSSSWDLVANNHLKMTDTGNVTRTAAHEDAIAVASAKNQT
                     VEFDKVNIGGESFKYRNIGAFFDKNKITTNEDGTKAPSKLKFVYIGKGQDQDLIGLDL
                     RGKIAVMDRIYTKDLKNAFKKAMDKGARAIMVVNTVNYYNRDNWTELPAMGYEADEGT
                     KSQVFSISGDDGVKLWNMINPNKKTEVKRNNKEDFKDKLEQYYPIDMESFNSNKPNVG
                     DEKEIDFKFAPDTDKELYKEDIIVPAGSTSWGPRIDLLLKPDVSAPGKNIKSTLNVIN
                     GKSTYGYMSGTSMATPIVAASTVLIRPKLKEMLERPVLKNLKGDDKIDLTSLTKIALQ
                     NTARPMMDATSWKEKSQYFASPRQQGAGLINVANALRNEVVATFKNTDSKGLVNSYGS
                     ISLKEIKGDKKYFTIKLHNTSNRPLTFKVSASAITTDSLTDRLKLDETYKDEKSPYGK
                     QIVPEIHPEKVKGANITFEHDTFTIGANSSFDLNAVINVGEAKNKNKFVESFIHFESV
                     EEMEALNSNGKKINFQPSLSMPLMGFAGNWNHEPILDKWAWEEGSRSKTLGGYDDDGK
                     PKIPGTLNKGIGGEHGIDKFNPAGVIQNRKDKNTTSLDQNPELFAFNNQGINAPSSSG
                     SKIANIYPLDSNGNPQDAQLERGLTPSPLVLRSAEEGLISIVNTNKEGENQRDLKVIS
                     REHFIRGILNSKSNDAKGIKSSKLKVWGDLKWDGLIYNPRGREENAPESKDNQDPATK
                     IRGQFEPIAEGQYFYKFKYRLTKDYPWQVSYIPVKIDNTAPKIVSVDFSNPEKIKLIT
                     KDTYHKVKDQYKNETLFARDQKEHPEKFDEIANEVWYAGAALVNEDGEVEKNLEVTYA
                     GEGQGRNRKLDKDGNTIYEIKGAGDLRGKIIEVIALDGSSNFTKIHRIKFANHADEKG
                     MISYYLVDPDKDASKYEKLGEISEDKLKNAKSPEENTNNNQAKDEDSKPDEKSSVEGE
                     ASLEINKTISTIREFENKDLKKLIKKKFREVDDFTSETGKRIEEYDYKYDDKGNIIAY
                     DDGSALQYETEKLDEIKSKIYGVLSPSKDGHFEILGKISNVSKNAKVYYGNSYKSIEI
                     KATKYDSHSKTMIFDLYANINDIVDGLAFAGDMRLFVKDDNQIKAETKIRMPEKNKET
                     KAEYPYVSSYGNVIELGEGDLSKNKPDNLTKMESGKIYSDSEKQQYLLKDNIILRKGY
                     ALKVTTYNPGKTDMLEGNGVYSKEDIAKIQKANPNLRVLSETTIYADSRNVEDGRSTQ
                     AVLMSALDGFNIIRYQVFTFKMNDKGEAIDKDGNLVTDSSKLVLFGKDDKEYTGEDKS
                     NVEAIKEDGSMLFIDTKPVNLSMDKNYFNPSKSNKIYVRNPEFYLRGKISDKGGFNWE
                     LRVNESVVDNYLIYGDLHIDNTRDFNIKLNVKDGDIMDWGMKDYKANGFPDKVTDMDG
                     NVYLQTGYSDLNAKAVGVHYQFLYDNVKPEVNIDPKGNTSIEYADGKSVVFNINDKRN
                     NGFDGEIQEQHIYVNGKEYTSFDDIKQITDKTLNIKIVVKDFARNTTVKEFILNKDTG
                     EVSELKPHRVTVTIQNGKEMSSTIVSEEDFILPVYKGELEKGYQFDGWEISGFEGKKD
                     AGYVINLSKDTFIKPVFKKIEEKKEEENKPTFDVSKKKDNPQVNHSQLNESHRKEDLQ
                     REDHSQKSDSTKDVTATVLDKNNISSKSTTNNPNKLPKTGTASGAQTLLAAGIMFIVG
                     IFLGLKKKNQD"
BASE COUNT         2772 a          948 c         1356 g         1955 t
ORIGIN      
        1 taatcttatt ttttaacgtg tgctaaaaaa taaattaatg catgttaatt tttcttgaat
       61 taaatttttt taaatgatat actgttttta tggagagata acaattatat ataaatgtac
      121 tactctattt cctagataat acttagtaaa actttttata acaaaggcta gcaaagttaa
      181 agtttattat ctattggaag ttaaataaat atgtaaggaa ttaaaatgaa aaaaagtaca
      241 gtattgtcat taaccacagc tgcagttatt ttagcagcct atgcccctaa tgaggtagtc
      301 ttagcagaca catctagctc tgaagatgct ttaaacatct ctgataaaga aaaagtagta
      361 gtagataagg aaacagaaaa taaagagaaa catgaagata ttcataatgc tatagaaact
      421 tcacaggatt ttaaagagaa gaaaacagca gtcattgagg gaaaagaagt tgttagtaaa
      481 aatcctgtga cagacaataa cactagcaat gaagaagcaa gaatcaaaga agattccaat
      541 caatcccaag gagatcatac ggactcattt gtgaataaaa acacagaaaa tcccaaaaaa
      601 gaagataaag ttgtctatat tgctgaattt aaagataaag aatctggaga aaaagcaatc
      661 aagcaactat ccaatcttaa gaatacaaaa gttttatata cttatgatag aatttttaac
      721 ggtagtgcca tagaaacaac tccagataac ttggacaaaa ttaaacaaat agaaggtatt
      781 tcatcggttg aaagggcaca aaaagtccaa cccatgatga atcatgccag aaaggaaatt
      841 ggagttgagg aagctattga ttacctaaag tctatcaatg ctccgtttgg gaaaaatttt
      901 gatggtagag gtatggtcat ttcaaatatc gatactggaa cagattatag acataaggct
      961 atgagaatcg atgatgatgc caaagcctca atgagattta aaaaagaaga cttaaaagga
     1021 actgataaaa attattggtt gagtgataaa atccctcatg cgttcaatta ttataatggt
     1081 ggcaaaatca ctgtagaaaa atatgatgat ggaagggatt attttgaccc acatgggatg
     1141 catattgcag ggattcttgc tggaaatgat actgaacaag atatcaaaaa ctttaacggc
     1201 atagatggaa ttgcacctaa tgcacaaatt ttctcttaca aaatgtattc tgacgcagga
     1261 tctgggtttg cgggtgatga aacaatgttt catgctattg aagattctat caaacacaac
     1321 gttgatgttg tttcggtatc atctggtttt acaggaacag gtcttgtagg tgagaaatat
     1381 tggcaagcta ttcgggcatt aagaaaagca ggcattccaa tggttgtcgc tacgggtaac
     1441 tatgcgactt ctgcttcaag ttcttcatgg gatttagtag caaataatca tctgaaaatg
     1501 accgacactg gaaatgtaac acgaactgca gcacatgaag atgcgatagc ggtcgcttct
     1561 gctaaaaatc aaacagttga gtttgataaa gttaacatag gtggagaaag ttttaaatac
     1621 agaaatatag gggccttttt cgataagaat aaaatcacaa caaatgaaga tggaacaaaa
     1681 gctcctagta aattaaaatt tgtatatata ggcaaggggc aagaccaaga tttgataggt
     1741 ttggatctta ggggcaaaat tgcagtaatg gatagaattt atacaaagga tttaaaaaat
     1801 gcttttaaaa aagctatgga taagggtgca cgcgccatta tggttgtaaa tactgtaaat
     1861 tactacaata gagataattg gacagagctt ccagctatgg gatatgaagc ggatgaaggt
     1921 actaaaagtc aagtgttttc aatttcagga gatgatggtg taaagctatg gaacatgatt
     1981 aatcctaata aaaaaactga agtcaaaaga aataataaag aagattttaa agataaattg
     2041 gagcaatact atccaattga tatggaaagt tttaattcca acaaaccgaa tgtaggtgac
     2101 gaaaaagaga ttgactttaa gtttgcacct gacacagaca aagaactcta taaagaagat
     2161 atcatcgttc cagcaggatc tacatcttgg gggccaagaa tagatttact tttaaaaccc
     2221 gatgtttcag cacctggtaa aaatattaaa tccacgctta atgttattaa tggcaaatca
     2281 acttatggct atatgtcagg aactagtatg gcgactccaa tcgtggcagc ttctactgtt
     2341 ttgattagac cgaaattaaa ggaaatgctt gaaagacctg tattgaaaaa tcttaaggga
     2401 gatgacaaaa tagatcttac aagtcttaca aaaattgccc tacaaaatac tgcgcgacct
     2461 atgatggatg caacttcttg gaaagaaaaa agtcaatact ttgcatcacc tagacaacag
     2521 ggagcaggcc taattaatgt ggccaatgct ttgagaaatg aagttgtagc aactttcaaa
     2581 aacacggatt ctaaaggttt ggtaaactca tatggttcca tttctcttaa agaaataaaa
     2641 ggtgataaaa aatactttac aatcaagctt cacaatacat caaacagacc tttgactttt
     2701 aaagtttcag catcagcgat aactacagat tctctaactg acagattaaa acttgatgaa
     2761 acatataaag atgaaaaatc tccatatggt aagcaaattg ttccagaaat tcacccagaa
     2821 aaagtcaaag gagcaaatat cacatttgag catgatactt tcactatagg cgcaaattct
     2881 agctttgatt tgaatgcggt tataaatgtt ggagaggcca aaaacaaaaa taaatttgta
     2941 gaatcattta ttcattttga gtcagtggaa gaaatggaag ctctaaactc caacgggaag
     3001 aaaataaact tccaaccttc tttgtcgatg cctctaatgg gatttgctgg gaattggaac
     3061 cacgaaccaa tccttgataa atgggcttgg gaagaagggt caagatcaaa aacactggga
     3121 ggttatgatg atgatggtaa accgaaaatt ccaggaacct taaataaggg aattggtgga
     3181 gaacatggta tagataaatt taatccagca ggagttatac aaaatagaaa agataaaaat
     3241 acaacatccc tggatcaaaa tccagaatta tttgctttca ataaccaagg gatcaacgct
     3301 ccatcatcaa gtggttctaa gattgctaac atttatcctt tagattcaaa tggaaatcct
     3361 caagatgctc aacttgaaag aggattaaca ccttctccac ttgtattaag aagtgcagaa
     3421 gaaggattga tttcaatagt aaatacaaat aaagagggag aaaatcaaag agacttaaaa
     3481 gtcatttcga gagaacactt tattagagga attttaaatt ctaaaagcaa tgatgcaaag
     3541 ggaatcaaat catctaaact aaaagtttgg ggtgacttga agtgggatgg actcatctat
     3601 aatcctagag gtagagaaga aaatgcacca gaaagtaagg ataatcaaga tcctgctact
     3661 aagataagag gtcaatttga accgattgcg gaaggtcaat atttctataa atttaaatat
     3721 agattaacta aagattaccc atggcaggtt tcctatattc ctgtaaaaat tgataacacc
     3781 gcccctaaga ttgtttcggt tgatttttca aatcctgaaa aaattaagtt gattacaaag
     3841 gatacttatc ataaggtaaa agatcagtat aagaatgaaa cgctatttgc gagagatcaa
     3901 aaagaacatc ctgaaaaatt tgacgagatt gcgaacgaag tttggtatgc tggcgccgct
     3961 cttgttaatg aagatggaga ggttgaaaaa aatcttgaag taacttacgc aggtgagggt
     4021 caaggaagaa atagaaaact tgataaagac ggaaatacca tttatgaaat taaaggtgcg
     4081 ggagatttaa ggggaaaaat cattgaagtc attgcattag atggttctag caatttcaca
     4141 aagattcata gaattaaatt tgctaatcat gctgatgaaa aggggatgat ttcttattac
     4201 ctagtagatc ctgacaaaga tgcttctaaa tatgaaaaac ttggtgaaat ttctgaagat
     4261 aaactcaaaa atgcaaagag cccagaggaa aataccaata ataatcaagc taaggatgaa
     4321 gattcaaaac cagatgaaaa aagttcagtt gagggagaag ctagccttga aataaataaa
     4381 actatttcaa caattagaga gtttgaaaat aaagacctaa agaaactcat taaaaagaaa
     4441 tttagagaag ttgatgattt tacaagtgaa actggtaaga gaatagagga atacgattat
     4501 aaatacgatg ataagggaaa tattattgct tatgacgatg gtagtgcctt acaatatgaa
     4561 actgaaaaac ttgacgaaat aaaatcaaaa atttatggtg ttctaagccc atctaaagat
     4621 ggacactttg aaattcttgg aaagataagc aatgtttcta aaaatgccaa ggtatattat
     4681 ggaaatagct ataaatcgat agaaatcaaa gcgactaagt atgattcaca ttcaaaaacg
     4741 atgatatttg atttatacgc taatattaat gatattgtag atggattagc ttttgctgga
     4801 gatatgagat tatttgttaa agatgacaat caaataaaag ctgaaactaa gattagaatg
     4861 cctgaaaaaa ataaggaaac taaagcagaa tatccctatg tatcaagtta tgggaatgta
     4921 atcgaattag gagaaggaga tctttcaaag aacaaaccag acaatttaac taaaatggaa
     4981 tctggtaaaa tctattctga ttcagaaaaa caacaatatc tgttaaagga taacatcatt
     5041 ctaagaaaag gctatgcact aaaagtgact acctataatc ctggaaaaac ggatatgtta
     5101 gaaggaaatg gagtctatag caaggaagat atagcaaaaa tacaaaaggc caatcctaat
     5161 ctaagagtcc tttcagaaac aacaatttat gctgatagta gaaatgttga agatggaaga
     5221 agtacccaag ctgtattaat gtcggctttg gacggcttta acattataag gtatcaagtg
     5281 tttacattta aaatgaacga taaaggggaa gctatcgata aagacggaaa tcttgtgaca
     5341 gattcttcta aacttgtatt atttggtaag gatgataaag aatacactgg agaggataag
     5401 tccaatgtag aagctataaa agaagatggc tccatgttat ttattgatac caaaccagta
     5461 aacctttcaa tggataagaa ctactttaat ccatctaaat ctaataaaat ttatgtacga
     5521 aatccagaat tttatttaag aggtaagatt tctgataagg gtggttttaa ctgggaattg
     5581 agagttaatg aatcggttgt agataattat ttaatctacg gagatttaca cattgataac
     5641 actagagatt ttaatattaa gctgaatgtt aaagacggtg acatcatgga ctggggaatg
     5701 aaagactata aagcaaacgg atttccagat aaggtaacag atatggatgg aaatgtttat
     5761 cttcaaactg gctatagcga tttgaatgct aaagcagttg gagtccacta tcagttttta
     5821 tatgataatg ttaaacccga agtaaacatt gatcctaagg gaaatactag tatcgaatat
     5881 gctgatggaa aatctgtagt ctttaacatc aatgataaaa gaaataatgg attcgatggt
     5941 gagattcaag aacaacatat ttatgtaaat ggaaaagaat atacatcatt tgatgatatt
     6001 aaacaaataa cagacaagac actaaacatt aagattgttg taaaagattt tgcaagaaat
     6061 acaaccgtaa aagaattcat tttaaataaa gatacgggag aggtaagtga attaaaacct
     6121 catagggtaa ctgtgaccat tcaaaatgga aaagaaatga gttcaacgat agtgtcggaa
     6181 gaagatttta ttttacctgt ttataagggt gaattagaaa aaggatacca atttgatggt
     6241 tgggaaattt ctggtttcga aggtaaaaaa gacgctggct atgttattaa tctatcaaaa
     6301 gataccttta taaaacctgt attcaagaaa atagaggaga aaaaggagga agaaaataaa
     6361 cctacttttg atgtatcgaa aaagaaagat aacccacaag taaaccatag tcaattaaat
     6421 gaaagtcaca gaaaagagga tttacaaaga gaagatcatt cacaaaaatc tgattcaact
     6481 aaggatgtta cagctacagt tcttgataaa aacaatatca gtagtaaatc aactactaac
     6541 aatcctaata agttgccaaa aactggaaca gcaagcggag cccagacact attagctgcc
     6601 ggaataatgt ttatagtagg aatttttctt ggattgaaga aaaaaaatca agattaagac
     6661 aaaagctata gaaaaaaatg gtttatgtac tgagattaga tagtgaggtg atgacatagt
     6721 tttgtgaaaa cagccattta taactcaatt atttagttta cttcactatt gatactattt
     6781 ggagttatta atggacttag tttagataac taatgaattg attgaaaggg ttagtattga
     6841 caatattggt catattgatt agaaaataga gtctatcaaa atttaaaggc taatagaggt
     6901 gatgagacaa tttcggctct ttgtcaactg tagtgggttg aagtcagcta agctcgagaa
     6961 aggacaaatt ttgtcctttc ttttttgata ttcagagcga tgaaaatccg ttttttgaag
     7021 ttttcaaagt t
//
LOCUS       DAVBDR010000079         6834 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.079, whole genome shotgun sequence.
ACCESSION   DAVBDR010000079 DAVBDR010000000
VERSION     DAVBDR010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6834)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6834)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6834
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.079"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            complement(201..1625)
                     /locus_tag="VQ540_001942"
     CDS             complement(201..1625)
                     /locus_tag="VQ540_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent glyceraldehyde-3-phosphate
                     dehydrogenase"
                     /protein_id="HET2545695.1"
                     /translation="MTRYQNLVNGKWKSSEQEITIYSPINQEELGTVPAMTQTEADEA
                     MQAARAALPAWRALSAIERAAYLHKTAAILERDKEKIGTILAKEVAKGIKAAIGEVVR
                     TADLIRYAAEEGLRITGQAMEGGGFEAASKNKLAVVRREPVGIVLAIAPFNYPVNLSA
                     SKIAPALIAGNVVMLKPPTQGSISGLLLAKAFEEAGIPAGVFNTITGRGSEIGDYIIE
                     HKEVNFINFTGSTPIGERIGRLAGMRPIMLELGGKDAALVLEDADLEHAAKQIVAGAF
                     SYSGQRCTAIKRVIVLESVADKLATLLQEEVSKLTVGDPFDNADITPVIDNASADFIW
                     GLIEDAQEKEAQALTPIKREGNLLWPVLFDQVTKDMKVAWEEPFGPVLPIIRVASVEE
                     AIAFANESEFGLQSSVFTNDFKKAFEIAEKLEVGTVHINNKTQRGPDNFPFLGVKGSG
                     AGVQGIKYSIEAMTNVKSIVFDVK"
     gene            complement(2169..4448)
                     /gene="pulA"
                     /locus_tag="VQ540_001943"
     CDS             complement(2169..4448)
                     /gene="pulA"
                     /locus_tag="VQ540_001943"
                     /EC_number="3.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pullulanase"
                     /protein_id="HET2545696.1"
                     /translation="MYNYPMRIHYHRKNGEYDTCSFVKSQDQRIDLLTYKEDYFGALF
                     SFEHPSSHVIESLNFVVHTGQTSKEYSIRFNHYPLLTEVWILEGDDRIYYSENPAIAS
                     PFYKNQNPFAFDKAINSASFDHHWGYQGELGCRVEDNQAHFSLWSPTATEVQVVVYES
                     AANDAPVWKTFEMKRGNSYSYNHKDNTIGVWSLDVEEDLVGKTYQYQVQFPHHQTLTR
                     DPYTIATSPDGKRSAILSHVEKQVENFEVKHGSEATWRLENPCKAVICEMHIRDLTKS
                     PTSGVDEHLRGTFLGAAQAGTVNQYGQSTAFDYIKKLGYNYVQLQPIADRHKEYDEDG
                     NVTYNWGYDPQNYNAPETSFSTNPDDPAQVIRDLKVMVQAYHDAGIGVIMDVVYNHTF
                     SVVDAPFQTTVPDYYYRMNPDGTFQNGTGVGNETASEHEMFRKYMIDSLLYWVQEYNI
                     DGFRFDLMGIHDVKTMQMIRQSLDEIDSNIILYGEGWDMGTGLAPYDKAKKDNAYQMP
                     NIGFFNDNQRDAVKGGEVYGAIKSGFVSGAATEPILAKAILGSRELGSYTHPNQVLNY
                     VEAHDNYNLHDLLATLHPDQSSEQIMRKVETATAMNLLMQGMAFMEIGQEFGRTKLVA
                     TGENGELTHDDRERAMNSYNAPDSVNQVNWNLINERQDSIEFIRQVIRLKTKTGAFSY
                     SSYDEIYHHVFVHSAIEHSGCLIYEVHGKEHLLVVVNAKSEPYQFENAGNLAMLVTNS
                     RSKEDNVLNDISLAVLSVL"
     gene            complement(4560..6518)
                     /gene="ligA"
                     /locus_tag="VQ540_001944"
     CDS             complement(4560..6518)
                     /gene="ligA"
                     /locus_tag="VQ540_001944"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HET2545697.1"
                     /translation="MNKRMNELVALLNRYATEYYTSDNPSVSDSEYDRLYRELVELET
                     AYPEQVLADSPTHRVGGKVLDGFEKYSHQYPLYSLQDAFSREELDAFDARVRKEVAHP
                     TYICELKIDGLSISLTYEKGILVAGVTRGDGSIGENITENLKRVKDIPLTLPEELDIT
                     VRGECYMPRASFDQVNQVRQENGEPEFANPRNAAAGTLRQLDTAVVAKRNLATFLYQE
                     ASPSTRDSQEKGLKYLEQLGFVVNPKRILAENIDEIWNFIQEVGQERENLPYDIDGVV
                     IKVNDLASQEELGFTVKAPKWAVAYKFPAEEKEAQLLSVDWTVGRTGVVTPTANLTPV
                     QLAGTTVSRATLHNVDYIAEKDIRKDDTVIVYKAGDIIPAVLRVVESKRVSEEKLDIP
                     TNCPSCNSDLLHFEDEVALRCINPRCPAQIMEGLIHFASRDAMNITGLGPSIVEKLFA
                     ANLVKDVADIYRLQEEDFLLLEGVKEKSAAKLYQAIQASKENSAEKLLFGLGIRHVGS
                     KASQLLLQYFHSIENLSQADSEEVASIESLGGVIAKSLQTYFATEGSEILLRELKETG
                     VNLDYKGQTVVADAALSGLTVVLTGKLERLKRSEAKSKLESLGAKVTGSVSKKTDLVV
                     VGADAGSKLQKAQELGIQVRDEAWLESL"
     gene            complement(6611..>6834)
                     /locus_tag="VQ540_001945"
     CDS             complement(6611..>6834)
                     /locus_tag="VQ540_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001083019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HET2545698.1"
                     /translation="FFTQVQTKVESEFLGRVLSTIFTLAILFMPIAKGFMTVLPSVHL
                     SSFLIIGSGVIILSCISFIYVRTHFEKLI"
BASE COUNT         2022 a         1502 c         1239 g         2071 t
ORIGIN      
        1 actatatata gtaaaatgaa ataataacag gacaaatcga tcaggacagt caaatcgatt
       61 tctaacaatg ttttagaagt aaatctgtac tattctagtt tcaatatact ataataccaa
      121 aaagttcgta ttttttctat aattattatt attttatagc aaaaaataaa accaggaaaa
      181 caatttcctg attttacacg ttatttcaca tcaaaaacaa tggatttgac atttgtcatc
      241 gcttcaatgc tatatttaat tccttgcact ccagctccag aacctttgac accaaggaat
      301 gggaaattat ctggaccacg ctgggtttta ttattaatgt ggactgtacc tacttcaagt
      361 ttttcagcaa tttcaaaggc ttttttgaaa tcatttgtaa agactgatga ttgaaggccg
      421 aattcagatt cgttggcaaa ggcaatagct tcctctacac tagccacacg aatgattggt
      481 aaaacaggac caaatggctc ttcccatgcc actttcatat cttttgtaac ttggtcaaaa
      541 agcactggcc agaggagatt gccctcacgt ttgattggtg taagagcctg agcctctttt
      601 tcttgtgcat cctcaatcaa gccccaaatg aagtcggctg aagcattgtc aataacaggt
      661 gtaatatcag cattgtcaaa tggatcacca actgttaatt tagaaacttc ttcctgaagc
      721 aaagtagcta atttatctgc tacactttcg agaacaatga cacgtttaat ggccgtgcaa
      781 cgttgtcctg agtagctaaa ggctcccgca acaatttgct tggcagcatg ttccaaatct
      841 gcatcttcta gtacaagagc tgcatctttc ccaccaagtt ccaacatgat aggacgcata
      901 ccagctaaac gaccaatacg ttctccaata ggagttgaac ctgtaaagtt gatgaagttg
      961 acttctttgt gctcaatgat ataatcccca atttctgaac cacgacctgt aatggtgttg
     1021 aaaacacctg ccggaatccc tgcttcttca aatgctttag ccaacaagag tccagaaatg
     1081 gaaccttgtg ttggtggctt caacatgacc acattccctg caatcaaggc aggtgcaatt
     1141 ttagaagcag ataaattaac tggataatta aagggagcaa tcgctagcac gataccaact
     1201 ggttcacgac ggacaacagc cagtttgttt ttacttgctg cctcaaaacc accaccttcc
     1261 attgcttgtc cagtgatacg gagaccttcc tcagcagcat aacgaatcaa gtctgctgta
     1321 cgcactactt ctccaattgc tgctttaatc ccttttgcta cttctttggc aaggatagta
     1381 ccaatttttt ccttatcgcg ttctaaaata gctgctgttt tatgcaaata agccgcacgt
     1441 tcaattgctg ataaagctcg ccatgctggc agggctgcac gcgcagcttg catagcctca
     1501 tcagcttcag tctgagtcat ggctggaact gtacccaatt cttcttgatt gattggtgaa
     1561 taaatcgtaa tttcttgttc agatgatttc cattttccat ttactaaatt ctgatatctt
     1621 gtcaaattct tgtcctcctg aaaatgatta agatatattt taccaaattt tcagaaaata
     1681 acaacccttt ttgcaaaatt tttgagatta ttttcacaag cttgattttt caaagtatac
     1741 tcaataaaaa taaaaaaatc cactacgtca aggcgaggct aatgtggttt gaagaaattt
     1801 tcgaagagcg tgaatgagta tcatctatag taaaataaaa aaactgaaca atttggttgg
     1861 ggacagccaa accaatttct cacaatgttt cagaaacaag ggtgtgctat tccaatttca
     1921 gcctactata actgtcatag attgctgaaa caaagtctag gtaaaagtct tcataataaa
     1981 aagacctcct atcaaatgtt caaaaacttt gataggaggt cttgtttcgt gaaaatattt
     2041 atcaaatttt ctatacaagt gagctgttag ccaggttctt tctattcttt caatttcaat
     2101 gaatggattt tttaccaata ctcataactg ggaatttttc tgtctaaaaa tagcgagata
     2161 gatggtattt ataaaacact caagacagct agactaatat catttaaaac attatcttct
     2221 tttgagcgac tgttggttac caacatagct aaatttcctg cattttcaaa ttgatagggt
     2281 tctgatttag cattcacaac taccaagagg tgttctttgc cgtgaacttc atagataagg
     2341 cagccgctat gttcaatcgc agaatgcaca aagacatgat ggtaaatttc atcatagcta
     2401 gagtaagaaa aggcaccagt ttttgtcttc aatcggatga cttgacggat aaactcaata
     2461 ctgtcttgac gctcattaat caagttccag ttcacttggt tcacactgtc aggagcatta
     2521 tagctattca tcgcacgctc tctatcatca tgggtcaact caccattttc accagtcgca
     2581 accagtttgg tacgaccaaa ttcttgaccg atttccataa aggccatccc ctgcatgagc
     2641 agattcatgg ctgtggcagt ttcgaccttg cgcatgattt gctctgaact ttggtctgga
     2701 tgaagggttg ccaataaatc gtgaagattg taattgtcat gggcttctac atagttaagc
     2761 acctgatttg gatgtgtata gcttcctaat tcacgacttc ctaggattgc tttagctaga
     2821 attggctctg tcgcagcacc actgacaaaa cctgacttga tagcaccata aacttctccc
     2881 cctttgacag catcgcgctg attgtcatta aagaaaccaa tatttggcat ctggtaggca
     2941 ttgtccttct tggccttatc ataaggggca agacctgttc ccatatccca tccttctcca
     3001 tagaggataa tgttggagtc aatttcatcc aagctttgac gaatcatctg catggtcttg
     3061 acatcatgaa tccccatcaa gtcaaaacgg aagccgtcaa tattatattc ctgcacccag
     3121 tatagaagag aatcaatcat atacttgcga aacatttcgt gttcactggc tgtttcattt
     3181 ccaacacccg ttccattctg gaaggtacca tctggattca tacgataata gtaatcaggg
     3241 actgttgttt ggaatggtgc atcaacaact gagaaggtat ggttatagac tacatccata
     3301 atgactccaa tacccgcatc gtgataagct tgaaccatca ccttcaaatc acgaatgacc
     3361 tgagctggat catctggatt agttgaaaaa ctagtttctg gcgcgttata gttttgtgga
     3421 tcataacccc agttgtaggt tacatttcca tcctcatcgt attctttatg acggtctgca
     3481 attggttgca attgaacata attgtagccc agcttcttga tgtaatcaaa agcagttgac
     3541 tggccgtatt ggttaactgt tccagcctga gcagcaccca agaaagttcc tcgaagatgt
     3601 tcatctacac ccgatgtagg tgatttagtc aaatcacgaa tatgcatttc acagataact
     3661 gccttacatg gattttccaa gcgccaagta gcctccgaac cgtgcttaac ctcgaagttt
     3721 tcaacttgct tttctacatg gctcagaata gctgaacgtt tgccatcagg gctggtcgcg
     3781 attgtataag gatcacgtgt cagtgtttgg tgatgaggga attggacttg atactgataa
     3841 gtcttaccta ccaaatcttc ttcaacatcc aaactccaga caccgattgt attgtcctta
     3901 tgattataag agtagctatt gcctcttttc atctcaaaag tcttccaaac gggtgcatca
     3961 ttagcagctg attcataaac gacaacttgc acttctgtcg ctgtaggtga ccagagggaa
     4021 aaatgagcct gattgtcctc tacacggcaa cccaattctc cttggtaacc ccaatgatga
     4081 tcaaaactag cactgttaat ggccttatca aaggcaaaag gattttgatt tttatagaaa
     4141 ggactggcaa tagcaggatt ttcagagtaa taaatcctat catcgccttc caaaatccag
     4201 acctctgtta ataggggata gtgattaaaa cggatagaat attctttact agtttgacct
     4261 gtatgaacca caaaattcaa gctttctata acatgtgaac ttgggtgttc aaagctaaat
     4321 aaagctccaa aataatcttc tttgtaggtt agcaaatcaa ttcgttgatc ctgacttttt
     4381 acaaaggagc aagtgtcata ttctccattc ttacgatggt aatgaatgcg catagggtag
     4441 ttatacattt tttatttttc ctttttactt tgtttctatt tcactaataa atttttgtca
     4501 atctcgtctc aattaacaga catagtcata ttctctaaac tctgttttta aacgatccat
     4561 tacaaacttt ctagccatgc ctcatctctg acctggatac caagttcttg tgctttttgc
     4621 agtttacttc cagcgtctgc acctaccacg acgaggtcgg tctttttaga aacactacct
     4681 gtcactttgg cacccagact ttcgagttta cttttagctt ctgagcgctt gagtcgttcc
     4741 aattttcctg tcaataccac ggtcaaacct gacaaggccg catccgctac taccgtctgt
     4801 cctttatagt ccagattgac cccagtttct ttcaattctc tgagcagaat ttcagagcct
     4861 tctgtcgcaa aataagtctg aagacttttg gcaatcacgc cacctagact ttcaatacta
     4921 gccacttcct ctgaatctgc ctgagacaga ttttcaattg aatggaaata ttgaagtaaa
     4981 agctgactag ccttgcttcc gacatgacga attcccaaac caaataagag cttctcggca
     5041 gaattttcct ttgatgcttg gatagcctga tacagtttag cagcggactt ttccttaacc
     5101 ccctctaaaa ggaggaaatc ctcttcttgc aaacgataaa tatccgccac atccttgact
     5161 aaattagcag caaaaagctt ctcaacaata gatggaccaa ggcctgtaat attcatagca
     5221 tcacgagaag caaagtgaat caagccttcc atgatttgag cagggcaacg cggattgata
     5281 caacgtaggg ccacttcatc ttcaaagtgc aacaagtcag agttacaact tggacagttt
     5341 gtagggatat ctagtttttc ttcagaaacc cgtttggact ctaccacacg taaaacggca
     5401 gggatgatgt caccagcctt atatacaatg accgtatcgt cttttcggat atctttttca
     5461 gcaatataat ctacattgtg cagggtcgca cggctaacag tcgtaccggc aagttgtact
     5521 ggtgttagat tagcagttgg agttacaaca ccggtacggc caactgtcca gtcaactgat
     5581 aagagttgag cttctttttc ttcagcaggg aacttgtagg ctactgccca ctttggagcc
     5641 ttaacggtaa aaccaagttc ttcttgactt gctaggtcgt tgaccttgat taccactcca
     5701 tcaatatcgt aaggcagatt ttcccgttcc tgtcctactt cttggataaa attccagatt
     5761 tcatctatgt tttcagccaa gattcgctta ggattgacca caaaacctag ttgttctagg
     5821 tacttcaaac ccttttcttg gctatcacga gttgaagggc tggcttcttg atagagaaac
     5881 gttgcaagat tacgcttggc aactactgct gtatccaact gacgcagagt tcctgctgcc
     5941 gcattacgag gattagcaaa ttcaggctct ccattttctt ggcgcacttg gttaacttgg
     6001 tcaaaggaag cgcgtggcat gtaacattcc ccacgaactg tgatatctag ttcttctggc
     6061 aaagtcaaag ggatgtcctt aacacgcttg aggttttctg tgatattttc accaattgaa
     6121 ccatctccac gtgttacccc agcaaccaaa atcccctttt cataagtcag cgagatagat
     6181 aagccatcga ttttcagctc acaaatatag gtcggatgag ccacttcctt acgaacacgc
     6241 gcatcaaaag catctagctc ctcacgtgaa aaagcatcct gcaaactata aagaggatac
     6301 tgatgactgt atttttcaaa accatctaaa accttgccac caacacgatg agtcggactg
     6361 tctgctagca cttgctctgg ataagcagtt tctaactcga ccaactcacg gtaaaggcgg
     6421 tcatactcac tgtctgaaac cgagggatta tcgctggtat agtactcagt cgcatagcga
     6481 ttgagcaaag cgactaactc attcattctt ttattcataa gaccatttta ccataaaaca
     6541 agccctcctc acaaacgaga agggcggaaa aaacacttag tttgaaatta tttttgaaac
     6601 tcaagcaacc ttatatcaat ttttcaaaat gagttcgaac ataaataaac gatatacaag
     6661 acaagatgat aacaccactt ccaattatca ggaaagaaga gagatgtaca cttggcaaga
     6721 ctgtcataaa tccttttgca ataggcataa atagaatagc taaggtaaaa attgtactca
     6781 gtactcttcc aagaaattcg ctctcaacct tggtttgtac ttgagtaaaa aagt
//
LOCUS       DAVBDR010000080         6693 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.080, whole genome shotgun sequence.
ACCESSION   DAVBDR010000080 DAVBDR010000000
VERSION     DAVBDR010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6693)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6693)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6693
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.080"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            244..1110
                     /locus_tag="VQ540_001946"
     CDS             244..1110
                     /locus_tag="VQ540_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000537001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET2545699.1"
                     /translation="MGTLLATRLKNRRKELKMSQRELAEGICKQGQISRLESGEFTPG
                     ADFLHALAKKLKVSMDYFFDEQVVEKVEELSEFKKLAQTFITNRNYESLKYIYELENV
                     KAHRLSLADKIYMEWIKSLIDFYFYGQKEDAIVRLEGVLSQLSVSDLNYLQVSNTLFN
                     FYYDIGDLGRFNKIREKLEYQVNHLNLSTIEELELSIKFNYNVCRYLWLQKNIEEAIT
                     KITATIKQCKAYRTNYLLADLYLLMGNVSENFSSKSSVKEYFETAYFLYKLEENMSMT
                     LKVEHYIADITE"
     gene            1447..2004
                     /locus_tag="VQ540_001947"
     CDS             1447..2004
                     /locus_tag="VQ540_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase family
                     flavoprotein"
                     /protein_id="HET2545700.1"
                     /translation="MDKKNLLVLVTGSVGASNVDTYLYYIKKFYNVKVILSENSKKFI
                     SKELISYFCDKVYDEIFVEEVVPHVFLPYESDLLLILPATANVIGKIANGIADDLVTA
                     TVLNFNKKIIFCPNMNSTMWDNHIVQRNVSILKELGHIFLFESKKTYEVGLRKAIDST
                     CSMLQPQSLVKELIKLENIVLEEGH"
     gene            2225..3331
                     /locus_tag="VQ540_001948"
     CDS             2225..3331
                     /locus_tag="VQ540_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal-dependent decarboxylase"
                     /protein_id="HET2545701.1"
                     /translation="MINKKIQQVVLESLQNFLNGNFISPCVVYDFGLLETVLDEFKNQ
                     IPVTFNYQLFYAVKANSNEKILEFLVDKIDGVDVASLSELDVAKKFFPPTQISVNGPA
                     FSYETLYNLIKKQYKVDINFLEHLQQFSPKESVGIRVTEPDELNNRMSRFGINICSDN
                     WTSNLQNPLITRLHFHFGEKDDKFIVKLDKILFKLQEINKLREVREINLGGGFMKLFM
                     ENRFKEFFLSLMEIYKKYDIDSTVTTIIEPGSAITSFSAYMITSPVNVSEVNEQQVIT
                     LDTSIYTNTLWFVPHIITTLNSSSKERYSTILYGNTCYEHDKYKMKVSLPRLTQNSSI
                     VFFPVGAYIKSNHSNLHRNDFMREVYLWTKNLTY"
     gene            3307..4698
                     /locus_tag="VQ540_001949"
     CDS             3307..4698
                     /locus_tag="VQ540_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2545702.1"
                     /translation="MDKKLDILDKVKEYLGNKTTQILDNQYKEFLKLNDIRRAFGISE
                     KVLNNSFNFTSKEFNDLINNENYLFEYACRIREEWRKKCFNHSYRFLCSPIITDDFLN
                     TKTLRSSQIEYKYERYLSKSSIGDRAVDGFVSFNTLTANGMSAIKLCLEILNSIFFKK
                     KIDLLYSTGYYETRFLLNNLAKSGISCYEVSNCELDKDKFYNVFMMEPNRADLTLQKT
                     DFKIVEYFVKYKNNSIKVVILDISYQGSNFKLVEFLEKFKFANVIIFVVRSLIKLDQM
                     GLELTNGGIIEVFIPNHLRKLKNFIEEEFNKFRNSHGANLSLYEYCLLDNSLTLKNDW
                     NYSDLVMKFTSNFYADIKDLFMENSDIEIIHEEGVPFVFLDLIGEGKKEYEMFFQWLN
                     FFYKQLGITLYARNSFGFRNLTVEYFGIIGTERYIFKICPGVYKGLSYYLMKFLLKSF
                     SNEYLKTTDEVNR"
     gene            4695..5873
                     /locus_tag="VQ540_001950"
     CDS             4695..5873
                     /locus_tag="VQ540_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000792992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HET2545703.1"
                     /translation="MKNLIKLLIIRLIVNLADSVFYIVALWHVSNNYSSSMFLGIFIA
                     VNYLPDLLLIFFGPVIDRVNPQKILIISILVQLAVAVIFLLLLNQISFWVIMSLVFIS
                     VMASSISYVIEDVLIPQVVEYDKIVFANSLFSISYKVLDSIFNSFASFLQVAVGFILL
                     VKIDIGIFLLALFILLLLKFRTSNANIENFSFKYYKREVLQGTKFILNNKLLFKTSIS
                     LTLINFFYSFQTVVVPIFSIRYFDGPIFYGIFLTIAGLGGILGNMLAPIVIKYLKSNQ
                     IVGVFLFLNGSSWLVAIVIKDYTLSLILFFVCFMSKGVFNIIFNSLYQQIPPHQLLGR
                     VNTTIDSIISFGMPIGSLVAGTLIDLNIELVLIAISIPYFLFSYIFYTDNGLKEFSIY
                     "
     gene            6298..6531
                     /locus_tag="VQ540_001951"
     CDS             6298..6531
                     /locus_tag="VQ540_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000623387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HET2545704.1"
                     /translation="MISIDLGGTNIKITVLSNDGEIETLWSITTDTSEKGSQIISDII
                     SSIKNKLTERNIPDSDLLGIGMGSCSSYFPCKS"
BASE COUNT         2355 a          789 c         1196 g         2353 t
ORIGIN      
        1 gaaaggggct gaaagaacta ggggaacagt tgtaattaga aggtgatagg tatgaaaagt
       61 ggcgttgaag ctggataagt ttataaagag tttgaatgaa gaaatgaaaa gtaaataagt
      121 tgatgatgaa ttgcaaaaat agattttata tacaatttgt atctttcaaa tcattgattt
      181 gaattttaga tttaatcatg ttacaattaa aaatgaaatc aaatagaaga ggaagatgca
      241 aacgtgggca cactattagc aacaagatta aaaaatagac gaaaagaatt aaaaatgtct
      301 cagcgagaac tagctgaagg tatctgtaaa caggggcaaa tcagtcgatt agagagcgga
      361 gagtttactc ctggagcaga tttcttgcat gcccttgcta agaagttaaa agtcagtatg
      421 gattattttt ttgatgagca ggttgtagag aaagttgagg agttatcaga atttaagaaa
      481 ttagcacaga catttattac aaatcgcaat tatgagtctt tgaaatatat atatgaattg
      541 gagaatgtaa aagctcaccg cctatcttta gcagataaaa tctacatgga atggataaaa
      601 tctctgatag atttttattt ttacggacag aaagaagatg cgattgtacg attagagggg
      661 gtattatcac agttaagtgt atctgatttg aactatctcc aagtttcaaa caccctattc
      721 aatttttatt atgatattgg agatttaggt cgtttcaata aaattcgtga aaaactagag
      781 tatcaagtaa atcacctcaa tttgagtaca atcgaagagt tagaactatc tattaagttt
      841 aactacaacg tttgtcgtta tctatggtta cagaaaaata ttgaagaagc tattactaaa
      901 attacagcta ctataaaaca atgtaaggct tacagaacga attatctttt ggctgatttg
      961 tacttattga tgggaaatgt aagtgaaaat ttttcttcta aaagttcggt gaaagaatat
     1021 tttgagacgg catattttct atacaaactt gaggagaaca tgtcaatgac tctgaaagtt
     1081 gagcattaca ttgcagatat aacagaataa tgaatacggt gttcaagtga gcatcgtttt
     1141 tcaaacctag ttcagataca aaaaagtatc aaataaaaaa aaataaaaaa acattataaa
     1201 aacaattgac aagctaattt tgaagtgata aaataaatgc aagaaaacaa aaggagaggt
     1261 atatgagaag tttgtttaag aaaatagttg ctgtattagt tattggctta attctgttag
     1321 gaattgcgag aacacctcaa gttcataaga tggctagagg gattgatcct ggtcctgcga
     1381 attttattta gaaatcaatt tctactaatt gagtactaat tgagtattaa tgggtaaaaa
     1441 gattgtatgg ataagaaaaa tttacttgta ttggttactg gttcggtagg tgccagtaat
     1501 gtagatacat acttatatta tataaaaaaa ttctataatg ttaaagtgat actttctgaa
     1561 aattctaaaa aatttataag taaggaatta attagttatt tttgtgataa agtttatgat
     1621 gaaatatttg ttgaagaggt agttccgcac gtttttctgc catatgaatc tgacttactt
     1681 cttattttac cagctacggc aaatgtgatt ggcaaaattg ctaatggtat tgctgatgat
     1741 ttagttacag caactgtttt aaactttaat aaaaaaataa ttttttgtcc caatatgaac
     1801 tctactatgt gggacaatca catagttcaa agaaatgtat caattctaaa ggagttggga
     1861 catatatttt tatttgagtc taaaaaaaca tatgaggtag gattgcgtaa agcaatagat
     1921 tcaacatgtt caatgttaca accacagtcg ttagtaaaag aacttatcaa attagaaaat
     1981 attgtccttg aagagggaca ttaaaaacta ctgagaatat taaggagggg aaaaaatgga
     2041 aaattcatca atcgatgtag atatgctgtt ggaagaattg acacaagaag caatggtcgt
     2101 tgttgctgtt gataaggact gttaatttaa acttatggca atatatgaaa ggttactgga
     2161 tgttttaaat tatgcaggca gtagcctttt attatataca aatggataaa gtaaggataa
     2221 tacaatgatt aataaaaaaa tacaacaagt tgttttggaa tcattacaga attttttgaa
     2281 tgggaacttc atttcgcctt gtgtagtcta tgattttggc ttgctggaaa ctgtacttga
     2341 tgaatttaaa aatcaaattc ctgtaacatt caattaccaa cttttttatg ccgttaaagc
     2401 aaattcaaat gagaagatac ttgaattctt agtagataaa attgatggag ttgatgtggc
     2461 gtcattatct gaattagatg tggctaaaaa atttttccca ccaactcaaa tttctgttaa
     2521 tggtcccgca ttttcttatg aaactttata taatctgatt aaaaaacaat ataaagttga
     2581 tattaacttt ttggaacatc ttcaacaatt ttccccaaaa gaatctgttg gaataagagt
     2641 aacggagcca gatgaactta ataatcgtat gagtcgattt ggaataaata tttgcagtga
     2701 taattggact agtaatttac aaaatccttt aattacacga ctgcattttc attttggaga
     2761 aaaagatgat aaatttattg ttaagttaga taaaatatta tttaagttac aagaaattaa
     2821 taaacttaga gaggttagag aaataaatct tggaggcggt tttatgaaat tatttatgga
     2881 aaatcgtttt aaagaatttt ttctatcact tatggaaatc tataaaaagt acgatattga
     2941 tagtactgtg actacaataa tagaaccagg tagtgcaatt acttcatttt ctgcctatat
     3001 gattactagc ccagttaatg ttagtgaggt gaatgagcag caggttatca cgttagacac
     3061 atcaatatac accaatacat tatggtttgt tccgcatatt attacaacgt taaattcaag
     3121 tagtaaagag cgttatagta ctattctcta tggtaatacc tgttatgaac atgacaagta
     3181 taaaatgaaa gtttcgcttc caaggttaac tcaaaatagc agtatagtgt tttttcctgt
     3241 aggagcttat ataaaaagca atcattcaaa tttacatcgt aatgatttta tgcgggaggt
     3301 atatttgtgg acaaaaaact tgacatatta gataaagtta aggaatattt aggaaataaa
     3361 actactcaaa ttctggataa tcaatataaa gaatttttga aacttaatga tataaggcga
     3421 gcgtttggta tttcagaaaa agtattaaac aattctttta attttacgag taaagaattt
     3481 aatgatttaa ttaataacga aaattattta ttcgaatatg catgtagaat tagagaggaa
     3541 tggagaaaaa aatgctttaa tcattcttat cgttttctat gctcacctat aattacagat
     3601 gattttctta acacgaagac attgagaagt agccaaattg aatataaata tgagcgatat
     3661 ttatcgaaaa gttcgatagg cgatagagcg gttgatggct ttgtttcctt caatacttta
     3721 acagctaatg gtatgtctgc tattaaacta tgtcttgaga tattaaactc tattttcttc
     3781 aagaagaaga ttgatttatt atattcaacc ggatattatg aaacaagatt tttattaaat
     3841 aatcttgcta aatcaggtat tagttgctat gaggtaagta attgtgaatt ggataaagat
     3901 aaattttata atgtattcat gatggaaccc aatcgagccg atttaacatt acaaaaaact
     3961 gatttcaaga tagtagaata ttttgttaag tataaaaata attcaataaa agtcgttatt
     4021 ttagatattt catatcaagg ttctaatttt aaattagtag aatttttaga gaaatttaaa
     4081 tttgcgaatg taattatttt tgtggtacga tctttgataa aattagatca aatgggatta
     4141 gaattgacaa atgggggaat aatagaagtg tttattccta atcatttgag aaagttgaaa
     4201 aattttattg aagaggaatt caataaattt agaaattctc acggagctaa tctaagcctc
     4261 tatgaatact gtttgcttga taattcttta accttaaaaa atgattggaa ctattctgat
     4321 ttagttatga aatttacgag taatttttat gctgatataa aagacttgtt catggaaaat
     4381 tctgatattg aaatcatcca tgaagaggga gtaccttttg tatttttaga tttaataggt
     4441 gaaggtaaaa aagaatatga aatgtttttt caatggttaa acttctttta caaacagctt
     4501 ggaatcacat tgtatgctag aaatagtttt gggtttcgga atctaacagt agagtatttt
     4561 ggaattattg ggacagaaag atatatattt aagatttgtc caggtgttta taaagggtta
     4621 agttattatt tgatgaaatt tttattaaaa tctttttcaa atgaatattt aaaaactact
     4681 gatgaggtta atagatgaaa aatttgataa agttgctaat aattagattg attgttaact
     4741 tagcagacag tgtattttat atagtagcat tgtggcacgt tagcaataat tattcttcga
     4801 gcatgttctt aggaatattt attgcagtaa attatctacc ggatttgtta ctaatctttt
     4861 ttggaccagt tattgacaga gtaaatccgc aaaaaattct tataatatca attttggttc
     4921 aattagcagt ggctgtaata tttttattat tattaaacca aatatcattt tgggtgataa
     4981 tgagtctagt gtttatttca gtaatggcta gctccataag ttacgtgata gaagatgtgt
     5041 tgattcctca agtggtagaa tatgataaga ttgtatttgc aaattctctt tttagtattt
     5101 cgtataaagt attagattct atttttaatt cattcgcatc atttttacag gtggcagtag
     5161 gatttatttt attggttaag atagatatag gcatattttt acttgctcta tttatattgt
     5221 tgttgttaaa atttagaact agcaatgcga atatagaaaa cttctctttc aaatattaca
     5281 agagagaagt gttgcaaggt acaaagttta ttttaaataa taaattatta tttaaaacca
     5341 gtatttcttt aacgcttata aacttttttt attcatttca gacagtagtt gtaccgattt
     5401 tttctattcg atattttgat ggtccgattt tttatggtat ttttttaact attgctggtt
     5461 tgggtggtat attgggaaat atgctagcgc caatcgtaat aaaatattta aaatcgaatc
     5521 aaattgttgg tgtatttctt tttttgaacg gctcaagttg gttagtagca attgttataa
     5581 aagactatac tttatcactt attttatttt tcgtttgttt tatgtctaaa ggagtcttca
     5641 atattatttt taattcgttg taccaacaaa tacctccaca tcaacttctt ggtagggtaa
     5701 atactaccat tgattctatt atttcttttg gaatgccaat tggtagttta gttgcaggaa
     5761 cgcttattga tttgaatatt gaattagtgt taattgctat tagcatacct tattttttgt
     5821 tttcttatat tttttatacg gataatggat tgaaagaatt tagtatatat tagaaatgtt
     5881 tatgttcatt caaaagcata atgactataa ctgaaaaaga aaagtgatat ctttaaggtt
     5941 gttcttcttg gtggtgagat tcgtgagaca acccaagctt ttgtcggaaa gattaccaat
     6001 gctttgatgg ataggatgta ctttagcaag atgtttttag tggtaacggt atcgtggatg
     6061 gacgtgtaat aacctcttct ttcgaggagt attttactaa aaaactagcc ttggagcgtt
     6121 ccccagaaac ggacttactc attgactctt caaagatttg gggagaagat tttgcttcat
     6181 ctgttccttg aaaaaagtca cagcagtcat cacagacgat agtactgaac aaaactatga
     6241 agagttagaa atttatacgc aggtgattgt ataaaggatc tggaaataga taagaagttg
     6301 attagtattg acctaggtgg tacaaatatt aagattactg ttctttcaaa tgacggtgag
     6361 attgaaactt tgtggagtat tacaacagat acaagtgaga aaggttctca aattatatcg
     6421 gacatcatca gttctattaa aaataaattg accgaacgga atattcctga tagcgacctt
     6481 cttggaatcg gtatgggaag ttgctcatca tactttcctt gtaaatcata ggggctataa
     6541 actctccgtc tacttgtcct gcaacaattg aagtctgctc aaaacgccgt ccgctaatct
     6601 tttcatagac tttctccctt ttaggagcct agctttctag tttgttcttt gatttttatt
     6661 gagtatacca ctattttact ccctctggca agg
//
LOCUS       DAVBDR010000081         6498 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.081, whole genome shotgun sequence.
ACCESSION   DAVBDR010000081 DAVBDR010000000
VERSION     DAVBDR010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6498)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6498)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6498
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.081"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            complement(<1..148)
                     /locus_tag="VQ540_001952"
     CDS             complement(<1..148)
                     /locus_tag="VQ540_001952"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2545705.1"
                     /translation="MITHRRFISCNEIIKHYKRLIDKAEKCVNDLMAEFNSVITTVTG
                     IGNRL"
     gene            307..2073
                     /gene="patB"
                     /locus_tag="VQ540_001953"
     CDS             307..2073
                     /gene="patB"
                     /locus_tag="VQ540_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000859866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatB"
                     /protein_id="HET2545706.1"
                     /translation="MKTVQFFWHYFKVYKFSFVVVILMIVLATFAQALFPVFSGQAVT
                     QLANLVQAYQNGNPELVWQSLSGIMVNLGLLVLVLFISSVIYMCLMTHVIAESTNEMR
                     KGLFGKLAQLTVSFFDRRQDGDILSHFTSDLDNILQAFNESLIQVMSNIVLYIGLILV
                     MFSRNVTLALITIASTPLAFLMLIFIVKMARKYTNLQQKEVGKLNAYMDESISGQKAV
                     IVQGIQEDMMAGFLEQNERVRKATFKGRMFSGILFPVMNGMSLINTAIVIFAGSAVLL
                     NDKSIETSTALGLIVMFAQFSQQYYQPIIQVAASWGSLQLAFTGAERIQEMFDAEEEI
                     RPEKAPTFTKLQESVEISHIDFSYLPDKPILKDVSISAPKGQMTAVVGPTGSGKTTIM
                     NLINRFYDVDAGGIYFDGKDIRGYDLDSLRSKVGIVLQDSVLFSGTIRDNIRFGVPDA
                     SQEMVEVAAKATHIHDYIESLPDKYDTLIDDDQSIFSTGQKQLISIARTLMTDPEVLI
                     LDEATSNVDTVTESKIQHAMEVVVAGRTSFVIAHRLKTILNADQIIVLKDGEVIERGN
                     HHELLKLGGFYSELYHNQFVFE"
     gene            2212..2901
                     /locus_tag="VQ540_001954"
     CDS             2212..2901
                     /locus_tag="VQ540_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HET2545707.1"
                     /translation="MARTVVGVAANLCPVDAEGKIIHSSVSCRFAEIIRQVGGLPLVI
                     PVGDESVVRDYVEMIDKLILTGGQNVHPQFYGEKKTVESDDYNLVRDEFELALLKEAL
                     RQNKPIMAICRGVQLVNVAFGGTLNQEIEGHWQGLPFGTSHSIETVEGSVVAKLFGKE
                     SQVNSVHRQSIKDLAPNFRVTAIDSRDQTIEAIESIDEHRIIGLQWHPEFLVNEEDGN
                     LELFEYLLDEL"
     gene            2905..3084
                     /locus_tag="VQ540_001955"
     CDS             2905..3084
                     /locus_tag="VQ540_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2545708.1"
                     /translation="MEHLVVLSFIFSKFLECGILRKRLNSDKNWRNSTKKLEKNEGKR
                     YDRKEEILEEEHVTY"
     gene            3071..4420
                     /locus_tag="VQ540_001956"
     CDS             3071..4420
                     /locus_tag="VQ540_001956"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HET2545709.1"
                     /translation="MSHIKFDYSKVLDKFVAPHEVEYMQSQVTAADELIRKGTGAGSD
                     FLGWLDLPEKYDREEFDRILKAAEQIKSDSDVLVVIGIGGSYLGAKAAIDFLNHHFAN
                     LQTKEERKAPQILYAGNSISSTYLADLVEYVADKDFSVNVISKSGTTTEPAIAFRVFK
                     ELLVKKYGQEEANKRIYATTDRQKGAVKVEADANGWGTFVVPDDIGGRFSVLTAVGLL
                     PIAASGADIKALMEGANAARKDYTSDKISENEAYQYAAVRNILYRKGYATEILVNYEP
                     SLQYFSEWWKQLAGESEGKDQKGIYPTSANFSTDLHSLGQFIQEGTRIMFETVVRVDK
                     PRKNVLIPTLEEDLDGLGYLQGKDVDFVNKKATDGVLLAHTDGDVPNMYVTLPEQDAF
                     TLGYTIYFFELAIALSGYLNAINPFDQPGVEAYKRNMFALLGKPGFEELSKELNARL"
     gene            4544..6004
                     /locus_tag="VQ540_001957"
     CDS             4544..6004
                     /locus_tag="VQ540_001957"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HET2545710.1"
                     /translation="MSKDIRVRYAPSPTGLLHIGNARTALFNYLYARHHGGTFLIRIE
                     DTDRKRHVEDGERSQLENLRWLGMDWDESPESHENYRQSERLDLYQKYIDQLLAEGKA
                     YKSYVTEEELAAERERQEVAGETPRYINEYLGMSEEEKAAYIAEREAAGIIPTVRLAV
                     NESGIYKWHDMVKGDIEFEGGNIGGDWVIQKKDGYPTYNFAVVIDDHDMQISHVIRGD
                     DHIANTPKQLMVYEALGWEAPEFGHMTLIINSETGKKLSKRDTNTLQFIEDYRKKGYL
                     PEAVFNFIALLGWNPGGEDEIFSREELIKLFDENRLSKSPAAFDQKKLDWMSNDYIKN
                     ADLETIFEMAKPFLEEAGRLTDKAEKLVELYKPQMKSVDEIIPLTDLFFSDFPELTEA
                     EREVMTGETVPTVLEAFKAKLEAMTDDKFVTENIFPQIKAVQKETGIKGKNLFMPIRI
                     AVSGEMHGPELPDTIFLLGREKSIQHIENMLKEISK"
     gene            6018..6452
                     /locus_tag="VQ540_001958"
     CDS             6018..6452
                     /locus_tag="VQ540_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HET2545711.1"
                     /translation="MDIWEKMYEEAQKLYNPHEVSDFVYANHVVAAVEAEDGQIFTGF
                     CMEGTCGVFHLCAERAALFNTYQFSGQTKVKKVLAFRDKPPYGGSSAMPCGACREFLL
                     ELNAENKDAEFMMDYNIRKTVKVAELIPYWWGEERASKFNER"
BASE COUNT         2036 a         1251 c         1397 g         1814 t
ORIGIN      
        1 ctaaacgatt cccaatccca gtaaccgtcg tgatgaccga gttgaactca gccatcaagt
       61 cattgacaca tttttccgcc ttgtcaatga gcctcttgta atgtttgatg atttcattac
      121 acgagataaa acgtctatgc gttatcaaac tcattaccaa ttaaaacaaa aagctgtggt
      181 tagatccttt cggaaatcgt caagcgattg gaggaaatga actaatccac agcggcttat
      241 tccaagtata ccacttgggc tttggcagta gctaactgcg ctaaatataa tataaggagg
      301 agtaaaatga agacagttca atttttttgg cattatttta aggtctacaa gttctcattt
      361 gtagttgtca tcctgatgat tgttctggcg acttttgccc aagccctctt tccagtcttt
      421 tctggacaag cggtgacgca gctagccaat ttagttcaag cttatcaaaa tggcaatcca
      481 gaacttgtat ggcaaagcct atcaggaatc atggtcaatc ttggcctgct ggttttggtt
      541 ctatttatct ctagtgtaat atacatgtgt ctcatgacgc acgtgattgc agaatcgacc
      601 aacgagatgc gcaaaggcct ctttggtaag cttgctcagt tgacggtttc tttctttgac
      661 cgtcgacaag atggcgatat cttgtctcat tttaccagtg atttggataa tatcctccaa
      721 gcctttaacg aaagcttgat tcaggtcatg agcaatattg ttttatacat tggtctgatt
      781 cttgtcatgt tttcgagaaa tgtgacgctg gctctcatca ccattgccag caccccattg
      841 gctttcctta tgctgatttt catcgtgaaa atggcacgca aatacaccaa cctccagcag
      901 aaagaggtag ggaagctcaa cgcctatatg gatgagagca tctcaggcca aaaagccgtg
      961 attgtgcaag gaattcaaga ggatatgatg gcaggatttc ttgaacaaaa tgagcgcgtg
     1021 cgcaaggcaa cctttaaagg aagaatgttc tcaggaattc ttttccctgt catgaatggg
     1081 atgagcctga ttaatacagc catcgtcatc tttgctggtt cggctgtact tttgaatgat
     1141 aagtctattg aaacaagtac agccctaggt ttgattgtta tgtttgcaca attttcacag
     1201 cagtactacc agcctattat ccaagttgca gcgagttggg gaagccttca gttggccttt
     1261 actggagctg aacgaattca ggaaatgttt gatgcagagg aggaaatccg acctgaaaag
     1321 gctccaacct tcactaagtt gcaagaaagt gttgaaatca gtcatatcga tttttcatac
     1381 ttgcctgata aacctatttt gaaagatgtc agcatttctg cccctaaagg ccagatgaca
     1441 gcagttgttg ggccgacagg ttcaggaaaa acgactatta tgaacctcat caatcgcttt
     1501 tatgatgttg atgctggtgg tatttatttt gatggtaaag acattcgtgg ctatgactta
     1561 gatagtctta gaagcaaggt gggaattgta ttgcaagatt cggtcttgtt tagcggaacg
     1621 attcgagaca atatccgatt tggtgtgcca gatgctagtc aggaaatggt tgaggtagca
     1681 gcaaaagcaa cccacattca cgactatatc gaaagtttgc ctgataagta cgatactctt
     1741 attgatgatg accagagcat cttttcaaca gggcagaagc aattgatttc aatcgctcga
     1801 accctgatga cagatccaga agttctcatt ctcgatgaag caacttcaaa cgtagatacg
     1861 gtgacagaaa gcaagattca gcatgccatg gaggtggttg tagcaggtag aactagtttc
     1921 gtcattgccc accgcttgaa aaccattctc aatgcagatc agattattgt ccttaaagat
     1981 ggagaagtca ttgaacgtgg taaccaccat gaacttttga agctaggtgg cttttattca
     2041 gaactctatc acaatcaatt tgttttcgaa taagaaagaa gttgtcctat gtgggcagct
     2101 ttttcttgtc cataaaaaat gtttatcaca gccttaaaaa aaacatatta gacgaaagtc
     2161 attttgagtg atatgatagg actatcgtta gcattcgaaa ggagaggcat catggctaga
     2221 acggttgtag gagttgctgc aaatctatgt cccgtagacg cagaaggcaa aatcattcat
     2281 tcatctgtat cttgtagatt cgcagagatc attcgtcaag tcggtggtct ccctttagtc
     2341 attcctgttg gtgatgagtc agttgtacgt gattatgtgg aaatgattga caaactcatt
     2401 ttgacaggag gccaaaatgt tcatcctcag ttttatggag agaaaaagac cgtcgagagc
     2461 gatgattaca atctggtccg tgacgaattt gaattggcac tcttgaagga agcgcttcgt
     2521 cagaataaac caattatggc aatctgtcgc ggtgtccaac ttgtcaatgt tgcctttggt
     2581 ggaaccctca atcaagaaat cgaaggtcac tggcaaggac tacctttcgg gacatctcac
     2641 tctattgaga cagtagaagg aagcgtggtg gctaagctat ttgggaaaga aagtcaggtc
     2701 aactcagtcc atcgtcaaag cattaaagat ttggcaccta atttccgtgt aactgctatt
     2761 gattcaagag accaaactat tgaagcgatt gagtctatcg acgagcaccg cattatcggt
     2821 ttacagtggc atccagagtt tctggttaat gaagaagatg gcaatttaga attatttgag
     2881 tatttattgg atgaactgta acaattggaa catctggtcg ttctttcttt tattttttca
     2941 aaatttttag aatgtggtat tttacgcaaa cgtttgaatt ctgataaaaa ttggagaaat
     3001 tcgacaaaaa aacttgaaaa aaacgaaggt aagcgttatg atagaaaaga agaaatattg
     3061 gaggaagaac atgtcacata ttaaatttga ttattcaaaa gttttagaca aatttgttgc
     3121 accacatgaa gtggaataca tgcaatcaca agtaacagca gcagatgaat tgatccgtaa
     3181 aggaactggt gctggtagcg acttcttggg atggttggac cttcctgaaa aatacgaccg
     3241 cgaagaattt gaccgcatct tgaaagctgc tgagcaaatc aagtcagaca gcgatgtttt
     3301 ggttgtgatc ggtattggtg gatcttacct tggtgcaaaa gcagcaatcg acttcttgaa
     3361 tcaccatttt gctaacttgc aaacaaaaga agaacgcaaa gctccacaaa tcctttacgc
     3421 aggaaactca atctcatcta cttaccttgc tgacttggta gagtatgttg cagacaaaga
     3481 cttctcagta aacgtaattt ctaaatcagg tacaacaact gaaccagcga ttgctttccg
     3541 tgtctttaaa gaactcttgg ttaagaaata cggtcaagaa gaagctaaca aacgtatcta
     3601 tgcaacaact gaccgccaaa agggtgctgt taaggttgaa gcagacgcta acggttgggg
     3661 aacatttgtt gttccagatg atatcggtgg acgcttctca gtattgacag ccgttggttt
     3721 gcttccaatc gcagcatcag gagctgacat aaaagctctt atggaaggtg cgaatgcagc
     3781 tcgcaaagac tacacttcag acaaaatctc tgaaaacgaa gcttaccaat acgcagctgt
     3841 tcgtaacatc ctttatcgta aaggctatgc aactgagatc ttggtaaact atgagccatc
     3901 acttcaatac ttctcagaat ggtggaaaca attggctggt gaatcagaag gaaaagacca
     3961 aaaaggtatc tacccaactt cagccaactt ctcaactgac ttgcactcac ttggtcaatt
     4021 tatccaagaa ggaactcgta tcatgtttga aacagttgtc cgtgttgaca aacctcgtaa
     4081 aaacgtgctt attcctactt tggaagaaga ccttgacgga cttggttacc ttcaaggaaa
     4141 agacgttgac tttgtaaaca aaaaagcaac tgacggtgtt cttcttgccc acacagatgg
     4201 tgatgtacca aacatgtatg tgactcttcc agagcaagac gctttcactc ttggttacac
     4261 tatctacttc ttcgaattgg caattgccct ttcaggttac ttgaatgcta tcaacccatt
     4321 tgaccaacca ggtgttgaag cttataaacg taacatgttt gcccttcttg gaaaaccagg
     4381 atttgaagaa ttgagcaaag aacttaacgc acgtctataa tagaagaaaa gagtggtttg
     4441 cccactcttt ttactctctt tatccataga aattggactc agccaagact tgtgatataa
     4501 tatagaaagc aaaaaggcag acgcctagat aataggagaa actatgtcaa aagatatccg
     4561 cgtacgttac gcaccaagtc caacaggact actacacata ggaaatgctc gtacagcatt
     4621 gtttaattac ttgtatgcgc gccatcatgg tggaacattt ctcatccgta tcgaagatac
     4681 tgaccgtaaa cgccatgtcg aggatggtga acgttcacaa cttgaaaacc ttcgctggtt
     4741 aggcatggat tgggatgaaa gtccagaatc acatgagaat tatcgccagt ctgagcgttt
     4801 ggacttgtat caaaaataca tcgaccaact attagctgaa ggaaaagcct acaaatctta
     4861 cgttacagaa gaagagttgg cagctgaacg tgaacgtcaa gaagtagctg gcgaaacacc
     4921 acgctacatc aatgaatacc ttggtatgag tgaagaagaa aaagcagctt acatcgcaga
     4981 acgtgaagca gcagggatca tcccaactgt tcgtttggct gtcaatgagt caggtatcta
     5041 caagtggcat gatatggtca aaggcgatat cgaatttgaa ggtggcaata tcggtggtga
     5101 ctgggttatc caaaagaaag acggttaccc aacttacaac tttgccgttg ttatcgatga
     5161 ccacgatatg caaatctctc atgttatccg tggagatgac catattgcta atacaccaaa
     5221 acagcttatg gtctatgaag ctcttggttg ggaagctcca gagttcggtc acatgacctt
     5281 gattatcaac tctgagactg gtaagaagtt atctaaacgt gatactaata cacttcaatt
     5341 tatcgaagat taccgaaaga aaggttacct tccagaagca gtctttaatt ttattgctct
     5401 tcttggttgg aacccaggtg gtgaagatga gattttctct cgtgaagaac tcattaaact
     5461 ttttgatgaa aaccgcctca gcaagtcacc agcagccttt gatcagaaaa aactagactg
     5521 gatgagcaat gattatatca agaatgcaga ccttgaaacc atctttgaaa tggcaaaacc
     5581 attcttagag gaagcaggcc gtttgactga caaggctgaa aaattagttg agctctataa
     5641 accacaaatg aaatcagtag atgagattat cccattgaca gatcttttct tctcagattt
     5701 cccagaattg acagaagcag agcgcgaagt catgacgggt gaaacagttc caacagttct
     5761 tgaagcattc aaagcaaaac ttgaagcgat gacagatgat aaatttgtga cagaaaatat
     5821 cttcccacaa attaaagcag ttcaaaaaga aacaggtatt aaagggaaaa atcttttcat
     5881 gcctattcgt atcgcagttt caggcgaaat gcatgggcca gaattaccag atacaatttt
     5941 cttgcttgga cgtgaaaaat caattcagca tatcgaaaac atgctaaaag aaatctctaa
     6001 ataaagagga tacaataatg gacatctggg aaaagatgta cgaagaagca cagaaactat
     6061 acaatccaca tgaagtatca gactttgttt atgccaatca tgttgtagct gcagtagaag
     6121 cagaagatgg acaaatattt acaggattct gtatggaggg aacctgtggt gttttccatc
     6181 tctgcgcaga acgggcggcc ctcttcaata cgtaccaatt ttcaggacaa actaaggtta
     6241 agaaagtatt agcctttcga gacaaaccac cttatggtgg aagttcagcc atgccttgcg
     6301 gtgcttgtag agaattcctt ttagagctta atgctgaaaa taaagatgca gaattcatga
     6361 tggactataa tataagaaaa acagttaaag tcgcagaact aatcccttat tggtggggag
     6421 aagaacgtgc ttctaagttt aatgagcgat agaagagtca gtataattct ggcttttttt
     6481 actataagtt gaaaaaat
//
LOCUS       DAVBDR010000082         6482 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.082, whole genome shotgun sequence.
ACCESSION   DAVBDR010000082 DAVBDR010000000
VERSION     DAVBDR010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6482)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6482)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6482
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.082"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            59..1021
                     /locus_tag="VQ540_001959"
     CDS             59..1021
                     /locus_tag="VQ540_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HET2545712.1"
                     /translation="MNMSNITIDGQEMDLSQTMPSYAQVVSLYDDTSISVSSNETDKV
                     LAGSLYTDTNEQGLTIPSSLLKNWNEQTGKNLTANDLIGKSVSASIVESAAETSKIAQ
                     FQTKIVRVINDEDDMEDSNSFMLSHQMETILKEAGFTKAVSYFILELKDPSQTKVVTE
                     ELQKNKKYTVLSQQRVLDIVIIFIRVIQGLLIVLSSQAIVVAAVMIGIIIYINIMQRS
                     KEIGVMKAVGYQNRDVKGIFIYEAIWIVGIALLLAFLVAQGVGSLANAIVSHFYPSIT
                     KVFELNLLSVLGTLVFALLLGYVSAYFPARKISKMDPVEPLRYE"
     gene            1198..2205
                     /gene="gap"
                     /locus_tag="VQ540_001960"
     CDS             1198..2205
                     /gene="gap"
                     /locus_tag="VQ540_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HET2545713.1"
                     /translation="MVVKVGINGFGRIGRLAFRRIQNVEGVEVTRINDLTDPVMLAHL
                     LKYDTTQGRFDGTVEVKEGGFEVNGKFIKVSAERDPEQIDWATDGVEIVLEATGFFAK
                     KEAAEKHLKGGAKKVVITAPGGNDVKTVVFNTNHDVLDGTETVISGASCTTNCLAPMA
                     KALQDNFGVVEGLMTTIHAYTGDQMILDGPHRGGDLRRARAGAANIVPNSTGAAKAIG
                     LVIPELNGKLDGSAQRVPTPTGSVTELVAVLEKNVTVDEVNAAMKAASNESYGYTEDP
                     IVSSDIVGMSYGSLFDATQTKVLDVDGKQLVKVVSWYDNEMSYTAQLVRTLEYFAKIA
                     K"
     gene            complement(2272..3108)
                     /locus_tag="VQ540_001961"
     CDS             complement(2272..3108)
                     /locus_tag="VQ540_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000216776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HET2545714.1"
                     /translation="MTVKQLLEEQLLIPRKIRHFLRIKKHILINQEEVHWNEIVNPGD
                     VCQLTFDEEDYPQKTIPWGNPDLVQEVYQDQYLIIVNKPEGMKTHGNQPNEIALLNHV
                     STYVGQTCYVVHRLDMETSGLVLFAKNPFILPILNRLLEKKEISREYWALVDGNINRK
                     ELVFRDKIGRDRHDRRKRIVDAKNGQYAETYVSRLKQFSNKTSLARCKLKTGRTHQIR
                     VHLSHHNLPILGDPLYNSKSKTSRLMLHAFRLSFTHPLTLEKLTFTTLSNTFEKELKK
                     NG"
     gene            3234..5429
                     /locus_tag="VQ540_001962"
     CDS             3234..5429
                     /locus_tag="VQ540_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HET2545715.1"
                     /translation="MKLDKLFEKFLSLFKKETSELEDSDSTILRRSRSDRKKLAQVGP
                     IRKFWRRYHLTKIILILGLSAGLLVGIYLFAVAKSTNVNDLQNALKTRTLIFDREEKE
                     AGALSGQKGTYVELTDISKNLQNAVIATEDRSFYKNDGINYGRFFLAIVTAGRSGGGS
                     TITQQLAKNAYLSQDQTVERKAKEFFLALELSKKYSKEQILTMYLNNAYFGNGVWGVE
                     DASKKYFGVSASEVSLDQAATLAGMLKGPELYNPLNSVEDSTNRRDTVLQNMVAAGYI
                     DKNQETEAAEVDMASQLHDKYEGKISDYRYPSYFDAVVNEAVSKYNLTEEEIVNNGYR
                     IYTELDQNYQANMQIVYENTSLFPRAEDGTFAQSGSVALEPKTGGVRGVVGQVADNDK
                     TGFRNFNYATQSKRSPGSTIKPLVVYTPAVEAGWALNKQLDNHTMQYDSYKVDNYAGI
                     KTSREVPMYQALAESLNLPAVAAVNDLGVDKAFEAGEKFGLNMEKVDRVLGVALGSGV
                     ETNPLQMAQAYAAFANEGLMPEAHFISRIENASGQVIASHKNSQKRVIDKSVADKMTS
                     MMLGTFTNGTGISSSPADYIMAGKTGTTEAVFNPEYTSDQWVIAYTPDVVISHWLGFP
                     TTDENHYLAGSTSNGAAHVFRNIANTILPYTPGSTFTVENAYKQNGIAPANTKRQVQT
                     NDNSQTDDNLSDIRGRAQSLVDEASRAISDAKIKEKAQTIWDSIVNLFR"
     gene            5482..5634
                     /gene="rpmG"
                     /locus_tag="VQ540_001963"
     CDS             5482..5634
                     /gene="rpmG"
                     /locus_tag="VQ540_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HET2545716.1"
                     /translation="MALKKASLACAVCGSRNYSIKISGNPKPTRLEVNKFCKHCGKYT
                     THRETR"
     gene            5644..5820
                     /gene="secE"
                     /locus_tag="VQ540_001964"
     CDS             5644..5820
                     /gene="secE"
                     /locus_tag="VQ540_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HET2545717.1"
                     /translation="MRFIGDIFRLLKDTTWPTRKESWRDFRSIMEYTAFFVVIIYIFD
                     QLIVSGLIRFINIF"
     gene            5876..6412
                     /gene="nusG"
                     /locus_tag="VQ540_001965"
     CDS             5876..6412
                     /gene="nusG"
                     /locus_tag="VQ540_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000376740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HET2545718.1"
                     /translation="MDSFDKGWFVLQTYSGYENKVKENLLQRAQTYNMLDNILRVEIP
                     TQTVQVEKNGKRKEVEENRFPGYVLVEMVMTDEAWFVVRNTPNVTGFVGSHGNRSKPT
                     PLLEQEIRDILVSMGQTVQEFDFDVEIGQTVRIIDGAFADYTGKITEIDNNKVKMIIS
                     MFGNDTVAEVNLNQIAEL"
BASE COUNT         2015 a         1128 c         1418 g         1921 t
ORIGIN      
        1 atatatcacg gatacagttg ggaaagaagc tattaaacat ttggagagtc cttttgggat
       61 gaacatgtca aatattacta tagatgggca agaaatggat ctgagtcaaa cgatgccttc
      121 ttatgctcaa gtagtgagtc tttatgatga tacaagtatc tctgttagta gtaatgagac
      181 ggacaaagtg ttggctggct ccctctatac tgatacaaat gaacagggat taacgattcc
      241 aagcagttta ctaaaaaatt ggaatgaaca gacaggaaaa aatttgacag ctaatgatct
      301 tattggcaaa tcagtctcag ccagcattgt agaaagtgct gccgaaacta gtaagattgc
      361 tcaatttcaa acgaagattg tacgtgtaat caatgatgaa gatgacatgg aggacagcaa
      421 cagtttcatg ctgtctcatc aaatggaaac gattttgaaa gaggctggat ttacgaaagc
      481 tgtatcttat tttatcttgg aactcaaaga tccatcacag acaaaagtag taacagaaga
      541 attacagaaa aataagaagt atactgtgct ttctcaacag agagttcttg atattgtgat
      601 tatctttatt cgtgttattc agggattatt gattgtgctt tcatcacaag ctattgtggt
      661 agcagcggtt atgattggta tcattattta catcaatatc atgcagcgtt ccaaggaaat
      721 aggtgtcatg aaggcagttg gttatcagaa tcgtgatgtc aaaggaattt ttatttacga
      781 ggctatctgg attgtaggca tcgccttgct gctggcattt ttggttgcac aaggggtggg
      841 aagtttggcg aatgcgattg taagtcactt ttacccatcc atcactaaag tttttgaatt
      901 aaatctttta tctgttttag gaactctagt tttcgctcta ttacttggtt atgtctcagc
      961 ctacttcccg gcgcgtaaga ttagtaaaat ggatcctgta gaaccgttac gctatgaata
     1021 gtaagggatt ccttgattta cagtcttaaa aagaaactaa catagaaaaa caatggacat
     1081 acttgcaatt caactcaaat agttgtataa taggtttgtt gaaaggtgat ttgtagtgat
     1141 tcaagttact cttttcacaa taaaaatttc atgattttca taaggaggaa atcactaatg
     1201 gtagttaaag ttggtattaa cggtttcgga cgtatcggtc gtcttgcttt ccgtcgtatc
     1261 caaaacgtag aaggtgttga agttacacgc atcaacgacc ttacagatcc agttatgctt
     1321 gcacacttgt tgaaatacga cacaactcaa ggtcgtttcg acggtactgt tgaagttaaa
     1381 gaaggtggat ttgaagttaa cggtaaattc atcaaagttt ctgctgaacg tgatccagaa
     1441 caaatcgact gggctactga cggtgtagaa atcgttcttg aagctactgg tttctttgct
     1501 aagaaagaag cagctgaaaa acaccttaaa ggtggagcta aaaaagttgt tatcactgct
     1561 cctggtggaa acgacgttaa aacagttgta ttcaatacta accacgacgt tcttgacggt
     1621 actgaaacag ttatctcagg tgcttcatgt actacaaact gcttggctcc aatggctaaa
     1681 gctcttcaag acaactttgg tgttgttgaa ggattgatga ctactatcca cgcttacact
     1741 ggtgaccaaa tgatccttga cggaccacac cgtggtggtg accttcgccg tgctcgcgct
     1801 ggtgctgcaa acatcgttcc taactcaact ggtgctgcaa aagctatcgg tcttgtaatc
     1861 ccagaattga atggtaaact tgatggatct gcacaacgcg ttccaactcc aactggatca
     1921 gttactgaat tggtagcagt tcttgaaaag aacgttactg ttgatgaagt gaacgcagct
     1981 atgaaagcag cttcaaacga atcatacggt tacacagaag atccaatcgt atcttcagat
     2041 atcgtaggta tgtcttacgg ttcattgttt gacgcaactc aaactaaagt tcttgacgtt
     2101 gacggtaaac aattggttaa agttgtatca tggtacgaca acgaaatgtc atacactgca
     2161 caacttgttc gtactcttga atacttcgca aaaattgcta aataattctt gagttgatag
     2221 aaagcaaggc tttgtggtct tgctttttat atggaaaaat ggatgacacg atcatccatt
     2281 cttttttaat tctttttcaa atgtatttga aagggtagtg aaagttagct tctctaaagt
     2341 aagtgggtgg gtaaaggaaa gtcggaaggc atgaagcata agccgacttg tctttgattt
     2401 actattatag agagggtcgc ccaggatagg aagattatga tgcgaaaggt gcacacgaat
     2461 ctgatgggtt cgccctgtct ttagcttgca acgagccaag gaagtcttgt ttgagaattg
     2521 ctttaatctg cttacatacg tttcagcata ttgcccattt tttgcatcaa ctattctttt
     2581 tctacgatca tggcgatcac gtccaatttt gtctctgaaa acaagttctt ttctgttgat
     2641 atttccatca actagagccc aatattctct agaaatctct tttttctcca ataagcgatt
     2701 gagaatgggc aggataaaag gatttttggc aaagagaact aagccactgg tttccatgtc
     2761 cagacgatga acgacatagc aggtttggcc aacataggta ctgacatggt taagaagggc
     2821 aatttcgttt ggttgattac catgcgtttt catcccctct ggtttgttta caataatcaa
     2881 gtattgatct tgataaactt cctgcactaa gtctgggttg ccccaaggga tcgtcttttg
     2941 gggataatct tcctcgtcaa aagtcaactg gcaaacatct ccaggattta cgatttcgtt
     3001 ccagtggact tcttcttgat ttatcaaaat atgtttcttg attctcaaaa aatgacggat
     3061 ttttctaggg atgaggagtt gttcctcaag taattgcttt accgtcattt gaggtagaga
     3121 ggcgggtaat gtaaatgtga attgcataca gatattgtaa caaaaaaagc cctatttgga
     3181 taggaaatag ctaaattctt gtcttcctat gatgaagatg ataaaataaa cgcatgaaat
     3241 tagataaatt atttgagaaa tttctttctc tttttaaaaa agaaacaagt gaactagagg
     3301 actctgattc tactatctta cgtcgctctc gtagtgatcg aaaaaaatta gcccaagtag
     3361 gtccgattcg aaaattctgg cgtcgttatc atctaacaaa gattatcctt atactaggtt
     3421 tgagtgcagg cttgctagtt ggaatctatt tgtttgctgt agccaagtcg accaatgtca
     3481 atgatttgca aaatgccttg aaaactcgga ctcttatttt tgaccgtgaa gaaaaagagg
     3541 ctggtgcctt gtctggtcaa aagggaacct atgttgagct gactgatatc agtaaaaact
     3601 tgcagaatgc tgttattgcg acagaagacc gttctttcta taaaaatgac gggattaact
     3661 atggccgttt cttcttggct attgtcactg ctggacgttc aggtggtggc tctaccatta
     3721 cccaacagct ggctaaaaac gcctatttat cacaggatca aactgttgag agaaaagcga
     3781 aagaattttt ccttgcctta gaattaagca aaaaatatag taaggagcaa attctaacca
     3841 tgtaccttaa caacgcttat tttggaaatg gtgtgtgggg tgtagaagat gcgagtaaga
     3901 aatactttgg agtttctgca tcagaagtga gtctggatca agctgcgact ctggcaggga
     3961 tgctcaaggg gccggaactg tataatccct tgaattccgt agaagattct actaatcggc
     4021 gcgatactgt cttgcagaat atggttgcag caggatatat tgataaaaac caagaaaccg
     4081 aagctgctga agttgatatg gcttcgcaat tgcacgataa gtatgaagga aaaatctcag
     4141 attaccgtta cccctcttat tttgatgcgg tggttaatga agctgtttcc aagtataatc
     4201 taacagagga agagattgtc aataatggct accgcattta cacagagctg gaccaaaact
     4261 accaagcaaa tatgcagatt gtttatgaaa acacatcgct atttccgagg gcagaggatg
     4321 gaacgtttgc tcaatcagga agtgtagctc tcgaaccgaa aacaggggga gttcgtggag
     4381 ttgtcggtca agttgctgac aatgataaaa ctggattccg gaatttcaac tatgcaaccc
     4441 aatcaaagcg tagtcctggt tctacaatta agcctttagt tgtttatacg ccagcagttg
     4501 aagcaggctg ggctttgaat aagcagttgg ataaccatac catgcagtat gacagctata
     4561 aggttgataa ctatgcaggg atcaaaacga gtcgagaagt tcctatgtat caagccttgg
     4621 cagaatcgct taatctacct gctgttgccg ctgttaatga tttgggtgtc gacaaggctt
     4681 ttgaggcagg cgaaaaattc ggactcaaca tggaaaaggt cgaccgtgtt cttggtgtcg
     4741 ccttgggaag cggtgttgaa accaaccctc ttcaaatggc tcaagcatac gctgcctttg
     4801 caaatgaagg tttaatgcct gaagctcatt ttattagtag aattgaaaat gctagtggac
     4861 aagttattgc gagtcataaa aattcacaaa aacgggtgat tgataagtct gtagctgaca
     4921 agatgaccag tatgatgttg gggactttca ccaacggtac cggtattagt tcatcgcctg
     4981 cagactatat tatggcaggg aaaactggaa caactgaagc agttttcaat ccggagtaca
     5041 caagtgacca gtgggtaatt gcttatactc cggatgtagt gattagccac tggcttggct
     5101 ttcctaccac tgatgaaaat cactatctag ctggctctac ttcaaacggt gcagctcatg
     5161 tctttagaaa cattgccaat accattttac cttatacgcc aggaagtacc tttacggttg
     5221 aaaatgctta taagcaaaat ggaattgcac cagccaatac aaaaagacaa gtacaaacca
     5281 atgataatag ccagacagat gataatttgt ctgatattcg agggcgtgcg caaagtctag
     5341 tagatgaggc tagccgggct atctcagatg cgaagattaa ggaaaaggct caaacaatat
     5401 gggattcgat agtcaatcta tttcgctaag atgcttgtca aagcctagct ttcttgttat
     5461 aatggatagg atggaggcgt tatggcacta aaaaaagcaa gcctagcttg tgcggtttgt
     5521 ggttcgagaa actattcaat caagatcagc ggaaacccca agcctacacg actagaagta
     5581 aataaatttt gtaagcattg tggcaagtac actacacaca gagaaacgag ataggagaga
     5641 gcgatgcgtt ttattggaga tatttttaga cttcttaaag acacaacgtg gccaactcgc
     5701 aaggaaagct ggagagattt tcgttctatc atggaataca cagctttctt tgtagtaatt
     5761 atttacattt ttgaccagtt gattgtttca ggtttgattc gatttattaa cattttttag
     5821 aagattagtg gagttaatta cactagaaat cttctatatt atgaaaggaa atatcatgga
     5881 tagttttgat aaagggtggt ttgttttaca aacttattct ggttatgaaa ataaggtgaa
     5941 agaaaatcta ttacaacgtg cacaaaccta caatatgttg gataatattc tacgcgttga
     6001 aattccaaca caaacagtgc aagttgaaaa aaatggaaag agaaaagaag tagaagaaaa
     6061 tcgctttcca ggttatgttc ttgtagaaat ggtcatgaca gatgaagctt ggtttgttgt
     6121 tcgaaacaca ccaaatgtta caggatttgt cggatcacac gggaacagat caaaaccaac
     6181 tccattattg gaacaagaaa ttcgtgacat tttggtatct atgggacaaa ctgttcaaga
     6241 atttgatttc gatgttgaga ttggtcaaac tgtacgtatt attgatggtg cttttgcaga
     6301 ctacactggt aagattacag aaattgataa taacaaagtg aaaatgatta tctctatgtt
     6361 tggtaatgac acagttgcag aagtaaacct aaaccaaatc gcagaattat aaccctgaga
     6421 gaggctggag cctctctttt ttgtgcagtt taggagctaa agggaacaga atggagaaaa
     6481 tg
//
LOCUS       DAVBDR010000083         6447 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.083, whole genome shotgun sequence.
ACCESSION   DAVBDR010000083 DAVBDR010000000
VERSION     DAVBDR010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6447)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6447)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6447
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.083"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            222..422
                     /locus_tag="VQ540_001966"
     CDS             222..422
                     /locus_tag="VQ540_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000226586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2545719.1"
                     /translation="MVASASASSTSTQAQEQVDKSELRALSQELDQRLKALATVSDPK
                     IDATKAVLLDAQKAPEDSALTE"
     gene            447..863
                     /locus_tag="VQ540_001967"
     CDS             447..863
                     /locus_tag="VQ540_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2545720.1"
                     /translation="MKAALDSLKDVKANASDSKPAQDKKDAKQGTEDSKDSDKMTETN
                     SVPAGVIVVSLLALLGVIAFWLIRRKKESEIQQLSTELIKVLGQLDAEKADKKVLAKA
                     QNLLQETLDFVKEENGSAETETKLVEELKAILDKLK"
     gene            1094..1801
                     /gene="ccdA2"
                     /locus_tag="VQ540_001968"
     CDS             1094..1801
                     /gene="ccdA2"
                     /locus_tag="VQ540_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004237834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HET2545721.1"
                     /translation="METIVFLISVFLAGVLSFFSPCIFPLLPVYAGILLDDQESAKSF
                     SLFGRKVLWSGLIRTLCFIAGISLIFFILGFGAGYFGHILYANWFRYVMGAIIIILGL
                     HQMEIFHLKKLEVQKSFTFKKSDSNRYWSAFLLGITFSFGWTPCIGPVLSSVLALAAS
                     GGNGAWQGAIYTLIYTLGMALPFLVLALASGLVMPYFSKIKRHMMLLKKIGGFLIVLM
                     GILLLLGQVNVLAGIFE"
     gene            1812..2369
                     /gene="sdbB"
                     /locus_tag="VQ540_001969"
     CDS             1812..2369
                     /gene="sdbB"
                     /locus_tag="VQ540_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     lipoprotein SdbB"
                     /protein_id="HET2545722.1"
                     /translation="MKKVMFAGLSLLSLVVLMACGEEETKKTQAAQQPKQQTTVQQIA
                     VGKDAPDFTLQSMDGKEVKLSDFKGKKVYLKFWASWCGPCKKSMPELMELAAKPDRDF
                     EILTVIAPGIQGEKTVEQFPQWFQEQGYKDIPVLYDTKATTFQAYQIRSIPTEYLIDS
                     QGKIGKIQFGAISNADAEAAFKEMN"
     gene            2490..3881
                     /locus_tag="VQ540_001970"
     CDS             2490..3881
                     /locus_tag="VQ540_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001020339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HET2545723.1"
                     /translation="MNIFRTKNVSLDKTEMHRHLKLWDLILLGIGAMVGTGVFTITGT
                     AAATLAGPALVISIVISALCVGLSALFFAEFASRVPATGGAYSYLYAILGEFPSWLAG
                     WLTMMEFMTAISGVASGWAAYFKGLLSQYGIAFPQALNGTFNPQAGTFVDLLPILVLV
                     LVTSLVLLNAKAALRFNSILVILKFSALALFVLVGIWNIKFDNWSNFAPYGFGQIYGA
                     STGIMAGASLMFFGFLGFESISMAVDEVKTPQKNIPRGIVLSLSIVTILYALVTLVLT
                     GVVHYSHLNVDDAVAFALRSVGISWAANYVSLVAILTLITVCISMTYALSRMIYSLAR
                     DGLVPAAFKELTKTSKIPKNATILTGLASAVAAGMFPLASIAAFLNICTLAYLIMLAY
                     GLIRLRKEKGMPKAGEFKTPLVPLLPILSIIICLSFMLQYNMNTWIAFLVALLVGSII
                     YFTYGYKHSTIEE"
     gene            4024..4941
                     /gene="adcAII"
                     /locus_tag="VQ540_001971"
     CDS             4024..4941
                     /gene="adcAII"
                     /locus_tag="VQ540_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding lipoprotein AdcAII"
                     /protein_id="HET2545724.1"
                     /translation="MKKQNLFLVLLSVFLLCLGACGQKESQTGKGMKIVTSFYPIYAM
                     VKEVSGDLNDVRMIQSSSGIHSFEPSANDIAAIYDADVFVYHSHTLESWAGSLDPNLK
                     KSKVKVLEASEGMTLERVPGLEDVEAGDGVDEKTLYDPHTWLDPEKAGEEAQIIADKL
                     SEVDSEHKETYQKNAQAFIKKAQELTKKFQPKFEKATQKTFVTQHTAFSYLAKRFGLN
                     QLGIAGISPEQEPSPRQLTEIQEFVKTYKVKTIFTESNASSKVAETLVKSTGVGLKTL
                     NPLESDPQNDKTYLENLEENMSILAEELK"
     gene            4949..>6447
                     /locus_tag="VQ540_001972"
     CDS             4949..>6447
                     /locus_tag="VQ540_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HET2545725.1"
                     /translation="MKINKKYLAGSVAVLALSVCSYELGRHQAGQVKKESNRVSYIDG
                     DQAGQKAENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIISE
                     ELLMKDPNYQLKDSDIVNEIKGGYVIKVDGKYYVYLKDAAHADNIRTKEEIKRQKQER
                     SHNHNSRADNAVAAARAQGRYTTDDGYIFNASDIIEDTGDAYIVPHGNHFHYIPKSDL
                     SASELAAAQAYWNGKQGSRPSSSSSHNANPAQPRLSENHNLTVTPTYHQNQGENISSL
                     LRELYAKPLSERHVESDGLVFDPAQITYRTVNGVAVPHGDHYHFIPYSQLSPLEEKLA
                     RMIAVKGQNGAVLPGMHYLKPAPKPQVQPSTEKKQTDFAVEQVVRKVGEGYVVEIAGV
                     SHYVFAKDLAKDKIDAIENLLSKKTQETHALVAKKENVAPRDQEFYDKAYNLLTQAHK
                     VLSENKGRTSDFQALDKLAERLNNESSNKVKLVDDLLAFLAPITHPERLG"
BASE COUNT         1980 a         1172 c         1354 g         1941 t
ORIGIN      
        1 atggtttcag aaatttctct taccaacatt aaccacacca tcggttatta tagtaaaatg
       61 gaataagaac aggacaaatc gatcaggaca gtaaaatcga attctaacaa tgttttagaa
      121 gtctatatgt actattctag tttcaatata ccataactgc tcctagtcaa cctgcaagtc
      181 ctgtcccagc tccaagctca gctccgactc aagatcctag agtggtagca agcgcttcgg
      241 ctagctcaac gagcacacaa gctcaagagc aagttgacaa gtctgaactt cgtgccttga
      301 gtcaagagtt agaccaacgc ttgaaagctt tggcaacagt atctgatcca aaaatcgatg
      361 caaccaaggc tgtcctccta gatgctcaaa aagctccgga agatagtgcc ttgacagagt
      421 aaggtctgca tactgcagta gagtctgtga aggctgcctt ggactctctc aaagatgtga
      481 aagcaaatgc tagcgacagc aagcctgcac aggacaagaa ggatgcaaaa caaggaacgg
      541 aagatagtaa ggattcagat aagatgactg aaacaaactc agttccggca ggagtgattg
      601 tggtcagtct acttgccctc ctaggcgtga ttgccttctg gctgattcgc cgtaagaaag
      661 agtcagaaat ccagcaatta agcacggaat tgatcaaggt tctaggacag ctagatgcag
      721 aaaaagcgga taaaaaagtc cttgccaaag cccaaaacct tctccaagaa acccttgatt
      781 tcgtgaaaga agaaaatggc tcagcagaga cagaaactaa actagtagag gagcttaaag
      841 caatccttga caaactcaag taaaacatga tttatgaaat gtcagaccta aaagacattt
      901 tcgttcacaa aagcagtgac gagtaatcct tgtcgttgct ttttggctat tttgggggat
      961 aagatccgcc ttgactagca aaagaaaaga ttggtccaat agtgcccgat acgattttgc
     1021 gtagcagaaa gcttacaaat aaaattgaat atagtaaaat aggattagaa ttattaagaa
     1081 agttggttct ttattggaaa cgatagtatt tttaatctct gtttttctag caggtgtttt
     1141 atcctttttt tctccttgta tttttcctct tctgccagtc tatgctggga ttttattgga
     1201 tgatcaagaa agtgcaaaaa gcttttcttt gtttgggaga aaggttctct ggtcaggctt
     1261 gattcgaaca ctttgcttta tcgctggtat ctctctcatt ttctttattc taggctttgg
     1321 tgctggttac tttggtcata ttctctatgc aaattggttt cgatatgtca tgggagctat
     1381 tattatcatt ttgggtcttc accagatgga aatttttcat ttgaagaaat tagaagttca
     1441 aaaaagtttt acctttaaaa aatcagattc taatcgttat tggtcagctt ttttacttgg
     1501 tattaccttt agctttggtt ggacaccttg tattggtcca gttttaagtt ctgttttagc
     1561 acttgcggct tctggaggca atggtgcttg gcaaggagcg atttatactc tcatttacac
     1621 tctgggcatg gcccttcctt tcttggtctt ggcactagct tcaggtctag tcatgccata
     1681 ttttagtaaa atcaagcgtc atatgatgct actaaagaaa attggtggtt tcctcattgt
     1741 tttaatggga attttgttac tattaggaca agtaaatgtt ctagctggaa tttttgaata
     1801 aaggaggaca aatgaaaaaa gtaatgtttg ctggcttaag tctcttgtca ttagttgtat
     1861 tgatggcctg tggtgaggaa gaaactaaaa agactcaagc agcacaacag ccaaaacaac
     1921 aaacgactgt acaacaaatt gctgttggaa aagatgctcc agacttcaca ttgcaatcca
     1981 tggatggcaa agaagttaag ttatctgatt ttaagggtaa aaaggtttac ttgaagtttt
     2041 gggcttcatg gtgtggtcca tgcaagaaaa gtatgccaga gttgatggaa ctagcggcga
     2101 aaccagatcg tgatttcgaa attcttactg tcattgcacc aggaattcaa ggtgaaaaaa
     2161 ctgttgagca attcccacaa tggttccagg aacaaggata taaggatatc ccagttcttt
     2221 atgataccaa agcaaccacc ttccaagctt atcaaattcg aagcattcct acagaatatt
     2281 taattgatag ccaaggaaag attggaaaga ttcaatttgg tgctatcagt aatgcggatg
     2341 cagaagcagc atttaaagaa atgaactaga atcgataaaa tctgattaca agatgtagtc
     2401 agattttttt agaaaaacat tttataaata ttcacatatc tcctatattt atggtaaaat
     2461 agaattatca gtttattttg gagtcaaaga tgaatatatt tagaacaaag aatgttagtt
     2521 tagataaaac agagatgcat aggcatttga agttatggga tttgattttg ctgggtatcg
     2581 gagccatggt agggacaggc gtctttacaa tcacaggtac tgcagctgca acacttgctg
     2641 gcccagccct agtgatttca atcgttattt ctgccttgtg tgtgggatta tcagccctct
     2701 tttttgcaga atttgcctcg cgagtacccg ctacaggagg tgcctatagt tacctctatg
     2761 ctatcttagg agaattccct tcctggttgg ctggttggtt aaccatgatg gagttcatga
     2821 cagccatatc aggcgtagct tcgggttggg cagcttattt taaaggcttg ctctctcaat
     2881 acgggatagc ctttcctcag gctttaaatg gtacctttaa tcctcaagca gggacatttg
     2941 ttgatttatt gcctattctt gtcttggtct tggtgacttc gcttgtttta ctaaatgcca
     3001 aggcagcctt acgctttaat tcgattctag ttattttgaa attttccgct ttagctctct
     3061 ttgttttagt aggaatttgg aatattaagt ttgataattg gagcaatttt gctccttacg
     3121 gttttggaca aatctatgga gctagcactg gtattatggc tggtgcgtcc ttgatgttct
     3181 tcggtttttt gggatttgaa tccatctcta tggctgtaga tgaagtcaag actcctcaaa
     3241 aaaatattcc tagagggatt gtcttatcgc tttctatcgt aaccattctc tatgccttgg
     3301 tgacccttgt tttgactggt gtggttcact atagtcattt aaatgtcgat gatgccgttg
     3361 cctttgccct tcgtagtgtt gggattagtt gggcagccaa ctatgtgtca ttagtggcta
     3421 tcttgacctt gattacagtt tgtatttcga tgacctatgc cctatcgcgt atgatttaca
     3481 gtttagcacg tgacggctta gtgcctgctg cctttaagga actgacgaag actagcaaga
     3541 taccaaagaa tgctactatc ttgacaggtc tagcttcagc agtagcagca ggaatgttcc
     3601 cactagccag tattgcagcc tttttaaata tttgtacctt agcctacttg atcatgctgg
     3661 cttatggtct gattcgctta cggaaagaaa aaggaatgcc caaagctggg gaatttaaaa
     3721 caccattggt acctctgtta ccaattttat cgatcatcat ttgtttatcc ttcatgttac
     3781 agtataatat gaacacctgg attgctttcc tagttgcgtt gttagtagga agtattattt
     3841 acttcactta tggctataag cattctacca tagaagaata aagtgaaagt ctattgagtt
     3901 gttgacactc agtagatttt tatatgtgaa agaaatttca aattttttct aaaaatatct
     3961 tgacagatta aattttcagg agtagaatat ttactagtta attaaatggt taaggagttg
     4021 ttcatgaaga aacaaaattt atttttagtc ctgttaagtg tctttctttt gtgtttgggg
     4081 gcttgtggtc aaaaggaaag tcagacagga aaggggatga aaattgtgac cagtttttat
     4141 cctatctacg ctatggttaa ggaagtatct ggtgacttga atgatgttcg gatgattcag
     4201 tcaagtagtg ggattcactc ctttgaacct tcggcaaatg atatcgcagc catctatgat
     4261 gcagatgtct ttgtttacca ttctcataca ctcgaatctt gggcaggaag tctggatcca
     4321 aatctaaaaa aatccaaagt gaaggtctta gaggcttctg agggaatgac cttggaacgt
     4381 gtccctggac tagaggatgt ggaagcaggg gatggagttg atgaaaaaac gctctatgac
     4441 cctcacacat ggctagatcc tgaaaaagct ggagaagaag cccaaattat cgctgataaa
     4501 ctttcagagg tggatagtga gcataaagag acttatcaaa aaaatgcgca agcctttatc
     4561 aaaaaagctc aggaattgac taagaaattc caaccaaaat ttgaaaaagc gactcagaaa
     4621 acatttgtaa cacaacatac agccttttct tatctagcga agagatttgg gcttaatcaa
     4681 cttggtattg caggtatctc tcctgaacaa gaaccaagtc cacgacaact aacagaaatt
     4741 caggaatttg ttaagaccta taaggttaaa acgattttta cagaaagtaa cgcttcttca
     4801 aaagtagctg aaactcttgt caaatcaaca ggtgtgggtc ttaaaactct gaatccttta
     4861 gagtcagacc cacaaaatga caagacctat ttagaaaatc ttgaagaaaa tatgagtatt
     4921 ctagcagaag aattaaagtg aggaaagaat gaaaatcaat aaaaaatatc tagcaggttc
     4981 agtggcagtc cttgccctaa gtgtttgttc ctatgaactt ggtcgtcacc aagctggtca
     5041 ggttaagaaa gagtctaatc gagtttctta tatagatggt gatcaggctg gtcaaaaggc
     5101 agaaaatttg acaccagatg aagtcagtaa gagagagggg atcaacgccg aacaaattgt
     5161 tatcaagatt acggatcaag gttatgtgac ctctcatgga gaccattatc attactataa
     5221 tggcaaggtt ccttatgatg ccatcatcag tgaagaactt ctcatgaaag atccgaatta
     5281 tcagttgaag gattcagaca ttgtcaatga aatcaagggt ggctatgtga ttaaggtaga
     5341 cggaaaatac tatgtttacc ttaaagatgc agcccatgcg gacaatattc ggacaaaaga
     5401 agagattaaa cgtcagaagc aggaacgcag tcataatcac aactcaagag cagataatgc
     5461 tgttgctgca gccagagccc aaggacgtta tacaacggat gatgggtata tcttcaatgc
     5521 atctgatatc attgaggaca cgggtgatgc ttatattgtc cctcacggca atcacttcca
     5581 ctatattcct aagagtgatt tgtctgccag tgaattagct gctgcccaag cctattggaa
     5641 tgggaagcag ggatctcgtc cttcttcaag ttctagtcat aatgcaaatc cagctcaacc
     5701 aagattgtca gagaaccaca atctgactgt cactccaact tatcatcaaa atcaagggga
     5761 aaacatttca agccttttac gtgaattgta tgctaaaccc ttatcagaac gccatgtaga
     5821 atctgatggc ctagtatttg atccggcaca aataacatat cgtacagtca atggtgttgc
     5881 tgtaccgcac ggagaccatt atcactttat tccttattca caactgtcac ctttggaaga
     5941 aaaattggct cgtatgattg ctgttaaggg acaaaatggt gcagtcttgc caggaatgca
     6001 ttatttgaaa ccagcaccaa aaccgcaagt tcaaccatca actgagaaaa aacaaactga
     6061 ttttgcagta gaacaggttg ttagaaaagt tggagaaggc tatgttgtgg aaattgctgg
     6121 tgtcagtcac tatgtttttg ctaaagactt ggctaaggat aagattgatg ctattgaaaa
     6181 tctcttgtct aagaaaactc aagagacaca tgctctagtt gctaaaaaag aaaatgtcgc
     6241 tcctcgtgac caagaatttt atgataaagc ttacaatctg ttaacccagg ctcataaagt
     6301 cttgtctgaa aataaaggtc gtacttctga tttccaagcc ttagacaaat tagcagaacg
     6361 cttgaataat gaatcttcta ataaagtaaa attggtagat gatttattgg cattcctagc
     6421 accaattacc cacccagaac gccttgg
//
LOCUS       DAVBDR010000084         6187 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.084, whole genome shotgun sequence.
ACCESSION   DAVBDR010000084 DAVBDR010000000
VERSION     DAVBDR010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6187)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6187)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6187
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.084"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            complement(119..751)
                     /locus_tag="VQ540_001973"
     CDS             complement(119..751)
                     /locus_tag="VQ540_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000200889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HET2545726.1"
                     /translation="MTSITAIFFDLDGTLVDSSIGIHNAFTYTFKELGVPSPDAKTIR
                     GFMGPPLESSFATCLSKDQISEAMQIYRSYYKAKGIYEAQLFPQIIDLLEELSSSYPL
                     YITTTKNTSTAQDMAKNLEIHHFFDGIYGSSPEAPHKADVIHQALQTHQLAPEQAIII
                     GDTKFDMLGARETGIQKLAVTWGFGEQADLLNYQPDYIAHKPLEVLAYFQ"
     gene            complement(773..1645)
                     /gene="sdaAA"
                     /locus_tag="VQ540_001974"
     CDS             complement(773..1645)
                     /gene="sdaAA"
                     /locus_tag="VQ540_001974"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HET2545727.1"
                     /translation="MFYSIKELVEQADLDFQGNVAELMITTEFELTGREREEVFLLME
                     RNLEVMKASVQLGLNENKSRSGLTGGDAAKLDHYIKNEKTLSDYTILSAARNAIAVNE
                     HNAKMGLVCATPTAGSAGCLPSVLTAAIEKLDLSHEQQLDFLFAAGAFGLVIANNASI
                     SGAEGGCQAEVGSASAMSAAALTLAAGGTPYQASQAIAFVIKNMLGLICDPVAGLVEV
                     PCVKRNAMGASFAFIAADMALAGIESKIPVDEVIDAMYQVGASMPTAFRETAEGGLAT
                     TPTGRRLQKEIFGE"
     gene            complement(1654..2325)
                     /gene="sdaAB"
                     /locus_tag="VQ540_001975"
     CDS             complement(1654..2325)
                     /gene="sdaAB"
                     /locus_tag="VQ540_001975"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015606087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HET2545728.1"
                     /translation="MKSLRFQSVFDIIGPVMIGPSSSHTAGAVRIGKIVSSIFDDTPT
                     EVEFQLFNSFAKTYRGHGTDLALVAGILGMDTDDPEIPNSLEIAHKRGIKIVWTIQKD
                     SNAPHPNTTKITVKNAHKTISVTGISIGGGNIQVTELNGFAVSLNMNTPTIIIVHQDI
                     PGMIALVTEALSRYGINIAQMNVTREKAGEKAIMIIEVDSRNCDEAIEEIRKIPHLHN
                     VNFFK"
     gene            2567..3139
                     /locus_tag="VQ540_001976"
     CDS             2567..3139
                     /locus_tag="VQ540_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HET2545729.1"
                     /translation="MKSITKKIKATLAGVAALFAVFSPSFVSAQESSTYTVKEGDTLS
                     EIAETHNTTVEKLAENNHIDNIHLIYVDQELVIDGPVAPVATPAPATYAAPAAQDETV
                     SAPVVSETVVSTVSGSEAEAKEWIAQKESGGSYTATNGRYIGRYQLTDSYLNGDYSAE
                     NQERVADAYVAGRYGSWTAAKNFWLNNGWY"
     gene            complement(3191..4054)
                     /locus_tag="VQ540_001977"
     CDS             complement(3191..4054)
                     /locus_tag="VQ540_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001268160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET2545730.1"
                     /translation="MRYDFGKVYKEIRESKGLTQEEVCGGVLSRTSLSKIESGKTTPK
                     YENMEFLLRQINMSFEEFEYICQLYQPSQRTEIMQTYLNMRSIIGTSDLVNLFQKCQD
                     YLKTHHDLPIEEIRDMLEVVIYLRQHGAGELSKHAEQVVKKLWKKIEKQDTWYESDLK
                     ILNTILFSFPIEYLHLITGKILQRLEVYKNYQHLYDLRMTILLNLSTLYLYNQDKNMC
                     KQICYTLLEDAKNKKSYDRLAICYVRIGICTDDSKLIQKGFSLLELTEETSMLSHLKK
                     EVEIYYQAKER"
     gene            4520..4858
                     /locus_tag="VQ540_001978"
     CDS             4520..4858
                     /locus_tag="VQ540_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase C39"
                     /protein_id="HET2545731.1"
                     /translation="MLKKYPCTMQHDQSDCAAAVVSTVLLSYKKELSIMKIREIIGTD
                     MYGTTVSGIVSGLNKLNFTVKAVRVALEDLTPKLTFPAILQVKNDLGQNHFVVLHSIK
                     EKINGTRITK"
     gene            4836..5195
                     /locus_tag="VQ540_001979"
     CDS             4836..5195
                     /locus_tag="VQ540_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2545732.1"
                     /translation="MELVLPNNYVVIDEEEMMYLDGGAIYIPRWAITGAITGAAYAAL
                     AAAGGGGLQLVLASYGLRSALVAGIVKGLGVLGIHIGNAFANTVIRSIASAGIGAGAD
                     WILPILLMAGMGDVIIN"
     gene            5214..5426
                     /locus_tag="VQ540_001980"
     CDS             5214..5426
                     /locus_tag="VQ540_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000989850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2545733.1"
                     /translation="MMVVLISVIVAFLYHKITEYVNNRKIDIVIFLSLLISHFIWNYY
                     FLPIEILIAISGANLLLSFLKKLQIK"
     gene            5841..5909
                     /locus_tag="VQ540_001981"
                     /pseudo
     CDS             5841..5909
                     /locus_tag="VQ540_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424474.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
     gene            5889..>6187
                     /locus_tag="VQ540_001982"
     CDS             5889..>6187
                     /locus_tag="VQ540_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HET2545734.1"
                     /translation="MMYLDGGGVGCNWWNKRDNIAAAAVSGGMSVYQTYAIKKLIANR
                     GMMSRVVRSAITRYIGGVSMATITNALNIAATVAEVFSLGGAIAYGLDIVDGKFDG"
BASE COUNT         1901 a         1050 c         1311 g         1925 t
ORIGIN      
        1 atctacaacc ttaaaacagt gttttgagca gcccgcagct agtttcctag tttgctcttt
       61 gattttcatt gagtattact tcattttctt ctgaaataga gttgtcgccc agtctatgct
      121 attgaaaata cgccaaaact tctaagggtt tgtgagcgat ataatcaggt tgatagttta
      181 gtagatctgc ttgctctcca aatccccaag tgacggccaa tttctgaata cctgtttctc
      241 gagctcccag catatcaaac ttggtatctc cgatgatgat ggcttgttct ggtgctagtt
      301 gatgtgtctg taaggcttgg tgaatgacat ctgccttatg gggtgcttca gggctagaac
      361 cataaatacc atcaaagaaa tgatggattt ccaagttttt ggccatgtct tgagcagtag
      421 atgtattctt tgtcgtggtg atgtagagtg gataactgct cgataactcc tcaagcaagt
      481 ctataatctg aggaaagagt tgagcttcat agatgccttt tgccttatag taagaacgat
      541 atatctgcat ggcttcagaa atttggtctt tggacaggca ggtcgcaaaa ctactttcga
      601 gaggtggtcc cataaaacca cgaatagttt tggcatcagg gctaggcacc cccagctctt
      661 taaaggtata ggtaaaggca ttgtgaatcc cgatagaact atcaacgagg gttccatcca
      721 aatcgaaaaa aatcgctgtg atagaggtca tggtttctcc tatttgataa gcttattctc
      781 cgaaaatctc tttttggagg cgacgaccag taggggtggt agcgagtcca ccttcagctg
      841 tttcacgaaa ggcagttggc atgcttgctc ctacttggta catggcatcg atcacttcat
      901 ccacagggat tttagattcg atacctgcca aggccatgtc tgctgcgatg aaagcaaagc
      961 tagctcccat ggcattacgt ttgacacagg gaacttcgac caaacctgca acagggtcac
     1021 agatgaggcc tagcatattt ttaatgacaa aggcaatagc ttgactggcc tgataaggtg
     1081 ttccacctgc agccagagtc aaggcggcag cactcatagc agaggctgaa ccaacttcag
     1141 cttgacaccc accctcagca cctgagatgg aggcattgtt tgcgatgact agtccaaagg
     1201 caccagcagc aaagaggaaa tccaattgtt gctcgtggct gaggtctaat ttttcaatag
     1261 cagcagtgag aacggaaggg agacaaccgg cacttcctgc ggtaggagta gcgcagacca
     1321 agcccatttt agcattgtgt tcattgactg cgatagcatt tcgggcagca gagagaatcg
     1381 tgtaatctga taaagttttt tcgtttttga tgtagtgatc caatttggca gcatctccac
     1441 ctgtcaggcc actacgagat ttattttcat tgaggccaag ttggacagag gctttcataa
     1501 cttccagatt gcgttccatg agaaggaaga cttcttcacg ttcgcgaccg gtcaattcaa
     1561 actctgttgt aatcatgagt tctgcgacat ttccttgaaa gtccagatct gcttgctcga
     1621 ccaattcttt gatagaataa aacatgcttc ctcctattta aagaaattga cattgtggag
     1681 atgagggatt tttcgaattt cttcgatagc ctcatcacag ttgcgactgt caacttcgat
     1741 aatcataatg gctttttcac cagctttttc acgagtgaca ttcatctggg cgatattgat
     1801 accatagcgg gaaagcgcct ctgtaacaag ggcaatcata cctggaatat cttgatgaac
     1861 gatgatgata gtcggtgtat tcatattgag agagacggca aaaccattga gttcggttac
     1921 ctgaatattt cctccaccga tagaaatacc agtcacgctg atggtcttgt gggcattttt
     1981 aacagtaatt ttagtggtgt tagggtgagg ggcattgctg tctttctgaa tggtccagac
     2041 aatcttgata ccacgcttgt gggcaatttc cagactattt ggaatttcag gatcatctgt
     2101 atccattcct aaaatacctg caacaagggc taggtctgtt ccgtgaccac gataggtctt
     2161 ggcaaatgag ttaaaaagtt ggaattcaac ttctgtcgga gtatcatcaa aaatggaaga
     2221 gacaatcttc ccaatacgaa cagcaccagc ggtatggcta ctagatgggc caatcataac
     2281 tggtccgatg atatcaaaga cagattgaaa acgaagtgat ttcatcagtt tccccttata
     2341 aaaattctta tctctattat atcaaagaat gaggggcttg gctttaattg tggatgaaaa
     2401 cctttctaat acctcaaata gcataaaaat agtatctttt atgacaaaaa acaccttatt
     2461 tagggaaata aaaaataatt ttgtaatatt tctacataaa agtgtcaaga aacagtaata
     2521 tttaaagggt atgatagaac tatagaaaga aggagaattt tcgaatatga aatcaataac
     2581 taaaaagatt aaagcaactc ttgcaggagt agctgccttg tttgcagtat tttctccatc
     2641 atttgtatct gctcaagaat catcaactta cactgttaaa gaaggtgata cactttcaga
     2701 aatcgctgaa actcacaaca caacagttga aaaattggca gaaaacaacc acattgataa
     2761 cattcatttg atttatgttg atcaagagtt ggttatcgat ggccctgtag cgcctgttgc
     2821 aacaccagcg ccagctactt atgcggcacc agccgctcaa gatgaaactg tttcagctcc
     2881 agtagtaagt gaaacagttg tttcaactgt aagcggatct gaagcagaag ccaaagaatg
     2941 gatcgctcaa aaagaatcag gtggtagcta tacagctaca aatggacgtt atatcggacg
     3001 ttaccaatta acagattcat acctgaacgg tgactactca gctgaaaacc aagaacgtgt
     3061 agcagatgcc tacgttgcag gacgttacgg ttcatggact gctgctaaaa acttctggct
     3121 taacaatggc tggtattaag aactaacgaa caaataatat gtaaagagtc gaggaaatcc
     3181 ctcggctttt ttatctttcc ttcgcttggt aatagatctc tacttctttt ttgagatgag
     3241 acagcataga agtttcctcg gttagctcca gaagggagaa ccctttttgg ataagtttag
     3301 aatcgtctgt acaaatccca atacggacat agcagatagc cagcctatcg tagcttttct
     3361 tattcttggc gtcctccagt aaagtgtagc agatttgctt acacatgttt ttatcttgat
     3421 tgtatagata gagtgtggaa aggtttaata gaattgtcat tcgcaagtca tataaatgtt
     3481 gatagttttt atagacttct aggcgttgca atatttttcc agtgatgaga tggaggtatt
     3541 caatgggaaa actgaaaaga atggtattga ggatttttag atcactctca taccatgtat
     3601 cttgtttttc aatttttttc caaagttttt tgacaacctg ttctgcgtgt tttgatagtt
     3661 cccctgcccc gtgttgacgg agataaataa caacttcaag catatctctg atttcttcta
     3721 tagggagatc gtggtgggtc ttgaggtagt cttggcattt ttgaaataaa ttgacaagat
     3781 cgctggtccc gataatggaa cgcatattga gataggtttg cataatctct gtgcgttgac
     3841 ttggttgata aagttgacag atatattcaa actcttcaaa actcatattg atttgacgga
     3901 gaagaaattc catattttca tattttgggg ttgtcttgcc actttcgatt tttgataagc
     3961 tggttcttga gagaacaccc ccacagacct cttcttgggt cagccccttt gactcacgta
     4021 tttctttata gacctttccg aaatcataac gcatgatttt ctcctttctg tgaaaaaagt
     4081 taacaaacaa taaaattttg ttaaaaatat tgtatcatag caatgtaaaa agtaaaaaag
     4141 aaagtcgaaa taaatttgtg aaaaaagtta acgtaatttt aaaatgagct taataagagg
     4201 tatgatgtag gtagaaaata aagataggag aaaaagtatg aataaaaaaa tattttgtat
     4261 tctagtatgt attatatcat tgattagtct ggccataatc tttccatggg gctggtcgat
     4321 ataatgtaag ggagcttgag ttgttaaagg aggcttagtc cttggacaaa aatctgctgt
     4381 actacaatgc ttggaaagat atcaagaaca aagaatgata cgattgaaaa taaactgatt
     4441 caagaactac tgggcagtga ttgaggtttg ggtgacatca aagaaaagtt agattaattc
     4501 taaagaattg agtatttcta tgttaaaaaa atatccttgt acgatgcaac atgatcagtc
     4561 agattgtgct gcggcagttg tttcaacagt tcttttatct tacaaaaagg aactatcaat
     4621 catgaagatt cgggaaatta ttggtacaga catgtatgga acgactgtca gtggtattgt
     4681 ttcaggtctg aataagttga attttacagt aaaagctgtt cgagtagcac tggaagattt
     4741 gactccaaaa ttaacatttc ctgcgattct tcaagttaag aatgatttag gtcaaaatca
     4801 ttttgtggta ttacatagta taaaggagaa aataaatgga actcgtatta ccaaataatt
     4861 atgttgtgat tgatgaagaa gagatgatgt accttgatgg gggggctata tatataccca
     4921 ggtgggcaat tacaggagcc attactggtg cagcatatgc agcattagca gcagcaggag
     4981 gtggaggcct tcaactagtt cttgcatctt atggattacg ctccgcactg gtagctggga
     5041 ttgttaaagg tttaggagta ttaggaattc atattggaaa tgcttttgca aatactgtta
     5101 ttagaagtat tgcatctgct ggaattggtg ctggagctga ttggatttta ccaatattat
     5161 tgatggctgg gatgggcgac gtgataatca attgagaata ggataatagt attatgatgg
     5221 ttgttttaat ttcagttatt gttgcattcc tgtaccataa aattacagag tatgtcaaca
     5281 acaggaaaat tgatattgtt atttttctat cattgctgat ttctcatttt atttggaatt
     5341 actatttttt accaattgaa atattgatag caatcagtgg agcaaattta ttattaagtt
     5401 ttttaaaaaa attacagatt aaataatatt attccatatg acatatcaac taggtcatta
     5461 gattttattg aagatataaa ttaaaaacga ggttgggaaa aaactcaatt tgaaagtgaa
     5521 attgagtaaa tttttctatt atataacgca tattatcaag atttttgaac acctgataat
     5581 atgcactttt cttattttaa agattttttg cctttcttca tttcttgaat gaattggaga
     5641 gatgacttta tttaggtgtt tgacattact atagatagga tttagcagta ctaatatgaa
     5701 ctcatattat aggtgcagac ttaaattttg gaagcaagct aaaggatatc ttatctaggt
     5761 aactaagtgc tataaacaaa gtcaacgatc acttgttagg aaacgatcct aactatgctt
     5821 aataaaaaag gagaaaataa atggaactcg tattaccaaa taattatgtt gttcttgagc
     5881 aagaagagat gatgtatctt gatgggggtg gtgttggttg taactggtgg aacaaacgtg
     5941 ataatattgc tgcagctgca gtttctggag ggatgtcagt ataccagaca tatgccatta
     6001 aaaagttaat tgctaatcgt ggtatgatga gccgagtcgt tagaagtgct ataacaagat
     6061 atattggtgg agttagtatg gcaactatta ctaatgctct taatattgcg gctactgttg
     6121 ctgaagtttt ctcattagga ggagccattg catatggttt agatatcgta gacggtaaat
     6181 ttgatgg
//
LOCUS       DAVBDR010000085         5126 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.085, whole genome shotgun sequence.
ACCESSION   DAVBDR010000085 DAVBDR010000000
VERSION     DAVBDR010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5126)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5126)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5126
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.085"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            complement(56..1066)
                     /locus_tag="VQ540_001983"
     CDS             complement(56..1066)
                     /locus_tag="VQ540_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YeiH family putative sulfate export transporter"
                     /protein_id="HET2545735.1"
                     /translation="MSFLSKNGAGILACLLISIVSWYLGGFFPVIGAPVFAIFIGMLL
                     HPFLSSYKQLDAGLTFSSKKLLQYAVVLLGFGLNISQVFAVGQSSLPVILSTISIALI
                     IAYLFQRFFALDTKLATLVGVGSSICGGSAIAATAPVIDAKEKEVAQAISVIFFFNVL
                     AALIFPTLGTWLHLSNEGFALFAGTAVNDTSSVTAAASAWDSLYQSNTLESATIVKLT
                     RTLAIIPITLFLSYWQSRQQENKQSLQLKKVFPLFILYFILASLLTTLLTSLGVSSSF
                     FTPLKELSKFLIVMAMSAIGLKTNLVAMVKSSGKSILLGAICWIAIILTTLGMQTLIG
                     IF"
     gene            1215..2384
                     /locus_tag="VQ540_001984"
     CDS             1215..2384
                     /locus_tag="VQ540_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HET2545736.1"
                     /translation="MDLTKRFNKQLDKIQVSLIRQFDQVISEIPGVLRLTLGEPDFTT
                     PDHVKEAAKRAIDQNQSYYTGMSGLLTLRQAASDFVKEKYQLDYAPENEILVTIGATE
                     ALSATLTAILEEGDKVLLPAPAYPGYEPIVNLVGAEIVEIDTTENGFVLTPEMLEKAI
                     LEQGDKLKAVILNYPANPTGITYSREQLEALAAVLRKYEIFVVCDEVYSELTYTGEAH
                     VSLGTMLRDQAIIINGLSKSHAMTGWRLGLIFAPAAFTAQLIKSHQYLVTAANTMAQH
                     AAVEALTAGKNDAEPMKKEYIQRRDYIIEKMTALGFEIIKPDGAFYIFAKIPAGYNQD
                     SFAFLKDFAQKKAVAFIPGAAFGRYGEGYVRLSYAASMETIKEAMKRLEEYMREA"
     gene            2381..3151
                     /gene="recO"
                     /locus_tag="VQ540_001985"
     CDS             2381..3151
                     /gene="recO"
                     /locus_tag="VQ540_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000616164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HET2545737.1"
                     /translation="MIQSITSQGLVLYNRNFREDDKLVKIFTEQVGKRMFFVKHAGQS
                     KLAPVIQPLVLARFLLRINDDGLSYIEDYHEVMTFPKINSDLFVMAYATYVAALADAS
                     LQDNQQDAPLFAFLQKTLELMEAGLDYQVLTNIFEIQILTRFGISLNFNECVFCHRVG
                     QAFDFSFKYGACLCPEHYHEDKRRCHLNPNIPYLLNQFQAIDFETLETISLKPGIKQE
                     LRQFMDQLYEEYVGIHLKSKKFIDSLADWGQLLKEEKK"
     gene            3148..4140
                     /gene="plsX"
                     /locus_tag="VQ540_001986"
     CDS             3148..4140
                     /gene="plsX"
                     /locus_tag="VQ540_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000717456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HET2545738.1"
                     /translation="MKKIAVDAMGGDYAPQAIVEGVNQALSDFSDIEVQLYGDEAKIK
                     QYLTATERVSIIHTDEKIDSDDEPTRAIRNKKNASMVLAAKAVKDGEADAVLSAGNTG
                     ALLAAGFFIVGRIKNIDRPGLMSTLPTVDGKGFDMLDLGANAENTAQHLHQYAVLGSF
                     YAKNVRGIAQPRVGLLNNGTESSKGDPLRKETYELLAADESLNFIGNVEARDLMNGVA
                     DVVVADGFTGNAVLKSIEGTAMGIMGLLKTAITGGGLRAKLGALLLKDSLRGLKKQLN
                     YSDVGGAVLFGVKAPVVKTHGSSDAKAVYSTIRQIRTMLETDVVAQTAREFSGE"
     gene            4146..4379
                     /locus_tag="VQ540_001987"
     CDS             4146..4379
                     /locus_tag="VQ540_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HET2545739.1"
                     /translation="MTEKEIFDRIVTIIQERQGEDFVVTESLSLKDDLDADSVDLMEF
                     ILTLEDEFSIEISDEEIDQLQSVGDVVKIIQGK"
     gene            4425..4716
                     /locus_tag="VQ540_001988"
                     /pseudo
     CDS             4425..4716
                     /locus_tag="VQ540_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
     gene            4919..>5126
                     /locus_tag="VQ540_001989"
     CDS             4919..>5126
                     /locus_tag="VQ540_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin class II family protein"
                     /protein_id="HET2545740.1"
                     /translation="MNTKKMSQFEIMDTEMLACVEGGGCNWGDFAKAGVGGGAVRGLQ
                     LGIKTRTWQGAATGAAGGAILGGVA"
BASE COUNT         1543 a          944 c         1292 g         1347 t
ORIGIN      
        1 aacatatata cggcaaggcg acgttgacgt ggtttgaaga gattttcgaa gagtgttaga
       61 aaatgccgat aagggtctgc ataccaagag tggtgaggat gatggcaatc cagcagatgg
      121 ctccaagaag aatggatttt ccactggatt tgaccatagc gaccagattg gttttgagac
      181 cgatagcact catggccatg acaataagga atttagagag ttctttgaga ggggtaaaga
      241 aactactgga cacacctaga gaggtgagta gtgtagtgag gagagaggca aggataaagt
      301 aaaggataaa aagtgggaag acttttttca gttgtaggct ttgcttgttt tcttgttggc
      361 gactttgcca gtaggagaga aagagcgtga tagggataat agccaaagta cgtgtgagtt
      421 taacaatggt tgcagactcg agggtattgc tttggtaaag actgtcccaa gcgctggcgg
      481 cagccgttac agaggaagtg tcgttgaccg cagtccctgc aaagagggcg aagccttcat
      541 tggatagatg aagccaggtg ccgagggttg gaaagatgag cgcagccaag acattgaaga
      601 aaaagataac ggaaatggct tgggctactt ccttttcctt agcatcaata acgggcgctg
      661 tcgctgcaat ggcagaaccc ccacagatag aagaacctac tccaaccaag gtagccagtt
      721 ttgtatccag tgcaaagaaa cgctggaaga ggtaggcaat aatcagagct attgagatag
      781 tggacaggat gacagggagt gaagattggc caactgcgaa gacctgcgag atattgagac
      841 caaaaccaag caagacaacg gcatattgga gcaacttctt ggaactaaag gtcaaaccag
      901 catccagttg tttataggac gagagaaagg gatgtaggag catgcctatg aaaatggcaa
      961 aaacgggcgc gccaatcaca gggaagaatc ctcctaagta ccaagatacg atagaaatga
     1021 gaaggcaggc caagatacct gctccatttt ttgatagaaa tgacataaaa acctccaaat
     1081 aaaatctatt accattatag acctataaac aggaaaagta aaatagaaag tggaaagcta
     1141 ttctctaatg tatttttgcg gtcggggggc ttttgtagta taatagagat acgttttgaa
     1201 agtaggaggt atctatggac ttaactaagc gctttaataa acagttagat aaaattcaag
     1261 tttcgttgat tcgtcagttt gaccaggtta tttcggagat tcctggggtc ttgcgtttga
     1321 ccttggggga acctgatttt acaacgccag accatgtcaa ggaggcggcc aagcgagcga
     1381 ttgatcagaa ccaatcctac tatacaggga tgagtggtct gctgactcta cgtcaggcag
     1441 ccagtgactt tgttaaggaa aagtaccaac tggactatgc tcctgaaaat gaaattttgg
     1501 ttacaattgg ggcgacagag gctttatctg cgactttgac ggctattttg gaagagggag
     1561 acaaggtact tttgccagct cctgcttatc caggctatga accgattgtt aacttagttg
     1621 gggcagaaat tgttgagatt gatacgactg aaaatggttt tgtcttgact cctgagatgt
     1681 tggagaaggc cattttggag cagggtgata agctcaaggc ggttattctc aactatccag
     1741 ccaatccgac aggaattacc tacagtcgag agcagttaga ggccttggca gctgttttac
     1801 gcaagtacga aatttttgtt gtctgtgatg aggtttactc agaattgacc tacacaggcg
     1861 aagcccatgt gtctctagga acgatgttga gagaccaggc tattattatc aatggtttgt
     1921 ctaaatcgca tgccatgaca ggttggcgtt tggggctgat tttcgctcct gcggccttca
     1981 cagcccagtt aatcaagagt caccaatact tggtcactgc cgcaaatacc atggcgcaac
     2041 atgctgcggt agaagccttg acggctggta aaaatgatgc ggagcccatg aagaaggaat
     2101 atatccaacg tcgggactat atcatcgaaa aaatgactgc tcttggtttt gagattatca
     2161 aaccagacgg tgccttctat atttttgcta aaattccagc gggctacaat caagactcct
     2221 ttgcttttct gaaggatttt gctcagaaga aggccgttgc ctttatccct ggtgcagcct
     2281 ttggacgtta cggggaaggc tacgtccgcc tatcttatgc agccagcatg gagactatca
     2341 aagaagccat gaaacgactt gaggagtaca tgagagaagc atgattcagt ctatcacgag
     2401 tcaaggcttg gtgctttaca atcgcaattt tcgtgaggat gacaagctcg tcaaaatttt
     2461 tacagagcag gttggcaaac gcatgttttt tgtcaaacac gctggtcagt ctaagctggc
     2521 gcctgttatt cagcccttgg tgctggcacg atttctcttg cgaatcaatg atgacggact
     2581 cagttacatc gaagactatc atgaggtcat gacttttccc aagattaata gtgacctctt
     2641 tgtcatggcc tatgcgacct atgtggcagc tcttgcagat gctagtttgc aggacaatca
     2701 gcaggatgct cccttgtttg cttttttgca aaagactttg gagttgatgg aagcaggctt
     2761 ggattatcag gttttgacca atatttttga aattcaaatt ttgactcgat ttggaatcag
     2821 cctcaatttt aatgagtgtg tcttctgcca tcgggttggt caggcttttg acttttcttt
     2881 caaatatgga gcctgcctct gtccagagca ttatcatgag gataagagac gttgtcatct
     2941 caatcccaat atcccctatc tgctcaatca atttcaagct attgattttg agactttgga
     3001 gaccatttcg ctcaagcctg gaatcaagca agagctacgc caatttatgg atcaattata
     3061 tgaagagtac gttgggattc acctaaaatc aaagaaattt attgattccc tagcagactg
     3121 gggacaatta ctaaaagagg aaaagaaatg aaaaaaatcg cagtagatgc catggggggc
     3181 gattacgcac ctcaggccat tgttgagggt gtcaatcaag ccctatctga cttttcagat
     3241 atcgaggttc aactttacgg agatgaagct aaaatcaagc aatatctgac agcgacagag
     3301 cgcgtcagca ttatccatac ggatgagaag attgattcgg atgatgaacc tacgagagct
     3361 attaggaata agaaaaatgc cagtatggta ttggcagcca aggctgtcaa agatggtgaa
     3421 gcagacgctg tcctttcggc tgggaataca ggtgccttgt tggcagcagg attcttcatc
     3481 gtgggtcgta tcaagaatat cgaccgtcct ggactcatgt ctaccttgcc taccgttgat
     3541 ggaaaaggtt ttgacatgct agaccttggt gccaatgcag aaaatacagc ccagcacctc
     3601 catcaatatg cggttctagg ttccttctat gctaaaaatg tccgtggcat tgcgcaacca
     3661 cgcgttggtt tgctcaacaa cggaacagag agtagcaagg gcgacccgct tcgtaaggaa
     3721 acttatgaat tactggcggc tgatgaaagt ttgaacttta tcggaaacgt ggaagcgcgt
     3781 gatttgatga atggcgttgc agatgttgtt gtggcagatg gtttcacggg aaacgctgtg
     3841 ctcaaatcca tcgaagggac agctatggga atcatgggct tgctcaagac agctattaca
     3901 ggtggtggtc ttcgagcgaa actaggtgcc ctccttctca aggacagcct cagaggtttg
     3961 aaaaaacagc tcaattattc agatgttggt ggagcggtct tgtttggtgt taaggcacct
     4021 gttgtcaaga ctcatggctc aagcgatgcc aaggctgttt atagtacgat tcgtcagatc
     4081 cgtaccatgc tagaaacaga cgtggttgcc cagactgcgc gtgaattttc aggagaataa
     4141 aagagatgac agaaaaagaa atttttgacc gtattgtgac cattatccaa gagcgacagg
     4201 gagaggactt tgtcgtgaca gaatccttga gtctgaaaga cgatttggat gcggattctg
     4261 ttgacttgat ggagtttatc ttgactctgg aagatgaatt tagtatcgaa atcagcgatg
     4321 aggaaattga ccaactccaa agtgtaggag atgtggttaa aatcattcaa ggaaaatagc
     4381 aatcggagtt ccaagtcaac ggaagtagat ggtttttaga aatgagaaat atcggacaag
     4441 ctggtaaaat cttggctgac agtggttatc aagggctcat gaagatatat cctcaagcac
     4501 aaacttccac gtaaatccag caaactcaag ccgctaacag ttgaagataa agcctgtaat
     4561 catgcgctat ctaaggagag aagcaaggtt gagaatatct ttgccaaagt aaaaacgttt
     4621 aaaatgtttt caacaaccta tcgaaatcat cgtaaacgct tcggattacg aatgaatttg
     4681 attgctggta ttatcaatca tgaactagga ttctagtttt gcaggaagtc taatagtaaa
     4741 aaagtgatta gaaaacatct tttttaaaaa tagagatgat tttgaaacaa aaaagctaat
     4801 tcaagacgtt tcgatgccaa ttcaagattt ggatgaaaaa aattaataga tactgttata
     4861 ctaaacttgt caagtttgta acaagacaaa tattaaaaat aaaaaagagg tattcgttat
     4921 gaatacaaaa aagatgtcac aatttgaaat tatggatact gagatgcttg cttgcgttga
     4981 aggtggcgga tgcaattggg gagattttgc caaagcaggt gttggaggag gagcagtacg
     5041 aggtcttcag ctaggaatta aaacaagaac atggcaaggt gcagcaactg gtgctgcggg
     5101 aggagctata cttggaggtg tggcct
//
LOCUS       DAVBDR010000086         5026 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.086, whole genome shotgun sequence.
ACCESSION   DAVBDR010000086 DAVBDR010000000
VERSION     DAVBDR010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5026)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5026)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5026
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.086"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            complement(111..188)
                     /locus_tag="VQ540_001990"
                     /pseudo
     CDS             complement(111..188)
                     /locus_tag="VQ540_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            346..564
                     /locus_tag="VQ540_001991"
     CDS             346..564
                     /locus_tag="VQ540_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001859328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-export chaperone SecB"
                     /protein_id="HET2545741.1"
                     /translation="MKKISVTVIGYFEINIDENITDILYVNGTAILYHYLRSIVSIVS
                     AIDSSEAMLLPTINVLELLDKSQPFEEE"
     gene            1609..2601
                     /locus_tag="VQ540_001992"
     CDS             1609..2601
                     /locus_tag="VQ540_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET2545742.1"
                     /translation="MAMIEVEHLQKNFVKTVKEPGLKGALRSFIHPEKQTFEAVKDLT
                     FEVPKGQILGFIGANGAGKSTTIKMLTGILKPTSGFCRINGKIPQDNRQDYVKDIGVV
                     FGQRTQLWWDLALQETYTVLKEIYDVPDSLFHKRMDFLNEVLDLKDFIKDPVRTLSLG
                     QRMRADIAASLLHNPKVLFLDEPTIGLDVSVKDNIRRAITQINQEEETTILLTTHDLS
                     DIEQLCDRIFMIDKGQEIFDGTVSQLKETFGKMKTLSFELLPGQSHLVSHYDGLSDMT
                     IDRQGNSLNIEFDSSRYQSADIIKQTLSDFEIRDLKMVDTDIEDIIRRFYRKEL"
     gene            2603..3421
                     /locus_tag="VQ540_001993"
     CDS             2603..3421
                     /locus_tag="VQ540_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 family transporter protein"
                     /protein_id="HET2545743.1"
                     /translation="MIKLWRRYKPFINAGVQELITYRVNFILYRIGDVMGAFVAFYLW
                     KAVFDSSQESLIQGFSMADITLYIIMSFVTNLLTRSDSSFMIGEEVKDGSIIMRLLRP
                     VHFAASYLFTELGSKWLIFISVGLPFLSVIVLMKIISGQGIVEVLGLTVIYLFSLTLA
                     YLINFFFNICFGFSAFVFKNLWGSNLLKTSIVAFMSGSLIPLAFFPKVVSDILSFLPF
                     SSLIYTPVMIIVGKYDASQILQALLLQFFWLLVMVGLSQLIWKRVQSFITIQGG"
     gene            3423..4208
                     /locus_tag="VQ540_001994"
     CDS             3423..4208
                     /locus_tag="VQ540_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2545744.1"
                     /translation="MKKYQRMHLIFIRQYIKQIMEYKVDFVVGVLGVFLAQGLNLLFL
                     NVIFQHIPFLEGWTFQEIAFIYGFSLIPKGMDHLFFDNLWALGQRLVRKGEFDKYLTR
                     PINPLFHILVETFQIDALGELLVGGILLGTTVTSIVWTLPKFLLFLVCIPFATLIYTS
                     LKIATASIAFWTKQSGAMIYIFYMFNDFAKYPISIYNSLLRWLISFIVPFAFTAYYPA
                     SYFLQEKDVFFNVGGLMLISLVFFVISLKLWDKGLDSYESAGS"
     gene            4247..4525
                     /locus_tag="VQ540_001995"
     CDS             4247..4525
                     /locus_tag="VQ540_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family acetyltransferase"
                     /protein_id="HET2545745.1"
                     /translation="MFVIEEVKDENQKKAVVAEVLKDLPEWFGIPESTQAYIEGTTTL
                     QVWTAYQESDLTRFVSLSYSSEDCAEIDCLGVKKLIKVEKLGANCLLL"
     gene            4510..4707
                     /locus_tag="VQ540_001996"
     CDS             4510..4707
                     /locus_tag="VQ540_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2545746.1"
                     /translation="MLATLESEARKKVGYLQVKTVAEGSNKDYDRTNDFYRGLGFKKL
                     EIFPQLWNPQNPCQILIKKLE"
BASE COUNT         1442 a          835 c         1050 g         1699 t
ORIGIN      
        1 gaaatctagt ggaatgaatc tggaatagtc catcgagctt tctaatactc ttcgaaaatc
       61 tcttcaaacc acgtcaacgt cgccttgccg tgcgtatggt tactgacttc gtcagttcta
      121 tccacaacct caaaacagtg ttttgagcaa cctgaggcta gtttcctagt ttgctctttg
      181 gttttcattt agtataacag attgttagaa gttggtttaa atttcctaat cagtttgttc
      241 acatttacct tcgatatatt atatcccata gttaaggttg gtcatacaga tgattatagt
      301 catggagccg taaaacttag tgtttcttta gttgacaaag atgccatgaa aaaaatatct
      361 gtaactgtaa taggatattt tgaaataaat atagatgaaa atatcaccga tattctatac
      421 gtaaatggta ctgctattct ttatcattat ttacgttcta ttgtttcaat agtttcggca
      481 attgatagca gtgaagcaat gttgctacct accattaatg ttttagagtt actagataaa
      541 tctcaacctt ttgaagaaga ataatttatt agctcactaa attgagggta aggaaaagta
      601 aaatcagtaa gaaaaatgtc ttgcattata cagcaacctt ttgggaatga gtagatggat
      661 tgaataaaat tttattaaga gtggatgatt tatctgtaga ttattattgg acagttagtc
      721 ttgaagtagt ctaagaatta ggttataatc agtagaatcc ttgctaataa tgaggaggtt
      781 agtttatgta tagtagactg aatctaaaat agtacgaaac aattgctaaa acatttatag
      841 aaattaattt tactttccca atcgatttgt tctcatctta tttcaatccg ctatatatta
      901 tggtatcgaa tcttcatcag aatgataaaa ttaatcaatt gatatctgat tacaaacaga
      961 atatgaaagc tttttatatc actattgaaa aatttatacg agatgatgaa agccttaagt
     1021 gttattttat aaaggttatt tcaagtcgtt ccaaggtaac aagtctagat cagattgaag
     1081 ctgataaaac gatacaaaga aaatattcaa gtgagctaaa aaaatttatt ggattttata
     1141 atgagattat ttgtgaggaa aatagtttcc tacatgtacg aaagaggtgg tcgagttggt
     1201 ttaggtagtc gatgcgtgag ttgataattc tcagggtatg gacttctttt tcatgaatga
     1261 ggtaaaagag caggtattgt ttagagacaa tcattctgag catattttct ggatagaggg
     1321 agtatccgat tttatgatca aagttaatac cgccctctgg tgagaagatg agtaggttgg
     1381 taatttaaac tattaaacag aatttttgat taaaagtatt attttatgag agaaatccta
     1441 atttcacaat ccataggcaa actcttgcat ttcgtttttt attggactat aataggttgg
     1501 tataaagcct tttgtagtaa taaaatgtag aaggtgtaga aagcaaggat ttagaatatt
     1561 tgtagttaaa aacacaatgt tgctattcct tacgataggg agatagatat ggcaatgata
     1621 gaagtggaac atcttcagaa aaattttgtg aagactgtta aggaaccggg cttgaagggg
     1681 gctttgcgct cctttattca tcctgaaaag cagacctttg aagcggtcaa ggatttgacc
     1741 tttgaggttc caaaagggca gattttagga tttatcgggg caaatggtgc tgggaagtcg
     1801 acaaccatta aaatgctgac aggaattttg aaaccaacat ctggtttttg tcggattaac
     1861 ggcaagattc cccaggacaa tcggcaagat tatgtcaaag atattggcgt agtctttgga
     1921 caacgcaccc agctatggtg ggatttggct ctgcaagaga cctacactgt cttaaaagag
     1981 atttatgatg tgccagactc gctctttcat aagcgtatgg actttttgaa tgaagtcttg
     2041 gatttgaagg actttatcaa ggatcccgtg cggactcttt cactgggaca acggatgcgg
     2101 gcggatattg cggcctcctt gctccacaat cccaaggttc tttttttaga tgagccgacc
     2161 attggtttgg acgtttcggt taaggataat attcgtcggg caattactca gatcaatcaa
     2221 gaggaagaaa ctaccattct tttgaccact cacgatttga gtgatattga gcaactttgt
     2281 gatcggattt tcatgattga caaggggcaa gagatttttg atggaacggt gagccaactc
     2341 aaggagacct ttggtaagat gaagactctc tcttttgaac tgctaccagg tcaaagtcat
     2401 ctcgtctctc actatgacgg tctgtctgat atgaccattg atagacaagg aaacagcctc
     2461 aacattgaat ttgatagttc tcgctaccag tcagctgaca ttatcaagca aaccctgtct
     2521 gattttgaaa tccgcgattt gaagatggtg gatacggata ttgaggatat tatccgtcgc
     2581 ttctaccgaa aggagctcta ggatgatcaa attgtggaga cgttataaac cctttatcaa
     2641 tgcaggggtt caggagttga ttacttaccg agtcaacttt attctctatc ggattggcga
     2701 tgtcatgggg gcttttgtgg ccttttatct ctggaaggct gtctttgatt cttcgcaaga
     2761 gtctttgatt cagggcttca gtatggcgga tatcaccctc tacatcatca tgagttttgt
     2821 gaccaatctt ctgactagat ccgattcgtc ctttatgatt ggggaggagg tcaaggatgg
     2881 ctccattatc atgcgtttgt tgcgaccagt gcattttgcg gcctcctatc ttttcaccga
     2941 gcttggttcc aagtggttga tttttatcag cgttggcctt ccatttttaa gtgtcattgt
     3001 cttgatgaaa atcatatcgg gtcaaggtat tgtagaggtg ctaggattaa ctgtcattta
     3061 tctttttagc ttaacgctcg cctatctgat taactttttc tttaatattt gctttggatt
     3121 ttcagccttt gtgtttaaaa atctttgggg ttccaaccta cttaagactt ccatagtggc
     3181 ttttatgtcg gggagtttga ttcccttggc attctttcca aaggttgttt cagatattct
     3241 ctcctttttg cctttttcat ccttgattta tactccagtt atgatcattg ttggaaaata
     3301 cgatgccagt cagattcttc aggcactcct tttgcagttc ttctggctct tagtgatggt
     3361 gggattgtct cagttgattt ggaaacgggt ccagtccttt atcaccattc aaggaggtta
     3421 gtatgaaaaa atatcaacga atgcatctga tttttatcag acaatacatc aaacaaatca
     3481 tggaatataa ggtggatttt gtggttggtg tcttgggagt ctttctggct caaggcttga
     3541 atctcttgtt tctcaatgtc atctttcaac atattccatt cctagaaggc tggacctttc
     3601 aagagatagc tttcatttat ggattttcct tgattcccaa gggaatggac catctctttt
     3661 ttgacaatct ctgggcacta gggcaacgcc tagtccgaaa aggggagttt gacaagtatc
     3721 tgactcgtcc catcaatcct ctctttcaca tcctagttga aacctttcag attgatgcct
     3781 tgggtgaact cttagtcggt ggtattttat tgggaacaac agtgaccagc attgtttgga
     3841 ctcttccgaa attcctgctt ttcctagttt gtattccttt tgcgaccttg atttatactt
     3901 ctcttaaaat cgcaacagcc agtatcgcct tttggactaa gcagtcaggc gccatgattt
     3961 acatcttcta tatgttcaat gactttgcta agtatccgat ttctatttac aattctcttc
     4021 ttcgttggtt gattagcttt atcgtgcctt tcgcctttac agcctactat ccagctagct
     4081 atttcttaca ggaaaaggat gtgttcttta acgtaggagg tttgatgttg atttctctgg
     4141 ttttctttgt tatttccctt aaactttggg ataagggctt agattcctac gaaagtgcgg
     4201 gttcgtaaaa gctaaagtaa gactaaaatc aagaaagaaa cttatgatgt ttgtaattga
     4261 agaagtcaag gatgaaaatc aaaaaaaggc agttgtagct gaggttttga aggatttgcc
     4321 agaatggttt ggaatcccag aaagcacaca agcctatata gaaggaacca cgacactgca
     4381 agtttggacc gcctatcagg agagtgattt gactagattt gtaagcttat cctattcgag
     4441 tgaagattgt gcagagattg attgtctcgg cgtaaaaaag cttatcaagg tagaaaaatt
     4501 gggagccaat tgcttgctac tttagagagt gaagctcgta aaaaagttgg ttatctgcag
     4561 gtcaaaacag tggcagaagg ttctaataaa gattatgatc gaacaaatga cttttatcga
     4621 ggtcttggct ttaaaaagtt agagattttt cctcaactat ggaatccgca aaatccttgt
     4681 cagattttga ttaaaaagct tgaataatat tacttgacat ctattctcag agtgccatac
     4741 tgtaagtgta atcgccgatt tagctcagtt ggtagagcaa ggcactcgta aagcctaggt
     4801 tataggtaga taaacgactg aggagttgaa aaaatagata ggtagaagat aaccgttaag
     4861 ccttattctt agcggttatt tatattgttt aatagcgctg atatttcatc aattatgcct
     4921 gttttcgtgt ttctggtagt tgttcaagtt tattgctact atttttgatg gtatgaatgt
     4981 gcttataatg tatcccggtt aacgaaagtt ttggacttat actctt
//
LOCUS       DAVBDR010000087         4574 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.087, whole genome shotgun sequence.
ACCESSION   DAVBDR010000087 DAVBDR010000000
VERSION     DAVBDR010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4574)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4574)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4574
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.087"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            51..1596
                     /locus_tag="VQ540_001997"
     rRNA            51..1596
                     /locus_tag="VQ540_001997"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
     gene            1648..1720
                     /locus_tag="VQ540_001998"
     tRNA            1648..1720
                     /locus_tag="VQ540_001998"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1681..1683,aa:Ala,seq:tgc)
     gene            1845..>4574
                     /locus_tag="VQ540_001999"
     rRNA            1845..>4574
                     /locus_tag="VQ540_001999"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT         1256 a          946 c         1367 g         1005 t
ORIGIN      
        1 gaaaaaaaca ataaatctgt cagtgacaga aatgagtgag aactcaaact tttaatgaga
       61 gtttgatcct ggctcaggac gaacgctggc ggcgtgccta atacatgcaa gtagaacgct
      121 gaaggaggag cttgcttctc tggatgagtt gcgaacgggt gagtaacgcg taggtaacct
      181 gcctggtagc gggggataac tattggaaac gatagctaat accgcataag agtagatgtt
      241 gcatgacatt tgcttaaaag gtgcacttgc atcactacca gatggacctg cgttgtatta
      301 gctagttggt ggggtaacgg ctcaccaagg cgacgataca tagccgacct gagagggtga
      361 tcggccacac tgggactgag acacggccca gactcctacg ggaggcagca gtagggaatc
      421 ttcggcaatg gacggaagtc tgaccgagca acgccgcgtg agtgaagaag gttttcggat
      481 cgtaaagctc tgttgtaaga gaagaacgag tgtgagagtg gaaagttcac actgtgacgg
      541 tatcttacca gaaagggacg gctaactacg tgccagcagc cgcggtaata cgtaggtccc
      601 gagcgttgtc cggatttatt gggcgtaaag cgagcgcagg cggttagata agtctgaagt
      661 taaaggctgt ggcttaacca tagtaggctt tggaaactgt ttaacttgag tgcaagaggg
      721 gagagtggaa ttccatgtgt agcggtgaaa tgcgtagata tatggaggaa caccggtggc
      781 gaaagcggct ctctggcttg taactgacgc tgaggctcga aagcgtgggg agcaaacagg
      841 attagatacc ctggtagtcc acgctgtaaa cgatgagtgc taggtgttag accctttccg
      901 gggtttagtg ccgtagctaa cgcattaagc actccgcctg gggagtacga ccgcaaggtt
      961 gaaactcaaa ggaattgacg ggggcccgca caagcggtgg agcatgtggt ttaattcgaa
     1021 gcaacgcgaa gaaccttacc aggtcttgac atccctctga ccgctctaga gatagagttt
     1081 tccttcggga cagaggtgac aggtggtgca tggttgtcgt cagctcgtgt cgtgagatgt
     1141 tgggttaagt cccgcaacga gcgcaacccc tattgttagt tgccatcatt tagttgggca
     1201 ctctagcgag actgccggta ataaaccgga ggaaggtggg gatgacgtca aatcatcatg
     1261 ccccttatga cctgggctac acacgtgcta caatggctgg tacaacgagt cgcaagccgg
     1321 tgacggcaag ctaatctctt aaagccagtc tcagttcgga ttgtaggctg caactcgcct
     1381 acatgaagtc ggaatcgcta gtaatcgcgg atcagcacgc cgcggtgaat acgttcccgg
     1441 gccttgtaca caccgcccgt cacaccacga gagtttgtaa cacccgaagt cggtgaggta
     1501 accgtaagga gccagccgcc taaggtggga tagatgattg gggtgaagtc gtaacaaggt
     1561 agccgtatcg gaaggtgcgg ctggatcacc tcctttctaa ggataaggaa ctgcgcattg
     1621 gtcttgttta gtcttgagag gtcttgtggg gccttagctc agctgggaga gcgcctgctt
     1681 tgcacgcagg aggtcagcgg ttcgatcccg ctaggctcca ttggtgagag atcaccaagt
     1741 aatgcacatt gaaaattgaa tatctatatc aaatagtaac aagaaaataa accgaaaacg
     1801 ctgtagtatt aataagagtt tatgactgaa aggtcagaaa ataaggttaa gttaataagg
     1861 gcgcacggtg gatgccttgg cactaggagc cgacgaagga cgtgacaaac gacgatatgc
     1921 cttgggtagc tgtaagtaag cgatgatcca gggatttccg aatgggggaa cccaacaggt
     1981 agtacctgtt acccacatct gttaaggatg tgaggaggaa gacgcagtga actgaaacat
     2041 ctaagtagct gcaggaagag aaagcaaaag cgattgcctt agtagcggcg agcgaaacgg
     2101 caggagggca aaccgaagag tttactcttc ggggttgtag gactgcaatg tggactcaaa
     2161 gattatagaa gaatgatttg ggaagatcag ccaaagagag taatagcctc gtatttaaaa
     2221 tagtctttgt acctagcagt atcctgagta cggcgggaca cgtgaaatcc cgtcggaatc
     2281 tgggaggacc atctcccaac cctaaatact ccctagtgac cgatagtgaa ccagtaccgt
     2341 gagggaaagg tgaaaagcac cccgggaggg gagtgaaata gaacctgaaa ccgtgtgcct
     2401 acaacaagtt cgagcccgtt aatgggtgag agcgtgcctt ttgtagaatg aaccggcgag
     2461 ttacgttatg atgcgaggtt aagttgaaga gacggagccg tagggaaacc gagtctgaat
     2521 agggcgcctt agtatcatga cgtagacccg aaaccatgtg acctacccat gagcaggttg
     2581 aaggtgcggt aagacgcact ggaggaccga accagggcac gttgaaaagt gcttggatga
     2641 cttgtgggta gcggagaaat tccaaacgaa cttggagata gctggttctc tccgaaatag
     2701 ctttagggct agcgtcgaca ttagagattc ttggaggtag agcactgttt gggtgagggg
     2761 tccatcccgg attaccaatc tcagataaac tccgaatgcc aatgaattat ggtcggcagt
     2821 cagactgcga gtgctaagat ccgtagtcga aagggaaaca gcccagacca ccagctaagg
     2881 tcccaaaata attgttaagt ggaaaaggat gtggggttgc acagacaact aggatgttag
     2941 cttagaagca gctattcatt caaagagtgc gtaatagctc actagtcgag tgaccctgcg
     3001 ccgaaaatgt accggggcta aaacaattta ccgaagctgt ggataccttt ataggtatgg
     3061 taggagagcg ttctatgtgt gatgaaggta taccgtgagg agtgctggaa cgcatagaag
     3121 tgagaatgcc ggtatgagta gcgaaagaca ggtgagaatc ctgtccaccg taagactaag
     3181 gtttccaggg gaaggctcgt ccgccctggg ttagtcggga cctaaggaga gaccgaaagg
     3241 tgtatccgat ggacaacagg ttgatattcc tgtactagag tatgtagtga tggagggacg
     3301 cagtaggcta actaaagcag acgattggaa gagtctgtct aagcagtgag gtgtgatatg
     3361 agtcaaatgc ttatatctgt aacattgagc tgtgatgggg agcgaagttt agtagcgaag
     3421 ttagtgacgt cacactgcca agaaaagctt ctagcgttta aacatactct acccgtaccg
     3481 caaaccgaca caggtagtcg aggcgagtag cctcaggtga gcgagagaac tctcgttaag
     3541 gaactcggca aaatgacccc gtaacttcgg gagaaggggt gctgacttta agtcagccgc
     3601 agtgaatagg cccaagcaac tgtttatcaa aaacacagct ctctgctaaa tcgtaagatg
     3661 atgtataggg ggtgacgcct gcccggtgct ggaaggttaa gaggagtgct tagcgtaagc
     3721 gaaggtatga attgaagccc cagtaaacgg cggccgtaac tataacggtc ctaaggtagc
     3781 gaaattcctt gtcgggtaag ttccgacccg cacgaaaggc gtaatgattt gggcactgtc
     3841 tcaacgagag actcggtgaa attttagtac ctgtgaagat gcaggttacc cgcgacagga
     3901 cggaaagacc ccatggagct ttactgcagt ttgatattga gtgtctgtac cacatgtaca
     3961 ggataggtag gagtctaaga gatcgggacg ccagtttcga aggagacgct gttgggatac
     4021 tacccttgtg ttatggccac tctaacccag ataggtgatc cctatcggag acagtgtctg
     4081 acgggcagtt tgactggggc ggtcgcctcc taaaaggtaa cggaggcgcc caaaggttcc
     4141 ctcagaatgg ttggaaatca ttcgcagagt gtaaaggtat aagggagctt gactgcgaga
     4201 gctacaactc gagcagggac gaaagtcggg cttagtgatc cggtggttcc gtatggaagg
     4261 gccatcgctc aacggataaa agctaccctg gggataacag gcttatctcc cccaagagtt
     4321 cacatcgacg gggaggtttg gcacctcgat gtcggctcgt cgcatcctgg ggctgtagtc
     4381 ggtcccaagg gttgggctgt tcgcccatta aagcggcacg cgagctgggt tcagaacgtc
     4441 gtgagacagt tcggtcccta tccgtcgcgg gcgtaggaaa tttgagagga tctgctccta
     4501 gtacgagagg accagagtgg acttaccgct ggtgtaccag ttgtcttgcc aaaggcatcg
     4561 ctgggtagct atgt
//
LOCUS       DAVBDR010000088         4552 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.088, whole genome shotgun sequence.
ACCESSION   DAVBDR010000088 DAVBDR010000000
VERSION     DAVBDR010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4552)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4552)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4552
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.088"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            complement(112..549)
                     /locus_tag="VQ540_002000"
     CDS             complement(112..549)
                     /locus_tag="VQ540_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HET2545747.1"
                     /translation="MSQEFINPSDGVIRQYLATSKTLAVVGLSDREETTSNRVTKEMQ
                     ARGYKIIPVNPKAAGGEILGEKAYASLAEIPFPVDIVNVYRRSEFLPDVARDFLKADA
                     KIFWAQLGLESLEAKEILRDGGCDDIVMNRCIKREHTRLIEEA"
     gene            complement(634..3267)
                     /gene="polA"
                     /locus_tag="VQ540_002001"
     CDS             complement(634..3267)
                     /gene="polA"
                     /locus_tag="VQ540_002001"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014932012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HET2545748.1"
                     /translation="MDKKKLLLIDGSSVAFRAFFALYQQLDRFKNAAGLHTNAIYGFQ
                     LMLSHLLERVEPSHILVAFDAGKTTFRTEMYADYKGGRAKTPDEFREQFPFIRELLDH
                     MGIRHYELAQYEADDIIGTLDKLAEQDGFDITIVSGDKDLIQLTDEHTVVEISKKGVA
                     EFEAFTPDYLMEEMGLTPAQFIDLKALMGDKSDNIPGVTKVGEKTGIKLLLEHGSLEG
                     IYENIDGMKTSKMKENLINDKEQAFLSKTLATIDTKAPIAIGLEDLVYSGPDVENLGK
                     FYDEMGFKQLKQALNVSSADVAEGLDFTIVDQISQDMLSEESIFHFELFGENYHTDNL
                     VGFAWSCGDKLYATDKLELLQDPIFKDFLEKTSLRVYDFKKVKVLLQRFGVDLQAPAF
                     DIRLAKYLLSTVEDNEIATIASLYGQTYLVDDETFYGKGVKKAIPEREKFLEHLACKL
                     AVLVETEPILLEKLSENGQLELLYDMEQPLAFVLAKMEIAGIVVKKETLLEMQAENEL
                     VIEKLTQEIYELAGEEFNVNSPKQLGVLLFEKLGLPLEYTKKTKTGYSTAVDVLERLA
                     PIAPIVKKILDYRQIAKIQSTYVIGLQDWILADGKIHTRYMQDLTQTGRLSSVDPNLQ
                     NIPARLEQGRLIRKAFVPEWEDSVLLSSDYSQIELRVLAHISKDEHLIKAFQEGADIH
                     TSTAMRVFGIERPDNVTANDRRNAKAVNFGVVYGISDFGLSNNLGISRKEAKAYIDTY
                     FERFPGIKNYMDEVVREARDKGYVETLFKRRRELPDINSRNFNIRGFAERTAINSPIQ
                     GSAADILKIAMIQLDKALVAGGYQTKMLLQVHDEIVLEVPKSELVEMKKLVKQTMEEA
                     IQLSVPLIADENEGATWYEAK"
     gene            3520..3873
                     /locus_tag="VQ540_002002"
     CDS             3520..3873
                     /locus_tag="VQ540_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
                     /protein_id="HET2545749.1"
                     /translation="MILRHLGISPTNDLVAKKIFSNPEITCQFIRDMLDLPAKNVTIL
                     EGSNIHVLPSMPYSAQDFYTSIDVLAELDNGTQVIIEIQVHHQNFFINHLWAYLCSQV
                     NQNLEKIRQREGDTH"
     gene            4088..4204
                     /locus_tag="VQ540_002003"
     CDS             4088..4204
                     /locus_tag="VQ540_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000233180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
                     /protein_id="HET2545750.1"
                     /translation="MVGVFRQQALYPATATSHYPSKSTAGLQELVRGGQENV"
     gene            4197..4430
                     /locus_tag="VQ540_002004"
     CDS             4197..4430
                     /locus_tag="VQ540_002004"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2545751.1"
                     /translation="MFSQLHMREEQVLLAQDYALETARAEGLEQGLERGKVEGRAERK
                     LFAFLDIVRQGLLTSEVASQQLGMSVSEFEALL"
BASE COUNT         1385 a         1096 c          837 g         1234 t
ORIGIN      
        1 gtatctacaa cctcaaaaca gtgttttgag cagcccgcga ctagtttcct agtttgctct
       61 ttgattttca ttgagtataa cacaaaaggt agcccatcag ctaccttttt cttatgcttc
      121 ctcaatcaag cgagtatgtt ctctcttgat acagcgattc atcacgatat catcacatcc
      181 accatcacgc aaaatctctt tcgcttctaa actttcaagt cctagctgtg cccaaaaaat
      241 cttggcatca gctttgagaa aatcacgcgc cacatcgggc agaaattcac tgcgacgata
      301 aacattgaca atatctacag gaaaaggaat ttcagcgagg ctagcataag ccttttcacc
      361 caagatttcg ccacctgccg ccttgggatt gactgggatg attttatagc cccgagcctg
      421 catttccttt gtcactcgat tgctggttgt ttcttcacgg tcagacaaac ccaccacagc
      481 aagggtttta ctcgttgcga gatactgacg aatcacgcca tcacttggat tgataaattc
      541 ttgactcata gaaaacctcc tttttcatca gtatagcaca ttttgaaaag gtttgcagaa
      601 ttctactaca aaaaaggagg actagccccc tttttattta gcctcgtacc aggttgcccc
      661 ttcattctca tctgcgataa gaggaacact gagttgaatg gcttcttcca tggtttgttt
      721 caccaatttt ttcatctcta ccaattcaga tttaggcact tcaaggacga tttcatcgtg
      781 cacttgtaac agcatcttag tctgataacc acctgcaacc aaggctttat ccagctgaat
      841 catggcaatc ttgagaatat ctgctgccga accctggata ggtgagttga tagcagttcg
      901 ctccgcaaaa ccacgaatat tgaagttgcg cgaattgata tctggcaact cacggcgacg
      961 cttaaagagg gtctctacat agcccttatc acgcgcctcc cgcaccactt catccatgta
     1021 gtttttaata cctggaaaac gttcaaagta ggtatcaatg taggctttgg cttccttacg
     1081 actaattccc aaattattag acaagccaaa gtctgaaatc ccataaacca ctccaaagtt
     1141 aactgccttg gcattgcgac gatcatttgc agtcacatta tcaggacgct caatgccaaa
     1201 gacccgcatg gctgtcgaag tatggatatc tgccccctct tggaaggcct taatcaagtg
     1261 ctcatcctta gaaatatgcg ccaaaacgcg caattcaatc tgtgaatagt cagagctgag
     1321 tagcacacta tcctcccact ctggcacaaa agccttccga atcaagcgcc cttgttccaa
     1381 tcgggcagga atattttgca agtttggatc cacactagac aaacgcccgg tctgggtcaa
     1441 atcctgcata tagcgagtat gaatctttcc atcagccaaa atccagtcct gcaagccaat
     1501 tacataagta gattgaatct tagcaatttg acggtaatcc aggattttct taacaatcgg
     1561 agcaatagga gcgagacgct ccaacacatc cactgctgtc gaataacctg tcttggtttt
     1621 cttagtgtat tctagaggaa gtcccaattt ctcaaagaga agcacgccca actgcttagg
     1681 cgagttgaca ttaaactcct caccagccag ctcgtaaatc tcttgagtca gtttttcaat
     1741 gacaagctca ttttcagcct gcatctcaag caaggtctct ttcttgacca caatcccagc
     1801 aatttccatc ttggcaagaa caaaagccag aggttgctcc atatcataaa gaagctctaa
     1861 ttgcccattt tcgctgagtt tttcaagtaa aataggctct gtttctacca aaacagcaag
     1921 tttacaagct aagtgttcca agaatttctc acgttcagga atggcctttt taacaccctt
     1981 accgtagaaa gtttcatcat caaccaagta agtctgacca taaagactag cgatggtcgc
     2041 aatttcattg tcctccacag tcgaaaggag gtatttagcc aaacggatgt caaaagcagg
     2101 cgcctgcaaa tccacaccaa aacgttgcaa aagaacttta accttcttaa agtcataaac
     2161 tctcagagat gttttttcta agaaatcctt gaaaatcggg tcttgcaaca gctcaagctt
     2221 gtctgtggca tagagcttat ccccacaaga ccaggcaaat ccaaccaaat tatccgtatg
     2281 ataattctca ccaaaaagct caaagtggaa gatagactct tcactcagca tatcttgact
     2341 gatttggtca acaatagtaa aatccaaacc ctcagccaca tcagctgacg acacatttaa
     2401 agcctgcttg agctgtttga atcccatctc atcgtaaaat ttcccaagat tttcaacatc
     2461 tggaccacta tagaccaagt cctctaaacc aatcgcaatc ggtgccttgg tatcaatggt
     2521 cgctagtgtt ttagacaaaa aggcctgttc cttgtcattg atgagatttt ccttcatctt
     2581 agaagtcttc attccatcaa tattttcata aatcccctca agcgaaccat gctccagcaa
     2641 gagcttaata cccgtctttt caccgacttt ggtcacccca gggatattat ccgacttatc
     2701 acccatgagc gccttgagat cgataaactg agctggtgtg aggcccattt cttccatgag
     2761 gtaatctggc gtaaaggcct caaactcagc cacacctttc ttggaaattt caaccaccgt
     2821 atgctcatcc gtcagctgaa tcaaatcctt gtccccactg acaatggtaa tatcaaaacc
     2881 atcctgctct gctagcttat ccaacgtccc aatgatgtca tccgcctcat actgagccag
     2941 ctcatagtga cgaatcccca tatgatccag caactcacga atgaaaggaa attgctcacg
     3001 aaactcatca ggagtcttgg cccgaccacc cttatagtcc gcatacatct ctgtccggaa
     3061 ggtcgtcttt cccgcatcaa aagccaccaa aatatgactc ggctcaaccc gctccaacaa
     3121 atgactcaac atcaactgaa aaccataaat cgcattggta tgcaaaccag ccgcattctt
     3181 aaaacggtcc aactgctgat acagcgcaaa aaacgcccga aaagctacag aagacccatc
     3241 aatcaataat aattttttct tatccataca cccattataa aggaaagaat caaaaaatac
     3301 cattgggaag agctagagca agtatttttc aaactttttc cgaataaata gatagagcca
     3361 gagaatttag taaacctaga tttaaaaatg tgctataata tagtatattg aatctataat
     3421 agtacacctt gactgctaaa atatttctat aaattaattt gactttcctg atagagttgt
     3481 tcacatctta tttcaattca ctatagaagg aggaaaagga tgattctcag acatctggga
     3541 attagcccga ccaatgactt ggttgctaag aaaattttca gcaacccaga aatcacttgt
     3601 caatttatcc gcgatatgct ggacttgcca gccaaaaatg tgactatttt ggagggaagt
     3661 aacattcatg tcttgccttc catgccctac tcagcgcagg atttttatac cagtatagac
     3721 gtcttggcgg agttggataa cggtactcaa gtaattattg agattcaagt ccatcatcag
     3781 aattttttca tcaatcactt gtgggcttac ctgtgcagtc aggttaatca aaatcttgaa
     3841 aaaattcgtc agcgagaagg tgatactcac tagatctaca aacacatcgc tcctgtttac
     3901 gtcattgcta tcgtggatag taattatttc tcagatgacc tggcttttca tagctttagt
     3961 atgcgcgaag acacaacagg tgaggtattg gcgattacca acaatggaca ggaaaaccat
     4021 ctggttaaga tggcattctt ggaattaaaa aatacagaga aaccagcaaa gacaaggttc
     4081 gcaagccatg gttggagttt ttcggcaaca agccctttac ccagcaaccg caacgagcca
     4141 ttacccaagc aaatcaactg ctggactaca agagctggtc cgaggaggac aggaaaatgt
     4201 ttagtcaact acatatgcga gaagaacaag tcttgttagc acaggactat gccttggaaa
     4261 ctgctagggc tgaaggcctt gaacaaggac tagagcgtgg gaaagttgaa ggaagggcag
     4321 aaaggaaact ttttgccttc ctagacatag tacgccaagg tcttctgact tctgaggttg
     4381 ccagccagca attaggtatg tcagtatctg aatttgaggc actgttgtaa aatggctcca
     4441 taatatccat agtgggtaaa tcccctatgg atattatgga gcctattttt gtgtagaaaa
     4501 aaagtcccat atgacctata atgaaaagcg acaaaacaac tcattaaaaa ga
//
LOCUS       DAVBDR010000089         4528 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.089, whole genome shotgun sequence.
ACCESSION   DAVBDR010000089 DAVBDR010000000
VERSION     DAVBDR010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4528)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4528)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4528
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.089"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            <1..141
                     /locus_tag="VQ540_002005"
     CDS             <1..141
                     /locus_tag="VQ540_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2545752.1"
                     /translation="LLPLPPYSPEYNPIEKTWAHIKKHLKKVLPSCNTFYEALLSCSC
                     FN"
     gene            complement(134..307)
                     /locus_tag="VQ540_002006"
     CDS             complement(134..307)
                     /locus_tag="VQ540_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001022221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteinase"
                     /protein_id="HET2545753.1"
                     /translation="MNIKKRVLSAGLTFASVLLLAACGQSGSDTKTYSSTFSGNPTTF
                     NYLLDYYTDNIVN"
     gene            complement(465..2072)
                     /locus_tag="VQ540_002007"
     CDS             complement(465..2072)
                     /locus_tag="VQ540_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HET2545754.1"
                     /translation="MQEKWWHNAVVYQVYPKSFMDSNGDGIGDLPGITSKLDYLAKLG
                     ITAIWLSPVYDSPMDDNGYDIADYQAIAAIFGTMEDMDQLIAEAKKRDIRIIMDLVVN
                     HTSDEHAWFVEACENPNSPERDYYIWRDEPNDLDSIFSGSAWEYDEKSGQYYLHFFSK
                     KQPDLNWENEKLRQKIYEMMNFWIDKGIGGFRMDVIDMIGKIPDEKVVNNGPMLHPYL
                     KEMNQATFGDKDLLTVGETWGATPEIAKLYSDPKGQELSMVFQFEHIGLQYQEGQPKW
                     HYQKELNIAKLKEIFNKWQTELGVEDGWNSLFWNNHDLPRIVSIWGNDQEYREKSAKA
                     FAILLHLMRGTPYIYQGEEIGMTNYPFETLDQVEDIESLNYAREALEKGVPIEEIMDS
                     IRVIGRDNARTPMQWDESKNAGFSTGQPWLAVNPNYEMINVQEALANPDSIFYTYQKL
                     VQIRKENSWLVRADFELLDTADKVFAYIRKDGDRRFLVVANLSNEEQDLTVEGKVKSV
                     LIENTLAQEVFEKQILVPWDAFCVELL"
     gene            2225..3709
                     /locus_tag="VQ540_002008"
     CDS             2225..3709
                     /locus_tag="VQ540_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008535024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HET2545755.1"
                     /translation="MKKQAFSSEQYLNLQRDHILERINQFDGKLYLEFGGKMLEDFHA
                     ARVLPGYEPDNKIKLLQELKEQVEVVIAINASNIEHSKARGDLGISYDQEVLRLIDKF
                     NELGIFVGSVVITQYAGQPAADAFLNQLEKNGIDSYLHYPIKGYPTDMDHIISPEGMG
                     KNDYIKTSRNLIVVTAPGPGSGKLATCMSNMYHDQINGIKSGYAKFETFPVWNLPLHH
                     PVNLAYEAATADLDDVNMIDPFHLQTYGETTVNYNRDIEIFPVLKRMLERILGKSPYA
                     SPTDMGVNMVGFAITDDEAAVEASKQEIIRRYYQTVLDFKAEKVGEAAVKKIELLMND
                     LGISPADRKVAVVARQKAEETGGPALALELPNGDIVTGKNSELFGPTAAALINAIKKS
                     ADIAKEVKLIEPEVVKPIQGLKIDHLGSRNPRLHSNEILIALAITATENPDAARAMEE
                     LGNLKGSEAHSTIILTDEDKNVLRKLGINVTFDPYYQYDRLYRK"
     gene            3804..4286
                     /locus_tag="VQ540_002009"
     CDS             3804..4286
                     /locus_tag="VQ540_002009"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HET2545756.1"
                     /translation="MSKEVIVESFELDHTIVKAPYVRLIGEETGPKGDIISNYDIRLV
                     QPNEDSIPTAGLHTIEHLLAKLIRTRIDGMIDCSPFGCRTGFHMIMWGRHTSAKIAAV
                     IKDSLKEIAETTTWEDVPGTTIESCGNYKDHSLFSAKEWAKLILEQGISDDAFERHVI
                     "
BASE COUNT         1313 a         1042 c          856 g         1317 t
ORIGIN      
        1 cttttacctc ttcctcccta ctcacctgag tacaatccta ttgagaaaac atgggctcat
       61 atcaaaaagc acctcaaaaa ggtattacca agttgcaata ccttttatga ggctcttttg
      121 tcttgttctt gtttcaattg actatattat cagtgtaata gtctaataga tagttaaatg
      181 tagttggatt tccactaaag gttgatgagt aagtttttgt atctgaacct gattggccgc
      241 aagcagctaa aagcaaaaca gatgcaaaag tcaggcctgc actaaggaca cgcttcttta
      301 tgttcatctt ctttctcctt aatagtggga atttgtaaag ttaattgaat ttcgagaatg
      361 aaagtttata aaccttggtt ataaaaaaca aaggatttct gcttttatac agtcctccct
      421 tgtttttata tgatttcaat tttaaatttt tctgcaaaaa atatttatag taattccaca
      481 cagaaagcat cccatggaac taagatttgt ttttcaaaga cttcttgagc tagggtgttt
      541 tcaatcaaga cagatttgac ttttccttct actgtcaagt cttgctcttc attggacaag
      601 ttagccacaa ctaggaagcg acggtcgcca tccttacgta tataagcaaa gaccttatca
      661 gccgtatcaa gcaattcaaa gtcagctcga actagccagc tattctcctt gcgaatttgg
      721 accagtttct gataggtata gaaaatagaa tctggatttg ccagcgcttc ttggacattg
      781 atcatctcgt aatttggatt aaccgccaac caaggttgac ctgttgagaa accagcgttt
      841 ttgctctcgt cccattgcat aggggtacgg gcattgtcac gtccaataac acggatactg
      901 tccatgattt cttcaatcgg aacacctttt tcaagagcct cacgcgcata gttgagagat
      961 tcaatatctt ctacttgatc cagtgtttca aacggatagt tggtcatccc aatctcctca
     1021 ccttggtaga tataaggagt tcctctcata agatgaagca agattgcaaa ggctttggca
     1081 gatttttcgc ggtattcttg gtcatttccc cagattgaga caatacgagg gaggtcatgg
     1141 ttgttccaga agagggaatt ccagccgtcc tcaactccta actctgtctg ccatttgttg
     1201 aagatttctt ttaacttagc gatattcagc tctttttgat agtgccattt aggctgacct
     1261 tcctgatact gaagaccgat atgttcaaac tggaagacca tagacaattc ttgccccttt
     1321 ggatcagagt agagcttggc aatctctggc gttgctcccc aagtctcccc tactgtcaag
     1381 agatccttat ctccaaaggt cgcctgattc atttccttga gatagggatg gagcatagga
     1441 ccattattga ctaccttctc gtcaggaatt ttgccaatca tgtcaataac atccatacgg
     1501 aaaccaccaa tacccttatc aatccagaag ttcatcatct cataaatttt ctggcgaagt
     1561 ttttcatttt cccagttgag atccggctgt ttcttgctga aaaagtggag atagtattga
     1621 cctgactttt catcgtattc ccaagcagac ccactaaaga tagaatctaa atcgttaggc
     1681 tcatcccgcc agatatagta gtctcgctca gggctattag gattttcaca ggcctctaca
     1741 aaccaggcat gctcatccga ggtatgattg accaccaagt ccatgatgat acggatatca
     1801 cgcttcttag cttctgcaat cagctgatcc atgtcctcca tggttccaaa aatagccgca
     1861 atcgcttgat aatcagcaat atcgtagcca ttatcatcca tagggctgtc ataaacggga
     1921 gaaagccaaa ttgctgtgat tcctagcttg gctagatagt ccaacttact ggtaattcct
     1981 ggcaaatcgc caattccatc tccattacta tccataaaac tctttggata gacttgatag
     2041 actacggcat tatgccacca tttttcttgc atctgtttac ctcattattt tcataatcta
     2101 tagtctatga tagcactttt taaaattttg tgcaagcgtt tgcttaatct ttttaatttc
     2161 ttttttagct ccgtagtttc ctaacttcca attttttatt ataatagagt ccagaggtaa
     2221 aaaaatgaaa aaacaagctt ttagttctga acagtatttg aatttacaac gcgaccatat
     2281 tttggagcgc attaaccaat ttgacggcaa gctctactta gagtttggcg gtaaaatgtt
     2341 agaagatttc cacgctgctc gtgtccttcc tggttatgaa cctgacaaca aaatcaagct
     2401 cttgcaagaa ttgaaagagc aggttgaggt tgtgattgcc attaatgcta gcaacattga
     2461 acattccaaa gcacgtggcg acttgggcat ttcttatgac caagaagttc ttcgtttgat
     2521 tgacaaattc aatgaattag ggatttttgt tggttccgtt gtcattacac aatacgctgg
     2581 ccaacccgct gcagatgcct tcctcaacca acttgagaaa aacggaattg attcttatct
     2641 tcattatcca atcaaaggat atccgacgga tatggatcac atcatttccc cagaaggcat
     2701 gggcaaaaac gactacatca aaaccagtcg caacttgatt gtcgtaaccg ctcctggacc
     2761 cggttctgga aaattggcaa cgtgtatgtc caatatgtac cacgaccaaa tcaatggcat
     2821 caagtctggc tacgctaaat ttgaaacctt ccctgtttgg aatcttcccc ttcatcatcc
     2881 agttaacttg gcttatgaag ctgccacagc tgaccttgat gatgtcaaca tgattgaccc
     2941 cttccatctt caaacctatg gagaaaccac tgtcaactac aaccgtgata tcgaaatctt
     3001 cccagtgctc aagcgcatgt tggaacgtat tctcggaaaa tcaccatacg cttcaccgac
     3061 agatatgggt gtcaacatgg ttggtttcgc tattacagat gacgaggctg ctgtcgaagc
     3121 ttctaaacaa gaaatcatcc gccgttacta tcaaacagtt cttgacttca aagctgaaaa
     3181 agttggcgaa gctgccgtca agaaaattga gttgctcatg aacgacctcg gtatctcacc
     3241 tgcagaccgt aaggttgctg tcgttgcgcg ccaaaaagca gaagaaactg gcggaccagc
     3301 cctagctctt gaattaccaa atggtgacat tgtcactggt aaaaactcag aactctttgg
     3361 ccctacagcc gctgccttga tcaacgccat caaaaaatca gctgacatcg ctaaagaagt
     3421 aaaactaatc gagcctgaag ttgttaagcc aatccaagga cttaaaatcg atcatctcgg
     3481 tagccgcaat ccacgccttc attcaaatga aatcctgatt gcacttgcta tcacagctac
     3541 agaaaatcct gatgctgccc gcgctatgga agaactcggc aacctcaaag gaagcgaagc
     3601 ccactcaacc atcatcttga ctgatgaaga caagaatgtc cttcgtaaac tgggtatcaa
     3661 cgtaaccttt gacccatact accaatacga ccgcttatat cgtaagtaaa gatttcaacc
     3721 tctccagcct cggagaggtt ttctctctgt ctcaggagca agctttatga tataatgaga
     3781 gaagaaaact gaaaggattt accatgtcaa aagaagttat tgtcgaaagt tttgaacttg
     3841 accacaccat tgtcaaagca ccctatgttc gcttgattgg ggaagaaaca ggaccaaaag
     3901 gagacatcat ctccaattat gatattcgct tggtgcaacc aaacgaagac tctatcccta
     3961 ctgccggcct tcacactatc gagcacctct tagccaaact catccgtacc cgcattgacg
     4021 gcatgattga ctgttcacca tttggttgcc gcacaggctt ccacatgatt atgtggggac
     4081 gtcacaccag tgctaaaatc gcagctgtta tcaaggattc gctcaaggaa atcgctgaaa
     4141 ctactacttg ggaagatgtc ccagggacaa ccatcgaatc ttgcggaaac tacaaggacc
     4201 acagcctctt ctctgctaaa gaatgggcaa aactcatctt ggaacaaggg atttcagatg
     4261 atgcctttga acgtcatgtg atttaaaatc gagtagggga taatctctag cccctctcac
     4321 accaccgtac gtgccgttcg gcatacggcg gttcaactaa cttttaacgc atgtcgttca
     4381 aggtaataat ccaaacacga aaccaatcca cgtttttcaa ggactggttt tgatatagca
     4441 cgtttaagta ccgacttctg agctactata gtggattgaa actagaatag ttcacctctg
     4501 cttctaaaac attgttagaa atcgattt
//
LOCUS       DAVBDR010000090         4438 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.090, whole genome shotgun sequence.
ACCESSION   DAVBDR010000090 DAVBDR010000000
VERSION     DAVBDR010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4438)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4438)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4438
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.090"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            <1..119
                     /locus_tag="VQ540_002010"
     CDS             <1..119
                     /locus_tag="VQ540_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET2545757.1"
                     /translation="QQGFTDRLVGYSSSIALVFTTLIGMISLVQRRVLKEDD"
     gene            121..966
                     /locus_tag="VQ540_002011"
     CDS             121..966
                     /locus_tag="VQ540_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000819520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HET2545758.1"
                     /translation="MKRFKPTTILEYILLTLLAGLFLFPMVWMVVSAMKPEADVYKNL
                     TSWQAFLPSLNPADWFKPYQEVFERFSIFTYLGNSIFYAGTFAIGSIIVNALAGFAFA
                     KVNFSGKKILFGFLLALLIIPVETVLIPQFTIINSLGLVNNRLAVIIPGLASVFNIYL
                     FRNFFIAIPEEILESAKMDGASIVRIFFRIMLPMSKPAVATVGVLSFISSWNDYIWPL
                     MVLTDSSKFSMQVAITTINTTQPVYINQVMAVLTISTIPLILVYVVAQKYIVQGLGGS
                     GTGIK"
     gene            976..2295
                     /locus_tag="VQ540_002012"
     CDS             976..2295
                     /locus_tag="VQ540_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HET2545759.1"
                     /translation="MINKTFTVEKANRFIAENKHLVNTQYKPEEHFSAEIGWINDPNG
                     FVYFRGEYHLFYQFYPYDSVWGPMHWGHAKSKDLVTWEHLPVALAPDQDYDRNGCFSG
                     SAIVKDDRLWLMYTGHIEEETGVRQVQNMAFSDDGIHFEKISQNPVATGSDLPDELIA
                     ADFRDPKLFEKDGRYYSVVAAKHKDNVGCIVLLGSDNLVEWQFESIFLKGGEHQGFMW
                     ECPDYFELDGKDCLIMSPMRYQREGDSYHNINSSLLFTGKVDWREKRFIPESVQEIDH
                     GQDFYAPQTLLDDQNRRILIAWMQTWGRTLPTHDQEHKWACAMTLPRILRLEDGKLRQ
                     FPVKKGQYQIQIDKDCHYHLGNDTDYLEFGYDSNAQQVYIDRSHLIQKILGEEEQDTS
                     RRYVDIEAKELEVVLDKNSIEIFVNQGEASLTATYYLTVPAELSRID"
     gene            complement(2503..2575)
                     /locus_tag="VQ540_002013"
     tRNA            complement(2503..2575)
                     /locus_tag="VQ540_002013"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(2540..2542),aa:Lys,seq:ctt)
     gene            complement(2839..4110)
                     /locus_tag="VQ540_002014"
     CDS             complement(2839..4110)
                     /locus_tag="VQ540_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001113185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HET2545760.1"
                     /translation="MPDNLALRMRPKTIDQVIGQEHLVGPGKIIRRMVEANRLSSMIL
                     YGPPGIGKTSIASAIAGTTKYAFRTFNATVDSKKRLQEISEEAKFSGGLVLLLDEIHR
                     LDKTKQDFLLPLLESGLVIMIGATTENPFFSVTPAIRSRVQIFELEPLSNQDVKEALQ
                     IALSNPERGFDFPIELDEDALDFIATSTNGDLRSAFNSLDLAVLSTPENDEGIRHITL
                     DIMENSLQRSYITMDKDGDGHYDVLSALQKSIRGSDVDASLHYAARLIEAGDLPSLAR
                     RLTVIAYEDIGLANPEAQIHTVTALDAAQRIGFPEARILIANVVIDLALSPKSNSAYV
                     AMDKALADLKTSGHLPIPRHLRDGHYSGSKELGNAQDYLYPHNYPGNWIKQDYLPEKI
                     RNHHYFQAEDTGKYERALAQRKEAIDRLRKI"
BASE COUNT         1294 a          809 c          976 g         1359 t
ORIGIN      
        1 atcaacaagg ttttactgat cgtcttgtag gatattctag ctcaatcgct ttagtattta
       61 caacgttaat tggtatgatt agcttagtac aacgtcgcgt tctgaaggag gatgactaag
      121 atgaaacgat ttaaaccaac aacaatctta gaatatattc tgttaacttt attggcagga
      181 ctcttccttt ttcctatggt ttggatggta gtttcagcta tgaagccaga agcggatgtt
      241 tataaaaatt tgactagttg gcaagccttc ttaccaagtt taaatcccgc tgattggttt
      301 aaaccttatc aggaagtatt tgagcgcttt agtattttta catatctagg gaacagcatt
      361 ttttatgctg gaacgtttgc tattggttct attattgtca atgcactggc cggtttcgct
      421 tttgcaaaag tcaatttttc aggtaagaaa attttatttg gtttcttact tgctttactt
      481 attattccag tggaaactgt gttaattcca caatttacca ttatcaattc cttaggtttg
      541 gtcaataatc gtcttgcagt tattattcca ggattggcga gtgtatttaa tatttactta
      601 tttaggaatt tctttattgc aattccagaa gagattcttg agtctgcaaa gatggacgga
      661 gcaagtatcg ttagaatttt ctttagaatt atgcttccaa tgtctaaacc tgcagttgct
      721 acagttggtg ttttatcatt tatttcaagc tggaatgatt atatctggcc attgatggtt
      781 ttgacagatt cttctaaatt ttcaatgcag gttgcaatta caactattaa tacaactcaa
      841 ccagtttata tcaatcaggt aatggctgta ttaactattt caacgattcc gttgattttg
      901 gtctatgtag tcgctcagaa atatattgtt caaggtctgg gtggttccgg aactggaata
      961 aaataggata tacttatgat aaataaaaca tttacagtag aaaaagccaa tcgttttata
     1021 gcagaaaata aacatctcgt taatactcaa tataagcctg aagaacattt ttcagctgag
     1081 attggttgga tcaatgatcc aaatggattt gtctattttc gtggagaata ccatctcttt
     1141 tatcaattct atccatatga tagtgtttgg gggcctatgc actggggaca tgctaaaagt
     1201 aaggacttgg tgacttggga gcacttgcca gtggcacttg ctcctgacca agattatgac
     1261 cgaaatggtt gtttctcagg ctctgccatt gtcaaggatg atcgcctctg gctcatgtac
     1321 actggacata tcgaagaaga aaccggtgtc cgccaagtgc aaaatatggc attttcagat
     1381 gacgggattc actttgaaaa gatttcccaa aatccagttg caactggatc agacttgcca
     1441 gatgagttga ttgctgctga tttccgtgat ccaaaactct ttgaaaaaga tggacgctat
     1501 tactccgtag tagctgccaa acacaaggat aatgtgggct gtatcgttct actagggtcc
     1561 gataacctag tagaatggca gttcgaatcc atctttttaa aaggaggaga acaccaaggc
     1621 tttatgtggg aatgcccaga ttacttcgag ttagatggga aagattgcct tattatgtca
     1681 cccatgcgtt atcagcgtga gggagactca tatcataaca tcaactcatc gcttttgttc
     1741 acgggtaagg tagattggag agaaaaacgt tttatcccag aatcagttca agaaattgat
     1801 catggccaag acttctatgc gcctcaaaca ttgttggacg atcaaaatcg tcgtatcctg
     1861 attgcttgga tgcagacatg ggggcgtacc cttccaaccc atgaccaaga acacaaatgg
     1921 gcatgtgcca tgactttacc tagaattcta agattggaag atggcaaact aagacaattc
     1981 cctgttaaaa aaggccaata tcaaatccaa atagataaag attgtcatta ccacttagga
     2041 aatgatacag attatcttga atttggttat gacagtaatg cgcagcaagt ttacattgat
     2101 cgtagccatc ttattcaaaa aattctaggt gaagaagaac aggacactag tcgacggtat
     2161 gtagatattg aagctaaaga attggaagtt gttctagata aaaattccat cgagattttt
     2221 gtcaatcaag gtgaagcaag cttgactgca acttattact taacggtgcc agctgagcta
     2281 tcacgaattg attaaaaatt aagttatttc tcctaaagaa aaagttctct ttctaaaata
     2341 gtggaaagag gactttttgt gttttgggta tataagctta gtttatggta tttgtaaaat
     2401 tggtgttgga ttatgattta agctagtttt ctaaagaatt tgaaaaaaat tttatttaag
     2461 caaaaaaacc ttggttccaa ggcttttcct gttgtattta gatgccccct acagggatcg
     2521 aacctgtgac ccacggatta agagtccgct gctctgccag ctgagctaag gaggcaaaga
     2581 aaaagctgta ttggtgccga aacttcacgg tttgtattga acccgcgcaa ttaagcaggt
     2641 gggcaactcg ctctaactga agctgtttcc gtgtgagacg gcctacatgc tgttagaaga
     2701 cttttgtttc cctaataata caaaaaatag tcggtcaaca cttaagtgtg aagtcgtaca
     2761 ccacagcgtt tctatactta tatgatacca ctttttcaaa aaaaatcaag aggaaagtgc
     2821 aattttttga aaaggatttc agatttttcg caaacgatcg atagcttcct ttctttgagc
     2881 caaagcccgt tcatatttac cagtatcttc tgcttggaaa tagtgatgat tacgaatttt
     2941 ttctggcaga tagtcttgct tgatccaatt tccaggatag ttgtgtggat agagatagtc
     3001 ttgggcattc cccagttcct tgcttccact gtagtgccca tcacgcaggt gtcgcggaat
     3061 aggcaagtgc cctgatgttt tgaggtcagc aagtgcctta tccatagcta cataggctga
     3121 gttggatttt ggagaaaggg ccaaatcaat cacgacattg gcaatgagaa tgcgggcttc
     3181 ggggaaacca atcctttgtg cagcatccag agcagtcacg gtatgaatct gggcctcagg
     3241 attggctaag ccaatatctt cataggcgat aacagtcaag cgacgagcga gactaggcag
     3301 atccccagcc tcaatcaagc gggcagcata gtggagactg gcatccacat ctgagccacg
     3361 gatagacttt tgcagggcag atagaacatc atagtgaccg tctccatcct tgtccatagt
     3421 gatgtagctt ctctgaagac tattttccat gatgtctaag gtgatgtggc gaatgccctc
     3481 gtcattctca ggggtagaga gaacagccaa gtccagtgag ttaaaggcag agcgaaggtc
     3541 tccgtttgta gaggttgcga tgaaatccag cgcatcctca tctagttcta ttggaaaatc
     3601 aaaaccacgt tcagggttac ttagagctat ctgcagggcc tctttgacgt cttggttaga
     3661 cagaggttcc aactcgaaaa tttgaacacg gctacgaatg gcaggagtga cagagaagaa
     3721 aggattttca gtcgttgctc caatcatgat gaccagtcca ctttccaaga gaggcaagag
     3781 gaagtcttgc ttggtcttat ctagtcgatg aatttcgtct agcaatagga cgagaccacc
     3841 agaaaattta gcttcttccg agatttcttg cagtcgcttt ttactatcaa ctgtcgcatt
     3901 gaaagttcga aaggcatact tggtcgttcc agcgatggca gaggcaatac tggttttgcc
     3961 gattccagga gggccatata gaatcatgga ggacaggcgg ttggcttcca ccatgcggcg
     4021 gatgattttt ccaggtccga ccagatgctc ctgaccgatg acctggtcga tggttttagg
     4081 gcgcatgcga agcgcgagat tgtctggcat agcagtcctt tctaacgtgg atttgagtag
     4141 aatgactcat ctactatatc ttactatgtc cattctagcc tattagttgt gatatttcaa
     4201 tggttttgta ataatcaggg agtgagatag aatctttttt actatttaat ttaatgagga
     4261 gaggtatcag catgagagat ttgattttcc ttaaagctca aaataggata gttgagccta
     4321 aagaagtgga agtgctgact tgagaaataa tattgctgaa tgtcattgta tgaactataa
     4381 tgaaaagaga ggtgataagc aatggaaatg atggaccaag tcaggaaatt ttgatttt
//
LOCUS       DAVBDR010000091         4245 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.091, whole genome shotgun sequence.
ACCESSION   DAVBDR010000091 DAVBDR010000000
VERSION     DAVBDR010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4245)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4245)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4245
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.091"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            complement(<1..1288)
                     /locus_tag="VQ540_002015"
     CDS             complement(<1..1288)
                     /locus_tag="VQ540_002015"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HET2545761.1"
                     /translation="MKLQKPKGTQDILPAESAKWQYVEGFAREIFKRYNYAEVRTPIF
                     EHYEVISRSVGDTTDIVTKEMYDFYDKGDRHITLRPEGTAPVVRSYVENKLFAPEVQK
                     PSKFYYMGPMFRYERPQAGRLRQFHQIGVECFGSSNPATDVETIAMAAHFLKEIGIQG
                     VKLHLNTLGNPESRAAYRQALIDYLTPLKETLSKDSQRRLEENPLRVLDSKEKEDKVA
                     VENAPSILDFLDEESQAHFDAVRQMLENLGVDYIIDTNMVRGLDYYNHTIFEFITEIE
                     GNDLTVCAGGRYDGLVAYFGGPETAGFGFGLGVERLLLILEKQGVTLPIENALDVYIA
                     VLGEGANIKALELVQALRQQGFKAERDYLNRKLKAQFKSADVFAAKTLITLGESEVES
                     GQVTVKNNQTREEVQVSLETISQNFSEIFEKLGFYTQ"
     gene            complement(1366..2613)
                     /locus_tag="VQ540_002016"
     CDS             complement(1366..2613)
                     /locus_tag="VQ540_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter"
                     /protein_id="HET2545762.1"
                     /translation="MKLLFRNPAYRILTLSRFFNAFGVSIFNLVFIVYASTLSQASFA
                     VAMANIVMILPTLFTVFAGIRADYTRDKVKWMVYSGLFQAVLFFLAALVVQQASLFAF
                     SSLCLINVISDIISDFAGGLRMPLIKEKVAEDDLMEAYSFSQFITYISAIGGQAFGVW
                     LLALSVNNFSLVAGINACFFLVSATILFLGKSKLSLSMSSADGENLKNEKLSIKDQFL
                     TIYRNLRLVFLKSGQKNFGFMLFAVLLINSLGGALGGIYNIFFLSHSLLNFSYTEALF
                     INQFCVLVSVIISSLTGNDYFGKQSLPRLMMWETVGLSLVGLANLFNQVVLGLLFLFF
                     TLYVSGKVQPKISAMLMKNLAPEVLARTSNFLGLLFTLSIPVGTACFSLVAVWNIQLT
                     WMLFVGLSLLAIFLTILNLKNDI"
     gene            complement(2804..3654)
                     /gene="rgg"
                     /locus_tag="VQ540_002017"
                     /pseudo
     CDS             complement(2804..3654)
                     /gene="rgg"
                     /locus_tag="VQ540_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398326.1"
                     /note="Rgg, as the term is used in Streptococcus
                     pneumoniae, is the lone quorum-sensing system
                     transcriptional regulator related to proteins Rgg1, Rgg2,
                     Rgg3, and Rgg4 of Streptococcus pyogenes.; frameshifted;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system transcriptional regulator
                     Rgg"
     gene            3778..4119
                     /locus_tag="VQ540_002018"
     CDS             3778..4119
                     /locus_tag="VQ540_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003080443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HET2545763.1"
                     /translation="MRDDIKINDRALALQDQIIEKLEKVFDTDVELDVYNLGLIYEIN
                     LDETGLCKIVMTFTDTACDCAESLPIEIVAGLKQIEGIKDIKVEVTWSPAWKITRISR
                     YGRIALGLPPR"
BASE COUNT         1351 a          891 c          829 g         1174 t
ORIGIN      
        1 attgagtata aaatcctagt ttttcaaaga tttctgagaa gttttggctg attgtctcaa
       61 gtgacacttg cacttcttct cgggtttggt tgttcttgac cgtcacttgt ccgctttcga
      121 cttcgctctc tcctagggtg atgagggtct tagccgcaaa gacatcggct gacttgaact
      181 gagcttttag tttacggttg aggtaatcac gctctgcttt gaaaccttgt tggcgaagag
      241 cctgtaccaa ttccaaggcc ttgatatttg ccccttcgcc caagactgcg atatagacat
      301 ctagggcgtt ttcgataggg agggtcacac cttgcttttc aaggatgaga agcaggcgct
      361 ctacaccaag tccaaaacca aatccagcag tttcagggcc tccaaagtaa gcaaccaaac
      421 catcgtagcg accacccgca cagacggtca ggtcattgcc ctcaatctct gtgataaact
      481 cgaaaatggt gtggttgtag tagtccagac cacgcaccat attggtatcg atgatgtaat
      541 ctactccaag attttccaac atctgacgca cagcatcaaa atgagcttgg ctttcttcat
      601 caagaaagtc caagatagac ggcgcattct ctactgccac cttgtcttct ttttccttag
      661 agtccaagac acgaagagga ttttcctcca agcgacgttg gctatcctta gacaaggtct
      721 ccttgagcgg tgtcaaatag tcaatcaagg cttggcggta ggctgcacgg ctctcaggat
      781 ttccaagagt gttgaggtgc aatttgacac cttgaatacc gatttccttc aaaaaatggg
      841 ctgccatagc gattgtttcc acatcggtag ctggattgct agagccaaaa cactcaacac
      901 caatctggtg gaattggcgc aagcgccctg cctgtggacg ctcataacgg aacataggtc
      961 ccatgtagta gaacttgctt ggcttttgca cttctggggc gaaaagttta ttttccacat
     1021 aggaacggac aacgggtgca gttccttctg gacggagggt aatatgacgg tcacccttgt
     1081 cataaaaatc gtacatttcc ttggttacga tatccgttgt atctccgaca gagcgactga
     1141 taacctcgta atgctcaaaa ataggcgtgc gcacttctgc atagttgtag cgtttgaaaa
     1201 tctcacgggc aaagccctca acgtactgcc acttagcaga ctcagcaggt aaaatatcct
     1261 gcgttccttt tggtttttgt aatttcatag ggaatcctct ttaaacttaa tagtcttatt
     1321 ttaccataaa tagagggatt aaaacagtaa gaaaaaaatt aggatttaga tatcattttt
     1381 gagattaaga attgtcaaaa aaatagctag caaggaaaga ccaacaaata gcatccaagt
     1441 caactgtata ttccatacgg ctactagtga aaaacaagct gttcccacag gtatggataa
     1501 ggtaaacaat agacctaaaa aattactagt acgagctaga acctctggag ctagattttt
     1561 catgagcatg gcactaatct ttggttgaac tttaccagac acatacagag taaagaagag
     1621 aaatagcaaa ccaagcacga cttgattgaa taaattagcc aaaccaacta gactaagtcc
     1681 tacggtctcc cacatcatca atctaggcaa ggactgcttc ccaaaataat cattgcccgt
     1741 aaggctactg atgatgactg atactaaaac acagaattga ttgataaata gtgcctctgt
     1801 ataagaaaaa ttcaagagag aatggctcaa aaagaagata ttataaattc cacccaaagc
     1861 gccacccaag gaattaataa gcaagacagc aaagagcata aaaccaaagt ttttctgtcc
     1921 acttttaaga aaaacgagac gtaaatttcg gtaaattgtt aggaactggt ctttgataga
     1981 aagcttctca ttttttaagt tttcaccatc agcagatgac attgacaggc tcaatttgct
     2041 ttttcctaaa aagaggatag tggctgatac taggaaaaag caggcattga ttcccgcaac
     2101 gagagaaaaa ttgttgaccg atagagctaa gagccagact ccgaaagctt gaccaccaat
     2161 agctgaaata taggtgatga actgtgaaaa agaataagcc tccatcagat catcttcagc
     2221 tactttttcc ttaataagag gcatacgcag gccacctgca aaatcactga tgatatcact
     2281 aatgacattg atcaaacaca ggctagaaaa ggcaaagaga ctagcttgct gaacaactag
     2341 ggctgctaga aaaaatagaa ccgcctgaaa caaaccgcta tagaccatcc atttgacctt
     2401 gtccctcgtg taatctgccc gaatccctgc aaaaactgta aagagggtcg gaagaatcat
     2461 gacaatattc gccatagcaa cagcaaaaga tgcttgtgac aaggtcgatg catagacgat
     2521 aaagaccagg ttgaaaatcg aaacaccaaa agcattgaag aagcgtgata aagtcaaaat
     2581 tctataagct ggatttctaa acaatagttt catagataat ctccctcctt gttctaagtt
     2641 ctacatcaag aatagcttta gtatagcact tatgaatttg cgaaacgatt cttttgaata
     2701 tatgcaacaa acaaaatgag caaaaaaacg atagaacttt tgtaatgacc tgagagaggg
     2761 caacagttct atcgcttcaa attttttctt ggtttgcaga tattcaagaa tcgggagttt
     2821 ttctatagta ttcggcagat ttattacagc caagcatctc aaaaatacgg acagcatcct
     2881 ccatcttttt ctggccttcc ttgactctac cttgcttgct atcaaggaga ccttctgccc
     2941 acagataaac aattcggaaa taggtctcat tttccttgta gaaatgctct tcgataacac
     3001 gtttaaaata ataggcattg gtaaattctt cacactcaat actagctaaa aagccattca
     3061 atagtatagt atgaaaaagg tttcgattgc cagacatttc cattagaaaa tcggatttac
     3121 gtaccatttc tcgtacatat ctagtaaaaa gagaaacaga taaaaatgga gaactgactg
     3181 aaaataaatt gagttcatag attccccaga tctcggtaga aaacaaataa tcatgaagga
     3241 cttttccttc ctctgctgtt aagtctaccc tttcatctat gctcttcata taagacttga
     3301 taataatggc atttagaata tgtttctgtt tgttgtgaga atgggcatgc ttttatactc
     3361 cctgcgatat aagtcctcaa gaggtgctat attctttggt tccaagacat ctgtaatttc
     3421 ttttctcaac tcagaatctg tatcatactg gaaacctctt gccagaaaga ggatctcctc
     3481 cacactggca gatatatttt ccagagcaaa tagaaacttt tccaccgaaa gctcactctg
     3541 acctgtttca aaacgggaca acatagacgg cgaaaattgt cctccggttg cttgtctcag
     3601 tgagatattt cttgactctc gtaattgtct aaagactttt ccaatctgct ccatagactt
     3661 ccccttgatt ccgtattttc ttcattttat catatttttc agaaaattca tcaaaaactt
     3721 gccaaattgt cagaattatg agaaaataga ggatatttat cacgtggagg gactgctatg
     3781 agagacgata tcaaaatcaa tgaccgtgct ttggccttgc aagaccaaat tatcgaaaaa
     3841 ctagagaaag tttttgatac agatgtggaa ttggatgttt acaatctagg tctgatttat
     3901 gaaatcaatc tggatgaaac ggggctctgc aagattgtca tgaccttcac cgatactgcc
     3961 tgtgattgcg ccgaaagcct gcctattgaa atcgtggcag gtctgaaaca aatcgagggt
     4021 atcaaagata tcaaggttga agttacctgg tcgcctgctt ggaaaatcac acgaatcagt
     4081 cgctatggcc gtattgccct tggactacca cctcgttaag cagaccaatc acttttaaag
     4141 atgaaaaaag caagccgaaa atggcttgct ttttgatact caatgaaaat caaagggcaa
     4201 actagaaaac tagccgcagg ttgctcaaaa cactgttttg aagtt
//
LOCUS       DAVBDR010000092         4116 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.092, whole genome shotgun sequence.
ACCESSION   DAVBDR010000092 DAVBDR010000000
VERSION     DAVBDR010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4116)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4116)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4116
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.092"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            <1..776
                     /locus_tag="VQ540_002019"
     CDS             <1..776
                     /locus_tag="VQ540_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000603792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2545764.1"
                     /translation="DYSIVEEKLDWQSKLSKIYPNVEFIKIEKLKLILLCKYRNQIID
                     LEDDKKRLLLLKLLYLTSKQFCYDEFKGAKFGCMSFFSHYQGYMSRLDSLDSDKFVSV
                     KQRIVSSISKLVEQYSDHIINLDRTLVDSLSDTLENQLFDDWDYILSEITTYSELLAK
                     SGLLYNSLDYKIDNVKKEVAKLSDFHQSLFKIEGFSDFFDSWQFQRYRSLVNQVYEIF
                     SMLQVSSVERTVLCGALSTIVFSKSNFNYQAFFEYLKDT"
     gene            805..1713
                     /locus_tag="VQ540_002020"
     CDS             805..1713
                     /locus_tag="VQ540_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000386786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2545765.1"
                     /translation="MDYVDVILDEYGSVFLIKDHIKLKINNLELYRYFSSFGMSHLQF
                     RKEELPGKLKQFDFEKNKSDSYFSKKSSLIDFIKRNYFYDIKLYSDNPKNPIESWKNK
                     TEKIKIAKSTEILWSEVANFSSISKSPYYCLLYNLKNTENYILIISKTYFSAIQKMVS
                     YNLNNYFELEDVCCKSIVSKRELIENSININKSKMKLLNVCEGSKGYTRRVFKYNNIF
                     VGQLEFHSNIIFSEIALNELSIVKLLDSVESVLSEQLFGKLNWDNLFVVLSDDFNDYL
                     DINESQKYYSNGSLRGLELGIFMGGV"
     gene            1715..3613
                     /locus_tag="VQ540_002021"
     CDS             1715..3613
                     /locus_tag="VQ540_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YcaO-like family protein"
                     /protein_id="HET2545766.1"
                     /translation="MRIIEIVDVEDQLLQLLSAHTNIDIRAQELSTLDPDSKVDLIIY
                     LKSRRDIENINNIIIKSPNRNIIVIISAFDIIYALYFPKSTFRPCLNCLLLKLKDNNP
                     EHNLLLFLKYGTLPSKHFNLDNRLKSNLILFNEKLDPKVEEYSIEGVNTTNFTFHFSC
                     SCENSGYDMSERMADILLGEGKKLSPKNYRLKKSEHLFDFTRYLDRNFGFFHHSYDEK
                     ISEYAPLHAVEINVDAGYESGWGRTFMTEAATKSAFLESLERYCNSRNRRYKKLIRGC
                     FSDLSKKYNTLNPVDFCLSNKEYRDSSYKFHDFDSEKNYDWIFGKNITTGKICLLPSQ
                     LVFYKDFSKSEENERFVYETSNGCALGSSIEEAIFYGILEIIERDNFLLTWYLKEEVK
                     QLSWESLPSRLRIINERLKEDNCELKLFNITKEVGIPVIWALYINHNENASIRSFSAA
                     GCHINPLSAIESAIFEVITSVPTFERLIEVRNKESFIEEIQNNFSLIRDIDDHILYHA
                     HADYKNKMPFLFKNNYSEYQNEFDENRIFNTYSHATLTSDLQALIKIIEKKFGDIYVV
                     NISDKVSEKFGLYCVKVLIPGLLNMSFGHSNRRVNIERIKNYVDYRGGNVNSITLNSI
                     NHLPHPFP"
     gene            3637..>4116
                     /locus_tag="VQ540_002022"
     CDS             3637..>4116
                     /locus_tag="VQ540_002022"
                     /inference="COORDINATES: protein motif:HMM:NF025394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiopeptide-type bacteriocin biosynthesis
                     protein"
                     /protein_id="HET2545767.1"
                     /translation="MKRDWKSKHLFYHDVQQFDKLVIYLSKFMDKLVNQNQIEKYFYI
                     RYWEGGPHIRLRYLVRDTQNFETIDSMINKYAYKFWENNPPMKLLNKTDYKKIYNESI
                     DNNGKMDRKLRKNATIENIAYIPEIERYGGEEALIVSEDLFCICSQVSTALLNVVDNY
                     "
BASE COUNT         1539 a          443 c          712 g         1422 t
ORIGIN      
        1 cagattactc aatagtggaa gaaaaattag attggcaaag taaattatct aaaatttatc
       61 cgaatgttga atttataaaa attgaaaaat taaaattgat tttgttgtgt aaatatagaa
      121 atcaaattat tgacttagag gatgataaaa aaagattgtt actattgaaa ttattatatt
      181 tgacttcaaa gcaattttgc tatgatgaat ttaaaggagc gaaatttgga tgtatgtcat
      241 ttttttcaca ttatcaaggt tatatgagca gattagattc actcgactca gataaatttg
      301 tttcggttaa acagaggatt gtttcctcta tttctaaatt agttgagcaa tattcagatc
      361 atattataaa tctggataga actttagttg attctctaag tgataccctt gagaatcagc
      421 tatttgatga ttgggattat atattaagcg aaataactac atatagcgaa ttattagcaa
      481 aatcaggatt gttatataat tcgctagact ataagattga taatgtaaaa aaagaagtgg
      541 ccaagctaag tgactttcac caatctttat ttaaaattga aggattttca gatttttttg
      601 atagttggca atttcaaaga tataggtctc tcgtgaacca agtttatgaa attttttcaa
      661 tgttacaagt aagtagtgta gaaagaactg tgttgtgcgg agctctaagt actattgtct
      721 ttagtaagtc aaattttaac tatcaagctt tttttgagta tctaaaagat acgtagaatt
      781 cgattttaaa ggaggctgaa atatatggat tatgtagatg taatattgga tgagtatggg
      841 agtgtttttc tgataaagga tcacataaaa ctaaaaatta ataatctaga actatatcgg
      901 tattttagta gctttggaat gagtcatctt caatttagaa aagaagagct tccaggaaaa
      961 ttaaagcagt ttgattttga aaaaaataaa agtgacagtt atttttctaa gaaaagtagt
     1021 ctgattgatt ttattaagag aaattatttt tatgatatta agttatattc tgataatccg
     1081 aaaaatccga tagagtcttg gaaaaataag acagaaaaaa ttaagattgc taaaagtaca
     1141 gaaattcttt ggagtgaagt agcaaatttt tcgtcaattt ctaaatctcc ttactattgc
     1201 ttgttatata atttaaagaa tactgaaaat tacatattga taatcagtaa gacatatttt
     1261 tcagccatcc aaaaaatggt ttcgtataat ctaaataatt attttgaatt agaagatgtt
     1321 tgttgtaaaa gcatagtgag caagcgagaa ttgatagaaa attcaattaa tattaacaaa
     1381 agcaaaatga aactgctaaa tgtttgcgaa ggtagtaaag gttacacaag aagagtattt
     1441 aagtacaata atatttttgt gggacaattg gaatttcact ctaacataat cttttcagaa
     1501 attgctttaa atgaattaag tattgttaag cttttagatt ctgttgaaag tgttttatct
     1561 gagcaactat ttggaaaatt aaattgggat aatttatttg ttgttttatc agatgatttt
     1621 aatgattatc tggatataaa tgaatctcaa aaatactact caaatggttc tttgagagga
     1681 ctggagcttg gaatctttat gggaggggtt taaaatgaga ataattgaaa ttgttgatgt
     1741 tgaggaccaa cttttacaac ttttaagtgc acataccaat attgatatta gagcacaaga
     1801 gttatcaaca cttgacccag attcaaaagt tgatttgatc atatacttga aatctcgacg
     1861 tgatattgaa aacataaata atattattat taaatcacct aacaggaata tcattgttat
     1921 aataagtgct tttgatatta tatatgcatt gtattttcca aaatcaacat ttagaccttg
     1981 tttgaactgt ctattattaa aacttaaaga taacaaccct gagcataatc tattattatt
     2041 cctgaaatac ggaacattac ctagtaaaca ttttaatctt gataataggt taaaatcaaa
     2101 tttaatacta tttaatgaga agttagaccc taaggtagag gagtatagta ttgagggggt
     2161 aaatactaca aattttactt tccattttag ttgtagctgt gaaaatagtg gttacgatat
     2221 gtcggaaaga atggcagata ttctacttgg tgaaggaaaa aaattatctc ctaaaaatta
     2281 tcgtttaaaa aagagtgagc atctattcga ttttactaga tatctagata gaaattttgg
     2341 attttttcat cattcatatg atgaaaaaat ctccgaatat gcgcctctcc atgcagtaga
     2401 gattaatgtt gatgctggtt acgagtcagg ctggggaagg acttttatga cagaggctgc
     2461 aacaaaatct gcttttttag agtcattaga gagatactgc aactctagaa atagacgcta
     2521 taaaaaatta attagagggt gtttttctga tttatctaaa aagtacaata cattaaatcc
     2581 tgttgatttt tgtctttcta ataaagaata tagagatagt tcctataaat ttcatgattt
     2641 tgattctgag aaaaattatg attggatatt tggtaaaaat ataactaccg gaaaaatttg
     2701 cttattgccc tcgcaactag tattttataa agactttagt aaaagcgaag aaaatgaaag
     2761 gtttgtttat gaaacatcaa atggatgtgc tttggggagt agtattgagg aagctatttt
     2821 ttatgggatt ttagagatta ttgaaagaga taatttttta cttacatggt atttaaaaga
     2881 agaagtaaaa caattatcat gggaatcttt accatctcgc ctacgtatta ttaatgaaag
     2941 actaaaagaa gataactgtg agctcaaact ttttaatata actaaagaag tgggcatacc
     3001 agtaatttgg gcattgtata taaatcataa tgaaaatgct agtattcgaa gtttttcagc
     3061 tgcaggctgt catattaatc ctttaagtgc aattgaatca gcaatttttg aagtaataac
     3121 ttctgtgcca acttttgaaa gattaattga agttagaaat aaagagtcat ttattgagga
     3181 aattcagaat aatttttctt taatacgaga tattgacgat catatattgt atcatgctca
     3241 tgcggattat aaaaataaaa tgcccttttt atttaaaaat aattatagtg aatatcaaaa
     3301 tgaatttgat gagaatagaa tttttaatac ttattcacat gcaacgctta catcagattt
     3361 acaggcacta ataaaaatta ttgaaaaaaa atttggagat atatatgtag tgaatataag
     3421 tgataaagtt tccgaaaaat ttggacttta ttgtgttaaa gtgttgattc ctggacttct
     3481 taatatgtca tttggacatt caaatcggcg tgtaaatata gagaggataa aaaattatgt
     3541 agattataga gggggaaatg taaatagtat tacattgaat tccataaacc atcttcccca
     3601 tccatttcca taagattata tataaaggaa taataaatga aaagagattg gaaatcaaag
     3661 catttatttt atcatgatgt tcaacaattt gataaattgg taatctattt atcaaaattt
     3721 atggataaat tagttaatca gaatcagatt gaaaaatatt tctatattcg ttattgggaa
     3781 ggggggcctc atattcgatt aagatatttg gtgagggata cacaaaattt tgaaacaatt
     3841 gatagtatga taaataagta tgcttataaa ttttgggaaa ataatcctcc aatgaagtta
     3901 ttaaataaga ccgattataa gaaaatttat aatgagagta ttgataacaa cggaaagatg
     3961 gatagaaaat tgaggaaaaa tgcgactatt gaaaacattg cctatatacc ggaaatagag
     4021 agatatggcg gggaagaagc tctgatagta agcgaagatc tattttgtat ctgtagtcag
     4081 gtttcaactg cgttacttaa tgtggtagat aactat
//
LOCUS       DAVBDR010000093         4046 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.093, whole genome shotgun sequence.
ACCESSION   DAVBDR010000093 DAVBDR010000000
VERSION     DAVBDR010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4046)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4046)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4046
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.093"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            complement(<1..370)
                     /locus_tag="VQ540_002023"
     CDS             complement(<1..370)
                     /locus_tag="VQ540_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000927991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2545768.1"
                     /translation="MLLVLVSLVHSFGSVSIIAHTIHQKFNLKVPNYRQEEDWARMGL
                     PITRKEISNWHIKASQYYLESLYKLLREKLLEQPLLHADETSYRVLESDSHLTYYWTF
                     LSGKAENQAITLYHHDQRRSG"
     gene            complement(446..1297)
                     /gene="rfbD"
                     /locus_tag="VQ540_002024"
                     /pseudo
     CDS             complement(446..1297)
                     /gene="rfbD"
                     /locus_tag="VQ540_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647909.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
     gene            complement(1363..2412)
                     /gene="rfbB"
                     /locus_tag="VQ540_002025"
     CDS             complement(1363..2412)
                     /gene="rfbB"
                     /locus_tag="VQ540_002025"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000141505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HET2545769.1"
                     /translation="MTEYKNIIVTGGAGFIGSNFVHYVYENFPDVHVTVLDKLTYAGN
                     RANIEEILGNRVELVVGDIADAELVDKLVAQADAIVHYAAESHNDNSLNDPSPFIHTN
                     FIGIYTLLEAARKYDIRFHHVSTDEVYGDLPLREDLPGHGEGPGEKFTAETKYNPSSP
                     YSSTKAASDLIVKAWVRSFGVKATISNCSNNYGPYQHIEKFIPRQITNILSGIKPKLY
                     GEGKNVRDWIHTNDHSSGVWTILTKGQIGETYLIGADGEKNNKEVLELILKEMGQATD
                     AYDHVTDRAGHDLRYAIDASKLRDELGWKPEFTNFEAGLKATIKWYTDNQEWWKAEKE
                     AVEANYAKTQEIITV"
     gene            complement(2422..3018)
                     /locus_tag="VQ540_002026"
     CDS             complement(2422..3018)
                     /locus_tag="VQ540_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000131470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase family
                     protein"
                     /protein_id="HET2545770.1"
                     /translation="MTDNFFGKTLAARKVEAIPGMLEFDIPVHGDNRGWFKENFQKEK
                     VLPLGFPESFFAEGKLQNNVSFSRKNVLRGLHAEPWDKYISVADGGKVLGSWVDLREG
                     ETFGNTYQTVIDASKGIFVPRGVANGFQVLSDTVSYSYLVNDYWALELKPKYAFVNYA
                     DPSLGIEWENLEEADVSEADKHHPLLKDVKPLKKEDLE"
     gene            complement(3019..3876)
                     /gene="rfbA"
                     /locus_tag="VQ540_002027"
     CDS             complement(3019..3876)
                     /gene="rfbA"
                     /locus_tag="VQ540_002027"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000676139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HET2545771.1"
                     /translation="MKGIILAGGSGTRLYPLTRAASKQLMPVYDKPMIYYPLSTLMLA
                     GIRDILIISTPQDLHRFQELLQDGSEFGIKLSYAEQPSTDGLAIGEEFISDDSVALIL
                     GDNIYHGPGLSTMLQKAAKKEKGATVFGYQVKDPERFGVVEFDTDMNAISIEEKPEYP
                     RSNYAVTGLYFYDNDVVEIAKSIKPSPRGELEITDVNKAYLDRGDLSVELMGRGFAWL
                     NTGTHESLLEASQYIETVQRMQNVQVANLEEIAYRMGYISREDVLALAQPLKKNEYGQ
                     YLLRLIGEA"
BASE COUNT         1136 a          927 c          734 g         1249 t
ORIGIN      
        1 aaccactccg acgctgatca tggtggtaca gcgtgattgc ttgattctca gctttcccag
       61 acaaaaaagt ccaatagtag gtcagatggc tatcactctc tagaacccga taagaggttt
      121 catccgcatg aagaagaggt tgttctaaca acttttctcg taaaagctta taaagggact
      181 ctaaatagta ttgacttgcc ttgatatgcc aattagagat ttccttacgt gtgattggta
      241 aacccatcct agcccaatct tcttcttggc gataattggg taccttcaga ttaaacttct
      301 gatggatggt gtgagcgata atagaaactg agccaaagct atgcaccaaa gagaccagca
      361 ccaacaacaa gataattgta catcttaagc tcctttggag ttcattatct gcctctttta
      421 ttagactaga aaatcattct actacttatc tcacttcttg tttgtaaaat tcttgcaatg
      481 catcttgcca agttggaata acaaatccag tagctttggc tttggccagg ctcatcgttg
      541 agtttagcgg acgttgagct ttggctggaa attgactgga atctactggc ttgacttcga
      601 catctgtatc tttcaaaatt tcaactgcaa aatcatacca tgttgtgtct tctgtcgcat
      661 catttgacaa atgataataa ccaaattcct tacgattttc agctaggtag atcatgaatt
      721 cagccaaggt acgagtccaa gtcggacgac cgtactggtc atttacaact gttaaagtct
      781 tatgagtttt cgcaagattt tgcatggtaa aaacgaagtt tttgccataa tttccaaata
      841 cccaggcagt acggataata tagaaattag acacatgctt ctcaactaac tcttccccca
      901 tacgcttagt gcgtccatat tctgtctgtg gatctggtcg gtcatcaact tcccactctt
      961 gtccaactgg tttcttaccg tcaaagacct agtccgtaga aatataaact agagttgcac
     1021 catgcttttc agatgctttt gcgacatttt ttgtccccat cacattgatg gcgaagtcca
     1081 actcttttcc ttcatcctct gctgcatcaa cagcggtgta ggctgcacaa tggtagacta
     1141 aagtcggttt cacctcttca aaaactttct caaccatttc ttcattggta atgtccatct
     1201 cagccacatc tactgccacg tattcttcat tacgttcatc caataaatag cgaagttccg
     1261 ttcctaattg gccatttgcc cctgtaatta aaatcatctc tagacctttc taatatgtaa
     1321 ctcttcccaa tatagcaata aaaagcagcg atttcctgct ttttatactg taataatctc
     1381 ctgagtctta gcataattgg cttcaacagc ttctttttct gctttccacc attcttggtt
     1441 atctgtatac cacttgattg ttgccttgag cccagcttca aagttggtaa attcaggttt
     1501 ccaccccaac tcatcacgga gcttgctggc atcaatcgca tagcgaaggt catgtcctgc
     1561 acggtcagtc acatgatcat aggcatccgt agcttgtccc atttccttaa ggataagttc
     1621 caaaacttcc ttattgttct tctcaccatc agccccaatc aagtaggttt caccgatttg
     1681 cccttttgtc aagattgtcc aaactcctga agaatggtca ttggtatgaa tccagtcacg
     1741 aacgttctta ccttcaccgt aaagttttgg cttaattcca cttaggatgt tagtaatctg
     1801 acgtgggatg aatttttcga tatgttgata aggaccgtag ttatttgaac agttggaaat
     1861 cgttgccttg actccaaaag aacgcaccca ggctttgaca atcaagtctg atgcggcctt
     1921 ggttgatgag tacggagagc ttgggttgta ttttgtttca gcagtaaatt tctcacctgg
     1981 tccttcacca tgacctggca aatcttctcg taaagggaga tccccataaa cttcatctgt
     2041 cgatacatgg tggaagcgaa tatcatactt acgagcagct tctaaaagag tatagattcc
     2101 aatgaagtta gtatgaataa atggcgatgg atcattgagc gaattatcat tgtggctttc
     2161 cgctgcataa tgaacgatag catctgcttg agcaaccaac ttgtctacca actccgcatc
     2221 agcaatgtca ccaacaacta actcaacacg attgcctaaa atttcctcaa tattcgcgcg
     2281 gtttccagca taagtcaact tatctaggac tgtcacgtga acatctggaa agttctcgta
     2341 aacataatgg acaaagttag aaccgataaa gccagctcca cctgtcacga taatattttt
     2401 gtattcagtc atattctttc cttattccaa atcttctttt ttcaaaggct tcacgtcctt
     2461 aagtagggga tgatgtttgt ctgcttcaga tacgtctgct tcttccagat tttcccattc
     2521 aataccaagg cttggatcag cgtagttcac aaaggcatac ttgggtttga gttcaagagc
     2581 ccagtaatca ttgaccagat agctatatga cactgtatct gataaaactt ggaagccatt
     2641 agctacgcct cgaggaacaa agattccctt gcttgcatca attactgtct gataggtatt
     2701 cccaaaggtt tcaccctcgc gtagatcaac ccaagaaccc agaactttcc ctccatctgc
     2761 tacagagatg tacttatccc aaggctctgc gtggaggcct cgaaggacat ttttacgtga
     2821 gaaggataca ttgttttgca attttccttc tgcaaagaaa gactctggaa atccaagtgg
     2881 aagcactttt tccttttgga aattttcttt aaaccagcca cgattatctc catgaacggg
     2941 gatatcaaac tccaacatgc ctggaatagc ttcaaccttg cgtgccgcaa gcgtcttacc
     3001 gaaaaaatta tctgtcatct atgcttctcc aatcaaacgg agcagatact gtccgtattc
     3061 atttttctta agtggttggg ctaaggccaa tacatcttct cgactgatat agcccatacg
     3121 gtaagcaatt tcttctaagt ttgctacctg aacattttgc atccgttgca ctgtttcgat
     3181 gtactgtgaa gcctctagta aactttcatg agttccagta ttcagccaag caaagccacg
     3241 tcccataagc tcaacagaca aatcaccacg atctaggtaa gccttgttta catctgtaat
     3301 ttccagttca ccacgagggc ttggtttaat actcttggca atttcgacaa catcgttatc
     3361 atagaaatac agtcctgtca ctgcatagtt ggagcgagga tactccggtt tttcttctat
     3421 ggaaatagca ttcatgtctg tatcaaactc aaccacacca aaacgctctg gatccttcac
     3481 ttggtagcca aaaacagtcg cacctttctc tttcttggct gctttttgaa gcattgtgct
     3541 cagaccagga ccatggtaga tattgtcgcc taaaatcaag gcaacgctat cgtcagaaat
     3601 aaactcttcc ccaattgcca aaccatctgt acttggttgc tctgcataag aaagtttgat
     3661 cccaaactca gatccgtctt gaagaagctc ttgaaatcga tgtaaatcct gtggagtgga
     3721 aataatcaaa atatccctaa tcccagccaa catcaatgtt gaaagtgggt agtaaatcat
     3781 cggtttatca taaaccggca taagttgttt tgacgcagcg cgagtcaaag gatataaacg
     3841 tgtccccgaa ccacctgcta gaataatacc tttcatagta gggtaccttt ctttgttatt
     3901 ttagagtcaa ttactattaa ttgtgtactg ctctaaaaag aaaacaatca tcccatgttt
     3961 tatatggctc tataatattt gtagtgggta aatccactat agatattatg gagcctattt
     4021 tattgtagaa aaaaagtccc ataaga
//
LOCUS       DAVBDR010000094         3395 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.094, whole genome shotgun sequence.
ACCESSION   DAVBDR010000094 DAVBDR010000000
VERSION     DAVBDR010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3395)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3395)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3395
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.094"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            complement(216..827)
                     /gene="rpsD"
                     /locus_tag="VQ540_002028"
     CDS             complement(216..827)
                     /gene="rpsD"
                     /locus_tag="VQ540_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HET2545772.1"
                     /translation="MSRYTGPSWKQARRLGLSLTGTGKELARRNYVPGQHGPNNRSKL
                     SEYGLQLAEKQKLRFTYGVGEKQFRNLFVQATKIKGGILGFNFMLLLERRLDNVVYRL
                     GLATTRRQARQFVNHGHILVDGKRVDIPSYRVTPGQVISVREKSLKVPAILEAVEATL
                     GRPAFVSFDAEKLEGSLTRLPERDEINPEINEALVVEFYNKML"
     gene            complement(1022..2074)
                     /locus_tag="VQ540_002029"
     CDS             complement(1022..2074)
                     /locus_tag="VQ540_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000769768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HET2545773.1"
                     /translation="MKLKSYILVGYIISTLLTILVVFWAVQKMLIAKGEIYFLLGMTI
                     VASLVGAGISLFLLLPVFTSLGKLKEHAKRVAAKDFPSNLEVQGPVEFQQLGQTFNEM
                     SHDLQVSFDSLEESEREKGLMIAQLSHDIKTPITSIQATVEGILDGIIKESEQAHYLA
                     TIGRQTERLNKLVEELNFLTLNTARNQVETTSKDSIFLDKLLIECMSEFQFLIEQERR
                     DVHLQVIPESARIEGDYAKLSRILVNLVDNAFKYSAPGTKLEVVTKLEKGQLSISVTD
                     EGQGIAPEDLENIFKRLYRVETSRNMKTGGHGLGLAIARELAHQLGGEITVSSQYGLG
                     STFTLVLNLSGSENKA"
     gene            complement(2071..2769)
                     /locus_tag="VQ540_002030"
     CDS             complement(2071..2769)
                     /locus_tag="VQ540_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000520636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET2545774.1"
                     /translation="MGKTILLVDDEVEITDIHQRYLIQAGYQVLVAHDGLEALELFKK
                     KPIDLIITDVMMPRMDGYDLISEVQYLSPEQPFLFITAKTSEQDKIYGLSLGADDFIA
                     KPFSPRELVLRVHNILRRLHRGGETELISLGNLKMNHSSHEVQIGEEMLDLTVKSFEL
                     LWILASNPERVFSKTDLYEKIWKEDYVDDTNTLNVHIHALRQELAKYSSDQTPTIKTV
                     WGLGYKIEKPRGQT"
     gene            complement(2936..>3395)
                     /locus_tag="VQ540_002031"
     CDS             complement(2936..>3395)
                     /locus_tag="VQ540_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="fibronectin-binding SSURE repeat-containing
                     protein"
                     /protein_id="HET2545775.1"
                     /translation="ALIDQFRANGTQTYSATVNVYGNKDGKPDLDNIVATKKVTININ
                     VKETSDTANGSLSPSNSGSGVTPMNHNHATGTTDSMPADTMTSSTNTMAGENMAASAN
                     KMSDTMMSEDKAMLPNTGETQTSMASIGFLGLALAGLLGGLGLKNKKEEN"
BASE COUNT          941 a          758 c          656 g         1040 t
ORIGIN      
        1 ttttttacga aaatctattg aatatgccat aaaaggatta taccacattg tgtactattt
       61 ttggttcatt ttactatatc actttggact atatcggtct agttatgtct aaacgattat
      121 agctggatac taagagaaat caaaaaagca ctaagggaga acgtcccaaa gtgcttaata
      181 tcaaggcctc aaagcctgtc ttattcaata aaatattaca acatcttgtt gtagaattca
      241 acgacaagtg cttcgttgat ttctgggttg atttcgtcgc gttctggcaa gcgagtcaat
      301 gaaccttcca atttttcagc gtcgaatgat acgaatgctg gacgtccaag agtagcttct
      361 actgcttcaa ggattgctgg aactttcaat gatttttcac gaactgagat cacttgacct
      421 ggagttacgc ggtatgatgg gatatcaacg cgtttcccgt caacaaggat gtgaccgtgg
      481 tttacgaatt gacgagcttg acgacgagta gtcgcgagac caagacggta aacaacgtta
      541 tccaaacgac gttccaaaag aagcataaag ttgaaaccta ggattccgcc tttgattttt
      601 gtagcttgta cgaacaagtt acggaattgt ttttcaccta caccgtaagt gaaacgaagt
      661 ttttgttttt cagccaattg caaaccgtat tctgacaatt tagaacggtt gtttggtccg
      721 tgttgtcctg gtacgtagtt acgacgtgcc aattctttac ctgtacctgt aagtgaaagg
      781 ccaaggcgac gagcttgttt ccaagatggt cctgtataac gtgacatatg aatgtcctcc
      841 tgatataaat aatatttcgg tggaaatagt cacttagaaa gccctgattc gtgcagatgc
      901 ccttcgccta aacagccaag gttacttgtc ataagacacc tgttgacgag cttcatgctt
      961 tcctgctgat atttcacaca aaatccattt taccatgaat agctggattt gtaaaggggt
     1021 tttaggcttt attttcacta ccagagagat tgagaacgag ggtaaaggta cttcctagac
     1081 cgtactggct gctgactgtg atttccccac ccaattgatg ggccaattca cgcgcaatcg
     1141 caagtcctaa tccatgacca cctgtcttca tgttacgcga agtttcgaca cgataaaggc
     1201 gtttgaaaat attttccaaa tcctctgggg caatgccctg cccttcatcg gtcacactga
     1261 ttgaaagctg gcccttctcc agcttagtca ccacttccag cttggttcct ggagcagaat
     1321 atttaaaagc gttatcgacc agattcacca agatacgaga aagcttagca taatctccct
     1381 caatccgggc agactctggg attacctgca agtggacatc tcttctctcc tgctcaatca
     1441 aaaactgaaa ttcactcatg cactcaatta agagcttgtc cagaaaaata ctgtctttac
     1501 tggtagtttc cacctgattt ctagctgtgt ttagggtcaa aaaattcaac tcctcaacca
     1561 gtttattgag cctctccgtc tggcgtccaa tggttgctag ataatgagct tgctccgact
     1621 ccttgataat cccatccaaa atcccttcta ccgtcgcttg gatcgaagtg ataggggtct
     1681 taatatcatg cgacaactgg gcaatcatca agcccttttc tcgttcgctt tcttccaagg
     1741 aatcaaagct tacctgcaaa tcatgggaca tctcattaaa agtttgccct aattgctgaa
     1801 attctacagg accttgaacc tccaaatttg aaggaaaatc cttggccgct acccgcttgg
     1861 catgctcctt gagtttgccc aacgacgtaa agactggcaa taggagaaag agactaatcc
     1921 cagcaccgac aaggctggca acgatggtca tcccaagcaa aaagtaaatc tcgcctttcg
     1981 caatcagcat tttttgaaca gcccaaaaaa caaccaaaat ggttaagagg gttgaaataa
     2041 tatatccaac caaaatataa ctttttagtt tcatgtttgt cctctcggtt tctctatctt
     2101 atatcccaac ccccaaactg tcttaatagt gggcgtttgg tcactactat attttgccag
     2161 ctcctgtcga agagcatgga tatgcacatt caaggtattg gtgtcatcca cgtagtcttc
     2221 tttccagatc ttttcataga ggtctgtctt ggagaaaact cgctctggat tgctagctaa
     2281 aatccacagc aattcaaatg atttaacagt taaatccagc atttcttctc ctatttgaac
     2341 ttcatgacta ctatgattca tttttagatt gccaagggaa atcagctctg tttcgccccc
     2401 acgatgaagg cggcgcaaaa tattgtggac acgcaaaacc agctcacgtg ggctaaaagg
     2461 cttagcaata aaatcatctg ctcccaagct caggccgtaa atcttgtcct gttcactggt
     2521 cttagcagta ataaatagga aaggctgctc tggtgataag tattgaacct cactgattaa
     2581 atcataacca tccatccgag gcatcataac atctgtgata atcaaatcaa tcggtttttt
     2641 cttgaacagc tctagcgctt ccagtccatc atgggctacc aagacctgat aacctgcctg
     2701 aattaagtat ctctgatgaa tatctgtgat ttctacctcg tcgtcaacga gtaaaattgt
     2761 ctttcccatc tgtctctcct ttgataaaaa cagtgctata ctgctttaag tataacacta
     2821 tttttattgt tttacgatga ttttaatctg ctattgaaag aaagtcctga ttgctgattg
     2881 agttgttaaa ctaatcttag tcagcccact atccatcatt tatttcctta gctgattagt
     2941 tttcttcttt tttgtttttc aaacctagac caccgagtaa acctgcaagc gcaagcccaa
     3001 ggaaaccaat acttgccatt gatgtttgag tctcaccagt atttggtagc atagctttat
     3061 cctctgacat catcgtatca gacatcttgt tagcagaagc agccatgttt tcacctgcca
     3121 tcgtgttggt agaacttgtc atggtgtcag caggcatgct atctgtagta cctgtagcat
     3181 gattgtgatt catcggagtc acgccagaac cagagttaga aggtgataat gaaccatttg
     3241 ctgtgtctga tgtttcttta acatttatgt taatagtgac ttttttagtt gctacgatgt
     3301 tgtccaagtc tggtttaccg tctttgttac catagacatt gactgtagcg ctgtaagttt
     3361 gagtaccatt tgctcggaac tggtcaatga gcgct
//
LOCUS       DAVBDR010000095         3160 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.095, whole genome shotgun sequence.
ACCESSION   DAVBDR010000095 DAVBDR010000000
VERSION     DAVBDR010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3160)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3160)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3160
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.095"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            <1..314
                     /locus_tag="VQ540_002032"
     CDS             <1..314
                     /locus_tag="VQ540_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2545776.1"
                     /translation="KKGQFDELVSNLNLSEQEQLDLLQQYKEEHPRRAKRGIKSAIIK
                     KVARFLAAKVGQKSVVEITDYLFEWQDNLEAGAENYLVQYGWDRNIAHWTIKTVSFIF
                     L"
     gene            801..1763
                     /locus_tag="VQ540_002033"
     CDS             801..1763
                     /locus_tag="VQ540_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /protein_id="HET2545777.1"
                     /translation="MEKWENQDKILLDKNKRGKDRNWRGRKLLSLKLADIFKELGYRE
                     TLIERVETCGDTLRFIRREDGSLRLYQAYFCKNKLCPMCNWRRSMKYSYQTSQIVDEA
                     IKEQPKGRFLFLTLTVKNVPGKELNATISQLTQSFDRLFRRAKVKKNLIGFLRSVEVT
                     HNQEEETYHPHIHVLMMVKSSYFSGAGDNYVSQEEWGRMWEQSLKVDYVPMVDIRSVK
                     EIGKGLKGAILETAKYPIKPIKLDVENKQVVGDLYNGLYRKRQLGYGGLFKEIRKRLQ
                     LSNVENGDLVYTSDDNDEMLKGTKIVAIWNATKQNYFVKNKGWN"
     gene            2236..2535
                     /locus_tag="VQ540_002034"
     CDS             2236..2535
                     /locus_tag="VQ540_002034"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2545778.1"
                     /translation="MMNIAYKNRDLSDEEFKEEAHQFRDKEIKILEEKLKELNISCKV
                     VGINSIKDMNEYKEIMENVNQAKEELKRIDELIAVRSSRIDFLEDKTLRITGNQR"
     gene            2998..>3160
                     /locus_tag="VQ540_002035"
     CDS             2998..>3160
                     /locus_tag="VQ540_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2545779.1"
                     /translation="MNKKFLKCGTLFLISCSILGSTIPAVTVFSDEVTITYNSENNSE
                     KNELYNQLSA"
BASE COUNT         1115 a          365 c          653 g         1027 t
ORIGIN      
        1 aaaaaaaagg acagtttgat gagttggtaa gtaatttgaa tttgagcgaa caagaacaat
       61 tagacttgtt gcagcagtat aaagaggaac atcctcggcg agctaaaagg gggataaaat
      121 cagctataat aaaaaaagtc gctcgtttcc ttgctgctaa agtaggacaa aaaagtgtag
      181 tggagataac tgactattta tttgaatggc aagacaattt agaagctgga gcggagaatt
      241 atcttgtaca atatggttgg gatagaaata ttgctcactg gacaataaag acagttagct
      301 ttattttctt ataagtcatt atgaataaag cttggttatt ttggagtgtc atagtcttat
      361 atttttttat aaagtttttt gataaagttt tagatataaa gctttttggt tctattcaaa
      421 tatggctaga taatctccct attccgatga aaatactgtt aacaatagca ttagttttgt
      481 ttttattcat tgtatttcca tatagaggaa aacggtaaaa acggtaatta gatatataaa
      541 aggagctgaa agctccgtaa aaaacctact cgaagagtag gttttttctt atcttgatac
      601 tagtaggaaa taactctcat gctattttta gggtttcgac agggtctaaa cccttgatac
      661 tactgacttt ttaggtaaaa aaatgccctt gacttttttc aacggatctt ttataattta
      721 gttgttcaga aaaaattata aaaagagaaa aaaggcaaag gtatttttgt atttctttgt
      781 aattacaggt aaattataac atggagaagt gggaaaatca agataaaatt cttttagata
      841 aaaataaaag aggcaaggat agaaactggc gaggacgaaa attattaagt ttgaaattgg
      901 cagatatttt taaagagtta ggttataggg aaaccttgat agaacgcgtt gagacttgtg
      961 gagatactct tcgatttatt cgtcgagaag atgggagttt gcgtttatat caagcctatt
     1021 tttgtaagaa taaattgtgt cctatgtgta attggagacg gtcaatgaaa tattcttatc
     1081 aaacatctca gatagttgat gaagcaatta aagaacaacc aaaagggcgt tttcttttct
     1141 tgactttgac tgtgaaaaat gttccaggta aagaattgaa cgcgacaatt agccagctaa
     1201 ctcagtcctt tgaccgtctt tttagacggg caaaggtaaa gaaaaatcta atcgggtttt
     1261 tacgttcggt tgaggtgact cataatcaag aagaagagac ctatcaccct catatccatg
     1321 ttttgatgat ggttaagtct agctatttta gtggggctgg agataattat gtatctcaag
     1381 aagaatgggg gcggatgtgg gaacagtcgc ttaaggttga ctatgtgcca atggttgata
     1441 ttcggtcagt taaagaaata ggaaaaggtc ttaaaggggc aattcttgaa acggcaaaat
     1501 atccaattaa gccgattaag ttagatgttg aaaacaagca agttgttggt gatttgtata
     1561 atgggttata tcgtaaacgg caattgggtt acggtggatt gtttaaagaa attcggaaga
     1621 gattgcaact gtctaatgtc gaaaatggag atctggttta tacttctgat gacaatgatg
     1681 aaatgttaaa aggtacaaaa atagtcgcga tttggaatgc gactaaacaa aactattttg
     1741 taaaaaataa gggttggaat taaagtatca actcttttat tataacataa aaaagagtaa
     1801 aatagacttg atttttttga gtttagatgt atattgaagg tgtgaaaatt aaaaagatag
     1861 ctatgttttt tctgggtata cttgttgggg tatttattgt tctatttttt agaaattatt
     1921 ttgttttact tttggaatat atttttggtt aaaaagcacc ctctaaaaag ggtgcttttt
     1981 gtgcggttat tcgcacgaaa gttctctgca agagttcctc ggaagagcgt ttgtattttg
     2041 attgtacgtc aaaactataa aaacatttac tctttgtcaa agagtagcag aaaagctaga
     2101 ataaaattaa aaattttatt ctagctaata gtgcaagtaa tagcttttgt agcttgcctc
     2161 ttgtccgtta ttcagacaag aggcaggagt ttgtatttgt tctaaatgag tatttcattt
     2221 agaacaaata catcgatgat gaacattgct tacaagaata gagatttgag tgatgaagaa
     2281 tttaaagaag aagctcatca gtttagagat aaagagataa aaatactcga agaaaaatta
     2341 aaggaactta atatttcttg taaggttgtt ggaataaata gtataaaaga tatgaacgag
     2401 tataaagaga ttatggaaaa tgttaatcaa gcaaaagagg aattaaagag aatagatgaa
     2461 ttaatagccg tcaggagctc cagaattgat tttttagagg ataaaaccct tagaattaca
     2521 ggaaaccaaa gatgagctta aaaacgaaat ggagagccta aaaagagatt tatctttttt
     2581 tagaaacgaa aatactcgac tgaaaaatgt agtttcagat tgtatcaagg tagtattttt
     2641 ggggtatttt tagtagaaag tatattgtaa tttctgagcg atttatgccg tgaaagctac
     2701 ttgaccgtaa gctagatcaa agtacgctag tcagggacga gccgaaaggc tgtagcgttt
     2761 cggagcggca cggacaaagt acgtcgacct aggttacttg cggtcaagta gaccatggaa
     2821 taaaacaagc gggtatgata taaaaaagtt atcggcaaac cgaaatatag acttgttttt
     2881 ttgtttataa aaatgtatta ttatattgag aataagattg tttaatttat ttagagagga
     2941 gtgtaagttg atcagtaaac gattttaatt ctgcctttaa ataacaagga gtttgttatg
     3001 aataaaaaat ttttgaaatg tggtacttta tttttgattt cttgttctat tttaggaagt
     3061 actattcctg cagttacagt attttctgat gaagtaacaa ttacttataa ttcagagaat
     3121 aattcagaaa aaaatgaatt atataatcaa ctttctgctg
//
LOCUS       DAVBDR010000096         3017 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.096, whole genome shotgun sequence.
ACCESSION   DAVBDR010000096 DAVBDR010000000
VERSION     DAVBDR010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3017)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3017)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3017
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.096"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            complement(384..1859)
                     /locus_tag="VQ540_002036"
     CDS             complement(384..1859)
                     /locus_tag="VQ540_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000661022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HET2545780.1"
                     /translation="MKELDQNQAPIYEALVKLRKKRIVPFDVPGHKRGRGNPELVELL
                     GEKCVGIDVNSMKPLDNLGHPISIIRDAEELAADAFGASHAFLMIGGTTSSVQTMILA
                     TCKAGDKIILPRNVHKSAINALVLCGAIPIYIEMSVDPKIGIALGLENDRVAQAIKDH
                     PDAKAILINNPTYYGICSDLKGLTEMAHEAGMMVLVDEAHGAHLHFTGKLPISAMDAG
                     ADMAAVSMHKSGGSLTQSSLLLIGEQMNPEYVRQIINLTQSTSASYLLMASLDISRRN
                     LALRGKESFEEVIELSEYARHEINAIGGYYAYSKELIDGVSVCDFDVTKLSVYTQGIG
                     LTGIEVYDLLRDEYDIQIEFGDIGNILAYISIGDRIQDIERLVGALADIKRLYSRDGK
                     DLIAGEYIQPELVLSPQEAFYSERKSLTLDDSVGQVCGEFVMCYPPGIPILAPGERIT
                     REIVDYIQFAKERGCSLQGTEDPEVNHINVIKRKTNYKKSQ"
     gene            2566..2961
                     /locus_tag="VQ540_002037"
                     /pseudo
     CDS             2566..2961
                     /locus_tag="VQ540_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153868.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
BASE COUNT          951 a          644 c          555 g          867 t
ORIGIN      
        1 ataagaaaga cgctcatggc atcgctctta aacttctttc tgaccccaat cgtgaacaat
       61 ttcaacacga taatcggcaa gtagaactaa aaatactgac tagacatatt catcgtctca
      121 agaaaaaaca gtctgattgg aaagtacaat acactcgttg tcttgatatc atctttcctg
      181 agttggataa aatcgttgga aagcattcag aatataccta ccaactcttg acacgctacc
      241 ctaatcctca gaaaaggatt gaggcaggat ttgataagct gatagaaatt aagcgattga
      301 ccgcttctaa ttcaagggct ttttgccgtg ctctaaaatc atcgccaaat catcaaattg
      361 aaataagaaa tagtttagat aaactattga cttttcttat agtttgtctt tctcttaata
      421 acgttgatat gattgacctc tggatcttcc gtcccttgga gggagcaacc acgttccttg
      481 gcgaattgga tatagtcgac aatttctcgt gtaatgcgtt caccaggagc caagatagga
      541 atacctggag ggtaacacat aacaaattct ccacagacct gtccaacaga atcatccaaa
      601 gttaaacttt ttctttctga atagaaggct tcttgcggag acagcactaa ctcgggctga
      661 atatattctc ctgctatcaa atcttttcca tctcttgaat agagtctctt aatatcagcc
      721 agagcaccaa ccaagcgctc gatgtcttgg atgcggtcgc cgatggaaat ataggccaag
      781 atattgccga tatcaccaaa ctcgatctga atgtcgtatt cgtctcgcaa gaggtcataa
      841 acctcgatac ctgttaagcc aataccctga gtgtaaactg acaacttagt tacgtcaaaa
      901 tcgcaaaccg aaacaccgtc tattaactct tttgagtagg catagtagcc accgatagca
      961 ttgatttcat gacgagcgta ctcggatagc tcaatgactt cctcaaacga ctctttacca
     1021 cgaagggcca agttgcgacg tgaaatatcc aaactagcca tcaataagta agaggcagat
     1081 gtagactggg tcaggtttat aatctgacga acgtactcgg gattcatctg ctccccgatt
     1141 aaaagaagcg aactttgtgt caaactccca ccagacttat gcatggaaac tgctgccata
     1201 tcagctcctg catccatagc agaaattgga agtttaccag tgaaatgcaa atgcgctcca
     1261 tgggcttcat ctactaaaac catcatgcca gcttcatgag ccatttctgt caaccccttt
     1321 aggtctgaac agatgccgta gtaagtagga ttgttgatta ggatagcctt agcatctgga
     1381 tggtccttta tggcctgtgc tactcggtca ttttcaagac ctaaagcgat accaatctta
     1441 ggatctacac tcatctcgat atagatggga atggcaccac atagaaccaa cgcattgata
     1501 gcagatttat ggacatttcg tggcagaata atcttatctc ctgccttgca ggttgccaga
     1561 atcatagtct gcaccgatga agttgttcca ccaatcatta gaaaggcatg gctagctcca
     1621 aaagcatctg cagccagctc ctctgcatca cgaataatcg aaataggatg gcctaaatta
     1681 tccaagggtt tcatcgaatt gacatcaatg cctacacatt tttctcctaa gagttcgaca
     1741 agttctggat ttccccgtcc acgcttgtga cctggaacat caaagggaac aatccttttc
     1801 ttgcgtaact tcaccaaggc ctcataaatt ggggcttggt tttgatctaa ctctttcaaa
     1861 acatactcct ttcaatattt ttaggacctt atgaaaacta aggaactaaa ggttgactca
     1921 tgaaaaaaga gcaggttttc acctgctctg caatcttctg acgtgtttat tttggtttct
     1981 gttgagtatg tctgttcccg atgtttccta actctctagt agcaaatatt acgtacttta
     2041 ttgatcgttt cacaagatga cgtgtgcttt caccacacta aaaatttatg aattaggaca
     2101 agtgtcctaa catcaactta taaaagtagg cttttaaccc tatcaataat gtggcttttc
     2161 aaccacgctt cggcattcaa ccctgcctgt ccgtaggcat tttttactcg ggtttatatt
     2221 tgctagaaaa catcatctca ttttctaagc tttattacta tatcatgttt ttaagaactt
     2281 gtaaagtatt ttttgataaa aaacaaaaat ataatagatt gaaactagaa tagtacacct
     2341 ctgcttctaa aacattgtta gaaatagatt ttactgtcct gatcgatttg ttctgttctt
     2401 gtttcatttt actatatgtt cgtaaatgaa agttctataa tgaagttagc cacccagccc
     2461 tcctaaaaat tagatggttc aactagctga tagctcttgt aggcataaga aaacacctct
     2521 gtgttatact tgttgttcaa ccacaaacac aagaaaggca cagaaatgca agacaattat
     2581 actacaaaag gtaaacattt gacaatcgat agccgtcgct taatcgaaag atggaaaaaa
     2641 gaaggaaaat caaatagaga aattgcctct ctacttggaa aagctcctca aactatccac
     2701 actaaaatca agcgtaggac agtccgaaaa tgtcttggaa aagggcgctt caaagaggtt
     2761 tattctgccg actatgctca acagtcttat gaaaataatc gcaagcactc ggtcaagaga
     2821 tcaagcgtga ccaaggaact aaaggaaaag attctccact atcataacca aaaatttttg
     2881 cctgaaatga tggttatggc taaaggggtt aacgtgggaa tttcaaccat ttactattgg
     2941 attcatcatg gaaaattggg gtaaagcaag caggatctgc tttaccctag aaaaggaaaa
     3001 gtgcttaaga aacaggc
//
LOCUS       DAVBDR010000097         2928 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.097, whole genome shotgun sequence.
ACCESSION   DAVBDR010000097 DAVBDR010000000
VERSION     DAVBDR010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2928)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2928)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2928
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.097"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            complement(481..1206)
                     /locus_tag="VQ540_002038"
     CDS             complement(481..1206)
                     /locus_tag="VQ540_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2545781.1"
                     /translation="MKLLKNELIKSKIFLFIIVDICIQILVILAIKTYILDISAPYSE
                     LDYNKYWYVLHALIYMPMIFPIQILYQNLREALIEDNNNGWNIMVINTNNLVKIIYIK
                     VTINIVRCFICYFVYTIFSLIQLGGMGTDMLLTNIIFPNIIFPNIMSFLLFLPIAIFM
                     QICCIRFDSILAKALPNILLILIVLITFQSDWNIFIPATYYYTEIQSTTNLGIKLLVC
                     IWIMGFEFSLLPKLIKLKEQNLV"
     gene            complement(1219..1956)
                     /locus_tag="VQ540_002039"
     CDS             complement(1219..1956)
                     /locus_tag="VQ540_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2545782.1"
                     /translation="MIKLEFLKQKKSILWFVLIFPIILNALLYIDLTFRYRGYLLVHQ
                     NELALSNWQLIFKEQTIFYFSELFYLVLSLIIYEVFAVEFKNDAWLTVISLPFRNKYT
                     INSKLLITVVYTFTFWLSDYISLYVIGKAIDNSLEIGLIFFLKTFTIQLISSLMIMLL
                     YFLTLVLIRKISGIIPIGIIMMILTISIYYNDYNFKIYLPFTYLSHAFRVTESQFYMI
                     LLSNIIIIVLFYILIRKLNERSFEMKL"
     gene            complement(1949..2677)
                     /locus_tag="VQ540_002040"
     CDS             complement(1949..2677)
                     /locus_tag="VQ540_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET2545783.1"
                     /translation="MAIVEIINLTKSFKDIEVIHNTSFYLNKGKVYGFVGPNGAGKTT
                     IIKMILGILKPDSGKITIFNQTVEQNSKNILSRIGLVLGPSFYGHLDAYKNLKLIANM
                     KGLSLDTERLNEYLSMVGLKDVKKKKVKNFSMGMKQRLSIAASLLGSPEILIWDEPIN
                     GLDPQGVIEIRSLIRFLQEKKGITFLISSHILSELDKVISDIIIINYGKVEFFGSCHY
                     LLQKYNCRNLEEAYLACLAGGEYD"
     gene            complement(2711..2881)
                     /locus_tag="VQ540_002041"
     CDS             complement(2711..2881)
                     /locus_tag="VQ540_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2545784.1"
                     /translation="MKKVNEYVISTAASLGVMIGIVFAIFLDFPVEYGISLGLLNGIV
                     LGSLIVYKNNKN"
BASE COUNT         1103 a          450 c          347 g         1028 t
ORIGIN      
        1 tggacatttt gaactaaaat taatttatta aacatatctc ataagcatat ctattatagg
       61 tgagacaata ttaagaaaga cggttaaaaa acaacctgac tccactggaa ttcaggaatc
      121 aggtcgctta agattttata ttattttact gtctacttga cagggagctg ttcaccaatg
      181 ggaatctata gctttttttg tgactgagaa ctattttatc tcagacttct tcaacacacc
      241 ttattattgg gcacttacgg aaggttaatg aattatttaa aataaaagta aagagaagca
      301 aacagacact ctatagctgt tagacgcttt ttagagtaat aacaatttga taaagtgaat
      361 acaacttgct taattaagcg taagaaacca gaatcataaa atcaattact ttgaagtcat
      421 gactcacgtt gtattgtttc attgttaatc gtattcaatt atttaatttt cgagcaacat
      481 ttaaactaga ttttgttctt tcaattttat tagttttgga agaagggaaa attcaaatcc
      541 cataatccag atacaaacta ataatttaat acctaagttt gtagttgact gaatttctgt
      601 ataataataa gttgcaggta taaatatatt ccaatcactc tgaaacgtga ttaaaacaat
      661 aagtatcagc aaaatattag gtaaggcctt tgctaaaatg gaatcaaatc ttatacagca
      721 aatttgcata aagatagcta taggtaaaaa taacagaaat gacattatat tgggaaatat
      781 tatattggga aatattatat tggttaataa catatcagtt cccataccac ctaattgaat
      841 taaagaaaaa attgtataaa caaaataaca aataaaacat ctcacgatat ttatcgttac
      901 ttttatatag atgattttca cgagattatt agtgttaatc accatgatat tccaaccatt
      961 attattatct tcaatcaatg cctctcttag attttgatac aaaatttgta taggaaaaat
     1021 cattggcata tatattaaag cgtgtaaaac ataccaatac ttattataat caagctctga
     1081 gtatggtgcc gaaatatcta aaatatatgt ttttatagct agaatgacta gaatctgaat
     1141 acagatgtca acaataataa ataaaaatat tttactctta atcaattcat ttttaagtaa
     1201 cttcattttt attacctatt aaagtttcat ctcaaaactt ctttcgttca atttacgaat
     1261 taatatataa aaaagtacga tgattattat attagatagt aaaatcatat aaaattgact
     1321 ttcagtcact ctaaaagcat gagaaagata agtaaatggt aagtaaatct taaaattata
     1381 atcgttgtag tatatgctaa ttgttaaaat catcattata ataccaattg gtattattcc
     1441 agaaattttc cttataagta ctaaagttag aaaatataat aacattatca tcaacgagga
     1501 aattaattga atggtaaatg tttttaaaaa gaaaatcaaa ccaatctcta aactgttatc
     1561 aatagccttc ccaataacgt ataagctaat ataatcagac aaccaaaaag taaatgtgta
     1621 aaccactgta atgagtaatt tagaatttat tgtgtacttg tttctaaatg gcaatgaaat
     1681 tacggttaac catgcatcat ttttaaattc tactgcaaac acttcgtaaa ttattaaaga
     1741 tagaactaaa taaaatagtt cagaaaaata aaatattgtt tgttctttaa aaattaactg
     1801 ccaattagat aaagcaagtt cattttgatg caccaataaa taacctcgat acctaaaagt
     1861 taagtctata tataacaaag cattcagaat tattggaaaa ataagaacaa accataagat
     1921 gctttttttc tgctttagaa actctaattt aatcatattc acctccagct aaacaagcta
     1981 agtaggcttc ttccagattt cgacaattat acttttgtaa aaggtagtgg caagaaccaa
     2041 aaaattcaac tttcccataa tttataatta taatatcaga tatcacttta tccagttcac
     2101 taagaatatg acttgatatt aaaaatgtaa tacctttttt ctcctgtaga aaacggatta
     2161 aacttctaat ttcaattaca ccctgtggat caagtccatt gattggttca tcccaaatta
     2221 atatttctgg actacctaac aatgatgcag ctatacttag acgttgtttc atgcccattg
     2281 aaaaattttt cacttttttc tttttaacat cttttaatcc taccattgat agatattcat
     2341 taagtctttc agtatctaaa ctaagccctt tcatatttgc tattaacttc aaatttttat
     2401 aagcatcaag atgaccataa aatgaaggtc ccaaaactaa tcctatccta gataatatat
     2461 ttttggaatt ctgttctacg gtttgattaa aaatagttat tttcccagaa tctggtttta
     2521 aaatccctag aatcattttg ataattgtag tttttccagc cccatttggt ccaacaaaac
     2581 catatacttt tcccttattt aaataaaatg aagtgttatg aataacttca atatctttaa
     2641 agctttttgt tagatttata atttcaacta tagccatctc tactccttag tttacagcaa
     2701 aaaattatgc ttaattctta ttgtttttgt aaacaatcag cgaacccaat actattccat
     2761 tcaacaaacc taaagaaata ccatattcaa ctggaaaatc taaaaaaatt gcaaatacta
     2821 ttccaatcat cacccctagt gaggctgctg ttgaaattac atattcattt actttcttca
     2881 ttttctttac acctcatttc ctttttgtat ataagctgta gtactatc
//
LOCUS       DAVBDR010000098         2747 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.098, whole genome shotgun sequence.
ACCESSION   DAVBDR010000098 DAVBDR010000000
VERSION     DAVBDR010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2747)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2747)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2747
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.098"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            368..1714
                     /gene="gdhA"
                     /locus_tag="VQ540_002042"
     CDS             368..1714
                     /gene="gdhA"
                     /locus_tag="VQ540_002042"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HET2545785.1"
                     /translation="MTSAKEYIQSVFETVKARNGHEAEFLQAVEEFFNTLEPVFEKHP
                     EYIEENILARITEPERVVSFRVPWVDRDGKIQVNRGYRVQFNSAVGPYKGGLRFHPTV
                     NQGILKFLGFEQIFKNVLTGLPIGGGKGGSDFDPKGKTDAEVMRFCQSFMTELQKHIG
                     PSLDVPAGDIGVGGREIGYLYGQYKRLNQFDAGVLTGKPLGFGGSLIRPEATGYGLVY
                     YTEEMLKANGNSFAGKKVVISGSGNVAQYALQKATELGATVISVSDSNGYVIDENGID
                     FDLLVDVKEKRRARLTEYAAEKATATYHEGTVWTYAGNYDIALPCATQNEINGEAAKR
                     LVAQGVICVSEGANMPSDLDAIKVYKENGIFYGPAKAANAGGVAVSALEMSQNSLRLS
                     WTREEVDGRLKDIMTNIFNTAKTTSETYGLDKDYLAGANIAAFENVANAMIAQGIV"
     gene            complement(2220..2390)
                     /locus_tag="VQ540_002043"
     CDS             complement(2220..2390)
                     /locus_tag="VQ540_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2545786.1"
                     /translation="MKKENEYVILTIASLGVMIGIVFAIFLDFPVEYGISLGLLNGIV
                     LGSLIVYKNNKN"
     gene            complement(2403..>2747)
                     /locus_tag="VQ540_002044"
     CDS             complement(2403..>2747)
                     /locus_tag="VQ540_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001082046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET2545787.1"
                     /translation="AMPMKFNTIISEMGSNISGGQRQQIALARALINNPSIVILDEAT
                     SALDTINEERITKYIQSQGCTQIIIAHRLSTIKDADIIFVMKGGKIVESGNHKYLITL
                     GGEYYSLYTKRK"
BASE COUNT          871 a          513 c          468 g          895 t
ORIGIN      
        1 ttggatttct tctttagttg atttcatatc actattatat aatgattttt gattttagtc
       61 tggtataaat attgctttcc tccaaaatgg tcataatttt actagcaaat ctaacatatc
      121 acggataaat taacaagtga tttctgaatt gctaaacatt ttcttttctt atagcatacc
      181 atactttaag attttgtctt tgagaaagat atttccaaga aaaacgttcg tttttttatc
      241 tattttcaaa aaaaccaaaa actgaattga aagaattttt agaaaatttc tgttttttct
      301 ttacagtgaa aaaaaattct gctataatgt cttatgtaat aaaatatgac aataaaagga
      361 gaacgatatg acatctgcta aagaatatat ccaaagcgtg tttgaaactg tgaaagctcg
      421 taacgggcac gaggctgaat tcctccaagc tgttgaagaa tttttcaaca ctttagaacc
      481 tgtatttgaa aaacaccctg agtatatcga agaaaatatc ttggcacgta ttactgagcc
      541 tgagcgcgtg gtttctttcc gtgttccttg ggttgaccgt gatggaaaaa ttcaagtaaa
      601 ccgtggttac cgtgttcaat tcaactcagc tgttggacca tacaaaggtg gacttcgttt
      661 ccacccaact gtaaaccaag ggatcttgaa attcctcgga tttgaacaaa tctttaaaaa
      721 tgtcttgact ggacttccta tcggtggagg taaaggtgga tcagacttcg atcctaaagg
      781 taaaacagat gctgaagtga tgcgcttctg ccaaagcttc atgactgaat tgcaaaaaca
      841 catcggacca tcacttgacg tacctgctgg tgatatcggt gttggtggac gtgaaattgg
      901 ttacctttac ggtcaataca aacgtcttaa ccaatttgat gctggtgtct tgactggtaa
      961 acctcttgga tttggtggta gcttgattcg tccagaagca actggttacg gtttggttta
     1021 ctatactgaa gaaatgctca aagctaacgg taacagcttt gctggtaaga aagtcgttat
     1081 ttcaggttct ggtaacgttg ctcaatatgc tcttcaaaaa gcaactgaac tcggtgcaac
     1141 tgttatttct gtttctgact caaatggtta tgtcatcgat gaaaatggta tcgacttcga
     1201 tcttttggtt gatgttaaag aaaaacgtcg tgctcgtttg actgagtatg cagctgaaaa
     1261 agcaactgca acctaccacg aaggtactgt atggacttac gctggaaact atgacattgc
     1321 tcttccatgt gccactcaaa acgaaatcaa cggtgaagca gctaaacgtt tggttgctca
     1381 aggcgttatc tgtgtatctg aaggtgccaa catgccgagc gaccttgatg ccatcaaagt
     1441 ttacaaagaa aatggtatct tctacggacc tgcaaaagct gccaacgctg gtggtgtagc
     1501 cgtttcagct cttgaaatga gccaaaacag tcttcgcctc tcatggactc gtgaagaagt
     1561 tgatggccgt ctcaaagaca tcatgacaaa catcttcaac acagctaaaa cgacttcaga
     1621 aacatacggt cttgataaag actaccttgc aggagctaac attgctgcct ttgaaaatgt
     1681 agcaaatgcc atgattgcac aaggtattgt ttaagattta tttactcaat cctcaatcac
     1741 tacgattggg gatttttagc ttgaattaaa aaattggaaa atctaattaa ataaaatgaa
     1801 atgaaataaa aactgaacaa attgattgcg gaattcaaac caatttctaa catacttcta
     1861 gaaattaatt tgacttttct aatcgatttg ttcatatctt atttcaattt actatactta
     1921 cttaaccctt tttatactca atgaaaatca aagagcaaac taggaagcga gccgcaggct
     1981 gtacttgagt acggcaaggc aaagctgacg tggtttgaag agattttcaa agagtattaa
     2041 acaaaaagaa aaaccgctac tcctaagaat agcgatttaa tcatgttttt aagctactac
     2101 tgtagttgct ctattattta agtgttatga ataacttcaa tatctttaaa gctttttgtt
     2161 agatttataa tttcaactat agccatctct actccttagt ttacagcaaa aaattatgct
     2221 taattcttat tgtttttgta aacaatcagc gaacccaata ctattccatt caacaagcct
     2281 aaagaaatac catattcaac tggaaaatct aaaaaaattg caaacactat tccaatcatc
     2341 acccctagtg aggctattgt taaaattaca tattcatttt ctttcttcat tttctttaca
     2401 cctcatttcc tttttgtata taagctgtag tactctccac caagagttat taagtactta
     2461 tgatttcctg actcaacaat cttaccacct ttcattacaa aaataatatc cgcatcctta
     2521 atcgttgaca atctatgagc tataattatt tgagtacaac cctgactttg tatatacttt
     2581 gttattcttt cctcattaat agtgtctaat gcactagttg cttcatctaa aattacaata
     2641 ctaggattat ttattaatgc acgtgccagt gctatctgtt gcctttgccc acctgaaata
     2701 tttgacccca tctctgagat gatagtatta aatttcatcg gcatagc
//
LOCUS       DAVBDR010000099         2653 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.099, whole genome shotgun sequence.
ACCESSION   DAVBDR010000099 DAVBDR010000000
VERSION     DAVBDR010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2653)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2653)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2653
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.099"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            441..2546
                     /locus_tag="VQ540_002045"
     CDS             441..2546
                     /locus_tag="VQ540_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001063457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HET2545788.1"
                     /translation="MNNNFNNFNNMDDLFNQLMGGMRGYSSENRRYLINGREVTPEEF
                     AHYRATGQLPGNAETDVQMPQQASGMKQDGVLAKLGRNLTAEAREGKLDPVIGRNKEI
                     QETSEILSRRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGL
                     EAGTQYRGSFEENVQNLVNEVKEAGNIILFFDEIHQILGAGSTGGDSGSKGLADILKP
                     ALSRGELTVIGATTQDEYRNTILKNAALARRFNEVKVNAPSAENTFKILQGIRDLYQQ
                     HHNVILPDEVLKAAVDYSVQYIPQRSLPDKAIDLVDVTAAHLAAQHPVTDVHAVEREI
                     ETEKDKQEKAVEAEDFEAALNYKTRIAELERKIENHTEDMKVTASVNDVAESVERMTG
                     IPVSQMGASDIERLKDMAHRLQEKVIGQDKAVEVVARAIRRNRAGFDEGNRPIGSFLF
                     VGSTGVGKTELAKQLALDMFGTQDAIIRLDMSEYSDRTAVSKLIGTTAGYVGYDDNSN
                     TLTERVRRNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNTVVIATS
                     NAGFGYEANLTEDADKPELMDRLKPFFRPEFLNRFNAVIEFSHLTKEDLSKIVDLMLA
                     EVNQTLAKKDIDLVVSQAAKDYITEEGYDEVMGVRPLRRVVEQEIRDKVTDFHLDHLD
                     AKHLEADMEDGVLVIREKA"
BASE COUNT          848 a          482 c          607 g          716 t
ORIGIN      
        1 cgatttatcc tgttcttatt tcattttact atacagtttt gagatggttg atagaactga
       61 cgaagtcagc tcaaaacact gttttgaggt tgtagacaag gcgaagctga tgtggtttga
      121 agaggttttc gaagagtgta aaaaaatatt ggtcagttaa agtcaaaact cttgaccttt
      181 tctgaccaat gtagtatatt atgaacgtaa ggtaaatgaa agccttacta gaacacttat
      241 ttaaagtaaa atagaaagag gtgagtctat gtttcatcta gcaatcttca gaggtaaaga
      301 tagtctactc ctgcttgaaa aagaaaaacc agaaatagta cgtagggtag cgatctagct
      361 agtctaaatt ttttaaaaca atggtcaaag atagtcaata tcagtaatca taactaagta
      421 aacaaaaaga ggtaaagaat atgaataaca actttaataa ttttaataac atggatgatt
      481 tatttaacca attgatgggt ggtatgcgag gatatagttc tgaaaatcgc cgttacttaa
      541 ttaatggacg cgaagtcaca cctgaggaat ttgctcacta tcgtgcgact ggtcaattac
      601 caggaaatgc agaaactgat gtgcaaatgc cacaacaggc atcaggtatg aaacaagacg
      661 gtgtccttgc aaaactaggt cgaaacttaa cagcagaagc gcgtgagggc aagttggatc
      721 ctgttatcgg acgaaacaag gaaattcaag aaacatctga aatcctctca cgccgcacca
      781 agaacaatcc tgttttggtc ggagatgcag gtgttggtaa gacagcagtt gtcgaaggtc
      841 tagcgcaagc cattgtgaac ggagatgttc ctgctgctat caagaacaag gaaattattt
      901 ccattgatat ctcaggtctt gaggctggta ctcaataccg tggtagcttt gaagaaaatg
      961 tccaaaactt agtcaatgaa gtgaaagaag cagggaatat tatcctcttc tttgatgaaa
     1021 ttcaccaaat tcttggtgct ggtagcactg gtggagacag tggttctaaa ggacttgcgg
     1081 atattctcaa gccagctctc tctcgtggag aattgacagt gattggggca acaactcaag
     1141 acgaataccg taacaccatc ttgaagaatg ctgctcttgc tcgtcgtttc aacgaagtga
     1201 aggtcaatgc tccttcagca gagaatactt ttaaaattct tcaaggcatt cgtgacctct
     1261 atcaacaaca ccacaatgtc atcttgccag acgaagtctt gaaagcagcg gtggattatt
     1321 ctgttcaata cattcctcaa cgtagcttgc cagataaggc tattgacctt gtcgatgtaa
     1381 cggctgctca cttggcggct caacatccag taacagatgt gcatgctgtt gaacgagaaa
     1441 tcgaaacgga aaaagacaag caagaaaaag cagttgaagc agaagatttt gaagcagctc
     1501 taaactataa aacacgcatt gcagaattgg aaaggaaaat cgaaaaccac acagaagata
     1561 tgaaagtgac tgcaagtgtc aacgatgtgg ctgaatctgt ggaacgaatg acaggtatcc
     1621 cagtatcgca aatgggagct tcagatatcg aacgtttgaa agatatggct catcgcttgc
     1681 aagaaaaggt gattggtcaa gataaggccg tagaagttgt agctcgtgct atccgtcgta
     1741 accgtgctgg ttttgatgaa ggaaatcgcc caatcggcag cttcctcttt gtagggtcta
     1801 ctggggttgg taagacggag cttgctaagc aattggcact cgatatgttt ggaacccagg
     1861 atgcgattat ccgtttggat atgtctgaat acagtgaccg cacagctgtt tctaagctaa
     1921 ttggtacaac agcaggctat gtgggttatg atgacaatag caatacctta acagaacgtg
     1981 ttcgtcgcaa tccatactct atcattctct tggatgaaat tgaaaaggct gatcctcaag
     2041 ttattaccct tctcctccaa gttctagatg atggtcgttt gacagatggt caaggaaata
     2101 cagtaaactt caagaatact gtcgttattg cgacctcaaa tgctggattt ggctatgaag
     2161 ccaacttgac agaagatgcg gataaaccag aattgatgga ccgtttgaaa cccttcttcc
     2221 gtccagaatt cctcaaccgc tttaatgcag tcatcgagtt ctcacacttg actaaggaag
     2281 acctttctaa gattgtagat ttgatgttgg ctgaagttaa ccaaaccttg gctaagaaag
     2341 acattgactt ggtagttagt caagcggcta aagattatat cacagaagaa ggttacgacg
     2401 aagtcatggg ggttcgtcct ctccgtcgcg tggttgaaca agaaattcgt gataaggtga
     2461 cagacttcca cttggatcat ttagatgcta aacatctgga agcagatatg gaagatggcg
     2521 ttttggttat tcgtgagaaa gcctaagata gaattttgag gataaaaaag aaggagccag
     2581 ctgaaaaaaa ctggttcctt tttaggtacg acaggcatgt cgtatagtag aagtgtatta
     2641 ttccagtttc aat
//
LOCUS       DAVBDR010000100         2621 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.100, whole genome shotgun sequence.
ACCESSION   DAVBDR010000100 DAVBDR010000000
VERSION     DAVBDR010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2621)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2621)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2621
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.100"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            203..517
                     /locus_tag="VQ540_002046"
     CDS             203..517
                     /locus_tag="VQ540_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2545789.1"
                     /translation="MWVLGFILFLIFFYSNDSKKIKKLEKKIKRLERKEKGNAEMSRL
                     LQEMIGKEPIITGVYIGPDNWEVVDVDEEWVKLRRVDNTGKEKFKLQRIEDIQTVEFD
                     GE"
     gene            527..733
                     /locus_tag="VQ540_002047"
     CDS             527..733
                     /locus_tag="VQ540_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001176227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET2545790.1"
                     /translation="MQLKNRLKELRARDGLNQTDLAKLAGVSRQTISLLERDEYTPSI
                     IIALKISQIFNETVESVFRLEEDE"
     gene            733..930
                     /locus_tag="VQ540_002048"
     CDS             733..930
                     /locus_tag="VQ540_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001046145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2545791.1"
                     /translation="MNKYKVIYYVVVIALLVSVFLLIGMDLSWFNPYQSDQFVWVYFA
                     LIPVIEWIEKKSKNLASEKGE"
     gene            986..1666
                     /locus_tag="VQ540_002049"
     CDS             986..1666
                     /locus_tag="VQ540_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001833114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3169 family protein"
                     /protein_id="HET2545792.1"
                     /translation="MGMFVGMFKARVESHEIILDVKALMPWISAICLLIGFISMFLTF
                     NFLKKSRKFHSLYQEEMDDDLNETYYVQMYRNLEFGTIAFNITGVVIPLAIFISLSEV
                     IILHTNPQTFFLSFLLFVVFLVAQKSLFKTIAIVRQFDLEFFATPKDVLNYINSYDEG
                     ERQANLEQSFRILFQLHQYVLPALYIFLIILSFLTGEIQLLAFLLVGAIHVYINVMQL
                     PMVKRYFK"
     gene            1678..2319
                     /locus_tag="VQ540_002050"
     CDS             1678..2319
                     /locus_tag="VQ540_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET2545793.1"
                     /translation="MKLLKNLGWFLLALLSFFFIYGFIQGLATASLALGASPYAVTLL
                     YVVLAGVYVYGIYKWYQKAPVYIEKSGFNRFIWLPALVWFLSLVVQFFLPDDPSVNQQ
                     IATDLTLSQPLFSFFAVVIFAPLTEEIVFRGMLARYLFPKQDNSKRTLIFLLVSSLLF
                     ALIHFPGDVQQFFVYFSLGFSLGLAYISRKGLVYSISLHALNNLVGFLMILML"
     gene            2337..2567
                     /locus_tag="VQ540_002051"
     CDS             2337..2567
                     /locus_tag="VQ540_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000832182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2545794.1"
                     /translation="MKRVILLAVIQAVVLFFIIGALAYAFKGDFFYNYLAVVFAPIAG
                     VLRFGTAYITEIVLPRKAAEIAEKRKAGKNSK"
BASE COUNT          764 a          431 c          541 g          885 t
ORIGIN      
        1 cctacggcaa ggtgaagctg acgtggtttg aagagatttt agaagagtat taatgataga
       61 taaagtggtc aggaacctac tcctgacctt tttcttttgc aaaatgacaa aaatcataat
      121 ttttttgaca actatacttg tcaaaaagaa aaagatgtgt tacaatgtaa gcaagttaag
      181 agaaaagaag aaaggagcta tgatgtgggt actagggttt atactatttc tgattttctt
      241 ttattctaat gattctaaaa aaatcaagaa actagagaag aaaatcaaaa gacttgagcg
      301 aaaagagaaa ggaaatgcag aaatgtcgag attattacaa gaaatgattg gaaaggaacc
      361 aattataacg ggagtgtata ttgggccaga taactgggaa gttgtggatg ttgatgagga
      421 atgggtaaag ctacgacgtg tagataatac gggaaaagaa aaattcaagt tgcaacgtat
      481 tgaggatatc caaaccgttg aatttgacgg agagtaggtg tgtaacatgc aactaaaaaa
      541 tcgtctaaaa gagcttcgag ctcgcgatgg tctcaatcaa accgacctag ccaaactggc
      601 aggggtttcc agacagacca ttagcctact agaacgggat gagtacaccc catccattat
      661 cattgccctg aaaatatctc aaattttcaa cgaaacagtc gaatcggtat ttcgtttgga
      721 ggaggacgag tgatgaacaa gtataaagtg atttattatg tagtggtcat agctttatta
      781 gtcagcgtat ttctactgat tgggatggac ctaagctggt ttaatcccta tcaaagcgac
      841 caatttgttt gggtctactt tgctctcatc ccagtaattg aatggattga aaagaaatcc
      901 aaaaatctag caagtgaaaa aggagaatga atatgaaaaa gaaacgtaga ttgttatttt
      961 tgatgtctat tgtcttgggg ggttcttggg catgtttgta gggatgttta aggcacgtgt
     1021 cgaatcccac gaaattattt tagatgtaaa agccttgatg ccatggatat cagctatttg
     1081 tttactgata ggtttcatta gtatgttttt gactttcaat ttcttaaaga aaagcagaaa
     1141 atttcattcc ttgtatcaag aggaaatgga tgacgatctg aatgaaacct attatgtgca
     1201 aatgtatcgg aatcttgagt ttggaaccat tgcttttaat attacaggtg tagtgattcc
     1261 attggctatt tttatttcat taagtgaggt gattatattg catacaaacc ctcaaacatt
     1321 tttcctttct ttcttactct ttgtggtatt cttagtcgct caaaaatctc tttttaaaac
     1381 cattgcgatt gttcgtcagt ttgatttgga atttttcgct acaccaaagg atgtcttgaa
     1441 ctatataaat tcttatgatg aaggggagcg tcaggctaat ttggaacaga gttttcgaat
     1501 tttattccaa ttacaccaat atgtcttacc agccttatat atttttctta ttatcctttc
     1561 tttcttgaca ggagagattc agttactagc tttcttgctt gtaggagcca tccatgttta
     1621 tatcaatgtg atgcagttac ctatggtaaa acgttatttc aaataaagga gttatctatg
     1681 aaattactta aaaaccttgg ctggtttctt ctagcccttc tatccttttt ctttatctat
     1741 ggctttattc aggggctcgc gactgcgtcg cttgctttag gcgcttcacc ctatgctgtt
     1801 actctactct atgtggtctt ggctggagta tatgtgtacg gcatttacaa atggtatcag
     1861 aaagctcctg tttatattga gaagagcggc tttaaccgat ttatttggct tcctgccttg
     1921 gtttggttct tatctctggt cgttcaattc ttcttgccag atgatccttc agtaaatcag
     1981 caaatagcga cagacttgac cttgtctcaa ccacttttct cattctttgc tgtggttatt
     2041 tttgctcctt tgacggaaga gattgttttt agagggatgt tagcacgcta tctctttcct
     2101 aagcaggaca atagtaaacg aaccctgatt tttcttctgg tatctagtct tctatttgcc
     2161 ttgattcatt ttccaggtga tgtgcaacaa ttttttgtct attttagcct tggttttagt
     2221 ttgggtttgg cttacattag cagaaaaggt ctggtctaca gtatttctct tcacgctttg
     2281 aataatttag tcggcttttt gatgattctc atgctataat agagtcagga ggtcacatga
     2341 aacgagtaat tttattagca gtgattcagg cagtcgttct atttttcatc attggagcgc
     2401 tagcttatgc cttcaaaggc gatttcttct ataactatct agcagttgtc tttgctccta
     2461 ttgcaggtgt actgcgtttt gggacggctt acataacgga aattgtcttg cctcgaaagg
     2521 cagccgaaat cgctgaaaag cgtaaagcag gcaaaaattc aaaataaaag agtccggtga
     2581 agttcatcgg atttttgtat tatactcaat gaaaatcaaa g
//
LOCUS       DAVBDR010000101         2607 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.101, whole genome shotgun sequence.
ACCESSION   DAVBDR010000101 DAVBDR010000000
VERSION     DAVBDR010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2607)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2607)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2607
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.101"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            114..1031
                     /locus_tag="VQ540_002052"
                     /pseudo
     CDS             114..1031
                     /locus_tag="VQ540_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001822901.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-dependent transporter"
     gene            complement(1071..2015)
                     /gene="manA"
                     /locus_tag="VQ540_002053"
     CDS             complement(1071..2015)
                     /gene="manA"
                     /locus_tag="VQ540_002053"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HET2545795.1"
                     /translation="MSEPLFLQSVMQEKIWGGTKLRDEFGYDIPSEKVGEYWAISAHL
                     NGVSKVANGRYEGTDLATLYAEHRELFGNRPEPVFPLLTKILDANDWLSVQVHPDDAY
                     GLEHEGELGKTECWYIIAADEGSEIIYGHNAKSKEELRQQIEDKNWDALLTKVPVKAG
                     DFFYVPSGTMHAIGAGILILETQQSSDTTYRVYDFDRKDDKGNLRELHLEKSIDVLNI
                     GEPANSRPVTIKADDLRSTILVSNDFFAVYKWEITGKVNFEKTADYSLLSVLAGQGQL
                     TVDGKNYPIQKGRHFILPSDVESWTLEGQDLELIVSHP"
     gene            complement(2147..2428)
                     /locus_tag="VQ540_002054"
     CDS             complement(2147..2428)
                     /locus_tag="VQ540_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000380698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HET2545796.1"
                     /translation="MDTPDENGYVADDYRITYLEAHIKAMRDAIYKDGVDLLGYTTWG
                     CIDSVSAGTGEMNKRYGFIYVDRDNVGNGTLKRSKKKSFYWYMSFIAMV"
     gene            2493..>2607
                     /locus_tag="VQ540_002055"
     CDS             2493..>2607
                     /locus_tag="VQ540_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
                     /protein_id="HET2545797.1"
                     /translation="MKSTKEEIQTIKTLFKDSRTAKYHKCLQIILFRLMGKS"
BASE COUNT          698 a          606 c          477 g          826 t
ORIGIN      
        1 aaaagtcgtg cgctgaacac caacaagacg cttaaatcgt gcatcagtta gttgtttact
       61 tgcttcatca ttcatagaac tactatgcca tattttgttt cgcaggaagt ctgatcattt
      121 caaatccagc cattgctcta ggagctcaag cgacctttat cctattgaat atcttcattg
      181 tatcacgtgg ggttcaaaaa gggattgaaa gagcttcgaa agtcatgatg cccctgctct
      241 ttatcatctt tgtcgtcatc atcgaacgct ctctcagttt gccaaatgcc atggaagggg
      301 ttctttactt cctcaaacca gatttttcaa aactgactag cgctggtctc ctctatgctc
      361 tgagacaatc tttctttgcc ctctcactag gggttacagc catgttgacc tatgcttctt
      421 acttggacaa gaaaaccaat ctggtccagt caagaatctc catcgtagcc atgaatatct
      481 cggtatccat catggcaggt ctagccattt tccaagctcg gtcccccttc agactgaata
      541 ttgaaggggg accgagcttg gtctttatcg tcttgcctca actctttgac aagatgcctt
      601 ttggaaccat tttctatgtc ctcttcctct ttgcgactgt cacttcttct gtcgttatgc
      661 tggaaatcaa tgtagacaat atcaccaatc aggacaacag caagcgtgct aaatggagtg
      721 ttattttagg aattttgacc tttgtctttg gcattccttc agccctatct tacggtgtca
      781 tggcggatgt tcacattttt ggtaaagcct tctttgacgc tatggacttc ttggtttcca
      841 atctcctcat gccatttgga gctctcttcc tttcactttt tacaggctat atctttaaaa
      901 aggctcttgc aatggaggaa ctccatctcg atgaaagagc atggaaacaa ggactgttcc
      961 aagtctggct cttccttctt cgtttcgtca ttccaatcat catcgtggtc ttcatcgccc
     1021 aatttatgta atcaaaagga cttgagtaat gaactcaggt cctttctttt ttatggatga
     1081 ctaacaatta attctaaatc ttgcccttct agagtccaag attcaacatc acttggtagg
     1141 ataaagtgtc tccctttttg gattggatag tttttcccgt caacagttag ttgaccttga
     1201 ccagccaaga cactcaacaa gctgtagtca gctgtctttt caaagttaac ttttccagta
     1261 atttcccatt tgtaaactgc gaagaaatca ttggatacaa ggatagtgga acgtagatca
     1321 tctgctttga ttgtcactgg acggctattt gcgggttcac caatgttcaa gacatcgata
     1381 gatttttcaa ggtgaagttc acgtaaattg cccttgtcat ccttacggtc aaagtcatag
     1441 acacggtaag tggtatcgct agactgctgg gtttcaagaa tcaagatacc cgccccgata
     1501 gcgtgcatgg taccgcttgg tacatagaag aaatctcctg ctttaactgg cacttttgtc
     1561 aacagcgcat cccagttctt atcctcgatt tgctggcgga gttcttcttt tgacttggca
     1621 ttgtgaccgt agataatctc tgaaccttca tctgctgcaa tgatgtacca acattctgtt
     1681 tttccaagtt cgccttcatg ctcgagtcca taagcatcgt ctgggtgaac ttggacactg
     1741 agccagtcgt tggcatcgag gatcttggtc aaaagtggaa atacaggttc tggacgattg
     1801 ccaaataatt cacggtgttc cgcatacaaa gtagcaagat ctgttccctc gtaacgacca
     1861 ttggcaactt tagaaacacc atttagatga gctgagatag cccagtactc tccgactttt
     1921 tcacttggga tgtcgtagcc aaactcatca cgtagcttgg taccacccca gattttttct
     1981 tgcataactg attgtaaaaa taatggttct gacatcttaa tctcctgtct gatttttctc
     2041 ccctcattat agcaaaaaaa gagttccatt tgaactcttt tttacatctt ataaagcagg
     2101 gagaagattt tataaaaata gtaaacaaat gtgctctact cgatgcttac accattgcta
     2161 taaatgacat gtaccaatag aaggacttct tcttgctacg tttgagagtc ccatttccta
     2221 cattatctcg atctacatag ataaagccat agcgcttatt catttcccct gtgccagctg
     2281 aaaccgaatc gatacagccc catgtcgtat aaccaagcaa gtcaaccccg tctttgtaaa
     2341 tggcatctcg catggccttg atgtgggcct ctaagtaagt aatccgatag tcatctgcta
     2401 cataaccatt ctcatccggt gtatccatag caccgagtcc attttctacg ataatactat
     2461 actaaaatca aaaagcatta tataatagtg atatgaaatc aactaaagaa gaaatccaaa
     2521 ccatcaaaac actttttaaa gactctcgta cagctaaata tcataaatgc cttcaaatca
     2581 ttctatttcg tctgatgggc aaatctt
//
LOCUS       DAVBDR010000102         2376 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.102, whole genome shotgun sequence.
ACCESSION   DAVBDR010000102 DAVBDR010000000
VERSION     DAVBDR010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2376)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2376)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2376
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.102"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            <1..1545
                     /gene="phtA"
                     /locus_tag="VQ540_002056"
     CDS             <1..1545
                     /gene="phtA"
                     /locus_tag="VQ540_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtA"
                     /protein_id="HET2545798.1"
                     /translation="HVESDGLVFDPAQITSRTARGVAVPHGDHYHFIPYSQMSELEER
                     IARIIPLRYRSNHWVPDSRPEQPSPQPTPEPSPGPQPAPNLKIDSNSSLVSQLVRKVG
                     EGYVFEEKGISRYVFAKDLPSETVKNLESKLSKQESVSHTLTAKKENVAPRDQEFYDK
                     AYNLLTEAHKALFENKGRNSDFQALDKLLERLNDESTNKEKLVDDLLAFLAPITHPER
                     LGKPNSQIEYTEDEVRIAQLADKYTTSDGYIFDEHDIISDEGDAYVTPHMGHSHWIGK
                     DSLSDKEKVAAQAYTKEKGILPPSPDADVKANPTGDSAAAIYNRVKGEKRIPLVRLPY
                     MVEHTVEVKNGNLIIPHKDHYHNIKFAWFDDHTYKAPNGYTLEDLFATIKYYVEHPDE
                     RPHSNDGWGNASEHVLGKKDHSEDPNKNFKADEEPVEETPAEPEVPQVETEKVEAQLK
                     EAEVLLAKVTDSSLKANATETLAGLRNNLTLQIMDNNSIMAEAEKLLALLKGSNPSSV
                     SKEKIN"
     gene            1703..>2376
                     /locus_tag="VQ540_002057"
     CDS             1703..>2376
                     /locus_tag="VQ540_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HET2545799.1"
                     /translation="MKINKKYLAGSVATLVLSVCAYELGLHQAQTVKENNRVSYIDGK
                     QATQKTENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIISEE
                     LLMKDPNYQLKDEDIISEIKGGYVIKVDGKYYVYLKDAAHADNVRTKEEINRQKQEHS
                     QHREGGTSTNDGAVAFARSQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKN
                     ELSASE"
BASE COUNT          835 a          430 c          481 g          630 t
ORIGIN      
        1 catgtagaat ctgatggcct tgttttcgac ccagcgcaaa tcacaagtcg aacagctaga
       61 ggtgttgcag tgccacacgg agatcattac cacttcatcc cttactctca aatgtctgaa
      121 ttggaagaac gaatcgctcg tattattccc cttcgttatc gttcaaacca ttgggtacca
      181 gattcaaggc cagaacaacc aagtccacaa ccgactccgg aacctagtcc aggcccgcaa
      241 cctgcaccaa atcttaaaat agactcaaat tcttctttgg ttagtcagct ggtacgaaaa
      301 gttggggaag gatatgtatt cgaagaaaag ggcatctctc gttatgtctt tgcgaaagat
      361 ttaccatctg aaactgttaa aaatcttgaa agtaagttat caaaacaaga gagtgtttca
      421 cacactttaa ctgctaaaaa agaaaatgtt gctcctcgtg accaagaatt ttatgataaa
      481 gcatataatc tgttaactga ggctcataaa gccttgtttg aaaataaggg tcgtaattct
      541 gatttccaag ccttagacaa attattagaa cgcttgaatg atgaatcgac taataaagaa
      601 aaattggtag atgatttatt ggcattccta gcaccaatta cccatccaga gcgacttggc
      661 aagccaaatt ctcaaattga gtatactgaa gacgaagttc gtattgctca attagctgat
      721 aagtatacaa cgtcagatgg ttacattttt gatgaacatg atataatcag tgatgaagga
      781 gatgcatatg taacgcctca tatgggccat agtcactgga ttggaaaaga tagcctttct
      841 gataaggaaa aagttgcagc tcaagcctat actaaagaaa aaggtatcct acctccatct
      901 ccagacgcag atgttaaagc aaatccaact ggagatagtg cagcagctat ttacaatcgt
      961 gtgaaagggg aaaaacgaat tccactcgtt cgacttccat atatggttga gcatacagtt
     1021 gaggttaaaa acggtaattt gattattcct cataaggatc attaccataa tattaaattt
     1081 gcttggtttg atgatcacac atacaaagct ccaaatggct ataccttgga agatttgttt
     1141 gcgacgatta agtactacgt agaacaccct gacgaacgtc cacattctaa tgatggatgg
     1201 ggcaatgcca gtgagcatgt gttaggcaag aaagaccaca gtgaagatcc aaataagaac
     1261 ttcaaagcgg atgaagagcc agtagaggaa acacctgctg agccagaagt ccctcaagta
     1321 gagactgaaa aagtagaagc ccaactcaaa gaagcagaag ttttgcttgc gaaagtaacg
     1381 gattctagtc tgaaagccaa tgcaacagaa actctagctg gtttacgaaa taatttgact
     1441 cttcaaatta tggataacaa tagtatcatg gcagaagcag aaaaattact tgcgttgtta
     1501 aaaggaagta atccttcatc tgtaagtaag gaaaaaataa actaatgaaa aatgaaagtc
     1561 tcgataaaga ggctttcatt tttattatgt atatatgtaa aattcttgac aagcaatatt
     1621 aaaaagagta aactattaac tagttaatta accggtttat tactttatag tgaatcaaat
     1681 atacttaaga aaagaggaaa gaatgaaaat caataaaaaa tatctagctg ggtcagtagc
     1741 tacacttgtt ttaagtgtct gtgcttatga actaggtttg catcaagctc aaactgtaaa
     1801 agaaaataat cgtgtttcct atatagatgg aaaacaagcg acgcaaaaaa cggagaattt
     1861 gactcctgat gaggttagca agcgtgaagg aatcaatgcc gaacaaatcg tcatcaagat
     1921 aacagaccaa ggctatgtca cttcacatgg ggaccactat cattattaca atggtaaggt
     1981 tccttatgac gctatcatca gtgaagaatt gctgatgaag gatccaaact accagctaaa
     2041 ggacgaggat attatcagtg aaatcaaggg tggttatgtg attaaggtag atggaaaata
     2101 ctatgtttac cttaaggatg cagctcatgc ggataatgtc cgtacaaaag aagaaatcaa
     2161 tcggcaaaaa caagaacata gtcagcatcg tgaaggaggg acttcaacaa acgatggtgc
     2221 ggtagccttt gcacgttcac aaggacgcta tactacagat gatggttata tctttaatgc
     2281 ttctgatatc attgaggaca cgggtgatgc ttatatcgtt cctcacggcg accattacca
     2341 ttacattcct aagaatgagt tatcagctag cgagtt
//
LOCUS       DAVBDR010000103         2352 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.103, whole genome shotgun sequence.
ACCESSION   DAVBDR010000103 DAVBDR010000000
VERSION     DAVBDR010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2352)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2352)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2352
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.103"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            complement(26..428)
                     /locus_tag="VQ540_002058"
                     /pseudo
     CDS             complement(26..428)
                     /locus_tag="VQ540_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            complement(373..555)
                     /locus_tag="VQ540_002059"
     CDS             complement(373..555)
                     /locus_tag="VQ540_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HET2545800.1"
                     /translation="MDLKFEGVDLEYKKAKNNLPESFWETYSAFANTNGGKIILGIDE
                     KNIDTYQRVNRLPAKL"
     gene            912..>2352
                     /gene="pcpA"
                     /locus_tag="VQ540_002060"
     CDS             912..>2352
                     /gene="pcpA"
                     /locus_tag="VQ540_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000753868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein PcpA"
                     /protein_id="HET2545801.1"
                     /translation="MKKTTILSLTTAAVILAAYVPNEPILADTPSSEVIKETKVGSII
                     QQNNIKYKVLTVEGNIGTVQVGNGVTPVEFEAGQDGKPFTIPTKITVGDKVFTVTEVA
                     SQAFSYYPDETGRIVYYPSSITIPSSIKKIQKKGFHGSKAKTIIFDKGSQLEKIEDGA
                     FDFSELEEIELPASLEYIGTSAFSFSQKLKKLTFSSSSKLELISHEAFANLSNLEKLT
                     LPKSVKTLGSNLFRLTTSLKHVDVEEGNESFASVDGVLFSKDKTQLIYYPSQKNDESY
                     KTPKETKELASYSFNKNSYLKKLELNEGLEKIGTFAFADAIKLEEISLPNSLETIERL
                     AFYGNLELKELILPDNVKNFGKHVMNGLPKLKSLTIGNNINSLPSFFLSGVLDSLKEI
                     HIKNKSTEFSVKKDTFAIPETVKFYVTSEHIKDVLKSNLSTSNDIIVEKVDNIKQETD
                     VAKPKKNSNQGVVGWVKDKGLWYYLNESGS"
BASE COUNT          822 a          354 c          385 g          791 t
ORIGIN      
        1 tgagccttca tagcgtggca tttcttttta cttccgtcac atcaatcatt accgtgtcct
       61 cagaactgag aggagttctt gaaatcgtaa caccaccttt gaacaagagt tacttcaacc
      121 cattagctcc gacggattaa gttgctttcg tgaataccaa aatcagccgc aatttcttca
      181 taagtgcggt attctcgcac atattgaaga gtggccataa gaaggtcttc taggcttaat
      241 ttaggttttc gtccaccttt tgtgtgttta agttgataag ctgtttttaa cacagctaac
      301 atctcttcaa aagtggtgcg ctgaacacca acaagacgct taaatcgtgc atcggttagt
      361 tgtttacttg cttcataatt tcgcagggag tctattgact ctttggtagg tgtcaatgtt
      421 tttttcatct atcccgagaa ttattttccc gccatttgta tttgcaaatg ctgagtaggt
      481 ttcccagaaa gactctggaa gattgttttt agcttttttg tattctaaat caaccccttc
      541 aaattttaag tccatatttt tcctttacat ctgttttttg tggttctggt atttgttcaa
      601 gttgagtgat aatatagcga attgaatttc gagagttttt actcagttaa tttctttttt
      661 aacccacttt aatttctttt ttaacccact ttaatttctt ttttaacacg ggttaaaaaa
      721 gaaattaaag tgggttaatt tttcttgact taaaatttaa aaatgatata ctgtgtttat
      781 ggagagatga caatttataa aatgtactac tctattctac tagataatga ttgaataaaa
      841 ctttttataa caacggctag caaagttata attttatatc tattagaaaa taaatatgta
      901 aggaaattta aatgaaaaaa actacaatat tatcattaac tacagctgcg gttattttag
      961 cagcatatgt ccctaatgaa ccaatcctag cagatactcc tagttcggaa gtaatcaaag
     1021 agactaaagt tggaagtatt attcaacaaa ataatatcaa atataaggtt ctaactgtag
     1081 aaggtaacat aggaactgtt caagtgggta atggagttac tcctgtagag tttgaagctg
     1141 gtcaagatgg aaaaccattc acgattccta caaaaatcac agtaggtgat aaagtattta
     1201 ccgttactga agtagctagt caagctttta gttattatcc agatgaaaca ggtagaattg
     1261 tctactatcc tagctctatt actatcccat caagcataaa aaaaatacaa aaaaaaggct
     1321 tccatggaag taaagctaaa actattattt ttgacaaagg cagtcagctg gagaaaattg
     1381 aagatggagc ttttgatttt tctgaattag aagagattga attgcctgca tctctagaat
     1441 atattggaac aagtgcattt tcttttagtc aaaaattgaa aaagctaacc ttttcctcaa
     1501 gttcaaaatt agaattaata tcacatgagg cttttgctaa tttatcaaat ttagagaaac
     1561 taacattacc aaaatcggtt aaaacattag gaagtaatct atttagactc actactagct
     1621 taaaacatgt tgatgttgaa gaaggaaatg aatcgtttgc ctcagttgat ggtgttttgt
     1681 tttcaaaaga taaaacccaa ttaatttatt atccaagtca aaaaaatgac gaaagttata
     1741 aaacgcctaa ggagacaaaa gaacttgcat catattcgtt taataaaaat tcttacttga
     1801 aaaaactcga attgaatgaa ggtttagaaa aaatcggtac ttttgcattt gcagatgcga
     1861 ttaaacttga agaaattagc ttaccaaata gtttagaaac tattgaacgt ttagcctttt
     1921 acggtaattt agaattaaaa gaacttatat taccagataa tgttaaaaat tttggtaaac
     1981 acgttatgaa cggtttacca aaattaaaaa gtttaacaat tggtaataat atcaactcat
     2041 tgccgtcctt cttcctaagt ggcgtcttag attcattaaa ggaaattcat attaagaata
     2101 aaagtacaga gttttctgtg aaaaaagata catttgcaat tcctgaaact gttaagttct
     2161 atgtaacatc agaacatata aaagatgttc ttaaatcaaa tttatctact agtaatgata
     2221 tcattgttga aaaagtagat aatataaaac aagaaactga tgtagctaaa cctaaaaaga
     2281 attctaatca gggagtagtt ggttgggtta aagacaaagg tttatggtat tacttaaatg
     2341 aatcaggttc aa
//
LOCUS       DAVBDR010000104         1869 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.104, whole genome shotgun sequence.
ACCESSION   DAVBDR010000104 DAVBDR010000000
VERSION     DAVBDR010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1869)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1869)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1869
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.104"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            <1..250
                     /locus_tag="VQ540_002061"
     CDS             <1..250
                     /locus_tag="VQ540_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HET2545802.1"
                     /translation="SALEEELSNRGYDVHCDAVMVKDVNEDLMKGYDIFTPIAATDLG
                     FEPGIPVIEAGPILFRIPAMSAPVFDNIEAAIKEHGLS"
     gene            298..1773
                     /locus_tag="VQ540_002062"
     CDS             298..1773
                     /locus_tag="VQ540_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HET2545803.1"
                     /translation="MDAIFDLIGKVFNPILEMGGPVIMLIILTVLALLFGVKFSKALE
                     GGIKLAIALTGIGAIIGMLNGAFSASLAKFVENTGIQLSITDVGWAPLATITWGSAWT
                     LYFLLIMLIVNIVMLAMKKTDTLDVDIFDIWHLSITGLLIKWYADNNGVSQGVSLFIA
                     TAAIVLVGVLKIINSDLMKPTFDDLLNAPSSSPMTSTHMNYMMNPVIMVLDKIFEKFF
                     PGLDKYDFDAAKLNKKIGFWGSKFFIGFILGIVIGIMGTPHPIAGVADADKWRLVIKG
                     WLSLGLTAGVSLELFSLIGSWFIAAVEPLSQGITNVATKRLQGRKFNIGLDWPFIAGR
                     AEIWACANVLAPIMLIEAVLLSKVGNGILPLAGIIAMGVTPALLVVTRGKLLRMIIFG
                     TLLLPLFLLSGTLIAPFATELAKGVGAFPEGVSQTQLITHSTLEGPIEKLLGWTIGNT
                     TTGDIKAILGAVVFLVFYIGIFAWYRKQMIKRNEEYAAKAK"
BASE COUNT          533 a          377 c          378 g          581 t
ORIGIN      
        1 aagtgctcta gaagaagaac tttcaaaccg tggttatgat gttcactgtg atgcagtcat
       61 ggtgaaagat gtaaacgaag accttatgaa aggttacgat atctttacac caatcgctgc
      121 aacagacctt ggttttgaac caggtatccc agttatcgaa gctgggccaa tcttattccg
      181 tatcccagca atgagcgctc cagtatttga caatattgaa gcagctatta aagaacacgg
      241 attaagctaa ttctaatttg ttaacattca tataacataa aaaagggagg aactgttatg
      301 gatgcaatct ttgacctaat cggaaaggtt ttcaatccca ttttagaaat gggtggacct
      361 gtcatcatgt taatcatttt gacagtattg gctttacttt ttggagtgaa attctccaaa
      421 gcgcttgaag gtggtatcaa acttgccatc gctcttacag gtatcggtgc tatcatcggt
      481 atgctaaatg gtgctttctc agcatcactt gcaaaattcg ttgaaaacac tggtatccaa
      541 ttgagtatta ccgacgttgg ttgggcacca ctcgcaacaa tcacttgggg ttctgcttgg
      601 acactatact tcttgctcat catgttgatt gtcaacatag tgatgctagc tatgaagaaa
      661 acagatacac ttgacgttga tatctttgat atctggcact tgtctatcac aggtctcttg
      721 attaaatggt atgctgataa caatggtgtg agtcaagggg tttcactctt tattgctaca
      781 gcagctatcg tccttgtcgg tgtgttgaaa attatcaact ctgacttgat gaaacctaca
      841 tttgatgacc ttcttaacgc cccaagttca tcaccaatga catcaactca catgaactac
      901 atgatgaacc cagttatcat ggttttggat aagatttttg aaaaattctt cccaggcctt
      961 gataaatatg actttgatgc tgctaaattg aacaagaaaa tcggtttctg gggatctaaa
     1021 ttcttcatcg gtttcatcct tggtatcgtt atcggtatta tgggaactcc acatccaatt
     1081 gcaggtgttg cagatgcaga taaatggcgt cttgttatca aaggatggtt gtctcttggt
     1141 ttgactgccg gtgtatcttt ggaactcttc tcacttatcg gttcatggtt catcgcagcc
     1201 gtagaaccac tatcacaagg tattacaaac gttgctacta aacgtcttca aggacgtaaa
     1261 ttcaatatcg gtcttgactg gccattcatc gctggtcgtg ctgaaatctg ggcttgtgcc
     1321 aacgtacttg caccaatcat gttgattgaa gcagtgcttc tttcaaaagt tggaaatggt
     1381 atcttgccac ttgcaggtat catcgctatg ggtgttactc cagctctctt ggttgtaact
     1441 cgtggtaaat tgctccgtat gattatcttc ggaacactct tgttgccact cttccttctt
     1501 tcaggtacac ttattgcacc atttgcaaca gaacttgcta aaggtgtagg tgccttccca
     1561 gaaggtgtga gccaaactca attgattact cactctactc ttgaaggacc aatcgaaaaa
     1621 cttcttggtt ggacaattgg taacactaca actggtgata tcaaagcaat ccttggtgca
     1681 gtagtcttcc ttgtattcta tatcggtatc tttgcttggt acagaaaaca aatgatcaaa
     1741 cgtaacgaag agtacgcagc aaaagcaaaa taatgcgctc ctataaaata taaactcaat
     1801 gaaaatcaaa gagcaaacta ggaaactagc cacaggttgc tcaaaacaca gttttgaggt
     1861 tgtagataa
//
LOCUS       DAVBDR010000105         1821 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.105, whole genome shotgun sequence.
ACCESSION   DAVBDR010000105 DAVBDR010000000
VERSION     DAVBDR010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1821)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1821)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1821
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.105"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            complement(<1..316)
                     /locus_tag="VQ540_002063"
     CDS             complement(<1..316)
                     /locus_tag="VQ540_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000603792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2545804.1"
                     /translation="MILSKVRCYIYNSKIRGKVLYELYEFINENKQLMDAINSIKVDS
                     SNGFSIQILHLGEQQTTVLLTDFFTKTLDLFKEFRVTNKSTLEQVKNQISILNSSGPK
                     MDL"
     gene            complement(329..1348)
                     /locus_tag="VQ540_002064"
     CDS             complement(329..1348)
                     /locus_tag="VQ540_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic biosynthesis protein"
                     /protein_id="HET2545805.1"
                     /translation="MSNTLKQLLLFREEFIKNILNGIDVDETVVIENDFVEELENFLK
                     ENDLLDFSNSIFFQLSGDKVIVNNIYPGYLAYFNRFLTFYPKIFAIKEVGEYIDFLNF
                     EKRIADMFYCWGFNANSRVLTAEKIIEIPNHQINAKYIKKVIKMSELLFGVDSNNRIR
                     LLNNRRELIKTIFQGSVIKSAIPALAATLDTISNSGSFQISLSKQIINNLVLSGKDKV
                     TIPRIELDNVVLSRQKIIVSVSYINDFLDLRFPDKIEYILNFLEGSGFNTKVMVYFGK
                     IVEEDKNYFVNLEKPQYFDFTSILFNKLFFKELNKFDYMVIEELIPNLDEDVMMTEYI
                     KEYTE"
BASE COUNT          626 a          318 c          189 g          688 t
ORIGIN      
        1 ttaaatccat ttttggacca gaagaattta gtatgctaat ttgatttttc acctgctcaa
       61 gagtactctt atttgtaacc ctaaattcct taaacaagtc taaagtttta gtaaaaaaat
      121 ctgttaataa gacagttgtt tgctgttctc ctaaatgtaa tatttgaata ctaaaaccat
      181 tactactgtc aactttaatt gaattaattg cgtccatcaa ttgcttattt tcatttataa
      241 attcatataa ttcatacaga actttacctc taattttaga attatatatg taacaacgta
      301 ctttacttaa aatcataata gattgctcct attcagtata ctcttttata tactctgtca
      361 tcattacatc ttcatcaaga tttggaatga gttcttcaat aaccatgtaa tcaaacttgt
      421 ttaattcttt aaagaataac ttattgaaaa gtatactggt aaaatcaaaa tactgaggtt
      481 tttcaagatt aacaaaatag ttcttatctt cttctacaat tttcccaaag tagaccatta
      541 ctttagtatt gaaaccagat ccttctaaaa aatttaaaat gtattctatt ttatctggaa
      601 atctcaaatc caaaaaatca tttatatacg aaactgatac aataatcttc tgtcttgaaa
      661 gaacaacatt atctaactct atcctaggaa ttgtaacttt atctttacca cttaatacta
      721 aattattaat tatctgcttt gataaagaaa tttgaaatga tccactgtta ctgattgtat
      781 ccaaagtagc agctagagca ggaattgctg acttaattac agaaccttgg aaaatagttt
      841 ttatcaattc ccttctattg ttaagcaacc gaattctgtt attactatca acaccaaaca
      901 agagttcact catttttata acttttttta tgtacttagc attgatttgg tgatttggga
      961 tttcaattat tttttcagct gtcaacactc tagaatttgc attaaatccc caacaataaa
     1021 acatatccgc aattctcttt tcaaaattta aaaagtcaat atattctcca acttctttaa
     1081 tagcgaatat tttcggataa aatgtaagga acctattaaa atatgctaaa tatcctggat
     1141 aaatattatt cactattact ttatctccag ataactgaaa aaatatgcta tttgaaaaat
     1201 ctagcaaatc attctctttt aaaaagttct ccaactcttc tacaaaatca ttttctatta
     1261 ctactgtttc atccacatca atcccattca aaatattttt tatgaactcc tctctaaaaa
     1321 gtagtaattg cttcaatgta tttgacatat attcatctgg ataatatgtt tccaaattaa
     1381 cattagcgag tctaggagct tctttgatga ttatgttaac tatatcctga actatttctt
     1441 ctgatgtccc taccttctgg tgttctctcc tgtgtttatt ataataacat tgtccgaata
     1501 gtagctgaaa aaacaaatta ctatcaaata atctcgttag aattaatagc tttcttattg
     1561 acttattatc aacttttaaa ctttcttttt caatttgcct caactctaca atgtcttgat
     1621 aaataaaatt atgttctata aaaatttact tcaactagct atggtttaat agatttttta
     1681 aaggggataa ttgtctaaaa tttaactttt tacaaatcaa gatgtctcta taaactagca
     1741 acctctctaa taactttacc cctatagcta tagacaatcg agtaggggat aatctctagc
     1801 ccctctcaca ccaccgtacg t
//
LOCUS       DAVBDR010000106         1651 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.106, whole genome shotgun sequence.
ACCESSION   DAVBDR010000106 DAVBDR010000000
VERSION     DAVBDR010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1651)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1651)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1651
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.106"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            complement(704..1651)
                     /locus_tag="VQ540_002065"
                     /pseudo
     CDS             complement(704..1651)
                     /locus_tag="VQ540_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
BASE COUNT          475 a          329 c          341 g          506 t
ORIGIN      
        1 tacgtgacag agtccagttc tatcagaccg ttcgttttac agacacaagt gaagtaggat
       61 tacttcgatt agttgtttac cccttcgctc cacttccatt acagaagttt cctcactact
      121 atgggctcgg ctgacttctc atgattcgtt gttactacgc tttcggcgct catgagacct
      181 cacgggataa gccgtacatc tttcctcgtt tatacaagat atgaggacgt taaaaggtta
      241 caatgaaaat aggaaatctg acgcagagtc tttagactct aggaagattt atctttttca
      301 catagacctt agtccgaatt caattactct cgtgatttac gcatataggt tacgactacc
      361 tttttggact ttagagtttt aagccccctt atccgctgta tacgccttac tatcacgttc
      421 ctgttcgtag agcctcgatt tcgctatccc ttcctctgac gattcttatt tcctgcgtca
      481 gacttaaaac ggtctatccc cagaccgttt taatccgcta cctcacgata gtcaggcttg
      541 ggaatcgcta ttgggttcac cggtagcagg tgcccacgga ggacttacac ctcagatgca
      601 cgacatgccc gtcgtactta aaatcagcct aaatgattca ggctgatttt tctattgatt
      661 caaaaaaacg gctctttgtc aactgtagtg ggttgaagaa aagctaagat cgagaaagga
      721 caaatttcgt cctttctttt ttgatattca gagcgataaa aatccgtttt ttgaagtttt
      781 caaagttccg aaaaccaaag gcattgtgct tgataagttt gatgagatta ttggtcgctt
      841 ccaatttggc gtttgaatag ggtagttgaa gggcgttgat aatcttttct ttatctttga
      901 ggaaggtttt aaagacagtc tgaaaaatag gatgaacctg cttcagattg tcctcaataa
      961 gtccgaaaaa tttctctggt tccttattct ggaagtgaaa aagcaagagc tgatagagct
     1021 gatagtggtg tttcaagtct tccgaatagc tcaaaagctt gtctaaaatc tctttattgg
     1081 ttaaatgcat acgaaaagta ggacgataaa aacgcttatc actcagttta cggctatcct
     1141 gttgtatgag cttccagtag cgcttgatag ccttgtattc atgggatttt cgatgaaact
     1201 gattcatgat ttaaacacgc acacgactca tagcacggct aagatgttgc acaatgtgaa
     1261 agcgatcaag aacgatttta gcattcggga gtgaaacagt ctgggagact gtttcagcct
     1321 gagcctagaa atttgaaagc gaagctgtct agctaagtca tagtaagggc taaacatatc
     1381 catagtaata attttgacgc gacatcggac aactctatcg tagcgaagaa agtgatttcg
     1441 aatgatagct tgtgttcttc cctcaagaac agtgatgata ttgagattgt taaaatcttg
     1501 cgcaatgaag ctcatctttc cctttgtaaa agcatactca tcccaagaca taatctcagg
     1561 aagacaagaa aaatcatgtt taaagtgaaa atcattgagc ttacgaatag cagttgaagt
     1621 tgagatggaa agctgctggg caatatcagt c
//
LOCUS       DAVBDR010000107         1649 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.107, whole genome shotgun sequence.
ACCESSION   DAVBDR010000107 DAVBDR010000000
VERSION     DAVBDR010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1649)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1649)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1649
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.107"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            110..409
                     /locus_tag="VQ540_002066"
     CDS             110..409
                     /locus_tag="VQ540_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000378912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic biosynthesis protein"
                     /protein_id="HET2545806.1"
                     /translation="MDSYAINFWESKGVGIDKKILEFIQKNITVIKNKNFLNKDFDIY
                     VKKIHNLFFVISTLVSKEQYMGIVSSQIHMFANRMGISPTIEVTMLDFFLREDSD"
     gene            411..1181
                     /locus_tag="VQ540_002067"
     CDS             411..1181
                     /locus_tag="VQ540_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SagB/ThcOx family dehydrogenase"
                     /protein_id="HET2545807.1"
                     /translation="MEKYFFDISIFEKIKKVLSYQSKYWEISKPRDKYSFKSQNRISG
                     SNSIKFKDFELDYELESLGKILLKRRSFLLNEFDKNASFDKLIYLLKTVFSPTNCKFV
                     FGEEVPLFSYPTSGALNSITPFVYIDNMDEVKNGIYEVKYDGLEFKKSMNIIDLETFT
                     PITSKNSDVQNNSFKKVNMIIMLCSNYENIFNKYGLLAYRLLHLEAGHIAQNIQLVST
                     ALGIKSLPMGGWFDDKIETFINEISDKKNIYLYAIAVG"
     gene            1201..1365
                     /locus_tag="VQ540_002068"
     CDS             1201..1365
                     /locus_tag="VQ540_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2545808.1"
                     /translation="MNAEDKFRELENENKLLKLHNKELENEIQNGWKFWIWVTVPILG
                     LIYAIIQKIF"
BASE COUNT          606 a          181 c          269 g          593 t
ORIGIN      
        1 agataactat tattacgaaa aaaaattctt gtgtaaaatt ctattgactt tctatattat
       61 ttttgtattt cataacgaat gtaatttaac aagtgaagaa attttaaaga tggattccta
      121 tgctattaat ttctgggaga gtaaaggggt cggtattgac aaaaaaatct tggaatttat
      181 tcaaaaaaat attacagtta ttaaaaataa aaattttttg aataaagatt ttgatattta
      241 tgttaaaaag attcataatt tattctttgt catttctact ttagtttcaa aagagcaata
      301 catggggata gtttcttccc aaatacatat gttcgcaaat aggatgggaa tttctcccac
      361 cattgaagtt accatgctag atttttttct gagggaggat tctgattaat atggaaaaat
      421 atttttttga tatttctatt tttgaaaaaa taaaaaaagt attatcatac caatctaaat
      481 attgggaaat atcgaagcct agggataagt acagtttcaa aagtcaaaat agaatatctg
      541 gctctaatag cattaaattt aaagattttg agttagatta tgaactggag tcacttggta
      601 aaatactttt aaaaaggaga tcgtttttac taaatgaatt tgataagaat gcgagttttg
      661 acaaactgat ttacttgttg aaaactgtat tctctcctac aaattgcaag tttgtatttg
      721 gagaagaggt tcctttattt agctatccta catcaggtgc gttaaattca attactcctt
      781 ttgtttatat tgataatatg gatgaagtaa agaatggtat atatgaagta aagtatgacg
      841 gacttgaatt taaaaaaagt atgaatatta tagacttaga aacatttacc ccaataacaa
      901 gtaaaaacag tgacgtacaa aataattcat ttaaaaaggt aaatatgata attatgttat
      961 gttcgaatta tgaaaatatt ttcaataaat atggattatt agcttatcga cttttgcatt
     1021 tagaggctgg tcatattgca caaaatatcc agcttgtttc tactgcgcta ggaataaaaa
     1081 gtttaccgat gggaggttgg tttgatgata aaatagaaac ttttattaat gaaattagtg
     1141 ataaaaaaaa tatttatctc tatgcaattg cagttggata aatttaagga ggaagtgtag
     1201 atgaacgcag aggataaatt tcgcgaacta gaaaatgaaa ataaacttct aaaacttcat
     1261 aacaaggagc ttgagaatga aattcaaaat ggatggaaat tttggatatg ggtaactgtc
     1321 cctattttag gtttgatata tgctattatt caaaaaattt tttaattatg ctagtttgtc
     1381 aggttgagta gtttttgttc aaaatttaat aaactttttt caatgaagat tatctaaaga
     1441 ttgcttctca gatgagaatg gcttctctat cttatataaa ttatcttcat agagtgtcct
     1501 gttattcatg ttatcacaga atagatagtt tttttggctc tataatattt gtagtgggta
     1561 aatcccctat agatattatg gagcctattt ttgtgtagaa aaaaagtccc atatcatcta
     1621 taatgaaaag caaccaaact atcattaga
//
LOCUS       DAVBDR010000108         1586 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.108, whole genome shotgun sequence.
ACCESSION   DAVBDR010000108 DAVBDR010000000
VERSION     DAVBDR010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1586)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1586)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1586
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.108"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            84..491
                     /locus_tag="VQ540_002069"
     CDS             84..491
                     /locus_tag="VQ540_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HET2545809.1"
                     /translation="MARYGVYAVIPNPEQKQIVLVQEPNGAWFLPCGEIEAGENHQEA
                     LKRELIEELGFTAEIGTYYGQADEYFYSRHRDTYYYNPAYLYEATSFKEVQKPLENFN
                     HIAWFPIDEAIQNLKRGSHKWAIESWKKQHKIG"
     gene            656..955
                     /locus_tag="VQ540_002070"
     CDS             656..955
                     /locus_tag="VQ540_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HET2545810.1"
                     /translation="MKLINTTNSHSQLVKSQLESTDATLVEVYSAGNTDVIFTQAPLH
                     YEILISNKHRAIREPEIETIQEFFLKRKIDKTSVNEANIKTLYSEKLIGISIPIK"
     gene            1216..1539
                     /gene="tnpB"
                     /locus_tag="VQ540_002071"
     CDS             1216..1539
                     /gene="tnpB"
                     /locus_tag="VQ540_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HET2545811.1"
                     /translation="MMIVLSDLGQVHLVCGKTDMRQGIDSLAYVVKTHFELDPFSGQV
                     FLFCGGRKDRFKALYWDGQGFWLLYKRFENGRLTWPSTEKDVKALTSEQVDWLMKGFS
                     ITPQI"
BASE COUNT          544 a          314 c          282 g          446 t
ORIGIN      
        1 actataataa taacgatact agataatgag gaaaatgcaa tggcaaaccc aactttcgga
       61 gaaaaaaagc gaatacagac tatattgctc gctatggcgt atatgcagtt atccctaatc
      121 ctgaacaaaa acaaattgtt cttgttcaag aaccaaatgg tgcttggttc ctaccatgtg
      181 gagaaattga agcaggtgaa aatcatcagg aagccctaaa gcgtgagttg attgaagagc
      241 ttggtttcac agcagaaatt ggtacctatt acggacaagc tgacgaatat ttctattctc
      301 gtcatcgtga tacctactac tacaatcctg cctacctcta tgaagcaact tctttcaaag
      361 aagtacaaaa gccactagaa aactttaatc atattgcctg gttccctatt gacgaggcta
      421 tccaaaacct taaacgtggt agccataaat gggccattga atcttggaaa aaacagcata
      481 agattggcta atactcttcg aaaataaaat tcaaaccacg tcagcgtcgc cttaccgtac
      541 tcaagtatag cctgcggcta gcttcctagt ttgctctttg attttcattg agtataaatc
      601 aagcgacttt attcaaaaag tgctataata gaattagaaa atcggaggaa atattatgaa
      661 gcttatcaat acgacaaact cacactcgca acttgtaaaa agtcaactag aaagtaccga
      721 tgcaaccctt gttgaggttt attctgcagg gaatacagat gttattttta cccaagctcc
      781 gcttcactat gaaatcctca tctcaaacaa acaccgtgct attcgtgagc ctgaaatcga
      841 aaccattcaa gaatttttct tgaaacgtaa aattgataag acctctgtta atgaagccaa
      901 tatcaagaca ctctactcag agaaattaat tggaatttca atcccaatca agtaagaaaa
      961 ttgagtaaaa actcgatttg agagaaagtc caataagtct ttccataaca aaacgcatag
     1021 taacaagagt ttctacaccc actattatac gtttttatca ttttgaaatc tgctgctaat
     1081 caatgaagaa gcaaagatca aactaggcag ctagttacaa gttacgtaag cgcgtcataa
     1141 caaggtatct atcctaattc cccaacttcc agtatactag ataaaaaata attatcagag
     1201 gaaaggtatt gtactatgat gattgtacta agtgatttag gtcaagttca ccttgtttgt
     1261 ggcaagacag atatgaggca gggaatagac tcattagcct atgtagttaa aacccacttt
     1321 gaattggatc ctttctccgg tcaagtcttt ctcttttgtg gtggacgtaa agaccgcttt
     1381 aaagcccttt actgggatgg tcaaggattt tggctactat ataaacgctt tgagaacggc
     1441 agactgactt ggcccagtac agaaaaggat gtcaaagctc tcacatctga acaagtagac
     1501 tggcttatga agggcttttc tatcactccc caaatatagt ggatttaaac tagaatagta
     1561 cacctctact tctaaaacat tgttag
//
LOCUS       DAVBDR010000109         1585 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.109, whole genome shotgun sequence.
ACCESSION   DAVBDR010000109 DAVBDR010000000
VERSION     DAVBDR010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1585)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1585)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1585
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.109"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            1..482
                     /locus_tag="VQ540_002072"
                     /pseudo
     CDS             1..482
                     /locus_tag="VQ540_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            632..886
                     /gene="blpM"
                     /locus_tag="VQ540_002073"
     CDS             632..886
                     /gene="blpM"
                     /locus_tag="VQ540_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000379879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit BlpM"
                     /protein_id="HET2545812.1"
                     /translation="MDTKIMEQFHEMDITMLSSIEGGKNNWQTNVLEGGGAAFGGWGL
                     GTAICAASGVGAPFMGACGYIGAKFGVDLWAGVTGATGGF"
     gene            902..1105
                     /gene="blpN"
                     /locus_tag="VQ540_002074"
     CDS             902..1105
                     /gene="blpN"
                     /locus_tag="VQ540_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit BlpN"
                     /protein_id="HET2545813.1"
                     /translation="MNTYCNINETMLSEVYGGNSGGAAVVAALGCAAGGVKYGRLLGP
                     WGAAIGGIGGAVVCGYLAYTATS"
     gene            1349..1498
                     /gene="blpO"
                     /locus_tag="VQ540_002075"
     CDS             1349..1498
                     /gene="blpO"
                     /locus_tag="VQ540_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpO"
                     /protein_id="HET2545814.1"
                     /translation="MDTKMMSQFAVMDNEMLACVEGGDIDWGRKISCAAGVAYGAIDG
                     CATTV"
BASE COUNT          520 a          218 c          365 g          482 t
ORIGIN      
        1 gacacggtaa tgattgatgc gacggaagta aaaatcaatc gccctaaaaa aaacaattag
       61 cgaatgattc tggtaaaaag aaatttcacg ctatgaaggc tcaagcgatt gtcacaagtc
      121 aagggagaat tgtttctttg gatatcactg tgaactattg tcatgatatg aagttgttca
      181 aaatgagtcg cagaaatatc ggacaagctg gtaaaatctt ggctgacagt ggttatcaag
      241 ggctcatgaa gatatatcct caagcacaaa cttcacgtaa atccagcaaa ctcaaaccgc
      301 taacagttga agataaagcc tgtaaccatg cgctatctaa ggagagaagc aaggttgaga
      361 acatctttgc caaagtaaaa acgtttaaaa tgttttcaac aacctatcga aatcatcgta
      421 aacgcttcgg attacgaatg aatttgagtg ctggtattat caatcatgaa ctaggattct
      481 agttttgcag gaagtctaat gtaatttttg caattcaaga cgtttcgatg actattcaag
      541 atctggatga aaaattttaa aaaacgatga tatactaaac ttgtcaaagt tacaacaaga
      601 caaaaattaa aaataaaaaa gagtatttgt catggataca aaaattatgg aacaatttca
      661 tgaaatggat ataactatgt tatctagtat tgaaggaggc aagaataatt ggcaaactaa
      721 tgtcttggaa ggtggtggtg ctgcttttgg tggctggggg ctagggacag ctatttgtgc
      781 tgcgagtggt gttggagcac catttatggg agcatgtgga tacataggag ctaaatttgg
      841 tgtggatctt tgggcaggag taacaggggc aacgggtgga ttttaataaa aggagacttg
      901 tatgaatact tattgtaata taaatgaaac aatgctgagt gaggtttatg gaggtaattc
      961 cggaggagca gctgtagttg ctgctttagg ttgtgcagcg ggtggagtga aatatgggag
     1021 acttctagga ccatggggcg ctgcaatagg aggaattgga ggagcagtgg tttgtggata
     1081 tttagcctat accgctacat cataaaaatg aaagctaaat tttatgaagg ctatattctt
     1141 tattattctc ttcgcttttc aaacctatct tatttatcta tccataagta tctccgataa
     1201 aaaacaaaag actattgaat taacatcatt gaattgtttt gtcatattat ttctaatcta
     1261 tgataaatta atttttctct ttattgccta tgtttttttg ataattttta tattaaactt
     1321 gttccgtaac tgaaaagtga tatactatat ggatacaaaa atgatgtcac aatttgcagt
     1381 tatggataat gaaatgcttg cttgcgttga aggtggagat attgattggg gaagaaaaat
     1441 tagttgtgca gcaggggttg catatggcgc aattgatggg tgtgcaacaa cggtttgaca
     1501 tttctattgg gaccatttgc tataggaata ggtgtaactg gtgctgcagg tggagctata
     1561 cttggaggtg tagcctatgc agcaa
//
LOCUS       DAVBDR010000110         1506 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.110, whole genome shotgun sequence.
ACCESSION   DAVBDR010000110 DAVBDR010000000
VERSION     DAVBDR010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1506)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1506)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1506
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.110"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            complement(1..114)
                     /locus_tag="VQ540_002076"
                     /pseudo
     CDS             complement(1..114)
                     /locus_tag="VQ540_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(463..855)
                     /gene="rpsI"
                     /locus_tag="VQ540_002077"
     CDS             complement(463..855)
                     /gene="rpsI"
                     /locus_tag="VQ540_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HET2545815.1"
                     /translation="MSQAQYAGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     RLVINQPFAVTSTVGSYDVFVNVVGGGYAGQSGAIRHGIARALLQVDPDFRDSLKRAG
                     LLTRDSRKVERKKPGLKKARKASQFSKR"
     gene            complement(875..1321)
                     /gene="rplM"
                     /locus_tag="VQ540_002078"
     CDS             complement(875..1321)
                     /gene="rplM"
                     /locus_tag="VQ540_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HET2545816.1"
                     /translation="MNKTTFMAKPGQVERKWYVVDATDVPLGRLSAVVASVLRGKNKP
                     TFTPHTDTGDFVIVINAEKVKLTGKKATDKIYYTHSNHPGGLKQISAGELRSKNAVRL
                     IEKSVKGMLPHNTLGRAQGMKLKVFVGAEHTHAAQQPEVLDISGLI"
BASE COUNT          438 a          294 c          295 g          479 t
ORIGIN      
        1 ctcaatagga ttgtactcag gtgagtaggg aggaagaggt aaaagtttat acccaaactc
       61 ttcacacaag agttctaact tacccattct atggaatctt gcattatcca taatatagta
      121 gattgaaact agaatagtac acctctactt ctaaaacatt gttagaattc gatttgacta
      181 tcctcggttt gtcctattct tatttcacct tactataaaa ataaggtaaa cttttcaaaa
      241 aaacacgaaa aaagcaccca tagggcaaac ctttgagtgc tttgaaacat tgatataatt
      301 gtattgatta gcgttttgag gcaactgacc ttgtcaggtt gcagccacat ttgtaagcaa
      361 ctaaagtcgc aacaactgtg tcaattgcac caatttagta agaaagtata aaaaaagaac
      421 accccgaaag gtgctctgta taagtatagt aattctttcg aattaacgtt tactaaattg
      481 tgatgcttta cgagctttct taagacctgg tttcttacgt tcaactttac gtgagtcacg
      541 tgtaagaagt cctgcgcgtt tcaatgaatc gcggaagtct gggtctactt gaagaagggc
      601 acgagcgata ccgtgacgga tagctcctga ttgaccagcg tatccaccac ctacaacgtt
      661 aacgaaaacg tcgtatgaac ctacagttga agtaactgcg aatggttggt tgatgacaag
      721 acgaaggtca gcatgtggga tgtactcttc aacatctttt ttgttaacag tgattttacc
      781 agttcctgga acaaggcgaa cgcgtgcaac agcgttttta cgacgtccag tacctgcata
      841 ttgtgcttgt gacatacttt atttgttcct ttccttagat aagtcctgaa atgtcaagaa
      901 cttctggttg ttgtgcagca tgagtgtgct cagctccaac aaatactttc aacttcatac
      961 cttgagcgcg tccaagtgta ttgtgtggaa gcataccttt aactgatttc tcaatcaaac
     1021 gtactgcatt tttagaacga agttcacctg cagagatttg tttcaatcca cctgggtggt
     1081 ttgagtgagt gtagtagatt ttatcagttg cttttttacc agtcaattta actttttcag
     1141 cattgataac aatcacgaag tcacctgtat cagtgtgtgg tgtaaatgtt ggtttgtttt
     1201 ttccgcgaag tacgctagca actactgcag aaagacgtcc aagtggtaca tcagttgcgt
     1261 caactacgta ccatttacgt tcaacttggc ctggtttagc cataaatgtt gttttgttca
     1321 tgatttctcc tatatatagt tcgatttttg tttacggtga tgggtgttcc ttcccatcga
     1381 aaagtatttg gaaggttccg gggcctttca aatggggtaa acaataccgc ctactatcat
     1441 accaaatttc acccctaaaa gtcaatagat atgaaaaata tttttcggta acttctcaaa
     1501 gtaact
//
LOCUS       DAVBDR010000111         1370 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.111, whole genome shotgun sequence.
ACCESSION   DAVBDR010000111 DAVBDR010000000
VERSION     DAVBDR010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1370)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1370)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1370
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.111"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            complement(1..380)
                     /locus_tag="VQ540_002079"
                     /pseudo
     CDS             complement(1..380)
                     /locus_tag="VQ540_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(829..1227)
                     /locus_tag="VQ540_002080"
     CDS             complement(829..1227)
                     /locus_tag="VQ540_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2545817.1"
                     /translation="MENKESHKSQEIGNLIRVYNRSKREEAESEPLNLYVEDEKGNLL
                     AGLIAETFGNWLEIEYLFVKEELRGQGIGSKLLQQAESEAKNRNCCFAFVNTYQFQAP
                     DFYQKHGYKEVFSLQDYLYIRQRYYYQKNL"
BASE COUNT          398 a          269 c          217 g          486 t
ORIGIN      
        1 gcctgtttct taagcgcttt tccttttcta gggtaaggca aatcctgctt gcttaacccc
       61 aattttccat gatgaatcca atagtaaatg gttgaaattc ccacgttaac ccctttagcc
      121 ataaccatca tttcaggcga aaatttttgg ttatgatagt ggagaatctt ttcctttagt
      181 tccttggtca agcttgattt cttgaccgag cgcttgcgat tgttttcata agactgttga
      241 gcatagtcgg cagaataaac ctctttgaag cgcccttttc caagacattg tcggactgtc
      301 ctacgcttga tttcagtgtg gatagtttga ggagcttttc caagtagaga ggcaatttct
      361 ctatttgatt tccctttgtt cgccttttgt agtataatgg ttttgcatct ctgtgccttt
      421 cttgtgtttg tggttgaaca acaagtataa cacaaaggtg ttttcttatg cctacaagag
      481 ctttcattat ttccattttc ttttggattt cactctattc tgaaaaactt gtgtatattt
      541 actgaagcta gcaagtctta cctgtaaatt taatgaaagc aacacaaaat ccgagagggg
      601 aatctcggat taatgtcaat ttaaaaagat agagagtttt tagtttaaat aaattgtttt
      661 aaaatatcaa caacatcact tcttttctta acctgataag ccttgattcc taattttggg
      721 gctacgatta tattgtcctc aatatcgtct agaaagacac aatttctagg ttataactgg
      781 tatttatcga tagttactca tatatatcag tccacctcca tactcacctt acagattctt
      841 ttgataataa tatctttgcc taatgtagag atagtcttgc aaagaaaaaa cttccttgta
      901 gccatgtttc tgataaaagt ccggtgcctg gaactggtaa gtattgacaa aggcaaaaca
      961 acaatttcga ttcttagctt cactttctgc ctgttgcaat agttttgaac cgattccttg
     1021 ccctcgcagt tcctctttta caaacaaata ctcgatttct agccaatttc caaaagtctc
     1081 tgctatcaaa cccgcaagga gattgccctt ttcatcttcg acataaagat taagtggctc
     1141 actttcagcc tcttctcttt ttgaacggtt ataaacacga atcagattcc ctatttcttg
     1201 cgatttatgt gattccttat tttccaatct aaagtataat gaaatgaaat aaaacatgcg
     1261 caaatcgatt aaggaattta atctaatttc taacaatgtc ttagaaatca aagtgtacta
     1321 ttttaacttc aatgcactat acatctaata ctcaataaaa atcaaagagc
//
LOCUS       DAVBDR010000112         1326 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.112, whole genome shotgun sequence.
ACCESSION   DAVBDR010000112 DAVBDR010000000
VERSION     DAVBDR010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1326)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1326)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1326
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.112"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            236..676
                     /locus_tag="VQ540_002081"
     CDS             236..676
                     /locus_tag="VQ540_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000861967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET2545818.1"
                     /translation="MKVELQISETYEEEKLIVQAPQPTDKVQKVIEFAENLDQREKIK
                     GKIDDQVYLVEIGKIQRFYIENRKVLAETASQTYSIDLRLYQVLKLLPTNFIQISQSE
                     IINIDSISHLKLTPNGLVEIFLKNESFTYSSRRYLKTIKEKLEL"
     gene            673..1131
                     /locus_tag="VQ540_002082"
     CDS             673..1131
                     /locus_tag="VQ540_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3021 domain-containing protein"
                     /protein_id="HET2545819.1"
                     /translation="MKKQVFHDAAAGVLIGLILSILFSLIYAPNTYAPLNPYSLIGQV
                     MDQHQVHGALVLLYCTLIWAAIGMLFNFGNRLFSRDWSMLRATLTHFFLMLAGFVPLA
                     TLAGWFPFHWIFYLQLIIEFAIVYLIIWAILYKREAKKVDHINQLLEHRK"
BASE COUNT          421 a          288 c          249 g          368 t
ORIGIN      
        1 ccttgccaga gggagtaaaa tagtggtata ctcaataaaa atcaaagagc aaactagaaa
       61 gctaggcgca gacagctcaa aacactgttt tgaggttgta gataaaactg acaaagtcaa
      121 caactatcct acggcaagac gacgctgacg tggtttgaag agatttttga agagtattaa
      181 taaaggtgta caagaagtga gattaatttt gtatgaaaaa caaggagaga aatttatgaa
      241 agtagaatta cagattagtg agacttacga ggaggaaaag ctgattgtcc aagcacctca
      301 gccgacagat aaagttcaga aagtcatcga gttcgcagaa aatctggacc aaagagaaaa
      361 aatcaaaggg aaaatcgatg atcaggtcta tctagttgag attggcaaga ttcagcgctt
      421 ctatatcgag aatcggaagg ttctagcaga aaccgcgagt cagacctaca gcattgattt
      481 gcgactctat caggttctta aactcttgcc aaccaatttt atccaaattt cccaatcaga
      541 aatcatcaat atcgattcca tctctcacct caagctcacg ccaaacggtc tggtagaaat
      601 tttcttgaaa aacgaaagct tcacctactc ttcacgccgt tatctaaaaa ccatcaagga
      661 gaaattagaa ctatgaaaaa acaagtattt cacgatgcag ctgccggtgt tcttatcggc
      721 ctcatcctct ctatcctctt ttcactcatt tatgcaccaa atacctacgc accactaaat
      781 ccctactctc tcatcggcca agtgatggat cagcatcagg ttcacggtgc cttggtcttg
      841 ctctactgca cacttatctg ggcagccatt ggtatgctct tcaactttgg caatcgctta
      901 ttcagccgtg actggagcat gcttcgtgcc actctgactc atttcttcct tatgctggct
      961 ggctttgtcc cactagcaac tcttgctggt tggttccctt tccactggat tttctacctc
     1021 cagctcatta tcgagtttgc gattgtctat ctcatcatct gggctattct ctataaaaga
     1081 gaggctaaaa aagtagatca catcaatcaa ctcttggagc atagaaaata ggaacctcat
     1141 aataagcaaa tccgagaaag aaacttctcg gtttttcttt atcctgctgc accttactat
     1201 agtgaaatga aataagaaca ggataaatcg atcaggacag tcaaatcgat ttctaacaat
     1261 gttttagaag cagaggtgta ctattctagt ttcaatcctc tatatcataa cagttatttc
     1321 agatct
//
LOCUS       DAVBDR010000113         1114 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.113, whole genome shotgun sequence.
ACCESSION   DAVBDR010000113 DAVBDR010000000
VERSION     DAVBDR010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1114)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1114)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1114
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.113"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            2..>1114
                     /locus_tag="VQ540_002083"
     CDS             join(2..341,341..>1114)
                     /locus_tag="VQ540_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611423.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HET2545820.1"
                     /translation="MVKLIDRYGIEIVKKGKNRHYSSKLKQEMMDKALLEGCSQRSIS
                     LDYALPNQGMLSFWPAQYKKNGYTIVEKTRGRPAKMGRKRKKTWEEMTELERLQEENE
                     RLRTEVAYLKKFKRVRGKGRSPRARKAETVREMVSGGFRLDFLLETARLARSTYYYQL
                     KQLDGVDKDKEIKTEIQGIDNEHKGNYGYRRIHLELRNRGFVVNHKKVQRLMRILGLT
                     ARIRRKRKYSSYQGEIGKKAENLIQRQFEASRPMEKCYTDVTEFAIPNSTQKLYLSPV
                     LDGFNSEIIAYHLSTSPNLEQVKSMLEQAFTEKYYENTILHSDQGWQYQHDSYHRFLE
                     SKGIQASMSRKGNSPDNGMMESFFGILKSEMFYGYEK"
BASE COUNT          392 a          193 c          254 g          275 t
ORIGIN      
        1 catggtgaaa ttaattgacc gttatggcat agaaatcgtt aaaaaaggga agaatcgtca
       61 ctattcttct aaattgaaac aagaaatgat ggataaagcc ttactggaag gttgttcaca
      121 aagaagtatt agtcttgatt atgccctccc aaaccaagga atgctttcat tttggccggc
      181 acaatacaag aaaaacgggt atactattgt tgagaaaaca agagggagac cagctaaaat
      241 gggacgtaaa cggaagaaga cttgggaaga aatgacagaa ctagaacgac tccaggagga
      301 gaatgaacgc ttacggactg aggtggccta cctaaaaaag ttaaaagagt tagaggaaag
      361 ggacgaagcc ctagagcgag aaaggcagag acagttagag aaatggtttc aggaggattt
      421 cgactagatt ttcttcttga aacagcacgt ttagctcgct cgacttacta ttatcagttg
      481 aaacaactgg atggggttga taaagataaa gagattaaaa ccgaaattca gggcattgat
      541 aatgaacata aaggcaacta tggctatcgt cgaatccatt tagaactaag gaatcgtggt
      601 tttgtggtca atcataagaa agttcaacgg ttgatgagaa ttcttggttt aacggctcga
      661 attcgccgta aacggaagta ttcttcctac caaggagaga ttggcaagaa agcagagaat
      721 ctcattcaac gccagttcga agcatcgagg ccaatggaaa agtgctatac agatgtgaca
      781 gagtttgcca ttccaaatag cacacagaaa ctctatttat caccagtttt agatggtttt
      841 aacagtgaaa tcattgctta tcatctttct acttcgccaa acttagaaca agtgaagagt
      901 atgttagaac aggcctttac agagaaatac tatgagaata cgattctcca tagtgaccaa
      961 ggctggcaat accaacacga ttcttatcat cggttcctag agagtaaggg aattcaagca
     1021 tccatgtcac gcaagggcaa cagcccagac aacggcatga tggaatcttt ctttggcatt
     1081 ttaaaatccg aaatgtttta tggctatgag aaga
//
LOCUS       DAVBDR010000114         1054 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.114, whole genome shotgun sequence.
ACCESSION   DAVBDR010000114 DAVBDR010000000
VERSION     DAVBDR010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1054)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1054)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1054
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.114"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            <1..555
                     /locus_tag="VQ540_002084"
     CDS             <1..555
                     /locus_tag="VQ540_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HET2545821.1"
                     /translation="KDETTSYPIYEIPEAWRYIKFASLVNFRIGKTPPRSEATFWGTE
                     IPWVSISDMPISGYVTNTRESISKLALKSKKIDISPKGTLLMSFKLSIGKVAILDIPA
                     THNEAIISIFPYANKENIIRDYLMIFLPLISTLGDSKDAIKGKTLNSTSISELLIPIS
                     NHEEMKRIISKVDLLFQKVSQLFE"
     gene            complement(503..1048)
                     /locus_tag="VQ540_002085"
     CDS             complement(503..1048)
                     /locus_tag="VQ540_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001104691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HET2545822.1"
                     /translation="MNWVVIKIKDIFSINTGLSYKKGDLSINNKGVRIIRGGNIKPLE
                     FSLLDNDYYIDTQFISSEQVYLKHNQLITPVSTSLEHIGKFARIDKDYDGVVAGGFIF
                     QLTPFESSEIISKFLLFNLSSPLFYKQLKAITKLSGQALYNIPKTTLSELLIPLAPFE
                     EQELITQKVEKLFEKVNQLWK"
BASE COUNT          380 a          165 c          153 g          356 t
ORIGIN      
        1 aaagacgaaa caacctctta tcctatatat gaaatcccag aagcatggag atatattaaa
       61 tttgctagcc tagttaactt cagaatagga aaaactcctc cacgcagtga agctactttt
      121 tggggaactg aaataccttg ggtatctata tcagatatgc ctatatctgg ttatgtaact
      181 aatacgagag aatctatttc taaattagca ttaaaatcaa agaaaataga catttcacct
      241 aaaggaactt tattaatgag ttttaaatta tctattggaa aagttgccat attggatatt
      301 cctgccactc ataatgaagc cattatatcg atattcccct atgctaataa agaaaatatt
      361 atcagagatt acttaatgat atttttgcca cttatctcta ctttaggtga ttcaaaagat
      421 gctataaaag ggaaaacatt aaatagtacc agtatctccg aattattaat ccctatttct
      481 aatcatgaag agatgaaaag aatcatttcc aaagttgatt tactttttca aaaagtttct
      541 caactttttg agtaataagt tcctgttcct caaaaggagc taacggaatt aatagctcgc
      601 ttagtgtagt tttaggaata ttatataaag cttgacctga tagtttagtt attgctttca
      661 attgtttata aaataacgga gaggacaagt taaataatag aaattttgaa ataatctctg
      721 aactttcgaa tggtgttaat tggaaaataa atccaccagc cacaacacca tcatagtctt
      781 tatcgattct tgcaaacttt ccaatatgtt ctaaagaggt tgatacaggt gttattagct
      841 gattatgttt taaataaact tgctcagagg agatgaattg tgtatcaatg tagtaatcat
      901 tatccaacag agaaaattct aaaggcttaa tattaccacc acgtataatt ctaacacctt
      961 tattattaat gcttaaatcg cccttcttgt aagaaagacc tgtatttatt gaaaaaatat
     1021 cttttatttt tataacaacc caattcatag gtat
//
LOCUS       DAVBDR010000115         1042 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.115, whole genome shotgun sequence.
ACCESSION   DAVBDR010000115 DAVBDR010000000
VERSION     DAVBDR010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1042)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1042)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1042
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.115"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            91..>1042
                     /locus_tag="VQ540_002086"
     CDS             91..>1042
                     /locus_tag="VQ540_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HET2545823.1"
                     /translation="MQEHYTPKGKHLTIDNRRLIERWKNENKSNREIAGLLGKAPQTI
                     HNEVKRGTTLQQVRKGLYKKVYSADYAQTVYQFNRKRSVKKLILTKEIREKILHYHKQ
                     KFSPEMMVNKKQVKVGISTIYYWFHNGHLGLTKADMLYPRKRKGVKKQASPNFKPAGK
                     SIEERPDVINLRLENGHYEIDTVLLTKIKNYCLLVLTDRRSRHQIIRLIPNKTAESVN
                     QALTLLLGEHRILSITADNGSEFKRLSEVFPEEHIYYAHAYSSWERGSNENHNRLIRR
                     WLPKGTKKTTPKEVAFIENWINNYPKKCLDYKSPSEFLLGG"
BASE COUNT          370 a          187 c          215 g          270 t
ORIGIN      
        1 ctgttgtcaa atgaaatgtg atttaaggta taagaaaaca cctctgtgct atacttgttg
       61 ttcaccacaa acacaaggaa aggcacagag atgcaagaac attatacccc aaaagggaaa
      121 catttgacaa tagataaccg tcgcttgatt gagcggtgga agaatgaaaa taagtccaat
      181 cgtgaaattg caggcttgtt aggaaaggcg cctcaaacga ttcataatga agtcaaaaga
      241 ggtacaactt tacaacaagt gagaaaaggg ctatacaaaa aggtctattc tgccgattac
      301 gcacaaactg tttaccaatt caatcgaaaa cggtcggtga aaaagttaat tttaacaaag
      361 gaaatcagag agaagatctt acactatcat aagcaaaaat tttcgcctga aatgatggtt
      421 aacaagaagc aagtgaaagt tggtatttca accatctact actggtttca taatggtcat
      481 ttaggattga cgaaggccga catgctttat cccagaaaaa ggaaaggtgt caagaagcaa
      541 gctagtccga actttaagcc ggcaggtaaa tctatcgaag aacgtcctga cgttattaat
      601 cttcgcttgg aaaatggtca ttatgaaatt gataccgtcc tactgactaa gataaaaaat
      661 tattgcctgt tagtcttaac cgaccggcgg agcagacacc aaattataag gttaattcca
      721 aataaaactg ctgaatctgt caatcaggcg cttacgttac tattagggga gcatcgtatt
      781 ctgtccatta ctgcagataa tggttcggag ttcaaacgat tgtctgaggt atttcctgag
      841 gaacatatct actacgcaca tgcttactct tcatgggaga gaggttcaaa tgaaaatcat
      901 aatcgattaa ttcggagatg gttacctaaa ggaaccaaga aaacgactcc gaaagaagta
      961 gcttttatcg aaaattggat taacaactac cctaaaaaat gcttggacta caagtcgcca
     1021 agtgaatttc ttttgggtgg ct
//
LOCUS       DAVBDR010000116         1035 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.116, whole genome shotgun sequence.
ACCESSION   DAVBDR010000116 DAVBDR010000000
VERSION     DAVBDR010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1035)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1035)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1035
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.116"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            complement(<1..990)
                     /gene="ltrA"
                     /locus_tag="VQ540_002087"
     CDS             complement(<1..990)
                     /gene="ltrA"
                     /locus_tag="VQ540_002087"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HET2545824.1"
                     /translation="MSKLLDKILSRDNMLEAYNQVKSNKGSAGIDGITIEEMDGYLRQ
                     NWRLTKELIKQRKYKPQPVLRVEIPKPNGGIRQLGIPTVMDRMIQQAIVQVISPICEP
                     HFSDTSYGFRPNRSCEKAIMKLLEYLNDGYEWIVDIDLEKFFDTVPQDRLMSLVHNII
                     EDGDTESLIRKYLHSGVIINGQRYKTLVGTPQGGNLSPLLSNIMLNELDKELEKRGLR
                     FVRYADDCVITVGSEAAAKRVMYSVSRFIEKRLGLKVNMTKTKITRPRELKYLGFGFW
                     KSSDGWKSRPHQDSVWRFKLKLKKLTQRKWSIDLTRRIEQLNLSIRGWINYFSL"
BASE COUNT          270 a          226 c          183 g          356 t
ORIGIN      
        1 caatgagaaa tagtttatcc atcctcgaat agacaaattc agttgctcaa tacgtcttgt
       61 taggtctata ctccatttcc tctgtgttag tttcttcaat ttaagcttaa atctccaaac
      121 actatcttga tgtggacgac ttttccaacc atctgatgat ttccagaacc cgaaacctag
      181 atatttcaac tctcttggtc tggtaatctt agtcttggtc atgtttactt tcagacctag
      241 ccgtttctca ataaaacgac tgactgaata catcacacgc ttagcggctg cctcgcttcc
      301 gaccgtaatc acacaatcgt ctgcgtagcg aacaaatcga agccctctct tttctaattc
      361 cttgtccaat tcattaagca tgatattgga taagagagga gataaatttc ctccctgtgg
      421 cgtgccaact agcgttttat aacgttgacc gttaatgata acacctgaat gaagatattt
      481 acgaatcaag gattccgtat ctccgtcttc gataatgtta tgtactaagg acatcaatct
      541 atcttgagga actgtatcga aaaatttctc taggtctatg tccactatcc actcatagcc
      601 gtcatttaag tactctaaga gcttcatgat ggctttttca catgacctat ttggtctgaa
      661 tccatagctc gtatctgaga aatggggttc acaaataggg ctaataactt gaacaatggc
      721 ctgttgaatc attctatcca taactgttgg aattcctagt tggcggatgc ctccgtttgg
      781 tttgggaatc tcaactctaa gaactggttg aggcttatat tttctctgtt ttatcagttc
      841 cttagtcagg cgccagtttt gtctgagata gccatccatc tcttcgatag taattccatc
      901 aatcccagct gagcctttat tagattttac ttgattgtag gcttcaagca tattgtcgcg
      961 tgataatatt ttatctagca attttgacat gtgcctattc ctttcttgtt ttggtgcctg
     1021 agggacatct tatat
//
LOCUS       DAVBDR010000117          965 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.117, whole genome shotgun sequence.
ACCESSION   DAVBDR010000117 DAVBDR010000000
VERSION     DAVBDR010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 965)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 965)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..965
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.117"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            complement(<1..>965)
                     /locus_tag="VQ540_002088"
     CDS             complement(<1..>965)
                     /locus_tag="VQ540_002088"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2545825.1"
                     /translation="AEALVEADSDALVEADSDAEVLAEAEALVDAEAEALVLAEADAL
                     VLAEAEALVDADSDAEVLAEAEALVLAEADALVDAEAEALVDAEAEALVDADSEADVL
                     AEADALVDADSDALVDAEAEALVDADAEALVLAEADALVLAEAEALVDAEAEALVLAE
                     ADALVEAEADALVDAEAEALVLAEADALVDADADALVDADSDAEILAEAEAEALVDAE
                     ADALVLAEADALVLAEADALVDADSEADVLAEAEALVDAEAEALVEAEADALVDAEAD
                     ALVLAEAEALVDAEAEALVLAEAEALVDAEAEALVDAEADALVDA"
BASE COUNT          236 a          315 c          220 g          194 t
ORIGIN      
        1 tcagcgtcga caagtgcgtc agcctcagca tcgacaagcg cttcagcttc agcgtcgaca
       61 agtgcttcgg cttcagcaag caccagtgcc tcggcttcag cgtcgacaag tgcctcagct
      121 tcagcaagta ccagtgcgtc agcctcagca tcaacgagtg cgtcggcttc agcctcaacg
      181 agtgcttcag cttcagcatc aacgagtgct tcggcttcag caagcacatc agcttctgaa
      241 tcagcatcaa ccagtgcatc agcctcagca agcaccagtg cgtcggcttc agcaagtaca
      301 agtgcgtcag cctcagcatc aacaagtgcc tcagcttcag cctcagcaag tatctcagcg
      361 tctgaatctg catcaaccag tgcgtcagca tccgcatcaa cgagtgcatc agcttcagca
      421 agcaccagtg cttcagcttc agcatcaaca agtgcatcag cttcggcctc aacaagtgcg
      481 tcagcttcag caagcaccag tgcttcggct tcagcgtcga caagtgcctc agcttcagca
      541 agtaccagtg cgtcagcctc agcaagtact agcgcctcag catcagcgtc aacaagtgct
      601 tcggcttcag cgtcaacgag tgcgtctgag tcagcatcaa cgagtgcgtc agcctcagca
      661 agcacatcag cttctgaatc cgcatcaaca agtgcttcag cctcagcgtc aacaagtgct
      721 tcagcttcag catcaaccag tgcatcagct tcagcaagta ctagcgcctc agcttcagca
      781 agcacctcag cgtctgaatc ggcatcaacg agcgcctcag cttcagcaag taccagtgcg
      841 tcagcctcag caagtaccag tgcttcagcc tcagcgtcga caagtgcctc ggcttcagca
      901 agtacctcag cgtctgaatc ggcctcaacc agtgcatctg aatcggcctc aaccagtgcc
      961 tcagc
//
LOCUS       DAVBDR010000118          902 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.118, whole genome shotgun sequence.
ACCESSION   DAVBDR010000118 DAVBDR010000000
VERSION     DAVBDR010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 902)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 902)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..902
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.118"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            122..590
                     /locus_tag="VQ540_002089"
                     /pseudo
     CDS             122..590
                     /locus_tag="VQ540_002089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817843.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT          331 a          135 c          166 g          270 t
ORIGIN      
        1 gagaagagga ttgccatctt ctccattttt atgtgcagag ttatagtggc ttgatgctgg
       61 gaaagtacac tgtgactgct aaaacattcc tagaagctgc tttgatttcc ctaatctatt
      121 tatgcaaatt ttatgttatt ttactataac agttgttgct aagccaaata atagtgggga
      181 agttcattta gacgtaagca ttgaagataa tcagggaggt agtgggtata atttcagttc
      241 tgtttcaagt agctcacaaa cagctaaata tgaaggaact ggttataata acaattcatc
      301 attatatata acgattgata aaacgtctga tgcaacagct cttttgaaat taaagttgaa
      361 taatgttgat aatcaacctg ctactgaagt tcctagttca ggaattactg taaaattaaa
      421 tgctaaagat aatgctggaa actggacaag tgcttcgaat aaagacaagt gcttcgaata
      481 aaaaagaaat aacagtaaaa attgtttctg ctaaaccgac atatccagac aaaatcttag
      541 tgaaaaatcc tgataatata aaagatacag aaaaaaatgc cattattgaa aaattgaaag
      601 aggcaaataa aaatcatcca gcaggagctc caacctttgc taaaggtgaa ggagagcatg
      661 caaatgatat tgtagcaact tattcagatg gtacaactta ttatgtaccg ttaaatgatg
      721 tgacaaaata tgcgaggtag tggctgtacc actcacttat tcacctcccc gtgatttgta
      781 gtagtgatag gctttctcac tattattata aaacaaaata aagatcacaa cactttttca
      841 ttctgtgttg tgccttgagt gaaacgaaag gaatgaatta taaatatgaa aagtatagtc
      901 ac
//
LOCUS       DAVBDR010000119          830 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.119, whole genome shotgun sequence.
ACCESSION   DAVBDR010000119 DAVBDR010000000
VERSION     DAVBDR010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 830)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 830)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..830
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.119"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            21..830
                     /locus_tag="VQ540_002090"
                     /pseudo
     CDS             21..830
                     /locus_tag="VQ540_002090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558050.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5-like element IS1515 family transposase"
BASE COUNT          266 a          174 c          162 g          228 t
ORIGIN      
        1 aaaagtgtta tactattttt atggaaacag tatacgacaa agcacaaaaa cttaactcaa
       61 aaaacttcaa actattgatt ggtgtcaaaa aggaaacctt tcaactcatg ctagaacacc
      121 tgaattcagc ctatcagatt cagcaccgaa aaggtggacg tccacgtagt ctgcccatgg
      181 aagaccagct cattatgacc ctccgttact tgcgatatta tcccactcag cgtctgctgg
      241 cctttgattt tggcgtcggt gtagctacgg taaatgccat catcacttgg gtggaggata
      301 cacttcgtgc gtcaggtagc tttgatttgg accatttaga agccccgagt gctgctgtgg
      361 ctattgacgt gaccgaaagt ccgattcagc gtccaaaaaa aaccaaagca aaaattattc
      421 tggtaaaaag aaacgacaca ccttaaaaac tcaaattatg ctggatttga cgacacataa
      481 agtctgtcaa atggcctttt ctgacggaca tacgcatgat tttactctct tcaaagaaag
      541 tattggacaa agtttgcctg aaacgacgct tgcctttgtt gacctaggtt atttaggcat
      601 cttgaaattt catgagaata ctttcattcc tgctaaaaat tccaaaaatc gccgcctgag
      661 tgaggatgat aagcagttaa ataaagagat gtcagcgata cgaattgaaa ttgaacattt
      721 taacgctaaa ttcaagacct tccaaatcat gtcagtccct tatcgtaacc gcagaaaacg
      781 tttcgagtta cgggcggaat taatttgtgc catcatcaat tatgaagtga
//
LOCUS       DAVBDR010000120          805 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.120, whole genome shotgun sequence.
ACCESSION   DAVBDR010000120 DAVBDR010000000
VERSION     DAVBDR010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 805)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 805)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..805
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.120"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            <1..>805
                     /locus_tag="VQ540_002091"
     CDS             <1..>805
                     /locus_tag="VQ540_002091"
                     /inference="COORDINATES: protein motif:HMM:NF027957.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HET2545826.1"
                     /translation="PSVSNPGTTNTNTSNNSNTNSQASQSNDIDSLLKQLYKLPLSQR
                     HVESDGLVFDPAQITSRTARGVAVPHGNHYHFIPYEQMSELEKRIARIIPLRYRSNHW
                     VPDSRPEQPSPQSTPEPSPSLQPAPNPQPAPSNPIDEKLVKEAVRKVGDGYVFEENGV
                     SRYIPAKDLSAETAAGIDSKLAKQESLSHKLGAKKTDLPSSDREFYNKTYDLLARIHQ
                     DLLDNKGRQVDFEALDNLLERLKDVSSDKVKLVDDILAFLAPIRHPERLG"
BASE COUNT          263 a          182 c          156 g          204 t
ORIGIN      
        1 taccttctgt aagcaatcca ggaactacaa atactaacac aagcaacaac agcaacacta
       61 acagtcaagc aagtcaaagt aatgacattg atagtctctt gaaacagctc tacaaactgc
      121 ctttgagtca acgccatgta gaatctgatg gccttgtttt cgacccagcg caaatcacaa
      181 gtcgaaccgc cagaggtgta gctgtccctc atggtaacca ttaccacttt atcccttatg
      241 aacaaatgtc tgaattggaa aaacgaattg ctcgtattat tccccttcgt tatcgttcaa
      301 accattgggt accagattca agaccagaac aaccaagtcc acaatcgact ccggaaccta
      361 gtccaagtct gcaacctgca ccaaatcctc aaccagctcc aagcaatcca attgatgaga
      421 aattggtcaa agaagctgtt cgaaaagtag gcgatggtta tgtctttgag gagaatggag
      481 tttctcgtta tatcccagcc aaggatcttt cagcagaaac agcagcaggc attgatagca
      541 aactggccaa gcaggaaagt ttatcgcata agctaggagc taagaaaact gacctcccat
      601 ctagtgatag agaattttac aataagactt atgacttact agcaagaatt caccaagatt
      661 tacttgataa taaaggtcga caagttgatt ttgaggcttt ggataacctg ttggaacgac
      721 tcaaggatgt ctcaagtgat aaagtcaagt tagtggatga tattcttgcc ttcttagctc
      781 cgattcgtca tccagaacgt ttagg
//
LOCUS       DAVBDR010000121          692 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.121, whole genome shotgun sequence.
ACCESSION   DAVBDR010000121 DAVBDR010000000
VERSION     DAVBDR010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 692)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 692)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..692
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.121"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            complement(74..147)
                     /locus_tag="VQ540_002092"
     tRNA            complement(74..147)
                     /locus_tag="VQ540_002092"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(111..113),aa:Arg,seq:acg)
     gene            complement(157..242)
                     /locus_tag="VQ540_002093"
     tRNA            complement(157..242)
                     /locus_tag="VQ540_002093"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(206..208),aa:Leu,seq:taa)
     gene            complement(250..321)
                     /locus_tag="VQ540_002094"
     tRNA            complement(250..321)
                     /locus_tag="VQ540_002094"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(287..289),aa:Gly,seq:gcc)
     gene            complement(344..416)
                     /locus_tag="VQ540_002095"
     tRNA            complement(344..416)
                     /locus_tag="VQ540_002095"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(381..383),aa:Thr,seq:tgt)
     gene            complement(435..516)
                     /locus_tag="VQ540_002096"
     tRNA            complement(435..516)
                     /locus_tag="VQ540_002096"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(480..482),aa:Leu,seq:tag)
     gene            complement(522..594)
                     /locus_tag="VQ540_002097"
     tRNA            complement(522..594)
                     /locus_tag="VQ540_002097"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(559..561),aa:Lys,seq:ttt)
     gene            complement(619..691)
                     /locus_tag="VQ540_002098"
     tRNA            complement(619..691)
                     /locus_tag="VQ540_002098"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(656..658),aa:Asp,seq:gtc)
BASE COUNT          179 a          205 c          149 g          159 t
ORIGIN      
        1 cgaacctgcg acaccttggt cccaaaccaa gtactctacc aagctgagct acttcccgag
       61 ttaaatagaa aaatgcaccc tagaggagtc gaacctctaa ccgcctgatt cgtagtcagg
      121 tactctatcc agttgagcta agggtgctcc atattatgcc gaggaccgga atcgaaccgg
      181 tacgatcgtt accaatcgca ggattttaag tcctgtgcgt ctgccagttc cgccaccccg
      241 gcctctctaa gcgaacgacg ggattcgaac ccgcgacccc caccttggca aggtggtgtt
      301 ctaccactga actacgttcg cactgttttc ttctatctaa aaatgccggc tacatgactt
      361 gaacacgcga ccctctgatt acaaatcaga tgctctacca actgagctaa gccggctcat
      421 ttgttatatc ttaatgcggg ttaagggact tgaaccccca cgccgttaag cgccagatcc
      481 taaatctggt gcgtctgcca attccgccaa acccgcatat atgacccgta ctgggctcga
      541 accagtgacc cattgattaa aagtcaattg ctctaccaac tgagctaacg agtctaaaat
      601 aacttgcgtt accttaaacg gtcccgacgg gaatcgaacc cgcgatcttc gccgtgacag
      661 ggcgacgtga taaccgctac actacgggac ct
//
LOCUS       DAVBDR010000122          685 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.122, whole genome shotgun sequence.
ACCESSION   DAVBDR010000122 DAVBDR010000000
VERSION     DAVBDR010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 685)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 685)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..685
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.122"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            complement(1..175)
                     /locus_tag="VQ540_002099"
                     /pseudo
     CDS             complement(1..175)
                     /locus_tag="VQ540_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000433508.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(270..455)
                     /locus_tag="VQ540_002100"
                     /pseudo
     CDS             complement(270..455)
                     /locus_tag="VQ540_002100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            459..685
                     /locus_tag="VQ540_002101"
                     /pseudo
     CDS             459..685
                     /locus_tag="VQ540_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000927991.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          200 a          122 c          135 g          228 t
ORIGIN      
        1 ttgacaatct tctctttatc tttgaggaag gttttagagg atgaacctga ttcagattgt
       61 cctcaatgag tccgaaaaat ttgtcaggct ccttattctg aaagtgaaaa agcaagagtt
      121 gatagagatt atagtggtgt ttcaagtctt ctgaatagct caaaagttta tctatagtag
      181 attgaaacta gaatagtaca cctctgcttc taaaacattg ttagaaatcg atttgactgt
      241 cctgaatgat ttgtcctgtt attatttcat tttactataa atccacgttt acgaatctct
      301 ttccacactt gttcaatggg gttcatctct ggtgtgtatg gaggaataaa tgcaaaacca
      361 atattagtcg gaatctttaa ggtacttgat ttatgccata tagcattgtc cataacgagt
      421 aaaagataat catctggata agcttgtgaa agctcctatt cctaaagccc ctttataacc
      481 tcttgcgaga gagactattg actcagccct tacttcatgc ggatgaaact tcttatcggg
      541 ttctagagag tcatagccat ctgacctact attggacctt tttgtctggg aaagttgaga
      601 atcaagcaat cacgctgtac catcatgatc agagtcggag tggttcggta gtacaagaat
      661 tcctaggaga ttattctggc tatgt
//
LOCUS       DAVBDR010000123          650 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.123, whole genome shotgun sequence.
ACCESSION   DAVBDR010000123 DAVBDR010000000
VERSION     DAVBDR010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 650)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 650)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..650
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.123"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            101..265
                     /locus_tag="VQ540_002102"
     CDS             101..265
                     /locus_tag="VQ540_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2545827.1"
                     /translation="MKKKILIIFVLYLIMSIFLYPLRESAWYQLFYTIAYVIAVMIYF
                     AINKKKGEKK"
     gene            262..>650
                     /locus_tag="VQ540_002103"
     CDS             262..>650
                     /locus_tag="VQ540_002103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000846948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein"
                     /protein_id="HET2545828.1"
                     /translation="MKTFFAKKRNIFLARLFLGQLPLLVSTYLFLSRQFLNFSVVFQF
                     LLVVINLASILVTVYLTREMRIREFEDDDLVSPRTNQLMFIGLTGFMSIICLYRGITA
                     GESYQQIIAYIGAVLCLIIMLLLMWGL"
BASE COUNT          184 a          103 c          119 g          244 t
ORIGIN      
        1 atttatgatt tgagtgatcc aaggtcaaaa taagtgctat actagcagtg taaatgttct
       61 tgctcaacta agataaatcg cacatttagg aggaaatctt atgaagaaaa aaatactgat
      121 tattttcgtt ctgtatctaa tcatgtccat ctttctatat ccgcttaggg agagtgcttg
      181 gtatcagcta ttttatacca tagcctatgt gattgcagtt atgatctatt ttgctatcaa
      241 taaaaagaaa ggagaaaaga aatgaaaact ttttttgcta aaaaacggaa catcttcctt
      301 gcgagattgt tcttaggtca gttgcccttg cttgtttcta cttatctatt tctatctcgt
      361 cagtttttaa atttttccgt agttttccaa tttcttttag tagttattaa cttggcttct
      421 attttggtta ctgtttatct cactagggaa atgaggataa gagagtttga agatgatgat
      481 ttggttagtc ctagaaccaa tcaacttatg ttcatcggct tgacaggttt tatgtctatt
      541 atttgtttgt atagaggtat cacagcagga gaatcctacc aacaaataat cgcttatatt
      601 ggcgctgttc tctgcttaat catcatgctt ctgctcatgt ggggcttgaa
//
LOCUS       DAVBDR010000124          611 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.124, whole genome shotgun sequence.
ACCESSION   DAVBDR010000124 DAVBDR010000000
VERSION     DAVBDR010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 611)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 611)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..611
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.124"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            complement(189..>611)
                     /locus_tag="VQ540_002104"
     CDS             complement(189..>611)
                     /locus_tag="VQ540_002104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine motif-containing protein"
                     /protein_id="HET2545829.1"
                     /translation="KPNEEKPQTEKPEEDKEHDEVSEPTHPESDEKENHAGLNPSADN
                     LYKPSTDTEETEEEAEDTTDEAEIPQVEHSVINAKIAEAEALLEKVTDSSIRQNAVET
                     LTGLKSSLLLGTKDNNTISAEVDSLLALLKESQPTPIQ"
BASE COUNT          155 a          121 c           93 g          242 t
ORIGIN      
        1 gatgaagttt tttctcaact tcttttactt tattaaatag ttttctaaac cggttattta
       61 accatttaat taaccagtaa atagtttact atttaaaatt acttttgtca agtttctgtt
      121 acgtttttct aaaaaagaga agtaacacga aaggttactt ctccataaaa tatgctccat
      181 tcattttact actgtatagg agtcggttga ctttctttta acaaagccaa gagactatct
      241 acttctgctg aaatagtgtt attatctttc gttccgagaa gaagactact ttttagacca
      301 gtcaatgtct ccacagcatt ttgtctaata ctagaatctg ttactttttc tagcaaggcc
      361 tccgcctctg ctatcttagc gttaataaca gaatgctcta cttgaggaat ttcagcctca
      421 tctgtagtat cttcagcttc ttcctctgtc tcttccgtat cagtgcttgg tttataaaga
      481 ttatctgctg aaggatttaa accagcgtga ttctcttttt catcagattc agggtgagtt
      541 ggctcactta cttcatcatg ttccttatct tcctcaggtt tttctgtctg aggtttctcc
      601 tcgtttggtt t
//
LOCUS       DAVBDR010000125          602 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.125, whole genome shotgun sequence.
ACCESSION   DAVBDR010000125 DAVBDR010000000
VERSION     DAVBDR010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 602)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 602)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..602
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.125"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            283..>602
                     /locus_tag="VQ540_002105"
     CDS             283..>602
                     /locus_tag="VQ540_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET2545830.1"
                     /translation="MVLDYFFDKNLVFCLEADNQEQLFDQVATLLEEREIVTPTYREA
                     LITREKSFPTGLDMEFLGKDLPNVAIPHTDIVHNLAEKVVVVRLEKPVTFHNMIAPDK
                     EVEVS"
BASE COUNT          211 a           90 c          113 g          188 t
ORIGIN      
        1 ggttacgata tgatcactga cttcgtcagt cttatctaca acctcaaaac tgtgttttga
       61 gcaacctgcg gctagcttcc tagtttgctc tttgattttc attgagtatt agaacagaaa
      121 aaatacttgg agtatttgtt tgtgtgttta tttttatata acaaactata aacaaaacaa
      181 aaatataaaa aaagagacaa aaaagaacag aaagcaattg acaacggttt catatagtgt
      241 tatacttatg gcataaagtt aatggaaaga agggaaaaac ttatggtatt agattatttc
      301 tttgacaaaa accttgtgtt ttgcttagaa gcggataatc aagaacaact ctttgatcag
      361 gttgcaactt tattggaaga acgagaaatt gtcactccaa cttatcgtga agccttgatc
      421 acgcgtgaaa agtcatttcc aactggttta gatatggaat ttctaggaaa ggacttgcca
      481 aatgtagcga ttcctcatac agatattgtt cataatctag ctgagaaagt ggtggttgtt
      541 cgattagaaa aaccagtaac ttttcacaat atgatagctc ctgataagga agtagaagta
      601 tc
//
LOCUS       DAVBDR010000126          569 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.126, whole genome shotgun sequence.
ACCESSION   DAVBDR010000126 DAVBDR010000000
VERSION     DAVBDR010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 569)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 569)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..569
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.126"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            complement(<1..>569)
                     /locus_tag="VQ540_002106"
     CDS             complement(<1..>569)
                     /locus_tag="VQ540_002106"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2545831.1"
                     /translation="AEALVDAEADALVEADSEAEVLAEADALVDAEADALVLAEADAL
                     VDAEADALVLAEAEALVDAEADALVLAEAEALVDAEADALVLAEADALVLAEAEALVD
                     AEAEALVDADSEALVDAEADALIDADSEADVLAEAEALVDAEAEALVDADSEALVDAE
                     AEADVDAEADALVDAEADALVDAEAEALV"
BASE COUNT          137 a          187 c          130 g          115 t
ORIGIN      
        1 tcaaccagcg cctcagcttc agcatcaacg agtgcgtcgg cttcagcatc aacgagtgca
       61 tcggcttcag catcaacgtc tgcctcagct tcagcgtcaa ccagtgcctc tgaatcggca
      121 tcaaccagtg cttcagcctc agcatcgaca agcgcttcgg cttcagcaag tacatcagct
      181 tctgaatctg catcaataag tgcgtcggct tcagcgtcaa ccagtgcctc tgaatcggca
      241 tcaaccagtg cttcagcctc agcatcaacg agtgcttcgg cttcagcaag tacaagtgcg
      301 tcagcttcag caagcacaag tgcgtcagct tcagcatcaa cgagcgcctc ggcttcagca
      361 agcaccagtg cgtcagcttc agcatcaacg agtgcctcgg cctcagcaag tacaagtgcg
      421 tcagcctcag catcaaccag tgcatcagcc tcagcaagta ccagtgcatc agcttccgca
      481 tcaacgagtg catcagcctc agcaagcacc tcagcttctg aatcggcctc aacgagtgcg
      541 tcagcctcag cgtcaacgag tgcttcggc
//
LOCUS       DAVBDR010000127          565 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.127, whole genome shotgun sequence.
ACCESSION   DAVBDR010000127 DAVBDR010000000
VERSION     DAVBDR010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 565)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 565)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..565
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.127"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            complement(1..565)
                     /locus_tag="VQ540_002107"
                     /pseudo
     CDS             complement(1..565)
                     /locus_tag="VQ540_002107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677188.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          177 a           98 c          121 g          169 t
ORIGIN      
        1 tgaaaaagca agagttgata gagttgatag tggtgtttca agtcttccga ataactcaaa
       61 agcttgttta aaatctcttt attggttaag tgcatacgaa aagtaggacg ataaaaacgt
      121 ttatcactca gtttacggct atcctgttga atgagtttcc agtagcgctt gatagccttg
      181 tattcatggg attttcgatg aaactgattc atgatttgga cacgcacacg actcatagca
      241 cggctaagat gttgtacaat atgaaagcga tcaagaacga ttttagcatt cgggagtgaa
      301 acagtctggg agactgtttc agcctgagcc tagaaatttg aaagcgaagc tgtttagcca
      361 agtcatagta agggctaaac atatccatag taatgatttt gacgcgacat cggacggctc
      421 tatcatattt aagaaagtga tttcgaatga tagcttgtgt tcttccctca agaacagtga
      481 tgatattgag attgttaaaa tcttgcgcaa tgaagctcat ctttcccttt gtaaaagcat
      541 actcatccca agacataatc tcagg
//
LOCUS       DAVBDR010000128          560 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.128, whole genome shotgun sequence.
ACCESSION   DAVBDR010000128 DAVBDR010000000
VERSION     DAVBDR010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 560)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 560)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..560
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.128"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            <1..>560
                     /locus_tag="VQ540_002108"
     CDS             <1..>560
                     /locus_tag="VQ540_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HET2545832.1"
                     /translation="YTDDEIQVAKLAGKYTTEDGYIFDPRDITSDEGDAYVTPHMTHS
                     HWIKKDSLSEAERAAAQAYAKEKGLTPPSTDHQDSGNTEAKGAEAIYNRVKAAKKVPL
                     DRMPYNLQYTVEVKNGSLIIPHYDHYHNIKFEWFDEGLYEAPKGYTLEDLLATVKYYV
                     EHPNERPHSDNGFGNASDHVQRNKNG"
BASE COUNT          183 a          114 c          126 g          137 t
ORIGIN      
        1 tacactgatg atgagattca agtagccaag ttggcaggca agtacacaac agaagacggt
       61 tatatctttg atcctcgtga tataaccagt gatgaggggg atgcctatgt aactccacat
      121 atgacccata gccactggat taaaaaagat agtttgtctg aagctgagag agcggcagcc
      181 caggcttatg ctaaagagaa aggtttgacc cctccttcga cagaccatca ggattcagga
      241 aatactgagg caaaaggagc agaagctatc tacaaccgcg tgaaagcagc taagaaggtg
      301 ccacttgatc gtatgcctta caatcttcaa tatactgtag aagtcaaaaa cggtagttta
      361 atcatacctc attatgacca ttaccataac atcaaatttg agtggtttga cgaaggcctt
      421 tatgaggcac ctaaggggta tactcttgag gatcttttgg cgactgtcaa gtactatgtc
      481 gaacatccaa acgaacgtcc gcattcagat aatggttttg gtaacgctag cgaccatgtt
      541 caaagaaaca aaaatggtca
//
LOCUS       DAVBDR010000129          526 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.129, whole genome shotgun sequence.
ACCESSION   DAVBDR010000129 DAVBDR010000000
VERSION     DAVBDR010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 526)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 526)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..526
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.129"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            complement(23..526)
                     /locus_tag="VQ540_002109"
                     /pseudo
     CDS             complement(23..526)
                     /locus_tag="VQ540_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007897432.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
BASE COUNT          151 a          127 c           87 g          161 t
ORIGIN      
        1 ctgttataga ttcaacgcac tataattgat gacgtttagc tgtttccaac aaactcataa
       61 taatagctct tgctttagct ccttcaaaac tttgagaaaa taaccaccct cgctttttta
      121 aactgagctt aggctaaaag agtccactgg actcttttac tccgtcccat aaccaatgat
      181 ttaatggcgc attcagctag attattggaa aggaccagat gtccgtcttt caaaatagtc
      241 ttaaaggttt ctttatactt gaggctgtat tcaattgccc ttcctagttt tgaacccgat
      301 aaaactgact gacgccggca ccaagcaaag aaatcttcca ttaggttgga gctcttcttg
      361 acgtttctgt agtcgttcat cagctggcaa agcctcccag tctctttcca agaaaaataa
      421 ctgatcacaa taagctaaac ctttagctcc taaggatgat ttatccgctt gcttgggggt
      481 cgcttcaaaa aacttccttc tcacatgcgc ccaacatcca acaagt
//
LOCUS       DAVBDR010000130          526 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.130, whole genome shotgun sequence.
ACCESSION   DAVBDR010000130 DAVBDR010000000
VERSION     DAVBDR010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 526)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 526)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..526
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.130"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            complement(238..325)
                     /locus_tag="VQ540_002110"
     tRNA            complement(238..325)
                     /locus_tag="VQ540_002110"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(289..291),aa:Ser,seq:gct)
     gene            complement(332..405)
                     /locus_tag="VQ540_002111"
     tRNA            complement(332..405)
                     /locus_tag="VQ540_002111"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(369..371),aa:Ile,seq:gat)
     gene            complement(441..511)
                     /locus_tag="VQ540_002112"
     tRNA            complement(441..511)
                     /locus_tag="VQ540_002112"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(477..479),aa:Gly,seq:tcc)
BASE COUNT          176 a          119 c           92 g          139 t
ORIGIN      
        1 gcaatgcctt tggttttcga aactttgaaa actttaaaaa acggattttt atcgctttga
       61 acatcaaaaa agaaaggacg aaatttgtcc tttctcgagc ttagcttttc ttcaacccac
      121 tacagttgac aaagagccat aaaaataact tcagattagt aattcaatta agttttacgg
      181 atctgaagct ttattgtctc taaaaataaa aaagagagtt acaaactctc attaaaacgg
      241 agaataaggg attcgaaccc ttgcgccagt tacccgacct aacgatttag caaaccgtcc
      301 tcttcagcct cttgagtaat tctccaatta atgggcacga gtggactcga accaccgacc
      361 tcacgcttat caggcgtgcg ctctaaccac ctgagctacg cgcccaagtt aaaaaacttg
      421 gtaatttgaa caaagttcaa agcgggtgac gagaatcgaa ctcgcgacaa cagcttggaa
      481 ggctgtagtt ttaccactaa actacacccg cataaatact atcaat
//
LOCUS       DAVBDR010000131          393 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.131, whole genome shotgun sequence.
ACCESSION   DAVBDR010000131 DAVBDR010000000
VERSION     DAVBDR010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 393)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 393)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..393
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.131"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            <1..>393
                     /locus_tag="VQ540_002113"
     CDS             <1..>393
                     /locus_tag="VQ540_002113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HET2545833.1"
                     /translation="YLHLWELSDWDQEGMLCLHELISREEGLVDDIPRLRKYFKTKFR
                     NRILDYIRKQESQKRRYDKEPYEEVGEISHRISEGGLWLDDYYLFHETLRDYRNKQSK
                     EKQEELERVLSNERFRGRQRVLRDLRIVF"
BASE COUNT          143 a           57 c           93 g          100 t
ORIGIN      
        1 taccttcatt tatgggaatt gtcggattgg gaccaagaag gcatgctctg cttacatgaa
       61 ttgattagta gagaagaagg actggtagac gatattccac gtttaaggaa atatttcaaa
      121 accaagtttc gaaatcgaat tttagactat atccgtaagc aggaaagtca gaagcgtaga
      181 tacgataaag aaccctatga agaagtggga gagatcagtc atcgtataag tgaggggggt
      241 ctctggctag atgattatta tctctttcat gaaacactaa gagattatag aaacaaacaa
      301 agtaaagaga aacaagaaga actagaacgc gtcttaagca atgaacgatt tcgagggcgt
      361 caaagagtat taagagactt acgcattgtg ttt
//
LOCUS       DAVBDR010000132          385 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.132, whole genome shotgun sequence.
ACCESSION   DAVBDR010000132 DAVBDR010000000
VERSION     DAVBDR010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 385)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 385)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..385
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.132"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            145..279
                     /gene="rpmH"
                     /locus_tag="VQ540_002114"
     CDS             145..279
                     /gene="rpmH"
                     /locus_tag="VQ540_002114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HET2545834.1"
                     /translation="MKRTYQPSKLRRARKHGFRNRMSTKNGRRVLAARRRKGRKVLAA
                     "
BASE COUNT          132 a           66 c           82 g          105 t
ORIGIN      
        1 ggcttgcatt cgaaaaagct ggaaacattt gcctagagct attgacaaaa gtgaaagaat
       61 cagatagaat agtaaagtat gtttagtaac tgatcacttt atagccggct aaacgaatac
      121 aaaatctatg aggaggtatt catcgtgaaa cgtacttatc aaccaagtaa acttcgtcgt
      181 gcgcgcaaac acggattccg taaccgtatg tcaactaaaa atggtcgtcg cgtattggca
      241 gctcgtcgtc gtaaaggacg caaagttttg gctgcataat ccaaacgaat tctatcaaaa
      301 atcagtagga actcgagtct actgattttt atttttgtaa aaaagttcag tagatgcaaa
      361 tggattcgga agcgatgtta tagta
//
LOCUS       DAVBDR010000133          343 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.133, whole genome shotgun sequence.
ACCESSION   DAVBDR010000133 DAVBDR010000000
VERSION     DAVBDR010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 343)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 343)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..343
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.133"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            complement(1..343)
                     /locus_tag="VQ540_002115"
                     /pseudo
     CDS             complement(1..343)
                     /locus_tag="VQ540_002115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436265.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          106 a           68 c           70 g           99 t
ORIGIN      
        1 taaaatctct ttattggtta aatgcatacg aaaagtagga cgataaaatc gcttatcact
       61 cagtttacgg ctatcctgtt gaatgagttt ccagtagcgc ttgatagcct tgtattcatg
      121 ggatttcgga tgatggcttg tgttctgctc tcaagaacag ttatgatatt gagcttatca
      181 aagtcctgag caataaagct catctccatc tcccgattga aacagtcact ccccggactg
      241 tttcaacgtc ccaagacata atctcaggaa gacgcgaaaa atcatgctca aagtgaaaat
      301 cattgagctt acgaataaca gttgaagttg agatggaaag ctg
//
LOCUS       DAVBDR010000134          299 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.134, whole genome shotgun sequence.
ACCESSION   DAVBDR010000134 DAVBDR010000000
VERSION     DAVBDR010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 299)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 299)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..299
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.134"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            <1..223
                     /locus_tag="VQ540_002116"
     CDS             <1..223
                     /locus_tag="VQ540_002116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2545835.1"
                     /translation="QAQTPRKSSKLKPLTAEDKACNHVLSKERSKVENIFAKVKTLKM
                     FSTTYRNHRKRFGLRMNLIVGIINHELGF"
BASE COUNT          109 a           52 c           54 g           84 t
ORIGIN      
        1 tcaagcacaa actccacgta aatccagcaa actcaagccg ctaacagctg aagataaagc
       61 ctgtaaccat gtgctatcta aggagagaag caaggttgag aacatctttg ccaaagtaaa
      121 aacgcttaaa atgttttcaa caacctatcg aaatcatcgt aaacgcttcg gattacggat
      181 gaatttgatt gttggtatta tcaatcatga actaggattc tagttttgca ggaagtctat
      241 tatcaaaaat accatcagga ttatataaga ttgatacagg aaaagtttta ttttatggt
//
LOCUS       DAVBDR010000135          277 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.135, whole genome shotgun sequence.
ACCESSION   DAVBDR010000135 DAVBDR010000000
VERSION     DAVBDR010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 277)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 277)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..277
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.135"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            <1..>277
                     /locus_tag="VQ540_002117"
     CDS             <1..>277
                     /locus_tag="VQ540_002117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HET2545836.1"
                     /translation="QRIIEAIESALEKVDEYAESYNRLEQLDKEFPDKLKKSILQYAM
                     QGKLVEQDPNDESVEVLLEKIRAEKQKLFEEGKIKKKDLDISIVSQG"
BASE COUNT          126 a           37 c           47 g           67 t
ORIGIN      
        1 aacaacgcat aatagaagca atcgaatcag ctttagaaaa agtagatgaa tatgctgaaa
       61 gttataatag actagaacag ctagataaag aatttccaga taaactaaaa aaatctattc
      121 ttcaatatgc tatgcaagga aaattagttg aacaagaccc aaatgatgaa tcagtcgaag
      181 ttttacttga aaaaatacga gcagaaaaac aaaaactctt tgaagaaggc aagattaaaa
      241 agaaagattt ggacatttct attgtttccc aaggaga
//
LOCUS       DAVBDR010000136          277 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.136, whole genome shotgun sequence.
ACCESSION   DAVBDR010000136 DAVBDR010000000
VERSION     DAVBDR010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 277)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 277)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..277
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.136"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            complement(1..229)
                     /locus_tag="VQ540_002118"
                     /pseudo
     CDS             complement(1..229)
                     /locus_tag="VQ540_002118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
BASE COUNT           81 a           60 c           45 g           91 t
ORIGIN      
        1 cagtattaca tccaccagct attaagaaaa atgattcgcc tgtatgggca tcaacagctc
       61 cataacaata gtgaaattct cgtatatagt gactatggac atgtggacct actcctattg
      121 gagaccaaca agatcccagt ttactgattc taccgaagcc agcctcatct tggtacatca
      181 agcgaacctt atgaaaacgt ctactggttt taaagcgctt tcttttcttc agttgatttc
      241 atatcactat tgtataatgc tttttgattt tagtcta
//
LOCUS       DAVBDR010000137          262 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain KS 061
            SAMEA1678009-rid20175883.denovo.137, whole genome shotgun sequence.
ACCESSION   DAVBDR010000137 DAVBDR010000000
VERSION     DAVBDR010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678009
            Sequence Read Archive: ERR226413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 262)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 262)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980228.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980228.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:09:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,085
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 35
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 64 of 138
            Pseudo Genes (incomplete)         :: 69 of 138
            Pseudo Genes (internal stop)      :: 38 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..262
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678009-rid20175883.denovo.137"
                     /strain="KS 061"
                     /db_xref="taxon:1313"
     gene            complement(80..153)
                     /locus_tag="VQ540_002119"
     tRNA            complement(80..153)
                     /locus_tag="VQ540_002119"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(117..119),aa:Ile,seq:gat)
     gene            complement(188..258)
                     /locus_tag="VQ540_002120"
     tRNA            complement(188..258)
                     /locus_tag="VQ540_002120"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(224..226),aa:Gly,seq:tcc)
BASE COUNT           84 a           70 c           55 g           53 t
ORIGIN      
        1 atagtttata cgggaacaag cccgtgtcct cttagtgaac agataatatt ccaatcccct
       61 agtaatggac taaacactat gggcacgagt ggactcgaac caccgacctc acgcttatca
      121 ggcgtgcgct ctaaccacct gagctacgcg cccaagtcaa aaacttggta caaagaacaa
      181 agttcaaagc gggtgacgag aatcgaactc gcgacaacag cttggaaggc tgtagtttta
      241 ccactaaact acacccgcta aa
//
